LOCUS       DAPBAF010000001       122294 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.001, whole genome shotgun sequence.
ACCESSION   DAPBAF010000001 DAPBAF010000000
VERSION     DAPBAF010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 122294)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 122294)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..122294
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.001"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            591..1280
                     /locus_tag="RD451_000001"
     CDS             591..1280
                     /locus_tag="RD451_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7565300.1"
                     /translation="MKLLIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1267..2475
                     /locus_tag="RD451_000002"
     CDS             1267..2475
                     /locus_tag="RD451_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDT7565301.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2769..4040
                     /gene="serS"
                     /locus_tag="RD451_000003"
     CDS             2769..4040
                     /gene="serS"
                     /locus_tag="RD451_000003"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HDT7565302.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4589..6073)
                     /gene="guaB"
                     /locus_tag="RD451_000004"
     CDS             complement(4589..6073)
                     /gene="guaB"
                     /locus_tag="RD451_000004"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HDT7565303.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6578..7273)
                     /locus_tag="RD451_000005"
     CDS             complement(6578..7273)
                     /locus_tag="RD451_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HDT7565304.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7363..8463)
                     /gene="ychF"
                     /locus_tag="RD451_000006"
     CDS             complement(7363..8463)
                     /gene="ychF"
                     /locus_tag="RD451_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HDT7565305.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8472..8663)
                     /locus_tag="RD451_000007"
     CDS             complement(8472..8663)
                     /locus_tag="RD451_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HDT7565306.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8684..9574)
                     /locus_tag="RD451_000008"
     CDS             complement(8684..9574)
                     /locus_tag="RD451_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HDT7565307.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9561..10328)
                     /locus_tag="RD451_000009"
     CDS             complement(9561..10328)
                     /locus_tag="RD451_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HDT7565308.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10340..11053)
                     /gene="rsmG"
                     /locus_tag="RD451_000010"
     CDS             complement(10340..11053)
                     /gene="rsmG"
                     /locus_tag="RD451_000010"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HDT7565309.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11285..13186)
                     /gene="mnmG"
                     /locus_tag="RD451_000011"
     CDS             complement(11285..13186)
                     /gene="mnmG"
                     /locus_tag="RD451_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HDT7565310.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQR
                     KIAKVSEPA"
     gene            complement(13203..14600)
                     /gene="mnmE"
                     /locus_tag="RD451_000012"
     CDS             complement(13203..14600)
                     /gene="mnmE"
                     /locus_tag="RD451_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HDT7565311.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            14899..15282
                     /locus_tag="RD451_000013"
     CDS             14899..15282
                     /locus_tag="RD451_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565312.1"
                     /translation="MVALSKLYTFERRKYVSPFRSAALEEESDPRINDVVLSTGNINQ
                     KYIVRDIVFVVECLEADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQK
                     KRDGKYFLELFAYGTVIQFIQTTIG"
     gene            complement(15450..16208)
                     /locus_tag="RD451_000014"
     CDS             complement(15450..16208)
                     /locus_tag="RD451_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Jag N-terminal domain-containing protein"
                     /protein_id="HDT7565313.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(16226..17044)
                     /locus_tag="RD451_000015"
     CDS             complement(16226..17044)
                     /locus_tag="RD451_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HDT7565314.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(17041..17397)
                     /gene="rnpA"
                     /locus_tag="RD451_000016"
     CDS             complement(17041..17397)
                     /gene="rnpA"
                     /locus_tag="RD451_000016"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HDT7565315.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17515..17649)
                     /gene="rpmH"
                     /locus_tag="RD451_000017"
     CDS             complement(17515..17649)
                     /gene="rpmH"
                     /locus_tag="RD451_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HDT7565316.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            18172..19506
                     /gene="dnaA"
                     /locus_tag="RD451_000018"
     CDS             18172..19506
                     /gene="dnaA"
                     /locus_tag="RD451_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HDT7565317.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDLKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19704..20834
                     /gene="dnaN"
                     /locus_tag="RD451_000019"
     CDS             19704..20834
                     /gene="dnaN"
                     /locus_tag="RD451_000019"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HDT7565318.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            21063..21305
                     /gene="yaaA"
                     /locus_tag="RD451_000020"
     CDS             21063..21305
                     /gene="yaaA"
                     /locus_tag="RD451_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HDT7565319.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            21292..22416
                     /gene="recF"
                     /locus_tag="RD451_000021"
     CDS             21292..22416
                     /gene="recF"
                     /locus_tag="RD451_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HDT7565320.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQIRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDNRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            22413..24359
                     /gene="gyrB"
                     /locus_tag="RD451_000022"
     CDS             22413..24359
                     /gene="gyrB"
                     /locus_tag="RD451_000022"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HDT7565321.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            24379..26850
                     /gene="gyrA"
                     /locus_tag="RD451_000023"
     CDS             24379..26850
                     /gene="gyrA"
                     /locus_tag="RD451_000023"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HDT7565322.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDIAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKENQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            27086..27385
                     /locus_tag="RD451_000024"
     CDS             27086..27385
                     /locus_tag="RD451_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005226363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HDT7565323.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            27435..27947
                     /gene="ssb"
                     /locus_tag="RD451_000025"
     CDS             27435..27947
                     /gene="ssb"
                     /locus_tag="RD451_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDT7565324.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            27973..28209
                     /locus_tag="RD451_000026"
     CDS             27973..28209
                     /locus_tag="RD451_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HDT7565325.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            28352..30325
                     /locus_tag="RD451_000027"
     CDS             28352..30325
                     /locus_tag="RD451_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HDT7565326.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            30331..30783
                     /gene="rplI"
                     /locus_tag="RD451_000028"
     CDS             30331..30783
                     /gene="rplI"
                     /locus_tag="RD451_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HDT7565327.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            31057..32424
                     /gene="dnaB"
                     /locus_tag="RD451_000029"
     CDS             31057..32424
                     /gene="dnaB"
                     /locus_tag="RD451_000029"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HDT7565328.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            33204..34496
                     /locus_tag="RD451_000030"
     CDS             33204..34496
                     /locus_tag="RD451_000030"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HDT7565329.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
     gene            35283..36146
                     /locus_tag="RD451_000031"
     CDS             35283..36146
                     /locus_tag="RD451_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HDT7565330.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(36275..37897)
                     /locus_tag="RD451_000032"
     CDS             complement(36275..37897)
                     /locus_tag="RD451_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDT7565331.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            38146..38667
                     /locus_tag="RD451_000033"
     CDS             38146..38667
                     /locus_tag="RD451_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HDT7565332.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(38853..40583)
                     /gene="spxB"
                     /locus_tag="RD451_000034"
     CDS             complement(38853..40583)
                     /gene="spxB"
                     /locus_tag="RD451_000034"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HDT7565333.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            40748..41566
                     /locus_tag="RD451_000035"
     CDS             40748..41566
                     /locus_tag="RD451_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HDT7565334.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKRHFAVFGVMSGFIIMMILDVALG"
     gene            complement(41669..41866)
                     /locus_tag="RD451_000036"
     CDS             complement(41669..41866)
                     /locus_tag="RD451_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565335.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            42035..42613
                     /locus_tag="RD451_000037"
     CDS             42035..42613
                     /locus_tag="RD451_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HDT7565336.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            42708..42845
                     /locus_tag="RD451_000038"
     CDS             42708..42845
                     /locus_tag="RD451_000038"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565337.1"
                     /translation="MDQKRIHVGLITSFVTMLIYLDQGHLTWTVVGVVGFLTLFTAIK
                     K"
     gene            complement(43658..44161)
                     /locus_tag="RD451_000039"
     CDS             complement(43658..44161)
                     /locus_tag="RD451_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HDT7565338.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            44520..45545
                     /locus_tag="RD451_000040"
     CDS             44520..45545
                     /locus_tag="RD451_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HDT7565339.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            45868..46746
                     /locus_tag="RD451_000041"
     CDS             45868..46746
                     /locus_tag="RD451_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5596 domain-containing protein"
                     /protein_id="HDT7565340.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDEQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKEQ
                     LLAGEHIGSGLGILTS"
     gene            47222..47338
                     /locus_tag="RD451_000042"
     CDS             47222..47338
                     /locus_tag="RD451_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HDT7565341.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            48266..48604
                     /locus_tag="RD451_000043"
     CDS             48266..48604
                     /locus_tag="RD451_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565342.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            48698..48928
                     /locus_tag="RD451_000044"
     CDS             48698..48928
                     /locus_tag="RD451_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565343.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     gene            49328..49699
                     /locus_tag="RD451_000045"
     CDS             49328..49699
                     /locus_tag="RD451_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HDT7565344.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(49973..50665)
                     /locus_tag="RD451_000046"
     CDS             complement(49973..50665)
                     /locus_tag="RD451_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HDT7565345.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(50668..51453)
                     /locus_tag="RD451_000047"
     CDS             complement(50668..51453)
                     /locus_tag="RD451_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDT7565346.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            51690..53090
                     /gene="lacG"
                     /locus_tag="RD451_000048"
     CDS             51690..53090
                     /gene="lacG"
                     /locus_tag="RD451_000048"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HDT7565347.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            53115..53432
                     /locus_tag="RD451_000049"
     CDS             53115..53432
                     /locus_tag="RD451_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDT7565348.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            53445..55118
                     /locus_tag="RD451_000050"
     CDS             53445..55118
                     /locus_tag="RD451_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HDT7565349.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSGMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            55132..56763
                     /locus_tag="RD451_000051"
     CDS             55132..56763
                     /locus_tag="RD451_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase 53 family protein"
                     /protein_id="HDT7565350.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            complement(57254..58819)
                     /gene="guaA"
                     /locus_tag="RD451_000052"
     CDS             complement(57254..58819)
                     /gene="guaA"
                     /locus_tag="RD451_000052"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HDT7565351.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVNARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(58878..59801)
                     /locus_tag="RD451_000053"
     CDS             complement(58878..59801)
                     /locus_tag="RD451_000053"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HDT7565352.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            59997..60602
                     /locus_tag="RD451_000054"
     CDS             59997..60602
                     /locus_tag="RD451_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDT7565353.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            60910..61926
                     /locus_tag="RD451_000055"
     CDS             60910..61926
                     /locus_tag="RD451_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HDT7565354.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            62067..63368
                     /locus_tag="RD451_000056"
     CDS             62067..63368
                     /locus_tag="RD451_000056"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HDT7565355.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            63414..64076
                     /gene="deoC"
                     /locus_tag="RD451_000057"
     CDS             63414..64076
                     /gene="deoC"
                     /locus_tag="RD451_000057"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HDT7565356.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            64097..64495
                     /locus_tag="RD451_000058"
     CDS             64097..64495
                     /locus_tag="RD451_000058"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HDT7565357.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            64561..65643
                     /locus_tag="RD451_000059"
     CDS             64561..65643
                     /locus_tag="RD451_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HDT7565358.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            65855..67417
                     /locus_tag="RD451_000060"
     CDS             65855..67417
                     /locus_tag="RD451_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7565359.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            67410..68543
                     /locus_tag="RD451_000061"
     CDS             67410..68543
                     /locus_tag="RD451_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7565360.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            68543..69499
                     /locus_tag="RD451_000062"
     CDS             68543..69499
                     /locus_tag="RD451_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7565361.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            69598..70764
                     /gene="deoB"
                     /locus_tag="RD451_000063"
     CDS             69598..70764
                     /gene="deoB"
                     /locus_tag="RD451_000063"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HDT7565362.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            70788..71606
                     /locus_tag="RD451_000064"
     CDS             70788..71606
                     /locus_tag="RD451_000064"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HDT7565363.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            71623..72330
                     /gene="deoD"
                     /locus_tag="RD451_000065"
     CDS             71623..72330
                     /gene="deoD"
                     /locus_tag="RD451_000065"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HDT7565364.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(72628..73314)
                     /gene="gpmA"
                     /locus_tag="RD451_000066"
     CDS             complement(72628..73314)
                     /gene="gpmA"
                     /locus_tag="RD451_000066"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HDT7565365.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(73486..74067)
                     /locus_tag="RD451_000067"
     CDS             complement(73486..74067)
                     /locus_tag="RD451_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDT7565366.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(74200..74883)
                     /gene="rpiA"
                     /locus_tag="RD451_000068"
     CDS             complement(74200..74883)
                     /gene="rpiA"
                     /locus_tag="RD451_000068"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HDT7565367.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            75202..75615
                     /gene="rpsL"
                     /locus_tag="RD451_000069"
     CDS             75202..75615
                     /gene="rpsL"
                     /locus_tag="RD451_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HDT7565368.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            75699..76169
                     /gene="rpsG"
                     /locus_tag="RD451_000070"
     CDS             75699..76169
                     /gene="rpsG"
                     /locus_tag="RD451_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HDT7565369.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            76263..78350
                     /gene="fusA"
                     /locus_tag="RD451_000071"
     CDS             76263..78350
                     /gene="fusA"
                     /locus_tag="RD451_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HDT7565370.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            78522..79709
                     /gene="tuf"
                     /locus_tag="RD451_000072"
     CDS             78522..79709
                     /gene="tuf"
                     /locus_tag="RD451_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HDT7565371.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            80116..80424
                     /gene="rpsJ"
                     /locus_tag="RD451_000073"
     CDS             80116..80424
                     /gene="rpsJ"
                     /locus_tag="RD451_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HDT7565372.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            80455..81084
                     /gene="rplC"
                     /locus_tag="RD451_000074"
     CDS             80455..81084
                     /gene="rplC"
                     /locus_tag="RD451_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HDT7565373.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            81112..81735
                     /gene="rplD"
                     /locus_tag="RD451_000075"
     CDS             81112..81735
                     /gene="rplD"
                     /locus_tag="RD451_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HDT7565374.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            81735..82025
                     /gene="rplW"
                     /locus_tag="RD451_000076"
     CDS             81735..82025
                     /gene="rplW"
                     /locus_tag="RD451_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HDT7565375.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            82064..82897
                     /gene="rplB"
                     /locus_tag="RD451_000077"
     CDS             82064..82897
                     /gene="rplB"
                     /locus_tag="RD451_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HDT7565376.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            82940..83218
                     /gene="rpsS"
                     /locus_tag="RD451_000078"
     CDS             82940..83218
                     /gene="rpsS"
                     /locus_tag="RD451_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HDT7565377.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            83241..83588
                     /gene="rplV"
                     /locus_tag="RD451_000079"
     CDS             83241..83588
                     /gene="rplV"
                     /locus_tag="RD451_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HDT7565378.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            83602..84258
                     /gene="rpsC"
                     /locus_tag="RD451_000080"
     CDS             83602..84258
                     /gene="rpsC"
                     /locus_tag="RD451_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HDT7565379.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            84261..84695
                     /gene="rplP"
                     /locus_tag="RD451_000081"
     CDS             84261..84695
                     /gene="rplP"
                     /locus_tag="RD451_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HDT7565380.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            84685..84873
                     /gene="rpmC"
                     /locus_tag="RD451_000082"
     CDS             84685..84873
                     /gene="rpmC"
                     /locus_tag="RD451_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HDT7565381.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            84898..85164
                     /gene="rpsQ"
                     /locus_tag="RD451_000083"
     CDS             84898..85164
                     /gene="rpsQ"
                     /locus_tag="RD451_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HDT7565382.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            85222..85590
                     /gene="rplN"
                     /locus_tag="RD451_000084"
     CDS             85222..85590
                     /gene="rplN"
                     /locus_tag="RD451_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HDT7565383.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            85627..85935
                     /gene="rplX"
                     /locus_tag="RD451_000085"
     CDS             85627..85935
                     /gene="rplX"
                     /locus_tag="RD451_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HDT7565384.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            85963..86502
                     /gene="rplE"
                     /locus_tag="RD451_000086"
     CDS             85963..86502
                     /gene="rplE"
                     /locus_tag="RD451_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HDT7565385.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            86521..86706
                     /locus_tag="RD451_000087"
     CDS             86521..86706
                     /locus_tag="RD451_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HDT7565386.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            86742..87140
                     /gene="rpsH"
                     /locus_tag="RD451_000088"
     CDS             86742..87140
                     /gene="rpsH"
                     /locus_tag="RD451_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HDT7565387.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            87172..87708
                     /gene="rplF"
                     /locus_tag="RD451_000089"
     CDS             87172..87708
                     /gene="rplF"
                     /locus_tag="RD451_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HDT7565388.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            87869..88225
                     /gene="rplR"
                     /locus_tag="RD451_000090"
     CDS             87869..88225
                     /gene="rplR"
                     /locus_tag="RD451_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HDT7565389.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            88246..88746
                     /gene="rpsE"
                     /locus_tag="RD451_000091"
     CDS             88246..88746
                     /gene="rpsE"
                     /locus_tag="RD451_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HDT7565390.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            88761..88940
                     /gene="rpmD"
                     /locus_tag="RD451_000092"
     CDS             88761..88940
                     /gene="rpmD"
                     /locus_tag="RD451_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HDT7565391.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            88984..89424
                     /gene="rplO"
                     /locus_tag="RD451_000093"
     CDS             88984..89424
                     /gene="rplO"
                     /locus_tag="RD451_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HDT7565392.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            89424..90719
                     /gene="secY"
                     /locus_tag="RD451_000094"
     CDS             89424..90719
                     /gene="secY"
                     /locus_tag="RD451_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HDT7565393.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            90781..91428
                     /locus_tag="RD451_000095"
     CDS             90781..91428
                     /locus_tag="RD451_000095"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HDT7565394.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            91619..91837
                     /gene="infA"
                     /locus_tag="RD451_000096"
     CDS             91619..91837
                     /gene="infA"
                     /locus_tag="RD451_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HDT7565395.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            91870..91986
                     /gene="rpmJ"
                     /locus_tag="RD451_000097"
     CDS             91870..91986
                     /gene="rpmJ"
                     /locus_tag="RD451_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HDT7565396.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            92004..92369
                     /gene="rpsM"
                     /locus_tag="RD451_000098"
     CDS             92004..92369
                     /gene="rpsM"
                     /locus_tag="RD451_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HDT7565397.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            92397..92786
                     /gene="rpsK"
                     /locus_tag="RD451_000099"
     CDS             92397..92786
                     /gene="rpsK"
                     /locus_tag="RD451_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HDT7565398.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            92866..93804
                     /locus_tag="RD451_000100"
     CDS             92866..93804
                     /locus_tag="RD451_000100"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HDT7565399.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            93832..94212
                     /gene="rplQ"
                     /locus_tag="RD451_000101"
     CDS             93832..94212
                     /gene="rplQ"
                     /locus_tag="RD451_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HDT7565400.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            94484..95323
                     /locus_tag="RD451_000102"
     CDS             94484..95323
                     /locus_tag="RD451_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HDT7565401.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMVFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            95299..96168
                     /locus_tag="RD451_000103"
     CDS             95299..96168
                     /locus_tag="RD451_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HDT7565402.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            96158..96955
                     /locus_tag="RD451_000104"
     CDS             96158..96955
                     /locus_tag="RD451_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HDT7565403.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            97158..97904
                     /gene="truA"
                     /locus_tag="RD451_000105"
     CDS             97158..97904
                     /gene="truA"
                     /locus_tag="RD451_000105"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HDT7565404.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKIRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            complement(98359..101028)
                     /locus_tag="RD451_000106"
     CDS             complement(98359..101028)
                     /locus_tag="RD451_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HDT7565405.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFFYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDRGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     TSKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEISFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEQPRNTHRRRRRK"
     gene            complement(101266..101454)
                     /locus_tag="RD451_000107"
     CDS             complement(101266..101454)
                     /locus_tag="RD451_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HDT7565406.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            101724..102086
                     /locus_tag="RD451_000108"
     CDS             101724..102086
                     /locus_tag="RD451_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HDT7565407.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            102138..103820
                     /locus_tag="RD451_000109"
     CDS             102138..103820
                     /locus_tag="RD451_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HDT7565408.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKEIPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            103937..105973
                     /gene="recG"
                     /locus_tag="RD451_000110"
     CDS             103937..105973
                     /gene="recG"
                     /locus_tag="RD451_000110"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HDT7565409.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKQFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LITGSTKAKERRELLEKLEQGEINVVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            106022..107023
                     /gene="plsX"
                     /locus_tag="RD451_000111"
     CDS             106022..107023
                     /gene="plsX"
                     /locus_tag="RD451_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HDT7565410.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            107145..107387
                     /gene="acpP"
                     /locus_tag="RD451_000112"
     CDS             107145..107387
                     /gene="acpP"
                     /locus_tag="RD451_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HDT7565411.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            107655..108659
                     /locus_tag="RD451_000113"
     CDS             107655..108659
                     /locus_tag="RD451_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7565412.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            108660..109604
                     /locus_tag="RD451_000114"
     CDS             108660..109604
                     /locus_tag="RD451_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7565413.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            109604..110566
                     /locus_tag="RD451_000115"
     CDS             109604..110566
                     /locus_tag="RD451_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7565414.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            110593..111507
                     /locus_tag="RD451_000116"
     CDS             110593..111507
                     /locus_tag="RD451_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7565415.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            111533..113314
                     /locus_tag="RD451_000117"
     CDS             111533..113314
                     /locus_tag="RD451_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HDT7565416.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            113662..114348
                     /locus_tag="RD451_000118"
     CDS             113662..114348
                     /locus_tag="RD451_000118"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HDT7565417.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            114368..117949
                     /gene="smc"
                     /locus_tag="RD451_000119"
     CDS             114368..117949
                     /gene="smc"
                     /locus_tag="RD451_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HDT7565418.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIEAALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            117958..118767
                     /locus_tag="RD451_000120"
     CDS             117958..118767
                     /locus_tag="RD451_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDT7565419.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            118778..119776
                     /gene="ftsY"
                     /locus_tag="RD451_000121"
     CDS             118778..119776
                     /gene="ftsY"
                     /locus_tag="RD451_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HDT7565420.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            119963..122230
                     /gene="gshAB"
                     /locus_tag="RD451_000122"
     CDS             119963..122230
                     /gene="gshAB"
                     /locus_tag="RD451_000122"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HDT7565421.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKEYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
BASE COUNT        38834 a        22450 c        25607 g        35403 t
ORIGIN      
        1 ggagtgtttc ccgattcgtt tttggctgcc gtagcaactt ttatatcata tcagagagac
       61 aagtaattgt caactctttt ttaaaagttt tttcgatttc gtttttcgaa atcttccagc
      121 aactcattta tcataactta tcgtttgtta tttgtcaaga acttttttga agtttttttc
      181 gatagaatca agcttcgcaa gtggttcttt tttaacgact cagttatctt atcatgtcat
      241 ttccaacatg tcaacaactt attttttatt atttaataag ttattggtgt tcttttgaac
      301 aaataataat atatcaacat cacatgtgaa agtcaataag aaaatgctta tttatcaaca
      361 tttctagctt acatgatcat tggttagttc tggtcctttt tcgttcgtct ttataactcc
      421 gagagacgta aaatcctttt gttttcagtt taatgttcat gttcttgtct tattcacacc
      481 aactagatgt ctcaccttct aaaattttcc ttaacaaagt gctgctttta tctatttctg
      541 cttttttttg ctagaataat agtaacaata tgactctgga ggatttattt atgaaacttt
      601 tgattgctga cgatgataaa gaaatcgttg aattattaag tatctatgtt cacaatgagg
      661 ggtatgaagc agtaaaggct tatgatggga aagaagcatt atctaaaatc agaacaatcc
      721 ctgatattga attacttatt ttagatatca tgatgcctga gatggatggg atgcaagtag
      781 tgaaagagct acgaaaagaa tcccaaatac caatcattat gctgacagca aaaactactg
      841 atatggataa gatcaaagga ctggtcgctg gtgcagatga ttatgtgacc aagccattta
      901 atccgttaga agtaatggct agagtaaagt ctttattacg gcgtacaaaa atgcagattg
      961 ccccagatca gcctgatgta ttagaagtaa atgcattaat catcaataaa gactctcatg
     1021 aagttaaaac aatcgatggg aaagaaatcc agttaacagc tttggaattc ggtatcctct
     1081 acttgcttgc tagtcatcct aatcgagtat ttagcgcgga tgaaattttt gagcgtgttt
     1141 ggaaacaaga aagtattgtc tctgctaaaa ctgtcatggt tcacgttagt catttaagag
     1201 ataagattga agaagcaact ggtggtgaaa aagtcattca aaccgtttgg ggagtgggct
     1261 ataaaattga cgcaagatag taaacgagca actgaaaaac gccgtcggat caatttgact
     1321 tcaaaagaaa tcagcgaatt gttagcggaa ggaatcatca cgattatcct tttgcttcta
     1381 ttaaatgttt ctattctggt tgttatcagt tcggtgatca acagttcacc ttctttgacg
     1441 aatgcgattt gggattcaaa gaatattttt gcagaacgat tgaacactga tttgttctgg
     1501 aacggccgga attttattat tccctttttc tttctattag atattggtgt tttgtattgg
     1561 cgcttgattc gaagatatcg ccaaatgcaa ttgcggcata tcatcagcga acttcactac
     1621 atcgcaaacg gaaattatga tcatcgtatc ccttttgaac tgagtggtga cttaagccga
     1681 gtggtaacaa gtatcaatgg attggtggat agtaccgtag cagcgattga agacgaacgt
     1741 aaaatcgaaa aatcaaaaga tgaattgatc acgaatgtca gtcatgatat ccgtacccca
     1801 ctcacgtcca tcattggata cctaggactg atagaagatg gccagtatca ctcagaagaa
     1861 gatcttttaa agtatacgca tactgcttat atcaaagcaa agcagatgaa atctttagtg
     1921 gacgacttat ttgaatacac taaggtacgc cagcctgctg tcccggtgaa tttttctgcc
     1981 tttgacatga tccagttgat cgaacagtta gcagctgatt ttgagttgga agcttctaaa
     2041 aaaaatatcc aaatacttgt tcaatcaaaa gtagactccc ttatcatgga tggcgatacc
     2101 gaaaaacttg tacgtgtctt caataatctt ttgacgaatg cgttgaaata cggaaaagga
     2161 gcaacgaaga tcgtaatcga agtagaacgt atcggttcag aagttgttgc aacagtcaaa
     2221 aataacggag caatgatccc acaacaggca atcgataatc tattcgaccg tttttatcgt
     2281 gtagaagaat ctcgttcaca agcaactgga ggaactggac ttggtttagc aatcgctcaa
     2341 agcattgtgg ctttgcacgg cggatacatt tatgcaaaat cagataagca atggacttct
     2401 ttcatcatgc accttccaat caagaaaaat gaaaaattac ctattgatac acaggaagtt
     2461 attgacgaaa gctgaaatat tcgctattct tattacaatt attagaataa atgaaaaaca
     2521 cagaacccag tacactttat tctttttcag agagctgatg gcaggtgtaa atcagcaaag
     2581 gataatttgg aagttccagt tcgtttacgt gccctttcga aataagaaag gtcggttcaa
     2641 cagccgttat gtgttcaaca agtgcagctg acgctgaact tgggtggtac cgcgaatttc
     2701 agactgattc gtcccaagaa taatgggatg gatcagtctt tttttatttt caaaaaggag
     2761 gaaatcatat gttagatgta aaaatgatgc gacaaaatat tgaagaagta caagaaaaat
     2821 tgatgactcg gggcgtaaaa aaagaaacat tagctgaatt catggaacta gatgaaaatc
     2881 gtcgtaagct actagtcaaa agtgaagaat taaaaaaata tcgaaatgat gtttctgctg
     2941 agatcgccca attgaagcgt gcaaaagaag atgcttctgc taaaatcgct gaaatgaaag
     3001 aagtcggtgg caacatcaaa gcattggata ctgaaattgc tgaagtggat gaaaaattga
     3061 aacaaattgc aactactttg ccaaaccttc cccatgattc tgtgccagtt ggaacagatg
     3121 aagaggacaa tgtagaaatc cgtcgttgga gcgaaccacg tacatttgct tttgaaccaa
     3181 aaccacactg ggaaattgca gaaaatcttg atattttaga ttttgaacgt ggcgcaaaag
     3241 tagccggtag ccgttttgtc tattacaaag gattaggtgc tcgattagaa cgtgctgtct
     3301 acaacttcat gcttgatcag catatttacg aacacggcta tactgaaatg atcactcctt
     3361 atatcgtcaa cagtaaagcg atgtttggta cgggacaatt tccaaaattc aaagaagatg
     3421 ttttccaatt ggagaatact gatctaacat taatcccaac agctgaagta ccattaacta
     3481 actattataa tgatgaaatt ttagatggtg cagatttacc tatttatttc actgcactaa
     3541 gccctgcttt tcgttctgaa gccggaagtg ctggtcggga tacacgagga ctgattcgtc
     3601 ttcaccaatt caataaagta gaaatggtca aattttcgga tgtagagcat tcttacgaag
     3661 aattggaaaa aatgacagct gatgcagaag atatcttgaa aaaattgcat ttgccttatc
     3721 gtgtgatggc cttatcaact ggagacatgg gcttttctgc agctaaaact tatgacttag
     3781 aagtatggat acctgcacaa gatacttatc gtgaaatcag ttcttgttct aactgtgaag
     3841 atttccaagc acgccgcgca atgatccgtt atcgcgataa tgatggaaaa atccactata
     3901 ctcatactct gaatggttca ggacttgcag ttggccgtac agtagctgcc attttggaaa
     3961 actaccaaaa tgaagatggt tctgtcacag ttccagaagc gctcgttcct tatatgggga
     4021 atctgaaagt tattaaataa agaggctgtg aaaaagccgc ttagtttcga gtattaagaa
     4081 aaattttgtg aaaatggctt tccacatttt tgcataaatt ggacttaata ccgagaaact
     4141 ggcttttgaa caccatttat cgagaggttg tgaaatcagc gaattaacct gagtattaga
     4201 gaaaaaaatg gaaaaatagt ccctcatatt ttaccgtttg ttgaactaat accgagggtc
     4261 agctgattga acaccgttta gtggagaggt cgtaagccta ccccccagct cctagttaca
     4321 aggacaaatt caaaaaacag ctcttcatat tttatgaatg ttgtacttgt gattcggagg
     4381 tggcaaggga acactgttta ttcaaaaaga ggctgggaca gaagcgttta actccaagaa
     4441 ataagaagaa attcacgaaa attgcttttc aaatttttgt gaatttcttc ttatttccga
     4501 aggagttgct tctacttccg ccgtttatac gtgtttagag cgtgagacaa aagtgttctt
     4561 tacttttgtc ccacgctctt taatgttttt aagattcaac tgaatagttt ggtgcttctt
     4621 ttgtgatttg tacatcatga gggtgtgatt cttttaatcc actgccgctc atttggataa
     4681 attgcgcttc atcacgtaat tgctgtagat tggctgcccc aacataaccc attcctgaac
     4741 gcaaaccgcc gatcatttgg aaaataatat ctgcaacact tcctttataa gcaacccgac
     4801 cttcgattcc ttctggtact aatttatttg cttcattgac actaccttgg aagtaacggt
     4861 cttttgaacc tttttccatc gcgcctaatg agcccatacc tcggtatgtt ttgaatcgac
     4921 gtccttggaa gatttcgaat tcacctggtg attcatctgt ccctgccaac atacttccta
     4981 gcatcactgc atgtccgccg gcagctaatg ctttgacgat gtcaccagaa tatttgatcc
     5041 ctccgtctgc aataatcgct ttgccatatt gacgagcaac tgatgctgca tcataaatag
     5101 ctgtgagctg aggtacacct acaccggcta ccacacgtgt cgtacaaatc gatcctggtc
     5161 cgataccaac ttttacgaca tctacacctg catcatataa agcttttgtc gcttcagccg
     5221 tcgcaacgtt tcctgcaatc aatgttgcat ctgcaaaagt tgaacggatt tcttgaattt
     5281 ttcggatcac acctgcacta tgtccatgag ctgtatcgat gatgattgca tctgcccctg
     5341 cttctaataa agcattcgca cgctcaaatg tatcgcttgt tacaccaacg gctgctgcta
     5401 caagcaatcg accatgttca tcttttgctg catttggaaa ttcgatcact ttctcgatgt
     5461 ctttgatcgt gatcaatccg cttaaacgac cttcgttatc tacgattggt aatttttcga
     5521 ttttatgttt ttgcaaaatc ttttctgcat cttttagaga ggtacctact ggggcagtca
     5581 ctaagttgtc ttttgtcatc acatcagcaa tcggcatgtg ataatctgtt acaaaacgca
     5641 tgtcgcggtt tgtaattatc cctaccaatt ttctgttttc aagtgtttca acgattggca
     5701 caccactgat acgatatttg ctcatcaatt cttctgcgtc tgctacaaga tgctgtggcg
     5761 ttaagaagaa cggatcaatg attacgccac tttcagaacg tttgactttt cttacttcat
     5821 ccgcttgctg gctgatcgtc atgtttttat ggatcacacc tagtccgcct tgtcttgcca
     5881 tagcaatggc catcttgctg tcggtaacag tatccatact tgcactgatg attggaatat
     5941 tcaacttaat atttttagct aattgtacgc tcatatccac ttcgtttggt aacacgtgac
     6001 tttctgctgg tatcaataag acatcatcaa aagtaaatcc ttttttcgtg aactttgttt
     6061 cccagttgga catttttagt accactcctc taatttagtt tatctattaa aataattgat
     6121 tttttcattt aagtcaatga tctacttgga atcaagttag ctttctcata gaataccaat
     6181 ataaagcgtt tacatctgtg tgtattaaaa gagattgtaa aaaagctgtc ctgcatcaag
     6241 taataagaac agccaatcaa aaacagcttc tcatgttttt gaattggttg ggtttattac
     6301 cgcagatgca aacttttgaa caccgtttag tggagaggct gtgaaaaagc tgcttagttt
     6361 cgagtagtaa gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa attggactta
     6421 ataccgagaa actggctttt gaacaccgtt tatcgtaaaa agggactgtg acaagacttt
     6481 tgtcacagtc ccttactatt atttaactat ggataaacaa aatgaggttc tttactaccc
     6541 ctagatatct agcaaaatag ctgatctttt tgctagttta tcttcttggg acggataaac
     6601 ttccaataat cccgtatttt ttcttcaagt agtaacggat tgctaaagca gttgccccga
     6661 taatgataac tactactgga tctaatactg gattgataac tggtggcaat agtgttgtcg
     6721 cagaaaacag tacgacccaa agaagtgtcg ttccacctag gataagcaat gtcttaccca
     6781 ttcctggttt cttgcttcga tctgctccgg gatattcata ttgatagatg tatttgtaca
     6841 tcatataaaa gacccagcca ccgattgcag aacctagaac gagtgtagaa aagccataag
     6901 ctggcgttgt tccacgtgaa aacaatccgg taatcgcaat catgatactt aatagaccaa
     6961 gcaacagcaa cgtattatct aaccacatca ataaaggggt ggatgaattt tttacttctg
     7021 ctggcttatt gatgattgct tccgttcttt cagagactgt cccaaacaat tgacgggctg
     7081 ttcttccgcc tttttgttct gcaactaaag taggcagaat gtcatgaagg gcttttactt
     7141 tttcttcttc agacaaattc gctgcttcta aagatttttt caaatcaaaa atgtactgtt
     7201 gatttctttt ggttaatttt gtttctaaac tattgttttc ttttacgatt gctcgtaatt
     7261 gttctggttc cattatctaa tagtcctcct tagccgttcc ttttctcaac ggtcgtcaca
     7321 aaagacattc taccatattc tacagctagt ttgatagccc ttttacacat taaagcggaa
     7381 taacattacg tcgccgtctt gtacgacata atcttttcct tctaatcgaa cacgtccagc
     7441 ttcttttgct gcatgcatgt ttccgtaatg atccaagtct tcaaaagaga cagtttctgc
     7501 acggataaat ccgcgttcga aatctgaatg gatgattcct gctgcttgtg gtgctttgat
     7561 tccttttttg aatgtccaag cacgtacttc ttgttcccca gcagtaaagt aagtagctaa
     7621 gcctaacaaa tcataagcag cacggatcaa ctgatccaaa cctgattctt cgattcctaa
     7681 agcttctaaa aattccgctt tgtcttcttc atctaattct gcgatttctt cttctgcacg
     7741 agcactgacc acgatcactt ctgcattttc ttctgcagca aagttgcgca cttcttgtac
     7801 ataatgattc gcgtctgcat ctgctacgtc atcttctgag acattggcta cataaagaat
     7861 tggttttgtc gtcaataaaa atagtgattt aacgattttt tgttcttctt cagtaaattc
     7921 gatcgttcgg gcagattttc cttcttccag tacaggtttg attttatcca gtacagctag
     7981 ttctgccact gcatctttat ctttggtttt agcaactttt gctacacgag tatagcgttt
     8041 gttgatagat tctaagtctg ctaacactag ttccaagttg atcgtatcaa tatcttctag
     8101 tggatcaaca cgtccttcta cgtgagtaat attatcatca tcaaaacagc gaacaacgtg
     8161 acaaatagcg tctacttggc ggatatggct taagaattga tttcccaaac cttctccttt
     8221 acttgcgcct tttacgattc cagcaatatc tgtaaattca aaagtcgtcg gaacagtttt
     8281 tttcggatgt acaagttctg ttaagcgttg caaacgccag tcaggtactt ctaccatccc
     8341 tacgttgggg tcgatcgtcg caaagggata gtttgctgct tctgctcctg cttttgtgat
     8401 cgcattaaac aaagttgatt ttcctacgtt gggcaaccca acaattccag cagtcaatgc
     8461 cataaattta ttcactcttt ctctgcattt ttttcaatta ctttttttaa tttcttttca
     8521 aaatctcgac gggtcatcat gacgatatgt ccgcaattca tacatctgat tttgatatct
     8581 gcgcccattc gaatgacttc ccagcgattc gtctggcaag cgtgaggttt tttcatttca
     8641 acgatatcgt gcaagtcgta cataaaaata gcctcctttt tgtttattct tcatcaaatt
     8701 gaatattcaa gatatcaaga attcgagtca aatctttttg agaaagatat tcaatctcga
     8761 tcttaccttt cccatttttt tcttggatag ctacacttgt accaaattta tccatcaaac
     8821 gatcttcgct ttctcggata taatatggtt tttcctttgc tagccttggg atttttttct
     8881 tttcttttcc atcattttga tttaactcag aaacaagctg ttccagttgg cggacagtta
     8941 aattttcagt tactgcacga ttggctaatt tcaagatcaa tgttttattt tttaaaccta
     9001 acagcgtacg ggcttgtccc atagataaac gctgatcttg taccatttcc ttgacaagat
     9061 ccggtaaaga aagcaagcgc aaataattgg cgatataagg tctgctcttt cctaaacgac
     9121 tagctacttc tgcttgtgtt agtttcaggt ttttcatcag catctcatat gcttctgctt
     9181 cttctaacgg attcagatct tctcgctgca agttttccag cactgctact tgcatcatcg
     9241 cttcttcgtc aaagtctcta acgatagcag ggatcgtttc tttttcagct agtttggacg
     9301 ctcgaaaacg tcgctcccct gcaataatct catatccttt tactgcggaa cggcgtacga
     9361 tgatgggttg aaagacacct gattgttcaa tagaattagc tagttcctgc aaagatactt
     9421 cttcaaatgt tttacggggc tgatacggat ttggtcgcag ctcattcaat ggtagctgga
     9481 caacggtatc atcttttaca tccaccgtct ctaagttttc taaatcttga aacagtgcat
     9541 cgattcctcg gcctaatcct ttacttttct tcacgactta ccacttcctt tgccaatgct
     9601 tggtagactt cagctcctcg agaacgtgga tcgtagtcga tgatcggttt tccatgacta
     9661 ggtgcttctg ataaacgaat atttcttgga atgatcgttt cgtaaacttt ttcgcggaag
     9721 tatttacgta cttcttctac gacttcattt cccagatttg ttcgtgcatc atacattgtc
     9781 agtaagactc cctcgatctc taattctgga ttaaagtgtt tttggactaa acgaaccgta
     9841 ttcagtaatt ggcttaatcc ttccaatgcg taatactcac actgaacagg tatcaaaatc
     9901 gaatcacttg ctgtaaatga attgattgtc agatggccaa gagaaggcgg gcaatcgatc
     9961 aaaatataat catactgact gcttacttct gctaaagatc cttttaatct tgattctctt
    10021 gccatcattg acgtcaattc gatctctgct cctgctaatt ggagagtcgc aggcacaata
    10081 ctcaaatttt cgtgttcagt gatcaaagtt gcctcatcaa ttggcaattc attgactaga
    10141 acatcataga tgtctcttgt cacatcaggt tttctgatcc cgacaccact ggtagcattt
    10201 ccttgtgcat ccatatccac tagcaatact tttttgccaa ggctagcaag acaagcacct
    10261 agattcaccg tcgtcgttgt tttgccgacg ccaccttttt ggttcgcaac agatattatt
    10321 tgtgccatct cttctcctcc tatttgattg gctgcttatt aggcagtccg ggctttcttg
    10381 ggtatttctt tggggttggt ttcttttttt gaataacgat gatatgccgt tgatcagaga
    10441 cattcggcaa ggtaaccgcc tcttctttga ggaatttacc acctaataaa gcaatcgctt
    10501 gttttgcttc tgtcaattcc tcttcacttt ttgctgcttt caatgcataa aaatagcctt
    10561 cttgtttagc caagggcaaa cacaattccg ctaacacatt caaacgagca accgcacgag
    10621 cagtgacaag gtcaaatgat gcacgaaagt gaggattttg cccaaatgtt tctgcccggt
    10681 catgatataa ggaagcatcg attcctaata atcgggttaa ctcagataag aaggttattc
    10741 gtttattcag agaatcaacg atcgttatct gcagttctgg aaaggcaatt tttaaaggta
    10801 tgctaggaaa ccctgccccc gaaccaacat cgcataaaga taaaggttgc gtaaagtcta
    10861 cttcaaatgc taatgtaagt gaatcgtaaa aatgcttcag atatacgtct ttttcatccg
    10921 taatagctgt aaggttcatc ttttcgttcc attcgactaa tgtccgataa taaatagcga
    10981 attgattcat ttgatgatcg gtaagctcta tccctttttc tgccaaggat tggcgaaatt
    11041 cttctggtat cataaatatt cctttcattg tgaaacagca attgtttcac agattctctc
    11101 cctactttaa cgcaaaatct ctagacatgc aatccttcca tatggattct taaaaatttg
    11161 aaaagtaaga aaagccgata gactttttct ttctagtatg actcataaaa tatacacaga
    11221 agagagaact agctttgagc aatttctgca aaaactagtt ctctcttcta tttattatta
    11281 cgtattacgc tggttcactg actttcgcaa tcttcctttg ttcgatatag accattagga
    11341 tacttaggtc tgcagggttt acgccactga ttcggctagc ttgggcaatt gtttctggtt
    11401 ggattttctg caatttttgt tttgcttctg ttgctaatcc gttgattgct gcgtagtcga
    11461 tgttttctgg aatctttttc gcttccatgc gttttaattt ttctactttt tccatggctt
    11521 ttttgatgta gccttcatat ttgatttgga tttctacttg ttcgatttct tttcgtgtca
    11581 attcttcatt ttctggaata aaccgtagaa gttctgcata agtaatctca ggacgtctta
    11641 aaaagtcgct tgctagtaca ccatctttta atggtgccgc attaatcgtt gctaaaaagt
    11701 cttggacttc ttctgttggt ttgattcgta cattcatcaa acgtttgatt tcttgttcaa
    11761 ctgcttcttt tttcttcaaa taattcttgt attgatcttc ttttactaag cctacacggt
    11821 gacccatttc tgttaatcgc aaatctgcat tatcatgacg taaaagcaga cggtattcag
    11881 cacgtgaagt cagcaaacga taaggttcgt tcgttccttt tgttaccaaa tcatcgatca
    11941 tgacaccgat gtaaccgtca cttcgtttga tcactaaagg ttcttttccc tgaactttca
    12001 aagctgcatt gataccggca atcagccctt gtccagccgc ttcttcataa ccgcttgtac
    12061 catttgtttg tccagctgta taaagatttt caacgacttt agtttctaat gtcggacgga
    12121 gctggtgtgg ctctactacg tcatattcga tagcatatcc tgtacgcatc atttctactt
    12181 tttctaatcc agcaatagaa tgaagcatgt tgacttgaac atcctctggt aaagaagtag
    12241 ataaaccttg aacatagact tcttccgtat ttaagccttc tggttccaaa aataattgat
    12301 gacgtggttt gtctgcaaaa cgcacgatct tatcttcgat ggatggacaa tagcgagcgc
    12361 ctaccccttc aacgatccct gtaaacattg gggcacgatg taagttgtct cgaataattt
    12421 ggtgagtcgt ctcacctgta taggtcagcc agcaagattc ctgatctagt ttataggcac
    12481 tatctggtgt gctgaagcta aaatgattcg gctctttgtc accaggctgc tcttctgtaa
    12541 cagaatagtc gatcgtactt gattttactc gaggcggtgt tcctgttttg aaccgttcga
    12601 tagcaaagcc aagttctttt agatgattcg ctagtccaat agaaggttga gagttattcg
    12661 gacctgatga atatttcaat tcaccgataa tgatttctcc gcgaagtgct gttccggctg
    12721 taataacaac tgctttggcc cggtagctcg ctcctgtgga cgtcactact ccatgacaaa
    12781 caccatcttc gacgatcagt tcttcgacga ttccttgtct tagcgtcaaa tttggttctt
    12841 tttcgatcgt atgtttcatt tctgttgaat aagcatgttt gtctgcttgt gctcgcaatg
    12901 ctcggacagc tgggcctttt cctgtgttca acatacgcat ttggatatag gttttatcga
    12961 tattcttacc catttctccg cctaacgcat cgatttctcg aacgacaacg cctttagctg
    13021 gtccgcctac agaaggatta catggcatga atgctaccat gtccaaattt attgtcagta
    13081 ataatgtttt tgatcccata cgtgcagcag caagtgcagc ttctgaaccg gcgtgtcctg
    13141 cgccaacaac gatcacgtca tacgcatctg cttcataatg ttccaatcgt ttgttcctcc
    13201 ttttattttc ctaaacaaaa ttgactgaat aattgagtga ttagctcatc ttgtacactg
    13261 tcgccgacaa cttctcctag atagtcccag caacgcgtca tatctatttg aacgagatcc
    13321 acaggcattc ctgaatcaat acctgcaatg acttcttcaa gtgagaggga agctttttct
    13381 aacaacgcga tatggcgggt attagaaaca taagtagcgt ctctttctcc tgtttctccg
    13441 ctgaagaata aatcagaaat agctgattcc aaacgatcta gtccgtcgtt tttagctacg
    13501 gaaattgaaa aaactggttc attttcgatc aatttcttca atttttcttg ttccagctgt
    13561 gctggcaaat ctgttttatt tagaagaatg atccgtttca atccacttgt cgcttccaat
    13621 aattgttcat cttctgctgt cagtggttcg ctttggttta gaacaagtaa gatcaagtct
    13681 gcttctgcta atgcttttcg gcttctttcg accccgatcc gttccaccac atcttctgtt
    13741 tcccgaattc cagctgtatc gattagcttg agcggtaccc cccgaacatt gacatactct
    13801 tcgattacat ctcgagtcgt tcctgcaata tccgtaacga ttgctttttc ttctcttaac
    13861 aaatggttta acaaacttga tttgccgaca tttggccggc cgatgattgc cgtacttaac
    13921 ccttcccgca gaaccttccc ttgcttggat gtagcaagta gcgcttggat tctttgttgg
    13981 atcatctgcg ctttttcaag caataacttc gtagtcaatt cttcgacatc atcatattct
    14041 ggataatcaa tatttacttc tacttgtgct aatgtctcta aaatctcttg tctcaatgag
    14101 cggatcaaag cagacagatt gccgtctaac tgattaagag ctagtcccat tgctttgtct
    14161 gtttttgccc gaatcaaatc catcacagct tctgcctgtg aaaggtcaac acgaccattc
    14221 aagaatgctc gttttgtgaa ttcgcctggc tcagctaatc ttgcaccttc tcttaacaat
    14281 agctgcaaaa tttgattgac tacaacgatc ccaccgtgac aattgatttc tactacatct
    14341 tcccgcgtaa atgtctttgg tgctctcatc acggagacca tgacttcatc gacaagctga
    14401 ttgctcttgg gatcaacgat atgtccataa tggatcgtat gacttggtac ttctgataat
    14461 cgtttgtttc cagattgata aactttatct gctagttgca cagcttgatc gccacttaaa
    14521 cgaacgatac tgattgcacc ttctccaggt ggggtagaaa ttgccgcaat cgtatcaaat
    14581 tctaaagtaa tttcagccat tttttcactt cctttttcat tttgcgcaca aaaaaagtgc
    14641 ccactccacc ctttatgcac aataaacggt gaacttcgca ctttgactgc ttgttcttga
    14701 ttaaattctg gtcatagatt atcacacttg ctataaggaa tcaagtgttt aaaacaatta
    14761 gatgaagttg agcctgttct gcttccatta ccttatattt aattgtcctt ggatgtctct
    14821 ttgcgttctt tggtttattc gaagagaaga tactgtataa acaaggcttt atctttctta
    14881 aaaaaaacgg tacactaaat ggtagcgcta tctaaactat acacttttga aaggagaaaa
    14941 tatgtgagcc cgttcagatc tgctgcattg gaagaagaaa gtgaccctcg gatcaacgat
    15001 gtcgttttat ctacagggaa tatcaaccag aaatatatcg tccgcgatat cgtttttgtt
    15061 gtggaatgct tagaagctga tttgtttgac ccatcttttc ccaaagatga ccttttctta
    15121 acaacgaaga ggaaattaaa gacgaaggta cttgaatatg gtgcgaatgc agtaatcaac
    15181 tgtcattttg agtatcagca aaaaaaacgc gacggaaagt attttctgga actttttgct
    15241 tatggaacag tgatccaatt tatccaaaca acgattggtt aaatgaaaca gacaaaaaaa
    15301 gcggatcaaa actgaagaca gtttcgatcc gcttttttct atcaaagtta gtgactactt
    15361 catcgtatac tctgataaga atgatttcta gtaaaatata cttggtttga aaaactttgt
    15421 caacgtgatt tattcaaaaa gtaatggaat caataatatt ttttagcagg ttctactact
    15481 aaataacgat aaggttcctc accttccgaa tgtgttttta catgttcatc tttgcttaat
    15541 gcagcatgga tttgtttacg ttcaaatgca ggcattggtt ctaagaaaac aggctgccct
    15601 gtccgtttta ctttttcagc cgtgcgatca gctaaacgct gaatgatctc ttggcgcttt
    15661 tcacggtaat tgcctacatt gactactaca gacagcttat ttcttgctaa acgatggatg
    15721 aagacttgtg ccagatattg caatgcattc agtgtttttc catgtttccc aatcagtatg
    15781 ccttgctttt gtgtttctaa atggaaaaca accatattat ttgattctct ttccattttg
    15841 acaagagctg gagcatcaag ctgttttgaa atttcagtaa gataaactgc caattccgtt
    15901 aaagctgctt catcacctag ctcacttact tcttctgttt tttcttcaag aatcgtttcg
    15961 ttgactacct cgatctcagc tgttggttct tcttccaaaa tttcttctac agtctgttct
    16021 actgtttcag aaactttttc gctgatactt ggctggatcg aaagccgtgc attctttcga
    16081 cccattccta ggaaaccttt ttttccttct tccagtattt cgatttcgac ttggtctttg
    16141 gccaaaccca aatcagccag acctagttgg acagcttcgt ctattgttgc agcttcataa
    16201 atcggcatta gcattacctc ccctattatt tccgtttttt cttaggattc attgctttct
    16261 taagagcacg ttctctttcg cggattctcc gtgcttcttc ttcacgctct tttcgaattt
    16321 tgaaagggtt gttgatcagc agcgtttgta caacttggaa ggcattggaa actacccagt
    16381 ataatgaaag accgctggct aaattgacac ccatcactaa aatcattaca ggcatcacga
    16441 aattcatgat cttcattgat gcattcgatt caatttgact catgctagat aaatacgtac
    16501 ttgcaaaagt aaagattgct gctaaaatcg gcaaaataaa tgttggatcc gcgttcccta
    16561 agttcaacca taagaaatgc ccttgtttca actctggtac acgtgaaata gattgccata
    16621 acgccatcaa gattggcatt tgtactaata aaggaagaca accagcatat ggattgacgc
    16681 cattttctgc atataaacgc tgctgctctt ctcttaactt actttgtgtt tccggatctc
    16741 ttgaactata ttgttgctgc agtgctttta atttcggttg taattcttgc gttttacgca
    16801 tgctctttgt ttggaaatgc atcaacggca ataggatcac gcggatgatc agtgtaaata
    16861 aaatgatccc tatccctgca ttaccaaatg acaacgcctt gatcgcctca gcaaagtaat
    16921 aaacaatata acgatcccaa attcctgtac tctgtgcgct gacttcccca gttccgcaac
    16981 cggataagac gatgaccaaa ctaacgatac cggccatcaa aagtaaacgt ttgtatttct
    17041 tcacttactc ttttcctctc tgtcgattat ttttgcaagt tttaagacgt ggactaaatt
    17101 ggagcgaacc tcatcataag tcaacccctt cacacttggt ctagcaatca caataaaatc
    17161 caactccgga tcaatttctt cttttataga ataaactgct gctcggattt ttcgtttgac
    17221 ttcattgcgg tttaccgcgt tgccgacctt ttttcctaca gataaaccaa ctcgaaaatg
    17281 aggctgtccc ggtttttcca aacggtaaac gacgaatttg cggttagcaa aagaatctcc
    17341 cgtatggaac acggcttgaa actctcgttc tttttttact cgatacgctt ttctcattag
    17401 ttttctttcc ttttctatct ctcacttacg ctcataatca taccataatt acgattgtcc
    17461 tttcatcatt tccctaaaaa agagtataaa aaaaaccact gaaaccccag tggcctaagc
    17521 tgaaagaact tttcttcctt tgcgacgacg gctagctaac acacgacgtc catttttagt
    17581 actcatacgt ttacggaatc cgtgaacttt ttgacgttta cgtttatttg gttggtatgt
    17641 tcttttcata tattccacct ccaaaatgtt cttatctatt ttataaacac agacatactt
    17701 tgatagtata acgacaaagt agtgattttg tcaatataaa atagaagatc gattgttaaa
    17761 acttatccac aagattattt ttttctatgg gaatcctatg tggaaaaagt tatgcacagg
    17821 gattatccac agataataaa aggctggttt tacacagaaa acacacgtgt aaaaaaagta
    17881 atccacaatc aggcgatttc ctgtgtattc cgtctcctaa ctattggtat atctgtattt
    17941 tttatccaca gacgcaagag gaaatctatt ggtttttacg agttttccac ctgtgcatta
    18001 gtggtgtgga aaactttttt tgacaactgt gtttttctct tttttctttt tgtcgattgt
    18061 gtggataatt gtaattaaaa aatttttttc ttcggtttct gtggaaaact attgaaaaaa
    18121 atgctaaatt agtactagtt attcactttt taatgaagga ggaggcctta tatggtatcc
    18181 ctcgatgctt tatggaatga attaaaagca acataccaaa aggatttatc gcctgctagc
    18241 tataatacat ggatcgaaac agcgaaccct cgaacccttg atcaaaacca gctcgttgtt
    18301 gaggttccta gcaagattca taaagaatat tgggaaaaaa acctggcgac aaaaatcgtt
    18361 gaagtcggtt atatgttatc aggaaatgag attatccctc gctttattac tggcgaagaa
    18421 gcagagcaag aagaagttat agaagaaaaa aatccaaaag ttgtggcacc tagtccgcta
    18481 aaaaaagcca tgctgaaccc taaatatacc tttgatacgt ttgtcattgg taaaggaaac
    18541 cagatggctc atgcagcagc gctcgttgta gcagaagatc caggttctat ttataacccg
    18601 ctcttctttt atggaggcgt gggacttggt aagactcact tgatgcatgc aattggtcat
    18661 caaatgctgc aaagtcagcc taatgccaaa gtaaaatatg taagcagtga aacttttgct
    18721 aatgatttca tcaattcgat ccaaaacaaa acagcagaag agttccgtca agaatatcga
    18781 aatgttgatt tactgctagt ggatgacatt caattttttg cagaaaaaga agctacgcaa
    18841 gaagagtttt tccatacttt caatgccttg tacaatgaag ggaaacaaat cgtactaacc
    18901 agtgatcggt tgccaaacga gattccgaaa ctgcaagaac gccttgtttc tcgctttgca
    18961 tgggggctgt ctgttgatat tacaccgccg gatcttgaaa caagaacagc gattttacgt
    19021 aaaaaagcgg cggctgaacg tctagagatc ccagatgaca cactaagcta catcgcagga
    19081 caaattgatt ctaacattcg tgaattagaa ggtgcgcttg ttcgagtgca agcttttgct
    19141 gcgatgaata gtgaagatat ttcgactagt ctagctgcag acgcactgaa aacgttaaaa
    19201 tcaggaaaag gacatcctca attgtcaatc ctgcagatcc aagaagaagt ggcaaagtat
    19261 tatcacatcc aattgaaaga tctcaaagga aagaaacgcg tcaaatctat tgttgttcct
    19321 agacaaatcg ctatgtattt ggcacgtgag ctcacagata attctttacc gaaaatcgga
    19381 gctgaattcg gtggcaagga tcatacaacg gttatccatg ctcatgaaaa aatccagcag
    19441 ctgatggatt ctagtgtcag tatgcaaaat gaagtatcag aaatcaaaaa ctttttacta
    19501 aattaatttg tcgattctat caactgaaaa tagcatgtgg ataaaagaaa aaaacgttca
    19561 aaagttatac acactttttc cacagctgtt ttttcgtttc tctcttacgt tttttgagtt
    19621 ttccacagaa tcaacatgcc ctattacttt tattattctt tttaactaat aataaataaa
    19681 caaacattca aaggagatac atcatgaaag ttactttaaa ccgagctagc tttatgcagg
    19741 aattgcaaac tgttcaacga gctatttcaa gcaaaaccac gatccctatt ttgacaggtg
    19801 taaaaatcac actgacacaa gaaggtttga ctttgacggg gagcaacgct gatatatcaa
    19861 ttgaaacttt tttgtctgtt gaaaacgaaa aagcaaatat gcaaatcgaa tctactggtt
    19921 ccattgtttt acaagcacgt ttctttagcg aaatcattcg gagacttcct gaagaaacat
    19981 ttactttaga agttttagaa aataaacaag tagcgatcac ttctggaaaa gcgaatttta
    20041 tcgtaaatgg attagatgca gataactatc ctcatcttcc tgttgtcgaa agccataacc
    20101 agatgaaatt acctgtacac gtattgacta aactaatcaa cgaaacagtt tttgctgtct
    20161 cacaacatga gagtcgtcca atcttgacag gtgtgcattt cattttatct gataattctt
    20221 tattagctgt agctactgat tctcaccgtc taagtcaacg cgtgattcca gtagaacaag
    20281 cggctgatca ttttgatatt gttattcctg gaaaaagttt gatcgaatta tctcgctcat
    20341 taacaaatga agaagaaatc gtcgaaatca gcattatgga aaaccaagtg ttgttcaaaa
    20401 cagaaacgat gtatttctat tcccgtttgc tagaaggaaa ctatccagat accaatcgtt
    20461 tgattccttc aagttttaat acagaggttg aattttctgt tcctagcttt ttagcggcga
    20521 tcgaacgggc ttctttactt tctcatgaag gccgtaacaa catcgttcgt ttatctattc
    20581 gtccagatgc ggttgtttta tacggaaatt cgccagaaat cgggaaagta gaagaaagct
    20641 tgagttatac agcaagcagt ggcgatccat tagatatttc tttcaatccg gattatatga
    20701 aagcagcgtt gcgtgcattt ggagatatga gcatcaaagt gaaatttatc tctgctattc
    20761 gtccatttac attggaacca acggaagatg gcgttcaatt tattcagctg attactcctg
    20821 tacgtacaaa ttaacaatga ttttcaatgt tcttgaaaat ttaattgaaa agaaatagaa
    20881 aaaataaaat tttaaacaga aggccctaaa atctctttta aggctttctg tttatttttg
    20941 tttaaatcac cttttttaga ttaaatcgtc ttatatggaa aaatatatgg ataaatttgt
    21001 tttattgcga aaaaaaaggt ataatagagt atacttttaa taatgaaaat gagggatggg
    21061 cattgaaaca acaagtcatt ctaaatacgg aattcatgac gttgggccaa atgttgaaag
    21121 aagtcacagt tatcggtagt ggcggacaag caaaatggta tttggcagaa aacactgtgt
    21181 tagtcgatgg cgaaccagaa aatcgtcgtg gacgcaaact ttatcccggc atgatggttg
    21241 aagttccaga agtaggaact ttttttatgg taaaaaaagg aaacgacgat aatgaggctg
    21301 aataagctgt atttaaaaaa ttatcgaaat tacgaagagc tgaacatcga attttccaag
    21361 aacctcgtca tctttttagg agaaaatgcg caaggaaaaa cgaatctttt ggaaagtatc
    21421 tacgtattag ctatgacgcg aagtcatcgg acaagtagtg agcaggaatt gattggctgg
    21481 actgacgatc aggcgatgat tcaaggagag atcacaaaag gttcatccac tcttccatta
    21541 gaaatcttat tatctaaaaa aggccgaaaa accaagatca accatatcga acagaaaaag
    21601 ttaagtactt acgtgggaca aatgaatgtc attttatttg caccagaaga tctttcttta
    21661 gtaaaaggca gcccgcagat caggcggaag tttttagata tggaattagg ccagatcaat
    21721 ccaatctatc tttatgatct tgtccaatac caagcaattt tgaaacaaag aaaccagtac
    21781 ttgaagcaat tgaatgaaaa aaaacaaact gatttgcttt atttggatat tttgtccgaa
    21841 caactagcag cgtttggcag caaagtattg aaagcaagag cacagttcgt caagcgattg
    21901 gagttttggg ctaattcttt gcatcagcaa atcacccatc aaaaagagca gctggaaatc
    21961 gagtatctca ccgcagtcga ttctttagaa acacatacgc aagagcaaat ccaagaacaa
    22021 tttctcgcac ttttgaacca aaataaaaag aaagaccttt ttcggggaac aacgacagtt
    22081 ggtcctcatc gtgacgatct ttcctttttt attaatcaga aaaatgtgca gacttatgga
    22141 tcgcaaggac agcaaagaac aactgcacta agtgtcaaat tagcagaaat cgatttgatt
    22201 aaagaagaga caggggaata tccaatcctt ttgttagatg atgtgatgag cgagctggat
    22261 gataatcgtc aactccatct gctagaaaca atcgaaggaa aagttcaaac gttcttaaca
    22321 acaacgacac ttgaccatgt aaaaaataaa atgactgttg aacctgagat tttttatgtt
    22381 caacaaggga aactaaaagg agaagaaact gaatgacaga agaaagaagt ttagtagaac
    22441 gcgctaaaga gtatgatgcc agtcagattc aagtacttga aggacttgaa gccgttcgta
    22501 aacgacctgg catgtatatc ggttcgacta gttctgaggg tctgcatcac cttgtttggg
    22561 aaattgtcga taattcgatc gatgaagtat tagcaggttt tgcaacgaaa atccatgtga
    22621 ttattgaaaa agacaacagt atcaccgtta ttgacgacgg tcgggggata cctgtagata
    22681 tccaggcaaa aactggacgt cctgcagttg aaacggtctt tactgtttta catgctggag
    22741 gaaaattcgg cggtggtggg tacaaagttt ctggtggact tcacggagta ggatcttctg
    22801 ttgtaaacgc gctttctaca cagcttgatg tcaaagtata caaagaagga aatgtgtact
    22861 atcaagaata tcgtcgtgga gctgtagtgg acgacttaaa gattatcgaa caaacggatc
    22921 gccatggaac aacggttcac tttacgccag accctgaaat ttttacagag acaactgagt
    22981 ttgatttttc aaaattggct acccggatcc gtgaacttgc tttcttgaac cgcgggatgc
    23041 gtatatcgat tgaagacaaa cgagaagaag aaccagtcat caatgaatac cattatgacg
    23101 gcgggatcaa aagttatgtc gaatacttga atgcaaacaa aaccgtgatt tttccagaac
    23161 ctgtatattt ggaaggtgaa cagcaagata tcgcagttga agtctctatg caatatacag
    23221 acggctacca ttccaatatc atgagttttg ccaacaatat ccatacgtat gaaggtggaa
    23281 cacatgaatc aggattcaag actgctttaa ctcgtgtgat aaatgattat gcccgaaaac
    23341 aaaagctgat gaaagaaaat gacgacaact tgaccggtga agacgtgcga gaaggattga
    23401 cagctgttat ttctatcaag catcctgacc ctcaattcga aggacaaaca aaaacaaaat
    23461 tgggcaattc cgaagtacgg acagtcactg atcggttatt tagcgaacat ttcatgaaat
    23521 tcttgctgga aaacccaagt gtgggccggc aaattgttga aaaaggatta ctagcttcca
    23581 gagctcgtct agcagcgaaa cgtgcgcgtg aagtaacgag acgtaaaggt gctttagaga
    23641 ttagtaatct gccaggaaaa ttagcggact gctctagcaa cgatcctgaa aaatgcgaat
    23701 tgttcatcgt cgaaggagat tcggccggcg gatcagctaa gcaaggtcgt aatcgagagt
    23761 ttcaagccat cttgcctatt cgtgggaaaa tcttgaatgt tgaaaaagca agcatggaca
    23821 agatcttggc aaatgaagag atccggtctt tatttactgc tatgggtaca gggtttggag
    23881 aagattttga tgtatcgaaa gctcgctacc acaaattagt tatcatgact gatgccgatg
    23941 tcgacggcgc gcatatccgt acattgctgc tgactctttt ttatcgttac atgcgtccta
    24001 ttgttgaagc tggatacgtc tatattgctc agccaccttt atacggggta aaacaaggga
    24061 agaatattac gtatgtacaa ccaggaaaaa atgcagaaga agagttgaaa caagtcgttg
    24121 cttcacttcc tgcctcacca aaaccaagcg ttcagcgtta taaaggactt ggagaaatgg
    24181 atgatcatca actatgggaa acaactatgg acccaagcaa tcggatgatg gcccgcgtca
    24241 gtgtggacga tgctattgca gcagatcaga tatttgaaat gttgatgggg gatcgagtag
    24301 aaccccgtcg tgcattcatc gaggaaaatg cacactatgt gaagaactta gatatttaat
    24361 catgaaggag gaaaaagaat gagtgaagaa atcagagaaa acatccatga tgtcaatcta
    24421 accagcgaaa tgaaagactc cttcatcgat tatgcgatga gtgttattgt cgcacgtgca
    24481 cttcctgatg tcagagatgg tctgaaaccc gttcatcgcc gtattttata cggcatgaac
    24541 gaattaggtg taacaccgga taaagcccat aaaaaatctg ccagaatcgt cggagatgtc
    24601 atgggtaaat accatcctca tggagacatt gcgatctatg agtcaatggt acggatggca
    24661 cagccattca gctaccgtta tatgctagtg gatggtcatg gaaactttgg ttctgttgac
    24721 ggtgacggtg ccgccgctat gcgttatacc gaagcacgga tgagcaaaat cgctacagaa
    24781 atgctgcgtg atatcaataa gaacactgtt gatttccaaa gcaactatga tgatacagaa
    24841 aaagaaccag ttgtactacc tgctcgcttc ccgaatcttt tagtgaacgg aacaacgggg
    24901 atcgccgtag gtatggccac gaatatccca cctcataact tgtctgaggt agtagcggct
    24961 atcgatttgc tgatggataa tcctgatgtg acgaccaatg aattgatgga agtattacct
    25021 ggaccagatt ttccaacagg tggtttggtt atggggaaat caggaatccg aagagcgtat
    25081 gaaacaggta agggttctat taccgtacgt gcaaaagttg agattactga gatgccaaat
    25141 ggtaaagaac ggatcatcgt gacagaattg ccttatatgg tcaataaagc aaaattgatc
    25201 gaacggattt ctgaactgca cagagacaag cgtatcgaag ggatcacaga tttgcgggac
    25261 gaatcttccc gtgaaggtat gcggatcgtc attgacatcc gtcgtgacgc cagcgcatcc
    25321 gttatcttga ataacttata taaattgaca tccttgcaaa attcatttgg attcaatatg
    25381 ttggcgatcg aaaaaggtgt gccgaaagtt ttgagcttga aacaaatcct tgaaaactat
    25441 atcgaacatc aacgcgaagt catcacacga cggacggtct ttgaaaaaga aaaagcagaa
    25501 gcaagagcac acatcttaga aggtttgcgt attgctttgg atcatatcga tgaaatcatt
    25561 gcgattatcc gcgggtctaa atcagatgac gaggcaaaag caacaatgat cgaacggttc
    25621 gatttatccg atcgccagtc tcaagctatt ttagatatgc gtttacgccg attgaccggt
    25681 ttggaacggg aaaaaatcga aaatgaatac caagaactct taaaactgat tgaagattta
    25741 actgacattc tggcaagacc agaacgtgtt acagaaatca tcaagaatga attagcagac
    25801 ttgaatcaac gatttggtga taaacgacgc acagaattac tagtcggtga ggtcttaagt
    25861 ctggaagatg aagatttaat cgaagaagaa gaaatcgtta ttacattgac aaacaatggt
    25921 tacatcaaac gtttggcaaa taatgaattc agagctcaac gaaggggtgg acgtggtgtc
    25981 caaggaatgg gtatccacaa tgacgacttc gtcaaaaatc tggtttcttg ttctacccat
    26041 gatacattgt tattctttac gaataacgga aaagtgtatc gggcaaaagg atacgaaatt
    26101 ccagaatacg ggcgtacagc caaaggaatc ccaatcatca atttactagg tatcgattcg
    26161 agtgaaagca tccaggcaat cattgcggtg acgggagaag cagaagaagg ccactatctc
    26221 ttctttacga cgcgtcaagg tacagtaaaa cgtacttctg tcactgcttt tgctaacatc
    26281 cgaagtaatg gtctgatcgc aattggtttg aaagaagacg atgagctcgt caatgtgcta
    26341 ctgacagatg gtcaatctaa tatcattatt ggaacacata acggctactc tgtcactttc
    26401 aaagaagaag cagtccgcga tatgggacgt acagcttccg gggtcagagg gatacgcctg
    26461 cgtgaggaag attatgtcgt tggggcagcc ttaatgaagg aaaatcaaga agtattagtg
    26521 atcacagaaa aaggttacgg aaaacggaca aaagtatcgg aatatccagt gaaaggccgc
    26581 ggaggtaaag ggatcaaaac ggcgaacatc actgaaaaaa atggtccact agctggattg
    26641 accactgttt ctggagatga agacatcatg ctgattacag ataaaggtgt cattatccgt
    26701 ttcaacgtat cgactgtttc tcaaactgga cgttcaacat taggcgtacg tttgatgaag
    26761 atggaagctg atacgaaagt tgtcacgatg gcagcagtcg aaccagaagc tgcagaacaa
    26821 acagttgaag aacaaggatc agaagaataa ccatcaagac taagtgtgta agctagcaag
    26881 aataaccgat taaaaaatct ggttattcct gctggctttt ttgattagtt gaatttctct
    26941 taaaatattc gaaactgttc attctgtatt gcttttgacc aaaatagagt gtataattag
    27001 agcttgtgag tagtctaatt aattagataa ctctccttgc tcttaggaac ctaagagccg
    27061 aaagtccaca gggaggtgaa tatcaatgga aaacacgaaa tatgaaatca tgtacattat
    27121 tcgtccaaac attgatgaag aagcaaaaac tgctttaatc gaacgtttcg atgcaatctt
    27181 gaaagataac ggagcagaag ttatcgaatc aaaagattgg gaaaaacgcc gtttcgctta
    27241 tgaaatgaac ggttaccgtg aaggtatcta tcacatcgtt aaagtatctt ctccatcatc
    27301 agcaaatgct gtcaatgaat ttgaccgtct tgctaaaatc aacgacgata tcattcgtca
    27361 catgattgtt aaagaagaag cttaattgtt gtttcatgtg aaacaataga aaacgatgag
    27421 aggagatgac tattttgatt aataatgttg tattagttgg acgtctgacg aaagatccag
    27481 atttgcgtta cacagcaagt ggtacggcag tcgcaacatt tactttggct gtgaatcgta
    27541 attttacaaa ccaaagcggc aatcgcgagg ctgattttat caactgtgtg atttggcgca
    27601 aatcagcaga aactttagca aactatgctc gtaaaggaac acttttaggt gttactggac
    27661 gtatccaaac tcgttcttat gataatcagc aaggacaacg tgtatacgtg acagaagtag
    27721 tagctgacaa cttccaattg ctggaaagtc gttctgcatc tgaaaatcgc caacaaagcg
    27781 gcggattcca aagttctggt caatcagctg gcggatttgg cggaaacaat aactctaatc
    27841 aaacatctca atcatccaac ggtatgcctg atttcgaccg tgatacttct gacccattcg
    27901 gctcaagttc aacgatcgac atttcagacg atgatttacc attctaaacg aatttgatag
    27961 gagggaaata gaatggcaca acaaagaaga ggcggacgta aacgtcgtaa agtagactac
    28021 attgctgcta accatattga atatatcgat tataaagata tcgaattact aaaaagattt
    28081 atttcagaac gcggtaaaat cttgccacgt cgtgtaactg gtacaggcgc taaaaaccaa
    28141 cgtaaaatta ctgttgcaat caaacgcgct cgtatcatgg gcttgctacc tttcgttagc
    28201 gaagactaat aaatcctagg aattgaatga ctgatccttt tgatcagcta ttcaattcct
    28261 ttttttctgt aaaaataacc tctattcgtt tagtcgctcg aatgacgaaa gttatggtaa
    28321 aatcaaatta gtcatatatg ggaggaaaat tatggaaaat aaaaacaatc atttatcccc
    28381 gaaacctctc ttccttatcc tgtttatatt aatcgaagta ttggtagtct taattttacc
    28441 atttcgtttt gttagcgctt cggtcattct attgatgaat ttatggggtg ttcgctattg
    28501 gttgaaaatg aaacgttggc ttattttaaa taaacgtgaa aaaatccagc aggcttcgac
    28561 tgtagctgaa accaatctag cttatgtctc agaagtcatg cctgtaggag tgattgctta
    28621 tcagccatca agccaaaaaa tcgaatggct caatccatta gcattgaaaa tcaaagatca
    28681 aagtggatta acagaggaag aattgctaga tacttttttt actgcaaaag aaaaaaagaa
    28741 aaaccaagtc tatctagcag ataaaacatt tcagtttgat atggatacag taaagggtgt
    28801 tgtttatttt aatgatatta cccaaaacca gttgttaaaa ctccatcaga cgaacagtca
    28861 gccggtgatt ggtattttat ctattgataa ctatgcagat gccattgata aattagatga
    28921 caaagagatt tcttatttga actctttcgt cactacacta gtttctgact ggatgaatga
    28981 ataccatgtc tttttcaaaa gaatcaacgc agaacggttt ttcttcgtag cacagatgat
    29041 cgatctgaaa aagatgatgg ataaaaaatt tgatttgctg gatcgctttc gagcagaagc
    29101 tgaaaaacag agctcgccta tcacccttag tatggggatt gcttatggct caagaaccct
    29161 cgatgaaatc ggtggagaag ctcagaataa tttagatgtt gctttagtcc gtggaggcga
    29221 ccaagttgtc gtgaaagagg taaaagaagg agcaaaacct gtttattatg gggggaaatc
    29281 tgctaagaat gtcaaacgca cgcgtgttcg ttctcgagcg atgagtaccg ctttgcgtcg
    29341 gatttttgat gaaacaggcg atgtgtttat catggggcac aagtttccgg atatggatgc
    29401 tttaggctct gcttttggtg tcagttgtct ggcacgcttc aaccagaaaa aagcttacat
    29461 cgttatcaat gagaacgaga tcattccaga tgtagaacgg tgtcttgaag aaatccataa
    29521 gcatcctgaa ttagaaatgc aactaatctc tccagaacgt gccatagagc tgaaaaaaga
    29581 agaggacctc ctcgtgatgg tggattacca taaaccttct ctatcgatct ctcagggcct
    29641 atatgagcaa tttgataaga ttgtgatcat tgatcaccat cgtcgtgggg aagagtttcc
    29701 aagtaaacct ctgctgactt atattgaatc ttcagcttct tcagcttcag agctagtttc
    29761 tgagctgatc caataccaaa gcagcaaaac aaatcgctta gatcgttttg aggccacatt
    29821 attgcttgca gggatggttg tagatacaaa tagtttcaat gtccgtacaa ctgcacgaac
    29881 ttttgacgtt gccagctatt taaggtcttg tggagcagac gcatccttag tacaatattt
    29941 attgagctcg gatttagcga catacttgga gatcagcaat ttgattgctg gaagcgacta
    30001 tgtgacttct gatattgttg tggcggcagg gacagacgaa aaagagtata atagtgttat
    30061 agcagcaaaa acagcagata cattgctttc gatgatcaat atcaatgcag ctttcgtcat
    30121 tacaaagcgg acagacggct tgattgggat cagtgccaga agtaccggca cgatcaacgt
    30181 ccaaatcatc atggaatcct taggtggcgg aggacacttc acaaacgcag ctactcaact
    30241 ggaaaatacg acagttgagg aaacaaaaca gaagctattt gctgcaatca aagaaaatat
    30301 gaatcaaata tatgataagg agtaatccaa atgaaagtaa tttttttaca agatgtaaaa
    30361 ggaaaaggta aaaaagggga catcaaagaa gttccagcag gttatgcaca aaattatcta
    30421 atcaaaaata acttggcaaa agaagcaacg aaaagcagta tcagtcagtt agcaggacaa
    30481 aagaaagcac aagaaaaaca cgaagctgaa atcttggaag aagctaaaaa gttaaaagaa
    30541 ttcttggaaa aagaagatac tgtagtcgaa ttgaaggcga aagcagggga agacagccgt
    30601 ttgtttggtt cgatcccttc aaaacaaatt gctgaagggt taaacaaaca atacaaaatc
    30661 aaattagata aacgaaaaat cgaattagaa aatccgatcc gttcactagg ctacacaaac
    30721 gtacctgtta agcttcatca tgaggtgacg gctacgatca aagttcatgt cgtacaagaa
    30781 taacaaatct tgatagcgat gttcagctgg taagtataac cagaaggaaa aaagacaaac
    30841 cgaaatttat ctgagaaaac agctgcagca atgaaagcaa aagctgcaaa tcgatttcag
    30901 attgatttcg gtttcttttt tgggaacagc aaaatagcat aaagaaaacg agtataataa
    30961 aagagaacta tttttttatt acactttcgg tacgaatgat gacttttctc tcattttctt
    31021 gtaaaatgaa gcaattgaag acaaggagcg atacgtatga atgaagtgtg gcaggatcga
    31081 atcccaccgc aaaatattga agctgaacaa gcggttttag gctctgtttt tcttgacgca
    31141 gaaacgatca ttgatgccat ggagtacata gagccaaaag acttttatcg tcgtggccat
    31201 caaattattt ttgagacaat gatcgagtta aatgatcgta atgaagcgat tgacgtggtt
    31261 actgtcaaag accggctgga acaagccaat ttgttagaag atgccggtgg tttaagttat
    31321 ctctcagact tggcattagc agttccgaca gcagcaaata tcgtctacta tgcgaaaatc
    31381 gttgaagaaa aatcattgct gcgtacattg atccagacag caacaggaat cgttacgaaa
    31441 ggattcgagc aaggagaaga agttcaaaca attttagatg atgccgaacg cagtatcttg
    31501 gaggtttcgg aaaaaagaaa tcgaagcggc tttttatcta ttgctgaagt actgaactcc
    31561 acgattgaaa atatcgatcg actagctcaa aacaatgaag aaatcacagg tctaccaact
    31621 ggctatcaag gtctggataa aatgacagca ggtttccagc ccgaagaact aatcattctt
    31681 gctgcacgtc cagcggtagg taaaacagcg tttgcattga atattgctca aaatgtagga
    31741 acaaaaacag atcgttctgt tgcgatattt agtttggaaa tgggggcaga atctcttgta
    31801 aatcggatgc tttgtgcaga aggttcgatt gaggccagcc atttacgtac aggtcagctt
    31861 tcggaagaag aatggtcgaa tctgatcgtt gcgatgggga gtctttctcg agcaaatatt
    31921 tttatcgatg atacaccagg gatcaaaatc tctgaaatcc gtgcgaaatg tcggaaacta
    31981 gcgcaagaaa aaggcaatct aggcttgata ttgatcgatt atttgcagtt gattgaaggt
    32041 aacggtaaag agaaccgtca acaagaagta tcagatatct ctcgccaact gaaaaaactg
    32101 gcgaaagagc tgaaagtacc tgtcattgct ctttcacagt tatctcgtgg agtagaacag
    32161 cgacaagaca aacgaccagt gctaagtgat attcgtgaat ccggatcaat tgaacaagat
    32221 gcggacatcg tagccttctt gtatcgagat gattattatg aaagagaagg cggagatgac
    32281 gatgatggaa acgagccaaa aaatgacaac gtcatcgaag tcatcatcga gaagaaccga
    32341 agcggtgcac gaggaacagt tgaactactg tttatcaaag aatacaataa gttttcgtcg
    32401 ctttcgccaa gagaagaatt ttaaagaaga ggttgtgagc cttgagcaat cccgagagct
    32461 ctcgtaagaa gatgcaagga gtaaccgcag gaacgactag agtacttaat ttaaacagat
    32521 ctccaaaggg attgtgacaa aagtcttgtc acagtccctt tttccgaata aacggtgttc
    32581 aatcagctga cccttggtat tagctcagca aacgtcaaaa tatgaggaac tattttgacg
    32641 tttgtttctc taatactcag gtcaaaacgc tgatcttacg acctcttttc cttaaacggt
    32701 gttctcctgc caactcctcg gtcacaagtc acaatatcat caaacatgag aagcagtttt
    32761 ttgaaattgc tccttgtgac tcagagttaa acggcaggct cacaacctct ttcttaaacg
    32821 gtgttcaaaa gcttgcatct gcggtaatac gcccaatcaa acgaaaaata tgagaagcta
    32881 tttttgtttg gctgttctta ttacttgatg caggacagct ttttcacaac ctctgattca
    32941 cggtgttcca aaagtagctt cttcgaaaaa taagtcgaaa tttcacaaaa atttgagaag
    33001 caattttcgt acattccttc ttatttcttg aagctgacca cttctgttac aacctctttt
    33061 ttaataacca ttctaaaaag ataaagttcg ttttttaagc gtttttataa aataaaaata
    33121 aaaatcattc gattttattt gaaatatgta tctattattg atacaatggt tcaggattaa
    33181 ataatataga acgaggtgtt cacatgtcat ctgtagtagt agtaggtacg caatggggcg
    33241 atgaagggaa aggaaaaatc acagactttc tcagtgaaaa tgctgaagtg attgcacggt
    33301 accaaggtgg cgacaatgca gggcacacaa ttaagtttaa cggtgtgact tataaactgc
    33361 atttgattcc ttctgggatt ttttataaag acaagatcag tgtgatcgga aacggcgttg
    33421 tagtcaatcc taaatcattg gttaaagaat tagcttattt acatgaaaaa ggtgtagaaa
    33481 caagtaattt gcgtatttct gaccgcgcgc acgtaatctt gccttatcat atcaaattgg
    33541 accaattaca agaagatgct aagggcgaaa ataagattgg tacaacgatt aaaggaatcg
    33601 gacctgccta tatggataaa gcagctcgtg taggtatccg tattgcagac ttattagata
    33661 aagaaatttt tgaagaacgt cttcgtttga atctagatga caaaaaccgt caatttgtaa
    33721 aaatgtttga ttcagaacca cttgattttg acgatatttt tgaagaatat tatgaatacg
    33781 gacaacaaat caaacaatac gtcacagata cttccgttat cttgaatgat gctttggatg
    33841 caggcaaacg cgtgttgttt gaaggcgcac aaggtgtaat gctggatatc gaccagggaa
    33901 cttatccttt tgttacttct tctaacccag tagccggtgg ggtaacaatc ggaagcggtg
    33961 tagggccttc aaaaatcaat aaagttgtcg gcgtctgcaa agcctatacg tcacgtgtcg
    34021 gtgatggacc atttccaact gaattatttg atgaaacagg agaacaaatc cgcgaagtag
    34081 gacgagaata cggtacgaca actggtcgtc cgcgtcgtgt aggctggttt gattctgtag
    34141 ttatgcgcca ttctaaacga gtttcaggta ttaccaacct atctttaaac tcgatcgatg
    34201 tattaagtgg attggaaaca gtaaaaattt gtacggctta tgaattagat ggcgaactaa
    34261 tctaccacta tccagcaagc ttgaaagagt tgaaccgctg caaaccaatc tatgaagaat
    34321 tgccaggctg gtcagaagac attacaggat gcaaaacact tgcagaactg ccagaaaacg
    34381 cacgtaacta tgtacgtcgt atctcagagc ttgttggtgt acgtatctca acattttctg
    34441 tcggacctga tagaacacaa acaaacatct tagaaagcgt ctgggcgcaa atctaaggat
    34501 aaaaacgacg actgaatcag gacgttctta ccagagcgag tcgaagtgtt tatctatacg
    34561 ataataataa cttgaagagg tagtgaaaga gacgtttagc cttattgccg ataggctgtc
    34621 tcttgaacac tgtttattca gaataaggga ctgtgacaaa aaccgtgtca cagtcccttt
    34681 ttccgaacaa acggtgttca aaagcttgca tctacggcac taagcccaat cagatgaaaa
    34741 atatggagtg ctatttttat ctgattgttc ttactgcttg atgcagagca gctttttcac
    34801 aacctctcca ctaaacggtg ttctcctgcc aactcctcgg tcacaagtca caatattcaa
    34861 caaacatgag aagctgtttt ttgaaattgt tccttgtgac tcggagctaa acggcaggct
    34921 cacaacctct tggtaaacgg tgttcaatca gctgaccctc ggtattagct caaaaaacgg
    34981 caaaatatga ggaactattt tttccgtttt tttctctaat actcaggtca aaacgctgat
    35041 ttcacaacct ctgattcacg gtgttccaga agtagcttct acggaaataa gccgaaattt
    35101 cacaaaaatt tgagaagcaa ttttcgtaaa ttccttctta tttcttgaag ctgaccactt
    35161 ctgtcacaac ctcttatttt gattagaact tgcgaaaata aaccggttaa agtgtgtcta
    35221 gcgcaagaga tttgctataa tagacgataa gggtaaaatg taacgagaag gggttgaaaa
    35281 atgtgtatca aattgtaaca gattcttgtt gtgatctgcc ataccatgta ttagcaaaag
    35341 aaaaagttga ttttttatca atgaatctcc aattgaatga tcaagagtta gtagatgacc
    35401 tcggaaagac attcaattat gaccgctaca tgaatcagct gaaaaatggt gcgatgccta
    35461 cgacatcaca aatcaatgtt ggccgatatt tagaattttt ccgttcttat gcggaaaaac
    35521 agattcctgt tttatatgtg gctttttcca gtggattaag cggctcttac agtagtgcgc
    35581 ttcaagcggt tgaattgctg aaggaagaat atgaagaccc tgagatctat gtttttgata
    35641 caaaagctgc aagtattggg gaagggcttt tagtattgga agctgtaaga ttgaaaaaag
    35701 aaggtaaaag catcgaagaa accctagagt ggctggaaag taattatttg aaagtccatt
    35761 catgggtaac agtagacgat ctgaaatatc tagaacgagg cggtaggatt tccaaagcaa
    35821 gtgctactct tggcagtcta ttgagtgtaa agcctattat tacggtggat aaagaaggaa
    35881 ggctgacgaa tgttgacaaa gttcgaggaa gaaacaagtc gatccagaca atcgtcaatg
    35941 agacggtaaa aacaatcgtt gcaccacttg atcaaatcgt ttatgtggct tacgctgggg
    36001 atctagagag cgcggagaag gcaaaacggc ttttggaaga gcagataaag atgaaagatg
    36061 tgaagcttta tcccttagga ccaacgatcg ccagtcacac aggctatggc tgtatcgcga
    36121 ttttttcgat gggaatcagt cgataaaagc agtaactcat tctgtaaaaa agcccagaaa
    36181 ttgattgtaa caaaaacagc gactcttaaa agatagatga gcatcctatc tcttagaggt
    36241 cgctgttttt ttatttttta agctaaatag gccattatgc ccataactcg ttcaattgtt
    36301 tttgaatatc tgcattttcc aaaaattcat catatgtcgt atcagctcga tcgatcacac
    36361 ctttatccga aacggcaatg atgcggtttg ccaatgtttg gataaattga tggtcatgtg
    36421 acgcaaataa gattgagcca gtaaatgcca tcaagccgtc attcaatgct gtgattgatt
    36481 ctaagtctaa atggttcgtt ggatcatcta atacaagtac gttagctttc gaaagcatca
    36541 tttttgaaag catgcaacgg actttctctc caccagataa aacattcact ggtttcaata
    36601 cttcttcacc agaaaacaac attcttccta agaagcttct taagaaggtg ttatcatctt
    36661 cttctttact tgcatattga cgcaaccagt ctaaaatcgt tagatcagta tcgaattctt
    36721 tcgttgtatc ctttggtaaa taagaattac ttgttgtcac accccaacgt actgttccag
    36781 tatctggcgt aatttcaccc atgataactt tgaatagcgt tgttgttgtt atatcatttt
    36841 ctgcgacgaa agcgaccttg tcttctttgc tcaaattaaa agatatatca tctaaaattt
    36901 tctttccatc aatcgttaca cttacatttt ctacctgcaa taagtcgttt ccaatctcac
    36961 gttcaggttt gaatccaacg aatggataac gtctagaaga aggttggata tcgtctaaag
    37021 taattttttc aagcattttt ttacgtgaag ttgcttgttt tgattttgat gcattcgcac
    37081 taaagcgggc aataaattct tggagttctt tgatttgttc ttcttttttg gcatttgcgt
    37141 ttgcttgaag tttagccgct agttgactag attccaacca aaaatcataa tttcctacat
    37201 aaagtttgat tttaccaaaa tctagatccg ccatatgtgt acatactttg ttcaaaaagt
    37261 gacggtcatg ggatacaacg atcacagtat tttcaaaatt gatcaaaaat tcttccagcc
    37321 aattgatcga ttggatatcc agaccgtttg ttggttcgtc tagcaaaaga acatcaggtt
    37381 taccaaatag tgtttgtgct aataacactt ttaccttttg tccaccagtt aattcactca
    37441 tttgctgatg gtgcaattct tcagggatgt tcagaccttg cagtaaaaca gctgcttctg
    37501 gttcagcttc ccatccatta agctcagcaa attctccttc taattcagct gctcgaatac
    37561 catcttcgtc agtgaaatcc tctttcatgt aaatcgcatc tttttctttc agcacttcat
    37621 acagacgctt gtgtcccatg atgactgttt caagtacagt atagtcttca tagtcgtaat
    37681 ggttctgttt caatacggcc atccgttcat ctggtcccat agtaacggaa cctgtggaag
    37741 gctgcagatc ccctgataac actttaagga acgttgattt acctgcacca tttgcaccaa
    37801 tcaagccata gcagtttccg ggggtaaatt taatattcac atcatcaaat agtttgcggt
    37861 ctgaaaagtg caaactcaca tcatttacag taatcaattt ttttcctcac ttttatcatt
    37921 attagttttg acaagtctta tagaattata taggggaaag gtaaaagatt caaggcaatc
    37981 gaacattctt tgtgtttcac gtgaaacaga atgaaaaaaa taaaaataaa agcggagcga
    38041 aaatagctac tataggattt attagtttgc aacagcataa tttttgacgt tatttataag
    38101 agggagtact ataaaactgt aaaagaaatg aaagaaggat tgaaaatgga tgaaaaaaga
    38161 accatcgact ggggctcatt gattttggga attttatttg tacttgtctc attgttatca
    38221 tttcaagacc ctgtcggaaa tttagttgca attgtagtag tctttgcgat ttttgccttt
    38281 attaaaggga tatttgaact gtttgtacgg aacagattaa aagagctaac aggatataaa
    38341 ggaaagatgc ccttaataat cgggatcatc gatattctag ttggcgtctt tttcttattc
    38401 aatattggtg caggagtcgc agcattgcct tttgtttttg cagtatggtt tattgctgat
    38461 tcagttttag cgttatttac tgctgacttg gcaagaggag taagtgaagg atattattgg
    38521 tttacgatca tcgtcaatat tttaggaatt ttattaggaa ttttcttatt gtttaatcca
    38581 atttcttctg cgttgacatt aagcttttta gttggattct attttatgtt atttggtatc
    38641 acacatatcg tctatgcatt tagataagta aaatcaaaca aataaaaaag ccggcttccg
    38701 attacagttt tactgttgta attggaagcc ggctttttta tcatggacaa atatgcacga
    38761 ggtgattttt aggtgtcgag acaaatttat gcaaaaatgt gagaagctat atacacaaat
    38821 tttatcttaa tactcgaagc atagcgcagt tgtcacaacc tcttttcata taattcattc
    38881 aatactggca aatcatggac ttcatatttt tctttgaatg cttggatttc ttcttcagaa
    38941 tattttcttg gatctaaatg cagatcttct actggcaatg ggcgcttgtt attgatcttc
    39001 acatcgatta ctacaggacg atctgatttt gcagctgcat caaaggcaaa tcgaagttgc
    39061 gagtattctg tgactgtaaa gctatttgcc ccgagcgctt ctccaacttt accgaaatct
    39121 gcatcttcta aaaatacacc aaatttcttt tgttccgtat cttcttgttc tgcttcgatg
    39181 aaaccaaaag aatcattcga aaagacaaca ttaataattg gaagctgata tttgacttgt
    39241 gtaatgatat cttgcatgac catagcaaac ccgccatcac cacttaaggt aaatacttgt
    39301 ttttctgggt agcttagttg tgcggcaatt cctcctggca caccattacc catagttgcg
    39361 aaccatccag atgtcgtatg tttttgttta ccgttcatat tcaataaacg aatagaatgg
    39421 atagtcgtgt taccgacatc tgtgacgaaa atcgcatcgt cttcagcaat acgattgatt
    39481 tctttataga cagcctctgg acgaatcggt tcttcctctc gatcttcaaa agatttcaac
    39541 caatttaccc atttttcttt attttcttga tttgctaggt accagctatc agcagggcga
    39601 gcatccccta actcgacaag tctttgcaaa gctgtgtttg catcaccgag gatcgacaaa
    39661 gatgtttcat ggcgtcgtcc aaattttgac gcatcgatat cgatttggat aaattcagca
    39721 gttggattaa aaaatgcacg tccaaatggg aagtcgctac cgacaaataa gatcagatcg
    39781 gcttctgcca atgcttcatt tccgggttta gtagcgacac gtccagcaaa accaagaaag
    39841 ttttcataat catcaggaat aattcctttt gctagaacgg aagcgacaac aggaactgaa
    39901 aaatgttctg agaattcttt gatttgcgga aatccgtttc gcgttccttg accaacataa
    39961 agaactggtt tttttgcttt ttcaagataa ggcaaagcag ctagcaaatc tttttcttct
    40021 ggtaatatca cacttgtttt gtgagtgtga gcggtggaga aaggttgttc gtcaatttct
    40081 tcaaaaccaa gatcaacagg gatagtcacg atagccacgc ctttatgctc ataggcggct
    40141 ttaatggctt catctactac atgcggaaga ctttgtggtg tcatgactgt acgattgtat
    40201 acgctaacat ctgcgaaaat aggattttca tttagttcct ggaaagagtt atagttcatg
    40261 gatgtagaag caacttgtcc taagaacgct actagaggca catggtccat ctgtgcatca
    40321 tacaaaccat tgatcaaatg tgtcgcacca ggtcctgcag agccgaagac agcgccgact
    40381 ttccccgtta attttgcatc tgcagcggct gcgagtgcgc cgacttcttc atgacgaact
    40441 tgaatgtagt tgatttcggt tttttcttga tatagcgcat ccataattga attgaaagat
    40501 cctccgggaa tgccgtaaat atggtcgata ccccagcttt caagaacttt taccattgcg
    40561 attcctgcat tgatttttga catggtgttt cactccttta gcaatgatga tacataaatt
    40621 ttttgtatct agagtataga actttttatc gaaaatccca actaattcgt cttttcacaa
    40681 aaatgtagtc atgtttttgg gaatatgcta gagtagtaca tagatagatt caagagaggg
    40741 gaatggcatg gttgaatggc tattgagact tgaaccttgg cagcaagcac ttgctgggac
    40801 agcttttact tattttatga cagctcttgg tgccgggttg gtttttttct ttaaagaaat
    40861 caaaaaagaa gtgctaaact tgatgttagg atttgcttct ggtgtcatga ttgctgcaag
    40921 tttttggtct ttgttagatc cggctattac aaaagcagaa gaaaatggag atattgcttg
    40981 gctagttgta agtattgggt ttggtttagg cggtgtgttt ttatatatgg cagataaaac
    41041 actgccccat atgcattttg gaccacaaca tgaagcagaa ggattgccta cccatttaaa
    41101 acggacgatc ttgcttgttt tttctattac attgcataac attcctgaag gtttagccgt
    41161 gggggtagca ttcggtgcag cagcaactgc ggataatccg acagccgcta tattagccgc
    41221 tgtttcggtg gcgctaggta ttggtatcca aaacttccca gaaggagcag ctgtatcaat
    41281 cccgttgcga caagaaggtc tgagtcgtaa aaaggccttt gtttacggac aagcttctgg
    41341 aatcgttgaa ccaattgctg gagtgattgg agcgctacta gtaacgaaag tggagctgct
    41401 gcttccttat gcacttgctt ttgccgcagg agcaatgatt tatgtcgtgg tggaagaatt
    41461 gatccctgaa gcacagcaga cattgtccag caaacgtcat tttgcagttt ttggcgtcat
    41521 gagtggattt atcattatga tgattttgga tgtggcatta ggataaataa aaaaaatata
    41581 tatgatatat caaatagggc cgcgaactta tatcgcgacc ctattttttt agtaagttat
    41641 atcataatga agtgaatggt atcatacatt aataatagtt ttttctatgt gtatttcctt
    41701 tgatccagcg aacaagccag atgataagtg cgattgggat tagaactttg accgcaaacc
    41761 ataaaagccc gcttaggaca ctgacaaaaa gactgatgac gaagctagct gcaattagca
    41821 ctaaaagaac catgaagata tttaagaaca tatttttttg acgcatacaa aaccctcctc
    41881 ttgttcattc tttactatag aaaaagtata acagggattg tttaaaaaca cctccaactg
    41941 aagactgatt tttacttcat ctacttaaat gatcaaacaa ttgctttttc tctggtttat
    42001 catctaaaat agagcggaaa aggaggagaa tatcatgcct aaaaatcgtc ttgaagcatt
    42061 tacagatgct gtaatcgcga ttatcatgac tattttagtt ttagaacttc atgaacctaa
    42121 cggagacacg tgggaggcgc tcgctgcatt aggttaccga ttttttatct atattgtcag
    42181 ttttatcatt ttagcgattt attggaacaa tcatcatcat ttatttcaag ttgtacataa
    42241 gataaatgga cgggtcttat gggcgaacag tttctttgtt tttgcgcttt cgctttttcc
    42301 gtttgcaact tcatggatca gtgagtacat caatagcctg gctccagaaa tgacttatgg
    42361 ttttgttacc ttgaccgcta atattgcgta ttatatcttg gcaaaagaac ttgtcaaagc
    42421 aaataaaggc cacgagaaag cattgaaggc gatgttgaat aattacaaga aatcgtatct
    42481 atcgattggt ttgaatgtgt taggaattgt cttagggtat ttagtagcgc cagtagccgt
    42541 gctgatcgca aacatcgtga ttctagctgc ttggatcatc ccaagtcgta ccatcgaatc
    42601 acaatatcgg taaaatgatc cgtgtttaaa atttaagaga aaaatataga aaaaataaat
    42661 aaacgatcaa atatccgagt gatactagta ttcaaagagg gatgcagatg gatcaaaaaa
    42721 gaattcatgt aggactgatt actagttttg tcacgatgct tatttatttg gatcaaggtc
    42781 atttgacttg gacagtagtt ggtgtcgtag gatttttgac attattcaca gcaataaaaa
    42841 aataaacatc tttatgtaat ctgatgttct atctatttaa gaaaagcatg tttacagcag
    42901 tatgattctg ttgtaaacgt gtttttattt gtggaaaatt taatttttag aaaagtgtat
    42961 cgaaaaatag atagttagtt tttccacagt ggataacttc gtaagagata aaaataaaaa
    43021 attagtcaaa gaagggcgta tagatttctt ttgataggag atatacaaca gaaatgaata
    43081 aatattaacg tgttttcaaa cagtataaaa cggtgtggtt tttggaataa aaaaataaca
    43141 tatctcattt tacacttttg ttattttata cttaaaaaat aacgacacag aaaataccgt
    43201 gtctcagatt tctctactac ttctaaaaac tactgttttt ttcctttgaa atgccttcaa
    43261 aaagtaggat caggcagaat atactggcag aatcaaggag aagggagcct aaataaggag
    43321 aaaaaccata gaaaatataa agtaattact tataaaacaa gctttttata gaaaaataat
    43381 atacctgagt agggtataaa ttaagacgga attcctttct agattgagat attgactagg
    43441 aagaatgtta agattttaag cctttaagct aaaaaaaaac cctttttgtt aaataagggg
    43501 aatatagcct gtcagtttca aactgcaagt cgtcctgctg caataatata gtagattaga
    43561 gatgaaaata gattttttta aaccaatgac tgaataaaaa gaccgtcata gatacacatt
    43621 ggaatgtgtc tattacggtc tttttttacg aacgatttta ttgaagacgg acagttcggg
    43681 tcaaaaataa aaaagctacg atcagaaata agaataaaat gtatcccaaa ataatggcta
    43741 gacggtctaa cttatttgtc gatagatgtt tgtttagaag ttgataggcc cataaaccta
    43801 tcagtcctcc tgttgtatta gttatcaaat cagtgatgtc cgctacgcca ataccgaata
    43861 ggaattgaat caattctgcc aagaagctta caaggaaaat aatccctaat tttttagaaa
    43921 aagaaagtct cttgaaattg acattcaaaa gcaccccaaa aggaaaaaag acaatcaagt
    43981 tataagtggt ctcacgtaat accgtcgtat tttcaaaaga aaaagtagaa aaagggacga
    44041 gattgacatt gctgtaagaa taagtgagaa attgtggaag attaaatgat agcttgaata
    44101 aaatcaacca taatagaaag aataaataaa tccctaataa aaattttgat acataccgca
    44161 tagacatctc ctccatttaa aaagtatacc atcgaaaacc gctgaaaaat cataaaaaag
    44221 tatgaagttt aaggaccaac gtagttatcg tacgaaaatt agaagctttt ttttgttggg
    44281 aatccggttt ctttaacaaa gctaagatag cgagttgctt ggaaaagttg ctatcttttt
    44341 tctgtcaaaa cgactcggaa tgttcgtttt ttgttctaat ttctccaagt tgtttacttt
    44401 ttgatactaa gtttatgaaa aatcaagaaa tagttgttat actaggtaat gctgacaaac
    44461 gggattggca tttcatcttg gttcagcttt ttttccaatt actaggaagg agggatagat
    44521 tgttcaagac ttattttcgt ttcaataaaa tacaagataa tccttttcgt atcatgaatc
    44581 tgatgctact tatctttatt gtattatggt taggttacat aaatcatgat tttttgattt
    44641 caagtttttc atcattaggg atctttactt ttttctatta tcaaaacata ccgatgaaat
    44701 atttgctgaa acgtatgttt ctgatcggtt gcggactgtt ggttgctttc gttttgggga
    44761 tcttatcgac ttatgtttta tggcttgaac catttgccgt agctttggtt gctttttcca
    44821 gcagattcgt gttgcgatta ttccatattt ctaaaccagg tggcttgttt tttgcgatgc
    44881 tttctgccat gggaacgagc atgcagctgc caatcgctca attaccgatc gtctcacttt
    44941 atttttttat gggtgtcgtt tttgccctga ttgcggcagt gattacaaaa ttactggatt
    45001 cacggcctga gcagacaatt gaaaaagcaa ctttaaaaga aagatttcac gaagagcctt
    45061 tagtgatcat tgattctgtt ttctacagcg ctgccttatt tctttccgtt tatgtcagtc
    45121 acggcttgaa tctgcataat ccttattggt tgaccttgtc atgtgcatcg attttgctag
    45181 cagaaaactt ggatgcgatg aagcatcgac aagtccaata tctgattgga tcgatgggtg
    45241 ggttatgtgt gtcggcattc ttgtcatttg tgccgtttac gcagttgcag accatttttc
    45301 tgatcacttt tctatatgga atcgcacaat ttctagttgc tagaaattat gcagttgcta
    45361 atatttttct taatccgatg gcgttgatgc tatctacact tattcgtgga gcatacttga
    45421 tttctttgat cgaatatcgt tttttaggga tcgtcatagg aagtttcatc ggtttaggtg
    45481 ttgcgtgggt aatgacggtt ggtttgcaac attatttaac ggttgttcgt caaaaattag
    45541 aatagaagga caaatatatg tgccaaaaga ggttatgaca agatttttgt cacaacctct
    45601 aattcaaggt gttcaaaagc cagattctca gcattaagtc aaattcacac aaaaatgtgg
    45661 aaaggaactt tcaaaaaaat tttatattta ttctatcaaa aaattttgtt tatgatggta
    45721 actgaataaa ctttcctgag atggtcaatg ctttccttga aagtcttaca gatattcttt
    45781 cttcatagaa agtttaagtt ttatagttag tgtacaataa aagtatgttt ataccatatg
    45841 gtgtccggat aatcagtcat ttaaacaatg aggttcaaag atatgaaaag gggaaatttg
    45901 atgaagaaaa taagcaatga aatccaaatt ctggcagaaa ctttaactct tcccaaagtc
    45961 gttatagagc aaatgattgt acaagcaaaa aacatccttg atgaggtgtt tgagcaatat
    46021 agtcatgaac taatggatcc taataaagca aaggcgactg caaagaaaat agacaaagtc
    46081 tatgaagagg aaccttttgc agcattagct atttatctat atgcagcttc tcaaagttgg
    46141 aaaaaaattt atcaaccatt gaagattcca agaactatct atttggcaac aatgaatgct
    46201 tttactagat ttattcatga acatttccaa gtaacaggaa gctatcgctt tgaccgtggt
    46261 ttttggattt ggcattacac tagtggcttg atctttcgga ttggtgaatt ggagtacgaa
    46321 atgacatatt ttccgaaagg gtacacggat ctaagattag aaggaaagca gtgcctttct
    46381 cttcatattc cttccgatgc agatttatct cagaataaga taagagatag ttacgaaagt
    46441 gccattcgtt tttttgaact ttattttcct gattaccatt accaagtgat gtacacagat
    46501 acttggttac tatcacccaa tcttactaaa tggttgaaaa aagagtcaaa aatctgtctt
    46561 tttgcagccg attatcgatt attatcagtt gatgaacagg acgatagtgg agtcccttgg
    46621 atctttggac gagtagatgc ccaaatacat gattatccag aaagtacgag tttacagcga
    46681 caagcaaaag agcaattgct tgcaggcgag cacattggct ctggcttagg tattcttact
    46741 tcataagttt agtacttcga aatagtttaa aagagcgtga gacaaaagta aagaacactt
    46801 ttgtctcacg ctctaaacac gtataaacgg cggaagcaga agcaactcct tcggaaataa
    46861 gctgaaattc acaaaaattt gaaaagcaat tttcgtgaat ttcttcttat ttcttggagt
    46921 taaacgcttc tgtcccagcc tcttttttag tgttctatcg aacacacagt acgttcaata
    46981 ggtaaactag ctataacaat agatattaaa gttaacggac aagagggcct tttttaggta
    47041 gctaaaacgt aataatgaaa atttatttcc agagatagga gtcaatcagc tagtctgatc
    47101 gactgtttta acaagttgac tttcatttta acttttgata ccatttaaaa cacaaatcgt
    47161 aattgtttcg atttgtgttt tttagcatga ctacaatcaa agaagaaagt gggtcgtcca
    47221 tatggaaaaa acagatatct caagtgcata ccgccgcttg aaaagcccaa atatcaaaac
    47281 acgaaaacgt gcgctgaaga tcatcaaaga tgtgaaacgg aatagtggga aaaggtaaga
    47341 agaaggaaac ttaattaaaa aaatagccga aaaacgtttt tcggctattt tcaataatcg
    47401 gtttttgtgt aaggtttccg aaagaactgc tgttgatttt ccatttttaa catatgataa
    47461 attggtagaa tctttctttt caaattgata ccattcccta attccagtta tatagttaac
    47521 tacagaacca caaagcacgt acgtttataa aagtattatc tgtagttatt tttcaattcc
    47581 ctttcaacct cttattttga ccagtagtat tgatcacttt accttttaac acctttgttc
    47641 gtttttgaaa catttttagt caagaatgga aacgtaacta cataatcaaa ggttttgcga
    47701 aatatttcat gaaatatttc atgtagaagc gagcaatacg gttgcaaata accattatcg
    47761 tttaataagc agttacgaaa gctcccaata tctctaacgt tcagctcact ccatttcttt
    47821 tcttcaaaaa aatcagtgat tcgtatctct ttctatttgt cgaaaaagtt aactttaaaa
    47881 agtaacgccg aaaaaatatg caaaaaaata aaaaagcagt tactattgct agaataacat
    47941 caaggaataa taagttttgg ttttcagata atagtcgata agttgtgtat tggaatttta
    48001 gatacagtaa taaagtattt ttcatgaaat tttgtgagaa tcactattac aagtatcttt
    48061 aataaaatta atggttaagg aggaacttaa agtagaatgt aaatgaatag ttgtagtcag
    48121 tcgattgtga tactagactc aaagttgcag gaataagttt ttcaatttgt gattggaaga
    48181 taaaaaatga aaaagaaggg ctttttttta tactttgttg attgtagtgt ttattttccc
    48241 tctgtttagc caagtaacat tttctatgac tcaaccagtt tcaagtgagg aacatgataa
    48301 cctttttcgt gctacagaag agtttaagaa atatcaggaa aatattgttc cggagactcc
    48361 attagctagt gagccaatta ctgatattga tggaaaccaa ataggatggt atatacagta
    48421 cgaagttatg gtggtaaata atgactcaat agtaaaaaat acagtaggct tagagctaac
    48481 accgattgaa aaggtgagtt cattgttaac gtatatttat actgatgaaa gtgacgagac
    48541 tgagatcatt ttaacggatt actcaaaaat tgctactgat aaaaagtata tattgtggat
    48601 gtagacacta gtgaaatact ttatgatata gaaattgatg aaaatttact agatgtagca
    48661 caagaaatcg atcatcaaaa gcaggaagct attcgatatg ctggtagaaa agggaaaaga
    48721 aaatatttat tacgtgaatg tagcaaaagt tagagaagat gaaaatgagt ggaaagaatt
    48781 caagagtcgc tactcaatta actcgactcc gacatttaca gtttacagag aaggatcgat
    48841 agaaaaaact gttttttgga ctaaagaaag tggaatgtct ttagctgaag tagaagagtt
    48901 tttggattat gttagtatgc aacagtaagg gagttcttat tatgaaaaat tttgacacat
    48961 attatgttat tgttttttcg atatctttgc tgttaatatt actaacttta atgcagtata
    49021 aagagtatcc agagtatttt attttaactt ttgtatattt agtaagtagc tacacacttc
    49081 tatataaatt cagaagttct tctagagttt ctaaagtttg tttcttaatt agcttattga
    49141 ttctataata tttttgattt atataggaaa ttaaaaatat tatagaatca acactcagag
    49201 aacgggttgg tttttaatag atttaataag tactgataat gaaatttctc ctggttggga
    49261 aaacgaagtt ggttaccctg tagaagaatt ttttcaagat tactttgcgg agtatgccga
    49321 taggataatg agagattacg taacagataa aactcaagaa gtcatcaatc aatcccagtc
    49381 attaaatgaa ttatctgata aggcgaaaga agaagcagtt gccattattt cttcagggat
    49441 tagtgactat attgatatga gtggtgaaat caattatggc gataaagaca aaattgtacg
    49501 catgataaaa gcttttatca aaacttttga tgtgaaggca gatcttaagt ttaatgatac
    49561 ttacctagta ggaaaattaa ttaatatcct tgggacagag aaagatacgg aaacgtttat
    49621 ttcctctttg tctatgttgt ttacagataa gcatttttca actcagcttg gtggagagga
    49681 actagtggaa atcttttaac cattacgccc agcattaata aaagtatatc aaaaaagtac
    49741 tcctgatgat ttttaagatt ggtttgagaa ataatgtgaa aacactattt ttaatgttaa
    49801 ttatagatag agatgaacgc gtcatatggt taaaagaatg aaaaagtcaa agatacactg
    49861 ctatatttca ctaaggatat agcagtgtat ctttcatgtc gtttcactgg cagtttttta
    49921 taaaaggagg tgtgcatttc agttgctttt ctttggtagt tagttgaatc gtttaagaat
    49981 taacggatgt ggcagacagg tgctctgtcc aaaaaccagt aaaatctttg atggttccat
    50041 ctttatttag ctgtgcctgt tcaaatactg ttttgttttt accgaatgga tcaattgcaa
    50101 taattgttcc gatccccgca cgtttggcag caagtaatcc tgagtaagca tcttcgataa
    50161 caagacaatc agccggagct aagctcagtt tgtctgccgc tttaagaaaa atatccggtt
    50221 gcggtttccc agggaaagag ccgtcgtcat agacaatctt gtcccagtca aaccagcggg
    50281 ctaaatcgaa aatatcaaaa taaaaagcaa cattctcttt gacagtagcc gtggcaatcg
    50341 ttaatggaat ctgttggtca gtcagctggt caagagtcgc ttcaagccct tttgtcaact
    50401 gaagctcgtt ttcattttgc aagcaaagca tacgataata gctttctttt tcttctgaca
    50461 atacggcgat ctcagaggcg gtcaaatgct ctgaaatgaa atgtttcaaa atctccgtat
    50521 tcgtccgacc atgaatattt tttaaaatat cctcgtctga taaaccatct tttgtatgat
    50581 catgtatcat atgcagccaa gcagcttcat gcagatgaga gtccaaaaac attgttccgt
    50641 tgaaatcaaa tataatccct ttcatagtta cgctcctata gtggtatttt cggttgaatc
    50701 agcaatttgc agatcgacat attgtgcata gtgctcttga acctcccgcg agatctggcg
    50761 atccgtaatg agcagatcga aatcatgcaa attataaaac acataaaaat catctcgatt
    50821 gaatttttta ttatcaacga gtagatattt cttacgggaa ttatttagag cgatctgctg
    50881 tgcttctcct tcttcggtac tgtaagtaga gatcgcttcg ttgtgaacgc catttgaact
    50941 gataaatgct tttgtaaact ttagtcttct taaattgtcg ttggtgatcg gtccgacaaa
    51001 tgcgccggta tttttccgga aatcaccgcc aatcagtaga atttctggtc catctgcttg
    51061 agcaagaata tcaaaaactg gataattatt tgtaatgatc cgaattttct tgttcagtaa
    51121 atgcgtcgcc aatagttcga ttgttgtacc tggtcctaag aaaatcgttt ctccctcgtg
    51181 aatcaaggag gctgctgtgg cagcaatttc ttttttttct tgaatctgca gagtggcttt
    51241 ttcagtgtga gaaagttctt gatctaaagt gtaggaaaga ctttgagccc ctccatggac
    51301 acgcagcagc ttgcccgatt tttctaattc atctaaatct ctgcgaacgg tcatatcaga
    51361 aacatctaat tgattgatga tttcattaac ggtaaggatt ccttttttat tgaccatttc
    51421 tacgatagta agcaatcttt cttttttcaa cattgtcttc acctctaatt taaggataat
    51481 ctatcatata aacggacaac agtcaatcta attcgaacaa aagtaaacat ttagggtggt
    51541 ttttatgttt gttacaatag attttattgc tgttttctgg tttttatgat tatttgtgtt
    51601 tgtttttgtt gacaaatgtt ttggatgcgt ttacaatgca atcagttaga aagagcgaaa
    51661 actgattata gatttgagga gagatgtaca tgcttaaatt accagaagat tttatttttg
    51721 gcggagccac agcagcctat caggttgaag gagccactaa ggaaggtggc aaaggcgctg
    51781 ttgcttggga tgacttttta gaggaacaag ggcgattcag tcccgatccg gcaagtgatt
    51841 tttatcatca atatgcaaag gacattgaat tgtgtgaacg ttttggtgta aatggtctaa
    51901 gattatccat tgcttggagc cgcatttttc ctgatggagc tgggaaacca aatccagaag
    51961 gaatcgcttt ttatcatcgt gtgttcgaag aatgtaagaa aagaaacgta acgccgtttg
    52021 tgacgttgca tcattttgat acccctaaac gtttgtttga ccatggagat tttttgaatc
    52081 gagaaacaat agaagcattt gtttcctatg ccattttttg ttttcatgaa ttcaaagaag
    52141 tcaaggtgtg gagtaccttt aatgaaatct atccagttgc aaccaatcaa tatttgttag
    52201 gtgttttccc accaggaatc aaatatgatt ttacaaagat cgtcgcctgt cttcataata
    52261 tgatggttgc tcatgcccgt gtagtgaact atttcaaaga aaacgaactt ccgggtgaaa
    52321 ttggtgtagt tcactcatta gagacgaaat atgcggcaac agacgcgccg gaagataagc
    52381 atgctgcctt tttagacgat gcattgtcga tccgtttctt attagatgct acctatttag
    52441 gctattattc aactgaaacc ttgactgctc ttgatgagat atgtgaagca aatcaggcca
    52501 gctatcattt tcctgaagaa gatttcgttg aattgaaaaa agcatccacg cgtaatgact
    52561 acttagggat caatcactac caatgccatt ttgtcaaagc ttacgatgga gaaaatgcaa
    52621 tccatcataa cggtacgggt gaaaaaggga cctctgttta taaagtgaag ggaatcggag
    52681 aacgtattta taaagaagga attcctcgaa ctgattggga ctggctgatt tatccagaag
    52741 gtctatatga cttgttgctg cgaattaaaa gcgattaccc acattacaac aaaatctata
    52801 tcactgagaa cgggatgggg tataaagatc agtttgaaga tggcattatt atggatcagc
    52861 cgagaatcga ctatttgaga gtctatttgg aatccttaag caaggcgata acagccgggg
    52921 taaatgtgaa ggggtatttt ttgtggtcgc ttatggatct tttctcatgg acaaatgggt
    52981 ataacaaaag gtatggcttg ttttatgttg attttgaaac ccagaagcgt tacccaaaag
    53041 aatcagctta ctggtacaag ttggtcagtg aaaccaaaac gattatttaa taagtgataa
    53101 tggaggaaga aaagatgaat aaagaggaat tacaaatgct tggttttgag atcgttgcat
    53161 attcaggcga cgctcgcagt acattattga aattattgaa agaagtaaga caaggaaact
    53221 ttgaacatgt tgattcggcg ttgaaagaag ccgacgaaaa tttaaccctt gcacataatt
    53281 cgcaaacaaa aattttagcg gaagaagcat ctgggaaaga gatggagatg ggattcattt
    53341 ttatccatgg gcaggatcat ttaatgacca ctttattgct gagagatctg attcaagact
    53401 ttattgtact gtacagacag aatcaaggat aggagaagaa cgctatggat ggaatcatta
    53461 aacaaatcga aaaagggaaa ccattttttg aaaaaatctc acgtaatagt tatttaggag
    53521 ccgttcgtga cggattttta acagcgatgc cagctatttt attttcaagc attttcattt
    53581 tgattgctgc ggttcctgag atttttggtt accaatggcc tgaatctgtc tccacatggc
    53641 tatggaaagt ctataattat tcgatgggtg ttgtagggtt actcgtttca gcaaccactg
    53701 ctcgctgctt ggctgattcg atgaatcgtc gcttaccgaa aaacaaagta atcaacacca
    53761 cctctgtgat gctggcctct gtggtaagtt tcctgttgtt aagcgtctct ccgattgaag
    53821 gtggattttc aacggaatat atggggacaa agggactact ggcttccttt gtcgctgcat
    53881 ttttaacagt taatttatat aagttttgtg tgctgaaaga tattaccatt aaaatgccta
    53941 aagaagttcc tggaacgatt tcgcaaacct tccgagatat ttttcctttc tctttttcag
    54001 tatttgcggc cgttttaatt gatttaggca ttcgacaaat cttccaaatc tcatttgcag
    54061 aagcaatcat tacggtgctg cagccgctat ttacagcagc tgacgggtac ttaggaatcg
    54121 ctattatctg gggagcgatg gcgctgtttt ggtttgtcgg tgttcatgga ccgtcgatcg
    54181 tggagccggc aattgcggca attatctatg ccaatgtgga aaccaatctg caattgttca
    54241 attccggtga acaagcttct aaagtactga cggtgggttt agggaatttt gtaggaacta
    54301 tgggaggaac tggggcaaca ttggttgttc cttttatctt cctactcttt gctaagtcta
    54361 agcagttgaa ggcagttggg aaagcttcct ttattccagt aagtttcgct gtcaacgaac
    54421 cattgctatt tgcggcaccc atgattttga acccttattt ttttattcca tttttgttaa
    54481 cacctgttgt aaacgtttgc ctgttcaagt tttttgtcga tgtattgggc atgaacagct
    54541 ttatgtacgt tttgccttgg gcaactccag caccgatcgg tttggttcta ggaacgggca
    54601 tgggtatctt agcttttgtt ctagcagcgg ttctaatcgt cgttgacttc ctgatctatc
    54661 taccattttg caaagcatac gatgctgtct tagtagagaa agaagcacaa aaagcagagg
    54721 tgatcgcaac cgaggaaggt gcttctgccg atgtacgtga ggaagtacct gtggcagcga
    54781 gtcaagttat cagcgatgca aataaagaaa tcaatgtgtt ggtactttgt gctggcgcag
    54841 ggacaagtgg gatgttagct aatgctttaa aaaaaggtgc atctgaatcg aaagcaccga
    54901 tcagtgcaat ggcgggtgct tatggttctc attacgaaat gctgcaggat tttgatatgg
    54961 tggtcttagc accgcaagtc aattcttact atgatgatat caaagaagac accgatcgct
    55021 taggaatcaa gctggttgcg acaaaaggag cagaatatat cggattaacg agagatcctg
    55081 aaaaagctgt tcagtttatt ctgaaccaat ttcaataaag gaggagccat aatgaaaatg
    55141 ggaatttggt tgcgtaaagc tgttttattt gcagctgtgt taggggcttt gggggctgtt
    55201 tcaaaaactg ttgaagcatc tgccagcgaa tttattcgcg gagcagatat ttcgatcctg
    55261 tcagatatgg aaaaatctgg tgcaaaatat tatgaagacg atatttcaaa agatgcctta
    55321 gagattttaa aaaataatgg tgtcaactat gttcgactgc gtttgtggca ggatccttat
    55381 aatagtaatg gagaaagtta tggagcaggg acaaatgatc tggaaacgac gattgacctt
    55441 gcaaaacgag caaaaaatct gggacttaag gtgctgctgg attttcacta cagtgatttt
    55501 tgggttgatc ctgggaaaca gaatcttcct aaagcatggc aaggtctgac ctttgaagaa
    55561 atgaatacgg cattgtacga ctatacaaag aacgttctgt cggaaatgaa gcagctggac
    55621 gtttatcctg atatggttca gatcggcaat gaactgaata gcggaatgct ctggccttat
    55681 ggcaagtctt ggggagaagg cgggggagaa tttgatcgat tggctgcttt tttgaagtct
    55741 ggtatccaag ctgttcgaga cactcaacct aaaacaactc cagtaatgct ccacttagct
    55801 gatggtggcg atacaggagc atttacttgg tggtttgatg aaatcacgag tcgaggtgtg
    55861 tcatttgatt taattggagt gtcgtattat ccgtattggc acggttcaat gaatgaactt
    55921 caaaccaata tgaatgcgat cagccaacgg tatggtaaag aagtgatcgt agttgaaaca
    55981 gcttatgggc atacaacagc gaatgccgat actatgccaa atgcttttgg tgaagccgaa
    56041 gcagctgcgg ggggatatga accaacaccg acaggacaag cagagtattt gctggatctt
    56101 gccgatcgga ttcaggcagt accgaataat cgcggggcgg gcttcttcta ttgggaacct
    56161 ctttggtaca acggaaatgt gagttgggca acacaagcag gtatgaatta tctcagtgtt
    56221 caatccacta tgggaaacga atgggacaac caagcgatgt ttgattttgc tggaaacgcc
    56281 ttgccaagct tgcgtgcgtt taaacaagca ggggcgcaaa taaatctagt taaaaatgca
    56341 agtttcgaaa gcgatggacc aacgaccagt ccttccaatt ggcaaacctg gtttcaacaa
    56401 ggaaccgcta agggtacgat caaaacggaa gcgggcactt tttttgggga ctacaaacta
    56461 actttttggc aggatcaagc atacgaggca tcagcttatc aaaatgttag tggcataagc
    56521 aaaggaactt acacattgag tgcctatgta atgtctgggg gagagtttga tactaatcag
    56581 ttatatatca aaaattatgg tggagcggaa ctaaatactg cggttgttaa aacaagtgaa
    56641 tggacaaaaa ttacaatcaa agacattcca attacaacag gtgtttgtga aattggggtt
    56701 tatagcaagg cttcaggaaa tgcttggacg aacgttgatt ttgtttcatt ggtgaaacaa
    56761 tagactgcgg atcgtttcga ttcaagatcg gaggttccct tcagccacat cgttagcgta
    56821 gaaggcagga atcgaacctg cacctcgcct ttgccaaaaa taaccagaaa cgatttccag
    56881 tcatttttac caaaacgagt aaagcaccag acttcatcta cactttgtat tatgctaaag
    56941 agagttcaac gatttcgtaa gaagcaatga aaaaattgca aaaagttgtg cagataacat
    57001 aaagtttgtt taagaaaggg taaccttaga attccgtcgt gaatatgatt tgagcactta
    57061 gatggataga aaaaagttct cggaaaacag ttcgtttttc gagaacttct ttttatgata
    57121 agaatgaaac aaattaactt atattatagt ctcttttggt agggaaccat cttattttta
    57181 atgaaaatca agcattttag ctattgaaga atgttgattt atagggattc cccctccata
    57241 ttatgttggc tctttattcc cactccactg ttgctggtgg tttagaagtg atgtcataca
    57301 cgatacggtt gacgtgggct acttcgttta cgatacgtac agagattttt tgcaagactt
    57361 cccatgggat acgggcaaag tcagcggtca ttccgtcgat tgaagttaca gcacggatac
    57421 cgactgtgta gtcgtaagta cgtccgtcac ccataacacc gacagagcgg atccctggaa
    57481 gaacagtgaa atattgccag atatcacggt caagtccagc agctgcgatt tcttcacgca
    57541 agatagcatc agattcgcgt acgatttcta gcttgtcttc agtgatttcg ccaagaacac
    57601 gaataccaag accaggacca gggaatggct gacgccaaac gattgaatca ggcatgccta
    57661 actgagtccc taattcacgg acttcgtctt tgaataatgt gtttaatggt tcgatcaatt
    57721 caaattgcat atcttctggc agtccaccta cattatggtg agatttgatc gtctgtgctg
    57781 tttctgtacc agattcgata acgtcagtat acaacgttcc ttgtgctagg aaagagacgc
    57841 cttcttcacc agcaagtttt gttgcttcgt catcaaaaac atatacgaat tcattcccaa
    57901 tgattttacg tttttgttct gggtcagata cacctttcaa cttgtctaag aagcgatctc
    57961 ttgcattgac tttgatgatg ttcaagccga attttccgcc tagactttcc attacttgtt
    58021 ccgcttcgcc tttgcgtagc agaccgtggt caacaaagat agatgtcaat tggtcaccga
    58081 tcgctttttg taaaagaacc ccaacgacac tagaatcaac gccacctgaa agaccaagca
    58141 agactttttt gtcaccaact tgttcacgga ttttttctac ttgcatatcg ataaagttat
    58201 ccattgtcca gttaccttca cagtgacaaa catcaaaggc aaagtggcgc agcaattcga
    58261 ttccgtattc ggaatgacgt acttctgcat ggaattggat accataaaaa ttacgtgttg
    58321 tgtcttggat agaagcaatc ggacaatctt tgcttgttcc gactgtttca aagccttcag
    58381 gaactttagt taccaagtca ccatggctca tccatactgt ttgttgtttt ggtgtttctt
    58441 taaacaagac agcttgatcg cttgttactt ctaacaaggc tttcccatat tcgcggtttt
    58501 tagcaggctc tacggaaccg ccaagtttgt acgtgatcaa ttgcatacca tagcaaatcc
    58561 ctaatacagg aatacctaaa ttgaagatct caggatcgat cccaaatgca ttctcatcat
    58621 atacactgtt tggtccgcca gaaagaatga ttccctttgg attcatcgct tttacttctt
    58681 ctgcagtaat gcggtggctc aataattcgg aaaagactcc aagatcacga atacgtcttg
    58741 tgatcaattg gttatactga ctaccgtagt ctaatacgat aatcttttca acgttcgtca
    58801 tatcggcaac gtttgtcaaa tttattaccc ctatcccttt aaattttatc tcaaaatagt
    58861 caaactattt taaaatgcta atattttcgc atgaaaatcg aatcgatgat atgattttca
    58921 gttttatgga gaattatatc ggctcttcct cgtgtaggca agatatattc ctgtaaattt
    58981 ttcaaattca catttttcca tacatctttt gccattttaa aggcttcttc acgatctccg
    59041 atagcaaaac gataataata attctctgga ttttggaaag ccgtatccag taacgcacca
    59101 aaacgatcca aataccattt ttcgatcagc acgggatcgg catcgacata gacagaaaaa
    59161 tcaaaaaagt cgctgacgta gatttgctga ttcgcaggta attgaagcgt attgatcccc
    59221 tcaacgatca agatatcagg ctgctggatc aattcgtact tgtctggaat gatatcatac
    59281 acatcatgtg agtaaacagg tacttttatc tcttcctgac cagattttac acggttcaag
    59341 aaatcgatca gcatctccat atcataactt tcaggaaatc ctttacggtc catgattcca
    59401 cgctctttta atatacgatt tggataaaga aatccgtcag tcgtgatcag ctgaacgttt
    59461 cttcgtttga aggtacgaga caaaatcgtc tgcagcagtc tggctgttgt actttttcca
    59521 acggctacac ttccggcgat cccgataata aaaggcggta cttctacgta tttatgaaga
    59581 aataaacctt tactcaagaa caaagattca aattctttca tataaagata aatcagatga
    59641 gcaagaggta catagatatc tcgaacatcc tgcatggaaa tgcggtcatt caaacttttg
    59701 atattatcta gttcatcttg tgtcaaaggt gcttgcccat tacgataaaa ttctcgccat
    59761 tcttctcttg ccacacggta gtagttcatt ggatcattca tattagcctc ctgcgttctc
    59821 ccatcaatgg aactatttta acacaaaata aacgcaaacc ccaccactta agagagattg
    59881 ccgatctttt tgtataatct ttataataga aagaaacgga gtcttattct tgacttgcgc
    59941 acggatacat aaaaggatag actgttgtca tgaaagaaat gagaaggatg gaagacatga
    60001 caaatcatta ctattctgaa cgcccagata cggcgcacga ttttgaacaa tgggcttttg
    60061 agttaaaagg cagaaccttt caatttgtaa cagattctgg tgtattttca cgtgaaacag
    60121 tggattatgg ttcacgtgtc ctgattgatg ctttcgattg ggaagagtta cctgatgaag
    60181 gaaagatctt agatgtggga tgcgggtatg gaccgattgg gttagctttg gcatttgcga
    60241 cacagcggtt tgttgaaatg gtcgacatta atgaacgagc ggtaagtcta gcgcaaggaa
    60301 acgcaaagcg taaccaaatc gaacatgttg atatccatca atcgaatatc tatgaagcag
    60361 ttcatgaaga aacctatgca gctatcgtaa gcaatccgcc gatccgtgct ggaaaaaaag
    60421 ttgtacatga aattttgaca ggcgcatatc ctcggttgaa gaagggcggt acactgacaa
    60481 ttgtgatcca gaagaaacaa ggagcgccga gtgcgcaaaa gaaaatggaa gaaacatttg
    60541 gtaatgcaga aatcgtcaca aaagataaag gatattatat catcaaaagt gtgaaagaat
    60601 aactagctga aaaatagtgg agcgacgaaa gagtggaact gggcgtgcat gtacgggtac
    60661 gtatcagttc tttttttgtt gagaagtttt taaaaacaaa gaactatttt ttcttcaaaa
    60721 agaaatagta ggaacagagt cgttgttttt tacgataaaa taaataagat acagaacttg
    60781 tatagaaggc tgccaagtcg gtagataaag gaggttttta tcaaaaaaca tactttcctt
    60841 ttttctctat tcttttcttg ggggttttgg tacactgata gggaatttag atagaaggga
    60901 gccaatagga tgaagctgac catcagagat atcgcagaaa tggcaggcgt atcagtaaca
    60961 actgtctcac agattttgaa taacaaagga agcagattta gtgataagac aagaaaaaaa
    61021 gtgttgtcga tcgtgaatga acatcattat aagcccgatt atttcgcttc aaatgtgatc
    61081 aatcgacatt caaagaccat cggaatgatc gtccctgatg tcactgattt cttcttctcc
    61141 aaactgatcg aaggtgtaga gagctatttg aatcctttgg gctatgtgat catgttatgc
    61201 aattctcgtc atagccaaga aaatgagatc aagtatttac aagagctttc ccaccgctca
    61261 gtggacggaa tcttgctggc cacaccaaat attttacctg agaaatatgc attagacagc
    61321 ggtttttatc aaaaaatgcc aatcatttta atcgatcgcg gattgaatcg tcgggataac
    61381 ggacggctta tcgtaaagga atatgagggc gcctatcaag ctgtttcgct gtttattgaa
    61441 aatggccata cgaagatcgg catgctgaag gaaaccactg gatactatca attagaagaa
    61501 cgtttcaacg gatatcgtca tgcgctgaaa gatcatggcc tgccttttaa tgggaaattt
    61561 gttgaacatg gagagttgac tgtccaaggt ggatatactg catcaaaaaa attactcaaa
    61621 cataaagata tcacggctat tttttgcggg aatgatgcca tggcgatcgg atgctatcag
    61681 gcgatcgatg aattgggcaa aaaaatccca gaagatatct cagtcatagg attcgatgga
    61741 ttaaagctgt cagaatacat gattccgcaa ttgacgacag tgcagcagcc aagttttgat
    61801 attggatttt atgctgcacg tttcctgatc gatacgatcg aatttcctca aagaaaagtt
    61861 ccgaacaaag tgttcgaaac aaaattaatt attcgtgaga gcgtaaaagt attgacaaag
    61921 ggctaactcg gcggtatatt gcttatgtaa gcatttacaa aggctagtta gtgctttttt
    61981 tatttttagt aaaccagttt actaaagtgg tttacctttc ctaaaaataa tgtataatac
    62041 cgaatgaaga caaggaggat caggcaatgc gaatggtgga tctgattgaa aaaaagaggg
    62101 atggaaacga gctgtcgaaa gaggaaatcg agtacatcgt cacgaactat acgaatggaa
    62161 agattccaga ttatcaagtc agtgcattat tgatggcaat tttttatcaa gacatgacaa
    62221 atgaagaaat cacgaactta acattggcga ttgctaattc tggtgatgtc atcgatttga
    62281 gttctcttga aggaataaag gtagataagc attcgacagg tggcgttggt gacacgacca
    62341 cattgatttt agccccccta gtagctagtg tcggagtgac agtggctaaa atgtctggac
    62401 gcggtctagg ttacacaggt ggtacactag acaagctaga agcaattccc ggatttcaga
    62461 tcgagctttc ggatgaagaa tttgtacgca ttgttaatga aagtaaagta gcggtaattg
    62521 gtcaatcagg aaacttggca ccggcggaca aaaaattgta tgccttgcgt gacgtcacag
    62581 cgaccgttga ttctcttccg ctgattgcca gttcgattat gagtaaaaaa atcgcggcag
    62641 gagcagatgc aatcgttttg gatgtgacca ctggagacgg tgctttcatg aagaacatcg
    62701 aagatgcaag acgtctggca aagaccatga cgagcattgg gaaactggct aaccgagaaa
    62761 cagtggcggt tatctcagat atgtcagaac ctcttggcga agctatcgga aatagtctag
    62821 aagttgtcga ggcaatcgaa acattacaag gaaatggtcc agaagatcta gtagaaatgt
    62881 gctacgcctt aggaagccaa atggttgttc ttgctggcaa agctaagaca accgatgaag
    62941 caagaacgtt gcttcaagaa gctctggaat caggtaaagc gttagcaaaa ttcaaagaaa
    63001 tgatccaaaa tcaaggggga gacccagcga tcgtggaaca tccagaacga attttgactg
    63061 cacgctacac aatggagctt cctgctaaac aaagcggagt tgtgtcaaaa atcgtggcaa
    63121 atgaattagg aattgctgca atgatgctag gtgctgggcg taaaaccaaa gaagaagata
    63181 ttgatcacgc tgttggattg aaactgcata aaaaaattgg tgacactgtg acaaaaggtg
    63241 agtcactatt gacgatctat agtaacgacg aagaaatcac ttctgtcatt gaattattat
    63301 ataaaaatat tgaaattggt gaatcggcaa tgaagccaac gttgattcat gacatcatca
    63361 cagaataaag gaaaaaagcg gactttaccg ttttaaagaa aaggggaaaa gaaatggaac
    63421 taaaccgaat gatcgaccat actattttga aagcagacgc atctaaagaa gctgtgatgc
    63481 aaattatcga agaagcaaaa aaataccatt tttattctgt ctgcatcaat ccagcatggg
    63541 ttgcgctagc gaaagaacaa ttacaaggtg agccagtagc cgtatgtaca gtaatcgggt
    63601 ttcctctagg agcaaacaca cccgagacaa aagcatttga aacaacagat gccatcaata
    63661 acggtgcaga tgaagtcgat atggtcatca atatcggtgc tttgaaatca aaggatgatc
    63721 aacaagtcca aaaagatatc gaagcagttg ttgaagcagc aaaagatcgt gcgcttgtca
    63781 aagttattat tgaaacatcg ttattagata gagaagaaat catccgagct tgcgaaatag
    63841 caaaagctgc aggcgctgat tttgtcaaaa catcaactgg tttctcaaca ggcggagcaa
    63901 aggtagagga tgtccgtttg atgcgtgaaa ctgtaggacc agaaatgggt gtcaaagctt
    63961 ccggcggtat ccataacgaa gaagaagcaa tggcaatgat cgaagctggt gctacaagaa
    64021 tcggaacaag cgcaggagta gcaatcgtat ctggttcaac tggtgaaggc tattaatttt
    64081 ttcaaaggag aagctcatgg cagaactcaa acaagaatgg atcaacacag ctattgaagc
    64141 gttagataaa gcctatgttc cttattccca ttttccggta ggcgcttgtc tcgtaacgga
    64201 atcaggcaag atttatcaag gcatcaacat tgagaatgca tcatttggat taacgaattg
    64261 tgccgagcgc acagcttttt tcaaagcagt atctgaagga gaaaaaacat ttacgcatct
    64321 agtcgtagcg gggcacaccc ccgatcctat ctctccttgt ggtgcatgtc gacaagtaat
    64381 ggcagaattc tgttcccctg atatgccggt tacgctagta ggagacaatg gtgtgacgaa
    64441 ggcaacgacc gttcgtgcac tgctgcctta tgcatttact gaaaaagatc tataactcat
    64501 gttcattcag tcagctgact gttgaaaaat aaaacaatta ttttaggagg ctttacagaa
    64561 atgaaaaaag caaaattatt tggtttaggt gctgtcgcac tagcagcagg gttattttta
    64621 ggtgcatgcg gcaacaacgg ctctactgat tcatccggtg gcaaaagctc atcagacaca
    64681 acaactgcag cattgatcac agacacaggt ggtgtagacg accgttcatt caaccagtca
    64741 gcttgggaag gactagaaaa atgggggaaa gatcaaggac tttcacgagg aaatgatggc
    64801 ttccaatatt tccaatcttc aaatgaatca gattacatcc caaatattga ccaagcattg
    64861 aatgctggat tcaaaacgat ttttggtatt ggttataaac taaaaccagc gatccaagaa
    64921 caagcaacaa acaatacagg tacgaacttt gttattatcg atgatgtcat cgatggatta
    64981 gataacgttg tatctgcaac tttcaaagac aacgaagctt cttatcttgc aggtgttgca
    65041 gcagcttata cgactgaaac aaacgtagtc ggctttatcg gcggtgtaaa aggtgaagta
    65101 atcgatcgtt ttgatgctgg attcaaagcc ggtgttgatg caggtgcgaa agaattagga
    65161 aaagaaatca aagtattgaa tcaatatgct ggtgacttct ctgctccaga taaaggacgt
    65221 tcaattgctc aaggtatgta tgcacaaaac gcagatatca tcttccatgc ttcaggcggt
    65281 acaggtaacg gtgtattcca agaagcaaaa tcattgaacg aatcaggcga caaaaaagtt
    65341 tgggttatcg gtgttgaccg cgaccaatca gacgaaggcg aatacacatt aaacggcgaa
    65401 aagaaaaact tcacattgac atctacactg aaagcagttg gaacagtagt agaagatttg
    65461 gcacaaaaat cagcggacgg taaattccct ggcggcgaac acactgttta tggattgaaa
    65521 gaagacggtg ttggtctaac agaaggacaa ctttctgacg aagcgaaaaa agcagttgat
    65581 gaagcaaaag aaaaaatcat ttcaggtgac gtaaaagttc cagaaactcc tgaagaaaac
    65641 taaaaccatt tctatagcct tgttagacac atgtttgaca aggctatggt ttgattagaa
    65701 caagaattgt tcatttatcc aagctgcctt gtgacagttt ggataaggga acaactccct
    65761 gaagtaatgt ttgtttcaaa agaagaacgc tcactaagcg tgaatcttag tcaatcgttg
    65821 ccctagatag aaatcgttag gatgtgaaaa aaaggtggtt caagaaaata ttgtcataga
    65881 aatgcagaat attaccaaag aatttggaac attcaaggca aatgacaaca tcaatttaca
    65941 agtaaaggca ggagaaattc atgcgttgct tggagaaaac ggtgctggca aatctacatt
    66001 gatgaacgtg ctttccggat tattagagcc gacatcaggg aaaattttga tgcgtgggaa
    66061 agaagtaaag atcacaagtc cgaccaaagc caaccaatta gggattggga tggtccatca
    66121 gcactttatg cttgttgatg cctttactgt aacagaaaac atcgtgttgg gaagcgagcc
    66181 tagtcgcgca gggatgcttg accataaaaa agcacgaaaa gagatccaaa aagtttctga
    66241 acagtatgga ttgtcagtca acccagatgc ttacgttcgt gatatttcag ttggaatgga
    66301 acaacgggta gaaattttaa aaacacttta ccgaggagca gatgtactga tttttgatga
    66361 gccgacagct gtattgaccc ctcaagaaat tgatgaatta atcgtgatca tgaaggaatt
    66421 agtcaaagaa ggcaagtcga tcattttgat tacgcataag ttagatgaaa tcaaagcagt
    66481 agctgaccgc tgtacagtta tccgccgtgg aaaaggaatc ggtacagtca acgttaaaga
    66541 cgtaacctca caacaattag ccgatatgat ggttggaaga acggtttcat tcaaaacgat
    66601 gaaaaaagaa gcgaagcctc aagaagtcgt tttgtctatt gaaaatctag tggtgaaaga
    66661 aaatcgtgga ttagaagccg tgaaaaactt gaacttagag gttcgtgctg gcgaagtact
    66721 tggtatcgct ggaatcgatg gaaacgggca gtcggagttg atccaagctt tgactggttt
    66781 gcgaaaggca gaaagcggac atatcaagct aaaaggggaa gacatcacta ataaaaaacc
    66841 ccgaaaaatc actgaacatg gtgtaggaca cgtgccagaa gaccgtcata aatacgggtt
    66901 agtcctagat atgacattat ctgaaaatat cgcactacaa acctatcatc aaaaacctta
    66961 cagtaaaaac ggcatgctga attattcagt aatgaatgaa catgccagag aattgatcga
    67021 agaatatgat gttcgaacaa cgaatgaact tgttcccgca aaagctttat caggcggaaa
    67081 tcagcaaaaa gcaattatcg ctcgtgaagt cgaccgagat cctgatctgt tgattgttgc
    67141 aaatccaact cgtggactgg atgtaggtgc gatcgaattt attcataaac gtctgatcga
    67201 acaaagggac aaatacaaag cagtgttact gatcagtttc gaattagaag aaattttaaa
    67261 tgtttcggat cgtattgctg ttatccatga aggagaaatt gtcggtatcg ttgatccgaa
    67321 agaaacatct gaaaatgaat taggtctatt gatggcgggc tataccttag aagaagcacg
    67381 aaaagagtta gaaaaggggg ctggcgcaca tgaatgatcg cagcgaaaaa ttccgtaatt
    67441 tattagtgcc tgtactttca gttgttttag gattgatctt aggcgcgata ttgatggctg
    67501 cttttggttt tcagcccatc caaggttatt cttctatgct agatgcagcc cttggttcgc
    67561 aaagagggat aggtgaaacg ttaaggcaag caacgccgtt gatttttaca gcattaggtt
    67621 tttctgtagc taactcagct gggtttttca atattgggct ttctggacaa gcactttgcg
    67681 ggtggatcgt cagtgtctgg gtggcacttg cgtttccaga tctgccaaaa gttgttttgc
    67741 ttccgttatg cgtgatctta ggtgccttag ctggtgcgat ggcagcggct gttccaggtt
    67801 tacttcgagc attttttgga acaagtgaag tgatcgtaac aatcatgatg aactatatct
    67861 tattatacgt aagcacattt gctttacatg aagtgatgcc tgaaagctat cgctcaagtt
    67921 tggactcttc caatatgatc agtcaaaatg cctcactgcg gttaccatgg ttaacacaag
    67981 cttttggcgg ctctcgcgta aactcaggat tatttttagc aatcatcgcg cttattttcg
    68041 tttggctgct gatgaagaaa acgactttag gatttgaaat ccgttctgtt ggattgaatc
    68101 cttttgcttc tgagtatgca ggaatgagta gtaaacgtac gatcgttttg tcgatggtca
    68161 tttctggcgc tttggcaggg cttggcggtg tggttgaagg attaggaacg tatcaaaact
    68221 tctttgttca aacgacttcg ctatctattg gatttgacgg aatggctgtt tccttgcttg
    68281 gttctggatc agcaatcggt attcttttat cagcgatctt gttcagtatt ttgaagatcg
    68341 gtggacttgg catgcagaca ggagcaggtg ttccgtttga gatcgtcaat gtatcgattg
    68401 ctttgattat cttctttgtc gggatcaact tcctgattcg tttcgtcatg gctaaagtct
    68461 tccaagggaa aaaacaagaa gagatcgttg cgacaataga atcgaaacca acgaatcaaa
    68521 accatgaagg gggcgaacta taatgtcgac tatcgaatta attgccttga tccttacttc
    68581 tacactggtt tattcaacac cgctaattct aacgtcacta ggcggaactt tttctgaacg
    68641 aagcgggatc gtaaacgtag ggctagaggg aatcatggtc atgggtgctt ttagttccat
    68701 cgttttcaac ttgacgatga gtccatcact tggttctatg acaccatgga tcgctatttt
    68761 agtgggtggc gtcgtaggta tcctattttc tctgattcac gcagtagcaa cagtcagttt
    68821 gcgtgctgac catattatca gcgggacagt aattaatctg atggcacctg ctttaggtgt
    68881 tttcttgatc aaagcatggt atggtaaagg tcaaactgat aacatcacgc agaatctggg
    68941 gtatttttct ttcccaggat tagcagatat tccggtcatt ggaccaattt tctttaaaaa
    69001 tacattctta cctgcttatt gtgctatttt gattgctgtc ctagcttggg tgatcatctt
    69061 caagacgaaa ttcggcttgc gcctccgttc agttggtgaa aatcctcaag ctgccgacac
    69121 attaggtatc aatgtatatg ctatgcgtta ttcaggcgta ctgatttctg gcttgttagg
    69181 cggtatgggc ggtgctgttt ttgctcagtc gatttccggt aacttttcag ctggtacgat
    69241 cgttggacaa gggttcatct ccatggctgc tatgatcttt ggtaagtgga atcctttagg
    69301 ggcaatgggt gcctcattgt tctttggttt tgctcaaagc ttgagtatca ttggcgcaca
    69361 attaccagtt atttcttcga ttccgccagt attgctgcaa attgctccat atttgctgac
    69421 aatcattgtg ctggttgttt tcttagggaa agcttctggt ccaaaagcaa acgggaagaa
    69481 ctatatcaaa tcaaaataat cttttagcga ataaaaaggg tgggttacgg gaagtgtttt
    69541 tcgtctcgcc ctttttgttt taaaggcaat aaaaataaaa agaaagaagg aataatcatg
    69601 tttaaacgcg tacatctgat cgtcatggat tcagtaggaa ttggagaagc accagatgcc
    69661 gataagttcg gtgatgttgg ttctgataca ttaggacaca ttgcgaaaga agcaggattg
    69721 aacgttccac atttagagca gcttggttta ggaacgatcc gtcctcttga aggtgtggaa
    69781 tcagtgaaag atcatcaagg ctatgcgacg aaattagaag aagtttctgt agggaaagat
    69841 acgatgacag gccactggga aatcatggga ttgaatatca aaactccatt tcgtgtgttt
    69901 cctaatggat tccctgatga tctgatcaaa caaatcgaag aattttctgg ccgtaaagtc
    69961 gtatgtaaca aaccttatag cggaacagct gttattgacg attacggtga acaccaaatg
    70021 aaaacaggcg atttaattgt atatacttct gccgatcctg tccttcagat cgcggcacat
    70081 gaagaaatca ttcctttaga agaattatat cggatttgcc aattcgttcg tgatataaca
    70141 aaagatgatc cgtatatgat tggccgaatc attgcacgtc cgtacgtggg tgaaccagga
    70201 gacttcacac gaacaagcaa tcgccatgat tatgcgttga atccattcgg acacacagtc
    70261 cttgattctt tgaaagaagc aggaaaggac gtgattgctg ttggaaagat caacgatatt
    70321 ttcaacggac aaggaatcac tgaatctgtc cgcacgaaaa gcaatatgga tggcgttgac
    70381 cagctgctga aagttatgaa aaacgatttt tcaggaatca gctttaccaa tttagtagat
    70441 tttgatgcat tatacggtca tcgtcgggat gtagtcggct atgcgcatgc gattgaagaa
    70501 tttgacttac gaattccaga attgcttgaa gcgatggaag aagacgactt gctaatgatt
    70561 acagccgatc acggaaacga tccgacgttt actggtaccg atcatacgcg agaatatgta
    70621 ccgttattgg tttacagtaa aaaaatgaaa gaacaagggg cattgcctca aggatattat
    70681 tcagatattt cagcaacgat tgctgagaac tttagtgttt cttcgactga aaatggcgaa
    70741 agcttcttga aattattaaa ataatctttt taaataggag aaagcaaatg accaagttaa
    70801 gcgagatgtt acaagaaacg acccagttta tccttgataa aggagtaaaa gaaattgatt
    70861 ttggtttgat tctaggttca ggattaggtg aattagcaga tgaaatcgaa gatgctgtaa
    70921 tgatttctta tgatgagatc ccgttctttc ctgtttcgac agtagttggg catgcaggaa
    70981 agctagttta tgggtctctg gcaggcaaga aagtgttagc catgcaaggg agattccact
    71041 actatgaagg tcattccatg caaacagtga cctatccagt acgtgtgatg gccggactag
    71101 gggcccattc agtcattgtg actaatgcat gtggtggtgt caacgaatca tttgtaccag
    71161 gagatttgat gctgattacc gatcatatca attttactgg tgaaaatcct ttgatcggtc
    71221 cgaatgaaga tgcaatgggc cctagatttc cagatatgag tcaagcttat acgcctgact
    71281 atcaagcaac agcaaaagca gcagcagaaa aactaggttt ggatcttaaa gaaggcgtat
    71341 atatgggcta ttctggacca acttatgaaa cgcctgcgga gatccgaatg tctcggacaa
    71401 taggagccga tgcagtaggg atgtcgactg ttccagaagt catcgtagca gctcacagcg
    71461 gattaaaagt gttaggaatc tcttgtatta ccaacttagc agcaggtatg caagcgaatc
    71521 tgagccatga agaagttgta gaaacaactc agagagtcaa acaatctttt aaagcattgg
    71581 ttaaagaaac attgacatta ttgtaatagg aggaacaata aaatgagtgt gcatattgaa
    71641 gcgaaagaag gcgagatcgc cgataagatt ttacttccgg gagatccttt gcgagctaaa
    71701 tatattgcgg agactttttt ggaagatcca gtttgttaca atcaggtacg cggtatgtta
    71761 ggctttaccg gcaaatataa aggagaacgt atttctgttc aaggaacagg aatgggaatg
    71821 ccatcagcca ccatctatgc ccatgaattg atccagtcgt atggtgtaaa gaaattgatt
    71881 cgagtaggta catgcggtgc attgtcaaaa gacgtccatg ttcgtgattt agtactagca
    71941 caaggtgcag cgaccagttc ttcgatgatc gaaaaaaatt tccaagcctt tcattttcct
    72001 ccaatcagtg atttcaatct attactgaaa gcatatgaga tagctaaaga aaagggctat
    72061 acggttcatg taggaaatgt tctttcggaa gattctttct acaaagatga tttgacagag
    72121 acgttccaat tagctgaact tggcgtttta ggagtggaaa tggaagcagc ggctctttat
    72181 tacttaggcg cgaaatacca tgtgcagaca ttaagtttga tgaccgttag cgaccatttg
    72241 atcaccggtg aagaaacaac agctgcagaa cgtcaatcta cgttcaatga aatgatcgaa
    72301 gtaggattgg aaacagcgat agcagaataa gaaggaaatg aaaaagctgc cctgcattaa
    72361 gtaataagaa catccaagca aaaatagctc ctcatgtttt tgacttggct ggacttatta
    72421 ttgcaaatgt aagcttttga acaccgttta ccaagaggtt gtgaatctgc cgtttaactc
    72481 tgagtcacaa ggaacaattt caaaaaacag cttttcatgt ttgatgaata ttgtgacttg
    72541 tgaccgagaa gttggcagga gaaaaccgtt tatacgaaaa aagggactgt gacaaatcgt
    72601 gtcacagtcc cttttttata gtgtttttta taggtagtat tttttagcaa ctgttaagtc
    72661 atcatttaat tcataaacaa gtggttgacc tgttggaatt tcaagatcca tgatgtcttc
    72721 gtcagagata ccttcgatat gtttagctag ggcgcgtaat gagttaccat gtgcagctac
    72781 taaaacagtt ttgttgtcta gtaatgctgg agcaatttca tcttgccaga atggcaaagc
    72841 gcgttctaat gtcactttca agttttctcc accaggaata tcgcgtttgt ctaacattgc
    72901 gtaacgacgg tcatttgctg cagaaccttc gtcagtttct tccattaatg gaggaagagt
    72961 atcgtaagaa cgacgccaga tgtgcacttg ttcgtcgccg tatttttcag ctgtttcttt
    73021 tttgttcaaa ccttgtaatt taccatagtg acgttcgttt aagcgccatg atttgatttg
    73081 tggtacccaa agttgatctg aatattctaa gatcaagtta catgttttga ttgcacgagt
    73141 taaaacagaa gtgtaagcaa catcaaattc gattccagct tctttgattt tgcgtccgcc
    73201 ttcttttgct tcttcgattc cttctggtgc tagatttaca tcagcccaac cagtaaattg
    73261 gttcaatgca ttccattcac taagaccgtg acgagaaaaa actaattttg gcatgtttag
    73321 ctctcctttt aagataggtt tatatttctg aaattttcag ttctgtttta ttgtacaatt
    73381 ttttggaaga gatttccatc gaaaaattag ataagattct atgagaaaac aagtagagaa
    73441 tataaaaaaa cgaacagtgc ccacgcaact gttcgttttt aggtattaga tgcataattg
    73501 ctcgatttct ttttcaggta aattgatata tttataacat gttccaactg aaacaccgca
    73561 ttttgaagaa ataaattgga tcgtttcttt tttttcataa tagagacgtc ggattttttt
    73621 gatcgttttt gcatcgattt ttggtcttcc gccgattttt ccttttttac gagcttcatc
    73681 taatccaact aatgtacgtt ctttgatcaa tgcgcactcc atgtttgcta ggttttccat
    73741 taattggaaa tagatttttc ccatttcgcg cgtatcgatt ccttcatcaa gactaatcaa
    73801 gtgcagcccg cgatctttga ataattgcgt gagttctgtt aattgccgcg tagatttgcc
    73861 taatcgatga agttggcaaa tgactagtgc atcgccttgt tgcatgtcag cgatcactga
    73921 ctccaaatga acagcagtag aatcattttg ttccacttca tatgtctcat ggaaaatttc
    73981 ttgacaacca aagtcagata attgatcaac ctgagttgtt aaatcaacgt catttatggt
    74041 tgtgcgtgca taaccaataa ttttcatggt gattcctttc tagcagtgat tttctaactg
    74101 gatataacag taaaaatgta gcataaagta cgtcaaaaag atagtttttt cgcaaatttt
    74161 ccgctgtctt tttttattgg atgatcaagc agtttttctt tatttacgac ggattgcgtc
    74221 aagaatctca acgccttttt ctgagccgac aactacttta gaaaccatgt ttaggaaaag
    74281 cccatgttct actaccccaa caagttcatc taaataggta gctaagcttt ctggctgttc
    74341 gatgacttct agatgcagat caatgatgta atgaccacca tctgtggtta agacttctcc
    74401 gttttcgtct gtacgcaaga cgggttggaa tcttttttct tcaaaaatat gaagtagctg
    74461 ttgggagcca taagggatca cttcaactgg gagtgggaac ttcccaagtt tatcgactaa
    74521 tttagaagaa tcaacgatcc aaatcgtttc ttttgagtac gtagcgacta ttttctcgaa
    74581 aagcaaagca gcgccgccgc ctttgatccc ttgaaaatca gcactgattt catcagcacc
    74641 gtctattgtc aaatcgacta cggggacttc atcaatactc tttaacggta ttcctaattt
    74701 ttccgcttgt tcttttgtcg catttgaagt agtaactcct gtgatacgta aaccttcttc
    74761 acgcatacgg cgaccaatct cttctaccat ataataggcg gttgaaccgg tcccgagacc
    74821 tacgatcatc ccgtccttta cgaatttcgc ggcttcaatg ccagctaatt gttttaaatt
    74881 catctttgcg tccacctttt tttagtttga gcatcgtgct ttcctcacta ttttagcgtg
    74941 atttacggta aaaagatacc attctttttt attccaataa agctttttca aaaaaaattg
    75001 catctcttgt tgacatgttt tttcattcgt gatattctaa caaaggtgct ttatctacag
    75061 gtttctgtga agaaacgtgc tgactgttta tcaaagcata tttgataagg atgcagacat
    75121 tgcatttatt ttttatcaca aaaaaagaac cacctggatg tgtggaacta gacgcaaatc
    75181 gtgggaagga ggaaacaagg aatgcctaca attaaccaat tagtacgtaa acctcgtaaa
    75241 tcaaaggtgg aaaaatctaa ttcacctgct ttgaacaaag gatataacag ctttaagaaa
    75301 actcaaacta acgtaaactc acctcaaaaa cgtggggtag caactcgtgt gggtacaatg
    75361 acacctaaaa aaccgaactc agctttacgt aaatatgcac gtgttcgttt gtcaaactta
    75421 attgaagtta ctgcttatat cccagggatt ggtcataact tacaagaaca cagtgttgta
    75481 ttattacgcg gtggtcgtgt aaaagactta ccaggggtac gttaccatat cgttcgcggt
    75541 gctttagata ctgctggtgt taacgaccgt aaacaaagcc gttctaaata cggaactaaa
    75601 aaacctaaag cttaatttta attattaaac aaatgaaact tgcttctact atatagaagt
    75661 aattactatg aacaatattt cggaaggagg agttacggat gccacgtaaa ggtcctgttg
    75721 caaaacgtga tgttttacca gatcctattt ataactcaaa attagtaact cgcttgatca
    75781 accgtgtaat ggttgacgga aaacgcggga ttgcagctaa cattatctat aatgcctttg
    75841 acttgatcaa agaatctaca ggtaacgatc cattagaagt gtttgaacaa gcaatgaaaa
    75901 acgttcaacc tgttcttgaa gttaaagcac gtcgtgttgg gggttcaaac taccaagtac
    75961 cagttgaagt tcgccctgaa cgccgcgtta ctctaggtct tcgttgggta gtaaactacg
    76021 ctcgcttgcg cggtgaacac acaatggaag aacgcttagc aaaagaaatc atggatgctg
    76081 caaacaacac aggtgcttct gttaaaaaac gtgaagacac tcataaaatg gctgatgcca
    76141 accgtgcgtt tgctcactat cgctggtaag attctctctg tttggtcggc ttttataagt
    76201 cgacctcaga tagtgtcctt atttttagca actagatagt aaagagagga gaaacaagga
    76261 gaatgaccag agaattttct ttacaaaaca ctcgtaatat cggtatcatg gcccacatcg
    76321 atgctggtaa aacgactgct actgaacgta tcttgtacta tactggtaaa atccataaaa
    76381 ttggtgaaac tcatgaagga gcttcacaaa tggactggat ggaacaagaa caagaacgtg
    76441 gtattacgat cacttctgct gctactacag cacaatggaa gggtcaccga atcaacatca
    76501 tcgacacacc aggacacgta gacttcacag ttgaagttga acgttcattg cgtgtacttg
    76561 atggtgctgt aactgttctt gatgcacaat caggtgttga acctcaaact gaaacagttt
    76621 ggcgtcaagc aacaacttat ggtgtacctc gtatcgtatt tgcaaacaaa atggacaaga
    76681 tcggtgctga cttcttatat tcagtatcaa ctttacatga ccgtttgcaa gcaaacgctc
    76741 acccaatcca attaccaatt ggtgcggaag acgacttcac aggaattatc gaccttgtaa
    76801 caatgaaggc tgaaatgtat acaaacgatc ttggaacaga gatcgaagaa acagaaattc
    76861 ctgaagaata ccgcgaatta gctgaagaat ggcgcgaaaa attggttgaa gctgtagctg
    76921 aaactgatga agaacttact ttgaaatact tagaaggtga agaaatcact gaagctgagt
    76981 taaaagaagg tatccgccgc gcaacagtta acgtagaatt ctacccagta ctatgtggtt
    77041 cagcatttaa gaacaaaggg gttcaattac tattggacgc tgttcttgat tacttgccat
    77101 caccgttaga tatcccagct atcaaaggga ttgaccctaa aactgatgaa gaagtagaac
    77161 gtcctgcaga cgacagcgct cctttctcag ctttagcatt taaagttatg actgacccat
    77221 tcgtaggtcg tttaactttc ttccgtgtgt actctggtgt tttacaatca ggttcatacg
    77281 tacaaaacgc aacaaaaggc aaacgtgaac gtgttggtcg tatcctacag atgcatgcca
    77341 actctcgttc agaaatctct gaagtttacg ctggagatat cgctgctgct gttggtttga
    77401 aagacacaac tactggggac acactatgtg atgaaaagag tctagttatt cttgaatcca
    77461 tggaattccc agaaccagtt atccaagtcg ctattgaacc taaatcaaaa gctgaccaag
    77521 ataaaatggg tgtggcttta caaaaactat ctgaagaaga tcctactttc cgtgctgaaa
    77581 caaacgtgga aacaggcgaa acaatcatcg ctggtatggg tgaacttcac ttagatatca
    77641 tcgttgaccg tatgcgtcgt gaattcaaag ttgaagctaa cgtaggtgcg cctcaagtat
    77701 cttaccgtga aactttccgt gctggcactc aagccgaagg taagtttgta cgtcagtctg
    77761 gtggtaaagg tcaatacggt cacgtatgga ttgaatttac accaaatgaa gaaggtgctg
    77821 gtttcgaatt tgaaaatgcg atcgtcggtg gggttgttcc tcgtgaatac attccagctg
    77881 ttgaaactgg tttgaaagat gctatggaaa atggtgtctt agctggctat ccattagtag
    77941 atatcaaagc taaactttac gatggttcat accatgatgt cgattcaaat gaaactgcct
    78001 tccgtgttgc tgcttctatg gcattacgtg cagcagctaa gaaagctaat ccagtaatcc
    78061 ttgaaccaat catggctgta gaagttgtta tccctgaaga ttatttaggt gatgttatgg
    78121 gtcacgtaac tgctcgtcgt ggacgtgttg aaggtatgga agctcgcgct ggcggccaac
    78181 aagttgttcg tgcgatggtt ccacttgctg aaatgtttgg ttatgctaca actcttcgtt
    78241 ctgctactca aggtcgtggt acatttacaa tgacatttga ccactacgaa gatgtaccaa
    78301 aatcagtaca agaagaaatc attaagaaaa acggcggaaa agctgaataa tttcttgaaa
    78361 ccggatagtc ctgcaaagag attatccaaa gagactatat ttttaatata gtttcgtgta
    78421 aaataattat cgatgatatg ggcatgtggt gtaccttgtg tacatcatat acctatcaga
    78481 caaataaaaa atatattgta tttttaggag gacattttaa aatggcaaaa gaaaaatttg
    78541 accgttctaa accacacgtt aacattggta ctatcggaca cgttgaccat ggtaaaacta
    78601 cattaacagc tgcaatcaca actgtactat ctaagaaaaa cggcggccaa gctatggctt
    78661 acgatcaaat cgatggtgct ccagaagaac gcgaacgcgg aatcacaatc tcaacagctc
    78721 acgttgagta tgaaacagat acacgccact acgctcacgt tgactgccca ggacacgcgg
    78781 attacgttaa aaacatgatc actggtgctg ctcaaatgga cggagctatc ttggtagttt
    78841 ctgctgctga cggcccaatg cctcaaactc gtgaacacat cctattgtct cgtcaagttg
    78901 gtgttcctta catcgttgta ttcttgaaca aagtagacat ggttgatgac gaagaattac
    78961 tagaattagt tgaaatggaa gttcgtgacc tattaacaga atacgaattc cctggtgacg
    79021 atgttcctgt agttgctgga tcagctttga aagctctaga aggcgacgct tcatacgaag
    79081 aaaaaattct tgaattaatg gctgcagttg acgaatacat cccaactcca gaacgtgaca
    79141 acgacaaacc attcatgatg ccagttgaag acgtgttctc aattactgga cgtggtactg
    79201 ttgctacagg tcgtgttgaa cgtggacaag ttcgcgttgg tgacgaagtt gaagttgttg
    79261 gtattgctga agaaacttca aaaacaacag ttactggtgt tgaaatgttc cgtaaattgt
    79321 tagactacgc tgaagctgga gacaacattg gtgctttact acgtggtgtt gcacgtgaag
    79381 acatccaacg tggacaagtt ttagctaaac caggtacaat cacacctcat acaaaattct
    79441 ctgcagaagt atacgtgttg acaaaagaag aaggtggacg tcatactcca ttcttcacta
    79501 actaccgtcc acaattctac ttccgtacaa ctgacgtaac aggtgttgtt gaattaccag
    79561 aaggaactga aatggttatg cctggcgaca acgtaacaat ggaagttgaa ttaatccacc
    79621 caatcgctat cgaaaacggt actaaattct caatccgtga aggcggacgt acagttggtg
    79681 ccggtgtcgt tacagaaatc aaagcttaat tcacttaagt tttaaagtaa agcaacattt
    79741 attcggacgt aatcgctcgg aacgaaggtc ttaggatctt tgttccgagc ttttttattt
    79801 attgcaggat caggaaaaaa gacaggagta ttataaatag aagaaacacg aaataaaaga
    79861 gtcagtattt tctaaatgaa actttatgaa aacaaaatgt tttttacaag aaaaagcctt
    79921 gctttgtgag tttatatata ttataatgac aaaggtgcgt ttactttagt gaattgcaca
    79981 gacgtaatca gaatgatttc gtcggctaag aaacgagagg ttgcgacacg cccggacgct
    80041 ttgccacgaa cgagcgtgac ggaaattttc gtggagctat gtctactttt caaaataggc
    80101 gaaggaggga acaagatggc aaaacaaaaa attcgtatcc gtttaaaagc gtatgaacac
    80161 cgtattttag atcaatcagc ggataaaatc gtggaaactg caaaaagaac tggagctagc
    80221 gtgtctggtc caattccatt accaactgaa cgcagtcttt acacaatcat ccgtgcgact
    80281 cataaataca aagattcacg cgaacaattc gaaatgcgta cacacaaacg tcttatcgac
    80341 attgtgaacc caacaccaaa aactgttgat gctttgatga agctagactt accatctggt
    80401 gtaaacatcg aaatcaaatt ataaaactaa aacaaaaata atggaggtgt actcatgacc
    80461 aaaggaatct tagggaaaaa agtgggaatg acacaaatct tcactgaatc tggtgaatta
    80521 attccagtaa ctgttgtaga agctactcca aacgtagtac tacaagtgaa aacaatggaa
    80581 acggatggct acgaagctat tcaagttggt taccaagata tgcgtgaagt tttatcaaac
    80641 aaacctgcga aaggtcatgt tgcaaaagca aacacggctc ctaagcgctt cattcgtgaa
    80701 ttcaaaaatg ttgagctagg agaatatgaa gtaggaaaag aaattacagt agatgttttc
    80761 caagcaggag acattattga tgtaacaggt actacgaaag gtaaaggatt ccaaggggtt
    80821 atcaaacgcc acggacaaag ccgcggacca atggctcacg gttctcgtta ccatcgtcgt
    80881 cctgggtcaa tgggtccagt tgcacctaac cgtgtattta aaaacaaacg tcttgctggc
    80941 cgtatgggtg gcaaccgcgt aactatccaa aacttggaag ttgtacgtgt cgatgcagaa
    81001 agaaatgtta tcttgatcaa aggtaatgtt cctggagcta aaaaatcttt aattactatc
    81061 aaatcagctg tgaaagctaa ataattgtag gaagaaagga ggaactaagg aatgccgaat
    81121 gtagcattat tcaaacaaga tggaagccaa aacggtgaaa tcacacttaa cgaagaaatc
    81181 ttcggaattg aacctaatga aagtgttgtt tacgatgcaa tcgtaatgca acgtgcgtca
    81241 ttaagacaag gaacacacgc ggttaaaaac cgtagcgctg ttcgcggcgg cggacgtaaa
    81301 ccatggcgtc aaaaaggaac aggtcgtgca cgtcaaggat ctatccgctc accacaatgg
    81361 cgtggaggtg gcgtagtctt tggaccaaca ccacgttctt acagctacaa acttcctaaa
    81421 aaagttcgtc gtttagcaat gaaatctgta ttgtcagaaa aagttgctga aaacaacttg
    81481 gtagcaatcg aaggcttgaa cttcgacgca ccaaaaacaa aagaattcaa acaagttctt
    81541 gctaacttat ctatcgactc taaagtattg gttgttctag aaaaaggtaa cgactttgct
    81601 gctttatcag cacgtaactt accaaacgtt tctgtagtaa cttctgataa tgtgagtgtg
    81661 ctagacgttg tatcaaatac aaaagtgtta gcaacacaaa ctgctcttac tcaaattgag
    81721 gaggtgcttg cataatgaac ttactagacg taatcaaacg cccagtgatc actgaaaaat
    81781 caatgcttgc catggatgac aagaaataca cttttgaagt ggacactcgc gcaaacaaaa
    81841 ctttagtaaa acaagcggta gaagctgctt ttgacgttaa agtcaaaaac gtgaacatcg
    81901 tgaacgtacg tgcgaaattc aaacgtatgg gcaaatatgc aggatataca aaaaaacgtc
    81961 gcaaagcgat cgttacattg actgaagatt caaaagaaat ccaattattc gaagctgctg
    82021 aataagcact aatagataac tcattaaatt aggagggaaa aacgtggcga ttaaaaagta
    82081 caaacctacc tcaaatggtc gtcgtaacat gacaggttct gattttgctg aaatcacaac
    82141 atcaacacct gaaaaatcat tgttacaacc attgaaaaac catgctggac gtaacaacaa
    82201 cggccgcatc actgtacgtc atcaaggtgg cggacacaaa cgccaatatc gcgtgatcga
    82261 cttcaaacgt aacaaagata acgttgttgc aactgttcaa acgatcgaat atgatccaaa
    82321 ccgttcagct aacatcgcgt tagtacacta tgaagatgga gtgaaagctt acatcttagc
    82381 acctaaagga ctagaagtgg gtatgaaact tgtttcaggt ccagaagcag atatcaaagt
    82441 cggaaatgct cttccattag aaaacattcc agttggtact gttatccaca acattgaaat
    82501 gaaacctggt aaaggtggac aattgatccg ttctgctggt acaagtgctc aagtacttgg
    82561 taaagaaggc aaatacgtat tgatccgctt gaactctggt gaagttcgta tgatcttagc
    82621 tgcatgccgt gctacaatcg gttctgtagg taacgaacaa cacgaattaa tcaacatcgg
    82681 taaagctgga cgctctcgtt ggatgcgtaa acgcccaact gtacgtggta gcgtaatgaa
    82741 ccctaatgat cacccacacg gtggtggtga aggtaaagct cctatcggac gtaaagcacc
    82801 agtttctcct tggggtcaac cagctcttgg ttacaaaact cgtaacaaaa aagctaaatc
    82861 agacaaactt attgttcgtc gtcgcaaaaa taaataatta ctttgaccat gtgtcgcaca
    82921 ttttgagagg aggttcacca tgggtcgtag tttaaagaaa ggaccttttg tcgatgagca
    82981 tttaatgaaa aaagttgaag ctcaagcagg ggttgaaaag aaaaaagtta tcaaaacttg
    83041 gtcacgccgt tcaacagttt tcccaagttt tgttggatat accatcgcag tttatgatgg
    83101 acgtaaacat gtaccagttt acatccaaga agacatggta ggacacaaat taggtgaatt
    83161 tgcacctaca agaacttatc gtggacatgc tgctgacgat aagaaaacga aacgctaatt
    83221 tgaggggagg ataaatccaa atggcagaac aaatcacatc agctaaagca actgcaaaaa
    83281 cagttcgcac ttcacctcga aaagcccgtt tagtaattga ccttatcaga ggtaaaagtg
    83341 tcgcagatgc aatttcaatc ttgaaattca caccaaacaa atctgctgga atcattgaaa
    83401 aagtattgat gtcagcagtt gcgaatgcag aaaataactt tgacttagat gttgaaaact
    83461 tggtagtaag cgaagctttt gttaacgaag gacctacaat gaaacgtttc cgtcctcgtg
    83521 caaaaggatc agcttctcca atcaacaaac gtacaagtca tatcacggta gtcgtatcag
    83581 aaaaataagg agggataatc agtgggtcaa aaagtacatc caattggaat gcgtgtaggc
    83641 atcatccgcg actgggatgc taaatggtat gctgaaaaag agtatgctga gttcttacac
    83701 gaagatttaa gaatccgtaa atttatttca actaaacttg ctgatgctgc tgtatcaaca
    83761 gttgaaatcg aacgcgcaac aggtcgcgta aacatttcaa ttcacacagc taaaccaggt
    83821 atggttattg gtaaaggcgg ttctgaagtc gaaagcctaa gaaaagaatt aaacaaatta
    83881 actggtaaaa gaatccatat caatatcgtg gaaatcaaaa aaccagatct agatgcaaaa
    83941 ttagtaggtg aaggaatcgc acgtcaatta gaaaaccgtg ttgctttccg tcgcgctcaa
    84001 aaacaagcca tccaacgctc aatgcgtgct ggcgctcaag ggatcaaaac tcaagtatct
    84061 ggtcgtctaa acggagcaga tatcgctcgt tcagaaggat actcagaagg aactgttcct
    84121 cttcatactt tacgtgcgga cattgattac gcatgggaag aagcagatac aacatacgga
    84181 aaactaggag ttaaagtgtg gatctatcgt ggagaaattc ttccaactaa aaaaaacact
    84241 gagaaaggag ggaaataatc atgttagtac ctaaacgtgt aaaacaccgt cgtgaattcc
    84301 gcggaaaaat gcgcggggaa gctaaaggcg gaaaagaagt agcattcggt gaatacggtt
    84361 tgcaagctgt tgattcacat tggatcacaa accgccaaat cgaagctgct cgtatcgcaa
    84421 tgactcgtta catgaaacgt ggtgggaaag tatggattaa aattttccct cacaaatctt
    84481 atactgccaa agcaattggg gtacgtatgg gttctggtaa aggggcacct gaaggatggg
    84541 ttgcaccagt aaaacgtggt aaaatcatgt ttgaaatcgc aggcgttcct gaagaagtag
    84601 ctcgtgaagc gttacgtcta gcttctcaca aattaccaat gaaaactaag atcgtaaaac
    84661 gtgaggaaat gggtggtgaa tcgaatgaag gttaaagaaa tcagagaatt aaccactgcc
    84721 gaaatgcttg atcaagaaaa acaattaaaa gaagaattgt ttaatcttag attccaatta
    84781 gcaacaggtc aattagaaaa cactgcacgt attaaagaag tacgtaaatc gattgcacgc
    84841 atcaaaactg tgttgcgtga acaagctaag taattatgga aggaggccat taagcgtatg
    84901 actgaaggaa gaaatcaacg caaagtttat caaggtcgcg tggtttcaga caaaatggat
    84961 aaaacaatta ccgttgctgt cgaaacaaag aaaaaccacc ctatctatgg caaacgcatg
    85021 aactattcta agaaatacaa agtgcatgat gaaaacaaca cagcaaaagt tggcgacatc
    85081 gtgagaatta tggaaactcg tccattatca gctacaaaac gtttccgttt gttggaagta
    85141 gtcgaagaag cagttattat ctaataacac gagattttcc tatatagatt gaatgcaaaa
    85201 tctgaaagga ggatacacaa cgtgatccaa gcagaaagtc gtttaaaagt cgctgataac
    85261 tcaggcgcac gtgaaatttt gacgatcaaa gtccttggtg gatctggtcg taaaactgct
    85321 aacatcggtg atgtgatcgt tgctacggtt aaacaagcaa cgccaggtgg ggttgtcaaa
    85381 aaaggtgacg tcgttaaagc cgttatcgtt cgaacaaaat caggagctcg tcgtacagac
    85441 ggttcatata ttaaatttga tgaaaatgct gcagtgatta ttcgtgatga taaaagccct
    85501 cgtggaacac gtatctttgg gccagttgca cgtgaactac gtgaaaacaa cttcatgaag
    85561 atcgtttcac tagcaccaga agttttataa tcttgagaca cttatcaaag gaggtgcgaa
    85621 acagttatgt ttgttaaaaa aggcgataaa gttaaagtta tcactggaaa agacaaaaac
    85681 aaagaaggcg ttgtactagc agcgttcccg aaaaaagata aagttattgt cgaaggtgta
    85741 aatgtcgtta aaaaacacca aaaaccttct caagctgctc ctcaaggtgg aattgttgag
    85801 atggaagcgc caattcatgt ttctaacgtg atggtggttg actctactgg tgtagctggc
    85861 cgagttggct acaaagaagt agacggcaaa aaagtccgtg tttctaaaaa aaccggtgaa
    85921 gttttagata aataaaagtt taaggaagga gggtcttact gaatgaaccg cctaaaagaa
    85981 aaatatctta aagaagtaac tccatcattg atggaaaaat ttaactatag ctctgttatg
    86041 caaacaccta aagttgaaaa aatcgtcatc aacatgggtg ttggtgatgc ggtatcaaac
    86101 gctaaaaact tagataaagc agttgaagaa ttaactttga tcactggtca aaaaccaatg
    86161 attacaaaag ctaaaaaatc aatcgctgga ttccgtttac gtgaaggaat gccaattggt
    86221 gcaaaagtta cattgcgcgg agaaagaatg tacgaattct tagacaaatt ggtttctgtt
    86281 tcactaccac gtgtacgtga cttccatggt gtaagtaaaa aagcctttga cggtcgtgga
    86341 aactatactt taggtattaa agaacaattg atcttcccag aagtagatta tgatttagta
    86401 gataaagtac gtggtatgga catcgttatt gtaacaacag caaactctga tgaagaatct
    86461 cgtgagttgt tgacacaatt aggcatgcca ttccaaaaat aattaaagga ggcgaactac
    86521 gtggctaaaa aatcaatgat tgctaaaaac aaacgtcctg caaaattttc aacacaagct
    86581 tatactcgtt gcgaacgttg cggacgtcca cattcagttt atcgtaagtt ccatctttgc
    86641 cgtatttgct tccgcgaact tgcctataaa ggtcaaattc ccggcgtgaa gaaagctagc
    86701 tggtaaaaag taaattcgca taagaaggag gtaaaagatc aatggtcatg acagatccaa
    86761 ttgcagattt tctaactcgt atccgtaacg caaacatggt taaacatgag tctttagaag
    86821 tacctgcatc aaaaattaaa cgtgacatcg ctgaaatctt gaaacgtgaa ggtttcgttc
    86881 gtgatgttga atacatcgaa gatgacaaac aaggcgtgat ccgtgttttc ctaaaatttg
    86941 gtaaaaacgg cgaacgtgtt atcacaaact taaaacgtat ctctaaacca ggtttgcgtg
    87001 cttatgtcaa agctgacgaa gtaccaaaag tattgaacgg tttaggtatc gcaatcattt
    87061 cgacttctga aggtgttgtc actgataaag aagctcgtga aaaaaatatc ggcggcgaag
    87121 ttatcgctta cgtatggtaa tcaagtagaa tctacaagga ggtgtcttta agtgagccgt
    87181 atcggaaata aagtcgttgt tatccctgaa ggagtaacag ttactcaaga cggaaacaac
    87241 gttacagtta aaggaccaaa aggtgaattg actcgtactt tttcagcaga tatcaaaatg
    87301 aatatcgaag gaaacgaagt aactttcact cgtccaaacg acagtaaaga aatgaaaaca
    87361 attcatggaa caactcgtgc gaacttcaac aacatggttg taggtgtcag cgaaggtttc
    87421 caaaaagcgt tagaactaat cggggttggg taccgtgcac aattacaagg atcaaaactt
    87481 gtattgaacg ttggttactc acatccagta gaaatcacac caccagctgg agtaactgtt
    87541 gaagtaccag ctaacacaca agtaattgtt aaaggtgcga acaaagaaga agttggcgaa
    87601 ttagctgcaa acattcgtgg aactcgtcct ccagaacctt ataaaggtaa aggtattcgt
    87661 tatgttggcg aatatgtacg ccgtaaagaa ggtaaaactg gtaaataatc gtttagaaaa
    87721 attgcataga agccagcagc aggaaaaagg catttggctg aagtttacct tcaaaaaaat
    87781 acatttttac ttgtgccgca gcttctattt ttcgaaacgt atttactgct tgaaatagta
    87841 gtacaataaa aataaagagg tgacaattgt gattacaaaa ccagataaga acaaaacacg
    87901 tcaaaagaga catcgtcgtg tacgtaacaa tatctctggt actgctgagc gcccacgctt
    87961 gaacgttttt cgttctaaca aaaacatcta cgctcaaatt attgatgacg tagcgggtgt
    88021 aacgctagca agtgcctcta ccttggataa agaaatttca ggtggaacaa aaacagaagc
    88081 agcacaagct gtcggtaaac tagttgctga acgtgcagct gaaaaaggca ttaaagtagt
    88141 agtctttgac cgtggtggat acctttacca tggccgtgtg caagctttag ctgaagctgc
    88201 tcgcgaaaat ggactagaat tttagaagaa ggaggaatac cattcatggt ttatatcgat
    88261 ccaaaacatt tggaattaga agaccgcgtt gttgcaatta accgtgtaac aaaagttgtt
    88321 aaaggtggac gtcgtctacg ttttgctgct ttagttgttg tcggtgacaa aaacggacac
    88381 gtaggatttg gtacaggtaa agctcaagaa gttcctgaag caatccgtaa agcaattgaa
    88441 gatgcgaaga aaaacttagt tgaagtacct atggttggtt caacaatccc acacgaagta
    88501 atcggtgctt ttagtggtgg tagaatccta atgaaacctg ctgtagaagg ttctggggtt
    88561 gctgctggtg gaccagttcg tgccgtatta gaattagctg gggtagcaga tatcacttct
    88621 aaatctttag gctcaaatac accaatcaac gttgttcgcg caacagttga aggtttgaaa
    88681 caattgaaac gtgcagaaga agttgcagaa cttcgcggca aatcagttga agaattaatc
    88741 ggataaggag gacaacaata atggctgaat taaaagttac tttaaaacgc agtattatcg
    88801 gacgtcctca aaaccaacgc gatacagtta aagcgttagg tcttacaaag attaacagtt
    88861 cagtggttaa gccttctaat gaagcaatta aaggcatgat caatactgtt tctcacctag
    88921 tggacgttga agaaatttaa tttagaaaaa tcataactag aacattaagg aggtgccaaa
    88981 cctatgaaac ttcatgaatt aaaacctgct gaaggttcac gccaagtacg taaccgtgtt
    89041 ggtcgtggta cttcatctgg taacggaaaa actgccggac gcggacaaaa aggacaaaaa
    89101 gctcgttcag gcggcggtgt gcgtttagga tttgaagggg gacaaacacc attgttccgt
    89161 cgtttaccaa aacgaggatt cacaaacgtg aaccgtaaag actatgcagt cattaatctt
    89221 gatgtattga accgctttga agacggagct gaagtaactc ctgttgcttt agttgaagct
    89281 ggaatcgtga aaaacgaaaa agctggaatc aaagtattag ctaatgggga actaaacaag
    89341 aaattaactg tgaaagcagc aaaattctct aaagcagctc aagaagcaat tgaagcggct
    89401 ggtggatcaa tcgaggtgat ctaatgttta gactattaaa agatgctttt aaagtaaaag
    89461 acattagatc gaaaatccta tttactgtat ttgtgttgtt tgtatttcgc ctaggtgcac
    89521 atattactgt accaggcgta aatgctgctt cattgcaaaa cctttcttct ttgccatttt
    89581 tcaacatgtt gaacttggta agtggtagtg cgatgcaaaa cttttccatt ttctcaatgg
    89641 gggtttcacc atacattact gcttctatcg tcattcagct tcttcaaatg gacatcgtgc
    89701 ctcgatttgt tgaatggtcg aaacaagggg aagttggtcg taaaaaactg aatcaagcga
    89761 ctcgatatct gacattagta ttggcattta tccaatctgt cggtatcact gctggattca
    89821 atcaatacgc tcaattaggt ttcgtgaata atcctaacgt agcaacttac gtaacgatcg
    89881 gtttgattct aacagccggt acgatgtttg ttacttggct aggagaacag atcacagaaa
    89941 aaggtatcgg aaatggcgta tcaatgatca tttttgcagg tatcatttct agattgcctg
    90001 aaagtatcag agaaatttat gaagattact ttataaatat tgatccttca gacatatgga
    90061 aatctgctat ttttgtggcc attttactag tagcggtctt gttgatcgtg acattcgtaa
    90121 catttttcca acaagctgaa cgcaagatcc cgatccaata tacgaaacgc gtagctggcg
    90181 cgcctacaag cagctatctg ccgttgaaag taaatgcagc tggagttatt ccagttatct
    90241 ttgctagttc gtttattgct acgccaaatg ctgttttaca agcattgagc ggtagattcg
    90301 gttctgaaaa ctggtacaaa gtgatgatgg agatctttaa ctataataca gcacctggtg
    90361 ctacgattta tacgattctg atcgttgcct tcactttctt ctacgccttt gttcaagtaa
    90421 accctgagaa attagcggaa aacttgcaaa agcaaggaag ttatatacca agcgtacgcc
    90481 ctggtaaggg gactgaagag tatgtctcaa gattactgat gcgtttaagt acagttggtg
    90541 cagtcttcct tggtttagtg gcattgcttc caatcattgc tcaaatggtt tgggatcttc
    90601 cacaatcaat cggattaggc ggtacaagct tactgatcgt tatcggtgta gctttagaaa
    90661 ctgcgaaaca gttagaaggc ttaatgctga aacgtaaata tgttggattc attgagtaag
    90721 aaagcgtgtt gaggtttccc ctcaacacac gttctcacac atttattagg agggaaaaca
    90781 atgaacctca ttttaatggg gctgccaggc gcaggtaaag gaacacaagc tgaaaaaatc
    90841 attgatgctt atggtattcc gcacatctca acaggagata tgttccgcgc agcgatgcaa
    90901 aacgaaacag ctcttggcct ggaagcaaag tcttatatgg ataaaggtgc attagttcct
    90961 gatgaagtaa caaatggaat cgtgaaagag cgactagctg aaccagatac agagaaaggc
    91021 ttcttattag atggctttcc acgtacgcta gatcaagcaa aagctctgga cgcaatgcta
    91081 aaagatttga ataaaaaaat tgatgctgtc atcgatatcc atgttggtga agaaatcttg
    91141 gtcgaacgtc tagccggccg atttatctgc agcaattgtg gagcaactta ccataaaatt
    91201 ttcaacccta caaaagttga agacacatgt gatcgttgcg gtgggcatga attctatcaa
    91261 agagaagatg ataaacctga gacggttaaa aatcgtctgg ctatcaacat caaaaatagt
    91321 gaaccaatct tggcttatta taaagaacaa ggtttgctaa acactattga tggtgctcgt
    91381 gaaatcgatg ctgtatttgc agatgtacaa aaaatcattg aaaaatagca cgattgcccg
    91441 tagccgactt gcattatgca gttactcttg tcaagttcaa taaattatga tagaatatgt
    91501 cagtccgact tctagagaat cctctagatg atccattttg agaattttga ggtgggaact
    91561 gcagtttccg ccattttatc gtgtgaaaat gcgaaacaag tacaaggagg tactgtgcgt
    91621 ggcaaaagaa gatatgattg aagtcgaagg tacagtcgtc gaaactttgc cgaatgcaat
    91681 gtttaaagtt gaactagaaa acggacacca agttcttgct actgtttcag gtaaaattcg
    91741 tatgcattac atccgtatct tacctggtga caaagtaacg gttgaattgt ctccatacga
    91801 tcttaaccgt ggccgtatta cttatcgctt taaataattg tactccgtaa aactacagga
    91861 ggtattatca tgaaagtaag accatcagta aaaccaatgt gcgaacattg taaagtaatt
    91921 cgtcgtaaag gacgcgttat ggtgatttgc ccagcaaatc caaaacataa acaacgtcaa
    91981 ggataattgg aggtgctata aatatggctc gtattgcagg agtagatatt cctcgtgata
    92041 aacgtgtagt agtttcactt acttatatct atggtattgg taacactact gctaaaaaga
    92101 tcttagctga tgctggtgta tctgaagatg ttcgcgttcg tgaattaacg aatgaacaaa
    92161 cagatgctat ccgtgcagaa gtagataaat taaaagttga aggggatctt cgtcgtgaag
    92221 tgaacttgaa catcaaacgt ttgatggaaa tcggttctta ccgtggaatc cgtcatcgcc
    92281 gtggattgcc tgttcgtgga caaaacacga aaaacaatgc acgtactcgt aaaggcccag
    92341 ctcgcgctat cgctggcaag aaaaaataat tcttaagtga aggaggttaa aacttcatgg
    92401 cagcaaaaaa agtgaatcgt aaacgccgtg tgaagaagaa tatagaagca ggtattgcac
    92461 atatccattc tacattcaat aacactatca tcatgatcac tgatactcac ggaaatgcat
    92521 tagcgtggtc atcagctggt tcattaggtt tcaaaggaag caaaaaatca actccttttg
    92581 ccgctcaaat ggcagcagaa actgctacaa aagcagcaat ggaacacgga ttaaagactg
    92641 ttgaagtaac agttaaagga cctggttctg gacgtgaagc agcaattcgt tcattacaag
    92701 ctacaggttt agaagtgact gcaattcgtg acgtgactcc agttcctcat aatggtgccc
    92761 gccctccaaa acgccgtcgt gtttaatgag tgccgctcat tttgagtttt atcagtaacg
    92821 tcattgaaca agacactttt cgttttgaaa ggggtaaaga taagaatgat tgagttcgaa
    92881 aaaccaagaa tcgcaaaaat tgatgaagaa aaagattatg gcaagttcat cgttgaacct
    92941 cttgaaagag ggtatgggac tactttaggg aattccctac gtcgtatttt attatcttct
    93001 ttgccaggtg ctgccatcac taatattcaa atcgatggtg tactgcatga attctctacc
    93061 atcaaaggtg ttagagaaga cgtcactcaa atcatcttga acattaaagg cttagcgctg
    93121 aaaatgtatg gccaagaaga aaaaaccctt gaaatcgata ttaccggacc tgctacagta
    93181 actgctggcg atattatcgt tgatagtgat gtagaaattc ttaacaaaga tatgtacatc
    93241 tgtagtgtct ctgaaggagc tacgttccat gctcgcttaa cagtgaaacc tggacgtggt
    93301 tatgttcaag cagatgaaaa taaaaaagaa gatatgccaa ttggcgttct tccagtcgat
    93361 tcaatctaca cacctgttcg tcgtgtgaac tatcaagttg agaacacacg tgttggacac
    93421 cgtgaagatt ttgataaatt gacgatggag atttggacag atggttcaat tgaaccgttg
    93481 gaagcaatga gtttgtctgc gaaaatcatg actgaacatt tggatatttt tgtgaactta
    93541 actgatgaag caaaaaatgc tgaaatcatg gtcgaaaaag aagaaacaca aaaagaaaaa
    93601 atgttggaaa tgacgatcga agagttagac ttgtctgttc gctcttacaa ttgtttgaaa
    93661 cgtgcaggaa tcaatactgt acaagaactt acaaataaat ctgagcctga aatgatcaaa
    93721 gtccgtaact taggacgtaa atcattagaa gaagttaaag caaaattgca cgacttaggt
    93781 ttaggtttac gtaaagaaga ttaaaacctt ttacgaagga gggaaaccaa cgtgagttat
    93841 cgtaaactag gacgcacatc tagccaacgt aaagcgatgt tgcgtgattt aacaactgat
    93901 ttattaatca acgaacgtat tgtgactact gaagctcgtg cgaaagaagt tcgctcaact
    93961 gcagaaaaaa tgatcacttt aggtaaacgc ggagatttgc atgcacgtcg tcaagctgcg
    94021 gctttcgtac gtaatgaagt tgccagcgtg cgtgaagaaa atgaggacat cgtcattgaa
    94081 tcagctttac aaaaactgtt caacgatatt gcacctcgtt acgcagaacg tcaaggcgga
    94141 tacacacgca ttttgaagac agaaccaaga cgcggtgatg gtgcaccaat ggttgtctta
    94201 gaacttgtct aaaatcacac taataacatc actttataga tgattctttt agagtgttat
    94261 gatgttggaa gatatttttc cgagtctagc tcagcgctgc tcctcaagcg aatatcgctt
    94321 ggggagtaag cactcatcat aaagtgtttt tttatacctt caattacctg tcatgacaga
    94381 tatgtttgaa ggcataaaaa aacattttaa gcgagaaata attgaaaatt ttgtcttttt
    94441 ttgatagtgt tagtaggaac tttaggatga agaaggagta atcatggagc caattattga
    94501 attagaaaag ataaattata aataccagcc agatgatctt cgccccgcat tgaaagatgt
    94561 ctcctttaca attgataaag gtgagtggat cgctattatt ggacacaatg gttcaggaaa
    94621 atcgacactt gccaaaacga tcaatggatt gcttctgcca gaatcaggga tcgtgaaagt
    94681 gggaaatcaa atattggatg aagaaaatat ttggacgatc cgacagatgg ttggaatggt
    94741 ttttcaaaat ccagacaatc agtttgttgg ttcgacagta gaagatgacg ttgcttttgg
    94801 tcttgaaaat caagggattc ccagagaaga aatgctagtg cgtgtgaaag atgcacttga
    94861 gaaagttaga atggctgagt ttgcttcacg cgagcctgct cgtttatcag gagggcaaaa
    94921 acaacgtgtt gccattgccg gcgtggttgc cttacgacct gatatcatta ttttagatga
    94981 agcaaccagt atgctagatc cagaaggtcg tgaagaagtg atctctacga tcaagaagat
    95041 caaagaagaa agtcaattga ccgttatatc tatcactcat gatattgatg aagcagctaa
    95101 tgccaatcgg atactagtga tgagacaagg cgaacttgtc cgtgaaggta caccaaaaga
    95161 aattttttct gctggtcctg aactgatcga cttaggtcta gatctaccat ttcctgaaaa
    95221 actgaagagc gcactgaaag aacgtggggt tgatgtgccc agtgaatata tgacagaaga
    95281 aaggatggtg gattggttat ggacatccgt tttgaacaag tagacttcac ttatcagccg
    95341 aatacaccat ttgaacaaag agccttattt gacatcaata tgacgatcaa agaaaacagt
    95401 tatactgcat tagtagggca taccggaagc gggaaatcaa ccttacttca gcatttgaat
    95461 gcgcttgtta agccaacaag cggtacagtc catattggag aacgagatat tcagccggat
    95521 acggataata agaatttaaa gcccatccga aaaaaagttg gcatcgtctt tcagtttcca
    95581 gaagcacagc tattcgaaga aacggtagca aaagacattg ctttcggtcc taaaaacttt
    95641 ggtgtcagcg aagaagaagc actagtccta gcaaaagaaa cattagaaca agttgggctg
    95701 gatgaaagct atttggaacg ttcgccattt gaactttcag gagggcaaat gcgtagagta
    95761 gcaatcgctg gtgtgcttgc catgaggccg gaagtacttg tattggatga accaacggca
    95821 ggacttgatc cccagggcag aaaagaaatg atggagatgt tttggcgtct tcataaggaa
    95881 cagcagatca ctattgtatt agttacgcat ttaatggatg atgtagccaa ttttgcagat
    95941 tatgtctatg tgttggaaaa gggacgaatc gttaatagcg gggagccgca agaggtcttt
    96001 caaaacattg aatggctaaa agaaaaacaa ctaggcgtac ctactgccac cgagtttgca
    96061 gaagaattaa tggctaaagg gatgaacttt gctaccttgc ctttgacagc tgaagaatta
    96121 gcagacgcta tcgtccatta tgctggagga aatgcccatg atgaataaat tgatatttgg
    96181 tcgttatatg cctggagatt ccttgatcca tcgattggat ccccgagcta aattattagc
    96241 cagtttttat tttatcggaa tcattttttt agcaaataat tgggaaacgt accttttgtt
    96301 ggcatttttc acattacttt ctgtcttctt gtcaaaagta gatttgaaat tttttatccg
    96361 aggcattcgc ccattgatct ggctaatcct cttcactgta gctttgcagg tcttgtttac
    96421 aagtggcgga gaaacttatt ggagttgggg tgttttccat atcactgaat ttggtgtgat
    96481 gaacggcctc tttattttct gtcgattcgt gttgatcatt tttatgtcga ctctactcac
    96541 gcttactaca ccgcctttgg aattatcgga tgcgattgag tacttgcttc gtccattgaa
    96601 agccgtacgg ttcccagtcc acgaaatttc attgatgctg tcgattgctc ttcgttttgt
    96661 gcctacattg atggacgaaa cagaaaagat catgaacgct cagcgcgctc gcggtgttga
    96721 ttttggtgaa ggaaacctag ttcagaaaat gaaagcagtc attcctttgc tgattccttt
    96781 atttgtcagc agcttcaacc gtgcggaaga tcttgcgact gctatggaag caagaggcta
    96841 caaaggtggg gaaggaagaa cgaaatatcg tgtattgcat tggcataata gagacacgat
    96901 ggttatcatt gcttttgtat tattaactgt gctactgatc tttttaagag gataaacgtt
    96961 cagtgggccg ctatctattc ttttcttgct gatctgtttg caagaaagga tgcaagcagt
    97021 gtatgacaag aaatattagg gtctgtggca gactaaggtc acaggcctct ttcttttatc
    97081 tgaaaagaaa gaacgaaaaa attttataga aaaatcatta ttccagataa ccttttagga
    97141 acaaaggaga gaaaaacatg gtacgttaca aagcaatcat tgcgtacgac ggaacaaatt
    97201 ttaatggatt ccaaaaacag ccaaatgggc gtactgttca agaagaagta gaaaaaacat
    97261 tacaaaaaat ggcaaatgga aaagaaatca cggtctttgg ttcgggaagg acagatgccg
    97321 gagtacatgc gatcgggcaa gtaatccatt ttgattatcc agaggagcgt ccgttagaac
    97381 gaatgcgttt cgcgctagat acccagtcac cagaggatat tgctgtaaga caagtagaaa
    97441 ttgtttcaga agacttccac gcaagatatt tggtcaaaga aaagacgtat caatttcgag
    97501 tggatatagg gaaaccacgc agtccttttc gacgccatta tgcaagttat tttccttacc
    97561 cacttgattt ggaaaaaatt cagcgggcgc ttcctgattt attagggact cacgatttca
    97621 cctctttttg tgcatcagga agctcgatag aggataaaat acgtacgatc tacgaggcta
    97681 agatggaggt aaatgaaaca aaagacgaat tgttgtttac atttagggga aatggcttct
    97741 tgtataagat gatacggatc ttagtaggaa cgcttttgaa aattggcaat ggccgattgc
    97801 ctgaagatag tatcccagat attattgcga aaaaagatcg taatgcagca ggacctacag
    97861 cacaccctga aggactttat ttgtatgaag tgaaatatga ataagaggtt atgatagaag
    97921 tggtcagctt caagaaataa gaaggtattt acgaaaatta cttctcaaaa ttttgcaaaa
    97981 tttcggctta ttttcgaaga agctacttct ggaacaccgt ttaaggaaga ggtcgtgaaa
    98041 tcagcgtttt gacctgagta ttagagaaac aaacgggaaa atagctcctc atattttgcc
    98101 gtttgttgag ctaataccga aggtcagctg attgaacacc gtttaagaaa gaggtcgtga
    98161 gcctgtcatt taactctgag tcacaaagag caatttcaaa aaacagcttc tcatctttga
    98221 tgaatatcgt gacttgtgga cgaggcgttg ataagtgaat catctttttg ttacctattt
    98281 tttctgtaac caaaaaacga tggaacgttg ttttgattgc ccttggtgcg gacagtctga
    98341 acaggttcca tcgtttcttt attttctacg tcttcttctg tgtgtgtttc gtggttgttc
    98401 ttctattgct ggatcaatcg tgccataaaa ggggcgattg cggtcaaggt accagacata
    98461 aagaataaac aatgcaatac ataggacaaa aaggattgca cctatcgtaa atccttcagg
    98521 caagtaactg aaagtgacag tatgtttacc tgctggaact tttatcatca agaatgcgtc
    98581 tttgaaattg ctgaccttga ctggtttccc atcaatttta gctttccatc ctttgtcata
    98641 aggaatagtt gtcaccaaca tggaatcttc agcggtattt acagtcccag aagcttttct
    98701 gccagtggct tccatttcga cacctttttc tttgatctga ttcattgcgg cttgataggc
    98761 tacaacatct agaccaacga ctttaggctc catgaaactt atttctttcg tcccataaaa
    98821 acttgcagta aatgtcactg ttgtctcttg aggataatag ccaagatcat agtattgacc
    98881 agaaatgttg atttgcgttt ttcgcgatgt accattgaca gtgatcgtcg cactagaact
    98941 ttctaattgc gcaaaattgg ttgggaacaa acttaagtaa gcttgtgtat ttgcaggcac
    99001 atggacttcc caagtgagct cttttggctg gttatctgct gtttctgagt aagtgacgcc
    99061 agtcgttgtc tttgtgatcg tcgtattcaa ctgattcttc aaagtaggtg tatagaatgt
    99121 aaaatactgt tcatttagac cagacaatgt attgatcaag tttgtctgac tggtcaaatt
    99181 atctgtcact ggctgctcaa catcattaac ggacaacggt gcagtaaatg ctagtggcaa
    99241 tgcattgaca ttctgataca gtgtatagtc gccgctttga ccagcttggc ggaagccata
    99301 tttactgaac gtgctttcgt ttttagaagt gttatatttg attcctgtaa acccatccat
    99361 cagcaaagta ttattgttat aacggatatt caaatttgtc cctcttgaac ggaaacctaa
    99421 tttatccagg taagaggaag aattacgatt tcttatagaa gaaaacaaac tgataccact
    99481 gtaaccatag ttgatcgaat cgtttgcaga tactggatcc agattttcca agcggtaaaa
    99541 cgagtcggaa tctttttttg tttcatttac aagagctttc aagtcaggat aaggatcagt
    99601 atataaactg cgggaagcat aattccaatc atcaagaatg ccatggatca tactgttcgt
    99661 attgaccagt gcttcagcag acatgatcaa taataacaat atactcagat gattgaatga
    99721 aagtttttta tgctgataaa atcccacagc aaaagcataa atccctaaga aaaccactgt
    99781 caatacaaag gaagtcatcg tcacataggt gtagcttcct tcaggtttga tgccccatgc
    99841 caccgcaaag agagcagcta cgaccaaaat gattcctaac aacagcccac gatcgtcttg
    99901 ttctatcttt tcccatcctt ttcctgcaag caggagcact aagaaagaga acagataggc
    99961 ataacggaat aaaaacatat tcggtgcatg cataccatgc cagaacaaat tcaatggaac
   100021 aagataaaaa cttgcgataa gtatggcgaa aagactgccg tacaaaaatt tatttttcaa
   100081 cggtactttc cgactggcaa aataaaacag acagaggact aatggtagca gacctgcgta
   100141 aacgaacgga atcgatccgt attttgtcgt gtcataaaca ccaatcatat ttttcatgat
   100201 tagatccaga taagaagtcg cttctgtttt caacgtagtg atctgactca gtgcctcgcc
   100261 atttgaccga agatccagca ctgctggcaa tacaatgatc attgaagcgc cgcctgccag
   100321 taaagaagtg ataccataag gaacaatcgt ttttttatat tctgaccagt ttgtcaatag
   100381 acgggcgata aaatataaga aagaaaatac gccaatcata aaacccatat aaaaactgga
   100441 taaaaacaag agtaaataac tgataaataa aagtttcggc cgtttaagat ccataacacg
   100501 atgaatcccc aaaatcacta atggaagata aaaaaatgca tccagccaca tgatgatctc
   100561 cgaatgtgca gtgataaatg agatcaatgc gtaactgacg ctaagtgcaa catgccccca
   100621 gcgaggaatc ttgaacgtac gtgcaagaaa ccaaaaagcc aatccggcac agccgacctt
   100681 aagcaaagtc agaacataca gtgcatctgg catcatctgg tttggaaaaa agaacaccag
   100741 tggcgtgaag atcccgccta gatagtaaga aattaaagat aaataattca atcctagaga
   100801 agcattccat gtataaaaaa tactttgctt tccaagaaga acatttcgga agctggcatg
   100861 aaaattagaa aactgtgaaa aggcatcact tgccaaaata cttctgctgc ttccaggata
   100921 gattccgata cttagataaa caagtgctaa aatcaaaaac ggaatcagga aactagctgc
   100981 tgcgtagcgt ccgttttctc taaagaatga ctttaaattt tttttcatat ttattttcca
   101041 ccaaatttct atgaagttgt attcagttta tcatatcctt gtttttctct gcttaaaaag
   101101 agtctagttt tcacaaaaaa ataaaattta gaataaataa cttcataatt tgttcgtata
   101161 acaaaaataa acgcaaaaaa agggtaggaa tcaaaagtcc cacccttaaa aatttttatt
   101221 aaataaaaaa ccgttcacta tctgaacggt ccaagtatca ttcaattaaa cgcgttcaac
   101281 ttttcctgat ttcaaagcac gagttgacac ccaaactttt ttaggttttc cgtcgaccat
   101341 aacgcgaact ttttgtaagt taggtttaac agtacgtttt gttgagttca tagcgtgtga
   101401 acggttgttt ccactttttg tcttgcgacc tgtaaagtaa caaacttttg ccatggtaat
   101461 ttcctccttt gccttgattt ggagcaatag aataattcag ctcataccag actaacatat
   101521 catatagaat gggaatttgc aagtacattt tcatagatac aattgacaat tgagaagaat
   101581 aattgtaaat taaacaaggt tatacctgaa attttgcaag gtttttgagt actttgggta
   101641 actgcctttt atttcaagtt gcgctatgat aaaatatgat agaagaaaaa tgggagtttt
   101701 ttacccgtta aggaggctca ttcatggctg taaaaattca aacgtcagct ggaaccattg
   101761 aaattaccaa tgatgtaatt gcaacagttg ttggtggcgc cgcgacagat gtgttcggtg
   101821 ttgtaggaat ggccagcaaa aatcaaatta aagataatat tactgagatt ttgcgtaaag
   101881 aaaattactc aagaggagta gttgtccgcc aagaagataa tggtattgct gtagatgttt
   101941 atacgattat cagctatggt acgaaaatct ctgaagtttc ccgcaacgtc caagaaaaag
   102001 tgaaatacaa tctagaggca ttattaggcg taactgccaa ttcagttaat gtctttgtac
   102061 aaggtgttcg tgtactgcca gactaggcag gagactggct ggtaactcag cagtcgatct
   102121 gaaggaggat tatctaggtg agtgtaacag aaataagtgc aagccagttc caggaaatgg
   102181 tccaggcagg tgcgaatcgt ctgcaagtaa atgcagaata cgtcaattca ttaaatgtat
   102241 tccctgtgcc agatggcgat acgggaacaa atatgaatct atctatgact agtggagcta
   102301 aggcagtagt agattcaacc tcagaaaaag taggagaatt agcagcaatg ctttcaaaag
   102361 gattgctgat gggtgcgcgc ggaaattccg gcgttatttt gtctcaattg tttcgtggat
   102421 tttctaagca aattccagat gttgtctcat taaatgcttc tgatcttgct gcagccttca
   102481 ctcatggagt tgaaactgcg tataaagcag taatgaaacc agtagaagga acgattttga
   102541 cagtagctag agaagcagcg aaagctggag aaaagaaagc aaaaagtact gatgatgtcg
   102601 ttgaagtaat gacagctgtt gtaaaaggag caaagcgtgc tttagctaaa actccagact
   102661 tgcttccagt cctaaaagaa gtcggtgtcg tagacagtgg agggcaagga ctgctgtttg
   102721 tttatgaggg ctttttaagt gcattgaatg gagaattcca agcggatgaa acatatgaac
   102781 cttctccagc agaaatggat gatatggtca atgcagaaca tcatcgcagt gtccaaggtc
   102841 aaatggcgac agaagatatc cattttggtt actgtacaga aatcatggta aaaatcggag
   102901 aaggacctac agtcgatagt acattcgatt acgaagaatt ccgtaactat ttagatggta
   102961 taggagattc tttacttgtg gtcaatgatg acgagatcat caaagtccac gtgcatacag
   103021 aaaacccagg agaagtcttg aattatggac aaaaattcgg ttcattagtc aaaatcaaag
   103081 tcgacaacat gcgcttgcag catgagacga ttttggaaca cgatgaagaa gtgaacgagt
   103141 ttgcgaaaaa agaaatacca cgtatcccgt atggtatcgt agcgatcgct gctggtaaag
   103201 gcgtccaaga gctgtttgaa agtttaggcg ctaattatgt tatcagtggt ggacaaacaa
   103261 tgaatccaag tacggaagac attgttaaag cgattcaaga agtaaacgca gataaagtga
   103321 ttgtcttgcc aaacaataag aacatcttca tggcagctga tcaagcagca gaagtagcag
   103381 atatcccagt agcagttgtt ccttcaagaa cgatttccca aggattgaca gctatgcttt
   103441 cattcaatga tcaagcttct ttagaagaaa acaaagaaac gatgacagaa atgttgtcta
   103501 gcgttgtgag cggtcaagtc actcacgcga tcagagatac ctcaattgac ggtgtagaga
   103561 tcaaagaagg agactttttg ggcatgatcg atggaaaaat cctgatctct aacccagata
   103621 tcacagcaac agcgttaagt acactagaac aaatgatcaa tgaggacaca gagatcgtaa
   103681 cgatcttggc aggtgatgaa ggaacagttg aacaagcaaa tgaatttgct gagaaactaa
   103741 cagaaaaaca tcctgatttg gaaatcgaga tccaccaagg agatcagcct gtctatcctt
   103801 atctattttc tgctgaataa tttctgtgtc agaatatctt tctaacacag tattcattca
   103861 taaaaggcct tcggttagtg atcaggtatg atcgctgacc aagtcctttt tttgttaaag
   103921 gagggaggaa aaatttatgc gttctttaga tgatccaatc actatgctgg caggagtcgg
   103981 agaaaaaaga gcagctagtc ttgccagctt gggcatccaa acgattgaag acttactgac
   104041 ttattatcct tttcgctacg aagatattca ggaaagaaat ctaaacgaga tccaggatca
   104101 agaaaaggtt actttgaaag gaatcgtagt ctcgcctcct gtgatgaatc gatttggtta
   104161 taaaaaaagc cgattgcaat ttcgtatgat gcaagaacat gatgtgttca acgtttcttt
   104221 ttttaatcaa ccttatctaa aagaaaaagt cattttatcg gaggaaatcg ccgtatacgg
   104281 taaatgggat gcaaagcgta aagccttgaa cgggatgaag attttaggtt ctcaaacaat
   104341 ggatgacttt tcgccgatat atcacgtcaa caaatcaatt cgtcaaacga cattagttga
   104401 tctaatcaaa aaagggtttc aagaatacgg cacattgatt gaagaaaatc tgccaaacaa
   104461 ccttgtggag aaatatcgac tgcttgaccg agcttctgct gtaagaagta tgcattttcc
   104521 aaaagaccac gaagaaaacc atcaagccaa acgacgtgtc gtttttgaag agttcttttt
   104581 atttcaaatg cgtcttcaag gattgaaaaa agcagaaaaa gcagaaacga atggtttgga
   104641 gatcctttat gatgtccaaa aattgaaaca atttactcaa aagctacctt ttgaactgac
   104701 aaatgcacaa aaacgtgtaa cgaatgaaat ctgtcgggat cttcgcagtc cgcagcatat
   104761 gcagcgactt ttgcagggag atgtaggtag cggaaaaaca gtggttgccg cgattgcgtt
   104821 atacgctacc gttacagcag gtttccaagg tgcgttgatg gtgcctacag aaatcttggc
   104881 acaacaacat atggaaagct tgcaacagct gtttgatccc aatgaagtaa ccatcgcatt
   104941 gattacgggg tcaacgaaag caaaagaacg acgtgagctc cttgaaaaac tagagcaagg
   105001 ggaaattaac gtcgtgatcg gcacacatgc attgatccaa gatggagtcg aatttcagaa
   105061 tttaggtcta gttattacgg atgagcagca ccgttttggc gtgaaccagc ggaaagtact
   105121 tcgtgaaaaa ggctggcgac cagatgtctt atttatgaca gcgactccga ttcctagaac
   105181 attagctatt acagcatatg gtgagatgga tgtatctatc attgatgaac ttccagctgg
   105241 acgtatcccg atcgaaacac gctgggtaag aacacctcaa ttggacagtg tactggattg
   105301 gacgaaaaaa gaactggcaa gaggacatca aatgtatgtc atctgtccgc tgattgaaga
   105361 atcagaagca ttagatgtaa aaaatgcagt ggaaatctat gaaaaacttc gtgaactatt
   105421 tgcaccaaaa tatgaagttg gcttgttaca tggtaaaatg aagaatcagg aaaaagaagt
   105481 aatcatggaa gccttcaaag acaaccagat gcagatatta gtttcgacta ctgtaattga
   105541 agtaggggta aacgtgccga acgcgaccgt catgctgatc atggatgcgg atcgatttgg
   105601 attggcacag ctgcaccaac ttcgtggacg tgttggacgc ggaagtgatg cttcctactg
   105661 tatcttagtt gctaatccta aaaatgaact aggtgtggaa cggatgaaaa tcatgacaga
   105721 gaccaccaat ggttttgtac taagcgaaaa agatctggaa ttacgtggtc ctggtgaagt
   105781 atttggcttc cgtcaatctg gtctgcctca atttgcgatt gctgacttgg tgacggatgg
   105841 aaatgttttg gaggtagcca gagaagaggc tgcagccctt tggcaaataa aggattggca
   105901 gatgcttcct gagtatcagc ctttagcgca aagcctccaa atagaaaatc aggataatcg
   105961 ttatttcgat tagcagactg tgctatactt tatactgatg acggaaaaag gagtggaaac
   106021 aatgaaaatt gccgtagatg caatgggcgg agatcacgca cctcaagcaa ttgtagaagg
   106081 cgtggcttta gcgcagcaag attttccaga agtagaattc ttactttacg gaaaagaagc
   106141 agaaatcaag aaatacttaa caaatgaaaa aaacatcacg attatccata cagacgaaaa
   106201 aatcaatagt gatgatgagc cagtaaaagc aattcgacga aaaaagactg catcaatggt
   106261 ccttgctgca caagcagtga aaaacggtga agcagatgct gtattttcag cagggaatac
   106321 aggcgcgcta ctagcagcag ggttgttcat cgtaggacgt atcaaaaata tcgaacgccc
   106381 tggcttgatg tctaccttgc cagtagtagg gaaagaaggt gccggtttcg atatgctgga
   106441 tcttggcgct aacgcagaaa acaaaccaga acatttgttg caatacggta ttttaggttc
   106501 tttttatgca cgtaaagtcc gaggtatcgg acgtcctcgt gtcgcactct taaacaacgg
   106561 aacagaagca acaaaaggta gtgaagtgac gaaaaaagcc tatgaactcc ttcagaatga
   106621 aacaagcttg aattttattg gaaacgtaga agctcgtgag ctactcaatg gtgtggctga
   106681 tgtagtggtc acagatggat ttacaggcaa cgctgttttg aaatctattg aaggaacagc
   106741 aatgaatatg atgaatctat taaaatctgc tattctaaat gaagggatca aaggaaaaat
   106801 gggcgctatg cttttaaaag acggcttacg ttctttgaaa gcagaaatgg attattccaa
   106861 acatggcggt gccgttttgt ttggcttgaa agcaccagtc attaaaactc atggagcaac
   106921 aggccccgat gctgttcgct atacgatccg ccaaatccac acaatgcttg agacagatgt
   106981 agttggacaa ttagtcgaac aatttgaaaa aagcgaagaa tagtatttgg atatctgaag
   107041 cgatccgttc cattgaaaaa aaggtggaca ttcctgaaaa atgccagtaa aattagccat
   107101 ggtgtaggta attgacaagt gtatgattct tggaggtgaa aaagttgact cgcgaagaag
   107161 tatttaacaa agtagcgaaa attatttcaa atcattttga gatagatacc gataaagtga
   107221 cggatgaatt gaacatcaaa gatgatttaa aagctgattc aattagtatt atggaattcg
   107281 ttttagagct tgaagatgaa ttcggtacgg aaatttcaga tgaagacgct gaacaaattg
   107341 aaacagtcgg tggcgcagta gattatatca gcagccatct taaataattt caaataaaag
   107401 caaagaagga taaaaagctg catgcagctt tttatccttc tttttttaat ctttttgaca
   107461 cgtaaaagtc atttttctga taattctggc gataaacaga aattatgttg caaagtaaag
   107521 cggttttcta tataattatt aataattcat tacacaaaga taagaataac ctttgttata
   107581 aaacgattta ttctgtgtaa tgtccttttt tattaagaaa aacttccatt taggaagcag
   107641 agaggggtat tcgattgtcc gataaccaat tattagaagt tcagaaccta catacaggat
   107701 tccgactcaa agatgactat tacgatgcag tagatgacgt ttcatttact ttagacaaaa
   107761 acgagatttt agcaatcgtt ggggaatctg ggtgcgggaa aagtaccttg gctactacga
   107821 ttatgggatt acttgatcct aataacacaa aaattacagg tgagatttta tataacgatc
   107881 tgaatttaat cgacctgaac gaaacgctct ataataaaat ccgcggaaat gatatcggaa
   107941 tgattttcca agatccgttg tctgcattaa atcctctcat gagaatcgaa gaccagatca
   108001 aagaaggact ttcctatcac acaaagatga atgcagaaca gcgtcaagct cgtgcactag
   108061 aattgctaga acaagtaggg attcctaatc ctgcgagagt tggacgccaa tatccccatg
   108121 aactatcagg cggtatgaga caacgtgtca tcatcgcaat cgcaatcgcc tgcaaacctc
   108181 caatcgtcat tgcagatgaa ccgacgacag ccctagatgt aaccatccaa gcacagattc
   108241 ttgatttact gaaagacctt caggaagaaa caaaaacagg gatcatcttg atcactcatg
   108301 acttaggagt cgtagcagaa atggctgatc gagtggcagt gatgtatggc ggacagttcg
   108361 ttgaagtagc aggtgtaaaa gaactgtttg atcatcctaa gcatccttat acacgctctt
   108421 tactgaactc tataccacaa gaaggaaatc atgatgcaga actccatgtg atcgaaggtg
   108481 tcgttccttc tctgaaaaac atgcctcgta aaggttgtcg gtttgcacca cgtattccat
   108541 ggataccagc aagcgatcat gaagaagagc ctatccttca tgaagtcgca ccgaaccact
   108601 tggtacgttg ctcctgctat aagcatttcc actttagaga cgaaaaagga gaggtgtaga
   108661 tgacagaatt aatcacaatc aaagacctga aagttcatta ccctattcgc agtggattct
   108721 tcaatcgagt aacggatcat gtatatgctg tagatggtgt ggattttatt atcgaaaaag
   108781 gaaagacata tggtttagtg ggagagtctg gctctggaaa atctactacg ggaaaagccg
   108841 ttgtgggatt agaaaaggta acagccggac aaatcatgta tgaaggaaaa gatgtaacga
   108901 agcgaagcaa ccgcaaaaaa atgggttata acaaggatgt gcagatgatc ttccaagatt
   108961 caatgtccag tttgaatcct aaaaagcgag tgttggatat cattgctgaa cccatccgaa
   109021 attttgaacg gttaagcgat caagaagaaa agaaaaaggt aaaaggactg ctagatatcg
   109081 ttgggatgcc ggaagatgcg ctatataaat atcctcatga attttcaggc ggacaacgtc
   109141 aacgtctagg agtagcccgt gctgttgcta ccaatccaaa actgatcgta gccgatgaac
   109201 ctgtatctgc tctggatcta tctgttcaag cgcaagtatt gaatttcatg aaacgaatcc
   109261 agcaagaata cggcctcagc tatttattca tttcacatga tttaggtgta gtaaaacaca
   109321 tgtgcgacaa tatcgcaatt atgtacaaag gtcgatttgt agaaatcggt acaagagaag
   109381 acatttataa tgacccgcga catatctata cgaaacgtct gctttcagct attccgcaaa
   109441 tcgatgtaga aaatagggaa agccacaaag aaaatcgacg aagagtagaa caagagtata
   109501 tccaaaacca aaaagaatac tatgatgcga ctggtcgagt ctacgatttg cgtacgatca
   109561 caactacaca caaagtggcg ttgaaagatg gaggtgcaag ctaatgtgga aaacgattct
   109621 gcgacgtgtt ttattgatga tcccgcaagt tattatttta agtgttctga tcttcttatt
   109681 agcccaagcg atgccggggg atccatttac cggtttgatc aatccaaatc aggatccggc
   109741 agtgatcgaa cagatgcgac aagcagctgg cttgaatgac ccatggtatg tccagtactt
   109801 ccgttggatc ggaaatgctt tgcaaggcga ttttggtcaa agtttcttat acaaacgctc
   109861 tgttgctgac ttgatcggcg aacggatcat caacacttta tatctatcga tcttgacagt
   109921 tgtccttact tatttgattg ctgtgcctct ggggatgctt gctggccggt atcaaaattc
   109981 aatcttggat aagattgtcg taatctacaa cttctttagt tttgctgttc ctttatttat
   110041 cttcggcttg atcatgctat ttgtttttgg ttatcgttta ggctggttcc caacaagtgg
   110101 atcacaaaca ctaggtttgc aaggtggatt tatcactcaa tggatagacc gtttgaaata
   110161 tattctgtta ccatcaatta cccaagcatt tttggcgact gccgtcacaa tccaatatct
   110221 gcgaagtgaa gtaatcgatt cgaaatcgct cgattttgtc agaacagccc gttccaaagg
   110281 ggtaccgacg aataaagtat tcagtcgaca tattttccga aatgcagcgt tgccgatggc
   110341 ttctcaaatg gggtatgaaa tcacttcgtt gattgctggt tctgtagtta tcgaaaagat
   110401 ttttggttat ccgggagtcg gaaaactatt tattgattcc atcggccaac gggactatac
   110461 cgtgatcaca tccttagtat tgattttagg aatcgcgacg ctagtgggga cattactttc
   110521 agatatcatc atgagtatcg ttgacccgcg tattcggatt caataaaacc aatcagaaag
   110581 gagaatggat cgatgagtga aaaaaacaat acagcagttc aagaaagtat tcctcctatg
   110641 gggatacgaa tgattgctcg agaatttaaa aaagataaaa ttgctatttt ttcattaggt
   110701 ttgctagtgg ttttattatt agtgatcttt atcggtgcga tgctgaccga tcaagacaaa
   110761 gtgatgtatg ttagtatctt cgacaaatac gctgcaccag gaacagtttc gacacaagga
   110821 caaaagttca ttctgggagc agatgaaggc ggacgtgatg tattaggaca attgatcata
   110881 ggtgctagaa actctgttac gatcggattt gcgatcacga tccttacttc gatcatcggg
   110941 gttggattag ggatcatctc tggctactac ggagggatca ttgacaacat cttgatgcgg
   111001 atcgttgatt ttatcatgat tctaccgatc atgctgatca ttatcgtctt cgtatcgatt
   111061 atttccagat acaatgtctg gtcctttata ttcatcatga gtgcatttta ttgggtagct
   111121 aaagcccgat tattccgaag caagacatta tctgaagcaa gaagagatta tgtcagtgcc
   111181 tcaaaaacaa tgggaaccaa tgattttaaa atcatgttcc gcgaaatcat gccgaatcta
   111241 agttcattaa tcattactaa tttgacgatg aactttgcgg caaacatcgg tatcgagaca
   111301 actttgactt tcttaggttt cggcttgccg gcaaatgtac ctagtttagg tacattgatc
   111361 ggttatgcaa gtaacggaga agtcttagtg aatcggcaat ggatctggtt acccgcatca
   111421 atccttattt tagttttgat gttgagtatc aattatgttg gacaagcatt caagcgttct
   111481 gcagatgcgc gccaacggtt aggctagtat agaagcgaag ggggaaatag gaatgaagaa
   111541 aacgattttt ggatttgcag cgctgatgtc tgctgtcgtt cttgcagcat gcgggggcgg
   111601 aggtacagat acctctggaa acaactctgg aggcaacggc aataacaaag aggaattaac
   111661 ttttccaatt gcaacaaaaa ataatgatga tgcaatcgaa gacggcgaat tagaagctgc
   111721 ggtcgcaacg gacagtcagt ttaaaggatt gttccagtgg gagttttacc aagattcata
   111781 tgatgcagct tttatggctc cttctcatga accgctattt gcaaacgatg acgatttcag
   111841 aatcacagac gacggagctg caacgcttga tctagatgaa gatacgaaaa aagcgacaat
   111901 caaagtaaaa gacaacgtca aatggtcaga tggtgaagat gtaacggcgg acgatgtgat
   111961 tttcccttac gaaatcattg ggaataaaga ttacactggt atccgttatg acgacacttt
   112021 ccgtaacatc gtaggtatgg aagaatatca tgatggaagt gccgacacaa tctccggaat
   112081 caaaaaaata gacgacaaaa cagttgaaat cgaatataaa gaagtaaacc caagcatgct
   112141 tcaatcgggt ggtggtatct ggtcatatgc agcaccaaaa catacgttag aaggtgtagc
   112201 aatcaaagat atggaatcaa gcgatcaagt acgtaaaaat ccagtgactt ttggccctta
   112261 ttacatgagt aatatcgttg caggagaatc agtagaatac ttgccaaacg agcactactg
   112321 gaatggtacg cctaaattga aaaagatcac gatgaaatct gtaccgatgg caagtgcaac
   112381 tgaagcattg aactctaaat tatatgatat gattttccaa atgccaacag atacttacga
   112441 tacctataaa gaaattgctg gctatacaaa cttaggccgt gaacaaactt cttatactta
   112501 tctaggattc aagttaggta aatggaatgc agatacaaag agtgtggaat acaatccaga
   112561 ttcaaaaatg gctgataaat cattacgtca agcaatgggc tatgcattag ataataatgc
   112621 agtaggtgaa cgtttctatg caggtttgag aagcaatgcg acttcattga ttcctccagt
   112681 attccagtca taccatgatg atgagatgaa aggattcaca caagatctag acaaagcgaa
   112741 aaaactatta gatgatgctg gctacaaaga tgtggatgac gatggtttaa gagaagacaa
   112801 agatggaaat aaactaacaa tcaactttgc ttcgatgtcc ggtggggaaa cagcgcaacc
   112861 attggcagat tactatatcc aacaatggaa agaaattggt ttggatgtcc aatacacaac
   112921 aggtcgtctg atcgaattca attctttcta tgataaatta gaaaacgatg atcctgaaat
   112981 tgatgtttac caagctgctt ggaatacagg aactgatcca aatccaagtg gactatgggg
   113041 accaaatgct gcgttcaact acactcgtta tgaatcagaa gaaaatacaa aattgatcaa
   113101 cgatatcagt tcaagcaaag catttgatga agagtaccaa aaagaagcat atcaaaaatg
   113161 gcaacaatat gcatttgaag aagcatttgc gattccaacg ttgttccgta atgaagtatt
   113221 gccagtcaac gaccgtgtca aagactggga ttggtcttat gatgtaccaa acccatgggc
   113281 aaatgtttct gttacagcag attcacgttc ataatcacta aaaatgaccg aaaaagggcg
   113341 atgtcctttt tcggtttttt gatatttttc tgtttatttc tctaatattc aggtcaaggc
   113401 gctgatttca tgacttctcc aataaacggt gttcaaagtc cagtttctcg gtattaagtc
   113461 aaatttatgc aaaaatatgg aaagccattt tcacaaaatt ttttcttcat actcgaaact
   113521 aaacgaattt ttcacaactt ctcgtcaatc actaggatta ttaaagcttt acttaccttt
   113581 tgaccgaacc atttcaaatt tgacaaaaaa ccagtataat aaggaagtat cgaaaaaata
   113641 tccataaaag gaatgtggaa aatggacaac cagctgacaa aagaactaaa agaaaactat
   113701 aacatcgttt ttcacgatct aaatttgctt gaacaagctt ttacccattc atcctatgtg
   113761 aatgagcatc gcaatctgca attatcggat aatgagcgac ttgaattttt aggagatgcc
   113821 gttttagaac tgatggtttc tcagtattta ttccgtttat atcctcattt gccagaagga
   113881 aaattgacaa aaacacgagc tgcgatcgtt cgcgaagaca gcttgtcgaa atttgccaaa
   113941 gaatgtcact ttgatcaata tgttttgttg ggcaagggag aagagaattc aggaggacgt
   114001 acgcgaccag cattgctttg cgacctattc gaagcttttt taggcgcgtt atatcttgac
   114061 cagggattcg acacgaccca tgcattcatc gaaaaagtga tttttcctaa agtcaaagca
   114121 ggtgcttttt cacatgagat ggatcataaa acaaaactac aagaagtctt gcaaaaatca
   114181 ggtgatgtat caatcgaata ccgattgatc aatgaagaag gtccagctca tgaacgagta
   114241 ttttggatcg aagtttatgt agatgatcaa ttgattggca ctggacaagg gaaatcgaaa
   114301 aaattagcag aacaagctgc ggcggaaaat gcattggcag cactgtaaaa gtaagtgagg
   114361 gaaagctttg tatttgaaac gaattgaaat agccggtttt aaatcatttg cagacaagac
   114421 agtcattgat tttgaaaata gcgtcacagc agtggttgga ccaaatggca gcggaaaaag
   114481 caatattaca gaggctatcc gctgggtatt aggagaacaa tctgctaaaa gtctgcgagg
   114541 cggaaaaatg ccggatatca tctttgccgg ttccgatacc cgtaagcagc tgaatattgc
   114601 agaagtcaca gtgattttag acaatagtga tcattatctg ccattggagt acaatgagat
   114661 cagtgtaacc cgccgttatc gacggactgg ggaaagcgag tttttcatca ataaacaaag
   114721 ctgcagatta aaagatatcc aagaattgtt cttagattct ggattaggaa aagaatcgtt
   114781 ctcaatcatt tctcaaggaa aagtagaagc gattttcagt agtaaaccgg aagaccgtcg
   114841 tgggatcttt gaagaagcag ctggtgtctt gaaatacaag cagcggaaaa agaaagcaga
   114901 acagaagctt tttgaaacag aagacaacct cagccgcgtc caagacatca tccacgaatt
   114961 ggaagaacag ttaactcctt tggccgccca gagtgaggca gcaaaggagt ttttacggct
   115021 aaaagaaaca ctgactcaaa ccgatgtctc tttgatggtt gctgaaatca agacagcaaa
   115081 aaaagattgg gacaacaaac aagcacagct tgcgaaattc aatctagaat taggcaaact
   115141 atctgagtcg atccaagaac aagaatccat tttggcgaag cagcgtaaag aaaatgcgca
   115201 agccgatcgt ctgatcgaaa aaaatcagca agtattatta gatctttcgg aaaaactgaa
   115261 gcagacagaa ggacaaaaag atgttttgca ggagcggaca aagcatacac aaaaaagctc
   115321 gcaagaatat caaacttcat tagcagaagc acaaaaaaag gttaaacatt ttgaaaagct
   115381 tcaagaaagc ttgatgaaag cagcagcaga aaaagaaaca gagatccaaa aagctgaagc
   115441 aaatctcata aaaacacagc aagaattaga aaaataccaa aaatcaacga aagaattatt
   115501 ggcagaatta agagatcaat atgttgattt gatgcaagaa caagcagctg taggaaacga
   115561 actgaagtat ctagaacgtc aatatataca agaaacagca aaaagcaagc agacgttagc
   115621 caagcaatcg gaagtagaag catcagtaga ccgattgatc ttacaaaaag aagaattgac
   115681 acaaaagcag gcgcagctaa aatcatcttt aactgaaaca aaagagaagt tagaaatgat
   115741 ccaacaaaac gggaaaaagt tccaagaagc attagcaaaa gaacagccta aaatgtatca
   115801 attaatgaat caagtccagc agctacgtgc tcgtaagaaa agccttcaag aaatccaaga
   115861 aaactatttt ggtttttacc aaggggttcg attggtcttg cagcataaac agcagctttc
   115921 gggtattgtc ggagcagtgg ctgaactgat cgatgttcct gcagatttca cgttagctat
   115981 cgaagcagct ttaggtgggg cagcccagca tgtcatcgtt gaaaatgaaa aagatgctcg
   116041 gcaagccatc acgtatttga aacagcaaag aggaggaaga gcaacattcc ttccactgac
   116101 gacaatcaaa ccaagacaat taccggctca tatattgaca caagcagcag ctgtagaagg
   116161 gtttataggg attgccagtg aacaagtcag ttatcccgat caaatccaaa ctgtggttca
   116221 aaacctgcta ggaacgatcc ttttagccaa agacttaact agtgccaatg caatcgcgca
   116281 aacgatccgc tatcaatatc gagtggtttc cttagaaggt gatgtgatga atgccggagg
   116341 atccatgaca ggtggagcga ataaacgagg aaaccaaggc agtttgtttg tacaaaatca
   116401 agaattgaaa cagttgacta gtgaatttga agaagcagat aaacaactcc aagcacaaga
   116461 aaaaaaagtt caggagctgc aacaagaaac agctcgttta gccgaagaac aagaagtttt
   116521 gcgtacacga ggcgaacaat tacgttttga agaacaagaa gcgacaaatc agctacaaaa
   116581 catcataaat gaacttgaac gttttgaaaa agaaaagcaa atctcaactt ttgagacacg
   116641 tgaactgcag cagtttatcg aagattacga aaagcaaacg aacgaattga aagacaaaca
   116701 aacagatctt gaatcgcaac gacaaaaaat cgacgaagaa atcaaatcgt taagtcaaga
   116761 aagcgaccag atggaagcca gaagagcaca agtacaaagt caaaaagcac aagaacaagc
   116821 agatcttgct gtcttgaaag agcagtttaa tcatctgcag atccagctcc gcggtgcccg
   116881 agtccaaaaa gcagaggcaa ccgaacgtca agaagcgata gaaaagcagt tggcgacatt
   116941 gacagcagac ttttctgatc atgaagtcac agaagaaagt ttggaaaaac aaattaacga
   117001 attatctgct cagcgagaaa cattaaaagc cgagttggca aaagccaaag agcagcgaga
   117061 tagaaggcaa aaggagatcg ataagcttga agcagtcttg gcagagcgta atcgtgagca
   117121 aaaagcacga ctgtcggaac aatccaaatt agaagtccaa aaagaccgag ctgaaatgat
   117181 tttagataat catttgacct atctgcagtc agaatatcag ctgacatttg agaaagcttc
   117241 ccaagactat caagaaacaa ccgatatcga agacagtaga acaaaggttt catccttaaa
   117301 agaacagatt gaaaaactgg gaccagtaaa cttaaattca atcgaacaat acgaacaagt
   117361 cagtgaaaga catacattct tagcaacaca gcgagatgat ctgttagcag cgaaaaacca
   117421 attgtttgaa acgatggatg agatggatga tgaagtgcgg acaagattca aagaagtatt
   117481 tgaagctatc cgtcaagaat tcaaaattgt ctttccaaat atgtttggcg gcggtaaagc
   117541 tgaattagta ctgacggaac caactgattt gctgaaaaca ggtattgaga ttgaagtaca
   117601 acctcctggc aaaaaactgc aaagtctaag tttgctttct ggaggagaac gagcacttac
   117661 agccatcgcg ttgctctttt ccattatccg tgtctgtcct gttccgtttt gtatcttaga
   117721 tgaggtagaa gcagcgttag atgaagccaa cgtgaaacgt tttggtcgtt acttgagcga
   117781 tttccaagat gacacacaat ttatcgtagt cacacaccgc aaaggaacga tggtcgcagc
   117841 agatgtactg tacggagtga cgatgcagga atccggtgta tcaaaaatcg tttctgtacg
   117901 gatggaagat atcaatgaag aggcgaaaat caacgaaacg aaagtgtagg aacgaaaatg
   117961 atcaaattag tagcaatcga tttggacggt acattattaa atgaacaaaa gctgatttca
   118021 gatgagaata aacaagcatt agcacaagca aaacagcaag gggtcaagat cgttctatgt
   118081 acaggacgcc ccttagctgc gatggcgcat tatctgcaag aattaggact ggtagatgaa
   118141 ggtgactaca gcatcacttt caacggcggt ttggtacaaa aaaatgatac tggtgaaatc
   118201 atggaaaaga aagtgatgga agtatcagat atccaacgct tatacaaact ggctcagcaa
   118261 ttggatctgc cactagatgt tttgtctgac aatgtggttt tacagctgcc tagtgcccca
   118321 aggaagcaat ccttgtacaa tgtgttgaat aagctgctgc aattccaacc agcggatata
   118381 agcgatatta cagatgaatt tgtgcttaat aaggcagtaa tcgcttatga ccaagaagaa
   118441 ttagatccta aaatcaaaga aataccagca gaattccatg aaatgtatga gatcatcaaa
   118501 acaagaagta tgcttttgga atttatgcca aaaggtgtta caaaagctta tggtatttct
   118561 ttattggcaa aagatcttgg tttgaaacaa gaagaaatca tggcgatcgg tgatgaggaa
   118621 aatgatttac cgatgatcca atatgctgga ctaggcgtag cgatggagaa tgctgtgcct
   118681 ttcgtcaaag aagcagcaga tttcgtgaca gccagcaatg aagaaaatgg cgtagccaaa
   118741 gtgatccaaa aatttgtatt agagtagggg gagtcaaatg ggattttttg ataaaatcaa
   118801 gcgtgctttt actggcgaag agaaaacaga agaagttgaa gtacaggaga agtacgacaa
   118861 gggtttagaa aagacgcgta aaacatttgg tgaacggatg aatgagttgt ttgccaattt
   118921 tcgaacagtc gatgaagact tttttgaaga attagaagaa acacttatcg gtgcagatgt
   118981 aggttttgaa acagcgatac gaatcaccga agcattacgt caagaagtga aactcagaaa
   119041 tgcgaaaaaa tcggcagaag tccaaaatgc gatcatcgag aaacttgtgg atctctatga
   119101 agcggaagga atcaatgaag taaatgaact aaatatccaa gaagacggac taacagttat
   119161 tttgtttgtc ggtgttaatg gtgtagggaa aacaacaagt attggtaaac ttgcccatca
   119221 gttcaaaaac gaaggtaaaa aagtattgat ggcagcagca gataccttcc gcgctggagc
   119281 aatcgaccag ttagttgtct ggggcgaacg cgctggtgtt gaagttgttc gtggcaatgc
   119341 aggaggcgat ccagcagctg tcgtattcga tgctttggaa agagcaaaga cagagcaggc
   119401 agatgtttta ctagttgata ctgcaggccg actgcaaaat aaagtgaact tgatgaacga
   119461 attagaaaaa ataaaacgag taatccagcg ggaattacca gaagcacccc aagaaacact
   119521 tcttgtatta gatgcaacca ctggtcaaaa cgcgatggtt caagcaaaac aattcaaaga
   119581 aacaacagat gtgaccggtc ttgttttgac aaaattagat ggtacagcaa agggcggtat
   119641 cgtacttgct atccgtaatg aattgcattt accagtgaaa ttggtcggtc ttggtgaagg
   119701 aatcgatgac ttggagccgt ttgatccaaa tgattttgtc gttggattgt tcaaaggatt
   119761 actaaaagaa gaataaccca tgtctaaaaa gcaggagctg tgacaaaagt tgcagctcct
   119821 tgtttgaatg attgttttta acatagctgt gtttttgatg ccttcatttt tatacttatt
   119881 tgtaagcggt tctcaaacaa tttcgttctt tttcttagac tttttgatta taattagatt
   119941 catatgaatt ggaggtcact taatgatgaa ttttaagcaa ttattattgc atgtcaatgc
   120001 gcgccctttt atcgaccaag ctcgatttgg tatagaacgg gaaggacagc gggttgatct
   120061 tgcaggaaat ctagcaaaaa ccgatcatcc agcaatcttt ggcgatcgat cctatcaccc
   120121 ctatatccaa acagatttta gcgaaacaca aacagagatg atcacccctg ttaccgattc
   120181 tattcccgaa ttatttcagt atctcgctgc tgtttatgat gtgactgctc gttctatacc
   120241 gaaagaagag atgatctggc cattaagtat gccacctgcc ttaccggaaa aagacgaaga
   120301 gatcattatt gcaaaattaa aaaatttcga agatgtcttg tatcgacgtt atttagcaaa
   120361 agaatacggg aagcgaaaac agatggtaag cggtattcat ttcaattttg aatttggcga
   120421 tgagttgcta agaacattgt tcagccatca ggaagaattt caagattttt ccgaattcaa
   120481 aacagaactt tatttgaaaa cagcgagaaa ctttatgcgc tatcgctgga tgatcactta
   120541 tttattcggt gcttcaccaa tgagtgagaa gaactacttt ttagatgaat cacatccgca
   120601 agaacctgtt cgcagtattc gcaacagtgc gctgggctat acgaatcatc caaatgtgaa
   120661 agtttcctat gcttctatga aacagtattt agcagatatc gagcgaatga tcgaagaagg
   120721 gaaactttcg gaggagaaag aattttatac accgcttcgt ttccgaggcg gaaagaaagt
   120781 cgcagattta gcaacaacag gtgttcgtta tattgaattg cggaatatcg atttgaatcc
   120841 ttatgcaaga ttgggtatca atccagagca agttcggttc ttacaattat tcctgatgta
   120901 catgttatgg acagaagaaa aagaagactg tgaccaatgg gtagcagaag gtacgactcg
   120961 aaataacaaa gtagcactag aacaaccatc agatcaaaca gaatttcatc aagaaggtag
   121021 agaaattctt gaaggaatga agcaaatgct ggttgaattg gattggttgg attctcttta
   121081 tttagtagag gaagcattga ctcaaatgga tcatcctgaa caaacgttag cagcgaaact
   121141 ctatcaagaa gcacagctat cgagtcagca agaagttgct gtggcattgg gacatcaata
   121201 ttataaagaa agccatgaac gtccctatca gttggccggt tttcgcgaaa tggaactttc
   121261 tactcagata tttatgttcg atgccatcca aaaaggtgtc caagtcaaag tattagatga
   121321 gtcggatcaa tttttgcgtc tgcaattcca agaccatgta gaatatgtga aaaatgcaaa
   121381 catgacaagt aaggacagct atatcgtccc acttatcatg gaaaacaaaa cagtaacgaa
   121441 aaaagtctta aaagaagctg ggttccgggt accaggaggc gcagaatttt catccatgga
   121501 agaagcggta aaagcttatc cgagatttgc cgagcaggca tttgtgatca aacctaaatc
   121561 aaccaattac gggttaggta tcacgatttt caaggaagga gctagtctgg aagattatca
   121621 agcaggttta gccattgctt ttcgtgaaga cagttcggtt ttagtagaag aatttatgcc
   121681 gggaacggaa tatcgtttct ttgtgatcga cggagaagtc caagccatca tgttgcgagt
   121741 ccctgctaat gttattggtg acagtatccg aacagtgaaa gaacttgttg aagaaaaaaa
   121801 tagtgaccct ttgcgtggaa cgaatcatcg tgcaccttta gaattgatcc aattaggtga
   121861 attagaacaa ttgatgttga aagaacaagg gttgacgatc gaatcagttc cccaagccaa
   121921 tcaaattgtt tatctaaggg agaactcaaa tatcagtaca ggtggtgatt cgatcgatat
   121981 gactgatgaa ttttctgaag cttacaaaaa aatcgccgtt tctgcggtag aagcactagg
   122041 agctaagatt agtggtatcg atttgattat accagataaa gaaatcgatc ctacaactga
   122101 taaaaaagca tatgggatca tcgaagcaaa tttcaatcca gccatgcata tgcatgttta
   122161 tccttttgca ggaaaaggca gaagattgac gatgaatgta ttgaaattgt tatatcctga
   122221 agtattttaa aagaaaaagc ttttgacaga ttgtcctatt tgatgtcaat ctgatcaaaa
   122281 gctttttttg catg
//
LOCUS       DAPBAF010000002       106086 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.002, whole genome shotgun sequence.
ACCESSION   DAPBAF010000002 DAPBAF010000000
VERSION     DAPBAF010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 106086)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 106086)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..106086
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.002"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(564..1049)
                     /locus_tag="RD451_000123"
     CDS             complement(564..1049)
                     /locus_tag="RD451_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIR domain-containing protein"
                     /protein_id="HDT7565422.1"
                     /translation="MVRRVFFSFHYADVTRAMVVRNSWTLRGTKEAGFVDKAEFEKVK
                     RNGDIAIKNWIDNQLIGTSVTVVLIGKETLDREYVKYEIQESYKRGNAILAVNIGKIK
                     DFNQMTTTSQSVIKIIGQKPDGEYLWFDEIIDGQYDYISDDGYNNLGTWIDSAAYKKG
                     K"
     gene            complement(1051..2487)
                     /locus_tag="RD451_000124"
     CDS             complement(1051..2487)
                     /locus_tag="RD451_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HDT7565423.1"
                     /translation="MDKKVLIKRFSEAIEKGNAAIFAGAGLSMSQGYVSWPELLNDPA
                     TEIGLDSKKETDLVTLAQYYKNENGGSRGILNQILMDNFGEELEISENHRILASLPIE
                     TYWTTNYDHLIEKSIREAYKNPQVKKNYTQLATTNPNVDTIVYKMHGDIDDVSSTVIT
                     RDDYEKYDDDSYALFKETLKGDLLTKTFLFLGFSFTDPNLERILSDIRWVLRENQRPH
                     YCIMRKILKENFVDSEDFFDQERYNYELTKRRLQINDLSRFSINVVEVDDYSEITDIL
                     KSIRKKYLRKTIFISGSAVDYTPFTSESKGLKFVEKLAYRLSESGYRIVSGYGLGIGN
                     SIVSGVLKQRRNLRKNNIQDVLSLRPLPLDMPHEWRRYRENIIAESGISIFVFGNKLE
                     SGEIVTADGMIEEFELSVQNENIVVPIGFTKGASKVLFDKIQENFSDYFDDSLKSKFQ
                     ALEKLDTEGEVDKKVEQIVSLINSIQED"
     gene            complement(2520..3371)
                     /locus_tag="RD451_000125"
     CDS             complement(2520..3371)
                     /locus_tag="RD451_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toll/interleukin-1 receptor domain-containing
                     protein"
                     /protein_id="HDT7565424.1"
                     /translation="MYKAYELDFTNADLNAFSSSSQSYTHVVNQIDHNQKSINKRIEN
                     LFESENDLVDYYSKDSKILDADEIIKDWFPTIKADIFISHSHADEKLAIRFASWLFEN
                     FGLTAFIDSSVWGYSSDLLKKIDQKYCYKEQTKTYDYDKRNVTTSHVHMMLSTALNNM
                     IDSTECLFFLNTPNSISLSNEITNEQKFTYSPWLYSELTTASIVEKKNPRLESNPQMS
                     TEDVRSIIKHYSSQENLQIKYSLNLSELTYLRKADLKKWALDAVECTKGSNTLDILYK
                     NTIFTNL"
     gene            complement(3527..3772)
                     /locus_tag="RD451_000126"
     CDS             complement(3527..3772)
                     /locus_tag="RD451_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7565425.1"
                     /translation="MLFLKEEKIIDKENVIGSNIRRVRLEKGIGQTELIRDLQLRKIA
                     ITRETLVKIEGGRQHIKLDQLKAIKDILQVSYEDLLQ"
     gene            3877..4650
                     /locus_tag="RD451_000127"
     CDS             3877..4650
                     /locus_tag="RD451_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565426.1"
                     /translation="MKKFAIILTCALLIGTISGCTTSDTSSTSTETSTTTSEKNYPIH
                     FFPVPDGFEAYYHDKKLDVPLSETESTEKILPIEIERNQDDIKLKADLPLLNSTQIDR
                     HENIKVNIEKGALAQLYTEKVEQFFEAGANKDFSKISDYSDNFFNETQDEITNSTFMA
                     EDMYNMKLKKIKSYDYPLNLTLNKGILSFVLAGYVDYEYTADYLETPLQHDNNDINFR
                     FIYNSKSKTWLVDQLSTINTGFHELPKPDNETALVIKTF"
     gene            complement(4703..5017)
                     /locus_tag="RD451_000128"
     CDS             complement(4703..5017)
                     /locus_tag="RD451_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565427.1"
                     /translation="MADENKVVPLETLVINKEEFEQLFLDFFVQYDRIYDFSSSLDLF
                     ELEAEIIENSREENGKIIISVEKFNELFSETFEIDTDYYQPQEVFQSFRNQIIRSGKT
                     VN"
     gene            complement(6536..6754)
                     /locus_tag="RD451_000129"
     CDS             complement(6536..6754)
                     /locus_tag="RD451_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565428.1"
                     /translation="MKLILKISTHDFLELDELCESVKNATNEKITVTNYIELMIQEEL
                     KMKHEIKNNLKYCYLEKSEEIIHELNGF"
     gene            complement(6769..9396)
                     /locus_tag="RD451_000130"
     CDS             complement(6769..9396)
                     /locus_tag="RD451_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565429.1"
                     /translation="MKAIKEKIVSRKINWLALSVLVLMISVVFTSNIVEASIFNWFDD
                     TKSQTEFLNNSLYRPYLKKYNGDFLSQFGIWLGWAVVKGMFTVTDSIQNMIPDVLDLF
                     NFIESTGLNNVYQSVINTIVVGLMILSLMFVGYKMITGKGTIDLRSVGMNIVMSVALI
                     LLMPTMISSGIQFAKIFYNDATTITNSDDGVAWSLIKQGVTDLAYINKTDQYSSIDKT
                     EDRNKLTRKNFQQTDLTQVLTDKVIDKLEKENPAADNLRYELVENSNNEFVATKFSDN
                     FLSTFSDSLKSGYYRYQANLWGISIGLTALAIAYVFSAFVIITAILELAFKRVLGVLV
                     FATDIETGQRSKVVLSDILQCYLTVGFQGFGLSMFAMFINFLNAGQGISTNIFIKTIA
                     YICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGSTGFNRAKGSGN
                     GNGSDSGEGEDRKPEKNFGETLSKKAGKTGRALGYAHERGLSGLASDGATMASERAIK
                     PFKSMRDMANDTKNKFKEGLDDGTVSAINKNSKPMLAKNKEDETGKYADSMPTRLSDR
                     KDGAKVENADRIMSSSERMREAMKNNAESNNNPVSAIQQKVQQDIEERKNAMHGQAKS
                     AEELINQKRQEAKYTPEAMNREEMLRKRVEGRTGANTDEKEALTKERIQEAKNSNTGL
                     EKLVKENLQNSTSSQGGRSVDVRENIQGSLNGHVGRNVDVRENLQSSSNGQGTKTIDV
                     RENVQNSTSSQGFKSMDVRENVQNSTSSQGFKSMDVRENVQSSTSSQGFKTVDVRENV
                     QKDSGEMKEKTQKINIVEDRKSAKKFDSNHETVIIDSEIRENDKGSKPRRRFTYEDNE
                     LFRDTLNDPNPLFDNLLKK"
     gene            complement(9383..9601)
                     /locus_tag="RD451_000131"
     CDS             complement(9383..9601)
                     /locus_tag="RD451_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565430.1"
                     /translation="MIKNRLIDQMWCLDQNTDTLELIESICFNTVVLDLRAENDNCVT
                     HIIINQKMAQQLSESLRKWAEGENYESN"
     gene            complement(9598..10473)
                     /locus_tag="RD451_000132"
     CDS             complement(9598..10473)
                     /locus_tag="RD451_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565431.1"
                     /translation="MNAIVILAEITYWYRPKKIFNDDGQLLGYQKKFLEDILQKSYKQ
                     LSKKTGLSERAIKDAIVYLEKKGIIKRVFRNIYYEKRAVTLSNVMYIVLNVHKLIEIT
                     FPTLDCEKKEYMPKIRQRGIEKKRYVSLKKGRGMYKFVYTYTKTTSQNISKTTLVMEE
                     EDINIKRIYSKISVLYDANNEDGRKLFQVYHYLRNANVDTEDIRKIIEYLSENTQYLI
                     AECIIKQHEACFFQRKTEEGLYDYVTYFLNGLQKRYKSQFLENVEPIDQFKKAFEIKE
                     LPEITMHNWLKGEES"
     gene            complement(10738..11037)
                     /locus_tag="RD451_000133"
     CDS             complement(10738..11037)
                     /locus_tag="RD451_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7565432.1"
                     /translation="MEAIKLMISEEQEEMFLKQFYQIATKAIEKAQENAGMTREYLNQ
                     KEMAEYLNVSENFLKNAVRNEGLPVVELGARKFYSKKAVNEFMFARMKRGENIGR"
     gene            11239..12036
                     /locus_tag="RD451_000134"
     CDS             11239..12036
                     /locus_tag="RD451_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7565433.1"
                     /translation="MKPNPSEAGKRIKQLRLSCGFTMEELGRKIDNSPRATISNWERG
                     TNLPNPQKLKLLSTITNSTIDWIKWGTLEEYITSYLIDIGYELYIKDFPEIPHKVFKD
                     IQERYSDTFSLDKDYELLNPIIKNIFTKYYSKDFEIYLNEILANNINPLIEEYANQRH
                     SISKELFFKRANSKLQDKIRNGDFKYGEKERMIDSLKQLLDEMDLAYKDISKYSSVED
                     FFYKITKNQFETEKFISDLSKKYNFPYEKNSIIAKFLTDNHDKFKNN"
     gene            12087..13229
                     /locus_tag="RD451_000135"
     CDS             12087..13229
                     /locus_tag="RD451_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDT7565434.1"
                     /translation="MATFFSYKLQNGEKYWGFETYLGKDPKTGKDIRTKRRRFKSKAE
                     AQTALNRLLVDFKEKQEFKINVTTFQELYELWIDNYRTRVKPSSVAVAQRFCKNHILP
                     AFGELRLDKISVSYCQKQVNEWHKTLKQYGFLRKTTAQIFKFGVAMEVCKDNPMSKTL
                     LPRKIEEEQPLKFYTKDQLQLFLQNTKENNSVKLYTFFRLLAYTGMRKSEALALQWED
                     IDYFNKTITIGKTIAQDEFNQVVLQVPKTKNSSRTIQLDDFTLKQLRIWQQEQMKIMI
                     LYGYNTNSPKQFLFTTNTNKLYYPQVVNDWLDWIYKKTPMEPQITPHGFRHTHCSLLF
                     ESGASIKEVQERLGHKDIKTTMNIYAHVTPQSVKKTGDRFAKFMGE"
     gene            complement(13327..14718)
                     /gene="sufB"
                     /locus_tag="RD451_000136"
     CDS             complement(13327..14718)
                     /gene="sufB"
                     /locus_tag="RD451_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HDT7565435.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(14723..15193)
                     /locus_tag="RD451_000137"
     CDS             complement(14723..15193)
                     /locus_tag="RD451_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HDT7565436.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            complement(15180..16415)
                     /locus_tag="RD451_000138"
     CDS             complement(15180..16415)
                     /locus_tag="RD451_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HDT7565437.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            complement(16412..17698)
                     /gene="sufD"
                     /locus_tag="RD451_000139"
     CDS             complement(16412..17698)
                     /gene="sufD"
                     /locus_tag="RD451_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HDT7565438.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            complement(17711..18484)
                     /gene="sufC"
                     /locus_tag="RD451_000140"
     CDS             complement(17711..18484)
                     /gene="sufC"
                     /locus_tag="RD451_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HDT7565439.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            complement(18681..19529)
                     /locus_tag="RD451_000141"
     CDS             complement(18681..19529)
                     /locus_tag="RD451_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HDT7565440.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            complement(19553..20239)
                     /locus_tag="RD451_000142"
     CDS             complement(19553..20239)
                     /locus_tag="RD451_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7565441.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            complement(20232..21266)
                     /locus_tag="RD451_000143"
     CDS             complement(20232..21266)
                     /locus_tag="RD451_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDT7565442.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     misc_binding    complement(21329..21585)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(21661..21999)
                     /locus_tag="RD451_000144"
     CDS             complement(21661..21999)
                     /locus_tag="RD451_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HDT7565443.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     gene            complement(22001..22357)
                     /locus_tag="RD451_000145"
     CDS             complement(22001..22357)
                     /locus_tag="RD451_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HDT7565444.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            complement(22363..23550)
                     /locus_tag="RD451_000146"
     CDS             complement(22363..23550)
                     /locus_tag="RD451_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HDT7565445.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            complement(23741..24586)
                     /locus_tag="RD451_000147"
     CDS             complement(23741..24586)
                     /locus_tag="RD451_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDT7565446.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            24820..25785
                     /locus_tag="RD451_000148"
     CDS             24820..25785
                     /locus_tag="RD451_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HDT7565447.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            26162..27205
                     /locus_tag="RD451_000149"
     CDS             26162..27205
                     /locus_tag="RD451_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HDT7565448.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(27267..27731)
                     /locus_tag="RD451_000150"
     CDS             complement(27267..27731)
                     /locus_tag="RD451_000150"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HDT7565449.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            27977..28924
                     /locus_tag="RD451_000151"
     CDS             27977..28924
                     /locus_tag="RD451_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDT7565450.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            complement(29135..31207)
                     /locus_tag="RD451_000152"
     CDS             complement(29135..31207)
                     /locus_tag="RD451_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HDT7565451.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(31140..31517)
                     /locus_tag="RD451_000153"
     CDS             complement(31140..31517)
                     /locus_tag="RD451_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HDT7565452.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            complement(31646..32224)
                     /locus_tag="RD451_000154"
     CDS             complement(31646..32224)
                     /locus_tag="RD451_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDT7565453.1"
                     /translation="MRGNMEMKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDI
                     KAPSLYNHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSN
                     QAVYELLISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYL
                     SLRFLGYFTKEPTIDPEDSYFWMINNFIATLP"
     gene            32356..33648
                     /locus_tag="RD451_000155"
     CDS             32356..33648
                     /locus_tag="RD451_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HDT7565454.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSIASGHSPSHRQ"
     gene            complement(33708..34826)
                     /locus_tag="RD451_000156"
     CDS             complement(33708..34826)
                     /locus_tag="RD451_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HDT7565455.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(34840..36261)
                     /gene="arcD"
                     /locus_tag="RD451_000157"
     CDS             complement(34840..36261)
                     /gene="arcD"
                     /locus_tag="RD451_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HDT7565456.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            complement(36507..37628)
                     /gene="mnmA"
                     /locus_tag="RD451_000158"
     CDS             complement(36507..37628)
                     /gene="mnmA"
                     /locus_tag="RD451_000158"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HDT7565457.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            38032..38631
                     /locus_tag="RD451_000159"
     CDS             38032..38631
                     /locus_tag="RD451_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HDT7565458.1"
                     /translation="MNYFISDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            complement(38769..40055)
                     /gene="efmA"
                     /locus_tag="RD451_000160"
     CDS             complement(38769..40055)
                     /gene="efmA"
                     /locus_tag="RD451_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HDT7565459.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(40326..40670)
                     /locus_tag="RD451_000161"
     CDS             complement(40326..40670)
                     /locus_tag="RD451_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HDT7565460.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            complement(40807..41952)
                     /locus_tag="RD451_000162"
     CDS             complement(40807..41952)
                     /locus_tag="RD451_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HDT7565461.1"
                     /translation="MNEVKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGR
                     HAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIE
                     HPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLM
                     PIKEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKR
                     DGVNIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLIL
                     DTLEANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNI
                     EPSHVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            complement(42132..43106)
                     /locus_tag="RD451_000163"
     CDS             complement(42132..43106)
                     /locus_tag="RD451_000163"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HDT7565462.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            complement(43186..44061)
                     /locus_tag="RD451_000164"
     CDS             complement(43186..44061)
                     /locus_tag="RD451_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HDT7565463.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            44191..46098
                     /locus_tag="RD451_000165"
     CDS             44191..46098
                     /locus_tag="RD451_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M13 family peptidase"
                     /protein_id="HDT7565464.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            complement(46639..49917)
                     /locus_tag="RD451_000166"
     CDS             complement(46639..49917)
                     /locus_tag="RD451_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1565 domain-containing protein"
                     /protein_id="HDT7565465.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEIPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
     gene            complement(50188..50733)
                     /locus_tag="RD451_000167"
     CDS             complement(50188..50733)
                     /locus_tag="RD451_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HDT7565466.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDSVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(50745..51437)
                     /locus_tag="RD451_000168"
     CDS             complement(50745..51437)
                     /locus_tag="RD451_000168"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HDT7565467.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(51456..51740)
                     /locus_tag="RD451_000169"
     CDS             complement(51456..51740)
                     /locus_tag="RD451_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565468.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(51753..52316)
                     /locus_tag="RD451_000170"
     CDS             complement(51753..52316)
                     /locus_tag="RD451_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HDT7565469.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            52544..53206
                     /locus_tag="RD451_000171"
     CDS             52544..53206
                     /locus_tag="RD451_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HDT7565470.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            53330..54526
                     /locus_tag="RD451_000172"
     CDS             53330..54526
                     /locus_tag="RD451_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HDT7565471.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(54627..56003)
                     /locus_tag="RD451_000173"
     CDS             complement(54627..56003)
                     /locus_tag="RD451_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDT7565472.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(56040..56906)
                     /locus_tag="RD451_000174"
     CDS             complement(56040..56906)
                     /locus_tag="RD451_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose transporter GlcU"
                     /protein_id="HDT7565473.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(56995..58020)
                     /locus_tag="RD451_000175"
     CDS             complement(56995..58020)
                     /locus_tag="RD451_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDT7565474.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(58038..58712)
                     /locus_tag="RD451_000176"
     CDS             complement(58038..58712)
                     /locus_tag="RD451_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7565475.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(58896..59789)
                     /locus_tag="RD451_000177"
     CDS             complement(58896..59789)
                     /locus_tag="RD451_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HDT7565476.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(59863..61560)
                     /locus_tag="RD451_000178"
     CDS             complement(59863..61560)
                     /locus_tag="RD451_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HDT7565477.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(61553..62866)
                     /locus_tag="RD451_000179"
     CDS             complement(61553..62866)
                     /locus_tag="RD451_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HDT7565478.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(62866..66903)
                     /locus_tag="RD451_000180"
     CDS             complement(62866..66903)
                     /locus_tag="RD451_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HDT7565479.1"
                     /translation="MVVDERIDNQELQENETDTEDSAEIQRSEENEMEKLDEPIVPSG
                     QALQRIQRQLFNGILERLGPTATQDPYEYIYPSGEVENEQHRYPKFTTNDYTKVLGNW
                     TQSNERYQGDKGSPYDGENLIDDSDYTNGGANWRNYDYATNNGSTAGEEDRNVPAQTV
                     QLWGNERNFENSYLDYNGAYIKKWVEPVLPSSTASDLHPEDATTLYNVYLDVIGGEKK
                     EISPIDIVFVLDKSASMSELTAGTNSQTKNAALIEAVNEMSKDLLSDPSLDIRIGMVN
                     FYHNSTAINNHEQISSDIFPLTNDINRLTGSENTALNRTPIGGTPLTLGLKNGYETLY
                     KDNGGENRNPEKILIVVGDGTPTFSYAPIQSSYRTSTNGAWSNWTVMEDKIAEDNDVL
                     FRNFEEFSGNTSNAGFTHPVTYASDFNRPEDEVNVHYRYGEVKEGDNKATHWVGDGSS
                     NNNTNGSPTSQEKSSAINTVAYHHWLKNKYQENPPSIFSIGLGIDGNVSGRQRLDAIG
                     RNVLKNIADLEEDGVTPRYYNANNKNDIVTALEDISSTFKRTIQQATLYDETGFNVSP
                     FGAGRSADIQFYHLDPGENGMKYQEPEIWDEERHGQAPPEVVATPTTYVGRENQAYKF
                     SPISLGEGEMVRIKYQVKLDAGAQDGNFCTVNNMAYIQNLEDYENDITTGRMYFPSSS
                     IRYEHKGRNFQVSKKGQNGEPLAGVEFALYDQNPESGEAEPIETSKTTTDGIAIFETK
                     MPILGDETGAVSDIFWIREIAGPPRYQLVDETYQFQIKKYAANEDEMLGHYELVDEYT
                     SGSRVGGPEGKDPNSYYEGEYHKLSVVQEPNIEGTEYDELYVKLEMRNEFKPIHMNIN
                     KLIEGSNMPINGAEFELYETDGNGLEIGYPVAKGLSGVNEVEEEKGRLTFYSVDEDGK
                     YVIVDGEKVIHPIGEPDSFVYKDSEETTNYAEYKIIESQNPEGFKEPDENDTWILRLY
                     DNAIGTIQLKQTGEENWQYLTYTTDEEDRLWVAFTAYNTFDYREIRVRKLDHEGHTLD
                     GAGFDIRKVGDSSFPLYRAYTGNPLEPEESKRLPGIGYFYSRAVGVEKYVDLNYDQPL
                     HLSIGEYEVSESVAPNGYRLSDQVFQFALNEEGKFIIEDTVIEDETAPLPEGYEIIDG
                     VLQVTLEDELAPIDLELLKIDSMNSRRLEGAEFSIEKQNSAGEYEIIEGGLAPDPNDS
                     SLFNASDLLEGVYRIKEVKSPDSYRKLPGYFILEISYREEPDIENDRVVPGKEAGTLK
                     VEISYYPNEEAETPDLQQELEYELLETNRIRLQLSVGNDPENPLPATGGSGRLFYILL
                     AAFFMALAGAAYGLFVRQSKKEGAR"
     gene            complement(66916..67374)
                     /locus_tag="RD451_000181"
     CDS             complement(66916..67374)
                     /locus_tag="RD451_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDT7565480.1"
                     /translation="MKGLKLKLLQLVTVSLLFGPYFQSVYHMTTLDVAAESTETKEDE
                     VFLDEDYAKIEGKYIEKEETLEWHLAFEKKESANEGRIRLAIDAAAAGIGTVKNVRGT
                     GLSSYDEDGEDLKVETIDGQEWYVGKVYSKEAETGTLIFETEKIPDVNEG"
     gene            complement(67672..68190)
                     /locus_tag="RD451_000182"
     CDS             complement(67672..68190)
                     /locus_tag="RD451_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HDT7565481.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            complement(68192..68809)
                     /locus_tag="RD451_000183"
     CDS             complement(68192..68809)
                     /locus_tag="RD451_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HDT7565482.1"
                     /translation="MMNRSIGKKANDYFLEIIEWIPRLIHLQLLWFLCVLPVFTLGTA
                     SRTVLYMIYHYKKNEEKKLGSLFWKKFRENFSLYGKQDSLASVYFLLLLIDYQIFRYW
                     GGGIGYTLMYTTLFLLLLSALLFSYKILLQLEQKEASWITAFFLFFNDFKSALFYLAG
                     TLILLVAFWFAGPIYFALLGFSFLFYFQVLLFIHRTQEKVLKKEE"
     gene            complement(68806..69669)
                     /locus_tag="RD451_000184"
     CDS             complement(68806..69669)
                     /locus_tag="RD451_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDT7565483.1"
                     /translation="MTANDGLFQKDQCESANKKILSYVLMTVIGIILIIPLLWMVFTS
                     LKPMEEIVRYPPTFFPEKIVWENYLDTIAAFPFWRYARNTLFITVLVVIGNVLSNSFI
                     AYGFAKLDFPGKKLMFALVLSTMMIPGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGN
                     AFNIFLMRQFYLSINNELIEAAEIDGANHLYIWSHLMLPLTKPALITIAINSFNAAWN
                     DFLGPLLYIQDQEKYTLQIGLQVFQNQATTQWNYLMAGATLVLIPTILLFFFAQRYFI
                     EGMDLTGGSKG"
     gene            complement(69656..70567)
                     /locus_tag="RD451_000185"
     CDS             complement(69656..70567)
                     /locus_tag="RD451_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDT7565484.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAMSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(70608..71942)
                     /locus_tag="RD451_000186"
     CDS             complement(70608..71942)
                     /locus_tag="RD451_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDT7565485.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKIFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            72150..72980
                     /locus_tag="RD451_000187"
     CDS             72150..72980
                     /locus_tag="RD451_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HDT7565486.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(73224..73542)
                     /locus_tag="RD451_000188"
                     /pseudo
     CDS             complement(73224..73542)
                     /locus_tag="RD451_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028215.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(73664..73858)
                     /locus_tag="RD451_000189"
     CDS             complement(73664..73858)
                     /locus_tag="RD451_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565487.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
     gene            complement(74363..74548)
                     /locus_tag="RD451_000190"
     CDS             complement(74363..74548)
                     /locus_tag="RD451_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565488.1"
                     /translation="MSKNSKGFLTILLAFIGYMLVGLLKSYSNELLNFSTFINDTLVP
                     SLFFIVFFAVGYFIIKI"
     gene            complement(75398..75739)
                     /locus_tag="RD451_000191"
     CDS             complement(75398..75739)
                     /locus_tag="RD451_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HDT7565489.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(75739..75969)
                     /locus_tag="RD451_000192"
     CDS             complement(75739..75969)
                     /locus_tag="RD451_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HDT7565490.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            76256..76594
                     /locus_tag="RD451_000193"
     CDS             76256..76594
                     /locus_tag="RD451_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565491.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(76799..77038)
                     /locus_tag="RD451_000194"
     CDS             complement(76799..77038)
                     /locus_tag="RD451_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HDT7565492.1"
                     /translation="MFSNKEKIVYIGGFYRSHQDEKMAESIIMTTEPNRTVAPIHDRM
                     PLVLTEEQIEPWVTDISFARKIITQQMPELVMEKV"
     gene            complement(77014..77361)
                     /locus_tag="RD451_000195"
     CDS             complement(77014..77361)
                     /locus_tag="RD451_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HDT7565493.1"
                     /translation="MCGRYFFDLESELLQNYYREAQTKQPKQAAELAAGEVFPSNLVV
                     TLRKEEENILTPEIMKWGFTGFKKGQLMINARAETVEEKKTFHQPFLQNRCVFPMSGM
                     KKKTNLCFQIRKK"
     gene            complement(78093..78674)
                     /locus_tag="RD451_000196"
     CDS             complement(78093..78674)
                     /locus_tag="RD451_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDT7565494.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(78857..79483)
                     /locus_tag="RD451_000197"
     CDS             complement(78857..79483)
                     /locus_tag="RD451_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HDT7565495.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(79505..80836)
                     /locus_tag="RD451_000198"
     CDS             complement(79505..80836)
                     /locus_tag="RD451_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HDT7565496.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(80991..81392)
                     /locus_tag="RD451_000199"
     CDS             complement(80991..81392)
                     /locus_tag="RD451_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HDT7565497.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(81478..81684)
                     /locus_tag="RD451_000200"
     CDS             complement(81478..81684)
                     /locus_tag="RD451_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565498.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(81779..83281)
                     /locus_tag="RD451_000201"
     CDS             complement(81779..83281)
                     /locus_tag="RD451_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HDT7565499.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(83299..83754)
                     /gene="argR"
                     /locus_tag="RD451_000202"
     CDS             complement(83299..83754)
                     /gene="argR"
                     /locus_tag="RD451_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HDT7565500.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(83852..84469)
                     /locus_tag="RD451_000203"
     CDS             complement(83852..84469)
                     /locus_tag="RD451_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HDT7565501.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            84690..86063
                     /locus_tag="RD451_000204"
     CDS             84690..86063
                     /locus_tag="RD451_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDT7565502.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLFLSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            86138..87250
                     /locus_tag="RD451_000205"
     CDS             86138..87250
                     /locus_tag="RD451_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HDT7565503.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(87322..88959)
                     /locus_tag="RD451_000206"
     CDS             complement(87322..88959)
                     /locus_tag="RD451_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HDT7565504.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAAVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(89127..89735)
                     /locus_tag="RD451_000207"
     CDS             complement(89127..89735)
                     /locus_tag="RD451_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HDT7565505.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
     gene            complement(90119..91270)
                     /gene="queG"
                     /locus_tag="RD451_000208"
     CDS             complement(90119..91270)
                     /gene="queG"
                     /locus_tag="RD451_000208"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HDT7565506.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
     gene            complement(91289..92041)
                     /locus_tag="RD451_000209"
     CDS             complement(91289..92041)
                     /locus_tag="RD451_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565507.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            complement(92182..93132)
                     /locus_tag="RD451_000210"
     CDS             complement(92182..93132)
                     /locus_tag="RD451_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HDT7565508.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            complement(93133..93972)
                     /locus_tag="RD451_000211"
     CDS             complement(93133..93972)
                     /locus_tag="RD451_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HDT7565509.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            complement(93969..94715)
                     /locus_tag="RD451_000212"
     CDS             complement(93969..94715)
                     /locus_tag="RD451_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HDT7565510.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQSVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            94953..96323
                     /locus_tag="RD451_000213"
     CDS             94953..96323
                     /locus_tag="RD451_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDT7565511.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            complement(96378..97274)
                     /locus_tag="RD451_000214"
     CDS             complement(96378..97274)
                     /locus_tag="RD451_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HDT7565512.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(97388..97558)
                     /locus_tag="RD451_000215"
     CDS             complement(97388..97558)
                     /locus_tag="RD451_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565513.1"
                     /translation="MTNDWLIQQLDELSEKSEYQDRALLYEIKKLMAEIDERTMQLQG
                     EIDGQSWNHLNW"
     gene            complement(97555..98232)
                     /locus_tag="RD451_000216"
     CDS             complement(97555..98232)
                     /locus_tag="RD451_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HDT7565514.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            complement(98323..99228)
                     /locus_tag="RD451_000217"
     CDS             complement(98323..99228)
                     /locus_tag="RD451_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDT7565515.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            99403..100857
                     /locus_tag="RD451_000218"
     CDS             99403..100857
                     /locus_tag="RD451_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDT7565516.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANAATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMEDELHDAVDPSH"
     gene            100873..101904
                     /locus_tag="RD451_000219"
     CDS             100873..101904
                     /locus_tag="RD451_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HDT7565517.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGRFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            101911..103098
                     /locus_tag="RD451_000220"
     CDS             101911..103098
                     /locus_tag="RD451_000220"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HDT7565518.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            103254..104636
                     /locus_tag="RD451_000221"
     CDS             103254..104636
                     /locus_tag="RD451_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HDT7565519.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TEFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            104763..104993
                     /locus_tag="RD451_000222"
     CDS             104763..104993
                     /locus_tag="RD451_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565520.1"
                     /translation="MTLQEIDSILTEAFLSRKAVIIQLNLKDEFGRLLDEVEGHFIGE
                     AYEDYFMIDHQPILWEDVRYIELKETKKWFVT"
     gene            complement(105193..105861)
                     /locus_tag="RD451_000223"
     CDS             complement(105193..105861)
                     /locus_tag="RD451_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HDT7565521.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
BASE COUNT        30492 a        21973 c        18453 g        35168 t
ORIGIN      
        1 atatcaaggg ttctagctcc tataacaggt ttacccaaca ctgccttcca atgactcttt
       61 tgggaatcag aggaaagaat caggctttat agagatattt catctaacaa attactttag
      121 actgacagta tatatcagca ggtactgtca tcgggaacgt agccaatatc gtatccaaaa
      181 cagcaggtag agaagctatt tgaggattca agttattcta tttcaaccat gaagttaagt
      241 tcattaaaaa taaagatagt tggtatttca ataatttttg tatagagtta atcactttat
      301 tgatgctaat tcatcttgat tggtattata atcgtattca agttgcgtgg cgtgcttttg
      361 ctagaaaata tataactgtt ctttataaag aaatataagg attaaacatt ttttatcata
      421 gagttttact tatctataga attatgtctg ttcctaattc agtttgatga attaactgat
      481 aaaaaaatat ctactattta aagatacagg gataagtaag taaaaaaata acatgtcatt
      541 agatagtaga cagttccaac tctttattta ccttttttgt atgctgcact gtcaatccaa
      601 gttcctaaat tgttgtatcc atcatcactt atataatcat attggccatc aataatttcg
      661 tcaaaccaca aatattctcc atctggtttt tgcccaatta ttttaattac tgattgacta
      721 gtagttgtca tctggttaaa atcttttatt ttacctatat taacggccaa aatagcattt
      781 cctcgcttat aactctcctg gatttcatat ttaacatatt ctcgatcaag agtttcttta
      841 cctatcagca ccacagtcac tgatgttcca attaattgat tatctatcca gttttttata
      901 gcaatatctc cattacgttt aactttctca aattcagcct tatctacaaa accagcttcc
      961 tttgttcctc gcaaagtcca gctgtttcta actaccattg ctcttgttac atctgcataa
     1021 tggaaactaa aaaaaaccct tctcaccata ttaatcctcc tgaatactat ttattaaact
     1081 gacaatttgt tcaacttttt tatctacttc tccttcagta tctaattttt ctagcgcttg
     1141 aaatttactt tttaaggaat catcaaaata atcactgaaa ttctcttgaa tcttatcaaa
     1201 caaaacctta cttgcacctt tggtaaatcc aatcggaact actatatttt cattttgaac
     1261 agataattca aattcttcaa tcattccatc tgctgtaact atttcacctg attcaagttt
     1321 gtttccaaaa acaaaaatac taatcccaga ctctgcaata atgttttctc gatatcttct
     1381 ccactcatga ggcatatcaa ggggaagtgg tcttaaagaa agtacgtctt gtatgttatt
     1441 ttttcttaaa tttcttctct gctttagaac tcctgaaaca atactattac caattccaag
     1501 tccgtaacct gatactattc tataaccgga ttcagaaagc ctatatgcta atttctcgac
     1561 aaattttaat cctttcgatt cagatgtaaa tggagtataa tcaacagcac ttcccgaaat
     1621 aaaaatagtt tttctcaaat acttttttct aatacttttc aaaatatcag taatctcaga
     1681 ataatcatct acttcaacaa cgtttatcga aaatctggac aaatcattga tttgtagtct
     1741 tctttttgtc agttcataat tatatctctc ttgatcaaaa aaatcctcag aatcgacaaa
     1801 attttccttt aatatttttc tcattataca ataatgaggt ctttggtttt ctctcaaaac
     1861 ccatcttata tctgataaaa ttctttctaa attagggtct gtaaaactaa atcctaaaaa
     1921 gagaaaagtt tttgttaaca aatctccttt taaagtttct ttaaataacg cgtacgaatc
     1981 atcatcatat ttttcataat catctcttgt tattactgtc gaactgacat catctatatc
     2041 accatgcatt ttataaacaa ttgtatccac atttggatta gttgttgcta actgagtata
     2101 atttttctta acctgagggt ttttataagc ttctcggatt gatttttcta ttagatgatc
     2161 ataattagtt gtccaataag tttcaatagg taaacttgct agtattcgat gattttcaga
     2221 tatttctaat tcttcaccaa aattatccat aagtatctga ttcaaaattc ctcttgatcc
     2281 accattttca tttttataat attgagccag agtaactaag tctgtttctt ttttagaatc
     2341 caacccgatt tctgttgcag gatcattaag tagttccggc caacttacat atccttgtga
     2401 catcgataat cctgcacctg caaatattgc tgcatttcct ttttcaatag cttcagagaa
     2461 cctctttatt aaaactttct tatccattct acccggttcc tttcgattca gtaaattgat
     2521 tagagattag tgaaaatggt gtttttatat aaaatatcta atgtattact tcctttagtg
     2581 cattccacag catctaaagc ccattttttc aaatcagctt ttcgtaaata agttaattca
     2641 cttaaattta aagaatattt tatttgcaga ttttcttgcg aagaatagtg ctttataatg
     2701 cttctaacat cctcggtgct catttgagga ttactttcca atcgtggatt ctttttttcc
     2761 actattgaag ctgtcgtcag ttcgctatat agccatggcg aatacgtaaa tttctgttca
     2821 ttagtgattt cattgctcaa actaattgaa ttaggtgtat taagaaaaaa cagacattct
     2881 gtactatcaa tcatattatt taaagctgta gaaagcatca tatgaacatg actagttgtt
     2941 acatttcttt tatcataatc atatgttttt gtttgttcct tatagcaata tttttggtct
     3001 atttttttta ataaatcaga actgtatccc caaaccgaag aatcaataaa tgcagtaaga
     3061 ccaaaatttt caaatagcca tgatgcaaaa cgtatagcta atttttcatc agcatgagag
     3121 tgagatataa aaatatctgc ttttatagtt ggaaaccaat ctttaataat ttcgtctgca
     3181 tctagaattt tgctgtcctt agaataataa tcaactaaat cattttcact ttcaaataga
     3241 ttttctattc tcttgttaat agatttttgg ttgtgatcta tttgatttac tacatgtgta
     3301 tatgattgcg agcttgagga gaatgcattt aagtcagcat ttgtaaaatc caattcatat
     3361 gccttataca aggatatccc tccattcttg tattttgatc cacaatttat taggcaacat
     3421 aacagtatac cctatcgtta catatcccat tcattattat accagtattt cttcgtgaca
     3481 cataagggtg taacataata atttcaaacg aaatgactac aagtagtcat tgaagcaaat
     3541 cttcataaga cacctgtaga atatctttga tggctttcaa ttgatccaac ttaatgtgtt
     3601 ggcggccacc ttcaatctta accaacgttt ccctagttat agcaatttta cgaagctgta
     3661 ggtctctaat cagctcggtt tgaccaattc ctttttctaa tcggactcgt ctaatattgc
     3721 taccgattac attttcttta tcaataattt tttcctcttt caagaatagc acaccttttg
     3781 gactaaaatt agtccttttt cttattaatc ttaaagattc ggtatgctac aatgggacta
     3841 gtattagtcc atattcaatt ttaaggagga atttttttga agaaatttgc aatcattcta
     3901 acttgcgctt tactcatcgg aactataagc gggtgtacca cttctgacac aagttctaca
     3961 agtacggaaa ctagtacaac aacctcagaa aagaattacc caatacattt ttttccggtt
     4021 ccagatggat ttgaagctta ttatcatgat aaaaaactag atgttccttt atcagaaact
     4081 gaatctactg aaaagatttt gccaattgaa attgaaagaa atcaagacga tataaaacta
     4141 aaagctgatc ttcccttact gaacagcaca caaattgata gacatgaaaa tattaaagtt
     4201 aatattgaaa aaggagcgtt agcacaactt tatactgaaa aagttgaaca attttttgag
     4261 gctggtgcca ataaagactt ttcaaaaata agcgattatt cggataactt ttttaatgag
     4321 acccaagatg aaatcacgaa ctcaactttt atggctgaag atatgtacaa tatgaagttg
     4381 aaaaaaataa agtcgtatga ttatccatta aatctaacat taaataaagg gatactctct
     4441 tttgtattag caggttacgt tgactatgaa tatacagcag attatttgga gacgcccctt
     4501 caacacgata ataacgatat taattttaga tttatctaca attcaaaaag taaaacatgg
     4561 ttagttgatc aattgagcac tataaatacg ggatttcatg aattacctaa gcctgacaat
     4621 gaaactgctt tggtcattaa aacattctaa aaaagaaacg ttgaaggaat aattattctt
     4681 tcaacgtttc ttttattgtt tttcagttta cggtcttacc tgagcgaata atctgatttc
     4741 taaatgattg gaaaacttct tgtggttgat aataatctgt atctatttca aatgtttctg
     4801 agaataattc attgaatttt tctactgaaa tgatgatttt accattctcc tctcgactgt
     4861 tttctattat ttctgcctct aattcaaata aatctagtga cgaactaaaa tcataaatcc
     4921 tgtcatattg aacaaaaaaa tcaagaaaaa gttgctcaaa ctcttcctta tttatcacta
     4981 gtgtttcaag cggaacaact ttattttcat cagccattct tccaatttcc tcactttcat
     5041 tttcaattgt ccattgttgc ggacgtatca gattttctct atcatttttc agtgtataga
     5101 tcacttgtaa tacacaacaa tgctttgtaa acttattttt ttagttagtc gaatcttttt
     5161 aaatgtgcgt ttcataccat gcgcttgata tattttctcc tattttttaa atcgtttatc
     5221 acaactttta tcgttttttc ttctgaaaaa aatcttgttt acatcgttac atagtttcca
     5281 aaaagataca ttactagtag aaacaacaag attaatttta cttcccactg aaatgggaag
     5341 tatattttaa atattttttc tccttcaact tacactataa agtatcttaa tcacacgata
     5401 tgctagccac taaattcatc atatttgatt ccttttttaa gataatgtag catcttttta
     5461 tccaataacg caattgtttt taaggataaa tttcttaaga tggtacattt caaaatggca
     5521 tttgacatat gaaacaaaaa agaaagaaaa gagcataagg gaaaactgat agcaccttcc
     5581 tacaggaagg tggctaagtt ggctgtgcca actggttttc tttcaaaatc atttcataat
     5641 ttttgatatc ataaaaaaat ccattttgga cctattttcg gtcataattt agtacctact
     5701 tttggtcata gtttcgtccg tagttttggt catagtgact aaggcttttc tgttcacaaa
     5761 attggtttaa atttgctttc tttaacactt catttatatc atagcaatta taatgtttac
     5821 acaacatcat tcctaatttt aacggttgtt cctctttata ttttttaagt tctacatttt
     5881 tttgcgttta attacttttc tcttttcttt atattccgct ccaactttct ctttaatagt
     5941 gataatagaa ttacatattt ttgttaaact tccttaaaaa aattggatct cgattactca
     6001 aatttgcttg caggcttttc taattgcttt gttttttctt cctaattatt tgattttatt
     6061 tccattttct tctagtgaaa atttattatt tttaataatc gtacgcgtag aactgatttc
     6121 attttttgta tctgtttgat tatctaacgt ttgaaattca aagttttgat tggctttatc
     6181 aatatctttt tatactactt tatttgcaag atatattttc ttgcttaatt tggtcatagt
     6241 ttcattcgtc acttcggtga tattttttta atttgcaaat aaaaagagtt aaaccgatat
     6301 acattaggtt caactctttt gcaggtttca tgggtgtact atcactttta atctgataga
     6361 tgtaaacctc tctttatctt tttgttactt caattttcaa caatagctcc tttataggtt
     6421 gtcaatattg ctctacgtat tctggctttt taacccatta tttctctaaa gtggaagaga
     6481 ataatcgctt aatccccact aattccttgt cgtaaattca tgtcaaatac aatttttaaa
     6541 agccatttaa ttcatggatt atctcttcac ttttttctag ataacaatat ttcaagttgt
     6601 tttttatctc atgtttcatc tttaattctt cttgaatcat cagttcaata taattagtga
     6661 ccgtgatttt ttcatttgtt gcgttcttta ctgattcaca taattcgtca agttctaaga
     6721 aatcatgcgt actaatcttt agaattaatt tcatgacaat tccccctttt atttttttaa
     6781 tagattatcg aaaagcggat taggatcatt aagtgtatct ctgaataact cgttgtcttc
     6841 ataggtaaat cttcgtcttg gttttgatcc cttatcattt tcacggattt cactatcaat
     6901 aatcactgtt tcatgatttg aatcaaattt tttcgctgac tttctgtctt caacgatatt
     6961 gattttttgt gttttttctt tcatttctcc actatctttt tgaacgttct cccgaacatc
     7021 tactgttttg aatccttgac tacttgtaga actttgtaca ttctctctta catccattga
     7081 tttaaaccct tgactacttg tagaattttg tacattctct cttacatcca ttgatttaaa
     7141 cccttgacta cttgtagaat tttgtacatt ttctcgaaca tcaattgtct tagtaccttg
     7201 accatttgaa gagctttgta aattctctct tacatcaaca ttccgtccga catgaccatt
     7261 caatgaacct tgaatatttt ctcggacatc tactgatcgg ccaccttgac tacttgtaga
     7321 attttgtaga ttttctttga ccaatttttc taatccggta tttgagtttt tagcttcttg
     7381 gattctttct ttggtcaacg cttctttttc gtccgtatta gctcctgtac gcccttctac
     7441 acgtttcctt aacatttcct cacgattcat tgcttcaggc gtgtatttag cttcttgtcg
     7501 cttctgatta attaattctt cagcagactt agcttgaccg tgcatagcat ttttacgttc
     7561 ttcaatatct tgttgaactt tttgctgaat tgcacttaca ggattattat tcgattcagc
     7621 attatttttc attgcttcac gcatacgttc agaactagac ataattctat cggcattttc
     7681 aaccttagca ccatcttttc tatccgaaag acgtgttggc atggaatcag catattttcc
     7741 agtttcatct tctttatttt tagctaacat aggtttgcta tttttattaa tagcggacac
     7801 tgtaccatca tctaaacctt ctttgaactt attcttggta tcattagcca tatcacgcat
     7861 actcttaaat ggttttattg ctctttcact agccattgta gctccatctg aagctaaacc
     7921 tgataatcca cgttcatggg catatcccaa agctcttcca gttttgccag ctttttttga
     7981 tagagtttcg ccgaaattct tttctggttt tcgatcttct ccttctccac tgtctgatcc
     8041 atttccattt ccgcttcctt tagcacgatt aaatccagtt gatccttttc taaacagcat
     8101 tgcgcccata ccaaaagcag aagcaagttg cccatagcct tctttgagtc caatatcaac
     8161 accaaagtat ctcatgactg ttccactgcc ttttatcagc acaaacacag cacagatata
     8221 agcaattgtt tttataaaaa tatttgtgga gataccttgt ccagcattta aaaaattgat
     8281 aaacatagca aacatagata gtccaaaccc ttgaaatcca actgttaagt aacattgtaa
     8341 aatatcggat aaaacaactt ttgaacgttg tcctgtttca atatctgtcg caaaaacaag
     8401 aacacctaac acacgtttaa atgcaagttc taatattgct gtaatgatca caaacgcgct
     8461 gaacacatag gcgattgcca acgctgtcaa cccaatcgaa atcccccaaa gatttgcttg
     8521 atatcgataa taacctgatt tcaagctatc agaaaatgtt gataagaagt tatcagaaaa
     8581 ctttgtggca acaaattcat tattagaatt ttcaactaat tcatagcgaa gattatccgc
     8641 agctggattt tctttttcca atttatcaat cactttatcc gtcaacactt gtgttaaatc
     8701 tgtctgttga aaattttttc gtgttaactt atttcgatcc tccgttttat caatgcttga
     8761 gtattgatct gttttattaa tatatgccag atctgttact ccttgtttta tcaatgacca
     8821 agcgactccg tcatctgaat ttgtaatcgt agtagcatca ttgtaaaata ttttggcaaa
     8881 ttgaataccg ctagaaatca ttgttggcat taaaagaatt aacgctacag acatcactat
     8941 attcattcca acagatctta aatctattgt tccttttcca gtaatcatct tgtagccaac
     9001 aaacatcaat gaaaggatca ttaatccaac gacaattgta tttatgactg attgataaac
     9061 attatttagc cctgtacttt caatgaaatt gaacaaatcc aacacatctg gaatcatatt
     9121 ttgaatcgaa tcagtcacag taaacatgcc ttttaccaca gcccatccaa gccaaatccc
     9181 gaactgacta aggaaatctc cattgtattt ttttaggtaa ggtctataaa gagaattatt
     9241 caaaaactct gtttgacttt ttgtgtcatc aaaccaattg aaaatgctag cttcaacaat
     9301 attacttgta aaaacaacgc taatcattaa aacaagtaca ctgagtgcta accagtttat
     9361 ttttctacta acgatttttt ctttaattgc tttcatagtt ttctccttca gcccattttc
     9421 ttaggctctc agagagctgc tgagccattt tttgattaat tatgatatga gttacacaat
     9481 tgtcattttc agctcttaaa tcgagaacta ctgtgttgaa gcagatactc tcgattaatt
     9541 cgagagtatc tgtattttga tcaagacacc acatttgatc tattaagcga tttttaatca
     9601 tgattcttct cctttcaacc aattatgcat agtaatttca ggtaactctt tgatttcgaa
     9661 agcttttttg aactgatcta taggctctac attttctaaa aattgacttt tatatctttt
     9721 ctgaagtcca ttcaaaaaat atgttacata atcgtataac ccttcttcag tttttctttg
     9781 aaaaaagcat gcttcatgtt gttttataat acactcagca ataagatact gagtattttc
     9841 agataaatat tcaatgattt ttctgatatc ttctgtatct acattagcgt ttctcaaata
     9901 gtgatacact tgaaataatt ttcgaccatc ttcgttattt gcgtcataaa gaacactaat
     9961 cttactgtaa atcctcttta tattaatatc ctcttcttcc ataacgagag tagtctttga
    10021 tatgttctgt gaagtagtct ttgtatacgt atatacaaat ttgtacatac ctctaccttt
    10081 ttttaaagag acatatctct ttttttcgat acccctctga cgaattttcg gcatatactc
    10141 ctttttttcg caatccaaag taggaaaagt aatttctatc aatttatgta catttaaaac
    10201 aatgtacata acatttgata atgtaactgc tcttttctca taataaatat ttctaaaaac
    10261 ccttttgata atcccctttt tctctaagta cacaattgca tcttttatag ctcgttctga
    10321 taatcctgtt tttttgctta attgcttata tgatttttgc aaaatatctt caagaaactt
    10381 tttttgataa ccaagtagct gaccatcatc gttaaaaatt tttttaggtc tataccaata
    10441 ggtaatttct gctaagataa ctattgcatt caaatagggc ttctcaacac cttttttcgt
    10501 tttttttctt aattgatcgt accatgtgtg tggattacat ttccgtcaaa atttatttct
    10561 ctaagtttgt caactacaac atttccagaa gaaaacacct tttcaccttc ttttttgata
    10621 taatagctat aaataaagtt ttctcagcac tttattattg agtgttcccc cagtctgcaa
    10681 acttttggga acactttttt tcttttttta aagcattttt ttataatttc tacttcatca
    10741 tcttccaata ttttcccctc ttttcattcg agcaaacata aactcattaa ctgccttttt
    10801 cgaataaaat tttcttgccc ctaattcaac tacgggcaat ccctcatttc tcacagcatt
    10861 ttttaaaaag ttttcactca catttaagta ttccgccatt tctttttgat tgagatattc
    10921 ccttgtcatc cccgcatttt cttgagcctt ttcaatagct tttgtagcaa tttgataaaa
    10981 ctgctttaga aacatttcct cctgttcttc tgaaatcatt aattttattg cttccacaaa
    11041 aacctctcct ttttaattaa ttattctata actcctctac ctttataagt acaaataaat
    11101 acaaattgcg taaaaaaatg tatttatttg tatttataag aataaagtat catactccag
    11161 ataaaaagta aatactttta aatactttta ttttataaat atgatatact atctttaaaa
    11221 ataaaaagga gaaaaaagat gaagccaaat ccttcagaag caggaaaacg aatcaaacaa
    11281 ttacgccttt catgtggttt tactatggaa gaacttggaa ggaaaataga taattcacca
    11341 cgtgcgacca tatccaactg ggaacgtggg accaatttac caaatccaca aaagctgaaa
    11401 ttattatcaa ctatcactaa ttcaacaatt gactggatta aatggggaac tttagaagaa
    11461 tatataactt cataccttat cgatataggg tatgagctat atattaagga cttcccagaa
    11521 atacctcaca aagtctttaa agacattcaa gaaagatata gtgatacgtt ttcgctagat
    11581 aaagactatg agttattgaa tcctataata aaaaatatat ttacaaaata ttactcaaaa
    11641 gattttgaaa tttatctaaa tgagatactt gctaataata tcaatcctct gattgaagag
    11701 tacgctaacc aaagacactc tatctctaaa gagctatttt tcaaaagagc caacagtaaa
    11761 cttcaagaca agataagaaa tggtgatttc aaatacggtg aaaaagaaag aatgattgat
    11821 tctttaaaac agctattaga cgaaatggac ttagcctata aagatatttc aaagtattca
    11881 tctgtcgagg atttctttta taaaattact aaaaaccaat ttgaaacaga aaaatttatt
    11941 tcagatctta gtaaaaaata caatttccca tatgagaaaa atagtataat cgcaaaattt
    12001 ttaactgata atcacgataa atttaaaaat aattgattct tcaaataact tctctacctg
    12061 caataatgaa gtaaggagag aatcaaatgg caacattttt tagttataaa ttacaaaatg
    12121 gcgaaaaata ttggggattt gaaacttatt tagggaaaga tcccaagact ggaaaagata
    12181 tacgtacaaa gcgtagaaga ttcaaatcaa aagctgaggc gcaaacagca cttaatagac
    12241 tacttgtaga ctttaaagaa aaacaagagt ttaaaatcaa tgttacaact tttcaagagt
    12301 tgtatgaatt atggattgat aactacagaa caagagtaaa accgtcttct gttgccgttg
    12361 ctcaacgttt ttgcaaaaac catatattac ctgcttttgg ggaattacga ttggataaaa
    12421 taagtgttag ctattgccaa aaacaggtga atgaatggca caaaacatta aaacaatatg
    12481 gtttcttgag aaaaacaact gctcaaatat ttaaatttgg agtagcaatg gaagtctgta
    12541 aggataatcc tatgtctaaa acattgcttc caagaaaaat tgaagaagaa caacccttga
    12601 agttttacac gaaagatcaa ttacaactgt ttttacagaa tactaaagaa aataattcag
    12661 ttaaactgta cacttttttc cgtttattag cttatacagg aatgcgtaaa agcgaagcat
    12721 tggcgcttca atgggaagat atagactatt tcaataaaac aataacaatt ggtaaaacta
    12781 tcgctcaaga cgagtttaat caagtagttc tacaagtacc taaaactaaa aattcatcaa
    12841 gaacgattca gcttgatgat tttacactta aacaactgcg tatttggcaa caagaacaaa
    12901 tgaaaataat gatcttatat ggctataaca cgaattcacc aaaacagttt cttttcacta
    12961 caaacacaaa caagttgtac tacccccaag tagtaaacga ttggttagac tggatttaca
    13021 aaaagacacc gatggagcct caaattactc cacatggatt taggcatacc cactgtagct
    13081 tattgtttga aagtggtgcg tcgataaaag aagtacagga acgattaggt cataaagata
    13141 ttaaaactac catgaatatc tatgctcatg tcacaccaca atctgttaag aaaactggtg
    13201 accgatttgc aaaatttatg ggcgaataat tccaaacgta gccaaaaacg tagccaacca
    13261 ttaaaataca aataaaaaaa cgctcgaaac gctttaatat caacgtttcg agcaatgaaa
    13321 tagttattaa cctacagacc cttccatctc ataactgatc aatcgattga gttcgactgc
    13381 atattccatt ggaagttctt tggtgaatgg ttcaacaaag cccatgacga tcatttcagt
    13441 tgcttcagat tcggtcaggc ctcggctcat cagatagtag agttgttctt ctgagatttt
    13501 tgagactttg gcttcgtgtt ctaaagagac ttggctgttg tggatctcat tgaatgggat
    13561 cgtatcggat ttcgaccatt cgtccatgat gatcgtgtca cattcgatat gagagatcga
    13621 acccgcactg tttttggcaa aggttacttg tcctcgatag tttacttctc cgccgtcttt
    13681 tgaaattgat ttagagacga tagagctaga tgtatttggt gcattgtgga tcatttttgc
    13741 acccgtatct tggatttggt ttgctcctgc aaaggcgatg gagagcatgg tgcctcgtgc
    13801 accttttcca tctaagtaaa cacttgggta tttcatcgtt gtttttgcac ctaggtttcc
    13861 gtcgatccat tcaacggttg cgccttcgta tgcttttgct cgtttggtta ctaagttgta
    13921 cacattgtct gaccagtttt ggatcgttgt gtaacggcaa tacgcatctt ttcttgtaaa
    13981 gatttctacg atggcggcat gcaggctgtt acttgaataa gtaggtgccg tacaaccttc
    14041 gacatagtgg atgcttgctc cttcgtcaac aatgatcagc gtacgttcga attgccccgt
    14101 gttttccgca ttgatccgga agtacgtttg taatggaaca tcgactttga cgccttttgg
    14161 cacgtaaata aaggtcccac ctgaccatac ggctgaattc agcgctgcta atttgttgtc
    14221 ggttggcggt acaagttttg aaaagtactc tttgaataat tcagggtatt ctttcaaagc
    14281 agagtcagtg tcagtaaaga cgattcctaa cttttcgaat tcatctttca tattatggta
    14341 cacgacttct gattcatatt gtgcggaagc accggctaga taagctcgtt cagcttctgg
    14401 tataccaatc ttttcaaatg tatctttgat tttttctggt acgtcttccc agtcacgagc
    14461 gggtttgtca cttggttttt ggtaatattt gatggcatcg aaatcgatgt ctgaaaggtc
    14521 ggggccccat gtttgcattg gcattttgtt aaatgtttct agagatttca gacggaattc
    14581 aagcatccat tctggttcgc ctttgattct tgacatctca cggatcactt cttctgtcaa
    14641 gccttctcct gtactgaaaa ccggttcgac atcatcgtga aacccgaatt tatattcttc
    14701 taattctggt acgcccatgt tctcactcct cttccttgtg gtaatgatgg aaagctgcgg
    14761 taccatcgtt ttccattgct tttcctagtg ctttccaggc aagtgtcgca catttgatcc
    14821 gagcgggaaa tttagctaca ccaccaagca tagcagcatc gcctaattgg tcgggatctt
    14881 tgacttcttt tccttggaca agctgtagaa agtctacagt taaatgttct gcttcttcta
    14941 ttgattttcc gatgacggcg tctgtcatca tcgaggcact tgccgtactg atggagcagc
    15001 cactgccgtc aaaggcgata tttttgatga ttccgtcttt tacatcgact tgcaattcga
    15061 tcacatctcc acatgtgggg ttgttcaatt cgatcttgct tgtcgagtca gtcaagcttc
    15121 cacgatgatg cggatgggaa gaatgatcca agatcacttg acggtataaa ttgtctaatt
    15181 tagatagtcc catgttggaa aaactccttt gttgccatga ttgcttcaac taaacggtcg
    15241 gcgtcttgcg ttgtgttgta gaaataaaag ctcgcgcgag cagtcgctga tacttcaagg
    15301 tacttcaata gcggttgcgc acaatgatga cctgctctga cggctacccc ttccatgtct
    15361 aaagctgtcg cgacatcatg gggatgtaac ccatccaaat tgaatgcaac gactcctgtc
    15421 cgaaaattcg ggtcttgtgg accataaaca gtcaatccat caattgcttg taattttggc
    15481 aacacataag cggctagttc ttcttcatat cgatggatat tgtccatacc gagtttttgc
    15541 aaataatcga ttgcatggcc taatgcgata gcgccggcga tatttggtgt ccctgcttcg
    15601 aatttccaag gtagttcttt ccatgtactg tcgtataatt cgacaaaatc gatcatttcg
    15661 ccaccaaatt caacaggttc catttcttct aaccattttc gtttaccata taaaacacca
    15721 atacctgttg gtccgcacat tttgtgtccg ctgaaagcaa agaaatcaca gtctagtgct
    15781 tggacatcaa tggccatgtg cggggcagat tgagcaccat ctactacgat gaccccgccg
    15841 ttttcatgga caagttcagc taattcttga acaggattga agacacctaa gacattggat
    15901 acatgagcaa tggagacgat tttggttttg tccgtaatct ttttcgctgc atcctccata
    15961 tccaggaagc cttcttctgt tagttcgata tatttcaaga cagcacctgt tcgttttgcc
    16021 aactgctgcc acgggataac attagaatga tgttccatgt aagagagcac tatctcgtct
    16081 cctgctttga tatagcggtc gccgaaggtt ctggctaccc aattcaagct tgtcgtcgta
    16141 ccacgagtaa acagcacttc tgctgtttct tttgcatgga tgaacgcccg tactttttct
    16201 cttgcttgtt cataatcatg ggtcgcgcgt tctgctaacg tatggacacc gcgatgaaca
    16261 ttggcgttat cgtgttcgta atagtacgct aatgcctgga gtacttgttt tggcttttgg
    16321 gtcgtcgctg cattatccag ataaactaaa ggttcatcat tgacgtcttg aaataagata
    16381 ggaaaatcat tgcgtagctt tttagcatcg atcatccatt caacttccct tcgattactt
    16441 cgactaattc tttccgaact tgttctacag ggattgctgt taagacagaa ccgaggaatc
    16501 ctcgaatcac taagcgctct gcttcttctt tatgcaatcc tctactcatc agatagtaca
    16561 tttcttctgg atcaactcgt cctacactgg cagcatgtcc agcagttact tcgttttcat
    16621 cgatcaaaag aataggattc gcatcaccac gtgctttatc agaaagcatc aagacacgac
    16681 tttcttgttg ggcatctgca ccttttgccc ctttcaagat gtggccgata ccattaaagg
    16741 tcaatgttcc tttttctcgg atcactccgt gttgcaaaat atgcccgatc gtatgagggg
    16801 ctttattggt tactcgtgta tcgattcctt ggatttgtct gcccgagctg attgccacga
    16861 ttttgacttc tgcgtgtgca ccttctcctg ctaaatctga gtcaaagtca gcgatcacat
    16921 gaccgtcatt catgacacca attgcccagt cgacagaagc atctcgtaaa atgtgcccac
    16981 ggcgattcat ataagaagta atattttctc ctaattgatc tacggctgaa tatttgattt
    17041 ttgaaccagc tttagcgatg acttccacga tgatattacc tgatgatttt gctacttgtt
    17101 ctttggttgt ctggaaacgt tccagataag aaaattcact atgttcatct gccacgatca
    17161 acacatgctt gaagaagtgc tcatcggatg cgccatcttg aatgaataag gactcgagtg
    17221 gttcatcgat cacgacattt ttaggcacat acaggaaaat accgctgttc ataaaagcta
    17281 catggagtgc agtcaattgg tcttcgttca tgtttactgc ttttttcata taatattctt
    17341 ggactagttc tggatattcg atcattgcag tgaacaagtc ggtaaaaatg actccttttt
    17401 ctgctaattc cacaggcagt tgttcaaaaa tcgtccatga accttgttgg acaagcacag
    17461 gattgtcttt cattgcatca aatgccggaa tcgtgcctgt ttcactgatg gtttgtgttt
    17521 ctttcacatc aaataacgac cagcgatgga atttcacccg atcgatatgc ggcaatggca
    17581 gttcatctgc tttcgctagt gcgtcttgac ggaaggttct catccaatca ggttcgcctt
    17641 tacttaaaga aaaatcattt accgcgtcaa gataatcgag ccagtttttt tctttcattc
    17701 ttgctccccc ttacgcttct tcttctttat agtcgattcc taattcttta ctgataccag
    17761 cgtagccttc tgcttccaga cgtttagcta ggtcagcatt ccctgtcatg actactcggc
    17821 cttccatcat gatgtgaacg acatcaggtg tgatatagtt caataatcgt tgatagtggg
    17881 tgatgatcaa tgcaccgaaa ttgtctccgc gcatttcatt tactccttta gcaacgactt
    17941 tcaaagcatc gatatccaga cctgaatcga tttcgtctaa aattgcaaat gtaggttcta
    18001 acatcaacaa ttgcaggatc tcattccgtt tcttttctcc gccagaaaaa ccttcgttca
    18061 gataacgttc agccatttct tctggcatat ttagtaaagc cattttttca tctaactttt
    18121 tcaaaaatgc cataacagaa attttgtcgt tttcatcacg tttcgcattg atcgctgcac
    18181 gcatgaattc cgcattcgtg atacctggta tctcacttgg atattgcata gctaaaaata
    18241 agccaagtcg cgcacgttca tctacttcca agtctaaaac atttttcccg tcaaacaaaa
    18301 tttcgccttc tgttacttca tagtttggat tgcccatgat agcggcagat aaggtagatt
    18361 ttcctgtgcc gttaggtccc atgatggcat ggatttctcc ggttttcatt gttaggttta
    18421 cgcctttaag gatttctttt tcctcgatcg acacatgtag attttttatt tctaagacag
    18481 acatgcatta tacccccaaa ttctctttcg ttctcactca ttttagacta attgagaatg
    18541 aagcgcaatg accttcctta ctaaaatcaa atatctttta tttattatta aacaattttg
    18601 atttctaaat tagaataggt ataaaaaaga tgagaaataa gccattacag acttatttct
    18661 catctttttt gttccatacc ttattttgca tcagccttta ctggtttaac agagccgccc
    18721 catttgtctg tgatccattc ttggacttct ttgcggtgaa gcacttcaat cagttttttg
    18781 attttgtcac tgtcttcatc acctttacga gtcgcaataa tattcacgta aggagagttg
    18841 tccttttcaa gcaatacggc atcttctaat ggattcaacc ctgcgccgta agcgaagttt
    18901 gcgttgattg caactaggtc accttcatca ttttggtacg tagaagctaa aagtgatggg
    18961 tcgatcgtat ggttgaactt caagttctta gggttttctt caatatcatc gaatgttgct
    19021 gtttccagat ctactccatc tttgactttg actaagccag catcttgtag aattgtgatg
    19081 atgcgtcccc agtctgattc agaatttgaa gtaatgattg ttgcaccatc ttttaattcg
    19141 gaaacatctt tgactttttt agagtacaag cccattggtt cgatgtggac agcaccggca
    19201 ttgacaaagt catatccttt ttctttgatt tctttgttca aataaggaat atgctggaag
    19261 taattggcat caatgtcgcc ttcttccaaa gattggttcg gtaatacata gtcatcgaat
    19321 ttgacgattt caagatcgat tccttcatct ttcaataatg gtttcacatg ttccaaaatc
    19381 tctgcgtgcg gtgtcggtga agcgccgact ttcaatgtcg tgtcgtctgc tttatttgct
    19441 gaatctttgc tgtcgctgtt gttaccgcat gctgctaatc ctacagtcag caaaagcgct
    19501 gctgcaaatc caaaaatttt ctttttcata tcctacatcc ccctatatcc tattatcttt
    19561 tgtctgtttt cttagttaag aaatcaccga ttccttgaac gataaatacg attagtaaaa
    19621 taattaaagt cgcaacgaat gtcactgtta gattaccacg ctggtagcct tcctgccaag
    19681 caagacctcc aagtccacct gcgccgatcg cgccggccat cgcagtaaat ccgatcatcg
    19741 agatcgttgt aactgttaat ccagaaatca atgcgggaat actttcaggt atcaagacct
    19801 tccagatgat ttcccagtaa cttgctccca ttgcatctgc tgcttccagt acaccagggc
    19861 tgacttcacg aaaagcaatc tctactagac gggcataaaa tggtgctgcg gataaaacaa
    19921 gagctggaat ggctgcttgc gcacctagca tagtgcctac gattgcttta gtaaatggaa
    19981 tgatcaaaac catcaggatc ataaatggcg ttgaccggaa aatattactg atgatcgata
    20041 cgattccata aatgattcga gcatacggtt tgtttttgcg tccaatagag taaaggatca
    20101 atcccaaaac taatccgatg atcgtcacta agaccattga gattaatgtc atatatagtg
    20161 tatcaaggat agcctgattc atcgtttccg ggttgatttg tttaaaatct agatatgttt
    20221 ctgaaaagct tttatccacg atggatcacc tcaattccta ctccttgttc tttgatgaac
    20281 acttctgctt gatctaattc tttggtttca ccagtcatca agacagtcaa tgaaccaaag
    20341 gaaccttctt tcacttgttt gatctttcca tacacaacgt tgacatcgat gttatagcgt
    20401 cgaatcgctt gggaaatgac tggctcgttg gcatttcttt cgctaaaggt caaagttgcc
    20461 aaacggccgc ttggattttc tttgatgagt tcagctaata gttctgtcga atcagcttct
    20521 ggttcgatgt cttgttgtac aaagcgtttg gttacttctt ttttcggttg tctgaagaca
    20581 gtcaatacgt ctccttcttc tacgactttc cccaactcca tcacagcgac tttgttgcag
    20641 attttgcgga tcacattcat ttcatgtgtg atcaagacga tggtcaaatt caatttctta
    20701 ttgatcgcta acaataagtc taatacttct tctgttgttt gcgggtccaa tgcgctagta
    20761 gcctcatcac aaagcaggat ctcaggatca tttgccaatg ctcgtgcgat accgacgcgt
    20821 tgtttctgtc cgccggaaag ttgtgaagga tatgcttgtc cgcgtccttc taacccgact
    20881 aaacgcaaca gttcttctgc ccgttcttta cgtttgctct ttggtacgcc agctaattcc
    20941 agcggcagct ggatattttc aagtacagtt cttgaccata acaggttgaa atgctggaag
    21001 atcataccga ttttctttcg gaatgtacgt aattctttgt tttttaattt tgtaatatct
    21061 tgatcgttta cgatcacttc gccgctcgtg ggaagctcaa gtccattcag gagacggact
    21121 aatgtacttt ttcctgcgcc agaatagccg acgattccat aaatatcccc tttttcaacg
    21181 tttagtgaaa cgtcattgac ggcttggatg tttccgtttt tcccattgaa tgtctttttg
    21241 acattcgtta gttggattaa tgacatgcca ttcacatctt tctcttataa tttttcaaac
    21301 aaaaaagcct tcgccctctt gccttaagca aaaggacgaa agcttgaact tccgtgttac
    21361 caccttgatt taccgttact tcgcaataac agcctcttcc agtacttgga cttagcttct
    21421 ttccgtatac tgtcgcgctg taacgggcac tcccgtagta agtttgctta cgctcgctta
    21481 ctctgctcta agaccatctt ccatctcatt ttcgttaccc attttcagca aacagggctc
    21541 tcttcaaacg tccgtgacat gtactcttct tttcaaagct ttctcgtttc atataggatt
    21601 gcttatgatt atagcaactg gaagaatcag tgtcaacttt tttcaagtga ttttctgatt
    21661 ttataattcg tcaaattctt ttggatcaac atctttgaaa cttaagatcc acgcattcat
    21721 ttcatctgaa tcattcaaga tattgatatc ttcaccgatt ttatcattaa cagaagaaac
    21781 tgtacccgtt agcgggctgg caaattcatt gaccgctttt tccgcttcaa cttcgatcag
    21841 aggttcatct ttttttagcg attgtcctgc ttttggcaga ttggcaaacg tgatgtctcc
    21901 aagttcttct tgcgcttcat ttgtcaaacc aacacagtat tcttttccat taaataagat
    21961 ccaaaggttg tcctttttct tcaaatgctt gcctgccatt ttatatcagt tctccttcat
    22021 aaattttttc attgaatcca attgcaacaa gctggtcctc tcgtaagatc agtggtcgct
    22081 tgatcagcat accatctgtc gataagactt ggctcgcttt tgaagccgta aactcgccta
    22141 cttgatcttt cagtccaagt tcccgatatt tcatcccgct tgtgttgaac aggcgacgga
    22201 ttggtacttg actcgtttct agccaagtct caatcgttga ggccttcggt acttctttga
    22261 tcatatcaac ggtttgataa ctaacgccat gctggtctaa ccacgctttg gcttttttgc
    22321 atgttgaaca tttcgggtac cagtaaaagg tgtacaattt tcttacctcc ttgaagatct
    22381 tgcaggtgct tcattttggt atctcatcga taatatcaac ccgataccga tcatgttccc
    22441 taaaatcgag gatcctccct gactaatgaa aggcaatggg atccctgtta aaggaagtaa
    22501 tccgatattt gctccaatat tctcaaagac atggaacagc agcatcatga tcaaaccgct
    22561 tgcgatatag gcgtaaaatt cattattcgt atcgaaacac acccgaatca tacgatagat
    22621 taaaataaaa tacaagaaaa tgacgaatgc accaccgata aagccgaagt tttcaccgat
    22681 aacggtaaaa atcatatcgg actcacgaac aggcacatag atattgctta cgttgaatcc
    22741 tttaccaaac aagccaccgg taccaattgc caaaagtcct tgggccggct gataactcat
    22801 tcctgacgta tcatggaaag ggtccagcca tgaatcaata cgtgcaaact gataagattt
    22861 gaatccaact ttataaagca agtctcttcc gccttcagtc gtaaccaaga agatcgttcc
    22921 tgctccaacg actactgcca agattactac aggtgcgatg atgcgccaag agattccaga
    22981 catcaggaaa atcccgccaa agatcgcaag aaagacaagc atcgttccaa agtcatcttg
    23041 ggccatgatc aatgctaaaa ccggtattgt cacgatcaag agcttcccaa tcagccaaaa
    23101 gtccgatttc atcgtccgtt cttttacttg cgtattatgt ttagttacga tcagtgccat
    23161 catcaagatg tacgcaatct tcatcaactc tgctggctgg aaagtaaacg caccgaatcg
    23221 aaaccagttt ttagaccctg ttgaagcagc taaattctga tcatagaatt tgagcaagag
    23281 tcccattacc actaacccca aaccataaag gtaaggagtc agtttccaga tccatttgga
    23341 attcaaatgc atgatgacaa cgattgctgc cgctccaact aaataccaga caacttgcat
    23401 ccctacgcct ttcaagactg ctggattgtt cggatcatgg ctaagtgcta catataatga
    23461 gagcagacca atcaaacata acagaaagac tggtaaaatc acgccataat caatacgatt
    23521 atcgttcgaa gcttttaatt ttttttccat gtttcatccc ttttcttaaa aaccatactg
    23581 ctgattatta tagcggtcca gttagataat ggaaagtctt tccatagaca tttgggaaaa
    23641 attaactttc cgtttgtgca gttgcttgag caaatgcagt acaaaagcct actgcttatc
    23701 tttagtgtat catagaactt tttttgatac atgcaattat ctaccagctg agattctcct
    23761 cgctgtgaga agtttctgtg ctttcattgt atcgaaggat ctcttcggca atctctagca
    23821 gctgatcaga aaccagattg gttcgttgga tgaaataaaa atatcgatgg aaattcaacg
    23881 gagtcattgg cacattttct ggaacagagc gcttagacaa aatcgagcga ccgattcctt
    23941 ccttcagcaa cgcaacaatt acatcgttac ttttcacgat catcttctta tcttggatat
    24001 tcatctcttc aaaataacgc tgcgtgtaat gaaaaacacc agagtttgct tctcttacaa
    24061 gccacaattt gctttttggg tccccagcga tgactagctg gtcttccatc aaagagtatc
    24121 tttgtacgcc ggaagtctct aatggctttt cgataaaacc aaaatcggat tcatgtttcg
    24181 ctacttgttc taatgattca tgagaattcg tgatttcgat ctcaaaatgc actttaggaa
    24241 accttttgat cagatgtttc atcaactgag gcaaaagata gacagcaaag gtgtgggaag
    24301 caacgatccg acatacttct tcttcatttt gttcattgag caatttttgc tgagtttctt
    24361 cccattcttc taacaaaacc agtgtccgtt catataataa gtcggcttgc ttagttggaa
    24421 gcatctcttt tcttccgtta cgttgaaaaa gatcgatatt caattcccgc tccaactgtt
    24481 tgatttgatt cgagactgct ggttgagata aaaacagtac ttctgctgct ctggaaaaat
    24541 ttcttgtttc atatactgct cgaaaagtcg ttaataactt aaacatggca ccacttccat
    24601 aactttttat gataattact ataaaaacta tttgatttaa atatacaaaa aaccatctat
    24661 aatagaaatg tacaacaaaa cagttgctga tccaactagt aacttagatg aagacaatca
    24721 gctgtctgct tgctcgtaat catacattcc tattcatttt acaatgtatt cgttcatctt
    24781 ggtactaaaa tctattaaat aaaaaggaga atattatata tgaagaactt tttgaaaatt
    24841 attccgatcc cgatctgcgg gttgatcctt gggttagctt cccttggaaa tctgtttaaa
    24901 gactatcacc atgttgcttt aggcaatcta actggcggta tctctatgat tcttatgata
    24961 ttcatttttg ttaaattgtt tatcttattc gaacacacga aacaaacgtt gcatgatcca
    25021 atcatcgcct ccgtttcacc aacttttacg atgtcactca tggttatttg tacttatttt
    25081 gtttcatatg aaagtattgc accaattgtc aaattcattt ggctgtgcgc tgttatcttc
    25141 caagtgatcc ttgtctttta tttcaattat caccatgtta tcaaagctga tctttcaatt
    25201 gaagcaattt atccaagctg gtttatcatt tacgttggat ttggggtcat cactgtaact
    25261 gccgggaact tcttcccact tattggaaaa attttctttt ggatttcatt gatctgctat
    25321 gcgttcttat tgccgatcat catcaaacgt gtctttttcg taagaaatat ggctcatccg
    25381 acacgtccgc tgattacgat cgttgcagca cctggttctc tttgcctaac aggttatctt
    25441 aaaaactttg ctgaacctaa tttttatctt gtcgtagcat tgttcgcttt atctcaagta
    25501 ttgtatttcg ttgtgctgtc tatgcttcca cgtttgttca agcttcgttt ttatccaagc
    25561 tatgcagcct ttacattccc gcttgttatc tctgcaacag ctatatttac tactgttcat
    25621 tacttcaaca gtttaggtat ctatagtagc gtattggatt tcttaaaagt tgcggaatgt
    25681 ctgtttgcaa gtgtagttgt cttctacgtt cttgctcatt acgtacgttt cttaattaaa
    25741 gaacatagca aacatggaaa atttgtttct aaaaaaatcg cttaataatc gattcaatag
    25801 gttgtgaaaa agctgttctg catcaagtaa taagaacggc caaacaaaaa cagctgttca
    25861 tgtttttgta ctggttgggc ttattaccgc agatgcaagc ttttgaacac cgtttaccaa
    25921 gaggtcgtaa aagaagtggt cagcttcaag aaataagaag gaatttacga aaattgcttc
    25981 tcaaattttt gtgaaatttc ggcttatttc cgtagaagct acttctggaa caccgtttat
    26041 tcgaaacaag aggtcgtaca agacttttgt cacgacctct tgttcttttg tcaaaatact
    26101 ggtttagtgc tactatgttc gagtatgctt ttagtattta ttgacgaaag gaaccgatca
    26161 aatgaaatca ttgtcacatc caataaaatc tgtaaaggat tcagcggtcc gcgaaatctt
    26221 acccggttta ctgctttctt ttgccatcgc tgccttcagc aggcttcttg ctatttatct
    26281 gccacagtta ggtggagcga ctattgctat tttattgggt attttattag gaaatacttt
    26341 ttttaaacag cctgttctag caatcggcac aaaatttgct gaaagcaaac tattagaatt
    26401 ctctgttttt ttactaggtg caactgtcac agctcaaacg attgctcaaa ttggtgtaaa
    26461 aggaattgtt tttgtgttac tgcaaatgtc agtcactatc atcggtgctt acttgattgg
    26521 taaaaaactg caattcagcg atacttcttc tttgatgatg gctggaggaa acgctgtttg
    26581 tggttcttct gctattgctt caatcgcccc ttccatccat gcgaaagagg aagaaaaagg
    26641 acagatcatc acactagtca atctactggg tactgtgatg atgttgactc tcccttttct
    26701 tggattacag ttgtttggtg gaaatctcat tgaaaaaagt gcacttttgg gtggtacact
    26761 ccaatctgtt ggtcaagtag tcgctggggc aagcttactt gacaattctg ttgtcgaatt
    26821 cgccatgcta tttaagattc tacgtattat gatgctcgtt gttgttgtct atctgtttga
    26881 aaaattcatg cacaagaaac aaccagctct gtttgaaacg ccaactgata cgcagaaaaa
    26941 acgaaaatta ccgcttcctt ggtatgtatt agggtttgtg atcttttgtt tggtcaacag
    27001 cttgttttct ttacctgtag ttattgacca atcggcacat tttatcagca gctggtttga
    27061 gatcactgct ttagcggcaa ttggtctgcg tttagacttt gcaaaattca tgaaagaagg
    27121 tacacgcttc ttatcttatg gattagctgt cgggcttctc caaacagtga tggctttact
    27181 atttatttgg ctgatcaaag tttagaatga acatgaaaaa acagttgtga ttctcgcatg
    27241 gaacaatgtc cgaatcacaa ctgtttttaa ttttgcagat atccttctaa caacaacaat
    27301 tggcgtttga tttcaacccc atctattgcg tttcccatat atcctgtcag ttttccattt
    27361 tgcccgatca ctcgatgaca aggaataacg attggcaatg gattggttcg atttgcctgc
    27421 ccaatcgctc gcacagcttt cggactatca acagcaacgg ctacttcttt atacgttcgg
    27481 atttctccat aaggaatggt cgacaaagct ttccagacat tttgctgaaa aggcgtacct
    27541 ctctttatag ataaaggaac atcaaattct tttctttttc ccgcaaaata ttcttcaaac
    27601 tgttcttgtg tgcgcgttaa aattcgctga ttcgctgatt cgctttctga aattggctga
    27661 aaagatacag cagtcaatcc ggattcatct gcatctaacc ataaaaagcc gataggtgtg
    27721 tgtattttca ttttgtttgc tcctagtcaa tagactggaa cttcctcctt tttctctatc
    27781 caaaactact tgccaactaa taaaaattgt tcttaaaagt ttgataaacc gaggaaacat
    27841 ggtaaactaa atacgttagt ttacaaaaag aatacctgtt cttttacgta aaatcaaatt
    27901 ttaaaggtgt tatttaaggt ttattaaatt ttgaatgtaa accatatata aacatacgat
    27961 tgaaaggata gaaacgatga aagtatcaat tgttgtccca tgttttaatg aagaaaaaac
    28021 tgttcctctt ttttttgatg aggttgaaaa attcaaaggt gcccatgagt tcgaatattt
    28081 gtttattgac gacggatcaa aagacggtac gttagcagca atcaagaagc tagcctcagc
    28141 ttatccttat gtccgctttg tctcattttc cagaaatttt gggaaagaag cggctctgta
    28201 cgctggattg caagcttcta caggagattt agtgaccgtg atggatgttg atctgcaaga
    28261 tccgcccgaa ctgcttcctg agatgatcaa ccggatcact acttctgata tcgattgtgt
    28321 cggcacccgg cgttcgactc gtgaaggcga gcctgcgata cgcagtttct ttgcgaaaaa
    28381 attctaccag ttgatcaata aaatcagcga tacagaaatg gtcgatggcg ctcgtgattt
    28441 ccgcttgatg actcgtcaaa tggtggatgc cgtcctagaa ttaacagaat acaaccgatt
    28501 ttcaaaagga ttatttagct gggtcggatt taaaacagaa tatatttctt atgaaaaccg
    28561 cgaacgtgtg gctggcgaaa catcttggtc cttctggaaa ttattcaact actcgattga
    28621 tggtatcgtg aacttctcgg atgcaccgtt aacgattgct tcatttatcg gcgctttgtc
    28681 ttgtgtcggt tctggtattg caattttgtt cattattttg cgggcattgt tgtttggtga
    28741 tcctacatca ggatggcctt ccatggtctc gatcttcctg ttcattggtg gaatccaatt
    28801 gttatgtctt ggaatcatcg ggaaatatat tgggaaaatc ttcttagaaa cgaaacagcg
    28861 tcctgtttat atcataagag aaacagaaaa agtgaagcca aatgaattga agcctcacca
    28921 ataatatacg tcaaatgaag taaacatttt tttaaatgaa aaaggactgt gacaaaagtc
    28981 ttgtcacagt ccttttttcc gaataaatgg tgttccagaa gtagcttctt cggaaataag
    29041 ccgaaatttc acaaaaattt gagaagcaat tttcgtaaat tccttcttat ttcttgaagc
    29101 tgaccacttc tatcacaacc tctttcatat cttattactt cttcattgct gcttttagtg
    29161 ctgctgctaa tgggctttct tctggttctt ctgcttgtgc atattttttc agcaagcgtc
    29221 gttcttcatg tttggtcatt ttcttcttct gctctttttt atcaagcaat ttttctgtcg
    29281 ttccatcgta tttacaacgg aaataagcac cgtttttacc ttcgatgatt tccattttcc
    29341 ggtgacattg cgggcatcga tgattagaga cttttggatc ttttcttctg cggtagttgc
    29401 aatctgaatt ggtgcagaca tagattttgc cgtcacgtgt gtttttctcg cgcagattgg
    29461 ccccacattc tgggcatttc ttttgggtaa tcgagaaatc ttgatattct tgtttgcttg
    29521 atttgatctc attcaccaag cgttttgttt ctttttcgat tccattcaag aaggttcctg
    29581 cttgtttctt tcctgcagca atagcttcaa ggtctttttc ccagctttct gtcaaatctg
    29641 gtgttactaa agagggattt accaatacta ataattgctt acctttagga gatacttgca
    29701 gtccttgagg ggtacgttcc atcagttcag atttgattag tttctcgata atctctgcac
    29761 gcgtagctgg ggttcccaga ctgtattttt ccatttgacc aagcaagctt gcttctgaca
    29821 atggtttagg cggtgcagat agttcttttt tgatggcgaa atcgggattg attctcattc
    29881 ctttttccca tttgactgtt tccgtctcag tttcagtttc gcctttccat cctgcttgga
    29941 cgacacgatt ttgccgaaaa atgaatcgtt ctttaccaaa ttcaaccgta acttttgttt
    30001 ggctgacttt atggggttga gcaaacagtc ctaaaaaacg agagacaatc atttgataga
    30061 tttttcgctc ttcattactt aatttttcat aacgtgctct gttttcagtt ggcaaaagtg
    30121 catggtgatc ggtcacttta ctgtcttgga atacttttgt ctgttggacg atggctccgt
    30181 ttttcaaata ctgcttgacc tcaggagcaa agtcgctgac tgcttgcaat cgttctttca
    30241 tcgtactttt catgtcattt gtcagatatt tgctgtctgt acgcggataa gtaacgatct
    30301 tatgggtctc atacaaactt tgtacaagac ttaatgtttt ctttgcagaa tagccatagc
    30361 gttgattggc ttctctttgg atctctgtta aatcataagg caatggcgca gattccgttt
    30421 ttaatttttc ttggacttct gtgacagttc ctttgcttgt actgatcaat tgaacaagtt
    30481 tttgtgcttc ttcttgtgtt tttaaagcaa attgattttt ttgaagcatt ttggcttgtt
    30541 cttttccagc ttgcaacgtg atcgtgaaat acgtttgtgg acggaactgc tcgattttct
    30601 tttcttggtc tctcactaat gctagtgtcg gtgtctgcac acggcctgct gataaattat
    30661 ccgcgtactt cacagttaag gctctggtca cattcaatcc taccagccag tccgcttttg
    30721 cccgggcaag agcagattca tacaatgcat catattcttt cgcaggtctt agttgcttga
    30781 atccagtttt gattgcttta tctgtttgag aagagatcca taaccgcttc actggtttat
    30841 tgaaatgcac atactctaag atccagcgag caacaagttc cccttctctt ccggcatctg
    30901 tcgcaatgac tgcttctgag acatcttttc gctgagccag ctgcttgatt gcttttaatt
    30961 gatgtcctgt tttaggaagt ggtttgattc ctagtttttt agggatcatt ggcaacgtgt
    31021 ccatttgcca gctctgccat tccttattca gatcttccgg cattttcaat cctaataaat
    31081 gaccaagggc ccaagtaacg atcaccttgg gtccttcata ataatttttg tgcttttgat
    31141 tagcaccaag caccttgctt aggtctttcg caacgcttgg tttttccgct agaattagtt
    31201 gtttcataaa attcctttct gctttctact gtgatgggct gatgattttt caacaacgca
    31261 agtcccttgt attgctgtaa atcatcgtca cactcttcac accagcgctc atctccgtca
    31321 ttccaaaagg cgctgagaaa gttacttttt gcattgatat attcataatt ttgatggatt
    31381 tcgttccatt gtttttcgta cgcttgtcgt gcttcttcga aagactcgaa tgtttcttct
    31441 tcttcaatat cttcttccca gtcttcaaaa aaccaccaag gctcattgtc cccgaacatg
    31501 gtaattactt gatacatact cgtgctcctt ctttcagctt ttctagactc atcttagtca
    31561 cttttcaaga aagttgcaag aattttctct tataaaaggg tcatttaatg aacatcttaa
    31621 aattgttaca aatgaatctg attgtttaag gcaaagtagc gataaagtta ttgatcatcc
    31681 aaaaatagct gtcttctgga tcgattgttg gttcttttgt aaagtatcct aaaaaacgta
    31741 aggaaagata accgtggatc atactacgaa gttccctgct tcgatgaact ttttcttctt
    31801 tcgttaattg aaaagcctca aatatctgca aaatgatctg attcgtttca tggattccat
    31861 ctaataaaac agcttcattg gtatgcggta cactgatcag taactcatac actgcttgat
    31921 ttgaaaaagc aaaggatcga taagtttctg catagatctg cagtgcttcc tgaccacttt
    31981 ttcccacaag agcccgtcgc agctggtcat taagttcctg cagaagtttc gctgttagcg
    32041 ctgttttgac atcacgaata tttttgaaat ggttatacag cgagggagcc ttgatatcca
    32101 agcgtttggc taaatgctga aaggttattt gctgaacatc catctcttct gctagttctc
    32161 gaaagcagtc gatgattttc tcttgagaca gatttctttt tttcatttcc atgtttcctc
    32221 tcataaaata aatccttcac tctttcagtt taccacgaaa aagaaagaga aaaaagagac
    32281 tttcattgat aaactacata ttgtagttta taataaagag ctgtagatga aaattttcag
    32341 aaagaaggag tctaattggc tgcaagaata aaggaaaaat tatttaggaa aagagaaact
    32401 tgggaacaaa acttgtttgt cttatggttt ggaacattta tggctggtat cggatttagt
    32461 ttagtcatgc cttttatgtc actttacata gatacgttag gtaattatag tacgtcacaa
    32521 ttgaactttt ggagcggatt gactttttca tctactttct tggtgactac gcttatctct
    32581 ccttggtggg gaaaattagc cgaccaaaaa ggaagaaaat tgatgctgtt gcgtgcttca
    32641 ttaggaatgg caatcgtcat ttctttgatg ggttgcgtga ctagtgtgta tcaattagtc
    32701 gcattgcgtc tgcttcaagg gattttttct ggttatatca gtaatgccac tgcccttgtc
    32761 gcaactggga cgccaaaaga aaaaagtggt caagttcttg gaaccttagc aactggttct
    32821 gttacaggaa cattacttgg accgcttctt ggcgggatct ctgcttcagc gtttggctat
    32881 cgccctacct ttttcattac agggatcatc ttatttttcg tcttcttgtt gagtctgttt
    32941 ttcgtccatg aaaaatttgt cccagtgaaa aaagaaaaca tggtttctgc caaacagatt
    33001 ttcaaagact tgaaatatcc acacgtcgtc atcggtatgt tcgtcacaac gatgatcatc
    33061 caagcatcca acaattccat tagtccaatc atcagtctgt acattcgcca attgctgcat
    33121 ggacatggga atgttacgtt gatcagcgga atcattgctt cgatacctgg gattgccact
    33181 ttgatagccg ctccaagatt tggtcgctta ggtgacaaga ttgggagtga aagaatactt
    33241 gcgattggtt tgggttttgc gattctggtt tatatcccaa tggcattcgt cacgaatgtt
    33301 tggcaattag ctgccttacg ttttttgatt ggtatctctg atgcttgtct gctccctgct
    33361 gtccaagcat tgatcacaaa atattcgcct catcaagctg ctggacggat cttcagttat
    33421 aaccaatctt tccaagcaac tggtaacgta gtagggccta tgatcggctc cagtgtttcc
    33481 agtgcatttg gttatcgcgg cgtctttctt tcgacttctc ttcttgtttt ggtcaacttc
    33541 ttgcttgtac gacacaatac acaagagatc catcagcaag aaactgcaga agaaaaagct
    33601 tcaggagtct ccatagcttc agggcactct ccttctcata gacaataagc gtaaatgaaa
    33661 aacactgctt gaacagttgt cacagactgt ccttgcagtg tttttgttta ggcctgtttt
    33721 ttcaagaact cagataagag gaataatccc ttttccaagg tttctttttt acaacagtaa
    33781 cctagtcggg catgcttcgg taaatcaaag gcacttcctg gtactaatag tactcctgtt
    33841 tcttctaata aattgataca aaatgtctgg tcatcttctt cgatggctaa tttaatgaaa
    33901 gaagtagaga cgtaattggg agcgacaagt tcaactttcg gttcattggc tacccattgt
    33961 tttaaaatca caaggttctc tgtaatgatc tttttgtttc gcgccaatat tttttcttta
    34021 ttcttcaatg catgtacagc aagatcatct gacaggactc cgccgcaaat catcgtgtag
    34081 tctcgatact ttcgaaaaac ttctgccaac tcaggtccag tagctgtcca gccaatacga
    34141 atacctggaa tggagtaggt tttggatagg gaattggttg ctataccttt ttcatagaca
    34201 tctacgatcg acaagaattc acctttatcc gttaaaggcg catatacttc atctatcaat
    34261 acatatgcat ctactgtacg agcaatttct gcgatttttt ctaaagtttt ccgatctagc
    34321 aatgtgcctg taggattgtt tgcactattc aaacagatga tttttgtttc aggtttgact
    34381 aaggcttcta gctgttctaa atcaaactgc caatcttctt cttccttcaa atgaacaaag
    34441 tcaacagcgg cacctaaaga tttggggatg tcatataatt gctgataagt aggaagcatc
    34501 gaaacaacat ggtctcctgc ttccactaac gcgtatagag ctaaaagatt agcaccagtc
    34561 gctccattcg tttgtaagat gttttccgga tcgacggttt gataaagaga agcgacttct
    34621 tgtttgaaaa catctgatcc ttcgatccag ccatagtcca atggttcgtt tttgcgtttt
    34681 tcgaaaaatt tacttacgct agtcccatct aagccaacga gttcgtctaa tgtcaatgct
    34741 tcgatcgagc tttgtgcaat atcatatacc gctttctttt cccatttatt tagccattct
    34801 tctacaccga aatttgcgat tttcatgttt ctttccccct tatatcttga tccagcctac
    34861 agcaagcaac ccgattgaaa gcagtgcggc cacacaaatc agcccaatca ttactttttc
    34921 ttttcccgta atttgatgtt tggtttcacg acaagcgatc cagtagaagc aaaaaccagg
    34981 aagataggca atactacata aaaggacata agaaaatcct gctaaaatga tgcccatcaa
    35041 ttcaaaaact acagcaatcc caccgatcac tacttgtttt ttgattcctt cttttaaaga
    35101 aaactggact tgatagatcc cgacaagtag ataacaaatc aaaattgccg ctgtacataa
    35161 agaataggca aattgatagg cataatcagt aactaagaaa gtcaataaga atagattagt
    35221 caagattgca gtaacaacta acgaataagt tggggcattt tttttattcg tttttcccca
    35281 acctttcggc aacagaccgt ctcgagccat caacatcgtt gtttctgctg ggagcatcgt
    35341 ccaagacaac caagaaccaa tgatcgaaat aatcaagccg atattgatca gcgctgctcc
    35401 ccaatttccc acgattcctt ttaaaatatt tgccatagca ggttgtgaaa tagttgctaa
    35461 ctcttcttga gataagacgc cgtatggcaa gatcgaagca aggatataga taaacaataa
    35521 acaaagcaga ccaatgatcg atgcttgctg ggcttctgaa cgtttcttcg cgcggttggc
    35581 taaaacactt gcgccttcga tccctacaaa gacccacatc ataaccatca aacaaccttt
    35641 aatctgcaac cagatcgttc cttgctgccc tgttccattc actagattat cagatacgtt
    35701 accccaaaaa tcagcagtga atatattcac tttaaatgcg ataaatacaa atattaaaaa
    35761 taggaataat ggcactaatt tacagatcgt cacgattgta ttgatgacgc tcgctccttc
    35821 aactccattg tttactaata aagtcagacc ccaaataaaa atacttgcaa ataaaataga
    35881 aggaacattt tgtccacctt tgaatatcgg gaaaaattct cccatggcgc tcatcagcat
    35941 cgttgcaaaa gcaacatttc ccagccacgc agacaaccag taaccccaac cactgatgaa
    36001 gccacctaat ttaccaaatg aagcttccgc gtaaccgaaa ataccaccat ctagatctgg
    36061 acgcttttct cctaaatgat tcagcgataa taccaaagct aaaataccaa tcccaacgat
    36121 tatccatgaa aggatcgctg gccctggagc tgcagaacta gccagatcac ttgtgatccc
    36181 aaacacaccg cttccgattg acgaactgac aaccagagca accagtcccc atttgctaat
    36241 acccgtcgat ttcttttcca tttccatcac cctcacttat aaaattgaac aaatcacttg
    36301 caaaagattc ccttctattt tgcaactgct cttgcttaac aaaaagcaac tttattcata
    36361 ttattggata ttatgaactt tttacacaag tatttcaagt ataaaatgaa taaaaattaa
    36421 ttttattgca aaaaaacagc tatgctatcc aaaagaaaag gtgtttcttt tgttagccat
    36481 agctgttttg attcatttaa tatcgcttaa acgtattgta aaacttttgt ttcttgatat
    36541 gcgtggtcga tcaaaccacc acccagacat tccattccat cataaaatac aactgcttgt
    36601 ccaggagtga ttgcacgtac aggttcgtcg aatacgactt ctgcacgatt atcatccaat
    36661 aagcgaactg tcacaggaac gtcttgctga cgataacgga atttcgctgt acacttgaat
    36721 tcttttggca ttggttcatt cgtcgtaaag tggatttcac ttgcatccaa gcttgtggca
    36781 tacaatgcag gatgatggaa cccttgcccc acatataatg tgtttgtcgc tagatctttt
    36841 cctacaacaa accagggttc ttgcgaatct cctccgccac cgatccctag tccttgacgt
    36901 tgaccaatcg tataatacat caagccagca tgttgtcctt tgacttcacc atcaagagtg
    36961 accatatttc ctttttttgc tggcagatag ttgctcaaaa attgtttgaa gttcttttca
    37021 ccaataaagc agattcccgt tgaatctttt ttcttagcag tcgcaaggcc tgcgcgttca
    37081 gcaattgccc gtacttctga tttttccatg ccgcctagag ggaacatcgt ttttgaaagc
    37141 tgttcttgtg ataattggct aaggaagtaa gtttgatctt tattattgtc tactccacga
    37201 agcatgtgga ccacgccgtt ttcatcgcga gtgacttgcg cataatgtcc agtagctaca
    37261 taatcggcgc caagatccat tgcataatcc aagaatgctt tgaatttgat ttctttgttg
    37321 cacatcacgt ctgggttagg tgtacgtcct gcgcggtatt cggctaggaa atattcaaat
    37381 acacgatccc aatattcttt ttcaaaattc acagagtaat aaggaatccc gatttgagca
    37441 gctactttcg ctacatcctt ataatcttcc gtggccgtgc atacaccgtt ttcgtccgtg
    37501 tcatcccaat ttttcatgaa tattccgatc acgtcgtatc cttgttcctt taacaaaagt
    37561 gctgttacag atgagtcgac accgccgctc atccctacga caacgcgtgt tttgctgttg
    37621 tctgtcatga tatcaccatc atttcaatta gattctgaaa catctacgag ttgaaggtcg
    37681 caacttttca gtattttaca ttatacgtca tatttctgaa aatttcatcc cttaattatc
    37741 aagtcgtaaa aatactgttc tactggacct attcagtaca caaacatgat agtcaaccaa
    37801 aaaatcactc atcttttgag cattcgatat aaaaaattgg catactcata aaaagggcca
    37861 gcctttcggc aataaggaat aattttataa attgtgaaaa actatttttc aaaattgctt
    37921 cttatcgctt aaagctgcac gtctcattta caaccttttc tttttagatg ttatgagttg
    37981 ctcagataag tgattttgtt tactctaaga aaaaagggag gcaaaagata catgaattac
    38041 tttatcagtg atatgcactt tttccatgaa cgcttattag gaaaaaacga ctttgctccg
    38101 cggctctttg caaatgtgga tgaaatgaac caacagttga tcactagctg gaatgcagta
    38161 ataaaagaaa ccgaccatgt ttatcatcta ggcgaccttg ctatgcatcc gcaatatgaa
    38221 aaagcaaatg cagaaatttt ggaactggtc actcaactgc aaggaacaat ccacttgatc
    38281 aaagggaacc atgacagtcg cgcttttttc cgttatttag aaaaaaatga tcctaggctt
    38341 actgacggaa gtcccaaatt ttatttttat gatgtaggtg ccatcgttaa attcgaccat
    38401 caacaatatt acttgactca ttatccgatg ttgctcgggc ctaacgacac tatccgcaat
    38461 cttcatggac atatccatca ttacagcgta cctatcgaga acgatgtcaa tgtaggcgta
    38521 gacgcaccgg aaagagaact cttaaaggaa aaactaccat ttggcactcc gttatctgag
    38581 caacaaatca aagaaatcta tgaagcaaag aggaagtacg ataggtcgtg aaaaaactgc
    38641 cctatatcaa gtattaaaca aataaagata attactcata tttttcattt gagtaggctt
    38701 attgccacag gaacattagg atcagaaatg gagttgtaac aagacttctg tcacaactcc
    38761 attccatact attcgtcttt ttgctcatgg tgttctttta ccagtttttt ctgtaattct
    38821 ttatcataat ttcgggcagc tgacgttaaa aataaaacga ttccgcataa taaaatcccg
    38881 attccggaaa acaagaacat tttttctacc cctaaacgat cagctaatgg tcctgcaaat
    38941 aataatccaa ttggacctgc caggttcatc aaagagttga agttccctaa gacacgacct
    39001 aaaacattcg attcataact ctgctggatc attgccatca gcagtgtatt gaaatatggc
    39061 gttgcacaac ctgctcctgc attcaagata agaaagtaca agaacccttg actatcgttt
    39121 ggaaccaatc cgcttgcacc gatcgtcagg cccataatga tgtaggctat aataataggt
    39181 ttcattcggt ctttccatgt tcctataaaa ctgatcagtg caccgcctaa gagcattccg
    39241 actgcgtaga ctacttccac tgctcccgcc tgtccaacgg aaccaccaaa gtaatctagc
    39301 gtcatcaatg gatacagact gattgctggc atgaacaaca gcatcacaaa tgcaccattg
    39361 atcgttatgt accataaccc tttattatcc atcaattgct gcagcccaaa ttttgcatct
    39421 ttaaaaatag taagcggaac ttccaatatt tcaggagaaa cttttgggat cttcacaaaa
    39481 atcaataagc cgacaccaaa aactgccccc aatacatcta ataaaataag gtaattgaca
    39541 ggaacgactg aaaacaaagc cgcacctaga gctggcgcaa tgatgaaatt cgctgattgg
    39601 accattccta actgtccatt cgtccttgtt atgtgagaag atggaacgat tgtcggcata
    39661 atcgactgga tcgttggcat ttggaatgtt tgtgcgaccg aacgcataaa caaagacaca
    39721 aaaactagcc aaatcgggaa ggattctgaa atcgttccga ctactgctaa aataagcgcg
    39781 aaaatcgcta caataatatc cgtgacaatc aaaagagctt ttttatccca gcgatccact
    39841 agcggtccta caaatgggct tagtaaaacc atgggaatca ttcctagtaa agtagcaaaa
    39901 ctcaaaattg tcgccgaacc ggtttctctt gtcaaatacc agatgatcgc atattggacg
    39961 accatactag tgattcctga caaaaactgt cccgataaaa agaacaaata atttctcttc
    40021 caattcgtta aaacgaccga ctgttcattt tccataaaca tccctctttt ctttttcatt
    40081 ttgtatagcg tttgcacaac aatcattata cgggattctt ttttcaaaaa ataccttttt
    40141 ccctaaataa caatcgtttc aatttaaatt tctttactta gaaacaataa atcagcaaaa
    40201 tattaaaaat aacaacatgt gttaaattta aaaataaaaa agacaactaa tttgcgtcgt
    40261 ccttacaaag ttagtcatct aacaataggc cgtttcaaaa ctagttgtct ttttatatcc
    40321 acagatcatt cgactttttc gaataaccca cggctaatca tcccatccat cagaaaataa
    40381 aatttatctt ggctcatttt ctgttttgga tctttgaaaa tattgactgc tttcaatcca
    40441 tttgctgtag tgatcgacat tttcaatgtt tgaatatctt ttgatacagt gatttttaat
    40501 ttgaatcctt ctttgctttg cggcgtggca tctaatggtc ggatcaattg ataattgcct
    40561 ccgtttgttt ctgtaaatcc attatcgcgc aatgtatatc tttttgcatc aggatgcaaa
    40621 cgatagctaa ttggtgcgcc cagtaccgtt gctgttgttt caaatgccat gattttcacc
    40681 tcgataaaat tagtttctct ttattataaa agtttatcct gatttttact aggtttttca
    40741 gttaagttcc ctaaaaaatg aaggcgttct ctcagacatc tgttcatata agaatgactt
    40801 cactagttat tttttgacag cacgaactaa ttgatcaagg aaatactgga tgtcgtcttc
    40861 ggtatttccc aaaccaaagc tgatacggat ggattctttt agtatcggtg tatcttctcc
    40921 atacattgct tctaatacgt gtgaaggctc gatatttcct gctgtacaag ctgaaccagt
    40981 agaaatagcg accccattaa gatcaagctt catcagtagc aaatcatttg cttcgccaat
    41041 taagcgaaga ttcaacacat gagggagttt attcgttaaa tcaccattta cttgataagg
    41101 gatttcgttt gcttctaatg tatcaagaat caattgctgg aatcctttat atttgttgtt
    41161 acgtgcttca cgttcttcag gtgacagcag ttcaactgct tttgccatac cccagatccc
    41221 tgctaaattt tctgtacctg cacgccgctt ttcttcctgc tccccgccta aaagcaatgc
    41281 agggatattt actccgtctc gtttatataa gaaaccgacg ccttttggcc cattgatttt
    41341 atgagcagag atacttaata aatcgattcc taattcttct ggatggatcg tttggtttcc
    41401 gtacgcttgt accgcatctg tatggaaata agctggatga tccgctaaaa gttcaccgat
    41461 ttctttgatt ggcatcaaat ttccgatttc attgttcccg tacatcacag agaccaagat
    41521 cgtatcttct cgtaacgctt ttttgacctc ttcgatcgac agattccctt tttcatctac
    41581 aggcagatat gtaacgtcaa acccctttgt ctctaaatat ttcatggtat taagaacagc
    41641 aggatgttcg atagctgtag tgattagatg tctgccttct ttttgacgcg agaacgctgt
    41701 ttctaagata gctgtattat ccccttctgt tcccccactg ttaaagatga tctcgtgagg
    41761 ttttgcttgc agactgtctg caatgatttg tcttgctgtt tccaattttt catgcgcgtg
    41821 gcgaccaaat ccatgtatgc ttgaaggatt tccaaacgtg tcttgcatga ttgccgtcat
    41881 cgcttcaatt acttgtggat gcatgggggt agttgccgca tgatccagat aaatagtttt
    41941 cacttcattc atcccttcca aattattgct aggcacattc tagcataaaa tagcgaacaa
    42001 accaaagaag agctcatttt tgtctagagg acgtttcatg ggcatagaaa aaaggagctg
    42061 tgacaaaagt cttgtcgcag ctccttgaag ctgctcactt ctgtcacaac ttctttccct
    42121 cttttttttg tttattcgaa ttctttttct tccagacgga ataacggact catcggtgta
    42181 ttttcatgga tgcgtttgac cgcttcaccc attaattctg aacatgtaac gattgttaag
    42241 ttttctggat gacgattttc ttctgtgaaa acagaatcag tgatacaaat atctttgatt
    42301 ggtgcattgt ctaaaatact tttcgcatga tcggacaata atccatgtga cgcacaggca
    42361 tatacttctt ttgcgccgtt ttcttttaat acatttgctg ctcgtgcaag cgttgctcct
    42421 gtgttcaaga tatcatctac catgatacat gtctttcctt gaacatcacc gatcacataa
    42481 ccaccctcag ttgaagcatc atctgcatga tctacgatgg ctaatgtgct gttcaaatat
    42541 tctgaaagac tacgtgcacg ctgaacaccg ctgttttttg gcgaaacaac tacgatgtca
    42601 tctcccgtca gacctaattg acggtaataa tgagcaaaca acggcatcgt aaataaatta
    42661 tctacaggaa tatcaaagaa tccttgtact tgaaccgtgt gcagatctaa agtcagtact
    42721 cgagttgccc ctgcttcttc gatcaagtta gcgatcaatt tcgcagtgat cggttcatga
    42781 ggtttcgccg tgcggtcttg cctagcatac ccatagtaag gcaatacgac attgatcgtt
    42841 ttcgcacttg ctcgcttcat tgcatcgatc atgatcagta gttccatata gtaatcattg
    42901 acaggtgcat tcgttgattg aacgatatac acatgatccc ctcgaatact ttcttcgata
    42961 ttgatggaaa tctcgccatc actaaattgc ttcacgacgc ttttacctaa ttctgttccg
    43021 aacactttcg cgattttttc agctaatgga cggttgccat tcaaactaaa aatcttcaac
    43081 gtgtcatcct gatacttatt actcatgtag tcctccccaa aacttctcta ttcttcgata
    43141 gtttaacata tttttccaag attttctgtt aatttcagca aattcttaag gaagtgaaac
    43201 tgttccgtta ctccaactgg caggaatgac tttatgataa tcgccccagt tgtcgtgtac
    43261 tttgtaataa cgttctcctg tttcagtttc aaaataagcg tacgctgtca cccaatgatt
    43321 gccatatgta ctgccaagta ctttcaaaat accaatcatc acaggtttgc cttcacgtat
    43381 acgttttgta gctcgctgcc atgaacctag aagagttgct cgtgcacgct catgattgcc
    43441 attcttcttt aaaaaactag aaatccctgt actaacctga aaaggaatcg taggaagtcc
    43501 tagtggttgg atctggctac gcaatgcctt cgtcaaaacc aacgaatcag ccgtattttt
    43561 cttgcgaatc tcatttggaa gcatccaccc cttacgatag tcttgataat aggcaaggag
    43621 aactgctgcc gcgtaagtac cacaaagata gcctgagggg gtagcccatt tcttatacct
    43681 caaaaaacgt tcttctggca atcccaccca gcaatttgcg agttcctttc ctgacctttt
    43741 ttcttcgatc aaaacgggaa tatcttcttt tctgttgatc catctagata actcgattgg
    43801 ctcttcattg atcagcttcc attttttaca agaaagaccc tcttgataag tatattttgc
    43861 tggagaatat tctaccggat gtcctgattg atcgataatc acataacttt gatcttcaaa
    43921 aaccagagct aaaaaaagca atttactttt tcttgactgc agctgctgag tgctggctaa
    43981 ttttttaatt tttttatcta ctttgaaata taaaggttta tccactactt gattcagttg
    44041 ggatcgcctc ctttttttca ttataagtga aggattgaaa aaaacaaatc agtttgattg
    44101 ttcgaatttt caatttttta tgttctattt gttaattcct tcattttgta agataatggg
    44161 cacacgaaac aaaaaaggag cgatcgatga atgaacaaag aacgattgaa acaagatttc
    44221 tatgaagcag tcaatgaaga atggcaaaaa acagcaaaaa tccctgcaga taaaccagct
    44281 acaggcggtt tccaagattt agttgacggg atcgaccaac ttttgatggg agaaacagac
    44341 gatctgcttg cccatccaga aaaagtgtct tcagaaaaaa tgaaacattt ccttgcatat
    44401 tatcaactgg caaacgatta tgaccgaaga aatgagttgc atgctcaacc gcttcaacct
    44461 ataatcgaaa aagttgaatc attgcagtct ttcgacgaat tgaataagca atttccagaa
    44521 tggctgttgg atacattacc attgccattt aatctggatg tagatgcaga tatgaagaat
    44581 gcgcaaacga acgccttctt tgcttatccg ccttctttat tccttccaga taagacgtat
    44641 tatgcatcag accatcccaa cggtgcacaa ctaataggcg ttttctttga tatggctgtt
    44701 cagttattag agcttgccgg caaagaaaaa agtcaggcag aagcaatcac ggaacaagca
    44761 gtgcaatttg ataaattgat tgctcctcat gtaaaaagtg cagaagaaaa cgcagattac
    44821 agcaaaatgt ataatccgca atcttttgat acatttatta aatacacaga taaactggac
    44881 ttgaaaaaac ttgtcacggg tttgattggg acaactccag ataaagtgat cgtaactgat
    44941 ccagtgtact tcgatcattt gaatgacatc ctgacagaag ctcattttcc gttattcaaa
    45001 agctggatga tcattaaaac agtacgttct cttagtggtt atctatcaga agaattccgc
    45061 caagtcagcg gaatctattc tcgcgtattg tctggaacag acgaagcaat gcctcagaaa
    45121 aaagcagcgt attaccttgc ctctggacaa ttcgatcaag tagttggcga ttactacgga
    45181 aaaaaatatt ttggcgaagc tgctaaaaaa gacgtagaac aaatggtgaa aaaaatgatc
    45241 gccgtttata aaaaacgtct agaagaaaat gactggcttg gggatgcaac aaaagaaaaa
    45301 gccgtcataa aattaaataa cttaggtatc caagtaggct accccgataa gatcccagca
    45361 ttattcgacc agttcaaaac agtacctgca gatcagggtg gtactttgct ttcaaatact
    45421 cttgttttca gcaaactcac attaaaagat cgtttcagca aatggaacaa accagtggat
    45481 cgttcagaat gggaaatgag tgctgacacg gtcaatgctt attatcatcc atttcggaat
    45541 gtgatcgtct ttccggcagc gatccttcaa gcaccatttt acagtctaga acaatcaagc
    45601 tctgctaatt atggtggaat cggagctgtt atcgctcatg agatttccca tgcatttgat
    45661 aataacggcg ctttatttga cgaatatggc aacttgaaca actggtggac agaagaagat
    45721 cttacacaat ttcaaaacaa agcacaagca atgatcgaag aattcgatgg tctgcctttt
    45781 gctgacggaa aagtaaacgg aaaattaacc gtttcggaaa atattgctga tgcaggcggt
    45841 ctaagctgtg cattggaagc agcaaaaacg gaatcagatc tttctatcga ggaattcttt
    45901 gtcaattggg caacgatttg gcgtacaaaa gcaaaaaaag aataccaaca acttttactg
    45961 caaatcgatg tccatgcccc tgctaaactc cgagcaaacg tgcaaccaaa aaaccttgac
    46021 gaattctatg aaacatttgg tatcacggaa caagacgcta tgtatctagc gccagaaaaa
    46081 agagtgcgaa tctggtaaga ggttgtgcca gaagtggtca gcttcaagaa ataagaagga
    46141 atttgggaaa atcgcttctc aaatttttgt gacatttcgg cttatttttc gaagaagtta
    46201 cttctggaat accatgtatt agaggttgtg aaaaagctgc ttagtttcaa gtagtaagaa
    46261 aaattttgtg aaaatggctt tccacatttt tgcataaatt tgacttacta ccgagaaact
    46321 ggcttttgaa caccgtttat cgagaggttg tgaaatcagc gtcctgacct gagtattaga
    46381 gaaaaaaacg gaaaaatagt tcctcatatt ttgccgtttg ttgagctaat accgagggtc
    46441 agctgattga acaccgttta gtggagagat tgtgaaaaag ctgtcctgca tcaagtaata
    46501 agaacagcca atcaaaagca gcaaggagaa cctcatctat aaaaagatag aaggaagtga
    46561 gacatctatt ggtctcattt ccttctattt ttactttcct cagtcaattg ttttacatca
    46621 taaaaggaga aattccactt atttttttcg ctgtttcatg acataaacaa ctacaccgat
    46681 taacaaaatt cctccagcta atgctagcaa cgggttatta aattctcccg tttttgggag
    46741 tccttgagtg ccattttttt cactttcttt tgctgtccta tccggatgag aaggttttcc
    46801 atttggtttt ccatttggtg attcatttcc tggattttct ctttctggtt tgtcatttcc
    46861 cgggggcaca tcggcagttt ctcgcacagt gatcgctttt tgctgggtaa cagattctgt
    46921 atgagcagac catttttccc catcaaatat ttccgaacga taagtgactt ctagcgtata
    46981 ttctcctttt gaaggtgctg aaaaaatagc ggtatgatta gaaaattgag cacttgactg
    47041 tgtttcaacg atttggatct tttctgggaa ataacgcata tcttcaaaga caggcgttcc
    47101 ttgatttggt gtgaaagttg acacaaaaac tgtaaaaggc ttcagttcaa tgatatttcc
    47161 ttctgcattc tccgccacac catttgcttc ttgtataata atcggattat tttgttcatt
    47221 tggttttgtc tgatttggtt cttgtacgat tgcatactct ggatattccg aagacggtga
    47281 ggtttctccg tcaaaaatag cacctacaga taatggaaga ccatccactc tttccttttc
    47341 tgtttgacga ttccccggtt taatctgcat cagtccatga acatggatac ttccattttc
    47401 atagcgcgta acaggctgct gaccttcttt cgaacatgta tttagagact cgatccaatc
    47461 ttttgatatg gtatgtccaa gagtattttc tgattgtttc tctcgttcat tccaatagta
    47521 gttcaacgag tggtagattt gatcttcgtt ttgattcaat gggcggatct gctctctcat
    47581 ctcaagattc tctgttcgga aagataagat accagaagca tggtagtctg tgtttcctgc
    47641 tgaagaggta taaagagcca cattatatga accgttatta aaacttgtac tgctattgac
    47701 gataatatct gttccgctat tggaatcgat tcctttcgca agattttcga aagacaaact
    47761 attgatcaat tcatgagggc ccgttaaaga agaaccgccc attttgaatc cattaccgtt
    47821 accttctccc tcaattcctg gtacccagcc gtttcgataa gcaactgagt ttttgatgat
    47881 tacttttccg atcgaacctg tttcattttt agcaaaaagg tcccaaccgt catctgcatt
    47941 atgatacgcg atacaaccgt caaatacatt tccttctcct attgtcagtt tggccgcaaa
    48001 tccatcggca tcttcaaatc ctggatcggc attttcaaaa gatgtacagt tcttgactaa
    48061 gttatgcgcg ggccatgctt cgaaaggatc atttgagcta ccgctgattt ggattcctgt
    48121 atttccattc cgataagcat gaatctcttc gatcaaatta tgatttccag aaatctgtaa
    48181 tcctttttgc atagctgcac tatttgtaat gtcaaaccct cgtaaacccc agtagtgact
    48241 gaacagtgtc atcccatttc cagttccttt aaaatcaagt acaggacgct tgttttctgg
    48301 atttttctct gcaatcaact gaatcgggtt ttctcttgtc ccgttaacgc cttttggaat
    48361 cgtcaatcct ctttcgaagg aataagttcc aggcgccatg acgattgtct gcccagcata
    48421 tgcgtatctc aatgcttgtg tcagagataa tggattttgt ctgcttccgt ttcctgcatc
    48481 tgacccttct ggtgttacat aaactgtcga atatttaggt ttacggtagt ccactgtatg
    48541 aagaatctct tttgtttcat aactagtcat ctctacgtat tcttctggcg gatagttttt
    48601 atctggcgta aaactgaaag taaattcgtt cgttccttcc atcagttttg tctgataatc
    48661 aaattcccga ttcgcagtga tagccaagtt ttttgcgttc ttaagcacct ctcctgttgc
    48721 tttattttta attgtcaata atccgtcagc atttgctcta aaggacatag tatgatcttg
    48781 gtttcctgaa tgattactag aggtcacagt gtaaatcgga tcaatcaagc gagtaggtct
    48841 ttcttgccca ggaggatctg tcgcaggatc tgagtaagca acttcgattc cttctacctt
    48901 gatcgtcata ttccttgctg cagcaaatcc tgcataaata accgattcat ctgaagcgta
    48961 taatttttcc cagtcataca tgatgtcaga agccatttct tctcctgttt caggatcgta
    49021 ataatatgcc tctaaaccag tattcgtttt tttcatctct acgtccagtt tagtaatcga
    49081 gttcgtggcc ggaaacagat tcccatgacc gtttccgaat atattataag aacctgtttc
    49141 tttttccaag aaccctgctg aagtctctaa aggtgttgtt tccactgaga cactcccagg
    49201 agctggcgca gcttgcggat cttcagatga tattcctgtg attgcccgtg tccccaatcc
    49261 aagtcgcatc gtatatttgc tgccgctcgt gttgaccact tcttgtctat ccgagtccca
    49321 gacatattcg atccgactgc ctagtatggc aaatgaattt gaataaaatg cctgcccaaa
    49381 caaatgattt tttggtactg cgtctcttac cattaaagca aatccttctt gggcattcgt
    49441 ataggtccaa gattctattt cgatcgtcgc ccgcatccta aagttgatgt ctttggggat
    49501 tgcttgataa taataggtca ttccatctga tccgcttgac tggaattttc cgccgttatt
    49561 cgtggaagag agccgcacgc cgtcttctaa tggttcaatg gcatacctac tagcacttgt
    49621 gctttctccg aaaacaaccc ctttccactc ttcatttgct tcttcagatt gcttttttgt
    49681 cttttcattt tctgattctt tcatcatagg atcatttcct tcttccgtat ccatatcttc
    49741 actagttctt ggtatttcct ccattgttga catcccttca atgttcacgt gtgcattttc
    49801 ttcgttcaca gactgttgtt cgttagcagc aacttcaacg acagaaatta aaaccggggt
    49861 actgagcata aggagattca tcattagcgc actgtatttt atacgttttt ttaacaagtg
    49921 tattcctccc gtaacaaatt agaaagcgtt tacttaaagt attacctaat ttatttttac
    49981 tgtcaataaa aaacaaaatt ataataagtg tattttataa aaagaaaaaa tataacttaa
    50041 gttgttgata ataaagagat ttattaacgg aaaaagaata agttttttta aaataacgta
    50101 taaaaaagag cataaaacaa agtcgtttgt tttatgctct tcttttatta ttttgtgctt
    50161 tttattttat caaatcactt tgttttttta taaaatttct gcgcctagtg tggactcaaa
    50221 atgtctcaat gcccattcat gtccaacggg atcgaaactt gccacggaat ctttgaaaat
    50281 atggagtttg tatcctagat tatacgcatc gactgctgta tgcaacacac agatatctgt
    50341 acatacgccg gtcaaataaa tatctgtgat ctggcgttct cgcaaacgga tgtctagatc
    50401 tgttccacta aaagcggaat aatgccgttt gtctatccaa taaacatttt cctcttgctc
    50461 atagtcttgg tataaacttt ttaaagagcc gtacaattcc cgtccacccg ttcctatcac
    50521 attatgcgga ggaaataagc ggttctccgg atgaaaggaa tcttttggat catgcgcatc
    50581 aatggcaaaa acgacaaaat ccttttgatc aataaacttc tttgtatgag cagtcagctt
    50641 tttttcaatt acttgtcctg ctgtcccagt agtcagcttt ccatcctctg caacaaaatc
    50701 atatgtgtag tcaatcgaga tcaatgcgtt catcttagtc ctccttatac gagatgtttg
    50761 acaaattcga tcaccatttc tgctgatcgt ttgcctgcgt cttcgataaa ttcgtcaaag
    50821 ctttgtgtcg ccgagtgatc tgctgtgtcg ctcattgcac gtacgatcaa aaatgggata
    50881 ttgaactgac gagctgtttg tccaacagcg gctccttcca tttcgcaagc taatgcttca
    50941 gggaaattcg ttaagatttc tttgatttta tctggcgagt cgacaaatgt atcacctgta
    51001 acgatcaatc cttcttttgc gttcaaattc gttgcttttg ctgctttaac catttcactg
    51061 cgcaaatatg tgcttgcttc ataatataga ggcattcctg gtaattgtcc tgggttgtag
    51121 ccaaatcctg ttgcatctgc atcaaaataa gctactttgt ctgatataac gatgtcacct
    51181 acttgtaagc cttcaccgat tccgccagct gaacctgtat tgatcaccat gttcacgccg
    51241 tattgttgga tcaacagact tgtggtaata gatgctaaga cttttcctat accggaacgt
    51301 acgacgatca cttcgtggtt acctaatgaa cctgaaataa ataaagcgcc tgcgcgttcc
    51361 catgataatg gttcgcttag gttctctctc aaaattttta cttcttcttc cattgcgccg
    51421 ataataccga ttttcatctt tttaattcct tctttctata taaatgcgat tgctaaaaaa
    51481 accacacata acattaggat aacaataata agagatttca tcaaaaaaga gttccatttg
    51541 gtcgtctttt cccgttcgct gatccttgtt ttcgtgattg gtttattctt tttgctttct
    51601 ttacgataaa agctggcaat ctttttttct tcttgctgat aagctgtttc tgcttttcgc
    51661 tgttttttta atgactcgct tgcttgtgct tgttgtcgct tgcgaagttc gcttcgcgta
    51721 ataagcggtc ctttggccat aagccgatcc ctctactttc ctttggtcaa tagttcccag
    51781 tattgaatcg cataaatcgt ctttgcatca caaatcaact gatctttcat cgcttgttgc
    51841 gcctcttcaa gagttagatg atacaactcc agtacttcgt cttcatcttg tgctaaagga
    51901 ttctcgacct tctctacccc ttgtgcatga taaatatgaa ggacttcatt tgcaaaacct
    51961 ggtgaaagat acatcgaagt aagatggctc agcgacttcg cacgatagcc agtttcttct
    52021 tctaattctc tagctgctgt catttcggga ttttgtcctt ctcctggatc gatttttcca
    52081 gctggaatct ccaaaatcac tttttctaaa ggttttcgaa attgtttgac aagaagcaga
    52141 cgatcttgtt cgtcaaaagc aatgatcccg acaccgccag gatgaaatac cagttctctc
    52201 ttcgaagttc ctccatctgg caaacgaact tcgtctacag caacatcaat aatttttccg
    52261 ctatagattt ctttgcgact gattgttttt tcttcaaatt gctcattgtt cagcatatct
    52321 tctcctgctt tctttgtaat cataactgct tttttttcat ttttcaattt ttctcaaaaa
    52381 ctccttatta gtttaccata gataaacctt agattttctc taaatataga aaatccttct
    52441 ttagtccgat actctttcta gtagtccgta tgctaaaata agtatgtaat cgaataacga
    52501 aaagaattca atactcaacg ataaatgaca tggagggttt attatgataa aacgaaattg
    52561 gccgtggctt ctagcattgg tcttgctatt tctctttgtc cgaaacaata gtttttcttt
    52621 tgttctagga cttttattga taggtgtagt tttagttttg tggggactct ttggttcgcg
    52681 caggaaaaag ggaaaacaag aagaaattcc tgcactgact gacgaacttg aaactcacta
    52741 tgaaaaaagc ggtatgacag cgaatgaaat ttcatttttt cgacaaacaa tgaatcaaac
    52801 aaaaaatgag atcaatcaat tgcaaatgaa tatgcagcag acagccaaac ttaaagcaat
    52861 cgatctccgc catgatccag tcaaagcagc gaaagcttta ttcaaagaat tggtgaaaga
    52921 accaaaccga ctgcatgaag caagtcagtt tctttatacg catctgccga atctagttga
    52981 tttgacaaat aagtataatg agatcaatga ccatgagatc aaaaacaaac agacctatga
    53041 aaaactagaa gaaagcgcgc agatcatcga ccagctgtca gctttaatcg cacaagatta
    53101 tcaaaaattc gttgctgagg atctagatga tatcgacgta gagatatctg ttgcgaaaca
    53161 gagcttaaag cgtgataata aatatgaacc agaacaaaag gattaactct tttgttcata
    53221 aaagaagact cggaacattc agatgatgtc tggctgtttc gagtactttt tctaaagtag
    53281 agacattcat gtaagaatcg agaacagatt caacaaggag gaatttttta tggatcataa
    53341 accgactgaa acaaaagatg ttacaccagt taacgataca cttgaagatt tattgaacaa
    53401 cccgttttca actccaacag atacgctgac cacttcacaa caagcggaga ttgatcagct
    53461 ccaagagcaa cagacagctg ctcgtttaat tgacaaacta ccggcggaac gccaagaaca
    53521 agctaaacag ctagcagcaa aaatcgatgc taatgatgca cagtctgtca tcagctacgg
    53581 atcggctgcc caagcaaaat taagtgaatt ctcacaatcg atgttgaatc atgtgcaagc
    53641 acaagatatt ggtcctgtag gagattcctt aactgaactg atgtatcgtc tccaagaagc
    53701 caatcctgac gaactgcgtg ccggagaagg gaacatcttc cagcgtgtct tcgggaaggt
    53761 caaacaatcg atctatgaag tgacagcaaa atatcaaaag attggtgcac aaattgacaa
    53821 gatttcagtg aaattagata aagaaaaaga cggtctgcta aaagataatc tgatgttaga
    53881 acagctttac cagaaaaaca aagactactt tgatgcactg aatatttata tcgctgctgg
    53941 agaattgaaa atggaagaac ttcaaacaac gatcattcca gaagcgatga aaagagcaga
    54001 agaaactggc gatcagatgg atgttcagat tgccaatgat tacacgcaat tcctagatcg
    54061 tctggataaa cgtacgcatg atcttcgctt agctagacag atcacgatcc agcaagcacc
    54121 acaaatccgt ttgatccaaa acacaaatca ggccttggct gaaaagatcc aagcatctat
    54181 cgctacagcc attccgctgt ggaaaaacca agtcgtgatc gcattgacct tgcttcgtca
    54241 aaaagatgca gtaactgctc aacgccaagt ctctgaaaca acaaacgact tattgaagaa
    54301 aaattcagaa atgctgaaaa tctcagccat cgaaacagcg aaagaaaatg aacgtggaat
    54361 cgtggatatc gagacccttc aaaccactca aaatgatttg atcgaaacaa tccaagagac
    54421 attgcgtatc caaaaagaag gaaaagaaaa acgtcgtcat gcagaagtag agcttggaca
    54481 catggaagaa gatctgaaac aaaaactgtt ggatttaacc caatagatca cctttcgctt
    54541 gttactaaaa caaacgccca acaacagttt attacaactg ttgatgggcg tttttcttat
    54601 ctttcttcta acttctccat tggagtctat ttctcattca tcttgctgtg tccatagcca
    54661 tagccaaaat aaatgatcag tccaataacc attacgatac cgaacacgat ccatgtcaca
    54721 gtttgcagac gaagcatcaa tacaatacaa gtcaagatgg agacgattgg caatagcgga
    54781 acgaatggca ctttgaattc tccagctttt ggtttgccaa acatttttct caacttcagt
    54841 aagcctagac taacaagcat caaataggcg agcgccatga tattcgttag ttccgctaat
    54901 acattcaatg ggaaaaatcc ggcaaagaat acagctgcca caccagcggc ataagtcgct
    54961 tttttcggtg tacgatgctt ttgatcgatt tctgtcataa acttaggaag taagccatcc
    55021 ttgctgacag caaacagtaa acgagcaagt gaatacatca tcgagatcgt taccgtcagt
    55081 agcgttaaaa ttgcccctac agcgatcacc gcgcccactg ttccatgtcc tacatacctc
    55141 attgcaaaag ccactgggtc attgactcct agttcagtat acggaacgat tcctgtcaag
    55201 atcagcgtca cgatgatgta aaggacagta gcaatcagta tcgaaccaat gattcctctt
    55261 ggcacatctt tttgcgggtt tttgacttcc tcggctgcca ttgcaacggc atcaaatccc
    55321 aagaaagcaa aaaacacaag agctgcacca tctagcacac cggaaaaacc aaaaggcatg
    55381 aatggctgcc agttatcagg tttaacgaaa aatattccta caatgataaa caacgcgatg
    55441 ataccaaatt tgacatatac catggcatta ttcaaacgta atgctttctt ggcttcaagc
    55501 gacacgatgt aagtgacgaa tatcactacg agcaccgcaa tcaagtcaat gtatgtacca
    55561 ttttccggat tgtacccgcc agttaatgct tgtggaagtt cggcccctaa acttttcaaa
    55621 aaaccttgca tatagccaga ccatccggaa gcaacagagg aaaccgctag taaaaattcc
    55681 ccgatcaaca accaccctgt cagccaggca gcaaattcac caaatacaac atacagatag
    55741 gcatatggcc caccaatcac tggcactcgc gaagcaaatt ctgcgaaact tagtccagac
    55801 aaaatgacaa cgattgcagc taagacaaat gaaagtgaca gtgctggacc agcattttga
    55861 ttggccgcaa cccctgtcac cacaaatatt cccgtaccga tgatcgcacc aattccaagc
    55921 atgatcaaat cagacgtttt tagttctttt ttcatctcac tcgtatgatt gagattgatc
    55981 tctttcttac gaaacaaatc cattgaagtt cctccccatt ttaggttgga aaacagcgat
    56041 taaactgttt tcatataccc taaaaggata ccacctaaaa tgactaaaag gcaaccaaca
    56101 ataacataaa tgagctcttt tttcgttttt ctttcgccaa ggatgaaaat cccacctaaa
    56161 gtagagataa tgatccccat ttgtgaaagt gagaagccaa cagctaaacc aagtgatttg
    56221 actgttagaa gcatgcagat gtttcctaag ccccataata atccacagat catgtttttc
    56281 cacacaaact gatcgacttt aactttacgg aaagcaaaga agcttgcgcc taagatcatt
    56341 ccgatacttt gaggtaagat aattgacatc gcatccaaat tcgcccagtt gacgatgatg
    56401 gtatatacac cataaccaat cgtagagaag atcaatgctc taaaaccctt accaaaatca
    56461 agcattttat tatctgtatc tatttttcct tcgtcatctt gtcgggcagt caaatacgca
    56521 ccgcttacaa gaagagctaa agcaataata ccgtatacat aatctttcgt ttgtgtccat
    56581 tcatggaaga aaacggctcc cgcaatcgta ttcaaaatta attgaaaacc agtagacaat
    56641 ggtagcccta cagaaacacc catgtacttc attccatgga actgtccatt ttgtccaaca
    56701 ctccaagcta agccggataa aaatccgatc aagaaaatcc aaggggtgat tacaggacta
    56761 acaacgaaaa agacaactaa agaaaacaga aatgcaccga tcgtcattcc tagtgtttgt
    56821 tgattggcat cgccaccaat tttaccactt actaaaccaa tactacccca tgccaacata
    56881 gggactaatg ctattaaaat ttccataacc aatctccttt tatttcacat gataagaaac
    56941 ttatcagcga aaacgttaac aacacaagca ctttttttcg tttctaacga ttttctaacg
    57001 tttttcatta taaaaattta agattgggaa aaataaagtc attgttgtcc cttttccttc
    57061 agttgattca gccgtcaaat ggatacctaa tttttcggcc agattttttg ctaaataaag
    57121 tcctaatcct gttgaatgtg ttttgctaag tcgaccattt ctcccagtaa atcccttatc
    57181 aaagatccgt ttcaagtctt ccgctgggat accgatccct gaatctttaa ctgaaaggct
    57241 gactccttgc gcttcctttt ctatgctcac aatgatgttt ccgtgatccg gcgtatattt
    57301 gatggcatta ctaagcaatt ggttgaagat aaaagcgatc catttagcat cggtcaaaac
    57361 agtatgatcc tcaccaacga tctcgtagcg aatatttttt tggataaaat aatttgcctg
    57421 actgcgtatc acaggctgaa tgattccttt tagtccatat tcttggatga ggtagtcccg
    57481 cgagaaactg tcgagtcttg cataatacaa aacttgttct acgtattcat cgatttttga
    57541 taattcattt tctagtaatg tatacttttg atcgtcaata tcgaactcga tcgaacgaac
    57601 tagcaattta gaagcggaaa gtggcacttt gatttcatgg acccatgagt caatataatc
    57661 tttttggtct tgttgattac tgattgctga ttgcattact tcttggtgtt cacggatcag
    57721 ctgattgata tattcttcta ccagtttttc ttcttctgtc ctcccaccac tcaaataatt
    57781 ttgcaaaggg gaagtttttt gtatgtcggc taattttccc caccatcttc tcttgctcaa
    57841 gtaaccaccc agcagataaa aaatcagaaa gacgccctca atcaaagcta aataagcaat
    57901 tgtgctcaaa tcaactttga tgtttggcgc cagccacatc acaaagatcg tcaatgcaat
    57961 aaaaaacagc catcccaaga tcaatgtcca ctgatctttc aaatatttaa aaaaattcat
    58021 cttaaccgct catcctttca gggaacgata tatccctgtc ctacttttgt ttcgatatat
    58081 ccttggatac ctgcctgttc gatttttcgg cgtaaccgat tgatgttgac tgtcaatgta
    58141 ttgtcatcta caaatcgttc gtcatcccac agtgctcgca gcaatttttc ccgacttaag
    58201 atctttccat tgtgcttcat caaaataaat aatagacgat attcattttt gctcaaatca
    58261 atgatctctc cgttgatttc catacttccg ttgtcaacat tcaacgtaat gccattgtgg
    58321 ctcatcattt cactagataa ttctgtgtag ttgtaagaac ggcgaagtaa tgcattgatt
    58381 tttgcaatca gtacatcgat ttggaaatgt tttgtcacaa aatcatctgc ccccatgttc
    58441 atagccatga tcatatccat attcgtattc ctgctggaga taaaaatgat cggtactttc
    58501 gatacttcac gtattttttg acaccaataa tagccatcca aaacgggaag attaatatct
    58561 agtaatacaa gctgtggttc ttctctttca aagtctgaga acacttgatt gaaatcggtc
    58621 gttccaaagg tttcaaattg ccatttctca agttcctcca tgatcaattg tcgaatgatc
    58681 tcttcgtctt cgactaccat gatttttgcc ataaaaaatc cctccatctt tcttcttgct
    58741 actacaatat caaagaagcc cttgtgaaac aagttggctt acctggaaaa tgtcatttta
    58801 gcaaacgtta aaaaaaactg gaaatatgcg atttaatcgc gtttgtctct tccaagcagc
    58861 ttaaatttat tatgttattc ttaataattg gtctattatc tgttattttt ctttcgttgt
    58921 ttttgtcttt taaattttcg ataacaccaa taaccgaaaa gcgttagcac tagcaatata
    58981 cctagaagga gtataagtaa tcgataaaga tggtattttt ttgtctgttc tatctttgaa
    59041 gagacttctt ctgtaaaggg aactcgtctt cctgtcacta gtaatcggtg agtgttcacg
    59101 gtgtaaggtg tacaagtgat aagtgtgact agatcctgct tttctctaat tgctaatgta
    59161 tttgtttttg ttggaaggac aacaattttc tcaacgactt cataagcgag catccgacca
    59221 tacacttcaa gatagaatcg gtcatcttgc tccatttctt caagatccgt aaagagtttt
    59281 ttctcagcaa taccgctatg ggcggtaatc acggaatgtg tactctctcc tccagttgga
    59341 aaagaggtgc cttgcaggac tgtcgctcct ctatctaaca aaagatcatt cgtttcatca
    59401 aataaaggca agctaacatt gattttcgga atatagatgg ctccgatcat atgttgttcg
    59461 taatattctt ttcctggatt ttggacattt ctaaccgctt gctcaaaagg atctttgact
    59521 tgtcccattc ctgggattac tgatgtatga gcaagcgtct gatttttctt ttcatgcact
    59581 gctaattgtt gctcatgttt ttcttcttta tcgcgttcaa gctgcttttg ataattctcg
    59641 atccttcttt gatccaaata attgctgaga gcatctgcta aaaatggata tgtaaaaact
    59701 gcagctccgg caagaaacat cactgccata aataattgta ataaaagact gatttgggtt
    59761 tgaggtctat tacctatttt ctttttcatt ttcttcacct tcttatttaa aaaaactgca
    59821 gcaaccttta taaaaccgat tgctgcagct tatttttgtt gcttatactt cagacttcat
    59881 tttagattta cggtaccagc tgtacgctcc aatcatcaaa cttattccga ttagtaagaa
    59941 tgccaagagc ccgttcccac cagtagcagg aagtgacccg cgtttcatat tcggtactct
    60001 ttctggccct ggattttcta ctcctacgat ctgaatttct tcattatagc ttccataaga
    60061 gatgataaat tcagtaaagg ctgcctcacc tgttggaagt acataacctt ctggcgccat
    60121 ggtctctttc atttgatagg ttccataatc taacccttga acctcaaagt atccatttcc
    60181 atctgcgaca aattctgttg cttgtccgct tgttgcccac tcaattctat ctgctcctga
    60241 ttcataaaca gctaaaggcg actccccttt ataaaatatt gcgtattcag aacggtcttc
    60301 attccacaat tcgaatcttg catctttaag caattcactg cttgatgcat catatttttc
    60361 aaactttctt ccacctgttg tgactttctc tggcggctct actccttctt cataatcaaa
    60421 ttcatcattt cgtccgattt caataaccgc tgtgttgtta tggaaatcat ccgcttctag
    60481 ttctgtggaa accttcaaat tatacgtgat cgttaaatct cctccacgtg catctgctaa
    60541 tctacctaaa gtatctactt tggctactcc attttcttct gtcaaaatcg tcacgacaaa
    60601 cccgttgctt actacttcta ctatataatc ttgtcctttt gttaaaatcg tctcgccggc
    60661 tcgcacttct atttcctgat cataataagt tagaccaact gtaggcgtat ctgtgatttt
    60721 gtaatttttg ataacagcgc ttccgttttc aaggacagaa tcgatgaaat aaggaatagg
    60781 tgctgtgatc gtgtaagaag ccgtttttcc tctttctaga tcaatataag aaatcgtttc
    60841 ttgttctcca gcttcattaa taatcgttac ttgtctaagg tcgctttcct ctacattcat
    60901 ctgtttatct gcttctctga tttcgttttt cggatacaaa tgcacatctg tattgtatgt
    60961 gtctttccat gtagaaccat cccacacgcc atccaccata tcaggcatca tcactggcat
    61021 cataacaacc attggagacg cgattctgga aatatgagct ggcgaataag tttctaagaa
    61081 aagatagact ttatctctag aagaaggtgc ttcttccgtc acttggacgg tagagaatac
    61141 cgcttctcca gcttcattcg ttgtttgttt gtcaatactt gtcagtcgat attttaaaaa
    61201 ccaactttct gtgtgccgtt tttgaatcca ttcaatcgct tcggcagaat taagaccgtc
    61261 ttctcgttcc ggtgttaaag gattatctcg aatcaaatcg taatatactt ccgttacgtc
    61321 aaacaaatca aaatcgactc ctggaatatt ttcttcacca aaatccgtag aaaccaatcc
    61381 gctattcggt cgttcttccg gaacagatga gaaacctttt ttgtgtaatg taatcgtcac
    61441 ttcacttggt ttttgtgcga cttcttcggc tttgactagt tttccgttcc cgaaaatccc
    61501 tattcccgca gtaacgagta acagtacact cattcccgtg acaatcattt ttttattcat
    61561 ttttttctcc ccgttctttt tttattaata aaacagcacc taacaataaa agaattccta
    61621 gtaaagaaat caacgttctt gcttcattcg tttgcgggaa tacggaccat tttcctgatt
    61681 gacctggatt gcttggacca ctcggctctt tcggtttgtc cgttgtttct tttacggtct
    61741 cgttataaac acgtggtgtt gcggattcat aggcagagac tggaactttc ccggattcta
    61801 attcagccat ctcctgtccg ttaactacta catattgtgg ttggcctttt gcatccaccc
    61861 aaaattcagg gatgatgacc tcgattctct tacttgcttc atccatctcg taaccttcca
    61921 caccttttaa ttcttcaaaa taataggtgc cagaaggcaa gaaacgttgt cctgtcgtaa
    61981 caaggccctc tttatccgaa atgaatttgc ttacattttt gtcattcaaa ggatcattgt
    62041 ctgctggttt gatccattga tttttcaagt cattagcagg agccatatct aaataatatt
    62101 tccccccttc tatcatctga tatagagcaa aaacagcacc ttctaatggt tttccttttt
    62161 cagttgttcc tctttgacgt ccatacttga agaagtatgg atctcttaga taaccgacat
    62221 ttttaggata gatatgaatc tcttgcagtt cctcggttga ttctgtcggg tgataaattg
    62281 gcaaaatagc agcaattggg atagctgtct gatcgatatc aacatccaat ccaacttctg
    62341 gatcaatcga ttcttcgaaa atcaaataaa ctgcatcccg atcttggttt ttcttaggtg
    62401 ctttgatacg tgcaatcccg tctcctaatc cgccaaccgt atctttccca gttgttaccg
    62461 aagtccctat ttggacaagc ctttcttctg tgattagctg acggatattg tttctgttcg
    62521 tttcagcgat ttgctggacg aattctttag gagtcatgtt ttcagcagct tttttttcat
    62581 gataataatc ggtcatgtcg taaatggcaa atgtcgctcc atttagtggc accgtctgtg
    62641 aaatgatatc tgctgtttcc cctgcttcct cagagatagc caagccatca ttttcatggt
    62701 attcaaattg atcgttataa tcgatatctc gaatcatccg tttatgcaac acgaattcca
    62761 cgacatcttc ccctgattct tctgccgaca tcgcatgtgg aagaaggact gctgcaagcg
    62821 gtagtaaaac aagtaattga agcatcaaac acaacagctt tttcattacc ttgctccctc
    62881 ctttttagat tgtctgacaa acaaaccata ggctgctcct gcaagcgcca tgaagaatgc
    62941 agcaagcagg atatagaata atcgtccgga tcctcctgta gcaggcaacg gattttcagg
    63001 atcgttcccg acactaagct gtaatctgat tcgatttgtc tccaaaagtt catattctaa
    63061 ctcttgctgt agatcaggcg tctctgcttc ttcgtttgga taatacgaaa tctcaacttt
    63121 tagtgtaccc gcttcttttc ctggaactac ccgatcattt tctatgtcag gttcttctcg
    63181 ataactaatt tctaaaataa agtaacctgg aagttttcta tagctgtcag gtgacttcac
    63241 ttccttgatc cgatagaccc cttccaacaa gtctgaagca ttgaataggg aagaatcgtt
    63301 tggatctggt gccaagcctc cctcgatgat ttcatactct cctgcactat tttgtttctc
    63361 aattgaaaat tctgcgcctt caagacgtcg gctattcata ctgtcaattt tcaaaagttc
    63421 caaatcgatt ggcgctagtt catcttctaa ggttacttgt agtacaccat cgatgatttc
    63481 atagccttcc ggcaagggag cagtttcgtc ttcgatgacc gtatcttcaa tgataaactt
    63541 accttcttca ttcagtgcaa actggaacac ttgatcagat agccgatacc catttggtgc
    63601 gacagattcc gagacctcat attcaccaat agacagatgc agaggttggt cgtaatttaa
    63661 atcgacatac ttttctactc ctacggcacg agaatagaag tatccgatcc caggcaaacg
    63721 tttcgattct tctggttcta acggattacc agtgtatgct cgatacagcg ggaaggaaga
    63781 atcccccact ttcctgatat cgaaacctgc accatctaat gtatggcctt catggtctaa
    63841 ttttctaact cggatctccc gataatcaaa cgtattgtaa gcagtgaatg ctacccataa
    63901 acgatcctct tcatctgttg tatacgtgag atattgccaa ttttcttcac ctgtttgctt
    63961 gagttggata gtccctatag cattatcgta aagtcgcaag atccatgtgt cattttcatc
    64021 aggttctttg aaaccttctg ggttctggct ctcaatgatt ttgtattctg catagttggt
    64081 agtttcttca ctatccttat aaacaaatga atctggctct ccgattggat gaataacttt
    64141 ctcaccatcc acgattacat atttcccgtc ttcatctact gaatagaacg tgagtctccc
    64201 tttctcttcc tctacttcgt tcacaccaga aagccctttc gctactggat atccgatttc
    64261 cagtccgtta ccatctgttt cataaagttc aaactctgcg ccattgattg gcatattact
    64321 gccttcaatt agtttattga tattcatgtg gattggcttg aattcatttc gcatttccag
    64381 tttgacatac aactcatcat actctgtgcc ttctatgtta ggctcttgta caacagaaag
    64441 cttgtgatat tctccttcat aataggaatt cggatcttta ccttccggtc cgccgactct
    64501 cgaaccagat gtatattcat ctacaagctc gtagtgacct aacatctcat cttcgttggc
    64561 tgcatatttt ttgatttgga attgatacgt ctcatctact aactgataac gtggtggtcc
    64621 agcgatctct ctgatccaaa atatgtcgct gactgctcca gtttcatctc ctaaaatcgg
    64681 catcttcgtt tcaaagatcg ctattccgtc cgtggtagtt ttacttgttt cgattggttc
    64741 ggcttcccca ctctctggat tttggtcata taatgcaaat tcgactccag ccaacggctc
    64801 gccattttga cccttcttgc tgacttggaa attacggcct ttatgttcgt aacgaatgga
    64861 agaagatggg aaatacatcc gtccagtagt gatatcattc tcataatcct ccaggttctg
    64921 aatataggcc atattgttca ctgtgcaaaa atttccgtct tgagctcccg catcaagttt
    64981 tacttggtac ttgatcctga ccatttcccc ttcacctaaa gaaatcggag aaaatttata
    65041 agcttggttt tcccgtccga catacgttgt cggagtcgcc actacttctg gtggggcttg
    65101 tccatgacgt tcttcatccc atatttctgg ctcttggtac ttcatgccgt tttctcctgg
    65161 atctagatgg taaaactgaa tatctgccga tctgccagct ccaaatggtg agacattaaa
    65221 accagtttca tcataaagtg tggcttgctg gatcgttctc ttgaaggtag aagagatatc
    65281 ctccaaggct gtaacaatgt cattcttgtt gttcgcattg taatatcgcg gtgttacgcc
    65341 atcttcttct aaatcagcaa tatttttcaa tacatttcgt ccaatagcat ctagtcgttg
    65401 tctcccgcta acgtttccat cgattcctaa accaatggag aagatacttg gcgggttctc
    65461 ttgatacttg tttttcagcc aatgatgata agcaactgtg ttgatcgcag atgacttttc
    65521 ttgcgaagta ggactgccat tcgtattgtt attagaagaa ccatcaccaa cccagtgagt
    65581 cgctttatta tctccttctt ttacctctcc ataacgatag tgtacattta cttcatcttc
    65641 tggacggtta aagtcagatg cataggtaac tggatgagta aaccctgcat tagaagtatt
    65701 cccagaaaac tcctcaaaat ttctgaacaa aacgtcatta tcttcagcaa tcttatcttc
    65761 catcacagtc cagttgctcc aagctccatt agtgctcgta cgataacttg actgaatcgg
    65821 tgcataactg aaggtcggtg tcccatctcc cacaacgatt aggatttttt ctggatttct
    65881 attttctccg ccattgtctt tatacaatgt ttcatagcca tttttaagcc ctagtgtaag
    65941 cggagttcct ccgattggtg tacgatttaa tgctgtattc tcacttcccg tcaaacgatt
    66001 gatatcattt gtcaatggaa agatgtccga actgatttgc tcatggttat tgatagctgt
    66061 actattatgg taaaaattca ccataccgat tcgaatatcc agactcgggt cagagagcag
    66121 atctttactc atttcgttta ctgcctcaat caacgcagca tttttagttt gactattggt
    66181 cccagcggtt aattcactca tactcgctga cttatctaga acaaaaacga tatcgattgg
    66241 actgatttcc tttttctcgc ccccgatgac atctagatag acattgtaaa gggttgttgc
    66301 atcttcagga tgtagatcag atgctgtgct gcttggcaga acaggttcta cccatttttt
    66361 gatgtacgcc ccgttataat ccaagtaact gttttcaaaa ttccgttcat ttccccaaag
    66421 ctgaacggtt tgagctggaa cgtttctatc ttcttcgcct gcagttgatc cattattagt
    66481 agcatagtcg taatttcgcc agttcgctcc cccgtttgta taatcactat catcgatcaa
    66541 gttctctccg tcatatggcg agcctttgtc tccttgatag cgttcattgc tttgtgtcca
    66601 atttcctaac acttttgtat agtcattcgt tgtaaacttc gggtagcgat gctgttcgtt
    66661 ttcaacttct ccgctaggat agatatattc ataggggtct tgcgtagctg ttggcccaag
    66721 acgctccaaa ataccgttga ataactggcg ttgaatgcgc tggagtgctt gaccgctggg
    66781 tacgattggt tcgtccagct tttccatctc attttcttcg ctacgttgaa tttcagcgga
    66841 atcttctgta tcagtttcat tttcttgtaa ttcttggtta tctattcttt catcaaccac
    66901 cacttgaaga ggtagttacc cttcgttcac atcggggatc ttttctgttt caaaaatcaa
    66961 tgtgccggtt tctgcttctt ttgaataaac ttttccgaca taccattctt gaccatcgat
    67021 cgtctcgact tttaggtctt ctccatcttc atcataggag gatagacctg ttccacgaac
    67081 gttttttacg gtaccaatcc cggcggctgc cgcatcgatt gctaaacgta ttctaccttc
    67141 attggcactt tccttttttt caaaagccag atgccattca agggtttctt ctttttcaat
    67201 atacttccct tcaatttttg catagtcctc atctaagaat acctcatcct cctttgtttc
    67261 tgttgactca gcagctacat ccagggtcgt catatgatag actgactgga aatatggtcc
    67321 aaatagcaaa ctgacagtta ctaactgcaa aagcttcaat tttaaccctt tcacatcctt
    67381 atactccttt caaaaatatt tgtcttcttt cacaacaatc aacaaaacaa tgcccatcta
    67441 attataattt aatttaattt taattttaaa tcaaatgata tcctttttag ttaaaaaaca
    67501 ccaattatac aacatttatt attaaaatta aattataaaa ttttataacg ttctcattta
    67561 acaaaactta agttattaag acaaatgaat aaacaactac gctttcctcg aaacaaaaaa
    67621 ataaagcaca aatgcgcatt tacgcactca tgctttattc gtacaattaa ttcagataac
    67681 ggcagcgcat aggatgccaa taacacttcc taaaatagct cctcctaaaa tgtcagtagg
    67741 ataatgtaaa agtaaaaaaa tcctcgaata agcgatcaaa caagcaaata aaaaggctaa
    67801 tattcctgca actggactta attcgaacaa cgcagctact gataaaaagg ctagcgctgt
    67861 atgtcctgaa ggaaaagaag aagtcttcgg tttacttgtg taaaggacaa gccgacgatt
    67921 tttttcataa ggtcttttcc gtcttgtcgt ttttttgata aaaagcaaac caacaaaaaa
    67981 atagatcaaa ctgccgataa gaatggctag accatattct ctagtatcag gtatcaagac
    68041 taaaacagca gcaaggagca accaaataaa accaccatta gagatattac tgataaattt
    68101 caaaaaattg atttttcgac tatccgtttt ccgttgcttg gcgaacttgt tgataatact
    68161 atcatcgatt ttagcaatca aacgcaacat gttattcctc ctttttaaga accttttctt
    68221 gcgtacgatg gataaaaagc aggacttgaa aataaaacaa gaaactgaaa cctaataaag
    68281 caaaatagat tggtcctgca aaccagaatg cgacaagaag gatcaacgtg cctgccaaat
    68341 agaaaagcgc gcttttgaaa tcattaaaaa acaagaaaaa tgcagtaatc caagaagctt
    68401 ctttttgttc cagttgaagc aagattttgt aactaaagag aagcgcgctt aatagaagca
    68461 aaaacaacgt agtatacatc aatgtatagc caattccccc accccaatag cggaaaatct
    68521 gataatcgat caatagaaga agaaaataaa cacttgctaa actatcttgc tttccataaa
    68581 gagagaagtt ctcacgaaac tttttccaga atagtgaacc gagctttttc tcttcatttt
    68641 ttttgtaatg ataaatcata tacagaactg ttcgacttgc agttcctaat gtgaaaacag
    68701 gcaagacgca caggaaccat agtagctgta aatggataag acgtggaatc cattcaatga
    68761 tttctaagaa ataatcattg gcttttttac caatcgatcg attcatcatc cttttgaacc
    68821 tcctgtcaaa tccatccctt caatgaaata acgttgtgca aaaaagaaca gcaaaatcgt
    68881 cgggatcaag acaagtgttg ctcctgccat cagataattc cattgtgtcg ttgcttggtt
    68941 ctgaaaaact tgcaagccaa tctgtaacgt gtatttttct tgatcttgga tatataacag
    69001 aggacctaag aaatcattcc aagctgcgtt gaaggaattg atcgcaatgg taatcaaggc
    69061 aggtttcgtc aatggaagca tcaaatgact ccaaatatac aaatgattcg ctccgtcgat
    69121 ttcagcagct tcgatcaatt cattattgat cgataagtaa aattgacgca tcagaaatat
    69181 attgaacgca ttgccgaaga acgatggaac gatcaggggc aaataagtac ctacccagcc
    69241 gatcttggag aataatacat attgagggat catcgttaca aaccccggga tcatcatcgt
    69301 agaaagaacc aaagcaaaca tcagcttttt cccaggaaaa tcaagcttcg caaatccata
    69361 agcaataaaa gaatttgaaa ggacattacc gatcactact agcacagtga tgaataatgt
    69421 atttcttgca tagcgccaaa aaggaaaggc ggcaatcgta tccagatagt tttcccatac
    69481 gattttttct gggaaaaagg tcggaggata acgaacgatt tcttccattg gtttcaatga
    69541 agtaaacacc atccaaagca atggaatgat caaaatgatt cctattactg tcatgaggac
    69601 ataacttagt atttttttgt ttgccgattc acactggtct ttttgaaata atccatcatt
    69661 tgccgtcacc tccagaataa tagacccact taggtgcaag cttcaaattg acaaacgtca
    69721 gaaccaacac gatcagaaac aggatcattg acatagccat cgcataaccc atatcaaaag
    69781 ctacgaacgc cttgttccac atatgcagat tataaaaaag caaagaattt gcaggtccgc
    69841 ctgttccatt tttcgtcatg acataagctt cttgaaaaat ttggaaagaa ccgatcgtag
    69901 aggtgatcac atcgtaaaaa ataataggag tgattaatgg caaagtaata cttttgaact
    69961 ttccccaaac gcctgctcca tcgatttctg ctgattcata taaagatcta ggaacatttt
    70021 gtaatgtagc taagtaaagt agcattgctc ctccagaact ccatattttc atcaaaatca
    70081 acgcaggttt cgtccattgt ggatcaaaca gccaagctgg tccagggata tggaaccagc
    70141 ccagaaatgt gttgatcaat cctgcagatg gagaaagcag ctgcatccat aagatgtaga
    70201 ctgctactcc tgataagact gccggtaaat agaaagctgt acggaataca ctgattcctt
    70261 tgattttttg attgagtact gtggctaaaa acacactgaa aatcgtcgtc agcggtacat
    70321 tgaagatgac gaaataaacg gtgttgtata acgatttcca aaataaatca tcgtgaacga
    70381 acattctttt gaaatttgct agaccaatga aattcatctt ggatgtcaaa ttataatcgg
    70441 tgaaactacc aataactgaa aaaagcatag gccctagcat aaataccaag aacccgataa
    70501 taaaaggcga gataaataaa taggcccatc ttgcttcttt tttctttcgg atagataaac
    70561 gcttcaaatt ttcttgcctc ctctgtacct agacagtcaa aaatggatta ttgattttgc
    70621 ttgactaagt tttctactgc tttttgtgca tctgccaatc cttcttttgg tgattttgtt
    70681 cctaaaagaa tctggtcaat ctgttcattc actaatgtcg tgtaatccgg agcatctaaa
    70741 ggaactggtg tgatcaccgt atttttaaag ttttcgtccg ccatttgata gatcattttt
    70801 cctttatccg ttaggttgtc attattcact aaattctcat tggctgtctt gctcgccatg
    70861 atatcaaaac ttttttcgcc gaatttttct tgtacttctg gagaagaaag atatttgatg
    70921 aattcataag aggcctcagg atcttttgct ccgtatggta cttccaagac gaatccgcca
    70981 ccccacgacc aatggcctga accttcttct ttttctggga gctgcatcac gccaaaatca
    71041 aaatcatccg gtgcattttc catcaaacta gagtaataat tgatattttg ggcacgcatg
    71101 gctactaatc cggaaataaa tggatcagat acaccagacc caaattcggc ttctaattta
    71161 ttgatcgtat ttttcccata ataatcttgc cagtcttgga tccactccaa ggcttccact
    71221 ttatttttag tatcaatctt gactttttca tctttgtcaa accaactagt cccgttatct
    71281 gcgtttagcg cccatacatc agcccctaaa ttccataatg gataaaaacc gatgcgtgta
    71341 aattcttttc cttctttttt atctagttta cgtgctgttt cttctaattc atcccaagtt
    71401 gtcggtagat cttgttcact gattccagct tctttaaata tctttttatt ataaaaaatg
    71461 acttgtgtat ctgtattgaa tgggatcgca taaggatcac cttcatattc tactgtatcc
    71521 caaagctgcg gataaaaatc cttagaagtg tctttttcta catatttgga gagattagtt
    71581 gcttgctgtg cttctgctct ttgggcaacg gaatttatgt cctgtacaat aacatcgggt
    71641 gcatttccag ctgttattgc agataaagat ttagtccaga tgtcacccca tggctgatac
    71701 ttataattta catggatctc gttttgtgat tgattgaaat cctcaatgat ttcttcgata
    71761 gcttcttttc gtgcaccgga tccccaaaag gaccagaaat caatattttt tcttccatca
    71821 cttgtttttt cagaagaatt tgctgcactt gaactggcat cgcttgcatt acttgatccg
    71881 catcctccta ataaaaacaa tgctgaactt gccagcaacc ctgtaaacaa taattttttc
    71941 atattttacc tccaaatttt aatgtaaccg atgccggttt taatataacg atatcatttt
    72001 gttctgaaaa taacaattta taaggtatga ttctaaaaaa attattaatg ataccaatac
    72061 tttatataat tcgcgagcgc tttctttgaa ttttttaatc tttcgtagca gaatgagaat
    72121 gtattaaaaa tagattagga ggaattttga tgtttagaca ccagaaagaa ttgcagtttg
    72181 aagcaaaacc agatcgtccg aatccattaa tcgcgaaata tctgcaggag ctgatcggcg
    72241 gccaatatgg cgagatgagt gtagctatgc agtacctgtt ccaaggctgg agctgccgag
    72301 gagaagaaaa atataaagat atgctgatgg acattgcaac agaagaaatc ggccacgtgg
    72361 aaatgttggc gacaatggtt gctcgtttat tagagggtgc gcctgttgaa gatcaagaag
    72421 cagcgatgca aaaagatcca acaatcggtg ccattatctc tggaatgaat ccacagcacg
    72481 cgatcgtagc tggcttagga cctcgtcctg ctgacagcgt gggcaatcca tggagcggtg
    72541 cctatatcat tgcgagtggc aacttgttag cagactttag agctaattta aatgccgaat
    72601 cacaaggaag acttcaagta gcacgtattt acgaaatgat cgatgatcgt ggcgtaaaag
    72661 atatgctgtc tgttctcctt gcaagagata gctatcatca aaatctatgg gaatgtgcag
    72721 tgaaagaatt agaagaaaaa gaaggttcaa tcttagtccc aagtactttc ccgcgtgaca
    72781 aagaacgaaa agacattgct tatgacttct ataacttctc agagggagac caaagtagtg
    72841 aaggttcttg ggctagtggc aaagcactgg atggcgaagg cgaatatcaa tggttgaaag
    72901 aacctaagat cgaaggcgct gcaccaaaat tagaaccagt aacaccaaaa atgtatggga
    72961 cacctccatt caagaaataa atatctaccc gtagaaacac ccgttttttg ttccacacgc
    73021 tttgtgagca aaactgacta aagtcattaa tcataaccac ccttcaaaag ggtggttttc
    73081 tctagagcta taagctcaaa tcaccggcca gcgcctaaag acgctggctt tcatatttta
    73141 tgttcaagcc atattgcctt tgccagtttt gcccacctct taaaaggttt atgtactact
    73201 ccttagccct taaaaggatc gtcttactct cgtacactca gcttatctaa cgcactatca
    73261 tgtttttctt gttcttgaat gtactttttg atggtcgctt cattttgtcc tacttttgtc
    73321 acatagtatc cttccaccca aaagtgtcga tacccaaatt tatattttag atttgcacaa
    73381 tctcttgatg atctcctgaa tattggctcg atattgatta taaattattt ttcttctata
    73441 ctttggtgtg aatacaatgt ggtatttaca catctacttt gtacgggcta aactatttcc
    73501 ctttattgct ccacccgcat agcaagtggt tttgtatttc aatcgctcgg cgcgctcaat
    73561 taggtctaaa gacaataaat ctaaaaaccc gctgcttcac tgacagaaac aacgggtttt
    73621 cagaaaaaaa tgaaatgaaa aagatctctt acggcaatct attttatttt tttgattttt
    73681 tataaatgga aaatgcttca agaagtccaa gaaataaagc cgtataaaaa caagaaccta
    73741 tgaaatcttt atttattaga tattcaacag aaatcccgat aacactagcc aacaatatat
    73801 ttatcagaag tgtaaaataa ggatgctttt tatagaatag aactagtgtt gttttcatag
    73861 actctccttt cttcatattt ccaattaatc acaaattcac ggcattacta gaaaaattaa
    73921 aggggcgcag aagtggaaaa atactcttcg actttcccta caaaccaggc catcttgtgt
    73981 ttaataacta taccaaatct aaggtacctc taaatctaaa ttccatttgt ggcggtgacc
    74041 tccaattttt aactcttcta tctcccatcc agtatacata accttgatac ttcgaccact
    74101 tatatatcga acacacaaat acctatccat tgcaggagta ctacctaact tagttgctac
    74161 ttgcatctaa ataacagctg aaaagatagg acttactctt agtaaagtat ctgaactatt
    74221 aatttttaaa ctatcatttt tatcctcaac tacatgcaca tctgttgcaa cttcactttc
    74281 tgtctcatcc agataaatga ttaaggaatc gggaattgca atatcttcag ctgacgctgg
    74341 aatagttgag ctaaattagt catcatatct ttattataaa ataaccaaca gcaaaaaata
    74401 caatgaaaaa caaacttgga actaatgtat cattaataaa tgttgaaaaa ttcagcaact
    74461 cattactgta tgattttagc agcccaacca acatataccc tataaaagct aataagatgg
    74521 ttaggaatcc tttagaattt ttactcattc atagacactt ccttaaataa cttttattat
    74581 agaaggtatt gtaaataata atattgacaa aaagtgactc aaaataaaaa aaaccttaca
    74641 ttatactgga atgaactgta ttgatagtgt acctaaaagc tctactgaca taagatcgtg
    74701 taatcggtaa agtaatttta ttaattatac gggatgtaat caattagaga ataaactaat
    74761 cataaaaggt acttttacat tcataattgt cgctttgaga ttctactttg gttcactatc
    74821 tgacccaatt gcacattttc gatcattaca agtattggtg tcgttagaac aactaaataa
    74881 aaactagcgg tagatttttc agaatctatg ctaatttctg tatggatgtt ccagtgatgg
    74941 caaatttctc ttttcattgt ttttcttgtc gcatgatatg cctttttgtg ttattcagtt
    75001 aaactataga aattctttcc tagacagatc ttgatcccaa attttacgtt tttgagcatc
    75061 gatatagttt aaaatgacat tactcatatc taaagagttt agatttttta ggactaaaac
    75121 tgtcagttgt tctttttctt ctttctgtta aagtattgtc gcgacttttc gtatacgtta
    75181 agatatgtcg tgaaaaaaca agttttgtga cacaaaaaaa cgaatgactt gaggaaatca
    75241 cctcaatcat tcgtttaaaa tgctatatat tctttagttt aagatacgga aattaatgcc
    75301 atcgaccaca ctagtagaat gaacgacatt tacttggcct ttttttaatt tcgttatgtt
    75361 tagcatataa aaatattata gagtttactt acaatgctta aaacatatac tgtataatct
    75421 gatcaatttt agccatgtct tgcaatggta agttttctat ttttttgagt tttcgttcct
    75481 taaaatcaag agattttaat tgtgtaataa ttacttgtcc ttttatatct agctcttcag
    75541 gtaatgagta acgtgtcggt aaattcttta tagtggaagt aattggacat atgaccgaaa
    75601 acattgtttt acggttaaat tcataacgag agacgactag tcctggtcgt cttttttgaa
    75661 tttcttttcc tacggaggga tcaaaatcaa tccatacaat atcacctttt ttaggaatat
    75721 aaattctttc ttctgacact ataaaatttc tctcccttca ggagttaaat cttcccattc
    75781 gtctttctca taatactcgg cctcttcccc accactaaat ggatcttcaa tttttggaac
    75841 taacgtaatt gttccatcat cagaatacac aacgatatat tcttggtttt ctgaaggttt
    75901 ctttccgtta tcagaaggta aagttaccac tacagaactt ccttgtaatc tagattttgt
    75961 aacaagcatt atcatcactc ccttaataaa agtatactat ataacactaa gtaacgcaaa
    76021 attccccttt gtaaactatc tagaaaattg ttttgtttaa agtatatctt attggatata
    76081 aatagaaata aattgtagcc agttcatttt ttctttaact aaaaaaataa tccaagaaac
    76141 attgaaccta tggatccaaa agctacccaa atactatagc taaccccccg ctaccttcaa
    76201 ttttgcagat aaaacgcttt gggagaaaat ttcaaagaca acaggccatc ctatcatgcc
    76261 cgattataaa caaaaagctg gctattcctt ttgctctgac aaatttcaat tgggaaagtt
    76321 cacgaaacta gcaggtgaag aagtttcaac tgttcggatc aaagaatgcc cgcttcaaat
    76381 agaaacattg gttcaacgaa tttcaactag acaagacttt gctattgtag aacgtgagat
    76441 cgtagctatt tttgtagaag aagggatttt acatgatcca actcatatca atgtggataa
    76501 atggcaacct cttatctata aattcagaga atatacaact gccaaccagt cgttaacttt
    76561 gaattttaga ttccaagaat tcaaagagtc ataatgataa acatcgttag gtataaataa
    76621 aaaagactcg cagcacgagt aaaaaacaaa tagaagctat acattagaaa ggtcgactgt
    76681 gaccctatag atgcagtata tgcagcttat gagcatttct tctgttctct ttgtttttgg
    76741 gatctgtgct gaagtctttt tcgttttttg ccgctctttc tttgaaaaat cgattatgtt
    76801 ataccttctc cattactaat tcaggcatct gctgagtaat gatttttcgc gcaaaagaaa
    76861 tatctgttac ccaaggttcg atttgttctt cagtcaagac aagcggcatt cggtcatgga
    76921 ttggtgcgac tgtgcggtta ggttcagtag tcattatgat tgattctgcc attttttcat
    76981 cctgatggct acgataaaaa ccgccaatat acactatttt ttccttattt gaaaacataa
    77041 atttgtcttt ttcttcattc cactcattgg gaaaacacaa cgattttgca aaaatggttg
    77101 atgaaaggtc tttttttctt ctactgtctc tgcacgggca ttaatcatca attgtccttt
    77161 tttaaatccg gtaaatcccc acttcatgat ttccggagtg aggatgtttt cttcctcttt
    77221 tcttaacgtc acaacaagat ttgacggaaa aacttctcca gctgctaatt ctgctgcctg
    77281 cttcggttgt ttcgtctggg cttctcgata ataattctga aggagctctg actctagatc
    77341 aaaaaaataa cgaccacaca tcctaatccc tcccaatctt tttttctatc atacactgca
    77401 acaagaagtt cgcaccaaca aaacgctttc aatttttgta gaactaaaaa agttgtgaca
    77461 agtgacaaac tctccagtga atggtattct cctgccaact cctcggtcac aagtcacaat
    77521 attcaacaaa catgagaagc tgctttttga aattgttcct tgtgactcgg agtgaaacgg
    77581 caggcttacg acctctgggt aaacggtgtt caaaagccag tttctcggta ttaagccaaa
    77641 tttatgcaaa aatgtagaaa gctattttca caaaattttt cttaatactc gaaactaagc
    77701 gactttttca caacctcttc cttaaacggt gttcaaaagc ttgcatctgc ggtaataagc
    77761 ccaaccaaac gaaaaatatg agcagctatt tttatttggc tgttcttatt acttgatgca
    77821 gggcagcttt ttcacaacct ctccactaaa cggtgttcaa tcagctaacc ttcggtatta
    77881 gctcaaaaaa cggcaaaata tgaggaacta ttttgccgtt tgtttctcta atactcaggt
    77941 caaagcgctg atttcacaac ctctaataca cggtgttcca gaagtagctt cttcgaaaaa
    78001 taagccgaaa tttcacaaaa atttgagaag caattttcgt aaattccttc ttatttcttg
    78061 aagctgacca cttctgtcac aacctctaat tattaaagaa ccttttgcga agttaacaat
    78121 ctttctttga tcaattgaaa attctgccta agtagtgata gatcctgtgt gactttcaac
    78181 aataagatac ttccctggat ttcagcaatc aacgctttgg cttgacggtc tgcttcttca
    78241 tcggacagtt tttcttcaga aagtgccagg atattttgtt tcgtatactt gacccattga
    78301 ttgactaatt ctagtagcaa cagacggtat tcttcatcca ctgtactcaa ctcaataatc
    78361 aaattaccta caggacagcc atgataagtg atctgtgtct catgatcagc gaaaatccag
    78421 tccaacattt cttctaatgc ttcttctggc tgttttccag catttaagat gtcttcgaac
    78481 aattctgtct gccatacgtc catatgcgca tggatcaccg ctagacaaac ttcttttttt
    78541 gaagaaaagt aataataaaa ttgacctttt cctgtatcag aagctgctag aatatctcgg
    78601 attgacgttt catgatagcc ttttttataa ataagatctt tggtcgcttc caagatcttt
    78661 tcctttgttt tcaatgatat tctccttttt catttctcat agtcctatat tatacagtaa
    78721 attcatcatt ttttcttctt aatcgtttaa aaaagactgt gccaaattat ctgacacagc
    78781 cctcactata aaactgttct catatagcta gatgttcatt gattcaagaa ctgcgaggac
    78841 aaaagcaatt cctatcttat gatagttgct ctaatacttc ctctgttgtc atcacttgat
    78901 ctgcaataaa gccaaagttc gtcaacgctg catccattgc ttcttggcca ggagcaccaa
    78961 ttgcatctgt cgctaccaca acattgaatc cactctctac caattcacgc atatgggaat
    79021 cgctacacaa gtttccgttc attccaccaa gaattactgt gtcgattcca ttttttctca
    79081 attggagcgc caaatcattg ctttctggtc caaagatttt atgaggagag ctgatgatcg
    79141 tattttcatc caaataaggt ttcaattctt cgataaaatc ggctcctgaa ccttcttcca
    79201 ctgattcata ttgacttttt ctagcaaaca tctgctgctc aagcatcata tgttctcctg
    79261 caccgccaaa ttgccattta tggtcatgtg ggtaaaaata atgaggagaa ataaagagtt
    79321 tgtatccttt ttcttttgct tgttttacca tttcaatcat attttcgatc gtattgtatt
    79381 tttctaagat atcttttgtc aaaccaaagc caccgcctgc tggtttcaag aactcgactt
    79441 gcgggtcagt gagaactact gctgtatttt tattattgaa catggtggat tctccattcg
    79501 ttatttattt taatacatca tttagagctt cactcattgt cggatgagaa tagatttgat
    79561 ctctcaataa cgtataagga agttttccat tcatagctag cgaaatcaag ttgatgactt
    79621 catgagaatc ttccgcatag atacttgccc ctagaatcaa gtcagtttca gggtcgacta
    79681 aaactttgaa tacaccttta ggatcttcta atacttgtgc tttagggaca ccgcttgtca
    79741 tatacttgaa taatttgtaa ttgacgcctt gtgctttggc ttgtttttct gttaaaccta
    79801 cattggataa agtcggagtg ataaatacac tgtaaggcac agctttccgg ttattcgttg
    79861 ttcgtttatt ctcgcccttc aactgatcca taatgattcg ataatcatct agagagatat
    79921 aagtgaactg caatccgcct ttgacgtctc caatcgccca aatgttgtct gcatctgtac
    79981 gaaggtattc atccacagcg attgctccgc gatctgttag tttaacatct gtattttcta
    80041 atccaagtga tgctgtactt ggttttcttc cagttgcagc caaaactttt gacgcttgga
    80101 ttgttacttc ttggccatct tctgtaaagg tgacggcagc tgttgattct tggtctgcta
    80161 cttgatctac agatacacct agatggaatt cgattcccgc atttgtcatg tcttctaaaa
    80221 tcatttgcgc gatatcttca tcttcacgtg gaagaaattc agaatgggca tcaagaacga
    80281 caactttaga tccgtattca ttgaacattg atgcaaattc caagccaata tatccagccc
    80341 cgatgatcac taatttttcc ggtaattgtt cctgatccat cgcttgcgta gaatcaatca
    80401 agtagcgact tgtattcaat cctttgattg gtaaaatgat tggttcagaa ccagtattga
    80461 tgaaaatccg ttcgccttca acaatcactt tttcaccatt attcgtcact tcgatttgat
    80521 ggttagaaag aaaacgtgct gtaccgtcca tcactgtccc agttgcctca tcgctgatca
    80581 tatgataatt tttggcgcga agcatgcccg tcaatttttc tttccgagca acagcctctg
    80641 taaagtcgat tcctctttct ccattgaaaa tcaatgattt agaaggaata cagccgatgt
    80701 tgatacatgt tccgccatac atacgtgttg acttttcaac gactaaaacc gattcacctt
    80761 ttgaagctaa cgccttcgct aaagtcttac cgccctttcc aaaaccgatc acaatatttt
    80821 gatatttttc catcattttt ccctcgcttc ttttttacct accgattggt acaaaaatat
    80881 gataaccgat aattgtctat tctccaaatc atctgcttta tttgtcaaaa aaaaccagac
    80941 aaaaagcggt cctttcacgt ttttagtctg gttcgatttc ctttattctt ctaaacaatc
    81001 gttacttcta catcgatatt tcctctagtt gctttggagt aagggcagaa ttcatgcgca
    81061 tcttctgcaa ttttttgggc ttcttcttcg ctgatgccat cgatatgcac ttctaatact
    81121 acaccgatct gatagccgcc atcatctaaa ttataaagag agacacgtgc ttttactgtg
    81181 gactctgctg tcattcctgc ttctttgatc atatgttgta ccgccccatt gaaacaagaa
    81241 gcataacctg ctgcaaataa ttgttctgga tttgttcctt ctgcatggat tcctggagga
    81301 gtgattttca tatgcatcga gccatttggt gcctcgactt ctccattgcg cccgccatgg
    81361 ttgatcattg ctgtttcgta tgcttttttc attgtactgc tcctttcgat tgaccatttg
    81421 ctacttggct ataattatag tgtatgacaa gtaaggcgct ttctacaaaa attctgctta
    81481 ttcgaatacc agaatgccgt cttctactat ttttccaaaa aacaaaaaaa tactactcgt
    81541 gaacaacagc gtcatatttg ttccaaaata aatagcaatc ttttctacat aatcttttat
    81601 atgattgatt ttaagataca tatataccag aaagttgacc ccataaacca atactgttaa
    81661 aaaaataacc atattcgtta ccattttttc ctccttttgc tggtctccct accagcactc
    81721 gatttaacca taccactttt tttgccgtcc aagcaactag cctttcaaaa agactggttt
    81781 attctgctgt taatgattca agatcagaaa aatgtccgaa taattttgct aattttacta
    81841 acgccaactt gttctttccg aattcatcat tttctatctg taatactagt aacggctcat
    81901 gtaagcttaa acggatcaaa aaccagccgt ttccgtatgg ctcttctaga tcatatcgaa
    81961 taccttcttc attttccggg tcgaagttca tccctttttc ttcttccaac agtcgcttca
    82021 tttcttctaa tatcttgttt ccttgttcgc gtggttcatc gctgaacaat tttaatcgga
    82081 tttcttgtac ttctacgggc tgtttcaact ctttgatttg ttcatctaat gtgatacctt
    82141 ttctttttaa ttctggcaaa agcatcagga tctttgcgat gacatatgca ccatcatcca
    82201 gaaaatagtt ttccttgaat gcagcgtgtc cgcttgtttc gatggctagc tgtgtatctt
    82261 tcccaagacg gttaagttct aatgctttat tgattacatt tcgatagccg gaaatataac
    82321 gaacttggat gcctcctttt tcttcaatga atctttgtag atgagaagaa gtaggggaat
    82381 tcgtcacgat tcttgttcct ggatgctctt ttaatacgat tgtacttaat actgcgatca
    82441 aattatttcg attgatcact gttccagaag cactgacaac tgcagaacga tccacatctg
    82501 tatcgaaaat gatcccaaga tctgcttcat ttgctaaaac agcctgcttg atactttcca
    82561 tcgcttcttt attatcagga tttgggatat gattaggaaa tcggccatct ggttccaaaa
    82621 attgggaacc tgttgaatcc gcacctaagc tattcaatac tttttcagca aagaatccac
    82681 cagcaccatt tccggcatca acaatgattt tccaaccatt tagtggtttg ctttctagtg
    82741 ttccaatccc ctttttaatt tttgtgacta aatcttgcgc ataaggtgtc aaaaggtctg
    82801 ctttttctac gcttccagtt tgttcgcttt ttattttttg ctgctgtgat aggataaaag
    82861 caatatcttc tttttctgct cctccttctg aggtaaagaa ttttattcca ttataataat
    82921 agggaagatg gctagcagtc agcataaccg cagcatcgca cgagaactgt tcaaattgag
    82981 tggacataaa catagcaggc gtagtagcta attcgaaatc gatgacatgt atcccttgtt
    83041 ctttcagact ttggatcaac gcctctttca gtgctggtcc gcttatccta ctgtcatgac
    83101 caatcccaat cgtccatttt ttatttggat cggttgattt cttctttttc tttatccagt
    83161 ttgctagtcc ccagccgatc ttttttacca tgtctgtcgt caagtttact tcatatcctt
    83221 caactggtaa tgcgattcct cgaatatccg atccattttg cagcgctttc atatctttca
    83281 tataaaagtc ctcctcattt attccctcat tttttccagc ttttctgcaa atcgctgtgc
    83341 ttcttcttct gagcggcaaa taataatgaa tgtatctaca ccggccatcg ttccgacaac
    83401 ttcagggtaa gccacttcat ctagccaatt cgttaccaca tcggcaccat ttcgttcagt
    83461 caatacgata accatgaact gaacagactg gatacgcaaa acctcgcgtc taattgctgt
    83521 acgcaaacgt tcttcattta aagaaacaga tggctggtta aataatgtat agcgtactat
    83581 tttgttttca ttttgacttt ttactaactt catttctcga atgtctcgag aaatcgttgc
    83641 ttgagtcaca tcggcgcctg cttcatgcag ccgcgcaagc agctcttcct gtgtcccaat
    83701 aggttgttct gtaatgatct ggcggatcag tgcttgtcgc tgtttctttt tcatattaga
    83761 cacctctcaa tgttgattat agcaaaagat aagtaatatt tcttcatatt ttggtatttt
    83821 ttacttttat tttttgtttt cattcaggtt gctaaccttt ttctatttta acacgcaaaa
    83881 tcgtcttcat tttttcaggt gctgattttc ttggatcgct gatgtaaatc tctttgtgtt
    83941 ctttagaagc tctttcatag ccttcttttg cgatgaatgc ttctaatttc tcaaacgttg
    84001 ctggttcttc ggcatagggc ccgacgtgta agatttgggc acaaagacct tcttccatct
    84061 ttttgaatac tacttgttct ttcaagtctt ccggaagttt gctagaacgc tgaatggctt
    84121 cttgtgctat cgcttctgta acaaagtcag gctgtcggat catcaattga taagaaaaat
    84181 gttctttttt catcactggt tcatgcaaat acttttcttg cagtccccat tgtccttcca
    84241 gtggatagac agtatacatc tgataatcag gaatcagcca atttttttta ggcgacatgc
    84301 gtattgcata gctgactgca tatagacagg ctactcttcg tttaaagtct tcctgattcg
    84361 ggtcgccgat ccctctgatg ctaaagaatg attttttagg aacctctagt atttgcgggc
    84421 tttttttcat actatagctc ttgtctttac gccattcaat tttttccatt tttcttcctc
    84481 cgcgaaattc catttagtta tttattatca tacctctttt tgagtgactt ggctaatcgt
    84541 gttgacacta tttttcagtt tgtgctagaa taagtgaagt aaataaatcg tacagataac
    84601 acgtttcggc gtgtcgagag agaggcggtt tctattttta taatagaaat cactctcttt
    84661 ttttacgaaa ttttttagag gtgatgtaaa tgacaaaaca aaaacagctg cttttagtac
    84721 ctgcagtaat tgcaacaggg atgatgtctt ttgcgggcgt attgatcgag acggccatga
    84781 atgtaacttt cccaactctt atcagacagt ttgatttaac gactgcacaa gtccaatggg
    84841 taacaacgat ttatcttttg atgatttcga tcattgttcc gctgtctact tatttgaatc
    84901 gcaattttag tctcaaaaaa ctctttttag cttcaaatct gcttttcttg gcaggtataa
    84961 tgatcgattt cttctctcct accttcatgg tcctattgtt tggtcgattg ctccaaggtg
    85021 cagcgacagg tatcgctctt ccgttgatgt tccatattat cttgacattt gcccccctca
    85081 atcgacgagg cgcgatgatg ggtgtcggta ctttgacaac ggccattgct ccagcaattg
    85141 gccccactta tggaggcatt atgacttcac attttacatg gaatcatatc ttcctgtttc
    85201 ttgtgcccgt tttgtttctt tctttgatta tcggctggtt tgctattccc gagatggcag
    85261 tacaaaaaag tggttatttg gattggataa gcgttttagg aatttgtctt ttgtttagtg
    85321 gaagtctaac atttttgagt acgttgggaa cagtttccag ctggattgct ttaatcatcg
    85381 gcggtattgg ctggttcctt ttttactatc gaagtaaaaa agtggagcat ccactgatcc
    85441 gactgtctat tctttcaaat aaaacattcc gcttgttttt gattggcttc ttagtttatc
    85501 agtttttatt acttggtgta tcttttgtct tgccgaattt ccttcagatc gttcaaggaa
    85561 gtagtccttt tgtcgctgga ttagcgatgc ttcccggcgc agcggttggt gctttgcttt
    85621 ctcctttttc cgggaaaatg ctggatcaat atggtccgaa gaagccaatt tttgctgggc
    85681 tgattctttc tttgattggt tggctagcat tattcctact cataggacac gcttcagtgg
    85741 gtgtattgat tgcttgtcat gtgttttata tgatcggtat cggattatct tacagcaata
    85801 tgatgaccac cggaatgaat gcactgaatg aagaactaca aggagacggg aacgcaatgt
    85861 tcaatacctt gcagcagttt tctggcgctg tggctacttc attagtagcg gtcattatca
    85921 attacgtcca gcatcatact tcccataact atgaagtgtc tactacatta ggatcaaaag
    85981 cagcattagg cgtcttgttg ctgttgcttc tcgtaagctt tgctcgattc gcctattatc
    86041 tgttctttgc taaaaaagcg tagattccat atacggcagg tgttgcatct gccgtttttt
    86101 tgtgtgaaaa tggttgtttg taaaaggagg cttttttatg gaaaaaattg ccattatcgg
    86161 tggcgggatc attggtatga ccctagccag ttacttagat acatcaaaat tcaatgttgc
    86221 tttatttgat gaagggacag gacaggcaac taaagctagc gctgggatta tctccccttg
    86281 gttgtcgaaa cgcagaaaca aacaatggta tcgtctggct aaagacggcg ctgctttttt
    86341 ccctaaactt ataaaagatt tccaacttga tcaaacgatt tacgcacaat cagggacact
    86401 tttgcttcga cctgaaaaag atttagctga attggctgtt cttgccgaga aacgaaaaga
    86461 agaagcgcca gaaattggaa acatcgaatg gctttcacct gaacagacat ctcaagcact
    86521 tccgttattg aaaccagcag tttcactgcg tatcagtggt ggtggtcgtc tggatggaaa
    86581 agcatattta gaacatcttg gtcagcgttt agcacaaaaa caaatggagc agatccaggc
    86641 aaaagtcact ttgcataaga agagcgattc ttggctcatc aagggaccgt ttggagaata
    86701 cacagctgat cgtgtaattt tgacacctgg cccggcactt aagcctttat tacaagaatt
    86761 aggctatgct gcagatatac gtccgcaaaa agggcagctc ttagcatttc agacatctta
    86821 taagatgagt caagactggc ctgttgctat gcttgacgga gaagctgatt tcattccttt
    86881 catggatgga aagatccttt taggtgctac ccatgaaaac gatcaaggct gggatttggc
    86941 tcctactagc gaagcttata agggattgac taagagtaca gaacagttct tgactgatcc
    87001 agatcagata aaaaactggc catacgagtt ccgtgtaggt acccgtgctt atacgtcaga
    87061 tttttcccca tttttcggcg tactgccaga tgatccaagc ttactggctg ctagcggtct
    87121 aggctcttct ggcttgacca caggtcctta tatcggctat ctattagcca acttcttaaa
    87181 tactggtcat tggcctacgg aagattatca aaaggacatc tccacctata ttacgaaaaa
    87241 tccatcatag aaaaacagct ttttcaagta aggatcccga gcgatattgc gcatggatta
    87301 cttcttgaaa aagctgttat tttagttcaa tttctgaatc aaattctcca aactttcttt
    87361 tgcttcatct ggcaagagat cttttcctat ctgagcttca atgaatcgta aacgaatatc
    87421 aagtcgttgt ttcaccagat ttttatagga cgtatcctca aaagaaacag gaaaatctgg
    87481 tataggtaaa tagtggatgt cttcaaatgg accaaacgac ttgaattctg ccgtttgttg
    87541 cacgattctt tcaacgattg acaatgtcgt ttcaggtttg atttttttat catcgaaata
    87601 tccagtattc aggacatagc aggctgtttg ctgtttcaaa aacaactctc gaaaagcttg
    87661 atagtcttcc ctaagaggat agacacggaa aggattagca aatggttcaa tgactagctc
    87721 atctagctgt ctttttgtag tgatattttc cgcgtctgat cgttttgttg ctaatgttgc
    87781 accaaaagac gctgctaaaa ctgggtcatt gatcttgata attggcggaa gcgaatcatc
    87841 tttcatgatc caaaaaacag catcgatctt ttcgctaaga tgatcgactc ggtcgggtgt
    87901 cgcataacgt gatttgactg tccgcccatt tccgtttcgt atatctcctg ttactaggac
    87961 tttttctcct ttacttgtac atgtcacgcc cacattctga caagtaagga aagaagaaat
    88021 ggccggatca tcagacggat agtcttgtgt tttatcaaag taagaaggtt ccaaggcagt
    88081 agcaaaacca ttttttcgag aaataacgaa agcatcgtca tgcaagatcg aaacagagtg
    88141 accttccgta tgttttgcta aggtaatcgt tgattttcca gaaccggaca acccaaatac
    88201 agccatcgta taggtctggt cattactagc atattgtttc atcccaccgt ggcaggcaat
    88261 aaagccattg cgatttccca atgcccaagc aagcgtcaaa gtcgcttttt ttaattctcc
    88321 aaagtaacgt aatcctagca cagccgctgt attatggaga gcatcaaaca aaatgagtcc
    88381 atttggaaat gtttcatgtg tccattcggg atcacaaaag atataaagat ctccctcatc
    88441 aaaggaaaca gacttttgat aagtctctaa gatcttcgaa ttcgctggct gaaaattcag
    88501 caaataagaa tacaaattgt tctcaaatcc ttctggaatc agcaaatgac tttgcacaga
    88561 aaattcttca gataggccaa cgattacttt tgtatggtaa aactggcgct tgcgactttg
    88621 atacacagct tctcttaaaa ttttctcgta tttgctttgt tccttgtcta agtcctcaaa
    88681 gatccgccga gcacttgctg ttcttcccac aatgcttcca tcattgaata ctagtgtcct
    88741 aacatcagct ggtaaatcta gttcttcagc atgtgagatt gttaaatctg tgatgatcgt
    88801 tcctggactc ccttttgcta gttgataagc tgtcttccta tcaaaaactt catgaacatt
    88861 attaccgtaa aatgtcgttt ctacaatcga tcgaatactg gataacagtg gatttccact
    88921 tgtgatttcg tttaattcga gactctcttt tgtactcatg gctcctcctc attccctaaa
    88981 caaaaaaacg ttttctttat tatacattat tcgagttttt atttgtactg ctgcgctgtg
    89041 ggaagcaaac gagttatttt tcacacaaaa aaaccgagaa cttgaataaa caagtttctc
    89101 ggtttcatca ttttcctttt atcggcttag taccagccgt ttgctaacca gaatgtttta
    89161 gcagcatccc atgaaccata acgagatgtt acatattgtt ctgctacacg ttcttgattg
    89221 gcagctgaat agtcgccgtt taagtatgaa gcatctaatt gataacggcc gatgtaacgt
    89281 ccgttagtag ctgtgtatga accgcctgat tctttttgtg cgatccattc ttttgcagag
    89341 cttgaagttg gcgctgttgc agcagctggg gcagcaggag ctacttcaac tgtttcaaca
    89401 ggtgcaacgt atgtatgttc ttgcgttgct gtttcagttg tagatgctgt attttctgtt
    89461 gttttgtttt ctgttgttgc tgaagaatca tttgaagttg ggattgttaa ttgttcacca
    89521 acataaatgc ggttgatgtt tgcgatcgaa tttttttcag caattgcatc gatcattgag
    89581 ttgtctcctg caaatttttg tgagatctta gataatgaat cacctgattt tactgtataa
    89641 acttcatcag cgtgagcatt tgtagttcct acaaacattg cagtagcacc agcagcaaaa
    89701 gttgtaccta aaacaatttt cttaaatgaa ttcatattaa actccttttt ttctccgttt
    89761 tttattcttt cgacgctatt aactttatca tttagaaata tttcataggt aaaagaaaca
    89821 tgacatttaa tgacaaaata acgaattatt taatatttgt aacatttaaa caaatatttt
    89881 tttgatacaa aaccataaaa gccttgttgt ataagcaaag taatcgtttt tctatgtttt
    89941 tttatttttg aatgaaaaac gcagattctg taacattcac tgcaataatc cataaaaaaa
    90001 agcaaaaaaa tttttgattt ttatcaaatt ctcttaaaaa aatgtaaaaa atacaaaaaa
    90061 accagtaatt gttacaacaa ttactggaca aaaactttga ataatgttaa ctattttttt
    90121 attttaactt tctccgcaat aatttctggg catgttccaa ttcgtttata acgacttctt
    90181 ctgtttcttt agctaatatt tcatctaata catcaagcca tttttccggt tcttttgttc
    90241 ctagacgtcc aatagcccaa gctgctgttc ctctgatgac agggcggaca tctgttaaac
    90301 attctgaaat ctcaggcaat gccgttcgat cacctagatt agctaaagca atcaatgcgt
    90361 ttctctgcaa aggtttcttc ccacgccatg aaccagctaa atgcccaaat tgctgtttga
    90421 agtctttatt agacatcgaa agcattggct ttaattttgg atatatttcg tctacttttg
    90481 gttccatctc ttcatgaaaa tgaaaatctt ttccttgatt gtaagggcag actaactggc
    90541 agatatcaca tccataaatg acatttcgca tttttttacg atattcttcc ggcatcatcc
    90601 cttttgtctg agtttgataa gacaaacatc gctgggcatt cattcttccg tcaccaagca
    90661 atgcttttgt cggacaagca gtcacgcagc gcatacagtc accgcaacca aattctcctg
    90721 gtttatcagg ctcaaataca atattagtaa cgatctcacc aagatagaca aatgaaccga
    90781 actcttcagt gatcaacaat ccgtttcgtc caataaatcc taaaccagct cgctgtgcta
    90841 cagcgacatc gatcagttct ccagtatcta cttgcggagc tagacgccat tcctcttctt
    90901 tttgccattt ttctgctctt gtttggatga attcgatcaa tcggttcaaa cggtctctga
    90961 gtatatcatg gtaatcgatc ccccaagaag cacgagcaaa ctgcccgcgt ttttcatccc
    91021 taggcacttc ttcatggatc ctagtaggat acgcaagtgc aatggaaatg atcgatttcg
    91081 gctgatcaaa tgtcatttct ggataaagac gctcatcgat atttggatgt tcaaagccag
    91141 aagtatggcc agctgctttt tgttcttcca acgattcttt taatgaatca aaaggttccg
    91201 ccgtggtgaa cccgattttg tcaattccta atcgtttgct ttcttgtatg atttcttctt
    91261 ttaatgtcat ggtcttcctc gcttgctgtt aacggctgta taacccataa tatagttttt
    91321 cttttttcag ctggacaaac tggatctgct gatcggcaat cttcttttct tccatccatt
    91381 tttttcttgc agcaaatact tcccaataat ttgttgaaat taattttctt ttgttatcta
    91441 atgcattaaa aaaattcaat gaaactggtt ttgtacttaa cagttcatgg agccttacct
    91501 cttcccatgg cgaaaactca gacagatcgc gggaatacaa tacttcttca tagagatttt
    91561 tttgctgtgt gtacgtgaat gtttgcggga ttttcccagg cctagcaatt tctactagac
    91621 gattataaaa catattcatt aatttgctgt tggcaataaa ttgactttta taataggccg
    91681 actggatctt tttgattact ccttctgctt tgatgactga aaataatgca ggccatgctt
    91741 tgacggttat ttcgtcgttt tgtttaacta atacgccagg tgtgaagccg actggagaaa
    91801 ggaacacaaa ataaccgata ccggtatttt catctaaagg ctgaaattca tcaaacaacc
    91861 atttgcctat gtacagctct tcatctggtt ctgttgtctc attttgattt gctatgaata
    91921 atttagctaa ttctgcttca agaaattgaa ggtcttgatc cttgtcggta ttttcctgct
    91981 ggctgatcaa tcgaaagact tcttctttaa tcgtatattt atctttacgt gtaaaattca
    92041 tagccacacc ttccttcctt actctaacta taacggaatt tcttcaaaaa aggtatctgt
    92101 acgacgaaaa acagcataat tttttttcat atctcttata aaaaatgcaa ggtctgctcc
    92161 tcaagctaga ccttgcactt ttcagctttc ttttgtttgt gacaaacctt catggatcgt
    92221 ttcaatattc catttcatca tctgatagta agaatctcct tgttctcctt cttttgctat
    92281 ggaatcagtg aacagtttat catagatttt caaacccgtt tcttttgcta cccgttccat
    92341 gcttcttgag tctacactgg tttccacgaa taaaaccggt acttcttttg ctcttatctg
    92401 atcaatgatc gctttcattt gatcaggcgt accttgactt tctgtattga tctcccatat
    92461 ataagctgct ggcaaatcat atgctcgtga aaaatacttg aatgcccctt cacttgttac
    92521 taataatttt ttgttctctt cgatagaagc aaaactttcc ttcgcttgtg tatctaattc
    92581 ttttagtttt tccacatatg cttctgcatt ttttttatag agtgtcgcat tttctgcatc
    92641 tttttcagag aatatacgtg cgatttcctc cacatatttt attccgttag ataggtctag
    92701 ccaagcatgg ggatctgctt ttgtatgttc ttcaccgcta gttaaataaa gaggttctac
    92761 atttttgcta actgcaaaat aatcttttcc ttcttctttt ttagccgttt ccatcaagtt
    92821 atcgaaccag ctgttacctg tttcaagatt caaaccgttg tataaaataa catctgcatc
    92881 gcttgccttt ttgatgtctt ctggtagtac ttcatattca tgcggatctg ttccgactgg
    92941 tacgatactg tggatatcta tttgatctgt tccgacctct tttgccatgt ccgccaagat
    93001 cgaattggta gccacgactg acaacttttc tttacttcct tcatccgctt ggtcagaagc
    93061 ctgctttccg caaccggcta ataccaagaa actaactgcc aagattaaaa agagtgattt
    93121 ttttgttttc atctatctgc ttcctttctg aaataaaatt ccttttgttg gagaaaataa
    93181 aaaagcaagg ataaaaaatg cggtacatgc taacacgatc gtagctcctg atggccaatt
    93241 gtaactataa ctgaaaaaca caccgacaac tgcacttagc ataccgattc ctgcagctgt
    93301 aatgatcatt ttcagtaaat ggttcgttag caagtaagcc gtggcggctg gtgtgatcaa
    93361 catggcaatc accaagattg ttcctactgt ctgtaaactg actacagcca ctaatgtcaa
    93421 aaagaacatc aaaagataat ggatcagcga tgtgttcagc ccataagctt ttgccattgt
    93481 cggatcgaat gatgtgatct tcaattcttt ataaaagaaa aagacaaata tcaagacgat
    93541 tccactaacg agtgctgtca gcaacaaatc gctttcccta acagctaaga cattcccaaa
    93601 taaaatatga tacaaatctg tcgcactctg ggcatatgaa atcaagataa tccctaatgc
    93661 aaaaaaggag ctaaagacaa ttccaatcgc tgtatcattt ttcaatcggc tccgctgagt
    93721 cacgaaacca atcactgctg ctgttagcat cccaaaagca gtggctccaa agatgtaact
    93781 aaaaccaaac atataagaaa tggctacacc tggaagaact gcgtgagaga tagcgtctcc
    93841 catcaaagac atccctcgta aaataataaa agaaccgatg actccagaag caagtcctac
    93901 aagcatggaa gtgaccaaag cgtattgcag gaattgataa ttcattaatc catcaataaa
    93961 ggattggatc attttttctc tcctcctttt actaaatgtc tgatgatctc accataggcc
    94021 aattgaaggt tcttcgatgt aaagacttct tgtactggac cggaagcgat cagctgttta
    94081 tttaaaagaa taacctcatc gaaatattct tctactttat gaagatcatg atggacgatc
    94141 aaaatcgttt ttcctgaatt cttcaattcc tgcaagatgt caaagatctt tcgttcactt
    94201 aacgcatcaa tccctacgaa tggttcatct aaaaagatcc attctgctcc ttgggctaga
    94261 gctcttgcaa taaaaactct ctgaagctgt ccacccgata gttcgctgat ctgtcttttg
    94321 gcatattctt ccatccctac ttttttcaaa gcttgtcttg cacgttcttt ttcttttttc
    94381 ccaggtcttt gtccaattcg taaagatgga tatgttccta aaagtacaac gcctaataca
    94441 tcaattggaa aggaaagatc caattcactt cgctgttcca cgtaggctat ttttttacgg
    94501 actgagttta ccgactgtcc agaaaaggtg actttaccag tagtagctgg tatcaactct
    94561 agcaaagatt tcataaatgt tgattttcct gcaccgtttg gtccgataat accggtaatt
    94621 ttttgtggat ttatcgtcaa gttgatagtt ttcaaaacag ttttcccttg ataagcggct
    94681 gaaaggtctt gaattacaat ggccgtacgt tccaaatctt acactccttt ttaggtttac
    94741 ctaacttttt atttaaatat agtttaacta aaatggaaag cattttcaag tagaatgatg
    94801 aaaaagtttt tttcgaattt tcctcgcatt ttatgaaaat tttctgtaga atcacatcaa
    94861 gagttcaata aggctaacct aataatgaaa aacatgtgtt gaaacgtttg attatttttt
    94921 cttgttgact caacaacgaa aggagttttt gtatggaaga agaaaagtta actcgaagtc
    94981 ttagtgcccg tcatatccaa atgatcgcac taggtggaac gatcggtgtc ggtctgttta
    95041 tgggtgcctc ctcaaccata cgttggacag ggccctcagt gatgggagcc tatgcgattg
    95101 caggattctt tttgtatttg attatgcgtg ctttaggcga aatgctttac gttgatcctt
    95161 cgactggttc ttttgcaaat tacgcgagcg agtacatcca tcctgtggct ggctacttga
    95221 ccgcttggag taatattttt caatatattg tcgtaggaat aagtgaagtg attgctgtag
    95281 gatcttatat gaattattgg tggcctgatt tgccggcaat tattcccgga atcattgtcg
    95341 tcttgtttct tatgctggca aatcttattt ctgtcaaggc gtttggcgaa ttagaatttt
    95401 ggttttcgat catcaaagtc ataacgatca ttttgatgat cattgcaggt cttggggtaa
    95461 tcttatttgg atttggtaat catggtcagg cagtagggat ttcaaatctt tggaaaaatg
    95521 gtggattctt cactggaggc gtcaaaggat ttttctttgc attatcgatc gttgttgctt
    95581 cctatcaagg aatcgaactg atcggaatga ctgctggtga agcagagaat cctaaaaaga
    95641 cgatcattga agctgtccag tccactatcg gtcgaatctt gattttttat attggtgcta
    95701 tttttatcat tgtgagtatc tatccgtgga atcaattgag tgagattggt tcaccttttg
    95761 tacaaacttt ttctaaagtc ggcattacat ttgctgcagg actgattaat tttgtcgtga
    95821 ttacagcggc attatcaggt tgcaattcag ggattttcag cgcaagtcgt atggtctata
    95881 cacttgccat aaatggaaag atgtctaaaa aatttctgaa actatctcgt cacggtgcgc
    95941 ctttttatcc tgtcgtagca atctcaggtg gaatcttaat tggtctgatc ttaaattatc
    96001 ttctaccaat gttcatcaac cagtcagaaa atattttcgt tttcgtatac agctcaagta
    96061 ttttgcctgg tatggttcct tgggtagtga ttttgatcag cgagattcgc ttcaaaaaga
    96121 agcacgcaga taaaatgcat gatcatcctt ttaaaatgcc actatctcct tatacgaatt
    96181 atgtgacact tgctttttta gctatcgtat tgattttcat gtttatcaat cctgaaacga
    96241 gaatctcatt gattattgga ctcgttttct tgctttacat gacgatccat tactttgtac
    96301 gcgaaaaaag aaccggaaaa taaaaaaaga acgaagcttc accttagtgg aagcttcgtt
    96361 cttttttatt gcttttatca attcaatttt agcgtctcac cgggagtcag gaaataattc
    96421 tccatgctca tcccattcag cgacaagatc gtttctactg gtacgccagt tcgttcggct
    96481 atttgatttg gaccttctcc ttccaaaact acggttgtcg cagcctgtga agtcgcgctg
    96541 ttggtattag tttcagagga atctgttgtg tcttgtgttg ttcgagcttg catttcagaa
    96601 gcttctaccg actctgctgt ctcagaatca gaagatgttg tgtcttgtgt gcttgttgac
    96661 tctgcttgaa gagaggcgct agtctgcaaa taaatatcgg aaatcttagc gacatgattc
    96721 gtataattag ccgataattg attgatcaaa gtatctaagt ctacaccgtc tttattttct
    96781 gctgcctgat acgctgcacg taattttctg atcccttcgt cggagattgc ttgaagctca
    96841 cgtgcttttt ggttagcaac tgctgataaa ccagctattc cctcttgatt tccctgaatt
    96901 tctgtctggt attcttcaat caatgcaggc gtcttttctt cgatcttttt cgaataatca
    96961 tttacgattg cttgaagttg ctctggcaaa ccatttgctg ttttttcttc agaagtttgt
    97021 gtctcttttg ttttagttga tgactcactt gtttgtttcg tctctgtttt ctttgtcgtt
    97081 gtttccgtta tggtcgtact tttcgcttct gacgaatttt ttccatgaaa atatagaccc
    97141 gcaactcctc ctgctatgat caaaaacacg gcaactgctg ccccaatcat gatcatccgc
    97201 ttacgagctg cctgtttttg ctgtcttctt cgggtcatcc gaacattttc tccccactca
    97261 ttttcatcat acattttttt caccaccaat ttttatgtat aatagcgtta tcaaacgctt
    97321 catattctta ttgtagcaaa taattgtcgc tgtgcacatt tttatctttg ttatttataa
    97381 gaaaatttca ccagttgaga tgattccaag attgtccgtc gatttctcct tgcagctgca
    97441 ttgttcgttc gtctatctca gccatcagtt tctttatttc atataagagc gcacggtctt
    97501 gatattctga tttttcgctt aattcatcta attgttggat cagccaatca tttgtcataa
    97561 tgaagttcct ttcatttctt gcagtgtaaa ggtcaagtct tcgatctgct cttttgcctc
    97621 agtcagtgct tctacgatat atgcttgttt ttcagattct tcttcctgca ttttctgatt
    97681 ttcctgtact ctttgaataa accagtcaat ccgctgagtc agcgatggtt tgccttccaa
    97741 tgagagatac tgctgataag caattagctt ctcccaacgt ttttcctggg ataaatacat
    97801 aaattgtgct aaaacgaatg gcggaagata ggtcatatgg aatttatttg cgattcgctg
    97861 atacggcctc aaaaattcgg aaatcgtata ttcttctttt cctccagctt ggtattcttt
    97921 ttccgccaca cctgttgtca atacgattcc tagttctttc ccttttaata catgtgctgc
    97981 tcgttccaag acattatctt gccaaatttt taaatgagca ggagaactat accagtaaaa
    98041 cggaaactgg aaaatgatcc gatcatgctg ggccaagagc tgtagttcag tctctatatc
    98101 tatttttccg tctggataac ttgattccaa atgatgccaa gtagctggta aaccagcaga
    98161 agcttctttg aaaaattgct gatttaaaga ttcttcgatc gttggatggc taatgatgat
    98221 aagtgtacgc atcccttttc ctccttttta gtcttcgctt tacagtgtag cataaccgcc
    98281 acaagtttct tttgccgatg cttgtcattt taaccagact aatcaggttg tccaagaaac
    98341 tgcggtttgt ttttccaact gttttttcaa ggtatccaaa gcaatattct taaaattttc
    98401 gtttttcata cgtttacgat agttcgtagc cgtttctccg gtactctttt tgaacattcg
    98461 gctaaatacg actagactat tgaaccctac ttgataggca atactttcca cggattcatc
    98521 cgtcagagaa agaagaaacg cccctcgatt gatccgtacc ccgatcaaat attccttgat
    98581 actggtaccc atatgatttt tgaatactcg cgacaaatgg ctccgattga ccgctaaatg
    98641 ctgggcgatt tcctcaacag acaatttttc agcataatgt gcctcgatgt atttgactgt
    98701 ttcaacagct aaagaggaat gaaccttttg tacaccaccg ctgacctttc cgccatcttt
    98761 taaaaggact gataaaaaac ggtaggttaa tgctgttaac tgtaattcat tttccaaggt
    98821 ttcttccgta tctttcatgc attctaaaat aatgtcgata tatttttgta tgtcagaaga
    98881 gaccatcgtg tattggtctt ctctgaaaag cgactgccga atgatttctt ctgcagcact
    98941 cccaccaaat gaaagccagc aatacatcca cggatcttct ccatctgata agtaaaacgt
    99001 cgagtctcct ggacgaatca agaacagatc accttttttc aattggaatt gttgattttt
    99061 cacatgataa gatcctttgc cttccatcac gacatgcagg atgtaatcat tgcgaatagc
    99121 aggaccaaaa gaatgaaacg gcatcgtttt agagaaacca caaaaatcaa aatacaattc
    99181 tttttctact tgttgatgtt ccttttttaa aaaaatcgat tgctccacgt ctatccctcc
    99241 ttactccttt agtataatgc aacaaaaagt taaataaaag tcacagaaat atattaaaaa
    99301 ggaagcgatt tcttgttaag tttaagtcat taaaagatct ttgttattcg ttgtaaccgg
    99361 tttacttagt attatatatt gaacaggaga ggaatacaga ttatgaaaag caaaatgatc
    99421 caacgtgtgt cctacgcttt aggcgctttt ggacacgaca cattctatgt tacattaagc
    99481 acttatttta tggtattcgt gacaagccag atgttcgcag gaacagataa ggcaacgaat
    99541 gcaaaaatga ttgctacagt tacaagctta gttgtaggta tccgcttagt tgaaattatt
    99601 tttgatcctt tgattggtgg catcatcgat aatactcgta caaaatacgg taaattcaaa
    99661 ccatggttag ttatcggcgg cgttgttagt tccgtactct tggtagcaat ctttaccaat
    99721 ttctttggct tagctactca taatacgact ttatttatca tattatttgc aatcgttttc
    99781 atcttattgg atagttttta ttcatttaag gatatcgctt tttggtcaat gattccagct
    99841 ttgagtacgg aaacaaagga acgtgaaaaa tttgctacgt ttgctcgttt cggctcttct
    99901 ctaggtgcaa atggtactac tctagtcgtt gtccctatcg ttactttctt tacctatctt
    99961 gttactcata aacatattga aggcgcttca ggctggttct ggttcggtgt gattgctgct
   100021 gttatttcag gcggtactgc gattatcact gccttgggca caaaagaagt cgatactgcg
   100081 atccgtcagc aaaatgaaaa agctgggatc aaagatgtgt tcaaagcagt tgctcaaaat
   100141 gatcagttga tgtggcttgc ccttgcttat atcgcttatg cgattgccaa tgcagcaaca
   100201 actgccgtat tattctactt cttcaaatat gtacttggcc aaccaactga attttggatc
   100261 gttggtctag ttgctgcctt acttggttta gtagctgttc cactattccc aatgcttaca
   100321 cgcgtcatct ctcgtcgcta cgtttacctt ggagggatcg caatgatgat ttcttcttac
   100381 tttttcttta cgatcgcagg ttcaagtttg ccaatcgtta tcatcgggct agtattgttc
   100441 tacttccctc aacaattgat tttcttatcc gctttgatga cgatcacaga ctctgttgaa
   100501 tatggtcaat ggaaaaatgg tatccgtaac gaagctgtta ctctatcaat tcgcccttta
   100561 ctagataaaa tcgctggtgc tttgtctaac gggatcgtag ggtttgtcgc tatcgcttct
   100621 gggatgactg gtaatgctac tgctgctgat atcactgctc atggcgtaac gactttcaaa
   100681 gcttatgcat tctatgctcc tgctgctttg atgattttct ccgctattat ttttgcttgg
   100741 aagattacat tgacagagaa aaaacatgca caaatcgttg agaaattgga aaacaaattg
   100801 gctccagctg atacaatgga agatgaactt cacgatgcag tagatccttc ccattaagaa
   100861 aggatcttga aaatgaagat tacagaaaaa gattttggcc aaggttatca cttgataacc
   100921 ttggagaaca aaaacaagct agcactttct atctctgatt taggtgctag aatcgtcagt
   100981 ttaaaatcaa atgatcgaga attagttttg ggatttgaca ccgctgaaga atatatcgaa
   101041 aaagatccgt atatcggtgc ttctatcggt cgcaccgcag ggagaatcga aaatggccgc
   101101 ttttctctca atggaaaaac ttaccaatta gccacagatc caaaaactgg acataatctg
   101161 catggtggtg ctcctggatt tgaattaaaa aaatggtctt atgtcatttt gaatggcgaa
   101221 aatgaagctt ctgtcatttt tactactaca agtcccgacg gagaacatgg ttttccaggt
   101281 acaatggatg tggaaatccg ctatactttg acaaaagata atatctggcg agtgacctct
   101341 cgcggcacca gtgaccaaga tactttattc aatccgacaa atcatgttta cttcaacttg
   101401 acgggagatg cttctcagtc aatcgatcaa catgagcttt ggctcaatag cgaagcttat
   101461 gctcctttgc gaacagatag tattcctata ggggtaaaag aaaatgctgc aggaagtgct
   101521 ttcgattttc aaatacctaa aaaattagcg tccgtttttg ctagtgattt ggatcaaaaa
   101581 aatcttgttg acggaatcga tcatccattt ttcttaaaag aaaccggctt gggtaaagaa
   101641 gccgctcgct tgactagccc cgataaaaga atccaagtag atattgctac agatgcttct
   101701 agtgtggtta ttttcactgc aaatttcggc acagaaacac cagaaatgcg caaccgaaaa
   101761 ctggcacatc acggtggcat cacatttgag actcaaacag ctccaggtgc agagcgcttc
   101821 tcagcatttg gttcgattca tttaaaagcc ggatcagtat ttgaaacagt aacagaattc
   101881 aaaatcaaaa caagaaagga ataactcatc atggaaatca aaagaagctt aaacacaaaa
   101941 tttgccgaaa cattcggacc taaaaaaact acacaatact tctcaccagg acgcatcaat
   102001 ttgattggtg aacacacaga ttacaatgga ggccatgtct tccccgcttc catcacttat
   102061 ggaacgcaag gtgtagcagc acctcgagac gataataaaa tattagttta ttccacaaac
   102121 tttgacgata tcggtgtcat tagttttact ttagatgagc tagaatatga taaaaaagca
   102181 aactgggcaa attacgtaaa aggaatggtc cttaaattaa aagaagctgg acactcaatc
   102241 gatcatgggt ttgagttatt agtggaagga acaatcccta atggtgcagg actttccagt
   102301 agcgcttcat tagaattatt agtaggtgtt gtattagaag atctgtttga tttaaaaaca
   102361 gatcgcttgg aactagtcca aacaggtaaa aaagtagaaa atgaattcat cggtgtcaat
   102421 tcaggtatca tggatcagtt tgccatcggc ttcggtgagc tagatcatgc aatcttatta
   102481 gatacaaata cgctgaaata cgaaatggtt ccagtgaaac tagatggtta tgcaatcgtc
   102541 atcatgaata cgaataagcg gcgggaattg gcagattcaa aatacaatga acgccgtagc
   102601 gaatgcgaag aagccttggc acgtttgcaa aaaactttgc ctatctcttc tttaggagac
   102661 ttagatgaag aagaatttga atcaactatt gaccaaatcg gcgatgatac attgatacgc
   102721 agagctcgcc atgccgtttc tgaaaatcag cggactttga aggcaaaagc tgaattagaa
   102781 gctgggaact tagaagcatt tggtcaactg ttaaatgatt ctcaccactc tcttcgctat
   102841 gattatgaag taactgggat cgaattagat acactagtag atgctgctca aaaacaagaa
   102901 ggtgtcttag gtgcacgaat gacaggagct ggatttggtg gctgtgcgat tgctcttgtc
   102961 aaagaagaaa atatacctgc cttcaaaaac aatgtctatg atgaatacat gaaagttgtc
   103021 ggctatgctc cggaatttta tgttgcacac attggaaatg ggacaacaaa gatcgatcca
   103081 gaagctgttc atgtttgata aaaaaatcaa cgatctcagc taaaaacaaa tagataaaaa
   103141 taacctctca gcaatttcca aatgtgagcc ttttgctcgt atttgaaaat tgctgttttt
   103201 tattgacacg gaaagagaac gtgtgttcta attgtgttga agaggtgatt gttatgtggg
   103261 cgaatcaaaa tccggtattt gtttatgaaa aagaaccttc aagagatatt ttatgtattg
   103321 actgcaaatc tttttacgcc tccgtagagt gcgttgaaaa ggatcttgat ccccttacaa
   103381 ctaaattagt agtcatgtcc tatccgtccg attcgacaga aacacggggt agcggattaa
   103441 tcttggcttc cagtcctgca gcaaaaaaag cttacggcat caccaatatc agccgtgcca
   103501 gagatcttcc cttcccctat ccaagtgatt tatatattgt tgccccaagg atggcctatt
   103561 atatggaaaa gaacagagaa atcaattcta tctataaaaa atatgcagac gaagcgaacc
   103621 atcatgtcta ttccgtcgat gaaagcttcc ttgatgtaac aaatagcatg gcactctttg
   103681 gtaaaacaaa tgcgtacgac atggctaaac tgatccataa agatgtgttt gagcagaccg
   103741 gaatctacac gactatagga attggcgata acccgctact tgctaaacta gccttagaca
   103801 atggctcaaa agacggaaag caaatgtttg ctgaatggcg ttatgaagat gtaccagaaa
   103861 agttatggaa aatctcagat atcactgact tttggggaat cggcaaacga acagcaaaac
   103921 gtctgaaaca aatgggtata cattctgttt atgatttagc tcacgcggat tattatcact
   103981 tgaaaagcaa gctaggggtc atcggtactc agctttatgc ccatgcttgg ggcatcgatc
   104041 gaagtttttt gggacaagaa tatacaccaa aatcaaaaag tatcggaaat agtcaaatcc
   104101 tagatagaga ttatacaaga cgagaagaaa tcgagatcgt tatcaaagaa atggccgacc
   104161 aagtcggcac tcgcttgaga cgatctgcag caaaaacaca agtagtcagc ttatgggtag
   104221 gatactcttt aggctatctt gatccaaatg gcaagaccga gtttcaccag caaatgaaaa
   104281 tcgaagcgac aaatgctagc agagatctag cagatgcttt attgaccatt ttccaccagc
   104341 attaccacta ccaggatatt cggcgtgtag gcgtgaactg ttccgacctc gtatacgcga
   104401 caggtttaca gcttaacctt tttgaagatc ctgaaaagca gataaatgaa gcgaaagttg
   104461 attttgttgt cgatacgatt agaaaaaaat acggctttca atcaatcatc catgcgcata
   104521 gtctcttgca aggaggacgc gccatcgcac gtagttctct cgttggcggg catgcaggtg
   104581 gtatgagtgg attagaaggt ggaaaagatg agacggacag caaaaaaatt cattgactat
   104641 aacgagtatc gagatcggcc atttggatta aaatggggga ctgcttttgc gatggaagaa
   104701 ctagtcaacg gtatcaaaaa aatgaagaag aagcacgcaa acagcctctt cctaaacaac
   104761 aaatgacatt gcaagaaatc gatagtatac tgacagaagc ctttttatct cgtaaagcag
   104821 taatcattca gctcaattta aaagatgaat ttggaagact cttggatgag gtcgaagggc
   104881 acttcattgg tgaagcctat gaagattact ttatgattga ccatcagccg atattgtggg
   104941 aagacgtacg gtatattgag ttaaaggaaa caaaaaaatg gtttgtgaca tgagaggttg
   105001 tgacagaagt gatcaacttc aaaaaataag aaaggatttt tcgaaaattg cttcttaaat
   105061 ttttgtggaa ttttggctta tttttcgaag aagcaacttc tggaacaacg tatattagat
   105121 atcagaggtt gtgaaaaagt cgcttagttt tgagtaacaa gccaaggcgc tgatttcaca
   105181 acctctgtct atctatccat ctattcggta agattcatgc atgacgtctt ctttatttag
   105241 tatgtagagc cctttttctt ctgaccattc aacataaatc agctgtttta catctgcata
   105301 gccttctttc ttcaagttct ccataagcca tgcttcagtc aattgattgg actgaagcac
   105361 tttatgctga atttgccctt catctacaag caggatcgat aaagctttgt cttcatctga
   105421 ttttttcaat acactcattt gaccggcatt ctctaggata acatgtttgg cattttcaag
   105481 aaaaaagcat tcttgctgtc ttaagattgc tcgcaactgc tccatctcga tatggttatt
   105541 tgtcaactct gtcatgttga tgacgccgtc tttgattaga acagatggct cgcctttgac
   105601 ccaacgattg accttttcat ttttttggac gatacgttcg ataccataaa tcattactgc
   105661 ccaaagcgca atggcaaata ggacatgccc tacatggaca ttgtcatcat aggttgattc
   105721 ttctaagatc ccacctaaaa caagcgtata gactaaatca aacggtgtga tttctgacat
   105781 ggatttcttc ccaagcaaac gtaccactaa taataaaccg atcaacccga acaccagttt
   105841 cattgtaatt gaaaaaatca ttttttctcc ccctaactat ctgttaatta aattatatat
   105901 gctttctcac gaacacgcat ggaatataca aggaagaaat gtatcctttt actaaaaaaa
   105961 ggactgtgac actgtagtga cccccaaaag ttagactttt ttggagtgga gaaatccact
   106021 cctttttttt atgctctaaa atgatatttt tacacaaccg ttacggttgt tttacgaaat
   106081 tggacg
//
LOCUS       DAPBAF010000003        97631 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.003, whole genome shotgun sequence.
ACCESSION   DAPBAF010000003 DAPBAF010000000
VERSION     DAPBAF010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 97631)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 97631)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..97631
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.003"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(99..1229)
                     /locus_tag="RD451_000224"
     CDS             complement(99..1229)
                     /locus_tag="RD451_000224"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HDT7565522.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     misc_binding    complement(1289..1516)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(1788..2861)
                     /locus_tag="RD451_000225"
     CDS             complement(1788..2861)
                     /locus_tag="RD451_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDT7565523.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRK"
     gene            complement(2858..3685)
                     /locus_tag="RD451_000226"
     CDS             complement(2858..3685)
                     /locus_tag="RD451_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7565524.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            complement(3686..4492)
                     /locus_tag="RD451_000227"
     CDS             complement(3686..4492)
                     /locus_tag="RD451_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7565525.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            complement(4504..5589)
                     /locus_tag="RD451_000228"
     CDS             complement(4504..5589)
                     /locus_tag="RD451_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7565526.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            complement(5606..6148)
                     /locus_tag="RD451_000229"
     CDS             complement(5606..6148)
                     /locus_tag="RD451_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7565527.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            6406..7395
                     /locus_tag="RD451_000230"
     CDS             6406..7395
                     /locus_tag="RD451_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HDT7565528.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIIAFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            7392..8129
                     /locus_tag="RD451_000231"
     CDS             7392..8129
                     /locus_tag="RD451_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HDT7565529.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            8126..8677
                     /gene="coaC"
                     /locus_tag="RD451_000232"
     CDS             8126..8677
                     /gene="coaC"
                     /locus_tag="RD451_000232"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HDT7565530.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            8693..9325
                     /locus_tag="RD451_000233"
     CDS             8693..9325
                     /locus_tag="RD451_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDT7565531.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            9410..10057
                     /locus_tag="RD451_000234"
     CDS             9410..10057
                     /locus_tag="RD451_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDT7565532.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            10062..11045
                     /locus_tag="RD451_000235"
     CDS             10062..11045
                     /locus_tag="RD451_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HDT7565533.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
     gene            complement(11448..12962)
                     /locus_tag="RD451_000236"
     CDS             complement(11448..12962)
                     /locus_tag="RD451_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HDT7565534.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            13100..13906
                     /locus_tag="RD451_000237"
     CDS             13100..13906
                     /locus_tag="RD451_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565535.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            complement(14081..14650)
                     /locus_tag="RD451_000238"
     CDS             complement(14081..14650)
                     /locus_tag="RD451_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7565536.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(14733..16793)
                     /locus_tag="RD451_000239"
     CDS             complement(14733..16793)
                     /locus_tag="RD451_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HDT7565537.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            complement(17070..18548)
                     /locus_tag="RD451_000240"
     CDS             complement(17070..18548)
                     /locus_tag="RD451_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7565538.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
     gene            complement(18846..19781)
                     /gene="murB"
                     /locus_tag="RD451_000241"
     CDS             complement(18846..19781)
                     /gene="murB"
                     /locus_tag="RD451_000241"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HDT7565539.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            complement(19854..20774)
                     /locus_tag="RD451_000242"
     CDS             complement(19854..20774)
                     /locus_tag="RD451_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDT7565540.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            20887..21639
                     /gene="xth"
                     /locus_tag="RD451_000243"
     CDS             20887..21639
                     /gene="xth"
                     /locus_tag="RD451_000243"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HDT7565541.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            22503..23036
                     /locus_tag="RD451_000244"
     CDS             22503..23036
                     /locus_tag="RD451_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HDT7565542.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
     gene            complement(23526..24050)
                     /locus_tag="RD451_000245"
     CDS             complement(23526..24050)
                     /locus_tag="RD451_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7565543.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(24043..24516)
                     /gene="tsaE"
                     /locus_tag="RD451_000246"
     CDS             complement(24043..24516)
                     /gene="tsaE"
                     /locus_tag="RD451_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HDT7565544.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(24639..25619)
                     /gene="pta"
                     /locus_tag="RD451_000247"
     CDS             complement(24639..25619)
                     /gene="pta"
                     /locus_tag="RD451_000247"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HDT7565545.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(25772..26452)
                     /locus_tag="RD451_000248"
     CDS             complement(25772..26452)
                     /locus_tag="RD451_000248"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HDT7565546.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            26578..27447
                     /locus_tag="RD451_000249"
     CDS             26578..27447
                     /locus_tag="RD451_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDT7565547.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            27473..27988
                     /locus_tag="RD451_000250"
     CDS             27473..27988
                     /locus_tag="RD451_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565548.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(28035..28628)
                     /locus_tag="RD451_000251"
     CDS             complement(28035..28628)
                     /locus_tag="RD451_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7565549.1"
                     /translation="MLEWRKGEETMIRFARKEDAPEIAPLILVILKDMELPFLKQTGE
                     QKTLEILEEAITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKY
                     QLDASTRLFIDKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLS
                     VDEKNPKAKKLYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(28653..28832)
                     /locus_tag="RD451_000252"
     CDS             complement(28653..28832)
                     /locus_tag="RD451_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565550.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(28909..29418)
                     /locus_tag="RD451_000253"
     CDS             complement(28909..29418)
                     /locus_tag="RD451_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565551.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(29514..29894)
                     /locus_tag="RD451_000254"
     CDS             complement(29514..29894)
                     /locus_tag="RD451_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDT7565552.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            30224..30973
                     /locus_tag="RD451_000255"
     CDS             30224..30973
                     /locus_tag="RD451_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HDT7565553.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(31157..32434)
                     /locus_tag="RD451_000256"
     CDS             complement(31157..32434)
                     /locus_tag="RD451_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565554.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(32513..33157)
                     /gene="pcp"
                     /locus_tag="RD451_000257"
     CDS             complement(32513..33157)
                     /gene="pcp"
                     /locus_tag="RD451_000257"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HDT7565555.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(33356..34300)
                     /locus_tag="RD451_000258"
     CDS             complement(33356..34300)
                     /locus_tag="RD451_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HDT7565556.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(34302..34988)
                     /locus_tag="RD451_000259"
     CDS             complement(34302..34988)
                     /locus_tag="RD451_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HDT7565557.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            35462..35782
                     /locus_tag="RD451_000260"
     CDS             35462..35782
                     /locus_tag="RD451_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HDT7565558.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            35936..36841
                     /locus_tag="RD451_000261"
     CDS             35936..36841
                     /locus_tag="RD451_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDT7565559.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            36838..37611
                     /locus_tag="RD451_000262"
     CDS             36838..37611
                     /locus_tag="RD451_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HDT7565560.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(37792..39216)
                     /locus_tag="RD451_000263"
     CDS             complement(37792..39216)
                     /locus_tag="RD451_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDT7565561.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            39427..39873
                     /gene="nrdI"
                     /locus_tag="RD451_000264"
     CDS             39427..39873
                     /gene="nrdI"
                     /locus_tag="RD451_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HDT7565562.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            complement(39938..41920)
                     /locus_tag="RD451_000265"
     CDS             complement(39938..41920)
                     /locus_tag="RD451_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDT7565563.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(41934..42830)
                     /gene="murQ"
                     /locus_tag="RD451_000266"
     CDS             complement(41934..42830)
                     /gene="murQ"
                     /locus_tag="RD451_000266"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HDT7565564.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            complement(42833..43894)
                     /locus_tag="RD451_000267"
     CDS             complement(42833..43894)
                     /locus_tag="RD451_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HDT7565565.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            complement(44105..44671)
                     /locus_tag="RD451_000268"
     CDS             complement(44105..44671)
                     /locus_tag="RD451_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HDT7565566.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
     gene            complement(44699..46201)
                     /gene="eat(A)"
                     /locus_tag="RD451_000269"
     CDS             complement(44699..46201)
                     /gene="eat(A)"
                     /locus_tag="RD451_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HDT7565567.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            complement(46459..47580)
                     /locus_tag="RD451_000270"
     CDS             complement(46459..47580)
                     /locus_tag="RD451_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HDT7565568.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            47706..48647
                     /locus_tag="RD451_000271"
     CDS             47706..48647
                     /locus_tag="RD451_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HDT7565569.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(48797..49693)
                     /locus_tag="RD451_000272"
     CDS             complement(48797..49693)
                     /locus_tag="RD451_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HDT7565570.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            49962..51302
                     /locus_tag="RD451_000273"
     CDS             49962..51302
                     /locus_tag="RD451_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDT7565571.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            51520..51963
                     /locus_tag="RD451_000274"
     CDS             51520..51963
                     /locus_tag="RD451_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HDT7565572.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(52467..53885)
                     /gene="nhaC"
                     /locus_tag="RD451_000275"
     CDS             complement(52467..53885)
                     /gene="nhaC"
                     /locus_tag="RD451_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HDT7565573.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPNLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(54288..55511)
                     /locus_tag="RD451_000276"
     CDS             complement(54288..55511)
                     /locus_tag="RD451_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDT7565574.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKERFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(55542..56381)
                     /locus_tag="RD451_000277"
     CDS             complement(55542..56381)
                     /locus_tag="RD451_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HDT7565575.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETIVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNVALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDENNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(56398..57078)
                     /locus_tag="RD451_000278"
     CDS             complement(56398..57078)
                     /locus_tag="RD451_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7565576.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(57080..58153)
                     /locus_tag="RD451_000279"
     CDS             complement(57080..58153)
                     /locus_tag="RD451_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDT7565577.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IVEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRKKALDYLIKS
                     GVKINILQKNDLDSRIKVIEGGR"
     misc_binding    complement(58209..58447)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    complement(58490..58723)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(58800..59471)
                     /locus_tag="RD451_000280"
     CDS             complement(58800..59471)
                     /locus_tag="RD451_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HDT7565578.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYLDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLN
                     KKTEK"
     gene            complement(59558..62236)
                     /gene="mgtA"
                     /locus_tag="RD451_000281"
     CDS             complement(59558..62236)
                     /gene="mgtA"
                     /locus_tag="RD451_000281"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HDT7565579.1"
                     /translation="MSFGHKGEIEMEKKKDTQKIYAAFAGKTKQELFELFHASANGLT
                     EEQIERSRENYGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPG
                     DKDLFGVAIIFTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEE
                     IVCGDLVRLSAGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSY
                     ENLVFMGSNVISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKF
                     MSLMAPAVIVINGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGT
                     VIKNLNAIQNFGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQT
                     GLKNLLDVAIIDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGA
                     IEEMLNISKFIDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFS
                     VKDESDMVLIGYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLE
                     INELVTGEKISEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGIN
                     DAPAMKVADIGISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKAT
                     ASSNFGNMFSVLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKW
                     NASSIGEFMVYFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQRVIFIALFHAG
                     WFVESLWTQTLVLHALRTPKVPFIQSNATFAMFVITTLGIIVGSVLPFTSFGAELGLM
                     PLPGNYWLWLFATVIAYLALVTAVKKIYIRRFQELL"
     gene            62895..63332
                     /gene="ndk"
                     /locus_tag="RD451_000282"
     CDS             62895..63332
                     /gene="ndk"
                     /locus_tag="RD451_000282"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HDT7565580.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAADAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(63354..64220)
                     /locus_tag="RD451_000283"
     CDS             complement(63354..64220)
                     /locus_tag="RD451_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDT7565581.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICFKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLNLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLSHKERSTVIYETLMADYYQRLISAALGEEKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
     gene            complement(64380..66473)
                     /locus_tag="RD451_000284"
     CDS             complement(64380..66473)
                     /locus_tag="RD451_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HDT7565582.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVGKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKNNQ"
     gene            complement(67222..67845)
                     /locus_tag="RD451_000285"
     CDS             complement(67222..67845)
                     /locus_tag="RD451_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565583.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHDGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
     gene            complement(68004..69401)
                     /locus_tag="RD451_000286"
     CDS             complement(68004..69401)
                     /locus_tag="RD451_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDT7565584.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHAEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            complement(69433..70404)
                     /locus_tag="RD451_000287"
     CDS             complement(69433..70404)
                     /locus_tag="RD451_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDT7565585.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            70778..71203
                     /locus_tag="RD451_000288"
     CDS             70778..71203
                     /locus_tag="RD451_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565586.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DTTNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGTDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKETTVIFTKIGNYRLKDEDGNIYSL"
     gene            complement(71691..72392)
                     /locus_tag="RD451_000289"
     CDS             complement(71691..72392)
                     /locus_tag="RD451_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HDT7565587.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
     gene            complement(72408..72848)
                     /locus_tag="RD451_000290"
     CDS             complement(72408..72848)
                     /locus_tag="RD451_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HDT7565588.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            complement(72848..73423)
                     /locus_tag="RD451_000291"
     CDS             complement(72848..73423)
                     /locus_tag="RD451_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HDT7565589.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            complement(74271..74750)
                     /locus_tag="RD451_000292"
                     /pseudo
     CDS             complement(74271..74750)
                     /locus_tag="RD451_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339057.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            complement(74909..75610)
                     /locus_tag="RD451_000293"
     CDS             complement(74909..75610)
                     /locus_tag="RD451_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDT7565590.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            complement(75718..77127)
                     /locus_tag="RD451_000294"
     CDS             complement(75718..77127)
                     /locus_tag="RD451_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HDT7565591.1"
                     /translation="MEQLLPNQLEGAYDRDGKGLSVADAMPGGKQRFAIIGSEEFDWT
                     IDQEKYIYPNHRGIDHYDRFKEDLALFAEMGFKCYRFSIAWTRIFPNGDEGTPNEAGL
                     EFYDQLIDECLKYDIEPVITISHYEMPLHLAKEYGGWKNRKLIDFYERFAQTVLERYS
                     SKVKYWMTFNEINSAFHFPALSQGLVKSNGAGEYQNIFQAWHNQFVASSKAVKIGHEL
                     RSDIQIGCMIIYATTYSIDANPVNQAATMIQNQEFNFFCTDVQVRGEYPAYTARTHKK
                     YGVDPEKLEQTEKDFQLLKEYPVDYIGFSYYMSTAINETDPQAATSEGNLLGGVKNPF
                     LEASEWGWQIDPEGLRIALNELYNRYQKPLFIVENGLGAIDHMEEDGTIIDDYRIDYL
                     RRHIEAMANAVADGVDLMGYTPWGCIDLVSASTGEMSKRYGFIYVDLDDEGNGTLNRS
                     KKKSFDWYKEVIASNGVNL"
     gene            complement(77175..79040)
                     /locus_tag="RD451_000295"
     CDS             complement(77175..79040)
                     /locus_tag="RD451_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDT7565592.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            complement(79161..80011)
                     /locus_tag="RD451_000296"
                     /pseudo
     CDS             complement(79161..80011)
                     /locus_tag="RD451_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
     gene            complement(80321..81034)
                     /locus_tag="RD451_000297"
     CDS             complement(80321..81034)
                     /locus_tag="RD451_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HDT7565593.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYFVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PVFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEGKEIVTLITCGDMDAVTRLVVQGELESVTS
                     IKDATDDMRSAFNLETKTF"
     gene            complement(81102..81428)
                     /locus_tag="RD451_000298"
     CDS             complement(81102..81428)
                     /locus_tag="RD451_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HDT7565594.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLHLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEL"
     gene            complement(81551..81778)
                     /locus_tag="RD451_000299"
     CDS             complement(81551..81778)
                     /locus_tag="RD451_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003246265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDT7565595.1"
                     /translation="MLTQQLRELEQDESIHRKAYNQVPPKVEYSLTEEGKSLREILVA
                     LSVWEEERIEKQKASREEDTLLHTHGGYLNY"
     gene            complement(82100..83353)
                     /locus_tag="RD451_000300"
     CDS             complement(82100..83353)
                     /locus_tag="RD451_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HDT7565596.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGCIALMVVTLL
                     LPIPKVSFPYLVGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGSRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            83414..84154
                     /locus_tag="RD451_000301"
     CDS             83414..84154
                     /locus_tag="RD451_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7565597.1"
                     /translation="MKKYFIIEDNQFHSEWIIRELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            complement(84240..84998)
                     /locus_tag="RD451_000302"
     CDS             complement(84240..84998)
                     /locus_tag="RD451_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HDT7565598.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPDEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QSGTDSTGAQTQVQNFVQVTDKSGNYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGMPSTVSGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEEEA"
     gene            complement(84995..85246)
                     /locus_tag="RD451_000303"
     CDS             complement(84995..85246)
                     /locus_tag="RD451_000303"
                     /inference="COORDINATES: protein motif:HMM:NF023225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3324 domain-containing protein"
                     /protein_id="HDT7565599.1"
                     /translation="MRRKKLAPGHYQAVVKGAWKEKRWNLHTDFEITDDAADQLNEKD
                     IDLKNQPETFDWRWLILVGVILIGLFAGLFILKERRKKK"
     gene            complement(85228..85449)
                     /locus_tag="RD451_000304"
     CDS             complement(85228..85449)
                     /locus_tag="RD451_000304"
                     /inference="COORDINATES: protein motif:HMM:NF023225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3324 domain-containing protein"
                     /protein_id="HDT7565600.1"
                     /translation="MKLKKAYADQSDGRNVIKANLQNPNASYMFGLTTSVEIYKKETK
                     EPYLSIKKEKIDVAPNTNFDLLVPLEGKN"
     gene            complement(85477..86022)
                     /locus_tag="RD451_000305"
     CDS             complement(85477..86022)
                     /locus_tag="RD451_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 domain-containing protein"
                     /protein_id="HDT7565601.1"
                     /translation="MNRIWNKSHRNNCSLLMILLLGFILWQTPVHASEFNFAVDFELP
                     ANQIDKNKTYINVRMEPGKTQEIPYTVFNRTDKSVTVETLIHSATTNSNGVIEYGESK
                     SKFDETLSYDMKNLAKTVGEITVPPQSAVTETLSLKAPEKELAGVVAGGITFQEKKEN
                     VSNKSTVGVVNQFSQVKAILI"
     gene            complement(86042..89209)
                     /locus_tag="RD451_000306"
     CDS             complement(86042..89209)
                     /locus_tag="RD451_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565602.1"
                     /translation="MNQCVKKLIASILFVFPLLMVTSVFADVEKTNESTQSENQSFDK
                     TTFSEESITSETTESQSEASTNKRQEENKTSETSEVAEQTSDSSEAALARAVSADGYS
                     EAATTEELAQLLADESVTKIRLIQPLTLDRELEIKRDIVIDFGGFAHNFGTHHIYINE
                     IPQSIEFQNFKGTAAHPGGLTPNIDGNAIIIAYMTDFWGSRYHFTGEIKFTGTLDLYD
                     GSKLGLIYAPRATVTLDGVSGVLDVQPVKEGLNAAPGKAYFCRSYQLNVINGSQLYGP
                     YLGKFYGFLDSGDETGSGKTAPGIHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVMF
                     EVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSKVTVSNGGKITINTATTGGFRLQGD
                     SSQIHVSSGGQISVKMAGDDDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSAV
                     RFENGTQKLTVTNGGSLRVRNTGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFTV
                     TGEKSNIDIRADSGATVDTTGDIDLNFTAGEKTYLVMVGKTGEDKTGIISGDVLNVDL
                     ESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKTGATFDNFEKDPD
                     YFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRVP
                     TNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSSVEITALTQGQTDEN
                     EGAGYNPWGEGEQGGLFEVQVPNDERLKTEDQVQVVAAKKVRGGQEVTELDSAKTTVD
                     VIPPEPANLSTTLINAASRTITGTGEAGALVSLKKNQAVLSETTIDDTGEFVLSIPEN
                     QLFAGDVLEIVLNDQAGEATAKGVQNKPSTNDEIGNHNPSDTPVVYHDAPPFAPATKI
                     VVEGGLSFLAPSKLDFGQIKATGLTQEAFGQMDIQEKLWIYDQRETKNPWILTIKLSQ
                     PFTNDAGFSMQDVLYFKKGEEYQLVNEEELEIVRGQNSTNVQADYSEYLNNGRAFKLV
                     LTKENQIAGNYSAEITWTLADAPTE"
     gene            complement(89433..90317)
                     /locus_tag="RD451_000307"
     CDS             complement(89433..90317)
                     /locus_tag="RD451_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HDT7565603.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPESINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSTLLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            complement(90412..90849)
                     /locus_tag="RD451_000308"
     CDS             complement(90412..90849)
                     /locus_tag="RD451_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565604.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWMFYLVKK"
     gene            complement(91066..91977)
                     /locus_tag="RD451_000309"
     CDS             complement(91066..91977)
                     /locus_tag="RD451_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HDT7565605.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
     gene            complement(92434..92862)
                     /locus_tag="RD451_000310"
     CDS             complement(92434..92862)
                     /locus_tag="RD451_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565606.1"
                     /translation="MKKAVIICALGIGFVGGNAMSSEVEANSVHGEIYYKSLKPGEIH
                     FDAKGNIIKSNLPVDREISRTAINHSSGRWVYYSDTTCTRKTGHSNHYSRVYNRHGAK
                     AKVGNSIRSANATKGVWAYASATGNRTDTFSCWYNPTGWY"
     gene            complement(92890..93528)
                     /locus_tag="RD451_000311"
     CDS             complement(92890..93528)
                     /locus_tag="RD451_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7565607.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDLVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFDQETKQLTGREKRLIKRNTISFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKDKVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            complement(93532..95514)
                     /locus_tag="RD451_000312"
     CDS             complement(93532..95514)
                     /locus_tag="RD451_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HDT7565608.1"
                     /translation="MSGFALVSINKQVLYRTNEFFHQTDTYTPIRLPQHFIGQEEYEQ
                     LIMVFENVSSETELSYMKKTVNESNEVDTSWNFKIQPKLEMTLYYQGDVKSSHEKVPY
                     SNTSFRVTSIEESIKIKDFEGEFFLMTREKEAYERFISLFTDRFNQAFHTDYATNIFE
                     DFENSYSYSVISNTDVYNYRVYLTIGLILLFLLLSSFFLLMNKEISLLLNNDFSLHQV
                     LWCLLGKKKIIITFIIAGIIGGFIFMYYKEQFLYLFQMYVFLFSGIYGISLISLLLVE
                     KIASLREAFNYIQYILFTFGLLFSLLLTVANVELATIVFSSSQLAVSHEPPKEIAGED
                     YHVFYPVTIGKNHVDFIYSNRFASAADQELYETLNKNGSILVNVSDYLNEENEQFGRG
                     IKINLNYLKKFPLIDVSGRLIQITEKETHPVILIPERYRHTDLKNDLAQITEYYQEIS
                     EKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSMYLERNILSGEIYPPLKIK
                     IGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLSRSFHYLIQIFLLTFFSFF
                     LLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNLIKWGTTSVIFLFLIEREP
                     KYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            95694..96359
                     /locus_tag="RD451_000313"
     CDS             95694..96359
                     /locus_tag="RD451_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7565609.1"
                     /translation="MNTGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDL
                     EMLSLLHHTLGLPIDFPSIESATESIEPTLPDEPLVNKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETIDRFNPFLKPQIGYTTLPVGYVDNSIERWVCNDIFGHGTW
                     LSFHAGEVEKEKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILSQDYDDALKRSPQEP
                     DRH"
BASE COUNT        28482 a        20107 c        16767 g        32275 t
ORIGIN      
        1 aaataaataa tataaaaggt aaataaaaaa gagtggattt ctccactcca tgaaaagccg
       61 actttttggg acgctttttt ttgccaagcc tcacattttt atagccaaac ttcttttgcg
      121 acttgctgca ataattggat tttcttccat tgttcttctt ctgttaaatg gtttccttct
      181 tctgttgaag caaacccaca ttgaggactg atacttagat tttccaatgg tacaaattgt
      241 tgtgcttctt ttattcgttc ttttattttc tccgtatctt ccaaatctgg aaacttagaa
      301 gtaactaatc ctaaaacaac tttactttct ttgttactcc aatgtcttaa aggagtaaaa
      361 tctcctgctc ggtcagaatc gtattccaaa aagaaaccat cataatttgt tgaaaacaac
      421 tcttctgcaa tgggttcata tccaccggaa aacagccaag aagaagcgtg attcccgcgg
      481 cagatatgtg ttgtgatcgt caaatcttct ggtttgtctt ccagtgcgtt attgataatc
      541 tctgtacaaa tatgggccat ttctttcgga tcaattcctt tttgaagaag tgcttctctt
      601 ttagtttgat cagctagaaa cgcccaattt gtatcatcga attgcaggta acggcaacct
      661 ttttcataaa aagcatgaat cgctgctttg taagtagagg acaagtcctc ataaaaatca
      721 gatagatcag gataaatctc cttgattttt gaagaaccat cattagatag gatctcttgt
      781 cgtaaaatca tcgtgggact agggatcgtt gcttttgcaa caaaagtatc atctgtttcc
      841 actacttctt tcagaaaagc aaaatctttt aaaaatgggt gatttggatt gaaagataat
      901 ttatctacta cccgaatatt ataagctggt gctgcttttc cgtggaatgt ttgattatat
      961 ccagtttctg gaacatagcc ttcgatacca tttagttctt ctaaaaaatc aagatgccaa
     1021 aatccacgcc gaaattcacc atctgtaatt cctttgatgc cgactgcttt ttggtcttcc
     1081 actaattttt ttatttcctg gtcttcgatt gcacgaagtt cttcttttga aagtaagcct
     1141 tcttgaactt tttttcttgc ttctttgatc gattgcgggc gtaagaaact tccgacatga
     1201 tctactgtaa atggtctatt tttgctcatt tcactcactc ttttctttgt tttttgtaaa
     1261 aaaaaatcct tttactagca aatactagta aaaggacgat tatactcgtg gtaccacctt
     1321 ttttcagaaa aaacattctt tctctcagcc tgacaataaa atcagtggtc ttggtaacga
     1381 aagactgttc gtttttgcct acctttcgac aaaaaatcct ctaaggccat tttcgacagt
     1441 caacttctag ctttttacac caaccaaagc ctctcttgaa ccattttctg tctactttcc
     1501 ttctcatcgg atactattag aataaaatta gaatagcatg tttgaaagaa aagtcaatag
     1561 ggaataagaa caaacaaaaa ctaatttgtt attcttagta atttgtttgt ggaatacaat
     1621 aaagcttttc taatatgata attgttcagt cgtcctttca tcttagatca cttccttaaa
     1681 atgatcatac ccgtttcaac cacataaaaa aggacttaat tttgaaaaat ttcccatcaa
     1741 aactaagtcc tttttattat agttatgcaa atttgcttat tttctcgcta tttccgatac
     1801 atcttgaatt ctaagaatag gtcattatag atgcctaggt atttcgatcc tagatctttg
     1861 tagacttcaa gatgggagat cgtgtcatca gatggataga attgttcgtc cgacgaaatg
     1921 tcttttggca ataacgcttt tgcttcttca tttggtgtag aataaccaat atactctgca
     1981 ttttgtgccg cattttccgg ttctagcata aagttgatga aatcataggc accttcttta
     2041 tttttcacgg tttttggcat aacgatatta tcaaaccaaa gattggatcc ttctggtggg
     2101 atcacataat gtaaatgttc attttcccac atcatatcgg cagcttcgcc agaaaatgtc
     2161 actgccacgg aggcttcttc attgatcata tacattttga tctcatctgc cacgattgct
     2221 ttgacatttg gtgttaaatg attcaattta tttgctgctt ctgtcagctg tgccatattc
     2281 ttactattca aagaatagcc taaactattc aaagaaagcc ccataacttc tcgtgcaccg
     2341 tcaatcagca tcaaactgtc ttttaattcc ggcttccaca aatcatccca atgcttaatt
     2401 tgatttgcat caaagaattt atcgttatat acgatcccta aagttcccca aaaatatgga
     2461 atcgaatact gattatctgg atcaaaatcc aagtctaaaa atcgtggatc aatattattt
     2521 aatcctttga tcttcgaatg atctaatgga agtactagtt tttctttgat cattttttgg
     2581 atcatatatt cacttggtat agcgatgtcg tagtttgtcc caccttgctg gatttttgtg
     2641 aacatcgctt cattagaatc aaatgtttca taattcactt tgtatccata ttctttttca
     2701 aatttcgtga tcaaactagg atcgatataa tctccccagt tatagatggt aagtaccttt
     2761 gctccactca tgccacttgt tttttcaagt tgacgaacac caagcagcag caccgcaata
     2821 atgatgagaa tacctaaaaa cagagattgt aattttttca tcgcagccgt gccaccccct
     2881 cgcgtactct tctgtttttc ttcagccgtt ttggacggtt ttctttacta ataaagtagt
     2941 atccaatgac caatatcatg gagaacaaga aaactaacgc acttagcgca ttgatttcta
     3001 aactgattcc ttgtcttgca cgagaataga tctctactga gagcgtcgta aagccatttc
     3061 ctgtgacgaa aaatgtaacc gcaaaatcat caagagaata ggtaaatgcc ataaaatatc
     3121 cagctatgat tcctggagaa agataaggca aaatgatatt tttgactact tggaaattat
     3181 tagcaccaag gtctctagcc gcatcgacca ttgaatcgtt catttcctgc aattttggca
     3241 agaccatcaa gacgacgatt ggaatgctga aagcaatatg ggaaagcaat acactctgaa
     3301 aacctaatcc gaatcctagt agtgtaaaga aaatcaagaa actagcaccg ataataacat
     3361 caggagagac taataagatg ttattcatgc tcaacaacgc tgtccgtgca cgtcgttttt
     3421 tcgtgtaata gattcccata gccccaaatg tcccgatgat cgtggcgatc aatgcagata
     3481 agaaagccag catgaacgta ttcaatacga taatgatcaa acgtgtatct tcaaaaacag
     3541 cttcataatt ttcccaagta aatcctgtaa agctgttcat cgttcctcct tcattgaagg
     3601 aataaaaaat cagatagaag atcggtgcat ataagaataa aaagacgatc cctaaataaa
     3661 gatacgacca tttaaatttt ttcatttatg agcgacctcc ttttttcttc tcgcctgtca
     3721 ggagcatcac gatgaacata gcaatgatta aaatcacacc gattgtagaa cccatccccc
     3781 agttttgtgt aaccaagaaa tgctgttcga tagccgttcc taaagtgatc acccgatttc
     3841 cgccaatcag acgagtcagc atgaataaag aaagagaagg aataaatact gcttggacac
     3901 cacttttcac accatttaat gataacggaa aaatcactcg tcggaaggtc tcaaagctat
     3961 tcgcgcctaa atctctacta gcactgatca aagaaggatt catctcttcc aatgcattga
     4021 aaattggcat aatcataaat ggaatctcga tatacgttgc cacgaacaga aaactgaagt
     4081 ctgtgaataa tatctgtttc ggcccgatcc cgataaaatc aaagaaatga ttcacgctgc
     4141 cgtgcacact gaaaatccca ataaatgcgt aagctttaag cagcagattc acccatgtag
     4201 gcaaaataat cagcatcagc cataattgct tgtgcttcag ttttgttaaa aaataagcag
     4261 tcgggtaact gatgatcagc gtgaaaaacg tgatcaaaaa tgcataccat acagaattga
     4321 tcgtcataga aagcgatgtc cccgacgtaa aataagatag ataattattc agcgtgaatt
     4381 gcccattcat atcaaaaaaa gattgataaa tgatcattaa tacaggcgcg atcacgaata
     4441 aaccgagcca caaaatataa gggacggaat agatcctgcg cattgttttc attcttgtcc
     4501 cccctattct tcgtagctgt caagacgtgc atcgaattct tcttcagact cgttgaaacg
     4561 catgacatgg atatcttctg gctcaaaggc caatcctact ttgcttcctt ctttagcttt
     4621 tttcgttgaa tggaccatcc attcattttg ctgttcatca taacagatga tttcataatg
     4681 gacaccacga aacagctgag tatcgaccgt tacgactagt tttcctttat ctggtgtcgt
     4741 gatcgtcaaa tcctctgggc gtaaaacaac ttcaactggt tcatttagac gcatcccgcc
     4801 atcgacacat tcaaattgct taccaacaaa ctcaactaga ttatcttcga tcattacacc
     4861 gtccacgata ttgctctccc caacaaaatc agcaacgaaa tgattgattg gctcatcata
     4921 aatatctacg ggtgtaccac tttggacgat tttcccttta ttcatgacaa aaatctcatc
     4981 actcattgcc aacgcttctt cttggtcatg agtaacaaaa ataaacgtga ttcctaatcg
     5041 ttgttgcaga tcccgcagtt catactgcat atctgtacgt agtttcaaat caagcgccga
     5101 taacggttca tctaatagca atactttcgg ttcatttaca attgctcgtg caatcgctac
     5161 acgctgtctt tgaccaccag acatttcact aatctcccgt ttttcgtatc caggaagctg
     5221 gaccatacgc aaagcatctt ttaccttctt ttcgatatct gatttggaca ttttcttgat
     5281 cttcaatcca aaagcaacgt tatcaaaaac attcatatga ggaaaaagtg cataatcttg
     5341 gaagactgta tttacttgtc gcttattagc tggcaaatca ttcaaccgtt tcccttcaaa
     5401 atagatgtcc ccttctgtag cttcggtgaa tccagctata atacgtagga tcgttgtttt
     5461 accacagccg gaaggaccaa gcagtgtata aaattttcct tgttcgatct caaaacttac
     5521 tttttttaat actgtttcat catcatagcg tttcactact tgatcaaatg aaatgattgg
     5581 tttccccacg tttttacccc ctatattaca aatatgattg cgttgcaaca atcaatactt
     5641 ttgttcgttt tttgagatga ttccttaatt gatgttgttt tgtcgcttga taatagatcg
     5701 actgtcctgc ttttgccaca tagaccgtct ctcctaagct taactctaat tccccttcta
     5761 atacaaaaat aaacgtttca gataatgaag gttcaaacgt cttatattct cctgcacctt
     5821 caaaagtcag caagacaggc tccatttctt tttcattcga atcagccacg agccattcca
     5881 attcataccc gttttcttca tcgaaataaa ccgtatgatc ttcttttgaa taaaccactt
     5941 gcagattcgc tgcttcttga tgaaaaaatt cttctggagt cacacctaag acttcaagaa
     6001 tagaaaagaa tgtttccatt gatggtgaac ttaaatctcg ttccaactgg gaaatatacc
     6061 cttttgacaa atctgtgcgt tcgcctagtt cttcttgtgt caaattcttt tggatgcgca
     6121 aatttcttaa cttctcacca atttccataa tttcctccga atcgaagttt tctaatagta
     6181 aacttcctgt ttactaccac tcgtattagt atacgaaatt tattgaaaaa ggcaaccctt
     6241 tgtaaaattt tttttgctga atatttcttt atcttttgga ataaattcta gttgtttgat
     6301 tctttatttt tcacctaatt tttgtctaaa tttacggaag aacaagaata aaagagtagg
     6361 ctttatggta tgataaaaga aaattttaaa aggagtgtct cacgaatgaa cgcttttcga
     6421 tcttttcagg taataaagga acctgttttc catacagcaa tcagtgatct gccatttact
     6481 gagttggctg aaaatgaagt cttggtaaaa attgcctatt ctgatgtcaa ttataaagat
     6541 gcattggcaa tgagcgagtc tggtcaggtg atacgaacat atccgatgac tccagggatt
     6601 gatttatccg gaactgtcgt ccaaagtaac aatccacgtt tttcaaaaga agatcttgta
     6661 cttgctactg gttttgggct tggcgtcacc catccaggcg gttatagcca atatcaaaaa
     6721 gtaccaggag actggttagt tcctctacca aaaaatatga cgctgcgtca agcgatgatc
     6781 cttggtacag cagggtttac tgctatgttg tgtgtgaacg ctttaatccg tcaaggtatg
     6841 acctccgata aaaaagttgt cgttactggt gcttctggcg gtgtaggcag tacagcgata
     6901 gccctgttac ataaactagg attccagtca atcattgcct tttccagaaa agaagagtct
     6961 gtcacatggc taaaaagtct aggtgctttg caagtcgtac gacctgatga atttctgcca
     7021 gagacaacaa aagctttagg aaaacagcaa atcgactatg tcatcgacac agtaggtggc
     7081 gagcagctaa gcagtcttct tccattgatc tcttataacg gtgcagtagc tttatgtggc
     7141 aatgctgggg gaatcaaact aaacgcgact gtcttgcctt ttattctgcg aaacatccag
     7201 ttgattggaa ttgattctgt caatgtacca atagatcaac gtctttcttt atggcaacag
     7261 atggcggatt tgcagattgc agatgaactg gtcgtccaag agattactct ggatcaattg
     7321 cctgaaacag catctaaact acttgctgga acacaccaag gaagaacact agtaaatgta
     7381 ggtgaccata aatgaagatt ctaatcacag ctggaggaac gactgaaaaa atcgatcaag
     7441 tacgtgctat tacaaatcat tcgacaggac gattagggca agcattagct gattatttag
     7501 ctgccaatcc ggataccaca atcgattacg tgactacgaa acaagcactg aaaccgaaaa
     7561 gacactccaa tataacgatt tatacgatcg aatctgcact ggacttattt ttacaattag
     7621 aagaactaac gaaaaaagaa cactacgatg cgattatcca cagtatggca gtcagtgatt
     7681 ttactcctgc ttttagtttt tcagaagaac agctggcaaa aaacctaccc acttcttcaa
     7741 cgcaagaaga actggacaat tggtttgcgg aaaatgaaca gacagatacc actgtttcaa
     7801 agatctcttc taacaccgag catcttgtgc tcgttttgaa gaaaacacca aaaatcattt
     7861 cttatctacg tgaatggcag ccaaaagcaa aaatcattgg tttcaaacta ttagtagatg
     7921 taccaaagga atctcttctg gcagtcgcaa aaaatagtct gataaataac aaaactgatt
     7981 ttattttcgc aaatgatttg acggaaatcc atggcgagac acaccacggc tatctcttat
     8041 ctaaagatgg aacagtggaa gaagctcaaa gtaaatctga gattgctgca ttgattactg
     8101 agaaaattag actggaggaa tcaaaatgaa aaagatctta ctaggcgtta ctggaagtat
     8161 ttctgcttac aaaagcgctg atcttacaag tcaattcgtc aaattaggtg cccaggtaga
     8221 tgtgattatg tctaaaagca gcacacattt tatcacgcca ttaaccttgc aatctctgtc
     8281 gaagcgcgca gtccatacag acgtcatgca agaatcaaat ccgcaggtaa tcaatcatat
     8341 cgaactagca aaacaagctg acttgtttct catcgcgcct gctacagcaa acattatcgg
     8401 caagctagca aacggcattg cagacgatct tctttcaaca gtcgcaatgg cgcttccagt
     8461 gggaacacca aaattgattg cccctgccat gaacacgaat atgtatcaaa acccgatcac
     8521 tcagcgtaat ctggaaacat tgagatctgt cggctatcag gaaattgaac caagagaatc
     8581 tcttttagct tgtggagatt ttggaaaagg tgccttagct gatattcaga cgatcatcga
     8641 acaggtcatg ctgactctta atgaaagaaa tgcttagaaa aaaggagtac ttatgaaaaa
     8701 tacaaaaaac tttacattaa ctgcgatgtt tttagctatt ttgattttat tagctgttac
     8761 gcctttaggt tttatcccta tcggtccaat caatgcaaca accatgcata ttcctgtaat
     8821 cattgcttcg atcgttttag gaccaagact aggtgctttt cttggcggta catttggact
     8881 gatcagcatg atccgtagca cagttatcca aacacctttg tcttttgtct tttctccgtt
     8941 tatcccagtc atcggaacag aacatggaag ctggaaagcc ttgctgatcg cgtttattcc
     9001 tcgcatcttg attggggtgg ttccttattt cgtttataaa ggtctgcgca aactaatgaa
     9061 acaaaaagca gattccgttt ctttattctt agctggactt tccggttcat tgaccaatac
     9121 gattttagtg atgaatatga tctacttttt attccagcaa gattatgcca aagtcatcgg
     9181 aacaaattta aatgctgttt attcagctat tctagcggtt atttttacaa gtggtatacc
     9241 tgaaggaatc gtcgcaggtc ttgcgactgc agcagtatgc aatgtcttgt taagatactt
     9301 caagcaccct tctcttacta actgatagtc atcgtagccg atctctgatt tttttctctt
     9361 ttggtgttac tattgaatgg aaagatttga cgtcgaaagg atgatccaaa tgaaaatttt
     9421 tgttgtaggt gcaaacggac aaattggccg acacctgata aaagatttag ctccaagttc
     9481 ccatgaaatt tttgcagggg tgagagatgt tgcttcccaa acattagtaa aaaaagagaa
     9541 tgtttcgtat gtctcttttg atttaacttg gtccgtggaa aaaatgaccg aagcattcaa
     9601 aggcatcgat gtattgattt ttgctgccgg ctctcaagga aagaatcttc tgcaagtaga
     9661 cttggatggc gcaatcaaaa cagtgatcgc agctgaaaat gcgcatgtct ctcgctatct
     9721 gatggtcagt gctgtttatg cagatgaacc agcaaaatgg cctgagtcca tgacagatta
     9781 ttatattact aaacattatg cagatgaatg gctgaaacga actaacttag attttgtcat
     9841 tcttcaacca gtcacattga ctaacgatga agaagttact tccattcaat taactaagcc
     9901 taatgagaag gcatcaaaaa cgatcactcg ctctacagtt gctgctgtac ttgccgctct
     9961 agtggaagaa acggatattt ctcgtacgac tctagtactt tctgaaggta gcaaagagtt
    10021 gaatacagca ttccaagaat gggcaaagga ggaatagatc catgcgtgcc atttcaatca
    10081 agcatcctgg ttctgtagat gtattagaac aaattgaagt gcctgttcct aaaccaaaac
    10141 aaggcgaatt actgatcaaa gtccatacag cagctgtcaa tcgaacagat attatgaaaa
    10201 gagaatcagt ctctttgaaa cctccctacc ctattttggg agtcgaagta gctggagagg
    10261 tagttgagaa taaaagtgat atctccactt ttactcctgg gacaaaagta tacggattag
    10321 tcaatctagg tggttatgcc gaatatgctg tgatgcctgc cgatcgtgca atccttctcc
    10381 ctgatacgct agactatgtt tctgctgctg gaatctcaga agtttttttg actgcttatc
    10441 aaacacttta ctggcttgga aaattacaag aaggcgaaac tgtcttgatc catgcaggag
    10501 caagtggtgt gggaacagca gcgatccaat tagctagaca gctttctcac gcgaaaatca
    10561 tcgttactgc aggatcagaa gaaaaactcg ccttttgtaa agaacttggt gcagatgaat
    10621 tgatcaacta taaaaaacaa gactttcaag aagaggtacg aaaaatcact gaaggtcggg
    10681 gagtcgatgt tattttggat ttcatcggcg cttcttactg ggaaaagaat ttagcttcta
    10741 tagccgttga tggacgttgg gtcttgattg gtatgctagg tgggaccatc gtgcctgaga
    10801 tagaccttgg tgtattgatt gggaaacgtg tccaactgct tggtacatta ttgacaccta
    10861 gaagtgatca gtataaagca gagctcgcac aaacttttat gcaaaaagct gggccttttc
    10921 tagaaaatgg caagattcgg ccaatcattg accgtacatt ccaattcagc gcagtcaaac
    10981 aagcgcatga atatatggaa gcaaacaaaa acatcggaaa aatcattttg aagataactg
    11041 aataaaatca tgctgatcaa aaaagaggct gggacagaag cgtttaactc caagaaataa
    11101 gaagaaattc acgaaaattg cttttcaaat ttttgtgaat ttcagcttat ttccgaagga
    11161 atttcttctg cttccgccgt ttatacgtgt ttagagcgtg agacaaaagt gttctttact
    11221 tttgtcccac gctctttttc cgaataaacg gtgttcaaaa gcttgcatct gcggtaataa
    11281 gtccaaccaa gttaaaaaca taagaagctg tttttacttg gctgttctta ttacttgatg
    11341 cagggcagct ttttcacaac ctcttcacta aacagtgttc aatcagctga ccctcggtat
    11401 tagctcaaaa cgctgatttc acaacctctt tttatttacg ttctatttca ttcattttcc
    11461 gaagcaaatc gagctgcttg tatgcccgct tgtcgcccaa aaataatgat ctccgcaact
    11521 gaatttccac cgatccggtt gtttccatgt aagccacctg tgacttcacc agcagcatat
    11581 aaccccctaa ttggctggtt ttctttatct aatacttcag tgttcgtatt gattttcaca
    11641 ccgcccatcg tgtaatggat tcctggtgcg attttgatcg cataataatt cggagacgat
    11701 aagtcatgtt ccatggctgt ggcacggttg aattgagcat cttttttctc cgcaacatcc
    11761 gtattccatc catcaactgt ttttgctagt gtttcttttg gtaaatcgat tttttctgct
    11821 aattcttcca ttgtctttcc agttgtgaca tatccttttt ggtcataaaa ttcaatagct
    11881 gtggcacgat cacgcacgcc ttggtcaaaa atcaaataag ctgatttttc aggcaatgct
    11941 gtaattgctg cagatacttt atcccttgta tccatttcat tgacaaatct tttcccctct
    12001 tgatcgacca agattgctcc ttctccgcga acaacctcac caatcaagac cccctcatcc
    12061 tgctgcacag ttggatgaat ttgtatttta tccatatcaa cggtttgtcc acctaatttt
    12121 tcaatcatgg tgataccatc tccagttgat ccttcttgat ttgtcgtaat ataatcagct
    12181 aaatcgggac gatatttttc aataaattct ttgctggcac caaaaccgcc tgtggtaact
    12241 acgattgctt ttccggtgac ctcttttggt tcttctcctt gaacatgtac agtcacttca
    12301 ttgaccgttt ccccattttt cttaatgtct gtcacatctg cgttgacaaa aatagggatt
    12361 tcccgctcat ggacgttatt caataacccc tccactaagt atccaccaat agccgagcca
    12421 tcagacggac gatgtgtcct cttttcactc atccctccag tgatcgttaa gttgtccagt
    12481 ttgataccgt tttgatctag ccaatcgacc gcatcagcag agtgatcgac aaagtatcga
    12541 agcatttctt tatcattcgt tcctccacca ccttttagcg tttcttcata gaaggcatca
    12601 ttcgagtctt tgattccttc ttctttttga aattttgttt ctgaagcatt cataccgctt
    12661 gatgatttag atgtgtttcc tccggcaaca ggcatctttt ccaaaattac tggattcaac
    12721 ccagcatctt ttgcttcgat agctgctgcc atccctgcac caccagctcc aataatcacg
    12781 acatcataag attctttcat ttcttttgga tctgtatata cttgttcaga agcgcctgat
    12841 gatacttcgg cagattcctt cgtactagaa cttgtctgcg ctgtattttt ctgatctgcg
    12901 ccgcatgcgc tcatagcaag aagtgcaacg gctgttaata aaccagcaac taattttttc
    12961 atttgtatcc cccttttctc cttatactat attaagtgat ttttttcaca atatcaactc
    13021 tgtttttctt taagtcatat agctttggta aacacacgct tcttagtata attaaggata
    13081 tacatgaagg agttatttta tgaatcattt gaaaaccttt tttacgaaca gtacaaaaac
    13141 tgcaggtaga atcacaaacg gaatctatat tttattacgt atcatcgtcg ttattatgct
    13201 agtggatcag gtctggaacc aacactgggg aaatacaatg cttttattac tgacattaat
    13261 tttatttgaa atcccttatt ttctggaaaa gatattaaag atacagattc caaatatgct
    13321 agaaatcatt ttgttatctt ttatttttag ttcaacagtt ttaggagagt taagtgattt
    13381 ttatggctat ttttcaatgt gggatacttt tctacatgca ttcagcggat ttttagctgg
    13441 gggtgtcggc ttttcccttg tttatttgct caataaaaat acaaaaacca tgaacttgac
    13501 tcctttatta ctagcagttg tttccttctg tttttcgatg acagttggtg ttatgtggga
    13561 gtttgtggaa ttttcagcag ataaattact gcaattcgat atgcaaaaag atacgatcat
    13621 ccagcaaatc aatagtgtgg agttaagtaa agacggaaac actgtctatc atgttccaga
    13681 tatcactcgg acaatcattg aaagtcaaaa tgcagatggt aaaacagata aaacaatcat
    13741 ccaaaatggt tacttagacg tgggaatcat ggatactatg aaggatttat ttgttaattt
    13801 tattggagca gttgttttca gtgtatttgg ttacctctat agtcgaaacg attaccaaaa
    13861 atttacgttc atcaagaatt ttattcctaa aaaaatcaaa cgataaaaca tgctaaaaaa
    13921 caagagaagg ggcagtgaca atacttttgt cactgcccct tcttttttga atgtatggca
    13981 tgccattagt tatccgatag tattaactca aaaaagtaag atatgaggaa tgactatttc
    14041 gttttttatc ccaatactga ggacttattt caccatttcg ttatttatct aatttactta
    14101 aaacctgcat aactttttca taatctggat taggtgtgcc gtctagattt tcagcaataa
    14161 aagtaaaacc cattttttta taaagagcaa tcgcctgatg gctccatgtc tgtgtgtgaa
    14221 gatagattgg tccgtccgta tggagggtag gaaattcttg caagactctg gcagtcaatg
    14281 cttttgcgag cccttttcct tggtaatctg gtttcactgc taaccaatga aaaaccggat
    14341 acacttgctc tcttgatttt tttcgccaag cggtacaggt tgctactttt tctccttttt
    14401 ttgtctctac aaaaaacatc cttctttcaa gttcttcagg ataaggagca aagttttgtt
    14461 gaaaatactc aagtgcttca tctgtcgttt gaaattcccc aacggaagtc tcaatctccg
    14521 cccaagcaga ttcatcttct ttttgataaa atcgaaattc aaaaccttcc gctaaaggcg
    14581 tgattggaac attttgttga agtggtcttg tcatccagat ttctgcgtaa ggtaacgttt
    14641 tatctaacat ttttctatcc ctcctcgtct ccattatgcc aaataacata tgactcagct
    14701 acttatttga ctataacaga tagagatata aatcagaacc agtcatctgc gtcaaattca
    14761 tttcgattag cgtataccca tgttcctgcc atacctcgca tgaaatctcc taaagcagaa
    14821 gaaggaatac ctccaccagg tgcgggtgtt cccggactag gaagtggtac ttgcggctgc
    14881 agatgctcat cggtggaatc aatagttgac aagcgttttt tcttcgtttc cttctggtca
    14941 tctgattcct tctgatcttc cgactgttta gcaacaaatt ctttttctga ttgttgtttt
    15001 attttaggct ctaaaatttc attttccaat ccagaaactt gtggggccaa atgagcttct
    15061 tgccttatcg ttttattaga ttctgagatt tttctagata ttcttgctaa ctctaggctt
    15121 cttgtttgtt ttactttccc tgttggagaa actgcatgag ccatttgttg ttttttttct
    15181 gacaagcttt cttcttgtct tttttgttct ttttgatcta tctgtttgtt taatggtaaa
    15241 acatgtaata gtgactgagc atggagttct tggagtgaat acgggtcatg ataactatac
    15301 ataatcgtaa aatcacctgt ttgtttggtc aaataaccat cctccaatgg tacttcattg
    15361 attgtaaccg atacatcctt taacggtacg ggtttaccta aggaatttgt tgctgattgg
    15421 atcaactctt ctttgtttat tttttcgttt ggatgaacaa taagatcatg accttctaat
    15481 gaacgattgt ctggtatata aacataagta aaggtaattt cccctcctga ttgcttccta
    15541 ttattcatca gttctgagtg aagtacttca aggatctccg accagtgact ttttctgtct
    15601 aatccgtttg cttgcatcca atcagaaata gaagtgactt tcccattttg ttcataagtc
    15661 gataaatcta tatttggcac tcgatcagaa aattcagcag gtaggcgcaa atcaggaata
    15721 cgatttacac tactcatatg tgtttctgct tgaagttctt tatttgtttg actatctata
    15781 aaatgagtga tgacagtcga tgaagcagca gatgcttcta cataaactac agctgttgtt
    15841 tctgccacat ttgatgtttt cgagtctata taagttaata caacgggata ttctcccgga
    15901 gttgtagtat ctactgtccc gttcattttg atttcttctt tatttcctga agttccatcg
    15961 ctttttgtta catattcaac aagatcttta ggggcgtaac tctctcctgt tcttaagtga
    16021 agatcttttc ctttgatagc tgtttgatca gcacgaacat ggatcacagc agatgcagtc
    16081 attgttttta aagcaattgg atcaaaatag gacaaggaaa tagtagatgt tcctgtatta
    16141 gtcgtatcca cgatattccc attgtttgaa attactttgg acatatctcc ttgtgttcca
    16201 tctgcgttct tcagcctttc taccagatca gatatcgaaa cttttgtccc tgccagaaca
    16261 tcgattttct ttctttcaaa ctgtgaataa tctttttcat atacataaga aacttgtgcg
    16321 cttccaccgt cctttatatc tgtcaaagca tgattcaaaa tatcagtgat ctgttttaac
    16381 tgatcacctt ttgtaggatc agtcatatcg gaaaagatag aaagcggcac actgcttccg
    16441 gtttccgatg tccataatgt tttgttagga attaaccagt agtggtttat cgttggagga
    16501 taactgactt tattatagga agtcaatgca ggaagtagct gttttccatt tgcatcagtg
    16561 aaagtatgag taatagtgat aggggaatca gtggtctcag aaacagaggt acgtacgacc
    16621 ttgatggttt gtgtcgttgc ctgaacgggt acatgcatat agacacctac agataaactg
    16681 atcagcatcg tgcgcatcat aaacttaacg tagtgttttt cagaacacga ccgttcctta
    16741 tctaaacgac aagcgtgttt atttagttgt tttgaacgtc tttttgaaca catttattct
    16801 tagtcctccc tactcttgtc taaacatgaa gtagtaattt tcataagatg atttcattat
    16861 ataaataaaa tcaaaagaag atggactatt aggagagtat tttttttgat tttttattgt
    16921 ttcaagaaaa tcggaataat aacttatgta ctttttaatt ttgttaagta atatatctag
    16981 ttatatctag ttatatctag ttaccttttc tttgaaaaaa acataaatca gctaataaat
    17041 atgtgagaca aagctgccat ccataaatac tagctgattt tttcagttaa atgtctattt
    17101 ttttctctga tgatggtatt tccaaaatat tcccagtcat ctggagtcgg tggatttttc
    17161 caaattatct gttctttatt aaatttttca agtaaacaat cagataaata aatattcgta
    17221 cgagaagtga ttcgactctc aatcacaata ttgtaatttt taaatccttt cacttgagaa
    17281 ataatgtaat cggtataagc agatccttgc gaaaaatcaa tacagacatg aatcggtgct
    17341 tcaaaatatg ataccggaca aataccgacc aataaaaaga gataatcata aaataagcga
    17401 atcatgaaac gttcatcttt tcccaagaaa tagcgtttat tctcttgtat gaccttttgg
    17461 attgctgtac tgaatattgg atacgtctcg aagaaaaact gtagctgctt tttagacgta
    17521 aagctagtca tctcaaagtc gaatatccaa ttttttcgat tgacatgcat catacccata
    17581 cgaagttctt ttcgtatata tagtctttct tcttcagaga tttcaatcga aaatggtaat
    17641 tgatcaatca attccactga cattttttga ctaatcatgt ggatatcatg aaaatgagct
    17701 tccgcaagtc caaatgcgcc atctaattca aattcttctt ccgtgatcaa aaacaacatg
    17761 atataagaaa tctcatcaat gatctgctct ttagggatat gaagaaaaga aatatgtgat
    17821 aaatccttga tgatcttcat tccttctgag ctcttaaagt attcatctga aaagaaacgt
    17881 tttccgattg gttgattccc ataggccctc aacaaactaa tagtggttag caaattgaat
    17941 ttgattcgtt ttgttgcaga cagttttaaa ttgaacagat attcaaaata ttgcacgata
    18001 ctctttgctt cattcatgac gctttctcta aatggcatag aaaaaccatt aaagaccccg
    18061 aaatataccc caaataatac gttccgtatg tttatttctt ccccaactaa tatgtttttc
    18121 tttaacttta tttgatgctg ttcaagaaaa gagactaatt ctcttctttt tacataggct
    18181 cttgatatgc ttaaaaaatg attctctgca aatttttcga tcgttacttt tgaatccacg
    18241 atctccgtta acagtcgagc aatttttgat cgttgaaagt agattcttct taaatttttg
    18301 atatccgtca aattcagacg ttcgacatgg atctctgctt cttctgaaat ttggatctct
    18361 ggctttgttt tgaattcagt aaattcttta tttaattcta tgatataatt tcttgtttta
    18421 aatttagaca aacctaatgt ttcatataac ttaggcagca ctacataatt ctttttctca
    18481 aattctaaat atctagctag cagcagtttt tctctatctt cctcttctat aaggtaatcc
    18541 aacttcatat cctacacctc aaaaaatgcc tcataccaat tacttgatat gcagatgaaa
    18601 gttcatcttt tcacctatac tgattttatg atggattatg cttgtttttt catcagttat
    18661 tctcattttt tatctttttt ttgagaatat tgcaaaaaat ggaaaaattt atgaggaaat
    18721 attctatatt ttttgtttta ttgtgttaaa atgtacaaga tttgcgccat ttgcgtaaac
    18781 aaccacaaaa aagagcagga cggccaccgt cctgctcttt tacttatttt aagttccatt
    18841 acttattaat tggctaaact tctgcttgtt tctgatattg cttgtttttc tccaatgatc
    18901 cgcacttctg tttctaaaga cacatcaaat ttttctttga ttacttcttg gatgtgcgca
    18961 atcaattcaa tataatctgt cgctgtcgca tgatcgatat tgacgatgaa tccagcatgt
    19021 ttttcagaga cttgtgcacc gccccatttc aggccttgca atcctgcttg ttggatcagc
    19081 tgacctgtat agtgtcctac tgggcgctta aagacacttc cgcatgaagg gtattctaat
    19141 ggctgttttg attgacgcaa ttcggtcaac tcatccattc ttgctttgat tgcttcataa
    19201 tcccctgttt gcaaactgaa tcgagcttcc aatacgatag cacgtaattc ttggacttta
    19261 ctgtgacgat aagaaaatac catttcgtct tttgtcaaag ttttcaatgt tccatcttca
    19321 agcaaaagat ccacttcagc aaaaacatct ttgatctctc cgccatacgc acctgcattc
    19381 atataaaccg ctccaccgac acttcccggg atgccgcaag caaattcaaa tccagtcaat
    19441 gattctgcca aagctgcata agtcgtatca atcagtgagg cacctgcttc cgcaatgacc
    19501 atcgttcctt tgacatgaat ctgtttcatt tcagtcagca tgatgactac accgcgaatc
    19561 ccgccatctt gaacgatcag attgcttgca tttcctaata ccatccaagg tatatcatgg
    19621 attcggcaat aatcgatgat ttgctttact tcttcttgtt ttttcgggaa tgcaaggaca
    19681 tcagctggtc cacctgtttt cgtaaacgta tagttcatca atggttcatc aaacaatata
    19741 gtaatcgtgg ctaagctttc aactatttct tctttattca ctgaggattt tcctttcttt
    19801 tctcaaacgt cctcattatt ctatcacgct taatacaatc ttgccagtct tgttcaaagt
    19861 tgatgacggt agtgatcttt aagcacttcc tcacataatt catgacttct tacaacttct
    19921 ttttgtttaa gcaattctgt ttccgattta cctaaacgga tctgagaaaa gaaggcctct
    19981 accattggct caaacccgcg tttgactagc gtgtttgtcc agtcgccaaa ttctttcact
    20041 ttttttccat cagcatcttg aatgacaagc tgggtcagat cgtttacttc ataagtacca
    20101 tttttacttg ttacttgata tttttctata ttagcgccac ttgctaaatc catcgttaaa
    20161 atagccgttt gattttgtgt ttctaattgt aaaatggcat attccaaaaa ttcctttgtt
    20221 tctcttatct ggtattttgt tctcaaaatg ggttcatcta ataaatacac agctgtatca
    20281 ataagatgta aaaacaaatc ataaaggacg aactctgtcg tttcttttgc cgctattcga
    20341 tttttttgca ggtggatcaa ccgcttatct gggatacgtt tcaattcttc taccatagga
    20401 gcaaagcgcc ggttgaaacc gatcatcaaa attatttggt tcttatcagc taattcttgc
    20461 aattcacgaa cttcatttag atggacactc agtggtttgt caatataaac atggatacca
    20521 ttttctagac attttttggc taattcataa tgtacttttg ttgctgcgtg gatcatacat
    20581 gcttcgattt tttcttctaa aagctcatcg atcgtttcat atagatgttg gaacccgtac
    20641 tctttttgaa ttctttcttt tgtttcttta tttcttgttg caaaataaaa atcaagtgtt
    20701 ccttgttttt tcgcataagt tggtaaatat gctttttctg cgatattccc tacaccgatt
    20761 acaccaatct tcatctactt tcctcctgga tcatttagtt actttcatct tacaccattt
    20821 tttactaaaa tgaggtacaa tagtatcgca aaggtaagga aattaattcg aaggagtgtg
    20881 cttttattga aatttatctc ttggaacgta aacgggcttc gtgccatcgt aaataaaaat
    20941 tttttagaag tttttcatga gttagacgcc gattttttct gtctgcagga aacgaaactc
    21001 caagcaggac aaattgattt agatcttcca ggttattatc aatattggaa ttacgcggaa
    21061 cgaaaaggct attccggcac agcgattttt gctaaaaaac cagcattgaa tgccacttac
    21121 ggaatgggta tcgatatcca tgatacagaa ggccgtctga ttactttgga atattccgat
    21181 ttctttcttg taacctgtta cacgccaaat tctcaaagcg aattaaaacg tttagattac
    21241 cgattagaat gggaagaagc cttttataat tatttggaaa atctaaaaaa acaaaaacca
    21301 gtcatcgtgt gtggggatct aaatgtcgct catcaaaaga ttgatttgaa aaactggaaa
    21361 acgaatcaaa aaaatgctgg attcactcca gaagaaagag cggctctttc tcgactgttg
    21421 gataacgggt ttatcgatac attccgttat ttttatccaa cccaggaagg tgtctactct
    21481 tggtggaact accgattcaa ttcaaggaaa aacaatgctg gttggcggat cgattacttt
    21541 ttgacgagca aagatttaga gccaggacta gctgatgcaa agatccatac ggacattatg
    21601 ggcagtgatc attgtccagt agaattagat ttgaaataaa gaggttgtga aaaagtcgtt
    21661 tagtttcgag tattaagaaa aattttgtga aaatggcttt ccacattttg cataaatttg
    21721 gcataatacc gagaaactgg cttttgaaca ctgtttatcg agagattgtg aaaaagctgt
    21781 cctgcatcaa gtaataagaa cagccaaaca aaaatagttc ctcatatttt tcgtttggtt
    21841 gggcttatta ccgcagatac aagcttttga acaccgttta ttaagaggtt gtgaaaaagc
    21901 tgcactgcat caagtaataa gaacagccaa acaaaaatag ttcctcatat ttttcgtttg
    21961 gttgggctta ttaccgcaga tgcaagcttt tgaacaccgt ttattaagag gttgtgaaaa
    22021 agctgcactg catcaagtaa taagaacagc caaacaaaaa tagttcctca tatttttcgt
    22081 ttggttggac ttattaccgc agatgcaagc ttttgaacac cgtttattga gaagttgtga
    22141 aatcagcgtc ctgacctgag tattagagaa acaaatggca aaatagttcc tcatattttg
    22201 ctattttttg agctaatacc gagggtcagc tgattgaaca ccgtttagtg gagaagttgt
    22261 gaaaaagtcg cctactttcg agtcgtaaga aatttttttg aaaatggttc ctcacaactt
    22321 tgcataaatt tgacttaata ccgagaagtc atgatcccca tctaactcca aatcacaagg
    22381 aatgagttca aaaactagct tttctcaaca aatattacat aaaaaattct atgttttttg
    22441 ttaaatttat ttgctttttt caaaagtatg ttacagtaat ttcccaagga ggttttacag
    22501 aaatgaattt tgttgccatg gattttgaaa ctgccaatca tcagccttat agtgcttgtt
    22561 ctcttgcgct agtcatggta aaaaatagcc agatcgttga tgaattctat acattgatac
    22621 agcctgagac tccttttttc tggcgaaatg tccaaattca cggaatccat caagaagacg
    22681 tacgcaatgc gccgaaattc ccagaagtct ggcaaactat ccaaccatat tttcaaaaaa
    22741 atcgtttagt cgttgcacat aatgctgctt ttgatacaaa ggtcttagcg ggatgcttag
    22801 attattatca tcttgaacag cctaattatc tttctttatg tacagtgaaa agtagccgtc
    22861 gcctgtttcc tgaatttcca aatcatcgat tgaacactgt gtgcgaaaat ttgaacatcc
    22921 aattagatca tcaccatgat gcattggaag atagtcgtgc atgtgcggaa atcctgcttt
    22981 atcaagaaaa aaaattcggg acagatccat tgaaaaaact tgtgactata aagtaaaaga
    23041 atacttatga aacacacaaa gaggtcgtga gcctgccgtt tcactccgag tcacaaggag
    23101 caatttcaaa aaatagcttc tcatgtttat taaatattgt gactggtgac cgaggagctg
    23161 gcaggagaac accgtttatt ggagaggttg tgaaaaagct gttctgcatc aagtaataag
    23221 aacagccaaa caaaaatagc ttctcatatt tttcatttgg ttggacttat taccgcagat
    23281 gcaagctttt ggacaccgtt taccaagagg ttgtgaaatc agcgttttga cctgagtatt
    23341 agagaaacaa acggcaaaat agttcctcat attttgccgt tttttgagct aataccgaag
    23401 gtcagctgat tgaacaccgt ttattcaaaa aaaatggact gcgacacgac ttttgtcaca
    23461 gtcccttcgt gtgtttttct gccttctcaa aaggatgaca gtttctcact cttttcctat
    23521 ttcttctatt caatcaaata actcatttta tatacatcta aaaattcacc tagatctgtt
    23581 cttgcccctc taggcatgac cgcttcgatt tggaagccca tttttcggta aaggtgtacg
    23641 gctctttcat tacgaacttg aacgtcaagc tccaatcgaa aaagtacacc catttccttc
    23701 gcccaactga tgatttcttc tagcataaga gtgcctagtc ccattcccca atattcctgc
    23761 agaatactga taccgacttc tcccacgtga gacaaacgaa attgactgtc tgccttgaca
    23821 gatgctgttc caataatcgt cccttcatag attgcaagca gcaataaatt attattgctt
    23881 tcgtatatat aatccaactc ttcttctaag gtttctggtg gtaacaggag ttctgcttca
    23941 tccaaaacta aaaattctgt ctccttatta acttgtccca tcatcaaaag aatgtctttt
    24001 gcatctcctg gcactgcttc ccgcaagatg atcccaactt cttcactcat gattttcagc
    24061 ccatttttct agaattcgct gtttgaaggt ttcactttgc tccccgtatg agattagttt
    24121 cacataccgc ttttctaaat ctgtatcact tttttctaaa atcagttcca aataatcctc
    24181 cggcagtgct tcttctaata gatttcccca ttcaacaacg gaaagcccat caccttcaaa
    24241 atattcatct aaccctaaat ctgctccgct agctgctacc cgataaatat ccatatgata
    24301 caacggaatc cgaccttgac tatattctct aataatcgtg tatgtcggac ttttgatcat
    24361 ttgcgttatc cctaatcctt gggcaattcc tttcgtcaac gttgttttac ccgcacctag
    24421 atcaccagtc aatatcagat tgtcacctgg cattgcggaa tgaccaattg cctctgcgaa
    24481 ttgttctgtc attgttaatc ctgatagttc gatcattttt catcttctcc cgctcttctt
    24541 tctttttgcc agtatatcgc gtaatgaagt ttttttaaag aaaaaatgaa ctagtcaaga
    24601 acagcagctg ctgtttttgg ctagttcgcg tgtatttgtt aatcaatcaa tgtttgtgct
    24661 gctgtgataa tcgataattt atatacatct tcttcatttg ctccacgaga caaatcagaa
    24721 accggtttgt tcaagccttg tagaattggt ccgattgctt caaagttacc gaaacgctga
    24781 gcaattttat agccgatatt tcctgactgc aattctggaa atacaaagac tgttgcttga
    24841 ccagctactt ctgaatctgg cgctttcagt tgtgcaactg aaggaacata agaagcatca
    24901 aattgcaatt cgccgtcgat catgtattgt ggcgctagtt ttttagcgat tttagttgct
    24961 tcaactactt tgtctacttc tggcgatttc gctgagcctt ttgtcgagaa gctcatcatt
    25021 gctacttttg gttcgatatc gaacaattct gctgtttttg cagaatctac ggcgatttca
    25081 gccaattctt gcgcagttgg attcacgttg atcgcacaat ccgaaaagac atatttttct
    25141 tgatctcttc cacgtaccat gatcatcgct ccgcttgtcc gactgatgcc aggctttgtt
    25201 ttgatgatct gaagtgctgg gcgaacagtg tcgccagtcg aatggatcgc tccagagacc
    25261 attccgtctg caatccccat atacgtaagc atcgtaccaa agtaattcac atcttttaaa
    25321 atcttttctg cttgttcttt ggatgccttt ccatttctac gttcaacaaa agtatccacc
    25381 atttcatccc acttatcgta attatcaggg ctgatgatcg taaagctaga tgttttgatt
    25441 cctctggcat gcgctgcatt tcttatttct tcttcgttcc ctactaaaat gggttccaca
    25501 agttcttctg ctttcaaccg ggcagctgcg cctaaaatac gagcatcagt agcttccggg
    25561 aaaacgattt tgatcccacg gcgaacaatt ttaaatctta aactatcaaa caattccaca
    25621 agatgacctc cagacgtttt tatatgtatt atcatacact attccagaaa aaaagaacag
    25681 tttattttat ctgtatcagt caaaaatgct ggaaaaatta agtttttcac atacaaagcg
    25741 aactgcacta taacaggaaa gcgctgtttt attacactgt ttcaggcagt tgccaatcaa
    25801 tcggttcttc tcctaacgca aggagcgcat cattcgtttt cgagaagggt ttggaaccaa
    25861 aaaagccacg acttgcagat aacggactgg gatgtggaga tgttatgatg atatggcgac
    25921 tcttatcgat cattttgatt ttttcttgtg ccggttttcc ccacaagata aacacgattg
    25981 gtttttcccg ttcatttaat ttttcaatga tcgtgtctgt taatctttcc caacctttcc
    26041 cgcgatgaga atacgcttgc ccttcccgaa cggtaagaac ggtgttgagt aaaaggactc
    26101 cctgtttagc ccatgacact agatttccat gttgaacagg tgcgattcca agatcatcat
    26161 aaagctcttt atagatattt cttaacgatg gcgggatctt tacgccaggt tgcacagaaa
    26221 aagataagcc atgagcttga ttttctccat gataaggatc ttgtcctaaa atcaccactt
    26281 taacttcttc ataaggagtc aattccaatg cttcatagat atgatacata tctggatgga
    26341 tcttttggga cgcatattct ttttttaaaa attctcttag atgcagataa taatcttttg
    26401 aaaattctga ggacaaaact tcttgccaac tgttatgaat gatttctttc aaaaactcca
    26461 cctcctaata aaaagaataa ctcacatttt cttcaatcac aagggacaat cttcaccctc
    26521 agcacttgat taatatggta aactaggaac aagaagcaga aaggaacgat aatcattatg
    26581 atcaaattaa ttgcatcaga tatggacggc acattattag atgcccatat gagtgtttct
    26641 cctgaaaatg ccgaggcgat acgttttgca aatgatgccg gtgttgagtt catggtcgct
    26701 actggtcgaa actatcaaga agctcgcgca gctttagatg aggtaggaat cgattgtgcg
    26761 atgatcactt tgaacggggc acaggtattt gataaagaag gaaattcatt gtttaccgtg
    26821 tcgattccaa ataatcaagc aatctctgtt ttagatattc tagatgctaa cggtatttac
    26881 tatgaagtag caaccaacga tggtctttat tctgaaaatc aagcgaaacg aattgaaagt
    26941 tttgcttcca tggtggctac ccatttacct caccttacgt ataaaatggc gattgccatg
    27001 gcctcagcta agctggagtt attgcacatc acatacgtgg acagtattcg tgctattttg
    27061 gaagaaaaga atctggaagt tttaaaaatt atttgttttc atacagaagg gccagctgta
    27121 ttaggtccag ttggaaagca gatttctctt ttaggcgatc tagccgttac ttcctctggt
    27181 caaaacaata tcgaagtgaa ccataaaaac gctcaaaaag gaattgctgt tgcccatgtc
    27241 gctcacgagc gtgggatttc tttagaagaa gtcatgacga ttggcgataa cttcaatgat
    27301 gtcagcatgc tgcaagtagc aggagtcagt ttcgcaatgg gaaatgcaga aatcgaagta
    27361 aaagattatg ccaaatatac aacggacaca aaccttgaat ctggcgtagg aaaagccata
    27421 ttgcgcgcga ttgcagaaga cttgtagttt tatctagaaa agagggatat agatgtcaga
    27481 atttttcatt caggaaaagc agcttggacg tgcaactcgg acaattgtca aaaacgaaaa
    27541 aggacattcc ctgtttttga tggttggtcg ctggggaaca aagggcgatg cattgtctct
    27601 ttatgccatg aatggcgatc tcgttgctca catcaagcag ataagcctga cattcggtac
    27661 gcgttttgag ctgtataaag agttcgaaaa ggtgggaacc atgcagaaaa tattcaattg
    27721 gcccggtgac ttttattata ttcgtagact tcactggaca gtccaaggtg atatctataa
    27781 tcatcaatat caaatccatc atttcaatca gcaaatcatg aaaatggata aagcaacact
    27841 tttttcagga gattactatg tattggatgt ctcaaatgat gaagatgctc cagtttgtat
    27901 ttgtattgct gcggttttag attactggct ctaccgtaaa gacaaaagtc gcgataagcc
    27961 tgtttcttac cgacttaact taagttaaaa agatgtacct gaaatgcgga aatacgcatt
    28021 tcaggtacat ctttttagat attcttttgc atatgatcat aaagatgacc actgatcatc
    28081 cgctgaccga caactttgaa gtcatggcgt tcgtataatt ttttagcctt tggatttttt
    28141 tcatccacac ttagaccgat gacggagcga ttagctttct tcgccaattt aggtaatgct
    28201 tctaataatc gcgaaccgat gccttgtcct ctaaaatctt ctgatacact gatagagtcc
    28261 aaataccatt cgttgggaaa cgtttcttta tcaatgaaca aacgtgtaga cgcatctagc
    28321 tgatatttct ctaagatagg taccagtggc tgatcgatga ttgattcttc ttcatctgta
    28381 taaccgtaag caactcctgc aactttaccg tctatttctt ctacgatacc tcgtgaataa
    28441 ctgtaacgat aatttggatc agtgattgct tcttctaaaa tctctaaagt cttttgttcc
    28501 cctgtctgct tcaaaaatgg cagttccata tcttttagaa tcactaagat caatggggcg
    28561 atttctggag catcttcttt tctcgcaaaa cgaatcatag tttcctctcc ttttctccat
    28621 tctaacatgc agaaaaagaa atcgcaaaat cgttatttta aaaaatcttc aatcttttca
    28681 gtaatgaaat aaccatgagt aacgattctt gccgcttcag ttcggcaata agggcagacg
    28741 actggcattt ctttatcatt atgttcgact acattattga cttcttcgta tgcaaatttt
    28801 tttccgcaat tagggcattt cattttttcc atgttatctc aacttccttt catctttact
    28861 ctcttagctt actcttatat tgtaaaaaag agaagcaata tccttcttct atgcagatat
    28921 ccatacctga cggtcctgtt ctccatctat taatcggact ttataataag gacgttcatc
    28981 tttgactaga agtgtccact ctttcacttt tgcttttttc ccgtagtagc tgactgcttc
    29041 cttcatcgct gcttgcggtt gtttgaactc ttccgttttt tctatatcaa aaagatgttc
    29101 tgcggccttt tccgtgtcat ttcgtacggt tgttttccca gtggatggat tgactgctat
    29161 gacttgtcct tcacaaaaaa actggtattc atatgttgca ttcgtaggat tctccaaatc
    29221 tttttcaact gcaaaatgaa tagcagatat gttatgttct tttgtttcgt tttttacgat
    29281 tgctgctgct tttttcaatg agatccgata ttcctggtca ctaatatcat ccatgtgaaa
    29341 agcggcattg agcagtcccg tcataccggt aatccctatt acgatgaggg cagcaacacc
    29401 aaacatcatt tttttcattc ttcattctcc tgtttctttt ttttaaagaa tatcaagaaa
    29461 tgaacgaatg aaaaatcgaa tgaaacgaaa aaaaagtgac aattttgtta tctttattcg
    29521 tgcagttcta atggcaatcc gtctggatca aagaaaaacg tcattttttt tcctgtaaag
    29581 gtatcttctc taatcggttc tgattcgatc cctaaggact gcaattctgc aattgtttct
    29641 tcaatatcgt ctactttgaa agcaagatga cgcaagccac aagcttctgg atagtttggt
    29701 cgttgtggcg cattagcaat tccaaaaatc tccaattcag cacttcctag tttcagatct
    29761 aatttatagt catctcgttc tttgcggtaa ttttctctga ttacttcaaa tcctaattta
    29821 ttaacataaa aatcacgtga tttctgataa tctgaaacaa tgatggctat atgatggatc
    29881 gttgtaaggt tcatatgagc actcctattc ttcgtttaag ctcggatcta tattaatctc
    29941 cagttccatt gtaaatgtgt cagattgaaa aaaatagctg tttttccttt ttataagaaa
    30001 aaaggcaaaa aaaacagaaa gtaggtcctc caagacactc ttcctgttcc caatataata
    30061 aatgaaagta agaaattata ttttcaagaa aacaaacaga aaattatcat aacacaaatt
    30121 atttataatt gaaagactag ttttttttca agaaaagcat acaatagatt gtgttagtaa
    30181 atacagaaca cactacattt agtgtcttaa ggagtcctca tacatgaagt catattttca
    30241 gtttttagct catcagctaa aaggctggcc gcaacaaaat tattatcttt tctttttcag
    30301 tcttggctgc caggtcatga ctcttgtcaa tagtcccatc acttggctgt ccgttattac
    30361 atttatcggt accacgcttg gtgtattgtg tattttatcc atcaatgcgg caaaatcagt
    30421 caacggtatt ttaggtattt tgtctgcgat ttgttttatt atcgttgggt tttcagcaaa
    30481 gaactattta agtatcggtg aacagattgc ttatatgatc acattggata tccccgtatt
    30541 gttaagtaaa gaatggaatc ataatatggc ttcaaaaatc cgaaaattca ctggaaaaag
    30601 ctggtttatc gcaatcatca gtactttcct tgtctatctt gtttcaggat tcctgattgg
    30661 tcgttataca gatgatcctc ggccgtgggt agatgccatt gctttttcta ttagcttgac
    30721 tgctggtatc atcagtttct tgcgttacaa caaccaatat tactggtggt tagcttcagg
    30781 gcttgctcaa atggtccttt ggtatatttc atttacgcat ggatctgcaa gtttggcgat
    30841 gttcgtgaac agctctgttt acttgctgaa tgatgtcctt gcatttaccg tttcaccttg
    30901 gtataaccaa aaagaacgtg aacgtatgca aaaaatggaa gaagaatact acaacgcaca
    30961 acaacacgca taaaaaaact gagcgtggga caaaagtaaa gaacactttt gtctcacgct
    31021 ctaaacacgt ataaacggcg gaatcagaag caactccttc ggaaataagc tgaaattcac
    31081 aaaaatttga aaagcaattt tcgtgaattt cttcttattt cttggagtta aacgcttctg
    31141 tcccagcctc tattttttat agtaattcct tcagatactt tcttgcctca tcattgaaac
    31201 gcagtgattc ttctaacttc tgataatatt ccaacgcttg tttctgagct tcagtaaaac
    31261 gataatgttt tcctttccat ttgtcgattg tctcttgcac atttccagat tggatatctt
    31321 tcactactag ttgccatttt tcttttgaga ctgtacggtc tttcttatca gcagattgta
    31381 tagcttctcg ttctttacgc aatactttta aaaaaccatt tctgactatc cgaggaatgc
    31441 tgtcgaagaa cccttctgta aaaccatagc gacaatattg cttccaaata aatagataga
    31501 tttttggttg gatgaatcgt tggtttttcg caaaatattc catctgagca gtgacttctg
    31561 gtgttcgttg acgttttgtc tttctcaaca cggaaataaa tgtttcaaaa taagcattag
    31621 gatgtactgg cacttcttca tatacgatgg attgccaatc tttacgtaaa aatgcgcgat
    31681 agttgatcaa gaattcttct acatccttta ctaattcttc tgcaaagtcg tcaaatagtt
    31741 ctttttttat ctgtcgcttt tttgactgcc cattgatgtg ttcacttatt ttcttgattt
    31801 cattttccaa tgcttgataa tccgctatgt aaatcggcat ttctacttgg cgaaattctg
    31861 cgagccgctg agctaatttt atatccggta aatatggctg tttcatccga cgattttggt
    31921 acaagacaaa acagtatttt tgccatagtc cttcaggaaa atcgatattc ttctgcttaa
    31981 gccataataa ttcgtctaag gccagatcaa cttttgtcat tccctgatgg atcgaagctg
    32041 ccactgtcgg agagacatgc aggtgatcgg caaagtggtt gatgcctagt tttaggatct
    32101 ttccggtttt tggcgattta acgatgtatt gcacttttaa ttctctacca cactcacaat
    32161 acaatttttg ctggcttcgt tttgttcgaa aaaacggatt gatcttgaag tcagaaaaca
    32221 cccaatctgt tgcagctaaa taatgttctt ccataaaacg agagctgatt agatatcggc
    32281 ggtgcttatc gactagttcc cgctgttttt tcgttaattt tgcatagatc tcccaacgtt
    32341 gactgcttgt gtattgttta gaaattttga tgggatagct tttgctgatt tcttttggaa
    32401 accattcttc aaagacggat tgccattctt ccacggctgt ttctttcctt tctaattaca
    32461 aaaagctggc tactaacata acgttagcaa ccagccagtg tttcttgcta aattagtgag
    32521 ttgttccggc atttccggaa atatcttctt tattttctac tgctgcttca actgcataag
    32581 tcaaagaaga agcaatgtct tctaaagaca tagaaggcgt acccactgga cgatcgatca
    32641 cttgatcggg tgagaatggc acgtggatga acccacctcg aattgccggg aattgtgttt
    32701 cgatcaaatg aagcaaacga tacatgatat cattgcagac aaatgttcct gctgtataag
    32761 agatgtacgc tggtagacca tgatcttgta cattttttgt cattgctttg attggcaatg
    32821 aggtaaagta agcggctgga ccgttttctt ctaaagccgt atcgaatggc tgatttcctt
    32881 cattatcagg gattcttgct tctgctagat tgattgcgac acgttcgaac gagactgctg
    32941 accgcccacc tgcttgtccg acacagatca cgacatctgg ttggtgctgt tggatggctt
    33001 ctttgactac ttgactgctt ttttcgaata cggtcggtac ttccactttg atgatttcag
    33061 caccgctgat ttcatctggc atttttttta ctgcttcata ggctggattc actttgtccc
    33121 caccaaatgg atcaaaacct gttactagta ctttcatctg ttgttcctcc gtccgattga
    33181 tttaacatat ggttatcttt tatcatacca ttttccttga acagcgtaaa taaaggaaac
    33241 aatagtttaa ataacataac agatcaaact taatatattc ttataaaaaa atagtgttcc
    33301 actacaatgt tagaagaggt tgcgacaatt attctgtcac aacccctctc ttctattatt
    33361 taaatagaat catataagca atttggaaaa ctagcataaa taacgcaata aacaactggt
    33421 ttttgatcac tccgtatttg tctttcatct ccagcatcgc tacaggcacg atattgaagt
    33481 tagcagccat cggtgtcagc agggtcccac aaaaaccgca agtcaatgca accattccta
    33541 ttaacgctgg attcgctcca tgactaaata cgaatggtgc accgatccca accgtcatca
    33601 cggtgatggc cgcaaatgca ttccccatga ttaccgtaaa tatcaccatg ccaagagcgt
    33661 aaatgatgat gccgatgttc acatttcctt ctggaacgat cgtacctact gcattggaaa
    33721 tcactgtccc aactccagcg cttgtaaata ccgcacctag agaagctaaa agcattggca
    33781 acatgcttaa cggccctact gtgcccagca tatctgctgc atcatctaaa aatgtacttg
    33841 gtcgattatc tcgagaaaag aacatcaaga ttagcatggc tgcaaaaaca ccgacgccca
    33901 cgccgactaa agcacctaaa ttggtaaata gagcaaacaa gatcgcaaag acaccgatac
    33961 tcaaagctgg aataaaaatt ttcattccta gtttgtctga cattttttcc atatattctt
    34021 ttgatggaag ccggctttct cctttgctga ctttcttagc aattgctggt atggtcatcg
    34081 caaagatcaa gccaccgttc acgattgccg gaagccatct tcctcctgca ataactaccc
    34141 ctaagaccgt ccagaaaaag gctgacccat aacgatgagg attggtttta tctgttaaat
    34201 ttcttactcc agtgtaaatc aatacgagtc ccatcacgat ataaaggatc tccagtaatt
    34261 tatcgcctaa taaaatatca ggatttgtaa aaaagtccat cttattgccc ctttcctgga
    34321 taatatttct tcgctaattt cttttcttta agatagaagt agacacttgc cacaactaaa
    34381 gccgtgatag ccactggaac ttccactaaa gcaagctgtc ccaatgttac gtcatatcct
    34441 agatctttca gtgttgattg gactagcaac gcccctgctc ctccgatgaa tagtacttgg
    34501 ccaaagaacc agcagacatt ttccatagct gaagccatac cttttagttc ttcttcatgc
    34561 ttaggatgga cttctaaccc ttttgattcg atggtcccca atgccatcgg taaaatgatt
    34621 ggacgaacaa atccagcaac tccaccaaaa ctcacgttaa aagccgcaaa gatcattcga
    34681 aagatcccat aaatatctac aatcatacca gcagatactt tcttgaatcg cttgatcaag
    34741 gaagccgctg attctttcag accatttctt tcaagcgttc ctgttgccaa cataatgatg
    34801 ataaaaatcg ccatcccgcg attgtttaca aaacttgtac ctaaaagttc taacattcct
    34861 tgaatgccaa gaccgccagt caaagctgta acaactaaag caaccattac gatcaatatc
    34921 gagtctaatt taaatgcaaa cccgagaata acaatcaaga cgcctaaaag gctaagataa
    34981 ttttccatat attttcctcc ataaaatgac aatatttttt taattataaa gcaaaacaca
    35041 taaaaaatat agttgttttc tcacgaaata gacactattt ttaaatattt ttcgttattt
    35101 ttttatcaca aaaattatct tacttattgt aaggtaaagc tttttttaat ttattgcccg
    35161 ataatatata gaaataaggt ctagttactg ttttttttaa atgattaata aataacaact
    35221 tctttctatg aaattgcaaa gcattcatct tcttttccgc taacgatata tccgtcagtg
    35281 cttggtacac tttactaaaa agtatgagat tgccgatatc tggataggtg tgctatacta
    35341 cagaaaaaga tatacaatct gccaccgggt aggataaaga ggatgatcat tccattaggt
    35401 ctttgaaggg atgattttcc tctttttgtg tattttttta tagttaagga ggaatgtaag
    35461 tatggcatgg atggaattaa tcatagcagg aattttggaa gtattctggt caacgatgat
    35521 gaaatggagt gatggttttt ctaaaatcaa ttattctttt tacacagtga ttggcatgat
    35581 tgctagtttt tactttttgt caaaggcaat caaaagtttg ccgatgagtc tctcttatcc
    35641 tatctggaca gggattggcg cagttggttc ggtcataatt ggtgtggtct tgtttcatga
    35701 taagctgaat ctttccactt ggttctttgt ggggatgcta ctcatcagta tcattggcat
    35761 caagattact agcggccact agacacttgg aataagtact gatcagaaaa aataagcctt
    35821 tttatttaat attcaatttt tttatgaaaa aataagaaat aagtccaatg acctagcgac
    35881 ttctccactc atcaggtgta tgcttgtact atctatagaa aaggagtgaa tatttttgaa
    35941 aagtctttcg gtccaagaat tatccaagaa ctttggtcac aaacaagccc tcagcgatgt
    36001 cagttttagc ttatcccctg gcaaaatcgt tggattagta ggtcctaatg gcgctggaaa
    36061 aacaacgatc atgaaagcta ttttaggact gatccattac tcagatggaa caatctgtat
    36121 tggtgaaaat gagatttctc cctctagtca taaagggttg gaacaagtag gagcattgat
    36181 cgaatacccg ggtatctatc cattcttaac aggctatgat catctgaagt tattctctga
    36241 aaccaacgat gtatctgcta tcgacactat cgtgaatcag ctcaagatgg aaaagtacat
    36301 tcacaaaaaa gcgaaatcct actcgttggg aatgaaacaa aaattgggaa ttgctcttgc
    36361 cttactgaac catccgtcta tcgttatttt agatgagccg atgaacggtt tggatccaca
    36421 agcaacaaga gatgtgcgaa aaatcattac cgacttggct actcagggca cctctttctt
    36481 gatctccagt cacttactca gcgagcttga aaaaatggtc gatgagctga tcctgatcaa
    36541 tcaaggaaag atcatcaaac aatgtacaat ggctgaattg aaccaaacag cgcaagattt
    36601 catcgttatc tctacaacaa atgatctagc tgctcgaacg atcttgacag aagctggata
    36661 tactttggaa gatcctgata aaatcaagct tttaaaagaa aacgaagaat tattaggaac
    36721 cgtgatccag ctattgtctg cacaaaatat ccatgtgaca gacgtccagc atctgacgaa
    36781 tgatttggaa tcttctctat tggaaattct ggattcagta aagggggaag aagaaaaatg
    36841 acattgcttg taaaacaaga attatttaaa ttgatcaaga aaaagtcaac tgctgtttta
    36901 tctgttctat tagttgtttt gctcatagga acagcacttc tagccaaaaa atacacgacg
    36961 atcattgatc cagttgaaat gactgctcag ctttttagtg ccacatcttg gattgtcttt
    37021 atcatgattg cagctgcaag cacgatcatt tcgatggaag cacaatatgg tacattgaaa
    37081 aatctccttt atcgaaagta ttctcgagga gaaatattag taagcaaatg gatcacatta
    37141 gttatttatt ctgtttattt atacctttta gctattattg tcactgtgtt gatgaaactg
    37201 attcttttcc cttcgatttc cttcacggag aaggtttcta ctggtcaaac actgatccaa
    37261 agcttgttca cttatacttt gggtagttat atcggtttat ggctgatttt aagtttagtg
    37321 ttgatgattg cttgctttat caatagttcc ggcgcatcca tctcagcagg aatcgtcttt
    37381 tattttgctt cgtcaatcat atctggtatc cttattgcac tcatccaaaa atgggagtgg
    37441 atcaaatgga atccgatcag tatgttgaat ctgcaaaacc aaattggaaa cgaagagatc
    37501 atgaagcaat tgactcatct ttctactaat caaatgctat tcggtaattt agcttacatc
    37561 gttttgttct tagcattagg atatctcgta tttaagcgaa aaaatgtatg atgactcatc
    37621 aaaaaagagg ctgtgaaaga gacgttcagc cttattgccg attggctgtc tcttaaacac
    37681 cgtttattct gaaaaaggag ctgtgacaac atttgtgtca cagctccttt cctagtatgt
    37741 ttttgaataa acgacaggct cacaacctct ctttatactt cttttatact tctatacgtg
    37801 aagcatccca gtggcaaata aaaccattgc aatcactccg accatcgtca cacctataag
    37861 taaaatctta tctaagtgga tatgttgtac aggctcgttt tgctccttac gtgctttgag
    37921 gtaaaaataa atgcctggca agaaaagaac aagaacaagc attacttcat taaaggctac
    37981 gactagcata gcccatactt gaaaggcact tgctaaaagc cctactaaaa attggaccca
    38041 ttctttccgc tgataagaaa gtttcatttg gtacaatcct aagaaaagcc acgtgaagaa
    38101 aatagctgct gtaccaagtg tgtaagcaaa gttataagca ctgtcagtga ataataatga
    38161 aagtaaaaag acattcgtac ataacgtcgt caatacgata gcataagttg gtgccccatt
    38221 tttgttgagt tttccccatg ctttaggcaa aagtccgtct tcagccatgt ttcccattgt
    38281 ttcaatcggt aagatcgtcc atgagagcca aacaccaact aaagaaatga tcaaaccgcc
    38341 gttgatcacg actgctcccc atttaccaac catcatttca aacacatagc ccatagcagg
    38401 ctgcgccttg atcgtttgca gctgattcat cgtcattgtc ccatatggaa gcatggaaac
    38461 caagacgtaa ataataatca agccgaatat ccctagaatc gttgctttcc caacatctga
    38521 ttgttttttt gctcgtgaac ctacgacaga ggctccttca ataccaacaa atacccaaag
    38581 catcaccatg atgcaactca atacttgact ggaaaacggg atcggctgtc cattcgcatt
    38641 caatataatg tcgctagaaa agttatcaat gaattgttgg atcgaaaacg tgctgatagc
    38701 tactacaata aataaaaata atggcactaa tttacagaat gtgacgatag cattgacgaa
    38761 actagcattt tcgactcccc gattcactag ccatgcatat ccccataaaa agactgtact
    38821 catcacgatc gatgccagat tttgcccacc ttcaaatact gggaagaaat atcctaatgc
    38881 gctcatcaac aatgttgcaa aagctacgtt gcctaaccag catgtgagcc agtaacccca
    38941 accgctgata aaaccagcga aacggccaaa accttcttct gcgtaactaa agatcccgcc
    39001 ttttaaatct ggacgttttt tattgatatt attgatcgac aaggagagca tcaacattgc
    39061 tgttcctacg agtacccaac tgaaaatagc tgggccgcca gccgatccgg agatgtccgt
    39121 cataatacca aatacgccac ctccaatcgc tgaaccaatt actaaggcag caagtggaat
    39181 taaaccaatt ccttttttct gttgctctgt atccatgtaa gcatcctcca aaataaaacc
    39241 gcttttatca aaaagtataa caaacctttt ttatttttac ttaattaata aaaactttaa
    39301 tagaaatata attctaccgg cttttttctc attatacaag caaagcgcct agtccctttc
    39361 caaattacac caccaaaaaa cttaaaaaag atgctatact aaaaggaaag aattggagga
    39421 tgatccatga acattttata tatatcgatt tcaggaaata cgcgtgcctt tgccaaacat
    39481 ctagcagaat atgctgaaaa aatgcatgca gaagatcctg tcaatcctga agttacttta
    39541 aaagaaatcc atgaaaatag tgattttacg aaagaaacag aaccattttt tactttcgtt
    39601 cctacttatt tagacggcgg aaatggttta gataacggtg atacagaaat cttgaccgaa
    39661 acgatgcgtg aatatctgga acatgaagac aatcataaac tttgtcttgg tgtagtcggt
    39721 agcggaaata aaaacttcaa taatcagtat tgtctaacag ccaaacaata tgcacaaaca
    39781 tttggctttc ctttcttggc agattatgaa ttacggggaa caccatctga tgtgacacga
    39841 atttatcaga ttttagcaga aaacaataaa taataaaaaa gaagaagctg aaaaatagat
    39901 ttcagtttct tctttcgttt ctattgtttc tatcatatta agctttgaca tccatcacag
    39961 gtgcttttgc ttttgcttta cctgtttttt ccaagacaaa gttttttaca cgatccatat
    40021 tggttaccaa gacgatcatg gatgtttctt tgcctgctgc tttgatcgct tctaagtcag
    40081 cttctgctac aagcgtatca ggtgtcactt gctgcccttc tgttactttc acatcaaatg
    40141 gcgtaccgcc taagtcaact gtgttgattc ccatatgaag caagatttct aaaccatttg
    40201 gcgttgtgat cccaatagcg tgtttcgttg ggaagacaga gctgactacc ccagtaactg
    40261 gagaatagat atgtccgttt tctggttcta caaagtagcc ttcacccatc atcttttgtg
    40321 caaaaactgg atcacttgct ttatctaaag aaacaactgt tccgtcagca actgatgaga
    40381 ggatagtcac actttcagct gaagtttgag gtactacttt ttcaggcact tcatttactg
    40441 tggctgtttc agtcgctaat tcttcttttt ctaaacggtc tttaggaata ccgaagaaga
    40501 atgtagcaac gaagccacca gcataagctg ccaataatcc aaggatgtag cctaaccatt
    40561 taccgtcaga gatcaatggg atcaaagcgg ctcctgaagg tccaatagcg atagccccga
    40621 catttccgat cattccgatc actgccccgc cgatacctcc accgatacaa gcagtaataa
    40681 atgggcgtcc tagaggtaat gttactccgt aaatcaatgg ttcgccgatt cctaggatcc
    40741 cgactggtaa agctcctttg atcatttctg ttaattcttt atcttttttg cagcgaatcc
    40801 ataatgccaa tgctgcaccc acttgtcctg caccagccat cgcaagaatt ggaagcaata
    40861 gcgtacgacc agtttcatca atcatttgca catggattgg agtcaaaatt tgatgcagtc
    40921 cgaacataac catcggcaag aataatgtgc ctagaacgaa gccggcaaat gctccaccaa
    40981 cgccaagtac ccagttgatc ccaccgacca tgccatcaga aatgaaacct gctaaaggca
    41041 tgatgaagaa aatttcaatc agaccgatgg caatcaatga aagagttggt gtaacgatga
    41101 tatctaccgc atcaggtact actttatgca gttttttctc aacgattgac aatagccaaa
    41161 cagcgaagat gacacctagg atcccacctt gtccagctgc aagagcttca ccagtaaata
    41221 agtttttcag tggtgcttcc ggattcatcc ctgtcagcat cacaacggcc ccgataactc
    41281 caccaagagt tggtgttgca ccaaaaactt gtgcagcatt gatacctgta tagataacta
    41341 ggtagctaaa catcccgttt ttcaagatgt tcatcacatc gatatattgt tgccatgttg
    41401 ctgcatcaag tgttccggct gtgactaagt ttgctaaaac tgcggcaatc cctgccacga
    41461 tcccagtacc gacaaatgca ggaatcattg gcacaaagat attagaaatg tcttttaata
    41521 ccgatttgat tttagatggt ttttgtttcg atttttgtgc cgctttcatt tcttgtgccc
    41581 gttcgtttac acggtctttt ccagatgctg atgaatttgc tgtagctgta cttacagaag
    41641 aaagtttttc tcctaatttc acgcctgcca aatcaaccat ttgctgtgct actttgttca
    41701 ctttcccagg tccgatgatg acttgaagct gttcatcttc tactacacca agcactcctg
    41761 gaatcgcttt taattcagag acatttacaa gatcatcatt gatgatcttc atacgcacac
    41821 gagtcatgca gtggacaatg ctttctacat tgcccatgcc gcctgcccct ttataaattt
    41881 gttttgccag ttcttccaaa gtcagttcgt tttttgccat ggtcttttcc ccctcataag
    41941 gtccctttta caaatccgtt tgcttcagct aattttgctt gagcttcctc tttatcacta
    42001 tttgtcaaaa tcatgacgat agccagctta acattttgat ctgcttcttc aaagtacttt
    42061 tcagctgttt cgtaatcagc ttctgtcgct tgcatgatga ttcgttttga gcgttcgatt
    42121 agtttttcat ttgttggttt gacatcgacc atcaagttat tgaatacttt acctatacca
    42181 atcatactga tagtagaaat catattcaag ataagttttt gtgctgttcc tgacttcaat
    42241 cgagtagagc ctgtcaaaaa ttctggacct gcatcgactt cgattgggaa atccgcgtgt
    42301 ttactgattt cggcttgttt attgcaagaa atcgttcctg tgacagcacc gatcgatttt
    42361 gcgtaatcta atccaccgat cacatatggt gtacgaccgc tagctgcgat accaataact
    42421 atatcatttt ttgtcaaatt cagcttgatt agatcttctt gccctagctc ataagaatct
    42481 tcggcccctt cgacagctac agtcattgct tcttctccac cagcaattag acctatgacc
    42541 atttccggtt ctacaccgaa tgtcggtacg cattcagcag catctaacac acctagtctt
    42601 ccacttgttc cggctcccat ataaatcaga cgtccacctt ttttaaagga ctcaatcgtg
    42661 ttagcaatca ctggttcgat acttgtcagt tctttttcaa ccgcagcggc cactttctga
    42721 tcttctttgt tcattagttg aacggcttga gaaatactca tctcatctaa tccaaaagtt
    42781 tcttggtttc tgcgttccgt tgttaggttc tctaaattga ttttgctcat ttttatcttc
    42841 cttcttttct tataaattga tagttcatac cagctttgat ttggttgatc aatggtagct
    42901 cttctttgat aactttagct actacattca ctttttcatc cgctggcaaa tcatatttgg
    42961 ttaattggat ctcacccata tagcgcaaat acttttcgtt atctaaagta atagaccctt
    43021 tcatacgcgt agctgtattt cttgctggga taggcggaat ctctcgaaaa cgtgcatcta
    43081 cgcttcgtat gacatctctt gcatcgtctt gccgattcgt atgcttccct aatatatatt
    43141 cgtaaaattc ttcatctaca ggttccgtat ggagcaagac tgtctgttct ttttggaaag
    43201 aagcaaattg ctcctgaacg ttttctgaca gacctgcatc tccgatgtaa acaatatccg
    43261 tgttacttgc taatagatct agagcgcctg caagaggatg gatccctcga tgttcttcca
    43321 aagttggcaa tccttgatat agtgggcctc tcaactctgt atctcctggt acaaaacctt
    43381 ggacaaggag accttgaatt ttgagccatt gatttttttt ctgataccat tctttgtcca
    43441 gccctgtttc gggacgtgga taataattat gccaagcttc aatctgtgag aaatcagctt
    43501 ctgcttcttt caattcatcg atatctttag gcgtgatcgt gctagcattc aaactgattt
    43561 tcaattgatg tgaccagtcg gcaatctgct gattggaaat atgataatcc attcttaaac
    43621 ctgttacacc aattgctttc aaaggcgtta gatcttctaa tgaaaaaccc gctcgttcca
    43681 atgcctctcc tgaaatatcg accatcaatt ctagtttatt ctttttcgct tcgcttccta
    43741 gttcgatcaa tcgcttttga tatgccgaaa catcatcttc tggtatatgc atggaagtga
    43801 aaataccgac aaagccattg gatgccattt ggcggatata ctgtttcttc tcttctgaca
    43861 aagaatcgtt cataaatatt gaaaagccaa acatattatc cctctttttc tgtatccgtc
    43921 ttcatttcta tgactagagt atatatctaa agaaacaaaa tttcaatact tttattaaaa
    43981 taattaaatt tcatttctaa aggttgagtt tatattatca aaagaattgt cataacctaa
    44041 aaaaggcact gctaagcaaa agcagtgcct tgaaatattt tatttaaata acacaaaaac
    44101 ataattactc ataagaaacc aattctgtat tatctaccat gaatgtaaag aacccctcat
    44161 taggcatcgg atgaaaataa gcattgatca ctcttatcaa ggcattatgg caaactaaca
    44221 gatagacatt ttcttcgtct tcgatgcatt ctttcaataa aggaacgatc cgtgcataca
    44281 catctaagac tgactcccca tttgggaatc gtacagcgaa cgctaaacgt gctttttgaa
    44341 agttctcatc tttgcttggc agtccatcat aatccccaaa atccatttct accaatcgtt
    44401 catcaacggt cagcggcaag ctgagacgat cagcaactgc ttgtgctgta tctcttgctc
    44461 gttgaagagg ggaatggatg attttcgtga ttggaacagg caaatctact accttttctg
    44521 ctagtttctg tgcctgcatc tgtccttttt cagtcagcgg cacatctgcc cgtccgcaaa
    44581 ctaatccttg tgcgttccaa gttgtttctc cgtgtctcgt tacataaagc atgtgattct
    44641 ctccttcgtt ggcaaagttc cccttaacca taccttgttg ttcttgagat tacaagggtt
    44701 agattctctc aagagaaata atctcagtag atactttatc caggaaggtt tgatcatgtt
    44761 ccactagtaa catggcaggt ttcacgttca agatcagttg ttctaattgt tcttgattga
    44821 agacatccaa ataattcaat ggttcatccc atgtatatag ttcagctggc tgtgataaag
    44881 atttagccaa ttccactttt ttccgttggc ccatactcat ctgctcgatc ttgttatgaa
    44941 aaacatctct ttccatccca agctttcgga ggttgttcaa aaatgcttgg tagtctactt
    45001 ggtttttctc tgcaaattcc gccaacgttc ctcgattgtc ttcataattt tggcttgcat
    45061 aactaatgct cagatgtttt ggctggtatt tttctcctat aaccttgccg ttgaatgccc
    45121 ccagaagata atggataatg gatgactttc ctgcaccgtt aggacctgaa atcgccaccc
    45181 gctgatgagg ctcgattgta aaatgaattg gctcgaataa cagattttca taccctaatt
    45241 gaagatcttc tacgcttaaa agtcgcttat ggtgagacgc ttggctattc atcgtcaaag
    45301 aatcgatata ttcgatatct tttaatagtt tttctttctc gctgatctgg gtctccatcc
    45361 gattcacgat tgctttggat cgtttcatcg tccgtgcagc atcagcaccc actgctcctt
    45421 tattcactcg tctagattca gtatcgatga atccgacttg tttctttgtt ttatctcctt
    45481 ctcgggaacg agaccattcg gctttttcag ctgctgtttt ctttagccta ctgacttctt
    45541 ttttcaattt ttcattttga gccatttcaa attcatcacg aagttttttc tgttcttcat
    45601 agatagagaa attcccttga taaagttcca gttgactttt ttcgattgct aaaacatggt
    45661 ccactacttc atcgataaat ccccggtcat ggctgaccac gatgaagcct tgttttttct
    45721 ttttcaaata agccgctact tgttttctac cagagatatc caaatgattc gttggttcat
    45781 cgattaacgg gaaatgagtg tcatccacaa ataaaagtgc cagtaggact tttgtcttct
    45841 ctccccccga tagtgtgctg aattctctcc ataagatttc aggatctgtt tgcatcaatt
    45901 ggagctctct ttcgatttcc catatctcaa aatccgtaat atcatttaac acgtaatagg
    45961 ttaaacgttc tttatctttt gtctgttgcg ggaaataggc aaattcttgc tgatggatta
    46021 cttgcccttg ataaggtagt ttgttttgta gaatattcag taaagttgtc tttcctcgac
    46081 cgtttcgtcc gataagtcct agtttccatt gtgtgtcaaa atttagattt gcttgttcaa
    46141 ataataatgt gccttggctg tcgtagccga atgtcagatt ttttatttcg attttagaca
    46201 ttttccatca cctcgtaaaa aaagaccagt cctattttca gaactggcta aagaggatgc
    46261 aagggttgga tacacacaaa aagacccata catcgaaaaa accaagccaa tcccgaaaat
    46321 ctgcacactg cttccttgtc tccacaaggt acagtctgaa tgcagctttc atcaatcgac
    46381 ttaatttttc aatgcacgga tccctcactt tgtcctatat ttgaaattac gatagcataa
    46441 agaaaatgat tttgtcaact acttcgggag gatggtgaaa aatctgctaa gtgtctgtcc
    46501 taagattttt gttttttcta atgtttgcct gtgttccatt gcttcttcta aacctattgg
    46561 acccaaatga atacttaaga caattgggag aaaatcagaa agtccttcta gctcttggtc
    46621 tctacttccg caaatagcga ttattggttt tcgatatttt tttgcaagca ctgctacacc
    46681 gtatggaact tttccgtgga tcgtttgctg atcgatccgc ccttctcctg taatgatgac
    46741 atctgcttgt tcgatctttt tttccaatcc agtgatttgg ctgactaaat cgaaaccaga
    46801 aaccatcttc gctcccaaca aaaaaagggc tccaccaata ccgcctgctg ctccacttcc
    46861 tggaatatca tctaaatcca cctcccagaa atcttttatt tgctgagcaa tctttcctgc
    46921 ttgtttatct aagaaagcta gcgtcgtatc tattcctcct ttttgtcttc caaattgcca
    46981 agcagctcct tgttgacctg tatatggatt ggtaacatct gcagcgataa tcaattttac
    47041 tttagaaaca agaacgtttc ttcgatcaaa atgaagtttt ttagtagata ataaaggatt
    47101 tccttctgtg tacccttcta aagaagcacc caaggattgg agtaatccta gaccaccatc
    47161 gctacacccg cttcctccta aagtgacaat aatttgttct acttcttgaa gcagtgcatc
    47221 tttaataagt tctcctaagg cataactgga agcaagtcgg atagtttgat ccgttggttt
    47281 atcaagtaga tctaacccca atgcttgtgc agattcgatg actgcggtgt tttttccttg
    47341 ccaagttgtc aataaatagc tgatttttcg ctgacggaat aagagatcca tcccatcaat
    47401 ggtacgccat gttcccctga gcgcgtaata gattgcttct gcagtatttt ctccgccatc
    47461 tgcaatcggc acattgattt ttcttccttt acgatcttcc cagccattta gaactgcctg
    47521 atttagttca aatgaagaag cacttccttt aaatgaatca attgccgcca aaatatccat
    47581 ctgtatccct cactttcttc ttaagtaaga cacttttttt catttttttc aaacaaaaca
    47641 atgctatttt cttccatttt tctatatact aaaagggaac tcattgaata aaggagagaa
    47701 aaaacatgaa aatcgcaata gctggggccg gagcaatggg cagccgaatc ggattgatgc
    47761 tacatcaaag cggaaatgag gtcctcttga tcgatcgttg gcctgctcac attgaagcca
    47821 ttcgtacaaa tgggttgatt gctgacttta acggtaaaga agtggtcgca aaactgccaa
    47881 tctattcacc agaagaaatc atcgaaagca acgaacacgt ggacttgatc gtagcattaa
    47941 caaaagccaa tcaattagat gatatgtttt gttcgatcca atccattatt actgacaata
    48001 cttatgtttt gtgtttacta aatggattag gtcatgaaga tgtactggaa aaatatgtgc
    48061 caaagaaaaa tatcttattt gggatcacga tgtggacagc tggtctagct ggtcccggaa
    48121 aagtcacatt gttaggtgat ggagaaatcg aactagagaa cttggaacca gaaggcgaag
    48181 catttacaaa aaaagttgta gaagtctttc aagaagcaaa tttaaatccg atctatagcc
    48241 ataacgttcg ttattccatt tggcgaaaag cttgtgtaaa tggaacattg aatggtttat
    48301 gcacgatttt ggattgtaat attgctgaac taggcgcgca aaaagcggca gagagcatgg
    48361 ttcgaacaat cgtatctgaa tttgcttcta tcgcagcaaa agaaggaatc atactagatc
    48421 aagaagaagt gtaccaacat attgcttcta cttatgatcc tgacaacatc gggttgcatt
    48481 acccatctat gtaccaagac ctgatcaaaa accatcgttt gactgaaatc gactacatca
    48541 atggtgccat ttggcgaaaa ggacaaaaat atgatattgc tacaccatat tgtgcctttt
    48601 tgacccaatt agtccatgca aaagaaggaa tccttggcgc agaataaaag gctctctgat
    48661 gagaatcagc tgaatcagca gctggttctc tttttttaag cccaataaaa gatcaaaaag
    48721 aaaacacaac tctcatgatg ccataagaat tgtgcttgtt tgtttcagta cataatctct
    48781 tcaaaatgta ggttttttat ttgttttcaa cagaggagag gtcatattcg tattgctcat
    48841 aaatagtgga atcgttagtg ataaatcgtt ttgcccaatt ttctgcatca taaaattcca
    48901 atagctctga taggattggc ttaaatggtg tatgcagaaa ttccggtaat tcatctaaat
    48961 cacgttctcg aagcaaaaaa atattttcag gacgataaaa atgataatga gcaatcgctt
    49021 gattatccgt cactagtttc ttttgaaaat acatggattc aaatgtccgc aaagtcactc
    49081 cttgctgacc ctcccgcaac agttccagaa tcccgcgcga ttcccctgtt tttttcaggt
    49141 actcttcata agtaagatat ccaggttgtt cattccctcg atgtggaaga atgaaatagt
    49201 tggtcgtaac atctcttttt ataaattcct gcttatagct ttctgctcgt tcttttctcc
    49261 cattattcgt tgcaccaaaa aatagatccg tctttggttc gctagaagaa aaattcatat
    49321 gtttcgaata aaatgaacta ttatgtttca gcccaagttc ttttgcttcc aaaaaatcaa
    49381 aatgataaat ctcatcgatt gccggttcat cttgtgcctg cttcagcatc gcctcgtgtt
    49441 ctgctttgaa gtgattccaa aaaaataaca caatttttgc attggtaaat gggcgcacgc
    49501 gtcgagccat ctccatatca aatccataat ctaaaaaaac gatcagctga taatttgcca
    49561 actgttgtct agctgattta atgaattccg actgtagtaa atcttttccg gaccaaacat
    49621 ctaaagagcg gatggaaggc aaaaaataaa gtgatttatt ttttgcaact agcagtacgt
    49681 catttttgtt catcttttcc gcctcacttt ctctgtcact ttttcctatg atagcctgtt
    49741 taaatagtaa aaagccagta aaacgtttcc tatatttgta tgaaaattta acatttgtat
    49801 gaaaatatga tgaaataaat cattcttcta ttaaaattcg cctaaaagtt ttctgaatag
    49861 ttgtaattgt ctgaaaattt gttatcatta gtcattgtta aatattgcta tttattctta
    49921 atataaattt tgattgtgaa tttaaaagaa agaggtcatt tatggaagat aaaaaattga
    49981 aaaaacaact tagctccaga catatcacca tgttagcttt aggtggagca atcggtgcag
    50041 gtctatttaa aggaagtggc gaagcgattg ggatcgccgg cccttctgta ttgattgctt
    50101 ttttgattgg tgggctgatt ttatatatcg tgatgaaagg tctgggaaaa atcgttttaa
    50161 gcggtggcga cacgcatcac ggattatctg gtttgatacg cccttatcta ggtgctcatt
    50221 ctgctgattt tactgattgg gtctactggt ctatgtggat tatcaatatc atcgctgaag
    50281 ctgttgcagc tgcttccttt ttgcagttgt ggttcccgca cattccagcc tgggtatttg
    50341 tttttatgtt ggctgtttta actacgatca tcaatcttta ttcggtacgg ttattcgcag
    50401 aaacagaata ttggctggct tttgctaaaa tcagtgtcat tatcttactg atcatttttg
    50461 ctacttatct tgtcggtcag caaatgttgg gcacaggcgt tttccctacc cttcagcaat
    50521 tgactgacca tggtgggttt actcctcatg gtatgaaggg aatcatcagt tctttgcttg
    50581 tagttatcta ttcttacggc ggttctgaac tgattgctat cacggtaagc gaagcagatg
    50641 atcctaaacg tgcgattcct aaagcaatca aaggtgtcat gggaagaatc atttcctttt
    50701 acatcattcc tttgtttttg cttttgattc tttttccttg gaatacttta gcaggcacga
    50761 atgtcagtcc ttttgtgatg gtatttgaaa aaatgaatat cccatttgca gcggatatcg
    50821 tcaattttgt gattgtcctt gctttgttct catctatcaa ttcgggtgtg tatgcatctt
    50881 caagaatttt gttcttccgt ttgaaggatc gaaaaggttc ctctagaaaa ctagctgttt
    50941 taaacaagca tcaagtaccg caacgtgctg ttttattttg taccagtgtt ctttatcttg
    51001 gtgtagctct ttcttatttt gtcggtgaca aattatttgg ctatctggca ggttcccttt
    51061 cgtatacagt attattgatc tggatcatta tcagtgcggc atcctttgta ctggcactaa
    51121 gaaaaggaac attatgggat aaaggaatca gcttttttgc attagctgtc ttaggattga
    51181 ttttccttgg tatcctgttc acgaactcca ttggggtaac tgtattgact ggcctgcttt
    51241 acctgttcat ttatttcagt tatcaaaaaa agaatgatgc gttcgtattg acgaatgaat
    51301 gaaatcgata gaaaatttta ttttatttat gtggaataga tggagctatt gaagaaagga
    51361 gttgtgacaa aagtcttgtt gcaactcctt tttccgaata aacagtctca tgacctcttg
    51421 gtaaacggtg ttcaaaaacc ctctgtgcaa aataattgat tgttctccat gctcatgaca
    51481 tgatagaaga aaggaatgaa aaaaaggagt ttgttttaaa tgaaaaagta ttggaagttt
    51541 ttgttgatga tcggtgtttc aacggtagtt atgtttggta tgatgtactt gaatgtctat
    51601 gcgctcgatc atatcttctt cagtcgtaca cgagtattca tggcgttgat gatgggtgca
    51661 gtcatggcag tcatcatgct gttgttcatg tggaaaatgt atgaaaacaa aaagataaat
    51721 gttatgatct tagccgctag tcttcttgtt tttgccggtt ccttgtttat ggtacgaagc
    51781 caaactactg tcaacgacac agcttggatg aaggccatga ttcctcatca ttctatcgct
    51841 atcctggcaa gtaaacgagc tgatttaaaa gatcctgaag taaaaaaatt agcggaagaa
    51901 atcattcagg cacaagaaga agagatcgac aaaatgaaaa aaatgatcaa agaaatggaa
    51961 tgaccattat ccgtccaaat aaaaaaagag gatgttccag aagttatcag cttcaagaaa
    52021 taagaagaag ctacttctgg aacgccgtga ataaggggtt gtgaaaaagc tgccctgcat
    52081 caagtaataa gaacagccaa acaaaaatag cttctcctat ttttcgtttg gttaggctta
    52141 ttaccgcaga tgcaagcttt tgaacaccgt ttattaagag gttgtaaaat cagcgttctg
    52201 acctgagtat tagagagaca aatggaaaaa tagttcctca tattttgcca ttttttgagc
    52261 taataccgag ggtcagctga ttgaacaccg tttatcgaga ggttgtgaaa aagtcgctta
    52321 gtttcgcgta ttaagaaaaa ttttgtgaaa tggctttcca catttttgta taaatttggc
    52381 ttaataccga gaaactggct tttgaatacc gtttattcgt aaaagggatt gtgacaaaag
    52441 tcttgtcaca atcccttttt atgtttttat tgttctaatt gcgctgtctt gcttactgct
    52501 tcttgcggtt tcacaaattt ttttgagatt ccccaacctg tgaaggcact gaccatcgaa
    52561 aacacaggag aaagcaaact gaaaaatacg aatggcaagt aagtgagtgt aggaatacca
    52621 aatgtacttg ctacgaaact tccggcaatt ccccaaggca ctaagtagtt gattactgtt
    52681 ccaccatctt ctagcgttct acctaataca gttggatcaa atcctgcttt ttcataagtt
    52741 tctttaaatg cattaccagg cagaataaca gataggaatt gttcaccaat aaaaatattt
    52801 actccgatac ttgtcatcaa tgttgtaaaa atcaaatttg gtgtgttcgt catctttctt
    52861 gatactcgtt ccatcacggt tgagatcaag ccaaattcga tcaacaatcc acctaatgac
    52921 aaagttagaa taatcaatga cacagtaggc atcatacttt cgattcctcc gcggctaagc
    52981 agtgaatcga tttgttggtt tccagtattt gaaacaaacc ctgattcgat gaccccagcc
    53041 aacttcgtta aggaagtttg tgggttttga ataaaaatca ttcctactgc tacagcgata
    53101 ttcaacaaaa tcgttaaaat tgccggcacc tttttccatg cacacagtaa cattaaaaat
    53161 aaaggaatca gtgaccagat tgaaatagta aagtttgctt ctagaacatc agtcacttca
    53221 cgaatagatg aaagacttgc ggctttactt gtgtgtccta aaatcatgaa taaaaagaaa
    53281 gaaacaacaa atgccgggac agttgaccac atcatatgct tgatgtgttt gaacaaatcg
    53341 gcatcaacaa tagctgctgc tagatttgtt gattcggata atggagacat cttatctcca
    53401 aaaacggcac ctgaaacaat agctccaaca accagcgctg gatttaagcc tagtgttgtc
    53461 ccaataccga aaaatgcaat cccaatcgtt gacataacag taaaggcact ccctacagcg
    53521 ctacctacga ttgcacacac aacaaataca gaagggacaa accactggac actgatcaat
    53581 ttgaacccaa tgaccattag agttggaatg atccctgctt gtatccatac agcaatcaat
    53641 gaaccgacta aaataaaaat aaagattggg atgattcctg gtttgatgcc attgatgatt
    53701 ccttcgtgca gccaatctgt cgggtatctt tttatcactg catacaacat gaccattccg
    53761 atcgctgcta agatcgtgat attaggtgag acctttaatc cgacaacgcc aatcgcaatg
    53821 cctaaaacaa taaccattaa tacaagtgtt gcttctaaaa aacttggtgt tccttttttt
    53881 cccatgataa tctctccttt tttagttgtt cttatgttct aaaaaagtta agatatcgga
    53941 ttactccgcc gcaattcatc cgcgattcct cctttataaa aataaaaaga cctgttttaa
    54001 actaaggacg aatgactccg cggtaccacc ttaattaaaa acagatctgt ttttcacttt
    54061 caaactttta ttcaaatgta tggactttcc atgtaattcg tcaattaggc ttgatcggtt
    54121 cacagcgacc accgactttc tgaacaaaac acctaaccgc tactgcgtga aaagttgact
    54181 tgtacgaagt ttaccttcca taagatcatt tgtcaatgaa aaagaaaata ttttttcatt
    54241 tttctgaaaa ttatttttat aactttcaca cacaagttta ttttttacta gaaagtagcg
    54301 ccctcttgtt tttttcttgc tactatttct tgatgttctt gcttgattct ttctaatagc
    54361 tttggctctt tcaacagatc aagagctgta ttggcgagta gttctgctgc aatcgcaata
    54421 gaagcaaggc ctttgtcact tttagcagca gctttgaatt cttctgtgtg tccggcaata
    54481 tatgtctcag agattgctac cgtaggctgg attgttggta tgacttggct gacatttcct
    54541 acatcagaag aaccgagact tgttctttgt tccgtttcta tttcttcatc tggaacacct
    54601 gcttcttttg catgctggaa gaataagtca tcaaaagaag gagtaacgat gacatcatca
    54661 actgcatttt ggaacaatcc aaactcaaaa gtcgtgcccg tacttatcgc agcacctcgt
    54721 acgatatttt ccactttttc atatacttta tctaatgttt gccgatttcc tgcacgtaaa
    54781 tagaaacgtc cagcagcgta atctggaatg acgttggcag ctactcctcc gtctgtaatg
    54841 atcccatgga tattgacatc ttttggcaat tgcaagcgta gagcgttgat tccattaaac
    54901 acttggatca atgcttccaa agcatttact cctttttcag gtgctgctgc tgcatgggaa
    54961 gcgacaccgt aaaatttgat gtcgactgga tcattcgcta aagattctgt cgttttccca
    55021 taacgaaaag ctggatggac gcataacgct acatcgacat cctcaaaaaa accttctcga
    55081 acaaagctgc ctttagctga tccgttctcg cccccttctt cccctggggt gccatataca
    55141 cggatttctc caccagtttc atcaatgaat tgcttcacta tgctggcggc taatacggag
    55201 taagtaccaa acaaattatg cccgcatgca tgaccaatac ctggtaaagc atcgaattct
    55261 gccaaaaagg caattgtggg accgggttta ttggaaatat aacgtgcatc aaaggctgtt
    55321 cggtgtccag ctacttcttt ttctacccaa aacctttctt tttctaattg tttaatcaac
    55381 gctgctgagg aataaaactc atagttactt acttcaggat gttcgtggat atctagagca
    55441 agtgcttgat attctggtaa acgatattgg attagatcct tcaattggtt tgttgagatt
    55501 gttgttgtca taaaaaattc ctcctatgct agtcattttt cttattttct cccgaatgtt
    55561 tcccatgcag gcacgcttga tccttttgat gttttctcga ttactttgac tgtgtcttct
    55621 gtttgataag cgtctactat tttttgatac gttttattgt tttcatcttc ttttcttgca
    55681 acgatgatat tcacataagg acgtgcatgg tcatccactg gttctaagaa gatggcatca
    55741 gaagcaggat taaatccagc atctacagct acaccgctat tgatcactga aatgtctaca
    55801 tctgacaaag cacgtgctgt ttgggaagca tctaattcag aaatgtctag attttttcta
    55861 ttctcggtaa tatcagaaac agtgggcgct tgtccttttg ccttatccac tttgatcaat
    55921 ccagcagttt gcaataacag aagagctctg ccgccatttg taacatcatt agggattgct
    55981 acttttgctc cgtctttgat atcagctaca tccttcaaag tgttagaata aattcccagc
    56041 ggtgcattga cagtatttcc gatcgatact aaatcagttc cgtgttcttt attgtaattg
    56101 tctaaaaaga attgatgttg gaaagaattc aaatcaatcg atccatctgc taaagccaca
    56161 tttggttgat tgtaatctgt aaatttcacg tattccaaat taatgttctc ctttttcaaa
    56221 cggtctttca cgttgtccca tacatctgta tcttctccaa taatccctag ttttacgata
    56281 gtttcttttt tgtcagttgt atctgctttt ccttggctac accctgccaa ccaaataatt
    56341 gctacaaatg taatgactac aaaacgaata atttttttca ttttttctcc tccactttca
    56401 atgtgtaatt tttttaatca gttgattact gataaattga cttaaaaaaa ctaagattag
    56461 aatcaataat gtagccacaa tcgttacatc tgtttggaat cgattatacc ctctcgatat
    56521 agcaagattc cctaatccgc ctgcacctac tgctccagcc atggtagtca gtccgatcac
    56581 gttgatgata gtcaacgccg agacccgaat gataccaggc aaaccttcta acaaatacac
    56641 acgtaaaatg ataccgattg gactggttcc catcgcttct gccgcttcga tcaccccagg
    56701 atcaacttct agcagtgcgt tctcgatttg acgagcaaaa aacggaacaa ctccaaaaat
    56761 caatggcact aaagctgctt tcgcaccaat cgtcgttcca actaagaaac gagtagtcaa
    56821 tgctaaaaga gaaagcaaga taatgaaagg gatggaacga atgatattga tcagcttatc
    56881 aagtatttca aatagcagac ggttagctag taatccatta gggcgtgtca ctactaacgt
    56941 cacacctaag atgattccaa tcatcccgcc aatgaatgct gtccaaaaag acatatatag
    57001 tgtttgcttc gtcgcttcga caaattcatc cggaatcaaa taaacattgg gcaaatatgt
    57061 tttaaagaaa tcagtcattt tatcttcctc cttcgatcac tttgatacga ctatctaaat
    57121 cgtttttttg taaaatattt atttttacac cagatttgat caaataatcc aatgcttttt
    57181 tccgctgttt ggtttctcca gctaaagtaa cgatcaaact ccctaacggc gtttcttgta
    57241 ataactctac attgccatat aaaatattcg ctgttacttg atatttgctg tacagatgag
    57301 cgattagagg ttcgttcgtc tgatttccaa tataacttaa ttccaccagc catttattgg
    57361 cgatctgatc ggcaaaagca gaatgggcaa tgatcgtttc taatgcttgg tcaagatgag
    57421 tagctgttcg aataaaatct ttggtcaatt cttcttcagg attgctgaag atctggatgc
    57481 tgctaccttt ttcaacgatt cttccatctt ccataaccgc taccttgttg cagatttctt
    57541 tgacaacttg catctcatga gtgatcagga cgattgttaa acctaactgg cgattcaatt
    57601 tttttaacaa tgcaaggatc tgaagggtcg ttttcggatc aagtgcactg gttgcttcat
    57661 cacataataa taccttaggt tcattcgcca aagctcgtgc gattgctact cgttgttttt
    57721 gtccccccga cagttgttta ggataagcag atgctttttc ttccaaaccg acaagttcca
    57781 gtagttcatt cactttttga cgacgttcct gtttcgattt tccagaatac tttaaagaaa
    57841 aatcaacgtt gtcaaaaata gttcggcttt ccattagatt gaaatgctga aagatcatac
    57901 cgatggcctt tctttctttt cgcaattctt tgggagagag ctgactcaga ttcgtctgat
    57961 tgacaatgac ttctcctgct gttggtttct gcagcaaatt catcacacga actaacgtac
    58021 ttttccctgc acctgagtaa ccgacgattc cataaacatc gcctttttca atcgttaaat
    58081 ctacagaatc tactgcctgt atctcttttt ctttttgttt gaaacataca gaaacatctc
    58141 gcaattcaat cattaaaatt cctccttatc taaaaaaagc gtcctcaaga aaatgaaaat
    58201 gtcattttct tgaggacgct tttttgcgtg ttaccacctc atgttcaagc tgtgttcaca
    58261 cacaactcct cttcaagtac gatcatactc tagcaagata tcggtcgcag ccgtcatcgc
    58321 cttacatcta tgctcgggat gaattgctcg atggccattt tccaatagtc gttccttgct
    58381 tcttctcagc taccgaagct ctctgtcaaa ggttcttcta tcgtacttac catttcaatg
    58441 caaataatat tcaaaaaaaa agtcctttta ctaacataaa ctatgtcagt aaaaggacga
    58501 cgtatcgcgg taccaccttt tttcggaagt ttccttccct caagcccaac atctcaaaaa
    58561 gagagattgg cgttcgtttt aacggtcgaa cagttccgaa tttgcctact tatcgacaaa
    58621 ttattctcca aggccatttt cagcttttct tacttgactc ttctcaccag ccagagcctc
    58681 tctgcaaagt ttccaaactt actttccttt tcaacgaaat cgatattttg ttgttgggat
    58741 taatctacat gaggaaaact gaaaagtcaa gtacgaaatt caaattattt tttctatatt
    58801 tatttttctg tttttttatt taacatttca ataacagttc gaagatcttt tccttccgca
    58861 agaagtttca atttttcctt ttcttcgacg gtataatttc ggacaaaact ggaatcaggt
    58921 atcaaaacaa cgcctaatcc tgctcgtgaa gcagctgttg ctcctactaa agaatcttcc
    58981 actgcaaagg ctgaactagc ttctaatcct gttcgttcca aagctgtcag ataaggaatc
    59041 ggtgaaggct tgttctccga cacttcgtct ccgaatgtaa acgtgtccaa gtaatcagct
    59101 aatttaaagt gatccaagat atctgttgct cttttcgtaa cagtggtcgt agcaatgcct
    59161 agtttcatat gacgttcttt taagtctgcc aatatttctt ttgcatatgg ttttaagtgg
    59221 atggctccgc ttgtcagctg ttgataaaaa tattcttcac gcttcgctcg gacttcctgt
    59281 actttttcag ggctacctgc tgctttcact aaaatatcaa aactttgttt ccagtttttt
    59341 ccgccccaag cgtcaacgat ttcttttggg atatggatat caaattgctg aaatccccaa
    59401 agccagccat cacgatacgt tttttctgtg tcaactaaca aaccatctaa atcaaatatt
    59461 gcacctttca tctatacatt aatcctttcc aaaacaatac acatagttta gcacgactgg
    59521 tccaaaaaga acagaagcaa agaaccagcc ttctcgttta taagagttct tggaatcgac
    59581 ggatatagat tttcttcaca gctgtcacaa gcgccagata agcgatgact gtagcaaata
    59641 accataacca gtaattgcca ggaagtggca tcaagcctaa ttcagcacca aaacttgtaa
    59701 aaggaaggac agaaccgaca ataattccta atgtagtgat aacaaacatg gcaaatgttg
    59761 cgttgctttg gataaatggt actttcggtg tacgcagtgc atggagcact aaggtttgtg
    59821 tccatagtga ttcgacaaac catcctgcat ggaataatgc gatgaaaatc actcgctgtg
    59881 aactatccaa tgtatggaaa cttccgccca ctacagcagg acaaataaca aaatacatca
    59941 acaagtaagt agtaatatca aatatcgaac ttgttggacc aaagtaaacc atgaattccc
    60001 caatactaga tgcattccat ttttttggct cgtccaaata ttctttatcc atccgatccc
    60061 atggcaagga aatgcaggaa acatcataga tcagattcaa aaacaaaagt tgtaaaggca
    60121 gcattggtaa aaatggcagg aacgtacttg caatcagcac ggaaaacata ttgccaaaat
    60181 tagaacttgc tgtagccttg atatatttca tgatattccc aaaagtttct cgtccagaaa
    60241 gaaggcctct ttccaaaatc gtcaaatctt tttctaaaag gatcacgtct gcagattctt
    60301 tcgcaatatc cacagctgta tctacagaaa taccgatatc agccactttc attgcaggag
    60361 cgtcattgat accatctcct aaaaatccga cagtatgacc atttttacgt aaagctgtcg
    60421 tcaaacgtgc tttttgctga ggattcaatt ttacgaatac ttcatggtct tcagctactt
    60481 gtgctaattc atgatcactc atttccgaga ttttctcacc ggtaaccaat tcattgatct
    60541 ctagacctac ttgacggcac actgaacgtg taactaattc gttgtcccca gtcagaactt
    60601 ttacagctac accatgttct ttcagagctt tcaacgcttg tttcgttgtt tcttttggtg
    60661 gatcaaggaa agcaagataa ccaatcaaaa ccatgtctga ctcatctttg actgaaaatt
    60721 ctccaacgac gcttggattg gtcttttgtg cgacaccaat cactcgtaag ccatcttcat
    60781 taagtgactg tacttttgca agtacggctt cttttcgttc ttttgttaat ggtgtaacag
    60841 taccgccaag atcaataaat ttagaaatgt tcagcatttc ttcaatcgcg ccttttgtga
    60901 tcatttgtgt tttaccagct ggatcagcaa ccacaacact catacgacga cgttcaaaat
    60961 caaaaggaat ttcatccact ttttgataat tgatcttatc tgtatctaaa gtttctgttg
    61021 cttcatcaat gatagccaca tctaacaaat ttttcagccc tgtttgatag tagctattta
    61081 gatacgcatg gcgcaaaaca cgatcatctt catttccttc acaatccata tgatattcaa
    61141 gaatgatttt atcttgtgtc aatgtccccg ttttatccgt acataacaca tcgattgcac
    61201 caaagttctg gatggcattc aaatttttga tcactgttcc ttttttggcc atcacacttg
    61261 ctcctttgac caaattcgtc gtaacgatca ttggaagcat ttcaggtgtt agaccaactg
    61321 ctacagatag tccaaaaaga aaagcttcta gccaatcccc ttttgtaagc ccattgatga
    61381 cgataactgc tggagccatc aatgacataa atttgatcag tagcatggat gttttatgga
    61441 tgcctaattc aaagcttgat tgaattggtt tttcagatag cgtttctgct acatgaccaa
    61501 atagtgtttc atttccaaca gaaacaatga ttccttccgc acttccactg atgacattac
    61561 ttcccataaa gacaagattt tcgtaacttg tttcgctttg ctgatcgtct tcacatactt
    61621 tcgcatgctt ttctactgga tagctttccc ctgtcaatgc tgcttgggaa atgaataaat
    61681 cctttgcgga caataaacgc atatccgctg gtatcatatc ccctgctgaa agccgaacaa
    61741 gatctccaca gacgatttct tccataggaa tctctgtgta ctttccatta cgttttacag
    61801 ctgccgttac tttcacaagt gatttcagtt tttcagccgc ttgattggaa cgtacggact
    61861 gaatcaacgt cattgtcccg ctgacgataa ccatagtgaa gataatggct acaccgaaaa
    61921 gatctttatc tccaggagct gctaatacat attccgtgat gaatgaaata attcctaatg
    61981 cgatcaacac taatgtaaat ggcgtgatgt atgctttcaa tatttctaca atgaatggtg
    62041 tttttttgcc atatgaaatc gcattttcac cgtaattttc tcttgaacgt tcgatttgtt
    62101 cttctgtcaa tccatttgct gatgcatgga atagttcaaa taattcttgt ttcgtttttc
    62161 cagcaaaagc tgcatagatt ttttgtgtat ctttcttttt ttccatctca atctctcctt
    62221 tgtgtccaaa agacagctgt tctcgctgct tttggtcttt agctattcat cggatcgata
    62281 gagaaaaaac tgaaaggggc tgagaacaga tagataatag ccctggcctt tcctctagat
    62341 ccttgttttt cgaatgactg tcatccattt gttctcatct cctttactaa gtaattttaa
    62401 ttcatgactt ccaatcattt ttcgaatagt tatttttcca attagaccac ctccttttta
    62461 tttttcaccg atggggattt gcggcaacaa aaaaacctct cgccaaatac tcagcgaaag
    62521 gtttgaaaaa gcatattaaa aaaagcttct cagatctcat cgttgagttt tgacactgta
    62581 caacgtaaaa agcagatacc tgcttttagc taccttatga aaagccttat ctcgacaatt
    62641 cctgttctac ccattggcgt ctctcgacgt ttttgggcag tagcctatgt ttgtatagga
    62701 gcctcaccta acaaatctta ttcggttttc cttcgttaat ataacaacta aaaaagagga
    62761 tgtcaaatca attttccatg tttttcatac tttttttaaa atacacacgt tatattcctg
    62821 tctcacgcgg ttttatttgt ctcattttcc acctcccgct ataatagaaa tatagtagga
    62881 aacgaggtgc tgttatggaa agaacacttg ttattatcaa gccagacggc gtgagacgcc
    62941 atttagtcgg aagcatcatc caacgttttg aagcaaaggg actggccatt gctgaaatga
    63001 agtttgaaac tatgactcct gaattagcaa aagaacatta tcagcacttg actgagcgca
    63061 gtttttttga tgaactgatc gattacatga cttccggtcc tgtcgtttat cttgtgctgg
    63121 tcggcgagga agtgatcgat atcgtccgta agatggttgg agcaacaaaa gctgccgatg
    63181 ctgttccagg tacgatccga ggagactacg cgctgccggg gactgaaaac atcattcacg
    63241 cttctgattc ccgtgatgct gcggtaaaag agatcgcccg ctttttcccg ccattcgata
    63301 taaacaaacc gtctgaaaaa gcggcgaagt gatacaaatt ctaaactgct ggtctagttg
    63361 ctgggttcag caatggccag cagttttttc tctaaggacc tccgttgatt ctttcctaac
    63421 atatattcga gcactgtgaa gaattcttgg tagtctttcg tcttttcttc ccctaaagca
    63481 gcagaaatca atctttgata ataatctgcc atcaatgttt catagatcac tgtacttctt
    63541 tctttatgtg ataagctccg tttcatatct tcattcacac tacgtgcctt tttcaaccga
    63601 ccattttcta tataaaacga agtcaggttc attaaaaaag taaagagata ctgctcatga
    63661 ttgttcaact gtgctaatcg tcgcattctt tttttgattt tcaaataatt gttctcaatg
    63721 aaccgatcac tgaatatcca aggaaaatca gctagaatag atagttcaaa ttgaccatag
    63781 tctggtatct gcatcaagta ttcttcaatg attcggcatt cataacgtaa aaattcaaat
    63841 tctgtctcag atacttctgt tttttcgacc atgtgaagat tcaaaaccaa ataatacaga
    63901 tcttctgttt tcttaaaatg cctacggtta ttgctgatct ctttataagg atcaaagctg
    63961 tcttcttgta cccgatctag cattcgtctt tttttcttta actttattgg ttcatccagc
    64021 tggtttcgca tccattcata ttctgcaagt gtcatgttca ttcgctctaa aaatgatctc
    64081 aatgttacaa atgacatttt tttcactgaa tttgtctcaa tcccgactag agaagtctta
    64141 aaacagattc cttccgctaa ttgggactgt gtcaacttct tgttgactcg aagtttcttg
    64201 atcaattcac catcatacat aatagttctc ctttttaatt taaatttttc cacattcaat
    64261 aaatagatac gttaaaaagg aaaaatacac gaaaaaaata aaaaaatgtt tttttcataa
    64321 aaaataccaa ccttcaagca ttagaatgtt gtctaactac tgaaggttgg tttgattgtt
    64381 tattgattat ttttttgctg ttcaacgtct gttcttgtta ctggatataa gttggttgtt
    64441 gttttattac cattttttga aaagacactt gtcgaatgtt cgcctttttg cttttcgatt
    64501 gcttcattac gttccgcttc atttttatag tcatattttt tcggatcaat cgtctcaaat
    64561 ccgtttggca cataaaaccg caagagattt tcctgattca gcttatctga aagacttaac
    64621 gcagtcttga ctttttcctg atctttggag atttcctcat cgattcctgc tgctttcgta
    64681 tcgatgattt ctcctgtctg attattgtaa gcttttcctc ctaggacggt gtatttgggt
    64741 gtcacaaagt tcccatttcg aaaagcaact acttgatcat gctgagaaga taataagtct
    64801 gtaccaaaat gaagataatc tttatcatcg attcccaata gatgtagtaa tgtcggcaaa
    64861 acatcgattt ctccaccgta ttcatgattg actgtccctt tagtataacc aggcatatgg
    64921 atcatcaatg gcactcgttg catctgtgcg ttgtcaaatt catcccatgt atctggatct
    64981 ttaccaagag cgcttgctaa atctttatta tctgtattcg agatcccaaa atgatccccg
    65041 taaatcacaa agattgaatt ttggtaaata ccagattttt tcaaatacgt aaaaaattgt
    65101 tccaatgatt gatccagata atgtgccgtt cgaacataat tatctactgt gctattgcca
    65161 gtattcaaag atggaaagtc gaaattcttg tcatccgtat aataaggcgt gtggttggtt
    65221 acggaaagaa atttcgtgta aaacggctgt tgtagatgct caagatattg ggcagattct
    65281 ctgaataaat ctttatctaa tatcccataa cctaacgttt cgtcggattc atcaaaataa
    65341 gatcgatcaa agaaattgtc ataacctaag tttttatata catgatctct attccaaaaa
    65401 ctagctacat tcccatggaa aacagcgctt gtatagcctt gcttttgtcc aaggatcgct
    65461 ggtgcggctt gaaagacatt gtctgaccca agttctgtga ataatgagcc ttgaggtaaa
    65521 ccaaatgtgc cagtttccaa catattttca gcatcacttg tctttccctg tcctacttca
    65581 tgaaagaaat tgtcaaagct gatcgttgct tgattctgga aaatactatt taaaaacggt
    65641 gtgacttctt gtccgtctac cttcatatta atcaaaaact gctggaaact ttctaaatgg
    65701 agaacgatca catttttccc tttagcgatc ccaaatgttt cgggatttgg ctctgcataa
    65761 tgtttctttg tataatctaa aacttcatca atcccattac tgcttgcatg cgcgcgaaca
    65821 ctgctagtca ttcctgtttt gattccgtca taaatagtat acgcatcgat tcctagatat
    65881 ttgacaatat atgaacggtc aaatgttcgc tgcagcaatt gtggacggtt ggcttcgctc
    65941 agcgctagat ttcctgaaaa aataagccct gaaagacagg taacagcgat agccatcggt
    66001 ttgccgacag ggttgctttt gataggtatt ttcttgacct tcaaccaaac cagtagccca
    66061 atgaacacag cgatatccag ccagtagatg acatcatggg gcttcatcaa agaaaaggag
    66121 cttcctgaca atccttgcga cactttcgaa aagcctaata cagatttgac tgtaatgaaa
    66181 tctgtgaatt cccgataaaa aataatattc aagtacaaca aaagcgtatt taaaatatca
    66241 atgatcaaaa gaatagctaa cgctggcttt ggctttttaa tatacaaaga aaggccaaaa
    66301 aacaataagg tagtcgcaat tgggttgatc cacaagataa agtactggat cgtaccttcc
    66361 acacctaatg aaaaatctgc atagtaggca atgatcgtct tcagccagaa aaagaaaaca
    66421 gctgtcaaaa cgattgctaa acgattttgg cacaattttt taagttgtgt cacgtatatc
    66481 acttctctct attcacattt tttcttattt tgctcctgaa aaatgaaaat ttcctaaaaa
    66541 agttgttatc ttaagatttt tttattcttt ctaaagatta ttccgtccac ttttcacagc
    66601 ataaaaccgc tgcgatgtaa gcgattaaac taatgaagag ataaaagtct tgtggtgacc
    66661 gcttcactcc acggtattca aaagccagtt tctcggtatt cgtacaaaaa aagaggctgt
    66721 gacaaaattc ttgtcgcagc tccttatttc ttgatgcagg acagcttttt cacaacttct
    66781 tccttaaacg gtgttctcct gccaactcct cggccacaag tcacaatatt tataaaacat
    66841 gagaagctgt tttttgaaat tgttccttgt ggctcagagt taaacggcag gctcaagacc
    66901 tcttgataca cggtgttcaa tcagctgacc ctcggtatta gattatgtca ggacgctaat
    66961 tttacaacct cttggtaaac ggtgttcaaa agcttgcatc tgcggtaata agcccaacca
    67021 aacgaaaaat ataaggagct attttttgaa attgctcctt gtggctcaga gttaaacggc
    67081 aggctcaaga cctcttgata cacggtgttc aatcagctga ccttcggtat tagctcaaaa
    67141 aacggcaaaa tatgaggaac tattttgccg tttgtttctc taatactcag gtcaaaacgc
    67201 tgatttcaca acctctgttt ttcattgtcc ataggattga tattgtcctt gtgatgactc
    67261 attcgtaata attgaggctt gattttcttc acttcccgtt atcgtttgtc cactgccaga
    67321 atctgaagga cttgttcctg tcgactcgtt tttttgagaa gagacagttg ttttcttgac
    67381 ttgttcattt gtctttttcc attccgctaa acgatcggcg accacttttt tgtctacttt
    67441 ttcagaataa gcggtgatca cttttccatt tttcaaacgg gctactttgt cgccatcatg
    67501 agtcaaaagc aaaacggtca aatgcttgtc tttaaattga tattgtctga gagaaatcgc
    67561 actaagtacg tcatcgatat taataaattg attttcttct tttccttttg gcaaataaat
    67621 gtccaattcg cctttttcgt aattggcagt tattttatac tccgcccacc aataagttga
    67681 gaattctttt ttgaaattat ctactgattc tttgcttgct acgatttttt ctgtttcttt
    67741 ctgagcaaga tctgctgtca tttttcctga aaatgctgcg gataaaataa gcagtaagaa
    67801 aaaaccgaat aaccaaaaga gaagaaacgg tctttttttc ctcatgcttt cctccactcc
    67861 tatttaattt tgactattct attatataca aaaaatgaaa tagaaagaca aaaaagttga
    67921 aaaagatcgt aaataattga acttcttttt cacaaaatgg taagaatgga gaatttcacg
    67981 catttgctct caactattct ttcttaagcc tcaaatccgt ttttatctga tacgtctttg
    68041 aaccaatgac ccgatttttt gattgttctt tttccatctt gtgctaagtc tactgaaata
    68101 aagccatatc gattcttata tgcattggtc cacgaccagt tatccataca tgtccacata
    68161 tgatagccta aacaattggc accttcttga atggcttgat ggacatattt cagatgagat
    68221 tggacaaatt cgatccgata atcatcgtgg atcatgccat cttctttgat aaatcgtgct
    68281 tcgttttcta cacccatacc gttttcagaa ataaagcagt cgatatttcc ataatgatct
    68341 cgtacattga tcaaaatatc atagattcct tgttcataga tctcccatcc gcgataagga
    68401 ttcattttac gaccaggcat ttcataattg tcgaaataat cctcaggcat tggaccgttt
    68461 ttagtatcga ttggtgtttc ttttgctttt acccggcgtg gctggtaata attgatacct
    68521 aaaagatcta ctgtattttc tttgataacc gtcaaatcct ctgcatggat cacaggcatg
    68581 agatcaagtt cttttactat ctcaatcaat tcacttggaa actcgccttt tacagctgga
    68641 tcaaggaatg aacgattgaa gaacgcatct gctatttgcg ctgctttaac atcttcaggg
    68701 tttgattcgt ctcttggata gcttggtgtc agattcaaga tgataccaat aacaccacct
    68761 tgctccattt catggtaaga tttgatggct aacgctgaag ccaacgcttc atgatagcca
    68821 acttggatcg cttttttcat atctgactct tctggataat gccatcgata taaataacct
    68881 gcttcgactg gaacgattgg ttcattatga gtaaaccatt tttttacttt cgaaccaaac
    68941 aattcaaaac aacttttggc atatttttca taggcttcaa ccgtttctcg gttcaaccat
    69001 ccgccttttt cttgcagata catcggcata tcgaaatgat acagattcac aaagggttcg
    69061 ataccgtttt caatcaactc atcaaaataa cgatgataga aacgaacggc ttcttcgttg
    69121 attgttccag attcatcagg tatcaaacgg ctccattgga tagatgttcg aaatgaatta
    69181 tgcccagtct gtttcatcaa ctgtacatcc tcttgatact tcgtataaac ttgcgaggtt
    69241 ttttcaggtc ctacttgatc aaagaacttt tgcggttctt ttttgtacca ataatcaaaa
    69301 atgttctctc cttttccatc gcctgaaatc cttccttctg tttgtgggcc acttgctgca
    69361 gaaccccacc aaaaatttgc tggaaattga tattttttca tcaaagcacc tctttttctt
    69421 ttttagttcg ttttagttga ttccatgtat gatattttcc atcacaatca ctttttcatt
    69481 ttcttcctct tcttttttga ttcgttttaa cagctgttct gctgctcgtt ccccgatttt
    69541 atctgttggt ggcgtgatcg tgattttcgg aaggatactc agatcgtttt tatctaaata
    69601 atcatagtga ctgaacgcaa tatccttccc gattctgaca ccttcttgat tgaaacattc
    69661 gatggcacca atcgacatat tgtaattgct gacaaaaata gcagttgccc ctttttctaa
    69721 taatgctttt gccccgtaat agccgctttt tctagaatag tctcctgtaa agacctctaa
    69781 ttggatcgat ggatcatttt ggaccgcttc tttggctcct gctaaacgtt ctcttgctac
    69841 gtagtctgtt tgagtggcag caataaatcc gattttttta tgtccttgtt caccatgatg
    69901 agcgatcact tttgctacac tttctcgatc attcactaat attgtatcaa tacctgctgg
    69961 tccttctgga caattcaatg cgataactgg aatactcatt tttgtgagca tttcaaatcc
    70021 agaccactct tcttcggata agaagacaat cagcccatcg atcacatgct tcatcaggta
    70081 ttcaattttt tgttcaattt tttctggctg atcggcaaac ccgcttaata ataagctata
    70141 cccattttct tcagctactc tttcgatccc tgagacaact tccgacccaa aacggctgga
    70201 aatcccgttt atcaaaagtc caatagagaa gcttcgatta ttcttcaacc ctttagcaat
    70261 gatgttttct ttatagtcca acgctgaaat cgcttctgct atttttttca tgttcttttc
    70321 cttcagttgc tgaccattca agtaacggga aactgttccc actgaaacac cagccatctt
    70381 agccacatca cggatcgatg ccatacattc tcactcctgc cagttacatt tgatttctct
    70441 ttcttgttgt tcgattatga tgaccgcatt ctttgcatag tgttgcttgt catcaatatc
    70501 catataacta aagtcttcag tagagcaact tcctctcact attaattata cttaaacaag
    70561 tatttgaacc ggttcatttt taatatagca tttttttaaa agattgcaac acttttttaa
    70621 aacgctttct gaaagtggcg gattttttgc ctttttaaaa ttttattcta aaatttactc
    70681 tatttgtggg tgttttgtgc gtttttctct tccatccgtt tgaagtttta cattccaatg
    70741 gtataatttc tttatcctat caaatggggg aagtattttg aagaaattaa tcgtactatt
    70801 tattttgtct gcgggacttt tgacattgac tggctgtgat ttgtttggcg gctctgacca
    70861 atcctcggac gaaacaaccg attcttctgt cttaaaagcg gaaaaagcag ataccaccaa
    70921 cagtgtatat acgctaaaag tacgtaaaga tatggattta tccgcgggac agttgacatt
    70981 tacagataaa aaaatggaat ggacacgcac gtatcagaca caaggaactg attcttctga
    71041 atcatctgaa gaaaaaacag tgctgacaga tatcaagatc actaccaaag atgacgaata
    71101 tattatttca ggaaaagaaa ataaaaaaga aacaacagtc atatttacaa aaatcggtaa
    71161 ttaccgtttg aaggatgagg atggcaacat ctacagtcta tagtgccgtc tgttggatct
    71221 tcttttgttt ctccccttct tttctgctat agtaaagaag caagatgatt gtaaaggaga
    71281 cgaaatggat gatcgatagt cctgattatt gtacatgtaa taacaacaaa aatatccata
    71341 cagaatttaa tgaccaagga agcttgagca tatgcgacaa ctgtcacaaa ctagtcaaag
    71401 attcatttaa aacatttgaa tcttatcctg ttcaaaatta tgtaaaaagt agaagaagat
    71461 aaacaaatcc aagcaaaact cactatggct gatttttatg aacttcaaac tcagcttctt
    71521 cctttgatca agcttcatca gtaaaacaaa cagtggatca tttcagttta caaatcaaag
    71581 agtaaagatt tatttatttc aaatatttga atataaaata accaaacgat agaaaggctt
    71641 attctacatc acgtagtaat ttttctttcc cgtcgtttgg ttttttattt ttagcctaat
    71701 tcttgacctt ttgcatgctg gttatccgta aaatattttc cagcaggctt tccttccaat
    71761 tcagctaatt tttcttggat ctgacggatc accttttttg catcttctgg attttctaca
    71821 aaatcgaatt tatccccatc cacttgtatt ttaggacata catcaaaatc ttcataccat
    71881 tgattatagc gggtgttcaa cgtttcataa taggtatata acgtctcatc gctttctagc
    71941 tgttcatagt cacgcccacg ttttttgata cgttctagca tcgtgtccaa agaaactttg
    72001 atatggacca tcaaatcagg ccgttttttt ggagcaacat catctaactc gtttagcatc
    72061 gtatctaata agctatcgta ctgctgtact tcgatatccg ttacccgacc taaatcagcg
    72121 tttagatgga acaacaggct atcttcatag atggatcggt ctagcacatt gtcatcgttc
    72181 actaaagcat ttttcattgc taaaaatcgc ttgttcaaaa agaagatttg caataaaaaa
    72241 gcgtactgct caggatttga ataaaagagc ggcaatactt cgttatcttc gacattttca
    72301 taaaatggtt tagaatcaat ctcttttgca agcatatccg tcaaactgct cttacctgca
    72361 ccaatcgttc ctgaaatcaa aatcactgac atacaaccct tcctcttcta taagtactcg
    72421 cctacgtaag tttcaacagg caatgtttca aaatcatatt cacgtacagc ttggtctgat
    72481 tttaaatacg tatggagact ttgtgtaatc atcaagttcg taggtaccgt ctcttcttgt
    72541 acaatgatca tcggtttttt caacatagtt gccacaccta attcgtaagc cgttcctgga
    72601 tcgattgttt gatgctcaaa gtcaaggata gcaacaacaa attctgcatt tgtcagttct
    72661 tccatatctt tttcgtatac ttcctgcgcc catccagcgc tgaatagttc ataattgctt
    72721 tcttggtgat gacgtggaga gtagaaactt gtgactgttt tgttttcctc caacgctttt
    72781 tcgatacgac ttactcgatc gatttgctcc tctgaaaaaa atggtcctgc taaatatatt
    72841 tgactcatta ttttgcctcc ttcaataata actgattttt aatagatact gctcgtaatt
    72901 cattgaccag ttccaatgga ttgttggaaa agattacttg atccaaccat tttttatcca
    72961 taaaatcctc ttttgcaaaa gtttctaata attgttgcaa gccgctgtaa taaccgccaa
    73021 tattcaatat tccgattggc ttgtcgggcg tcagaccgat tgctatccaa gaaagaagtt
    73081 gtgagaattc ctccaatgta cctagacctc cagggaaaac gaggacagca tctccctttt
    73141 caaataataa tacctttctt tcatcgatcg tttctgtagg aataaatgta gtaacatctt
    73201 ttccaggcaa ttcagtttca aaaagcccat tcggatagat acctgtgact tttccgttat
    73261 tttccagtac tgttttacta atcactccca taatcccgga gtatgaacca ccgtaaacca
    73321 gttcgatttc ttcttgtgcc atgtattttc ctaacgtttg cgcaataaat ttgtaacttt
    73381 ctttattacc aaaacgggaa ccgcaaaaaa cagtaagttt cataaaaaaa cactccctaa
    73441 ctcaaaagtc tatcttcatt ctacacgtgt ttttttaaaa taaaagacta gattttgtag
    73501 ttttttagtg gtatatagga tagacgccac tatatatagt atttagaaaa aaatcatttt
    73561 tcagccattt tatagataaa acaaaaataa ataacgtgtt ttcatcgata tgaaatgact
    73621 tacttataga agatactggg atttcgtcct atatgccaat aacgtgtatt attttaaaca
    73681 acaaatactt gtttctttta ttaacgaaaa aatcattttg ttctcgtgtt atgtttcact
    73741 gataaatgat gtttctctaa ataaaaaagc cgacgaacta aacgatcaaa atttgatcat
    73801 ttttgttcat cagcttctcc taaaaatctt tttgttaacg ataaatagct ggatttgtaa
    73861 aaatatcact tgaatcgtca ctgctggaag aaaattcagt gataaccgca cctgttgcgc
    73921 ctgcctggaa ctagtgtttg atattgggct cgaacgtgta ctgatctcta gcatgaagaa
    73981 taatttcttt ttttactgta taataacttt ctttcctttt tggaatagta caggaaagtt
    74041 tttttgtttc ctttccttcg acataaggta taccagaccc tttcgacaac gaaaggttct
    74101 catttttcct tcatcgtcat ttcaaggagg gtgccgatgc tctggacagt ttcgatcgct
    74161 cctaaaccaa aatctgtata ttcgattctt tctaactctg attctttcat accattcctg
    74221 tctcaaggta catctattgt acttttttct tgtaatccat tctgcctctc ctaactaatt
    74281 gtcaaatcat cccaagatat gtcttcttcc tctttttctt cttggatgat ttctgcattc
    74341 ggatctactg gttttttcaa taataaaatg gttattcctg tgacaaaaga accagctaac
    74401 aatgcaccaa tgaatgccca tggtctggtc atcgtagcga ctgcaaacat tcccgatgcc
    74461 ggaatacggc tatctgcgcc ccaaaacatg cttaatccgc cacctactgt cccaccgact
    74521 cccgttgcta tgacattgcg tgccaagtcg ttcaatacga tagggaaaca tccctctgtg
    74581 atctgacaga tccccatagg aaaagcggtc ttcaatgtat cgatttcttg acgattgagt
    74641 atatttttac gaatgatttt ccctaagaaa taagcgatcg tcaagccgaa tggggttacc
    74701 atcgaagcta aaatcaatac agtgattggt tcatagattc cttctgaaaa tcgtgccaca
    74761 cccccttatc cagaataaat ggtaatccag aaacagccgt gtatctgcgg taataagcct
    74821 aaccaaacga aaaatatgag aagctatttt tgtttggctg ttcttattac ttgatgcagg
    74881 gcagcttttt cacaacctct ttttttattt atgtttcata atcaatatgg taaggatgca
    74941 gctccgtatg gtagaccgcc tccgaatatt caatcatttc cccaatttgc gtagacgatt
    75001 tccgtatccg tttgatgccg atctgtgcgt ctgttttcag aattccttgt tcttcttctg
    75061 ttaaaaatac tgccgagaaa tcatcagaaa atgagtcaat agtatatcct tttttcgtca
    75121 gcaaacgata caaagattct ttgccaaatt cttctctgct gaattgcatc atttcttgtg
    75181 gaagataatg aacaaaataa atataaggct gattgttcaa ataatataag cgcttaaaac
    75241 aaacagcttg ctcaccgaaa aaggaaaaca aaggatcttc cttctttata tggaccaatt
    75301 gcaaatccag cgtttctttc cggacttcat atcgggagtt ctccaagatt tgcgtaaagc
    75361 ttgccgcttt ggataatcga ttgtaaggac gattgcttag aaccgtcgtc ccacgaccac
    75421 ttttctttgc gacatattca tctgatgcca gcagttcgat tgcctttcgg acagtgattt
    75481 tgctgacttg aaacagttct tctaattcac tttctgtcgg caacatcgaa ccgactggat
    75541 attttcctga gaaaatatct tctttaattt tatctgcgac ttccaagtat agtacacgtg
    75601 tccttttcat aacgtcaccc tttgctttac tattactaaa agaatagcac ataaaaaata
    75661 aaaaaagaac acaaatcaca tgtgagaagt gtgttctttt tcattcagct gctttaatta
    75721 caagtttacg ccatttgagg caattacttc tttataccaa tcaaaagatt ttttctttga
    75781 tcgattcagt gtcccatttc cttcatcgtc tagatccaca tagataaagc cgtaacgttt
    75841 actcatttct cctgttgatg cactgacaag atcgatacat ccccaaggcg tatagcccat
    75901 caaatctaca ccgtctgcta ctgcattagc catcgcttcg atatgacgac gtaaataatc
    75961 gatccgataa tcatcaataa tcgtgccatc ctcttccata tgatcaatgg ctccaagacc
    76021 gttttcaaca atgaataatg gtttctggta acgattgtat aattcattca atgcgattct
    76081 cagcccttct ggatcgatct gccagcccca ttcacttgcc tcaagaaacg gattttttac
    76141 tcctcccagc aagttccctt ctgaagttgc tgcttgtgga tcagtctcat tgattgccgt
    76201 agacatataa taactaaatc cgatgtagtc cactggatat tcttttagca actggaagtc
    76261 tttttccgtt tgctctaatt tttccggatc gactccatat tttttatggg tacgcgctgt
    76321 gtatgcaggg tattctccac gtacttggac atccgtgcag aaaaaattga attcttggtt
    76381 ttggatcatt gttgctgcct gattgactgg attggcatcg atgctgtaag ttgttgcata
    76441 gataatcatg cagccgattt ggatatccga acgcaattcg tggccgattt ttacggcttt
    76501 gctacttgca acgaattgat tatgccatgc ttggaaaata ttttggtact ctcctgctcc
    76561 attgcttttt actaatcctt gacttaaagc tggaaagtga aaggccgaat tgatttcatt
    76621 gaaagtcatc caatatttga ctttactgct gtatctctct aatactgtct gagcaaatcg
    76681 ttcatagaag tcgatcagtt ttcgattttt ccagccaccg tattcttttg ccaaatgaag
    76741 aggcatttcg taatgagaaa tcgtgatcac aggttcaata tcatatttta agcactcatc
    76801 aatcagctga tcataaaatt ctaatcccgc ttcgttagga gtaccttcgt ctccatttgg
    76861 aaaaattcgt gtccaggcaa tcgaaaaacg ataacatttg aatcccattt ccgcaaacaa
    76921 ggcaagatct tctttgaaac gatcgtaatg atcgattcct cgatgattcg ggtaaatata
    76981 tttttcttga tcaatcgtcc agtcaaattc ttcactgccg ataatcgcaa agcgctgctt
    77041 acctccaggc atagcatctg caacggatag tccttttccg tctcgatcat aagccccttc
    77101 taattgattt ggcagcagtt gctccacccc ataaaaattt ttctgaaaaa cgtgattgca
    77161 tcctgatttc ctccttattt tacaattgcc agaacatctt cgtttgcaat aatctctttt
    77221 tggtctaatt caagtatatc ggcaaatgca tcagtattcg taatgacaac tggagtgatt
    77281 acgctatagc cagctgctct aattgcttcg atgtcaaaac gaatcaataa atctcctgct
    77341 ttgacgagat ccccttgttt gactaagatc tcaaagccat tcccatttaa ttctactgta
    77401 tccatcccga tatgaatcaa aatctccgct ccgtcagtcg ttgtgatccc tacagcatgt
    77461 ccagttggaa aaatagtcgt gatctctccg tctgcaggtg caactagttc tcctacttct
    77521 ggatcaatag cgataccttt tcccatcacg ccagaagaaa aaacttggtc tggtacttca
    77581 ctcaatggca gtactttacc cgttaaagga ctttttaagg tatgccgtgc tgaagtaatc
    77641 ggttctcctg cattcgcatg tttgttttct aattgattgt cttgtgtttg ttcgtcaaat
    77701 cctaaaatca atgtacctac gaatgcaaga acaaaagcaa ttcctgtagc tattactgct
    77761 actgtcacat ttgactctac accatccacc gtattaatga aagtcggaat cgtcaataag
    77821 ctgaccaaac tgctggagaa agcttttact ccggaaaatc cgataatagc tccaccaata
    77881 cctccagaaa tacaagcggc aatgaatggt ttcttcaaag gtaatgtcac accatacaca
    77941 gttggttcag tgattccaaa taacgaagtc actgtagaag aaatccctaa tgctcgaagt
    78001 ttcgtatctt ttgttcgcaa tgctacagct aaagcagccc caccttgtgc caagatggct
    78061 ggaagaagca ttggcatcaa tacatcaaac ccatattgtt cgatattcaa aaacatgatc
    78121 ggtacgaatc cccaatgcat gccgaacatc acgaatactt gccataaact tcccatgatt
    78181 agacctgcta cgattggact aaatccataa atcgagttga agagaccgcc taaagcatta
    78241 ccggcaaccg tcccgattgg tcctaaagca agaaatgtta atggaaccat cactactaaa
    78301 acgacaagcg gaactaaaat catttgcaga aattgcggaa tcactttttt tacgaatggc
    78361 tctaatttac tttgaaccca tacggctaga atgattggta tgacagaaga agtataacca
    78421 gatggtgaaa gaatcactgg gatcccaaag aaactgatag cttctcccgc accagcaact
    78481 gctgtgatag ctggatacac aagtgccata gcaattgcta ctgctaaaaa ctggttggct
    78541 ttgaactttt tagctgctgt aaaagcaagc atgacaggta agaaggtaaa gacaccatct
    78601 gctgcagcaa acaatatttg ataagtaccg ctatcagctg tcagccagcc catcaccgtt
    78661 gccaatgata agaatccttt caataccccg gcggctgcca tcgcccctag aaaaggtgta
    78721 aatatactag agataatatc gatcagacga ttcaaaatat ttttggactc ttcttttcca
    78781 tcctccgaaa ctgcaagacc ttcctcatcc acgatcgatt gataaacatc tgctacatta
    78841 ctgccaatca ctacttgata ctgaccgcca ctttgtacga cttggatcac gtccgggtct
    78901 tcttttaact tttgcgtatc tgctaaagat tcatctttta atctgaatcg caaccgcgta
    78961 gcacaatgta ctaaactttt gacattcttt tgtcctccta ccgcttccca tacacgacga
    79021 ccaactgctt gattatccat tgttttttcc ttctttcttt tttatttaaa aaataaaaac
    79081 ccagattgaa aaaaacagtc acaaacattc gtgaacctat tttttcaatc caggttttgc
    79141 ctgccataca gtaacaatcc ttatgattgg atgctttttt tctcacttac tactctttga
    79201 atatgaatcg ttaaataaat ctgctctgcg atccccattt cctgtttttg cgtttgtcga
    79261 agatactcat tgatccgttc gacacaatga aacgcttttg gatactttcc ttgaactaat
    79321 gcgtagagaa attcatcttg ctcgtcagat ccttcccctt tgagataacg ctgggcaaaa
    79381 aactgcagat gagtaatgat acgctgataa ttcaaagatt cttcatcgaa cacgatgccg
    79441 aagaatttac tgatgatact cagtatatct cttaccattg tggtagcggt catcgtcact
    79501 tgcatgtctt cgtttccttg ttggctattc acaaaatgaa aggcaataaa accggcttca
    79561 tcctcagaaa gttccacacc cgtcttttgt ttcacgaaca aaagagcctc tttcgctgct
    79621 tgatattctt tcggataaaa tttttttgtt tcaaataata atggattagg cagttggata
    79681 ttttcttttg ctcgtgtgat cgcataatga agatgatcgg tcaatgtcag ataaatatta
    79741 ggcgaaaatt caacttttag tttatcttca gccagttcga ctacttgttt gacccattcg
    79801 atctcctctg ccggaatatc agccatcagc tgctggaatt ggtttttagc aaaagaatct
    79861 cttaaacaaa ttctttttgg accgcttctg gcgaaatctc gtccccaatc tttttttgaa
    79921 aagctagtcc ttttcccata caaacgactt cttccccgaa tccatttttc gaaatgacga
    79981 cattgttatt caaaatttta tcaattttca ttttgcttcg ccctctcaag aaaaataaaa
    80041 aaacctagaa ttcgcctact gtttcttagc tgaattctgg ttttgcctgc cgtacagtaa
    80101 caatccattt cttattcaaa atcatcatac catcgaattt ttatttatgc aagccttttc
    80161 atataaaaaa taaaaaaact ggaacacaag tctatctaga aaacaaccaa atcagagatg
    80221 cacctctttg cgtttctctt tttttcagca aattggtttt tccttatcga ttcatatcct
    80281 ttggctgttt ttaatctgta acgacttatg tcccagtatc ctaaaatgtt tttgtctcta
    80341 gattgaaagc agatctcata tcatctgtcg catcttttat cgatgtaaca ctttccagtt
    80401 ctccttgtac aactagtcgc gtgacggcgt ccatgtcgcc acaagtaatt agtgtgacaa
    80461 tttcttttcc ctcgacttca ttcagtaatt gggtatctgt aggagcaact ttttctttaa
    80521 aaaatgtttt gtatgtatac acattttcta aatctgtcaa atagatcttg gcacccatct
    80581 ctaaattttc tagcggtgta aacagcaatt cagggttcgt tgcacgatgg cttgctaagg
    80641 cataatttcc ttttcccatt tcttgatctg gagataatgt tcctgctccg taaagtagtg
    80701 acgtattatc caagcctttg aaaaccggta aattgattga aactgaaggg actgcgatac
    80761 tagcaatcac tggtagatct gttcctctca tttgcgacct catgacccct tctgtcgtca
    80821 ttggttctac cgcatcaaag tcaaaactga catctttatc gttattcttt ttcagatctt
    80881 cttttgttac attcgctata gcatatttat ctcctgtctc tctgacaaaa taatccttga
    80941 tctgttcatt gaaaatcaaa gctagtccta ctaataacaa gaggaacaag aggatattga
    81001 ctagccatct ttttgctttt cctttttttt tcattttctc tccctccaga ctcattttac
    81061 tgtttttctt ttgctctttc caacagccga atgacacatt tctacaactc tgtgtatttt
    81121 tttcgtacac ctgcgctttt ttctacagga tatttcaaat tatttttgat caatttttct
    81181 tcaatgatct catctagatc caggtgaagg ttgtctgcca tcatgtatga atagatcaat
    81241 acatctgcca gttcttcttt gattcgttct aattgtgttt cttttacttc ttccggcgtt
    81301 ttccattgaa aaagttctaa caattcagat gcttccaaag aaatagagat agccaaatct
    81361 ttttcgttat gaaattgtcg ccaattacgt tcatctctaa actggttgac tttttccata
    81421 ctattcattt gcttgccttc ttccaatcac ttcttacttg attaatcata ccattttttt
    81481 acataaaaaa tagatgatgc ttttaaaaaa actcctgttt tcttttattt aaaataaatg
    81541 tcatagaaaa tcaataattt aggtagccac catgtgtatg cagtagcgtg tcttcttccc
    81601 ttgaggcttt ttgtttttcg atacgttctt cttcccaaac agacaacgct actagaatct
    81661 ctcttaatga ttttccttct tcggtgagcg agtactctac tttaggcggg acttggttat
    81721 aggcttttcg atggatactt tcatcttgtt ctaactctct taactgctgg gtcagcattt
    81781 tttttgtgat cgtagggatt tgcttgcttc tccacgccta aaataagcga tattgctctt
    81841 ccctttatct ggtgtaagca aagcagttag cattttgacg atcgtgggtt ccgcttttca
    81901 cttcttatct acttagtatc atgaagtata ctttcgtact aatactaagt agcggaagtg
    81961 tcaactactt tgtttaacta catagcaaaa gaaacagaag ggtgacaacg gtcatcacgc
    82021 ttctgtttct tttgaatatg ctgtgttgtt gtctctatct ccgtgtagac tttcctcaaa
    82081 cttatccttt gacagtaagt cagtaggctg atttgctctt tctagatgcc agatacattt
    82141 ctacaaaaaa atagtgattc tgttttgaaa attcgatttt tagttctgca ttttcgtaaa
    82201 catccaacat ttttttcgca ctgtatagac ctaacccgcc atttttttta gaggtttttc
    82261 ctcttttgac catctccgat agcgtcaaat tcgttggatt tgccttgttc gctatactaa
    82321 aacgtgatcc ctctttttct tccagcagat tgatcgtaat cggactctga tcggctacac
    82381 gatgatcgaa tgcgttagaa ataaaaatag ataaacagcg aataaaaaca accagatcaa
    82441 tcgggattgt tttcacttcg acaggaataa ctacttggat cgggattttc tccgattctg
    82501 ctttttctag aaattttaaa aagacacccc tgacagctgg ggatacaata tttgttagct
    82561 gttgtatttg cggtttttca aaaatagctg cagaatgatc ttctaatatt tctaaaaatt
    82621 ccaacgtttc ttttttattt tcctgaagag taatttttaa tgaaaacagt agacttttat
    82681 aatcatgttt gaattcctct agatgatggt aatattcttc atttatttga tacagttgaa
    82741 gcgattcctg atgttgtctt tcttttactt ggaaactgat caacataatg gaaaaaaaca
    82801 aagaaaaaaa actgatgact atcgacaaaa gagatagaag cagataatta gatgagcgga
    82861 agtgaacact tcccaatacc aagtaaatca cgccccagct taataaaata caaatacctc
    82921 caaaatagtg ttcagttgga taagtaaaaa gcaagttgag aaatctcgtc tgtttgtcta
    82981 tactttttac taatagatag aaaataaatg cgataagtag tgcaaaaaaa cttgctgttc
    83041 caagatgtct ctttcctaaa taatccatca gatcaaaaac cagaaaaaag ctgagtccag
    83101 tgatagcaaa aaaaagatta ctgatcaaac agctgataaa caggtttttc gtagtaaaat
    83161 aaaaaagaaa catcaataat aagccaacta ggtaaggaaa gctcacttta gggataggaa
    83221 gtaaaagtgt caccaccatc aaagctatac aaccaaagct gttttttact agcagttgtt
    83281 tcgaaaagaa taaatagata cctaaatcta aaatcaaagt aaaggtcaaa taaagtgtca
    83341 ctgttgcgac catcttattc ctccattgtt ttgtttcaaa atgtacacat atttttttaa
    83401 taggagcctg catatgaaaa agtattttat catagaagat aaccagtttc acagcgaatg
    83461 gatcatcaga gaattggtca atcatcatat cgagaatatc gtgcagctca cttctatctc
    83521 tcaaatcaat cagttgatcc agttgggcac tattgataat cacgatgttt tctttatcga
    83581 tatcgacttg aagcaatcac tcacaggtat tgatgtcgcc gaacaaatac gtaaaaaaaa
    83641 tgcacatagt aatattgttt ttttcaccgc ttatacgaat tttgcagtag agatcatcaa
    83701 tcggaaaatc cttccgattg gatatatcag aaaagacagg aatttatctg aacaaattcg
    83761 tcaagtgcta gaacagatca attggaaaga acagcagatc gtaaatgtcg ataaaatctt
    83821 tattgatcaa aaaggtggaa gtctcgtcct gtatcctcgg gaaattttat atattgaaag
    83881 tatcaaaggt ttgaaaaacc aagttatggt caaaacaact acagaagata aattagtgaa
    83941 tacttcttta aaacaattga agacagagtt agaaaagtat gcttactttt tacttttaaa
    84001 atcttactgt atcaacttat cgcaattgca gaaaattgat tctgctcatt atgtgttaga
    84061 atttttcaac ggtgactcct tactcgttgg tcgaaagatc tttgaaaaga caaaggaacg
    84121 tttccatgac ttccaaaaaa ctgcttcgag ttgatgaata agagctgaga cgtaagcata
    84181 gcagatttca gggagtgggc cttgaatcgg ctccactccc tgaaatcgtt gatatgattt
    84241 tacgcttcct cttctgtagg agcatctgtt aacgaccatg tgaatgttga aacgtagttg
    84301 tctacagcat aattggatac aggaacaaat aattccactg attgtctccc ttgttccaca
    84361 ttctctccta atgaataaat ccatgtgcca atcccttcat ttgctcctgc agttactaga
    84421 tctactgcct gatctgctgg gatttcgatt ccttcagcgc cagttccaga aacggtagat
    84481 ggcattccac tgctattagt tgcgctattt cgaatcacgg cgtttttgaa tttcaccttt
    84541 gaaccagtta gtttattcgt atcagatgtt gtaccaataa attctgttcg tttgactgat
    84601 aatttccaac cggcataatt tccgctttta tccgttactt gtacgaaatt ctgtacttgt
    84661 gtttgtgctc cagtactgtc cgttccgctt tgtaatgcag catatactgt ttttgctgta
    84721 cctaacttga ttgttccaaa atcaagatct ggagcttggt caatcgtcag taatccggat
    84781 gttccctgat ttggttcgtc aggtgtaaaa ggagtatcag gatcatttgg atcaacagga
    84841 ggaactggaa caacgtcttc aggatttgca gcatctggtt tggtcacaga aatcgttcct
    84901 tctgtagtgg ctgagctctt attctcagca aaaacacttt gtgtacataa taatagactt
    84961 ccagctagaa cggtacttaa tgcaattgtt tttttcattt ctttttcctt ctttctttta
    85021 aaataaataa tccagcaaat aagccaataa gaatgactcc aacaagtatc agccatcgcc
    85081 agtcaaatgt ttctggctga ttttttaaat caatatcctt ttcattcaat tggtccgctg
    85141 catcatcagt tatttcaaaa tcggtatgga gattccagcg tttttctttc caagcaccct
    85201 tcacaaccgc ttgataatgt cccggagcta attttttcct tctaatggga caagtaaatc
    85261 aaaatttgta ttgggtgcta catctatttt ttcttttttt attgaaaggt aaggctcttt
    85321 tgtttctttt ttgtagattt caaccgatgt agtcaagccg aacatataag aagcatttgg
    85381 attttgaaga ttcgccttaa tcacatttct tccatcgctt tgatccgcat aagctttttt
    85441 taatttcaaa tctggggaag actctttttc gctatttcaa atcaagattg ctttcacttg
    85501 agaaaactga ttgacgacac caactgtact tttgttagaa acgttctctt ttttttcttg
    85561 aaacgtgatc cctcctgcga ccacaccagc cagctctttt tctggcgctt tcagtgaaag
    85621 tgtctcagtg accgcacttt gaggaggaac agttatttct cccactgttt ttgctaagtt
    85681 tttcatatca taacttaatg tttcatcaaa tttacttttt gattctccat attcgatcac
    85741 accgtttgaa ttcgtcgtag cggagtggat caatgtctca actgttactg atttatctgt
    85801 tcggttaaag accgtgtagg ggatttcctg tgttttccca ggctccatcc ttacatttat
    85861 atatgttttg ttcttatcaa tctgattagc cggtaattca aaatctaccg caaaattgaa
    85921 ttcggaggca tggacaggtg tctgccaaag gatgaatcca aggagaagga tcataagtaa
    85981 agagcagttg tttcgatgac ttttattcca tattcgattc atcaatcatc ctccttgatc
    86041 tttattctgt cggcgcatct gctaatgtcc atgttatctc tgctgagtaa ttaccagcta
    86101 tctgattttc tttggttaag acaagtttaa acgcccgacc gttatttaaa tattctgaat
    86161 aatctgcttg cacattcgtt gaattttgtc ctctgacaat ttccagttct tcttcattca
    86221 ctaattgata ctcctctcct ttcttgaaat ataggacatc ctgcatagaa aatcctgcat
    86281 catttgtgaa aggctgagat aattttatcg ttaagatcca cggatttttc gtttctcgct
    86341 gatcataaat ccataatttt tcctgtatat ccatttggcc aaatgcttct tgtgtcaaac
    86401 cagttgcttt gatctgacca aaatcgagtt tggaaggggc aagaaatgag agaccacctt
    86461 ctactacgat cttcgtagca ggtgcaaaag gcggggcatc atgataaaca actggcgtat
    86521 cacttggatt gtgattccca atttcatcgt tggtacttgg cttgttctgc acacccttag
    86581 cagtagcttc tcctgcttgg tcgtttaata caatttctaa tacatctcct gcaaaaagtt
    86641 gattttctgg gatagaaaga acaaattccc ctgtatcatc aatagttgtt tctgacaaaa
    86701 cagcttgatt ttttttcaat gaaaccaagg ctcctgcttc acctgtacct gtgatcgtgc
    86761 gagaagctgc attgatcaat gtggtactta aattagcagg ttcaggagga atcacatcga
    86821 ctgtcgtttt ggcagagtcc agttctgtca cttcttggcc acctcttact tttttagcag
    86881 caacaacttg cacttgatcc tccgttttta atctctcatc attgggtact tgaacttcga
    86941 acaagccgcc ttgttcgcct tctccccatg ggttatatcc tgccccttca ttttcatctg
    87001 tttgtccttg cgtgagagca gtaatttcta cagatgattt cgtcgtatct gcgtaagtaa
    87061 tacgtaaagt cacttctact tcgcctgtcc aagcatctct tggctttgcc tcgacacctt
    87121 cgggaacaac gacatgccca tagatttttt tatctgcatt cgttggcact cttaaggatt
    87181 caatcatcgg gagctgatta ttggcactga ttcgattata atttttcatt ccggcacctg
    87241 tctgagcaaa ttcatttgtt aaacctgcac tagggcttga tacgaaattg cctaagtcgg
    87301 tcccattgat cgataagtct gtcatatcag aaaaataatc cgggtctttt tcaaagttat
    87361 cgaatgttgc gcctgttttt cgccataaag cgatttctga atgggcgatc tttaaagaag
    87421 aatctccatt tccttggaat acccagccgc ctatgccatt ggtctcgctt ccaatccgtt
    87481 tgttttggaa atcaaaatag gtaggagatt ctaagtccac attcaacaca tccccactga
    87541 tgatgccggt cttatcttcc cctgttttcc cgaccatgac taaataagtt ttttcacctg
    87601 ccgtaaaatt taaatcaata tctccagttg tatctacagt tgctccggaa tctgcgcgta
    87661 tatcgatatt tgatttttct ccagtgactg taaaatcagc tgaacctgga ctttctagaa
    87721 aaccagaagc gtcataaaat tggatcgctt gatttccttg attgagtctg ttcacgtaag
    87781 atttgccatc acctgtattt cttaccctca atgagcctcc attggttact gtcagctttt
    87841 gcgtaccatt ctcaaaacga actgcgctgg aacgcccact ctgcttatcg atgtcgataa
    87901 ctgatccggc tccttctacg atcaaagaaa ggccttttcc tacaaaacgc atcccattgt
    87961 tcccgggttg atcgtcatct ccagccattt tgaccgagat ttgtccacca cttgatacat
    88021 ggatttgact agaatctcct tgcaagcgaa atccgcccgt agttgctgta ttgatggtga
    88081 ttttcccacc attcgataca gtgactttcg atcctgaacc tctcatttgg atgattccgc
    88141 gattgttgtc attggtaata ttgatctttg tatttaccga aaattcgctt cccgaaccac
    88201 tgacttcaaa catgacatta ccaggtagcg tatcgactgc ctctccttca tcgctaacgc
    88261 catctgcccg atcataatca agagagacct ttgaaccgct taagatatgg attcctggcg
    88321 ctgtttttcc actaccagtc tcatctcctg aatctagaaa accgtagaat ttccctagat
    88381 acggtccata aagttgacta ccattgatca cattcaattg atagcttcta caaaaatagg
    88441 ctttacccgg agcggcattc agtccttcct tcactggttg gacatccaac acaccggaaa
    88501 caccatctaa tgtgacagtt gcacgaggag cgtaaatcag tcctaatttg gacccatcat
    88561 acaaatcaag tgtcccggta aattttattt ctcccgtaaa atgatatctg cttccccaaa
    88621 aatcggtcat ataagcaatg ataatggcat ttccatcgat atttggtgtc aatccacctg
    88681 gatgtgcagc tgttccttta aaattctgga actcgatcga ctgaggtatc tcattgatat
    88741 aaatatggtg tgtgccgaaa ttgtgagcga atccaccaaa atcaataacg atatctcgtt
    88801 tgatctctaa ttccctgtct aaagtcaaag gctgaatcag tcggatctta gttactgatt
    88861 cgtctgcgag aagctgcgcc agttcttctg ttgtggcagc ttcgctgtac ccatccgctg
    88921 aaacagctct tgccagtgcc gcttcactgc tatcagacgt ttgttcagct acttctgagg
    88981 tctcacttgt cttattttct tcttgccttt tattagtaga agcctcactt tgagattctg
    89041 tagtttcaga agtaatcgat tcttctgaaa aagtagtctt gtcaaaactt tgattctctg
    89101 attgcgttga ttcgtttgtt ttctctacat cggcaaaaac ggatgtcacc atcaagagag
    89161 ggaagacaaa caaaatcgac gcaatcagct tttttacaca ttgattcatt ctccaccatc
    89221 ctctctgacg ttttgacaat tttattttat cgttttaatc tatttccaat tgtactttca
    89281 tatttaaaat atgtattttt atggaaaaat ttttctatta ggtgtaaatt tcttttttgt
    89341 acaaaaaaaa ggctgtgaca aaagtcttgt cacagtccct tatcccgaac aagcggtgtt
    89401 ctcccgccaa ctcctcggtc acaacctcca ttttaacaat aaacctgtaa atgtgagggc
    89461 aatactttga ttgtcacagg taatttatcc ccttcatctc catcaacatt cgtcgtcaat
    89521 tcttcctcat cagctaatga cacaactaat tgctcacaag taaggtaggc tagatttttc
    89581 gtagattcat ctactccttt taataggtct ggcaatgttt taagcgtatc gatcaaagaa
    89641 gaatctttta aataaaccaa atggagctta ccatcatcca cttttgcatt tggaagtaat
    89701 gtttcaaaac cgccgactga gttagttagt cctatcagca aggtactgct ctcaatttct
    89761 tccttctttc catcaacttc tacgtgaaac gagtaggatt gtgtggaagc taactgtttg
    89821 attcctgaca tgaaataagc tagttttcca aatttcgtct tcttctccgc atctacatca
    89881 ttgattgatt cagggataga gccaattgcg acgacattca taaaatagtc gtcatttatt
    89941 tttccaatat ccaatggctt gactgattca atcgaaaaat gattgatcgc ttcctcaggt
    90001 tctagcggta tccctaatgc tcgagccaag tcattcaccg tacccaatgg gaaaaatccg
    90061 aaatttggcc gatgttcttg ttcagcgatt ccactgattc cttcgttgac tgttccatct
    90121 ccgcccatga caaacacact atgataccct tccgtagccg cttcgcgagt aaagtttttt
    90181 gcatcccctg ctttttttgt atgcaagacg accacttcat caaacaccga ttccaatttt
    90241 gctatcgcta attgctcaaa ttcctttgct tgttcaccgc ctgaactggg gtttaccact
    90301 aataaaactt ttttcatcac tttctttccc ttctgattga tttctttaat ataacgatag
    90361 cataaagaaa aaaattaggc tgtgatgaag tactgttcat gaaacattca tttatttttt
    90421 gacaagataa aacatccata ctatgaaact gaggaaaatt aaaacaatga tataggaaat
    90481 aaaagaaaat gataggcatt gtatacctaa taaagtaaaa atcttaggtg gcagataaaa
    90541 acacaaaaat agcaagagaa tgtaatagcg tttcttccac tttttgttat cagaccttat
    90601 agcgatcaga ggaataccaa atgcataact gaaaaactct tgatgtactg ttaatatgtc
    90661 acggccttga ataataaatg cgacaatccc cgctataatt agtgtgccta acaccaaaac
    90721 ggaaaattga tgaatatatt ttatatacaa atgatccatt gtacttcctg cctttttatt
    90781 tgtgagaaaa acaaatccgt atacgtgaat aacttctaga aataaaagaa atttgcaaaa
    90841 ccactccatt tatctacttc tacgtgcatt ttttgatatt gttttcttta tttaagatta
    90901 tacagaaaaa tatctagggt cgctggattc taagtaaaaa aaatttttaa aataaaaaga
    90961 actaaatcaa gtagtaatta aactactgtt gatttagttc taataaaaag atttagatga
    91021 acagttttat tgatttaaat agttcatatt ttttatttat accgcttatt tactacttgc
    91081 tgtactagaa tctgaagtga atgtactcaa aacattttca aagtctttgt ctttgatttt
    91141 tacattagcg tctttcaata cttcgccaat tactttattc tggaaggtac tgtcacttaa
    91201 ttttgtgtct gttgcaattt ctttcaattc ttttttgtat ttatccatgt cgttgccttt
    91261 gttttggttt ttcaccattt taaccacata atattccgta gtataagttg aagcattggt
    91321 agaagtgatc acatcagaaa cttgaccatc tttcaactta aaggctgctt ctttgacttc
    91381 tgccggaacc gttgtagtag tggaatcaaa tttcactttt ccgccatctt cttttgtcgt
    91441 agtatcagtt gacttgtctt tggctaattt agagaaatcg tctcccttat cagcagcttt
    91501 cttcacatct tttgcatcat cttcacttgc tacttggata atttgagctt ccacttctgg
    91561 atggaaagat tcccaagccg tttttaaatc ttcatcggtc aatttgatat gtttctttag
    91621 accttcttga aaggctagac tttgtttgat actgtctttg aatgtttgtt ctgtgtaacc
    91681 tgcagatttc aattgtgaat caaatgaatc acccaattgt ttctttgttt gatcatattg
    91741 agaatcgatt tctttggttg atacgtcatc tccatattta tcttcaaata cttgataaac
    91801 gatcaactgt tgcacagcgg aatctgctcc ttgcattttt ttcaagctat ccattacttc
    91861 ttgttcgctg attgtaccgc ctttataact aacggctgtt ttttcaccgg cattcgtaca
    91921 gcctgacaat aagccagtgc ctagtacgat ggcaagtgct aaaaatcttt ttttcattta
    91981 tcaattctcc tacttttcgt tttttgcgaa ttgctaaaaa caaaggtgtt caagatgaaa
    92041 atcatcaaga acacctttac taatctgctc gatacgtcct gaatagatat aaggctacac
    92101 aatccagaaa gttcgctcag cagaataaat gtcaagtagc acatcacacc ttaatatact
    92161 acttcttttg ttaccgtttt tcaagtctat cttgcgttcc gtatttaacg taactaattc
    92221 ttagaacaaa tgttatcgat tttgtttttc ttcttccgct gctgggatat tcaaatcaga
    92281 cacttttatg ttcgattttc cagacatttt tttgttgttt ttattatgat atatttttat
    92341 acaactaaaa atgaatatat taaaactacc aaaaataact tttaacgctg tttcattata
    92401 tgttttttct attttatata aacttttgga tacttaatac caaccggttg gattgtacca
    92461 acatgagaat gtgtcagttc tatttcctgt cgcacttgca taggcccata ctccttttgt
    92521 tgcatttgct gatcgaatag agtttccaac tttcgctttt gcaccgtgac gattatagac
    92581 acgactatag tggttagaat gacctgtttt tctcgtacaa gttgtatcac tataataaac
    92641 ccatcttcca gagctatgat taattgctgt tctagaaatt tcccggtcta ctggtaaatt
    92701 tgacttaata atattacctt tagcatcaaa atgaatctct cctggcttta aagatttgta
    92761 atagatttca ccgtgaactg aatttgcttc cacttcagat gacatagcgt ttcctccaac
    92821 aaaacctatc cctagtgcac aaataataac tgcttttttc ataaaacgac atcctttcct
    92881 ttttgatttt taaagcatga tcttcttgtt tcctattttg gtcagatatg gatcatgcgt
    92941 gactacgata actaacgtac cttgggaagc ttgttgcgat aagatttcaa ctactttatc
    93001 cttatttctt ttatccaatg acccagtcgg ttcatcggct aaaatgattt tgctattctt
    93061 caataagact ctcgcacagg cgattctttg cttctcacca ccagataatg tgtagatagg
    93121 cgtacttagc ttcttgttta tatttacttt tttcaatgcc tcatactttg ctgttcgctt
    93181 atctgaaaca tttaaattcg aaaacttcaa tccaatatct aaattaaaat cgattgtttc
    93241 atattcaatc aacccaaaat cttgaaaaag aaaagatatg gtatttcttt ttatcaagcg
    93301 cttctctctc ccagttaatt gtttcgtctc ttgatcgaac aaatagaatt gtcctgaact
    93361 gaactgatca ttcaatccta atatattcaa taacgtactt ttacctgctc cactttctcc
    93421 aacaacagtc acaagatccc cagcatccgc agtgaaacga tccaaatgaa gaatcgtttt
    93481 gtttcgaatg atttttttcg caccttttat cactatcaac ggctccaatt gttaacctcc
    93541 attcatcagc aataactgac ttttcttttc tgtagacaaa ataaaaacaa ctgaaagaat
    93601 aaaatcaatg aagctaaaga aaaaaatatt aaaaagatat ttaggctctc tttctataag
    93661 aaaaaggaag attacacttg tcgttcccca tttgatgagg ttcatcatga agaaatcttt
    93721 atacgtttca aagagcgaat aaccacttga acgaaagata gcgattttcc gacaattgta
    93781 gacaaaatat atgcataaca tgacatagct caacaagaag aaagaaaaga aagtgagtaa
    93841 aaatatctgt atcaagtaat gaaatgatct gcttaacact ttgacagcta tctcttcagt
    93901 ctgagtatac ggaaatgata actgcaagtt atcacgtaac tgactttctt caatcagctc
    93961 aaataacctt tctttcgaca aagagcctat cttgatcttt aacggtggat agatttctcc
    94021 gctgagaata tttctttcca aatacatact gtttttcaat gtcagtattt caacaaccgg
    94081 ataatgttcg atccagggga tagaaggaat aaatgtataa atgggttgat tgttttttat
    94141 aaatagaaat ttcggttctt tttcactgat ttcttgataa tattctgtta tttgcgccag
    94201 gtcatttttt aaatctgtat gtctatatcg ttcagggatc aatataacag ggtgcgtttc
    94261 tttttcggtt atttggatca accttccaga gacatcaatc aaaggaaatt tcttaagata
    94321 attcagattt atttttatcc ctctgccaaa ctgttcattt tcttcattca agtaatctga
    94381 tacattgact aatatacttc cgtttttatt caaagtttca tataattcct gatctgctgc
    94441 tgatgcaaaa cgattggaat aaataaaatc cacgtggttt ttcccgatgg ttactggata
    94501 aaatacatga tagtcctcac cagcgatttc ttttggtggt tcatgggaaa cagctaactg
    94561 tgaagaagaa aaaacgatag ttgctaattc gacattggca acggtcaaaa gaagagaaaa
    94621 caacaatcca aatgtaaaaa gaatgtattg gatatagttg aacgcttctc ttaacgaagc
    94681 gattttttca actaataaaa gagaaatcaa agagatacca tatattccgc tgaacaagaa
    94741 aacgtacatc tggaacaaat aaagaaattg ctccttataa tacataaaaa taaaaccacc
    94801 aatgattcct gcaattatga atgtaataat gattttcttt ttccccaata aacaccacaa
    94861 tacttgatgt aatgaaaagt cattattcaa caataaactg atttctttat tcatcaataa
    94921 gaaaaaggat gataacaaaa ggaataaaag aatcaatcca atagttaaat acactcgata
    94981 attatatacg tctgtatttg aaataaccga atacgaatag ctattttcaa agtcttcaaa
    95041 aatattagtg gcataatcag tgtgaaatgc ttgattgaat cgatcagtga atagtgaaat
    95101 gaaccgttca taggcttctt tttctctcgt catcaagaaa aattcacctt caaaatcttt
    95161 tattttgatc gattcttcaa tggacgttac gcgaaaggag gtattagaat agggtacctt
    95221 ctcgtgagaa gatttgacat ccccttgata atacaatgtc atttcaagct ttggctgtat
    95281 cttgaagttc caagatgtat ctacttcatt ggattcattt actgtttttt tcatataaga
    95341 aagctcagtt tctgatgaga cattttcaaa taccatgatt agctgctcat attcttcttg
    95401 cccaataaaa tgttgtggca atcgaatcgg agtataagta tctgtttgat ggaaaaattc
    95461 atttgtccga tagagtacct gtttatttat actaaccaag gcaaaaccac tcatgatacc
    95521 ggtcactatg attgtgagta aaactgtgaa cttttttttg attatcacca ctctccctta
    95581 cttaaatgat tctttgataa aatcataccg tttttcatca aaaaaacgta tctatcaagt
    95641 gtataggtca tgtagaataa atctatatac tgtagaatcg aaaggagaag aagatgaaca
    95701 ccggagaaaa aatacgaact taccgcagaa attgtaagct tacgcaaaaa gaattaggcg
    95761 aaaaaattgg tgtttccgat aaaacgattt ctagttggga aaattctcgt acaatgccag
    95821 accttgaaat gctgtcactt ttacatcata ctttaggtct gccgattgat tttccttcta
    95881 ttgaatcagc taccgaatca atagaaccaa cattgccaga tgaacctctt gttaacaaga
    95941 aatcttattc atcaaaacaa cccttctcac tcaaaaagac actatctttc tttctgctcg
    96001 tcttttgttt ggtctatctt tttcttatca attatcaata caaaaatgaa acgatcgatc
    96061 gattcaatcc ttttttgaaa ccacaaatcg gctataccac actccctgta ggatacgtgg
    96121 acaattccat cgaacgttgg gtatgtaatg atatctttgg ccatggtaca tggctgtctt
    96181 ttcacgctgg agaggtagaa aaagagaaaa accatgctgt aatcaaacac aaaggaaaac
    96241 acgtcatgaa cgttcgcctg ctcacttggg aagccattcc ctcagattac caagaaatcc
    96301 tcagccaaga ctatgacgac gccttaaaaa gaagccctca ggagccagat aggcattaag
    96361 taggagatga acgtagagat agaaaaaatc aatgcacatg atcttatcca aaaaacaggg
    96421 gtacaaatta attgaaaaag ccttgagatg aaagttccta aataaaaaag ttcagaatga
    96481 taggtatttc tggcttatag tataatattt acgccacagc ctcccaatga ttctttttgg
    96541 aatcataatc aaggatggac attcacaaaa atattttgct cattcgatcc gaatagatta
    96601 acgaccaatc tagtaagtaa tatagattgg tacgtagtca agctgcacat aatttagatc
    96661 aattttagtt cttttttata tttctatgat ctgctcattt acttttatat gatggcttac
    96721 agtaacataa ataaatatga taatcgctgg tagtttatcc aagagtactc aataaaatac
    96781 aaaatggatt gttcaagcgc ctatcataat gataaaatga aacaaataaa cgatacaagg
    96841 aggaagagac tttgagtaat ggcagaacaa ttttttcatt gtaaaaattg ttcagttgtt
    96901 aatctatggg atttcggtag catgggcatt tttttataga ggaatcacac caacctggcc
    96961 gttttatctc ttgttagtgg gaatattagt aggaaatttt gcccctcttc actatcgtac
    97021 gaactttttt ccaactgatt ctggcctttt tcttaaaaca aagacgcgaa aattagaaaa
    97081 cattattgaa atgacaatta cctgtataat cattttctta gttatattcc taaacgtctt
    97141 ctaataagaa tctcttaaaa ttagcttgtt acagttagtt acctagttta tataacacag
    97201 ttatcttatc ttccttatca acatcttttg ccaactcttt gtcttaaatt cgaaacatat
    97261 aagcagagct acgaacacca agactgtttc ggctctgttt tttgcatcaa attcactctt
    97321 atatagctga taatctcggc tctttaaaag aaattatttt cgcttcattt tattataaaa
    97381 aggctaggaa ccttgatgtt atcaggttcc tagcctttat ttaagtatta ccccacagac
    97441 ccttccatat agatttttaa attacacact agtttaaact aaaacaaaca aggaaacact
    97501 taccatttaa tcataaaatt agctcatatg aatatattag aatgtaaaat agactggtca
    97561 aaatctggtc aaaaaagagg actaatacag gtagtcctca gactgtagac aaagtccatt
    97621 ttatggatga t
//
LOCUS       DAPBAF010000004        85354 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.004, whole genome shotgun sequence.
ACCESSION   DAPBAF010000004 DAPBAF010000000
VERSION     DAPBAF010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 85354)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 85354)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..85354
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.004"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            85..972
                     /locus_tag="RD451_000314"
     CDS             85..972
                     /locus_tag="RD451_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HDT7565610.1"
                     /translation="MQELKTRSARHHRPKRKMVINKKAIAPLIGTSLLVGPMMVTAVP
                     QHVHADEQGSQTVADPQAFIDQIGWSASEVAASNDLYASVMIAQALLESAYGTSGLAS
                     APNYNLFGVKGSYNGQVVYMATKEYVNGQWVTMNEPFRKYSSYWESFQDHANVLRSTS
                     FSTGDYHYAGVWKSNTTSFYDATAYLTGRYATDPNYGAKLNSLINTYNLTRFDTPSTG
                     SATTTTSTTTTTTTTTSTSSSSTTDVNTNNGQTYTVVSGDTLWDIAQKFGMSVDDLMA
                     KNGMSMSSYSLLVGQELNV"
     gene            1112..2038
                     /gene="cysK"
                     /locus_tag="RD451_000315"
     CDS             1112..2038
                     /gene="cysK"
                     /locus_tag="RD451_000315"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HDT7565611.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            2274..2720
                     /locus_tag="RD451_000316"
     CDS             2274..2720
                     /locus_tag="RD451_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HDT7565612.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            2993..4345
                     /locus_tag="RD451_000317"
     CDS             2993..4345
                     /locus_tag="RD451_000317"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidase"
                     /protein_id="HDT7565613.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSNPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQAALGEIETAQ
                     "
     gene            4516..4803
                     /locus_tag="RD451_000318"
     CDS             4516..4803
                     /locus_tag="RD451_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565614.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
     gene            5029..5472
                     /locus_tag="RD451_000319"
     CDS             5029..5472
                     /locus_tag="RD451_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDT7565615.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(5478..6662)
                     /locus_tag="RD451_000320"
     CDS             complement(5478..6662)
                     /locus_tag="RD451_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HDT7565616.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            6930..7628
                     /locus_tag="RD451_000321"
     CDS             6930..7628
                     /locus_tag="RD451_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HDT7565617.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            7635..8312
                     /gene="nth"
                     /locus_tag="RD451_000322"
     CDS             7635..8312
                     /gene="nth"
                     /locus_tag="RD451_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HDT7565618.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(8438..8971)
                     /locus_tag="RD451_000323"
     CDS             complement(8438..8971)
                     /locus_tag="RD451_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565619.1"
                     /translation="MVLNNFLKEGFILSYLIVCLIIIICLHHLFLSKTIPRYSKNKKA
                     EKFCLLLNKFTLIAPILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFL
                     MSLKPPKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYI
                     GYFPNKNNNFYFYRNKL"
     gene            complement(9268..11649)
                     /locus_tag="RD451_000324"
     CDS             complement(9268..11649)
                     /locus_tag="RD451_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HDT7565620.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(11639..12286)
                     /gene="recU"
                     /locus_tag="RD451_000325"
     CDS             complement(11639..12286)
                     /gene="recU"
                     /locus_tag="RD451_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HDT7565621.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            12350..12889
                     /locus_tag="RD451_000326"
     CDS             12350..12889
                     /locus_tag="RD451_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HDT7565622.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            12979..13398
                     /gene="gpsB"
                     /locus_tag="RD451_000327"
     CDS             12979..13398
                     /gene="gpsB"
                     /locus_tag="RD451_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HDT7565623.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            13420..13787
                     /gene="rnpB"
                     /locus_tag="RD451_000328"
     ncRNA           13420..13787
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="RD451_000328"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            13996..15162
                     /locus_tag="RD451_000329"
     CDS             13996..15162
                     /locus_tag="RD451_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HDT7565624.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            15208..16704
                     /locus_tag="RD451_000330"
     CDS             15208..16704
                     /locus_tag="RD451_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HDT7565625.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTRKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     SLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            16785..17468
                     /locus_tag="RD451_000331"
     CDS             16785..17468
                     /locus_tag="RD451_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HDT7565626.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
     gene            18113..19303
                     /locus_tag="RD451_000332"
     CDS             18113..19303
                     /locus_tag="RD451_000332"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HDT7565627.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
     gene            19405..20358
                     /locus_tag="RD451_000333"
     CDS             19405..20358
                     /locus_tag="RD451_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HDT7565628.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSGNVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            20427..21776
                     /locus_tag="RD451_000334"
     CDS             20427..21776
                     /locus_tag="RD451_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDT7565629.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(21959..22282)
                     /locus_tag="RD451_000335"
     CDS             complement(21959..22282)
                     /locus_tag="RD451_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565630.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            22411..23574
                     /locus_tag="RD451_000336"
     CDS             22411..23574
                     /locus_tag="RD451_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HDT7565631.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            23644..24993
                     /locus_tag="RD451_000337"
     CDS             23644..24993
                     /locus_tag="RD451_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDT7565632.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(25038..25469)
                     /locus_tag="RD451_000338"
     CDS             complement(25038..25469)
                     /locus_tag="RD451_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7565633.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            25857..28499
                     /gene="alaS"
                     /locus_tag="RD451_000339"
     CDS             25857..28499
                     /gene="alaS"
                     /locus_tag="RD451_000339"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HDT7565634.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKEHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            28699..29295
                     /locus_tag="RD451_000340"
     CDS             28699..29295
                     /locus_tag="RD451_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDT7565635.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            29417..30565
                     /locus_tag="RD451_000341"
     CDS             29417..30565
                     /locus_tag="RD451_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HDT7565636.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(30603..31016)
                     /locus_tag="RD451_000342"
     CDS             complement(30603..31016)
                     /locus_tag="RD451_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HDT7565637.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            31095..31526
                     /locus_tag="RD451_000343"
     CDS             31095..31526
                     /locus_tag="RD451_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HDT7565638.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            complement(31625..31858)
                     /locus_tag="RD451_000344"
     CDS             complement(31625..31858)
                     /locus_tag="RD451_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock domain-containing protein"
                     /protein_id="HDT7565639.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            32041..33711
                     /locus_tag="RD451_000345"
     CDS             32041..33711
                     /locus_tag="RD451_000345"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HDT7565640.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            33858..34244
                     /locus_tag="RD451_000346"
     CDS             33858..34244
                     /locus_tag="RD451_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565641.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            34231..34929
                     /locus_tag="RD451_000347"
     CDS             34231..34929
                     /locus_tag="RD451_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HDT7565642.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            34934..35398
                     /locus_tag="RD451_000348"
     CDS             34934..35398
                     /locus_tag="RD451_000348"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HDT7565643.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            35395..36306
                     /locus_tag="RD451_000349"
     CDS             35395..36306
                     /locus_tag="RD451_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HDT7565644.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAHLPEVFEKTLEKLRKNIAF"
     gene            36541..37080
                     /gene="pyrR"
                     /locus_tag="RD451_000350"
     CDS             36541..37080
                     /gene="pyrR"
                     /locus_tag="RD451_000350"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HDT7565645.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            37094..38377
                     /locus_tag="RD451_000351"
     CDS             37094..38377
                     /locus_tag="RD451_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HDT7565646.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            38390..39316
                     /locus_tag="RD451_000352"
     CDS             38390..39316
                     /locus_tag="RD451_000352"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HDT7565647.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            39335..40615
                     /locus_tag="RD451_000353"
     CDS             39335..40615
                     /locus_tag="RD451_000353"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HDT7565648.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            40620..41696
                     /gene="carA"
                     /locus_tag="RD451_000354"
     CDS             40620..41696
                     /gene="carA"
                     /locus_tag="RD451_000354"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HDT7565649.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            41701..44886
                     /gene="carB"
                     /locus_tag="RD451_000355"
     CDS             41701..44886
                     /gene="carB"
                     /locus_tag="RD451_000355"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HDT7565650.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            44940..45716
                     /locus_tag="RD451_000356"
     CDS             44940..45716
                     /locus_tag="RD451_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HDT7565651.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            45713..46645
                     /locus_tag="RD451_000357"
     CDS             45713..46645
                     /locus_tag="RD451_000357"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HDT7565652.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            46642..47358
                     /gene="pyrF"
                     /locus_tag="RD451_000358"
     CDS             46642..47358
                     /gene="pyrF"
                     /locus_tag="RD451_000358"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HDT7565653.1"
                     /translation="MNQLDQRPIIALDFSTRQEVEDFLRFFPKEEKLFVKIGMELFYQ
                     EGPEIVRYLKEAGHNVFLDLKLHDIPNTVEKAMRGLAKLGVDLTCVHAAGGIRMMEAA
                     MRGLEEGTPEGGKRPLLLAITQLTSTSEEEMHADQLIEVSLEKSVIHYASCAKKAGLD
                     GVVSSAWEVEAIKEMAGDEFVCLTPGIRPEGTVAGDQTRVVTPSQAKKIGSTFIVIGR
                     PITQSTNPYKAYQTIQTEWS"
     gene            47365..47994
                     /locus_tag="RD451_000359"
     CDS             47365..47994
                     /locus_tag="RD451_000359"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HDT7565654.1"
                     /translation="MNVEQSIAKDLLEIEAVFLNPSNPFTWASGIKSPIYCDNRITMS
                     YPKVRKEIAKGLASKIKEAYPEVQVIAGTATAGIPHAAWVAEILDLPMVYIRSKAKDH
                     GKGNQIEGRIFEGQKMVVIEDLISTGGSVLEAAEAAKREGADILGVAAIFTYELPKGK
                     ANFEKAEIPLMTLTNYSVLIEAALEDRYIDEQELTLLKEWKKDPENWQI"
     gene            47982..48296
                     /locus_tag="RD451_000360"
     CDS             47982..48296
                     /locus_tag="RD451_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565655.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            48334..48975
                     /locus_tag="RD451_000361"
     CDS             48334..48975
                     /locus_tag="RD451_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HDT7565656.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            49018..49710
                     /locus_tag="RD451_000362"
     CDS             49018..49710
                     /locus_tag="RD451_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HDT7565657.1"
                     /translation="MDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKGEETK
                     IEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSEHIIN
                     GKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVNPDVF
                     FPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPIQPLN
                     GREIYYFEEFEQ"
     gene            49707..50609
                     /locus_tag="RD451_000363"
     CDS             49707..50609
                     /locus_tag="RD451_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDT7565658.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(50767..52473)
                     /gene="efbA"
                     /locus_tag="RD451_000364"
     CDS             complement(50767..52473)
                     /gene="efbA"
                     /locus_tag="RD451_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein EfbA"
                     /protein_id="HDT7565659.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITTMKQ
                     NR"
     gene            52663..53286
                     /locus_tag="RD451_000365"
     CDS             52663..53286
                     /locus_tag="RD451_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565660.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            53736..54785
                     /locus_tag="RD451_000366"
     CDS             53736..54785
                     /locus_tag="RD451_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDT7565661.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            54782..55663
                     /locus_tag="RD451_000367"
     CDS             54782..55663
                     /locus_tag="RD451_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7565662.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            55666..56436
                     /locus_tag="RD451_000368"
     CDS             55666..56436
                     /locus_tag="RD451_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDT7565663.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            56715..57569
                     /gene="aroE"
                     /locus_tag="RD451_000369"
     CDS             56715..57569
                     /gene="aroE"
                     /locus_tag="RD451_000369"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HDT7565664.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            57747..58910
                     /locus_tag="RD451_000370"
     CDS             57747..58910
                     /locus_tag="RD451_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HDT7565665.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGGQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            59027..59437
                     /locus_tag="RD451_000371"
     CDS             59027..59437
                     /locus_tag="RD451_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDT7565666.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            59611..61839
                     /gene="topB"
                     /locus_tag="RD451_000372"
     CDS             59611..61839
                     /gene="topB"
                     /locus_tag="RD451_000372"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HDT7565667.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            62010..62294
                     /locus_tag="RD451_000373"
     CDS             62010..62294
                     /locus_tag="RD451_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565668.1"
                     /translation="MGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAYSPTLILSTLTA
                     GAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQYFG"
     gene            62454..62690
                     /locus_tag="RD451_000374"
     CDS             62454..62690
                     /locus_tag="RD451_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HDT7565669.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            62687..63086
                     /locus_tag="RD451_000375"
                     /pseudo
     CDS             62687..63086
                     /locus_tag="RD451_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
     gene            complement(63753..64697)
                     /locus_tag="RD451_000376"
     CDS             complement(63753..64697)
                     /locus_tag="RD451_000376"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HDT7565670.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(64993..65937)
                     /locus_tag="RD451_000377"
     CDS             complement(64993..65937)
                     /locus_tag="RD451_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7565671.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            66158..67372
                     /locus_tag="RD451_000378"
     CDS             66158..67372
                     /locus_tag="RD451_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDT7565672.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASICGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            67394..69409
                     /locus_tag="RD451_000379"
     CDS             67394..69409
                     /locus_tag="RD451_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HDT7565673.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEEAFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(69492..70865)
                     /locus_tag="RD451_000380"
     CDS             complement(69492..70865)
                     /locus_tag="RD451_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HDT7565674.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(70891..71175)
                     /locus_tag="RD451_000381"
     CDS             complement(70891..71175)
                     /locus_tag="RD451_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDT7565675.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(71177..73192)
                     /locus_tag="RD451_000382"
     CDS             complement(71177..73192)
                     /locus_tag="RD451_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HDT7565676.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(73371..73676)
                     /locus_tag="RD451_000383"
     CDS             complement(73371..73676)
                     /locus_tag="RD451_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HDT7565677.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(73765..74796)
                     /locus_tag="RD451_000384"
     CDS             complement(73765..74796)
                     /locus_tag="RD451_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDT7565678.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            75003..75878
                     /locus_tag="RD451_000385"
     CDS             75003..75878
                     /locus_tag="RD451_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDT7565679.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(76030..76872)
                     /locus_tag="RD451_000386"
     CDS             complement(76030..76872)
                     /locus_tag="RD451_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HDT7565680.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(76964..78841)
                     /locus_tag="RD451_000387"
     CDS             complement(76964..78841)
                     /locus_tag="RD451_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HDT7565681.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVGKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(78838..80259)
                     /locus_tag="RD451_000388"
     CDS             complement(78838..80259)
                     /locus_tag="RD451_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HDT7565682.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(80262..83651)
                     /locus_tag="RD451_000389"
     CDS             complement(80262..83651)
                     /locus_tag="RD451_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HDT7565683.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            83908..85299
                     /locus_tag="RD451_000390"
     CDS             83908..85299
                     /locus_tag="RD451_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7565684.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
BASE COUNT        27330 a        15082 c        17574 g        25368 t
ORIGIN      
        1 aattaaaagt ataatttaat taattaagtt tgttttaaga agagaacttt ttattaagtt
       61 tttttatttt gaggaggaat ttgaatgcaa gagctgaaga cccgcagtgc ccggcaccat
      121 agacctaaaa gaaaaatggt gatcaataaa aaagcgattg ctcctttaat tggaacgagt
      181 cttttagttg ggccgatgat ggttacagcg gtaccgcaac atgttcatgc agatgaacaa
      241 ggatctcaaa cagtcgctga tcctcaagcg tttatcgatc aaatcggctg gtctgcgtca
      301 gaagttgctg caagtaatga cttgtatgct tcagtcatga tcgctcaagc gttgttggaa
      361 agtgcatatg gcacttccgg attagctagt gcgccaaatt ataatctatt cggtgtgaaa
      421 ggaagctata acggacaggt cgtttatatg gcaaccaaag aatatgtaaa cggacaatgg
      481 gtaacgatga atgagccatt ccgaaaatat tcttcttatt gggaatcctt ccaagaccat
      541 gcgaatgttc ttcgttcaac cagtttttcc acgggcgatt atcattatgc tggcgtgtgg
      601 aaaagcaata caacaagttt ttatgatgca acagcgtact tgacaggtcg ttatgctacc
      661 gatccaaatt atggggccaa attgaactca ttgattaata cttataattt aacccgtttt
      721 gatacgccat caacaggttc ggctacaaca accacaagta caacaacaac gactactacg
      781 acgacttcaa cgtcatcatc ttcaacaaca gatgtaaata caaataatgg tcagacatat
      841 acagtcgtgt caggtgatac gctatgggat attgcacaaa aatttggcat gtctgttgat
      901 gatctaatgg cgaaaaatgg catgtctatg tccagttatt ctttattagt tggtcaagaa
      961 ctaaacgttt gatttagata aaaaggcaaa gaaattacca tatatggtat atctttgtct
     1021 tttttttgct agtcaaagac gaatcactcg ccataaatga acagattgta ttatgataag
     1081 taagaagagc aaagacaagg aggaattgaa gatgacagct atctataact cagtcaccga
     1141 attgattggc aaaacgccaa tcgtcaaatt aaataaaatc gtaccagaag attcagcaga
     1201 tgtttttgta aagcttgagt tttttaatcc aggaggaagt gtaaaagatc gtattgcttt
     1261 aagtatgata gaaaaagcag aacacgatgg tctactgaaa ccaggtgata ctatcattga
     1321 acctacttct ggaaatacag gaatcggatt gtcgatggta ggagttgcaa aaggatataa
     1381 agtaatcatc gtgatgcctg agacgatgag tatcgaaaga cgtttattga tgaaagggta
     1441 cggcgcagag ttgattttga ctcctggtgc ggatggtatt tctggatcaa tcagagaagc
     1501 agaacgtttg gcaaaagaaa acggctactt tttaccatta caatttgaaa atgaagcaaa
     1561 tcctcttgtg catgagaaga cgactggtcc tgagatacat caagcatttg gagtaaatgg
     1621 cttggacgcg tttgttgcag gtatcggtac aggaggaacg atcactggcg ctggccgaga
     1681 attaaaacgt gtgtatccga aaatcgaatt aatcggggta gaaccagcag aatctgctat
     1741 tttagaaggg aaagaagcgg gacctcacaa aatccaagga atcggtacag gttttgttcc
     1801 taaaacactg gatacttctg tgtatgataa agtcctttct attagtggag acgaagcgat
     1861 ggaaacagct agagaagttg ggcgaaaaga agggatttta gtaggcatct catctggcgc
     1921 tgcaattgct gccgcgctaa aagtcgcaaa agaattagga aaaggcaaga aggtattagc
     1981 tgtggttccc gacaatggtg aacgttattt atctacagcc ctttaccaag agatataagg
     2041 cacttggttt ttctccagat aggtttatgt aaaaaacttt taaagatgaa aagaacacac
     2101 aaaaatttat gatgagaaaa attatttgaa tagagacgta gaatagtgaa cgcgactgtt
     2161 ttacgtcttt tttcattaaa atacaataaa attgaatttt cttttcatgt taagtggatt
     2221 ttaaaatgta aaaatagtat gataagacga gaataacaac gtggggtgtt tacatggaaa
     2281 ataagttagt cgaagaggtt atcgaaaagt taaaaaaaga gaacattcga atcacacctc
     2341 aacggtacgc ggttttagaa tatttgattg aacatcattc ccatccaacg gctgatgaga
     2401 tttataaagc acttgaacat cggtttccaa atatgagtgt tgcgactgtt tacaataacc
     2461 ttcgcttatt tacttcgatt ggatttgttc aagaaatgaa gtacggcgat gcttctagcc
     2521 gatttgattt cagttcaaag cgtcattatc atgtaatttg tgaaaactgc ggtaagattg
     2581 ttgattttca ttacccaggg cttgaagata tagaaatggc tgcaagcaga ctgactgatt
     2641 ttgagattaa tgaacatcgg ttggaattgt atggactctg tccggattgt aaagagtcag
     2701 caaaaaaggc gcaaatgtaa aaacagtttc tacaagtgtt atacctaaaa aaagctagct
     2761 gtgtaaaaaa aacgctagct tttttatttt tttgtctttt attcacaatc ttagatataa
     2821 aagtgaatat tattaaaata agaatcttgt agatattggg ttcttatgct tgaaaaggaa
     2881 tgaaactaca aacaaacctt tgtgaattca caagcattaa actgttgtat ccgttttatt
     2941 tctgttatag tagttttgtc gaaggacaaa atgttaatcg gagggaccat aaatgaaagt
     3001 agtagtaatt ggctgtactc atgcaggtac tgcagctgta aaaagtattt taaaaaatca
     3061 tccagaagca gaagtgacag tatatgaaag aaatgacaat atttctttct tatcttgcgg
     3121 tatcgcactt tatgtcggcg gagtagtaaa ggacccagca ggcttgttct actcaaatcc
     3181 tgaagaatta tcttcattag gagcaacagt taaaatggaa cacgatgtaa cagacgtcga
     3241 tacagaaaat aaaacagtaa cggcaaaaga tctgaaaaca ggagaaacag aaacggtttc
     3301 ttatgataaa ttagtgatga caactggttc atggcctatt atcccaccga ttagtggaat
     3361 cgatgcgaaa aatgtactcc tatgcaaaaa ctacaatcaa gcaaatgaaa ttattgcaca
     3421 agcgaaagaa gcaaaacgtg tagtaattgt tggtggtgga tatatcggta ttgaattagt
     3481 agaagctttt gtcgaatctg gaaaacaagt gacattgatt gatggattag atcgcatctt
     3541 gaataaatat ctagataaac cattcacaga tatcttagaa aaagaattga cagaccgcgg
     3601 tgttactctt gcgctaggcg aaaatgttac tgaatttatc acagatgaag aaggaaaagt
     3661 gaaacaagta gctacaccaa cagatacatt tgatacagat atggtcattt tatgtgtggg
     3721 cttccgtcca aatacaaaac tgatcgaagg aaaagtagat acactgccaa acggggcaat
     3781 caaagtgaat gaatacatgc agacaagtaa tccagacatt tttgcagctg gagactctgc
     3841 agtagtcaac tacaatccaa gtggcacgca aaactatatt cctttggcaa caaatgccgt
     3901 tcgtcaaggt ttgcttgtgg gaaataactt gacagatcat aaaatggcgt atcgtggtac
     3961 tcaaggaact tcaggacttt acctatttgg ctggacgatc ggttcgacag gtgtgaccaa
     4021 agaaagcgca actttgaacg atctagaagt ccaagcgact gtatttgaag ataattatcg
     4081 tccagagttc atgccaacta ctgaaaaagt aatgatggag ctagtctatg aaaaaggaac
     4141 gaatcgtatc gtaggtgctc agttcatgtc caaatacgac attacacaat cagcaaatac
     4201 catgtcttta gctgttcaaa ataaaatgac tgtagaagat ctcgcacttt cagatttctt
     4261 cttccaacca cattttgacc gcccatggaa ttacttgaac ctacttgcac aagcagcgct
     4321 aggcgaaatc gaaactgcac aataaagaaa aagggttgtg acacaatttt gtcacgaccc
     4381 tctgtctttt tttgtgaaaa gtacaattag ttgtctttct tcgaattttt tgtcacaata
     4441 agcagcaaag ataaagctgt tacataaaag aacaagcagc tttatttgat tttgaaaaga
     4501 aaggtgagaa agaagatgaa taaagaatat tttgtccaac aagatgcatt tttagaagat
     4561 tataaaagtg cttcgaagaa attaacgatc aatattgatg agttggcaga tcaagtactc
     4621 tctcagttga atgaaacgca agaggaatat tacacgatgc cagcaaatga cgccaaagat
     4681 aatgtttctc atcgttttcc tttcagtaga cgcatctact cagatgaaaa tgacggcaca
     4741 ttgaatacag agtacacata tgaaggtcag ccatatgtgc tagaaactga tgatgatctt
     4801 taaagacagt ttttgaaaag gccgctcatc cttaagtgat gacaaaaaat catcacaatt
     4861 accgatgact gtctctttac tatcttttaa tcagaaaaag gggttatgac aagctttgtc
     4921 aacccctttt tttcttggtt tcagattggg ttttcctaca aaatattttt atctttgttg
     4981 aataggaaac aaaaaaacaa tataatgaaa gaaaaagaag gtgtagaaat ggataaaaga
     5041 caactgctaa tagaagaata tctggattta gctaatgaga ttattcatcg taataaacca
     5101 gaaatggaaa aagaatttgc aggatttact ctaaatgaac tagaagtgat tgaacatatc
     5161 gggaaaatcc ctgatcctaa cgtgacaaaa ttagcgaatg ctagttacat gactagagga
     5221 gccatcagta agctaacaaa aaaactgata gctagaggga tcataaacac ttatcaaagc
     5281 gaagagaata aaaaagaaat ctattttcaa ttgacgccaa tcggacaaaa aataaggaat
     5341 agacacgagc aactccatca aaaatgggta cagcgagatg ctactgtatt tgaaaatatg
     5401 tcaaaagaag aatttgacac agtatttcgt tttatcggtc gatacagaga atttatacga
     5461 agtagcaaat gaagctacta ttttttattg tagtgataat aggcaaaaat cataagcaaa
     5521 aatccgaata ccgtcggaag aaatggtgct gcagcataaa gctgtcctgc gattagcggg
     5581 ccgatgacgc gcgatagaga ttgtatactt tgggtaccgc ccattacaag accttgctgg
     5641 ttatctgaga cagaattgga tagttggcca ttgaatacag gagtaaaaat agaatcaccg
     5701 aaaccataac agataatccc aaataaaaac aaaatcggca gtagaagaat tccagataat
     5761 gtgatgaata gataggcgag gatttcactg aacatcccta ttcttgtgat ctgctgttct
     5821 gaaaattttt tgagcaatcg aggcataatg aacaattgcg agacagtatc caagattcca
     5881 atcaaagaga agcttaaacc aaccaaccca gccttccact gaaaggcgtc aatcgaaaat
     5941 tgagaaaaga tagattgaag agagccagct gccaaccaaa cagcaaaacc tgctgtcaat
     6001 aaaggaataa cggatgaaat cttgaataat tgttgtaatt ggtgaaaagg tcttacatgg
     6061 gagaaactta aatctactga acgttttttt attggaaggc tttctagcat aaatgtgtag
     6121 ccataaacgg catttaagaa agtaaagagt gctccaataa atataggaac agaattcccc
     6181 aactcagcta atagaccccc tataatagga cccagcgttg ttcctatacc gactaaagca
     6241 cccatccatc caaaaacttt ggttctttca ttaggttccg tgatgtcggc aaagtaagca
     6301 tataaggtgg agatttctcc tgccgtcaat ccttcaatga tacgaccaag gaacaacatc
     6361 catatcgaat ttcctaaacc aaaaagcaaa tatccgatac ttgatcctaa taaactgata
     6421 ataaggatcg gatgacgccc aaaatgatca cttaagctac cgagaatggg ggcagataag
     6481 aaggcagcta gagcataaac agacatgagc aaagtgatat agaaagcttg ctgatgtatg
     6541 gagtgagaat aaggcagcgt taaaaacgga agtacaggac tgacgatagt aaatcctaat
     6601 ccagtgaata agacagagac gtatccaaaa actttagaat gtttatttgt gaaactgtac
     6661 atgtaaaaac tcctttatgc aataatgtta acttggaaac aaaaatagtg tatagtaatt
     6721 ttgtttcctt gtcaacattc taaggaacag cgaaatctac ttaatttatt tattccgaaa
     6781 agtgaagata cgcatcaaaa acatgaacaa acaaaaatca agtagacgac attgtaaatc
     6841 tgaccgatca gtgaagtaaa tagaaaagaa acctgttctt gcttcccatg ttttttttac
     6901 gtatactgtg attgagcgga ggagaaatca tgttgaattt agaaaattac ttaagcgctg
     6961 gacaaacagt catatctaat cttttactta aaaattatca taggatcggt ctacaatctg
     7021 aagaattttt atttgttcta cagttgcata tggcacagct tgaaggagat actttccctg
     7081 atttgcagat gattgctatg gatatgggaa tcaaacaaga tcagattttt caaatactgg
     7141 atcgtctcgt aacaaatgga tttatcaaga tagaaacgac gattgtcaac ggtaaaaaag
     7201 cagatcgata taatctttac cccatctatg atctattagg tgagtattta aaaacacaag
     7261 aaaaaaaata cgaagaaaaa acacaagaaa aagaaatcca gtcagtgtat caattatttg
     7321 aacaagaatt tggacgcccg ctttcttcga tcgagttcca gcggatcgga caatggctag
     7381 aagaagacca ttatcagccg gaaattttga agctagcact gcgggaagcc gtattaaatc
     7441 aggcttatag ttttaattac gttgaccgca ttttgctatc gtgggaaaga aaaaatctac
     7501 gtacaaaaca acaagtggaa gaagaccaaa aacgaagaaa acagcagctt cttcaaagag
     7561 aagtagaaca gtcagctcaa caagaagaat tgccgaaagt ctcactgaaa aattggttgg
     7621 aggagtagcg gaatatgtta agcaaacaaa aaacaatgga agctctagaa acgatgtatg
     7681 gaatgtttcc cgaagcacat ggagaactca agcacaataa tccatttgag ttattgattg
     7741 cagtgatctt aagtgcccag gcgacagatg tatcagtgaa taaagcaacg ccagatttgt
     7801 ttgcctcttt tccgacaccc gatgcgttag cagaagcttc aatcgatgaa atcattctta
     7861 aaataaaaac gattggtttg tatcgaaata aagcaaaaaa catcaaagcg tgtgcacagc
     7921 agctgattga acgtttcgat gggcaagtgc caacgtcaag agaagaattg atgtctcttc
     7981 ctggtgtagg cagaaagaca gcaaatgtcg tattggggga tgcattcggg ataccagcaa
     8041 tcgcagtaga tacccacgtg gaacgtgtct caaaacgcct gaggatctgc aaactagatg
     8101 ctacggtcat ggaagtagaa gaaacactga tgcggaaagt accacaagaa ttatgggtaa
     8161 agacacatca tacactgatt ttttttggta gatatcattg cacggcaaga aatcccaagt
     8221 gcgaggtatg tcctttgcta tcaatatgtc aagatgggaa aaatcggatg cgtctaaaag
     8281 aaaaggcgct aaaaaagaaa ccacgcctgt agacgtggtt tctttaattg caaataaatg
     8341 tatgaattat cttgttatta tggagaaaag ctgtttcgtt tatctttttt gcatgaaaaa
     8401 gtaaatgtac atactcagta gctaggatgg taacttatta caatttattg cgataaaaat
     8461 aaaagttgtt atttttattg ggaaaatacc cgatgtagaa aataatgcct tccaatatac
     8521 ctataaaata agtccagtat tccaaaggat tatataaata agtgacgtat ctatctaaag
     8581 gtgtaataaa aatgataagt gataataaaa aaataccatt tataactaaa cataaactaa
     8641 tggatttggg cggtttcagg ctcatcagaa aaatatagat tctggtgaac aacaaccata
     8701 aaaaagtgag aatcattgca tgagagcttc tttccataaa ttttccttta agagtagtgc
     8761 ttaaaagtac agaaaaaata ataaatgcaa ggataggagc aattaaagta aatttattta
     8821 ataataaaca aaatttttca gcttttttat tcttggaata acgaggtatt gttttcgata
     8881 aaaaaagatg gtgcagacaa attatgataa ttaagcatac tatcagataa ctcaaaatga
     8941 agccttcttt caaaaaatta ttcaaaacca tatattgtat tttttatttg ataataacaa
     9001 tgggattatt aagaagtggc actaaataaa agactagtgt gtatttagcc gatttaatta
     9061 taaacaagta aatggataaa gtatatgtaa tgataaaaga aaaatggatt ttctaatttt
     9121 taagctaaat gttagatcac acatgtatat gctggatagt cttataaaaa atcatgtaat
     9181 acagcttggt acatgatttt tatttgtagc tgttttttac atagacacaa aaaagaaacc
     9241 acgcttgtag acgtggtttc ttttttacta tctgtttcca gaagctgagg tgctgctgga
     9301 tggtgtatgg tcatttgcag catccgctcc gctagttgct ggctcactgg aagaagcagg
     9361 aggagcagat gaagacggtg tcgagctttc ttcggatgaa gaagaaggaa ccgttgttga
     9421 agacgctggc tcgcttgttt ctgctgtcgt gctttctttt gaggactcag cagttgattc
     9481 gctttgacta gtagagctag agctttgagt cgttgtctct gttgttgagc ttccaggagt
     9541 ctggacatag ctggaagatg gaatagttgt tgatggtgta attgcattcg atctagctgt
     9601 atattgatct ttgtagtaca gttcaccgcc cacacgaatt aatccgcttg gcatctccca
     9661 gtctgtattt gtcacgttag ctgaaacata ctgcataagc tcgcgataaa catcagaggc
     9721 tacgtgtgac gattctgaag tgacaggtgt cattttttta ttgtaacctg tccacacgga
     9781 aatcgaataa tttggcgtat agcccgcaaa taggatatct ggatacaccc cagaagaaat
     9841 accaagtttt gcatactcgt catctgtgta attggatgtt ccggtcttac cggcttgata
     9901 taacccagcg atttgcgcat tcgtaccagt tccttcagtg atcgtatctt ttaaaatgtc
     9961 tgtgatcata taagctgttt ctggagacat ggctgttttt ccatctggct cataagtttc
    10021 ttctgttccg tcttggaaga cgattttatt aacatattga ggtttgtaat aagtccctcc
    10081 attggcgaaa gccgcatagg ctgctgccat ttttaaggaa gaagctccgt attttgtccc
    10141 atcttgttct tccgtattac tagagatcgc attcgattga tggatcgtac tgtattcgat
    10201 cccaagattt tttaagaaag aagccacttt atctgaaccg acttcattga ataatttgac
    10261 tgctggaaca ttacgggata agtaaagtgc ttggcgtaaa gtaatggtgc ccatatattg
    10321 attatcccag tttcctacag gagtcgaagt cccttcatag ttatacggtg cgtcagtaat
    10381 agtttttcca gtagaatatt tcaaatattc aaaagctggt ccgtaatctg tgacaggttt
    10441 catcgtagaa ccaaaatcac gggaagtatt cactgctaag ttgttgccta aagttacgtc
    10501 ttctgcgatg tgacgtccgc caatctgggc ttttactttc ccggtattgg tgtcgataag
    10561 ggtggaggca acttgcatct cgtcgtctgg gtaagagaca tactgatccg tgttgacgat
    10621 atcatatagt ttcttttggg cgtccagatc caaattcgta taaatctcta aaccgtctgt
    10681 gtagacattc ttatctgttt tttcttgtac ttcattgatg acttctttga cataattatc
    10741 gacgatctta gtattgtcat cggattgagt tagttcttgc agaccatccg ttaccggtac
    10801 attaacagct tgatcatatt ctgtttgaga gattttttcg ttttgaagca tcgtatacaa
    10861 aacagtatct cgtcttttct tcgcctgatc tggataaaca taaggatcat aggcggaagg
    10921 ggcttgaggc atcccagcaa gcaatgctgt ttgcggtaaa gaaagttctg ataatttctt
    10981 accaaagtac atctcagaag ctgtctccat cccgtacaag ccgtttgaca tatacacttt
    11041 atttacgtag taggtcaaga tctcttgttt cgattttttt tgttccaatc ttacagccat
    11101 ccacgcttct tgggccttgc gtttcagagt ctgatcctcg gcactggtgg agaagaagga
    11161 aagtttgatc aattgctgtg tcaaagtact tccgccttgc agtccgccag aggtaaagtt
    11221 agagagggca gaaccgatga tccgaatagg gtcaaccccg atgtgtttat aaaaacggcg
    11281 atcttctacc gacacgatcg catcttctaa tgttttcggt aattcattcg cagaaatttt
    11341 ttcacgcttt tctgcgccta aatcttcgaa tagttcgcca tcttgtgtat atagtttgga
    11401 agatacggta gcgtctaatt ttttatccgt caattcgggc gcatcttttg cgtaatacca
    11461 gaaaagtcct acacctgcta aaaagaggat acagaaaaat gagagtattc ctaaaaggat
    11521 cttgataaat aatccttttt tatgtgttcc agaggacttt ccagaacctt tgccagaatt
    11581 cttcttcaca ctctttttag gagtaggctg tttctgtcgt ctagagcttc tagtttgttc
    11641 atttgccatt cttgctttct ccttcaatag ataatgttga taaatagaag tcaaccgcgt
    11701 ccaaataagg aatccgcgga gaaataccag ttttgatctc tattcctagt tcttcgatca
    11761 aagataaagg tagtgatttg cgtccttttt ccttttgggc gtcccagtaa gcaatcaaat
    11821 gaacactatt caaataaaaa cagcgcttca aagacgaaaa ccataacaag acaaagcaga
    11881 ccccattttg ttcgaggcat gctttcatat gttcgatttg atgggcatgg aagtttttaa
    11941 agggaaaaga tgttttgttc ttggtttctt ttgcttcaaa gtccaagtaa aagcctcgat
    12001 agacgccatt atagtctgta gttgaggctt gggtaaagta ggcttccttg atcacagcag
    12061 cacttctctt aggatagtct actttcacga tttggatagg ggtaggcttt ttatggataa
    12121 ccgccaaccc gcgggaaaga taatatttat tactttcatt gattgcttct tcaaagcgca
    12181 tcccccgatt gccgaattca gtgatctgat ttcttttttc ttgaattttt tcgacgggag
    12241 aggcattctt ataataaggt tggccatttg gatagcgcaa taccatcttt aatcacactc
    12301 ctaggccaca ttatagcaaa aaagcggata gaaagaaaag gaatctgaga tggataagtc
    12361 aaaagtaatc tatgtgtctg ggtatcgaag tttcgaactc ggtgttttta aagaaaatga
    12421 tcctaaaatc caagttgtta aaaatgtttt aaaaaaagaa ctccatcagt tagcagaaga
    12481 agggctggaa tgggtacttg tcagtgggaa tttgggcgtc gaactatggg ctgtgcaaat
    12541 agtagcggaa ttgaaagaag aatatccgga actatctctt ggtattttgt atcctttttc
    12601 tgattttggt aataactgga atgaagggaa ccaagaaaaa aaacaattag cagaacaatt
    12661 agcagattat gtcgaagctg ttagccatca accctaccaa tcacctagtc agctaaagaa
    12721 tcacactcgt tttatacttg agcatacagt gggctgtctg ctgatctatg atgaagaatt
    12781 ccctggaaaa acgaagtatt tttttgaaga tgcacagaat taccaagcag atcatcccta
    12841 cgaaattcgg ctgatcagta tggacgatct tcaaaatttt agtgaataat cgatattgtg
    12901 tttgatttat caactttttt cctatacaat gaaaaaggta gaaatgttat tacgtaaatg
    12961 aaaactagag gtgtaaatat ggcgaatttg gtttatagtc ctaaagacat tttacaacaa
    13021 gaattcaaaa caaaaatgcg cggctatgat cccgttgaag ttgatgaatt cttagacaat
    13081 atcatcaaag attatgaaac ttacagcaaa gaactccttg ctttacaaga agaaaacgat
    13141 cgattgagtg caaaagtagc tcaattatct aaaactcaag gagcagctca aacacgcgtg
    13201 caacaaacag aggcaccaaa gagcgcagca gtgaccaatt ttgatatctt aaaacgcttg
    13261 tcaaatcttg aacgtgaagt atttggtaaa aagcttgatc aacaagcaag tgcagtcaaa
    13321 ccagcacaac ctaatccaaa taactacaca aatgcagaca caagcttaga tgataatgaa
    13381 aaaacacgtc aattttaatt tttgattaat gaatttgcgg ttttcgggta atcgcggtct
    13441 gacttgatca ggctgaggaa agtccatgct cgcacaggct gtgatgcctg tagtgttcgt
    13501 gcttagcgaa accataagct aaggtactct ttggagtaac ggcaggaaaa caagctaagg
    13561 cttcggctat gcttaagtat ccttgaaagt gccacagtga cgaagcggct ggggaaaccc
    13621 atccggtgga acgcggtaaa cccctcgagc gagcaaccca aacaatggta ggggcgcttt
    13681 ttgtctggaa gaagaacagg acaaaaaggc agtataactg cagatagatg gttaccgctt
    13741 tgttttttct ccctggaaaa gcaaagtaca gaacatggct tatagaaaac cgcaaacatc
    13801 agggaattag gtcgtgacaa aagtaatgcg ttataagaaa caagaaaaac atttgaaagc
    13861 tatttttcaa tacttcagat gaatcgttct tattacaaaa caaacttttg tatcaccggt
    13921 tattcggaat ttgagtaaaa gtgtggggta ggactgatgt cccacctcct ttttttataa
    13981 ataaggagat tgtgtatgga aaaaaacagg aagttcaacc tcgtcgcaac tgcggcaagc
    14041 gggctagaag cactggttgg taaagaatta agagatcttg gaatcgaatg ccaagttgag
    14101 aacggacgtg cacgttttga aggaacaatg gaaacgatcg ctacagctaa tttatggtta
    14161 cgtacagcag atcgagtaaa aatcgtggtt ggggaattcg atgcgtatac gtttgatgaa
    14221 ttgtttgaaa acgtaaaagc attgccttgg gaagattttc ttccactaga tgcagctttt
    14281 cctgtagctg gaaaatcgat caagtcgaaa ctatatagca cacctgattg ccaagcgatc
    14341 acaaaaaaag caatcgttga acgtctccgt acctattatc accgtccagc ttctgtacca
    14401 ctgacggaaa ctggcgcaca ttttcagttg gaagtagctt tgctgaaaga ccatgtgatg
    14461 gtaactctgg atacgacagg accaagttta ttcaaacgtg gttatcgctt agaaaaaggt
    14521 ggagcaccat tgaaagaaaa catggcagca gcacttatta tgttgacaaa ttggcgaaaa
    14581 gaccgtccat tttatgatcc tgtatgtggt tcaggtacgc tttgtattga agcagcctta
    14641 ataggccata atatcgcacc aggattcaat cgtgagtttg cttgcgaatc ttgggattgg
    14701 ttcagtcaag aaatcatgga aaatgttcga tcagcagccg aagaaaaagc agattatgat
    14761 attgaattag atattactgg ttcagatatc aatggacgga tgattgaaat tgccaaagcc
    14821 aatgcagaag aaatcggatt aggctcttcg attaccttta agcaacaagc agtcaaagac
    14881 ttcaaaacgg ataaagaata cggggtcatc gtggctaatc cgccttacgg agaacgtcta
    14941 ggagaagaag aaactgttcg gaaattatat aaagaaatgg gcgatgtatt ccgtccatta
    15001 aaaacatgga gtaaatatat cttgactagc gacttagcgt ttgaggaatt ttacggacaa
    15061 aaagcaacca aaaaaagaaa attgtacaat ggtgcattgc gtacggatct attccagtat
    15121 tggggaactc gtccgcctag aaaaaaagag aaagacgaat aatcttacta attgattcat
    15181 tcaattggat gtttggagga atagggaatg aaagaaaaag agtttttaca agaagtaaaa
    15241 gaaatcaatc ttctacaaca agctttagga atcctcgatt gggatacaca aacaggtatg
    15301 cctgaaaaag ctagtgcata ccgaagtgaa gtagacagct atctttacag catttatttt
    15361 tcaaaaaaaa tcggtccaaa aatcaaagaa gccattcgct atttttctga acatccggaa
    15421 gaattgtcgg aagttggaac tgccgttttt gccaaagtaa aagaagagta tgatttggaa
    15481 catcgcgtac cggaagatct tatgagaaaa tatacagctg ccgtttcttc agcacacgga
    15541 caatggcaaa aagctagaga aacacaacaa ttttctgatt ttcaacacgc attgaatcaa
    15601 aatattgaat taacaaaaca gttgatacct tactggagaa aagatgaaaa gacgaattat
    15661 gatgttttgc tgaatcaata cgaacccggg atgactgtcg aaatccttga taaggtattt
    15721 gatcagctta aagaaggaat tctttcgatc cgccgtacgc tccaagaaaa agggactgaa
    15781 cctgaaacag actttttaaa tcggagaatg acgagaaaac aacagaagag atttgtagtg
    15841 aaagtaatcg aacaacttgg ttatgatttt agtcgtggtc gtttagatga cactgtccac
    15901 ccatttatga ctggaattaa tccgaatgat gcacgaatca cgacacgatg gaacgaaaca
    15961 gatttcaaaa tggctgtttt tggagtgatc cacgaggctg gtcatggtat gtatgaacaa
    16021 gacatcgatg ataaatatgc gtatacaccg gtttatgaag gtacatcaat gggtatccat
    16081 gaatcacaat cgttgtttaa cgagatcatt attggaagta gtcgcagctt ctggaaaaag
    16141 caatatcctt tctttcaaga atgtgcagaa ggaacattcg atgatattcc ttttgacaaa
    16201 ttttatcgtt cattgaacca tacaaaatca agtttggttc gtatcgaggc agacagtttg
    16261 acttaccctc tccatatcat cattcgttat gaaatcgaaa aaatgatttt caatgaaggg
    16321 gtagatgttg ctgaactacc tgaaatatgg aatcaaaaat atgaagagta tctgggaata
    16381 cgaccaacaa atgatgtgga aggcatccta caagacgttc attggtcagg tgcaagcttt
    16441 ggttattttc cctcttatgc attagggtac atgtatgcgg cacaattact tcattctttg
    16501 cagcaagaaa tagatgtgga aaatgttcta gcgtcagacg attattctcc aatcaaaaac
    16561 tggatgtcag agcatatcca tcaatatggt gcatctagaa aaccaaatca attaatcatg
    16621 gatgcaacac atgaaccgct taatccgcaa tacctgatcg actatatgaa agacctgtat
    16681 tttaatgtat atcaggtaaa ataaaataca atttacaaag atagctgaaa ttcatctaat
    16741 ctatagatgt tttcagctat ttacttaaga aagaagtgga acgaatggat aaattacaag
    16801 tgatcgctga ttatagtatg gaccaattag cgcatgatca aacaggacat gggagcgatc
    16861 ataccaaaag agttgtcaag ttagctgaaa aaattttgga gacggaaccg caggcagacc
    16921 gctttgtgac gcttgcagca gcttacctac atgatacgat tgatgataaa gtcgttaaaa
    16981 atgagaacga ggcaaagcaa cagcttcgtg tattccttcg ctctttgcca atagtagagg
    17041 aacagatctc gatgattttt tccattatcg aaaatatgtc cttttctaaa aatctctctg
    17101 aagcggccga actatctctg gaaggtaaga tcgttcaaga cgctgatcgt atcgaagcat
    17161 taggagcaat cggcattttg cgtactgctt atttcggcgg tggacatggg cacccgattt
    17221 ttgatcctga actgtatccg caaacattca aggacaaaga aaattaccga aaaggcacga
    17281 cagtgatcaa tcatttttat gaaaaactgt tcttgctgtc tgataaaatg aatactgatt
    17341 acggatatga agaagccaaa cgaagagaaa ccttcatgcg tgaattctta gaagaatttt
    17401 ttctggaatg gtctattgac gatgaaaatt ttactccaga caattggatc aaaaataaca
    17461 aaaaatgatg gaggttgtga cagaagtggt cagctccaag atatttcgga tcattttccg
    17521 taaaagttac ttctggaaca ctgtttacca agaggtcgtg agcctgccgt tcagctccga
    17581 gtcacaagga acaatttcaa aaaatagctt ctcgtgtttg atgaatattg taacttgtga
    17641 ttcggaattg gcaggagaac accgtttatt cggaagaata ggactgtgac aagacttttg
    17701 tcacagtcct tttttcgaat tcaacaagta aaacttttaa gaaatattca gagagtaaaa
    17761 ttaaaaattg ctgataaacg aagatggaaa ttttatgtat ttttattggt ctatgcaata
    17821 aataaattaa atattcagaa tacaattgat tttaacgaaa gggcttctat caatggttgt
    17881 gttgtattta tctgcccagg tagagtaaaa tagatcatta tctaaaaggt aattgttcat
    17941 actatataag tcatttgaaa gtaaaaagat actgtaaata aaaaatgtgg ttaaataatt
    18001 ctcataatca gtgtaagcgt tatcaaaaat atagcatact tgctttgtag atgaatgaca
    18061 cgatatatgt ttggtatgtt ctgcaagaca gatgaatatg gaggtggaga caatgtcttc
    18121 caaagaacta acaatgtatt tagagaaaga attggatcaa ctgaaagaaa aggggttata
    18181 caatacgatc gacatactag aaagtgaaaa tggtgcttgt atcatcgtag acggaaaaaa
    18241 gatgatcaat ctagcatcca acaattatct tggatttgcc aatcgcgaag aattgaaaaa
    18301 agcatgtatt gaagcaaccg aaacttatgg tgtaggagca ggagcagtcc gaacgatcaa
    18361 tggttcgctg aaaatccatc agcaattaga agaaaaaatc gcagaattca aagggacaga
    18421 agcagcaatc gcctttcaat ctggattcaa ctgcaatatg ggcgctatct ctgcagtaat
    18481 gacaaaagaa gatgctatct tatcggatga attaaaccat gcatctatta ttgacggttg
    18541 ccgcttatcc ggagcaaaaa tcatccgaat taaacatcaa gatatgaaag accttgagaa
    18601 aaaagcaaag gaagcgatag aaagtaagaa atataaaaaa atcatgtata tcacagatgg
    18661 tgttttctcc atggatggag acattgcacg attgccggaa attattccga ttgttgaaaa
    18721 atatggactg atcacctacg tcgatgatgc gcacggctca ggcgtaactg gaaaaggtgc
    18781 aggaaccgtc aagcattttg gattaagcga caaaatcgat atgcaaatgg gcacgttatc
    18841 gaaagctata ggtgttgttg ggggttatgt agctggatcg aaaacactaa tcgactggtt
    18901 gaaagctaga agtcggccat tcctattttc tacttcgcta actccaggtg cagctgcagc
    18961 tgcattggct tcgattactt tgatgcaaga acatccggaa cttgtcgaaa aagtttggga
    19021 aaatgctaat tattttaaag aagaattgaa aaaagtaggc tataacatcg gtatgtctga
    19081 aacacctatt actccagtca ttttgggaga cgaaaaagtg actcagactt tctctaagaa
    19141 gctgatcgaa catgggattt atgctaaacc aatcgtttat ccaactgtgc ctcttgggac
    19201 aggcaggatc agaaatatgc cgactgcgga acatacgagg gaaatgcttg atgaagcagt
    19261 agcagtttat caaaaaatag gaaaagaaat ggaaattatt taactaaatt tagttttttc
    19321 gtctatttaa aattagagaa catgttcacg catatattgt taatcatctg aagatagtag
    19381 taaaaaagat cagggaggat catcatgaaa aaagtattgg tgacaggatg tttaggacaa
    19441 attggttcag agttgatcac acggctacgt caagaactag gcagtggaaa tgtcattgcg
    19501 acagatatac gcatgcctga agtcattgag aaaaacgata tctttgagat cctagatgta
    19561 atggattacg aaaaaatgcg cagcatagca gaacaatatc aagtggacac attgattcat
    19621 ttggctgctc ttttgtcagc tgttgcagaa gcaaaaccac aattagcctg gaatttgaac
    19681 gtgactgggc tggtcaatgc attggaagtc gctagagaat tccagctgaa attttttacg
    19741 ccaagttcaa tcggcgcgtt tggtccaaat actccaaaag atcatacccc acaagatact
    19801 cttcagcgtc ctacaaccat gtatggggta acgaaggtag ctggagaact actatgtgat
    19861 tattattatg tgaaatatgg cgtagatact cgtggtgtcc gtttccctgg attgatttct
    19921 tatgcaacct tgccaggagg cggtacgaca gactacgcag tcgatattta ttattcagca
    19981 atcaaagaag gaaagtacac tagtttcatt gatcaaggta catcaatgga tatgatgtat
    20041 atgccagatg cgatcgatgc cattataaaa ctcatgaatg cagatcctga tcgattggtt
    20101 catcgaaatg ccttcaatat atcggcgatg tcttttgacc cggaagagat caaagcatct
    20161 attcaaaaaa tcataccaga ttttgaaatg gattatgatg tggatcctgt acgtcagtca
    20221 atagcagaat cttggccaaa ttcactagat gtttcttgtg cgcaagagga atggggcttt
    20281 tcgccgaaat acgacttaga tgtgatgaca aaggatatgt tggaaaaact gaaagaaaaa
    20341 ttggtagaga cggtataaaa caagaaccac atccaaaaag ttttttatac ttttgggatt
    20401 ggctatggta tgaaagggga caagggatgg aagaatatca agccacgcca gtaaaagaag
    20461 taaaaataga aaatgaatta aaacgtacga tgggattttt tactgcttta tcgactgtta
    20521 tgggcacagt gatcggtgca ggggtatttt ttaaagccgc aagcgtagca gaagttacag
    20581 gatccgccag tttgcatatg ttttcttggt ttctcggtgg tatgatttct gtctgtgcag
    20641 gactaacagg agctgaactg gcagctgcta ttccagaaac aggagggatg attaaatata
    20701 tcgaacggat ttacggaaat acagcagctt ttttattggg ctgggcgcaa gtcgtgattt
    20761 attttccagc aaatgtagca gccttgtcga tcattttcgg tacacagttc gtcaatctat
    20821 ttggtctttc ccagtcaatg attgttcccg tagctgttac agctgctgta tcgatcctgt
    20881 tgatcaattt tttaggttct aaagctggag gggcttttca gtcgattacg cttgtctgca
    20941 agcttattcc tttgtttgtg atcgtcattt tcggtttgtt ccgacaagaa ggagtagact
    21001 tccaactgtt tccgatccaa gcaggagaaa atctttcatt tttctcagcc ttgggagcgg
    21061 gcttgctagc aacgatgttc gcatacgacg gttggataca cgtaggaaat atttcgggag
    21121 aattgaaaaa gccggcgaaa gatttgccaa aagcaatttc tttaggaatc atcggaatca
    21181 tgatcgttta tttattagta aatgcggtgt tcttaagaac cgcatctatc gacggagtcg
    21241 caggaaacag caatgcggca agtgacgttg caaaaatgat ttttggcggc ttcggtggaa
    21301 gactggtcac agttggtatc ttgatttctg tttatggaac catcaatggc tataccctta
    21361 ctggaatgcg tctcccttat gttatggcaa aagaaaacaa cctgcctttt agcaagctct
    21421 ttgctaaact tcatgataaa actaaagttc ctgtagccgc aggtatctta gagctagtca
    21481 tcgctattgg catgatgatg atcggtggtt ttgatacact aacggatatg ctgatctttg
    21541 tcatttggat tttttatacg atggtctttg ttggtgtcat tcttcttcgt aaaaaagaac
    21601 ctgatttgtt tcgaccatac aaagttccaa tgtatccgtt tattccacta gtagcaatca
    21661 ttggagggac ttttatcgta tcaagcacgc ttatcactca gaccttttta gcttcgatgg
    21721 ggatagtatt gacacttgct ggtatcccga tttatctcta tttaaaacgt agatagctaa
    21781 aacattcgaa ttttattaga actgcacttc tctgccaaac aaaatatttt atttaaatga
    21841 ggagtacgtg gaagaaatgt caaaagtact cgttaatttt gatcacgtaa atgtcgtttt
    21901 gtctacgatg aaatagcaaa gtaaaagaca gaaatcgggc tcaaccgatt tctgtctttt
    21961 actttgattt gcgtaactga actattcggc gtacgccgcg ataaatattt aataaaacca
    22021 agcaaccaga aatgaaaatg ggaagccaaa tcagatagac agggtagcca agcactttag
    22081 acaaagcatg tggagtcatt ttatccattt caagaagtgc ttgctgccaa gtctgaagat
    22141 tgaagactag catgaaaccc gaaataatca ggagaataaa tcctaaataa tgaattgtag
    22201 ttctttttct tacataagcg atcgtagcat aaaggaacag taaaaaaata ggtacgccaa
    22261 aaacaaagta catattcagc atctcgacac cccctttgtg tttatcttac tttactttga
    22321 aagaaatgag aaataatagc ctcgttactt gcttgaaaca gcaaaggact gctaagataa
    22381 gagagataca aagaatcaag gaggagtcat atggcaagtt atatcgaacc gattcgtttt
    22441 gcgctgattg tttttccatt tttagcctta gcgatctcat ctgttttttt tatttatgaa
    22501 tatcgaaagt atggaacatt tctagtaaca agggcagtta ttttgtattc tttcgttttt
    22561 tatttattgt gtgcgtattt tttggtgatc ttaccacttc cggcaaagga gacggttgcc
    22621 caaatgacag ggccaaagat ggagctgcat ttatttgctt catggcaaca tttcagagac
    22681 aacacggtat tggtcttgtc tgaacctagt acctacctgc cggcaatgaa gcagagtgta
    22741 tttttggaac cagcttttaa tgttttatta ctcataccat ttggcattta tttaagatat
    22801 tatttccggc tttcttttat gaaaacgatg attgctagtt tctgcctttc tctatttttt
    22861 gaattgacgc agctaagtgg actttatttt atctacccaa gaccataccg cttatttgat
    22921 gtgaatgatt tagtgacaaa tacattgggt ggaatcattg gttttgtcgt tacgccgtta
    22981 tttacattta tgcttcctac aagaagacga atggatgaac tttcttatga aaaaggaaag
    23041 actgtctcat tgactcgacg cttggtcgct tatttgatcg actggacatt tttatctctt
    23101 attaatttgg tagcggcgat tttctttaaa attgcgttcg attcaggggc agttacttct
    23161 catatctggt ggcttttatt agaagtaggg gtatacttta tgattgtacc gtttataacc
    23221 aatggatgga cacttggcaa aaaaattgtg cgtatccgtt tggtggaaga agaccgcgaa
    23281 cgaatttctt taaaagcatt gatgatccgc tacgggtatc tgtactttct tttttatggt
    23341 ttaagctggt tggggcagtt gcttcagcaa atcatgaatt cgacaacgaa tacggtgttg
    23401 cagatgagtg cagtattcat ttctctcggt gtcttgttac tacaaggtat ttttatttta
    23461 aatatcttgc tatcattttt gagaaaaaaa cggattctgt tttatgaaaa agctagtcac
    23521 acatatactg ttagcacgat tggccaaaca aaggatgatg attctcgaaa ttagctgagc
    23581 aaaaacgctt tgtctgtgtt ataatgccaa agtcgtgata atttaaagag aagaggtgca
    23641 cgaatgaata attttgatat attccgcttc aaaccgttta tcaatgaagc gttaaccgca
    23701 aagggcttca aacagcccac agaggtccag gaacgtttga ttcctttaat tgcaaaagga
    23761 aaaaatatca ttgggcaatc tcaaactggt acaggaaaaa cacatacgtt tttgttgcct
    23821 ttgtttgaaa aaatcaatgc agaaaaagag gaagtacaag ttgttattac agctccaagt
    23881 agggaactag ctgcacagat ctatgaagca gctacacaaa tcgctaaatt ttctacaccg
    23941 gagatccgtg tctcgaattt tgtcggcggt acagacaaac agcgtcaatt aaatcgtctg
    24001 catcaccaac agccacaggt tgtagtaggc acgcctggta gaatattaga catgatgaat
    24061 gaacaagcgc tgaagattca caccgcattt gcatttgttg tcgatgaagc ggatatgaca
    24121 ttggatatgg gttttttaaa tgaagtagac caaattgcaa gtcgattacc agaaaagctg
    24181 cagtttttag ttttttctgc cactattcca gaaaaacttc gtccattctt acgaaaatac
    24241 atggaaaatc caatcattga agaaatcaaa ccaaaagcag ttatttctga agacattgaa
    24301 aattggctga tttcaacaaa aggtaaagat gagaatcaaa tgatttatca actgctgaca
    24361 attggtcatc cttatttagc aatcgtattt gccaatacaa aacagcatgt ggatgaaatt
    24421 gccgattact tgaaaaacca aggcttgaaa gtagcaaaga ttcatggaga catcacccca
    24481 agagagagaa aacgagtgat gcgacaagta cagaatctgg agtatcaata tgttgtagcg
    24541 actgatttag ctgctagagg gatcgatatc gaaggtgtct ctcatgttat taatgcagaa
    24601 attccagaag atctagactt ctttatccat cgtgtcggac gtactggacg taatggctta
    24661 aaaggaacgg ccattacgtt atattcgcca aatgatgagc aagccattga tgcgatagaa
    24721 aaattgggcg tctcatttga accaaaagaa atcaaaaacg gggaaatcgt caaaacatac
    24781 gatcgtaata gacgtgccaa acgagaaaaa tcaaaagatg tattagatcc cacgctgatt
    24841 ggtcttgtga agaagaaaaa gaaaaagatc aagcctggtt ataagaaaaa aatcgattgg
    24901 gcaattgcag aaaaaaataa aaaagaacgc aaaatcgaac gcagacagca aagccgtact
    24961 gctcgtaaaa ataagaaaaa ttcacataaa taaaaaacaa gaggttgtga caaaaggcgt
    25021 gtcacaatct cttgttttta agctagactt tttttcattc cgatacaaag tacttcatct
    25081 tcaataaaag gttctgtgca agtatgatac ccttgttttt cataaaaatc tacagccgtc
    25141 atttcagcta ctacataact agtctgacaa ccttctgaaa ccgcccgttt ttcagcagct
    25201 tcaagcaact gaccgcctaa cccttttcct cggtattctt ttgctacgca aaatcgttcc
    25261 ggcttgaagc aagtaggtgt tttcttttca taacgcaaag tagctactgg tcttttttga
    25321 tcaagaaata gataataggt ttgttgcggg atatcttttc cgtcgaattc tagttctgca
    25381 ggaatccctt gttctaatac aaaaacttga tatctcaaaa agcagctagc tgcgcgtatc
    25441 cattcatccg ctccaactat ttttttcatc atattcctcc ttgtcatgaa tagcagagat
    25501 gtattgattc ctttattctt atcgtaccaa aaatcgtgga gtatgaccaa aaggaaatga
    25561 aaataaaaat tgagatattg acagtgatca atagaatgcg tatactaaat aagtacgaaa
    25621 aggatatgat ttgtttttta agactcacag aaaattcttt cttggctgaa aaaagaatag
    25681 tcactaatca aattgctccc tttttctatt ttggtagaaa taccgacgca gctcagcgtt
    25741 atcgagttta agaggtaatg attacacatc attgcaatca aggtggtacc gcgagttttc
    25801 gtccttggct gtgatggtgt ttttttgtat ttaatttata gaaagcaggt aatgacatga
    25861 aacaattaag tagtgcacaa gttcgacaaa tgtttcttga tttcttccaa tctaaagaac
    25921 atacgattga acctagtgcg tctttgatcc ccgtgaacga tccaacctta ttgtggatca
    25981 actctggtgt tgcaacattg aaaaaatatt ttgatggttc agttgtgcca gaaaatccaa
    26041 gaatcacaaa tgcccaaaaa tctattcgaa caaatgatat cgaaaatgtc ggtaaaacag
    26101 cacggcacca tacgatgttt gagatgctgg gtaatttttc gattggtgac tatttcaaaa
    26161 atgaagccat ccactgggca tgggaatttt tgactgatcc aaaatggatg gcattcgatc
    26221 cagaaaaact ttatgtaaca gtttatccaa aagatacaga agcaaaacgc atctggcatg
    26281 aagaagttgg cctgccacta gatcacatta ttgatgtaga agacaacttc tgggatatcg
    26341 gtgcaggccc atgtggtccg gatacggaaa ttttctatga ccgtggagaa gcttataacg
    26401 atttagcaga agacgatcct gaaaactatc caggaggaga aaatgaacgt tatttagaaa
    26461 tctggaactt agtattttca gaattcaacc ataagcctga taacacattt gaaccacttc
    26521 ctcataaaaa cattgatacg gggatgggat tggaacgcat ggtctcaatc gttcaagatg
    26581 cgtcaacgaa ctttgagaca gacttgttta tgcctattat ccacgccgta gaaaagctaa
    26641 gcaaacaagt aaaatatggt gaaaacccag taacagatat ttcttacaaa gtaatcgcag
    26701 atcatattcg cgccctttca tttgctattg gcgacggtgc attgccatcg aatgaaggga
    26761 gagggtatgt cttacgccgt ttgcttcgtc gtgctgtcat gcatgggaaa aaattaggta
    26821 ttgaacaagc attcttatat cgtttagtcc ctgttgttgg ggaaatcatg gtaagttatt
    26881 atcctgaagt acttcaacaa aaagaattta ttgaaaaagt tatccgtaca gaagaagaac
    26941 gtttcaatga aacaatcaat gaaggtttgg aaatcttaaa tcaagtgatc caagaagtaa
    27001 aaaacgaaaa cgggacgact ctagcaggaa aagacatctt caaactatac gacacatatg
    27061 gcttcccggt agaattaacg gaagaggtgg cagaagatga aggactgaaa gttgatcatg
    27121 ctggttttga aaaagaaatg gatgcacaac gcgaacgtgc tcgctctgcc cgcagtactg
    27181 aaaaatcaat gggggtacaa tctgctttat tgacagatat caaagtagaa agtaaattca
    27241 ttggatacac agaacaagaa tcagatagtc aattattggt catcgttaaa ggtgagtctc
    27301 ttttgaatga agtcgcagaa ggtgaagctc aaatgatctt tgatcaaaca cctttctatg
    27361 cagaaatggg tgggcaagta gcggatcaag gatggatcat gaatgaagta ggcgaaatcg
    27421 tagcagttgt tacagatgtt caaaaagcgc ctaatggtca atttatgcac accgtagaag
    27481 taaaagcacc aatgagtgaa ggacaaacct atcatctatt gatcgatcaa tcgatgcgca
    27541 atcggatcat caaaaaccat acagcaaccc atctactgca caaggcattg aaagaagtac
    27601 ttggcgagca tgcaaatcaa gctggttctt tagtcgctcc tggacattta cgattcgact
    27661 ttacccactt tggtcaaatc acttcagatg aattagctga aatggaaaga atcgtcaacg
    27721 aaaaaatctg ggaagctatc ccagttgaaa caattgaaac agatatcgat acagccaaaa
    27781 acatgggtgc aatggctttg tttggtgaaa aatacggaca tgacgttcga gtagtaaata
    27841 ttggcggctg gtcaatcgaa ctgtgcggag gcacacatgt agcaaataca gaaaacatcg
    27901 gaatcttcaa aatcgtttct gaatcaggaa ttggtgcagg cgtgcgacga atcgaggctg
    27961 taacaagtaa agaagcgtac gaactacttg aagaagaaga aaaacaacta aaacaagtag
    28021 caacaattgt taaatcacct caattgaaag aagttgtttc aaaagcggaa caattgcaac
    28081 agcaagtaag agagctacaa aaggaaaatg aacaattagc tagcaagtta gcgaatcaac
    28141 aagctggtga tgtattcaaa gatccagaaa cgatcaatgg aaaaacaatc attgcagcac
    28201 aagtaaaagt gaaagatatg aatcagctgc gtcaattagc tgaccaatgg aaacaaaaaa
    28261 atatttcaga tattcttgtt ttagcaaacg aacaagaagg aaaagtcagt ctgctagcgg
    28321 caatgacgaa agaatcaaat gaagctggac taaaagctgg cgacttgatt aaagcaatcg
    28381 caccgaaagt aggcggtggc ggtggtggac gtccagacat ggcacaagct ggcgggaaaa
    28441 atcctgctgg tattccagat gcacttaaag ctgcgaaaga atgggttgcg caacaatagg
    28501 gcgtttacgt ttgacagaaa aacaaaagtt caaacattga acgaaacatg attatggggg
    28561 cgaagacaaa caagtcttgc cctcatactt ttttcaattg gatggcgcat ctaatcaaat
    28621 ggtcggattc ggatggtctt tagttgacga aagtgacaga aatttttacg attagtataa
    28681 ataaaaaggg gtgaaaaaat gaatagtaga aataagacct ttcgactagt cttacgtgcg
    28741 atcttgttag caatcatcat cgtacaagcg atggttcctt ggctggggtt tattccatta
    28801 ggattcatta gtttaacaat tatccatatc acagtaatta ttgctgcagt agtattaggc
    28861 ccaaaagatg gcatggtgat tggcttgttt tggggaatcg ctacaattgt tcgtgcctat
    28921 gccatgccaa caacgccatt tgatacatta gtgttcacga atccgattat ctcggtagtt
    28981 cccagagtac ttgttggctt agtagcaggc ttggttttcc actggattta tcaaaaaaat
    29041 aaatcaataa cgatcagctc agcctttgca ggggtactgg gttcattggt caatacagtc
    29101 ttagtgttag gattcatggg attattttat acaggtgcaa cggcagatgc ctatggtgta
    29161 gactctgctc ttttatttaa aaccttagca ggggttgcag caatcaatgg gataccagaa
    29221 gcaataggtg cgggaatcat aacaccatta ctagcaaaag cgttatttgc agcaacaccg
    29281 ttgaaaccag aataatgacc atcttttaat agtaatagga cgcacgatag atagaaaaag
    29341 gaagagagga gaggaaaaca atcgtcctct ccatcttttt acctgagcaa caagcaaact
    29401 agaaggggta aaaaacttgg ctaagaaaca agaagaaaaa aagaaacaaa taccgcaaca
    29461 gcggacaaaa aaaggagtac tagcgggtat cttaggattg gttacgaatc tgatcttgtt
    29521 tgtctctaag ctaatgatcg ggcttttttc aggaagtgtc tccattatgg ctgatgcagt
    29581 gaacagtcta tcagatactg cttcatccat attgactttg atcggattta aaattgctgc
    29641 aaagccagca gatcaggaac atccttatgg acacgaacgc ttcgaatata tcagtgggtt
    29701 atttgtttcg atcatcatta cttatgtagg atttcaattt ttagagtctt ctgctgaaaa
    29761 aatcatccat ccagaaaatg tctctttaac acccatcgtc ttttttgtcc taatcatttc
    29821 catctttttg aaatttgcac aaggcaaaat gtatcaggtt attgcgcaat ccattgattc
    29881 tgaaacattg agagctacag caacagatag ttataatgat gtctttacta cactggctgt
    29941 attgctttca gcagcaatcg aatgggtaac tggatggcgt attgatggat atataggttt
    30001 tgctttagca ttatatatcc tttatagtgg attgacgatg cttcgaaatt ttgtatacga
    30061 actattagga agtcgcccaa cgccagcaga gattgaagaa atggaagagc atttaaatgc
    30121 ttgcgatgat atacttggct atcatgattt attggtgcat aactatggac ccaataaacg
    30181 ctttgcatca gtccacatcg aagtagatga atcaatgaat ttgaatgtgg ctcataagat
    30241 tattgatctg atagaaaaag actttaaaaa gtctttggat gtggaacttg tctgtcactt
    30301 ggatccaatg cctgttgata acgaaaaata ctataatatc ttgcggcagt taaagcaaat
    30361 tcttcttgaa acaggtacag ggcttaatat tcatgatttt agagtaattc atcaaggaaa
    30421 aacgctgcaa tttgatgtag tggtccctga gaaattccag tttgttgata cagaactaga
    30481 aagaatctta cgtagtcaaa tagaagaaaa aatcggagat taccaattgg aaattacgtt
    30541 tgatcacaat tatcttttat attaaatgag aaactataaa aagactcctt aaagttttta
    30601 atttaaagag tctttttttc ttttaattgt ttatggagag cctgacgtgc aagattatct
    30661 gctcctttat ttttgttttc gggcaaccat tgcaggatca ataaagaaaa ttcggataga
    30721 agttcttgga ttctttgaag gtagggaagg aagagctcgt tcttcgttgc gtttttgtcg
    30781 accgtagaaa ctagtgtttt gctgtctgaa aaacagaaaa tcgtttcatt ctgtaagtcg
    30841 tttttcttta gaaattctaa agtttttaaa aagacttcga actctgcttg atggtttgtc
    30901 cctatagaaa gcgggataga tagctgttct tgtttacctt gatagacaat caagattcca
    30961 cctccactag gaccagggtt gccttttgta gaggcatcaa tgtatacttt taacataaaa
    31021 agagattctc ctttttgttc aaactaatgt tatggtaaga ttatatcatt actgaatcgg
    31081 tgagaggtta gagaatgaaa aaaaatattc gatggcagcc tgaactggca catacgatca
    31141 tctattggtc attgaccttg atcattctgt tttttagtct gattctttct ttagaaaaca
    31201 caggtcctta ttggaaaagc aattttgttt taggtatttt tcttgttttt ctatttctag
    31261 gtttgcggcg ttcttttatt ttaaaatcaa actctgtgat tatacgttat gctgcttttt
    31321 ggaaagaccg agaaatatct gtcggacaga ttcgatcttt gacgccaact aatactgggg
    31381 tgcaaatgat gttgcaagat gagaaagccc catctgtttt catgatgcga aaaaaagatc
    31441 aagtagtcct ttttgatcat tttgaaaaaa acggacccaa atcagaatca attccttatc
    31501 cttatacgaa aaaaagaaaa agctaatttt aaaaatcaga acctaaaaaa acgaattttt
    31561 acaggaaaag aaaagagtga gacgtacggt tcatcccgtt tagcgtctca ctctatttgt
    31621 ttatctattc atgcatacta gtatcggtag tctgaacgtt gcctttcttg acatgggcag
    31681 cttgtgttcc tcgattccct tcgatgatct caaattcgac cacttgattt tcttccaaag
    31741 ttttgaatcc ctcttcttca atcgcagtaa aatgtacaaa aatttcttct gtgtcatcat
    31801 aactgataaa gccgtatcct tttttgttgt caaaccattt tacaattcct gtggtcaaag
    31861 cactcacgac ctttctaaag tctgatcata gccttcatta taaagagtat ttataagtac
    31921 gtcaaataaa ttaaaaacct gtaattttat gttttttttc tgaataaaaa aaggtataat
    31981 tggcatatct taacaaagaa gatattttgt tgaataaagt tcgtgaaaag gggtaatcaa
    32041 atgaagaatg atctgcaaat ttcacaagaa acagagctag aaccgattgt tgaagtggct
    32101 agtaaattag atcttaagga agacgatttg gaactgtatg ggaaatataa ggcgaaaatc
    32161 aatttttctg gaatcaatcg atcaaaggat aacgctgagg ggcatttgat cttagttact
    32221 tccatcaatc caacaccagc tggcgaagga aagtcaacga tcactgtagg gttaggagac
    32281 gcgctcaata aaatcaataa aaaatctgtt attgcattgc gagaaccctc acttggtcct
    32341 gtgatgggaa tcaaaggtgg tgctgcaggc ggaggatatg cacaggtatt gcctatggaa
    32401 gatatcaact tgcattttac tggtgacatg catgctatca caacagctaa taatgcatta
    32461 tctgctcttt tagataatca tattcatcaa ggaaatgaat tgaacatcga tgcccgccga
    32521 gtgatttgga aacgggtagt cgatctcaat gatcgtgaac tgcgtaaagt aattgttggc
    32581 ttgggtgggc caatccaagg tgttccaaga gaagatgggt ttgatatcac agttgccagc
    32641 gaaatcatgg ctatcttgtg tcttgcggca gaccttgaag atttaaaggc tcgtcttgca
    32701 aggatcgttg tcggctatac atttgaccgt cagcctgtga ctgctggaga cttgaaagca
    32761 gaaggcgctc tggcattact gctgaaagat gcaatcaagc cgaatcttgt acaaacaatt
    32821 tacggaacac cagcttttgt ccacggggga ccgtttgcca atatcgctca tggctgcaat
    32881 agtattttag ctaccaagac agcattgaga ttagcagatt acgttgtcac agaggcagga
    32941 tttggtgcag atcttggcgg agagaaattt ttagatatca aagtacctaa cttgaaaaaa
    33001 gcgccggatg ctgtggtgat tgtcgccact gtccgtgcat tgaaaatgca tggcggaatg
    33061 aaaaaagatg aacttaaaaa tgagaatctt gatgctttga aagtaggttt tgcaaattta
    33121 aagcgccata tacgtaatat ggaacaatat cagctacctg tgatcgtcgc aatcaatgaa
    33181 ttcgtaacag atacagacaa tgaactcaca ctgttggagc acttgtgtga aaatcagggg
    33241 attcttgcca agagagcgag tgtatgggca gatggagcag aaggcggcgt tgatttagca
    33301 aaagctgtag tacgattgat tgatagaaaa gaagctaatt acaagccatt ataccgccta
    33361 gaagaaacga tacaagaaaa gacagaaaca atcgtcaaga aaatttacgg aggaaatggt
    33421 gttgttttca gcaaaaaagc gcaaaaacaa atagaagagt ttacgaagaa tggatgggac
    33481 aaactgccga tttgtatggc aaaaacacag tattcatttt ctgatgatcc ttcactgcta
    33541 ggtgcaccgg aagatttcac catcacgatc cgcgaaatca tcccaaaatt aggggcagga
    33601 tttttagtag ccttgactgg agatgttatg acgatgcctg gtttgcctaa aaaacctgct
    33661 gcattgaata tggacgtgac aaatgacgga gaagtgttgg gattgtttta agcttgatta
    33721 taatctacca tcgaaggagc tgtattttga ctacagcttc tttttttaga cgatagggaa
    33781 ttaattttgt ttacactagg atcattcttt ttctttattg tattttgagc tatactaaag
    33841 cataatagga gggtatgatg aaaacgacat ttataagaaa aaccggtttt tacggtatgg
    33901 gtagctcgat tcagctaaga atcaacaatg aaaaacgcag tgttctcagt catgaacaaa
    33961 agataacgct tgatctggaa gtgcccttta cgatgcaggt caccttttat tggctaaaaa
    34021 gccccgttta tacagtgaaa gaagcaaagc ctgcttatgt gatcacaatg aattacttga
    34081 ttcttcaaat ctatccgttt ttatttctag caactgggtt gggggccgtt ttcctacaaa
    34141 atttattttt cagttttttt gcagttattg tgttgattgc gttctttttc tatataaaaa
    34201 accgggcata tttgatcaag gaggaaaatt atggcaaact ctgatctttt tttaatcagt
    34261 ttcaatcgaa tcgaaaaatg gatgagagac gagatgggaa atgcacgaaa tatgggattt
    34321 accgaacttg tcagacgcct agctcaaaga aaacaattaa tgatcagaaa atacgaagat
    34381 gatcttttac agcttgctca gttaaggaat gcgatcgtcc atgatcggat cgcagtcgat
    34441 tttgtcattg cagagccaaa tgattggaca gtcaagcgaa tccagctgat cgaacaagaa
    34501 ctgattcagc ctgaaaccgt gctgcctcga tttgcaaaac gtgtaacagg ttttgaacaa
    34561 gatcttccgt tacttgaact gttaaagata gtagcagaaa aaaggtattc acaatttccg
    34621 ttatacaata aaggaaaatt tgtagcattg attactttac gtaatatcgg gttttggcta
    34681 gcaaaagaaa gccaaaaagg tccggttgat ttaacaaata aacgagcgtt ggatttgatc
    34741 atccaaaacg gaaagtacac aaattatcat tttgttccag ctaaaacaca tatttacgag
    34801 gttgaagcga tgtttcgtga gcaagggact ttggaagccg tacttatcac taaagatggg
    34861 aatcccgatg gtaatctgct cgggatcgta cgacctcgtg atatttataa acaaatagaa
    34921 aaggattgat tttttgttaa ttatttattg gatattcagc gctttgctag taggagtgga
    34981 tcagttggtc aaatggtgga tcactgataa tctagcgctt ggagagacga aaaatcttat
    35041 accaggtatt ttgtcactga atcatattcg aaacactgga gccgcatgga gtatgctaga
    35101 agggaagatg tggttcttta ctatagtgac actcattgca gtcgttgtga ttctcacatt
    35161 gatgattaaa aatcgtgaaa aaggtaatcg ctggttcatg attggattga gtttgattct
    35221 agctggtgcg attggcaatt ttatcgaccg tattcgtctt ggctatgtag tagatatgtt
    35281 ccagacagat tttatgagct ttccgatttt taacgtagca gatgtgacac ttgtatgtgg
    35341 agtgatttgt atgttaattt atattatttt agatgaaaag gatcaaagaa aaaaatgaca
    35401 gaacttaaaa cgacgattca ccatgaatct ggtaggatcg ataaagtatt gactaattta
    35461 ttcaccgatt acagtcgttc gcaaattcag ctgtggctga aaaatggagc ggtttctgtc
    35521 aatggacagc cagtcaaagc aaattacaaa gtaaaacaag gagacgagat tactgtcttg
    35581 atccccgaac cagaaacatt agatgtggtc ccagaaaata tcccgttgac gatcgtttac
    35641 gaagatgaag atgtagcggt gataaacaaa cctcaaggaa tggtcgttca tccttcagca
    35701 ggtcatacgc atggcacaat ggtcaatgcg ctgatgtacc atatcaagga tctttctacg
    35761 atcaacggcg ttattcgtcc aggtattgtt caccgaatcg acaaagatac ttccggactg
    35821 ctaatggttg ccaaaaatga ccaggcacac gaatcattag ctcagcaatt aaaagataag
    35881 acctctttgc gcaaatatgt tgctttagtc catggagaga ttcctcacga aaaaggaacc
    35941 atcaatgcgc caatcggccg ttcgaaggaa aaccggaaaa tgcaggcgat aagagaagat
    36001 gggaagtcgg ctgtcacaca ttttactgta ttggaacgtt tcgaaggatt tactctggtt
    36061 gaattaaaac tagaaaccgg aagaacacac cagatccgtg tgcatatgaa gtatatcggt
    36121 tatccgttag ctggagatcc agtatacgga ccgaagaaaa ctttgaaagg caatggtcag
    36181 tttctccatg cgcaaatgtt aggttttacg cacccgacta caaacgaaaa gatgatcttt
    36241 gaagcacatc ttccagaagt ttttgaaaaa actttagaaa aattaagaaa aaacattgca
    36301 ttttaattta gataacggta tagtaattaa caacgaaagc ataaaactta atagaattcc
    36361 tttaagttta gtcccgtgag gctaagaagg gtgggagcaa ggatacgtat ggtgcgccat
    36421 aagtagattg ctcattgaca tagtatagct atcagtgtat cagtatacgc tcagtctaaa
    36481 cattcctcct gtcctcttag ggcaggagtt tttttatgca aaaaagtagg gggaatgaaa
    36541 atgcaagcaa aagaagtagt agatcaggta accatgaagc gagcattgac tcgaattact
    36601 tatgagatta tcgagagaaa ccatagtatc caagatatcg tattggtagg tatcaaaaca
    36661 cgaggaatct acattgcatc aagaattgcc gaacgcctga agcagctaga agatatcgat
    36721 attcctgtag gagaactgga tatcacttta taccgagatg acaaaaaaga aaatccagaa
    36781 gaaccggaac ttcattcttc tgacatccca gtttccttag aaggaaaaga agttattttg
    36841 attgatgatg ttttgtatac aggacgaacg attcgagcag caatggacgc agtaatggat
    36901 tttggcagac caagaaaaat ttcattagca gtcctggtcg atcgtgggca tcgagaattg
    36961 ccaatccgtg cagattatgt tgggaagaac attccaacat ctcgggcgga agagatttta
    37021 gtagagatgc aagagcttga tggacaagat cgcatcatga ttttgaaaga ggaagattag
    37081 aggagagaga aacatgtcgg agaaaaaagg atttcataat gatgacgtgg tgttagatat
    37141 ccacgatcgc ccaaccccag gacattgggt aggattaagt ttacaacact tgttcacgat
    37201 gttcggagca accgtgttag tccccatctt agtaggtatc gatccaggta ttgcgctagt
    37261 cagttcagga ctaggtacat tggtgtactt atttactact aaaggaaaga tacctgcgta
    37321 cttaggaagc agcttcgctt tcattgcagc gatgcagctt ttgatgaaaa cagatggtta
    37381 tccagcgatt gcacaaggag cagtcacaac tggattagtc tatttgattg ttgcgctgat
    37441 catcaaaaag atcggttcag catggctgga taaaatcttg cctccaatcg tcgtcggtcc
    37501 agtcatcatg gttatcgggt tgggacttgc ggcaaatgca gcaacaaatg ctatgtataa
    37561 tcagggcacg tatgatttca agtatattgc tgtagcgctg atcacattag gattaacaat
    37621 tttcttcaac atgtggctaa gaggttttct cggattgatt ccgattttac taggtattat
    37681 tagcggatac atcgtagcct tgctgtttgg aatcgtggat actaagccaa tcgtagacgc
    37741 tgcctggttt gctgttccta actttgagat tccctttgta caatatgaac caaagctata
    37801 tcttggagca atcacaacaa tggcacccat cgcttttgtg acgatgacag agcatatcgg
    37861 ccatcttatg gtattgaata aactaactaa acgtaatttc tttgaagaac cgggtcttca
    37921 taagacgttg acaggtgatg gattagcaca aatcgtggca gcctttgtcg gaggtcctcc
    37981 tgtaacaagt tacggtgaaa acattggtgt tctggctatc acacgtgtcc atagcgtgtt
    38041 tgtgatcggt ggagctgcag tatttgcagt cattttagga ttcgtaggaa aattaagcgc
    38101 tttgatttta agtatccctg gaccagtcat ctcaggaatc agttttatct tatttggagt
    38161 aattgccgca agtggaatga agattttaat cgagaacaaa atcgattttg ataaaaagaa
    38221 aaatctgttg attgcttcag ttatcttagt agtaggaatt ggcggactcg tctttgaagt
    38281 aggcacattt acattgtcgg caatggcatt agcaactgta cttggcatca ttttaaatct
    38341 tatcttacca gaaacttcac gaagcgaaga aaactaagga ggaaacatta tgatcatcaa
    38401 atcagaacgt atcagcttaa agcatttatt gaccgttgag gcacttactg atcaagaagt
    38461 tatgggcttg atccgcagag ggcaggaatt caagcaaggt gctaattgga ctccgcaaaa
    38521 gcgccagtac tttgctacaa acctcttttt cgaaaatagt actcgcacac ataaaagctt
    38581 cgatgtagcg gagaaaaaac tagggctaga agtgattgaa tttgaagcaa gcacaagctc
    38641 tgtccaaaaa ggggaaacac tatacgatac agtactgacg atgtcagcat taggcgtaga
    38701 cgtagcggtt atccgtcatg gtgatgagaa ctattatgac gaactgatac aaagtaaaac
    38761 aatccagtgt tcgattatca atggaggaga cggaagcgga cagcatccaa cccaatgctt
    38821 gcttgatttg atgaccattt atgaagaatt tggtcatttt gaaggtctga aagttgccat
    38881 cgtaggtgat atcactcact ctcgcgtagc taaatccaat atgcagatgt taaaacgtct
    38941 aggcgcacaa gtattcttct caggtcctag agaatggtac gacgatgaat tcgaagtgta
    39001 cggacattat atgccattgg atgaactact agatcaagtt gatgtcatga tgatgcttcg
    39061 ggtgcaacac gaacgccatg atggaaaaga aagtttctca aaagaaggct accatcagga
    39121 acatgggtta acagttgagc gtgcgaagaa gttgcaaaaa catgcaatca ttatgcaccc
    39181 agcaccagtt aaccgtgatg tagaattagc tgattcatta gtggaaggat tacagtcgcg
    39241 gatcgttcag caaatgagca atggagtatt cgtcagaatg gcaatcttag aagcagtgct
    39301 aaatggaaaa gcgtaattat aggaggatga aaaaatgaaa acactcatta aaaacggtca
    39361 gatcaataca cgaaaaaata tgacgacacc agcagaaatt tggatagaag atgggcgaat
    39421 caaagcaatc ggtacaggat tctcagaagc cgaatttgat gaagtgtttg atgcaaaggg
    39481 acaattgatc acacctggtt tagtggacgt ccatgttcat ttgagagagc caggatttac
    39541 atacaaggag acgatcgaag ctgggactcg ctcagctgct cgtggcggtt tcactactgt
    39601 atgcgcgatg ccgaatttaa atcctgtacc tgatacggca gaaaagctga gacaagtata
    39661 tgacatcatt agaaaagatg cagttgtgaa ggtattgcag tatgcgccaa tcacagaaaa
    39721 tctgcgaagt gagaaattag ttgatcaaga agcactgatt gaagaaggtg cttttgcttt
    39781 cacaaatgac ggtgtaggtg tccaaacagc tgggacgatg tatctggcta tgaaagaagc
    39841 tgcaaaaaac aataaagccc tagtagccca tacagaagat gaatctttat tatttggcgg
    39901 cgttatgcac gctggcaaga aggcagaaga acttggtctt cccgggatct taagcgtaac
    39961 cgagtcttct caaattgcta gagatctgtt gctagctgaa gcaactggtg ttcattacca
    40021 tgtttgccat gtttctacta aagaaagtgt ccgtgtaatc agagacgcaa aaaaagcagg
    40081 aatccacgta acagcagaag tttcacccca tcatcttatt ttgatcgacg aagatattcc
    40141 cgaagatttc ggcttttgga aaatgaaccc gccgctaaga ggacgggagg acagagaagc
    40201 tttgatcgaa ggcttgcttg acggtacgat cgattgcatc gctacagacc atgcccccca
    40261 tggattagaa gaaaaaagcc aaagtttcat gaaatcacca tttggtatcg taggaagcga
    40321 aacagcgttt caactgatct atactcattt tgtagaaact ggtcgattca cgttggaaca
    40381 agtgatcaat tggttggcag ttaaaccggc tgagattttt ggtttgaatg caggaacgct
    40441 aacggttggt gcccccgctg atgtagcagt ttttgatatt acacaaactt gcacgatcga
    40501 taaagaagac tttttatcaa aaggggagaa tacacctttt atcggctgga aagtaaaagg
    40561 cgaaacacaa atgacttttg tcaacggaaa acttgtgtgg cagaagggag aataaaagta
    40621 tggaacgttt gcttatatta gaagatggaa cagttttcga aggaaaggct tttggtgcag
    40681 atgctagtgt cttcggagaa atcgttttta caacaagtat gactggttat caagaaacta
    40741 tcactgatca aagttttaac ggtcaaatca ttacatttac ctatcctatg gtgggtaatt
    40801 atggggtaaa tagagatgat tatgaatcga tttctccaac atgcaaagga gtagtagtaa
    40861 aagaacatgc acgtgtagct tcaaactggc gaaaccaaat gacgctagat tcatttttga
    40921 aacaaaaagg aattcctgga atatcaggta tcgatacgcg cgcccttact cgcaaaatcc
    40981 gtgaagtcgg aacgatgaaa gctagtatag ttgatgctgg agattccttc gaacatgcat
    41041 ttgatcagct gaaagcaacc gttctagcaa ccaatcaagt gcagcaagtc tcaactaaca
    41101 aaccttatcc aagtccagga acaggtcgga aagtcattgt cattgacttc ggcttgaaac
    41161 atagtatttt acgagaattg agtaaaagaa actgtaacct cacagtactt ccctataaca
    41221 cagatgccga gacgatttta gcgctatcac cagacggagt catgctgacg aatggacctg
    41281 gtgatccaaa agatgtgcca gaagcaatcg aaatgatcaa aaaaatccaa ggaaaagtac
    41341 cgatttttgg tatttgtctc ggtcaccagt tatttgcttt agccaacggt gcagatacct
    41401 ataaaatgaa attcggacat cgaggattaa atcacccggt acgagaagta gcgaccggaa
    41461 gaattgattt tacttctcaa aatcatggct atgcagtcga tgaagccacg attgatccag
    41521 aaaaactcat cgtaactcat gtagaagtaa atgacggaac agtagaagga gtcaaacaca
    41581 gagattatcc cgctttcagt gtgcagtttc atccagatgc tgcccctggt ccgcatgatg
    41641 cactacattt atttgatgaa tttatggaaa tgatggacgc aggaaaggag cagtaaacag
    41701 atgccgaaac gtacagatat caagaaaatt atggtgattg gatctggtcc gatcatcatt
    41761 ggtcaagccg cagaatttga ctacgcagga acacaagcct gccttgcctt aaaagaagaa
    41821 ggatatgaag tggttttagt aaattctaat cctgcgacga tcatgacgga taaagaagtg
    41881 gcagatcaag tatatatcga accgatcaca cttgaatttg tatcaaggat tcttcgaaaa
    41941 gagcgtccag atgctctcct tccaacttta ggcggacaga caggcctcaa tatggcaatg
    42001 gagctggcag catcaggtat tttagaagaa ttgaacatag aacttctagg aacaaagctt
    42061 tctgcgatcg atcaagcaga agatcgtgat ctattcaaac agttgatgaa agaattgaat
    42121 cagccaatcc ccgagtctga aatcgtcaat acagtagaag aagctgtaga ttttgcaaat
    42181 aaaatcggct atcctgtcat cgttcgtcca gcctttactt taggcggaac tggtggaggt
    42241 atgtgtgaaa atgaagaaga attacgtatc gtatcagaaa atggattaag tctttccccc
    42301 gctacccaat gtttgattga acgaagtatt gcaggtttta aagaaattga atatgaagtg
    42361 atgagagatt cggctgataa tgcaatcgtt gtctgcaata tggaaaattt tgacccggtg
    42421 ggtatccata caggtgattc tatcgtattt gcccctagtc aaacattgtc tgaccatgaa
    42481 tatcaaatgc ttcgtgatgc ttctctttcg attattcgag cacttaagat cgagggaggc
    42541 tgtaatgtcc aactcgctct tgatccacat agttttaatt attatgtgat tgaagtcaat
    42601 ccgcgtgttt ctcgttcatc tgcgttagca agtaaggcga ctggctatcc gatcgctaag
    42661 ctagctgcta aaatagcgct tggattaaca ttagacgaaa tgaaaaatcc tgttacagga
    42721 acgacttttg cagaatttga acctgcatta gattatgttg tagctaaaat tcctcgctgg
    42781 ccgtttgata agtttgaaaa cggagaacgg cttttaggca cgcagatgaa agcaactggt
    42841 gaagtgatgg ctatcggtcg gaatatcgaa gagtctttat tgaaagctgt gcgttcttta
    42901 gaaatcggta cacaccatat cgaacttcct gagttggcag acatcacgga cgatgaccta
    42961 atccaaaaag tggttcgagc acaagatgat cgcctgtttt atgtagctga agctattaga
    43021 agagggtaca ccatagaaga attagcggat ttgacaaaaa tcgatttatt ctttttagat
    43081 aaactgttgc atatcgtaga aatcgaacag cagttgaaac agcagccgtt ggatgacaag
    43141 atattgaaaa cagcgaaaca aaacggtttt acagacaaaa aagtggcgga gctgtgggaa
    43201 ataaacgaag aagccgttcg ccagatgaga aaagaaaatg atttgattcc tgtatataag
    43261 atggttgaca cttgtgcagc ggaattcgaa tcaaaaacac cttattttta tagttcctat
    43321 gaatatgaaa atgaaagttc acgatcagaa aagccctcaa ttctagtact gggatctggt
    43381 cctatccgta tcggacaagg ggttgaattt gactatgcga ctgtgcattc tgtcaaagca
    43441 atccagcagg caggatacga agcaatcatc atgaacagca atcctgaaac agtttcgact
    43501 gacttttcta tttcggataa attatatttt gagccattga ccttcgaaga tgtgatgaat
    43561 gtgatcgagc tagaacagcc gataggagta atcgttcaat ttggtggtca gacagcaatc
    43621 aacttagccg aacctttgac tgctgctggt gtaaaaatct tagggacaac gatcgaagac
    43681 ttggatcgtg cggaaaatcg tgatttattc gagcaagcgc tgaaagagtt ggatattcct
    43741 caacctttag gggatactgc tacaagtaaa gaagaagccg tggttatcgc ttcgagaatt
    43801 ggttatccag ttcttgttcg tccaagctat gtattaggcg gacgtgcgat ggaaatcgtt
    43861 gaaaaccagc gagatttaga agattacatg gaacatgctg tgaaagcatc tccagaacat
    43921 ccagtactag tggaccgtta cttgcttggt ggtgaatgcg aagtggatgc gatttgtgac
    43981 ggtgaaacag tactcatccc agggatcatg gagcatattg agcgtgctgg tgtccattca
    44041 ggggattcaa tggctgtgta tccacctcaa acattatctg aatcgatcaa gaaaacgatc
    44101 gaagattaca cgatccgctt agcattaggt ttgaattgtg tcgggatgat gaatatccag
    44161 tttgtcatcc atgaaaatga ggtttatgtg atcgaagtca atcctcgagc aagtcggact
    44221 gttccattct taagtaaggt gacaggaatt ccaatggcac aaattgcgac gaaagctatt
    44281 ttgggagaga aactaaagac acttggttat gaaaacggac tttatccaga aacaaaagaa
    44341 gttcatgtta aagcacctgt cttttctttt acgaaattgc agaaagttga tacttactta
    44401 gggcctgaaa tgaaatcgac tggagaagta atgggatctg acagacaatt agacaaagct
    44461 ttgtacaagg cattcgaagc ttctggatta cacttgcctg aatatggagc cgtattattt
    44521 acgattgcgg acgaaacaaa agaagaagca ctagaattag ctaaacgttt tacagaaatt
    44581 ggctatagtc tgataggaac gaaacataca gctgcttatt tcgaaaaaaa tggtctggtc
    44641 gttgaaacag tagcgaaaat ttctgaggaa gcagcagaaa aaaatgtagt cgacttaata
    44701 agagatggta aaacacaagt ggttgtcaat acgattgata aagatcgggg aaatgcttct
    44761 aaagacggtt tcatcatccg aagagaagca gttgaacatg gtattccatt gtttacttct
    44821 ttagacacag cagatgcgat cgttcgagtg atggaatccc gtgctttttc aactaaccct
    44881 atttaacggc gagcacatgt taagacaaaa agacgaaaaa ccgttgcagg aggggacaga
    44941 tgaaacaaga aatgatggaa atcgttcagc aaaaacagct ggcaccaaag atttttgaaa
    45001 tgacattgaa aggtgatcta gtaaaagaaa tgcagcaacc aggacagttc ttgcatattc
    45061 tcgtgccgcg tgcagacttg ctattacgcc gaccgattag cttgaatcat atcgaccacg
    45121 aaacaaatac ttgccgtatc atttatcggg tggaaggtga ggggactaga gtcttctcta
    45181 ctctttctgc cggagaccat ttagatgtca tgggtccttt aggcaatggt tttgatttgt
    45241 ccaatcttca tacaggagac gaagtattta taatcggtgg aggaatcggt gtccctcctc
    45301 tatatgagtt atcaaaacag ttagtcgaaa aaggaattaa gccaacgcat tttttaggtt
    45361 ttgccacaca tgaagtcgtt tattatgaaa aagaatttaa tcgtctagga gaaacaagaa
    45421 tcgctactga cgatggaaca tacggtatgc acggaaatgt cggtaattta ttgttaggaa
    45481 cgaagacgga acctacagct gtttttgcat gtggttcaaa cgggttattg aagacagtgg
    45541 aacagctgtt ttcttcgcat caaaatgtcc agttatcatt agaatcccgc atggcatgtg
    45601 ggataggggc ttgctatgct tgcgtttgtc atacgccgga agatgaaaca ggaacaaaaa
    45661 gtgtgaaagt ttgtgacgaa ggaccgattt ttaaaatagg agaggtaatt atatgaatga
    45721 gaatccttta gcggtcaaac ttcctggcct agaattaaaa aatcctatca tgccggcaag
    45781 cggctgtttc ggttttggca aagaatacgg aaaatactat gatttgaatc agcttggatc
    45841 gatcatggtc aaggcaacga ctccaaatgc ccgctttggc aatcccacgc caagagtggc
    45901 ggaaacacca tctggcatgt tgaatgcaat tggtttgcaa aatcctggtc tagacgttgt
    45961 tatgcataaa cttcttccag aattagagga gtacaatgag ttacccatca tcgcaaatgt
    46021 tgctggtgct tgtgaagaag actatgtaga agtttgtagc aaaattggcg aagcaccaaa
    46081 tgtgaaagca atcgagctga acatttcttg cccaaatgtc aaacatggcg gaattgcttt
    46141 tggaacagat tctgatgttg cttttcaatt aacacaagca gtaaagaaag tttcttctgt
    46201 tcctgtctat gtcaaattgt ccccaaatgt aacagacatc gttccaatcg ctcaggcaat
    46261 cgaagctgga ggggcagatg ggtttacgat gatcaatact cttcttggta tgcggattga
    46321 ccttaagaca agaaaaccga ttttagccaa tcaaacaggt ggactctccg gaccagcaat
    46381 caagcctgtc gctattcgtt tgattcacca agtagcaagt atatccagcc ttccaatcat
    46441 tgggatgggc ggcgtgcaga cagtggatga tgttcttgag atgtttatgg ctggagcaag
    46501 tgctgtagct atagggaccg cgaatttcac cgatccgtat atctgtccta aactaattaa
    46561 agagctccct gtgcgaatga gcgaactagg catcgaatcg ctggaaagat taatcaaaga
    46621 agtgagagag gaacgtgaac gatgaatcaa ctagaccaac gaccaattat tgcattagat
    46681 ttttcaacta ggcaagaggt agaagacttt cttcgatttt tcccgaaaga agaaaaattg
    46741 tttgtgaaaa tcggaatgga attgttctac caagaaggac ctgaaatcgt acgttatcta
    46801 aaagaggctg gtcataatgt atttttagat ctgaaacttc acgatattcc gaatacggtc
    46861 gaaaaagcaa tgcggggatt ggcaaagctt ggtgttgatc tcacctgtgt tcatgccgct
    46921 ggcggtattc gtatgatgga ggcggcaatg cgaggattag aagaggggac tccagaaggt
    46981 ggaaaacgtc cgctacttct agctatcact cagcttactt ctacaagtga agaagaaatg
    47041 catgccgatc aactaatcga agtttcttta gaaaaaagtg tgatccatta tgctagctgt
    47101 gccaaaaaag caggattaga tggtgtggtt tcttctgctt gggaagtaga agcgatcaaa
    47161 gaaatggcag gagacgaatt tgtttgctta actccgggta taagaccaga aggaacagtc
    47221 gcaggagatc agacaagagt agtcacacct tctcaggcaa aaaagatcgg ctcaactttt
    47281 atcgttatag gtcgaccaat cactcagtca actaatcctt ataaagcata tcaaacgatt
    47341 caaacagaat ggagctaacc taaaatgaat gttgaacaaa gtatcgcaaa agacttatta
    47401 gaaattgaag cagtattttt aaatccaagt aatcctttta catgggcaag tggaatcaaa
    47461 agcccaattt actgtgataa ccgaatcacg atgagctatc caaaagtccg aaaagagatc
    47521 gcaaaaggat tagcaagcaa aatcaaagaa gcttaccctg aagtacaagt gattgctgga
    47581 actgcaacag caggaatccc tcatgccgca tgggtagcgg aaatactgga tttgccaatg
    47641 gtctatattc gaagtaaggc gaaagatcat gggaaaggta accaaatcga aggacgtata
    47701 tttgaaggtc agaagatggt tgtgatcgag gatttgattt ctacaggcgg aagtgtcttg
    47761 gaagcagctg aagcagcaaa aagagaaggt gcggatatcc ttggtgttgc ggctatcttt
    47821 acgtatgagt tgccaaaagg aaaagcaaat ttcgaaaaag ccgaaatccc tcttatgacg
    47881 ttgaccaatt attctgtatt gattgaagca gctttagaag atcgttatat cgatgagcaa
    47941 gaattaactc tgctaaaaga atggaaaaaa gatcctgaaa attggcagat ttaagcgcgc
    48001 ttgatgaaga tagagaaatc cgatttgtgt ctccagaatc atcaattgga atagcaaaaa
    48061 tccaaaaact gattgcgaga agcatctttt catcaggtat gaaaagaaac ttctatcgtg
    48121 atcagttttt gattttttta aaattcattt ttctaagact ggttagcaga aagaagagaa
    48181 taatctcttc tcttttttct attatatata gattttctct attttttggt aagggagctg
    48241 tttcaaaaat ggtaaagagc ggaaatgttg cgaatatcag ttatttaatg atatgatatt
    48301 cggaaaaaga aatctcaaag ggaggtaact tttatggggt tgaatgaatt tattttagga
    48361 ttgaacaatt tagagacgat cacaagggca cctggatttt ttaaatatac agagcataca
    48421 gttgcagcac attcgtatcg tgtagcatct attgcgcaag ttctaggaga cattgaagaa
    48481 gcgaatggac aaccgatcga ttggaaactg ctctatgaaa aatcattgaa tcatgactac
    48541 acagagcgtt ttattggtga tatcaaaacg ccggtgaaat acgcaagcaa agagttaaga
    48601 gggatgctgc aaacagttga agaaaagatg acggacgaat tcatcaacca agagattcca
    48661 gctgagttcc aagaagttta tcgccgtcgg ttgttcgaag gaaaagatga aaccgtagaa
    48721 ggagaactat tagccatttc agataaggtt gaccttcttt atgaatcttt tgatgaaatc
    48781 atcaaaaata acccggaaaa agtttataag gagatgttca ttgaggcagt gactacgatt
    48841 aaaagctttg aacatcggcc ttctgttcag tatttcttta aagagatatt tccggaacta
    48901 ttgaaccagg aattttatgg aaaagaggcg tttttagaaa ccgtctcaac gattgtaaag
    48961 aaagaagaaa aataaaaatg atatgagatg cagggggaag tatagttgaa aaagaatatg
    49021 gatgtcgaat ggggctattc tggagacaaa ggtccggaaa attgggcgag tttatgtgat
    49081 tggtttgcga gaggtgcgga atttccattg cagtcgccta ttcatttgac caagggggaa
    49141 gaaaccaaaa tagaaggaga cacgctttcc tttcattatc aaaagcaacg gtttactgac
    49201 aaggaattca aaaacacgat tcatttagta ccttttgacc aactcagtta tgtagagttc
    49261 aagaaagaac gctattattt gacagatatt catttccact tgccttctga acatatcatc
    49321 aacggaaaac aggaagatat tgaatttcat tttgttcata tgaacagcaa aaaagagaat
    49381 ctagttgtgg gtgtcatgta ccagctaatg gtacaggaag gttggctgta taatcaagaa
    49441 aatggggaaa gttggaactt agaaaaacat gagcattggg taaatccgga tgtgttcttt
    49501 ccggagcaaa aaagccattt ccattatatt ggctcattga caactccgcc taccagcggg
    49561 ccaatccaat ggtttgtaat ggatcatgta ggaaaactga accaagagtt tcttctcccc
    49621 ttcgatggtc agtatgctcg accgaacaac cgaccaatcc agcccttgaa tggaagagaa
    49681 atttattatt tcgaggagtt tgagcaatga atattcagca gatgaaatac gtggtcgctg
    49741 tagcaaacaa tggtagtttc agagaagcgg caaagaaaat gtttgtctcc cagccaagtc
    49801 tttcagctgg tatcaaagaa ttagaaaccg agttagggat cacgctgttt actcgaacga
    49861 atcgaggggc atatttaaca gaagaagggc aagacttctt aaatcgtgcc gagaaaatat
    49921 tggtccagct tgatacatta gaaactcact atctaacgag tgaaaagaga gacaattttt
    49981 cgatcgctgc ccagcattat gatttcttag gtcctttgac cgcacagcta ctcgaggaat
    50041 tcaaagacga gatcaaacaa tttcggatca tggagacgac aacagcgaga gtgatcgaag
    50101 aagtcaaaga gcagcacagt gagatcggca ttatttatat gaatgagcat aatcaagctg
    50161 gtatcagaag atatttacaa caaggagagc taagtggccg cagcattgga aaattcaaaa
    50221 cgcatatttt tttaaggcaa ggacatccat tagctgaaca cgcagagatc accaaagaag
    50281 aattgttatc ttatcctcaa gttcgtttta cacaggatgg aaataatttc ccgtattttt
    50341 atgaagacct tatcgagatc cctgatcaag aaacagtgat ttatacgagt gatcgaggta
    50401 ctttgatgaa tatcgttctt gaaactgatg cttacgcttc aggatctggt attgtgattg
    50461 gagggattcg cgagcacttg cggttaatcc ctttggcaga aggcgaacta aatgaatttt
    50521 atatcattta ttcggcgaaa cgtccgctca gtgaaatcgc tcaaagattt atcaaagagc
    50581 ttactcggtt actggaccag cagagctaag aaaagcagat gagaacgctg tttattgaac
    50641 accgttgatc aaaaaagagg ggttgtgaca gaattttgtc acaactcctc tttttgtagc
    50701 aaacaattta taactaattg ctgttgtggg aaagtacgca aatatgattc tagaaacact
    50761 cattgattac ctgttttgtt tcatagttgt aattttttct tcttctggtg tcacgataat
    50821 cgtcttttgg ttttcataaa taacataacc aggcttggcg ccatttggtt ttcggatatg
    50881 ctttacctgt acaagatcaa ccggcacttg ggcagagtat cggtattttg aaaaataggc
    50941 agctaactcg gcagcttctg taattgtttc atctgagggc ttgtcacttt taatgatgac
    51001 gtgcgaaccg ggtatatttt ttgcatgaag ccaatagtcg gtttttttag ctgtcttcat
    51061 tgtcagctgg tcattttgaa gattgttttt accaacaaga atgagcgttc cgtcagaaga
    51121 aaagtattga tcaggctgag atggtttctt acgtttttgt ttttttaagt tcttcttttt
    51181 caggtatcct tctgaagtca attcttcttt aattgcttcg atatccattg ggccggcaat
    51241 ttccagttga gataagacag attcaagata ttggatttca tctttggctt cttggatttg
    51301 ttcgccaatc agcttaacag cgttcttcag cttttggtat cgatggaaat atttctgtgc
    51361 attttgattt ggtgtcaatg ccggatctag tgctattttg attggccgat cttcttcata
    51421 ataattaggt aaaacaactt cttttgcgcc gcgtggtact tgtgtcagaa aagtagtaag
    51481 tagttcgcca tttctacggt aattctcagc gttttcggat tctttgagtg tttgttcacg
    51541 ttttttcaat ttatttttat ttcgttttag ttcattttcg atttttcgaa tcagttctcc
    51601 gccttgttgt tttgcccgat ctttctctgc tttttcgtga taatagctat ctaataattg
    51661 actgagtgtt ggataagctg ttacagcaga tgcctgttcg gacaatacct gataagcaat
    51721 cggtgtgaaa aaatctttat tttccgtttc gtaaaaagta ggaataggct gatggctgat
    51781 ggctgagaaa aattcgtccc atacaaccat cttttcatta ggacgttcca gtaatctttt
    51841 ggtcagctct tgagcgatat cgaaaccgat tccctgaaac tgacgttgga ttgcttttgg
    51901 atctagttca gtttgggaaa gccgctgaaa gattttttct ttctcggagc taaatgggtt
    51961 caagacctct tgttttggcg gagcaacata ttctacacca ggaagcaaag aacgataagt
    52021 gttttgagag cttccaatgt gtttgatcgc atccagtatt tttccagttt ctcgattaac
    52081 taagacgatc gtactatgac gtcccattaa ttcaacgatc aatatgatat tttgtagatc
    52141 acccaactcg tttcgtttag caaagtggaa atggatcact cgatcatttt cgatttgttc
    52201 gatgtcttct aaaatagcgc catccaaata ttttcgaagc atcatcacga agttaggcgg
    52261 attatcagga ttctgataat cgatttgggt aatctgtaca cgagcataac ttgggtgcgc
    52321 agataataat aatcgatggt ttttgccgcg tgaacgaatc accagcacga tttcattttc
    52381 ataaggctga tggattttcg agatccggcc agatagtaac gtttcacgca attcgttgac
    52441 catcgcgtgg gtaaatacac catcaaagga catggttcat tcctcatttc ttttcataag
    52501 tatattcatt ataacgaaaa aaagaagaaa aaccaatttg gccgaatagt aaagcaaaag
    52561 tctagaaaaa tcttggacta attacataaa aaacagtgtt tctatcgttg aaatccaaat
    52621 ttttaggtat aataaaaaat aggagaaaaa gtagaaaaga aggtgtttgt tatttgggaa
    52681 gtagttaaat cgagagtaca agaaatgaat gaacatttct cagtgtcatt cgcagaaaat
    52741 ccaagtaagt attttcgacg tcttgttttt ctgctcatct tatcattgct gttaacagtt
    52801 gcaatgtttt tattgccgga aaaaatccga gaagagcaag taaatagtct cgtttattcg
    52861 tccataccaa ccagcaaatt gaaacctttt gattacagca aagctgatca gaaaatcaaa
    52921 caaagccggg cgatatcggt gatgttcagc aaaccgaacg ggaaaaccta tcaggacatg
    52981 cttgatgttt ttaatgatcc tgagcttatg gaagaattga atcgaccgat cttttattat
    53041 ccgatcgttt atgatgtaca tgaactggaa caaaaatata acatacgaac ggatgaagtg
    53101 acatttattt tctttgatgg aggaaaagaa gcaaatcgga taactgcggg taagggagga
    53161 ataactgatt ttgataagga gttgatccct gaactgaatc gacttccgtt agccaatatc
    53221 aaacaattag aagaagaatt ggatagaacg ggagtaactt cccaaaattc cgagattgct
    53281 aattgagaca ttggcgcgat gaaacggtgg gtctatatag cgctattttt aattatcaga
    53341 acaagtgatg tttgatcttc aaaataacaa ataaaaaatt aaaaaatata gttgacgaaa
    53401 ttcaaaaatt cgattagact taaatcaatt cttaaggaaa gggtgacctg taatgaactt
    53461 atcaaaacgt atttcagcag aaaacaaaaa aaattggcgc agctggcgta gataagttgt
    53521 attaatggtg agactttccc atagatacaa ctttttagag tgcatttcta aagcttgtat
    53581 ctatgctaga catgaacatt gactgccgca tagattagaa tctatgcggt tttttgtgta
    53641 aagacaatga ccgctttggc cattgtcttt ttttgtagac tggatacttg cctgattata
    53701 ataaataaaa agattgactt tgcaggagga aaaaaatgaa aaacaaacga ttaataacag
    53761 ttgtagtaat tattttagtt tatttagcag gtgcatttat ttatggaaaa gcctcaggcg
    53821 aaaaagaaag tacttcgacg aaccagacaa aaaaaacaac agttgttggg gtattgcaat
    53881 acgtgagcca tccggcatta gatgagattt atcgaggaat caaagatggt ctgaaagaag
    53941 aaggattaaa agaaggagaa aatcttgaga tcaaatttca aaatggacaa gccgatcaga
    54001 gcaagctagc cacaatgagt caacagctag tacaatctga tccagatgcc ttgattggaa
    54061 tcgcaacacc tgccgctcaa tcattagcaa acacgacttc atcgatccca gttgtgttag
    54121 gtgctgtaac ggatcctgtg ggggctggat tagtcgcttc tttagagaaa cctggtggta
    54181 atgtaacagg tgtttctgat cagccgcctg ttacttcaca aatcaagctt gcttctgatt
    54241 tgttgccaaa tgcaaaaaaa gtcggaatct tgtatgcttc ttcagaggat aattcaaaat
    54301 accaagtagc acaagcagaa gaagctgcaa aaaaagaagg gttagaatca gtaaaatatg
    54361 cggtgccttc cactaatgag attgcacaaa cggttcaagt gatgagccga caagtcgatt
    54421 ttatctatgt tccattagat aataccattg ccaatgcgat gcaaacagtg gtaaaagaag
    54481 caaacaaagc aaatatcccc gtcattccat ctgtggatac aatggtggaa caaggtggac
    54541 tagcaacaat cgggatcaat caatatcaat tagggcttca aagcggtaag atggcggcag
    54601 aacttgcgag tggaaaagaa aaaccggaaa cgacgcctgt ttatacattt gatcaagggg
    54661 atacagtgat caatcaatct caagctgatc gcttaggaat cattgttccc caatcgatga
    54721 aggaaaaagc caaaatcatt acagatgact cgcagcaaga aacatctaag gaggatgaca
    54781 aatgatcgta tcagctattt cacaaggcat gctttgggca atattaggat tagggatttt
    54841 catgacttat cggatcttag actttcctga tatgacgaca gaagggtcct tcccattagg
    54901 tgctgctgtc tgtgtgacag ctattactca tggggtagcg ccgattgtag ctacattatt
    54961 aggcgtaggt gctggcatga tagcaggact cgttacgggg ttactttata caaaaggaaa
    55021 gataccggtt attttagcag ggattttagt gatgtcagga ttgaactcag ttattttgtt
    55081 tgtgatgcga acaccaaatc tttctttatt gaatcatccg attctacaag acagcttcca
    55141 tcgctttggg ttacctgatt actttgacac agtccttctt ggcttcatct ctttgggcat
    55201 cttgattgct gtactgctat tcttcttcaa tacagatttg ggtcaaggct atattgcgac
    55261 aggagacaac gaaacgatgg ctcggtcgtt agggataaaa accgatcgta tgaaaatttt
    55321 aggtttaact ttgtcgaacg gtgtcattgc attatccggt gcgctgattg cccagaacga
    55381 cggatatgca gatgtaaata aagggattgg cgtaatcgtc atcggtcttg cttccatcat
    55441 catcggtgaa gtgatcttcc aagaattgac gctagcagaa agattgattg ctattgttgt
    55501 cggcagtatc atttatcagc tattgatttt agtagtaatc aaactagggt ttgacacgac
    55561 ttatctgaag ttgttctccg ctatcatctt agctatttgt ctgatgatcc cgcaattgaa
    55621 gaaagcactg aacttaaaaa cgggttttga gaaggaggca tagtaatgac tgatatattg
    55681 acaatcaaaa atggcagaaa agtcgtaaac aatggaatga atgaagagaa agtactattg
    55741 gatgaaatta accttacaat cagagaaggg gacttcatca ctgtccttgg cgggaatggt
    55801 gctggaaaaa gcacactgtt caatacgatc gctggtacgc ttcaactcag tcaaggatcg
    55861 atctctttta aagatcagct gatcacaaaa gattcagaag aaaaaagagc acgattcctt
    55921 tctcgagttt tccaagaccc caagatggga acggctcctc ggatgacagt agcagaaaat
    55981 ttgctacttg cacaaaaaag aggtcaaaaa cggaaattcc gtttacgtaa cttgaaaaat
    56041 caaaaagaag attttttcag actatgtcaa gaagtcggta atggcctaga gcaacacttg
    56101 gatactccag cgggtgaatt atctggtggt caacgccaag cattaagctt gctgatggcg
    56161 acgatcacag ctcctgagtt actattatta gatgaacata ctgcagcttt agatcctaaa
    56221 acagctaaag cattaatgcg attaacaaat cagcggatca atgaacaaaa attgacttgt
    56281 ctcatgatca cgcatcgaat ggaagacgcc ttgaaatacg gaaatcgtct gatcgtactc
    56341 caaaaaggga aaatcgttca agatatttct gaaaaagaaa agcaacattt gacaatgggc
    56401 gaccttttgc agttctttga agaagtagtg gattgatttc gacagaaaaa ttcctttcag
    56461 tagaaggact tgaaaactca ttgacatctt cctttgattc atcctatact taaaacaata
    56521 aacaattaaa catatttggg tgttttgtag gatcacgtag tcaatgattt taacaattaa
    56581 atagaatatt ctttgctctg acaagtaaac gatgagaaaa gaatttgcta ctttgccacc
    56641 tagacgtttc gtactttttc gtatcaaacg ctaagtggct ttttttattg aagtaagaac
    56701 aaaggaggaa taagatgatt tctggacaaa ccaaattagc tgggctcttt gctgatccgg
    56761 cttctcacag tttatcccca ttgatgcaca atactgcttt tgaagcaaac aacatcgatg
    56821 cggtgtattt agctttccaa gtaaatccaa tgaatttgaa gcaagcagtc gaaagtattc
    56881 gaacttttga tatgttaggt gtaaatcttt cgatgccgaa taaaacagcg gttattcctt
    56941 atctggatga ggtaagccag gaagcgcaat tgatcggagc agtgaatacg atcgtgcacg
    57001 aaaagggtcg tttgattggc tataatactg atggtgcggg cttcatgcaa tccgtgcaag
    57061 aagctgggat ttcgatcaaa aagaaaaaaa tgactctact gggagctgga ggtgcagcaa
    57121 aggcagtcac tgttcaagca gcgttagacg gcgctgagga aatcgtagtt tataaacgaa
    57181 acaaccaaac attcgctcaa gtaaaagaaa cattcgaaca actcagctat cgaacttctt
    57241 gtaagataaa agttcgtgac tttgccgata cgcatcaatt aagaaaagac ttgaaagaaa
    57301 gctgtcttct agtcaatgca acagatatcg ggatgggaaa gaaaatcaat cagtcaccgc
    57361 tcttagatat aagcatgatg catgagaatc tagcggtttt tgatttgatt tatgcaccta
    57421 gagaaacacg tttattaaaa gaagcaaaaa aagtaggagc aaaaggatac aatggacttg
    57481 gcatgttgat ctaccaagga gcaatcgcgt ttgaattatg gacaaaggaa aagatgccga
    57541 tccatgtgat tgaaaagctg tttgattaaa aaaggataat agataaagat cttttattct
    57601 cgcataaacg gtctcaagaa aagtaatcct ttatgtatcg aagcatttat ttcgttattt
    57661 tttattaaat tatcaaaaaa tgataggctt ttgtcgattg gttatcgtat cctttattta
    57721 tcagtaagaa acgaggagga accacaatga gtcggatgga tcgctataag gacatccata
    57781 agaaggcgaa acctctgaag cgggatacgg ggagtatttt tgctagaaga gaacgaaaac
    57841 gaacgcgtat ggaaaatgag gaagatgcta cccgtattta tgaaagagag cagcattcat
    57901 ttgaacattt gaaccaatac gagcaacaga tatacagaga tgcaccaaga gcagaagaac
    57961 aacaaaaaaa taaaaaattt ttcaatcggc aaaagaagaa caaaccgtta aaacctcgaa
    58021 gaaagcgatc gtggaaaaaa atcattctat cgattttgct tgttttgatc ctttattcag
    58081 gtatctcatt ttttattggt aaatatgtag ctgaacatga cacaagctta gaggcagcga
    58141 cttcagaaac ctttcatggg caaaaagcga cgaatggtgc gcataatatt ttgatccttg
    58201 gaagtgatac acgcggagaa gatgccgggc gagccgatac gatcatggtc ttacagttgg
    58261 atggtccttc ccataagccg aaactgattt cttttatgcg tgacagcttc gttacgatcc
    58321 caggggtagg acaaaataag atcaattcag cttatgcata cggaggagcc gatctagtgc
    58381 gtcaaacttt agtagaaaat tttggaatcg attgtcaata ctatgcgaaa gtcgatttca
    58441 aatcgtttga aaaagtgatc gatgccttat tcatgaacgg agtgaagatc gatgcagaaa
    58501 aagatctgaa tctggatggt gtagatatta aaaaaggggg ccagaagatg gatggacatg
    58561 ttcttttgca gtacgcacgt ttccgaatgg atgaacaagg agactttggc cgtgtcagac
    58621 gccaacagca agtaatgaac gctattttca gccaattgaa gaatccattg aatctgatcc
    58681 gtgcacctta tgcagctggt aaagctttag gatatacatc cacagatgtc actgcttggt
    58741 tcttgacgaa aaacctcttt tcgattgcac gaggagctgg tggcattgat cgaataagtg
    58801 tgccagtaga cggttcgtgg aattatgggc aaagtgatta tgctggcagt attcttgaaa
    58861 ttgataatca aatgaatcaa tctgctatta cagatttttt gaataaatga tcataaaaaa
    58921 gatcaagaag aagctgcgca aggcttttgt catgaatcaa tcaaacgatt cactcgtaaa
    58981 aaacgctttc ttatggtaga tttaaccaag agaggagctg tttacattgg atatctatct
    59041 gaacttcaaa aatgagtcgc gtgaagccat cgctttttat gaaaaagttt ttcagactga
    59101 agcatcaggt atcaccacat acggtgaaat gcctggaata gaacaaatga acttgccaga
    59161 agaagcaaaa aatctaatca cgaatgcacg gctgaacatt tatgatacat tagttatgtt
    59221 tgcagatacg ccagaaggaa ttggtcctga attagttgtg ggaaataatg tttctttagt
    59281 catccagaca agaaatgaag aagaaacgaa gcgcctattt gaaagcttag ctgagggtgg
    59341 taagattgag atgccactgg atgctgttcc gtgggctcag ttgtatggga tggtaactga
    59401 tcgatttggc atcaactggc agattaacca agagtgacag ctaaagatga atattttctg
    59461 gaaacatcaa gcagcaaacg gatcatcgtt tgtttgcttg atgtttttgt gtctatttcg
    59521 actatacggt atcttttttt tattgccaga tgcgaaaata tgttccataa tagagaagtc
    59581 cgcaaaaaat taagtaacgg aggtcagaag atgaagacgg tgatactagc tgaaaaacct
    59641 tcacaagcaa aagcctatgc cgaaaccttc caacagcaaa agcggcatga agggtattat
    59701 gaaatcagcg atccattgtt tgctggtgaa gtaaccatca cttatggttt tggacatttg
    59761 gtagatatgg ttgctccagg agcttatgaa gagcgttggg caaaatggtc tttagaaaat
    59821 ttgcctattt tcccagaaac cttccgttac gaagttccaa tggacaaacg tgcacaattt
    59881 tcgatcgtaa aacgagaatt gcagtcagcc gataccatca ttattgcaac agatggtgat
    59941 cgagaaggtg aagccatcgc gtggtcgatt attcgacaag caaacgcatt ttctaaggaa
    60001 aagaactatt tacgtttatg gatcaattct cttgaaaaag aagcaatcta tgaaggtttt
    60061 aagaatctcc aacctggaaa gaactatttt ccaaaatata aagaagcgca agcaaggcag
    60121 aacgctgatt ggctgattgg aatgaatgga agtccattat atagcttgct acttcaacga
    60181 aaagggattg atggcagttt ttctcttggt cgtgtacaaa caccgacact ctatatgatt
    60241 tatcagctgc aagaagaaat caaacacttc aaaaaagaaa cgtactttga aggagaaggt
    60301 ttaattacga caaacaaagg gcagttttct ggaaaaatcg taccaaaaaa agcatttaaa
    60361 acccaagaag agttaacgaa ggaaatagaa aaacttggag cgcatttagg taagcaaaac
    60421 ggacggattc ttgaagttac gaaaaaggaa aagaggttgc atagtccacg tttattttcg
    60481 ctatctagtt tgcagacaaa gatgaatcag ctaatgaaag caagtgccaa agctacactt
    60541 gatgctgctc aaggattgta cgaaagcaag tttctaagct atccaagaac ggattccttt
    60601 tacattacag aaaatgagca tcagtatctg gttaaacatc tgcaaaatta taaaaaattt
    60661 ttaggaatag aagaagtaca gacaactgag atcaaagcaa agaaacgata tgtcgatgcg
    60721 aaaaaagttc aagaacatca tgcaattatt ccgacaaaga cgattccgac tcctgcacgc
    60781 tttgcgaagc tttccaaatt acagcaagca atctatttgc aagttttgcg cactactgtg
    60841 gctatgtttg ctgcagatta tatctacgaa gagacgaccg taatgacggg cgtacagcaa
    60901 ttaaagctaa aaagcatcgg aaagatccca ttacagcaag gttggcagga aatcttacgc
    60961 atcaagtcaa aaaagaaaga agctcagact cttcctccta tcgtagaaaa tgaagaagca
    61021 gaagtagaac tgaaaagtat ggagaaagaa acacaacctc caaaacccta taccgaagga
    61081 acgttgatca cagcaatgaa aactgcggga aaaacgctgg ataatgatga agcgcaagaa
    61141 attctcaaag aagtagaagg aatagggaca gaagctacac gagccaatat cattgaaaat
    61201 cttaagcaga agcattacat cgaagtcaat aaaaacgaaa taactgttac gccaaaagga
    61261 atcactcttt gtaaggcagt agccaatgaa ccattactga cgagcgcaga aatgactgcg
    61321 cgctgggaag ggtacttgag aaaaattggt aaacaagagg ggacaccatc tgttttttta
    61381 gagaatatca aaaaattcat cctacattta ttggcagaag ttcctaatca aatcgacaag
    61441 gtagactttt cagatgagat tagcgggaca cgtcagataa aagcgatgga gaagaaaaac
    61501 gatcaattag gaagatgtcc aaaatgtaaa aagggaatag tcatgcttta tcctaaaatc
    61561 gctacatgct tgaatccgga atgcgacttc aaattgtggc caacagtagc taaaaagaag
    61621 ctgactaaaa cgaatctcag agatttgctt tcaaaaggaa agacaagtaa agttgtcaaa
    61681 ggttttactg gtaaaaaagg gaaattcgat gcagttttag tattaaaaga agatatgaca
    61741 atcggttttt cttttccatg gatcgaaaac agtggaacaa aagcagttga tggaaacaaa
    61801 gaaacatcaa gaaaaaataa tgaaaacgaa gtagagtaaa tgaaaacaat gaaatagcgg
    61861 aatatttatt ccgaaaagtg agaatataaa taccaataaa actaaaaaat atcagtgaat
    61921 caagcaaaaa cgttggggta ggctgatttt atatagatag caaggagttt ttttatttga
    61981 aaaaagtgca ttcattttta aattatctta tgggagcaat cacgattgtg gctgtgtacc
    62041 aagcatttct aaagtatcct gattacggga cgaagttgtt gtcattgacg cacaatcaaa
    62101 cagcatattc accaacgttg attttatcga ctttgactgc aggagctaaa agcgctactt
    62161 atttttttca taaaacgaca agcatgctaa agcgaaagaa acagcgaaaa caattgttgg
    62221 tggtggtagc ggctatgatc attatttatt ttctaccagt tattacacaa gtatttcatc
    62281 aatattttgg ttaagaatac gagagtttgt gacaaaagtc atgtcacaaa cttttttctt
    62341 tgtcattttt tcgtaagaaa aagcaaaata aaagtatata cattgattaa aagtatatac
    62401 ttggatataa tgtacttact atagaatgag aatggtatag agggtggcga aatatgaaaa
    62461 aaatgaaaaa gtataaaatt agaaaatctg gcaatagcga tgtaacaact atcccaccag
    62521 aagtaaaaga attcatgggt gtgcagacag gtgacgcaat cagttatgtt tttcaatctg
    62581 atggttctgt acgaatgatc aaagcacaag aagaacctga tattgattca ttagttgatt
    62641 cgatcatgaa tcaatatgaa gacgcgttaa aagatttggt tgatttatga ggtatctttc
    62701 gactaaagaa attatcaaaa tcaacgcgaa agttatttta ccgtcactcg ccaggcgaaa
    62761 tgatcggtgt aaaagatgca aatgcattag atatggccgt caaacagcct tcacaagcag
    62821 tattcaatca agaactctat cctgaaatct atgaaaaagc ggcgatttta gcaattaatt
    62881 tagctaaaaa acatcctttt cataatggca ataaacgaac tgctcttgtt gccatgttgt
    62941 tgtttcttca attgaataat tgtccagttg ctttttctcg tcaagaagct gttgatttta
    63001 tcataatgat taccactagt tcattggatt tcgattcact aaagtccaag ataaccagtt
    63061 atttacgaca aaccgcaata aaatgaacga attaaaaact ttatttctca attagatcag
    63121 catgtcatta aggaatatgc tgattttttt atgtttaatc atacaaaata gttttttcat
    63181 aaaaatatgg aaaatatgga ttaattttga aataattgat ttaaaaggaa tacaaaagag
    63241 tgaatagtag gaaatagtgg tttagaacta gtgggctgat tttttatata ttttagttta
    63301 cataatatat attatacaaa gtagatttaa aaaatgataa acctctctcg aacggttttt
    63361 tatcaaaaat cgtcattttt ccatcaaaat ctgcttatgc aaaattataa aaaaattttg
    63421 cagtttttct tacttttttt gtcgtttaat tgaatgataa aaaccagttt ctttattcag
    63481 ttaatcaaat atgaacgaat tagatatgaa tcattgtatt tgccgttgcg gaaggatttt
    63541 ttaattaacc acagataaac attgataacg attcgcttat tgtaatcaac agattaaatt
    63601 tcatatgttc atatgtacgg atacattttc ggaccgatta attttaacca ttctgtttat
    63661 ttgcttacct attagatatc aataaaaaac tgcttaacag ctatttcagc tgttaagcag
    63721 ttttaggatt tttagttcat attcattgtt tcttataata cagtgttcaa tacttctctt
    63781 aaagcacttg ttgatttgct gaacattgct ttttcttctt cgttgattga taattcaaca
    63841 acttcacgaa caccattttc gtcaacgatt gatggcacac ctgtaaagat atctttttcg
    63901 tcgtattcac cagttaaata agcagataca ggcaatacag cttgttcgtt attcaagata
    63961 gcttttacga tacgtgcagt actcatacca ataccatagt aagttgcttt tttacgatca
    64021 atgatctcat aagcagcatt acggacttta tcagcaatca catctaattc atcttgggca
    64081 atacgatggt ctttttctac aatttcaaac actggtttac caccgacagt tgtatgtgac
    64141 catgcagcaa cttctgaatc accatgttca cctaagatat agccgtggac gctgcgtggg
    64201 tcaactttta atttcaatgc gatttcttta cggaaacgag ttgtatccaa tgttgttcca
    64261 gtaccgataa cacgtgatgt tggcagacca gattcgttcc aagcgatata tgtcaaaata
    64321 tctactgggt ttgaagcaac aacgataata ccgtcgaatc ctgatcccat gatttctttt
    64381 acgatttggc gcatgattga cgcatttgtt ttaactaaat ctaaacgaga ttgaccaggt
    64441 ttttggttga taccagctgt gataacaacg atatcagcat ctttacattc ttcatagcca
    64501 cctgaccata cagccacatt ttcatcgccc caagccatac catctaaaag gtccaatgct
    64561 tccccttctg ctttttcttg attcacatcg atcaatacta attcattaga gattccttgg
    64621 ttgatcattg cataagcgat acttgttcca acaaaacctg taccgacgat tactacttta
    64681 cgacttgttt ttttcatgaa taaacagctc cttttcataa ctatttgtta ctttcatgaa
    64741 aagtatagtc ttgtttattc attttatcaa catgttaatt ataatagttg ttattataat
    64801 ttttgatgga aacgaattcc tgaatacgca taacagataa atgacaaatg tttacaccta
    64861 tatcccctga taatacaacc aaaagtttag aactgaaaat aaatccaaaa aaattcgctg
    64921 caacgatata ataagacagc aatcgcacct aaaacaattt tccttcatat gctttagtga
    64981 aagattttct tcttaatgtt tatttctcca ttcattggga gtacatgttg aatacttctt
    65041 gaataatttg aataaagaag tcgtttgttt atatccgata cgattagcga tttcttccaa
    65101 cgaaaaactc gtttcttgaa tcagttccaa cgcaaagtcg aattttttct ttagaaccag
    65161 ttcttgaaag gaagcatcaa aatacatttt caatttatta ctaagataga ccggattgta
    65221 gccaaaatga gctgctgttt cttttaacgt acaagaagta aaatgcttat cgatataatc
    65281 taatactcta agcatctcat tttctgcgca tccatctgct gatgaaaagc tttgttgttc
    65341 taataaatga gtcaattcga tcagtaatag tgatgtatag agatttaacg aacggatctt
    65401 atgactgtat gtatcaaaat aaatcaacag catattttca atcaaatgcg tcaaacgact
    65461 tgtttttccg ccgcgaaaat gaatgaattg tgtatgttcc cctttttctt ttgatgcatt
    65521 tatcaaaaaa gaagaaagta gattatttgt gcttgccaaa tgattcaata tctctgtaga
    65581 taaggtttct tcttttaata agatgttgat taaaatatcc tcttgccctg tgtattcgat
    65641 tctttgagta gcttctttat caatgatcac cacgtcactt tcttccatct ctatcctttc
    65701 tccattaata atttgtaaac atgtaccgct atacatataa ttgatttcaa caaaatcatg
    65761 tgtatgctcg ggaacttccg catatcgacg gtgtttactg atatgaatat ttccctgttg
    65821 aaatagatcc cctcggtgga tttttggcgg tgtctgaaga tggtaagcta agtttaaatc
    65881 attgatattc attccttgtt cacgctgcag agtttcgatt gattcttcgt tacgcaaaaa
    65941 aaatgtctaa ttcagctagt tccaattgac tccctccttt ttgtaagcgg tttctttcgc
    66001 ttattagttc acgctgtact gctattatat gcaaagctat ttttggtttc ataaagactt
    66061 tctatggttg ggacatgaac ttcctgtgat tccgctattg agagaataac cacttcatac
    66121 tatatttttg ataagcgctt acaaaaatga aaggaacatg cttatgaata aaaagatgat
    66181 gaaattttct ctgctgtcag tctctcttat tttgacttct gctggtgcag tcacgtctgc
    66241 aattcccagt atgtcagcta cttatgccac gcgttcttta tctgctgttg aattattaac
    66301 gactgctccc tcttttatgg tcactatttt tgttttgatt agtagtttta ttgctaggaa
    66361 aatcggacaa aaacaaactg tgatcatcgg attagtgatt gcatcgattt gtggtatcct
    66421 ccccctcttc tcacaaagtt acagtattgt cttagcttca agagctggac taggtattgg
    66481 ctttggattg atcaattctt tggcagtcag catgattgct gccttttatc acggagatga
    66541 acgagcctct atgattggtt ttcaaagtgc atttcaagga tttggtgcag ctttaatgac
    66601 atttgttgca ggacagctag tacagttcgg ttggcaatat acctttttag tctacgccat
    66661 cagcttacct attcttgtct tgtttgtttt gtttgttcct acacctgaaa caactgaact
    66721 tcaatcgcat ggcacagccc caacaagaca agtaatcaaa acgaatccta aaatgattag
    66781 ttatggtatt tttctcttgc tggtcatcgt ggtatataat gctgtatcga ttaaattagc
    66841 cacagtcctg acgacttatt ctctaggaaa cgaaactaat gcagcgaata tcttaacaat
    66901 catgcaattg gcaagtatgg ctgccggagt ttgttttggc tggcttcaga caaaagcaca
    66961 tcgctatatg cttacacttt ctttactact gatgggaatc ggctttgtat tgattgccac
    67021 tgtgataaac ctgtatgtga ttgggtttgg tgcgatccta acaggaattt ctttttcgtt
    67081 attcattcct tacttattca accaagtaag tatccaagcg cccaagtacg cggagagttt
    67141 caatacttca atcttattgg ttggcgctaa tttaggtact ttcattgcac catatggttt
    67201 gctctttctc tcttttgctt ctcttgggag taaaacactt gctgttttcg tcaatggcag
    67261 tatcttgctg ttgattagcg cgcttattag ccttctagta gtacacagga cgaatagaaa
    67321 gacagtgata agagtagatg aagaaataaa agaacaattg acaacaaaat aaatttgatg
    67381 gaggtcgtgt aaaatgacaa atgaaaaaca taaagataga tggctttggt atcctggaga
    67441 ctttgagatc cgccatggac tgctacaaaa tttccaacgg gaagaacgag gttttgactg
    67501 gccagcgtac tggtacatgg atgattgcca tcggaacgtc aagtttaaga gatattactt
    67561 tcttgatcaa ccttccatgt ttaaagtgac gatccaagga gttgggtatg tagaaattaa
    67621 tggacaaaaa catccatgtg gaaaatggct gacttgtcca gctggtaaag caaaaattcg
    67681 tatctttgta ggacatacat cagggctacc agcgatgttt atcgagggag acgaagtaaa
    67741 atcagatatt ggctggacag caagtaattt tattgaagaa tatccagctg gctggagtcc
    67801 gctttatgtc gatatcgcaa aagatccaaa tcaaatctat tatcaaaaag aatgcgtcca
    67861 tccagtcact gaaacggaga ttggcggagg aatcttattc gattttgggc gagcagtgaa
    67921 tggctgtgta gaactaatat ctctggatga ccatatcgaa tctatcactc tatgttatgg
    67981 agagtccgat gtagaagcta tggatatcga ttattgctac tataagcaaa taggaatgac
    68041 aagaaaaatg aaagctcgta aacgcgcttt tcgctatttg tttataccag aggtttctac
    68101 tggaatggtt caacttcaag tttttcatga atttttatct ctttcgaaac aagctgcttt
    68161 ttcaagcgat tcttctttac tgaatcagat ctggtcagta tcagaagaag ccttcaagtt
    68221 atgtagtgat ttgtttttta tcgacggtat caaacgagat cgctggattt ggtctggaga
    68281 tgcgtatcaa tcattcatga tcaatcaata tctttttttt gacgaggaaa tcaataaacg
    68341 aacgatatta gcattaagag gacaaaatga aatcaagcag catatgaata ctatcgttga
    68401 ctattcgatc ttgtggttga ttggtatcga aaaccactat atgatgacga aagactatga
    68461 atttttacgc atcgtctacc ctaagatgca atcattaatg agatacttga tggagcaaac
    68521 gaatgaatta gggtttattt atgggagagc aaaagattgg atatttattg attggtctga
    68581 aatggataaa gaaggaacgc ttgctgcaga acaagtctta ttactgaaag cctatcattc
    68641 catgatcact tgcggagata tcttagctga aacatatgga gagaacgaaa attatcatac
    68701 tcatctctat caagaaaaat atcaactatt gaaacaaaac ctatttgact acttttggga
    68761 tgaagaactt ggcgctttta tcgattgcta tgaatctggg agaagaaatg tgacgcgtca
    68821 tgcgaatatt ttcgctgttt tattcgattt tgctaacaaa gaccaacagc aatcgatctt
    68881 aaagaatgtc ttattgaatg acactatcac acagattact actccatatt tcaaattcta
    68941 tgaacaagat gctttatgca aactcggaca gacgaatatc gtctaccaaa cgattcttga
    69001 ttattgggga gggatgttat ctcatgatgc ggtaactttc tgggaagaat acgaccctac
    69061 tcaaacagga aatgaaaagt acagtatgta tggagatcct tatggaaaaa gcttatgcca
    69121 tgcatgggga gcaagcccaa tctatctttt aggacgctat tttatcggtt tgtatccaac
    69181 aaagccaggt tatgaagaat ttatgataca acctaatcta gattcatttg aaacactgaa
    69241 ttgtacgcta cctatcaaag atggaaagat ttcgcttgaa aaaacaaaag ataagatcgt
    69301 gattacttct gatagaacag gcggaacagt gaaaatgaat ggtaaaagtt atcctcttct
    69361 agcaaaacag ccacttgtct taacaagcta ttcaaaaata aatgcataaa acaaaaaact
    69421 gcttgcgaca tatcagaaga ctttaaatct tcttctgata ttgtccaagc aatttttatt
    69481 ttgaagtttg cttaattctg ttctttagaa acaatgtttg ttctttttcc ggcaaaaaga
    69541 aagctagata atacgacaag taaaaagaaa gcgatgattc caactgtcaa ggctatttga
    69601 ccgtattctc ctagtttccc aagtacaagt cctggtacta gataatcagt atcggcaaat
    69661 gtagaagaag cgattttaag atctcctaat actggaagga taaataatgg cagccaacta
    69721 atcaataagc tattgaaagc agaacctaat accgcccctc ttctaccgcc agtcgagttg
    69781 ccgaagacac cagaagcagc tccgcagaag aaatgtccta ctaccccagg aatgataact
    69841 gtagtttgca agcctatcat agcaaacatg gatagtgttc ctacaaagaa gctaacaaaa
    69901 aagccaatta atacagcatt aggtgcatat ggaaaaacga taggaacatc taatgctggt
    69961 ttagaatcgg gtacgagttt tttagcaatc ccttggaatg ctggaacgat ttctgccaac
    70021 accattcgaa ccccttgaag gacgataaca aacccagctg tgaatgttcc agcttggatc
    70081 agtgcaaaga ttacagcgtt gtctccattg cttagttctc tttcaacaaa tccaggacca
    70141 gctaacaaag caagtgcgac atatacgatc gacatcaaga gcatgatcga tacagtagaa
    70201 tctcgcaaaa agctgaaact tttaggaatc tttatgtcct ctgtagaacg gtctttgttt
    70261 ccaaaaaact ttccgatcca tccactagaa gcataaccga tatttccggt atgccctaac
    70321 gcaacttgat tgtttccagt gatgttcttc ataaacggtt gacaaagagc aggcgtaata
    70381 gttaatagtg ttccttcgaa gaccccgcct aataagatca tccacaaatt tgcagtaaac
    70441 cccgcgctta ctaaaatgac tgctgttaga caagaaacat aaagcattgc ttgacctgta
    70501 agaaaaatga atttatatct tgtgaatcta gcaagtaaaa tattcacgat catccctact
    70561 agcatgatca aagcagtagg tgtaccgtat tgttgcaaag caatcgccac tactgcttca
    70621 ttgctaggaa ctactccttg agtatgcaga gctgtttgga acatcgaagc aaaaggggtt
    70681 agtgaattac tgattaaacc agcaccgccg atcagtacta ggaatccgac aaatgttttg
    70741 atagttcctt ggatcacttc tgaaaatttc ttcttctgaa gaacgagacc aagcagtgca
    70801 atcaaagaaa cgaggatgga gggctgactg acgattgaca caaacaaatt caacaattta
    70861 tccattgata gttcctccct tgaatcattt ttattctttt gacaagatct tcgttacttt
    70921 ttcttttact tcttcgctgt caatgatcga ttgcaaaggt acgagctttt catcaggtat
    70981 agaagttagc gtatctttca aagaatgctc aatgaagaaa taatcagcca tatcgctaga
    71041 tacacttcca acatccgtat gacttacttc aaactcgtcc acatctgctc caagatctgc
    71101 aagtgcttgt ttgatgttca tctctaccat aaaacttgtt cctaatccac tttgacatac
    71161 tgcaaaaatt ttcatatcat tcgtctcctt ttcttatgat cgctaatatt tcttcttttg
    71221 ttgatgcgtg taataaatct tgaagatttt gtttattaga aagtagcttt gttaaatttg
    71281 ccaaagcccg aagatgtgcc tcattatcga tagcagctaa acagatgaac aaactaatgg
    71341 gatgggctgg attatcaagc agatccacag gttgttgaag tttcagcaaa gacatcccta
    71401 cttcgtttac gccatcttct ggacgagcat gaggtaatgc gatgtgatcg ccaatatgga
    71461 taaacgcacc atactgctcc acgcgctcga tcatagcttt gatataactt tcttctattt
    71521 tattttctga taatagcggc tgtgcggcaa atgtgattgc ttcttgccag ttttttggtt
    71581 gatccgataa ttggatcatt tcttctgtta ataattcaga tagcatagga cgttgatcct
    71641 ccttcttttc taaaagtttg ttcattttac gatttaatac ttgatagagc ttttcttcgt
    71701 ctacgccttc ttttaattcg atataaggca gtagcgccga caacaattct tgggcagaag
    71761 gcattgaaaa tcctggtatc agccaatctc tttgtacttg attgatcagc tgattttttt
    71821 ccaagtcagt catgattgga tgcagaacat agagagactt tttcttatca gtaagtgtga
    71881 gaggtacagt agaaaaaata atatcgtaag aagtttcgtc aacctcgtgt aagcggtcag
    71941 ctgaattagt ctctgtaaaa aagatcatcg ggaataattg ctgaagttca ctttttaaga
    72001 tcaatgaaga gctaatgcca cttggacaga cgatcacggc tcttattttt ctatttcttt
    72061 cttctgcgtc cgcttttctg atctctccgc caaatagtat agtgaaaaaa ccaatctctt
    72121 cttcagggat gctcttccct attcgtcttt ctaacggaag taatgctttt cttgtcattt
    72181 cgtagatgga agcatattga tgcttaattt gatcgatcat cacattaggt aaataaaaag
    72241 aataggaaat acgaaaatag gcagggacca agtgataaaa gacattcatc aataattcac
    72301 gaaacgaagc aaattctacg gccatcagga attccatgcg atggatgact tctgaagaac
    72361 attccagcaa aaaatcaagt gcaggctcct ggacatctcc ttcaacgatc gatgctaagc
    72421 aaagagagaa aaatataatc tccgaatttt gatgttcgga atagccaagg ccagtcaata
    72481 cttgtcgact aatgtcagtg actgcaagag aagccaacag ttcagcatct tttaccagtt
    72541 ccatggatgt ttttccaatt cgaatggttg tcaaactcaa ataataagct aattcatcca
    72601 ttcgatttgg tgcgaatcga agatctgata gtgaaatcgt tttatctagc aaatctctaa
    72661 ctttggcgta ataatcaatg gaaagggttg cggttaaata cgtgagccca aatcttccag
    72721 caagtgactg catcaaacga gcagtgcgat tttttgcttc tcttcttaat attgcttctg
    72781 accctagcag cctaaaacca gttttcctag tatacgacag ctgacaatct tccacttcta
    72841 attcatttct tatctttttg atatctgaca ggactgtccc tttagaaacc tgaagaaaat
    72901 cttgaaaatg aaaaacagaa acagacgttg cagtcgaata aaccatcaaa taaagaagat
    72961 ctcttcgctc ttgttcggta tacacagctt caaatcgagt aatatccaaa aatttttctg
    73021 cccagtcgat tgctcggaat ttctttatac ggatacgggt atcatccaca tattcggcaa
    73081 aaggagttaa ttgtttgatc gcctcgcttg tatttacttc gatgatctct gctgcttttt
    73141 ctagactgat ttctcttggt gttttcagga gataactaat tttgtagttc acagcgctgt
    73201 tcacctccta cttatattct agtatggtag cgcttttaaa tcgaggggtg tttggtacaa
    73261 cttacagttg gatttttttt acgactgtac cgaacgattt ctatcgaatg gatacagaaa
    73321 aaaagcaggt gaccaaatgt ctcctgcttt tatgaattga tttcgtccga tcaatgatga
    73381 tcatgtttat tttttgaggt cagttcttca aatttttctt tgacatcttc aaccgctttt
    73441 tcgatatctt tttcaaagtg attgggctca ttaggctttg tttcctcttc tacagaattt
    73501 gaaccagata aagctgtttc tttattttct gtttcaccag agtttgtgcc agctaatgat
    73561 tcttctttgt cttctgtttc accagaatta gttcctgcta aagccacttc ttcttctgtt
    73621 ttaggtgcca ttgaacctct taatcgtttg tgtttttcac cgtcataatt tgtcatgttg
    73681 gttcctccta gtagttctat actttttcat cgtacaataa gacagtttat gcgtcaaaaa
    73741 acaaacccga ttcttacaaa tatgtcatat ttttccttct gattcttgaa tgcttttgat
    73801 tccttcttcc aaaattttca tttgtaagat tgtttcttca tctttgatga ctttttctgc
    73861 gccattaact aatgtctcgt aaatcccttc gtagacacgg ctgtaatcac caacctcgga
    73921 aattactttt tcttcatgat aactcccttg ttcatctata taggtcaata caccataatg
    73981 ttcgggcaaa tcgataccaa agtcttcatg atcaggcatg taaaacattt tcagatgttc
    74041 ttcttgtcga tcttttgttt gtttcacgaa catccctttt tttccgtaaa cgacgaaact
    74101 tggacgttct ttgatgcgga aataactgga ttttatcgaa attttcatat ttccatagaa
    74161 aaaatccaga tcgaagtaat cattcattcg tcctttccct aaaagttgac gtacatcata
    74221 gctgatatca tctggttcgc cgaaataaga aagaacttga tctactgtat gacaagcatg
    74281 tccatataaa tagctgttcg cagtagaaaa ttcatgcgta ttttctggta cttccggtct
    74341 gaaataatca taatgcattt ctacttctaa aatatcccct aattttccgc tttcgattac
    74401 tttttggact gtcaagaagt cagaatcgaa ccgtctgttt tggtaacatt ggataaatag
    74461 acctttttct tttgctaatg caaataactc ttctgcttcc tttgacgttt ctgcaaaagg
    74521 tttctctact agtacattct taccatgttc gagtgccatt tttccatatt cataatgaaa
    74581 ttgactaggt gtagtgatga caactaattg gatctcagga tcatcccaaa gatcagacag
    74641 ctgatcagta tattcgatgt cttcgaatgt tttccacact ggttcagatg gggaaaaaat
    74701 ttttttgata ttgattttgt tcgtaagttt tcttgaaaaa ggcaaatgat agcgatttgt
    74761 actctttcca ttgccaagat aagcgattgt aagcatgagt ggtgcctcct tttattgatg
    74821 ttttcagtat atcctagaaa agcgcagaaa gtatttataa tagctattct ggtaaaaaag
    74881 ttcagaaaaa cacttgttat cattcggttt ggtgaaatta atgttcaaag taaggataaa
    74941 aatcaaaaag atagtagcgg aaccaagtgt ttatcagtaa gatagaattt ggaggtcaga
    75001 tcatgcttat tgaagaaaaa ctaacaaaac aagagttgtt taccacgaca gagaaacgga
    75061 ttgtcgatta catccgtagg aatatcgaag ctgcagtcta catgacgatt gaagaattag
    75121 caaaagctac gtatacttcc cattcagcta tcattcgttt atgcaaaaaa atgggattca
    75181 gcggatttaa agaattccgt ttcgagctgg ggcgggaagt tcatcaattg attgctcagt
    75241 tcaatcaaac gattgatcct aattttcctt tttcaagtga agatagcact cagcaaattg
    75301 caaagaaaat ggcggattta tcgatccagt caataaaaaa agcacaattg cagattgaac
    75361 atgaagattt agatcaaatc ggtaaagtat tgaacaaggc acagcgaatc tttctttttg
    75421 caaaaggtga ttctcaaatc acggcaagga aattccagaa taaaatggtc aagttgaata
    75481 agtttttgat catggctgaa gaatacagtg attcttcttg gaatgcagcc aatttgacta
    75541 gcgaggattg cgccattttt attagctaca gcggtcgcat ccatcattat gaacgaataa
    75601 tgacctattt gaagcatgta gaggccccta ccttgctgat taccggaaat cagcattcag
    75661 aaatggccaa acaggctgat atgtgtcttg ttatatcgca ggaggaatat gattttgcta
    75721 aagtagcgac tttctcctct caaattgcct tcgattacgt attaaatacg ttattctcag
    75781 tgatatattc tcaaaatttt gaagagaata tccgcaactt gaaaaacaaa caagaattga
    75841 tgcaaaaagg ccttcttaaa gaatatcgga aaacttaaga aaagatcctc atttagtaat
    75901 aagaaagata gtgtttgata ggctctcttt gatatcatca taaaaacagg ctgaagtttt
    75961 ctttttcaaa cctcagcctg tttgtttacg gaacgattcg aatagatata ttatagaaat
    76021 gaggaatagc taacttctgt ttcttatttt gaacgattga cgaaaaagat atataagaag
    76081 gaggaaaatc agtatacatg cagctaacaa tccatacagg aaaaatcgtt tgttctcgga
    76141 tactttctgt acttcttttt gaacttcttt tgcatgataa ggaacccggt gccctctgac
    76201 aagtaagcga tgactgttga ccatataagg tgtacaagtt aggagtgtca cgaaatcctg
    76261 ccctttttcg attctcagat cttttgtatc agtcggttct accgtcttga tctgatcgac
    76321 ttgataagcg agtgtccgtc cattgatttc gatatagaaa gaatcaccta aagtcagttt
    76381 cggtaagtct gtgaacaact ttgcttgagg cagtcctcga tggctggaaa taacggcatg
    76441 tgtattttct ccccccgtag gataagacgt tccttccaat aatgaggcac ctttttctag
    76501 cagcacagta ttcgtttcat caaaaattgg caaatggaca ttgatctcag ggatcgtcaa
    76561 aataccgatc gtatgtttct caaaataggt tctatccttt ttcgcaggtt cttttttctt
    76621 agtaaaggga tctgcacctg gatttccacc ttcttttgct aattgctggt ttttctttgt
    76681 catgttttct tggattttag ccatgacttc ttcattttct ttgaccgctt gttgctgata
    76741 atgagagatg atctgctgat ccagataatt attcagcgcg tcgctaacaa atggataagc
    76801 tagtatccct attcctgaga gaagcaagaa aagcatcagc agatctagaa gtttcctttt
    76861 ctttggtttc atttgtgttc tccttgtgat gactgtttga taataaaaga aaaaggagca
    76921 tttgcgtaat ccgctgctcc tttttccaat tcttgcaaaa agactaaatc tgactgtgct
    76981 tgcgtctagc aaagtacagt ccagcaatca gtagaaggac tactcctgca ccgatataca
    77041 catagattcc cttaccgcct gttgaaggaa gtgtaccttt gtgtttattt ggtatttttt
    77101 caggagaaat caactgtcct gctgttacat aagattgttc atcgatagta aatgctacac
    77161 ggtttgttaa tggaacatat ttttctggcg ctttcgtttc ttccagatag tacgtgccat
    77221 attttagacc tgtcacatcg attaaaccgt tacttgtggt tgtaaaaacc gttgctgatt
    77281 ctttcgccga tacccagctg acggcttttg tggatgggtc gatcgataaa tatttcgctg
    77341 tgtcactatc ttgatcacga acgacgaatt ctgctccagc aagtgtttgg tctgatgtaa
    77401 cgtcaccatc tactttaaca aatcgtttgc ccccagtaac gacatcgact gacggtggtg
    77461 tttgatcatt tgtatgcccg ttatcgacat ttgcttggtt agaaaatcct ttggttggat
    77521 ctgctttttc gttcaaatgc atatagtaaa cgaatttcaa tgtaccgcca ggagttaatg
    77581 aaggaatata attcggatca actgaaaccg tgaatccgtc tgtttgctca gtgacagaat
    77641 aatttactgg gtcgatttct ttatttccat catataaggc ataagcatac gttcctgaag
    77701 aatcattatc aaatgttaaa gcagcgtcat gagtatcgat aagtttgaat gttgtgtact
    77761 tgttttgcgt tccttcttta tcagcgatac ctaatgggat attgacagaa atctcatatt
    77821 gaattttttc accgattgcg acatcttttc cattcaattg aggtgttgtt ttaccaactt
    77881 tagacgtatc atttttgatg gtcttttcta ctggtgtttg gctatttgcc aggatctcaa
    77941 aaggcgtgat tgtttgcttt tcaatcattt ccgcattatc aggagctttt acttcttcta
    78001 aattatattt tccaacttct aaatgattaa cgatcaactg gcctttttca atagatgcct
    78061 cggcaaagtc attgttgccg atgtcataag aatgaccagt aatgaaatgt ttggctttgg
    78121 tttgatcagt tgtccaagtg tacaatccat ctgtgacact ttggatgtat tttttgacgc
    78181 ttggtgttcc ttcttcttta gaaataataa attctgctcc atttagtgct tcgttttcgg
    78241 cagtaccgat ttttgtaact ttcaacgttc catcattacc gactgtattt ttagggtaga
    78301 gatggatagt atctagttct tctgtcccgt atttataaga gccatctgct tgtttgatca
    78361 tctcatatac agggaaagct aaaaccatgt ttgcggcagc tgacactccg tcttttggtt
    78421 cttctttgat cgtgtagact gcatctttcc cattttgttt tttaggtaaa gataaagtga
    78481 catttccatc agcatctgtc gttcctgaag caactggtgt accaggagtc aaagactgga
    78541 ctgcttgttt tgctgcatcc acggacgctc ctttatctcg ttgcgcataa aattcttgag
    78601 tgacgttata aactgaaaat gaaatatcgg ctaatccttg gtattgatcg aattcgctca
    78661 tttctttccc gctgttttgg attaaaggat cgggtaaatc agtcattttc tttttatgaa
    78721 ggatgacttg agctgctgtc tcctctgcaa acactttttt tgcgccgaag ctgtttgtga
    78781 gtaatggtaa aataaggaaa aggactccta acataacgtt tattttttta tgatttttca
    78841 ttttttcact cctgttcttt ttttgataaa caaccagatt gcaaagcttg cgaataccat
    78901 accaacaacg cctaaaagtg tatttttcgt ttcgtttgtt tttggaagaa atggacggct
    78961 attttctttt ttattgacta ctttcaatat actgtccgcc tctttatcct cagaaagaaa
    79021 agttgaaatg gtaaacggaa tttctgtttc acttaaaata taaccagaag gtgcttcgat
    79081 ctcttttaat cgataacttc ctgttttcaa cccggaaatt gaaaaagcgc catttttatc
    79141 ggaaatcagg tgaagcgcat ctgattcgtt ctttgtccac ttgtatccgt tggctgtttg
    79201 ctggaggtaa tttcctgctt tgtttttaat aaggaatact gcgccagcta atcgtttatc
    79261 tggtttattt gtctcgattt tgacaaattg cttactccct gtatatacag agactttctt
    79321 tgtactgaca ccaaaaccaa aatccagtgt tccgttgttg ttgatttcct tgttcgcctg
    79381 tgctgtactg cttagctgca tctgataaga aatggtcagt ttttttccag catatttttc
    79441 caacgaaggg atcgaaaata aaacatcaaa tccgtgaggt ttcttgtgta tgacaaagcc
    79501 ttctgtcagc ttttctccat tcgatgaaat cgttaaacta ttaggtaaaa acgttaatgc
    79561 ttcatccgca ctatctgaca attcgaactt ttgatagtca aggatattta caggaattgt
    79621 cgtatgcaag gaataagtga ttttttcacc aatcgtaaaa tcatttctag gctcttctaa
    79681 taccttctca aaaggtggat cagggtagtc gttttcttca tttttaggat acaaatggat
    79741 agttgaaagt ttttgattgt tttgtccatg tacaggaaga acaactacca tattctctgc
    79801 cttttctttg acgacttctg gtactttgga ttcaatgaaa agatacgctt tatctctttt
    79861 ttcttgatct ttagcggcca gagaaaaaga agcgatacca tcttcgttgt taagagttgt
    79921 agttgttgct tctgcggtaa acataccgga agacgcaccg ttttttgcga tctctgcttg
    79981 tgcttcttct accgttttgc ccttttcccg tagatggtaa aaagaatctg tgacatcata
    80041 aacttggaat gtgacaccat ttaatcctcg atacgtttgt aataaagctt tttcttgtcc
    80101 gtcatttgga tgatttttcg gcagttgccc gtttgggaaa agcaatttgt gtaaagtaat
    80161 ctgaaccatt tctgtttctg tttctgttgc tacctgagta aaagctggtt taaatagtaa
    80221 caagaagaga cacatactaa gccaaccaag ttttttcata tttagctgcc ccctctttct
    80281 tttttcaaaa aaagatacca aatagaaaac gcacaaccaa tcatccctac tagatagatt
    80341 cctaaacggc caattcctcc cgtttcaggt aatggtactt ttgcctgatt cgtgatgtct
    80401 aaagaaatct ggttgttttt ggctcctggt gacagaacag attcatgatc ttgtccatcc
    80461 acttgaattg acccatcttc gtgtataact atagtaactg gctcttttag accttggtat
    80521 ccttctggtg taaaagtttc ggtcagcgta taagttccag gttttaaatt ttcgaataga
    80581 aaggtatctg tttcttgtcc atcttttggc gattctaagt ccatttctgg tccctgcagt
    80641 ctgaattttg ctccttttaa tgtctgtccg ttgtcttctt ttttgtgtac cgttagatca
    80701 aacgctttta gtcgattttg atgagtgagc gtccatacat tatttgtcat ctcggtattt
    80761 tttcccgtgt aaatgatttt tccatattta tcgatttgga attcataatt tcccggcgaa
    80821 gtatcatatc cggcaggacc agctgtttca acgactcgat atttaccagg tgtgagtgaa
    80881 tcaaaactgg caagaccttt ttcattcgtt gtttggctgt caattggctg ataagtacca
    80941 tttgcttctt ttttctgtag ggaaaatgct gctcctttaa gatttatctc tttgtccgtc
    81001 ccttgcatcg catacttacg tactgctaca ggaacttcaa caaaaggatt ttcaatagtc
    81061 aactggatcg tatcatcgga agtagtgact gtttttccat caatggttac cgtaccatca
    81121 gaagcgatct tgatttccca agtagtcttt ttgcttaatc catgcccttc tggagctttt
    81181 gtttctgtca gcgtataggt catttctttt tgcaatttga cattttctgg aagagaatag
    81241 gttccgtcgc catgatctgt tagtaaagta tcaatagaat ctcctgttaa tttgaaaaca
    81301 gcgccaataa gatccttttc acctgtagag gaatttttcg ttattttcaa gtttaacggt
    81361 gtgaattgtt tagtattttt ccatgtcatt gcatctattt gttgagaatc gtatcctggt
    81421 acaggtaatt ctttgattgt ttggtaactg aatgcttgac cttgattatt gtattgaggt
    81481 agtgataata tctcttgata actttctccg ctatttgcag ataatttgtc aatgtctgca
    81541 cgttcccacg tatttgttgt atctttagct ggtttaatga ttcgaatata tccgtttttc
    81601 caagctgcag catttgtcgt atgttcccgt tgaatctcaa aagtaacttg atctggacga
    81661 tcagctagat tgttgtcaaa ttcttcccat aactttttga tgtgaagact gactccggga
    81721 gctttagcag atggtatacc gaattcagct aattcattgg tatcaatgtt tggctggaaa
    81781 gttgtcctgc cgttcatttg ataccagaaa tttggatgga agtcctcatt ttctgtttgg
    81841 attctcactt ggtaatggat ttggatttct tggtcttttc ctaaatagat ctgattgctc
    81901 ttgatggtat ttccttctat ggaaatagat ggagtgaccg ttgtaggact tgtccccaca
    81961 ctcttgactg aaagtgtacc aggctgataa atgaatggtt ctgcgattgg atcatttatt
    82021 tgtccattgc ttacagttgc tgagatctgt acagcttttt tggctaggta ttcagagata
    82081 tctgttgcat gatcagctga ttcatagtaa agatcgcctt tttcatctga tgaaaccatt
    82141 tgtcgcatac gagactctac ttctgctttt gagagaccag ctgccggatc gctttgaagt
    82201 tggatgccaa gaccatgtat ttcgattcct cgttctttga gtgccatcgc ttctccgatg
    82261 gttgcgataa acgtactgtc gattcttctg gatagattgt tttggtcagg tgcatcatag
    82321 attcttgaga ttagagaagt atttcccggc cgatcttgcg tattagaaaa ctgagttccg
    82381 taataattgc tgcttgattg tgcgtgtacc cgctgtactt tataggaaaa tgttggtaca
    82441 ccatccgtca gcaaaacgat cactttttta tgtccatttg gaacggatag catgcttcct
    82501 gcatctctta gtgctttttg tgtaaaagta ccaccatttg tccgtgaagg tgtaatggat
    82561 tttacttgat ttttcactga atcaaatgaa cccatctgta ctgcaccgtt actgtagcta
    82621 tatccttcgc ttgagtagcc gacatatccc atattgattt tgtctgtgat accgctatct
    82681 gctaaagtat cgacaaaacg atcgacacca atctttactt caccgatccg attattgtcg
    82741 ttcatacttc ctgaccagtc tacgaccaat acgagatcaa gaggcgtgat atctttttgt
    82801 acatttccac gagcattcaa ataaacatca aacaatccgg gtgtacttgt ttcctttgca
    82861 tactttcgta tcgcatagtc tgcttgatta ccggttcctc catattcgat atacgaatgg
    82921 gtccgatcat taggatctcc attccaagaa tttataccat cccattgatt tgttccgttt
    82981 ttattgcctt gatgatcaag aacatttgta tttcctgtag gttgccaact ggctttagga
    83041 taagtgccct gatcatctgt tgtatattct gtaggaatcg tttgattaga tggcacactc
    83101 acagctggca aggataatgt aggcaatgta aatgggctga cagaattttc gttttctttt
    83161 gatgattctt cttctatttc gtctggcttt ggtactgaca catctgtatc tttcttattt
    83221 tctgtctcat caataatgtc atattcttta ttatcgacga tcagcttgtt tgcctggctg
    83281 tggtaaagtg ctggatcgat tggaaaactc agatcgatag tttgtttagt gtttgatgag
    83341 atttccaacg taattttccc gctatttacc tgataagcat agccatctcc ttcttttctt
    83401 tccacatcac ttaagtaatt ttcgactaga ccaatttctt tttctatctt ttcagcactg
    83461 gtgttattcg catttagctt gatgttcagt gctttttttc cagactgatc cgaaatgact
    83521 tcagctgaaa ttgtttctaa aactgttgga tcatctgtag tgtctgctat tgcagataat
    83581 ggcacaaagt ttgataaact caatattatc agcatgaaaa taactttcag tttcttccct
    83641 gtggtcgtca tttttcccct cctttttctt tttttctgtt ttgacgtgaa tagtgaaaat
    83701 tattaaaata aacaggcgtt acataatttt atttatttta atatgataat tattatacga
    83761 agggcgctaa agggaatcac accaattttc ataccaattg gtttcattta tgaagttgat
    83821 tccttcgatt aatgagcgtt tcattgaaag aaaagggttg agggagaaaa acatatgatc
    83881 aggttgttgg aaggaaacta tagaaagatg gaaaaaatca ttcgaattct gtccatttct
    83941 gacaagtgga tgactaaaaa agaacttgcc aaacgaattg gtagttcaga atctacattt
    84001 gtaaggtata tcgaagagat caaaatccgc tggggaacgg atgtaacgat tcaatcttca
    84061 caaaaattgg ggtatcgtct tgaacatttg aatgtaccag cttatttaaa tgttctgatg
    84121 gaaatgtcgc aaagttctac aaacagtcgt ttattaaatg agattattgt caatccgggt
    84181 aaaacgattg agtattattg tgaaaaaatt tccatcagcc ggtcttcttt tacacgtaag
    84241 ttgaaacaat gcaatcaaat tttagaaagc tatttattaa aagtgatcgt tgaccaaggt
    84301 tttcagttaa ctagccttaa aagtgagctc cagttgcgta tctttgttac ctttttcttt
    84361 ttaagttact acggaagacg cacgttgcca tttccaatcg aaaaaaagaa gatcaaagaa
    84421 attatggtca agaataattg tcagatgaat ttgtttcagg aagaaagccc atatgagcaa
    84481 tctttcttta ttatgtattt tgttgtgcat ctcatgagag aatcccaagg aactccattt
    84541 gaatggaaag ctggagactc ttatgtacag ttgataaata tcgataaaaa agacttctta
    84601 atcttgaaaa atctcttagg aaaattgaag tacagcagct atataaaagt agtgaactat
    84661 tttgtcaata cgattttttc agaattttcg gagaaagaaa aaaatgaaat cagtgagcag
    84721 atacgaaaaa atatgtccta ctgttcgttt tcatccgctg attgcaaaga aaaaaacgaa
    84781 gaatatgttg ttcaattatt aacgcaaatt tattttttct cccgtatttt cccatacgat
    84841 acgactcatt tgacgatccg tgcaacttac tttgcacagc agatgcaaca ccgccagata
    84901 cgtctatatg ctggatttcg tgcagaactt caattttatt ccactctact gaatcagaat
    84961 ctgatttatt atttatctag ctatatcttt tggatgctta tcggtaatcc tgaaattcac
    85021 cattatactt ctgataaaaa aatactgatt atcagcgact taagtcttcg acatagtcaa
    85081 tatattgaag aatatatcag tgatattctt gctgtgcata aaattcactc tgagacaact
    85141 gctattactg aagatcagct gtcgaaatac aatcttctcg agtatgatct gatcgttacg
    85201 aatcaaccca ttttgaatgc ccatgttcct catatattga ttgatgatag tgtgtcattc
    85261 gcaaatgaag aagaactcat ccgcttattc gagttatgaa taatcaaaaa acagctatgt
    85321 ataaaccacc ctgataaaaa tttcaggaca aata
//
LOCUS       DAPBAF010000005        78991 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.005, whole genome shotgun sequence.
ACCESSION   DAPBAF010000005 DAPBAF010000000
VERSION     DAPBAF010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 78991)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 78991)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..78991
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.005"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            432..3239
                     /locus_tag="RD451_000391"
     CDS             432..3239
                     /locus_tag="RD451_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDT7565685.1"
                     /translation="MYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNSSKDLNQLVR
                     EGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDTKDIFAKIIG
                     ANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAHHVIDEETEL
                     IVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLDEIHRLPPEG
                     QEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRIPINIKLPAF
                     EKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQLKSNIQLVCA
                     RGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKITVAPNDTIMK
                     IQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFYKDHGFSFNA
                     DSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKKINLGEERHT
                     NDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLRANQASGRIG
                     VVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNVQEVDEGSGV
                     ILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDLDMLHESLKN
                     FRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNKRQETELEVL
                     ALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVILDQLLMESE
                     LEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTTGIGDEEYGF
                     KINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLEDQIKVKVPIE
                     EMYYLLRLVHNQLDKKEYTVP"
     gene            3430..3921
                     /locus_tag="RD451_000392"
     CDS             3430..3921
                     /locus_tag="RD451_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDT7565686.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            4024..5013
                     /gene="manX"
                     /locus_tag="RD451_000393"
     CDS             4024..5013
                     /gene="manX"
                     /locus_tag="RD451_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HDT7565687.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            5046..5849
                     /locus_tag="RD451_000394"
     CDS             5046..5849
                     /locus_tag="RD451_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HDT7565688.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            5870..6784
                     /locus_tag="RD451_000395"
     CDS             5870..6784
                     /locus_tag="RD451_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HDT7565689.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVERWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            6867..7241
                     /locus_tag="RD451_000396"
     CDS             6867..7241
                     /locus_tag="RD451_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HDT7565690.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGDNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            7380..7625
                     /locus_tag="RD451_000397"
     CDS             7380..7625
                     /locus_tag="RD451_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HDT7565691.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            7797..8861
                     /locus_tag="RD451_000398"
     CDS             7797..8861
                     /locus_tag="RD451_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HDT7565692.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            9107..9532
                     /locus_tag="RD451_000399"
     CDS             9107..9532
                     /locus_tag="RD451_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HDT7565693.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            9525..9974
                     /gene="nusB"
                     /locus_tag="RD451_000400"
     CDS             9525..9974
                     /gene="nusB"
                     /locus_tag="RD451_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HDT7565694.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            10071..10925
                     /locus_tag="RD451_000401"
     CDS             10071..10925
                     /locus_tag="RD451_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HDT7565695.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            10926..12263
                     /locus_tag="RD451_000402"
     CDS             10926..12263
                     /locus_tag="RD451_000402"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HDT7565696.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            12268..12492
                     /locus_tag="RD451_000403"
     CDS             12268..12492
                     /locus_tag="RD451_000403"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HDT7565697.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            12494..13384
                     /locus_tag="RD451_000404"
     CDS             12494..13384
                     /locus_tag="RD451_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HDT7565698.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            13393..14211
                     /locus_tag="RD451_000405"
     CDS             13393..14211
                     /locus_tag="RD451_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HDT7565699.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            14318..14767
                     /locus_tag="RD451_000406"
     CDS             14318..14767
                     /locus_tag="RD451_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HDT7565700.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            14785..16467
                     /gene="recN"
                     /locus_tag="RD451_000407"
     CDS             14785..16467
                     /gene="recN"
                     /locus_tag="RD451_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HDT7565701.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(16522..16638)
                     /locus_tag="RD451_000408"
     CDS             complement(16522..16638)
                     /locus_tag="RD451_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HDT7565702.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(16711..17667)
                     /locus_tag="RD451_000409"
     CDS             complement(16711..17667)
                     /locus_tag="RD451_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HDT7565703.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            17838..18206
                     /locus_tag="RD451_000410"
     CDS             17838..18206
                     /locus_tag="RD451_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HDT7565704.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            18376..18807
                     /gene="mraZ"
                     /locus_tag="RD451_000411"
     CDS             18376..18807
                     /gene="mraZ"
                     /locus_tag="RD451_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HDT7565705.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            18828..19787
                     /gene="rsmH"
                     /locus_tag="RD451_000412"
     CDS             18828..19787
                     /gene="rsmH"
                     /locus_tag="RD451_000412"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HDT7565706.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            19792..20193
                     /gene="ftsL"
                     /locus_tag="RD451_000413"
     CDS             19792..20193
                     /gene="ftsL"
                     /locus_tag="RD451_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HDT7565707.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            20194..22386
                     /locus_tag="RD451_000414"
     CDS             20194..22386
                     /locus_tag="RD451_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HDT7565708.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSAYGVYSVPGYNVSAKNGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            22412..23374
                     /locus_tag="RD451_000415"
     CDS             22412..23374
                     /locus_tag="RD451_000415"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HDT7565709.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            23388..24749
                     /locus_tag="RD451_000416"
     CDS             23388..24749
                     /locus_tag="RD451_000416"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HDT7565710.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            24775..25863
                     /gene="murG"
                     /locus_tag="RD451_000417"
     CDS             24775..25863
                     /gene="murG"
                     /locus_tag="RD451_000417"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HDT7565711.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            25878..27098
                     /locus_tag="RD451_000418"
     CDS             25878..27098
                     /locus_tag="RD451_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HDT7565712.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            27254..28579
                     /gene="ftsA"
                     /locus_tag="RD451_000419"
     CDS             27254..28579
                     /gene="ftsA"
                     /locus_tag="RD451_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HDT7565713.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            28602..29843
                     /gene="ftsZ"
                     /locus_tag="RD451_000420"
     CDS             28602..29843
                     /gene="ftsZ"
                     /locus_tag="RD451_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HDT7565714.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            29860..30537
                     /locus_tag="RD451_000421"
     CDS             29860..30537
                     /locus_tag="RD451_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HDT7565715.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            30551..31150
                     /locus_tag="RD451_000422"
     CDS             30551..31150
                     /locus_tag="RD451_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HDT7565716.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            31165..31452
                     /locus_tag="RD451_000423"
     CDS             31165..31452
                     /locus_tag="RD451_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HDT7565717.1"
                     /translation="MYTIALLLHLLQRAAYFYSIILMVYALLSWFPGGYQSGLGRLLA
                     KICEPYISLFDRLPLRIGPLDFTILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            31501..32283
                     /locus_tag="RD451_000424"
     CDS             31501..32283
                     /locus_tag="RD451_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HDT7565718.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            32304..33011
                     /locus_tag="RD451_000425"
     CDS             32304..33011
                     /locus_tag="RD451_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HDT7565719.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            33273..36071
                     /gene="ileS"
                     /locus_tag="RD451_000426"
     CDS             33273..36071
                     /gene="ileS"
                     /locus_tag="RD451_000426"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HDT7565720.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKGYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(36120..37646)
                     /locus_tag="RD451_000427"
     CDS             complement(36120..37646)
                     /locus_tag="RD451_000427"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HDT7565721.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(37661..38308)
                     /locus_tag="RD451_000428"
     CDS             complement(37661..38308)
                     /locus_tag="RD451_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HDT7565722.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(38492..38821)
                     /locus_tag="RD451_000429"
     CDS             complement(38492..38821)
                     /locus_tag="RD451_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HDT7565723.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            38998..39726
                     /gene="sfsA"
                     /locus_tag="RD451_000430"
     CDS             38998..39726
                     /gene="sfsA"
                     /locus_tag="RD451_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HDT7565724.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            39742..40755
                     /locus_tag="RD451_000431"
     CDS             39742..40755
                     /locus_tag="RD451_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDT7565725.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            40755..42032
                     /locus_tag="RD451_000432"
     CDS             40755..42032
                     /locus_tag="RD451_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDT7565726.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            42095..44797
                     /locus_tag="RD451_000433"
     CDS             42095..44797
                     /locus_tag="RD451_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDT7565727.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            44949..45266
                     /locus_tag="RD451_000434"
     CDS             44949..45266
                     /locus_tag="RD451_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDT7565728.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            45296..45616
                     /locus_tag="RD451_000435"
     CDS             45296..45616
                     /locus_tag="RD451_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDT7565729.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            45724..47184
                     /locus_tag="RD451_000436"
     CDS             45724..47184
                     /locus_tag="RD451_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDT7565730.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGTLPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGPNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            47252..47473
                     /locus_tag="RD451_000437"
     CDS             47252..47473
                     /locus_tag="RD451_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565731.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            47504..47686
                     /locus_tag="RD451_000438"
     CDS             47504..47686
                     /locus_tag="RD451_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HDT7565732.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            47686..48099
                     /locus_tag="RD451_000439"
     CDS             47686..48099
                     /locus_tag="RD451_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HDT7565733.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            48222..49403
                     /locus_tag="RD451_000440"
     CDS             48222..49403
                     /locus_tag="RD451_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7565734.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            complement(49474..49638)
                     /locus_tag="RD451_000441"
     CDS             complement(49474..49638)
                     /locus_tag="RD451_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565735.1"
                     /translation="MNDKPKEKVYAERLDSSKKNREKITKEAIQDHKKENPKTKENKK
                     FKFTKKEDLL"
     gene            49792..49865
                     /locus_tag="RD451_000442"
     tRNA            49792..49865
                     /locus_tag="RD451_000442"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:49826..49828,aa:Arg,seq:cct)
     gene            complement(49934..51073)
                     /locus_tag="RD451_000443"
     CDS             complement(49934..51073)
                     /locus_tag="RD451_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDT7565736.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDID
                     FEDQIITINKTWNYKLNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEIK
                     NPHNFVFFNLKNGLVSSNAVSKYLRKKLKELGIEKQFTLHGLRHTHASILLYQGVNIL
                     SVSKRLGHSSLETTMSTYLHIVRELEDQDKEKINTVFDSLYKNDN"
     gene            complement(51372..52007)
                     /locus_tag="RD451_000444"
     CDS             complement(51372..52007)
                     /locus_tag="RD451_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565737.1"
                     /translation="MDNSNEKLTKKEYLELIVEGGIGAIPYIGGVVQSLYFGSKNEKR
                     FKRIEKFYKNLNESLENIRDQIPEDVFNLENKDQLIGIFEGINDEVEKSKAQNKIDMY
                     KNLYKNCLLRINSASWDNEEYYLLVLNQLTSIEIQLLACLMSRGNENFTGNISMSGYS
                     QELIDGSLNRLSDFGLLEKTISSIVLGDVGKQNMGYKISHLGIQFINSTLT"
     gene            complement(52120..52755)
                     /locus_tag="RD451_000445"
     CDS             complement(52120..52755)
                     /locus_tag="RD451_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3221 domain-containing protein"
                     /protein_id="HDT7565738.1"
                     /translation="MDGIFGFTGIVLFIIGLIMLIVRFIKKTNKKTPMILLIIGIIFT
                     TVGFSLSSSNEANDNNKQESSSSDTQTTTSNSSNKSLTQFEEFLETNNHDWGAFLDSY
                     YSITPATEQNTAFTKYISGKTYTFEGTVIESMTTRIAIIADKEYDDKSWNDISATPKV
                     SYVIFAKDLNNADTFTKGDKVTFTGEISSRGSNIEKSYAQWDMINSKVSKK"
     gene            complement(52789..53250)
                     /locus_tag="RD451_000446"
     CDS             complement(52789..53250)
                     /locus_tag="RD451_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HDT7565739.1"
                     /translation="MEKEILIKSPGKTLIKVTDDSISIIRKGFINLVNQGIKGEKTIP
                     FKNISAVQLKKPGMSNGYIQFTLLGGNESRGGILAATKDENTVMFTKKYWNEMENLKK
                     YIEKQQSILDNNSKETQISSADEIKKYKELLDEGIINQEEFDFKKKELLGL"
     gene            complement(53380..53811)
                     /locus_tag="RD451_000447"
     CDS             complement(53380..53811)
                     /locus_tag="RD451_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HDT7565740.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFSASHFEFSVLYDTSTTFHSKFETEADKIAILILLNIYIENELTDE
                     SQFNLEKFMEYYSIQNKLRYTCYAVCQCYFKKKYSYARQYV"
     gene            complement(53829..54149)
                     /locus_tag="RD451_000448"
     CDS             complement(53829..54149)
                     /locus_tag="RD451_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7565741.1"
                     /translation="MNTYEIIKDLAKRKKISIRQLEINFGYSNGYLAKWKNNTPNSDE
                     LSRIADYFDVSVDYLLGREERETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            54448..55224
                     /locus_tag="RD451_000449"
     CDS             54448..55224
                     /locus_tag="RD451_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HDT7565742.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVASVLGYSNTKDALS
                     RHVDLEDKMGSRITTSGQSREMTIINESGLYSLILKSKLPSAKKFKRWVTSEVLPAIR
                     KHGGYLTPEKVEEALLNPDTIIQLATQLKEERTGRLIAEQKIAEYEPKISYLDSILSS
                     TDSVTISQIAADYGMSPQQMNKLLHKLGIQKKVGNQWLLCKKHMNQGYTKSHTTEIPK
                     ADGGTKIVMNTKWTQKGRLFIYELLKKEGYYPQMDLEEIG"
     gene            55239..55442
                     /locus_tag="RD451_000450"
     CDS             55239..55442
                     /locus_tag="RD451_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7565743.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            55458..55796
                     /locus_tag="RD451_000451"
     CDS             55458..55796
                     /locus_tag="RD451_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HDT7565744.1"
                     /translation="MQYLEAKIPIPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRRQADGKI"
     gene            55783..55962
                     /locus_tag="RD451_000452"
     CDS             55783..55962
                     /locus_tag="RD451_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565745.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEAEYRAKKPTEGAD"
     gene            complement(56005..56475)
                     /locus_tag="RD451_000453"
     CDS             complement(56005..56475)
                     /locus_tag="RD451_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565746.1"
                     /translation="MSIISFILSTFLTGIKIKGMRPQLEVELNASYFAADMIYTKVII
                     SNYSTEPAMLVNLELSSANLNRRWSATPFKKLIAKGGSVDDNRIYSEAVPLNIPPKSA
                     ISCYLAFEVGKINFNKLLNHQTKMIFTLNRTQIHKIVDIKNTNFPIEKLVKELN"
     gene            56562..57260
                     /locus_tag="RD451_000454"
     CDS             56562..57260
                     /locus_tag="RD451_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HDT7565747.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNMKVMGVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDDNE"
     gene            57438..57779
                     /locus_tag="RD451_000455"
     CDS             57438..57779
                     /locus_tag="RD451_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565748.1"
                     /translation="MEKELSTLDQYLIDPDWGKPKIEETSGRKIRRNLLTNEELAWDQ
                     DDLGNHVTIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEEYDRDNLIDISYYGPGKK
                     YIAEMEAEFDE"
     gene            57772..58443
                     /locus_tag="RD451_000456"
     CDS             57772..58443
                     /locus_tag="RD451_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HDT7565749.1"
                     /translation="MSEIKGTTNFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
     gene            58449..59135
                     /locus_tag="RD451_000457"
     CDS             58449..59135
                     /locus_tag="RD451_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565750.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDISATINEEVNIDRLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHAEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     KTIKKLNIGG"
     gene            59138..59887
                     /locus_tag="RD451_000458"
     CDS             59138..59887
                     /locus_tag="RD451_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7565751.1"
                     /translation="MTEHRSYYAIIPANVRYDKRLKPNTKLLYGEITALCNERGFCWA
                     GNEYFADLYGVNKETISRWVSDLIKFGYLNREIIYKEGTNQIINRYLRINQYPIDEKR
                     NTPIDEKVKDNNTSINNTFNNTKEYIRELPPSKKSKAKPVRHKYGEYKNVLLSDEQME
                     KLKTEFPNDYQERIERLSEYCESSGKTYKNYLATIRSWARKEKSEPKNASSGYKRTGR
                     REKLPEWAIDQEAYLKKKALERANRQSKAPF"
     gene            59899..60168
                     /locus_tag="RD451_000459"
     CDS             59899..60168
                     /locus_tag="RD451_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565752.1"
                     /translation="MKIDYLELINEIANYKKGEELDVLRDVYDQLEEAGIEGIKNDRS
                     SWSKLRYYFALYIDGTQLRNLAYTKLLFIDCVKGLQKHLNELEQV"
     gene            60174..60338
                     /locus_tag="RD451_000460"
     CDS             60174..60338
                     /locus_tag="RD451_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565753.1"
                     /translation="MDLKTFTAQIELMHQEALRQSVSYEDKWLNTFHGGRESALDQVL
                     KLLKGECRDG"
     gene            60331..60629
                     /locus_tag="RD451_000461"
                     /pseudo
     CDS             60331..60629
                     /locus_tag="RD451_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301507.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            60629..60931
                     /locus_tag="RD451_000462"
     CDS             60629..60931
                     /locus_tag="RD451_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HDT7565754.1"
                     /translation="MDELIAKVEQWAKDKGLDQADFSKQMLKTVEEIGEVAASLARKD
                     EHGLRDGIGDVVVTLIILAMQNDMDLYECLDFAYDEIKGRTGKMVNGVFVKSSDLK"
     gene            60971..61336
                     /locus_tag="RD451_000463"
     CDS             60971..61336
                     /locus_tag="RD451_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565755.1"
                     /translation="MIDAKQVQKQKDGMLMFEAYVLPFLNQFEVLECSASGEELEYVV
                     IRETKENVQKLNEFLCTINCWDMIAPGFLCPAMGEFLEYCRLEDAGTLDLAYLVYNYL
                     NINTDHLWFGTAERKWVVR"
     gene            61826..61966
                     /locus_tag="RD451_000464"
     CDS             61826..61966
                     /locus_tag="RD451_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565756.1"
                     /translation="MNEIAADHELSETALIDQIELARQYFVPYADTWSKHKNDIIFPE
                     EQ"
     gene            61963..62151
                     /locus_tag="RD451_000465"
     CDS             61963..62151
                     /locus_tag="RD451_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565757.1"
                     /translation="MRATDPVIILEEAKFIWTHEEIEQARLLFSQGVKPSKVAEIMGQ
                     KILDVGLLLLHLAEKNLI"
     gene            62159..62353
                     /locus_tag="RD451_000466"
     CDS             62159..62353
                     /locus_tag="RD451_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565758.1"
                     /translation="MMIQLAGIQTGKIYFSGESKSEANQWLLKTYTNNKKLRKKYPDL
                     LLKDDQIMPEPMILTRKEGS"
     gene            complement(62386..62598)
                     /locus_tag="RD451_000467"
     CDS             complement(62386..62598)
                     /locus_tag="RD451_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565759.1"
                     /translation="MNINNLVKLVEQRFKESGLEQLKKDNSPELFSNFTEDDIPTLKQ
                     LKYYSDYWTQTRENELNLEKLIIKKK"
     gene            62723..62926
                     /locus_tag="RD451_000468"
     CDS             62723..62926
                     /locus_tag="RD451_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565760.1"
                     /translation="MVKVREQFKIVSDEDNVYKIKIVNINEYREADHKYLVDLYMNDK
                     YLGEGFCGDSLFDDERILKEETE"
     gene            62923..63195
                     /locus_tag="RD451_000469"
     CDS             62923..63195
                     /locus_tag="RD451_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3850 domain-containing protein"
                     /protein_id="HDT7565761.1"
                     /translation="MIHELKILPEYFEAVTSGRKQFEIRKNDRDFKVGDQLILREYKK
                     YIKHELPGLTRPTFSYTGDSYKAEITYITDYMQKSGYVVLGIKGVN"
     gene            63196..63381
                     /locus_tag="RD451_000470"
     CDS             63196..63381
                     /locus_tag="RD451_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565762.1"
                     /translation="MKVYILAITEGTWMFPVGSGKIYKSKTAAYKAFEKYKKENGGGT
                     NAKILVADNWHEEGERN"
     gene            63368..63715
                     /locus_tag="RD451_000471"
     CDS             63368..63715
                     /locus_tag="RD451_000471"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565763.1"
                     /translation="MNVIDLPVHFRGTNYFYASNLIQKKMSKDERKILANFYLVLKIE
                     QNVFSERRIVWEKQNQRLRRKNDVWNKRQSRMERLRKNKKATPFEIAAQYYSTIRGGV
                     CEISLVKRLPRTR"
     gene            63675..64151
                     /locus_tag="RD451_000472"
     CDS             63675..64151
                     /locus_tag="RD451_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HDT7565764.1"
                     /translation="MRFHWLKDYQELDEQILYLKWNLNKSKLELNRWVCGDLANVRIE
                     KNSRTSSLEENIQKIENELELLIEQKEEMLLLIDSFSGIDNQIVKMKYVDQMSLEDIA
                     ESVGYSSSYVRQRHAEIRKTLNFLDEYEHRQADRLKKENEIDFYNSEKYKEQLSLF"
     gene            complement(64297..65025)
                     /locus_tag="RD451_000473"
     CDS             complement(64297..65025)
                     /locus_tag="RD451_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4145 domain-containing protein"
                     /protein_id="HDT7565765.1"
                     /translation="MRGVLMLQEVNIKYRDRQNTETIYLPNSCPHCGNIMTPYVYFGV
                     SSYSAFDNDRIFGVLVQCINDECNKFYSLQFINTFNEDEGYSENILIKDYYRPPIKID
                     LPENIEKVSPTFVDIYTQATQAKSEQLEQIAGVGYRKALEFLIKDYAISKNSEDEDKI
                     KKMLLGKTIENYLNDFPKLQRLAKAATWIGNDETHYVRRHTNKDVHDMDAFIKSAAQF
                     IAADYDADLADQFINGNNFMPTTN"
     gene            65073..65351
                     /locus_tag="RD451_000474"
     CDS             65073..65351
                     /locus_tag="RD451_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565766.1"
                     /translation="MNDFHEAVLSIEVESSLAKVYKKAIEAENSPYRENWNGNHAHVQ
                     VENDDYRTGMNTLVISLLSHTLPNLQETIEWYERMGAKVIRTNYKGEN"
     gene            65353..65739
                     /locus_tag="RD451_000475"
     CDS             65353..65739
                     /locus_tag="RD451_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565767.1"
                     /translation="MAMIKIRTSISGTEYWDSEKKRTVVVPKDQEPNFEVKEEKGILS
                     DGKSFVAVNGELIAHSSEILDSDGNTAANFDGDEATNDQSTEDTDELDNMTAKELRAY
                     AKKHGIDIPGAIRAKGDIINLIREVE"
     gene            65736..66116
                     /locus_tag="RD451_000476"
     CDS             65736..66116
                     /locus_tag="RD451_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HDT7565768.1"
                     /translation="MKYCQFDGCTNKIAKGIYCTEHKRSSRSRKKKQQAKSVYHHENK
                     PFYRTQAWKDMRQFIYEREGGHCQRCGQFIFGKRAHVHHIVPIKDNELLKLDPNNLML
                     LCSKCHPIVENETEDKKVFPSYFN"
     gene            66228..66680
                     /locus_tag="RD451_000477"
     CDS             66228..66680
                     /locus_tag="RD451_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HDT7565769.1"
                     /translation="MTTKAQRKAIIDEKVSAEKARILEIMNLSDLYTITLDPLIESYL
                     DIFEIYQHKYLLWKEKGFPETQKFTNKSGATNQSKHPLAQQVETWADKKMKALDLLGL
                     TNKAKTGRLIAGGSTARKDEEITRPEVKPVDELAAHRNKWRKKAGAEK"
     gene            66677..68404
                     /locus_tag="RD451_000478"
     CDS             66677..68404
                     /locus_tag="RD451_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HDT7565770.1"
                     /translation="MIEPGVNYADLFAKEVRKKPKKYPKTVRLAIDRWYQWKKRKDIW
                     FDVDRANEMMDWVESFIVHTKGEMVGKPFLLEPWEKFIYSWIYGWVKENEKGQIVRVT
                     REAYVQIPKKNGKTLIAVGSLGYAMYGEGALSVDCYACASDFAQAQYAAKPFAVTILN
                     NPILLEGTKIFRGPKGTVSSITYDYIHEDMAYSNKFIVQTKNIDNIEGSNPYFVLNDE
                     LHKQEKMEQYDNFKSAQISLPQPLMFNISTAGKGSSSVGMRVYREAKEVLKRDDNDSN
                     FVLIYEPNKNYDWTDRKVWEMCNPNWGISVDLSALESAFKTAQRSAHSKAEFLTKHLD
                     VFVNGADNFFEQDQVEPCLVTTQELGDLSGEPCYIGLDLSRTRDLTCVSLNFPTWDED
                     GKAVLKVKQLYFIPNEDLEFREKEDNVPYSDLAEQGFVEFCDGKMIDQDQILQYIEDC
                     MNLYDIQQVNYDPAMSDKLVEKLENLGLECVEVAQYPKVLNAPFDDVERLFYEKRIQF
                     DNPLFLYCTLNVVAITNINGQKAPSKRQSKKKIDGFVAFLCGHKETMNQMTDIDSDEL
                     DDYLSSIYR"
     gene            68468..69655
                     /locus_tag="RD451_000479"
     CDS             68468..69655
                     /locus_tag="RD451_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDT7565771.1"
                     /translation="MEKRGYIEDIFGHYTRYGQRYVTDSSIMESSDVYELVQDISNQV
                     ALATPIVIGPDGNEVKDHHLLNILKSPNDYLTGFEFTKLETNTLLINGETFPLTDRDQ
                     LHLAYGVTTKINERLQEEFEMNGQKIPGQMIRHIKNIGTDSLKGAGIIDLARNTLEGV
                     LSAEKVLTDKYTKGGLLAFMLKLDAHINPNNSAQTKIVKAILDQLEGTQNESDHSVKM
                     IPLGKGYSIETLKSPVDDAAILNYLGVYKKDLGKFLGINVDTYQSLMKTDIEKAMMYL
                     HNKAIKPILKNKSEHYTALFFMPNSGYRVEWKINILDFVPYSTKTNIGYNIVRTGITS
                     PDNVAEMLGFPKQNTPETQAIYISNDLSRIGQKNATDDSLPTNDQDLKGGDGNEEEGN
                     SHD"
     gene            69627..70196
                     /locus_tag="RD451_000480"
     CDS             69627..70196
                     /locus_tag="RD451_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HDT7565772.1"
                     /translation="MKKKEIRTIDITNLSTRSDEETHTRTISGYAAVFNSQTLLWDDL
                     SEVIVPGAFSKAISNSDVRCLFNHDWSNVLGRTKSGTLRLEEDERGLKFEVDLPDTTV
                     ARDLVKSMERGDINQCSFGFVPTEETWDYNSEPMLRTIHEVELYEVSIVPLPAYEDTE
                     AALRSRDELEKNVEERKKLIKKINQALEA"
     gene            70209..71573
                     /locus_tag="RD451_000481"
     CDS             70209..71573
                     /locus_tag="RD451_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016622740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HDT7565773.1"
                     /translation="MDKELLKKMKARREQRLTELREKVESGELREADLEAVKEEIDSV
                     IDELNGIKDELGADSGTDETDDNTDDQSNSTDSDESRSGEDNDQEEDSDSEDSSENRS
                     GMITQQQRDGLLGSIKNGLEARAKMTKKQKDQQLRKAFANFVAGNISEAEARALGIEA
                     GNGSVTVPEVIASEVITYAQEENLLRKYGTVVRTSGDVKYPILVKKADANVNKKERST
                     DIAETAIQFDEILLNPAEFDALATVTKKLLKMSGVPVEDIVVEELKKAYVRKEINYMF
                     NGDDAGNENPGALAKKAVAFKKPLDLTASGAGQKLYDALIEFKNTPVTEVMKKGRFII
                     NRAALTAIEKMKTDDGFPLLRPFTQAEGGIGYQLVGYPVDWTDAADKKGEPDTPVLYF
                     GDFSAFKIQEVIGALEIQKLVEKFSGKNQIGFQIYNLLDGQLVYSPFEPAVYRYEITK
                     PVGG"
     gene            71575..71856
                     /locus_tag="RD451_000482"
     CDS             71575..71856
                     /locus_tag="RD451_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002395304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HDT7565774.1"
                     /translation="MEEQTKELSLEEKFKSHIHFEEGMDDSLLSFYLNMAKDYVKTAT
                     GGQQEYLILMVAGIAYEYRVSEDELDKAMNAMTPFIVQGAIQNAEETDQ"
     gene            71834..72160
                     /locus_tag="RD451_000483"
     CDS             71834..72160
                     /locus_tag="RD451_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HDT7565775.1"
                     /translation="MPKRQTNNLRWKAELLDIKTGTDGNDRPTTIYEFKRLIFYEELG
                     VTSQEKYLSQQAKTDVVRRIKVRWDKSITEKLSALKIDSVTYNITRIYTNPDAREMEL
                     SLAYVD"
     gene            72150..72488
                     /locus_tag="RD451_000484"
     CDS             72150..72488
                     /locus_tag="RD451_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565776.1"
                     /translation="MSISFDELKTALKSTKLAVFRDKARLGTMYPYIVYSNVSNSKKM
                     ASGKVYKKLPYYQVSFFTLGTEQDLVVIEQALQNAGIPYSDFTGIQGDENDDTVTNYY
                     TYVRCVENAK"
     gene            72478..72843
                     /locus_tag="RD451_000485"
     CDS             72478..72843
                     /locus_tag="RD451_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HDT7565777.1"
                     /translation="MPSNKNGFSEISDYLGNLSKVDPKKLSLESLEEAANFYLKQLLP
                     NIPKSLLKKKHMRDQIKVVVENDQVKVQFEETAFYWRFAENGTTNQRAQHFASGTYEQ
                     NKEKIEEIMTRKILDLWEG"
     gene            72850..73476
                     /locus_tag="RD451_000486"
     CDS             72850..73476
                     /locus_tag="RD451_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDT7565778.1"
                     /translation="MGKQDTFYFEGLDDILIAMMATPDSVGTAPTYSEVLRLPIATKI
                     GVKGNGTALEKWASSKMFRRVSRETKHELALDHVGIPIEVMDEIKGLVAKSGVTFSKN
                     TAREFPYFAFGFIGNIENGGKKAVWYPNTQLSNVIDEEYATAEEETKIDDVTANLVSI
                     GLKYNNVMYASFDSNRDGASLELFNKFIAQPVYDEEQWKTLAKVGGAG"
     gene            73476..73940
                     /locus_tag="RD451_000487"
     CDS             73476..73940
                     /locus_tag="RD451_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565779.1"
                     /translation="MARLSDYGIHVEDLKNSAVVIIQGAEFPISFTMQTMEFIADVYG
                     GDYSQFESDMNAMLSKKEGQISSANLSPSDLKIMRALIYAMLRTGGLEEDPETIFKFL
                     GMSGEVLSAYSTCMEIFASQTFQVEDLKKSKKPQDFQKAQAKRKKNKKNRKR"
     gene            74135..76444
                     /locus_tag="RD451_000488"
     CDS             74135..76444
                     /locus_tag="RD451_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HDT7565780.1"
                     /translation="MAGKESDVVLNFKTNGEVSYSKTIKEINKEMNLAAAEYKNQVSA
                     MDKDATQTEKLRAAKQKLEKQLGLAEQRSQMLREEYEKSVKETGEYSAESEKLYKQLL
                     NSETGENKLRTALEQTNDALKEQGDVSVDTAKKLQKIEETGEKVKGVGEKMSVGVTAP
                     IVAAGAAGLAAFGEVDEALDTIITKTGATGDQADRLSQSFKNVGSNTHLPLQTVGEAI
                     GEVNTQFGFMDKKLEDSTNYLLQYAEINDTDVSQSAISARQAIDAYGLEYDDLNSVLD
                     VTTKTSQNTGQSVDDLMQKAIDGAPQIKQLGLSFGEGVTLLGQFEQSGVDSSAALSSL
                     SKATVAYAKDGKSLSQGLEELQDKVKNAGSETEAINAAAEVFGTKGGPRMADAIRRGT
                     LNLEDLAKTAGESGGAVGDTFDATLDPIDQADQAMNNAKLAMADVGEAVQVSLLPFFE
                     KATSLLQEFSKWWGSLDQDTKNWIITIAGIAAAVGPVLIVLGSLMGSVTKIVGEVKSF
                     IGVWQGLAGLFGMSGGWFALAVIAIGALVTGLIWAYNNVKWFHDGVNSFFKGVSDVAV
                     EIFNFLSGYFGGFFDGVIANFNNFYNAGKRIFSGFLDFITGVFTGNWSKAWQGLVDIF
                     GGIFDGIVAVGKAPINAMIGLINGFIGGLNNIKIPKWVPGVGGKSFSISKLPYLAQGG
                     HLINGQAIVGEAGPELLTAKNGKTTVTPLSDEEKRKGISGRVSGGSIEQHIHIGKVDA
                     NNPSELDRMNRKFAKANKQAIRDLGGVPI"
     gene            76456..77160
                     /locus_tag="RD451_000489"
     CDS             76456..77160
                     /locus_tag="RD451_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDT7565781.1"
                     /translation="MNPDEPNFIWKNRNAVIDMNCIIEAELPDIMPNKRYETYTIQGR
                     SGELTETFDDYEPFDLEIEGITIPHSKLREVKRWLTGKSQLITHNDPDKYLEAICSMD
                     KEVPFENEWGFFYTFDVTFRCQPLKRKIGEAPKIFHSSVMDIFDHGDEIAHPYLEIES
                     NGGDITIAVGDKSLTILNTLAATIVVDTQLGKAIQEGLNLFTRGDWPVLQPEWNQVKI
                     SGKFKEVRFWNRSVYL"
     gene            77157..>78991
                     /locus_tag="RD451_000490"
     CDS             77157..>78991
                     /locus_tag="RD451_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDT7565782.1"
                     /translation="MTQEFIYAYKKMPDDLSVNGASLVDWEDLPEINRVLNGQYRFYG
                     NYSRSGQYRSYLKKGNFIKAKVPDGSWQYFEIYNVKKNLTSVSVTARHIGFMANKNFI
                     VKSFTDNGNGSQIMTNLKNSLAFDQKFNYLSNVGTTHQFTARQVAPVEAIIGSNNGNQ
                     NLTGVTSAELDMDNYDLKLVKQIGSDNGFRIDFGINLEAIEEEIDEESIVNSLYLVGG
                     VPDNDYDEDKEPIEYGYLEIDGVTNENRRIAKRENGDCKTVDELIKWGKTLFDNDRIH
                     EPKATHTVSMVALEHTLEYGDMYQELASLHFGDVAHVRAKELDIEIKERMVEYTYFPT
                     LGKYKDIVLGNDLSLYTSAVNTQAQELKKKIDNRTETLVQNVLNATAWITGNSGGHVV
                     FRPEKAPSEILIMDTPNVANAKRVWRWNLNGLGYSDNGVNGPFGIAITSKGEIVADFI
                     KVGTINAEVFETSFNAYGDVLKLVKGTLQIWNENKKIMELTKKGMEFWNRKESIGTIG
                     TTDSAGNPFPNAVTPTPLEENSLVIRTNGDGKYILISPTAEKGFVLLGNGKAYYFGDL
                     DIQGKLTVRGKEVIPGQNGGPSGGGETPGGYPDELKTDAEKRAWR"
BASE COUNT        26767 a        12989 c        16579 g        22656 t
ORIGIN      
        1 gaatcttatg attaaagagg ttgtgacaag acttttgtca cagccttttt tgtttataaa
       61 aataaaagtt gtagtggagg ctacgaagtt tactttgtct ttttacactt aatatttttt
      121 tgccaatttg gaatcaggat gttttgataa ctatcgtttt caattgatgg aagctatatt
      181 gtttgctatc agtgaaataa ttatatggta aacagtgttc tttttcttgt ttccattata
      241 aaaatcgtat cgggattttt cgttctttta aattgaacat ttctatctat ccgcgtgtta
      301 tcaacaaaac aaaatcaggt aaatagttga cgaaacagaa ataaatacat agtattatgt
      361 tttgaagcct aagtacaata gtctatagaa aaggagcgat accattggca aaacgcattg
      421 accgaattta tatgtatgtc aaagaaaaaa ccgctcattt aacaaaggca gaatatgatc
      481 aaggagtaac aacacaggaa attgctgaag tgttagggat tcagcgaaca aatagcagta
      541 aagatctgaa tcagctagtg cgcgaaggaa aactgataaa gacagacgga cgaccagtac
      601 gttacatata tcaaacactc gttacgcacg taaagccagt tacaaaacat gtagtcagtt
      661 acaaagaaac gccggtctct gaagaaaaaa atacactcca aatagatact aaggatatct
      721 ttgcaaaaat cattggagct aacggcagca tgaaaaattc agtggaacag gcaaaagctg
      781 cgattttgta tccgccaaga ggattaaatt gtttgattac aggacctacc ggatcaggaa
      841 agacttattt tgcacacgcg atgtatcatt ttgcaaaagc gcatcatgta atagatgagg
      901 aaacggaact gattgttttc aattgtgctg attatgccaa taaccctgag cttttgatga
      961 gtcatttatt tgggtacgca aaaggtgctt ttacaggcgc agatgaagaa aaaatgggga
     1021 ttatcgatca agcggatggc ggtatgctgt ttttggatga gattcaccgg ttgccgcctg
     1081 aaggtcaaga aatgatcttt tactttatgg atcatggaac ttacagtcgt cttggggaaa
     1141 caacgaaatc ccatgaagca aatgtacgga tcgtaggtgc gaccacagaa gacccaggtt
     1201 cttctctatt agaaactttt gttcggcgta tcccaatcaa tatcaaactt ccggcttttg
     1261 aaaaacgtcc tgcaaatgag aaagtcgatt tagtaaaaat catgattgcc cacgaagcaa
     1321 accgcacgca gcgaaagatt tctttgacag aagatgtagc aaaagcattg atcggcagtg
     1381 tgacctatgg aaatatagga caattgaagt caaatatcca gttagtatgt gcacgaggat
     1441 ttctaaatca tatgcaatca cccgaaatct cgatcacaat cgatgatttg acagaaggga
     1501 ttcgtagcgg attgattcaa ttagcaagca accgcagtgc aatggcagag ctttctaaaa
     1561 tattggagcc aaagataact gtagcaccaa atgatacgat catgaaaatc caatcggact
     1621 cctatgagtt accttataat ctatatgata tcatcggaga taaagcagct ttactgaagt
     1681 cggatggttt ggatcaagaa gcaatcaatc atttcatttc tacagatatc aacatccatc
     1741 tgaagtcttt ctataaagac catggttttt cttttaatgc agacagcaaa ttagcagaat
     1801 ttgtagatcc gaaaatcata gaagtgacca atcagattta tgtaatggtc aaaagatctt
     1861 taccatatga gtttcagcaa aactttattt atgctatgag cttgcatatc agttcttttt
     1921 tgaaaaaaat caacttagga gaagaacggc atacgaatga taacatccgt gagatggctt
     1981 ttgattttcc agatgaatat gctgttgcga aagaagtgcg tagttatatc gaaacgtatt
     2041 ttcaagtgga gattccagaa agtgaagact attacttgac cgttctactc gtctcgttac
     2101 gggcaaatca agcaagcggc agaatcggtg tagtcgttgc agctcacgga aacagcacag
     2161 caagcagtat ggtccaagtt gtccaacagt tgttagatgc agagaacgta cgagcagtag
     2221 acatgccttt ggatatggat ccgaaaacag cattggaccg aattgaacgc aatgtacaag
     2281 aagtagatga aggaagcggg gtcatactct tagtagatat ggggtccctt gcgtcgttta
     2341 attcgcaaat tcaaagagac actggaattc cagtacgtac tgttgatatg gtaacaactt
     2401 ctctagtttt ggaaactgta cgaaaggtct cagtattagg gacagatcta gatatgttgc
     2461 atgaatcatt gaaaaatttt cgaggttacg cagaaatatc ttctgtagaa tctgttcagg
     2521 aagcaaaacc tattcataag aaaaaagctg ttttggctat ctgcgcatct ggcgaaggta
     2581 cagcacaaag aatcaaagaa ttgatcgaac gagcggtaaa caagcgtcaa gaaacagaat
     2641 tagaagttct agctttgtcg attgtggaag tgaaagaaga actgccagtt atccaaaaag
     2701 aatatcagat catagctact actgggatta ctgatttgaa tatccaagcc ccatttattc
     2761 ctttagaacg ttttattgat caaaatatcg aagtcatttt ggatcagttg ctgatggaat
     2821 cagaattgga ggaaactgaa ttcatctccc tagatgaaga gtcagctaaa aatacgtgtg
     2881 ttgagtttat ctctgataac ttcatcttta ttaatggtag taagttaatc gatccaatgt
     2941 ggcaattttc tacacaaatc tctcagacga cgggaatcgg cgatgaagaa tatggattca
     3001 aaatcaacct agtgatgcac acagcaggaa tgatcgaacg tattattcgg aatgaaccat
     3061 tgactgtgga agaaaacgaa ttgacaaata caacgaatga tcctctttat agccaattgg
     3121 cagcctcagt tgttctgttg gaagatcaga taaaagtaaa agtgccgata gaagaaatgt
     3181 attatctgct acgtctagtc cataatcagt tagataaaaa agaatacact gtgccatgaa
     3241 tacacaaaaa cgatacactt ttatagtgta tcgtttttgt gtattggtta agaatccttt
     3301 aaattcaatt agtgtatcgt aaaaaagttg gcacgctttt tgcttatagt agtgtgtgct
     3361 aggaggtggt tgttcacaca gaaatgatag gggtttctgt gaagtagtga ggaagaagga
     3421 gttttgcaga tggatattcg attggcacgt atagatgatc gtttaatcca cgggcaagtc
     3481 gcaacagttt ggtcgaagca aacaggtgtt gaacgtatca ttgtgatcag cgatgtagtc
     3541 gctcaagata aattgagaaa gtttctacta aaagaagctg caccgccggg gatcacagca
     3601 aatgtaataa ccgtgcagaa aatgattcaa atctatcata gtggattatt atcacgagca
     3661 aaagtgatgc ttttattcac caatccccaa gatgttgaag cggttgtccg ctgcggtgta
     3721 cagttgaagt cgttgaatat cggcggtatg agttttactg aaggcaaatc aatgattacc
     3781 aattttgttt cagtaaatca acaagatatt gattcctttc gttacttgaa cagtcaagaa
     3841 gtggagttag agattcgaaa agtacctgct gacaggaaaa tccttttgat ggaactacta
     3901 gcgaaaatca aaaaggtgta gcaagaatgg ttgttggaaa aggtcaaata attctgttgt
     3961 aatggttagc aattattaat atttttgaat ttgttacaac aaaagtaaat aggaggtata
     4021 aatatggtag ggattatcct agcaagtcat ggacaatttg ctgaaggaat cttacaatcc
     4081 ggttcaatga tctttggcga acaagaaaac gtcaaagccg tgattttgaa accaagtgaa
     4141 ggtccagatg acttgagagc caaattggaa gaagcggttg cttcttttga taatcaagac
     4201 gaagtgttat tcttagttga tttatggggc ggaacaccgt tcaatcaatc aaacacatta
     4261 ttcgaagagc acaaagataa atgggcaatc gtcagcggtt tgaatttacc aatgttgatt
     4321 gaagcctacg catcacgctt ttcaatggaa tctgctcatg aaattgcagc acacatcatt
     4381 gaaacagcaa aagacggtgt aaaagtaaaa ccggaagaat tagaaccggc agaagcaccg
     4441 aaagcagcag ttgaagacgc acaacctaaa ggagcacttc cagaaggaac tgtggtcgga
     4501 gacggaaaaa tcaaatatgt attagcacgt gttgactcac gtctgttaca tggacaagtt
     4561 gcgacagctt ggacaaaagc agtgcaacca aaccgtatta tcgttgtttc agatgcagta
     4621 tcaaaggatg atctgcgtaa gagactaatc gaacaagctg ctcctccagg tgtaaaagca
     4681 aatgttattc ctattagcaa aatgatcgaa gtagcaaaag accctcgttt tggaaatacc
     4741 aaagcattgc ttttatttga aaatcctgaa gacgtattga cagctgttga aggtggcgta
     4801 gacatcaaag aattaaatgt tgggtcaatg gcgcattcgg tcggtaaagt cgttgtaagt
     4861 aaagtattgt ctatgggaca agaagacgtt gaagcgtttg agaagcttga acaaaaaggt
     4921 gtgaaattcg atgtacgtaa agtacctaat gattcacgcg ataacatgga tgatattttg
     4981 aaaaaagcaa aagctgaatt agcaaaagcg taataaataa tattaaaatt tataggaggc
     5041 ttatcatgtc tattatttca ataattttag tcgtattagt tgcctttcta gctggtatgg
     5101 aaggtattct tgatgaattt caatttcatc aaccactagt ggcatgtaca ttgatcggtt
     5161 tagttaccgg taacctcgaa gctggtatcg tacttggcgg tacgcttcag atgatcgctt
     5221 taggttgggc aaatatcggt gccgctgtag caccagatgc tgcattagca tcagtagcat
     5281 cagcaattat tttagtttta ggtggacaag gtgttaaagg tgttccttct gcgatcgcga
     5341 ttgccgttcc tttggctgtt gcagggttgt tcttaacaat gatcgtacgt acaatcgctg
     5401 ttccaatcgt tcatttgatg gatgcggctg ctgaagaagg aaacatccgt aaggttgaaa
     5461 tgtggcacat cattgctgta tgtttacaag gggttcgtat cgcggtccca gcagcagcgt
     5521 tgctatttat cccagcacaa actgtgcaat cattccttga atcaatgcca gcatggttaa
     5581 cagatggtat ggctatcggt gggggaatgg tcgtagctgt aggttacgct ttggtaatca
     5641 acatgatggc tacaaaagaa gtatggccat tcttcgttat tggtttcgtt gtagctgcaa
     5701 tttctcaatt aacattgatt gctctaggtg ctttaggtgt tgcattagct cttatttact
     5761 tgaacctttc taaaatgggt ggttcatcaa ataatggagg cggaagcaac tctggtgacc
     5821 ctttaggcga cattttgaat gactattaat cttgaaggag gaaaataaaa tggcagaaga
     5881 aaaaatcaaa ttatcaaaaa aagatcgttt agctgttgcg tggcgctcta ccttcattca
     5941 aggttcatgg aactacgaac gtatgcaaaa cggtggctgg gcattttcta tgattccagc
     6001 aatcaaaaaa ttatacaaaa caaaagaaga acgttctgca gcattaaaac gtcacttgga
     6061 attctttaat acacacccat acattgcttc tccaatttta ggggttacat tggctctgga
     6121 agaagaacgt gcgaatggcg cgcctgttga tgatgtagcg attcaagggg ttaaagtagg
     6181 tatgatgggt cctttagctg gtgttggtga cccagtgttc tggtttacag tacgtccaat
     6241 gctaggtgca ctaggtgctt cattagctat gggaggaaat atccttggac caatcatctt
     6301 cttcttaggt tggaacatta ttcgttgggc attcatgtgg tatacacaag aatttggcta
     6361 caaagctggt tctaaaatta ctgatgacct ttctggcgga ttgttacaag acgtaacaaa
     6421 aggtgcttca attttaggga tgttcgtatt agctgccctt gtagaaagat gggtatcaat
     6481 caaattctta ccagttgtat caactgtaaa attagataaa ggtgcttaca tcgaatggga
     6541 taaattgcct tcaggtggtg aaggaatcaa gagtgcattt gaacaagtta ataatggctt
     6601 agccctttct cctgaaaagg taacaacatt acaagacaac ttagaccaat tgattcctgg
     6661 tttagctgca ttaggattaa cattgttatg tatgtggttg cttaagaaaa aggtttctcc
     6721 aatcgttatc atccttggtt tattcgtagt cggtgttgtt ggacacgtca tcggactttt
     6781 ataatccata aaaatatagc tcgggcgttg tcccgagctt tttttatata gtatactgtt
     6841 cataaacaaa tatctggagg gagaaaatgg ttcaatcaat caatacaaaa gtagacttgg
     6901 taattgatgc tacttcgttt acgggtctga cagattacgg gcaaatcatg ataggtgata
     6961 atggttttga gttttaccat gcgcgagata gacgcaaata tatccaaatt ccatgggaag
     7021 aagtggatta tgtactagca tcagtcatgc taaagggaaa atggattcct cgatatgcca
     7081 ttcaaacgaa aaaaaatggt acatacacat tttcttccaa agaacctaaa aaagtgcttc
     7141 gtgcgatcag agaatatgta gatgaagata gaatggtaca atcattgagt ttctttgatg
     7201 tagtgaaacg tggtattcgt agtatgttta aacgcaagta aaaaataaag aaaacttcta
     7261 agaggaggtt ttctttattt ttttactttg cagaagaaaa tatgaaatag caaaaccaat
     7321 tatttgtccc ctttaaatcc catatgctaa aattgattag caaagaagga ggttatatta
     7381 tgagttggtt atggacattg attgttggag ccgtgatcgg agcaattgca ggtgcgatca
     7441 ccagtaaagg aaattcgatg ggctgtgtaa cgaatatcat tgctggacta gtcggttcaa
     7501 gtattggaca agcgattttc ggcgaatggg gaccaaaagc tgcaggtatg gcacttattc
     7561 catctatttt aggcgcagtg attttggtag cagttgtctc atttttcttt ggaaaacgat
     7621 cataagtttt tacaaaatag taaactaaaa ggagttgcag cgagactgtg actccttttt
     7681 ggctttattt atttaaaata aaaagaagtt ttccggaaat ttttatttaa ctgtcgtgta
     7741 cgaagaaaag tttgctataa tggaaaaaag cgtgcaaaga aagagggagt ttcattatga
     7801 tgctacgtgt agaaaaattg cgcaaaaaaa tgcaagaaga aaatttggat tcatttttgg
     7861 ttaccagtcc gtacaatctt cgttacttaa cgaactttac aggtacgaca ggattagctg
     7921 ttattacttt ggaaaaagca ttttttatta ctgattttcg ttataccgag caggcggcag
     7981 cgcaggctca agggtttgaa attattaaaa atgtcggacc tatttttgat gaggtagcaa
     8041 acttagtacg caaagaagaa ctgcactcat tagcttttga ggaaacaaca gtctcatttt
     8101 tagaatattc ggttttagaa gaaatcatcg atgcggaatt agtacctgtt tcacagatga
     8161 tcgaagaact cagagaagtg aaagatgaag aagaaatcgc tattatcgaa aaagcatgtc
     8221 atattgcgga tatggcatat gatcacatcc tgaaaatgat ccaaccgggc atgactgaga
     8281 ttgaagtcgc aaatcaacta gacttttata tgcgttctct tggcgcttca ggtgtttctt
     8341 ttgatacgat cgttgctagc ggattgcgtt cggctatgcc gcatggtgta gcaagcaaaa
     8401 aaatcatcga acaaggtgac ttgatcacat tggactttgg ttgctattac gaagggtacg
     8461 tttccgatat gacacgtaca ttcgctattg gtgatcctgg ggaaaaatta aaagaaattt
     8521 atcaaatagt cttagatgct caattagcag ttattgatgc tgcaaaacca ggaatgactg
     8581 gtgtccaatt agatgcagtt gctagagatt atatttcaaa acatggttac ggggaagcat
     8641 ttggacattc tacaggacat gggatcggtt tagagatcca cgaaggacca aacgtttctt
     8701 ctcgtgcaga aaagcaattt gtaccaggaa atgtgatcac tgatgaacca gggatctact
     8761 taccaggaat cggtggagta cgtattgagg atgacttgtt gatcacagaa gatggaaatc
     8821 gtgtgttgac tcgttcacca aaagaattga tcatcttata gtttcatcaa tagaagaagt
     8881 aagcgtaaaa atcagtgttc acagactttg ttatagaaaa tcactcgatt taatgataca
     8941 ctatagaaga acttttaagc tgtaagagat aataaagttg ggtgttttct ccaattcata
     9001 gcagtttgca gctgatcggc ggcagttttc ttaccacgtg atcactatgc cgcatcatag
     9061 agaattcgga tgtatctcgt gcttaggcaa agggaggaat aaataaatgg cagatgaaaa
     9121 aaatttgatt ttaaacgcaa accaagattt aggagagatc gtgatcgctc ctgaagtcat
     9181 cgaagtaatt atcgggattg cagcttctaa agtagaaggc gtatacggaa tgcgcggaac
     9241 ttttgccagc aatgtcactg aattattagg acgtgcagct cacggaaaag gtgtttactt
     9301 agcaaacgag gaagatggct tgaaagtaga tctttactgt tatctagaat atggtgtttc
     9361 agttcctaaa gtagcaatgg aaatgcagga acgggtcagc cagcaagtcc ttttcatgac
     9421 ggatatcgat ttatctgaag tcaatatcca tgtagtagct gttgttcctg aaaaattaga
     9481 acaaccaaca atcgaagaac tttttgaaga cgaagaggaa gagaatgaat aaagaattat
     9541 caagacacga gattcgggaa atggcattgc aggctttatt tccattagac ttcaatgcag
     9601 acctaacaaa agaagatgcg attttcaacg caatcgaatt agaccaccgc gacatgatca
     9661 acgaagatga atcagagttt gttcctgttt atcttgatac gctagttggc ggtgtctgtg
     9721 caaaaaaaga tgaattggat aaagtgattg aaaaacattt aaaaaacaat tggcacatca
     9781 atcggatctc aaaaatggat ttggtgatct tgcgtatcgc gatttttgaa atgacttatg
     9841 tgacagatgt accagcggct gttgctttaa atgaagcaat cgagttggca aaaacattta
     9901 gtgatgaccg ttcacgtaaa ttcgtcaacg gtgttttatc caatgtattg aaagaattag
     9961 aagctggggc gtaagtccta gcttttttct atgaatcatc ataaacctgt tataaatcgg
    10021 gaaaattcta tggtagaatg aaaacacaaa aaatatctgg gagtggttag atggcagaat
    10081 tgattaacgg aaaagaatta gctgaaaaaa tgcaggcaga gattgctgaa aaaatccaaa
    10141 aattgaaaga taatggtatc catcccggat tagtcgtttt attggtaggg gaaaatccag
    10201 ccagccaaat ctatgtaaga aataaagaac gtgtagcaaa agaaatcgga atccattcat
    10261 tggtagagcg ttatcctgag acgatttctg aagacgaact acttgcagaa attgaaaaat
    10321 acaatcaaga tcctagtttt catggtatat tggtccaatt accattgcca aagcatatag
    10381 atgaagaaaa gatcctgtta gctatccgcc ctgaaaaaga cgtagacggt tttcatccga
    10441 tgaatttagg cagactcctt gcgggtaaac cggacaagat tccttgtact ccatacggca
    10501 tcatgaaaat gtttgaagct tattctatcg atccggcggg taaacgagca gtagttatcg
    10561 gacgaagcaa tatcgtcggt aaaccgatgg ctcagctact cttgatggca gatgcaactg
    10621 ttactgttgc tcattctaaa accgaaaatc tggctgaact ggcacaagaa gcagatattt
    10681 tagtcgtagc aataggacgt ggacattttg tcacaaaaga attcgtaaaa ccaggtgctg
    10741 tagtgataga tgtagggatg aatcgtgatg ctaacggtaa gctgatcggt gatgtgaaat
    10801 ttgatgaagt ggagcctatt gcaggctgga tcactcctgt gccaaagggt gtagggccaa
    10861 tgactatcac gatgctgatg tatcaaaccg taaaatctgc cgaagctttt ggagcaggtg
    10921 aatagatggc acaagaatat ttaactgtca ctacattaac gaagtatttg aaaagaaaat
    10981 ttgatgccga tccttattta gaacgcgtat atttaacagg cgaaatatcg aatttccgtt
    11041 tacgtgccaa tgcccatcaa tatttcagct taaaagatga ccatgcaaaa atatctgcta
    11101 ttatgttcaa aggagcattc caaaaattac gattccagcc aaaagaagga atgaaagtcc
    11161 ttgtcgttgg gcgtatttca ttatatgaag cgggaggttc ttatcaaatc tatgtagagc
    11221 acatggagcc tgatggaata ggtgctttat atcaagaatt ggaagaacga aaagaaaagc
    11281 tgatgaagga aggccttttt caagggccta aaaaaatgct gccacgtttc ccaaagcgaa
    11341 tcgcggtcct taccagtcca agcggagcgg ttatccgcga tatcatcacg acggtgaaaa
    11401 gaagatatcc aattgtccaa ttggttttgt tcccaacagt tgtacaagga aaccaagcag
    11461 cggacaatgt tgtcaggaat atccagagag tagaagagat gggcaatttc gatacaatga
    11521 tcatcggtcg tgggggtggt tcgattgagg atttatggcc gtttaatgaa gagcgggttg
    11581 ctcgggcgat ttatcaagct aatacgccgg tgatttcatc tgtaggacat gaaacagata
    11641 ccacgatcgc tgatttagta gcagatgttc gggctgccac tccaacagca gctgcagaat
    11701 tagctgttcc tgttttgtca gaagagttga tgcgcattca agaacggcaa gctagattgc
    11761 agcaggcgtt tgtacgccag atccagcgca aacaagaacg gttcgagcgt gctcgacgtt
    11821 cctatgtatt tcggcagcct gaaagattgt atgaaggtca gaccatcaaa ttagaccagt
    11881 tgaaacagcg attatatcaa gctacacagc aaatttatca tgcgaaagaa aaacaaacga
    11941 tcgcattaag ccaccaattg gaacaagtgg ctccgcttta tcgagttaaa gcagctcgcc
    12001 aagaaactgc ttatctagaa aaacgcttag aagagaaaat ccaacaatat atgaaacaac
    12061 agcagcagcg ttttgctcaa gctgttcaat ctcttgattt gttgagtcca ttgaaaatca
    12121 tgggaagagg ctacagctat acgacgttaa atgatcaagt agtaaaaagt gtcaccgaga
    12181 ttcatcaagg ggatttgctg acgatccatt atcaagatgg aatcgttaaa ggacaagtac
    12241 aagagataga caaaggagaa taaaaatatg gaaaatccaa cttttgaaga gtcactgcaa
    12301 gaattagaaa aaattgtcat gcagttagaa caaggagacg ttccattaga atcagctcta
    12361 gattcgttta aacgaggaat ggaattaagc aaacattgcc aagatacatt agctaaagca
    12421 gaagagacct tgacgaaaat gatgacagaa tcaaatgaag aagttgattt tgacggaaac
    12481 gaggaaagct gagatgagat taactgactt ttcagctatt catctacctg ctgtagaaaa
    12541 agaaatcttg tcttttttag atgagcatac aacggataga ggactctatg atgcgatgag
    12601 ttattcagtg aaagcaggcg ggaaaagaat acgtccctta ttacttttaa cggccgttgc
    12661 ttcctttgat gagcctattg atgttcccgt ctatcaagta gcagctgctt tagaaatggt
    12721 gcatacgtat tccttgatcc acgatgattt gcctgcgatg gacaatgatg atcttcgtag
    12781 aggaaaacct accaatcata aagtattcgg cgaagcatta gctatattgg ccggagatgg
    12841 tttgcttaca ggagcattcc agctaatcag tatggcacac ttaggtaatt ctcctaagct
    12901 tctgctgctt cagcaattag ctgtttgtgc gggatcacaa ggtatggttg ctgggcaagc
    12961 tgcagatatc gagggcgaat cgaaaaagct ttctttagaa gaattagcat ttattcatga
    13021 aagaaagaca gggcatttga ttcgttatgc cttgctggct ggtggcatat tagcgaagca
    13081 acctgaagaa atcttattgc tacttcaacg attagccgaa catttaggtt tagcttttca
    13141 gataagagat gatctactcg atgtgattgg tacaacgaaa acattaggga aaacagctgg
    13201 taaagatgaa cgtatggaaa aaaatactta cccgcgttta ttaggcctag aaaagacacg
    13261 tgaggcgttg gagattgagc tgttatccgc caacaagatc atagacaaat tagaagagga
    13321 cgttttttct tttgatggcg ggctgatgcg ccagatgatc aagcaatttg atgtggagaa
    13381 atgagggaaa gaatggaaaa agaacgcgta gatgtattag cggtcaaaca aggattattt
    13441 gaaacaagag aacaagccaa acgttcagtg atggctggtt tgatttacaa cgaaaaaaac
    13501 gagcggtttg ataaaccggg agaaaaaatt ccagtgagta gtgaattaag agtcaaaggt
    13561 aaaaaacttc cttatgtttc tcgaggggga ttaaaattag aaaaagcact caaagcattt
    13621 gatctatctg ttgaaggaaa aacattgtta gatattggtg catccactgg cggatttact
    13681 gatgcagctt tgcaaaatgg cgcaaaaatg agttatgctt tagacgttgg ctacaatcag
    13741 ctagcttgga aaataagaca agatcctaga gtcgtcgtaa tggaaagagt gaattttcgt
    13801 tatgcaaaac ccgaagactt taccttagga attccagaag ttgctgttat cgatgtttct
    13861 tttatttcac taaaactgat gctgcctcca ttacatgcta ttttaaaaga agagggagaa
    13921 gtgattgctt taatcaaacc ccaattcgaa gcaggcagag aagctgtagg gaaaaacgga
    13981 attgttcgtg accctcagac ccatcaaaaa gttttagaag acattttgtc atttgcggca
    14041 caaggtggat atgatgtgct ggaattaagt tattctccga tcacgggggg agaaggaaat
    14101 atcgagttct tggctcactt gaggaaagta cccgaaagcg gaacaatcaa ttcagctatt
    14161 aatatggcag aagtggtttc aaatgcacac gaacagtttg accataaata aattgtaact
    14221 gtgaaaatca agtgagaagt atgcggattc ttctttatta taccaaggaa ataagctatc
    14281 attgattaag aagaatatgc taaggagcga agacgtaatg agaaaaaaag atcggcatcg
    14341 tttgattact cgattgttga gtgagcaaga tatccgaaag caggaagaat ttgttgaaat
    14401 cctgaaaagc aaaggaatat ctgttactca agctacgatt tccagagata taaaggaact
    14461 gaaactgatc aaggtaccgg cttcagatgg cggctaccgt tatagcatac cagctgaaac
    14521 aaacgaagat gtaaatacta aattggaaaa actattaaaa gacgctttcg tggcagttga
    14581 ccaaatggaa aaatttgtta ttttgaaaac attgccggga aatgcttcgg cagcagcaaa
    14641 tttgattgat aaacgttaca agaaagaatt attttcgatt atcaatgatg acgataatgt
    14701 tttgatgatt acacgaactg aagaccaggc agttttattg aagaaagact tcctgcatta
    14761 cctttaagtt gaggagcgaa tgtgatgcta caagaaatca gtattactaa ctttgcgatt
    14821 attccggaat tgcggctttc ttttcacgaa ggaatgaccg cgctgaccgg agagactggt
    14881 gcgggtaaat ccattattat cgatgcttta ggtctgttag caggaggaag aggttcaagc
    14941 gattatatac gtcaaggagc agaaaaatgt gtgcttgaag ggttgtttga actaccaaaa
    15001 caagaaggat tctctgaact gatggttgaa ttagggatcg aaacagatga ggacaatctg
    15061 attgttcgac gggatatgtc cttaactgga aaaaatgttt gtcgagtgaa tggtcatatt
    15121 atcacattag ctaatctgag aagaatcggc agttatttag tagatatcca aggacaaaac
    15181 gaacatcagg aactgctcca gcctgaatca catcttgctt tattggatcg ttttggagat
    15241 gtagctttcc aacagaagaa aaagagttat cagcaagaat atatctctta tcgtgagctg
    15301 gaaaaaaggg tacgaaaagt gcagcaaaat gaaaaatcct atgttcagag aatagatatg
    15361 ctccatttcc agcaagaaga aatagctgct gctgatttgc aagtcggaga agaagagaaa
    15421 ttaaaagaag aaagagaaaa acttagcaat tatcaaaaaa ttgctgatgg attagctgca
    15481 ggttacggag cactgacgaa taatgaacaa aacagtgtag atggtgttgg cttggccgtt
    15541 tcagaactgc aagggatcgc ccatctagat gtggagtatg aagcaattta tgaaaatatc
    15601 caaagtgctt actatttgct gcaagatgca atcggcgata tgagtcgtca gattgattta
    15661 ttggagttag atgagagtcg tttagaagaa gttacgcaac gtttagaatt aatccgacag
    15721 ttgaaacgta aatacggcga atccattgag tcaatattgg cttactatga cgaaatcacc
    15781 gaagagctag cttcttctga tttttcagaa ggtcaattgg acaaaatgaa agaggaacta
    15841 gagcaaaaag agcttctact tcagcaacaa gccgcagatc ttcatgaagc gcgtaaaaaa
    15901 atcgcaaaag aattggaaaa atccattctg catgaattga aaagtctgta tatggaaaac
    15961 actgagtttg aggtacgttt cttaaaagaa gaaaatagac aattgaatca tgatggattt
    16021 gaccaaatcg aattttacat tacgaccaat ccaggagagc cactgaagcc tttggtgaaa
    16081 gtcgcttctg gtggcgaact gtctcggatg ttgcttgctt tgaaaactat tttttcttct
    16141 gagcaaggtg tgacaagtat tatttttgat gaagtggata caggtgtgag cggaagagtt
    16201 gcacaggcca tcgcagataa aatttctcaa atatcgaaat actctcaagt tttgtgcatc
    16261 actcatctgc ctcaagttgc tgcagtcgcc gactatcaat attatattgt gaaagcagtg
    16321 attgatggac gtacgcaaac ttctgtttca gagttgaaaa caaaagaaag agaagaagaa
    16381 attgcacgta tgctggctgg aagtgagatt acaaaactca cactcgaaca tgcaaaagaa
    16441 ctattgaaac tcgcaaaaag gacctgagcc acctcgcagt ggttcaggtc cttttcagca
    16501 gctgatagct atattttatt tttacatgac actcattaca gcagtcaata caacagatcc
    16561 aatcgttaaa atcagcattg tccaaatgac aaattttgtt actttagcaa aagtacttgt
    16621 ttgttttttt tcacgcattg ttttcaacct cgtcattaat tagttgattc aagtgtacaa
    16681 tcttttttcc atttccacaa gagggctttt ttataaaaac ttcccttttt ttaaataata
    16741 ggtagttacg atacaaataa ataatgttaa tagaactagc catataaagg catcatccct
    16801 ttcagcaata ggtaacttaa tgttcattcc atagatactg ccgacgattg tcggtatagt
    16861 taaaataatc gttaaagaag ttaaaatttt cataatatta ttcagattat tcgatacgat
    16921 tgctgaaaaa gtctgattca tttgttctac tagttttaat tgaatgcgag aagtagtcat
    16981 tgcctgctct gtttccacca atacatcacg taaatgattt ttcaaagcat gattttcttg
    17041 gaaaagttta ttttgcgcta gttctttcaa tgcatctaaa ttagcagaag tcgcttctct
    17101 gaaataaacg aggctttttt ggatatccat gatttgataa agttgtttgt tttcagtgga
    17161 tacttgaagt ttggcttcca aagtatcgca ttgagattga agcgtagcta aataactgtt
    17221 gtaagagagt gtgacctgcc aaatgaattg aaagaagata ttgagattag gcgaaatatc
    17281 actttttgga aaggtctggc taaagacttt ctttaaaaac agtggttcat gattcgtaat
    17341 tgtgataagc ttctttttgg gcgtcaaaat aatagagagc gggtatgtat ccacttgaaa
    17401 ataaccgcta ggacttgttt tagcaaaagg atattgtaac aataataacg ctggctttgt
    17461 caactttgat tgattgaatt cttctgtacg ggaattttct gcatcgtcca atatggaagt
    17521 gatgtaatct gacggaattt caaattgatg tgtcagctga tgaatctctt cttgattagg
    17581 acgttctaca caataccaga tcgtttggtc agtttccttt ccggtattac gcagtttctc
    17641 attatctaat gtaaaatatt tgatcatgat tttcctcctg ttgcctgttt cttttattat
    17701 aacggatagg gaattggaat acatggaatg tgtttgtaag atatagaata taactgcata
    17761 aatttaaata aaatgaaaca gttgtgtaaa gtatatacag tatacttgaa gcaacgataa
    17821 aaaaggagtt tacgttcatg ggcacattca caccacttat cttgttttgg tatatttacc
    17881 cggtaatcgt tttgtttggt tgccaatttc ttgtaaaatt attttcgtta aatcgtcgtt
    17941 ttaaaataaa agcccctgat ttggcgattc cttttttgtg gggcggtatg catgcattgt
    18001 ctagaaatac agggacaatt tctatcttac cgtttttctt tatttctgtt ttgctaatgg
    18061 gaatttgtat tgctgttttc caagcatatt attatgaaga aattatttat ccgcgttatt
    18121 tcaagatgac ttggcgtttg gtttttctgt tgacaatcgt cttgtacgct gtcttgatca
    18181 ttgtgaacat actttcttac ctatgaaaaa aatagaaaag ctgtaaaaag tcttttaaaa
    18241 ggctttttgc agcttgattt ttaaaaaaat gtttatgaat aaaaaaagtt gttcccggat
    18301 ttcccagaaa aggtggtaga aagtggggga ttgtggtaga ctaattttag ttagtggagg
    18361 aatggggggc tttcaatgtt gatgggtgaa ttccaacata atattgatgc aaaaggacgt
    18421 ttaatcgtgc cctcaaaact tcgtgaagaa cttggcgaaa agtttgttct gacacgcgga
    18481 ttggatggct gtcttttcgg ctatccgatg agcgaatggg aaaatctgga agctaaactg
    18541 aacgaaatgc cgttggctaa aaaagacgca cgtacttttg tgcgattctt ctattcggct
    18601 gccactgaat gcgaacttga taaacaagga cgaatcaata tacccagcac gttaagaaat
    18661 tatgcagctt tgacaaaagg ttgcgtagtc atcggtgtat ctaaccgaat tgaaatttgg
    18721 gatgagacac gatggcaaga tttttctgca gcagcagaag agaactttga cgaaattgct
    18781 gaaagtatga ttgatttcgg actataagaa taggaagagg ctgactaatg actgaaacat
    18841 ttcaacacta tacagtcatg ttgaaagaaa cggtagatgg attgaacatc aaaccggatg
    18901 gcgtttatgt agactgtaca ctcggcggtg ccggacatag tgaatattta ttaagccaac
    18961 taagttctaa agggcatctg tatgcgtttg accaagatca aaaagcaatc gatcacgcca
    19021 agctgcgttt agcttcttat gtcgaacaag gtatggtcac atttatcaaa gcgaacttca
    19081 gagaattaga agaacgcttg agtgagcatg tagataaggt agacggcatt ttgtatgatc
    19141 taggggtttc ctctcctcag ctagatgaag cagaacgtgg atttagttat catcaagatg
    19201 caccgttgga tatgcgcatg gatcagtcag ctcctttatc cgcttatcac gtaattaatg
    19261 aatattccta ccatgaatta gtaaagattt tcttccgcta tggcgaggag aaattttcca
    19321 aacaaattgc tcgtgaaatc gaacgagtac gaaaaacaaa accaatccaa acaactggtg
    19381 agcttgtcga aatcattaaa caagtcatcc cagctcccgc aagaagaaaa ggcgggcatc
    19441 ctgcaaaaag aatttttcaa gctgtgcgga ttgcagtaaa tgacgaactc ggtgccgaag
    19501 aggcctcttt agaacaggca atccggttat tgaaagtcaa tggaagaatc agcgtaatca
    19561 cattccattc attggaagac agaattgtca aaagtatgtt taaagaatat agtacggtac
    19621 aagatctacc accgggactt cctgtcatac ctgacgaatt ccaaccagaa ctgaaagtca
    19681 ttactcgtaa accaatcctt ccttcagagg aagagctaac agaaaacaat cgatcacgca
    19741 gtgcaaagtt acgtattgca gaaaaaataa gaatgaaaga ggagtagaat gatggcagaa
    19801 ttaaagaaaa tgcaagatta cgaatatgat ttacctgaat tggtggatca gccggaacaa
    19861 caaatgcctg attcttcttc gaatcaagaa atcattcttc cacaatcacc ggcaaaacga
    19921 ttaaagcaga tttctgcttt ggaaaaaatt gctgtggcaa gcgtggcgat tgctattgtt
    19981 gctttatgtg ttttaacagt tatgctgcgc acaaatatca gcggagctga aaaagaaatc
    20041 acgtcaatac aaacagaaat caatgataaa aagcaagaaa aaacgagttt agaacaagaa
    20101 aaaaacgaac tttctcgtac tgaacggatt aaacaaatcg cagaagaaaa aggattgtct
    20161 attaatgacg acaatttaag gaaagtgaag taaatgagtc ttaaaaataa aattcggcgg
    20221 tttatggaaa agaaaaatct aaatccgatg aacaatcgca aaaaagtagg tatcatttta
    20281 tttgctacga gtattggatt gttcttttta tttgccgtcc gtttctcgta tatcgttatt
    20341 ggaggtcatg ttgctggtac ctcattagct gaaaaaacaa aacagttgta ccaaggaagt
    20401 gaagtagtaa aagcaaaaag aggaacgatt tatgatcgta acggtgtggc gctcgcagaa
    20461 gatgcctcct cttattcaat taaagcgata ctctcaaaaa catatacctc tggggataaa
    20521 aaactgtatg ttgaagaaaa gaattttgat aaaatagcag aaatcctgca taagaatctt
    20581 tctatagaca aaaaagatgc actgaatatt ttagaggacg gcgcaaaaaa agagctgtat
    20641 caagttgaat ttggtagcta tgggaaaaat atctcccaag aaaccaagca aaacatcgaa
    20701 gcggacatga aaaaagaagg tgtcgctggt ctttattttg tcgaccatca ggctcggatg
    20761 tatccaaatg gcgtcttttc ttctcatttt attggatacg cagttccaga caaagatgag
    20821 aatggcttag ttggtaaact aggtttggag tctgcttaca atgatatctt gagcggtaaa
    20881 gatggtaaga ttatttatca aaaagataat tttcaaaatc ctctgccagg tacagtggca
    20941 gaagaagaaa aagctgtcga cggacaagat atctacacga ctttagacag cagactacaa
    21001 agttatttag aaacactgat ggatcaagta aatgaagaat atcagccaga agaattgaca
    21061 gcagtcctga tgaaagcaaa aaccggagaa atcttggcaa tgggacaacg acctactttc
    21121 aatcctgaaa caatggaagg attgactgga aaagatgcta tctggcgtaa tttcttggta
    21181 caagatagtt atgaaccagg atcaaccatg aaagttttca ctactgcagc tgctatcgaa
    21241 gaaggagaat tcaacgagaa tgaaaccttc caatctggaa aaatccaagt agaagatgct
    21301 acgatcaatg accatgactt tggtgaaaaa ggtgtgctga ccatgcgtca agctctttca
    21361 tggtcaagta acgtcgggat ggtcatactg gaacagcgat taggcggacg atggtataac
    21421 tatttacaaa aactgggatt tggacaaagt actcattctg gattagatga tgaagtaaac
    21481 ggtgctttac ctacattaaa tattgtcgac cgagcaatga gtgcttatgg acaagcggta
    21541 ggtgtgacga atttccaaat gatgaaagct ttcacttcta ttgcgaataa cggtacaatg
    21601 attcaacctc gatatatcag caaagtggtg gatccccaaa ctggagaaga gcgaacaact
    21661 caaacagaag ttctagggca acctttttca aaagaaacaa cagaaaaagt ccgtgaatat
    21721 atgagagatg ttgtcgaaag cgaaaactac ggtagtgctt atggtgtata tagtgtacct
    21781 ggatacaatg tatcggcaaa aaacggaaca gcccaaatcg cttctgatac agggggatat
    21841 caaacaggag atacagccta cctgtattcg attgtggaga tggttccttc tgaagatcca
    21901 gactatgtct tgtatctaac aatgaaacac cctaagacat atgatcgaat ggcattggct
    21961 aaaatcgcaa atccattgat gaaacgggca atggatttta aagaaactga agaagattca
    22021 gatacagaaa caaaaacaga aaaagtatcc gtagccgatt atcgtaatct tgaagcggac
    22081 gttgcagcag ctgatgctca aaaaagtgga ctgcaacctg tagtgatcgg taatggtaaa
    22141 aaagtacaaa aacaatctac tgccaacggt gatcagttga tctctggaga aaaactgatc
    22201 ctatatactg gtggtgataa gctgatgcct gacgtaacag gatggtcaaa agcagatatc
    22261 atgaagctgg ggaaaatcct cggtattgaa gttagttttg atggagatgg ttattgtgtc
    22321 aaacaagaac ttgctccata tgaaaaaatc actgaagaca aacttagttt tactttagaa
    22381 gaataagaag agaaatagga gagaaaagag catggaatgg acacaagcat tgattcccat
    22441 tgtcagcagt tgtgcaatga caattgccgc aatgccgcta tttattggtt attttcaaat
    22501 gaaaaagcaa ggtcaggcga ttcgtgagga gggaccaaag tggcacaata gcaaagccgg
    22561 aactcctaca atgggcggct tagtgtttct gatcggctct attttgacag gaatttgggt
    22621 tggagcttgg caaaaacagc taactcctac tcttttcatc ttgctttttg tattagcgtt
    22681 atacggagta atcggctttc ttgatgattt tataaaaata ttcaagaaaa gaaacatggg
    22741 actgaactcg aagcagaaat tgattggaca gattctaggg ggaatcatct tttatcttgt
    22801 ttaccgttct gaaggttatc caggtgtatt gaatttcttc ggactagatc tacctttagg
    22861 aatcatttat ggtattttcg ctctcttctg gcttgttgga ttttcaaatg cagtaaatct
    22921 gacagatggc atcgatggat tagttgctgg cttaggaagt atctcttttg cagcttacgg
    22981 tctaattgct tggcatcagc atcagtatga tgtattaatc atttgcttaa gtgttttagg
    23041 aggtttactg ggtttcttcg tctacaacag aaaacctgcc aagattttta tgggagatgt
    23101 cggttcatta gcgttgggcg gacttttagc ggcaatttct ataatgctaa accaagaatg
    23161 gacattgctt ttgattggtt tgatctatgt tatggaaaca gcaagtgtga tgcttcaagt
    23221 tacttccttt aagcttacag gaaaacgaat ttttaaaatg tctccaattc atcatcactt
    23281 tgaaatgtgc ggatggtcgg agtggaagat tgatacagtt ttttggttga tcagcattgt
    23341 gacttcgttg atcacattat ggatcgtttg gtaggagatg acgggaaatg aaaaaaatat
    23401 caacatatga aaataagaaa gtgcttgtct taggactcgc aaaaagcgga gtaagtgcgg
    23461 ccaaattatt acatgaattg ggcgcacttg tcaccgttaa tgatggaaaa ccttttgacg
    23521 aaaatccgga agcacaagag ctgctttctt tagggataaa agtaataaca ggtagtcatc
    23581 caatcgaatt gttggatgaa gaattttcat tgatggtcaa aaatccaggg attccctaca
    23641 gtcatccttt agtagcaaaa gcccaagaaa tgggtattcc ggtaattacg gaagttgagc
    23701 tagcttacga agtagcggaa tgcccaatta ttgggattac aggaacgaac ggaaaaacaa
    23761 cgacaacaac gatgacagga ctactactga atgcaggagc agatcaagga attgcacgtt
    23821 tagcgggtaa tattgggtat ccagcaagtg gtgtagcgca agaagcaaaa tcagaagata
    23881 aaattgtgat ggaattgtct agcttccaac tcatgggaat cacagatttc cgccctcata
    23941 tagcggtgat taccaatatc tatgaagcac atattgatta tcatggtaca agaaaagaat
    24001 atgtcaaagc taaatggaac cttcaaaaaa acatgacaga aaaagattat ctgatcctta
    24061 actggaatca gtcagaacta caagaattag cgcaaagaac aaaagcacgc gtactgcctt
    24121 tctcgacaaa agaagtgttg gaagacggtg tgtatgctga cgattactca atatactata
    24181 aaaaagaaaa aataatggaa atatctgaac ttggcgtacc aggtaagcat aatgtagaaa
    24241 atgcactagc tgctatttct gtagcaaaat tgtatggtat atcaaatgaa gctatacgag
    24301 aaacgttgca ttttttccat ggcgtaccac atcgtacgca atatgtagga gaaatccaag
    24361 gcagaaaatt ttataatgat tcaaaagcaa ccaatatttt agcgactaaa atggctctaa
    24421 gtggatttga aacgtctaag gtcgtgttat tggctggcgg attagacaga ggaaatacat
    24481 ttgatgaatt aattccttca ttaaaaggaa tcaaagcaat ggtcgtattt ggccaaacaa
    24541 aagaaaagtt gatggatgct ggaaaaaaag caggcatcga gacaatagta acagccgatt
    24601 ctgtagaaca agcagttcct ttagcattag aaaacagtac agatggtgat gtagttttat
    24661 tatcaccagc gaatgccagc tgggatcaat acccaaattt tgaaactaga ggaaacagat
    24721 tcatggaagc tgtgaaccga ttaaaataga aaaagtagaa gcgagcgata aaaaatgaaa
    24781 attttggtta caggcggagg aacaggggga catatttatc cagctcttgc ctttgtcaat
    24841 tatgtaaaga ctcaagaacc gaatgctgaa ttcatgtatg tgggagcaaa acgaggtcta
    24901 gaaaacaaaa tcgtccctga tacaggaatg cctttccata ccttggagat tcaaggattt
    24961 aaacgaaaaa tttccatgca taacatcaag acggtccgat tgtttcttaa gagtatccgt
    25021 caagcaaaaa aaatcctcag tgattttcaa ccagatatcg ttatcggtac tggaggatat
    25081 gtttccggag cggtagtgta cgctgcagcc aaaatgggta ttccaacagt tatccatgaa
    25141 caaaacagtg taccaggtgt taccaataaa tttttaagcc gatatgtgga tcggatcgct
    25201 ctttcattta aagatgcggc ttcctttttt cctgaaaaca aagcagttct tgtaggtaat
    25261 cctcgagcac aagaagtagc agatactaaa aaatcagata ttttgaaaac atttgatttg
    25321 gatccagaaa agaaaacagt cttgattttt ggcggtagtc aaggagcact taaaatcaat
    25381 caagcagtat cagttttttt aagtgaatat attccttctt cttaccaagt tttgtatgct
    25441 tcaggagata gatattatga agagatccta aataaaataa atcctgaaat acaaaatatt
    25501 agtgtccagc cttatatcaa aaatatggca gaggtcatgg cttccagtga tctgctggtg
    25561 gggcgtgctg gtgcaacttc gatcgcagaa ttcacagctc tggggttacc ggcagtgttg
    25621 gttcccagcc catatgttac gaatgatcat cagactaaaa atgcaatgag tcttgttcac
    25681 gcaggagcag caaaaatgat tgcagataat gaactaacag gtgaatcact aagtcagaca
    25741 gtcaacgaaa tcatgggtga tgaagaattg caaaagcaaa tgtgccgagc ttctaaagaa
    25801 caaggaatcc ctgatgcttc aaaacgtctt tatgacttag taaaacaaat aatcaaaaaa
    25861 taaaggcggt ggtcttagtg agtaagaaaa aagaaccaaa aaaattgtct catccgtctt
    25921 ctgatgaaaa caatttgact ccttggcaaa aggctaaccg aaaatatctg gcagaacaag
    25981 agatgaaaaa ccaagagcca aaaaaagaag acataacatt agatacaccc ctttcagatt
    26041 ctgaagaaga aaaaacggtt caagaggaac agcaagaaga aagccagtcc gagaaaaaaa
    26101 tcgaattttt tgaagagatc aagcaaaaga aaaacggtgg accatataac ggttcttttt
    26161 tgaaccggct gcccaattta aaaagtcaac ggcacaaagt actatttcgt cggttagctt
    26221 tgatcatcac tgtattgggt ataccgctga tttttttgat ctattatgtt tctccttata
    26281 gcaaattaca agcagttgca gtatcaggca ataagacagt caacagccaa gaaatcatct
    26341 ctgatacaaa attgtcatta ggagaaaatg tttggggaca gtattttcat cgatctactt
    26401 atatcgatcg ccttaaaaaa gcacagccaa gaatcgaaac agcaaatata catttcaaag
    26461 ggatgaatga attcgatttg gatgtaacag aatataaaga gattgctttg atcgcaaaaa
    26521 acaatcaata ctacccagtg attgaaaatg gaacagtatt agatgaaaaa gtagcaaatc
    26581 ctacaaaaaa tctccctatc ttggaagagt tcaaagactc tgcaaaaatc aaagaattaa
    26641 caaagcaata caatcagtta tcatcagaat tacaaaaagc aatttctgaa atcaagtaca
    26701 cgccaagagc aagcaataaa aatctgatcc aattgaatat gaatgacggc aatcaagtta
    26761 ttgtaaatat caataatctt gcgaaccaaa tgaaatatta ttcgcaagta gccaaagata
    26821 tggatgaaaa aggtgtgatc gacatggaag ttggtatctt ctcgcatcct tacggtagca
    26881 ctcaagaaac ggaagaatcg ggccaatcgg aagaaacaac tgaaagtgaa gaaaatgcgg
    26941 atcaaacaaa cgaatcaagt gaagaggcag aaacgcaaaa agcacaaaca cctggatcgt
    27001 ctagcacaaa cggatcatct gattcaaatg attcaagtga aacaagtcaa atagaagata
    27061 atccaagtac aactccgtca agtttaaatg aaaattgata aaacaacttt aaaaagtaag
    27121 aatgtacttt ctaaaaacca gtaatttatg gtagaattgg aagcagtgaa tatatctatt
    27181 aataagtata ttttaaaacg gacgctagtt gttcgcttgt atatggaata gtaagtagga
    27241 gggaatccca ttcatggcaa aaacaggaat gtatgtaggc cttgatattg gaacgacatc
    27301 tgttaaagtt gtcgtggctg aatatatcga cagccaaatg aatattattg gagtaggaaa
    27361 cgcaaaatca gaagggatta accgaggcat tatcgttgat atcgataaaa cggtccaagc
    27421 gatacaacga gcagtacgac aagcagaaga aaaagcaggt atccagatca aaggcgtaag
    27481 tgtcggtttg ccagcaaaca tgcttgaagt agaaaattgc cagggaatga ttgcagttaa
    27541 cggagattca aaggaaatca ccgatgaaga tgtcagaaat gtggcttcag ctgcccttgt
    27601 tcgttcaata cctcctgaac gtcaaatcgt gtcaatattg ccacaagatt ttactgtcga
    27661 tgggttcgag ggaatcaaag atcctcgtgg aatgatcggc gtaagattag aaatgtacgg
    27721 tctgttgttt acaggaccta aaacgatcat ccataacata cgtaaatgcg tggaaaatgc
    27781 cggattaatc gtcaacgaaa tggtgattac tcctttagcg ctgactgaat caattctttc
    27841 tgacggagaa aaagattttg gtacgatcgt cattgatatg ggtggcggcc aaacaacaac
    27901 ggctgttatg catgataagc aattgaagtt taccaatctt gaccaagaag gtggcgaatt
    27961 tgtcactaaa gatatctcta ttgtattaaa tacgtcattt aacaatgcag aagcgttgaa
    28021 aataaactac ggggatgcat acccagaacg gacatcacca gatgaagaat ttccagtaga
    28081 tgtgattggt cagtcagaac cagtgaaagt cgatgaacgc tacttgtcag aaattatttc
    28141 agctcgaatg gaacagattt tcaacaaagc aaaagatgca ttggaccaaa tcgaagcatt
    28201 agagttgcca ggtggcgtcg tattgacagg cggagctgct agtcttcctg gtgttgtgga
    28261 cttggcacaa gaaatcttcg gcgtaaatgt aaaattgtat gttccaaatc acatggggct
    28321 gagaaacccg gtatttacaa atgtaataag tatcgtggat tattcagcaa acttgagtga
    28381 agtgtatcaa ttggcaaaaa ttgctgttac gggtgaaacc tcagcagctc gtcaaatggt
    28441 agttgaacaa gaaacaacaa acacatatga gagctatgaa gcacctgaag aaacaatcta
    28501 cgatgagccg gaaccaaaag agtccggaga aaatgtaaaa aataaaatca agggtttctt
    28561 tacaaatatt tttgattaat tcatcctggg aggaataaga tatggaattc tcaattgata
    28621 ataatatcaa tgacggcgca gtaatcaaag tcatcggagt cggtggtggc ggtggaaatg
    28681 ctgtaaaccg aatgattgaa gaaaacgtta aaggtgttga attcattaca gccaacacag
    28741 acgtgcaagc attaaaaaat tcaaaagctg aaacagttat ccaattaggc cccaaatata
    28801 ctcgtggttt aggtgctggt tctcagccag aagttggaca aaaagcggca gaagaaagtg
    28861 aacaatcctt acgcgaagct ttagacggtg cagatatgat tttcatcact gcaggaatgg
    28921 gtggaggaac cggtacaggt gctgcaccaa tcgttgcagg tatcgcgaaa gaattgggcg
    28981 cattgactgt tggtgtcgtg acacgtccat tcacttttga aggaccgaaa cgtggccgtt
    29041 ttgctgcaga aggtatcgct cgtttgaaag aaaatgtgga tacattatta attatctcaa
    29101 ataaccgttt attagaagtt gtagataaaa agacaccgat gcttgaagct ttccgtgaag
    29161 cagataatgt tttacgacaa ggtgtacaag gtatctctga tttgatcaca gcgccaggtt
    29221 acgttaacct tgactttgct gacgtgaaaa cagtgatgga aaaccaaggt acagcattga
    29281 tggggatcgg tgtggctagt ggagaagatc gcgtagtaga agcaacgaaa aaagcaatct
    29341 cctctccatt gcttgaaaca tctattgatg gagctgaaca agtacttctt aacatcacag
    29401 gcggtttgga tatgacattg ttcgaagcac aagatgcttc agatatcgta gcaaatgcag
    29461 caactggcga tgtaaatatc attctaggta catctatcaa tgaagaaatg ggcgatgaaa
    29521 tccgtgtgac ggtcatcgca acaggtatcg atgaatcaaa aaaggaacgc aagtctagcc
    29581 gaccagctag acaagcacaa atgcaatcac ctgctcaaaa gactgtatta gatatggatc
    29641 aagctaaacc aacttcttca gaagaagaaa acagttttgg cgattgggat atcagacgtg
    29701 aacaaaatgt tcgtcctaga gttgatgatt ccaattttga caatatcgaa aaaaaagaat
    29761 ttgatacatt caaccgcgaa gaaacaaaat ctcatggcga tgatgaatta aatacgccac
    29821 cgtttttccg tcgtaaaaaa taaaggagag gaagagcaca tgattgctga caacttgcag
    29881 aaaatcaagc aagaaattca ggattcgtgt gctcttgttc atcgtgatcc gaaagaagtt
    29941 acattagtag ctgtaacaaa atctgttgaa tccgctcaag ctgaagaatt ggttagagct
    30001 ggcgttatga attgtgcaga aaaccgagta gataaattat tagaaaagaa acaagattta
    30061 tttgattttc ctgaaataaa gtggcattta attggtaatt tacagcgcag aaaggtaaaa
    30121 ttgattgtaa atgaaattga ttactttcat gcgttggaca gtttaagatt agcagaagaa
    30181 atccagaagc ggttagagaa agaattatcc tgttttattg aagtaaatgt ttctggtgag
    30241 gaatcaaaac atggaatttc accagatgag cttttaccgt ttgtggaatc tttagctgcc
    30301 tgcacaaaaa tcaaggttgt tgggttgatg actatggcgc ctaaagaagc ttctgatgag
    30361 caaatccata aagtgtttgg tacgctgaaa gaattgcgtg atcttgttca agcaaaaggt
    30421 tatgcccatg caccatgtag tgaattaagt atggggatga gtcaagactt tcaaattgcg
    30481 attgaagaag gtgcaacatt tatccgtgta ggaacagcgc tattcaaaga cgaataaagg
    30541 aggaacaaaa atgccgcttt taaacagagg agcaattgct aattttttcg gattagctga
    30601 tgaggaagag tacgaatacc aagattatcc tgaaacaaca aaaaaggctg tacagccaac
    30661 taaaaaaaat acaacacaga atcaatcaac tcattctgta tctgctgcga atactcatga
    30721 aaaacaaaaa acggcgactt cacgtcctgt aacgcatgaa agtattcagc cggctgaaaa
    30781 gaaaaaagta attgaactac atcaatcacc tacaaaaact gtagcgaaag aaagaacagc
    30841 ttcaagaacc tctacacaac ctaaagcaaa tcttgctgga aaaatcactg taatggaacc
    30901 aagagcttat tctgaagcta tggcgattgc taaacgaatc attgctggag aagcaacctt
    30961 agtgaatttt catttagtag aagaaaaaca agcgagaaga atcgttgatt ttctaacagg
    31021 aacagtttat gcactagatg gagatatcaa acgtgttgga gatgagattt ttctttgtac
    31081 accgactggg atggagattg acagttcaac cgctcaatct tttgcagatg cgaatttgtt
    31141 tgatctgtaa gaggaggaac tacgatttat actattgcac tattacttca tttacttcaa
    31201 cgggcagcct atttctatag cattatcttg atggtatatg cattgctctc ttggtttcca
    31261 ggcgggtatc aatcagggct aggacgatta ttagctaaga tctgcgaacc gtatatcagt
    31321 ttgttcgatc gtctgccttt gaggattgga cccttggatt tcacaatttt aggggcaatc
    31381 ctgatcttga acttagccgt acaaggttta gcacagatcg ttatatggat aactgtccat
    31441 ttagtttatt gattgaagca acaaaatctt tattctcaga atagatagga ggggaaaatt
    31501 ttggatgcaa atgtatacca gcactttcgg gcagatgaac gtacatttat cgattcggta
    31561 ggcgattgga ttgaacaggt tcaaggacaa tatgcaccct atctgaccga atttcttgac
    31621 ccaagacaat cctatatttt agaaacactg attcgacaaa gcagtgattt gcgtttcatg
    31681 ttttatggcg gatatgaaca ggcagaaaga aaaagatgtt tgattttccc cgattattac
    31741 gaacctgtag aggaagattt tgaaacagca ttgtatgaaa tccattatcc tagcaaattt
    31801 gccagcctaa gtcatgggaa aatccttgga actttagtgg gaacggggat caaacgctct
    31861 tactttggcg atatcatctc ggacggtgat cgctggcaag tatttattgc aaatgaggtg
    31921 gatcattttg ttgctgcaca agtaacaaag attggaaagg ttgctgtacg cttggaacca
    31981 atcaaataca cagaaatgat tatgccgaaa gatagctgga cacaagaaag aggaacagtt
    32041 agttccatgc gactagacag tgtgatctct gagatttata atatttccag acagcggtcc
    32101 aagcagctga tcgaagctgg taaagtaaaa gtgaactgga cagaaaatac aagacctgat
    32161 tttgtacttg aactattaga tattatttca gtcagaggtt atggcagagt ccagatccaa
    32221 gaacttgagg ggaagacgaa aaaagaaaag tacagggtac tgttcggtgt attacgtaaa
    32281 taaaataaaa aggtggttta ctcatggctt taactccatt agatatccaa aataagacat
    32341 tcccgacaaa aatgcgggga tataatcaag acgaagtaga tgatttctta gatttagttg
    32401 ttcgtgacta tgaggaattg actcaaagaa atcgagaatt agaaaaagca gtcaaacatt
    32461 ctgaagaaaa acttgagtac ttcaatgaat taaaagatgc tttgaaccaa tcaatcatcg
    32521 tagctcaaga tacggctgat aaagtaaaaa caagtgcaag caaggaatcc gaagtgatcg
    32581 ttacttctgc acaaaacaaa gcagatgagt tagttgcgaa cgctgaaaaa cgtgcacatc
    32641 aattaacaac tgatgcagaa gaaaaagcaa gaaaaatctt gacagatgca acagaaaaag
    32701 caagacagct tgcgacagaa actgaagatc ttaagaaaaa aacacgagta ttccatcaac
    32761 gtatcagctt gatgcttgag tctcaattag aacaagtgaa aagtccggaa tgggatgaaa
    32821 ttttacaacc attctccagc tacgtgactg acagccatga agtgatcaaa gaagttttag
    32881 caaaacagct tgacaatgaa aatgatactg atgtaaactc agacacagga gtcatagaag
    32941 cacctatgac ggcatttgat acacaggcta ttgatatctc gatcgtgcct ggtgaaaatg
    33001 aaaacgagta gaacagaaaa gcactttgtt attcttaaag cgagccgatg agagtggaag
    33061 ttcggtaaga cactgcatgg tgaaagatcc tctacttgag acctgctttt ccgaaattag
    33121 agtaagaagc agcggctgac ctcgttattg gtcacagaga gtttgcacta gatagatgca
    33181 actaaatttg ggtggtacca cggcatgttc gtcccttgcg gctgaacatg cttttttgtg
    33241 tccggaaaac aaataaagga gtgtatggtt gaatgaaaat gaaagaaacc ttgcaattag
    33301 gaaaaacaaa attccctatg cgtggtaatt tgccaaaccg agaaggcgag tggcaaaaag
    33361 aatgggaaga aaatcgaatc taccaaaaaa gacaagagtt gaacgaagga aaacctagct
    33421 ttgttcttca tgatggacct ccatatgcca atggtaatat ccatttagga cattcattga
    33481 ataaaatcag taaagacatt atcattcgtt caaaatcaat gtctggctat cgtgcaccat
    33541 atgttccagg atgggataca catggattgc cgattgaaca agtattggct aataaaggcg
    33601 tgaaacgtaa agaaatgtcc atggcagaat acttggaaaa atgtcgtgaa tatgcacttt
    33661 cccaagtaga taagcaacga gcagatttca aacgcctagg agttgcagga gattgggaac
    33721 atccttatgt tacattagat ccttcttatg aagctgcaca agtacgcgta tttggtaaaa
    33781 tggctgaaaa aggctatatt tacaaaggat tgaaaccaat ttactggtct ccgtcaagtg
    33841 agtcttcttt agcggaagct gaaattgaat ataaagatgt aaaatctcca tctatttttg
    33901 tagctttcaa tgtcaaagac ggcaaagata ttcttgatga agatacagct tttgtcattt
    33961 ggacgacaac accatggaca ttgccagcaa accaaggtat tgctgtaaat ccaaaattta
    34021 cgtatgtatt ggtggaagcc gatggccgta agtttgtcgt agcgaaagat ttgctagaaa
    34081 cagtccaatc agaaatcggt tgggaaaatg taacagttct aaaagaattt gctggacaag
    34141 aaatggaata tatgactgca agtcatccat tctatgaacg tgaatcactt gtgattttag
    34201 gcgatcatgt tactttagac gctggtactg gattagtcca tactgctcca ggacatgggg
    34261 aagatgacta tatcgctggt agcaaatata aactatctgt agtgtcacct gtagactcaa
    34321 aaggattgtt tacagaagaa gcacctggat ttgaaggtat cttttatgac aaagcaaatc
    34381 ctatgatcac tgatctatta aaagaaaaag gagctttgct gaagctagat ttctttactc
    34441 atagttatcc tcacgattgg cggacgaaaa agcctgtgat ctatcgggca actccacaat
    34501 ggtttgcatc tatcgataaa ttccgtcaga atattttgga tgaagtagaa aaagtagagt
    34561 gggttatccc atggggtaaa acacgtttgt ataatatgat ccgtgaccgc ggcgattggg
    34621 taatttcccg tcagcgtgca tggggagtac cacttccgat tttctatgct gaaaatggag
    34681 aagcaatcat cacaccagaa acaatcgaac atgtggcaaa attatttgct gaacatggat
    34741 caattatctg gtttgaaaaa gaagcgaaag aacttcttcc tgaaggattt acccacccag
    34801 gttctcctaa tggcgaattt acaaaagaaa aagatatcat ggatgtctgg tttgattctg
    34861 gttcttctca tgaagctgtt ttacgtcagc gaccagaatt atcattccca gcagatatgt
    34921 atttagaagg atcagaccaa tatcgtggct ggttcaactc aagtatcacg actagtgtgg
    34981 ctatcaatgg tgtagcacca tacaaatcag ttatttctca aggatttgct ttagatggtg
    35041 aaggccgtaa gatgagtaaa tctttaggaa acatcattgc accagaaaaa gtgatcaaac
    35101 aatttggtgc agatatcctt cgcttatggg tatctagtgt agattatgaa gcagatgttc
    35161 gtgtttctat ggatatctta agtcaagtgg cagaagtata tcgtaaaatc agaaatacga
    35221 tgcgtttctt attagcgaat acagaagatt tcgatcctaa aaaagatact gtttcgtaca
    35281 atgatttacg ttctgtagac aaatatatga ccgttcgatt gaaccaagta atcaaagaaa
    35341 tccgagaaga agggtacgac aaatataact tcatgcatat ttaccgtaca gttatgaact
    35401 tcttgacggt tgatctatcg tcattctacc tggattttgc taaagatgta gtttatattg
    35461 aagcagaaga tgattatcaa cgtcgttgca tgcaaactgt tttctatcaa acagctgtag
    35521 ctttgacaaa attattgact cctatcattc cgcatacagc agaagaaatc tggtcattcc
    35581 tgaaagaaga agaggagtac gttcagttaa gcgagtttcc tggttatgaa gagtttgcaa
    35641 accaagaaga attgatggat acctggactg ctttcatgga cttccgtgat aatgtcttaa
    35701 aagcattgga agaagcaaga aacagcaaat tgattggtaa atctttggaa gcaaaactaa
    35761 ctgtttatcc aaaacaacaa gttcgtgaaa tgttaaaagc tttggatgca gatattgcac
    35821 aattattgat cgtttcacca gactactttg aagttatggc agcagatgaa caagtgccag
    35881 ataacgctat ggtatttgat gatgttgcta ttacagtgga aaaagcagac ggggaaactt
    35941 gcgatcgctg tcgccaagtt cgtaaagatg taggagtaga tgaaaaactt cctcatctat
    36001 gcggtcgttg tgcaaaaatc gttgaagact tctatcctga agctgtagct gaaggattcg
    36061 aagaaaagta aaagggaaaa gggggtgtga catgttcttt gtcacacccc cttttgttat
    36121 caatcgttta attttccacg ttcacgatac cagttatctg gttgccagat ccattcgaat
    36181 ccgtcttttt caagtagttc gaaagctgct ttaggtccca ttgatccagc tttgtagttg
    36241 ggaaaatccg gttgtgtttg gtcccaagct tttcgaatga catccacgat atgccaagat
    36301 tgagcgactt cttcccaatg agagaagttc gttccatcac cattcaacgc atctaatagt
    36361 aatttttcgt aagcttctgg gctattttca accatttctg cactatttct aaattccaat
    36421 ttgattggtt ccgtttcaaa tccttgccct acttctttcc cattcaagga taaagaaaat
    36481 ccttcagttg gctgaatata gatcgttaga acattaggtg gaagtgtcgt atcgtcacat
    36541 ggttcatcga cagatgtttt gaatacatta acaggaactt gtttgaatac gatgttgatc
    36601 cgagtccctt tttcagtcaa acgtttgcct gtacgtacat agaaaggaac acctgaccaa
    36661 cggaagttat cgatagtgaa tttgcctgcg acgaatgttt cagtctctga ttgagcatcc
    36721 actttgtctt cttcgcgata gcccttgaat tgtacaccat ccaattcacc ttgagcatat
    36781 tgcccgcgaa cgaagttttc taacacttct tcttcgttat aaatgcggat agctttcaat
    36841 gctttgatct tttctgtacg gatttctttt tcggaaaatg ctactggcgg ttccattgca
    36901 agtaatgcta caacctgtaa aatatgattt tgcaccatgt ctttaagtgc gccactatga
    36961 tcgtagtagc ccccgcgatc ttctacaccg aggttttcgc caaaagtaat ttggatattg
    37021 tcgatatagc gattgttcca ttgagcctca aaaatattat tggcaaaacg gatagctgag
    37081 atgttttgga tcatttcttt tcctaaataa tgatcaatcc tgaaaatatc ttgttctggg
    37141 aatacttctc tgatttgctg gttcaattca aaagcagact ggtaatcaga accgaacggt
    37201 ttttctatga tcaaacgatt gaagccattt tttgtcataa tattttgtga tttcaaatga
    37261 gaaacgatcg ttccaaaaaa ttgaggtgcc atagccaaat aatagacacg gttaccgttt
    37321 aattgatagt gtccatctaa tcggtcagac aattctttta atgtctgata atgcgttgaa
    37381 tcatttacat catgggattg atagtaaaaa tggcttgcaa aggtagttgc ttcttcatct
    37441 gaaggattca atgcacggat tgtttctttg acaacttcac ggtagtgctc atcgctccag
    37501 ggacggcgag cggttccgat tacagcaaaa tgctcgccta aatttccttt tctgtaaagg
    37561 cggaacaaag acgggtacaa tttacgctgg gctaggtcac ctgtaccgcc gaatatcgta
    37621 aacaatacat ttttttcatt agacatgtgg atacactcct ttatatttta tcgacaaaaa
    37681 tcgtgctggc cgccttaaag ctgacgggga ttttctttct atcattttgg atagtgatcg
    37741 gtccttcata agctgcgatg tcaacgatct catattcttc gttgatattc aggtcaatag
    37801 tgactaagta atccaacaat tctttttcat caagcactcg tgcgatacgc acttttgtac
    37861 cgacaggata ggactccaat gtttgtcggc gttcttcatg gacaacttcc tcttttttag
    37921 gaatcgatcc tccatgagga caatgttcag gatgattcaa atagttttct aaatgatctg
    37981 caagatgttc cgaagtcaca tgttccaata cttcagcatc atcatggact tcattccagc
    38041 tatagtctaa atgttcaact aaaaaaactt cccataagcg atgtttgcga atcagactgc
    38101 tagctttttg cagtccgctt gcagtcaatt gtacaccttg ataaggggaa tgttctacaa
    38161 gctcttcttt cacaagttta gaaatcattt cactgacaga tgcagctgag acatctagac
    38221 tagatacgat ttgtttattg ttgactttcg ttgtatctcc acctagttct aaaatgattt
    38281 tcaaataatc ttctcgattt ggtgtcatat tcgatcatcc tttcatggta aaaaaccatc
    38341 attagtaagt gtaacaaaaa aaacgttaat tgactatttt tctaaataaa aaacaaagga
    38401 tttttagacg tttttacaac aaaaaacgaa agatgataga gaagactcat tctttcgttt
    38461 ataaaggata tatatataca ttgggaggga tctatttttc agataacaac ttatatgaag
    38521 tgtctgcaga ttcgtcataa agagtttgtt cgggataaga aaagataaga taaaaaccat
    38581 actgatcacg tacgactaaa cgatattcat ctatttctac cacagatgtg ccaagagact
    38641 gaccgttgat caaaaacgtg taatcagatg taatctgtaa ttgttgtttt tgctggctat
    38701 cactaaagaa ccatgtacct tgatactttg agagtccttc tgacttttcc gcttgttttt
    38761 tctttttcaa gtaaataaaa cttgagagaa cggtaatgag tgaaccaaga aaatagatca
    38821 ttttttttat caccaaatca ctcctttatg agaaaataat cgcatagaca tattctttct
    38881 tctttatttc attgtaccga ataaaagcta aaatttctct aagactttcg actggttttt
    38941 ttactgtttt tctacaaatt atgataggat acatagtagg aagaaaggtg acataatttg
    39001 aagtatcagc aagtggaaat agcttttttt attgaccgcc cgaatcggtt tatagcacat
    39061 tgtatgaaaa aagacggaga aataattatt gcgcatgtca aaaatacagg tagaggaaaa
    39121 gaggtcctga taccaggcgc tgaagtggct attgtatttg ctcctggacc taaacggaaa
    39181 accgcctatg atctgattgc tgtaaaaaag aagggtgact ggtttaatat cgatagtcaa
    39241 ttgcctaatc ggctggcaat tgatggtatt ttagacggca cgatcctttt accaggatta
    39301 actggtccat ttacggtata caagcgtgaa gtaacttatc ttcactccaa atttgatatt
    39361 tatttagaga cggtggtcgg acaaaaagca tttgttgaag tcaaaggtat gacacttgaa
    39421 aataaagcga ttggtgcttt tcctgatgcg cccacactca gaggattgaa acatatagga
    39481 gaattaacgt atgccgcaca agatggttat gccgcttatg tcttgtttat tgctcagttc
    39541 gaacatcttc atctggcaac gatccatgaa gaaatgcaac cagcactagc tgatatggtt
    39601 cgacatgcgc agcaaagcgg agttcaaatc ctcgcctata attgtcaagt atcggcagat
    39661 gaggtaactg tcaagcaggc cattccattt gatgtagata tcccttttga agatcctata
    39721 caatagaaag aaggtaaaat aatgatcaac ttaggtatta tcggaacaaa ttggattact
    39781 catcaatttg tccaagcagc tttaagcaca aaaaaatatg aattgacagc ggtatattct
    39841 agacatttgg aaaaagcaca ggaatttggt tctcattatg aaggggatat cgaattcgca
    39901 acagatttga agactttttt caatattact catatggaca ccatttatat tgcttctccg
    39961 aatagtcttc actttagtca agctaagcaa gcaattttgg caggaaaaaa tgtgatagtt
    40021 gaaaagccag ctttttcgac gccaaaagaa atggatgaaa tcatccattt ggcaaatgaa
    40081 cacaatgtgt atttttttga agcagcaaga aatatccatg aatcaggttt taaaaagatt
    40141 gccgattact taccattaaa agacgagata atcggtgcaa atttcagcta tatgaaatat
    40201 tcttcgcgct atgaccaagt attagatgga gaagaaccga atatcttctc gactcatttc
    40261 tcaggtggtg cattgatgga tttaggtgtt taccttgtat atgcagctgt tgcttggttt
    40321 ggaatgccaa aagaagtcca ttatttccca agaaagattt ctactggtgt agatggtctt
    40381 ggatggggga tcttacgtta tgagaatttt gatgtatcga tccagccagg taaaatcggt
    40441 gattcttatt taccgtcaga gatttatttt gactcaggaa cgctagtgat gaatggagtc
    40501 aatgcaattg aacaagcaca atttcatgat cgcgcgcata aagaaatcat tgatttggcg
    40561 gtaacagctg cagaaaatcc aatggcagat gaagcagagg attttgccaa tgtcatggct
    40621 catccgaaag atccagcttg gggattgttg tatgaagagt ggatcgagct agctagaaat
    40681 gtgaaccaag tgatttatga tttaagaaaa aatggcggca tcaaattcga tgcagataat
    40741 gaggaagatt tttaatgaac gaatttgtac aagtatttcc cgaaaattgg cagaaaaaat
    40801 atgaggataa agggtttatc tcaccttctc ttattcaacg agcagttttt cagccactaa
    40861 gtaataaaca aagtatagta gcggtttctc ctacaggttc aggtaaaaca ctggcttatc
    40921 tttggcctct actactaaac gtggaaccag gtgaagcaag tgcgttggtc atttttgctt
    40981 cttctcaaga actagctatt caagtagcag atgttgcacg tgaatgggga aaagacaaag
    41041 agttgaaagt ccaatctttg gtgggcggag ccaacgtcaa acgtcagatt gagggtttga
    41101 aggaaaaacc agaaatcttg attggtacac caggaagaat attggaattg atgaaagcaa
    41161 aaaaaataaa agcacatcaa gtgaaaacaa tggtatttga tgaagcagac cagctatttg
    41221 acgctgggaa cagccaaatc attgatcaaa ttcttcatca agctccaaca gagtatcagc
    41281 tagctttttt ttcagcgaca gcagatcgtt cccttgaaag cattgaaaaa atcactggga
    41341 aaacgtttga gacaattgac gtgacagcag aggacgattc tcgaaaagga ctgagacatt
    41401 actttttacg tgtaccgata cgaaagaaag atgactactt gagacgtctc acgcatatag
    41461 aagattttca tggtctgatt ttctttaatc aactgactga attaggcgta atggaagaaa
    41521 aattgctgta tagaggtgta ccggtaggaa gtctggcctc tgatcagaac aagctactcc
    41581 gaaaagcagc gctagaacaa ttcaaaaaga aaatggtcag agcacttttg accacagatg
    41641 tggcggctag aggtttagat attacaggtc ttccttatgt agtgaatgca gaagttccgt
    41701 taagtgaaga agcttatttg catcgttcgg gaagaactgg tcgaatgggt aatgaaggaa
    41761 tagtaattac actcgtacaa gataataatc taagagattt aaaacggctt ttacgtccat
    41821 caaatataac acttgaagag atttttttat acggaggtaa gctgcaaact gagcagccaa
    41881 ccaaagaaga tgcagctcct gcagtaaata aaaagtatgc gaaaactttt tctggaaagg
    41941 agcagaaccc agaatataac aaagaaaaaa taagaaaaaa agttaaaaat aaatcaaaaa
    42001 aagagagaaa taaaggagca aggcgcaaat aagcgccttt ttatgctatg attatgaaaa
    42061 cgggaacaaa attggttgcc agaggagggg ttatgtgaaa gaacgtcaag aagagatctt
    42121 gcagctattg acagaaaacc aacaaggatt gacagcaagt gatgtagctg agcgcttaac
    42181 tatcgatcga agcaatgcaa gccgatattt aagtgaacta tacaaggccc atcatattgt
    42241 aaaaaccgct ggccgaccag tcgtttactc tttgccaacg gaaaagtcaa aatctgatga
    42301 agtgcatgtc gactcttcta cgcaagtgac ttttgaaaca ctcgttggag aaaatgattc
    42361 tttaaaagtc agcatacagc aggcaaaagc tgcgattctt tatccaccgc gggggttgca
    42421 tacgattatt tttggagaaa ctggtacagg gaagtcgatg tttgctgaat gtatgtatca
    42481 ttttgcaatc gattcagaga tgctttctgc agatgcgcca tttgtttctt tcaattgtgc
    42541 ggattatgct caaaatccgc aactgctctt tggacacatc tttgggatca aaaaaggggc
    42601 ttacacagga gcagctcaag atagtcccgg tctaatagcc aaagcagacg gcggtatatt
    42661 gtttttagat gagatccacc gtttaccgcc ggaagggcag gaaatgctgt ttactttcat
    42721 tgataaaggt atttaccgtc cgcttggaga aagtgcacaa gtacatgaag catctgttca
    42781 gatcattggg gcgacgactg aatcttcaga aagtttctta tctacgttca atcgacggat
    42841 tcctatggca atcaccttgc cgaatcttgc ttcacgttca ctggatgagc gttatgaaat
    42901 catctctctt tttatcaaac aagaagcgaa tcgtttgaat caacgtatcg atatcgaaaa
    42961 agaagcgatt cttgccttca tgctttatga tgcggaagga aatatcggtc aagtgaaacg
    43021 agacttgaaa ctagtctgtg caaaatcttt tttacattac cgtactcatc atgagaaaaa
    43081 gctaatcatt cgaaaagaag aactttccct tcaagtacaa aaaggattac tgaaaatcaa
    43141 ggaaataccg gaacgtctcg accgattcat ggacagcaaa agtcagtatt tgacatttga
    43201 accaggattt gctgatgttg tctggtcaca agatccagaa cgaaacatgc aggtctataa
    43261 cgatattgag gaaaaagtca cttctctttc cgaaaccggt gtggagaaca ttgatctaga
    43321 gaccctcatt tcaaaagatg tggatgctta tttccagaca tatgtcaaag aattgactaa
    43381 aagttcgatt cccaaagatc ttttgccaga tgaaatctgg cggttaacca atcaattgta
    43441 tgatgtggct gaaaaacggt tagaccgtat ttataatgaa aaagctcgtt ttgcttttgc
    43501 tttgcatctg caaagtacat tggatcgtgt gagagaaggt catatgatcg tccacccaga
    43561 tttgaataac gtacggaaaa attttaagag ggaattccag gtagcaatcg atctttcaac
    43621 gatcattgaa gaagaagaac aagttgagat tccttttgat gaaatcggct ttattagtat
    43681 gtttctttct atcaatctag gagaaagtga gcctgttaaa gaaaacaaag tagatgttct
    43741 catattgatg cacggcagac agactgcttc aagcatgttg gagatggcac aagaactatt
    43801 aggaacaaaa gtagggaaag cttttaatat gccactggtt atggaagttc aaacaatgta
    43861 tgaagaagtg ttacaatatg tcaaaaacta tcaagagcat ttgacgaatg gcctactctt
    43921 gttaacagat atgggatcat taaacacctt cagtgatttg atttatgaag agactggcat
    43981 tcggacgaaa gctatcacga tgacaagtac catgattgtg atagaagcga tacggatggc
    44041 aagtgttgga agaagcttag aagatattta tcaaaatatc cagctttcct ttgaatcgat
    44101 cgtacgtgat cagttcaaag cggaaaagtc tgaaacttta cagcgtaaaa aagccgtaat
    44161 cgtgacatgc tttactggtg aaggagtagc tgccaaatta tatcagcgta ttatgccagt
    44221 gattaatcaa aataaggtag aactgatcca gatgcagttt ttagaacgtg aatcattcaa
    44281 aaaacacatc gatgccttat tggaagaata tgagatcaaa gcaattgcgg gaacagttga
    44341 tgttgattat caaaatatcc catttttttc agcctatgac gtttttgatg atgaaaaact
    44401 aaatatttta aagcgtatag ctgatgatga gatcccgaca gctaaaattg tcgattcact
    44461 tgctggatca ttaagcgatg tcttttctat tgatgaactg atccgttcat tgcaaaagac
    44521 agttcagcag atccagaccg atttgtcgat tatcgtggaa cctggagtag atactggaat
    44581 cgttatccat ttagccttca tgttagacgg attgatcaaa caagaaagcc atcggcaatt
    44641 tgagaaactg tctattttct caaaaattta tcgtttggaa atggatatcg ttcgggcaaa
    44701 cttgatggca ctagaacgaa aatatcaggt aaaaattcca gaagatgata tcgcatttct
    44761 tacacaaatg tttcttgaaa ataaaataaa aaaatgaaca cactaatcat actgtttaca
    44821 cactaaacat ctgtgtgcgc actataaaaa agagctaaaa agcatgaaaa cgctatttca
    44881 gctctttttt ttattggcat gcttcttgcg ttatataaaa gtgtaaaaaa ataaaaggag
    44941 tgttaaaaat ggcaaaaaaa acaatcatgt tagtttgttc agcagggatg agtacgagtt
    45001 tattggtcac aaaaatgcaa aaagcagcag aagaaaaagg gatggaagcc gatatttttg
    45061 cggtctctgc ctcagatgca gataataatt tagaatctaa gaatgtcgat gtattattat
    45121 taggtcctca agtacgtttc atgaaagctc aatttgaaca aaaacttgcg cctaaaggta
    45181 ttccattaga tgtcatcaat atgcaagact atggcatgat gaacggagaa aaagttcttg
    45241 cacaagcaga aaatctaatg aaataaatca agtatgcagt tgggggtata acaacgtgga
    45301 agatcaacaa aatctagaag ccatcatggg gttaatcatg tttggcggta atgcaaagag
    45361 cgatgcaatg gaagcgattg cggctgctaa aatcggtgat tttgagttag cggataggaa
    45421 aatcgctgat gcagaagaat cacttataca agcgcatcat gcacaaacag acatgttgac
    45481 acaagaagca caaggaaatc atatgcaagt gacattattg actgttcaca gtcaagatca
    45541 cttaatgaca tctattgcgt ttactgattt agcaaaagaa atcatcgaac tttatcgtcg
    45601 cgtatacagc gaataaatac aacttctttt ttgaacggaa gaagaaaaat ttttgaacgg
    45661 attttttatt ttgttataag gagaactctc tttatataaa aaacttatag gaggaagtaa
    45721 aaaatgaacg gactatcaag ttggatggag aaatacatcc tgccggttgc cgcaaaaatc
    45781 ggagcgcaaa aacatttagt tgctttgcgt gatgctttta tcggcacact gcccgcaaca
    45841 atggcgggat cagtcgctgt aatgatcaat gcaattattc gtgatttacc gcaacagttt
    45901 aacagtacct atgctgacag tttagcagca gacaaaggaa tctttgccgt attgaatgtc
    45961 atcatcggaa tcaatggttt tgtctggaac ggtacactag caatcgccgg attgatcttt
    46021 gccttttctt gggggtataa tcttgcccga gcttatggag taaatgatct agctgggggg
    46081 atcgttggtt tagctacctt gattcaaggt atttcctttg gtccagcatt atcagcagca
    46141 ttagatgtga atgttccttc aaatgtcgca gatgcaatca atagttctga gattggtgca
    46201 acgattgcag atggcacact gtcagttgga ttatggggtt ggctaaaact agatcatttg
    46261 aatggaaacg cttattttac agttatgatc atgggagcta tttcagtcat tattttttgt
    46321 aaattgatgc ttgccaacat tacgatcaaa atgcctgatt cagtaccacc agcagtatct
    46381 aaagcatttg cagccatttt accagcgacg atcgctttat acgtcattgc tattatcaat
    46441 tatatcgtag gtcgtgtagc tgatgggcaa ctgatcattg atttggtgca aaaatatatt
    46501 gcagaaccat tcctaggatt atctcaaggg ttgggagcag tattgatcgt cacagtattt
    46561 gttcaagtat tctggttctt tggtattcat ggaccaaatg tattggcacc agtgctagag
    46621 ggaatctggg gacaagcaca actaatcaat attgatattt tccaaaaagg ttataacgga
    46681 aaaactggta caccagccgt gttagatgca atcgaagatg gaaaagctta tatgtgggtc
    46741 cgcggatcgt tcgatgcttt tgcatggttt ggcggatcag gcggaacgat cgtcttactg
    46801 atagctatct tgattttctc taaacgtgca gattatctaa cagtagctaa attatccatt
    46861 gggcctggta tcttcaatat caacgaacca gtgatgtttg gtctgccaat cgtattgaat
    46921 gcaatcatgt ttatcccatt cttgattgct ccagtagtag caacagcaat tggatggaca
    46981 gctacttatc ttggcctagt cgctccggta tcgcagcaag tcacatgggt agtaccgccg
    47041 ttcttattgt cattcttagc aacaggagcg gattggcggg caccgatcgt aacattagta
    47101 tgtatggtcg tgactttctt gatttgggca ccatttgtca tctctgcaaa caaaatggac
    47161 cctgccgcag gcgaacaaca ataagatgaa cgtgaggagc gggacgcttt aagtttcgtt
    47221 cctcataatg aattttctag gaggaactga aatgattaca attgccagtg caatgcaaca
    47281 agatgaaatc aaagaattgt tagaaggata caatgaagaa ggaatgactt ttacatttaa
    47341 agaaaaacaa ggaatcaagc tgttctttga aacaagtgca gaagatccgg aagttgcggc
    47401 taaaaaagca aaggaactaa tcaaagcaca gccttgggga acagtccttt attttcaatc
    47461 aacagctgtt tagaaaatgg tttaaaaaga taggatggtt gagatgataa aaaacggttt
    47521 atttttatgt agtattggtt ctttgatcgt gttgtatagt ttgaatccac attcgcaaag
    47581 gtatgatttg tatagtatgg tcacaggtct ttttctaaca ggattaggaa tctatttctt
    47641 catgaagggg aaaaaaagag aagaagcaaa ggagaaaaat aactaatgga aatcacgaaa
    47701 aaattaaata ttccagcatc gtttttttac gataaagtta tggactctgt ccttttcgat
    47761 gtacgtaaag cgaccggcaa atcagtaact agaaaacagc tgaaaaattt ggagtacgtc
    47821 aaacaattct cgcaaaataa ccgggctcgc ataaaaatcg aagaagtcat tgaaaaccag
    47881 tcttataagt ttcgtacatc gacaacgaag aatgaattcg tcgttcatta tcaaatcaaa
    47941 ccattggacg attcgacctg tgaggttcat tacacagaaa aaatggagtc ttatggcatg
    48001 cttcaaaagt tgaatgatat gcttttagga acaatcttga tgtattttaa acggagacgt
    48061 ttcaaaaaaa tgctagatat gatcgaagca acgtattaaa tcaatgaaac atggtactat
    48121 ttagttattg aaaaatgaag taagctagaa ggaatttttc ataggaagat agatctttcc
    48181 tgcgaatcct cactagcttt tttgtaggaa ggggcagcaa aatgacaaac aaagtaagag
    48241 agctaggtgt atcttcgatt gaggaaatgt ttgatttagc cacttatgca tttaatgggg
    48301 cagatacacc tgaaaggcga gaacgttttc gtacacttgc ggagaattct tggaattacg
    48361 gattttttga tgaggaggat cggctaacaa gtcaagtcat ggcgacccct tttccagtga
    48421 atttttacgg acaagagtac ctaatggccg gcattggcta tgttgcttct tatccagaag
    48481 caaggggaca aggcgggatc aatcagatca tggaaaagat ccttgaagat tgccgtgatc
    48541 gtaaagtaag cttatcttat ctggcgccat tctcctatcc cttctatcgg cgctatggct
    48601 atgaacaatc atttgataaa atcagttatc aactaaacag tcgtgatgtg ccgtttatca
    48661 aaaaaaaatc tggaaaaata aagcgtatgg attttgaaga tgcaaaagct gcaatcagaa
    48721 gaatttatga acagatgccg gaaaaccaac gagctggtct gaagcgcgaa gactggtggt
    48781 atacgtataa attcaagcaa aaaggcaatt accagtttgc tttgcatttt gatgataatg
    48841 aggaagcaac gggatatatc gtttatcagc ttgcaacgtc ttcctttatt attgcggagt
    48901 ggggattttt ggatcatgat gctttttgca gccttgttcg cttcgtaagt tctcacaatg
    48961 gtgcttttga aacatttgaa tattcatgcg gctacggcgg taatgatcaa aattatctat
    49021 tagaaaatcc atttgcttct gtaatgatca caccttatat gatggcgagg atcgtagata
    49081 tttctttgtt tttggaaaat tatccattta aaaagagaca agctgcattt gccctacaaa
    49141 tagaagaaga tcattatgcg aaatggaatg aaggaatcgt ggaagtaaca atcgaaaatg
    49201 gaaaaaatca tctctcaaaa gtagaacaaa caaaactccc aatcgttcga ggaagtatcc
    49261 aacatatcac gcagctatta ttagggtatc gtaaagtgga agagttggta ttccaagaaa
    49321 gaatacaggt gacaaaagaa tatgaagaaa cgttaagctc aatcttgcca cagcaacagc
    49381 caattcttaa tgactatttt tgataaaaaa cgggtgatga caatattttt gtcaccaccc
    49441 ttttgttttt catttggcat ttgaaggaaa atgttaaagt aaatcctctt ttttcgtaaa
    49501 tttgaatttt ttgttttctt ttgttttagg gttttctttt ttgtggtctt ggattgcttc
    49561 tttcgtaatc ttttcccgat tttttttaga tgaatctaag cgttctgcgt atactttttc
    49621 ttttggctta tcattcattg gaaaggacct ccctacatta tttcattcta cctctagttt
    49681 atcatctgtt aaggactagt ggaaacgttt tgcctaactt ataagctgat ttttttagca
    49741 gataagcttg caagtaaaaa acaaacaagc tacaattgat ttattgaaat tgttcctgta
    49801 gctcagtagg atagagcaat cgcctcctaa gcgataggtc gctggttcaa ttccagtcag
    49861 gaacgtataa ataacccctg tatcctttgc ggtacagggg tttgttttgt atttgtgcca
    49921 aaaatgtgcc aaactagtta tcatttttat ataaactatc gaacacagta ttgatttttt
    49981 ctttatcctg atcttcaagc tctcgaacaa tatgaagata agtagacatt gtagtttcta
    50041 aactgctatg tcctaaacgt ttcgatacgc taagtatatt tactccttga taaagtaaaa
    50101 tagatgcatg tgtatgcctt agtccatgca aagtaaattg cttttcaatc cctaattctt
    50161 ttaatttttt gcgcaaatat ttgctgacgg cgtttgatga aactaatcca ttttttaagt
    50221 tgaaaaaaac aaaattatga gggtttttga tttcaaaatt ctcgaataat tctttttgat
    50281 tgattttaaa cttttttaag agatcaatcg tatgtttatc aatggaaatt ttcctatttg
    50341 aagtttcgtt ttttgttttt ccccattcat ttaatttata attccatgtt ttattaatag
    50401 tgatgatttg atcttcgaaa tcgatatctt cccatgttaa tcctagaagt tcagcaaatc
    50461 gcattccagt ggcaccagca actaacacga gcataggaga agagtactgc gcagaaaggt
    50521 tttcttctac gagtttcatt aaagatttaa attgatcata atctaaatat ttatcttctt
    50581 ttggcttcaa tgaatctttt cctttgatta ctgcttttct agttggatca aacggaatta
    50641 atccttcttc tacggcatct ttcaacgacg ctctaatatg gttattaaac ttaataacgg
    50701 tagattttac atggtcttta gcatacttat ttaaaaagcg ttgatatccc actctatcta
    50761 aatcagaaat caataccgct ggcatatatt tctttatgtt cattaacgta tcttcgtatt
    50821 ttctataagt gataggagat actgttcctt ctttataaag ttgcatccaa tcctcaaagt
    50881 aatctgataa taatagattt ttgcgatccc ctttaaggcc tttgttcaag ttatattcta
    50941 attcgttggc ggcatctttt gcttctcctt ttgtcttaaa tcctgatttt cttatcttcg
    51001 tgtattttcc gtcatctttt ttgtatgaaa tttcgtattg ccaactattt ccacgtttga
    51061 ctaatcttgc cataattgaa tcagctctct ttctctgata caataggaac tataaagaag
    51121 cccattgttt gggttttatt attttttgca catccttttt gcttgccggc gcaaggatgt
    51181 gctatttgtc gttttaatgg tataattgga tgtgtattag atcatccaat cagaggtgtt
    51241 tattatgatt aaagtgattt ttaaaagaat aactgaactt ccagagttta gattatttgt
    51301 tgattattgg tatgtctggt tttttattgt tgcattgctg ataggtctag atgtcatatt
    51361 agaaagaaaa cttaagtaag agttgagtta ataaattgaa ttcctaaatg agatattttg
    51421 tagcccatat tttgtttgcc gacatcacct aatactatgg agctaatcgt tttttctaac
    51481 agaccaaaat cagataatct atttaagcta ccatctatta gctcttgtga atagccagac
    51541 atgctgatat ttccagtgaa attttcgttt ccacgactca ttaagcatgc taacaattga
    51601 atctcaatcg atgttaattg attcagtaca agaagataat actcctcgtt atcccatgaa
    51661 gcgctgttaa ttcgaagtaa acaattctta taaagatttt tatacatatc tattttattt
    51721 tgtgcctttg atttttctac ctcgtcattt atcccttcga atattccaat gagttggtcc
    51781 ttgttctcta agttgaaaac atcttctgga atttgatcgc gaatgttttc taatgattcg
    51841 tttaaatttt tgtagaattt ctcgatgcgt ttgaaacgct tctcgttttt agacccaaaa
    51901 taaagtgact gcacaacgcc accaatataa ggaattgctc caataccgcc ttcaactatt
    51961 aattcaagat attctttttt ggttagtttt tcattgctat tatccatagt tacctcctat
    52021 tttgtcattt cctttacaag cattgtgact cctgatggca ctcttttgta taggttttat
    52081 tattgtgcac aatctaactc ttagtggggc gtggttcatt tattttttac ttactttact
    52141 attaatcata tcccattgag cataggattt ttctatgttc gatcctcttg aactaatttc
    52201 tcctgtaaaa gttactttat cgccctttgt aaaggtatca gcattgttta agtccttcgc
    52261 aaaaattaca tatgaaactt taggtgttgc agaaatatca ttccaacttt tatcatcgta
    52321 ctctttgtct gctataatgg ctattctagt agtcattgat tcgataacag ttccttcaaa
    52381 agtatatgtt ttaccactaa tatatttagt aaaagctgta ttttgctcag tagctggagt
    52441 aatagaataa taactatcta agaaagcacc ccagtcatga ttatttgtct ctaaaaattc
    52501 ttcaaattga gttaggcttt tattgctgct gttagatgta gtagtttgag tatcagatga
    52561 tgagctttcc tgtttgttat tgtcatttgc ctcgtttgat gaggaaagcg agaaacctac
    52621 ggtagtaaaa ataatcccga taataaggag aatcataggt gttttcttat ttgttttttt
    52681 gataaatctt acaattaaca tgattaaacc tataataaat aaaacaatac cagtaaaacc
    52741 aaatataccg tccattaata gatcctcttt ctcttttgat attgaatatt ataaaccaag
    52801 caattctttt ttcttaaaat cgaattcttc ttgattaata atcccttcat ctaacaactc
    52861 tttatacttt ttaatttcat ctgcacttga aatttgtgtt tctttggaat tattatctaa
    52921 tatagattgt tgcttctcta tatatttttt taaattttcc atttcattcc aatatttttt
    52981 tgtaaacata acggtgtttt catctttcgt ggccgctaat atacctccgc gactttcgtt
    53041 tccgcctagc aaggtaaatt gtatataacc attactcata cctggttttt ttaattgtac
    53101 ggctgatata tttttaaagg ggatagtttt ttctccttta ataccttgat taactaaatt
    53161 tataaatcct tttctaataa ttgaaataga atcatcagtt actttaatca aggtttttcc
    53221 tggagatttt attaaaatct ctttttccat tttttcttcc tcatttctgt gatatgattt
    53281 tttttgtaga agctcatata tgaggaaaga gcccgtgttg cagcacgggc ttttttaatg
    53341 ttttgctgaa atcggttttt ttaataattc ttgatgtatt catacatatt gccttgcgta
    53401 agaatatttt ttcttaaaat agcattggca gacagcataa caagtgtatc tgagcttatt
    53461 ctgaatagaa taatactcca taaatttttc gagattaaac tgagattcat cagtcagttc
    53521 gttctcaata tagatattta ataaaattag aatagctatt ttatctgctt ctgtttcaaa
    53581 ttttgagtga aaagttgtag aagtatcgta caaaactgaa aattcaaaat gagaggcgct
    53641 gaaatgtgca agttcatgag ataaatgaaa ggcttctgca gtttcaccgt atagattttc
    53701 attcaaaaaa atgattctgg gttttggata gtagaaacca ggctctttca tctccatata
    53761 aactactttc aaattgtatt cgctcaacat ttctttcaat ttcaaataca tacaaaccat
    53821 cactccaact attcattttc ctctaaagct ttagcaattg caatcgcttt acgcattgtc
    53881 tccttagata tttcttttcc atcaaaagaa aaaacagtat cgtcttctga taaatccaca
    53941 tgtttagggg tttctctttc ttctctacct agaaggtagt ctacagagac atcgaaatag
    54001 tcagcaatcc gacttaattc atctgaatta ggagtattat ttttccactt tgctagataa
    54061 ccgttagaat atccaaaatt aatttctaac tgccgtatag atatcttttt cctcttcgcc
    54121 aagtctttta ttatttcata ggtattcatc gataaaacaa cctttctaaa tgtttacaaa
    54181 aaaagtttag aaaaatacgc agaaataatt tgactaattc tgagtaatga gctatactat
    54241 atcttgtaaa cagatttaac aactaaaaag acaacaaaaa acactattga tatgtaaatg
    54301 cagaccgcca agaaagcttt aaaatcaatg tttttatgtc ttatttaatt atgctcttag
    54361 tatagagtat tactcagata ctgtcaattg aatttagaaa aaagttgtta aatttgttta
    54421 cgaatataaa agaaaggaat gagaaatatg aacacaccgc aaatttttaa tttcgaacaa
    54481 aacgaagttc ggacaatttt agtaaatgat gaaccatatt ttgtaggcaa agacgttgcg
    54541 agtgttttgg gttattcaaa cactaaagat gctttgtcgc ggcatgtaga tttggaagat
    54601 aagatggggt cgcgaatcac gacctcaggt caatcaagag agatgacaat catcaacgaa
    54661 tctggtttgt acagtttaat cttaaaatca aaacttccct ctgccaaaaa atttaaacgt
    54721 tgggtaacaa gtgaagtgtt gccagcaatt agaaaacatg gaggttatct aactccagaa
    54781 aaagtagaag aagctttgct taatccagat acaatcattc aattagcaac tcaactaaaa
    54841 gaagaaagaa ctggaagatt aatcgcagaa caaaagattg cagagtacga acctaaaatc
    54901 tcctatttag atagcatatt atcttctaca gattcagtaa caattagtca gattgcagca
    54961 gattatggga tgtctccaca acagatgaat aaattacttc ataaactagg tattcagaaa
    55021 aaagtcggta accaatggtt attgtgcaaa aaacacatga accaaggata cacaaaatct
    55081 catacaactg agatcccgaa agccgatggt ggcactaaaa ttgtaatgaa taccaaatgg
    55141 acacagaaag ggcgtctatt tatctacgaa ttactaaaaa aagaaggata ttaccctcaa
    55201 atggatttag aggaaattgg ttagaaagga gttttagtat gactgacatt gcagaaatca
    55261 ctcaacgaga tagagaaaaa atcaaagaat atgtcgaaag ttcaaagttc ttaacttaca
    55321 ccatgcttgc tgaaagattt ggaattagca aaagctactt atctttaatt ttaaacggta
    55381 aaaagacttc tgcagaagca aacagaatta tagattcgat tatcactatg tacgaattgt
    55441 aaagggagga acagctaatg caatatctag aagcaaaaat cccaattcca gaaggctatg
    55501 taattatctc ccaagtggat tatgaggagt taaaaaaagc tgatgatact ggtagatgga
    55561 tgacgttgcc agaagtgcta gaacggatta acagaaaata tgattggttt acttctagag
    55621 ttttaaagaa cccaagatat agaaatatta tcgatatcga gaaaaacaaa aatggatttg
    55681 tctattatcc agttgaagga agagacacat atctattttt aagaagtaaa acacttgaat
    55741 ttttagaaac aaatttttcg gaaatcttaa ggaggcaagc ggatgggaaa atttaataga
    55801 gcgctagtgt tcagcgcacc gctaatcatc tacgctttag gactttgggg aagcaggcaa
    55861 gcgttgatag gaacgattgt ttacatggtt tggattttta tggggcttga tgaagctgaa
    55921 gctgagtaca gagcgaaaaa gccaaccgag ggggctgact aaaaatgaat agaaaagaga
    55981 aactagaatg tatattacta ttactcagtt taattctttc actaatttct ctattgggaa
    56041 gtttgtattt ttgatatcaa caattttgtg gatttgggtt ctatttagag taaatatcat
    56101 ttttgtttgg tgattaagga gtttattaaa attaattttc cctacttcaa atgcaaggta
    56161 acaagatata gcacttttag gaggaatatt tagcggtaca gcttcagagt atattctatt
    56221 atcatcgact gatcctcctt tagcaattaa tttcttaaat ggagtagctg accatctgcg
    56281 gtttaagtta gcggatgaaa gttctaaatt aactaacata gctggttctg ttgaatagtt
    56341 agaaatgatt acttttgtat aaatcatatc tgcagcgaag taagaagcat taagttcaac
    56401 ttctagttga gggcgcattc cttttatttt tatccctgtt aaaaacgtac tcaatataaa
    56461 acttattatt gacatccatt gaaaaattgt taagtgaaaa aaattcaaaa taaacaccac
    56521 cagtttttaa ctaaattata ccaaaaagga gagaagaaat aatgcaagaa ttagtaattt
    56581 tgaaaaataa agaagctgtg actacgagct tacaagtggc agaaagcttc gagaaaaaac
    56641 atcaacatgt tttaagagat attgatgcac taaaaaaaga tgtgtccaat tttggacaga
    56701 tgtttgtaga aggtaatgaa ccagattcat atggcagaaa tcgacgagtt ttcttcatta
    56761 gtagagatgg atttttcttg ctggctatgg ggtttacagg aaagaaagct atctacttca
    56821 aacaaaaata cattgaagca ttcaacgaaa tggaagatgt tattcgcaag aatactgttc
    56881 ctcaaacaat tgaagatatg atgatctatc aattagaaga aatgaaagat gttaaaaaag
    56941 atgtttccat gcttaaagat actatgcgaa ttagcggaca acaagagttt gaaattaagc
    57001 aaaaaggaaa tatgaaagtt atgggagttc tagggggaaa agaaagccga gcttatgaag
    57061 aaatcagcaa aaaagtattc tcaaaatttt ggtctgaatt taaacgtacc ttttcaatcc
    57121 caagatatgg cgagttacct cgtaagagat tcgatgatgc tgtttcattt attgaaatgt
    57181 ggttgccaga aactgcgatc cgtatggaaa ttgatcaact gaacagacaa cagagacttt
    57241 ttggtgatga caatgaatag agctgaagcg ctaagaatag ggacggcaat tgctaattgc
    57301 tggtggaaat actataaacc aatcatccta agccaacaac atattgacaa gcaaaaagca
    57361 tggcaacaaa taaaaaagtg actccgccgg caagcaaaga gtcacaaaga aaacacatca
    57421 taaggagatt ttagcatatg gaaaaagaac tttccactct agatcaatat ttgattgatc
    57481 ctgattgggg caagccgaaa attgaggaaa caagtggtcg aaaaatcaga cgaaatcttt
    57541 tgacgaatga agaactagct tgggatcaag atgatttagg caaccatgta actatttggg
    57601 atcatgttta tcttatccat ctatcgaagc attcgaataa acctgaatat atttacgtca
    57661 tcgaagatgg cttgattgat gcgctagaag agtacgacag agataacttg attgatatct
    57721 cttattacgg accaggtaag aaatacattg ctgaaatgga ggcagaattt gatgagtgaa
    57781 atcaaaggga caacgaactt tgaaaaactt tttagtcgta agttaaataa aattctcaag
    57841 aaaaaaggaa attttgatta tttatcttgg gctcacgcgt gggagattat gaaaaagaat
    57901 gatccacagg caacggtaac tattaatgag tacaaacact acagggttgt ttctggaact
    57961 catcaagact ttcttgttga ggaatataaa ccttttctta tggatgaaac tgggacttat
    58021 gtatctgtct cagtaacggt taaaggacac acggaaaccg aattatttcc tgttttagat
    58081 tatcgaaacc aaccagttgt taaaccaaat gcaatgcaaa tcaataactc attgaagcga
    58141 tgctttgtga aagcattggc tctacacgga ctgggattat atgtatttca aggggaagat
    58201 attccaacac cacctagaat cgatacaaag aaattaaaca tgctagagac gattctagaa
    58261 gctttcaatg agcagatggg taaagatatg accaaaacct taatcgaata tgttaatgag
    58321 cagacagata aattagggct cttagctgat aacgttgaaa ctattgaaca gttaagctat
    58381 gagcaatgtg ccttgatgga gcgagcaata gcagctaaga gaaaagaatt agataagaag
    58441 tgatatgagt gtttaaacca ttaatcgatt catattcagc ggttctgaaa aagttcaaag
    58501 gaaaagacat aagcgcaacc atcaatgagg aagtgaacat tgatcgacta aagacgatgt
    58561 atgacggcta cgatggtgat cgagtcattg aaattcgttt tattgatcct agacgtttca
    58621 ccgtacagca acgaaacttc atctatgcgc tgataggcga tatttttatc gatacaggca
    58681 tgccaacgga cttctggaag gaattcttct actttcgttt tgaaggtgtc acagggcgca
    58741 aaataagcct gaaagacgaa tcgaatacaa ctgtgagtga tgccaatgtc ttagcaaata
    58801 tcatcttaga tttcatcttt gaacatcata ttcctttcaa agaaggctat gagattttac
    58861 ctgcgaatca agaatattac ttctacaaat gcatcacaaa aagagtctgc tgcatctgtg
    58921 gcaaaacagg agctgacatc gatcactttg acaaagcgct aggaagacga aagcgcaaag
    58981 aagttgatca tgcagagtac acatttgcag cactctgcag aatccatcac acagagaagc
    59041 acaaaatagg tgtgattaat ttcaaaaata aatatcaaat caaagggatc aaattaaacc
    59101 agaaaacaat caaaaagtta aatattggag ggtaaaaatg acagaacatc gaagttatta
    59161 tgcgattata ccagccaacg taaggtacga caaaagactt aaaccaaata ctaagttgtt
    59221 atacggagag ataacggcct tgtgtaatga aagaggcttt tgttgggcag gcaatgagta
    59281 ctttgcagat ttatatggtg tgaataaaga gaccatatcg cgatgggtaa gtgatttgat
    59341 taagtttgga tacttgaatc gggaaatcat ttacaaagag ggtaccaatc aaataatcaa
    59401 taggtaccta cgaattaatc aataccctat tgacgaaaaa cgcaataccc ctattgacga
    59461 aaaagtcaaa gataataata catctattaa taatacattt aataatacaa aagaatatat
    59521 aagagagtta ccgccttcga aaaaatcgaa ggctaagccc gtccgtcata aatacggaga
    59581 gtataaaaat gttcttttgt cagatgagca gatggagaaa ctcaaaacag aattccctaa
    59641 tgattaccaa gagcgaatcg aacgactgtc agagtattgt gaatcatctg gtaagactta
    59701 taaaaactat ttggcaacta ttcgaagttg ggcaaggaaa gaaaaaagtg aacctaagaa
    59761 cgcaagcagt ggatacaagc gcacaggaag acgagagaag cttcctgaat gggcaatcga
    59821 ccaagaagcc tatctcaaga aaaaagcgct agaacgagct aatagacaat caaaagcacc
    59881 attctaagag gtggaaaaat gaagatcgat tatctagaac taattaatga aatagcgaat
    59941 tataaaaagg gcgaggaatt agacgtcctg agagacgtat atgatcaact cgaagaagct
    60001 ggaattgaag gaattaagaa tgatcgttcg agttggagta aactcagata ctatttcgca
    60061 ctctatatcg atggaacgca attaagaaat ttagcatata ccaaattact attcattgat
    60121 tgtgttaaag gcttgcaaaa acatcttaat gaacttgagc aggtgtaaac aagatggacc
    60181 taaagacatt tacagcacag atcgaattaa tgcatcaaga agctttaaga caaagtgtgt
    60241 cgtacgaaga caagtggctc aacacatttc atggcggacg tgagagcgca cttgatcaag
    60301 tactcaaatt actgaaagga gaatgtcggg atggataaga aagcggcaat gcagcgaatt
    60361 atcgaattga cttattcaga agattggcag gaagataaaa aatagttgca gaagtccaaa
    60421 agctcggtaa atcaatgtgg actgaaaagc ccaaacggag aacgccgaga aagattgcaa
    60481 tctggcatgg tgatcgaatt ctagtaacgg gtaccgctaa acagttatct gaaattactg
    60541 gtctgagcaa aaatattatt tgggatagag ctaggagctt atggattgat tcaaaaggaa
    60601 gacagtttag gtatgtggag gagaaataat ggacgaacta atcgcgaaag tagagcagtg
    60661 ggcaaaagat aagggattgg atcaagcgga tttcagcaag caaatgttaa aaacggtcga
    60721 agaaatcggg gaagttgccg cttctctagc tagaaaagat gaacatggtt taagagacgg
    60781 aattggcgat gtagtagtaa ccttgatcat cttggcaatg caaaatgata tggatttata
    60841 cgagtgcttg gattttgctt atgacgaaat caaaggtcgg actggaaaga tggtcaatgg
    60901 tgttttcgtt aagtccagtg acctgaaata attccattaa tggaagaaat aactgaatag
    60961 gaggatagac atgattgatg caaaacaagt gcaaaaacag aaagatggaa tgttgatgtt
    61021 tgaagcatat gttctaccat ttcttaatca atttgaagtt ttggaatgct ctgccagcgg
    61081 agaagaattg gagtatgttg taattcgtga aaccaaagaa aacgttcaga agctaaacga
    61141 atttctttgc actattaact gttgggatat gatagctcca ggatttttat gtccagctat
    61201 gggagaattt ttggaatatt gtcgtcttga agatgcaggc actttggatt tagcttatct
    61261 ggtatacaac tacctaaaca tcaacacaga tcatttgtgg tttggcactg ccgaaagaaa
    61321 atgggtagtc cgctaaccac caatatcaat gaaaaaaggc ggtttcctga aagtggaatt
    61381 gccgccattg ctgtaaggtt ctttacgcga ctcaaggtca cagaaatata aatgcaaatc
    61441 tcttttgaag tgatccaaag ctctcggaaa atggaagttt tttgtttcaa agaataaatg
    61501 agatttgcgt caagaacctg agagttattt ccaaaaaagc ttccaaagaa ccgaatgagc
    61561 taaggacatc atgtgtaaac acataatata gctctccttt cacggctaat cataacatga
    61621 aaaatattcg atgtcagtag gaaaaaaggt gaattatgaa aagaatatta aattatcccg
    61681 gcagtaacag attctgcaat taaactccga agctgatgta tcagtatcaa ctgtagaata
    61741 ttatgagcgt ggagaaagtc aagcagtcac aaatgtaaaa atcgataacg tcaacggtct
    61801 tatctgttta gatgaaggcg atagtatgaa tgaaattgct gcagaccatg aattatcaga
    61861 aactgcttta attgatcaaa tcgaattagc tagacaatac tttgttccat atgcagatac
    61921 ctggtccaag cataagaatg acatcatttt tccagaggaa caatgagagc aactgatcca
    61981 gtaattatcc ttgaggaagc caaatttatt tggactcacg aagagataga gcaagcacgc
    62041 ttgctctttt ctcaaggagt taagccgagc aaagtagctg aaataatggg tcaaaagatt
    62101 cttgatgtcg gattgctttt gctccatcta gcagaaaaaa atttgatttg aggtgaaaat
    62161 gatgattcaa cttgcaggca tccaaacagg gaaaatttat ttttctggag aaagcaaaag
    62221 cgaagccaac caatggctat tgaaaactta cacgaacaat aagaagctaa ggaaaaaata
    62281 tcctgatttg ttgctaaagg atgatcagat tatgccggaa ccgatgattt tgacccgtaa
    62341 ggagggaagt tgaaactaaa aaaccagccg tgtgggctgg agttgctatt tctttttaat
    62401 aatgagtttt tctaaattta attcattctc acgagtttgc gtccaataat cagaataata
    62461 ttttaattgt ttaagagtag gaatgtcgtc ttcggtaaaa ttagaaaata attctggaga
    62521 attatctttt tttaattgtt ctaatcctga ttctttaaaa cgttgttcaa cgagttttac
    62581 taaattgttg atattcatga taaatcacct ttttaaattt aatttcgatt tgattaatcg
    62641 atacaagtat tatatcaaat aaaaaagctg atttaggggg tcttacaaaa acactaaaat
    62701 tttttcaaaa agaggaggaa cggtggtgaa agtcagagaa caattcaaga tagtgagcga
    62761 cgaagataat gtttacaaaa taaagatcgt taatattaat gaatatcgag aagcagatca
    62821 caaatatttg gttgacttat acatgaacga taaatatttg ggagaaggat tttgtggaga
    62881 ttcacttttt gatgatgagc gaattttgaa ggaggaaaca gaatgatcca cgaactaaaa
    62941 atactaccag aatattttga agcagtgacg agcggacgca aacaattcga gatccgcaag
    63001 aatgatcgtg acttcaaagt tggtgatcag ttaatactac gtgaatataa aaaatacatt
    63061 aaacatgaat tacctggact aacgagacca acatttagtt acactggtga ctcatacaaa
    63121 gcagagatca cttatattac tgattacatg cagaagtccg gatatgtagt gttggggatt
    63181 aaaggggtga attaaatgaa agtatacatc ttagctatca cagagggcac atggatgttc
    63241 ccagtcggtt ccggaaaaat ctataaatca aaaacagctg cttataaagc atttgaaaaa
    63301 tacaaaaaag aaaacggtgg cggcactaac gcaaagattc tagtggctga taactggcat
    63361 gaagaaggtg aacgtaattg atttacctgt tcattttcgt ggtactaact atttttatgc
    63421 tagtaatctt attcaaaaaa agatgagtaa agacgaacga aaaattctgg ccaactttta
    63481 tttagtatta aaaatcgaac aaaatgtgtt ttcggaaagg agaattgtat gggaaaaaca
    63541 aaatcaaaga ttaagaagaa aaaacgacgt ttggaacaaa aggcaatcca gaatggaacg
    63601 gctaagaaaa aataaaaaag ctaccccttt cgagatagca gcgcaatact attctaccat
    63661 aaggggtggc gtttgtgaga tttcattggt taaaagatta ccaagaacta gatgagcaga
    63721 ttctttactt aaagtggaat cttaataaaa gtaagcttga attgaatcga tgggtctgtg
    63781 gtgatttagc aaacgtccgc atcgaaaaga attcgagaac ttcttcttta gaagagaata
    63841 tccaaaagat agaaaatgaa ttggaattgt tgatcgagca aaaagaagaa atgttattgc
    63901 tgatagatag cttttctggt atcgataatc aaattgttaa gatgaaatat gttgatcaaa
    63961 tgagcttaga agatattgct gaatctgttg ggtatagctc atcgtatgtc agacagcgac
    64021 atgcagaaat tagaaagaca ttgaactttt tagatgagta tgaacacaga caagctgacc
    64081 gattgaaaaa agaaaacgaa attgattttt acaatagcga gaagtacaaa gaacaactct
    64141 ctttattcta aaattacact gttcactaaa tgttcggtca ttgtagctat gtaaacattg
    64201 ttagcagcat gatattctat tagtgtcaaa aaaatatgaa agagccaaga tatcccaacc
    64261 gttttattaa ttggtatctg tggctctttt attcttttaa ttagtagttg gcataaagtt
    64321 atttccattt ataaattgat cagctaaatc agcatcataa tcagccgcga taaattgcgc
    64381 tgctgattta ataaatgcat ccatatcatg aacatcttta ttagtatgtc tacgaacata
    64441 gtgcgtttca tcattaccaa tccaagtagc agctttggct aatctttgga gtttaggaaa
    64501 atcattcaaa taattttcaa ttgttttacc taataacatt ttttttattt tatcttcatc
    64561 ctctgaattt ttagatattg cataatcttt aattagaaat tctagagctt ttctataacc
    64621 aactccagca atttgttcca attgctcaga tttagcttgt gtggcttgag tataaatatc
    64681 aacaaatgta ggagaaactt tttcaatatt ttctggtaaa tctattttaa tcggcggacg
    64741 gtaataatct ttaattaaaa tattttcaga atatccttca tcttcattaa acgtatttat
    64801 aaattgtaaa ctataaaatt tgttgcactc atcatttata cactgtacta atacgccaaa
    64861 gattctatca ttatcgaacg cactatatga tgaaacccca aaatacacat acggagtcat
    64921 tatatttccg caatgcggac aactatttgg caaataaatt gtctctgtat tttgacgatc
    64981 acgatactta atattaactt cttgaagcat taaaacacct cgcatctttt ttataaatca
    65041 taccacaaaa tatctgatag gagagtaaac aaatgaatga ttttcatgaa gcggtactta
    65101 gtattgaagt agaatcaagt ttggctaaag tttataagaa agcaattgaa gcagagaata
    65161 gtccgtacag agaaaattgg aatggtaatc atgcacatgt gcaagtggag aatgatgatt
    65221 acagaactgg aatgaatacg ttagttattt ctttattgtc acacactcta cccaatctgc
    65281 aggaaacgat tgaatggtat gagcgaatgg gcgcaaaagt aatccgtaca aattacaaag
    65341 gagagaatta aaatggcaat gatcaaaatt agaacatcca ttagtggaac agagtattgg
    65401 gattcagaaa agaaaaggac agtagttgtt ccgaaagatc aagaaccaaa ttttgaagta
    65461 aaagaagaaa aaggaatttt gagtgatggc aaatcatttg ttgctgtcaa tggcgaactc
    65521 atagctcata gcagtgaaat tcttgatagc gatggaaaca ctgctgctaa ttttgatgga
    65581 gacgaagcta ctaatgatca gtccactgaa gatacggatg aactggacaa tatgactgca
    65641 aaagaattgc gtgcatatgc taagaaacat ggtattgata ttcctggtgc tatccgtgca
    65701 aaaggcgata tcataaatct tattcgtgaa gtagaatgaa atactgtcag tttgacggat
    65761 gcacgaacaa aatagcaaag ggtatctact gtactgaaca caagagatca agcagatcac
    65821 gcaagaagaa gcagcaagca aagtctgttt atcatcatga gaacaaacca ttctatcgaa
    65881 cgcaagcatg gaaagatatg cgtcaattta tttatgaaag agaaggtggt cattgtcagc
    65941 ggtgtggtca gttcatattt ggaaagagag cacacgtcca tcacattgta ccaatcaaag
    66001 acaacgaact gcttaagctt gatccaaaca atctcatgct attatgttca aaatgtcatc
    66061 caattgttga aaacgaaacg gaagacaaaa aagtttttcc ttcgtatttc aattgaagcc
    66121 cccctattca ttttcaaaat tttttcgcgt ggggagatag ggtagcgggg agtcacgcgc
    66181 atcgttaggt caaatttttc aaaaaacaaa ggggggtgta tacaaaaatg acgactaaag
    66241 cgcaacgtaa agcgattatt gatgaaaaag taagtgctga aaaagctcgt atcttagaaa
    66301 taatgaattt gtctgatttg tacaccatca ctcttgatcc attaatcgaa tcatacttgg
    66361 atatttttga aatttaccaa cacaaatatt tattgtggaa ggaaaaagga tttccggaga
    66421 cgcaaaaatt cacgaataaa tcaggagcta ctaatcaatc aaaacatcca ttggcacaac
    66481 aagtagaaac ttgggcagat aagaagatga aagctctaga tttattagga ttaacaaaca
    66541 aagcaaaaac tggtagacta attgctggag gatcgaccgc aagaaaagat gaagaaatta
    66601 cacgcccaga agtaaagcca gtagatgaac tagcagcgca cagaaataaa tggcgtaaga
    66661 aggcaggtgc tgaaaaatga ttgaacctgg tgtaaattat gctgatttat ttgcaaaaga
    66721 agtaagaaag aaacctaaga agtatcctaa gaccgttcgt ttagcaatag atcgctggta
    66781 tcagtggaaa aaaagaaaag atatttggtt tgatgtagat cgcgcgaatg aaatgatgga
    66841 ttgggtagaa tcatttattg ttcacacaaa aggagaaatg gtgggaaaac cgtttctttt
    66901 agaaccctgg gaaaaattta tttattcttg gatttatggt tgggttaaag aaaatgaaaa
    66961 aggccaaatt gtacgcgtta ctcgtgaggc ttatgtccag attccaaaaa agaatggtaa
    67021 aacattgatt gctgtcggtt cattaggata tgcaatgtac ggagaagggg cgttatcagt
    67081 tgattgctat gcttgcgcat ctgattttgc tcaagcgcaa tatgctgcca aaccttttgc
    67141 agttacaatc ttaaacaatc caatcctact tgaaggaact aaaatattta gggggccaaa
    67201 gggaactgtt tctagtatta cttatgacta tattcatgaa gatatggctt actcaaataa
    67261 atttattgtt caaaccaaga atattgataa tatcgaggga tccaatccat attttgtatt
    67321 gaacgatgaa ttgcataaac aggagaaaat ggaacagtat gacaatttta agtctgctca
    67381 gatatcttta ccacagccat tgatgtttaa tatctcaact gctgggaaag gttcgtcgtc
    67441 tgttggaatg cgtgtatatc gcgaagcaaa agaagtgttg aaacgtgatg ataatgattc
    67501 aaactttgtt ctaatctatg agccaaataa aaattatgat tggacggata gaaaagtctg
    67561 ggaaatgtgc aatcctaact ggggaatatc agtcgattta tctgctttag aatcggcatt
    67621 taaaacagcg caacggtcag ctcattccaa agctgaattt ctaacgaaac acttggatgt
    67681 atttgtgaac ggcgcggata atttctttga acaggatcaa gtagagccat gtttagttac
    67741 cacacaagaa cttggtgatt taagtggcga accatgttat atcggtttag atttatcacg
    67801 tacacgagat ttgacctgtg tatctttaaa cttcccaaca tgggatgaag atggtaaagc
    67861 ggttcttaaa gtaaagcaac tttattttat tccgaatgaa gatttagagt ttcgagaaaa
    67921 agaagataat gttccttaca gtgatttggc tgaacaaggt ttcgttgaat tttgcgacgg
    67981 aaaaatgatt gatcaagatc agattttgca gtacatagag gactgcatga atttatatga
    68041 tattcagcaa gtgaattatg atccagcgat gagtgacaaa cttgttgaga aattagaaaa
    68101 cttaggattg gaatgcgttg aagttgctca atatcctaaa gtattgaatg ctccttttga
    68161 cgatgtcgaa cggttgtttt atgagaaacg aattcaattt gataatccat tattccttta
    68221 ttgcactttg aacgttgtag caattactaa catcaatgga caaaaagcgc caagtaaacg
    68281 tcaatcaaag aaaaagattg atgggttcgt ggcgtttttg tgtggtcata aggaaacgat
    68341 gaatcaaatg acagatattg attcagatga gttagatgat tacctaagtt ccatctatag
    68401 ataaatagaa aggcggtgaa aaaaattgaa attacgtgat cggttatcga atgcagtcta
    68461 ttcttttatg gaaaaacgtg gatatatcga ggatattttt ggacactaca cacgttatgg
    68521 tcaaagatat gtgacggatt catctatcat ggaatcttct gatgtttatg aattagttca
    68581 agacatatct aatcaggtgg cattggccac accaattgtt attggtcccg acggcaacga
    68641 agtcaaagat catcacttac taaatatttt gaagagtccc aatgattatt tgacaggatt
    68701 cgaatttacc aaattggaaa caaatacttt attgatcaat ggtgagacat tcccattaac
    68761 ggatagggat cagcttcatt tggcgtacgg tgtaacaact aaaatcaatg aacgacttca
    68821 agaagaattt gaaatgaatg gtcaaaaaat acctggtcaa atgattcgac acattaagaa
    68881 catcggaact gattcattaa aaggtgctgg aataattgat cttgcaagaa acactctaga
    68941 aggcgttctg agcgctgaaa aagttttgac ggacaaatat actaaaggcg gtttacttgc
    69001 gttcatgctt aaactagacg cccacatcaa tccaaataat agcgcccaaa caaaaattgt
    69061 caaagctata ttggatcaac tggaaggaac gcaaaatgag agtgatcatt ctgttaagat
    69121 gattcctttg ggaaaaggat attccatcga gacattaaaa agtcctgttg atgacgcggc
    69181 aattttgaat tatttaggtg tttacaaaaa agacttagga aaatttctag gaatcaatgt
    69241 tgatacgtat caatcgctga tgaagacaga tattgaaaaa gcgatgatgt atctgcacaa
    69301 caaagcaatc aaaccaatat tgaaaaacaa gagcgaacat tacaccgctc ttttttttat
    69361 gcctaattct ggctatagag tggaatggaa aattaatatt ttggattttg ttccttactc
    69421 aacaaaaaca aatattggct acaacatcgt tcgtaccggg attacaagtc cagataacgt
    69481 ggcagaaatg cttggttttc ctaaacagaa tactccagaa acacaagcta tctatatttc
    69541 aaatgactta tctaggattg gccagaaaaa tgcaacagat gattccttac caacgaatga
    69601 tcaagacttg aaaggaggtg atggaaatga agaagaagga aattcgcacg attgacatca
    69661 ccaatctttc aacacgttcc gatgaagaaa ctcatacgag gaccattagc ggctacgctg
    69721 ctgtattcaa cagtcaaaca cttttatggg atgacttaag cgaagtgatt gttcctggtg
    69781 cattctcaaa ggcaattagt aattcggatg ttcgttgttt gttcaatcac gattggtcca
    69841 atgtgctagg acgtactaaa agcggaaccc ttcgccttga agaagatgaa cgtggtttga
    69901 aattcgaagt tgatttaccg gacacaacgg tagcaaggga cttagttaaa tctatggaac
    69961 gaggagacat caaccaatgt agttttggtt ttgtgccgac tgaagaaacg tgggactaca
    70021 attctgaacc aatgcttcga acaatccatg aagtggaatt atacgaggtt tctattgtgc
    70081 ctttgccagc atacgaagat acagaagctg cattaagaag tcgtgatgaa ttagaaaaaa
    70141 acgtcgaaga aagaaaaaaa ttaatcaaaa aaattaatca agcgctagaa gcgtaggagg
    70201 aaaaatacat ggataaagaa ttattgaaaa aaatgaaggc acgtcgtgag caacgattga
    70261 ctgaattacg tgaaaaagtt gaatcaggag aattacgcga agcagattta gaagccgtga
    70321 aagaagaaat tgacagtgtt attgatgaat tgaacggaat taaagacgaa ttaggcgcag
    70381 attctggaac tgatgaaaca gacgacaata cagatgatca atcgaatagt acggattcag
    70441 acgaaagccg ttctggtgaa gacaacgatc aagaagaaga ttcagacagt gaagatagtt
    70501 cagaaaatcg ttctggaatg attactcaac agcaacgaga tggattactt ggatcaatta
    70561 agaacggatt ggaggcacgt gcaaaaatga ccaagaaaca aaaagatcaa caactacgaa
    70621 aagcatttgc taattttgta gctggaaata tttctgaagc agaagctcga gctttaggga
    70681 ttgaagctgg caacggttca gttactgtcc cagaagtaat tgcatctgaa gttattactt
    70741 atgctcaaga agaaaattta cttcgtaaat acggaacagt ggtgcgaaca tcaggagatg
    70801 tcaaatatcc aattcttgtg aagaaagcag atgcgaatgt aaacaagaaa gagcgttcaa
    70861 ctgatattgc tgaaacagct attcagtttg atgaaatttt gcttaatcct gccgaattcg
    70921 atgctttggc aacagtaact aaaaaattat taaaaatgtc tggtgttcca gttgaagata
    70981 ttgttgtgga agaattgaaa aaagcttatg tgcgtaaaga aatcaattat atgttcaatg
    71041 gtgatgacgc tggaaatgaa aatcctggtg cattagccaa aaaggctgta gcatttaaaa
    71101 aacctttaga tctaactgct tcaggtgctg ggcaaaaatt atatgatgca ttaatcgaat
    71161 ttaaaaatac accagtgaca gaagtgatga aaaagggacg ctttattatt aatcgagctg
    71221 ctttgactgc cattgaaaaa atgaaaacag atgatggatt tcctttgttg cggccattca
    71281 cacaagcaga aggtggaatt ggttaccaat tagttggcta tcctgtggat tggacagatg
    71341 cagcagataa aaagggtgaa ccagacacgc cagttttata ttttggcgat ttttctgcat
    71401 ttaaaattca agaagttatt ggtgccttgg aaattcaaaa acttgttgaa aaattctctg
    71461 gtaaaaatca aattggattc caaatttaca acttgctaga tggtcaattg gtttattctc
    71521 catttgaacc ggcagtatat cgctacgaaa ttacaaaacc agttggtggt taagatggaa
    71581 gagcaaacta aagaattgtc tttagaggaa aaattcaaat cacatattca ttttgaagag
    71641 ggcatggatg attctttgct ctctttttat ttaaatatgg caaaagatta tgtcaaaaca
    71701 gcaactggtg gccaacaaga atatcttatt ttgatggttg ccggcattgc ctatgaatat
    71761 agagtttcag aggatgaact cgacaaagct atgaatgcca tgacgccatt tatcgtgcaa
    71821 ggagcgattc aaaatgccga agagacagac caataatctc agatggaaag ccgaattgct
    71881 agacatcaaa acaggaacag acggaaacga tcgtccaact acaatttacg aatttaagcg
    71941 tctaatattc tatgaagaac tcggtgtgac ttctcaagaa aaatatttat cacagcaagc
    72001 caagacagac gttgtcagac gaattaaagt cagatgggat aaatccatca cagagaaatt
    72061 aagtgcgctc aaaattgatt ctgtaacgta taacattact cgcatttata cgaatcccga
    72121 tgcaagagaa atggagttga gtttagctta tgtcgattag ctttgatgaa ttgaaaacag
    72181 cgctgaaatc aacaaagtta gcagtgttca gagacaaagc cagattaggg acgatgtatc
    72241 catacattgt gtactcaaat gtgagtaaca gcaaaaaaat ggcatccggt aaagtctata
    72301 aaaaattacc ttattaccaa gtctcttttt ttacacttgg aacagaacag gatttagttg
    72361 ttattgaaca agcgctgcaa aatgctggca ttccatattc agattttaca ggtatacaag
    72421 gtgatgagaa cgacgatacc gtaaccaact attacacata tgtgaggtgt gtggaaaatg
    72481 ccaagtaata agaatggttt ttctgaaata tcggattatt taggaaacct ttcaaaagtt
    72541 gatccgaaaa aattatcgtt ggaatcttta gaagaagcag ctaactttta tctaaagcag
    72601 ttgcttccta atattcctaa gtcgctctta aaaaagaaac atatgcgcga tcaaataaaa
    72661 gtagtagttg aaaacgatca agtgaaagtt caatttgaag agacggcctt ttactggcgc
    72721 tttgccgaaa atggcacaac aaatcaacgt gcccaacatt ttgcaagtgg tacgtatgaa
    72781 caaaacaaag aaaaaattga agaaattatg actagaaaaa tacttgattt atgggaaggg
    72841 tgattttaat tgggaaaaca agatactttt tattttgaag gattggacga cattttaatt
    72901 gcgatgatgg caacgccaga ttctgttgga actgcaccga cttatagtga agttttacga
    72961 ttgccaattg ccacaaaaat cggtgtcaaa gggaatggaa cagcattaga aaaatgggca
    73021 tccagcaaaa tgtttcgtcg tgtgtcgcga gaaacaaaac atgaacttgc gttggatcac
    73081 gtgggtattc cgatagaagt gatggatgaa atcaaaggat tagttgctaa aagcggagta
    73141 acgtttagca aaaataccgc acgagaattt ccgtacttcg cctttggatt tattggaaat
    73201 attgaaaatg gcggtaaaaa agcagtttgg tatcctaata cacaactatc caatgtgatt
    73261 gacgaagagt atgccactgc agaggaagaa acaaaaattg acgatgtaac tgcaaatctg
    73321 gtttccatcg gactgaaata caataatgtg atgtatgcaa gttttgattc aaatagagac
    73381 ggagcttctc tagaattatt taataaattc attgctcaac ctgtatacga tgaagaacag
    73441 tggaaaacat tggctaaagt tggaggtgcg ggttaatggc tcggttatct gattatggaa
    73501 ttcacgttga agacttaaaa aattctgctg ttgtaattat tcaaggcgca gaattcccta
    73561 tttcatttac tatgcaaacg atggaattta tagcagatgt gtatggtgga gattattcgc
    73621 aatttgaatc tgatatgaac gccatgctat ctaaaaaaga aggacaaatt tcttctgcta
    73681 acttatcgcc tagtgatcta aaaatcatgc gtgccttgat ttatgccatg ctgcgtactg
    73741 gtggtttaga ggaagatcca gaaactattt tcaaattttt gggaatgagt ggagaggtgt
    73801 tgtctgctta tagtacctgt atggaaattt ttgctagcca gacatttcag gtggaagacc
    73861 taaaaaaatc caagaagcca caagactttc aaaaagcgca agcaaaaaga aagaaaaaca
    73921 aaaagaatcg gaagagatag gaactccttg gagtttttat atttacgttg ctctcactct
    73981 attgaattgg agtgagagtt tctttttaaa gtctacacct aacttgtggc tcaaatctta
    74041 tttacagtgg ttacaacaaa acaccgattt tgaaccacct caatctgtaa ctatggataa
    74101 atcgccttgg tggtagaaag gagcgctaag ataaatggct ggtaaagaat ctgatgtcgt
    74161 tcttaatttt aaaacgaatg gcgaagtcag ttattcgaaa acaatcaaag aaatcaacaa
    74221 agaaatgaac ttagccgctg ccgagtacaa aaaccaagtg tctgcgatgg acaaggatgc
    74281 aactcaaaca gaaaaattgc gagcggctaa acaaaaatta gaaaaacaat taggattggc
    74341 tgaacaacga tctcaaatgc tgagagagga atatgaaaaa tctgtcaaag aaaccggtga
    74401 atattctgct gaatcagaaa aactttataa acaattactc aattctgaaa ccggagaaaa
    74461 taaacttcgt acagcattag aacagacgaa cgatgcactt aaagaacaag gtgacgtttc
    74521 tgttgataca gcaaaaaaac tccagaaaat cgaagaaaca ggtgagaaag taaaaggcgt
    74581 tggtgaaaaa atgtctgttg gagtaaccgc gcctattgta gcggcaggag cagcaggact
    74641 tgcagcattt ggtgaagttg acgaggcact tgataccatc attacaaaaa ccggagcaac
    74701 aggtgatcaa gctgatagac tttcacagtc tttcaaaaac gttggttcaa atactcattt
    74761 acctttacaa acggttgggg aagctattgg tgaggtaaat acacaatttg gattcatgga
    74821 taaaaaactg gaagattcaa ccaattatct cctacagtac gctgaaatca atgatacaga
    74881 tgtttcgcaa tcagcaatat ctgctcgaca agctattgat gcttatggac tagaatatga
    74941 tgatttgaat tctgtccttg atgtaacaac gaaaacatcg cagaatactg gtcaatctgt
    75001 agacgacttg atgcaaaaag caattgatgg cgcaccacaa attaaacaat tagggttgag
    75061 ctttggtgaa ggggtcactt tacttggaca atttgagcaa tctggtgttg attcaagcgc
    75121 agctttaagt agtttatcta aagcaacagt ggcttatgcg aaagacggaa aatctttaag
    75181 tcaaggacta gaagaactac aagacaaggt aaaaaatgca ggttctgaaa cagaagccat
    75241 caatgcagca gcagaagtat tcgggactaa aggcggtcct agaatggccg atgcaattcg
    75301 tagaggtact ttgaacctgg aagatttagc aaaaactgct ggagaaagtg ggggagctgt
    75361 aggagacaca ttcgatgcta ctctcgaccc aattgatcaa gccgatcaag ctatgaacaa
    75421 tgcaaaatta gcaatggctg acgtaggtga agcagtccaa gtaagccttt tgcctttttt
    75481 tgaaaaagca acttccttat tacaggaatt ctctaaatgg tgggggtctc tagatcaaga
    75541 tacaaagaat tggatcataa caattgctgg tatagcggca gcagttggac cagtactaat
    75601 cgttcttggt tcacttatgg gatctgttac aaaaatcgtt ggggaagtta aaagttttat
    75661 aggagtttgg caaggacttg ctggtttatt tggaatgtcg ggaggctggt ttgcattagc
    75721 agttatagct attggcgcat tagttactgg actaatttgg gcatataata acgttaaatg
    75781 gtttcatgat ggagtgaatt ctttcttcaa aggtgtttca gatgtagctg ttgaaatatt
    75841 taatttttta agtggttatt ttggtggatt tttcgatggt gttatagcaa atttcaataa
    75901 tttttataat gctggaaaac gaattttcag tggttttcta gattttatca ctggagtatt
    75961 tacagggaat tggtcaaaag catggcaagg tctagttgat atttttggag gtattttcga
    76021 tggtattgtt gctgtaggga aagctcctat taatgccatg attggattga tcaatggatt
    76081 tattggtgga ttgaataata taaagatacc aaaatgggtt cctggtgtag gtggaaaatc
    76141 attttctatt tcaaaactgc cttatttagc acaaggcggt catctaatca atggacaagc
    76201 gattgttggt gaagctggac ctgagttact gactgccaag aatggtaaaa ccacagttac
    76261 tccattatca gacgaagaaa aacgcaaagg gatcagtgga agagtttctg gaggtagcat
    76321 tgaacagcat atacacattg gcaaagtcga tgcaaacaat ccatctgagt tagatcgtat
    76381 gaatcgtaaa tttgctaaag caaacaaaca ggctattcgt gatttgggag gtgttcctat
    76441 ttgagtcgac aatttatgaa tccagatgaa ccaaatttta tttggaaaaa tcggaatgca
    76501 gtaattgata tgaattgcat cattgaggca gagcttccag atattatgcc gaacaagcga
    76561 tacgaaactt acacgattca gggccgaagc ggagaattga cggagacgtt tgatgactat
    76621 gaaccttttg atttggaaat agaagggatc actattccac attcgaaact gagagaagtc
    76681 aaacgatggc tcactggtaa aagccaatta atcacacata atgatccaga caagtatcta
    76741 gaggctatct gcagcatgga taaagaagtc cctttcgaaa acgagtgggg cttcttttat
    76801 acattcgatg ttacttttcg ttgtcagcca ctcaaaagaa aaatcggtga agcacctaaa
    76861 atttttcatt ctagtgttat ggatattttt gatcatggtg acgaaattgc acatccctat
    76921 ctggaaatag aatcgaacgg aggagatata acgatcgctg tcggtgataa aagcctaaca
    76981 atacttaata cgttagctgc aacaatcgtg gttgatactc agcttggaaa agcaatacaa
    77041 gaaggtttga atttatttac gcgtggtgat tggccagtat tgcagcctga atggaatcag
    77101 gtaaaaatat ccggaaaatt taaagaagtg cggttttgga ataggagtgt gtatctgtga
    77161 cgcaagaatt tatttatgct tataaaaaaa tgccagatga tttgagcgtg aacggagcgt
    77221 cgttagttga ttgggaagat ttgccagaaa tcaatcgtgt gctgaatggc caatatcgtt
    77281 tttatggtaa ctattcaaga agcggacagt atcgctctta tttaaaaaaa ggaaatttta
    77341 taaaagcgaa ggtaccagat ggatcatggc aatattttga aatttataat gtcaaaaaga
    77401 atttgacctc cgtttctgta acagctcggc atattggttt tatggccaat aagaacttta
    77461 ttgtcaagtc gtttacggat aacggcaatg ggtctcagat catgaccaat cttaaaaaca
    77521 gtttggcatt tgatcaaaaa tttaactatc tttcgaatgt agggacaacg caccaattta
    77581 cagcaagaca agtcgcgcca gttgaagcaa tcattggttc aaataacggt aatcaaaatt
    77641 tgactggcgt gactagcgcg gaacttgata tggataacta tgatttgaaa ctggtaaaac
    77701 agattggatc agataatggt tttcggattg attttggcat caatttagaa gcaatcgaag
    77761 aagaaattga tgaagaatca attgtcaata gtttgtattt ggttggcggt gttcctgata
    77821 acgattatga tgaagacaaa gaacctatcg aatatggtta tttagaaatt gatggagtaa
    77881 ccaacgagaa tcgacgtatt gccaaacgtg aaaacggaga ttgtaaaaca gttgatgaat
    77941 tgatcaaatg gggcaaaacc ttatttgaca atgatcgtat ccatgagcca aaagctactc
    78001 atacagtcag tatggtggcg ttggaacaca cactcgaata cggtgacatg tatcaagagc
    78061 tagcgtcttt acactttggt gatgtcgctc atgttagggc gaaagagcta gatatcgaga
    78121 taaaagagcg tatggtcgaa tacacttatt tcccaacgct tgggaaatat aaggatattg
    78181 ttttaggtaa tgatttatca ctgtacactt cggcagtaaa tactcaagca caagaattga
    78241 aaaagaaaat cgacaatcga acagaaacgt tagttcaaaa tgtgttgaat gcgacggcat
    78301 ggatcactgg taattctggt gggcatgtcg tttttcgtcc agaaaaagct ccatcagaga
    78361 ttcttatcat ggatactcca aatgtggcga atgcaaagcg agtgtggcgt tggaatttaa
    78421 atggcttagg ttattcagac aacggagtaa atggcccgtt cggtattgct atcacatcaa
    78481 aaggagaaat tgttgctgac ttcatcaaag taggaacaat aaatgcagaa gtattcgaaa
    78541 cttcctttaa tgcttatggt gatgtgttaa aacttgtaaa aggcacgctt caaatttgga
    78601 atgaaaacaa aaaaatcatg gagctaacca aaaaaggtat ggaattctgg aatagaaaag
    78661 aatccattgg aacgatcgga acaacagatt cagcaggaaa tccatttcca aatgctgtaa
    78721 cacctacacc tcttgaggaa aattctttgg taatacgtac aaatggcgat ggaaaataca
    78781 ttttaatttc tccaactgca gaaaaaggat ttgtgttatt aggaaacgga aaagcatatt
    78841 atttcggtga tttagatatt cagggaaaac ttactgttag aggtaaagaa gtgataccag
    78901 gacaaaatgg cggtccatct ggcggaggag aaacacctgg tgggtatcct gatgaattaa
    78961 aaacagatgc agaaaagaga gcttggagaa t
//
LOCUS       DAPBAF010000006        78178 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.006, whole genome shotgun sequence.
ACCESSION   DAPBAF010000006 DAPBAF010000000
VERSION     DAPBAF010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 78178)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 78178)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..78178
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.006"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(1..276)
                     /locus_tag="RD451_000491"
                     /pseudo
     CDS             complement(1..276)
                     /locus_tag="RD451_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
     gene            complement(530..2165)
                     /locus_tag="RD451_000492"
                     /pseudo
     CDS             complement(530..2165)
                     /locus_tag="RD451_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294751.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(2488..2967)
                     /gene="rlmH"
                     /locus_tag="RD451_000493"
     CDS             complement(2488..2967)
                     /gene="rlmH"
                     /locus_tag="RD451_000493"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HDT7565783.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYALAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            3395..4684
                     /locus_tag="RD451_000494"
     CDS             3395..4684
                     /locus_tag="RD451_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HDT7565784.1"
                     /translation="MDRKNVTPKMKKSKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVLMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            complement(4723..5328)
                     /locus_tag="RD451_000495"
     CDS             complement(4723..5328)
                     /locus_tag="RD451_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 domain-containing protein"
                     /protein_id="HDT7565785.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVDSYGMICSARELHLPNAPAKKGILVLPEDAVVGEAFPK"
     gene            complement(5533..5997)
                     /locus_tag="RD451_000496"
     CDS             complement(5533..5997)
                     /locus_tag="RD451_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HDT7565786.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKAVEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKEMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYEIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            complement(6019..6339)
                     /locus_tag="RD451_000497"
     CDS             complement(6019..6339)
                     /locus_tag="RD451_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HDT7565787.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VTKG"
     gene            complement(6483..7562)
                     /gene="pepA"
                     /locus_tag="RD451_000498"
     CDS             complement(6483..7562)
                     /gene="pepA"
                     /locus_tag="RD451_000498"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HDT7565788.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            7762..8112
                     /locus_tag="RD451_000499"
     CDS             7762..8112
                     /locus_tag="RD451_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HDT7565789.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKSSFLKEGAIEGSWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLEISRKKGATD"
     gene            8335..9282
                     /locus_tag="RD451_000500"
     CDS             8335..9282
                     /locus_tag="RD451_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDT7565790.1"
                     /translation="MEQQEKIAVLIPCYNEEATISTVIADFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAVHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVRNTITRMYKTKILDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMFKDYKPLLFFGIWTIFFFLFGLVTGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYHSRK"
     gene            complement(9339..10757)
                     /gene="pepV"
                     /locus_tag="RD451_000501"
     CDS             complement(9339..10757)
                     /gene="pepV"
                     /locus_tag="RD451_000501"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HDT7565791.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
     gene            10906..11751
                     /locus_tag="RD451_000502"
     CDS             10906..11751
                     /locus_tag="RD451_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HDT7565792.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVVWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLAANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAIYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            11755..12195
                     /locus_tag="RD451_000503"
     CDS             11755..12195
                     /locus_tag="RD451_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HDT7565793.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELDQLFQAYASLDDVNS"
     gene            12245..12439
                     /locus_tag="RD451_000504"
     CDS             12245..12439
                     /locus_tag="RD451_000504"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565794.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            12575..13261
                     /locus_tag="RD451_000505"
     CDS             12575..13261
                     /locus_tag="RD451_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDT7565795.1"
                     /translation="MVINNLQQQAYESIRKQIIYSELAPGSKISDKVLEEQLAIGRTP
                     IREALIQLRNQELVKTIPQSGTYVSKIDIRSASLARYTREKLEKPILQECSAKMTKQD
                     QAKLEKILEQTDQAVIAQNKKAFFDLDTDFHRTCYEIAGKREIWDWLESYSTHLNRFR
                     WLRLTISELDWGRVLDEHQTMLQSMIDHNFDEVGFLCTMHLHMIIEEQEYVIHNYPDY
                     FEDIQDRPIK"
     gene            complement(13669..14358)
                     /locus_tag="RD451_000506"
     CDS             complement(13669..14358)
                     /locus_tag="RD451_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565796.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKKIE
                     KRCTEYDLDYK"
     gene            complement(14333..16462)
                     /locus_tag="RD451_000507"
     CDS             complement(14333..16462)
                     /locus_tag="RD451_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HDT7565797.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLLENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKHLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKSIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPQTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            complement(16510..17847)
                     /locus_tag="RD451_000508"
     CDS             complement(16510..17847)
                     /locus_tag="RD451_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HDT7565798.1"
                     /translation="MSDIIIGILLVISFFFMVWYCVKGYNLMVGFAIMATVWMGLALV
                     GNTFSPNPAMEGQGVIDVLTHIYTTGPAEYAKSILVNVFFGAFFGRVLVDSGIAATLI
                     RKVVELGGDKPRITMSLLCIVTAVIFMSMTGIGPVISIAVIVLPILMSLGISVPVALF
                     SFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTYNDYFQIGMIGMIVSLVVVLTVA
                     NISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVLGVVLLDLPIILGFILAGIWALL
                     FTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMTLAMFNNSAAYASPYFSAIFGDW
                     IPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILAVVLAVNPTMSPAFLFPLFAITT
                     IAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGWIIGAILCLITFLLYGNA"
     gene            complement(18099..18458)
                     /gene="rplT"
                     /locus_tag="RD451_000509"
     CDS             complement(18099..18458)
                     /gene="rplT"
                     /locus_tag="RD451_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HDT7565799.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            complement(18511..18711)
                     /gene="rpmI"
                     /locus_tag="RD451_000510"
     CDS             complement(18511..18711)
                     /gene="rpmI"
                     /locus_tag="RD451_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HDT7565800.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            complement(18783..19307)
                     /gene="infC"
                     /locus_tag="RD451_000511"
     CDS             complement(18783..19307)
                     /gene="infC"
                     /locus_tag="RD451_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HDT7565801.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     misc_feature    complement(19351..19476)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            19627..20259
                     /locus_tag="RD451_000512"
     CDS             19627..20259
                     /locus_tag="RD451_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HDT7565802.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGDQSYLDAKN
                     MVLRESHIQKLTMQKTVLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTAIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     gene            complement(20261..21166)
                     /locus_tag="RD451_000513"
     CDS             complement(20261..21166)
                     /locus_tag="RD451_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HDT7565803.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWGIALIISLVLSIWMLIALWRRIR"
     gene            complement(21251..21910)
                     /locus_tag="RD451_000514"
     CDS             complement(21251..21910)
                     /locus_tag="RD451_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HDT7565804.1"
                     /translation="MSVIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFY
                     ANPEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEV
                     RVYDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYD
                     YYKELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVA
                     I"
     gene            22226..23170
                     /gene="mvk"
                     /locus_tag="RD451_000515"
     CDS             22226..23170
                     /gene="mvk"
                     /locus_tag="RD451_000515"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HDT7565805.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            23163..24140
                     /gene="mvaD"
                     /locus_tag="RD451_000516"
     CDS             23163..24140
                     /gene="mvaD"
                     /locus_tag="RD451_000516"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HDT7565806.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKQGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            24153..25238
                     /locus_tag="RD451_000517"
     CDS             24153..25238
                     /locus_tag="RD451_000517"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HDT7565807.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            25235..26299
                     /locus_tag="RD451_000518"
     CDS             25235..26299
                     /locus_tag="RD451_000518"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HDT7565808.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKVPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAKEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(26548..27351)
                     /locus_tag="RD451_000519"
     CDS             complement(26548..27351)
                     /locus_tag="RD451_000519"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HDT7565809.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIPDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(27371..28213)
                     /gene="kduI"
                     /locus_tag="RD451_000520"
     CDS             complement(27371..28213)
                     /gene="kduI"
                     /locus_tag="RD451_000520"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HDT7565810.1"
                     /translation="MQEMETRYTHSPEDIRHYSTEQLRKEFLVEKVFEPGKISLTYTH
                     NDRMIFGGVTPTEKELEITLDKELGVDYFLERRELGVINIGGPGFIEIDGQKEEMKKQ
                     DGYYIGKETRHVVFSSQDAENPAKFYISSVPAHHKYPNVKISIDQVKPMETGEGLTLN
                     ERKIYQYIHPNVCESCQLQMGYTILEPGSAWNTMPCHTHERRMEAYVYFDYANEDTRV
                     FHMMGKPDETKHLVVDNEQAIISPSWSIHSGVGTSNYSFIWAMCGENITYTDMDMVQM
                     DQLK"
     gene            complement(28229..29236)
                     /locus_tag="RD451_000521"
     CDS             complement(28229..29236)
                     /locus_tag="RD451_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HDT7565811.1"
                     /translation="MGKVVTLGEIMLRLSTEQGTRIDSSERFAAHYGGGEANVAISLA
                     NYGHEAIFATKVPDNALGKAVKKHLQCYGVDTKQVLSGGSRLGTYYMETGSGERAASV
                     IYDRAGSSFAEMDHLEWSLEELFQGIDIFHVSGITPALSKKWQKMTKQVIEAAKKAGC
                     LISFDINYRGKLWTQQEASEVIHQLLPLVDICSAGKMDALYLLGIEKAPEAEEQPLIY
                     YYQKMQEKFPNIQVFYSTKRTVHSASENELKGTLWMNHEYVESQVHRITPIVDRVGGG
                     DAFAGGVLHGILSNMSPQEIIDFATAASALKHTIHGDCNQFSQEEVAQFLACGSGKII
                     R"
     gene            complement(29243..29887)
                     /locus_tag="RD451_000522"
     CDS             complement(29243..29887)
                     /locus_tag="RD451_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HDT7565812.1"
                     /translation="MKKIDILSRLKNAGVIAVVRGKSKEEALNACHAIIKGGLTGIEL
                     TFTVPQADQVIKELLSFYKDQPEIVIGAGTVLDAVTARLAILAGAEYIVSPSFDQETA
                     EMCNLYQIPYLPGCMTITEIKTALKSGVDIVKLFPGSAYGPSIISAFKAPMPQVNIMP
                     TGGVSLDNMKEWFDAGVVTVGVGGNLLAPAATGDFDKVTEVAQQYAAKMKEIKR"
     gene            complement(29987..30745)
                     /locus_tag="RD451_000523"
     CDS             complement(29987..30745)
                     /locus_tag="RD451_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HDT7565813.1"
                     /translation="MENKKPYGTVLIKASKILDYLAENQDVSLQTIAKGVGMTSSTVL
                     KILDTLLMIGYVNKNSEKNYRLGAKLIRYANKNIEQIDLVELTLPFLEQLQQKIDETI
                     HLGVLDNNEILYVNKLDPKHQTIRMSSKIGITRPLYNSAMGKAVLAEFSEEQYTDYLE
                     KHPLIPYTEYTITNALRLKKEIKTVKETHIAFDDEEIERDIFCIGASIVKNEQIIGAF
                     SVSMPKYRLTDETKEQIISALKQTKSEIEQRIQK"
     gene            complement(30872..32023)
                     /gene="fucO"
                     /locus_tag="RD451_000524"
     CDS             complement(30872..32023)
                     /gene="fucO"
                     /locus_tag="RD451_000524"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HDT7565814.1"
                     /translation="MSNRMILNETSYFGKGAIESIVPEFQQRGFGKAAVITDKGLIEH
                     GIATKVTELLDKAAIAYALYDGIVPNPTIQNVKDGVAFVKEAEADCLIAIGGGSPIDT
                     AKAIGIILTNPEFSDVISLEGVADTKNPCLPILAIPTTSGTAAEVTINYVITDEVNHR
                     KFVCVDPHDIPIVAFIDSDMMMGMPKKLAASTGMDAMTHAIEGFITKGAWEMTDMLHL
                     KAIEIIGHSLEASVDGDQNGREKMALGQYIAGMGFSNVGLGLVHGMAHPLSAWYNIPH
                     GVACAALLPTVMKYNKEYTGEKYREIALVLGIKGAAEMSLEDVREAACGEIDRLSKAV
                     GIPETISELGVKEADIPAIAEDALRDVCTPGNPRETTVEEIIALYQSLM"
     gene            complement(32105..32416)
                     /gene="rhaM"
                     /locus_tag="RD451_000525"
     CDS             complement(32105..32416)
                     /gene="rhaM"
                     /locus_tag="RD451_000525"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HDT7565815.1"
                     /translation="MVKKAFCMKVYPEKQEEYKKRHDELWPEMRTALREHGVIDYSIY
                     LDPSTSLLFGYLVIEDEKLWEKMANTSINQKWWKYMEDIMETNPDASPVSWELMPVFE
                     L"
     gene            complement(32418..33263)
                     /gene="rhaD"
                     /locus_tag="RD451_000526"
     CDS             complement(32418..33263)
                     /gene="rhaD"
                     /locus_tag="RD451_000526"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HDT7565816.1"
                     /translation="MKKIDILQAPYVKEMIETTSNLYRLGWDERNGGNISYLLKEEEI
                     TPFLDPEKVIRRISMIFDASRLAGCYFIVTGSGRYFKNVASEPAENLGIVRVAEDGKT
                     LELLWGLENECLPTSELPSHFMSHIARLEVDPDNRIVMHCHASHLLAMSFTHELDERS
                     FSRTLWQMCTECLVVFPEGISIIPWMVPGTNEIGEATAEKMKETRLVLWPQHGIYGSG
                     KDMDEVFGLIETAEKAAEVYTYVKAQGPILQTITDENLWHLADAFGVTPKAGYLEEVH
                     TKAGV"
     gene            complement(33277..34533)
                     /gene="rhaA"
                     /locus_tag="RD451_000527"
     CDS             complement(33277..34533)
                     /gene="rhaA"
                     /locus_tag="RD451_000527"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HDT7565817.1"
                     /translation="MNTIERNYEQAKEKYATIGVDTDAVLEKIQDIKISMHCWQGDDV
                     KGFLTPDGELTGGIMATGNFPGAARTPEELRQDLEKAYSLIPGKHKLNLHAIYLDTEE
                     SVDLNEIEPKHFEKWVEWAKKEEIGLDFNPTFFSHPMMKDGFTLAHPDKEVREYWIEH
                     GKRSRKIAEYFGKETGQTSINNFWVPDGMKDNPIDRFTPRERLMESLDEIFTEELDER
                     YVQDAVESKLFGLGAEAYTVGSHEFYMGYGLTRDKLVCLDAGHFHPTEVISNKLSSLA
                     LFSKGIMLHVSRPVRWDSDHVVLMDDELQEIAKELVRNELLEKTNIGLDFFDATINRI
                     AAWVIGTRNTQKALLKAMLEPVERLKEMELAFDFTSRMAYTEELKDFPYADVWNYFCY
                     KNQVPVGLDWLEEVQEYQKDVLELRK"
     gene            complement(34530..35990)
                     /gene="rhaB"
                     /locus_tag="RD451_000528"
     CDS             complement(34530..35990)
                     /gene="rhaB"
                     /locus_tag="RD451_000528"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HDT7565818.1"
                     /translation="MNPTFVAIDIGASSGRLMKSTRDAKGSLILEEVHRFKNGFRNKD
                     GHDRWKIDYLIKEILIGFEKLKQTGIDRLFAGIDTWAVDYCLIDEQGDRINDPIAYRD
                     KRTNGAVEQFSEIYSLDKLYEQTGIQIQPFNTLFQLFAEEKENLAKAHKLLLIPDYLG
                     YVFTGNMVTEKTNASTMQLLNAGTKEWEIELLEKIGVSKELFPPLTEPGTILGDLQKE
                     QFSKYDLPDVTFITVASHDTASAVLGTPGQGERWGYISSGTWSLLGIETKIANVSRNA
                     FSENYTNEWGAHNTVRFLKNIMGMWLIQEVARMQEYEYSYAELAELAAKEKPLQQVME
                     INDPRFLNPPNMIEEIQQYCFETEQPVPVSSGAIARCVYDNLALCYAQELIKVEHLTG
                     TKLEKLHIVGGGSNNRLLNQLTADYAGIIVEAGPSEATAIGNVAMQMLSTGQFSNIEQ
                     ARNVIKQSFPCETFYPDENKQNTMEWYVNKIKGVIV"
     gene            36143..37012
                     /locus_tag="RD451_000529"
     CDS             36143..37012
                     /locus_tag="RD451_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family ligand binding domain-containing
                     protein"
                     /protein_id="HDT7565819.1"
                     /translation="MDYWEKANHSWSEDSKRVILTPTQRSRNLFFYIQEIGYFKAPIP
                     YYTERAHLPSYLIKFTLSGKGSLTYNDNQQQLKAGDLFFIDCQEYQRYQTISEEPWEM
                     DWIHLNGQNVQSFYQEFTKDGHNTFHSTGDPSENKIHHLITELIHMQQGTNARTDFQS
                     SVAIHELLNELILQKYQLDFEEEDIPAYVYKLKQYLDEHFKETITLDQLEQQFLLNKY
                     QLSKDFSKFIGSPPIDYLISKKLSYAKDLLRYTEFTVRMISEEIGIENFAYFSRLFKA
                     KTGLSPRDFRKFS"
     gene            complement(37138..38037)
                     /locus_tag="RD451_000530"
     CDS             complement(37138..38037)
                     /locus_tag="RD451_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7565820.1"
                     /translation="MLQKKISGEQVNTMVSDQYEIYHVKDVVSQNKTIYHHHDFYEIH
                     ATLKGEATFYLNGRQFTIKAGSVLLIHSNDLHRIVRQSSDVFERVYIFVTPSFLESRS
                     TPWSNLSACFQPMGEKRSRVLQIEQEVLKQKLSFIDHPPDKKIYGEDIKYEQALVEYL
                     IFLNQVVQKEESAQEQNAVVPNERVEQMLQYISKNLSHPLSLEEMEKQFFVSKYHITR
                     EFKKYTGFTFHQYVMKKKLIYAKHLLREYRSSSAVYSKSGFSSYPHFLKAFKREFGIT
                     PKEFLKRDTQKQLVHYEHFEDEQ"
     gene            complement(38202..39026)
                     /locus_tag="RD451_000531"
     CDS             complement(38202..39026)
                     /locus_tag="RD451_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HDT7565821.1"
                     /translation="MLNITIRGHDLSEVQTIEDLAEKTKEQGIHTLQLALGLSFPEIP
                     SGANEINSGMGNYVKRVLEKQEVTVGILSCYINMIHPDLTIRQELLTKFEQYLRYASS
                     FGASMVASETGCVLPEIQYTEENFTDEAFAEAVSVIRRLVKAGEKYQMMVGIEPGLNH
                     PVYSLARVEQLIQAVDSDYLGIILDPTNLITSSDYQEQVQLVEEAFERFGEKICAVHL
                     KDFRVEQEKIVPVNLGDGVIEYTKIKEIIMKNRPYLYVVLEETKDDGIRYGRSLLE"
     gene            complement(39037..40332)
                     /locus_tag="RD451_000532"
     CDS             complement(39037..40332)
                     /locus_tag="RD451_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HDT7565822.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGALWALGIMLVAFIVAKKNKYPVVEKGQMAHAGKI
                     IKEAIPSLLLIVIIIGGILTGIFTAVEASAIAVIYSLLIAMFYYKTVKLKDIPNMLFQ
                     SVAMSGTIMFLLATSSMMSFAMAFTGIPQAISSLIMGVTDNKFIILLLVNLVLLLVGM
                     FMDVAPAILIFTPIFLPIVTSVGVDPVHYGLFSIMNLCVGSITPPVGTGLYVGASVGG
                     VKAEAMLKPLLPFYGVILVVLFLITYFPQIVMWLPNMLS"
     gene            complement(40348..40827)
                     /locus_tag="RD451_000533"
     CDS             complement(40348..40827)
                     /locus_tag="RD451_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HDT7565823.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKAHLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            complement(40833..41861)
                     /locus_tag="RD451_000534"
     CDS             complement(40833..41861)
                     /locus_tag="RD451_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HDT7565824.1"
                     /translation="MKKTSLLFAASSLSLGLLGLSGCGNNSSVATVADADVNEIVTLR
                     FAYASNSQPVIDAMNEFGRLVKEKTDGSVQIQYFPDGQLGGERELIELTQSGAVDFTK
                     VSASALESFSKDYSIFSVPYLFNDEEHFFKVMDNEEIMEPIYQSTKNLGFTGLTYYDS
                     GQRSFYMVDGPIHTPEDLKGKKIRVMQSETAIKMVELLGGSPVPMGSDEVYTSLQSNL
                     INGSENNEFVLYTAGHGGVAKYYSYDEHTRVPDIIIMNDAIKEQLTDEQEKAIEEAAK
                     ESTVFEIEAFAKAIEEEKALAQEEHGVQFNDVDNTPFREAVAPLHDIFKNDPTYKDLY
                     QKIQEQGA"
     gene            complement(41878..42984)
                     /locus_tag="RD451_000535"
     CDS             complement(41878..42984)
                     /locus_tag="RD451_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HDT7565825.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            complement(43213..45810)
                     /gene="adhE"
                     /locus_tag="RD451_000536"
                     /gene_synonym="adhC"
     CDS             complement(43213..45810)
                     /gene="adhE"
                     /locus_tag="RD451_000536"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HDT7565826.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            complement(46115..46495)
                     /gene="yajC"
                     /locus_tag="RD451_000537"
     CDS             complement(46115..46495)
                     /gene="yajC"
                     /locus_tag="RD451_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HDT7565827.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            complement(46592..47737)
                     /gene="tgt"
                     /locus_tag="RD451_000538"
     CDS             complement(46592..47737)
                     /gene="tgt"
                     /locus_tag="RD451_000538"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HDT7565828.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            47955..48653
                     /locus_tag="RD451_000539"
     CDS             47955..48653
                     /locus_tag="RD451_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HDT7565829.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            complement(48821..51460)
                     /locus_tag="RD451_000540"
     CDS             complement(48821..51460)
                     /locus_tag="RD451_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HDT7565830.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(52079..53110)
                     /gene="queA"
                     /locus_tag="RD451_000541"
     CDS             complement(52079..53110)
                     /gene="queA"
                     /locus_tag="RD451_000541"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HDT7565831.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            53303..54478
                     /locus_tag="RD451_000542"
     CDS             53303..54478
                     /locus_tag="RD451_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Members of the family are the ATP-binding subunit
                     of ABC transporters for substrates such as betaine,
                     L-proline or other amino acids, choline, carnitine, etc.
                     The substrate specificity is best determined from the
                     substrate-binding subunit, rather than this subunit, as it
                     interacts with the permease subunit and not with substrate
                     directly; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="betaine/proline/choline family ABC transporter
                     ATP-binding protein"
                     /protein_id="HDT7565832.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEAIKLASRIAIMSEGRVIQFD
                     TPENILRHPANDFVEELIGEDRLLQAKPNATRVGEVMLNTAITITPEKSLQEAIKLMR
                     EKRVDTLLVTDNSNVLKGFIDVETLNKKRGKVSSVGDILNKHVFYVKESAYLRDTLQR
                     ILKRGLKYVPVVDEQNKVVGILTRASLVDIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            54482..55123
                     /locus_tag="RD451_000543"
     CDS             54482..55123
                     /locus_tag="RD451_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7565833.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            55120..56037
                     /locus_tag="RD451_000544"
     CDS             55120..56037
                     /locus_tag="RD451_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HDT7565834.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYSFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            56034..56705
                     /locus_tag="RD451_000545"
     CDS             56034..56705
                     /locus_tag="RD451_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7565835.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(57246..57734)
                     /locus_tag="RD451_000546"
     CDS             complement(57246..57734)
                     /locus_tag="RD451_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HDT7565836.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(57935..58201)
                     /locus_tag="RD451_000547"
     CDS             complement(57935..58201)
                     /locus_tag="RD451_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HDT7565837.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(58201..58464)
                     /locus_tag="RD451_000548"
     CDS             complement(58201..58464)
                     /locus_tag="RD451_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HDT7565838.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            58940..59125
                     /locus_tag="RD451_000549"
     CDS             58940..59125
                     /locus_tag="RD451_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDT7565839.1"
                     /translation="MALSYGNKKWSLDEAEIPTYEDTWHLRVEVKEEAENIGGCTLFG
                     KGFGNYDQDIKIKMFYS"
     gene            complement(59267..61090)
                     /locus_tag="RD451_000550"
     CDS             complement(59267..61090)
                     /locus_tag="RD451_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HDT7565840.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(61688..64393)
                     /locus_tag="RD451_000551"
     CDS             complement(61688..64393)
                     /locus_tag="RD451_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HDT7565841.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(64699..65646)
                     /locus_tag="RD451_000552"
     CDS             complement(64699..65646)
                     /locus_tag="RD451_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HDT7565842.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            65836..66105
                     /gene="rpsN"
                     /locus_tag="RD451_000553"
     CDS             65836..66105
                     /gene="rpsN"
                     /locus_tag="RD451_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HDT7565843.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(66281..66643)
                     /locus_tag="RD451_000554"
     CDS             complement(66281..66643)
                     /locus_tag="RD451_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HDT7565844.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(66654..67775)
                     /locus_tag="RD451_000555"
     CDS             complement(66654..67775)
                     /locus_tag="RD451_000555"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HDT7565845.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(67791..68141)
                     /locus_tag="RD451_000556"
     CDS             complement(67791..68141)
                     /locus_tag="RD451_000556"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HDT7565846.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(68271..69782)
                     /locus_tag="RD451_000557"
     CDS             complement(68271..69782)
                     /locus_tag="RD451_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDT7565847.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(70104..71456)
                     /locus_tag="RD451_000558"
     CDS             complement(70104..71456)
                     /locus_tag="RD451_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HDT7565848.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYFEKEKNKLIDAIKQNLEATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(71609..72685)
                     /locus_tag="RD451_000559"
     CDS             complement(71609..72685)
                     /locus_tag="RD451_000559"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HDT7565849.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            72881..74626
                     /locus_tag="RD451_000560"
     CDS             72881..74626
                     /locus_tag="RD451_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HDT7565850.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(74906..75343)
                     /locus_tag="RD451_000561"
     CDS             complement(74906..75343)
                     /locus_tag="RD451_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HDT7565851.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(75327..76700)
                     /locus_tag="RD451_000562"
     CDS             complement(75327..76700)
                     /locus_tag="RD451_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565852.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(77022..77510)
                     /locus_tag="RD451_000563"
     CDS             complement(77022..77510)
                     /locus_tag="RD451_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7565853.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEVFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(77532..78134)
                     /locus_tag="RD451_000564"
     CDS             complement(77532..78134)
                     /locus_tag="RD451_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HDT7565854.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT        22515 a        16639 c        14264 g        24760 t
ORIGIN      
        1 taacatttta cgccatgctc gcttcatttc ttgtgggtat ttaaatggtt tcgcttctgg
       61 atgtttggct ttatatcctt cgtaatcctt actgttgata attgctttca tattaggaat
      121 tggatcttca cctggcatat attgcagatt agaagcatgt aattttttct cagaaacaaa
      181 ccactcattg gaaaagacat gaatcaaatc atcacttact tgtgtaaaat agcgacgttt
      241 aatgacaaag atatcttcat tgctatctag tgtaccttca tttctttgtg cttaaattca
      301 aagataattt tctcaataaa gatttttgat tccagtaaga ttcctttact ccttttacaa
      361 catagcgttg tcctttgttt tgaaacatct tcttcccctc tttgccatta aaaatagccc
      421 aattctctat aaagaagatt aagcttcatt attataatat aaagtttaaa tttggtttat
      481 tacttacttt ttcttattct ctagtaagct aatattgaaa aaaatgtaat cagatcatta
      541 tttttatatg ttgtaacttc ctgataagaa aactaattaa aagaaagagg taactacata
      601 aactaattaa aaaagctaac ttcatagttg gaggataaat ggaagaaact tcaatgattg
      661 tttctccttg tgttccttca atcgacacta gtcctattat caatctctct tttttgtcca
      721 tttacttttg cgactgttcc ccaataatca aatacaggaa gcgttatttt ttgtccttta
      781 gattcatgta ctgtatagac tattttcgaa tccatcactt gataaggcat agtatgccat
      841 tccttgccaa ttcttacttc atgattctgc aaatgttctt tgtattgtaa tgcttccgtg
      901 ggtgcatagt cataaagtcc tccgggaagg agtgtcgtgt aacgaataag attttcttga
      961 ttcattacca agtgatctct ctgagtgaca actttatgtt catagtttgc ttttgttgca
     1021 gcagatacag ccaacagtaa taaaacaatt gccgttatat taactacttt tctttgctta
     1081 gctgatgtgc tcttcatgaa aacgaacgat aaaatcaacg agccaaacag tacttgaaag
     1141 cctaagattc gccaaggaaa ttgaatcatt tgaatgggtg tattttgtaa taaagaccat
     1201 ggaaaaaatt tggtggataa gagccaagag actaccgcac taaggtaaat cactttttct
     1261 ttgcgattaa atcctttaaa aaagaagagt ggacagatca aagaaataat accaatgatt
     1321 cctaccgtaa aggttgtcag gtcattattc atcgcaccaa tcaaactatc cgagacattt
     1381 aatgcttggt gttgtaaggt cgttttatct ggctcattaa tcgattgaac catgatttgt
     1441 cggaacatcg gataccaaaa gtatgctgtt aaaagaatcg tcattcctac tgcctttgac
     1501 aactccacaa tcaaccggat gctttctttt tttcttgttt cacttactac aaagccgcct
     1561 aagactagta agccaacggc tattacactc ataaaagtgg aaagaacatg tgtataaatg
     1621 agtaagctca tactgactgc taatggaatt gcacatggct ttttctcata aatcagtgcg
     1681 taagcataat acataactat cggtataacc gtaagtgcaa tcgcttcagc aatagcagaa
     1741 cgatgataaa tatcaatcgt acggtaccca taaaatgtat ataaacagct aaatataaaa
     1801 gccgcatcga ttctttttaa aaattttagt ccataatgaa acatcagcat gatagtacaa
     1861 acattcaata gccaaacata taagatataa ctaacgatta aattattact tatccaataa
     1921 aaaatgactg ccggaaaaaa ggtcaagtag ggataaaaat aattcactcc gctcccataa
     1981 tgattaaacg tcgtaaaatt gattggacca gaaaaaattg aagataaccc tttgactcta
     2041 gcaaaatgga aggcaatatc ccccgatgta gaaatagtat gaacatttct aaaataattg
     2101 attgaataaa gtccagcaat aattgctagg agaatggaca atattatttt tttctttact
     2161 tgcattactt aattatatac tcctttcatg gattgcttta tctagtataa cttaaatttt
     2221 aaataaatcg ttatttattt ttactctcac ttaaaaaagc actaaaatta taagagaggg
     2281 aggtaatggt ctgaacacca agaattgttc caacatcgaa ttgcttaact aatgagttca
     2341 aagcttaatt atgtggctct tatatttacc gagcgtggat tgcgatctct ttagcgaaac
     2401 aaacatcttt cataaaaaaa acagccatat ccgctttctt ggatatgact atttactact
     2461 actttactat ctttcattct tcttgtctca cttatgataa ggcgcccccg cattgatccg
     2521 gaaggcacgg tagatttgct cgacaaggat cagacgcatc aattgatgtg gatacgtcat
     2581 ttttccaaaa gagatctgag cattgcttct tttcatgacg gcttcgctga gtcctaaaga
     2641 gccgccgata acaaaaacaa ggtggctttt tccttggata cctaattggt cgatttgttt
     2701 agcaaaagat tcacttgtag gatttttccc ttcaattgct aaggcataga cgtattcttg
     2761 ttctttgatt ttcgctaaga tccgttcccc ttctttttct tttacttgtc tcatttgcgc
     2821 ttcgcttaaa ttctccgggg ctttttcgtc aggaacttcg atcaattcga tttttgcata
     2881 ggcattcagc cgtttgacat actcattgat accttggatc aggtattttt cttttaattt
     2941 tcctactgag ataattttga tattcatgtt ttctctcctt tggtcttcat gctcactttg
     3001 tttattataa tcaatttttt cgtctatatg tttattttgg ctatttttgt taaaaagatt
     3061 tccccaacag ttatgcacaa catccacagg tttatccaca gaaaacagtg ttattttacc
     3121 ttatttcatc acattcatta ggcaaacata cgttttataa gaatttatcc actttataca
     3181 caggctgtgg atatgtttta tcccttattt ttccaatcct atccgcgtag ttttacacag
     3241 tatctgtgga aaaagaaaat caaatatttt catctgaaaa caatgatttt tcctaaagtt
     3301 tttcataaaa agttcacagt ctcaaagtag actaaagtca acaaataaga ctatactaac
     3361 agtagataaa tgaatgtaat tggaggagga acacatggat agaaaaaatg tgacaccaaa
     3421 gatgaaaaaa agtaaaaata atagcctctg gcgtaagtta ggtctggggc ttgttggagg
     3481 gatcgttgga ggactactga cagctggcat tttttatgca gcgatgggca ctggcaacaa
     3541 tagttctact gctacaagcg gcaatcagaa ttctgccggt gaaacagttg tggaaaatgt
     3601 caaagtcaat gtagattctg atatcaccaa agcggtagat aaagttcaag acgctgtcgt
     3661 ttctgttatc aacttacaaa gtcaaaacca atcaagcggt tttggcggac tattcgggca
     3721 gcaagaagaa agtagcagct cagatgatag taatttggaa gcttatagtg aaggaagcgg
     3781 cgtgatctac aaaaaagacg ggaatactgc ttatgtagtc acgaataatc acgtagtaga
     3841 tggccagcaa ggtcttgaag tcttgatgaa agacggtacg aaggtaaaag ctgaattagt
     3901 tggaacagat gcttattcag atttagcggt gttgaagatc aattcagaca aagtcgaaac
     3961 agttgcctct tttggtgact caagtgctct gaaggttggt gagcctgcga ttgcgattgg
     4021 ttccccacta ggatctgaat atgcaaattc tgtcacttca ggaatcattt cttccttgaa
     4081 ccgacaagtg acaagtacga atgaatcgaa cgaaacagtc aatatcaatg cgatccaaac
     4141 agatgcagca atcaaccctg gaaattctgg tggtccttta gttaatatcg aaggacaagt
     4201 tatcggtatc aactcaagta agatcgcaag tacttctgaa tctacttcta atgtaagcgt
     4261 agaaggaatg ggatttgcta ttccaagtaa cgatgtagtg aatatcatca atcaactgga
     4321 aaaagacgga aaagtgacac gtccagctct aggtatcaca atggtcgact tatctgccgt
     4381 ttctactcag caacaagaac aaatcttgaa gattccttca tctgtaacta acggtgtcat
     4441 cgtgacaaat gtccaaacag ctacaccggc tgaaaaagct ggattgaaac aatacgacgt
     4501 cattactaag atcgatgaca aagaagtttc ttctggtgta gaacttcaat ctgctttgta
     4561 taagaaaaaa gtgggagatt ctgtcaaaat cacttactat gaaggctcga aagaaaaaac
     4621 aactactgtt gaattgacga tcgatcaatc ggcattaaaa caaaatcaaa atagtgaaaa
     4681 ttaataaaaa agaggttgtg acaaagactt gtcacaacct ctttattttg gaaatgcttc
     4741 tccgactacg gcatcctcag gcaatactaa gattcctttt tttgctggag catttggcaa
     4801 atgcaattca cgagcggaac agatcattcc atagctatct acccctcgca aagttcctgg
     4861 ccagatcatc attccatctg gcatcatagc tcctggtttt gcaacgacaa ctttttgtcc
     4921 agcttcgata ttgggtgcac cgcaaacgat ttgcaatact gtaccattgt ctacttctgt
     4981 ctcagtaatc gataaatggt cagaatcagg atgtgggacg catgttttta cgtacccgac
     5041 aacgatcttc ggttcatgat cagcttcaag ctgttcttcg aatcctgctt ctttgatcaa
     5101 tcgattcaat ttcgctaatt cctcatctgt taagcttact tggccgttcc cttcgattgt
     5161 tagatgatcg gagatatgga aaaagttcca agcaacaact tgaccttgtt catctttgat
     5221 ccgagcaaca ttccatttgc gttcaacagt gttttctgtt cctttatcgt cggctataat
     5281 aaccatcaag gtgtctccga cgtgtgcttt gttataagca aaaatcatgt tctttcctcc
     5341 attatccttt gctgagattt atcttaacaa aaaattgcat tcactgcatg aaattttttt
     5401 catgctttat ttccgaagaa gcctcttctg gaacaccatt tattcgtaac aagggactgt
     5461 gacaagactt ttgtcacagt ccctttactg ttttagttaa ttgattaaaa aggtcgtaca
     5521 agttccactt gcttaattac ttggctgttc ttcttcgtca gaaacgatca agacatcaca
     5581 aggtgaatga cgtatcacgt agctggctac acttcctgtc ataaagcgtt cgactgcatt
     5641 tagacctgac tgcccaacca tgattagatc gatctcatat ttttttggca atttgactgc
     5701 catggattca cgaacagaac catatgcaat aattccttct atatttgtgt aatcaacaga
     5761 tttcccatat tctttacatt cttcgatcat ttccttggct gtttcagttt gctgatcgac
     5821 tagattttga tcaataggtg catagcccat aaagttataa aattgctgat cgattacgtt
     5881 tgctacatat actttcccat tattacggcg agccacttct accgcttttt tgaaagcagc
     5941 aagtgcttgt tcactaccgt cgatacctac taaaatattc ttatattctt gattcatctt
     6001 gacccctcct aacagatgtc agccttttgt tacactttct aggaacgatt cgatttcctg
     6061 ttttgtttta cgatctttat tcactagacg acctaattct tttccgtctt ggatcacgac
     6121 aaaacttggg ataccaaaaa tgttccattc agcggctaca tctatgtact tgtcacggtc
     6181 tacttcaata aattgccaat cagaaaagtc attttcaatt tcaggcattt gcggtttgat
     6241 aaaacggcag tctccgcacc agccggcagt aaagaaaaat acactctttc cagtttctac
     6301 gtagcctgct aattcttcta aactatttgg gataatcatt ctttgtcctc tactttctgt
     6361 ttatgtattt ttcaattaaa ttatacacct ttctttcgaa ctaacaaaca ttgatcctct
     6421 ttttataaaa aaaatctggc aaaaagcaat cttttgccag attttatagt ttcactatcg
     6481 cattattttc cgtatacgat cgtatttact gttgatttat ccaaaccttt cagtgtttga
     6541 atcaacattt ctcgtgcagc ttcaaaatcg cgaatactga acatcgtttg atgcgtatgg
     6601 atataacgtc ccactacgcc aatcactgta cttgggattc cttcgttttg tgtatgagca
     6661 gcacctgcat ctgtaccgcc ttttgaaaca aagtattgat aagggatatt gtttgtttca
     6721 gcgatatcca gcaagtactc gcgcaaacga ggaagcatga tcaaacctgg atcttggata
     6781 cgcatcaatg taccttctcc taaatgtccg aatgtgccat ttttcgtcac tgtatcatct
     6841 gctgcagagc agtctactgc aaagaacaga tctggcttga atttattgac agaagcttta
     6901 gaaccacgca agcctacttc ttcctggaca ttcgcgcctg caatcaatgt atgacctaat
     6961 gtttcatttt gcaacgcttc taaagcttct aataccattg tacagccata gcggttgtcc
     7021 catgatttac tgataatatt ctttccgttg gctgttttga tcgtttcagc gtaaggaacg
     7081 attgtgtctc ctggaaggac accgtaactc attgcctctt ctcttgattc aaacccagca
     7141 tcgaacaaaa tatcggttac ttctactgat ttttgtccgc ttgttcctcg caataaatgt
     7201 gggggaacgg aagaagaaat acatggataa ttcttaccag tagaggtttt aagtgtaaaa
     7261 cgctgagcag aaacaacgta aggattccag ccgcctagag gtacgacttt aaaaagcccg
     7321 ttttcttgga tttgtgtcag catgaatccg acttcatcca tatgtgctgc gaccattaca
     7381 cggggtgcat ccgcttcttc atgatggcgc agaccaaaaa tgccgcccaa accatctaac
     7441 tgtaactcat ctaccagcgg ttccatatga ctttccatat aagcgcgaac atcttgttca
     7501 aaaccgcttg ttccttgtaa ttctgttaac tctttgattc gttgaaatgt tttttcttcc
     7561 atatgctatt cgtctaaatt tcagactaaa ctcctctcag acttatattg atctgcggat
     7621 aaaatatgat tttttctgca gaccgatcgt atttattata gcttattttt tctggtagcg
     7681 gttatttatt tcaaagaaaa tatgagagtg tggtaaaata agcacaagga gtaacaagtg
     7741 agaagaagga ggtatgtcca catgtatgaa gaaagcgaac taagctattt taaaggcggg
     7801 ttagcagttg gaatcggtct aggattattg agcggggtag cttcaacgat ttggtatcat
     7861 cgcaaaaaag tattgtcagc agaccaagta cttgaaaata tcaagtcatc ttttctaaaa
     7921 gaaggtgcaa tcgaaggttc ttggatctct tttgaaaagg aacctattag gaaattcgcc
     7981 gttcggtcga gtgcttatcg gggaggtctt tctcgaatag aagatggcga aactgtttat
     8041 tatgaatttt tagcagatgc tcatacagga accgtattag aaatttcaag aaaaaaaggt
     8101 gcaacagatt aatacgtcaa aaaagtgaga gaacgaatac gcacccacta ttcaaaagag
     8161 aggtatcatg tccttctttt gtagtgggtg gttttttaga tagagctttc caaacatata
     8221 ttccagtatt ttctttttaa ataaatgata tttagcggga aaaactagca tttcctttga
     8281 ttatgaggta tttttaattt agcttttgtt ttctatagtt aaggagagtg aaaaatggaa
     8341 caacaagaaa aaattgctgt tctgattcct tgttacaatg aggaagcaac aatttcaaca
     8401 gtcattgcag actttaaacg agaattacca gaagcagata tttatgtcta tgataataat
     8461 tcgaccgatc gaacatacga attggccgtt caaggtggag caatcgtaaa aaaagaacct
     8521 cgtcaaggaa aaggaaatgt gatccgccaa atgttctttg atatcgatgc cgactattat
     8581 ttaatggtag atggcgatga tacttatcct gcagaagctg tacatggttt gctcgagaaa
     8641 ttacgttctg gtgaagcaga tatggtcatt ggtgatcgcc tatcaaatgg aacctacttt
     8701 gatgagaata agagaccttt ccacgatttt ggaaataacc ttgttagaaa tacaattact
     8761 agaatgtata aaacaaaaat tcttgatgtc atgaccggct atcgaggatt caatcgtatc
     8821 tttgtcaaaa gttttcctat tatgagttct ggttttcaaa tcgaaacgga attgacgatc
     8881 catgctttag ataaaaaatt caagttcgtt gaaatcccaa tcgattatcg tgatcgtcct
     8941 gaaggcagcg aatcaaaatt gaatacattc tctgacggat tcaaagtgat catgatgatt
     9001 attaaaatgt ttaaagatta taagcctttg cttttctttg ggatttggac catcttcttc
     9061 tttttatttg gattggtcac ggggattcct gtgattcgcg aatatatgct gacaagcttt
     9121 attacacgca tcccttctgc gattttaagt actggattga tgactttagc acttctttca
     9181 ttagtaacag ggttgatttt ggatacagtc gtcacgaacg ctaagaaaga atatgaattg
     9241 aatctatatc atgtttatca tgaataccac agtagaaagt aaaaaaagga tcaagactgc
     9301 aaaaataatt tgcaattctt gatcctcttt ttaattaatt atttcgccaa acgatagatg
     9361 gcatctgcat agattgctgt tgctctgaac aagtcatcaa gactcataaa ttcgtttgct
     9421 tgatgcattg tatcagtata tcctgggaac atcgctccat aagcaacgcc acgtttcaac
     9481 aaacgtccgt aagttccgcc accgatgatt tgttcgtagc ctttttctcc agtgtggtct
     9541 tcatagactt gcaataatgt agccaccaat ggatcatcca ttggtacgta atgtggttcc
     9601 attacgcgag cacctcgagt aactgttgcg ccttcttgcc ccactgtttg ttcgatgtca
     9661 ctttgcaatc cgtctactgt tacacctttt ggaaaacgga aattcatatt gatgaagttc
     9721 gcttcctctg taccattttc ttcaaaagca aatagtccag cattcattgt caatttgccc
     9781 attttttcat cttcataagc gactcctagt ttttctccat aaaaatcttc atggacataa
     9841 gcagctgcta catggataaa ttgtttagca gatcctagga attcatagtt atctaagaac
     9901 aatgccaaga aagaacctgc attgatacca gattgtgggc ttgcaccatg tgcgccttta
     9961 ccaactaatt cgatttttac atacgtattg tccgcttcaa tcgttccgct tactggattt
    10021 gcttcgatga attggtaaaa tgcttcttcc atcgcgatag ctgcatctgc acttggtact
    10081 tgaagtgctg cagttgctgt tcctggcacc atattttcgc gaagtccgga aacaaaagat
    10141 ttcaagacat aatctcctgc attgtcgcct ttgaagcgta aagctaaaga aacatttcct
    10201 ttttcaccat tgatgattgg gaattcagca tctggtgaga aaccaaaatc tggttcttct
    10261 tcatgttcga aataataagc catatcgccc cagccgcttt cttcatcgct gccgactacg
    10321 aagcgaactt tttttgatag tttcaagtca agttctttaa tgatcttcat cgcatagtaa
    10381 gctgccatac ttggaccttt gtcatcgctt gatccgcgtg caaagatctt tccatccttg
    10441 attactggtt cataaggatc tgtgtcccag ccatctcctg caggaacgac atccatgtgt
    10501 ccaaatatcc ctagcgtttc gtctccttcg ccaagatcaa tatgccctgc atagttatcg
    10561 acatttttta ctttaaatcc atcacgttcg ccataagcta acatatgttt caatgcgtcg
    10621 cgaggtccag gtccaaatgg tgcatctggt gttacttttg agtcatcgcg ctcgctgttg
    10681 acacgtaaaa gatttttcaa gtcttcaagc aagtcttctt tacgtgcttc tacttctttt
    10741 tgccaatcaa ttgtcataaa gttaatcctc cacttattta agtcttcgtg ttcatgatac
    10801 cacaaattac agaaaaaaat agttcaaaaa atctgacaat tccttttctt atctgttttt
    10861 ctctaaaaaa aatatacgct ataatgagta aaaggaggtt tttagatgct gataaacgaa
    10921 caactagtga aaagagtcat cacacctcgt ccaaaaattt cacataaagg aacatttgga
    10981 cgtatcgttt tgattggcgg caatgaacaa tatggcggag caatcattat gagtgcttta
    11041 gctgccgtac acagcggagc gggtctcacg actgtagtaa ctgatgaaaa aaatcggagt
    11101 gctcttcaca gtcatctgcc agaagcaatg attgtagttt ggacggatac tgaccagttt
    11161 ctttccgtaa taaagcaagc agatgtactc ttgattggtc ccggattggg tacttcttct
    11221 aagagtttgg aacgtttcaa acaagtacta gaaaaccaat caaaagaaca atggctggtg
    11281 attgatggct ctgctttaag tttacttgct gctaatcatc ttttgctacc ctatcccgaa
    11341 caaactgtac ttacacctca tcaaatggag tggcaacggt tgagttctct accgatacaa
    11401 gaacaacggg ataaagaaaa caaaaagaag caacaggaaa tcggtgctgt gctcgttttg
    11461 aaaagtcatg agacaaaaat ttatggtcac cagcacttct acaccaatcc tttaggttct
    11521 gctgctatgg caacgggcgg catgggtgac actttagctg ggatgatcac aggattttta
    11581 gcccagtttc ctcaaaatga ccaaacgatt gcagcagcta tttatcttca tagtttcatt
    11641 ggagaccagc tggcaaaaga acaatatatt gttttgccga cacaaatcag cgaagcactt
    11701 ccgaaatgga tgaattattt ttgtaaaaaa tcaatggaaa acgaggcatg agtcatggag
    11761 aaatttacag gttatgtgcg agaacctttt tattatgaaa cagatcaaat ggggattatt
    11821 catcacagca attatatccg ctggtttgaa gaggctcggg tagccttatt ggtacatcta
    11881 gggtttccct ataaaaaaat cgaagaatct gggatcatca tccccgttct ggaagtaaat
    11941 tgcagctata aagaaatgat ccattacgga gaaaaagtga gcatccatcc aactatccaa
    12001 aagtatacgg ggacacggtt ggattttagc tacgaaattg tgggaactga agacaaaaaa
    12061 ttaaaaacta ctggcagtag taaacactgt tttttacttt ctgattcgca acgattagtg
    12121 aagctgagca aagtcaatcc ggagttagat cagttattcc aagcgtacgc ttctttggat
    12181 gatgtaaatt cttaataaag accgtctaag catttttctt gtattgtgtc gagtagttcg
    12241 tataatgaaa agaaaaaagc aggtgatccc catgtatgtc gttaaagtaa tgcacggtta
    12301 catcgataaa actggctgtc gcactcggga aaaaaactta gacaatctgc tcattttcaa
    12361 agacaaaaaa gaatccgaag cttttgctaa aagaatcggc ggtcgtgtca aaccgatcca
    12421 agaggtacga ccagattgat tcaatatttt tcttttcgag gctctaatag gcatgcctat
    12481 cagggctttt tttgcagact gtgtttttat gcccacacga tttgtaagcg atttatgtta
    12541 taatagatta tatctgcata gaaaggaagg ttaaatggtt atcaataatt tgcaacagca
    12601 agcttatgaa tctatacgta aacaaatcat ttattccgag ttagcacctg gaagtaaaat
    12661 ctccgataaa gtgttagaag aacaactagc tatcgggcgt acaccgattc gagaagcact
    12721 gatccaactg cgcaatcaag agcttgtaaa aaccattcca cagtccggca cttatgtttc
    12781 aaaaatcgat atccgatctg cttcattagc ccgttatacg cgggaaaagt tggaaaaacc
    12841 gatcctgcaa gaatgcagtg cgaaaatgac caagcaagat caagctaaac tagaaaaaat
    12901 actagaacaa accgatcagg cagtaatcgc tcaaaataaa aaagcttttt ttgatttgga
    12961 tactgatttt caccgaactt gttatgaaat tgctggaaaa cgagaaattt gggattggct
    13021 agaaagttat agtacgcact tgaaccgttt cagatggtta cgtttgacga tttcagaatt
    13081 agactggggt cgagtattag atgaacatca gacaatgctt caatcaatga ttgatcataa
    13141 ctttgatgaa gtcggatttc tttgcacgat gcatttacat atgattatcg aggagcaaga
    13201 atacgtgatt cataattacc ccgattattt tgaagatatt caggacagac ccatcaaata
    13261 agaggttttg gaatcagcgt tttgacctga gtattagaga aagaaagggc aaaatagttc
    13321 ctcatatttt gccgtttttt ttgagctaat accgagggtc agctgattgc acaccgttta
    13381 ttgagaggtt gtgaaaaagc tgccctgcat caagtaataa gaacagccaa gtaaaaatag
    13441 cttcttatgt ttttaacttg gctggactta ttaccgcaga tgcaagcttt tgaacaccgt
    13501 tttccaagag gtcgtgagcc tgccgttcat ctccgagtca caaggaacaa tttcaaaaaa
    13561 cagcttctca tgtttgttga atattttgac ttgtgaccga ggagttgaca ggagaacatc
    13621 gtttattcgg aaaaaaagga ctgtgacacg acttttgtca cagtctcttt atttgtaatc
    13681 taaatcatac tccgtacatc ttttttctat tttttttatt tcttctaaga tcccttggct
    13741 acgaatttca ttatatggcc aaagtaagac tgcctctaat acataaggcg aaaaatcgct
    13801 ttgattcatc tcttttgaaa aactcatcgc tgctatctcg ctcaatgcac gaatgtttga
    13861 ttgatgtgta taaaaaggca accgccacag cacaattttt tcgctttgcg tataaattcc
    13921 cttaacagaa gcttcgatgt ggtgaaatag ttcatgtcca ataatcaaag cttgcgctgt
    13981 ttctttagag atcgaagcta gtcctgaaca ttttaatttt tctaacggct ccgtcatcaa
    14041 tcgaatccct tcatcttctg cataagttgc aaaagtgatt cgttcgttta tttgctctga
    14101 ttcacaggaa acgattggaa cagccatttg ttcacaaatt tctcctacat cggcaaaagg
    14161 gtactttttt ttgatgctac atgccgtttc gataccacaa tcgattgatt gttgtataag
    14221 aattttctgc ttggacaaag gaatcttttt ccaaaataaa tctcgccgaa actggtagaa
    14281 tccccaaatt tcttcgggga tctgttgtaa ttcgtttagt aactcttcta acttatgttt
    14341 gtttgatatt tccggcaacg acgatcactt cttcctccgg ttccatagta gatacttcca
    14401 gatccatcaa aagctgtagt tgttccagat ccgtcgctgt aaaatcagag actcttgctc
    14461 ctaagcagag ataaaattct ggtcgggcaa tcaattcagt ttgataaact gccatatctt
    14521 cccaaagttg ttcgacagct gtcatataat tggctgcagt tgttttcata catgaagcat
    14581 gtccacgttg gaccttgata aatccttttt gatcgatgat ccgaagactt ccagcatttt
    14641 ttgaacgatt ctgttcgccg catacataaa agaaaggtgt attttccaat aagcaaactt
    14701 catttttatt taatcgcata tcctctgcag caagctctag tgcttcttct gttgtgatct
    14761 ccttggttag atcggttgct ttcacttccg tagaaccagt agcgatagcc gttacttttg
    14821 aagtctgtgg atcgatttct acgtggactt cgatcgattc tggtgtagcg cctgattcaa
    14881 tcgctttatt catcgcttca tttttcaacg atcgtatatc ttctttactt ggcgaaggga
    14941 tgatacgttc tacaacatct cggaccattg caagtgctac accaatagaa gaaatcactt
    15001 cggcgttttc aggaatcgaa tatttcacac ccattttatt actaaagtaa gtaatcaatg
    15061 aggcagcgcc gccccctaca cctacaagag aaatctgatc tttctccaag tgatacttgt
    15121 ctgccaattc taaaatcacc ggttcaatct tagcatagga tttttccatg atctgttctg
    15181 cgatgtcttc aaccgtcgta tgacaataat cagctaatgc ttggatggct tttcgtgcag
    15241 atgggacatt tccataagaa aaatgttctt cttgcactaa tccaaggaca ttggctgcac
    15301 atgtatttgt aatagtcact tcttctccgt cttccatcac taccttgacg taatcagcag
    15361 ggtctccttc tttaggagag aaaaattcaa ccttaggacc tttgattttt tctgtctccg
    15421 taaatactgc ataatctaga ccggcaatat gtgcagaacg tggaccgaca tcgatgattc
    15481 ctgactgatt agcccgtacc atcgaaccgc ctgccacacc tagaacccga acatctaatg
    15541 aagagatata tgttgggtgg ccacctacaa ttgaataatc gattgctgga cgtccatttt
    15601 taatgacccc gatattggtt gttgttccgc ctacttcaaa ataaacacca ttagacgctc
    15661 tcaagtacat caaagagccc atgactgatg ctgctggacc ggaaagcatg gttaaaacag
    15721 gtcgtttttt catttcattg atttccatta ctccgccgtc tccgcgcata atcatcaaag
    15781 aaacattgac ccctgcttct cgtacggaat cttctgtaga ggttgccgta tctagcattt
    15841 ttggtaaaat agatgcattg attgctgctg tccgagttct tcttgtcaat ccatataatt
    15901 ttgtgatgtc agaagccatc gttgtaggga tcgattttac cgatgctgct tcataaacaa
    15961 ctcgttctgg ttccccatta tctactccaa atgccataga agaaaccaag acctccgctc
    16021 tttctctttc taaagaagaa atcgtttctg aaacacggtc tacatttaag tgtttgacag
    16081 gtaagaatgc attgacaatc tctatttttt tcttattccc taaatcgata tcgttcaatc
    16141 tagtttgtcg ttttgctaaa aaaccttcta atccaccttt tgccatcccg attacgccga
    16201 cttttgctac gtctccttca atcagtgcat tagtcgcttg tgtggtagaa tgtgcaacaa
    16261 acacaacatc ttctggactg atattatttt ccagcaaaca attttgaaaa gactgaacga
    16321 cacctgcggc tactccacgg acatcatcgt gggttgtttt cactgaagat tttccgatga
    16381 tttcgtgcgt cgcattatcg attgcgactg ctttcgtatg tgtaccgcca acatcaattc
    16441 ccattcgcac aaaacgtttc attttctttt cctccattca tctaatcgtt tttatcgacg
    16501 ttttgtttac taggcgttcc cgtacaataa gaacgtgatc aggcataaga tcgctccgat
    16561 gatccaacca gttgggatgg atttcttcat atattctcga gaagttactt ttgtataacc
    16621 taatccccaa gcaacccaag attgtgtaat atctaaatgc tgaggagcaa tcgttgtgat
    16681 tgcaaataac gggaacaaaa aggctggcga catcgttgga ttaacagcta atacgacagc
    16741 taaaatagct gagcctgaac cgactagatt cattggaccg cggaaaaatc ctagtggtgt
    16801 caatatagca aatacgattg ccaagactaa tggtgattgc ggtatccaat ctccaaaaat
    16861 agctgaaaaa taaggagaag catacgcagc tgaattattg aacatcgcta aggtcatcaa
    16921 gaaaccaacc attggcgcaa catctactgc gccatctgta aataatttcg caaactgacg
    16981 acagatttct ttataacctc cgcgcaattt tccagtaaac agcaatgccc agatacctgc
    17041 tagaataaaa cctaagatga ttggaagatc taaaagaacg acccctaaaa ctggtaataa
    17101 tacggctaac catgagatca ttggtgcgtc gccaccttca gctggtacgt ttgctgccat
    17161 tgcatagcgt ttctttttgt tcattgatat attagcgacc gttagtacca caactaagct
    17221 tacaatcatc ccaatcatac caatttggaa atagtcatta taagtatagc tttcagccgc
    17281 tggattgaaa ccagcataaa tcgtttgata ttgtttgaaa ttgacgatat tagcaaagat
    17341 tccagccata atcgagccca taaatgagaa cagtgcaacc ggtactgaaa tacctaatga
    17401 catcaagatt ggcaacacaa taactgcaat agaaatcact ggtccgattc ctgtcatcga
    17461 catgaatata acagcggtta caatacatag taagctcatc gtgattcttg gcttgtcccc
    17521 tccaagttca actacctttc gaatcagggt agctgcgatt ccgctatcta ctagaacacg
    17581 cccgaaaaag gcaccaaaga agacatttac caagatcgat ttggcgtact cagctggccc
    17641 cgtcgtatag atatgcgtca acacatcaat tactccttgc ccttccatcg ccgggtttgg
    17701 tgaaaacgtg tttccgacta gcgctaatcc catccataca gtagccatga tggcaaagcc
    17761 gaccatcaag ttgtagcctt ttacacagta ccagaccatg aaaaagaatg agataactaa
    17821 caaaatacca ataataatat cactcatgtt attcctccgt ccattttgtt tttctgataa
    17881 gcaaactaat atatcagtca aactcattct aacttatgta gttagcgctt tcattaaagg
    17941 gtgaccataa atgttcagtt ttcaattaaa aaaccttaat tatgctattt tagacttata
    18001 cgttattgtc ctgtttcatt tgatggagga ttgtaaataa aaaaagagga aagaacataa
    18061 cttttcgtta tcttctttcc tctttataat tgtttagctt atttagccaa agcttctttt
    18121 gcttggtcag ccaatgcagt aaatgctgct gcatcgttaa cagccaagtc agctaacatt
    18181 ttacggttga tgtcgatttc agcaactttc aaaccgtgca ttaattttga gtagctcaag
    18241 ccattcatac gagctgctgc gttgatacga gcaatccaca atttacggaa gtcgcgtttc
    18301 ttttgacgac gatcgcgata tgcgtagttg tatgaattca ttacttgttc ttttgctgtt
    18361 ttaaataaag tgtgttttga accgtagtaa ccttttgcta attttagcac tcttttacga
    18421 cgtttacgag ttactgttcc acctttaaca cgtgccatgt ataattcctc ctaataaaaa
    18481 taaatcttca gattctgtta tttgtacttc ttatttcatt tttgctagtt gttggcgaat
    18541 acgtttgaag tcgccactag aaaccatgct tgctttacgc aattgacggc gttgtttttt
    18601 tgttttgccg tggaaacggt gacttgtaaa cgcgcggaag cgtttcaatc cgcctttacc
    18661 agtacgtttg aaacgttttg ctgatccgcg gtgtgttttt tgttttggca tgactatatt
    18721 tcctcctcaa aatctttcgt tatccgacta tcggctgtcc aacagccagt tagtcattca
    18781 aattacttac tgtcgttttt cggtgccagc gtcaagaaca tgctgcgtcc gtccattttc
    18841 gctttttgtt ccactgttgc aatatccgca gtttcttcag ctaagcgatt caagactttt
    18901 tgaccaattt ctttatgggt aatggcacgg cctttgaaac ggatagaagc tttcacttta
    18961 tcgccctttt ccaagaactt acgtgcatta cgaagttttg tattgaagtc attcaagtcg
    19021 atcgtaggac ttaagcgaac ttcttttaca ttgatcactt tttgtttttt acgcgcttcg
    19081 cggtctttct tttgttgttc gaaacggtat ttaccgtagt ccatgattcg cgcaactggt
    19141 ggtttcgcac caggggcaac taacacaaga tccaagtttg cttgttctgc aatattcaat
    19201 gcttctgctt ttgtcttaac tcctaattgc tcaccatctg aaccgatcaa tcgtaactct
    19261 cgtgcacgaa tgccgtcgtt aaccatcata tcctttgcta tggtcattca cctccaaata
    19321 ttatgagaga aagaaaagct taccgaataa acggcaataa aaaaacgagt tctcttacag
    19381 aacccgcgcg tacttcacct aatagaacca gtgaaaacta tctagcccag tgacattatc
    19441 aactaaggcg agaagcgggt gcttctgctt ttatttctca accatcatag tatagcaaaa
    19501 actaatcttt ttgtcaatgt ttttcataca gtttgtcttc cttttctgaa aatgattaga
    19561 ttagcagact ttctagcagt gattcccgct tctttgctat actaaagaaa aacgaggtga
    19621 acccacatga aaaaaatcga acctattcca ccttctcttc ctcttcttac aaagggagag
    19681 ttttatttag aagatgagga gatcttctct ggtcttctga tcaacggggg tgaccaaagc
    19741 tatctcgatg ccaaaaatat ggtattaaga gagagtcata tccaaaaact tacgatgcaa
    19801 aaaacagttt tacgtcattt tgaatgcagt aatgtcattt ttgaaaaatg tgatttttcc
    19861 aatctggagt ggattggtgg cagtttccac caagtcgtgt ttcatcaatg taaattaaca
    19921 ggtacgaatt ttgccgaaag ttatcttcga gactgtactt tcactgattg tattgcttcg
    19981 atggcttcct ttagtagtac aaacttgaaa gctgtctcct tcgatcattg tcaattagaa
    20041 gacagcgaat tttatgaggt cacttggaaa aacctttttt tgtctgacaa tcagttgacc
    20101 ggttcgaact ggtttcgaac ttctctgaag ggattagact ttacgactaa tttcttcaca
    20161 gcaatcgctt tatctcaaga ttctttggcg ggactaatcg tcaaccaaga gcaagcactt
    20221 gtgatcgccc aagcccttgg tttgcagatc aaagactaga tcaacgaatc cgccgccaca
    20281 gtgcaataag catccaaata gataagacca aactgatgat caaggcgatt ccccatccga
    20341 aaacggaatg ggtaaagggt aactggagat tcattccgaa gaatcctgtc acaatagttg
    20401 gaacggtcaa gatcagcgac cagaccgtca aaaatttcat cgtgtcattc aagttgttat
    20461 tcagcaaatt attataagtg ccagagagct ggtctaaaat ctgcgaagct aagttcgtca
    20521 tttcaactgc ttgtcgtgct tcgatcagcg catcgtccaa ctcttctttt tccttttctg
    20581 acaacttgcg ataaatagcc aatgccttga tttgttctaa aagtactaca ttttgttttg
    20641 ttcctgtaac taagtaaacc aaaccgatct ctaaatctga aagttgcagc agattcttgt
    20701 tcgttgtttt ttctcttaat ttcagattaa gccgctgacg ttcactattc acttcctcga
    20761 ttaaaggaaa aaaggaatca gaaatcaaaa acaatgtacg aaacaataaa ctgtatacac
    20821 tcatgtctgg cattcgttcc aaaagcgatc gaattagtcg aatcacgtac tcggtattcg
    20881 gcgtggtaaa tgtaaacaaa ccgtcttctt ttaaaataaa agcgatagga ctagtttcat
    20941 aatgattatc gactttttgc tggtgcggaa catttgatac aagcagtaac gcttcatcaa
    21001 aagaatcgta ctctacgcgc gcccgttcat ttttatctag agaataagtc agcatctcgt
    21061 cactaatgcc atattcttct tttaagtttt taacagctag cacatcgttt tgctgtacat
    21121 tgatccaaaa attacggtct tgattaaaat agtgtttttc ccgcatactc tatcctcctg
    21181 acatttgttt ccagtataaa gaaaaaagtc gctcaaataa aggtttaccc tttatttgag
    21241 caactgtaaa tcaaatggct actttggttt ggcgaatctc tgctaatttt tcttcgatca
    21301 ttttcaagac ttcttctttt gcttgaggat cttccacaaa attatagcgg tctccatcga
    21361 tttggatttt tggactttct ttgtattctt cataccattg atcgtaacgt ctgttcaatt
    21421 ctttgtaata atcgtataga cttggatcaa aggacaattg ttcatacgaa cgaccacgtt
    21481 tttcgatacg ctccaacatc gtatcaaaag atacacgaat atgaactaat aaatccggat
    21541 gttttttatg ggcagcatag ggaagttctt ccatcatgtt ttccagcagt tcatcataca
    21601 cacgaacttc tgtttctgtt gctcttccta gatctgcatt tagatggaaa agcagtgaat
    21661 cttcataaat cgaacggtcc aatacattat tgtcatcttt cattgcttgt ttgatgcttg
    21721 caaaacgttt attcaaaaaa taaatttgca gcaaaaaagc atactgttca gggtttgcat
    21781 aaaataaggg caagacttca ttatcatcaa tcgattcata aaatgcctga ctatcaaagt
    21841 gttcagccat catttctgtt aaacttgatt ttccggcacc aattgtacct gctaaaacga
    21901 tcacgctcat ttacctccag ctcacttcat cactaaatat tgtgtttaac tccaaccttt
    21961 ttaaatatac ccccaatatc tagtagtgtc aattgtattt ttttctagtc aaagaagaaa
    22021 aaaagtcaaa aaattcttaa gaaaaaagtg ttttttcttt agaaaacgta ttcttagttt
    22081 tacttctgag atggttttag taaaataaag gaggaatgtt ttttgagacc cttagtggac
    22141 aaaaaaattc gtgaagcagc gcaactcgtt ttgggcgctt tattttttgc ttaaaaatca
    22201 cttttacgtg agaaggagtt agattatggc aaactatggc caaggagaat caagcggaaa
    22261 gatcatattg atgggcgagc acgcggttgt ttatggagaa ccagcgattg cctttccttt
    22321 ctatgcaaca aaagtcaccg cattccttga agagctggat gcaatggacg atcaactggt
    22381 ttcttcctac tattcaggaa atttagccga agctcctcat gcattaaaaa atatcaaaaa
    22441 attattcatt cacttaaaaa aacagcatga catccaaaaa aacttgcaac tgaccattga
    22501 aagcacgatt cctgctgaac gtggaatggg atcaagcgct gcagtcgcca cagcagtcac
    22561 tcgtgctttt tatgattact tagcatttcc tttgtctcgt gaaatactat tagaaaatgt
    22621 ccagctttcg gaaaaaatcg cccatggtaa tcctagtgga atcgatgcag ccgctactag
    22681 cagcttgcag ccgatttatt ttacaaaagg gcatcctttc gactactttt ctttgaacat
    22741 cgatgctttt ttgattgtcg ctgatacagg aatcaaagga caaacaagag aagccgtcaa
    22801 agatgtcgct cacctctttg aaacccagcc tcatgaaact ggacaaatga tccaaaaatt
    22861 aggatacttg acgaagcaag caaaacaagc aatcattgaa aattcaccag aaacgttggc
    22921 acagacaatg gatgaatcac aatcacttct ggaaaagctg acaatcagca atgattttct
    22981 taatctattg atccaaacag caaaagatac cggggcattg ggtgccaaat taactggcgg
    23041 tggacgcggt ggctgtatga ttgcattagc acaaacaaaa acaaaagccc aagaaatcag
    23101 tcaagcactt gaagatgcgg gtgctgctga aacttggata caaggattag gagtacatac
    23161 ctatgtttaa aggcaaagca cgcgcatata ccaacattgc tctaatcaaa tattggggta
    23221 agaaaaatga agaactcatc cttccaatga acaacagcct ttcgttaaca ttggatgcat
    23281 tttatacaga gacagaagtc atcttttctg atagctatat ggtagatgaa ttttatctag
    23341 atggcacctt gcaagacgaa aaagcaacaa aaaaagtcag tcagtttctt gacctttttc
    23401 gtaaagaagc cggcctctca ctaaaagctt cagtaatcag tcagaatttc gttcctaccg
    23461 cagctggatt agcctcctct gccagcgggc tagctgcttt agcaggcgct tgcaatactg
    23521 ctcttaagct tggattagat gatctctctc tttcaagatt tgctcgacgc gggtctggtt
    23581 cagcttgccg aagtattttc ggtggtttcg tcgaatggga aaaaggccat gacgacttaa
    23641 gttcttacgc taagccagtc ccttccgatt ctttcgaaga cgatttagca atggttttcg
    23701 ttttgatcaa cgaccagaaa aaagaagtgt ccagcagaaa tgggatgcgt cggacagtcg
    23761 aaacatccag tttttatcaa ggctggttag attccgttga aggggatcta tatcaattga
    23821 aacaagcaat caaaacaaaa gatttccaac ttctcggaga aacgatggaa agaaacggac
    23881 taaaaatgca tggaacgact ttagctgccc agcctccatt cacttactgg tctcctgaca
    23941 gcttaaaagc gatggatgcg gtgcgacaat tgagaaagca aggcattcca tgctacttta
    24001 cgatggatgc tggccctaat gtcaaagttt tagtggaaaa cagccattta tctgaggtac
    24061 aagaaacatt taccaaatta tttagcaaag aacaagtaat tactgcacat gctggtccag
    24121 gaattgcgat tattgaataa agggagattt ttatgattga agtatctgca ccaggcaaac
    24181 tctatattgc cggagaatat gcagttgttg aaacaggcca tccagcagtt atcgctgcag
    24241 tcgatcaatt cgtgacagtc actgtagaat ctgcacgaaa agtcggaagt atccaatctg
    24301 cacaatatag tgggatgcct gtacgttgga caagacgcaa cggagaatta gttttagata
    24361 ttcgggaaaa tccttttcat tatatccttg ctgctattcg cttgactgaa aagtatgcac
    24421 aagaaaaaaa cattctttta tccttttatg atctgaaagt aacaagtgag ttagacagtt
    24481 caaatggccg gaaatatgga ttgggttcta gcggtgccgt gaccgttgca acggtcaaag
    24541 ccttgaatgt tttttacgcg ttgaatttat ctcagttgga gattttcaag attgcagcac
    24601 tagccaattt agcagttcaa gataatggtt cctgcggcga catcgctgct agctgttatg
    24661 gtggctggat cgctttctca accttcgacc atccttggct ccaagaacaa gaaactcagc
    24721 attctatcag tgagttactt gccctggatt ggccaggtct atccattgag ccattgattg
    24781 ctcctgaaga tttacgttta ttgattggtt ggacgggtag ccctgcctct acttctgatt
    24841 tggtcgatca agttcaccgt tcgagagaag ataaaatggt ggcttatcag cttttcttaa
    24901 aaaatagtac agaatgtgtc aacgaaatga tcaaagggtt taaagaaaat aatgtaacgt
    24961 tgatccaaca gatgattcga aaaaaccgac aattactgca tgatttatct gcaatcactg
    25021 gggtcgtcat cgaaacgcct gctttgaaca aattgtgtaa tttagctgaa cagtatgaag
    25081 gagccgcaaa atcttctggt gcaggtgggg gcgattgcgg aatcgtaatt gttgaccaga
    25141 aatctggcat tcttccttta atgagtgcat gggaaaaagc agaaatcact ccactgccgt
    25201 tacatgtcta tagcgatcaa agaaaggaaa accgatgaat cgaaaagacg aacatgtttc
    25261 actagctaaa gcctttcatg ataaacaaaa aaacgaattt gacttcgtac ggatcatcca
    25321 taaccctttg ccgcaaatag cagtttctga tgtcgatcta agtacacagg cagttgggtt
    25381 tacactaagc agcccatttt atatcaatgc gatgactggc ggaagcgaaa aaacaaaaaa
    25441 aatcaaccaa gatcttgcaa tcgtcgcaag agaagcagat ttgatgattg ccactggttc
    25501 agtcagcgct gccttgaaag tcccttcttt agccgatact tatacgatta tgcgacaaga
    25561 atatcctcac gggaaaatca ttgccaacat cggtgcaggg acttctgtcg aaagagccaa
    25621 agaagctatc cgattgtttc acgcagatgc cttacagatt catttgaatg cacctcaaga
    25681 gttggttatg cctgagggag accgtgattt taccaattgg aaagtactta ttcaagaaac
    25741 tcaaacagcc attgacgtcc ccctcatcgt aaaagaagtc ggttttggca tgacaagaga
    25801 aacgctcaat gatctagctg ctttaggagt tcatacagtt gatatcagcg gtcgaagcgg
    25861 aacaagcttc acccagatcg aaaacgcccg tcgctccaag cgggaactga gttatttagc
    25921 tgactggggg caatcgacag tctcttcatt gcttgaagca aatgaagcag acacttctat
    25981 ggaaatccta gcctccggag gtatccgcaa tgcctatgac atatttaaag ccctttgtct
    26041 cggcgcaaat gccgtgggta cttcaggaac cgtactgacg catctgatga atcacggcgt
    26101 agaagaaact attatactga tgaagcaatg gcaagaagag cttcgtctgc tttatactat
    26161 ggtcggcgca acgaataccg cggccctaca ccaacaatct ctgatctttt ccggaccagt
    26221 gaaggattgg tgcgaagcaa gagggatcga cttagtgaag tatggaagac gcacagaaaa
    26281 gagcgtggga caaaagtaaa gaacactttt gtctcacgct ctaaacacgt acaaacggcg
    26341 gaagtaaaag caactccttc ggaaataagc tgaaattcac aaaaatttga aaagcaattt
    26401 tcgtgaattc cttcttattt cttggagtta aatgcttctg tcccagcctc ttttttcgaa
    26461 taaatgatgt ttaatcagct gtccttcggt attcgttcaa tccgctgatt tcacaacctc
    26521 tccactaaac agtgtactaa agctctttta aggttgtttt ccgatatagg caagtatgcc
    26581 tccgtccaca tacaagacat ggccgttaac gaaatcagat gcgctagaag ccaagaagac
    26641 agatggtcca gccaaatcga ttggctcgcc ccagcgtgct gctggcgtac gtccaacgat
    26701 aaattgatcg aatggatgac gttcaccgtt ttcttgtgtt tcgcgtaatg gagcagtttg
    26761 cggtgtagca atataacctg gtccaattcc attacattgg atattgtatt gaccgtattc
    26821 agaagcgatg tttttcgtca gcatttttaa tccgcctttt gccgcagcat aagcactgac
    26881 cgtttcgcgt cctaattcac tcatcatgga gcagatattg atgattttac cgccgccttt
    26941 ttcgatcata tccggaataa ctgcttttga aacgatgaat ggggcattta aatccacgtc
    27001 gattacttgg cggaagtctg ccgcatccat ttcgatcatc ggtgtccgtt tgatgatccc
    27061 tgcattgttg actagaatat caactgaacc tacatcttct ttgatctgtt gaaccatcgc
    27121 ttgaaccgct tcttcatcgg tcacatcgca gacataacct tttgcatcga tgcctgcttc
    27181 tttataatgc gctatacctt catcaactga ttcttgattc aagttattaa atacgatttt
    27241 tgctcctgct gtagctaaag agcgtgcaat ctcaaatcca ataccataga cagcaccggt
    27301 gactaatgct acttttccat ctaaacgaaa catatccata ctaaattcca tcattttctc
    27361 tcccttatgc ttattttaat tgatccattt gcaccatatc catgtctgta taggtgatat
    27421 tttctccgca cattgcccag atgaatgagt aattgcttgt acctacacct gaatggatcg
    27481 accagcttgg cgaaataatg gcttgttcat tgtctacaac taaatgtttt gtttcatctg
    27541 gtttgcccat catgtggaac acacgtgtat cttcattggc ataatcaaag tagacataag
    27601 cttccatacg acgttcatgt gtatgacaag gcatcgtatt ccaagcgctt cctggttcta
    27661 aaatcgtata acccatttgt aattgacagc tttcgcatac atttggatgg atgtattggt
    27721 agattttacg ttcattcagt gtcaggcctt caccagtctc cattggtttt acttggtcga
    27781 tactgatttt tacatttgga tatttatgat gagctggaac agaactaata tagaatttag
    27841 ctgggttttc agcatcttga gaagaaaata caacatgtcg tgtttctttt ccgatatagt
    27901 atccgtcttg ttttttcatt tcttcttttt gcccatcgat ctcgatgaat cctggtccac
    27961 cgatattgat cacacctagt tcacgacgct ctaagaagta atcaacacct agttctttgt
    28021 ctaatgtgat ttctaattct ttttcagtag gtgtcactcc accaaagatc attcgatcgt
    28081 tgtgcgtata agtcaaactg attttccctg gttcaaatac cttttctact aaaaattctt
    28141 ttctcaattg ttccgttgaa taatgacgga tatcttctgg actgtgtgta taacgtgttt
    28201 ccatttcttg cattttcttc tactccttct atcgaatgat ttttccagag ccgcatgcta
    28261 aaaattgtgc gacttcttct tgactaaatt ggttgcagtc cccatggatc gtatgcttca
    28321 aggcagaagc tgccgtagca aaatcaatga tttcttgcgg agacatattg gataaaatcc
    28381 catggagcac gccacctgca aaagcatctc cgccacctac tcgatccacg attggggtga
    28441 ttctatggac ttgggattcc acatattcat ggttcatcca caatgtcccc ttcaattcat
    28501 tttcacttgc tgaatgaacg gtacgcttgg tcgaataaaa cacctgaata ttcgggaact
    28561 tttcctgcat tttttgataa taataaatta gaggttgttc ttctgcttct ggcgctttct
    28621 cgatacctaa caaataaaga gcatccattt ttccagctga gcagatatct actaaaggta
    28681 aaagctgatg gattacttcg ctggcttctt gctgtgtcca taattttcca cgatagttga
    28741 tatcgaagct gatcaggcag ccagcttttt ttgcagcttc tatcacctgt ttcgtcattt
    28801 tttgccattt tttagacaaa gctggggtga ttcctgaaac atgaaatata tctattcctt
    28861 ggaataactc ctctagcgac cattccaaat gatccatttc agcaaaactt gatccggcac
    28921 gatcatagat cactgaggcg gcgcgttcgc cactaccagt ttccatataa taagtaccta
    28981 gtcttgatcc accagataat acctgtttcg tatctactcc ataacattgc aagtgctttt
    29041 tgactgcttt tcccaatgcg ttatcaggta cttttgtagc aaaaatcgct tcatgtccgt
    29101 aattagctaa agaaattgct acgtttgctt cccctccgcc ataatgggca gcgaatcgtt
    29161 cacttgaatc gatacgggtt ccctgctctg tggacaatcg caacatgatt tctccgagtg
    29221 tcactacttt tcccataagc agctacctct tgatttcttt catttttgct gcatactgtt
    29281 gcgcgacttc cgttactttg tcaaaatctc ctgtagctgc gggtgctaaa aggttcccac
    29341 ctactccgac tgttacgaca ccagcatcga accactcttt catattgtcc agactcacac
    29401 cgccagttgg catgatattg acttgaggca tcggcgcctt gaaggcagaa atgatacttg
    29461 gtccataagc gcttccagga aatagtttga cgatatctac cccgcttttc agcgctgttt
    29521 tgatctcggt aatagtcata catcctggta agtaaggaat ttgatacaga ttgcacatct
    29581 ctgccgtttc ttgatcaaag gaagggctaa caatatactc tgcgccagct aagatagcca
    29641 agcgagctgt gacagcgtct aatactgtgc ctgcgccaat cactatttct ggttggtctt
    29701 tgtagaatga caaaagttct ttgattactt gatctgcttg agggactgta aaagtcaact
    29761 caataccagt tagaccacct ttgatgattg cgtggcaagc attcaaagct tcttctttgc
    29821 tttttccgcg taccaccgca atcactccgg cgtttttcaa tcgagataaa atatcaattt
    29881 ttttcatctt ctccacctat ttcctattta gaaattttat tttataactt ggaaatctat
    29941 acccatatta tacggcagaa aagaaaaatt gcaaacgctt ttttcattat ttttgaattc
    30001 tttgctcgat ttcgcttttt gtttgcttga gggcactgat tatttgttct tttgtctcat
    30061 ctgttaaacg atatttcggc atacttacac taaatgcacc aatgatttgt tcgtttttca
    30121 cgattgaggc tcctatacaa aaaatatcac gttcgatttc ttcatcgtca aatgcgatgt
    30181 gggtttcttt taccgttttg atttcctttt tcaaccgtaa tgcattggtg atcgtatatt
    30241 ctgtgtaagg gatcaacgga tgcttttcaa gataatcagt gtactgctct tcactgaatt
    30301 ctgctaatac ggctttgccc atcgcagaat tgtataatgg tcgggtgatt ccgatttttg
    30361 aagacatgcg gatcgtttga tgttttggat ctagtttgtt cacgtacaag atctcattgt
    30421 tgtccaatac ccctaagtgg atagtctcat cgatcttttg ctgcagctgt tctaaaaacg
    30481 gtaaagtcaa ctctaccaaa tcgatttgtt caatgttttt attcgcgtag cgaataagct
    30541 ttgcacctaa acgatagttt ttctctgaat ttttatttac gtagccgatc atcaacaaag
    30601 tatctagtat tttcaagact gtagaagagg tcattcccac accctttgcg atcgtctgca
    30661 aagagacatc ttggttttcc gctaaatagt ctagtatttt agaggctttg atcaatacag
    30721 ttccataagg ctttttattt tccatataat attctcctat ttctttataa gaaaaattat
    30781 agcggaaata ccatcaattt aaaagagata tccagatata aactaccatt tctctttaca
    30841 ggcaatttaa tgttgaagat ccgcttcgtt tttacatcaa actttgatat aaagcaatga
    30901 tttcttctac tgtcgtttct cttggatttc ctggtgtgca tacatctcgc aaagcatctt
    30961 ctgcaattgc tggaatatct gcttctttta cacctaattc agaaatggtt tctgggattc
    31021 caaccgcttt gctcaaccga tcgatctcac cacaagccgc ttctcttaca tcttctaaag
    31081 acatttcagc tgctccttta atccctagaa caagagcgat ctcacggtac ttttctccag
    31141 tatattcttt gttatatttc atgacagttg gcaaaagtgc tgcacacgct acgccatgag
    31201 gaatgttgta ccatgcactt aacgggtgag ccatcccgtg taccagtcct aaaccgacat
    31261 ttgagaagcc cattcccgca atatactgtc ctaatgccat tttttctcgc ccattttgat
    31321 cgccatctac agaagcttcc aaagaatggc cgatgatttc gattgctttt aaatgcagca
    31381 tatcagtcat ttcccaagcg ccttttgtga taaacccttc aatagcatgc gtcatagcat
    31441 ccatacctgt tgatgcagcc aattttttcg gcattcccat catcatatcg ctgtcgatga
    31501 acgcgacgat tgggatatca tgaggatcaa cacaaacaaa ttttcggtga tttacttcat
    31561 ctgtgatgac gtagttgatc gttacttctg ctgctgttcc agaagtcgtt ggtatagcta
    31621 atataggtaa acatggattt ttcgtatcag caacaccttc taaactaatg acgtctgaaa
    31681 actctggatt cgtcaaaata atcccaatgg cttttgccgt atcgattggc gaacctccac
    31741 cgattgcgat caaacagtct gcctctgcct ctttaacaaa agccactcca tcttttacat
    31801 tttggatcgt tggattaggt acgatcccgt cgtataaagc ataagcgatt gctgctttat
    31861 ctagaagttc tgttactttt gttgctatac cgtgctcgat caatcctttg tcagtaatga
    31921 cagctgcttt gccgaatcct cgctgctgaa attcagggac gatcgactca atcgctcctt
    31981 ttccaaaata cgatgtttca tttaaaatca ttcgattact cattttctat tcctcctaat
    32041 ttgtattatt tttcacaata aaaacgaaag aaccccaagc aaccggttgc ccagttgctt
    32101 gttgctacag ttcaaagact ggcatcaatt cccaactgac tggagaggca tctggatttg
    32161 tctccatgat atcttccatg tacttccacc atttttgatt gatagatgta tttgccattt
    32221 tttcccataa cttttcatct tcgatcacta agtaaccaaa taacaaactt gtactcggat
    32281 caagatagat cgaatagtcg atgaccccgt gttcacgaag tgctgtacgc atttctggcc
    32341 aaagttcatc atgtcttttt ttgtattctt cttgtttttc tgggtaaact ttcatgcaaa
    32401 aagctttttt caccatgtca gacacctgct ttcgtatgaa cttcctccaa ataacctgct
    32461 tttggagtga caccaaacgc atctgctaaa tgccacaggt tttcgtccgt gattgtttgc
    32521 aagattggtc cttgcgcttt gacgtacgta tagacttctg ctgccttttc tgctgtctcg
    32581 atcaaaccaa agacttcatc catgtctttt cctgacccgt agattccatg ttgtggccat
    32641 aaaaccaatc gagtttcttt cattttttca gctgttgctt ccccaatctc atttgttccc
    32701 ggaaccatcc acggaatgat ggaaattcct tctggaaaaa caactaagca ttccgtacac
    32761 atttgccata gcgtacgact aaaggaacgt tcgtctaatt catgcgtaaa actcatcgct
    32821 aatagatgac tagcatggca atgcataacg atccgattat ctgggtctac ttctaaacgg
    32881 gcgatatgac tcatgaaatg acttggcaac tcgcttgtag gaaggcattc gttttccagc
    32941 ccccacaaaa gttccagtgt tttgccatct tcagcaactc gaacgattcc aagattctcg
    33001 gcaggttcgc tcgctacatt tttaaaatat cttcctgaac cagttacaat aaaatagcat
    33061 cctgctaaac ggctggcatc aaaaatcatc gagatgcggc ggatcacttt ttcaggatcc
    33121 aagaacggtg tgatctcttc ttcttttagt aaataagaaa tattcccgcc atttctttca
    33181 tcccatccca agcgataaag attcgacgtc gtttcgatca tttctttcac ataaggcgct
    33241 tgtaaaatat ctattttttt caatatagcc acactcctat tttcttaatt ccaacacgtc
    33301 tttttgatat tcctggactt cttccagcca atccaaacca actggaactt gatttttgta
    33361 acagaaataa ttccatacat cggcatacgg gaaatctttc aattcttccg tataagccat
    33421 tcttgaagta aagtcaaaag ccagctccat ttctttcaat cgctcaactg gttccagcat
    33481 agctttcagc agtgcttttt gtgtatttct cgtaccgatg acccaagcag cgatacggtt
    33541 gatcgttgca tcaaagaaat ccagaccgat atttgttttt tccaacaatt cgttacggac
    33601 taattcttta gcgatttcct gcaattcatc atccatcaaa accacatggt ctgaatccca
    33661 acgcactgga cgggaaacat gcaacatgat tcctttgctg aataaagcta atgaagataa
    33721 tttattggaa atcacttctg ttggatgaaa atgtccagca tctagacaaa caagtttgtc
    33781 acgagtcaac ccgtaaccca tataaaattc atgggaaccg actgtataag cttcagcgcc
    33841 taaaccaaat agtttgcttt ctactgcatc ttgtacatac cgttcatcta actcttctgt
    33901 aaaaatttca tcgagtgatt ccattaaacg ttcccgtggg gtaaaacgat caatcggatt
    33961 atctttcatc ccatcaggta cccaaaagtt attgatactt gtttgcccag tttctttccc
    34021 aaagtactcc gcgattttgc ggcttctttt cccgtgttcg atccagtatt cacgaacttc
    34081 tttatctgga tgagccaatg taaagccgtc tttcatcatt ggatgcgaaa agaaagtcgg
    34141 attgaagtca agaccgattt cttctttttt tgcccactct acccattttt caaaatgttt
    34201 cggctcaatt tcatttagat cgacagattc ttctgtatcc aaatagatag catgaaggtt
    34261 caatttgtgt ttgcccggta tcaacgaata agccttctcc agatcttgtc taagctcttc
    34321 aggtgttcgt gcggctcctg gaaaattccc tgtcgccatg attccaccgg tcaattcgcc
    34381 atccggtgtc aagaaacctt tgacatcatc tccttgccag caatgcatag aaattttgat
    34441 gtcctgtatc ttttctagta cagcatctgt atctacaccg atagttgcat atttttcttt
    34501 tgcttgttcg taatttcttt caatcgtgtt catacgatta ctcctttgat tttattcacg
    34561 taccattcca tcgtgttttg cttattttca tctgggtaaa aagtttcaca tggaaacgac
    34621 tgtttgatta catttcttgc ttgttctata ttcgaaaact gacctgtact gagcatttgc
    34681 atggcaacat tcccgattgc tgtggcttca ctaggtcctg cttctacaat gattccggca
    34741 taatctgctg tcaattgatt cagtagacga ttattcgatc cgccccctac gatgtgcagc
    34801 ttttccaatt tcgttccagt taagtgttct actttgatca gctcttgtgc gtaacaaaga
    34861 gcaagattat catacacaca acgagcgata gctcccgatg agacagggac tggctgctct
    34921 gtttcaaaac agtattgctg aatctcttct atcatatttg ggggattcaa aaatcgaggg
    34981 tcattgattt ccatcacttg ctgcagcggt ttttcttttg cagcaagctc tgccaattcc
    35041 gcataactgt actcgtactc ttgcattcgg gcaacttcct ggatcaacca catccccatg
    35101 atgtttttca aaaaacgcac cgtgttatgg gcaccccatt cattcgtata attttcagaa
    35161 aaagcattgc gagaaacatt ggcgatcttt gtttcaatcc ctaaaagcga ccatgtccca
    35221 ctgctgatat aaccccaacg ttctccttga cctggcgttc ctaatacagc tgacgccgta
    35281 tcatgacttg ctactgtgat aaaggtcaca tctggcaaat catattttga aaattgttct
    35341 ttttgcagat ctcctagtat cgttcccggc tctgtcaatg gtggaaataa ttccttcgag
    35401 acaccgattt tttcaagaag ttctatttcc cattcttttg tccctgcatt cagcagctgc
    35461 atagtagatg cattagtttt ctccgtcacc atgttaccag taaagacata ccctaaataa
    35521 tcaggtatca gtaacaattt atgtgctttt gccaaatttt ctttttcttc agcaaacaat
    35581 tggaacaagg tattgaaagg ctggatctga atccctgtct gctcatacaa cttatctaga
    35641 gaatagattt cagaaaactg ttctactgct ccattggtac gcttgtcccg ataagcaatc
    35701 ggatcattta tccgatcccc ttgttcatca atcagacagt aatcgactgc ccatgtatcg
    35761 atccccgcaa aaaggcgatc aatccctgtc tgctttaatt tttcaaatcc aatcaaaatc
    35821 tctttgataa gataatcgat cttccagcga tcgtgaccgt ctttgttccg aaagccgttt
    35881 ttgaaccggt gtacttcttc caagatcaaa gaaccttttg catccctcgt acttttcatt
    35941 agtcgtccgc ttgatgcacc gatatcgatg gcaacaaatg ttggattcat ttctccacct
    36001 cttttacttt attgttgatt agcactttat taataaagcg ttatcattta ttgacaatgc
    36061 tatcataata cagaatctta tattttgctt cacactattt tggtatataa ttgcattatc
    36121 ttgacaagtt gggagtgttt acatggatta ctgggaaaaa gccaaccact catggtcgga
    36181 agactcaaaa agagtgatct tgacgcctac acaaagaagc aggaatttat ttttttatat
    36241 ccaagaaatc ggttacttca aagcaccaat cccttactat actgaacgag cacatttacc
    36301 ttcttacttg ataaagttta ctttgtctgg caaaggttcg cttacatata atgataatca
    36361 gcaacagcta aaagctggag acttattttt tattgactgc caagaatatc agcgttatca
    36421 aacgatcagc gaagaaccat gggaaatgga ttggatccat ttgaatggtc agaacgtcca
    36481 atcattttat caggagttca caaaagacgg ccataacacc ttccattcaa caggagatcc
    36541 atcagaaaac aagatccacc atttgatcac agaattgatc cacatgcaac aaggcacgaa
    36601 tgcccgtacc gatttccagt cctctgtagc tatccacgag ttgctgaatg aactgatttt
    36661 gcaaaagtat cagctagatt tcgaagaaga ggatattccc gcctacgttt acaaactgaa
    36721 gcaatactta gacgaacatt tcaaagaaac gattacactt gatcaattag aacaacaatt
    36781 cttattgaat aaatatcagc tgagcaaaga tttttccaaa tttatcggtt ctccaccaat
    36841 cgattatttg atcagcaaaa aactttctta cgctaaagac cttcttcggt atacagaatt
    36901 tacggttcga atgatttccg aagaaatagg gattgagaat tttgcttact ttagccgcct
    36961 gttcaaagca aaaacaggac tatcgccgag agactttcgt aaattcagct gattcatata
    37021 atatgtacgt cattttttca aaatattttg aaatatatag ataaaaataa aataaccgca
    37081 gtttctgctt ctatgtaaac aacagcagct actgcggtta ttttttagtg atcattctca
    37141 ttgttcatct tcaaaatgtt cataatgaac caactgtttc tgtgtatcac gtttcaaaaa
    37201 ttctttaggc gttatgccga actctctctt gaatgctttc agaaaatgcg gataagaaga
    37261 aaaaccactt ttactatata cagcactaga gctgcggtat tctcgcaaca agtgcttggc
    37321 atagatcagc tttttcttca ttacatactg atgaaacgta aatccagtgt actttttaaa
    37381 ttctcgtgtg atatggtatt tgctgacaaa aaactgcttt tccatttcct ctaaagaaag
    37441 cggatgagat aaattttttg agatatattg taacatttgt tccacacgct cattaggaac
    37501 tacagcattc tgttcttgcg cactctcttc tttttgtaca acttgattga gaaaaatcaa
    37561 gtattctacc agagcttgtt catattttat gtcttcaccg taaatttttt tatcaggagg
    37621 atggtcgata aatgataatt tttgcttcaa tacttcctgt tctatttgca atacacgact
    37681 cctcttctct cccattggtt gaaaacaagc cgatagatta gaccatggcg tggaacgact
    37741 ttctagaaaa gaaggggtga caaagatata gacacgctcg aatacatctg aagattggcg
    37801 gacgatacga tgcaaatcat tggaatggat gagcagcaca cttcctgctt tgatcgtaaa
    37861 ttgtcgtccg ttcaaataaa aagtcgcttc tccctttaat gtagcatgga tctcatagaa
    37921 atcatgatga tgatagatcg ttttattttg gctgacgaca tctttgacat gatagatttc
    37981 atactgatca gaaaccatcg tattgacttg ttcaccgctg attttctttt ggagcatgtg
    38041 ccgcacctcc ttttgttcac ttatgcacaa ttttattata ccacgttttt tgtaatcaaa
    38101 aagagctgct tttatatact cttataaaaa agaagagacg tggcatcttc tagccccgcc
    38161 ccctccattc taaatattag ttaaccaacg tcttctttac attattcaag aagacttctt
    38221 ccataacgaa tcccatcatc ttttgtttct tcaagaacca catacaggta cggacgattc
    38281 ttcatgatga tttctttgat ttttgtgtac tcgatcacac cgtctcccaa atttaccggc
    38341 acgatttttt cctgttcgac acgaaaatct ttcaaatgaa ccgcacatat cttttcacca
    38401 aaacgttcaa aagcttcttc taccaattgg acttgttctt gataatcact acttgtgatc
    38461 aaattggtcg gatctaaaat gattcctaga tagtccgaat ctactgcttg gatcagctgc
    38521 tctacccttg ctaaagaata caccggatga ttcaaacctg gttctatccc caccatcatt
    38581 tggtattttt ctccagcttt taccaagcga cggataacgg acacagcttc agcaaatgct
    38641 tcatctgtga aattttcttc cgtatattgg atttccggca aaacacatcc agtttccgaa
    38701 gcaaccatcg acgcaccaaa ggaagaagca tagcgaagat actgctcgaa ctttgtcagc
    38761 aactcttgtc gtatcgttaa atctggatga atcatattga tatagcaact taaaattcct
    38821 acggtcactt cttgcttttc taaaactcgt ttgacataat ttcccatccc agaattgatc
    38881 tcatttgcgc cagaaggtat ttcaggaaac gaaagaccta aggcgagctg cagtgtatga
    38941 atcccttgtt cttttgtttt ttctgcaaga tcttctatcg tttggacttc ggaaagatca
    39001 tgtcctctaa ttgtaatgtt caacataact attctcctaa ctcagcatat tgggtagcca
    39061 catgacgatt tgcgggaagt aagtaatcaa aaacaagacg actaagataa ccccataaaa
    39121 aggaagaagc ggtttcagca ttgcctctgc ttttacgcct cctacacttg caccgacata
    39181 tagtcctgta cctactggcg gcgtgatgga gcctacacac agattcatga ttgaaaacaa
    39241 cccgtaatgt acaggatcaa cccctacact tgtgacgatt ggtaaaaata ttggtgtaaa
    39301 aatcaagata gcaggcgcca catccataaa catacccacc agtaataaca caagattgac
    39361 taataacaga ataataaatt tattatccgt tacgcccata atcaacgaac taattgcctg
    39421 aggaataccg gtaaacgcca tggcgaaaga catcatggaa gaagtagcca ataagaacat
    39481 gatcgtccct gacattgcta ctgattgaaa caacatatta ggtatatctt ttagttttac
    39541 cgttttatag taaaacatag caatcaacag ggagtaaatg acagctatcg ctgaagcttc
    39601 tactgctgta aatatccccg tcaagatacc accgataatg atgacaatca atagaaggct
    39661 aggaatcgcc tcttttatta tttttccagc atgagccatc tgtccttttt cgacaacagg
    39721 gtatttattc tttttagcaa cgatgaatgc tactagcatg attcctagcg cccacaaagc
    39781 gcctacgaga taacctccca taaacaaagc agagatcgaa gcaccaccag caacaagtga
    39841 atacatgata aaagcagtac ttggaggaat gaccatacct gtcggagctg acgcgatatt
    39901 gaccgctgtc gcaaacttcc ggtcatatcc ttcttccact tgctgaggga tcaacactcc
    39961 gccaatcgcg gtagaagcgg caatggccga gctagagatg gaaccaaata aagcattccc
    40021 taacacattc gtatgagcca aagcccccgg cacgcgcccg acgaacaaca tcgcaaaatc
    40081 cactagtttc ttagctatcc ctccattatt catgataatg cccgagagaa cgaaaaacgg
    40141 aatagcgatc agcgaaaaac tattgatact tcccaccatt ttttgagctg aactaaaagc
    40201 agaaacatca aacggtataa ctaacaataa agtcatcatc gatgagaatg caatacttat
    40261 agcaatcggc atccctaata caagcaacac aacaaataca aaaaataaca ctaatccggc
    40321 ttctattgcc attttattcc tccattttta tattttttct tgaattgctg gcttgttgct
    40381 taatgtatcg attagattga tcaggctata gataatgatg agtacccccg atacaggtac
    40441 tgacagataa acatatccca taggaatact taaagaaggc gagatctgcc ccattgtcaa
    40501 tgtgacagca ttccatccgc catacaccat gatcatcgca gcaaatacca gaaataaact
    40561 ttgaacaaca acttctaaaa ttttactttt tttgccagtt aatttttcac ttaaaaccgt
    40621 tacggctaaa tgtgcttttt gtcccacaac atacgcggaa gacaacatgg caaaccagac
    40681 aagaccgaat cgaacaagct cttccgtgac cgtatttgga tttcctaaaa ccgttctgga
    40741 aaatacttgc cataaaacaa cagcgaccat cccaacaagc aaaacagctc ccaggatctc
    40801 taataccttg tttaaaatca ttttcatcac agctacgctc cttgctcttg gatcttttga
    40861 taaaggtctt tgtaggtagg atcgtttttg aatatatcat gaagtggggc aactgcctct
    40921 cgaaacggtg tattatctac atcattgaat tggactccat gttcttcttg tgctaaagct
    40981 ttttcttctt caattgcttt tgcaaaagct tcaatttcaa aaaccgttga ttctttcgct
    41041 gcttcttcaa tggctttttc ctgctcatca gttagctgtt ctttgatggc atcattcatg
    41101 atgatgatat ctggcacacg tgtatgctca tcataggaat agtatttagc cacaccacca
    41161 tgtccagctg tatacaagac aaattcattg ttttctgatc cgttgatcaa attggattga
    41221 agagacgtgt acacttcatc acttcccata ggtacgggcg aaccgcctaa aagctctacc
    41281 attttgatag cggtttcgct ttgcatcaca cggatcttct ttcccttcaa atcttccggc
    41341 gtatggatcg gaccgtctac catataaaag ctgcgctgac cagaatcata ataggtcaat
    41401 ccggtaaatc ctaaattttt ggtcgattgg tagattggct ccattatttc ttcattatcc
    41461 atcaccttaa agaaatgttc ttcatcattg aatagataag gaactgaaaa aatcgaataa
    41521 tctttagaga aactttccaa cgctgaggca cttacttttg tgaaatctac tgctcctgac
    41581 tgtgtcaatt cgatcagttc acgttctcca cccagttgtc catctgggaa atactggatc
    41641 tgtacggaac catctgtttt ttcttttact aaacgcccaa attcattcat tgcatcaatt
    41701 actggctggc tgttgcttgc ataagcaaag cgcaaggtaa ctatctcatt tacatctgca
    41761 tctgcgacag ttgccacact agaattattt ccgcagccgc ttagacctag cagacctagg
    41821 ctaagcgaac ttgctgcaaa cagcagtgat gtttttttca tatgggtttc ctttctttta
    41881 acaataagag acgagcaatt ctgtcaaaca aagcaccgtt aacgactgtc cataaggcat
    41941 tgctgtgatt ccgatattcc gataaaaatc taaactgtcc cccattcctg tcccgattga
    42001 aacgttttga acttctcctt tttcatcgat ttgttcaagc aatccttgga tagcacgata
    42061 agcgacttct ttatattctt gtggtaaata acgtttatgg accgctttca aaataccgta
    42121 agcaaatcct gcagttgcag aagattctac gtaagaagaa ggatcatcca acaacgtatg
    42181 ccataaaccg ctttcagact gataagtttt taatgcacgc acttgtgctt caagtgtttc
    42241 gatcaataat ttgcgcaatg catcttcttt cgataattct aagatttcaa tgatctctgg
    42301 aatagcaatc gtcaaccagc agtttccacg agcccaaaat gcttcggcat agttatgatt
    42361 tccttcaaac gtccagccgt gataccacaa tcctgttcgt ttatccatca agtatttgat
    42421 atggatcata aactggtaac gagcttcttc taaatattct gggcgattca acagtttccc
    42481 gatttttgcc aaaggaagca ctgtcatcat caatgtatcg tcccacaact gattcttatt
    42541 ttccggtcca tatgtggcat gctgtaaccc gtcttcattt gtccgaggca tgtcattcat
    42601 gacccattct gcccattgtt ctaaataagg caaatagcgt gaatctttcg tgtcttcata
    42661 caagtaagcc atagtcaata gcggtgccat tgtattgacg tttttgggcg gagcgccttc
    42721 ttccatacga tcctcaaacc attcattgac cacttgataa gcgcgaggat tttttgtcat
    42781 ctggtaattt ttataaatac catatagacc gacaccttgt ggccaattcc acactgtcca
    42841 gcttttgtca tctactttca gtccatcaaa gtccaacaaa aattcaccat tatcgtcttt
    42901 gatcgttgtc aggttttcaa cgagcaggtc aattttttct ttcactaatt ctttaggtac
    42961 aaaaatctct tctttaataa tcatctttac gccacctttt taaacgcttt cattttatat
    43021 ccttaatata gcagtaatac cgtccactat aaatatcgct ttttgaacaa aaactgtcta
    43081 aaattgacct aaatgttaaa taacaaaagt aactttcagt tacttggaaa ttaaaaaaag
    43141 aacttggaga aacaacgttt tccaagttct ttttcatcta ttttcttatc ttttttctac
    43201 gctttctttt gcttatccgt tgtaagcatc aatgatgatc tgtttcaatt cagagatcaa
    43261 tggttctttc ggattagctg tcgtacattg gtcttcgtaa gctaattcag ccatacggtc
    43321 tacggttgta tctagtgttt cttgtgtgac tccttgagct tttagactca tgttgatgcc
    43381 gacagatttt cctaattcat aaacagccgt tgctaaagct tcgactaatt cctctgttgt
    43441 ttcgcctttc agacctaaga attttgcgat atctgcgtaa tctgtatctg cacggaaata
    43501 gtcatattta gggaacatcg catgtttttg tggatctttt gcattatagc ggataatatg
    43561 cggtaaaaga atcgcatttg tccgtccatg agggatcccg tattccccgc cgattttatg
    43621 tgcgactgag tgacaaatac ctaggaatgc gttagcaaac gccataccag ccattgtaga
    43681 agcgttgtgc attttttcac gtgattccat atcaggtgtt tttactgatt tttctaaata
    43741 gtcaaagact aacttgattg cttgtaggct caatccacgt gtataatctg aagccatgac
    43801 tgaaacatag gattcgattg catgtgttaa cacatccatc ccggtatctg ctgtgacaga
    43861 tgctggaact gacatgacga attgaggatc gacgattgcg acatctggcg tcaatgcata
    43921 atctgctaac ggatatttca catgtgtttc actgtcagtg atgaccgcaa atggcgttac
    43981 ttcagaacca gtccctgatg ttgtcgggat acatacgaat tgtgtttttt ctggtttgtc
    44041 gatcttatat gtccgtttac ggatatccaa gaatttttgt tttgcaccaa agaaagatgt
    44101 gtctgggtgt tcatagaaca tccacattcc cttagctgcg tccattgcag aaccgcctcc
    44161 aagagcgatt actgtatctg gcttgaagtc tgccatcagt ttcgttcctg cgtatacggt
    44221 atttgtcgat gggttcggtt caacatctga gaagacttcg atcttcacat catttttacg
    44281 tcgtgccaat acttcacgaa ctgtatcgca gtaaccgaat tggaccatac cagggtcaca
    44341 aacgatcatg acacgttcaa cgttttccat tttctctaag tacaatagag agttcttttc
    44401 aaagaagatt tttggcggta atttgaacca ttgcatgtta tttctccgtt tcgctacagt
    44461 tttgacattg attaagttta cagcagagac gttacgagaa acagagttct taccataaga
    44521 accgcatccc aaagtcaatg acggaatcat ttcgttatag atatcaccga tgccgccttc
    44581 tgcagatggt gtattcacta aaatacgaca agctttcatt cgaagaccga atttgacatg
    44641 caactcttcg ttttctgaat ggataactgc tgtatgtcct aatcctccaa gattcaacat
    44701 accttcacac aaatcaaacg catggtccgt gttgttagct ttgatcatgg caagaactgg
    44761 agaaagtttt tctcttgata gcggataatc tgggcctacg ccttccaatt cagcaatcag
    44821 cattttcgtt ccttttggta cactgattcc tgccaatttt gcgatttcca tcgcagaatg
    44881 tccaacgatt gatggattga ccgcatattt tccttcgttc atcactgcat cttctaattt
    44941 ttgcaattca tctggtttta cgatataaac ttggtgtgct tggaattctg cttttactgc
    45001 tgcatagatt tctttatcca cgatcacagc ttgttcagaa gcacaaatca ttccattatc
    45061 aaatgttttc gaaacgatca aatcgttcac tgcacgttta atttttgctg ttttttcaat
    45121 ataagctggt acgttacctg gacctacacc taaagctggt tttcctgtag agtaagcaga
    45181 cttgaccatt ccagctccac ctgtcgctaa gacgatcgcg atacctggat ggttcattag
    45241 catagaagtc gcttcgatcg aaggatgttc gatccattgg atacaatttt caggagctcc
    45301 ggcagcgata gcagcatcac gtaccactcg tgctgcttct gcagaagatt tttgggcact
    45361 tggatggaaa gcaaaaacga ttggatttct tgttttcaac gcgatcattg atttgaaaat
    45421 cgttgtggaa gtcggattcg ttgttggagt tactccgcaa accacaccga ctggttcagc
    45481 aatttcaatc aacccttttt ggacatcttc attgatcaca ccaactgttt tatcatgttt
    45541 gatattatgc caaatatatt cggacgcata catatttttg attgctttat cttcgtaaac
    45601 accgcggcct gtttcctcta cagccatctt cgctaatggc atatgttgat ccaaagctgc
    45661 cattgccatt tcatgcacga tatggtctac tttttcttga tcaaagcttt ccatttcttt
    45721 caatgctgca tttgcttttt ctgccaaatc atcaatcatt gcttgtacgt caattgtctt
    45781 cgttttttct ttttctatta ctttagccat cattatcctc ctaatgggtc atggttattt
    45841 gttaaataat tcacatgtat atcatacaat atttattttt ctatgtaaac acttttttgt
    45901 gatttttttc acagttattt ttaaatataa aattgcttta tttacaggtg tttgtataga
    45961 aaaatatata aagttattta ttattattta tatgacacac ccgattattc aatattgagc
    46021 aatatatccc atgctcttat ctctttcttt tttgaataaa aaatgaggta ggacatcttt
    46081 ctgccctacc tcgtctttaa ataagctttg atacttattt ttcttccttc tcttctgtct
    46141 cttccagcgt ttctgttgtt tcagttttta cttcaactgt ctcagctggt tcttctgttg
    46201 tttcaacagt agtcgttgca tcatttgtta cgacagtccc tggtttgacc gttttgattg
    46261 ctgcacgatc gtactcaagg aagatccctt cgcagtctaa aacaactgtc cgtttgtcat
    46321 tgtcgatttc tgaaacaact ccatgtaatc cgccgatcgt tacgactgaa tcacctggtt
    46381 tcatgctatc taacaagttt tgacgttctt gctgttgttt cttttgcgaa cgtgacataa
    46441 aaaaccacat tgctaatagc gcgataaaca tcacaagcat tggtaatgtt cccatttttt
    46501 tcacctcact aattctgtat ctacaaaaaa cactttagca gaaaaatgct gataacacta
    46561 gttttttact taatttttaa aagattttcc tttagaagct ttttgcgttt tctttattga
    46621 acccgtattc ttcaaaaaag gcttctctaa attcaagcaa attatcatcc atgattgctt
    46681 gacgtacttg tttcattaga ttcaacaaga agtataaatt gtggtaagaa gtcaaacgaa
    46741 tcccaaatgt ttcatcacat ttgatcaaat ggcggatata ggcacgtgta tagtttttac
    46801 atgtataaca atcacatttc tcatcaattg gacggaaatc atgggcatat ttcgcatttt
    46861 tcactactag acggccttga gaagtcatac atgtgccatt tcgagcgatt cgagtaggca
    46921 agacacagtc aaacatgtct actccacgga taacaccatc gatcaatgaa tcagcagcac
    46981 cgacacccat caagtaacgt ggtttgtttt cggggatcaa cggtgtagtg aattctaata
    47041 cacgattcat ttctgattta ggttccccga cagataaccc gccgattgag taaccaggga
    47101 aatccatccc gactagatct ttcgcgcttt gacgacgaag atcttcaaac cctgctcctt
    47161 ggatgattcc aaataatcct tgacggtctg gattagcatg agctttcaat cctcgttctg
    47221 cccatcgaga cgtacgttct actgattttt tcacgtagtc gtaactttca tcgaatggtg
    47281 gacattcgtc aaaactcatc atgatatcag agcccaattt attttggatg ttgattgctt
    47341 tttctggtga taaaaacata cgcgaaccgt tcaagtgatt tttgaaatgc acgccttctt
    47401 cttcgatatt ccgcatatca cttaatgaaa aaacttgaaa gccgcctgaa tctgttaaaa
    47461 tcggttgatc ccagttcata aatttatgca gtccgccagc ttcttctact aagtcttcac
    47521 cagggcgtag ccataaatga tatgtattac ttaaaataac gccagcaccc atttctttca
    47581 actcttctgg ggacattgtt tttactgtag ctaatgttcc tactggcatg aacattggtg
    47641 tggggaaagt tccgtgtggc gtgatcaatt cccctaaacg cgcgccagta tgtttttctt
    47701 tcttgattaa acgatagcga atggcaggtt gcgtcattca tttccctact ttctatataa
    47761 aatatcttga caactcccac catcataatc gtttcaagtg ctttttgcaa gttccctcgg
    47821 cttccttcta ctttatttaa tattcttttt tttatccttt ttttatgaat aacaaaaaaa
    47881 agaaaaacat tatgacagaa atattttttg atacatggta tattggtgtt attaaagaaa
    47941 aggagggaaa aatcatgcaa tcttctgcag aattaaaacg ccaagcaaaa gagagtctaa
    48001 aaggacgttg gggacaagct gttttactaa atctaatccc tacattgatt ggtattgcta
    48061 ctattcttct tattatgatt cctattatct tgtttgccac caccatatat gatggatcag
    48121 cgagcgtctc agaagcgaca acttcaggag gcggtagttc aggaggcggt ggcggaatta
    48181 tttccagcat cattagcgct ttgttcatga gcggtatttc ttggacttat cttgatattt
    48241 tacgtggaca aaaagatcag atcgaaccat tcaaagatgc atttcgtgga ttcaaaggtt
    48301 tgtttatcgg cggagtgatc agcttagctg tgctgatctc gatctttaca acattatggg
    48361 gtttgctatt agttattcct ggaatcatta aaagctattc ttattctcaa agctatttta
    48421 tttactacga tatcgtccaa gaaacaggac aaacacctaa agtactggat acgatcactg
    48481 caagtcgaaa attgatggat ggttataaag gacaactttt ctggttagat ctttcattta
    48541 tcggctggca tatcttagca ttagcaactg ctggtattgg ttatctatgg ctcagcccat
    48601 acatttctgc aacaaaagca gcattttatg aacaattgcc aaaagatatt taaaagagag
    48661 tgtgacttgt gaccgagggg gtggcaggag aacaccgttt atcgagaggc agtaaaagaa
    48721 acattcagcc cattagcaaa aaggaggtgt gacaacattc atgtcacacc tcctttttgt
    48781 atagttccag taaaaagaaa atcaacttag aaacagttaa tcattcctct tcttctgctt
    48841 ccggtaatcg atggaacttg atcagttcat tcaccgcgat tggtacgata gataaaatcc
    48901 ctaccaagaa ccagtgattc aaactgatgt gtactaggcc gaatagttct tgcgtaaatg
    48961 gcagcaaagc aacagccgtt gtaatagcta atgccagtaa cgccatttct accaaagctt
    49021 tattggtcgc taaattgact ttgaagatcg attggctgct gcgtacattg aacacatgca
    49081 gaatcgatga ataagctaag atcaagaatg caacagtttg accgacatgc tgacttgcgt
    49141 ctacccatgg gctgatagta tcgacataac tacctaaata ataaccaaac aaggttacga
    49201 tggtgaagac ccctgcattt atggcaattt tttgcaataa acctcgagca aagatccctt
    49261 catttttcgg aatgggtggc tgatccatga tgccgtgttc cgctggctct cttcctaaag
    49321 caaatcctgg aagtccatca gcaactacat tgacaaacag tagttgcaca gctgtaaatg
    49381 gtgctcccca tcctaacagc atcgcaatca aaacaataaa gatctccgaa atattacagc
    49441 ttagcaaaaa gttgatagct ttacgaatat tctgataaac cgaacgtcct tgactgacag
    49501 cgtctacgat cgtcgcaaag ttgtcatccg tcaaaatcat atctgcggca ctttgcgcca
    49561 catctgttcc tgtgatcccc atggcacacc caacgttact tgctttcaac gctggtgcat
    49621 cattcacacc atccccagtc atcgctacga ctgcacccgt acgttgccaa gatttgacga
    49681 tccggatctt gtcttctggc gttacccgag catagacaga gagagctttg acacgcgcat
    49741 ctaattcttc gtctgataat tgatgcagtt ctgatcctga aagtgcttct gacggatcat
    49801 tcaagatacc taattctttc gctatggcac tggcagtcac cacatgatct ccagtgatca
    49861 tgactgtttt gatgccagcc tttttcgctc gcttgattgc tcctttactt tctggacgtg
    49921 gtggatcgat cattccgatc agaccaatca aacgtaagtc tttttccagt gcttcagaag
    49981 aaatatcttg cggttcttcg tcataagtag cataaccaac agcaatcact ctcagtgccc
    50041 gtttaccaaa gcgatcatta acgatcgccg cttgttctac atcgcctgaa ctaaagcgcg
    50101 gagcaagaac atcgaatgct cctttggtga ttgagatgta tttttcgccc atttggtgaa
    50161 ctgttgtcat catttttcgt tcagaatcaa aaggaagctc gtttactcgt ggatattttt
    50221 cttctaattc tgcctttgta tgataattct cttcaacagc ccttacgatg gctacttctg
    50281 ttggattacc tttgataaca aggtcgtcat cttcttgctc gaccgtcaca tctgtacata
    50341 gtgcagccat tttcaatatt tccatcgcgc tgttcgtcat tgaatcttcg atattcgtta
    50401 cttcatcttc tttgctccat acccggcgga cgcgcatttc attttgtgtc agcgttcctg
    50461 ttttgtctga gcagataaca ttagcggttc ctagcgtttc aactgctggc aactgtcgga
    50521 tgatcgcatg tttcctcgcc atcttctgca caccgtatgc aagtgtcaac gtaacaataa
    50581 cagtcaaggt ttccggtaca gctgcaacag ccaaggaaat cgaagtcatg aacatctcaa
    50641 ggagtggttc tccttgcagt tcaccaatca caaatactaa agccgcagcc gctaaagcga
    50701 tcatactgat tcgtttgcct agctgattca atcggacctg taaaggtgtt ttttgcatag
    50761 tattttcgtt caaaagatcc gcgatcttac ccatttctgt agccatgcca atggcagtga
    50821 cgatcgcttt cccacgacct gcagcaaccg tacatccttt aaataccata ttaagttggt
    50881 cacctaatga ctcatcttct tcagcaataa atgctgcatc tttttcaact gcttcacttt
    50941 ctccagtcaa cgccgattct tctacacgta attgtgatgc ttcgatcaaa cgggcatcgg
    51001 cagaaatagc atcaccggac tctaaaacaa gaatatcacc cactaccagt tgctctgact
    51061 caacagtggt cactttgccg tctcgtatga cagttgccgt ttgtttattc atatcttgca
    51121 aggattccag tgctttttct gcgtttcctt cttggacaat cgccaatacc gagttgatca
    51181 caacgatagc gatgatcagc agtccttcaa ataaatcccc atgttctgta gcaaatgcgg
    51241 tataaaagga aatcaccgct gctacaagaa ggatgatcgt tgtaaaatcg gacaagcttc
    51301 gaaagaattt tttgatcatc gattctttcg gcgcctcatc gaatttattc aatccctgct
    51361 tttttcgccg ttcatccact tcttgtgaag acaacccagt atctggatct gcttctgtta
    51421 ccttctttac ttcttctatt gtctgcttgt attcttccat cctattcctc ctttaaaatc
    51481 ttcgtacaaa aaaaggtact tattttacta taacatcctt tttttattta cttcaaataa
    51541 agggcttatc gattatttgt taagaaagcg taaaatttaa agtgcttata tttgcaaacg
    51601 ctaccaaagg atgctattat atagatgtaa ggaaggagga taccatcaaa tagacagaag
    51661 aatttctcga tagaacagtg taagcaaaca aagttgttag aagtacaggt ttcacccaga
    51721 catgcgtgta gagtacaaac ctataaatag tgaatgcgta tggatgtttg gatcacgaag
    51781 tatccgaaac aagaagtaat gcgatacgta acaattgaat aacgtaaacg tctgaaaatt
    51841 gaataggaac aagagatgtt tcaaatgttg aagatgtaac gaaaacaaaa tttttgttta
    51901 acatgaagaa attcaacacc gtgctttgca tgtatgatgg aaagttacaa tcatttctgt
    51961 ttatttgaat ccttccgagg tacaagaaag ccgagcttat cgagagctcg gctttttctt
    52021 tgtcataaaa tctttgtaaa gcttttttgt tattcaaaac tagcggcttt tcataacctt
    52081 atttcacgaa catcgcatct ccaaaactaa agaaacgata gcgctcttca atcgcatgct
    52141 ggtaagcaga taaagtcaat tctcttcctg caaaggcact aactaacatg actaaagtcg
    52201 attttggcaa atggaaatta gttgagaaag cttctaccac tttgaattca tagccaggcg
    52261 taatgaaaat atcagtccat ccgctgtctg ctttgatttc tccattaaat ttcgttccaa
    52321 tcgtttctaa tgttcgaatt gaagttgttc cgacagccac gattttcccg ccatttttac
    52381 gtacttggtt caatcgctca gccgcttctt ccgtcaaacg gtagaattca ctatgcatat
    52441 ggtgttcttc aattttatct acgctgacag gtcggaatgt acctaaccct acatgtagtg
    52501 tcagatagac taattcaaca ccctttgctt cgatctcatc aagtaattct ttcgtaaaat
    52561 gcaatccagc tgttggcgct gcagcagaac cattttcttt cgcatagaca gtttgatagc
    52621 gatctgggtc ttccagacgt tctttgatat atggaggcaa tggcatttct cccaatgatt
    52681 caagaatctc tagaaaaatt ccttcatact caaagtcaat gatccgtccg ccgtgttcca
    52741 attcttcttt cactactgct tgcaatctgc catcaccaaa agagattctt gtcccaactt
    52801 tggcacgttt cgcaggtttg atcaatgtct cccacgtatc tccttgtgta ttcgttagaa
    52861 gaaggacttc taaatgcgca ccagtatctg gtttttctcc atataaacga gcaggcagaa
    52921 ctcgtgtatt attcataact agcgcatcac caggctgtaa ctcttcaatg atttcatgga
    52981 aatgtttatc ttccatctct ccagttttcc gatccaaaac aagtaaacga gaatgatcgc
    53041 ggtcttttaa tggtgtttgt gcgattaatt cttccggcaa gtcaaaatca aaatcttctg
    53101 ttgttaacat atcgtcactc actttctatc atgtgcttca tcattctatc atgtttttcg
    53161 ttctgttggc aaaatcagca ctttttcact tctatttttt gttttcctaa ataaaaaaac
    53221 taccctattt gtattttttc attgttttag gcatactagt aatagatagt tcttcattga
    53281 aaatagaaaa agaggtggca ccatgattga atttcaaaat gtgtcaaaaa tttataaagg
    53341 tggaaaagtc gctgtagagg acgtcaatct ttcatttgaa aagggtgagt tcatttgttt
    53401 tatcggtacg agcggaagcg gaaaaacgac gacgatgcgg atgatcaacc gaatgactga
    53461 tccaacacaa gggaaaattt tgattgatgg aaaatccatc caagaaattg atccagtgga
    53521 attgcgacgt cagatcggct atgttatcca aagtattgga ttgatgcctc acatgacgat
    53581 ccgtgaaaat atcactcttg tccaaaaatt gttgaaagtc agtcaagaag aacggaataa
    53641 aacagctgaa aaaatgattg atcttgtgga attgccccgt gagatgttag atcgctaccc
    53701 acatgaatta tctggtggtc agcagcagcg tattggagtc gttcgtgccc ttgcagcgaa
    53761 tcaagatatc atcttgatgg acgagccatt cggtgcgctt gatccaatca ctcgtgattc
    53821 cttgcaagac cttgtcaaag atttacaaga gcgtttggga aaaacgatcg tatttgtaac
    53881 ccatgacatg gatgaagcga ttaaactagc aagccgtatc gccatcatga gtgaaggccg
    53941 tgtgatccaa tttgatacac cagaaaatat tttacgtcat cctgcaaacg atttcgtaga
    54001 agagttgatt ggagaagatc gcctactaca agccaagcca aatgcgacaa gagtcggcga
    54061 agttatgcta aatacagcaa tcacgattac accggaaaaa tcattacaag aagcaatcaa
    54121 actgatgagg gaaaaacgtg tagatacgtt gttagttacc gataattcga atgtattaaa
    54181 aggatttatc gatgtagaaa cgttgaataa aaaacgagga aaagtatcca gtgtcggcga
    54241 cattttgaat aaacatgttt tttacgtaaa agaatccgcc tatcttcgtg ataccttgca
    54301 acgcatttta aaacgcgggc tgaaatacgt gccggtcgtt gatgaacaga acaaagtcgt
    54361 aggtatcctg actcgtgcat cattagtgga tatcgtctac gatgtgattt ggggagaaga
    54421 tcccgcaact actgatgttg cagagtcagc tactcctgaa gaatctaagg aggtctgacc
    54481 tatgcagcag ttttttcatc agcacggttc agaaattctc tcaaaaggtt ttgaacatct
    54541 ttatatttca ggacttgctt tgatcattgg tatcatcatt gctgtaccgc ttggtgtctt
    54601 actgacacgt tttccaaaag ctgccacgat tgtgattggc ttaaccagtg ccttgcagac
    54661 aatcccttct cttgctttat tggcattgat gatcccgcta tttggcgtag gtaaattacc
    54721 tgcgattatc gcactcttta tttattcatt attgccgatt ttacgtaata cgtacattgg
    54781 gatgaaaaat gtcgattgga attatcggga tgtggcaaaa ggcatgggga tgactgagtt
    54841 ccaatccatt ttttccgttg aattgcccat tgctatgcca acgatcatgg ctggtattcg
    54901 tttagctgcc gtttacgtga ttgcatgggc tacacttgcc tcttatatcg gcgctggtgg
    54961 tttaggcgat ttgattttta gtggactgaa taattaccaa ccagatctca ttttggcagg
    55021 tacgatccct gtaacaattt tagcactatt ggctgattgg cttctaggtc tcttggaaca
    55081 ccggctgaca ccgatcgcac ttagagagga gaatgaagaa tgaaacgtat actaaaaatg
    55141 accatggttc ttttctctct tcttatactt gcgagttgtt ccttccctgg tcttgccagc
    55201 aatacagatg aagacaccat ttcgatcaca ggtggaatca cttcagaagc acagatctta
    55261 gcaagtctag ttgccggaat ggttgaacat tatacagata aaaataccgc aatcatcaac
    55321 aatctggcta ctacaactat caaccatcaa gcgatgatga acggagatgc ttcaatttca
    55381 gcggctcgct acacaggaac agatttaacg actacattga accttcctcc tgaaaaagat
    55441 ccgaaaaaag cgtttgctac cgtgaaagat gaatttgaga aaagatacgg tcaaacgtgg
    55501 ttcccgtcct atagttttga aaatacgtat gtctttcttg ttcgaaaaga caccgcacaa
    55561 aaataccatc tatctaaagt cagcgatctg aaaaatgtag cggatgaatt agtagctggt
    55621 gtagatactt cttggatcaa tcgtaaagga gacggttatg acggcttcca agaaacttat
    55681 ggcttctcct tcaattcgat attacctatg cagattggac ttgtttatga cgcagtcgaa
    55741 gcaggaaaaa tggatattgt tcttggctac tctacggatg gacggatcgc cagttatgat
    55801 ctagtcatgt tggaagatga tcgtcaattc ttcccaccat atgatgctgc tccagttgta
    55861 gacaacaaga tattagctga tacgcctcat ttaaaagaag ccttaaataa gttaggtcat
    55921 accatcagta cggaaaaaat gcaggaattg aactacgaag cagataataa tctagtggaa
    55981 ccatcagtag tagcacaacg tttcttacaa gaaaaccact attttgaagg gaagtgaagc
    56041 aattggataa aatgaatgtc tttcaacaat ttttctatta tttccaggaa aatggctcct
    56101 atatctttgc acaatttatc cgtcacttcc tgatttctat ctatggtgtc ctctttgcag
    56161 cagttgtcgg gattccggtt gggatcatga tttctaggag acgtaaatta gcaaactggg
    56221 tgattcgttt ggcgaatatc atccagacga tcccttctct agccatgatc tccattttaa
    56281 tcattggatt aggcctggga gtcaatgtcg tgattgttac tgtatttttg tattccctct
    56341 taccgatcat caagaatacg tataccggga tgatccaagt agacaaaaac atccttgatg
    56401 tcggcaaagg catggggatg actgctagac aacgactatt catggtagag ttaccactct
    56461 ctgtttctgt tatcatggca ggcataagaa acgcgttagt tgttgccatc gggataaccg
    56521 cgatcggtgc attcgtcggt gctggtggtc ttggagatat cattatccga ggaaccaatg
    56581 caacagaggg cacatcgatt attttagcag gtgcattgcc aactgcatta atggcgatca
    56641 tcacggactg gcttttaggt attttggaaa gacggctaga tccagccagc cgtacatcac
    56701 gctgatgtta ttgtaaaaaa caaaagcttc tgcgaccatt tgttggtcgc aaaggctttt
    56761 ttagttctgt catttttaag gcaataatcc actctgattc ttccctcctt atgggcaaag
    56821 agttgctttt cttagctatt tatccattcc gtatactcca acttcatact gccaacgggt
    56881 tcatatctgc atccaccgac taagtttttt tcttatccgc taaggcattt tgccaatcca
    56941 ttttcccatc actcgtcatg gaattcatac cacatgatct ctaaatactc gtctgcttgt
    57001 tctttgaatt gggcatcaat tcttacatcc tttggcgtgg ctttcattta agccttttcc
    57061 atcagtcctc gattgttcga tgccttcagc tgcatcatca aaactggtga ctgccgtatc
    57121 ggtaacttcg atcatctttt atacaatcgg gaacttgcca tcctcatcct tggctaaaaa
    57181 catatctagc cattccagct tctcgccatg ggaggtttgc ggttcctaaa accggtacac
    57241 gattcttatg gactgcatcc gtcgcaacta gacttggcga tacgatgatc cttcaccaga
    57301 agagcacccc cgtaaaccaa ttgatcgata tattgccaat aagaaaagac attggcgtaa
    57361 aagatatcga tccctcgtga tgcattgccg ttgatactgc tattcatggc cgaaagcgcc
    57421 acgactttaa cttcttccgt ttgagtgaca ttcatgttcg gcaatgtcgc tttggatacc
    57481 cgctctgcta aaggaacgac actggtattg tatttcgtat ctgtatcttt tccaaaagac
    57541 catgccaacg aatcctctgg gaaccaataa gacgactccg gttgattgtc cattgctttt
    57601 ttcaacatac ttttggctgt ttctcgataa acgacatttc caattgtctt cgcctcactt
    57661 tggcgataat cgatggtcgt tgccactgcc aacactaaca acgatgctcc aattttactg
    57721 attttccttg tcacacttct tcctccttgt tttacataaa cccgtcaaca ttccattcct
    57781 aaactcaaac aatgaccctt caaaggtgga gatataggaa caaattaaag aaatcatgca
    57841 ataaatccaa gaaggttggt tttagaacaa aaaaagagtc tcctttttgg ggagactctt
    57901 tgttaactat ctaaaaaggt tggctcttct cacttcactc ataatgtgtc caggcagaat
    57961 atatttctac aactttattt tcctcatcaa ctttgtaaac cactcgatgc tgtctattca
    58021 gcctgcgtga gtatctgcct tcatgtgtag gtctcagctt ttcaaaagac tgcgtgggca
    58081 tatatggatc ttccttcaat gtctgaatca cttcttcaaa ttgtttcttt aaattcgttt
    58141 gcttgatttt tcttaaatcc actttcgcag agtttttgat tgcgactgta tagttactca
    58201 tcaaagagct tcccaatcaa tatcatcgat attcgtaaag ctactgtcgt ctttttcgcg
    58261 gtctcgtact ttatctaaag tacctgtttg ctcaagaaaa agggtttctt gaatcgctct
    58321 ccagtcttcc agcccaatca atacagcatt gtttccacta cgatcactaa taatctcgat
    58381 ttcagtatga ttttcattta cctctttcaa taactgataa aaatttttac gagcagtgct
    58441 aggattcatc gttgtattag ccattgtctc tcctcctttt tctgatataa ttatagcgta
    58501 cttgattaag tacgtcaaaa aaatacaata aagcacttaa attcagcaaa cttttcctct
    58561 tttttacata gagaaaaaga ccccttttta gggaggatct ttgtccacgc tcacttctta
    58621 ctcctttacg actagcggta gccaaacgta aagtaattgg taacaacgta tcatctttag
    58681 caaaggtcga atccaaagcc tgtgagtcta tgcaacaaca ccaatacacg aaggttcctc
    58741 gttgcagtgt gacttgattg atatcttgaa taacctgagg atacgcacga aagatttgta
    58801 acggttattc aaaactgatt ttggccgtca agtcttctac tgcctcaaaa atgattgcct
    58861 ctttcgtctc ctgtcattca tgttcactat cgatttgata cttgcttaga ccgttgggtt
    58921 tgtgaatcac caattaaaaa tggcactgag ttatggtaac aaaaaatggt cacttgacga
    58981 ggctgagatt cctacttatg aagacacatg gcacttaaga gtcgaggtaa aggaagaagc
    59041 tgaaaatata ggaggctgta cattatttgg caaaggattc ggaaattatg atcaagacat
    59101 caaaatcaaa atgttttaca gctaaatagg aagaataata acatttcata cgctgttccc
    59161 atctttaatg gcttatagag ggcaccttta gctgagaata agacaaaaca gaccctctag
    59221 cttcaattaa gagctagagg gtctgttttt gattttaaaa cttggtttat ttcttcaaat
    59281 ggtagctata ggtgctgaca acgatatttt cacgccaaga caatcgcaat cttaaccgca
    59341 aacttgtttg gttatggaga atattctgcc agcgtctgtt tggtacaaat tgaggaatca
    59401 acacagtagt tgtatagttt tgtttcgctg catttttact tacgatatct acataacgga
    59461 taattggatt ttcaatcgag cgataagaag agtggacgat tgaaaaacgg acatctggga
    59521 aatgcttttt aaattctgct tcgatttctt tttctttttc gacatcttcg tctagcgaaa
    59581 catgcatcgc aacgacataa tcaccgatcg aacgtgcgta attcaacgca ccgatattta
    59641 cccgtgtcac attcccgact aatacaagaa cggtattccc gtcataatca tgtagttttg
    59701 catcattttc taaacgaagc tgttctgcta cttttttata atgatcatgg atcttataaa
    59761 aaatgaacat aacgattggc ataatgatga agaaaggcca aatgtcccct aaccgataga
    59821 caaacaaaat cgcaatgatt gcatatgaga tgaacgcacc cgtaatattg gcaatcgatt
    59881 tgcttaacca tctttttcct tcttttttcc atttgacgac catccctgtt tgagataaag
    59941 caaatggaat gaacacgccg atagagtata acggaatcaa gcgttctgtt gagccatgga
    60001 aaataaacag caatacgatc gaacctagcg ctagtgtgat aatcccattg gaatagccta
    60061 gtcgatcccc acgatcttga tacatgtgag gcatgaattt atcttttgcc agattgtatg
    60121 caagaactgg aaaagcagaa aaaccggtgt tagcagcaac tgctaaaatc agcgctgtag
    60181 caaattgaag gacgtaatac aaaataccat gtccaaagac agctttacca atttgagaca
    60241 aaacagtgac ttctttttca ggaacgatcc cataccaata gttgataaat gtgatcccca
    60301 cgaagaagaa acctaagatc aatgccatca tcgtcaatgt agcagcggca ttttttgctc
    60361 ttggcttctt aaagaatggt acagcattac taatcgcctc caccccagtt aaagaggaag
    60421 aaccagaaga aaatgctcgt aaaatcaaag cgatagaaac acccggcaca gccgctcctg
    60481 gaagtgcagt agcttgcaat ggcacagcac ctgtcacgat attatataaa ccaacaacga
    60541 tcagtaacga gatcacaagg ataaatgtgt acaccggaaa taataggaac gatgcagatt
    60601 ccctcagccc acgaagattc agcatcatca gtagcaaaac gattgtcaca gaaatagcga
    60661 cttgatgacc gtagagtgct ggcaccgctg atgtgatcgc ttcagcacct gctgagacag
    60721 atactgctac tgtcaacatg tagtcgatca ataaagagcc accggaaatc aagccagcat
    60781 tctttccaag attctcactg ctgacgacat atgctccccc gccatgagga taagcatgga
    60841 tgatttgacg atatgatagc gttaatgaaa tcaataaaat aataacaaaa gcggcaatgg
    60901 gtagcgaata ccagatggct gcagcagaca aagcgactaa aacgacaacg atttgttccg
    60961 taccatatgc aatagatgat aacgcatcag acgacaataa tgccaaagca gcaaatcggg
    61021 ttaatttgtg ctcatcattt tcagcagatt ttaaaggctt acctactaac aaccttttta
    61081 agtaatccaa tttctaaact cctttacaca caattttact tcaagtttta tagtcgaaaa
    61141 tttatagtaa acaagatgtt atagtacgct cactgacctt aaaagtcaat aaactttaag
    61201 aaaataattg gaaaaaaaca gaaaaatatc aagcgctttt tcaaacgctt taatacagca
    61261 aaaatctaac atttttttat gggctttttc tttgaattct ataataaaag gatagaactt
    61321 gacttagaaa atcaagttct atcctttttg atatcttaac ttttggaaga gagatgtaag
    61381 gctgctttct acccatcatt cttactactc gaagcatagc gcagttgtca caacctcttg
    61441 ataaacggtg tttaaaagct tgcatctgcg gtaataagcc caaccaaatt aaaaacataa
    61501 gaagctgttt ttatttggtc gttcttatta cttgatgcag agcagctttt ttacaacctc
    61561 ttggtacacg gtgttcaatc agctgaccct cggtattagc tcaaaaaaac ggcaaaatat
    61621 gaggaactat ttttccattt ttttctctaa tactcaggtc aaaacactga tttcacaacc
    61681 tcttttttta atgaaaaata tggctctcat gcgccgcttc tttgaatttc gtcatttttt
    61741 cttcgatgaa cggatagatt gccgttccta cgattccaaa gacaacaaac aaaccgatca
    61801 tgatccagat tgctttcgta gcatttggcc aataaattcc tcctgcagat tcccgtaaca
    61861 agtttaccgc atgagtaaat ggcaagaacg gattgatcat ttggaagaat ttccctgaga
    61921 cttggatcgg atagttcccg cctccgccag agatcgacag tactaagatg ataatagcga
    61981 tccctttacc gacattatcg aataatgcag ccaagacata gacgatcatc atgaacgcta
    62041 aggcgatcaa gacagcaaat gacacgctgt agaccggatt ttggacatct actcctagta
    62101 agaaaatatt ccctaatgta acgatcaagc tttgcgcaat cgccattgtc aaaaatgtca
    62161 gcatacgagc aacgaattgt tctcgtttcg taaaattgtt tcggtctttc tttcctaaat
    62221 agtattctgt cgtagcaaca cttgaaagaa gaacagcgcc gacccacaga catagtgcag
    62281 tataaaacgg ggtgctagct gaaccgttat ttgcgattgg ataaagcgca ttggtttgta
    62341 gctcaacagg ttgtgtaaag aagtcacttt cttttgttgc gtctagtttc aataatttga
    62401 tgacttcgcc tagatcgact tcttgttcgc cttttcggat cgcgtctgct gctttttgga
    62461 taccagcttt gatatttggc cagtcattgt tgatcaagtc cgcagcagcg ttcacagctg
    62521 tttcgacttc tggcattttt tcatttactg ttgtcaatgt accggtgatt tcatttttta
    62581 gtgctggcca atcattttgg ataaaatcag cggccaatcc taatttttgc tgaatgatcg
    62641 gtaattcatt gttgtatagg tctgcccctt cattgatgcc attgacgatg gtatccatat
    62701 ttccattcag cattgtattg gcatcatgga tttcttgtcc aattgcaggc atttcttttt
    62761 gatatttttc taaaattgcc actgcattcg ttacagttgc tttcgttgag ctgagaagcg
    62821 aatcaaagtc gatctggtcc gctttgctca gtgcgccttg tgcagtccca atcgtatcga
    62881 tgacttggtc tagtagagaa gtgacagtgg aactgatttg acctgtattg ataccagcaa
    62941 tgatgccatt gatattatta acaacggcat caatttgatc tagcaattca tcaatagcct
    63001 tcgtgtcttc attttgaaca gctgtgttca aagcagatag gcggttttgc agattgctta
    63061 gcaagggttt taattgattt agctgatcaa taattggctg taatttcgta tttccagcac
    63121 ttgtttgcaa tttagtcagg aactcgacca gtttatcgat tgcattttgt tgttgagata
    63181 ttccgtcaat aaagccgttc aatacattgc tgatgttttt cttttcatca tcagtcagct
    63241 taccatcttc aatagctgtt cttacagtat ctattaacga acctgtcgtt gttgccactt
    63301 gtccaattga cttcaatgta acatctacac tgtttgtgat gcttggtatc gcatctttca
    63361 gctgagaggc acctgatttt gtttggtttg ctagatcact tgcctgattt tctaaatttt
    63421 tcacatctgg caagatatct tgtacttgtt ggatgatcgt caagccttgt tttgcttcat
    63481 cgattccttg gttcattgtc tcttggatcg aagcaaaatc gccgtcgatc tctgctagtt
    63541 gcttaccggc attttggatc tctgggattt tttcttgcaa atcaaggatg atttttgctt
    63601 gatctttcaa ctcaggcatt ttgtcattca atgcaacgac tttttcaccc atctcatcta
    63661 ctttagggat gtaatccacg aattcatttg ctttattcag tttttccttg atttcaggta
    63721 gttgactttg taattcgagg acttgttttg tgtagccgtc gatcgtgtcc aaattttcat
    63781 ctgttgataa aatcatatct ttaactttat tgatacttac taggttcgta tcgatgtcgt
    63841 aacctatctc attgaatact ttcaataaag tcgaactggc tgttttgata aattcatttg
    63901 tgatttgcga ttggatcgaa cttgctcctt tatcggtgat tttcggtgca atcgcattga
    63961 ttttttcatt taccgtatat tcgatttttg gtttcttgat atcaccacta gtaaaactca
    64021 gcagatcttc tgagaaatcc tttggcaagt aaatacctgc gtaatacttt ccggaacgga
    64081 ctccgtcttc taattgttct tttgaatcaa cgaattgcca tcctaattgt ttatttttat
    64141 gaagcgattc gatgacttgc tccccaatgg ccacttcttt accttgaaac tctgctggct
    64201 tgtctgcact gtaaacagca attggcagct ctccagtatt tccatatgga tcccataatg
    64261 ctttgatgtt aaaccacgca tatagcgaag ggatgatcat gatcgcgatg atcagaagtg
    64321 ttgcaatcgg gtttttgaaa atccgtttcc agtcaagcaa atataatcga agcgtatttt
    64381 tgattgactg catagttctc ccccttcttc ttttttcagc tgaattactt taccatgtat
    64441 ttcatacttt tttcaatcgg cttttttcaa aaaagtcgaa tttttggaca tatcacggca
    64501 attgtctcat tgtaatctct tacatattga gaaataatta aggattacag cctttacttt
    64561 atcatgaaat aaaagggaaa gataatttta tgccaaagtt tttatctatt atacgtatac
    64621 gcaaaaaagc taaaacattt tttgtctttg cccctacaaa aatgtttcag cttttttcgt
    64681 tttttattcc tgtatttctt atttttcgaa tgacaggatg attttcccag caggaggatg
    64741 tccttcaact agctgatgtg cttggatgac atgcttaagt gaagcagaca gattcattga
    64801 aataaaaaca tgaaaggctc ctttttggta ggctttgatt atgccagcaa aggcttctgc
    64861 atctagatat tcctttcttg gaacaaacga ttcataaaag ccttcctttt tttgccgcaa
    64921 atctagatct gggaggtcat ttaatgcaac atacctgccg cctggtttca tgatctggat
    64981 gccggtttct cctttgatac ttcctttcgt cgcatcgatt acaaggtctg cctgatcagc
    65041 aaattgcaga cctggatttg ttttatcata agcagcaaat gctgaagctc ctaatttttt
    65101 taccttttcc tcatttttac tggatgcact ggttaagatt cggattccct tttcatggag
    65161 aagctggatc agacttgacc cgaccgcacc tgatgctcct agtatcatta cagtatctgt
    65221 cggctggatt tccgtcaaat ggttgattag attataagcc gtaattcctg gcgtgaccat
    65281 tccggctgct tcttcccaac tcattttatc tggaattttt gctacttttg ctgatggcaa
    65341 cacgacttct tctccgtaag tcccgccgac tgcatggaca gctactcgat cacctacatg
    65401 aacagttgtg acatctgaac caatctctgt cacaatacca gcgccatcat tacctggtac
    65461 ataagggaat ttcaatgttc gtatctcttt catttctcct aaacgcaagg caacatcata
    65521 aggattcaca ctgaatgctt ttatttctac acgaacatgt ccagaaccga cttctctggg
    65581 atgagcatcg atttcttcaa aaacatcttg tgcttctccg taaccgttaa ttgcaaatct
    65641 tcgcatggtc accatctccc tttttcttta agtttacgtt tatgccttta ttttgacaaa
    65701 aaaaatgtct tttcgttttg gcgcatgatt caaaacaaaa tagttgtctt ttttcgcgta
    65761 acgtgttaaa ttatttatct aaaagcgtaa agattacgat ttacgctaat aaaaaataat
    65821 tggaggaatt tgttgatggc taaaaaatca aagattgcca aagcaaaaaa acagcaagaa
    65881 acgattgaac gctatgctgc tttacgccag gaattaaaag cgcaaaaaga ttacgaaggc
    65941 ttgcgtaaac ttcctttaga tgctcgtcca gaacgattga aaaatcgtga tttaatcgat
    66001 ggacgccctc gcggatacat gcgtaaattc gggatgtccc gtataaaatt ccgtgaatta
    66061 gcacataaag gtttgattcc aggagtaaaa aaagccagct ggtaatccaa gtctggctgt
    66121 aatgtaaagg aggagggcgc atggaccact ccttggatca tcaaaaaaga tacgttcgct
    66181 tcttctagca gaaatgctgg tactagaagc agacgtatct ttttttacgc acagctggtc
    66241 cttttttata tgtaaaggct gcatggttac ttcgctatat ttatttagta acaggagtca
    66301 gtgcttcgat acccacacta attttcaatg ctcggtcaac ttctgccata atgggtcgat
    66361 ccaaatggca gaccttttct ttcaatcttg atttatcgat cgttctgatc tgctccaaca
    66421 ggataacgga gtctctttct attcctgttc cagtagcttt gatcccaatg tgagtcggaa
    66481 gcttaggttt agccattttt gccgttatgg ccgcaacaat gatcgtcggg ctaaaatggt
    66541 tacctagatt attttgaata accaaaactg ggcgtgttcc gccttgctcc gatcccacga
    66601 ctggagaaag atcagcaaaa taaatatctc ctctttttac cataggatcc tccttattct
    66661 tgatattctc ttggtatccg ctgtcctaat ccgcaagcca cttcatagtg gatcgtacct
    66721 aattgatctg ctatatcctg catagtgatt tctttgtctg catttttgcc gataagcgtc
    66781 acttttgttc cgacaggaaa ttcttgaggc aatcggatca tcagttgatc catacataca
    66841 cgcccaatcg tttcacagta gttcccttct accaatagag aaaaaccctg catctttcgt
    66901 ggccagccat ctgcataacc gatcggtatc gttccgatcc actctgcttc aggagtgata
    66961 tatgtttctc catagccgat tccttcacct gctgggagtt ttttgacttg aatcaattca
    67021 gaaaccagct caagtgctgg ctgcaatgga taaacttccg gtagtgcgtg cccagaggga
    67081 ttaagtccgt acattgctac tccataacga atcatattgc cgattgtttc atcatgccat
    67141 aaagccgttg cactattgct gacatgtaca tatcgaggaa gttcgggaag ttttttcagc
    67201 acttctataa agcgttcttt ttgcagattc caatatgtat catctgcctg atctgctgta
    67261 gaaaaatggg taaataaacc ttcccattct aatacacgac tttctttgat gaatgcagct
    67321 gcctctttta cttcttcagg tgtacaaaat ccgatacgac ccatcccagt gtctgctttt
    67381 agatgaatcg aaagaggcgt ctctagctta cttttctcta aaacagcagc tgctgcttgc
    67441 aaccattccc gtgtacctgc agttactgat aaatcatgag caacagctac agtcagtgcg
    67501 tcgtaaggaa ccatattcaa gataaggatg ggctgagtaa atccagcttc tctcaactcg
    67561 actccttcat ctaaatttga aacacaaaag cccgaagctc cacctgcaac tgctgcctca
    67621 gctgtttcaa tagctccatg accgtatccg ttcgctttta ctactgcaaa caattctttt
    67681 ccttgcggaa gtcttgcaac ttcatttgct acattttcag ttatagcttt tttatgtatc
    67741 actgctttcg ttgggcggtg ccaagcgaca accatcgttt ttccttcttt ctagtcttcc
    67801 aaaataattt gtgcaaaagc tgtttcattt gtatgagtaa tactgaccca tacattgcct
    67861 tcatgaggtg aacgcgtcac aacaggctga ccattttcat tttttaaaat ctcgacatct
    67921 tgaaaggtaa cttttccgat cccagttccc caagctttag agaaagcctc tttgcaagcg
    67981 taacgcccgc ctaaaaattc tacttggcga tgaaaaggca aggactggaa tagtttcatt
    68041 tcatcagagg tcaagattcg tgcaatgaat tttggttttt cttcgatcag ccgagtgatc
    68101 ctaggaagtt cgactgcatc gatcccaatt ccttttatca tatgcttttc tcttttcaat
    68161 aaatttagaa cactctcatt ctaccaaatt ataaccattt tgccacaaat aagtccacaa
    68221 ataacaaaaa tgaaagtttc tcttaaaaaa gagaaacttt cattttatgt ttaatcgtta
    68281 tttgaacgga ttacaaatcc gcgtttttta tcattgtgac gtttaccgcc atctttttgg
    68341 ctgttattat ttttgctata accgcctttt gatttgtttc cacgataatt accgccgtca
    68401 cgacgattac ggttgtttcc gccaccacgt ttgccatttt tattgtatcc ttttttctgc
    68461 attggcaatg ggcgttctgg tgtgatcttc actggcactg catcagctgg atcttttgct
    68521 gtcgttttta gcaaaagtgc aactaaatct tgtgcagaat attcttctaa taatttatct
    68581 gctgtttgca ggtatttatc tagaccattt tctgcaagtt ttgtttcgat ttgttcaact
    68641 gcagcaccta attgaccttt gaatgcttct ttttcggttg gtggacgtaa agtcgtcatc
    68701 cgttttttcg tcaagttttc aatcacatgc aagtagtcca tttcatttgg tgtaacgaaa
    68761 gtcacagaca taccgccttt tccggcacgg cctgtacgtc cgatacggtg aacgtagctt
    68821 tctggatctt gagggatatc atagttgtac acatgagtga cacctgaaat atctaatcca
    68881 cgtgcagcaa cgtctgtcgc tacaaggata tctaaatgac cgctcttaaa tgaacgcaat
    68941 acgctcattc gtttttgttg agacaaatcg ccatggattc cttctgcacg gtaaccgcgt
    69001 gcttctaatc cgcgtgccaa ttcgtctaca cggcgttttg tacgtccgaa gacgattgtt
    69061 aattcaggtg tttgaacatc aaacaagcga gtcatgatat cgaatttttc gtattctttt
    69121 gcgcggacat agtattgatc gatcaagtca gctgtcattt ctttcgcttt gatcttcaca
    69181 tgatgtggat ttttcatgaa tttaacgcca atattcttga tagctggcgg catcgttgct
    69241 gagaaaagta atgtttgtct ttgatcagga acttgtgaaa tgattttttc gatatcttcc
    69301 aagaagccca tattcaacat ttcatctgct tcatccaaaa ctaatgtttg aacggttcca
    69361 agtttcaatg tgtggcggtt aatgtggtca agcatacgtc ctggtgtacc cacaacgata
    69421 tgtggacgat ctttcaagcc acggatctga cggccaatat ctgctccgcc gtaaacggct
    69481 tgtacacgta cttttttgtc gcgccctaaa cgatataatt cttcttgtgt ttggatagct
    69541 aattcacgtg ttggtgcgat aactaaacct tgtaattcgt gacgatctgg atcgattttt
    69601 tctaacattg gtaatccaaa tgcagctgtt ttccctgtac ctgtctgtgc ttgtccaata
    69661 acgtcttttc cagctaatgc tagtggaatc gtttctgctt ggataggcgt tgcttcttca
    69721 aaaccagcgc gttcgactga tttcaacaat tctggtgata attctagttc tttaaatttc
    69781 aaatgaatcc tcctatatgg ttgttaactg aggatgtagc ttttttgcta ccccgtcgat
    69841 ttgttcggtc aaagtgtatt gtttcttttt gacagtggcc acgcacgttt ttatccattc
    69901 ttagcccctg tggcaccacc gaaaaatcac tttgcgaagt ttaggcatta gaaaagccaa
    69961 acgggtcgcg ttcagcttta tcattattat gacatctggc ttcaacaagt tgtttctatg
    70021 gcaaaaccag tccaatttct cttcatcttt cggcaatagg ttattctaac atagtttttc
    70081 gttttctgca agtttacaga tttttatttc atttgctgaa gttgttctac cacttcaaat
    70141 aagcccatgc tgttgctgcc ttttagcata atactatctg ttgcttcaag attttgtttg
    70201 atagcatcaa tcaatttatt cttttctttt tcaaaataga acacaggtag ttgggggtat
    70261 ttttggttca attcttcttt tagtgcatgc atttgttccc cataaaggaa aatcatggcg
    70321 aatttctcag gatcgatatg ttcactcatt tgcgcatgca tatttaaaga ctctttccct
    70381 aattccagca tatctgctaa cacagcgatt ctgcgtcctt ttgttggcag atttttaaaa
    70441 gtatctaata ccagtcccat ggctgttgga tttgcattgt agacatcgct caaaatagct
    70501 gcaccatttc ctgccgttag ccattcggtt ctgttttgag tgatagaaac atgggcgagc
    70561 ccttggcgta tctcaggtat ggacagtcca aagaagcgcc cgatcgtata cgcaatcaaa
    70621 gcattcgtta cattataact tccaggcagc gggatcgtaa atgtttctcc ttctactaca
    70681 aaatcggttt gtgcttttcc ttttgctgtc acttccgcat gaacatcgcc atttccaata
    70741 ccgaatgttg tgactgtttg tactaatgtt gccgttaaag gtgtcagcaa cggttcatct
    70801 gcgggcacaa cgagtaatcc gtctgataca agtccgtcag tgatttccat tttggcttta
    70861 gcgattcctt ctcgcgaccc aagattttct atgtgtgctt caccgatcat tgtgattgct
    70921 gcagcttttg gttgagccat aagtgaaagt tccgtgattt cattggcgtg atccatgccc
    70981 atttccaaaa cgatcttttc tgtatcttgg ggcatgtgca aaatcgtgta aggaagacca
    71041 atattattgt tgtaatttcc ttgcgtctta tatgttttgt atttttcaga caagacagac
    71101 gcggttagat ctttcgtggt ggttttacca ttgcttcctg taattgcaac gacttctgcg
    71161 cctacttttt ccaagtaata ggttgccaat tgctgcatgg ctttcaaagg atctgctaca
    71221 ggaataactg gaaaattttt tggagcttgt tcaacaggca agctccaaaa tgaagcagat
    71281 gctccgtttg tgatcgcttg ctggataaat tcatgtccat ctcgcgtacc agcaagagga
    71341 acgaataaac ttccttcggt tatcttccgg ctgtcaaatt cgacattggt aatctttgtc
    71401 agtgcagagc attcgctgcc cacggcttgt gcaatttctt gtattgttag attcattgag
    71461 atctctccta aaaaaggttg tgaaaaaagc gtttggccta aacggcgggt tcgcatgact
    71521 ctcacttcca agtaaatttc tctattcgta tttagaagct agaatgaacg cggttacgca
    71581 atcactccag cctcttcttt atttctcttt attcattttt ttcaaaaaaa gattgacgct
    71641 gatggtatcg attcattcct aactggatca gttcttcaat caaatcaccg tatttcaagc
    71701 ccatattttc ccataagagt gggtacatac tgaactccgt aaatcctggc atagagttta
    71761 attcattcag gaataattca tttttatttg tcaaaaagaa atcgcaccgg ctcaatccgc
    71821 ttccacctaa catcgtgtaa gctaacttcg cgtactcttg cgctttttga taaacttctt
    71881 ctggcacttc ggctggaatc tgcatttcga ttttattatt gatatatttt gcttcataat
    71941 catagaatgc tacgtctttt acgacttcac caggcaaagt cgtccgaacg tcttcatttc
    72001 ctaatacagc aacttcgatt tcgcgcgctt caattccttg ttcaacgatt gctcgagaat
    72061 catactgata ggctgttgct aaagcatttt gcagctcttc tcggttttct gcttttgtaa
    72121 tgccgacact agaacccata ttcgccggtt tgacaaacat cggataaagc aaagaacctt
    72181 cacattgatc aaatactttt ttaggatttt ctttccattg attcttaagt actggtacat
    72241 aaggaacttg cggcacacca gcagcttgta aaatatactt ggtcatgatt ttatccatgg
    72301 cacatgcact ggtcaatacg cctgcgccga cataaggcat attcaatgtc tctaagaagc
    72361 cttggatcgt tccatcttcc ccgtttggcc catgtaaaac tggaaaaacg atggctcctt
    72421 cttctttgat ttcgcccgga ttgatcactt ttcctgtaaa gccttcctct gtctgtccac
    72481 ttgggtccca tgaaagatgc aagacatctt tgctggcagg tttttctgtt agtaatggac
    72541 ctttgaccca ttgtccttct tttgtaataa atacgagttg aacttggtaa taattataat
    72601 aaatggcatt taaaactgaa aatgcggaaa gaatggacac ttcatgctct gcgctgcgtc
    72661 cgccatatag taaagtaatc ttcaaaagat tgtcctcctg tattctaaat cgttcagtga
    72721 tttactctca tattttagca caaaacaaaa ataaacgaat aacttattta taaaaaaacg
    72781 agccagcttc taaaagaacg agcgtcattt attttttgtc agctagatta tttgtcccgt
    72841 tttttataaa aagttatgat aaagaaaagg agggatgatg atggcgcaaa caaatccacg
    72901 cagccgcttg gcagaaatca ttcgagtgtt catcaattac aatgtagtgc caaactttgt
    72961 acagcaaaaa aatcccgaac aggtaaaaaa agcctttgaa gaactaggcc ccaccttcat
    73021 caagatagga cagatgcttt ctgttcgaga agatttgctt tcttctgcct tcactcaaac
    73081 attcaaaaca ttacaagata gtgtacctag cgacacattt tcaacggtca aaaagacgat
    73141 cgaaacagaa ctttctcttt cattatcaga tatattcgat gatttttcaa aatcgccttt
    73201 tgcctctgct tctatggggc aggctcatcg tgccaagctg aagaacggtg acgcggtagt
    73261 cgttaagatc caacacccta acatcgccga agagatccga cttgatcttc aactatttga
    73321 acgagcgatc cctttgatca aatacattcc tgaaactagc gtagttgatc taaaaggggt
    73381 actccaagaa gtaaaacgtt ccttgatcaa tgaaatggac ttcttaaaag aaagtcaaaa
    73441 tggcgaacaa ttctatcaaa agaacaatgg ctggaaagag atccgcagcc ccaagattta
    73501 tgacgctttt tgttcgaaaa aagtgatcgt gatggaagaa atgtctggta aaaacttgaa
    73561 tcatttaatg aacgccgaaa acaaaactga aacttttatc actggaattc aaaacaagca
    73621 gctgaaacaa gaagttgcaa agcttttagt tgagaacttt atgaaacagg tgtttgatga
    73681 tggttttttc catgctgatc ctcatccagg gaatctgcta ttccatgtac taacaaaaga
    73741 agaacagaca caagctagcc gaaaaactga aacagtccat gaaaaagagt tcggttcctt
    73801 tgcttttcga gcctccactt ctgcagaaga ccctgttgcg ccatatacca tcaactacat
    73861 cgattttggt atgatggggc atctttctgc aggacttagg caaaaactca cacaagccgt
    73921 tttagcgctg tatacgaaag atgcttatcg aatcgaaaaa gcggtccttc gactttgtca
    73981 gcaagaaggc tcgtttgatg aaagtcggtt ccaccaagaa ctgacaagtt ttcttgaaca
    74041 gtattatgat tctcctattg atgaaatcaa cttgcaagaa gtattcacac atgtcgtgac
    74101 gatttgtcat caaaataatc tgcagttcga tcgtgatatc acgcttttgc tgaaagcatt
    74161 tgggacatta gaaggggtga tccgcgtcct cgatcctgaa gtttccctca tggaagtcgc
    74221 ttcgcctttt gctcaacatt attttctcac tcatctggat gtagaagata cattgaaaca
    74281 aagcggatta gacttattgg aagggatgaa ggctgcgcct aagatccctc aacagctcca
    74341 ccatctatta gaaatgtgga cttcgggaca aggaaaagtc aatttggaat tgaaaaagca
    74401 agacaaatta ttgagcagga tcgaaagtat gatcaatcgg cttgttttcg gtatgatttt
    74461 agctgcattg atcgtagggt cctccctgct tgtccaagca gcacctgtag aaaacgcaga
    74521 ggtcgtttcc ttattaggga tatttacgta tgctattgcc gcattcgtca ttattttttt
    74581 ggcaatcgat gcattgatcc aaatgtataa gaagaggaaa aagtagaaaa aggttgtgac
    74641 agaaagaatc agcttcaaga aataagaagg ggttttacat aaattgtttc tcaaattttt
    74701 gtgaaaattc ggcttatttt tcgaagaggc tacttctgaa acaccgagaa taaaaaatgt
    74761 gaaaaagctg ttctgcaccc agtaataaga acaatcaaaa agggaacatg gaacacattt
    74821 atcctgtttc cctgttccct ttttgatgta ttcgagcata aataaaatac cttcgttacc
    74881 tactatcttc tgtacttggt aaaccttagt caattgcctt ttttaacgct tgacgaaaag
    74941 acatatgatc tttctccgta aagggttttg gaccctttgt ccttatgcca gcttttctta
    75001 actttccact atgataacgt tgttctagaa gcgtgccgat attcgcttcg tcaaattctt
    75061 ttccagagtg atggaacact cgcacaccct tcggcaatac aagtgaagct aaaccataat
    75121 cttgcgtgat caaaaagtca ttcttcttaa ccataccgac gattttataa tccgcactat
    75181 cagctccgcg gtctacgtag acgatttgga catgattagc gtattctttg gtcgtataat
    75241 ggtccacact ggtcacgata accacgtcaa gaccatagga ttctcctaat tttatgacat
    75301 cttcttttac tggagaacca tctccatcaa tgaatagcct cattcttttt cgccttcttc
    75361 cataaatgat aaacagttac taatccgctc agtaaaagac caacattgat ccattttgcc
    75421 aagataagca gttgtacact ttctatcggc actgattcat ggttcagcgt gatcaataat
    75481 agatggattg gctctcccat ttcttttgct aaaacaaaca aaagcgtcat caataaaaac
    75541 tggtggatca cactcccttt attttgagta gtatacttga caacgatccg gcgatccatt
    75601 ggaatagctg tatcagtttg ataatattcc ttatttagcc agctgcctgt tactacgtgc
    75661 cagaaactaa gcagaaagac acctatcgca aaaccatttg gaatcaagag gaccaataaa
    75721 gaagaactca gtccaagcaa ttgcatagcc aatggagacc atgttaaacg tttcaaaatc
    75781 catggtccga ctatttttgc tgcaatcaag cctgctgcat aaggcaaata cataaaaatc
    75841 gaaagttttt ctaatccgta cagtatgcca acataaaaac tgctaaataa aaaaaggaaa
    75901 ttccctagca ttccatttag aaaagtaaac agatttagcc agcttggcaa cttccattcc
    75961 ttcttctggt gtcctaaaac aaacacgaac aagatgaaca gcagcaagaa accataaata
    76021 gcaagatcaa aaagcctttc atcgaataac aatcgggcat ttctcaaaag aaacaataag
    76081 ccaaagaata tcaaaaataa aacaagctct cgcgtagcta ccagatttct tttgatgtct
    76141 ttgaaatcca gttcgtaacg cggataatga ctaaccgtat ggtaggccat gacgtaaaaa
    76201 agtgtataaa tagtaaagct tgctgcaatc tgagtcggtg caggcaactc aatcgcttga
    76261 tacaggagaa atagccagat agctgcaaat aagtactttt tcccatccat attgataaaa
    76321 ccttgcgtct tttcgtgaaa attgaccgtg gtattagcag gtacaagcca tgctgcactc
    76381 agccctagca aaacacttga aaaataaaat aaaggaaaat aaaatacgcc taatattcca
    76441 agcaatgaac cagcaccacc aatcagcaga gcgatcatca gcaacgtgta actatctaga
    76501 ccaaatcgta gactgttgac taaaaatagt ccagtcatcc gaaaggcata aaacagcgta
    76561 aatggcaaaa tcgtcagcca attatgcgag tctgttagtc ccaaaaataa aagataagga
    76621 ataaaaataa ccgtgttact taagataaag ggcgttgttt gtgtaaaatt acgcccaaat
    76681 cgtttgagtt tttcgaacat gacaatggct ccttaaacag tcttataact aatctgctct
    76741 tcgattttag cattaaaggg gaaataaacc aattttacag aatatattct tgtaaaaaaa
    76801 aatacagaaa gaagcataag cttctttctg catttttacg gtacttgatt actcaagcag
    76861 acaagccctt ctccacaaaa gtcttgcccg acacccctgc atccggcagg tgataaagat
    76921 agaaatcaat tatcctgtgc ctccaaaatc aattaggagc tctgtaaacc agagtccttc
    76981 tcgacccgtc gcataaattt actttaacac agttcctatg tttatgcgag agcttttttc
    77041 attttataat cgaccatttg aaatccttga ccgatatctg aaataagttc ttctgtaatc
    77101 tcaaatcctt catgcttata aacctcgatt gcttgatgat tcccctgatt cactcgcaaa
    77161 aagatctctc tttcctttgt ttgcgcagca agttcttcat accagcgaaa aactgaagaa
    77221 gtcaatcctt gaccacgtac tttatttagc aaatataatt tacttaaata aatttttcca
    77281 tttatctctt cataagcagt gtaaccgaca gtcttttctt cgctttttaa taaaaagtag
    77341 gacacacctt ctgtcagttc tttttgaatc tgtttttttg actgataagt tttcagcatg
    77401 taatccactt gtttttgacc aatgatcggc acaaaaactt ccggccatac ttcttgtatg
    77461 actgccatca gctcatccag ttcattttct gttactttta ttttttccat acacccacgt
    77521 ccttttttac attataaatg accttgcgct tgatggaata aaaagagcat gatcatgcta
    77581 tacacaccca ccgaccacgg tttcaagaaa atcacaatct gcataaattc cctaaaagat
    77641 aatttcgtca aaccagctac tagacagatc aagtcgtctg gcgcaaaggg aagcagcaag
    77701 gtaacaacta gtactttttt aatatctttc gtttttcttg tcagcaattc atcaaatttc
    77761 tgatactttt ttggcgataa aataagctgg acaaaggcta cgccatagta acggacaagc
    77821 aaaaatccga ttgcttcccc aatcactagg ccaatacaac tatataaaag cccaaatcca
    77881 ttgccaaaca tcagcatgcc cgctactgag gagatccctc ccggcaaaat aggaatgatc
    77941 acttggatca cttgcaacag aacaaatatc atcactgcat acttgccaaa ttgctggata
    78001 aacgcttgca aagacgtgct cgatcgaaaa atcccatgat gataagcata aagaatcaac
    78061 acaaagaaaa aaaacagacc aataatgggc atgatctgaa gacatttttg taaaactgat
    78121 ccttttttag acatctatat tccccacatc ttttttcatt tattaaaact gcctcctt
//
LOCUS       DAPBAF010000007        71881 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.007, whole genome shotgun sequence.
ACCESSION   DAPBAF010000007 DAPBAF010000000
VERSION     DAPBAF010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 71881)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 71881)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..71881
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.007"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            11..589
                     /locus_tag="RD451_000565"
     CDS             11..589
                     /locus_tag="RD451_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565855.1"
                     /translation="MNILFLLLFFLIFLLTYRKCQNYYVRILTALPFFLNLIIYFGNT
                     MGQSFTYVNGNKRAMIWSSSNLNNLFTELGTKLSLFYPGTWIATLVVLALLLCLIVGI
                     YLSFDNKKTSIFLVILMIMGFCSRLIMGFSPTVWASGMRTYYILYVVIAILVLMAVKE
                     LMKSMSVQKNEFMQFGLTVLGICTFIITVINR"
     gene            complement(829..912)
                     /locus_tag="RD451_000566"
     tRNA            complement(829..912)
                     /locus_tag="RD451_000566"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(876..878),aa:Leu,seq:gag)
     gene            967..1146
                     /locus_tag="RD451_000567"
     CDS             967..1146
                     /locus_tag="RD451_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565856.1"
                     /translation="MGGLIKMEKYDGEFSGLGMILGVLIGLAFGRFLLGFMLGIICGI
                     AMDWAANLWNDYHDN"
     gene            1295..2512
                     /locus_tag="RD451_000568"
     CDS             1295..2512
                     /locus_tag="RD451_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDT7565857.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            2696..3532
                     /locus_tag="RD451_000569"
     CDS             2696..3532
                     /locus_tag="RD451_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7565858.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            3608..4756
                     /gene="nagA"
                     /locus_tag="RD451_000570"
     CDS             3608..4756
                     /gene="nagA"
                     /locus_tag="RD451_000570"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HDT7565859.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            4977..6035
                     /locus_tag="RD451_000571"
     CDS             4977..6035
                     /locus_tag="RD451_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HDT7565860.1"
                     /translation="MNLFDIFRSTLTDMSIVSAITSTVFIILLGFVCRKKGIFSESVG
                     KILSKVVLTVALPALAFRAFMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYK
                     GDKQTTLRVLTIFGSTTFFGTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGL
                     KMEAKNIKAMFVNPIIIATFAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPW
                     LFQPMDYLAGLSSPLAWLAIGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILA
                     VLTATNILPVNFEALATIVIMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVL
                     TPVWIVVLQMIHGIGLFS"
     gene            6039..7073
                     /locus_tag="RD451_000572"
     CDS             6039..7073
                     /locus_tag="RD451_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate dehydrogenase"
                     /protein_id="HDT7565861.1"
                     /translation="MEEESMRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIV
                     SAKDHDAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVP
                     SYSPNAIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRI
                     GLTEAVLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQ
                     MINEGFLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSF
                     KPWETIPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNE
                     VSLPKARQLR"
     gene            complement(7175..7891)
                     /locus_tag="RD451_000573"
     CDS             complement(7175..7891)
                     /locus_tag="RD451_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HDT7565862.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(7860..8645)
                     /locus_tag="RD451_000574"
     CDS             complement(7860..8645)
                     /locus_tag="RD451_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spo0B domain-containing protein"
                     /protein_id="HDT7565863.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            complement(8636..9385)
                     /locus_tag="RD451_000575"
     CDS             complement(8636..9385)
                     /locus_tag="RD451_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HDT7565864.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            9683..10207
                     /locus_tag="RD451_000576"
     CDS             9683..10207
                     /locus_tag="RD451_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HDT7565865.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            10223..11722
                     /locus_tag="RD451_000577"
     CDS             10223..11722
                     /locus_tag="RD451_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HDT7565866.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(11810..12412)
                     /locus_tag="RD451_000578"
     CDS             complement(11810..12412)
                     /locus_tag="RD451_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HDT7565867.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            12516..13472
                     /locus_tag="RD451_000579"
     CDS             12516..13472
                     /locus_tag="RD451_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HDT7565868.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            complement(13777..14733)
                     /locus_tag="RD451_000580"
     CDS             complement(13777..14733)
                     /locus_tag="RD451_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDT7565869.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            14907..15467
                     /locus_tag="RD451_000581"
     CDS             14907..15467
                     /locus_tag="RD451_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565870.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            15460..16284
                     /locus_tag="RD451_000582"
     CDS             15460..16284
                     /locus_tag="RD451_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HDT7565871.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            16294..16911
                     /locus_tag="RD451_000583"
     CDS             16294..16911
                     /locus_tag="RD451_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HDT7565872.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            16929..17612
                     /locus_tag="RD451_000584"
     CDS             16929..17612
                     /locus_tag="RD451_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HDT7565873.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            18295..19578
                     /locus_tag="RD451_000585"
     CDS             18295..19578
                     /locus_tag="RD451_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HDT7565874.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            19594..20481
                     /locus_tag="RD451_000586"
     CDS             19594..20481
                     /locus_tag="RD451_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDT7565875.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            20498..21334
                     /locus_tag="RD451_000587"
     CDS             20498..21334
                     /locus_tag="RD451_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDT7565876.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            21337..21960
                     /locus_tag="RD451_000588"
     CDS             21337..21960
                     /locus_tag="RD451_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565877.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            21957..23249
                     /locus_tag="RD451_000589"
     CDS             21957..23249
                     /locus_tag="RD451_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDT7565878.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     regulatory      23608..23705
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            23821..24402
                     /locus_tag="RD451_000590"
     CDS             23821..24402
                     /locus_tag="RD451_000590"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HDT7565879.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     gene            24405..25712
                     /locus_tag="RD451_000591"
     CDS             24405..25712
                     /locus_tag="RD451_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HDT7565880.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            26128..26616
                     /gene="purE"
                     /locus_tag="RD451_000592"
     CDS             26128..26616
                     /gene="purE"
                     /locus_tag="RD451_000592"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HDT7565881.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            26609..27733
                     /gene="purK"
                     /locus_tag="RD451_000593"
     CDS             26609..27733
                     /gene="purK"
                     /locus_tag="RD451_000593"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HDT7565882.1"
                     /translation="MVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVSDCP
                     AAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTDLLA
                     ITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKGQYV
                     LKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHNNIL
                     HETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRPHNS
                     GHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENKPDW
                     QFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            27746..29041
                     /gene="purB"
                     /locus_tag="RD451_000594"
     CDS             27746..29041
                     /gene="purB"
                     /locus_tag="RD451_000594"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HDT7565883.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(29221..29598)
                     /locus_tag="RD451_000595"
     CDS             complement(29221..29598)
                     /locus_tag="RD451_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565884.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            29854..30582
                     /locus_tag="RD451_000596"
     CDS             29854..30582
                     /locus_tag="RD451_000596"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HDT7565885.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            30582..30836
                     /gene="purS"
                     /locus_tag="RD451_000597"
     CDS             30582..30836
                     /gene="purS"
                     /locus_tag="RD451_000597"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HDT7565886.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            30838..31509
                     /gene="purQ"
                     /locus_tag="RD451_000598"
     CDS             30838..31509
                     /gene="purQ"
                     /locus_tag="RD451_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HDT7565887.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            31510..33732
                     /gene="purL"
                     /locus_tag="RD451_000599"
     CDS             31510..33732
                     /gene="purL"
                     /locus_tag="RD451_000599"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HDT7565888.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            33717..35156
                     /locus_tag="RD451_000600"
     CDS             33717..35156
                     /locus_tag="RD451_000600"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HDT7565889.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            35179..36231
                     /locus_tag="RD451_000601"
     CDS             35179..36231
                     /locus_tag="RD451_000601"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HDT7565890.1"
                     /translation="MNSMANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGF
                     GGCFDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEP
                     LYFLDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFA
                     VGIAEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKK
                     TLGEELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSW
                     PILPIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVEESKVKEIVHEIEQAGEKVYEIGK
                     VIAKEKHRVVFIGEER"
     gene            36228..36806
                     /gene="purN"
                     /locus_tag="RD451_000602"
     CDS             36228..36806
                     /gene="purN"
                     /locus_tag="RD451_000602"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HDT7565891.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            36803..38338
                     /gene="purH"
                     /locus_tag="RD451_000603"
     CDS             36803..38338
                     /gene="purH"
                     /locus_tag="RD451_000603"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HDT7565892.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALVFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            38354..39628
                     /gene="purD"
                     /locus_tag="RD451_000604"
     CDS             38354..39628
                     /gene="purD"
                     /locus_tag="RD451_000604"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HDT7565893.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            39750..40664
                     /locus_tag="RD451_000605"
     CDS             39750..40664
                     /locus_tag="RD451_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HDT7565894.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(40797..42362)
                     /locus_tag="RD451_000606"
     CDS             complement(40797..42362)
                     /locus_tag="RD451_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HDT7565895.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(42355..43806)
                     /locus_tag="RD451_000607"
     CDS             complement(42355..43806)
                     /locus_tag="RD451_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDT7565896.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIRESKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(43820..44836)
                     /locus_tag="RD451_000608"
     CDS             complement(43820..44836)
                     /locus_tag="RD451_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDT7565897.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            45056..46144
                     /locus_tag="RD451_000609"
     CDS             45056..46144
                     /locus_tag="RD451_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding protein"
                     /protein_id="HDT7565898.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            46198..47724
                     /locus_tag="RD451_000610"
     CDS             46198..47724
                     /locus_tag="RD451_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HDT7565899.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            47726..48931
                     /locus_tag="RD451_000611"
     CDS             47726..48931
                     /locus_tag="RD451_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDT7565900.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            49188..50165
                     /gene="guaC"
                     /locus_tag="RD451_000612"
     CDS             49188..50165
                     /gene="guaC"
                     /locus_tag="RD451_000612"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HDT7565901.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
     gene            50429..51853
                     /locus_tag="RD451_000613"
     CDS             50429..51853
                     /locus_tag="RD451_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDT7565902.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            52314..53423
                     /gene="pdhA"
                     /locus_tag="RD451_000614"
     CDS             52314..53423
                     /gene="pdhA"
                     /locus_tag="RD451_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HDT7565903.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            53426..54403
                     /locus_tag="RD451_000615"
     CDS             53426..54403
                     /locus_tag="RD451_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HDT7565904.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
     gene            54428..56071
                     /locus_tag="RD451_000616"
     CDS             54428..56071
                     /locus_tag="RD451_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HDT7565905.1"
                     /translation="MAYQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHEDNEGDSGVAAESQTPAKPAA
                     EPTVDTESAGSSSEGVFQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSAEAPKEKVETS
                     GSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKEDIENFLAGGPS
                     SAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPTRKAIAKAMVN
                     SKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALTATVKKYPVLN
                     ASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEINEKAKLAHDG
                     KLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIVNAEGEIVVGR
                     VMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            56079..57485
                     /gene="lpdA"
                     /locus_tag="RD451_000617"
     CDS             56079..57485
                     /gene="lpdA"
                     /locus_tag="RD451_000617"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HDT7565906.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            57647..57922
                     /locus_tag="RD451_000618"
     CDS             57647..57922
                     /locus_tag="RD451_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HDT7565907.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            57928..58695
                     /locus_tag="RD451_000619"
     CDS             57928..58695
                     /locus_tag="RD451_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HDT7565908.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            58863..60692
                     /gene="typA"
                     /locus_tag="RD451_000620"
     CDS             58863..60692
                     /gene="typA"
                     /locus_tag="RD451_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HDT7565909.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            60953..62725
                     /gene="recQ"
                     /locus_tag="RD451_000621"
     CDS             60953..62725
                     /gene="recQ"
                     /locus_tag="RD451_000621"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HDT7565910.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            62839..63141
                     /locus_tag="RD451_000622"
     CDS             62839..63141
                     /locus_tag="RD451_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HDT7565911.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            63144..64307
                     /locus_tag="RD451_000623"
     CDS             63144..64307
                     /locus_tag="RD451_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HDT7565912.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            64333..67761
                     /locus_tag="RD451_000624"
     CDS             64333..67761
                     /locus_tag="RD451_000624"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HDT7565913.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            67782..68906
                     /locus_tag="RD451_000625"
     CDS             67782..68906
                     /locus_tag="RD451_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565914.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            68896..69333
                     /locus_tag="RD451_000626"
     CDS             68896..69333
                     /locus_tag="RD451_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HDT7565915.1"
                     /translation="MIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESAKVC
                     QLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQLQS
                     LLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            69317..69655
                     /locus_tag="RD451_000627"
     CDS             69317..69655
                     /locus_tag="RD451_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HDT7565916.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            69774..70334
                     /gene="rsmD"
                     /locus_tag="RD451_000628"
     CDS             69774..70334
                     /gene="rsmD"
                     /locus_tag="RD451_000628"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HDT7565917.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            70331..70822
                     /gene="coaD"
                     /locus_tag="RD451_000629"
     CDS             70331..70822
                     /gene="coaD"
                     /locus_tag="RD451_000629"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HDT7565918.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            70812..71855
                     /locus_tag="RD451_000630"
     CDS             70812..71855
                     /locus_tag="RD451_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HDT7565919.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
BASE COUNT        23317 a        12333 c        15785 g        20446 t
ORIGIN      
        1 ttttttagac atgaatatct tatttttatt gctatttttc ttaattttcc ttctaacata
       61 taggaaatgt caaaactatt atgtgcgtat attgactgca ttaccgtttt tcttaaacct
      121 gattatttat tttggtaata caatgggtca aagctttact tacgtcaatg gaaataaaag
      181 ggcaatgatt tggagtagta gtaacctgaa taatctcttt acagagttag gaacgaaact
      241 gtcacttttt tatccaggta cttggatagc tactttagta gtcttggcat tattactatg
      301 tttaattgtt ggaatttatt taagttttga caataagaaa acttctattt ttttagttat
      361 tttgatgata atgggatttt gttcaaggtt aattatggga ttttctccca cagtatgggc
      421 ttccggaatg cggacgtact atatacttta tgttgttatc gccatcttag tactaatggc
      481 agttaaagag ctaatgaaaa gcatgagtgt acaaaaaaat gaatttatgc aatttggatt
      541 aaccgtgctt ggtatttgta cctttataat aacggtgata aacagataat atacaaaaaa
      601 tccctcgctt tagtattagg tgagggattt tactcgtttt tcgattaatt gttttaacac
      661 ttgcaagttt ctacgagtag cttgtttccg accttcatat actcacctca ggctgtttac
      721 atgattgtac gttctttttg taaaggatac agtgatatgt atataatggc ataaagaaac
      781 gttcaaacaa aaaaactcgt gaagcaaaat taacttcacg agttgtagtg cagatgatgg
      841 gactcgaacc cacacgagct aacgctcaca tgaccctcaa tcatgcttgt ctgccaattc
      901 caacacatct gcgtaataat aacacactaa tgatagcgag gttttacata gttgtcaagc
      961 tcaaaaatgg gaggacttat taagatggag aaatatgacg gagaattttc aggactggga
     1021 atgatcttag gtgtattgat tggacttgca ttcggacgtt ttttgcttgg ttttatgcta
     1081 ggaatcattt gtggaattgc aatggattgg gcagcgaatc tatggaatga ctatcatgac
     1141 aattaagttc tcaacgcttg tttgtgtttt tttaatactt acgtttttcc taaataagtg
     1201 gcaaaatttt ctaggatgga gtatgatatt gaaatagtaa ataacaaaaa atttggaaag
     1261 ttctaacttt ttgaaatgag ggattggcta agtgatgaga gaatttgaaa aatccaacaa
     1321 attagaaggt gtcagttacg atgttcgcgg tcccgttcta gaagaagcgg agcggatgca
     1381 agaagagggc attagtattt taaaattgaa cacgggaaat cccgcacctt ttggatttga
     1441 agcaccaaac gaagtcattc gtgatttgat catgaatgcc cgtgactcag aaggctactc
     1501 agattccaag gggatctttt ctgctagaaa agcaattgag caatattgcc aactgaaaca
     1561 ttttccgaat gtgacgatca atgatatcta caccggcaac ggagtgagcg aattgatcac
     1621 gatgtgtatg caggggttgc tggacaatgg agatgaagta ctggttccaa tgccggacta
     1681 tccgttgtgg acggcttcta ttgcattagc tggaggcaca cctgttcatt atatttgcga
     1741 tgaagaggca gaatggtatc ctgatattga tgatatcaaa tcaaaaataa cgagtcggac
     1801 aaaagctatt gttatcatta atcctaataa tcctactggg gcactttatc caaaagaatt
     1861 attagaagaa atcgttgaag tagctcgaca aaataacctg attatttatt ccgacgaaat
     1921 ctatgatcgc ttagtgatgg atggtctaga acatattccg attgctacat tagcgcctga
     1981 tttgttcgtt gttacgctga acggtctatc caaatctcat cgtgtagcag gatttcgagt
     2041 aggctggatg gtcctaagtg gagataagtc acacgtcaaa ggctatatag aagggctgaa
     2101 tatgttgtcc tccatgcgtt tgtgttccaa tgtattgtct cagcaaatta tccaaaccgc
     2161 gctaggcggt tatcaaagtg tcgatgagct gctcctgcca ggcggaagga tctatgaaca
     2221 aagagaatat atctataatg caatcaatga tattcctggt ctttcagccg taaaaccaaa
     2281 agctgctttt tatatattcc caaaaattga tacaaagcga ttcaatattt tggatgatga
     2341 aaaattcgtt ttggactttt tacatgaaca tcatattcta cttgtacatg gtggtggatt
     2401 taattggaac cagccagatc attttcgaat cgtttatctt cctaaaatgg atgatttgaa
     2461 acaaacagct aagaaaatga gagaattcct agcaacctat cgccaaaaat gattttaaaa
     2521 accaaatttt tcagtaggag ggccacagac aaacacactg aggctctctt tctagtggag
     2581 ttttcttaaa taactaaagt atattattta gttgcaagtc ttttcttgaa gtttgcgact
     2641 tcctaaagta aaatacgaat agaatgcgaa tacgcatatt ttggggagga tacttatgga
     2701 aacgttaatc gagtcctttg gaacgatcat taaagagatt cgaaaagaac aaaaaatgac
     2761 gcaaaaaatg ctttcgcatg atatttgttc acaaagtgta ttaagtcgga tcgaaaataa
     2821 tgaggaactg ccgaatgtat tggtgatgat gcagatttgt caacggctag gggtaacgat
     2881 tgatcatgtg atgaatctct ctcgaaaaac tactcggaca aacgataaat tatttgaact
     2941 gttggatagt tgtttccaaa aacgtgatta tcggaagtta gaacaagtac taaaatcttc
     3001 tgatatttct gaaaatctgt atcaagcaac tgactttcaa cgctattatt attatctcgg
     3061 tgtttgcgaa ttcacgttgc gtcaaaatat ctctcagtcc ctttattatt tgaaagaagc
     3121 attaagctac tctagccaaa aagaaagaat ccatgtttct gacacagaaa tacaactgat
     3181 tagttgtatc ggaaaaatat atggtgtggc aggaaaaacg gctgaagcac gctactattt
     3241 gagtcgaagc atccaactgc tgcatcaatc agctgatgaa cgatcaaaaa gtgaattttc
     3301 gcaaattttt tataattatg gaaatttctt attccatcaa aatgaaatcg acgaagcgtt
     3361 agaacaggtg aatcaaggaa tctattgggc tcaagagaag aatagctact attacctcaa
     3421 tgatttattt gtgcttaaaa gcttaatata caagcgtaaa gaagaaccag aaagagcagc
     3481 attctatgaa ggcttagcac aagctgtgaa acaaatttca aaaaatttgt aaatggtgta
     3541 gaccattctt gacttcttct ctaaataaga gtactttaga ggtagaaaaa caaagggaga
     3601 gaatagaatg agaactttta tctatgctga caaattcttt ttagcgtcag gtgtcaaaca
     3661 tgcaggctat cttgaaatta ccgatggact ttttggtgaa tacaccaaag aactacctga
     3721 gggagaagtc aacatcattg accaaagcgg caaatggatt gctcctggtt tggtagatac
     3781 acatattcac ggctatatga atcatgatgt aatggataat gatgcagaag gcatcaaagt
     3841 gatgtctgaa ggtctgttat cttgtggagt gacttcattt ttaccaacaa cattgacgtc
     3901 aagcaaagaa cgtttaaaag atgtagctga gacaatcggc aaaatgtatc aggaagcacc
     3961 aggagctaaa atcaaaggaa tctattttga aggtcctttc ttcacagaag aacacaaagg
     4021 ggcacaaaac ccaagttatt tcggggatcc tgatttggat actttccatg aatggcaaga
     4081 agcttcaggt ggtttaatca aaaaaattgc tttagcaccg gaacgtcaag gtgtagaaga
     4141 gtttgtcaaa caagtgactg aagaaggagt agttgtttct ctaggacaca gtaatgctac
     4201 actagaagaa gcgcaaaaag ctgttgaagc aggcgcaagt gtatttgtcc atgctttcaa
     4261 tggtatgcgt ggattgaatc atcgcgaacc aggtatggtg ggtgcgttat tatctttaga
     4321 acatgtcttt tctgaattga tttgtgatgg ccatcatgta catccaaatg ctgcgggaat
     4381 cctaatggaa aaagcaggac atgatcatgt cgcattaatt acagactgta tgatggccgg
     4441 tgggatgcct gatggaaatt acaatttagg cgaatttcca gtagtagtaa aagaaggaac
     4501 agcacgtcta gaatctggca acttagctgg aagtatattg aaattgaaag aagcaattaa
     4561 aaatgttgta gactggggat tagcaacacc agaacaagca gtcatgatgg ctagtctgat
     4621 tccagcaatc agctgtaaaa tcgatgatac atgtggaaaa atcgctcaag gacgcgatgc
     4681 agactttatc gtattgaacc ctgatatgac attggaagca acttatctag atggcgtgga
     4741 acgtttccac gcataatata atttaagtta accttaaaac taaacttctt aagtttggtt
     4801 ttaaggtttt ttttgtgttc tagtaaaaat cactttacat aagtttcaaa agtttcttta
     4861 atttcctatt gttcaataag taacaatgta aagataaaat taaaaatgtt aatacgtatt
     4921 agcaaaataa aagctttttt tattgtgaat aaatgaacat aattaggagg agaaagatga
     4981 acttatttga catttttcga tcgactttga cagatatgtc gattgtcagt gcaatcactt
     5041 caacagtttt tattatatta ttagggtttg tttgtagaaa aaaggggatt ttttctgaat
     5101 ctgttggaaa aattctatcg aaagtcgtct taacagtggc tttgccagca ctggcatttc
     5161 gagctttcat gcaagatatc aatacagaat tactgatgca aggaatcaat gtcttgattt
     5221 ggggattagt tatttatatt attcttattc tagtttcaaa accttttttc ttaagctata
     5281 aaggggataa gcaaacaacg ttgcgtgtcc tgacgatctt tggttctacg acctttttcg
     5341 gaacgcctat cgtcagtgcg atttatggtc ctgtcggcgt gatgtattcc tcaattttca
     5401 atattggcta ccgaatcttt ttgtattctt atggatacat aaaaatgagt ggcttgaaga
     5461 tggaagctaa aaatatcaaa gcgatgttcg tcaatccaat cattatcgct acttttgccg
     5521 gccttttcat ttggctgttc caagggtatc tgccacaagt gtcagttaca ggtgcagaag
     5581 gagagataag ccaagtagcg tttttgcgaa ttgaccagac tgcaccgtgg ctatttcagc
     5641 cgatggatta tttagctggt ttaagttcac cattggcgtg gctagcaatc ggcgcaacat
     5701 taggtgaagt aagcttcaaa aaagctgcat ctgaaaaaac ttcatggtat tacagtctag
     5761 tcaaagtggt atttgtacct gcattgaata tcgtgattct agcagttttg acggcaacga
     5821 atattctacc agtcaatttt gaagcactgg caacaatcgt tatcatgatg gctacaccag
     5881 ctgcaacagt ggcagcagcc tatgctatca gttttgatag ggaggcactt ttagcctcca
     5941 atgcatcctt actgtcaact atttttgctg tggtactgac acctgtatgg atcgttgtat
     6001 tacaaatgat tcatggcata ggtttatttt cataagaaat ggaggaagaa agtatgagaa
     6061 tcgcatgtta cggtgttcgt ccgaacgaga tagatttttt tgaaaaattg aatatttacc
     6121 attatgatct cagtctttat gaagaactgt tgacacatga caatatcgtg tcagcaaagg
     6181 accatgatgc tgtattgttg aggggaaatt gtatagcaga tgagaccaat cttgcaaaaa
     6241 tgcaggaata tgggattcgt tatgttttta cacggactgt gggagtcaat catatcgatc
     6301 tacaagcggc agctgatttt ggtatgacag tagcccgtgt accatcgtat tcgccaaatg
     6361 cgatagcaga gttatctttg acttttgcca tgatgctttt gagaaatact gcgtatacga
     6421 cgatccgaac atctttcaaa gattttcgag tggatgagca aatgtttagt cgtgaaatca
     6481 gaaattgcac agtagggatc ataggaacag gcaggatagg gttgacggaa gctgttttgt
     6541 ttaagggact aggagccaaa gtgatcggct acgatattca tcagacagaa gctgctaaaa
     6601 aagtattgac gttccactcg cttgaagagt tattagccaa aagcgatatt gtcagtattc
     6661 atgtacctca tatcccaggt gaaaacgatc aaatgatcaa tgaaggattt ttagctcaaa
     6721 tgaaaaaagg tagcatcttg attaatacag cccgtggaga gcttcaagat aatgaagcta
     6781 ttttaagagc tttgaaaagc aatcatttag ctggttttgc aaccgatgtt tttgcaaatg
     6841 aaacagaggt ttttttccga tccttcaagc catgggagac gattccagac cctgctatcc
     6901 agcaattagt agaaatgtac cctagagttc ttgtaacccc gcatgtaggt tcaaatacag
     6961 atgaggcatt atcaaatatg atttcgacaa gtttcgagaa ctttcgtgaa ataatagaaa
     7021 ctggaaaaac gaaaaatgag gtatctcttc ctaaagcccg tcaattaaga taagaaaaca
     7081 tggatattcg tcaataaaat gtttaaaaat agtccaagta aacagttgtt acttctgtat
     7141 acttggacta ttttgtatgg gataattcga tgactcaaca gtaatctgtg agctttttcc
     7201 gcccattctt tgtcaattca taacaggtta gcggccggcc gatttccaaa tatttgattc
     7261 tttcgttcaa tatatcttgt tctactaaaa aattcaaata tttcttgacg gatatacgtg
     7321 acagtgagct tttttgagcc agttcttttg ttgaaaaaat agtatcttct tttagaataa
     7381 atgcacttat tttttttaaa gtcagttttg acagaccttt aggcaaatcg atgaatgatg
     7441 gtatttcgtg aatgggagtg gtgtggttga atacttgatc gatcaatttc tgatcggctt
     7501 tttcagtcgt ttggattgtc tgagagaaag caagatactt ttcgatcgcc agctgaaaac
     7561 gttgcaaagt gaacggtttg atcaaataat ctaaggcacc gtagcggatc acattcttta
     7621 tggtttcgat atcatctgca gcagtgatca aaatcactgg gatatcattt ccttgctgtc
     7681 taagccaaga taaaaaatgg ataccacttt cgccaggcat gtatacatca agcagcagca
     7741 gatctgcgtt tttttgtctg aaatattttt ttccttcttc tacatttctg aaactttcga
     7801 ttacgttcat attagggatg ctttccacaa aagtacgatt caattctgca accattggat
     7861 catcttcgat tatcaggaca tttgtcatca ttttgatctt ccttttttgg taattctaga
     7921 tagacgattg taccgccatt tgtttgtttg gaaaattcta aaaatccacc gtggcgtttg
     7981 acgattgaat ggatgagatt caatccaaac ccacgattga ttcccttcgt cgaaaaacct
     8041 agcgtaaata ttttttctga gatttcttct gatatcccga caccgtcatc gcagacggtc
     8101 acgatgaata cttcagcttc tgtgtcatag tttaaatgaa tccggacctg tccgtttctt
     8161 tcatgttttt gtagcacggc ttcttttgca ttatcaagta agttccctaa cacttgcaaa
     8221 agtgaatgga tggagtcatc catctccatt ttagggataa aagaatcgct ttctaacagc
     8281 atttcaacag attgttcttt ggcttcgttt attttgccta ataaaaaacc ggcaattgca
     8341 ggtactttga tcagacttga gacttggcca atctcttttt tataattttg atttagctgc
     8401 tggataaaat gggtgacttc ttcatacttc ttcaaatcaa tcaaaccaga aatgacatga
     8461 agtttattca tgaattcatg ggtttgagct ctcatggagt ttatatattg tttcgtcccc
     8521 ccaagctcct ccattaattt cattacttct gatcgatttc gtaaagttgc gactgctcct
     8581 aaaaaacggt cattgctaaa aagaggtgta acgctagaaa tagtttctat cccatttaaa
     8641 tacatggatt gagtccgaac ggtcgtttga tgctcaatcg tctctttaaa caaaacgtca
     8701 tatagattat cactgatttt tttcctactt cgaaatccaa tagctgctct gtttggtaga
     8761 aaatgttttt tgcaggtgta ttgatcaaga ggatagtttt atcagaagag atggctaaga
     8821 ttccttcatc tacttcattt tcgataatcg ttttttcact taactgttct gctatttctt
     8881 gtggttcaag tccaagcagt acttttttca ttttttgggc aagaaaaacg gcgcctatga
     8941 tgcctacgct aagtccaata atcaatgaaa aaacaatcat tttttgtcca tctttgactt
     9001 gattgtcaat cgtgttgttt gttaagccaa cacaaactgc accaataatc tcttgatcat
     9061 aataaatagg gacgaaatag cggaagccga accctaacat tccttctttt tcagagaaaa
     9121 attcttgtcc tccaatcact tttttcacat cttcatgact tgagaaagga agaccgatgt
     9181 aacttgggtc tgcgtgagaa tatcgaatgc cttcagggtc catgacaacg ataaaatcta
     9241 aattcgatgc aatcatgatt tcatttgtta ttccttgaat cgcatgtgtc gggtcaccag
     9301 tctgcagctt tttttggatg agtttatcat tggcaacgat tttagcaatg ctagagattt
     9361 tatctgacac actagatcgg ttcatcgaaa gaataaaatt cctgatcaat atggcagaaa
     9421 caatcaaaga aacgaatgtg gagaaacaaa cgacaaggat gatcgtgttc tggagcttta
     9481 atggtttttt cttaaaaaaa ggaaacatag gctacctcga aagaatttat tgtgaaaatt
     9541 ttaacatgaa aacaaaaatt taacaaattg tcaacgataa acacaacctt cctataaaaa
     9601 acaccactga gtcggtaaaa gaagctatac agaattttca aacattggta tgatagacgt
     9661 agaaatggaa ggaggcgtgt atatgatagg gggaatcgca cttgagacga tttattggta
     9721 tacattgctg atttgtgcag gattggcagt cctattgatt atttttggag atgtattcga
     9781 ttttgatggc ccgcttgatc cgatgcttat tatcccttgg ttaactttca caagcttatt
     9841 tggttttcta ggtgagcgtt taacagatca atcatcttta tttttattta ttgctagtgg
     9901 aggcatatcg atagtgttgg tatttttgct taatttctat atattgatgc cgatgaaaca
     9961 tgccgaatca acgatgtcgt cttctgaaaa aactctggaa ggacaagtag ctgttgtgat
    10021 cacaccgatc cctgtacgag gtatgggaga aattcagttg aaaagtgtta ccggttccat
    10081 tagtcgtcca gcttgttttt acagccccca agaacagaca gctgagcggg gaacgaaagt
    10141 attgatcatt gagatcaagg aaagaatctg ttatgtcatg ccttatgaaa gcatgataaa
    10201 agcttaaagg agcgtgtgtt aaatggaaat accagttgtt tttatcgcga tcgcaatcgc
    10261 agctttgatt ttactgatgt tgctgatcgt ctttgtagcg aagtaccaga cagcaaaacc
    10321 ggatgaagcg ttgatcatca gtggaagtta tttaggaagc aaaaatgtgc acattgatga
    10381 aagcaataac aaaatcaaaa ttgtgcgtgg aggtggcgca ttcgtcttgc cagtttttca
    10441 acgttcgaat cggatcagtc tattatcgag taaattggac gtctccaccc ctgaagtgta
    10501 tacggaacaa ggcgtaccgg tgatgtgtga tggtacttcg atcatcaaaa tcggttcatc
    10561 tgtagaagag attgctacag cagcagaaca gtttttaggc aagacaagag aagaactgga
    10621 aaatgaagca agagaagtat tagaaggaca cttgcgctcg attcttggtt ctatgactgt
    10681 agaagaaatc tatcaaaatc gcgataagtt cagtcaaagc gtacaagaag tcgcttctgt
    10741 agaccttgca aaaatggggt tgatcatcgt ttctttcact atcaaagagg tcagagacaa
    10801 aaacggttat cttgactctt tagggaaacc aagaatcgcc caagtcaaaa gagatgcaga
    10861 tatagcagaa gcggaagctc taaaagaaac gcgtatcaaa aaagctcaag cagaaaaaga
    10921 atcacaagca gctgaattac agcgacaaac agagatcgca gaatcattaa aagaaaaaga
    10981 actgaaatta gcaacctaca aacaagaaca agatgttgct aaagcaaaag cagaccaagc
    11041 ctacaattta gaaagtgccc gagcacaaca acaagtaatc gaacaggaaa tgcagattaa
    11101 aatcgtagaa cgtcaaaaac aaatcgaact ggaagaaaaa gaaatcacac gtcgtgaaaa
    11161 gcaatatgat tcggaagtga agaaaaaagc agatgccgat cggtacgcta aagaacaaga
    11221 agcacaagct caaaaagtca aagaagtgac tgaagccgaa gcagaacgat tccgtgtgga
    11281 agcactggca gaagcggaag ccaataagac acgtttagct ggacaagcag aagccgaagc
    11341 agcactagca aaaggaaaag cagaagccga agcaaaacaa aagatcgcca atgccttcaa
    11401 ggaatatggc gaagcagctg tcttgagtat ggttatcgat atgctaccgc aattgatgcg
    11461 cgaagcagca cagccgctag gaaatatcga aaaaatctct gttgtcgata caggaagcag
    11521 ttcaggagaa accagtggag cgaaccgagt gacaaattat gccacaaatt tgctttcttc
    11581 tactcaagaa acactaaaag cgacaacagg acttgacttg aaggaaatcg tagagaattt
    11641 gtcgacacgt gggactacta gccaagtaaa tatgtatgaa gcgccaaaag aggcagaaca
    11701 aaactcgatg aaggaagaat aaagtagtac acttcaccgt tcaatcaaaa atggaggaag
    11761 actttttaaa gttcttctct ccattttttt attttattgc aaaagaaaat tagtcctcgc
    11821 tatttttctt ttgtttttgg atcttagctt ctatctcttg taaatttgtt cttagcaatc
    11881 gttctttctt ttggagttcg accaaatctt ctgatagttc ttccttcttt tctgtttcag
    11941 gaggacgaag aaagaaattg ataccgattg caatgaatgt ccctataaaa gtatctagta
    12001 cacgttggat agcatacaaa gcggattcgc cttgagggat gctcaacgca atcagcaaca
    12061 acgtagctat tgcggaaatg ataccggaat tattgttaat accatctgac acgacgatca
    12121 caataataac tagaatagga agcaagatca attctaccaa aaaatcattg tgaaaatagc
    12181 ttttgacaaa aaaataaatg atagctaatg taccacctaa tgtattgccg atgatcctag
    12241 actttccaaa agaaacggtt gtagtcaagt cctgacgcaa agaaaaaaca gcagataatg
    12301 cagcaatcat cgggattcct cgttgagtca aatgaaaaaa caagatacat aaaaaaacag
    12361 ctaaggcact tttgatcgta cgcataccta gtcgaaaacg gccaaattgc atagagattc
    12421 tcctttttgg tctttttact atcataccta aacttttgtc tgatagctag tttttcatta
    12481 ttcaagtata attaaaataa aaaaggggga agtaaatgcg tataggaatg cgaacagtca
    12541 aaacagtgat cagtgtcttc ttttcgatgg tcacagcggg tagcttatcg ctgttgtatt
    12601 ggccagctgc agggatcatt gcattattaa gtgtaggaaa taccaagcgc tctacattgc
    12661 gtacgggcat gaatcgaatc gcagccttta tattagctac ggcaacagca ctgttcagtt
    12721 tttttgctgt tgggtatact atttttggct tcagtctttt tttattcctg ttcatcccgc
    12781 ttgcctctcg cttcaaatta accgaaggga tagtagtaaa ttcggttttg gtcactcatt
    12841 atttagtgga ggaaaacatg tcttggcagc tgatcggcaa tgaagcggga ttaatggcga
    12901 ttggattagt atttgctttg cttgcaaatg tttacatgcc agatcgtacg aagcagctga
    12961 aggaaaacca aatacagatc gaaaaagaat ttcgaaatat tttgagacaa atggcagaat
    13021 ttcttttatc agaaaataaa gaagatgtgc agatcaaatg cgaacattta ctgacattca
    13081 ttcgcgaaag ccaagaagat gccagagaac atcaagaaaa ctactggctc agacagccgc
    13141 tatactacga aacttacttc tctatgagaa gagcacaggc caatgtgatt aaagacatgc
    13201 tggaaaatct agagagaatc cagcaaccag cttattatgg aaaacatatc tatggtttat
    13261 tgatttatac tgcagaaaca ttttcagagt caaatgatgg cagacaaatt ttaacacgta
    13321 ttgaagaagt ttatgtattg tatcggcaaa tgcctctgcc gactagtcgc cctgaattcg
    13381 aggatcgagc agaattgttc cagtttttgc agtcttttaa aagttttatt gaaatcaagg
    13441 cagaattctc ccaacaaaaa atccaaaaat agaggttgtg aattcagcta atattcaggt
    13501 caaaaagctg atttcacaac ctcttcttta aacggtgttc tcctgtcaac tcctcggtca
    13561 caagtcacaa tattcaacaa acatgagaag ctgttttttg aaattgctcc ttgtgactcg
    13621 gagctgaacg gtaggctcac aacctctttc ttaaacggtg ttcaaaagct ttcctctgcg
    13681 gtaataagtc cagccaaacg aaaaatagga ggagctattt ttgtttggct gttcttatta
    13741 cttgatgcag aacagctttt tcacaacctt ttaaaattac atatttttcc atagaacttg
    13801 catttgatcc aagatttcga tgacatcttt tgtcaagaag agagagcgat tgggcaagtc
    13861 accttcaatc atgtgtacca tattctttat ttcgtaattc attgcttcag atgtattccc
    13921 gctttcgatg aattcctttg taccatctgt aaataagatc tccgcacgat cagcacgcgg
    13981 gtaatcagca atcgtcacat aaccgttctc aaaggcaacg ataccgactt ttggcatttt
    14041 tgcctgaaaa gtcaagctga cagcagcaag ttcattttct ttgttacgca agatagtgac
    14101 ggattgttcg tccacgcctg tttcaaaagg aaccattgta gaggcaacta cttcaggttg
    14161 agagctcaaa aagaaacgag cgaaagatac agcatacgta ccgatatcca acagagctcc
    14221 tccagctaat tctggattga agaaccggtt tttagggtct ggttctttgt aactgccgaa
    14281 aggtgcttgg atcattttta aagcccccag ttttcctgta tccattattg agcgtaactg
    14341 ctgataaagt ggcatgttga agattgtcat cgcttctgct aagatcaaat tcttttcttc
    14401 tgctaagcgc atagcgtcag ccagttcttt tttattcatc gtgatggctt tttcacatag
    14461 aacgtgtttg cctgcttcca atgctgccaa gatatggtcg atatgctgtc tatttggtac
    14521 agcaatgtac acgatgtcga tttcagcatc gtctaacatt tcttgatagc ttccgtaagc
    14581 ttttggaata ttgtaacggt gagcgaagtt ttccgctttt tctgaagttc tggaagcaac
    14641 tgctgttagt tcgctcgtct cttgattgaa gctttcggca aactcatgtg cgatggtacc
    14701 aagaccaacg attccccatt gatatttttt catctgaaaa cgctccttca tagttggatt
    14761 gagtttcttg tctgtctatt attataacaa aaatcacgaa gaataaagag gagaggactt
    14821 gaaacattaa aaaaaatgaa agcagcgatt taagaggtgc tttttgatca aaacttaagt
    14881 agaatagtta aaaggagggg ataaacgtgc atcaagtata tattgatctt attatgagtg
    14941 tattattaga acagtttgaa actgaaaaaa attttttaga tgaatacttg ctgatcagtc
    15001 cagaacaatg gcaaaaatgg aaagatggcg agaaaaatct gccatctgaa gcgatgcaga
    15061 aagtaaaaaa tcttttcact gattatgaat ggatgctaac gcaaaagatt ttgcgtcaaa
    15121 cgattatttt tcccgaaaaa cgaaacgttg ccgttgcaga gtacaagcaa atcaaaacac
    15181 gcatcgcgca aaaatggctt agcagcaaag cagcaaaagt cgagctgatc cctttgaaaa
    15241 ataatcagca ggctggtaga taccttgact tgaaagtaag tattcaatat gatgaatggg
    15301 gctatgatga tattttgaat tttcgtctgc cagcagatgt tcaaaaacag atcgaaggag
    15361 aaaaaatcga acttctcgat tgggtgaatg aaaatctgga agaaacttac gttcatgagg
    15421 cgaatgggga acgtgaagaa caacgaaagg atttttcaag tgaataaatt tttaggattt
    15481 ggagcagttg tgattatgat cgcagcaatg ggctatgtta tttttagcga tgatgattcg
    15541 catgttcaag ccggcaatca agcagtcgaa cgaacaagca ccaaaacaac tgctagtaaa
    15601 gaaaagaaca gtcaaacaac cagcagcaag gtaaaggaca aagaaacaaa agatcgtacg
    15661 tccaaacaat tgccagatgt taaaacagac gattggaagc tagttttggt tggtccagat
    15721 cacaaattag aaaaagaaat tgatgagtct actcaattgg catcattaag taacggatac
    15781 ttgatcgaca aacgcattgc tccagaatat gaagcatttg ccaaggctgc tgaagcagct
    15841 ggatttccat tagtgatggt ctcagcttac cggtctgtat catcccaaca acaagttttc
    15901 gaacaaaatg tccaagatgt gatgagtcgt caaggtgtat cagaagagga ggcgacaaag
    15961 attactaaag aaacgattac ggagccagga tacagcgaac accacacagg tctggcagtc
    16021 gatgtcgtcg atcaaaactg gtacaacagt tatccttcta ctgtattgga tgcaagttac
    16081 ggagatcagc ctggagctaa atggatcgca gataatgctg cgcagtatgg atttatcgtt
    16141 cgttatccaa aaggacacga agatataact aagatcacat atgaaccttg gcacttacgt
    16201 tatgtcggta aagaaaacgc tgagtatatc accaaacacc aattgacgct agaagaatat
    16261 ctgaatgaat taaatgaaaa gtaggaattg atcatggcga aaaaaaagtg gaaaaagcaa
    16321 aagcgcaaga atatccgttg gccagcagtg gttgccggtg tagcagtgat actcttagcc
    16381 tttgtttttt ccttgaagaa tctgtcttct ccttttactg ataatcagca agaaaatgaa
    16441 gcgcaatccc atcagcaatt tattgaacgg cttgttccgc atgcccaaga actacaagat
    16501 ggttatggag tgcttcctag tatcatttta ggacaagcta tattagaatc aaattgggga
    16561 aaaagtacct tggctagcaa atacaataat cttttcggga tcaaggctta tggggatcag
    16621 aagaaagtaa gcctggaaac aaaggaattt gttaacgaag aatggataac tatccaagga
    16681 gacttcaaag tgtatgattc atgggaacag tccatggatg accatacaca actgttcgtc
    16741 caaggagtag attggaatcc tgcgctgtat gaaaaagtga ttacggccac caactatcag
    16801 gaagccgcac aagcattgca agatgcaggt tatgcgacag accccggtta tgcgcaaaaa
    16861 atcatccagg tcatcgagac gtatcaattg aatcagtatg accggagata gcaaaggaga
    16921 agtggctgat ggcagaacaa tttacgccag aaatcatgac ggaattgaga aaagatatcg
    16981 taagagtacc ggaaatcatt ttagaagcaa gcgggatcaa gatatttgga aaattgatcc
    17041 gttcgatcat ctttactacg gatattgcga tcatacgtaa tacaaatgcg aatgcagtaa
    17101 ttgctgtgta tccttttaca cctcatccag cgattactaa aagcattatt gaggcagctg
    17161 acattccagt tttctccggt gtaggtggtg gtttgacaca aggtgctcgt tcttcctaca
    17221 tgagcatgtt cgcagaagcg caaggttcgt taggggtcgt tttgaacggt cctacgcctt
    17281 tagagacagt aaaagaagtt tgtcgagtag ttgatattcc agttatcagt acggtaacgt
    17341 cgaaatatac agaaatagat gaaaagttag cagctggtat ttcgattatc aatatcagtg
    17401 caggtaaaga aactgcagaa gcagtacgcc attttcgtaa aaaatatcct gaacttccta
    17461 tcattgcgac aggtggtcca acggaagaaa gtattgctga gaccattcaa gcaggagcaa
    17521 atgccatcac atatacgcca ccaagtagcg gagagctttt tagtcgtaaa atggaaaaat
    17581 atcgggaaac tgagaaaaag aatcatgaat aacaggtgag aatcaaaaga cgaggaagag
    17641 cagatagtgg ctcttcctcg tcttttgtac tccagtacta tttgttcaga attcaaaaaa
    17701 aagagaaatt tttttgtttt tttacctgta atgtacataa gaagagttaa aaccttttgt
    17761 tattattagc attctaacaa aaaaatgtct tgatttattg aagcgctttc tatagaatga
    17821 aaaacgaata aaaactaaaa aaggcacccg acaatttagt agcagctaaa ttgtcggggc
    17881 ttgaaaagtc agcgggaact gaccaatcaa gttgccatag tcaatgcttg tgcatcgacg
    17941 tgtatattgt acctaatttc atacagaatt actagttatt tttctgtttt ttagggaaga
    18001 gcgcacacga agaagcatgc ttatttagct atgtcaagga tattgggcag ttgtctgata
    18061 tccttttttc tttgcgtaat tatcctccca tcattgaagc aagaagtgtt tttagcgatg
    18121 aaagaagaat cagcactatc taatttttct tgaaagtatt gagttgttca tcctaggcag
    18181 aacgataagg caagtcttgg tttttattcc ccttgaaaaa gatcgtttaa taaatatgtt
    18241 ctgtataaaa atacagtata ttgaaaaata acaatggaag tagaggtgca gagaatgaag
    18301 aaaagaatga gaatcatctt agctttaagt gttatgttat tcttcttgac ggcttgtggg
    18361 caagaagatg acaaaaaaat cacgctgaac atggcttggt ggggttcgca agtccgacac
    18421 gatgcaacag taaaagtaat cgagctttat gaagaaaaaa atccccatgt gacgatcgat
    18481 tatgaatttt atgattatga aggatattac acaaaattag gtacactagc agcatcagat
    18541 gatatctggg acattttcca actgaacaat caatttcctc aatacatcaa tcagattgaa
    18601 ccattagatg aatatgtgga gcaagggata attgatattt ctaatgcaga tgaatcctat
    18661 ttagcaacga cgacttacga cgggcaatta gttggactgt ctaacggggt gaattcgttt
    18721 gcgattgctt acaataaaaa tatatttgaa caattaaata tccctgaacc agcttcaaat
    18781 tggacatggg atgaatttga acaaatcagc tatcaaatca ctgaagaatt aggaatctat
    18841 gctatttcaa gattcgaaga ttttatagct ggctgtatta ttcaaatacc acaagttgag
    18901 aaaggattga atttttataa tcgggaagat ctatctaaca gcttgggatt tgaaaatcca
    18961 gactatctaa cagatttttt ccagctgcgt aaaaatctgg tagacaaagg ggcccatcca
    19021 gaaccaggtg gtggagctgc aagtacgacg gatctgtctt ttcaggcggt tagggataga
    19081 gaagcggcaa tggtgtttct atcaagtaac cagttgacag aaatattgtc aggggctcct
    19141 gaagatatgg agattcagtt gattaatcca cctcgcagaa aagcagatgg agaatctggt
    19201 atccctttac gttcttcgca aatgctgagt atggcaaaaa gctcagccca taaagaagaa
    19261 gctgctaagt ttattgattt ctttcaaaac agtgaagaag ccaatgaaat tttaaaagga
    19321 gaacgtggtg taccaatcat gtcgaatatt cgagaacagc tcgctcgtgc agatgatgca
    19381 actttgcaag cgacatttga ttatttagaa atgatttccg atatggacaa cggcgaagtg
    19441 aatgtctttg atagtgcttt gaatccggaa attcaagacc aatacaatct tttagttgaa
    19501 aaagtcattt atgaagaagt aacagcagaa gaagcagcag agagtcttta tgagtttgcg
    19561 tcaaacattc taggatagca gcaggaggaa ggcatgaaaa aagaaaaact aaaacggttc
    19621 ttggatcaag acaatgtggt cggttacgta tttgcttctc cattcatcct aggatttcta
    19681 ttgataacag tgataccgat gatcttgtca ctttattatt cgttcaccga ttatcgtttg
    19741 ggaaatccag tctcatggat cggcttggat aattatataa agatgctgag tgatgcccgt
    19801 tttttgaact ccatccgagt cacttttctc tatgtatttg catctgtacc tgtgaaactg
    19861 atctttggtc tattgattgc ttatctttta acgaggaata tcaaaggaac gactttcttt
    19921 cgttctttgt attatgtgcc tagtttgatc ggtggcagta tttctatcgc tctagtttgg
    19981 cgggagttgt tttctaaaaa cgggttagtg aatattttcc tggaacgatt aggcgcacct
    20041 gcgctttcct ggtttagcga tcaaaaactg gtcatgatcc ctcttgtttt gatgtctgct
    20101 tggcaattcg gttcggcaat gatcatcttt gctgcaggta tcaaagagat cccaggctcg
    20161 tattatgaag cggcagagat cgatggagcg aacaaatggc agacgtttta caagatcacg
    20221 ttacctcttc tttcgccgat cattttgtat aacttggtta tgcagacaat cgcggcgttt
    20281 atgactttta cgcaggcatt tatcattacc caaggtggtc cgaatgatgc cacgaacttt
    20341 tatgctcttt atgtgtataa ccaagctttt tcttttaatt ctatggggta tgctagtgct
    20401 atttcgtgga tcatgctgtt gattatggga gctgtcacct ttctgatttt caaatcatca
    20461 aaaaaatggg tcgttgtgtg aatgagagga ggaagaaatg aataatacag taacgaaatg
    20521 gtttcaatac ggttttattt tgctattagg tctagtcatg atttatccgg tcttatggat
    20581 gatcgcaggt tcttttaaaa cggatcaaga gattatgagt ggttcgctga atttgattcc
    20641 agagactttt caatgggaaa attacgcaaa aggatgggcg gggtttgctg gaatttcatt
    20701 ttttactttc tttaggaatt cgtttgtcat ctctgcagtt tcgacgatag ggacagttct
    20761 gagctcgact tgtattgctt acgcattatc gagaatcgat ttcaaaggaa aaagattctg
    20821 gttcgtcgtc atgttagtaa cgatgatgat tcctgcacaa gtgattttga ttccgcagtt
    20881 tattatttac aatcggctga atttggttgg gacgtatgtg ccgctgattt taccacattt
    20941 ttttggacaa gcatttttca tttaccagat catgcaattc atggtcagca tccccaaaga
    21001 gttagatgaa tcagcgatta ttgacggatg cagcaagtat agtgtcttta ccaaaattat
    21061 ttttcctttg ctgaaacctt cgatcatcac gacgatcatc atccagtttt attggaaatg
    21121 ggacgacttc atgggaccat tgatttattt aaacaagccg agatcttaca cggtatcgat
    21181 tgccatcaaa ttatttgcag acgctggatc tagtacgact tacgcgagta tgtttgcgat
    21241 gtctacgttg tcgctgctac cggtttttct gattttctta ttcttcaata aatatcttgt
    21301 ccaggggatc agtacaagcg gtctgaaggg ctgaatatga aaaagccaat agaagagatg
    21361 tttctttaca agctcaacta ctatgtctgt cggatttttt taaccagtct tatcagtaat
    21421 gctcttttcg ctttagttct aggatgtttg ttcactttag gattagtgct gtctgctcgt
    21481 gttgtctatc tgatttattt tttgatgatg tatccttctt attatctatc tgtccattac
    21541 ttggcagaaa aaaaggtatg ttggaggaaa ggaaaaatca aacggatgtg tttcatcatt
    21601 acgttgtttc agctgtttgt cattattttt gcagttgatt ggtatttatt agtgggaaag
    21661 attggagctt ggtatctgat tccttttcta ttgtgtctgt tgctttttgt atcccatagt
    21721 ttttttagta cgctaattga tatctgcaaa gaagataaag cagatagtct tgtttatttg
    21781 atcaaaagga atatctggct gttgtcaaaa aacgtcaagg ggtttctgtg gtatttatgc
    21841 cttttgtatg gactgttctg gtgtatacag catgattttt tactcactgc attactgtat
    21901 ccagggctgc catttgtcac agtattttgc ttaaaagaaa aggagaatga ctttaaatga
    21961 agaaaaaata tgtacaagtc ggacttggtg ggagagcgcg ttttttttat gaggcaattg
    22021 cctctacgta tcatcaaact tgtgaactag tcggtttttg tgatgtatct caaacaagga
    22081 tggattatgc aaatcggata cttgtgaaca agtatggaca gaaaaaagta aagacatgta
    22141 tgccatcaca atttgagcaa ctactggatg acgtacggcc ggctgaagtc attattacgt
    22201 cagtagatcg aacgcatcat gattatatca ttcgtgcaat gaaaaaagga tatgatgtta
    22261 tttgcgaaaa acctctgact atcgatgagg aaaaagctca agaaataata acggtccaaa
    22321 aacagacggg aagaagcctg cgagtcactt ttaattatcg ttatgcaccg tatcacacga
    22381 agataaagga actgatagaa agtgatgtga ttggtgatgt gttttctatc cacttcgaat
    22441 ggctgttaaa tacgcaacac ggggcagatt atttcagaag atggcatcga aataagcaca
    22501 atagcggcgg gcttcttgtt cataaatcta cccatcattt tgatctagtg aatttttggt
    22561 tgaacagccg tccccaaaag gtatttgcat tcggtggatt aaacttttat gggatgcata
    22621 atgcggagaa acgcggagta gaaatatttt acagtcgatg ctatggaagc gaactagcta
    22681 aagctgatcc atttgctata gacctgtcag ccaatgagga attgcgagaa atgtatttag
    22741 aagcagaaaa agacagtgga tatattcgtg accgcagtgt attttccgat gatatctcta
    22801 ttgaagatac actaggcgta acggtcaaat atgaaactgg tgcgattttg acgtattcgc
    22861 taaacgcgta tatgccgtgg gaaggattca atgtttcttt caatggcagc aaaggacgga
    22921 tcgaaatgaa agtgatcgaa aagtcttaca tcaatgcagg tggagataaa aaggatgaag
    22981 gagcagccgt tcttcagtcc atccatgtct atccgatgtt cggtgagcca tatgaggtaa
    23041 tcgtcgaaca agaagcgggc ggacatggcg gaggagatcc gcgtttatta gatgatctat
    23101 ttggtgaaga aaaagaagaa gatccgtgga atcgggcagc aactcacgta gatggtattt
    23161 tgtcgatttt gacaggaatc gcagcaaatc attctattgc ttcaggaaaa gcagtagtga
    23221 ttgacgagct tgtcagctta aaagaataag aatagattta cggaaattac ttcccgtagt
    23281 ttataaaatc ttgccttatt gccgataggc tgtcttttga acactattta ttcggaaaaa
    23341 ggggctatga catgcttttt gtcatgcctt ctttttatgt gggctgcttt tttagatagg
    23401 agaaaataaa aataactatt taaacccgaa caaaaaggaa taatgcatta aaaatcatta
    23461 gattttacaa aaaaataagt aaaccacgtt gtcagtttca gaaagtagtg ttagactgtt
    23521 ttcaatattt gaaacaacat tttttattca aatatggcaa actgccttca cgtgcaaaac
    23581 agttgcaaga aaatgaattt acactattat tagttttaca tacctactta tatatcgtca
    23641 taatatggat gacagtttct agccagtacc gtaaatgctg gactataagt aaaagattgg
    23701 ctatttcacc cttcttttct tatgataaag tggagggtgt ttttctttaa cagaaacata
    23761 gtaggttttt gcacaaaagc ggttatttcg gtattaataa atgataaagg agcaaataaa
    23821 gtgaaagaat tagttgaacg tattcaaaaa gacggacgta tattaggcga gggcgtatta
    23881 aaagtcgaca gcttcgtcac tcaccaagta gaccctgtat tgatggaaca aatgggaaaa
    23941 cggtttgcag aagtatttaa agaacaagga atcacgaaag ttgtgaccat tgaagcttct
    24001 gggatcgcac cagctttatt tgctgcaaga gaattagatg ttccaatgat cttcgctaga
    24061 aaagcaaaaa gtttgacgat ggatgaagaa ttattgacag cttctgttta ttcttttacg
    24121 aaacaagtga caagtacgat ttctatttct cgtaaatttt tatcttcaga agacaaagta
    24181 ttgattatcg acgatttctt ggcaaacgga caagcggcaa aaggattgat cgaattatgc
    24241 cagcaagctg gagcgcaagt agaaggaatc gggatcgtca tcgaaaagtc tttccaagat
    24301 ggacgtcagt tacttgaaga aatgggattg agagtcgttt ctcttgcgcg tattgcttcc
    24361 ttgacgaatg gacaagttga gtttcttgag gaggacgcat aatcgtggaa aaagaaacac
    24421 aaaatggaaa agctgcggtt ttagggctgc agcatctgct agcgatgtat gcaggagcag
    24481 tagcggtgcc tcttttgatc ggtacaggac taggctttaa tcaagaacag atgacttatt
    24541 tgatttcaat tgatatcttt atgtgtggat tagcgacatt attgcaattg acagttaacc
    24601 gatttttcgg aattggcttg cctgtcgttt taggatgtgc gatccaagca gtagctccac
    24661 tgatcttgat cggaaccaat gaaggagtag gagctatcta cggatctatt atcgcttctg
    24721 ggatctttgt tgtgttagtt tctggtgtct tttctaaaat taaaaaacta ttccctccta
    24781 tagtaacagg aacggttatc accgttattg gtttgacttt gattcctgta gcaatcgaga
    24841 aaatgggtgg aggtaatgca acagcagctg attttggtga caaaacaaat ctgctacttg
    24901 catttgtgac gattctccta attgtaggcg tgcaaatgct ggcaaaaggg ttcattcgtt
    24961 caatcgcggt attgattggt ttagtcggag gaagcatctt agctgctttc atgggaatga
    25021 ttgatctgag cgcgattgga gatgcgccgt tgttccatgt tccacaaccc ttttattttg
    25081 gtaaaccaac tttcgacgta tggtcgattt tactaatgat catcatttcc atggtcagca
    25141 tggtagaatc aacaggtgta tattttgcac ttggtgacat tactgggaaa aatgttggag
    25201 aagaagaatt gaaaaaggga tatcgtgcag aaggacttgc cgttatctta ggcggtattt
    25261 tcaatacatt cccttatact ggcttttctc aaaatgtcgg attggttcaa ctttcgggaa
    25321 tcaaaacaag aaaacccatc tatttctctg cattcttctt gattgtttta ggattattcc
    25381 ctaaaatcgg tgcgttagca caaatcatcc ctgagccggt acttggtgga ggaatgttag
    25441 tcatgttcgg gatggtggca gtccaaggaa tccgtatgct gttggaagtt gatttcagca
    25501 atgataaaaa tctattgatt gttgctgttt ctgttggatt tgggctgggt ttcaatgtta
    25561 cgccgacatt attcagtcaa atgccgcaaa cattgcaaat gttcactgga aatggcatcg
    25621 taatgagtag cattacggct atcatattga atttgatctt taatggattg aaaaaagatg
    25681 aagaaatatt ggaagaagcc ttcaagaagt aatagagcaa aagaaaggtt gtgaaatcag
    25741 cgttttgacc tgattgttag agaaacaaac ggaaaaatag ttcctcgtat tttgccgttt
    25801 gtttgagcta ataccgaggg tcagctgatt gaacaccgtt gaaggaagag gtcgtgagcc
    25861 tgccgttcat ctccgagtca caaggaacaa tttcaaaaaa aagcttctca tgtttgttga
    25921 atattgttcc ttgtgaccga ggagttggca ggagaacacc gtttatccat aaaaaggaat
    25981 gtgacctaac ttttgtcaca ttcctttttt ttatctttaa taaacacgaa caataaaatg
    26041 tttttctttg ttaacattcg aaatttcttt gacatcaaaa aaagtgattg ttaaaatatg
    26101 aatgtagaaa aactgggagg aaaaacaatg acagcaaaaa tctctgtgat tatggggagt
    26161 acttcagatt gggaaacaat gaaagaagca tgtcaaatat tggatgaatt cggtgtgtct
    26221 tatgaaaaaa aggtcgtttc tgctcatcga accccagatt tgatgtttga atatgcacaa
    26281 aacgctcgaa aaaaaggaat caaaatcatt attgcaggag cagggggagc cgcgcatctg
    26341 ccgggtatgg tcgcatcaaa aacaactttg ccggttatcg gtgtaccggt ccaatcacga
    26401 acattaaatg gtttggattc gcttctttcg attgtccaaa tgcctggagg agtacctgta
    26461 gctactacag caatcggaaa agcgggagca attaatgctg gactacttgc gatacagatg
    26521 ctttccatgt atgatttaga attggaggct aaattggctg aaagacgttc aatgttggct
    26581 aaaactgtta tagaaagtag tgatcaactt ggttaaacct ttgttgcctg gttcaacgat
    26641 cgggatcgtc ggtggcggtc aattaggtcg tatgatggcg attagtgcaa aagaaatggg
    26701 ctttaaagta ggtgtgctgg atcctgtgag cgattgtcca gccgcacaag ttgcagattg
    26761 gcatattgaa agtgtctatg atgacacctt tgcgctgaaa gagcttgcca gaagaacaga
    26821 tgtcattacc tatgaattcg aaaacgtcag tgtagaggcg ttaaatgcga ttttacccat
    26881 gtcatttatt cctcaaggga cagacttgct tgcgattacg caagaccgcc tgttagaaaa
    26941 atcttttttg gaaacgaata acatcgtgat tgctccttat gcaacgatcg tcagtccgac
    27001 ggatatccaa gatgcgattg acgggatcgg ctatccttgt gttttgaaaa ccactcgagg
    27061 cggctatgat ggcaaggggc agtatgtttt gaaaagtcgg gcggatctag ctcctgccat
    27121 ggacctttta agagaaggaa cctgtgtttt agaagcatgg atcccgtttg aaaaagagat
    27181 ttcgatcatg gtggcaggaa atggtcaagg agatttcacg acttttccgg tcgtggaaaa
    27241 catccaccac aacaatattc ttcatgaaac gattgctcca gccgcgattg atcaggatgt
    27301 gatcgaggag gctgagcgta ttgcccgtgt gattgcagaa gcagtgagcc tttcaggtgt
    27361 tttaggggta gaaatgtttt taacaaaaac aggcgggcta tatgtgaatg aattagctcc
    27421 tcgtcctcac aattctggac attattctat tgaagcttgt tctatgagtc agttcgatgc
    27481 ccatattcga ggtatttgtg gttggccatt aggagaaaaa gtacgtttga taagcaatgc
    27541 agtaatggtc aatgttttgg gagaacaact gctggaaagc tatcgcttga ttgagaataa
    27601 gccagactgg caattccatt tctatggaaa aaaacaagca aaaaaaggtc gcaagatggg
    27661 acatatcact atcttgacag aagacatcca gcaaacgctg gaagaaatca aacaaacgaa
    27721 tatttgggat tagaggagaa aaaacatgtt agaacgttat acacgccctg aaatggggaa
    27781 tatctggacg gaagagaaca aataccgtgc gtggctcgaa gtcgagattt tagcagatga
    27841 agcttgggca gaacttggtg aaatcccgca agaagatgtg aaaaaaattc gtgagcatgc
    27901 atcatttgat atcgatcgga tcttggaaat cgaaaaatta acacgccatg atgtcgttgc
    27961 gtttacacga gcggtttctg aaacattggg agaagaaaga aaatgggtcc attatggtct
    28021 aacaagtacg gatgtcgtag atactgctta tggctatctc atcaagcaag caaatgatat
    28081 tttacgggaa gacttgaaac gttttacgga aatcattggc gaaaaagcaa aagaacacaa
    28141 atatacagtg atgatgggtc ggacacacgg tgtccatgct gaaccaacta cttttggatt
    28201 gaaacttgcc acatggtatt cagaaatgaa acggaacatc gaacgatttg aacatgcggc
    28261 aaaaggagta gaagcaggaa aaatctcagg agcagtggga acgttcgcaa atatcccgcc
    28321 atttattgaa gagtatgtat gtaaacaatt ggggatccgt ccacaagaaa tttctactca
    28381 agttctccct cgggatctac atgctgaata tttctcagcg atggcgctta ttgctacaag
    28441 tattgaacgt tttgcaacag agatacgcgg attgcaaaaa tccgaaacac gtgaagtaga
    28501 agaatttttt gcgaaaggtc aaaaaggttc ttctgctatg ccgcacaaaa ggaatccgat
    28561 cggttcagaa aatatggctg gtctagccag agtggtgcgc ggacacatgg tcactgccta
    28621 tgaaaatgtc acattatggc atgaaagaga tatttctcat tcttcagcag aacgaatcat
    28681 cttgcctgat accacgattt tattgaatta catgttaaat cgttttggca atatcgttaa
    28741 aaatctaacg gtctttcctg aaaacatgaa gcggaatatg tctgcaacat ttggtttgat
    28801 ttatagccag cgcgttatgc tgaaattgat cgataaggga atgacaagag aagaagctta
    28861 tgatcttgtt cagccaaaaa ctgcgtacgc ttgggacaac caagtgcagt tccgcccgct
    28921 gttagaagaa gatccaacca tcacatcggt attatctaaa gaagaaatag acgatgcctt
    28981 tgattatcat catcatttga aaaacgttga cgtgatattc aaacgagtag gtttggaata
    29041 aagaagagtg agttgcaaaa ttcaattaaa atagaatagc aaaaataacc aaaaaagaag
    29101 cagatccgtt agcggttctg cttcttttag tttattatat tttcttatca ataataggaa
    29161 cctgatttta aaagcggcta cctctttacc gtgcctcttt acatacaaaa aatagaggaa
    29221 ttaagcgtaa atggcttggc tattataact aaaatgctgg ttatggagat gttgcagcaa
    29281 gttttcgaga aaagcgtatt ccatctcttg tccattgaat aagatctgga tacgataatg
    29341 atttttgaaa cgcttctgtt catgaatctg actgattgaa agttcgcctt tgtgttctgt
    29401 ctgataaaga aaagtccttt tacggcattc agcacagcgc ttggttgctc ggcggatttt
    29461 tcggaatgta taaaaactag tatctttatt gcataaataa acgtctttga tcgacagcaa
    29521 atcattatat agacaggaac gttcttcagc tgttaattct gataaaaaaa gctgaccttg
    29581 ttttattgca tcttccatcg gcaagtgcct cctcgaaccc attatccaaa tttttagtta
    29641 attctaatat accatcatta agtataaatg taaacgcttg ttgatggtat aagattttcg
    29701 tttctgataa aacacgaaca ttaaaagaat ctaatgcctt aaatgtacat atttttgttg
    29761 atttataaaa agatgattgc taaaatttaa agtgaaaaaa cgaacaaaaa acgatgtatt
    29821 tgcttttaat gtaaataaaa aggagagacg tacatggaga agaaagaact tttgtatgaa
    29881 ggaaaagcca aaaaaatata tcttacttct gatgagaact tgatttggat agaatattta
    29941 gatcaagcaa ctgcgttgaa tggcgcgagg aaagaccaga taagtggaaa aggagaattg
    30001 aataatcaaa tcacaagtgc aattttccgt tatctgactc aaagaggaat aaaaaatcat
    30061 tttattgaac aattgtctaa aaccgaacaa ttagcaaaaa aagtacaaat tatccctctg
    30121 gaagtggtta tccgaaatat tgcagcagga agtttctcaa aacgtctagg tgttcccgaa
    30181 ggtaaagaat tcatcaaacc aatcattgaa ttctactata aggatgacca gttggatgat
    30241 ccatttatca atgaagagca tatctatttc ttacaacttg caaagccgga agaaatcagt
    30301 gagctgaaag cccaagcgtt ggctattaat gaaattttga ccgaattatt tgctaaggtc
    30361 ggtttggttt tagtagattt caagctagaa tttggccggt cgaatggaca aattttgctt
    30421 gcggatgaag taacaccgga tacttgccga ttatgggatg aacgtacgaa tgaacatatg
    30481 gacaaagacg tttaccgcag agatctaggt gatttgatcc cagtctatca agaagtatat
    30541 aaccgtctat cggaactaac tgaagaaaag gagcgagtat gatgtatttc gtaaaagtat
    30601 atgtaaccta taaagattca gtgttagatc ctcaagggga ggcagtaaaa aaagcagtcc
    30661 atcgtatggg atatgaaaca atcgaagata tccgaatagg aaaatacttt gagatacaac
    30721 ttgctgatgc agaagaacca atcgatacag tgattgaaac gatttgtgac aagctgcttg
    30781 caaatgtaaa tatggaaaca taccgatatg aaatcaaaaa aatggaggaa gtataacatg
    30841 aaatttgcgg tcatcgtttt tccaggttca aattgtgacg cagatatgtt atgggcagtt
    30901 cgcgagatca tgggcgctga tgccgaattt gtacggcatg atgagtcctc tttagaagga
    30961 tttgatgggg ttttactgcc gggaggattc tcctatggtg actatttgag atgcggtgcg
    31021 attgctcggt tttctacaat catggaagaa gtgattcgtt ttgctgaaga agggaaacca
    31081 gtattcggta catgcaatgg attccagata ttgacagaag caggactttt gccaggtgta
    31141 ctgagacgaa atgagtcttt gcattttatt tgcaaaactg taccattgaa agtcaacccc
    31201 aagacggcct ttacttcaga gtatgaagcc gacgaaataa tctatcttcc agttgctcat
    31261 ggggaaggaa attatttctg tgacgaagaa acacttcaag aactaaaaaa aaataatcag
    31321 attgccttta cttataatga caacatcaac ggcagcgtgg aaaacattgc agggattacg
    31381 aacaaagcag ggaatgtgtt aggaatgatg cctcatccag aacgtgcagt agaagacttg
    31441 ctaggatcag aagatgggaa acggttcttt gcttccattt taaaaaactt cggaaaggtg
    31501 accgtataga tgaaaacatt gaaagaaccg acagctgaag agatcaagaa aaaaagaatc
    31561 tatgccgaat ggggattgac tgatgaagaa tatcgaatga tcgaagaaga tatcttagga
    31621 agaatgccta attatacgga aactggactg ttttctgtta tgtggagcga acattgttcc
    31681 tataaaaatt ctaaaccggt tctacgcaaa tttcctacta gtggacctca tgtgttgcaa
    31741 ggccctggag aaggcgcagg catcgtcgac atcggtgatg gactagcagt tgtcttcaaa
    31801 gcagaaagtc acaatcatcc ttcagccgtg gagccttatg aaggagctgc gacaggagtt
    31861 ggcggaatca tcagagatat tttcagcatg ggggctcgtc caattgcgtt gctagattca
    31921 ttgaggttcg gcgaattaga taatccaaga acgaaatatt tactagaaga agtagttgca
    31981 ggtatcggcg gatacggcaa ttgtatcggc ataccgactg taggcggcga aattgcattt
    32041 gatccttgtt atgaaggaaa cccattagtc aatgcaatgt gcgtaggttt gattgaacac
    32101 aaacatatcc agaaagggca agccgctggc gtcggtaatt cgatcatgta tgtaggtgca
    32161 aaaacaggtc gcgacggtat ccacggagca acttttgcct cagaagaatt taatcaagaa
    32221 gaagaacagc aacgttctgc tgtacaagta ggcgatcctt ttatggaaaa gctgctgctt
    32281 gaagcgtgtt tggaattaat cttgcatcat tcggattctc taataggtat acaggatatg
    32341 ggagcagcag gacttgtttc atctagtgcg gaaatggctt caaaagctgg ctcaggactt
    32401 atattgacat tagatgaagt cccacaaaga gaaactggga tgacacctta tgaaatgatg
    32461 ttatcggaat cacaagaacg gatgttgatt tgtgttaaat caggagagga agaaaaaatc
    32521 caagaactat ttcagaagta tgatctagat gcagtcacta tcggtaaagt aacagacgac
    32581 gggcaatatc ggctatatca tcaaggagaa gaagtagcaa atctgccagt cgatgcatta
    32641 gctgaagatg caccagttta tcataaagaa atgaaagaac cagctcgaat cgtagaattt
    32701 cagcagttag ctccttatca gccagttatc gaagaacctg gacaagtatt gcttgatctg
    32761 ctgcagcaac cgacgattgc ttcaaaacgt tcaatctacg aaacttatga ttcacaagta
    32821 caaaccaata cagttgtccg tccaggaagc gatgctgctg tgatgagggt tagagggacg
    32881 aataaagcgt tagctatgac cacagactgc aacgcgcgct atctgtattt ggatccaaaa
    32941 atcggaggac aaatagcagt ggcagaagct gctagaaata ttattgctag cggtggtaag
    33001 cccttggcga tcaccgactg cctgaactat ggttctcctg ataaaccaga agttttttgg
    33061 gaattatcga cttcagctga cggaattgct gctgcgtgtg aaacgttagg aactcctgtt
    33121 atttcaggaa atgtctcttt atataatgaa acggatggtc aagcaatcta tccaacacca
    33181 atgattggta tggtcggatt gattgaggat cataaacata tcactactca ggaattcaaa
    33241 aaatcagggg atctaatcta tatattaggt aagacgtttg cagattttga tggcagtgaa
    33301 ttacaaaaga tgcagcttgg aagaatcgaa ggtgtgatcc gaaactttga tctatccatt
    33361 gaaaagagaa accaagagtt agtattgaca gccatccaaa acggattgat tgaaagtgct
    33421 catgactgtt cagaaggtgg cttggcaatt gcactggcag aatcagcttt caaacatcag
    33481 ctagggatat ctgtacagtt tgaattgtcc tctgctcaat tatttgcaga aactcaatca
    33541 agatttgtgt tgacagtcgc accggaaaat aagacacgat tcgaagaaat gatgggagat
    33601 gctgctgttt tagcaggtaa ggtgacggat gaagcgataa tcgaaatttc agcaactgac
    33661 ggtcagatca aaatagaaac tgcagtagca agaaagtgct gggaggatgc aatcgtatgt
    33721 cttatgaagt gaagagttta aatgaagaat gcgggatctt cggtgtttgg ggtcatccag
    33781 acgccgctag tgtggcatac ttcgggctcc atagtcttca gcatcgagga caagaaggtg
    33841 caggtatcgt gtccaatgat cgaggaaagc ttaaggggca tcgagatttg gggctgcttt
    33901 ctgaggtatt caaagatcaa agaaaattgc agcagttaac aggagaagct gcaatcggac
    33961 atgtacgtta tgcaacagca ggcaatggaa gtgtggacaa tattcagcct tttctattca
    34021 aatttcatga tcagtcgatc ggcttagcgc ataatggtaa cttgatcaat gctcgttccc
    34081 ttagaaaaga gttagaggaa aatggggcga tcttccattc taactccgat acggagatat
    34141 tgatgcattt gatccgacga agtgaagaaa cagatttttt aaataaatta aaaagtgctt
    34201 tgaatgaagt caaaggtggc tttgcctatt tattaatgac agaaacggca atgattgccg
    34261 ctttggaccc aaatggtttt cgtccattag caatcggaca aatgaaaaac ggagcatacg
    34321 tgattgcctc ggaaacttgt gcattagaag ttattggggc acgttttata agagatgtcc
    34381 agcctggtga gatagtgatc atcaatgacg aaggaatcca gattgattgc tttacgaagg
    34441 acacgcagct ttctatttgt tcgatggaat atatctattt tgccagacca gattcaaaca
    34501 tcgcagggat caatgtgcat actgcacgga aaaatatggg acggaattta gcgaaagaat
    34561 cgccagtaaa agcagatatg gtcgttggcg tacctaattc ttctttgtca gccgcaagcg
    34621 gttatgcgga agctagtgga atcccttatg aaatcggatt agtaaaaaat caatacattg
    34681 cccgaacatt tatccagcca acgcctgagc taagagagca aggtgttcga atgaaattat
    34741 ctgctgtacg aggagtagtg gaaggtaaaa aggtgattat ggtcgatgat tcaattgttc
    34801 ggggtacgac aagcagacgg atcgtccatc ttttgaaaga agcaggggca aaagaagtcc
    34861 atgtgaggat tgcttctcct cctttgaaat atccatgttt ttacgggatt gatattcaaa
    34921 cgcgtaaaga actcattgcg gcaaatcaca cgattgatga aatcaaagaa tgtatcggtg
    34981 cagattcttt aggtttttta agtgaagagg gtctgatcga atcgatcggt ctggaaaaag
    35041 atgctccgta ttcaggattg tgtatggctt atttcaacgg agattatccg acgccgttat
    35101 atgactatga agaaaaatat caggaatcac taaaagaaaa agtatcgttc ttttaaaagc
    35161 agaccaagaa gggagtatat gaattcaatg gcaaatgcat acgcaaaagc tggcgtagat
    35221 gtcgaagctg gatatgaagt agtagaacgg atcaagaagc atgtcaaaaa aacggaacgt
    35281 ttaggtatga tgggcgctat aggaggattc ggcggttgtt ttgatttatc ggtctttcaa
    35341 ttaaaagagc cagtccttgt ctcggggacc gatggcgtgg ggacgaaatt agcagtggca
    35401 atcgaagcag acaaacacga tacaatcggg atcgactgcg tagcgatgtg tgtcaatgat
    35461 atcttagcac aaggcgcaga gccgttatat ttcttagact acttagcaac ggggaaaaat
    35521 gatccgttac gtttggaaaa tgtagtaaaa ggtgtagcag atggatgtgt tcaaggaaat
    35581 atggcgctga ttggcggaga aacagctgaa atgcctggta tgtactcagg taatgattat
    35641 gatctagccg gatttgctgt agggatagct gaaaaatctc aattattgac aggagaaacg
    35701 atcaacccag gagatgtgtt gcttggaata gcatctagcg ggattcattc aaatgggtac
    35761 tctcttgttc gcaaaatttt ctttgagcag cagcagtttt ctttatcatc aaaactgcca
    35821 gaattgaaaa aaacacttgg cgaagaattg cttgagccaa cgaaaatcta tgtttcttcc
    35881 ttgcttccgc tgatcaaaga aaagaaaata aaaggagctg cacatatcac tggtggaggg
    35941 tttgtagaaa atatcccgcg aatgttacca gaatctatgg ctgcacaaat caaacttggc
    36001 tcatggccga ttcttccaat attcggctgt ttacaaaaat atggtgaaat tcctgagatg
    36061 gagatgtatg aaatcttcaa tatgggcatc ggtatggtcc tggcagtcga agaatcgaaa
    36121 gtaaaagaaa tagtacacga aattgagcaa gctggcgaaa aagtttatga aatcgggaaa
    36181 gtgatcgcca aagaaaaaca tcgtgtggtg tttataggag aagaacgatg agaatcgctg
    36241 tttttgcttc tggaaacgga agcaactttc aagcgctagc cgattatcta tcgaaaaaag
    36301 gattggaatc ttcgattgac tggttgtttt gtgatcagcc tgaagcatat gttttgaaac
    36361 gtgcaactgc gttgagtgta ccggcagatt gtttttcacc taaagaattt gattcaaaaa
    36421 aagagtatga agaagcaatt ttgcataaat tgaaagaaaa aaagatcgat ttgatcgtat
    36481 tagctggata tatgcgaatc attggaccgg tattgctgaa aaattatgat aaaagaatca
    36541 tcaatatcca tccgtctctt ttacctgcct tccctggttt gcatggcata cgtgatgcct
    36601 ttgaagctgg agtaaaagaa acgggtgtca caattcatta tatcgaccaa ggtgtagata
    36661 ctggaccaat catccggcag gaaaaagtga gaattgaaca ggaggacacg ttcgattctt
    36721 tagaagaaaa aatccataga gtagagcatc gaatctatcc agaagtgatt agtgaaatta
    36781 ttgaaaatgg aggctatctg aaatgacaag agcattgatc agtgtatcag ataaaactgg
    36841 gattgtagca ttcgcccaag gtttgattga acaaggagta gaaatcattt caacaggagg
    36901 aacaaagcat gcgttggata aagctgggat caaaacgctt tcgatcgaag aagtgacagg
    36961 gtttcctgaa atgatggatg gccgtgtcaa aacacttcat cctaaaatcc atggtggtct
    37021 tttaggaaga cgcgatctcc ctagccatat ggaggcaatg gaaacggaaa atatccaacc
    37081 aatcgacttt gtttgtgtca atttatatcc tttcaaagaa acgattatga aaccagatgt
    37141 cgaaatagca gaagctattg aaaacattga tatcggtggt cctagtatgc tccgtagtgc
    37201 agcaaaaaac catgaatttg tcacctctgt tgttgatcca tctgactatg aagaagtact
    37261 ttcagaatta cgtcagtatg ggcatacttc actttctttc agacaaaaac tagcggcaaa
    37321 agtctttcgt catactgcgg catatgatgc actgatcgct caatacttaa cggattgggt
    37381 ggaagaaaaa gaaccggaaa aattgacact tacgtatgaa cgaaaacaaa cgcttcgtta
    37441 cggtgaaaat agccatcaag ccgctgcctt ttatcagtcc gctcttctgg aaaaatattc
    37501 gatcgcagca gcaaaacaac tccatgggaa agaactttct tataataata tccgagatgc
    37561 agatgctgcg ctacggatca tgaaggaata tgacgagcca acggtagtcg ccttgaaaca
    37621 catgaatcct tgtggtattg ggacagcatc tacgatttta gaagcgtggg aagcggcgta
    37681 tgaagcagat cctgtttcaa tctttggtgg gatcatcgtt ttgaatcgag aagtagatct
    37741 gccaacagca gaacagatgc ataagctgtt tctagaaatc atcattgccc cttcttatac
    37801 acaagaagct ttggaattac tgcaaaaaaa gaaaaacatc cgattactga cagtagactt
    37861 tgcgcaggaa gaaaatcaaa atcgagaaga aacggtctca gtcttaggtg gacttcttgt
    37921 acaagatcaa gatctggcaa tagaaaatga agaagagtgg aaagtcgtga caaaacgtaa
    37981 gccgactcca gcagaagcaa aagcattagt gtttgcttgg agagctgtca aacatgtgaa
    38041 atctaatgcg atcgtactgg caaacgaacg tcagacagta ggaatcggag ccgggcagat
    38101 gaatcgagtc ggttcagtaa aaattgcgat tgaacaagcg caagagaaaa tggaaggtgc
    38161 agttttagct agcgatgctt attttccaat ggatgattcg gttgaatatg cagccaaaca
    38221 tggtataaaa gcaatcattc agccaggagg aagcatcaaa gaccaagatt ctattgatat
    38281 ggcgaataaa tacgatctag caatggtctt tactgatgtt cggcatttta gacattagag
    38341 aggagtcgga taaatgaaca ttttggtgat cggtgcaggt ggtcgtgaac atgcaataag
    38401 taaaaaactt ttagccagtc cgaaggtgga tacggtgtat tgtgcgccag gaaatccggg
    38461 gatgacaaaa gatggtatca attgtgtcgc tatcagtgag cgagatcatt cagcgttaat
    38521 ccattttgtt aagaaagagg ctattgattg gagtatcgtt ggtcctgaag ttcctttgtt
    38581 aaatgggatc gtcgatgatt ttatggcgga aggattgaaa atcttcggtc cgacaaaagc
    38641 agcagctctg atcgaaggtt cgaaaagttt tgctaaacaa ttaatggata cttatcaaat
    38701 cccgacagct aaatccagaa gttttgaatg ttacgaaaaa gcagcagcgt atatcaaaga
    38761 aaatggtgcg ccaatcgtag tgaaagcgga cggcttagca gctgggaaag gtgtagtcgt
    38821 ggctaccaca gtgaaggaag cgctggatgc ggcagaacaa atgttgaacc agcatcgatt
    38881 tggggatagt agcaaaaaaa tcgtcgtaga agagtttttg gcaggagaag aattctccct
    38941 tttggcgttt gtccgtaata ccaaggtgta tccgatggtc atttcgcaag atcataagcg
    39001 ggcatttgat aacgataaag ggccaaatac aggcggaatg ggtgcttatt caccagtacc
    39061 gcaaatttca aaaaagatga ttgaaaaagc tgtggaagaa gttttaaaac cagcggcttt
    39121 gggaatgaaa gaactaggac gctctttcac gggtgtttta tatgcgggtt tgattgctac
    39181 gaaggaagga ccaaaagtga tcgaattcaa tgcgcgtttc ggtgatcctg aaacgcaagt
    39241 cgttctttct cggttgaaga gtgactttgc gcaagtaatc gatgatttat tagagaatcg
    39301 tacagtagag ttaaagtggc agcaagaagg atacaatgta ggcgttgtgg ttgcagctgc
    39361 cggttacccc gaagaatatg agacaggaat ggttctacca gattttctgg aagaagagct
    39421 ttctgtttac tatgctggag tttcctcaaa taacggcaaa ctagttggag caggaggacg
    39481 tctttattta gtagaagcat acggtgagac gatcaaagaa gcacagaaaa aaatttacac
    39541 cgcgttaatg gataaaacga cagatggaac attttatcgt acagatattg gagaaaaagc
    39601 tgccaatagc gaactgatcg tgaagtaaat cagctgcttc catttataaa aaatacaaca
    39661 aacataatcg gaagcgccga ttttagtgaa gccttttcat aaagagtgtg gtacactttt
    39721 gttgtgtata taaataagga ggagttcaga tgaaaaaaat tcaattaggt acttctgatc
    39781 agaaagcagc tgcagtgatc ttaggctgta tgcgtatcaa caatgcggaa gatccagtaa
    39841 aagtgattga gacagcttat gaaaacggca ttgatttttt tgaccatgca gatatttatg
    39901 gaaacggtga atgtgaagaa atctttgcag atgctctagc aaaaacatca atcaaacgag
    39961 aagatctttt tattcaaaca aaatgtggaa tcgttccagg tgtgatgttt gatttttcta
    40021 aaaaacatat cattgaatct gtagaaaaaa gtttgacccg tctgaaaatg gattatgtgg
    40081 atgctttact tcttcatcgt ccagatacat tggtagaacc agaggaagta gctgaagcgt
    40141 ttgatgaatt ggaacggtca ggaaaagttc gttattttgg cgtcagcaat caaaaaccaa
    40201 tgcaaatcga attgctgaaa aaatatgttc gtcaaccatt agtagctaat cagctgcaat
    40261 ttggcttgaa acatactgga atgatcgatc aagggattca tgtcaatatg acagatgaag
    40321 caagtatcga tcatgacggt agtgtacttg attattcccg attgcatgat atgacgatcc
    40381 aagcatggtc accataccag tatggatttt ttgaaggtgt atttatcggg aacgaaaaat
    40441 tccctgaatt aaaccaaaca ttagaagaac tagcagctaa atatcaaacg acaccaactg
    40501 gcttggcttc tgcttggatt ttacgccatc cagccaatat gcaagtgatc gccggtacga
    40561 tgaacgtagg gcgaatcaag gaaatcgctc aagcttcaga aattaatatg tctcgggaag
    40621 attggtacga attgtaccgt gctgctggaa acattttacc ttaaagattg tcataagcag
    40681 gtcaaaaggg ctataaatta aaaagacaga ataacttgaa agctgttttc agcttcgaga
    40741 tattctgtct ttttttattg caaatggaaa gagtatcatt gtacggattt cgtttattag
    40801 ttatttttgt ttttaaggaa aagctgtgtc cgatattctt ttggagaaat cccttgtttt
    40861 ttcttaaata aataactgaa atagttaggg tcattataac caatttcaaa agcaatatct
    40921 gaaatacgat agtctgattg ctgcaataat ttttttgcta attcgattct ttgttctgtc
    40981 agataatcga tgaatgtttg gttaaacgat tgagaaaaaa tcgtactgaa atgagaggga
    41041 cttaatgcaa cttgttgagc gacccaagtt aaggacatat ctggatcggt aaaattttct
    41101 ttgataaaat ccaatgcatg gttcaaaatt ggctgatatt tgttccttga aggctgtgag
    41161 ggcagagcag ttaagaaaga aatgaacata taaactgtcg aacggtaaag cgagtcgtcg
    41221 gcgctgattg ctaagcgttg actggtggat gtgcaatgaa ccatttcttg cgggattttc
    41281 ttttctttca ggcagacatg ctggagtagc ttagtcaaga caaataaacg atataatcgt
    41341 gttcgagttg gtgtgccttg tggtttcgtc aagtgttcga tgtacttaga tacttcgttt
    41401 ttcgataatg aagacaaatc aagtgagagg tcaaagtaaa agacagaatc aactggaagt
    41461 ttcgcttctt gaatcaaatc ctcatagctg ataatttgtt ctttaaggga actggcggtt
    41521 tcaagtatca tctgcgtgat ctcaaaagat gcaggtaatt cgctgattct ttctgcgaca
    41581 ggaccaatgg cgacagaaaa attatttttt tgtccctttt ctaattcatg gaccaacgtt
    41641 tgggctacct gataactggt ctcgatcaca ttttcttcaa gagaatcaac tattaaaaat
    41701 ttgatgaatc gagaggaaac agcagagaag atcacttgtt gattctccct aaataaaaac
    41761 ttcaaataat cactgagatg agcgtaatct tcaaagtctg tactgacttg gtttgctgct
    41821 aataatacgg tcattttttt ccctgctaaa gagcgattga aagattcagc aagtttcaat
    41881 gtttcactga tcgtaagtga gcctttgaac aaaccgttca agaaatgatt ttttttcaat
    41941 tcgaaaacaa gatcagaaga agtgtgcgtt tctttttgct gcaaatctaa agcagttact
    42001 gctttttcta ttgcttgttt caattcgcta cttttaatcg gtttaagcag ataatcatct
    42061 gcctgtacct ggattgctcc tttcatataa tcgaaatcgt cgaatccact aataaatatg
    42121 agacgagtcc aaggaagtag tttccttgct tcttttgaaa aagtcaaccc gtccatgaaa
    42181 ggcatttgga tatcagtcag aatgatgtcg ggctgtaagt cgataattga agacagtgcc
    42241 atctcaccat ctccagcttc gccgacataa gtgattggat aataagaacc aaggacagtt
    42301 atttgttccc gcaagttatt gcgaatgagg tattcgtctt cgatgataaa aactttatac
    42361 atgtttgttt cctccaattg ttttgggaga tagagggatc atcagtgtga cagttgttcc
    42421 ttctcggtat ttgctgtcaa tcgtgatagg tttttgatca tttccgtaat aaagaaggag
    42481 acgcttgttt acgttgtaaa gtccgtagcc gatactgaaa tctgaatcga tccctttggc
    42541 taactcttta cgtatttctg ccagtttttc tgcagggatg ccaatcccgt tgtctataac
    42601 tttgaattgg atcatctcat caattttgca tgtggtaata cgaataaatc ctttgtgacg
    42661 gacgtacttc gttccatggt atacagcatt ttcaatcaat ggctgcaaga tcatttttaa
    42721 aatagaaaca ggaaaaagtg tttctggtat atcgatctta tagtcaagca tatggccgta
    42781 tcttattttt aagatgacta gataatcatt gatatggcta atttcttttt caagaggaat
    42841 ccagtcttgt cctttgctta aagacgtacg aaaaaagccg gaaagtgcat gggtcatagt
    42901 cagagcttct tcaaagcagt cttgttcgat caaagaaata atggcatcca aactgttata
    42961 aataaaatgg ggagtaatct gagcttgcaa tacacgaact tcactttgtg ctaaatggta
    43021 ttgtttcaaa gcgttctccc gtaaagactg gtttagatct tccgccattt tattcatgct
    43081 agcggtaagt gtttgtaatt ccagtgtttc cggcagggtt aaacgaaagc caaggttccc
    43141 tgaagaaagt tgttctgaca tctcgatcag ctgattgatc ggttcttgga cctttctctc
    43201 taaaaagcga cgattctttt tcgcatagaa aaaaatggta ctaagaactc caagttccac
    43261 tattgttaat agaatgagcg agcggacaag tgtcgtattt tttttgcttg ctaagtcgat
    43321 ctccacacga acaaaatctt gtaagatatc tgacagcagt tgagtgacag aatctacctg
    43381 attgatgatc tcttcattgg tatccataaa atcttttgcc aagatattat tgatcagctc
    43441 gttttgataa tcttccagtg tatcgatcgt acgtagcgat acatctaacg tactaatttc
    43501 tttaagtgta tttgtattat ttttgctctc tcgaatatca ttcctaagtt cttctaggat
    43561 attttcctca ttgaactcat ctacggttac ttggccagaa atcaagtccc acatactttc
    43621 caaaactttt tgatcaacct tcaaagcaat tgcatctgct ttttggatat ttgcgatcgt
    43681 ctgttgataa atcaaaagct gttgcgaata taacagtatg ctcagtagca aagggataac
    43741 agcaaataga agcatggctt tgtttgcttg ggcaaaaatc tgttttatgc ttaaattttt
    43801 tgtcatgata cttctccagt caataatttc tggttgggat gttagctata ttctgctggg
    43861 aaaagacagt ctcggaaata aaaatatctt taggtaatgt ttttcctgtt tgaatatttc
    43921 caaaataacg agtaacggta ttggctacat accagccgac atcaggttta cactcgacta
    43981 cacaattgac gattcctgag cgtagcttct cgatcatatc ttcttgtcca tcaatagtta
    44041 caatgatcaa atcttctcca ggtttgattg atgtttcttt tatcgcagct aaagcaccgt
    44101 gagtcatttc atcactatgg ctgtataata catcgatttc ggataaatca tttgtttcta
    44161 aatatcgttt catctggtct tttcctttca tccgaataaa atcaccgaca attcggtgaa
    44221 caatagtcat cggaggttta tggtcgatgg ttccatcttt ttttagggtt ggtttacgat
    44281 tgattgattc caaaaatcct tcggagcgta gcttggtcgg tgtggagttc tctgaaccag
    44341 caagttctag gattctgatt tcctgtttct ttgaatttgt gaagtgattg ctgacaaata
    44401 aacccgcccg atttccttct gctttgaaac tggggccaat gtgggtgacg aaaagctcgg
    44461 gatcattcgt ttgaatatgt ctgtcgacaa gtatgacagg gatccctgct cgctttgctt
    44521 cttttaatac agagtcccac ccggattctt gcaaaggagt aaaaatgatc atatccactt
    44581 tataggcaat gaacgtccgt atatcttgga tttgccgttc ctgattcatg tagccatttc
    44641 ggtagagaac ttggtaatct tctttttcaa gcgcagtgat aattgattca gtatgctttt
    44701 tccgccagct actctccgtt cctgattgcg aaaaaccaac gactagtggg tcaggtgctt
    44761 cctttgtatt aggtgtacac cccatcattt ggtaagcgat tacaacaagg gctaaaaaaa
    44821 ataaaacacg tttcacttta aatcactcca tctggatttg ttagtactat cttatcagat
    44881 aaaagggaaa atcaaagtca aaaggaatca atcgaaaaaa atccaagaaa cttaaaaaaa
    44941 tccaagacaa aaaaagtaca cctaaaaaat ttaaagtaaa tcccataaaa aaatcaatgt
    45001 taacgctttc tttattagct atactcggtg tatcaattga aatgggggat aaaaaatgaa
    45061 aaacaaattt agaaagattg ttgggactat cgctattttg accgcaagca ttctattaag
    45121 tgcgtgtggc aattcaggat ctgcagatga tagtacgggg tatgtaggaa tcgctatgcc
    45181 gaccaaatca gcagaaagat ggatcgctga tgggaacaac atggtctcgg aattagaaaa
    45241 actgggttat aaaacagatc ttcaatatgg agaagataaa gtagaaaatc aagtagcaca
    45301 aatagaaaat atgattacaa aaggggtaga tacacttgtg attgcttcta tcgatggttc
    45361 ggctttaact gatgtgttag ctaaagcaaa agaagcagat atcaaggtga tcgcctatga
    45421 tcgtttactg atgaattcag aaaatgtcga ttattacgcg acttttgata attttggagt
    45481 aggtgtatcg caagcagctt atattgaaga gcacttagga ttgaaagaag gaaaaggacc
    45541 attcacgatt gaattatttg gtggctcgcc tgacgacaac aacgcactaa tcaattacaa
    45601 cggagtgatg tctgttttac aaccatatat ggacaacggt cagttggtcg tgccatctgg
    45661 acagacgagt ttcagtcaaa tcgctacgct tcgctgggat ggttctacgg cgcaagcaag
    45721 gatggataat ctgttaagcg caaattatac tgaccaaaca ttggatgctg ttttgtcgcc
    45781 atatgatcca ataagtttag gaatcatttc gtcattaaaa ggcgtggggt atgggagtga
    45841 aagtaaacct ttacctgtga ttactggaca agatgcgaca gttgctggcg ttaaatcgat
    45901 cattgccggg gaacaaacac aaacgatctt taaagacaca cgtatcttag caaaaaatac
    45961 gattgaaatg atcaaagcaa tcagtgatgg agaagaggtt ccggtcaatg atactgaaac
    46021 ttatgataat ggggtgaaaa ctgtccctac gtatttagca aatacagtat ctgtcgataa
    46081 agataattat caagcagagc tgatcgacac cgattattat aaagaatccg atctgaaaaa
    46141 ttaagaggaa ccaaacaagg aactaaagag atctaagtca gagagaggat aagaattatg
    46201 gcggattgta ttttaaaaat ggcagatatc accaaaaaat tttctggaat ccgagcgtta
    46261 gattgcgtga atctgatgat tgaacgtggg gaaatccatg cattgtgcgg agaaaacgga
    46321 gcgggaaaat caacattgat gaatgtcttg agcggcttgt atccatatgg ctcctatgac
    46381 ggggaaatct tttatgatgg aaagctgtgt caatttaaag atttgaaaga tagtgaagaa
    46441 aaaggcatcg tcatcattca tcaagaatta gcactaagtc cttatctttc aataaaagag
    46501 aatatttttc tcggaaatga acaagcagaa agaggcgtga ttgattggga actgacagaa
    46561 aagaaaacat atgaactgct gaataaagtc ggtttgtcta tcgacccgaa tcttctagta
    46621 tcccagattg gcgtagggca acagcaacta gttgaaatag ctaaagcatt atcaaaatcc
    46681 gtccgtctgt tgattttgga tgagcctacc gctgcattga atgaagaaga aagcgcgaat
    46741 ttgctgagat tgatccgaga gttgaaagag caaggtgtaa cctccatcat tatttcacat
    46801 aagctgaatg aaatcgtgga tatcgcagat cgaatcacca ttttacggga tggacagacg
    46861 attgagacac tagaaaatga aatgatcagc gaagagcata ttattcgcgg aatggtgggc
    46921 agagatttag ttgatcgtta tcctgaaaga aaaccggata ttggagaagt ttattttaaa
    46981 gtagaagact ggacggtcta tcaccctctt gatcacgagc gaatcataaa cgaccacatc
    47041 aacttgcatt tgaaaaaagg agagattgta ggaatagctg gactgatggg agcgggcaga
    47101 actgaattcg ctatgagtct atttggacat tcttatggaa gcaagatatc cggacgtata
    47161 ttaaaggaag gggcagagat atcagttaag accgttcctt cagccattgc aaacggactc
    47221 gcttatgtct cggaggaccg aaaatcttta ggactgaatc tgctgatgga tattcgggaa
    47281 aacgtgacgc tgagcagttt ggataaaata agtcaaaaag gagtattaga taaagaaaaa
    47341 gaagtaactg aggcagaaaa tttccggaaa aagatgcgta taaaaacaaa ctccatccat
    47401 caaattgtca gtagtcttag tggtgggaat caacaaaaag tcgttttatc caagtggctg
    47461 atgacacaac ccgatattct ttttttggat gagccaaccc gtgggataga tgttggggca
    47521 aaatatgaga tctacacgat tatcgaagaa atggcagcaa atggcaaagc tgtctgtctt
    47581 atctcttctg aacttcctga aatattaggg atgtgtgatc gaatctatac gatgaacgaa
    47641 ggacgtatta caggagaagt ctcgcgagaa gatgcagatc aggaagtctt gatgaaatta
    47701 atgacgaaag aagaggtggg ttaagttgga acaggcaaaa aatcttacgg ataaaaaaga
    47761 gaaaaaacta aatttgaaaa gtagagcagc tgatcttttt ggtcgctaca gcatggtgat
    47821 cattttagcg ggactactta ttgcgtttca attgatgacg gatggtattt tctggcgtcc
    47881 attgaatata actaaccttg ttctgcaaaa tagccatata ttagtactag ctgcagggat
    47941 gttattagtt gtgctcttag gtcatgtgga tttgtcggta gggtcagtga tggcgtttgt
    48001 tggtgcaatt gcgggcatga tgatggtcaa tcgccaaatg aacccgtgga tgacagttat
    48061 cgcatgtctt gcagtaggcg ggctgatcgg cgcatggcaa ggtttttggg tagcttatgc
    48121 agggataccg gcgtttatcg tgactttagc aggattgctg atgtttcgtg gactgacaca
    48181 agttgttcta ggaggccaat ctctagcacc ttttccagct gttttccaaa aaatgtctac
    48241 gggttattta ccagacttaa gcgaaggaag cagccttcac ttcttgacat tgattttagg
    48301 aatgatcatc acgatcgtgt tagttgttgg tcaatggcga acaagaaatc gtcggaaaaa
    48361 tcatttattt gaagtggaat ctccaacagc tttcttggta aaggcggtat ttacagcagt
    48421 cgttgtacta ggaataactt atatctttgc ctcttatcaa gggtatccga ttattttgat
    48481 cattcttggt ttgatcgttg cagcatatgg gtttttgaca aataaaacag tagcaggtcg
    48541 acagatttat gcgacgggcg gaaatcgaaa agcggctgaa ctatcaggga tcaaaacaaa
    48601 gcgaatcacg ttctgggtat tcgtcaacat gggagtcatg gcagctttag ctggattagt
    48661 tttagctgct cgattgaatg cggcaacacc tcaagcaggt acatcgatgg aactggatgc
    48721 aatggcggca gtatattttg gtggtgcttc gacttccggc ggcattggaa caatcatggg
    48781 tgcgattgtc ggtggcttgg tcatgggtgt attgaacaat ggcatgtcga ttttaggcgt
    48841 cggggtagac tggcagcagg caatcaaagg attgatcttg cttttagccg ttgtgctaga
    48901 cttgtataat aagaaaaaac gaacaacgta ggagaacgcc ggttattcag aaaaaagact
    48961 gtgacaagac atttgtcaca gtcttttttt cgctaaaagc gaacattcat tgtttcgttt
    49021 gtatagacta aaaataatat atgttttttt accattcgta taaattctct ttttgctctt
    49081 gatttttttg cttaattgag ttaaattaca tagggcgcta aaaaaagcct tgattaaatt
    49141 aataatgttc gtgttttgct ggatgtgaac atcaggagga taatgtaatg aaagtatttg
    49201 attacgaaga tattcaatta attcctaata aatgtatcgt aaatagccgt tctgaatgtg
    49261 atacaacggt cacattaggt aaacatacat tcaaaatgcc agtagtgcct gccaacatgc
    49321 agacgattat tgatgaaaca atcgcagaat tcttagcgga aaatggttat ttctatatca
    49381 tgcatcggtt tgatgaagca gctcgaattc cgtttatcaa aaaaatgaaa aagcgtggat
    49441 tgattacctc gatcagtgtt ggcgtcaaga aagaggaata ttcctttata gagaagttgg
    49501 cagaagaatc gctaaatcct gattatatca ctatcgacat cgcgcatgga catgctaact
    49561 cagttattga tatgattcag catattaaaa aatatttgcc tgaaactttt gtgattgccg
    49621 gtaatgttgg tacaccggaa gccgtccgtg aattggaaaa tgcgggcgca gatgcaacaa
    49681 aagtcgggat tggtccagga aaagtatgta ttacaaaaat caagacaggc tttgggactg
    49741 gaggctggca actggcagct cttagatggt gtgcgaaagc agctcgcaag ccgatcatcg
    49801 ctgacggtgg gatcagaaca catggcgata ttgcaaaatc tgtccgtttt ggtgcgacaa
    49861 tggtcatgat tggttcattg tttgccggtc acgaggaatc tcctggcgaa acaaaagtcg
    49921 aaaatggaat cgtgtataaa gaatactttg gttctgcttc agaattccaa aaaggcgaaa
    49981 aacgaaatgt tgaaggaaag aaaatctgga tccaacacaa aggatctttg aaagatacac
    50041 tagtggaaat gcaacaagac cttcaatcat ctatttctta tgctggagga agagatctgg
    50101 aagccattcg aaaagttgac tatgtcatcg tgaaaaattc gatttttaat ggagacacaa
    50161 tctaaaaaat aaataaaata ttaggatgtt gtgaaaaagt tgtcctgcat taagtaataa
    50221 gaacagccaa acaaaaatag ttctttatat gttttgtttg gctggaatta ttatcgcaga
    50281 tacaagcttt tgaacatcat tattcagaat aagggactgt gataagattt ttgtcacagt
    50341 cccttatgtt ttgcaaaaaa agtttttctt ttttctcgta aattcggtaa aatcaaaaaa
    50401 aaaaatagac aatagaaaag agaagcttat gtgggaaaaa gtagagaaaa aacaaggacc
    50461 gatttatcgt caaattatgg aacagattat gagagaaatc gaaaacggaa ggatcaatcc
    50521 tggaagtcaa cttgaatcag aacgaaaact agggcaactt tttggtgtga atcgttccac
    50581 cgttgtccat gcattggaag agcttaggga gcttggggta ctaacgagca aacgtggcag
    50641 cggatggttt gttaatcaga ctgaatgggg gaaattcgct gttccaagaa tcgattggcg
    50701 gcaaatgatc tctcctcgtt atgagcagac ggactggtat gagcaaaaaa taagagaagc
    50761 aaagcagatc caaaaaacat cgtttcttga tttatacgct agcgagatgc cagatgagct
    50821 tttgccgaat tttgagtttc cttcttattc tcttgaagaa atcttagcgg aagaaaaaga
    50881 aatggatctt ttaggctata ctccgttacg taacaaaatc aaacggtatt tggaaagtaa
    50941 atttgaattg gcattttccc ccaaccagct tcttgtgact ggtggcggtc agcaagcaat
    51001 ctttttgatt ttacaaacga ttctttcagc tggagagggg atagctgtag agtcaccttc
    51061 ttttttttac cgattacctc ttttcaaagc ttcaggaacg cgtttatttg ggataccgat
    51121 ggatgaagaa gggatcgact tagaaaaact gaaagaatcg atccataaaa ataaattgaa
    51181 agcagtgctt atcaacccga attttcaaaa ccctacagga aaagtgatga gtcaaaaacg
    51241 acgagaaaag ctagtagaat tgtgtcgaca gtatcggctt ccaattattg aagacgatgt
    51301 atttacggat ctttcatttc taaaccaaga agaagtcctt cctatacgaa cgattgatcc
    51361 ggataatgtg ttatacgtcg gttcgttatc tagggtttta ggaaaaacaa cgaaaatcgg
    51421 ttgggtgata ggacctgaga cttttatctc gcaactagct caagcgcaag aaatgatgga
    51481 gttttcgatg aatatcctta cacaaatcac agtggctaat gtatttaatg aagcaattga
    51541 tttgaaaatg caagatgtaa gaaaaaagtt gaaagaaaaa agccgactga taagcgcttg
    51601 gggagattca caatcgtttt tcaagcttca ttcaatttta ggtggttact atgcctggat
    51661 tacttgggat gggaaaaaac tagaccccga actagcagaa aaagtagtag atatgggtct
    51721 tggaattgca ccaagtctac tttttgggca agatataaat ggaatcagaa tcaattacag
    51781 taggctggat gaaaaccaaa taccgttgtt ttattcaaag atgaaaattc tagaaaagtg
    51841 gttaacagaa taatttcaca aagtaaatag attaaagaat ataacagctt ggatttaaat
    51901 ttcaagctgt ttcttttttt tcggaaaaag aatacgatat aaagaaacta agaaaaaacc
    51961 attatttgta cgtccgttca cgatgtgtaa ataaaataaa tgtttgcaac aaaactgtat
    52021 aacaccaacg tttttaaata gaaacagatg gttgtaagtt tgattagaaa atagaaaaaa
    52081 tgcagatgaa atataaaacg ctttccttat tgtgatttta ttcactaatg ctgttaatat
    52141 gcggattggc ataatttcct ttcatcgtga aaatttgtgc ttttagcttg tatttctcat
    52201 aaatccatga taatttatta atgaagacgg ttaaatagtg atacagtttt attcactgtt
    52261 tcaatcgcag aatgaagaga ttttcttata gatgagagag gaatgtgtga caaatggcaa
    52321 acaaaaaagc accgatcgac ttccaagcac tgctagatga agtcaatgca gatttcccag
    52381 tatatcaagc acttgatcaa gatggaaacg tagttaacaa agatttagta cctgatttat
    52441 ccgatgatga actcgttgaa ttaatgactc atatggtatg gtctcgtgta ttagaccaac
    52501 gttcaacagc gctgaaccgc caaggacgcc taggcttttt tgcaccaact gctggacaag
    52561 aggcaagtca gctggctagt gcttacgcat ttgataaaga agatgttctt cttccaggtt
    52621 atcgggatgt acctcaacta gtaaaacatg gtttaccttt atctcaagct tttttatggt
    52681 ctcgaggaca tgctgcaggt aattcttatc cggaagaatt gaaagctcta ccaccacaaa
    52741 ttatcatcgg tgcacaatat gtacaagcag ccggtgttgc attaggtttg aagaaacgaa
    52801 acaagaaaaa tgtcgtcttc acttatactg gtgatggcgg ttcatcacaa ggtgattttt
    52861 acgaagcaat caatttcgct ggcgcttacc atgcaaatgc cgtattttat atccaaaaca
    52921 acgggtatgc gatctctaca cctcgtgaaa aacaaactgc agcaaaaaca cttgcacaaa
    52981 aagctgtcgc agctgggatt cctggtattc aagtcgatgg aatggatccg cttgcagtat
    53041 atactgtatc taaaatggca cgggaatggg cgatcagtgg aaatggacca gtcctaatcg
    53101 aaacactgac ttatcgttat ggaccacata cactatctgg tgacgatcca acccgctacc
    53161 gtacaaaaga cacagatgac gattggcaga aaaaagatcc attgatccgc ttccgtaaat
    53221 atttgacgga aaaaggactt tggtctgaag aaaaagaaga acaagtcatc gaagcaacta
    53281 aagaagaaat caaagcagct attgctgaag ccgacaaagt accaaaacaa aaggtttcag
    53341 atttcttgaa aaacatgttc gaagtatctc cacaatcaat caaagaacaa attgcaattt
    53401 atgaagcgaa ggagtcgaaa taatcatggc acaaaaaaca atgatccaag caatcacaga
    53461 tgccttagca cttgaactag aaaatgacga gaatgtcgtt gtttttggtg aagatgttgg
    53521 gaaaaacgga ggagttttcc gggcaactga aggattgcag gaaaagttcg gagaagaccg
    53581 agtattcgat actcctttag ctgaatctgg aatcgcagga ttgagtttcg gtcttgcgtt
    53641 agaaggattt cgtccagttc ctgaaatcca attctttggt tttattttcg aagcaatgga
    53701 cgaagtagta gctcaaatgg ctcgtacaag atatcgaatg agcggcacta gaaatctacc
    53761 catcacaatt cgttcgccat ttggtggcgg tgttcataca ccagaattgc attcggataa
    53821 tttagaaggt ttgatcgctc agtctcctgg tattcgagta gtgattcctt ccaaccctta
    53881 tgatgcaaaa ggactattga tttcttctat tagaagtaac gatccggttg ttttcctaga
    53941 acacatgaaa ctatatcgct cattccgaga agaagtgccg gatgaagctt acgaagttcc
    54001 tttggataaa gcagcagtta ctcgtgaggg aacagatgta tctattatca catacggagc
    54061 aatggtgcgt gaagcaatca aagcagcaga caatcttgca aaagaaaata tatctgttga
    54121 aatcattgat cttcgtacag ttgcgccatt agatgtagaa acgatcattc aatccgtgga
    54181 aaaaactggt cgcgtagttg ttgtccaaga agcacaacga caagcgggcg ttgccgcgca
    54241 agtagtttct gagatctcag aacgcgctat cctttcatta gaagccccaa tcggacgagt
    54301 ttctgcacct gatacagtct tcccatttgg acaagcagaa aatgtctggt tgccaaatgc
    54361 aaaagatatc gaagacaaag taaaagaaat cgcggaattt taagaaaaga agggacgaaa
    54421 caaagtcatg gcttatcaat ttaaattgcc ggatatcggt gaaggaatcg cagaaggtga
    54481 aatcgtcaaa tggttcgtca aaccaggaga tacgatcaat gaagatgata cattactaga
    54541 agttcaaaat gacaaatcag tagaagaaat cccgtcacct gttacaggaa cggttaaaaa
    54601 tgtgattgtt ccagaaggta ccgtagcaaa tgttggggat gtattagtag aaatcgatgc
    54661 accaggacac gaagacaatg aaggggacag tggtgtagcc gcagaatccc aaactccagc
    54721 taaaccggct gctgaaccca ctgttgatac agaatcagct ggatcgtcaa gcgaaggagt
    54781 cttccaattt aagttaccgg atatcggtga aggaatcgca gaaggtgaaa tcgtcaaatg
    54841 gttcgtcaaa ccaggagata cgatcaatga agatgataca ttactagaag ttcaaaatga
    54901 caaatcagta gaagaaattc cgtcacctgt cacagggaca gttaaaaacg tgattgttcc
    54961 agaaggcact gtagcaaatg ttggggatgt attagtagaa atcgatgctc ctggacacaa
    55021 tagtgcaccg tcaactagtg cgccatcagc tgaagcacca aaagaaaaag tggaaacatc
    55081 aggttcagca agtgtcgttg aagctgccga tccaaataaa cgtgtattgg ctatgccatc
    55141 tgttcgtcaa tttgcccgtg aaaaagatgt agatatctca caagtaactg caactggaaa
    55201 aggtggcaga gtaacaaaag aggacatcga aaacttcttg gcaggtggtc caagcagtgc
    55261 accagcgaaa tcagaagcgc cagaagcggc agcaccgaaa gaagcagctc ctgcagcaga
    55321 aagcaaacca gctgcaccag caaaaccatt caagtccaac ttaggagact tggaagaacg
    55381 tgtagcaatg acgccaacac gtaaagctat cgctaaagca atggtcaaca gtaagcatac
    55441 agctccacac gtgacattgc atgatgaagt agaagtgtct aaactatggg ataatcggaa
    55501 acgatttaaa gaagttgctg ctgcaaatgg tacgaaactt actttcttgc catatgtcgt
    55561 gaaagcttta acagcgactg ttaagaaata cccagtattg aatgcatcta tcgacgatgc
    55621 aaaccaagaa atcgtttata aacattacta caatatcggt attgcaactg atacggatca
    55681 cggactatat gtaccaaatg tgaaagatgc agaccgcaaa ggaatgtttg ctattgcaga
    55741 cgaaatcaat gagaaagcaa aattagctca tgacggcaaa ctatctgcag aagatatgcg
    55801 caatggaaca attacgatca gcaatatcgg atctgtaggt ggcggttggt ttacaccagt
    55861 catcaactat ccagaagtag ctattttagg tgtaggaacg attgcacaac aaccaatcgt
    55921 aaatgctgaa ggcgaaatcg ttgtcggtcg tgtgatgaaa ctgtcattaa gtttcgatca
    55981 ccgtatcgta gatggagcaa ctgcgcaaca agcaatgaat aatatcaaac gtcttttagc
    56041 tgatccagag ctattaatga tggaaggatg ataaacaaat ggtagttgga gattttgctg
    56101 tagaattaga tacagttgta attggtgcgg gacctggtgg ctatgtagct gccatccgcg
    56161 ctgctgaaat gggacaaaaa gtagcaatca ttgaaagaga gtatattggc ggtgtttgtt
    56221 tgaatgtcgg ctgtattcct tcaaaagcac tgatagctgc aggacaccat tatcaagagt
    56281 cactagattc tgaaatgttt ggagtaacta gtgaaaacgt caaactagat tttgcaaaaa
    56341 cacaagaatg gaaagaaaac aaagttgtcc atacgttgac ttctggtgtt ggtttcctat
    56401 taaaaaaaca taaggttgaa acaatcgaag gagaagcgtt cttcgtagat gatcacacac
    56461 tacgcgtcat tcatccagat tcagctcaaa cttattcgtt caataacgca atcatcgcaa
    56521 caggttcccg tccaatcgag attccaggat ttaaattcgg aggacgtgtg ttagattcta
    56581 ctggcggatt agcattgaaa gaagtaccta agaaatttgt gatcatcggt ggcggtgtga
    56641 ttggtgccga attgggcgga gcgtacgcaa acttaggagc agaagtaacg attcttgaag
    56701 gctcaccaca aattttacca acttacgaaa aagatctagt aaaattagta gaagatgatt
    56761 tcaagaaaaa aggcgtaaca gtcgtaacga atgcaatggc gaaagaagca gtcgataacg
    56821 gtgacagcgt gacagtgaaa tatgcagtgg acgggaaaga agaatccgtt actgctgatt
    56881 atgtgatggt cactgtaggt cgtcgtccga atacagatga tatgggctta gaacaagcgg
    56941 gtgtcgaagt aggagaacga ggattgatca cggtggataa acaaggacgt acgaacgtac
    57001 ctaacatcta tgccatcggt gatatcgttc caggggcggc attagcacac aaagccagtt
    57061 atgaagcaaa aatcgctgct gaagcaatct ctggcaaaaa agtagctgta gattataaag
    57121 caatgccggc agtagccttc actgatcctg aattggcttc tgtaggtatg acgatcaaag
    57181 aagcaaaaga tgctggtatc gaagcaaaag catataaatt cccattttca gggaacggtc
    57241 gggcattatc gcttggtaaa acagaaggat tcatccgtct agttacgacg atcgaagata
    57301 acgtgcttat tggcgcgcaa atcggtggag tcggcgcaag tgatatggtc tctgaattag
    57361 ctttagcaat cgaatcagga atgaatgctg aagatatcgc cttgacgatt catcctcatc
    57421 catctcttgg cgaaatcgtc atggatgctt cggaattagc attaggttta ccaatccata
    57481 tttgatttga ataatacagg cgaaacgcaa ctgaaaaatc agttgcgttt tgttttttag
    57541 aattatcaat aatattatta tgtaaactta aaaatatgac aacttcttgg tttattacca
    57601 cttcctatgc tacactgaag aggaatatga aataggagag ttgaagatgc aagaatatca
    57661 gtatccactt gatttagatt ggacaacaga cgaaatggtc attgtaatga agatgtggga
    57721 agatctggaa cgtgcgaatg aaaaagggat aaacaatgaa gcttttttga agacttatca
    57781 gcagtttaaa actgttgtca aatccattgg tgaggaaaaa cgattgggac gggaatttga
    57841 aaaagcttcc ggttattctt tatatcgtac agtgcagcaa gcaaaaaaaa atccaaacaa
    57901 aactttgaga atgaacgggt gagataaatg gaacagatga ttgatcatat caagtcctgg
    57961 cttgaagaag ctggtgagaa aatcaaatct tctcaacaaa cattaacaat ctcgcaaaaa
    58021 tcaaatcgaa cggatctagt aacaaatgtc gatcgaaaca tccagaattt tctaatcgaa
    58081 aaaatccatt cctttgatcc agaggcgaaa atattggcag aagaagaagg gtgtaatcaa
    58141 ttatcggatc tcgatggaag agtctttatc atcgatccta ttgatggcac cttgaatttt
    58201 gtgattgaag gggaaaattt ttgtattatg ctcgctgttt atgaatccgg cgttggaaag
    58261 cttggtttca tttatgacgt gatgagaaat gaactttttt ggggtggaaa aggaataggc
    58321 gtgtataaaa atgatgagcc attgcctaga ccagcaaata aatccttatc ggaaggctta
    58381 cttggtgtga atagttatct tttcggtcat aataaatatg gaatccgaga aattgcggaa
    58441 agcagcatgg ggacacgtat gtacggatgc gctggtcttg aactagtggc aatcttgaaa
    58501 ggaaaccaca ttgcttatat ttcaaacctt agcccttggg attatgcagc gggaaatgtc
    58561 ttattggaag agtttggtat ggtaacaagc ggtctttttg gtactccttt gacatttgaa
    58621 aaaagggaat actatttagc agggacttct tgtgcatatg cagaaatcgc agaccttttg
    58681 aaaaaagaag gctgaaaaaa aggtagaaat cattcacaaa aatgataaaa acgagcaaaa
    58741 gattaatttt ctcgaaaaaa tgaaaacatt ttactatatt tcatgaaaaa agtctgctat
    58801 aattagcagt cgagtaaaat ttgccctgtc ataaagaacc aataaaaaag gagttagtta
    58861 cattgaatta tagaaacgat atccgtaacg tcgcaattat tgcccacgtt gaccacggaa
    58921 aaacaacatt agttgatgaa ctattaaaac aatcagatac attagacgca catacgcaat
    58981 tgcaagaacg tgcgatggac tcaaatgcgc tagaaaaaga acgtggtatc acgattttag
    59041 ccaaaaacac agctgtagac tataaaggta ttcgcgtaaa catcatggat actccaggac
    59101 acgcggactt cggtggcgaa gtagaacgga tcatgaaaat ggttgacggc gttgtgttgg
    59161 tcgtagatgc gtatgaagga acaatgcctc aaacacgttt tgtattgaaa aaagcactgg
    59221 aacaacatat cacaccaatc gttgtcgtaa acaagattga caaaccttct gctcgtcctg
    59281 agcatgtcgt agatgaagtt cttgaactat tcatcgaatt aggagcagat gatgatcagt
    59341 tagactttcc tgtgatttat gcatctgcac taaatggtac gtcaagcttg tcagatgatc
    59401 cagcagatca agaaccaacc atggcaccta tttttgatac aattattgaa aaaatccctg
    59461 ctcctgtcga taacagcgac gaaccattac aattccaagt ttcattactt gactacaacg
    59521 attatgtagg tcgtatcgga atcggacgtg tatttagagg aacaatcaaa gtaggagacc
    59581 aagtagcatt aattaaatta gacggaacag ttaagaaatt ccgtgtaacg aaattatttg
    59641 gtttctttgg actaaaacgt ctagagattc aagaagcaaa agctggagac ttgattgctg
    59701 tctcaggtat ggaagatatc tttgtcggtg aaacagttac tcctgtggat catcaagatg
    59761 cgttacctat ccttcacatt gacgaaccaa cattgcaaat gactttctta gttaataatt
    59821 caccatttgc cggtcgagaa ggtaaattcg taaccgctcg taagattgaa gaacgtttga
    59881 tggcagaact tcaaacagat gtatccttac gagttgaacc aacaaactct ccagatgcat
    59941 ggacagtttc tggtcgtgga gaattgcatt tgtctatctt gattgaaaac atgcgccgtg
    60001 agggatacga attgcaagta tctcgtccag aagttattga aaaagaaatc gacggtgtaa
    60061 aatgcgaacc gtttgaacgc gtgcaaatcg atacaccaga agaatatatg ggtagtgtta
    60121 tcgagtcctt gagcttacgt aaaggtgaaa tgcaagatat ggtccataca ggaaacggac
    60181 aaatccgttt gacattctta acacctgccc gcggtttgat tggttattca actgaattcc
    60241 tttcaatgac acgtggttac ggaatcatga accatacttt tgaccaatat ctgccaatgc
    60301 ttcctggtca aattggcgga cgtcaccaag gggcgcttgt ttcgatcgat acaggaaaag
    60361 caacgactta ttctatcatg agtatcgaag aacgcggtac agtcttcgta gaaccaggta
    60421 cagaagtata tgaaggaatg attatcgggg aaaacagccg tgataatgat ttgactgtca
    60481 acatcacgaa agcaaaacaa atgacaaacg tacggtctgc tactaaagac caaacatctg
    60541 tcatcaaaaa accaaaacaa ttgacgttgg aagaatcttt ggaattcttg aatgatgatg
    60601 aatattgcga agtaacacca gaaagcattc gcttgagaaa acaaatttta gagaaaaatg
    60661 ctcgtgaaaa agcatctaaa aagaaaaaat aatctgtaaa aggatgaaga gagaaaccag
    60721 cttgttataa aaaatagctg gtttcttttt ttgtccaact cttttctgtg gagaagtcat
    60781 ctttgtcaat ggacataaat tcagaaaata cgccgaaaga cgtttaaaag acttttaaaa
    60841 aacttatttc tagagagttt ttgtttcata ataagataat gtttcacgaa aggagatcaa
    60901 cttgtccttc gaagaaaatc gaagtaaaat ggcaagagaa aggagcggga agatgaacga
    60961 cttattaaaa caatactttg gctatgatga gtttagacct ggtcaaaaag aaattatcca
    61021 gaaagtcatt gatcaggaaa atgtattagg aatcatgcct accggaagtg ggaaatcaat
    61081 ctgttaccag cttccagctt tactattaga tgggcttact gtggttgtgt cccctttaat
    61141 ctctttgatg aaggatcagg tggacgcggc gaatcaatta ggtatacccg ccacttttat
    61201 caatagctcg ttagatggtt acgaaacagc tagacgcttc caagaaatcg atagacagca
    61261 gtaccgttta ctttatatcg ctcctgaacg ttttatcatg ccggatttta tccaagcaat
    61321 gaagcgatgg aacgtccgta tgatcgctat tgacgaggca cattgtatct ctcagtgggg
    61381 gcatgatttc cgcccaagtt atttacagat ggcgaaccag ctagatcaac tgccaaatcg
    61441 tcctgtaatt gttgctttga cagctacagc gactgtgcaa gtagctgctg acataaaaag
    61501 acttttaaaa attccagaaa acaaccatat tcagactggt tttgaacgag aaaatctacg
    61561 atttcaagta attaaagatc aaaaaaaaga acaatatcta atcgaatatt taaagatcaa
    61621 caaaaatcaa tctggtatca tttatgcagc aacgagaaaa gaagtagacc gtctctatca
    61681 tttgcttaaa aaattcgatt tttccgtggg tagatatcat ggtggtctaa atgagaatga
    61741 gcgaacagaa atgcaagaag cctttttata cgatcgcttg cagctgattg tagcgacaaa
    61801 tgcatttggt atgggtataa ataaaagcaa tgtccgtttt gttatccatt atcaaattcc
    61861 tggctctcta gaagcatact atcaggaagc tggtcgggcg ggaagagatg gtctttccag
    61921 tgaagccatc ctgcttttct ctcctcaaga tatccaagtc caaaagtttt ttatccagca
    61981 gtcccaaaga gaagaagggc aaaagcaaaa agaatatgaa aaattaaaag cgatgacaga
    62041 atacgtgtat attgagtcct gtcttcagca atacatccta aactattttg gcgagacaag
    62101 cagtccgtgc aaccgttgtg gtaactgttt agatgacaga gaaatagtag aagtaacgac
    62161 agaagcacag atggttcttt cttgcttaaa acgtatgggt gagaactatg gtaaacaaat
    62221 gctgatgaaa gtcttagcag gatcgaaaga acaaaagctg caagctttag gttttggaca
    62281 tttatctacc tatggactga tgaaaaacca atcgcaaaaa gaaacgatgc agttaattga
    62341 atatttgata tcgaatggct atcttctgac catcaatggt gagtatcctg ttttgaaagt
    62401 aacagaaaga gggatacaag tattgaaagg acaagaatct gtttatcgaa aggaacccaa
    62461 gaaagtccag cagctatcgg atgaagaaac cgatacacta tttgaagtgc tgcgggaact
    62521 gcgaacggat ctagcatcag aagcaggcgt tcccccgtat gtcgtatttt cagattccac
    62581 attgaaagaa atgagccgaa tacgtccatc aagcagattg gagatgcttc agataaaagg
    62641 agttggccaa agcaagcttg ataaatatgg cgaagccttt ttatctcgga taaaaaatgc
    62701 ggactctaac gttctggata agtagaaaga acgaatacgt aaaaatgaat aaaaacaact
    62761 ggttaaatct gttttttttg ctccttatga aaatcaaata tgttataatt aaggaattag
    62821 aatgggaggt aagcacagat ggattctttg tcgaaaaaac ttgcgatcca agtattaaat
    62881 gatgaagcag aacggatcaa acgattaatc cgaaatcaaa acaacagtct ctgtatctca
    62941 caatgcaaag ccttcgaaga agtggtagat acacagatgt acggcttttc ccggcaagtc
    63001 ggttttgctg tccgtatagg agtaatcgga aagaacgagg gccagctgat gttaagtgag
    63061 ctagaacgag aattgaatca gttatatagt gaggtttacc aagaaattta tgataaaaaa
    63121 gaagttggca aggaggaata gacttgccta agaaagtgaa aaaaaggcat ctattagact
    63181 atagcatctt gattccctat ttaattttat gtgtattggg attgatcatg gtatatagtt
    63241 ctacgtcgta tctattatta gaaaacggac aaaatccgtc cgcatcagtc attaaccaga
    63301 gtattttttg ggtgcttagc ttgattgcta tcgcactact ttataaaatg aaaacagatg
    63361 ttttgaaaaa ccagcgtttg atcatggcag ccatcgcagt tttgacgatt ttgctgctga
    63421 ttgttgtgtt ttttggtaag gagatcaatg gggcgaaagg ttggctgcaa attgcaggat
    63481 tctcgatcca acctgccgaa tacctaaaaa tcatttctat ctggtacctg tctctgactt
    63541 tatctaaaag acaaaacagt gtacaaaaag attttcttgg gactgtgaaa cgtccacttg
    63601 caatggttat cggacttact gcattagtcg ctattcttcc cgattttggt aatgcggcag
    63661 ttatcttttt gattattttg gttctgcttt tagccagcgg agtcaattat gtgtatactt
    63721 tgattgtagg agtaggaggc ttttgtctaa gtacttttac gatctggctg atcaatatca
    63781 caaacggaaa gatcttaccc ggacgtttac agtatatcta taatcgattt gctatttacc
    63841 aaaatccttt ctcagacgaa ttaaataaag ggcatcaact agtcaacggc tactatgcca
    63901 tgttcaacgg aggactattt ggcaggggat taggtaacag tatccagaaa aaaggatttt
    63961 tacaagaagc acaaaccgat tttatttatg caatcgtagt ggaagaactg ggagtgatta
    64021 tggggatttt gatattagcg ttgctattct ttatgattgt gcgcattgtc cttgtaggta
    64081 tccgttcaaa agatccgttc aattcgcttt tgtgcattgg gatcggcgca atgtttttga
    64141 tccaagtatt tgtcaatctt ggaggaatta ctggcgttat tcctttgaca gggatcacgt
    64201 tcccattttt aagtcaagga ggctccagtt tgctgatgct ttcgatttgt gtcggctttg
    64261 tcctcaacat cagtgcggat gaaaaacgca agagcttagg tttataataa aaaaagatgt
    64321 aggagtggtt cgatgaaaaa agttttagtt gctaacaggg gtgaaatcgc tgtacgtgta
    64381 tttcgtgctt gtacagaatt aggaattaaa actgttggaa tctatgcaga agaagatgaa
    64441 tattccgtac accgtttcaa agcggatgaa gcatatttag taggacaagg aaaaaaaccg
    64501 attgatgcgt atctagatat tgaagggatc atttctatcg cgaaagaatg cggagctgac
    64561 gctattcatc cgggttacgg tcttttgtcg gaaaacttga attttgcgca acggtgcgaa
    64621 gaagaaggca tcatttttgt tggacccaaa ctgcatcatt tagatatttt tggagataaa
    64681 atcaaagcaa aagctgcagc tatcgaagcg gggattgctt cgattccagg cacagatgga
    64741 ccaatcgctt ctatagacga tgccttggag tttgcgaaac aatacggtta tccgattatg
    64801 atcaaggcag ctctaggcgg cggcggacgc ggcatgcgtg tagctcacga tgaaaagagt
    64861 gcaagagagg gctacgaacg tgcgaaaagc gaagcaaaag cagcctttgg tagtgatgaa
    64921 gtgtatgttg aaaaatacat cgctaatcct aagcatatcg aagtacagat tctcggggat
    64981 acgcatggaa acgtcatcca tctttttgaa agagattgtt ctgttcagcg ccgtcaccaa
    65041 aaagtagtag aagtagcgcc ttgtgtctct atgaatgaac agcaacgtca aaaaatctgc
    65101 caggcagctg tccaattgat gaaatatgtc gggtatgtca acgcaggtac agtagaattt
    65161 cttgttgaag gagatgattt ttactttatc gaagtcaacc ctcgcgtcca agtggaacat
    65221 acgatcacag aaatgattac agatattgat atcgtaacaa cgcaactgtt gattgctcaa
    65281 ggtttggatc tgcataaaga aatcggattg cctcagcaag aaggaattaa attaaatggt
    65341 tcagccattc aatgccgaat cactacagaa gacccgttga ataacttttt accagacaca
    65401 gggaaaatcg atacgtatcg ttcacctggt ggttttggcg tacgtctgga tgtcggaaat
    65461 gcttacgcgg gctatgtagt gacaccgtat tttgattcat tgctagtaaa agtatgtacg
    65521 catggtgcta cctttgaaac agccattcag aaaatggaac gttgcttgaa agaatttaga
    65581 atccgtggag tgaaaacaaa cattccattt atgctcaatg tcatcacaca tcctgaattc
    65641 caatcaggaa atgcaaaaac aaccttcatt gatagtacag caacattatt tgaatttcct
    65701 cgactacgag accgcggaaa caaaacgatg aaatatatcg gtgaaattac tgtgaatggt
    65761 tttccaggta tcgaaagtgg cgaaaaacca ttttatgaag aaccacgtat gcctaaagat
    65821 ctaatcacaa gaactgatta cgtaacggct aagaatgtat tagatgcgaa gggtgccgat
    65881 gctttggtcg aatggatcaa aggacaggaa aatttgttgt tgacggatac gacatttaga
    65941 gacgcccatc aaagtctgct agcaactcgt gttcggacaa aggatttcaa gcagattgca
    66001 cgtttgactg gagaaggtct tcctgaactc ttttcaagtg agatgtgggg gggagcaaca
    66061 tttgatgtgg cttaccgctt tttgaatgaa gatccttggc aacggttgag aaaaattcgt
    66121 tctttaatgc ctaatacgtt gctgcaaatg cttttcagag gttcaaatgc cgttgggtat
    66181 tctaattatc ctgacaatgt attggtggaa tttgtcaaag aagcagcagc gcaaggaatc
    66241 gatgtatttc gaatctttga tagtttgaac tggactccac aaatggaaaa aagtatccaa
    66301 gctgtacggg atactggtaa aatcgcagag gcagctattt gctatactgg cgatatcaac
    66361 gatccaagtc gggcaaaata caatgttcag tattataaag acatggcaaa ggaactagaa
    66421 caactgggtg cgcatatcat tgcaatcaaa gatatggctg ggctgcttaa accgcaggca
    66481 gcttatcgtt tgattagtga attgaaagaa acgacagatc tgccaatcca tctgcatact
    66541 catgatacca gcgggaatgg aatcatcact tattctgctg cttcaaaagc aggagtagac
    66601 atcgttgacg tggcaatgag tgcaatgagt gggaatacta gtcagcctag catgagcagc
    66661 ttgtattatg cactggtcaa tggtccacgg ctgccagaaa tcacgattga aaatgcacag
    66721 aaattaaacc attattggga agatgtgcgc atgtattaca aaccgtttga aaacggcttg
    66781 aatgctcctg aaacagaagt atatatgcat gaaatgccag gaggacagta ttcgaatcta
    66841 cagcaacagg caaaagctgt cggattaggt catcgctggg atgaaatcaa acaaatgtat
    66901 catactgtca acttgatgtt tggcgatatc gttaaagtaa ctccatcatc taaagtagtt
    66961 ggagatatgg cactatttat ggtccaaaat gatcttacag aagaagatat ttatgaaaaa
    67021 ggcgaaacac taagtttccc tgaatctgtt gtgactttct tccaaggaga actagggcaa
    67081 cccgttggcg gatttcctaa aaaattgcaa aagattattc ttaaaggcag acctgcattg
    67141 aatgaacgtc caggtctttt ggctgaatca gtcgacttca acgaagtaaa aaaagaattg
    67201 gcagaaaaaa ttggctatga accaaaacaa gacgaagtat taagctattt gatgtatccg
    67261 caagtctttt tggactatca aaaagcatat aatcaatttg gcgatgttac attactggac
    67321 acaccaacat ttttccaagg tatacgtttg ggtgaaacaa tcaatgtaca aatcgaacgc
    67381 ggaaaaacgc ttatcattcg tttagatgaa atcggagaac ccgatatcga agggaatcgc
    67441 gtactgttct tcaatttgaa tggacaaaga cgtgaaatca ctatcaaaga taattcgatc
    67501 atcagtacgg tccaaacccg attgaaagct gaaccgacaa accgagaaca aattggagca
    67561 acgatgtctg gttctgtttt ggatgtatta gtgaaaaaag gcgataacgt taaaaaaggt
    67621 gatacgttga tgattactga agcgatgaaa atggaaacgg ccatcgaagc acgttttgac
    67681 ggagaagtcg cacatgtata tgtgtcttca ggagacacta tttcgtctgg tgaccttttg
    67741 attgaagtga ctgagaaata ataagcgaaa ggtggggaaa catgaaaaga ctgggtttgt
    67801 tttggctgat tctgctatta gttattgtgg cattctacat ggaaccagtc ttgtttccgc
    67861 caaaacttga agtgaaggaa aactctgatc aacaaatatc aaaccaaatg acaacgtgga
    67921 aataccagga gcttaaagca actggttttt ctacttatat cggaaaaccg atcgatcagc
    67981 tggaaaagga ttttggccaa gcctatgatc gattaactag cggatttggt tttgaaacaa
    68041 gatattatga aaataaagct agtcatctca catttgaagc gaacatccaa gacagcagag
    68101 tcacaactgt taaagtactg caaacagggc ctgctgatat cgcgccgttt tatttaggga
    68161 tgacgatgca agatcttacg aaaatcacta ctatctatac taatttcact tttgagtacc
    68221 atgatacaga agttggaatc gaactaatgg aagaggatat gaattatcgt ccgctaattg
    68281 cttttgataa cgacactttt gctattttat tttttgatca aacaacaaac ggcctatttt
    68341 cagttgtgta tttagataaa gatagtcttt tgaaactatt gccatatcaa gtgtttggtg
    68401 aaggccttcc acattatcaa gcagataaat cggctgattg ggaatcaatc aatcgcgtta
    68461 aagaacgaaa aagtacgact ttattaaata tgcttagaag agaagacgaa cttcccatat
    68521 acaatcaaac acttgccttt caaaaccaca gtcagctgct actacatgat tttttgacaa
    68581 ggcctgagga aatattgtca gaggaacgta tggctgattg gcaaaaatcg ctaggcagtg
    68641 ctcaaacgac agtgaaattc tcactgacga atgatgaatt ggagaagtta atcagtaaac
    68701 aaaaattaga aaatactagt gggctattta ttcatccggc gattgacgct actttttcgt
    68761 ttttatattg gtacagcgat ccttacaacc atgaccgttt catggacccg ggaacggatt
    68821 ctgtaggcat tgctttttct aaagaaaata tgttagtctt attgcaagaa gaaaacggag
    68881 aaagtagtga tagcagtgat cgttaacgaa gagctgtttc aactggagga tcaatgcctc
    68941 caagtcgctg aaatgataaa aaagagtaaa acgatggctt cttatcttga acataaacag
    69001 tcaatggaag aatctgcaaa agtttgccag ttgaaagaag cgttcttgtc taagaaagaa
    69061 gcatttgaaa atgtagcggc atatggtgag tatgcacctg attatcgtga aaaaaaacga
    69121 gctgttcgaa aagcaaaaag acagcttgat atggatgagc atgttgcagc tttccgatat
    69181 agtgaaacac agctgcaaag tctgttggat caaattgtcc aagtacttgc cgaagaagtt
    69241 tctaatgaaa tcaaagtaga tgcaggtagc ccgttttttg aaacgaaaaa acactttgga
    69301 tgcggaggta attgtcatgc aattagacaa tagtgaattt gaaataacaa aacgacgcgg
    69361 gctgatcgta tgggtctaca gcttaaaaca attaaagaat ctgaaaaagt tcggcttgtt
    69421 gcattatgtc tcaagaagaa tgaaatatgt cgtgctttac ttaaatgaag agacattgga
    69481 agaaacagaa gaacgaatcc gtaaattaca ttttgttcga aacgtagaac gttcttaccg
    69541 accggatatc gaaatgaatt ttgccgaaaa aataggaaac aaaacagtat taaaagacga
    69601 aggtttcgaa attgaagagc taaatacaga aatccgatta gctgaacatc tttaaaaatc
    69661 tcttatgagc agtttttaaa taaaaaataa cttggataac gatcgatttt tgatcattgt
    69721 ccaagtattt ttttggtata ctagtaccag taccatttct aaggagtgag tagatgcgga
    69781 taatatcagg aaattatggc gggcgccgtt taaaaagttt agcaggggcg aacaccagac
    69841 caactacaga taaagtaaaa gaatccatat tcaatatgat tggaccatat tttgatggag
    69901 agacagtatt ggatctgttt gcaggaagcg gtggtttagc tatcgaagca gtatctagag
    69961 gctgcagtca tgcggtatgc gtagacaaaa attaccaagc gctaaaaatc atcaaagaaa
    70021 acatcgaaat tacgaaagaa ccagagaaat ttaccacaat aaaacttgat gcggacaaag
    70081 caatcgaacg gctagcagcg gagaaacaac aattcgacta cttgtttctt gatccgccat
    70141 atgcaaaaca aaaaataatc gatcaaatcc ataaaatgga agaactggga cttttttcta
    70201 aaaccgcagt tatcgtatgc gaaacggata aaacagtcga attgccagaa actgtggctg
    70261 gattccatca aataagaaaa cagatttatg gcataacggc cgtaactatc tatagaaaag
    70321 agggaaatca atgaaacgtg cattattccc aggaagtttt gatcctttta caaaaggtca
    70381 cttagatacg gtggaacgtg cggctaaatt attcgatgag gtagtaattg gtgtttttat
    70441 caatacttca aagaaaagtt tgtttccccc agaagaaaga atgacattga tcacaaaagc
    70501 tgtttctcat cttcctaatg taaaagtcat gcatcaagaa aatcaattga cggtagaaac
    70561 agcaaaagag attggtgcag atgcgttgat cagaggcata cgaagtatca aagactttga
    70621 atatgaacga gagattgctc agatgaatca tcatctatat gatgaattgg aaactgtctt
    70681 cttattagca aaaccagaat atagtcacgt gagttccagt attttaaaag aagtactgca
    70741 ctttggcgga gatgtgagca gctacttacc gccagtgatc aacgaagctt tagctggaaa
    70801 gcgtgaatca aatgaaagct aaacaatggt tgaaaacagt actgattatc atatttggaa
    70861 tgttgatcat tggatttgta gtagttccct tgccgtatta tgtagaatca ccgggagcca
    70921 cgatcgatct gaaagaacta attacggtca atgataagga agataaaggt tctgggtctt
    70981 tctctcttac ctctgttggt atcaggcaag ctacaggttt cttagcttta aaagctaaaa
    71041 tgaccccttt tgaagaattg atcagtgaag aagaattgac tggtggggcg acaaatgaag
    71101 aatataatca aatgcaacag tattatatgg attcttccca aaatgcagca atcgaacaag
    71161 cgttaaaact tgcagacaag ccttataaaa tggaattcaa aggcgtatat gtcatgagtg
    71221 tagagaaaac atcgaatttc tttggcaagc tttcagttgg agatacagta acaaaagtag
    71281 acgggaaaag ctttcaaagt acagaagcat ttatggatta tgtaaaaagc caaaaagttg
    71341 gacaaacaat cgaaatcagt tatttgcata atggtgaaga aaaaacagct tctggtgatc
    71401 tgatcgagtt accaacagat aaaaaggcag gaataggtat cacgcttact gaccataccg
    71461 agatcgaatc agatacagat gttcgtatta attctggctc tatcggtggg ccatcagcgg
    71521 gattgatgtt cactttagaa atctatgaac aagtcactgg taaaaacttg cgacatggta
    71581 agcaaattgc aggaactgga acgatcaaca gtgaaggaga agttggccga atcggaggaa
    71641 tcgataaaaa agtggcaagt gcggataaag ctggcgtaga gattttcttt gcaccagatg
    71701 atacgatttc agacgatgtt aagaaagaat atcctgaaat aaaaaccaac tacgaagaag
    71761 caaaagctgc cgctaaaaaa ttgaattcct caatgaaaat cgtaccagta aaaacagtac
    71821 aagaagcgct tgactatcta gagaaaatga aatgaaacta aataattaaa gaggggttgt
    71881 g
//
LOCUS       DAPBAF010000008        68682 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.008, whole genome shotgun sequence.
ACCESSION   DAPBAF010000008 DAPBAF010000000
VERSION     DAPBAF010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 68682)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 68682)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68682
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.008"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(592..1983)
                     /locus_tag="RD451_000631"
     CDS             complement(592..1983)
                     /locus_tag="RD451_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HDT7565920.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
     gene            complement(2196..2582)
                     /locus_tag="RD451_000632"
     CDS             complement(2196..2582)
                     /locus_tag="RD451_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HDT7565921.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            complement(2638..3261)
                     /locus_tag="RD451_000633"
     CDS             complement(2638..3261)
                     /locus_tag="RD451_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HDT7565922.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            complement(3325..3993)
                     /locus_tag="RD451_000634"
     CDS             complement(3325..3993)
                     /locus_tag="RD451_000634"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HDT7565923.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            complement(4005..4445)
                     /locus_tag="RD451_000635"
     CDS             complement(4005..4445)
                     /locus_tag="RD451_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565924.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            complement(4504..5174)
                     /locus_tag="RD451_000636"
                     /pseudo
     CDS             complement(4504..5174)
                     /locus_tag="RD451_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(5359..5757)
                     /locus_tag="RD451_000637"
     CDS             complement(5359..5757)
                     /locus_tag="RD451_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HDT7565925.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            complement(5754..6527)
                     /locus_tag="RD451_000638"
     CDS             complement(5754..6527)
                     /locus_tag="RD451_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HDT7565926.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            complement(6524..7207)
                     /locus_tag="RD451_000639"
     CDS             complement(6524..7207)
                     /locus_tag="RD451_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HDT7565927.1"
                     /translation="MLKNFKEVIAAILPMTVLIVILTFVFAPLEGEDLASFLVGAAIM
                     MIGMTLFLFGADYSMMEVGDLVGKYMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQ
                     QVYDISDGEIGRVLLIGIVSVGTGVFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFT
                     SSEFMPIAFDSGGVTTGPVTVPFILALAGGMTSMIKQKKNENDSFGMVGIASLGPILA
                     VMILGVIFQ"
     gene            complement(7374..8261)
                     /locus_tag="RD451_000640"
     CDS             complement(7374..8261)
                     /locus_tag="RD451_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDT7565928.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(8258..9127)
                     /locus_tag="RD451_000641"
     CDS             complement(8258..9127)
                     /locus_tag="RD451_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDT7565929.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(9264..10550)
                     /locus_tag="RD451_000642"
     CDS             complement(9264..10550)
                     /locus_tag="RD451_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HDT7565930.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            10823..11401
                     /locus_tag="RD451_000643"
     CDS             10823..11401
                     /locus_tag="RD451_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HDT7565931.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            11401..12330
                     /locus_tag="RD451_000644"
     CDS             11401..12330
                     /locus_tag="RD451_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7565932.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            12327..14063
                     /locus_tag="RD451_000645"
     CDS             12327..14063
                     /locus_tag="RD451_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HDT7565933.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(14126..14962)
                     /gene="pheA"
                     /locus_tag="RD451_000646"
     CDS             complement(14126..14962)
                     /gene="pheA"
                     /locus_tag="RD451_000646"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HDT7565934.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(14959..15468)
                     /locus_tag="RD451_000647"
     CDS             complement(14959..15468)
                     /locus_tag="RD451_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HDT7565935.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(15461..16756)
                     /gene="aroA"
                     /locus_tag="RD451_000648"
     CDS             complement(15461..16756)
                     /gene="aroA"
                     /locus_tag="RD451_000648"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HDT7565936.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(16769..17860)
                     /locus_tag="RD451_000649"
     CDS             complement(16769..17860)
                     /locus_tag="RD451_000649"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HDT7565937.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(17877..19043)
                     /gene="aroC"
                     /locus_tag="RD451_000650"
     CDS             complement(17877..19043)
                     /gene="aroC"
                     /locus_tag="RD451_000650"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HDT7565938.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(19045..20109)
                     /gene="aroB"
                     /locus_tag="RD451_000651"
     CDS             complement(19045..20109)
                     /gene="aroB"
                     /locus_tag="RD451_000651"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HDT7565939.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(20142..21164)
                     /gene="aroF"
                     /locus_tag="RD451_000652"
     CDS             complement(20142..21164)
                     /gene="aroF"
                     /locus_tag="RD451_000652"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HDT7565940.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            complement(21823..22797)
                     /locus_tag="RD451_000653"
     CDS             complement(21823..22797)
                     /locus_tag="RD451_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HDT7565941.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            complement(22778..24661)
                     /locus_tag="RD451_000654"
     CDS             complement(22778..24661)
                     /locus_tag="RD451_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HDT7565942.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(24679..26904)
                     /locus_tag="RD451_000655"
     CDS             complement(24679..26904)
                     /locus_tag="RD451_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HDT7565943.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEEKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            27019..28053
                     /locus_tag="RD451_000656"
     CDS             27019..28053
                     /locus_tag="RD451_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDT7565944.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            complement(28120..29133)
                     /locus_tag="RD451_000657"
     CDS             complement(28120..29133)
                     /locus_tag="RD451_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDT7565945.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKQLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(29211..29399)
                     /locus_tag="RD451_000658"
     CDS             complement(29211..29399)
                     /locus_tag="RD451_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HDT7565946.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
     gene            complement(29839..29967)
                     /locus_tag="RD451_000659"
     CDS             complement(29839..29967)
                     /locus_tag="RD451_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HDT7565947.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(29970..31343)
                     /gene="rlmD"
                     /locus_tag="RD451_000660"
     CDS             complement(29970..31343)
                     /gene="rlmD"
                     /locus_tag="RD451_000660"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HDT7565948.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(31454..32509)
                     /locus_tag="RD451_000661"
     CDS             complement(31454..32509)
                     /locus_tag="RD451_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HDT7565949.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(32519..33949)
                     /gene="gatB"
                     /locus_tag="RD451_000662"
     CDS             complement(32519..33949)
                     /gene="gatB"
                     /locus_tag="RD451_000662"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HDT7565950.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(33946..35418)
                     /gene="gatA"
                     /locus_tag="RD451_000663"
     CDS             complement(33946..35418)
                     /gene="gatA"
                     /locus_tag="RD451_000663"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HDT7565951.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKTTFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(35418..35723)
                     /gene="gatC"
                     /locus_tag="RD451_000664"
     CDS             complement(35418..35723)
                     /gene="gatC"
                     /locus_tag="RD451_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HDT7565952.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(35829..37865)
                     /gene="ligA"
                     /locus_tag="RD451_000665"
     CDS             complement(35829..37865)
                     /gene="ligA"
                     /locus_tag="RD451_000665"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HDT7565953.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTIKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(37882..40116)
                     /gene="pcrA"
                     /locus_tag="RD451_000666"
     CDS             complement(37882..40116)
                     /gene="pcrA"
                     /locus_tag="RD451_000666"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HDT7565954.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLVNPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            40271..41830
                     /locus_tag="RD451_000667"
     CDS             40271..41830
                     /locus_tag="RD451_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HDT7565955.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVVGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQNVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
     gene            complement(41941..43872)
                     /locus_tag="RD451_000668"
     CDS             complement(41941..43872)
                     /locus_tag="RD451_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDT7565956.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAVAEA"
     gene            complement(43890..44804)
                     /gene="pfkB"
                     /locus_tag="RD451_000669"
     CDS             complement(43890..44804)
                     /gene="pfkB"
                     /locus_tag="RD451_000669"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HDT7565957.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(44801..45553)
                     /locus_tag="RD451_000670"
     CDS             complement(44801..45553)
                     /locus_tag="RD451_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDT7565958.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLLNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(45712..45921)
                     /locus_tag="RD451_000671"
     CDS             complement(45712..45921)
                     /locus_tag="RD451_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565959.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(45932..47260)
                     /locus_tag="RD451_000672"
     CDS             complement(45932..47260)
                     /locus_tag="RD451_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565960.1"
                     /translation="MIGEDKLLMTIQLTDLNEEEKKQEISDWAILTRLLIQPTFIRSF
                     TQQADPYDLRKLQEKIMLASVRDESWLVVGNDENECSFRLEDNQLLIKNVLSISVFKE
                     KQFLIRDFIQKKMIAHGVFAYMRAYSEFIYHNTKQISQRLLFEKKDEIEHLPKMKQQN
                     GEVVVDCNQFPGYDLFYQGLCFTSCWEMYYSRYYHQIIPKPIFLDIQQVEKVKELENE
                     VICIQLYRDPFNWQKPNNQMFQSYFRDQLGFDHLAWDNGVGLLKPPFVEYIYTDHTIQ
                     SVQYQNAQMQPVPKKNASFFVTKSYDIQQGDYKERRVRGTLNAQAYFPWVDENRSRMM
                     CYKVIDPTVALDNGIEAYCYYIREYLEVEVTDEKYQEYLLSLRIYVPSESLSELPLKE
                     IKHRLSDVTFKRIKKKRRSIQFDVKKGEQHLRVQFLDYRELEQLITLQKI"
     gene            47396..47551
                     /locus_tag="RD451_000673"
     CDS             47396..47551
                     /locus_tag="RD451_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565961.1"
                     /translation="MGLKFERTDNLDKLFESFAVDPEKTVAPKEEIDRFLKPQPQNEK
                     KKDKKQK"
     gene            complement(47625..48212)
                     /locus_tag="RD451_000674"
     CDS             complement(47625..48212)
                     /locus_tag="RD451_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HDT7565962.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(48295..49545)
                     /gene="clpX"
                     /locus_tag="RD451_000675"
     CDS             complement(48295..49545)
                     /gene="clpX"
                     /locus_tag="RD451_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HDT7565963.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVELAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(49792..51081)
                     /locus_tag="RD451_000676"
     CDS             complement(49792..51081)
                     /locus_tag="RD451_000676"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HDT7565964.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(51235..52167)
                     /locus_tag="RD451_000677"
     CDS             complement(51235..52167)
                     /locus_tag="RD451_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565965.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHQVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLKEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(52324..52983)
                     /locus_tag="RD451_000678"
     CDS             complement(52324..52983)
                     /locus_tag="RD451_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HDT7565966.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSLYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAVFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(52986..54011)
                     /gene="sppA"
                     /locus_tag="RD451_000679"
     CDS             complement(52986..54011)
                     /gene="sppA"
                     /locus_tag="RD451_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HDT7565967.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELAPNVLEEGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAIR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(54024..54314)
                     /locus_tag="RD451_000680"
     CDS             complement(54024..54314)
                     /locus_tag="RD451_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565968.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAQAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            54723..56528
                     /gene="glmS"
                     /locus_tag="RD451_000681"
     CDS             54723..56528
                     /gene="glmS"
                     /locus_tag="RD451_000681"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HDT7565969.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDASDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(56600..57955)
                     /locus_tag="RD451_000682"
     CDS             complement(56600..57955)
                     /locus_tag="RD451_000682"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HDT7565970.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(57979..59148)
                     /locus_tag="RD451_000683"
     CDS             complement(57979..59148)
                     /locus_tag="RD451_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565971.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(59145..60032)
                     /locus_tag="RD451_000684"
     CDS             complement(59145..60032)
                     /locus_tag="RD451_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HDT7565972.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(60221..63913)
                     /gene="nifJ"
                     /locus_tag="RD451_000685"
     CDS             complement(60221..63913)
                     /gene="nifJ"
                     /locus_tag="RD451_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HDT7565973.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIFPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPTMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLDNANPN
                     LAKALFEKTVHDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARRAARAERRKKMEQATKEKKEK"
     gene            64112..64633
                     /locus_tag="RD451_000686"
     CDS             64112..64633
                     /locus_tag="RD451_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HDT7565974.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLACPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
     gene            complement(65332..65889)
                     /locus_tag="RD451_000687"
     CDS             complement(65332..65889)
                     /locus_tag="RD451_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565975.1"
                     /translation="MRNLSNRNKILIIIVVIAVFHLGTNAVLSRIILGPKPPRPEITR
                     GEFDFRLEYEVDGERIVIEDTIVALFDGFSADAGSMAWYRTWRLHLASDRRSRNILLD
                     ELEDGRRIYYVPESANYSMGDVQKKREPNPNWYPFNGVTIEYPRNKTPEIGAKFISGL
                     EDLYDRFGIRLISWEHDPPIENRFE"
     gene            complement(66068..66679)
                     /locus_tag="RD451_000688"
     CDS             complement(66068..66679)
                     /locus_tag="RD451_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565976.1"
                     /translation="MNSNRGNKMEYNGSMRIVQIIFWITSGIVIIGGVFLMLPSLIFP
                     FFALISPKIPEPEITYGEFPFRIEYELDGQINIIEDTVIAEFNGCEFSAGSMKRERRW
                     RSRLASGREDLPFGDDLGIYFSRGSAQYYMGENVQSMSLKPHIALRNLEEGFKREVDF
                     ILGESGYIRTVLNFGEAQEVLTQYGITLINWEISEPIVNNFGD"
     gene            complement(66792..67049)
                     /locus_tag="RD451_000689"
     CDS             complement(66792..67049)
                     /locus_tag="RD451_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565977.1"
                     /translation="MRAVHVNPTIEITMIGHSKGGAEAANSVAINTNAIIFNPATVNL
                     SAYELDSNTYTANMVAYVVEGDALNVVFGGVYTYWRINHVR"
     gene            complement(67646..67924)
                     /locus_tag="RD451_000690"
     CDS             complement(67646..67924)
                     /locus_tag="RD451_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565978.1"
                     /translation="MEKHNITGSMYVDDQWFISTDEVKIAAIRRDYLQKIHKIKDPNG
                     KKARLIITLITSNGKKLKLAGSYDNVKKFEHWYLQKDSISLNKQFEKN"
     gene            complement(67958..68209)
                     /locus_tag="RD451_000691"
     CDS             complement(67958..68209)
                     /locus_tag="RD451_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565979.1"
                     /translation="MKEKPINKWSLYKNSMFGVVIFGVCAGLFLFILLQTVTLFSSNP
                     TYGWRDSIALGMFAGGYGFLLLFSILTLSPIHGLIQLWK"
BASE COUNT        19204 a        14835 c        12081 g        22562 t
ORIGIN      
        1 ctgttctaac attctcaact ttgtcagttt accataggaa aatgggaaaa tctacgaaag
       61 ctctcaacag aatcgtccta cttaaatacg cttttcttta ataataaata agttggttgt
      121 ttttgttatt tgcgctttca cttttcggaa taaataatgt gtatttatat ggaataaata
      181 aaaaaagagg tcgtgactaa aaacaagtca caacctctgg taaacggtgt tctcctgaca
      241 actcctcggt cacaagacac aatattcaac aaacatgaga agctattttt tgaaattgct
      301 ctttgtgact cagagtgaaa cggcaggctc acgacctctt tcttaaacgg tgttcaaaag
      361 cttgcatctg cggtaataag ctcaaccaaa cgtaaaatat gaggaactat ttttgtttgg
      421 ctgttcttat tacttgatgc agggcagctt tttcacaacc tcttattcac ggtgtttcag
      481 aagtagcttc tcggaaataa gccgaaattt cacaaaaatt tgagaaacta tttttaggaa
      541 acttcttctt atttcttaaa gctgaccact tctatcacaa cctctttttg actatgcatt
      601 cacatcgatc actttagaat catcattgat gacatcgcga tctaaatctt tgatgcgtgc
      661 acttgtcacg ataccagcta ccatgctacc gctgacgttt actgctgtac gtgccatatc
      721 gattaatggt tcaacagaga taactaaccc aacgattgct actggcaagt tcattgcccc
      781 taaaacgatc agtgaagcaa atgttgcgcc cccaccgact ccagctacac caaaagaact
      841 gattgttaca attgccacaa gcatcaaaat aaattccaaa ctaaagacat tcactccagc
      901 tgctggtgcg acgatcgttg ccaacatagc tggataaacg ccagcacagc cgttttgtcc
      961 aatagacaaa ccaaaacttg ctgagaaatt agctgttgca tcatctactc ctaaagcttt
     1021 tgtctgagtc tcgatattca atggcaaagc tccagcactt gaacgtgaag taaacgcaaa
     1081 gctcaatacc ggaaaggctt ttttgaaata gttgattgga ttgacttttg caccaatcaa
     1141 aatcagtgag tggacaatca aaacagcaag caatgctacg taagaagcaa cgacaaattt
     1201 acctaaattg acgatagctg caaaatcact tgttgccaaa acgtttgtca tcaaagcaaa
     1261 tactccataa ggtgtcaaac gcaaaacaag cgtcacgatc cgcataatga ttttatacag
     1321 actgtcgact aaatctgaaa agaatgctgc ttcttttggc gcttttcttt tcacgcctag
     1381 ataagcgatt ccgacaaatg ccgcgaaaat aacgactcca atcgtacttg ttgcacgact
     1441 acctgctaaa tcagcaaaaa cgtttttagg gataaaggat aaaatctgct gtggaatcga
     1501 taagttttca actgtttcct gacgtgttgc cagttcagag attcgtgctg tttctgcagc
     1561 tccttgtgtg aatttagctc cttggagtcc gaacagcatt gttgaaccaa ttccgatcaa
     1621 tgctgcaata gctgttgttc caagtaaaga agtcaataca gtcgcactaa ttttccctag
     1681 cttttcagaa actttcattt ttgtgaatgc accaatgatc gaaataaaca ctaaaggcat
     1741 aactagcatt tgcaagaatg atacatatcc ttgacctaca atcccgatcc attccattga
     1801 ttgagtaacg actttgtcgt ctacaccaaa gatcaattga agcagaccgc caaagacgat
     1861 accaactcct aatgctgtaa agacgcgtgt tgaaaatttt gtatggcgct tttgcatacg
     1921 atagaacaca tataataatg ccgcaaaaac tagaaccact aaaactgtga tgagtgttgt
     1981 catttttctc ctcctcatat tattaatgac aagtccatcg aaggaagtaa aggttcccga
     2041 gaatgattct tcaaccatcc tcctgaaaaa atttttttca gtgactttta tattttagac
     2101 gatttttatc gaaatgacat tctttttgct tacaattagt aataaaaaaa catacctgtg
     2161 atagctttaa tctatcgcag gtatgttttt actgtctatt cttgtttttc tgattgaaaa
     2221 ttcaatttta ccccaggctg atctaaggcg atctctgtca cctcataaga cattcggcgt
     2281 acgatatcga ataacggtgc tactagctcg tccacttctt cttgtgtgac atcattttga
     2341 ccttcaattt tccgattgag gatatgattg atctgactca cacttccaga taaaacatat
     2401 gtatcaaaca ctaaacggaa ctctaagcgt gctcctacga tgctatgttc tttcggatag
     2461 ttttcgatcg tttcttttaa aggcgagaag cctactttca aatctgtttc tacttcttgg
     2521 ttcggcaatc tcatatcata atgaaatgct tctacaactt ctttttgtct tctgatttcc
     2581 atataatttt atcactcctt tatgaaaatt ataacatatc tcctttgaaa ggggatacta
     2641 ctttttaatg atgctctgca aggtaaggat ttcattcaga tttcctacca cataatctgc
     2701 cgggatctca cccagaaaat gatcgatgtc gtaaagacaa gtagcgactc ctgcattttt
     2761 ccctgcttcg atatctaaac gacgatcgcc gatcatcatc gtgtctgttc tttctaaatg
     2821 aaaagtatcg atcaaataat ttaaagatgc tggatcaggt ttacgaggaa agtcctgatc
     2881 gatccctact acttcctcaa tcagatgtgc caatcgatgt tcttttaaca ggccccatgt
     2941 tgattctgtc aaacggtggg tcaggatgaa atgacgaccg ccgttgtctt ttagcatttc
     3001 cagtacttgt ttcgtttctg gaaatggacg ggaaacttcc gtactttctt tttcatatcg
     3061 gtgaaataat tcattaaact ctctggcatt caagtttgat tcattgatca aataactagt
     3121 agaatacttt ttcattttga agtagatttc ttttttgtcc atactgatac caaaatcttt
     3181 tagtgcttgc catgcaccat ctaccattgc gggatacgta tcaaacaatg taccatcaaa
     3241 gtcccatata taatttttca tgttcctttt gttccattcc tttgcttctt ttttctatct
     3301 ctcactttta gataaaggtg ttctttaaag tatttttttg tccagaattg tcaaatcatc
     3361 tgctaatgta tactggattg gttgtgcatt tgggatatcg atcgtatcca tttgatcttc
     3421 aggaacatct tctaaatatt ttgtcagtgc tcggatgcta ttaccatgac ccacaactag
     3481 taaatcttgc cgatctttta gttttggtgc tagatgatct tgccataagg gaatgatccg
     3541 attcactgtc atttccagac tttctccgta tgggatcaaa tgcggatcca agtgatcata
     3601 tctgcggtca aatctatttt ctgcggttaa cggcggaact tccgtatatc ctctgcgcca
     3661 tgtttttact tgatcttttc cgtatatttc tttcatctta tctttgtttt tacccacaag
     3721 atccccataa tgccgttcat ttagacgcca tgtttttatt ataggaagcc ataactgacc
     3781 catttcttct agtgcgactt gtccggtaag aatcgcacgt ttcaaaacag aggtataaac
     3841 ggcatcgaat tgaagtccgg cttcaagcat tttttgaccg gcaactgctg cttgttcttt
     3901 tcctttttct gttaaggcga catctagcca tcctgtccag taattttcaa aatttgcttc
     3961 gctttcgcca tgacgtaata atactaattt cattcttttc tcccttaaac attcgtttcg
     4021 aattttatac cacatgtttt gcatgtcaca cgtattcgtc cttttccttt aggtgcacgc
     4081 tgcttttgat gacaattcgg gcactcaaaa aaagtataac tttttcgatc cattttgact
     4141 tgctttttgt tttttatctg atgatatttt tctttgactc tatcaagata tttcaaataa
     4201 cgttgattct catttagtct ggggtagatt ttttttgata ggaaacgaaa tatcatccat
     4261 ccgaaaaaga cgatgaacaa caattgtccg attctatagg gcaaccaacg acttagcaaa
     4321 ctaaagacaa gcgcagcgat caatagaccg cgattcaact gatcaaattt cgcatatctt
     4381 ccctgcataa gtttgtgata gttctgctga aatcgtatta gcctttctaa ccatgtttgc
     4441 atcatattat ctcctccatc atctaatatt tattatgaca aaaaaatcca aaaagaaaaa
     4501 gccttaattg gccttttcca ttgcaacttg gtgaaggaca ttccgatttc tggtaaagtc
     4561 aatcacaatc actttctttt tatcttctct gttgactact cgaaatgtgt ccgtcaatgg
     4621 aagaaacagc ttcttagatg gtagctgttg catacgtata aaacgatgga tcatcgtaat
     4681 caattgagga aattgaatag acgtgtgaag cagacctgga tattttttca acagctgtgt
     4741 cgttttgatc agattccgtt ttttactgat cacttttaaa aagcttttta gaatcttttg
     4801 ctgacgtcta aaaatagaaa aagaattttc gtcatctatt gataacgcat ttgtttttgc
     4861 agttctgctg cagtcagatg gatcttccca tcgtttgtat cgatcattaa accttctgga
     4921 aacagttcaa ccactgctcg atcccaagat tcaagagaaa gctcgatata atcttttact
     4981 ggtaattcca attctacctt aaaaaagtgc aaaacagccg acagcccttc tgcttgatag
     5041 atttctccta atgttagccc ctctagatgg aactctggtg aaaaatgcag caatgtttta
     5101 ttttcctgca attgaacata tagaaatgta gatcgctcaa tcagagtatc ttttaaaaca
     5161 actaaaaaat tcatttttct cccccttttt tcatcatttt taaaatagca tattttgaaa
     5221 agaaagtctg atgcttagag tagaatttca taaaaattta ctatttcata agtattcacg
     5281 agaaaaatac aaacaaaaaa gcggaaataa cgctcatccg ccttcttgtt tgtgtttatt
     5341 tcctcttcaa acgcttgtct atgattcaga cttttctcta tcgttatttt catctaaaag
     5401 ttcttgcatt ccgataattt ctcgatattg atgaatctta gtgataccaa tgactttgtc
     5461 tacatcaata ctaaaacaaa taccattacc tggaatatcg atgttgatgc cttgaccaat
     5521 cgcatccatt actttattcg tcaaactatc gggtactaat gtcaacacaa tatctttttc
     5581 tggcgaaatg tccaaaccta aaaatttccc tgaatcatgt acaccagaac ctcttccatg
     5641 taagatcgtt ccgcctgctg cacctgcttc ttttgaaaag tcgataacat cttcgcccat
     5701 tcctccgtca acgatcgtca caatcatgtg aagattcaat gctacaagat ctttcatttg
     5761 ctttccccca atttttgcaa tctttctttt tcgattctgt ctttttcatc ttttcgttta
     5821 taaatatatc ctagtactaa agtggataat attggtgtca atgcaatcat tgcaaccaca
     5881 ccaaacccgt caatgatcgg atctcttcct tcaatttgtg cagcgattgc cacgctcatt
     5941 gataaaataa atgtcgaaca catcgggccc gttgctactc caccgttatc aaaagccatt
     6001 gctaaaaaga tcttgtccac ttttcgtcct aaaataaatg ctagcccgta tcctgggatc
     6061 aagaaataat aaagagagaa tccgacgagc aaacgccaca tagacaatcc tactgctgcg
     6121 ccgatcccaa ttgaaattac catcagcatg attttcgatc ggattctccc ctcgctcaat
     6181 tcttcaacct gtttgatcat tacatgaatc gccggctcag caaaccctac taagaacccc
     6241 attaaaaagc caaggggaac cagtatataa ttgtaaggca atcccgcaat agcactgcct
     6301 aaatgctgtc ctaccggtac ataagccata ttgactccgt gcaggaaaag gatcaaccca
     6361 atagtcgtta tcaagaaacc tttcataatg tcaaagaaac gctttttgcg catacgaaaa
     6421 ctaatgatat tcattaaaac aaataggatt acgataggtg ccactgccaa aatgacttcc
     6481 atggtaacga tttcgattcc atctatcact tgctgccaga aactcattgg aagatcaccc
     6541 ccaaaatcat cacggcaaga atcggcccta acgaagcaat accgaccatt ccaaaactgt
     6601 cattttcatt tttcttttgt ttgatcatac tagtcatccc tccggcaagg gccaagataa
     6661 atggaacagt tactggacca gtagtcactc cccccgaatc aaaagcaatc ggcataaatt
     6721 cggaactggt gaaaaatgag gcgatcaaaa cgcctatgta gcctatagcc atcaattgat
     6781 aataggatag cttgaatacg acccgaagca gcgcaaaggc tagaaatact ccagtgccga
     6841 cgctgacgat cccaatcagc aacactctgc caatctctcc gtcagatata tcatatactt
     6901 gttgtcccaa aacttgcacg gaaggttcag caatcgtgat cacgatcccg atagcaaatc
     6961 ccaaactgac caaaacggtc aaacttttct ttttgatcat atatttccct actagatctc
     7021 cgacttccat catagaataa tctgctccaa acaaaaagag cgtcattccg atcatcatga
     7081 ttgccgcacc aaccagaaat gaagcgaggt cttctccttc taacggtgca aaaacaaacg
     7141 ttaaaatgac aatcaggaca gtcatcggca atatagcagc aatcacttct ttaaaatttt
     7201 ttagcatgta tcctcctcct ttactcttta agtttacctt aaaatgaaag agttttcgag
     7261 cacaaactta aaacgttatc atttaatttt tctcaacata aaataacaca cgtcccaaaa
     7321 gtatcttttt acttggaaaa atgactttga aggaacgcgc ttattgtgtt tttttatttt
     7381 acagagccga tcattccttg aacgaattgc ttttgcaaaa caaaaaatac gatggcagtt
     7441 ggtaaagtag cgatgactaa tccagccatg atcattccat agtctggtgt ataggaagca
     7501 cccatagcag ataaaacaag cggaaccgtc cgtttatcag gagattgcaa agctactaag
     7561 ggccataaat aattgttcca gctactcatg aatgtgatga ttgcagccgc ggcataggta
     7621 tttttagccg tcggcatata cactctaaaa aaaatactta gttcttttag accgtctaat
     7681 cgagcggctt ctactagatc ttttggaaaa gatttaacat tttgtcgaaa gaagaagatc
     7741 aaaaaagcag tgctaacaga tggcaggatg acaaccaaga aactgttgat tcccaaaacc
     7801 gttccgttca attgtgaaaa cattcgatat aaagggatca tcaatgccgc aaaaggaacc
     7861 atcatcgata gcagtagaat attgaaaatt aggtcttttc gtttactttg ataaatctca
     7921 aatccatatc ctgccattga cgaaatcagc aatgcaaaca cagtggtcac caaagcgatc
     7981 atcgctgaat tccaaaggga acgagtaaaa ttcagctcat tggaaaacaa attttgaaaa
     8041 ttgatgatca agttactgcc aatctttatt tttcccgatg tgatatccac gggtgtattc
     8101 gtcattccca aaaccatcca gacaaaaggg aaaatggaaa taaatgatag gatgcttaat
     8161 gctgtatact ttaatactga cccaattgtc gaacgaagtt ctaatgcttg ttttttgacg
     8221 ttggggcgtt cgattgtttc tttttctacc atatttttca tcgactttct cctcctactt
     8281 tcgtttggat tatcgacaat atcacaataa aggaaacaat aacaaaggaa actgctgccg
     8341 catatccaaa attaggcgtg aatttataac tcaaattata gatgtattga gatagggtgg
     8401 tcgttgcatt tgctggtccc ccgccagtaa tattttgtac ttcatcaaaa agctgcaatg
     8461 tcccgatcgt cgaagtaatg gaagtaaaca aaatgattgg ttttaaattt gggatcgtca
     8521 ctttgataaa ctgctgccat ttagaagcac cgtcaataga tgctgcttca taaatctccg
     8581 aatcaatatt ttgcatgcct gaaaggaaaa aaatcatatt gtatccagtc caacgccaag
     8641 tgatcgaaag aatgatcaga actctcgccc aaattggatg agtcaaccag ccaatcggtg
     8701 tgtcaatcat accaatgccc aacaacaagt tgtttacaag gccagattga gaaaatagac
     8761 ttttcatgat cagagaataa ctgaccatcg aagtgataca tggaagaaag atagcggttc
     8821 gaaacaaccc tttatatttc aactttttat catttaaaag gttggaaata aaaagtgcta
     8881 gaaacaacat gatcggtact tgtacaagta aatacaggaa tgtattaaaa aaagcttttt
     8941 taaaagttgc atctgtcaac atccgctgat aattacctaa cccgttaaat gtcatattga
     9001 cagggggacc actttgaaaa gacgtgatca aagccaaaac catcggaata aaaaccatga
     9061 ttgatatcaa aatgactggc aagattaaaa aagcatgccc gtttttgaat aaatctttct
     9121 gcttcattct tttccctcca attctatcat tgattatcta catgaaaaga caagaaagac
     9181 aatatctgta aggcagacgt gatctttttt gtcttttcgt ttgtctgatg aaaaagcgaa
     9241 gaaattcact tttttaccac cgatcaatta gccaattgtg cttctacttg tttttgtgta
     9301 tctgctagta ccttgtctgt ctcttctcca ttgatgattc gatgaagagc ttcagctacg
     9361 actgcttcaa ttgcataggt ctcatgtccg taattcactt ctggtatttc agatgtccat
     9421 gttgaaaaat cgtcaaagat cttttgacca ctgtaaaatt cagaagcttc ttgataagct
     9481 tcttgttcat tcgcgctaag catcgtagat actagtccga tttctttcgc aagagtgccc
     9541 atcagttctt cattcgaagc aaacgttgct tctaggaaat ctttcgctga atcttctcca
     9601 gctactcctt tgatcacata ccagccagcg ccgccaaggt tagaagcttg cgctttttgc
     9661 agattttctg gaagtgcagg tattggtgca atcttccatt ttccagattg gttttctgct
     9721 ccttggatcg ttgaagaata ccaagcgcca gttgggctag aagctactgc tcctgattgt
     9781 atcgcagtta ctccagcatt ccagtcagag gtttgttcga ctagatcttc tttcaaaaga
     9841 gtggcaaaca attcaagacc atactttaaa gatgcattgt cttggatcgt gactgtctcc
     9901 ccatcttcag atgtatacca ttctcctgcc tgttgcataa tcatccttac tcgaccaagg
     9961 tcagaaggat tgacttcagc gattttcttt cccgtctttt ctttgacatc tcgcgctact
    10021 tgaatatact cgtcccactt cagattctcc atatcctctt ctgtataacc tgcttctgcc
    10081 atcagatccg tacgatagaa gtttgctgtt acgcccgaat cgaaaggaac accgtatatt
    10141 ttatctccta ctttgtttac cgcaaattta tacggtgcaa aatgatcttc ctttacaata
    10201 gcagacaaat tagcgaatgc atctggataa gaagtcaaat agccttgtat cctataatct
    10261 tcaatcaaga cgatattggg caatccttct gtattcccgc tcgctaaagc ggtgttcagt
    10321 ttctgaacga tatcatcctg agacatcgta acaacttcta tctctgtttc ttcgttctca
    10381 taaacttttt ttgcttcatt cactgctttg atattgaatg tctcatccca cgcccagaca
    10441 gtgacttttt cttctttgtc tgctgtacta ctagcacttc cgcatcctgt taagaaacct
    10501 gatgctgccg ctaaacaaac gactccagca attaactttc tgatgttcat ttttatccgc
    10561 tccttttcca tccattagtt gtttacgttt gctacattca tcataccaaa atttgaaaac
    10621 ggtttcttta ttattcagat acttcaaaaa tttctcctaa aataataaaa aaatacaaat
    10681 caactatgac aaaaggaata atcttagcat ctagaccaaa gatcgaaatg gtgaggtttc
    10741 tttaaaataa aaatatcctt gcattttctc ctagaaataa gtatttttaa attacaagac
    10801 tattcttaag gcgggtaaaa aaatgccaat acgcgtaatt cttatcgatg atgaacagac
    10861 gattttagat ggaatgaaac agttgatcaa ttggtctgag cacgggtttc aattaatagg
    10921 gactttttcc agtccgctga aagcgcttga tttttctttg gtacatgcaa tcgatatcgt
    10981 ggtcacagat gtaatgatgc ctgaattaaa tggaatcgaa ttatcgcggc tattaaaaca
    11041 gcaacaacct gaaacacaga tccttatcct ctctagctat gatgaatttg atatggttaa
    11101 agattctttt aaagaaggcg tcgctgatta tcttttaaag cctcgattga gtcctgattt
    11161 ttttctaaat tccttaactg ccgtttcaca aaaaatcaaa aaaaagccca acaaaagccc
    11221 aatcaccaat cgttatgagc agatctgcga gaatctttca cagcagattg ctggacaaac
    11281 tcgtccattg cttgaccctc ttctttttga acacaccttg tttttctgtt atataccgaa
    11341 aaacggccat tcagttcaaa acaaggctct aaacaaaaac agtcgatcac ccattcattg
    11401 atggatagcg acgattcgtt tactatttat cctgtttcta ccttttcgga agaatccggc
    11461 tatgtaatca atactgattc caaagataca cttaggaagt ttgttcaaaa gtttcgtcaa
    11521 gaagtttttc caggtgattt ttttgttgtt tctgattctt ttgcaatcca agatatcaat
    11581 gaaatattcc aagagatcag aaattgcacc aaaggacaac gtttctatca taagggaaag
    11641 aaccttgctt atcagcatga acttcttccg ttattaacca accacgagca gcaagcaagt
    11701 agttatttaa caaaaatcgt tcataaagac tacgctttag ctgtcaaaga acttgagaat
    11761 ttcttcacga cgatattgga acagcctatt gatccagctt atttgaaaca tgaggcaatc
    11821 aatcgtttct atgcattact caacgctttg gctgacgagc atgttgggaa tgaagaactt
    11881 tctttgctca agatcgccct tccttcttta ttagccgatg ctgagtattt cgaagatttt
    11941 tctattcttg tcaaagaaac acttgagaaa ctcacccact tttctgcaaa tgcaaaaaaa
    12001 gacaatttcg atatcttgac tttgatctac gagttcgtcc aggaaaatta tgagaaagaa
    12061 atcaatttac aacttttatc cgaaaaatat catttttcat atagctatct ctcagccatc
    12121 tttactgaaa aatttggtat caacttttca aaatatctaa aaaaagtccg tatcagtaaa
    12181 gccaagctct ttttgacgga aacacggctt actttgacgg aaatctgtga gaaagtcggc
    12241 tataccgaac tgggttattt ctccagagtt tttaaagaag agacaggaat gacaccttct
    12301 caataccgta aaggaacttt tgtaaaatga gaaaaaaaat caaagagcat gaactctttg
    12361 ccaaacttct gttcattttg ttcatcggtc tttttctgca agccatcgtc atttctttgt
    12421 ttatttatca tcgatcaagg gatgcctata tccagctgtt caatcaatcg aatgatgtgg
    12481 tactaaaaaa gattcaatct gaatttgaaa gtttgaatga tacaatcgag aatacattag
    12541 ccgcttttga ttctaatcca gctgtcaaaa gctatttttc caatgatcca gcccaacata
    12601 tggaacagct tcagcaacta agaacaatcc aaaaaatgaa tgactctctt tcaaaaatcc
    12661 atccaatgat cgattacgat gtattgatct ttggagaaaa tggaagaact tttgtcggaa
    12721 acgacatgct cactgccgta tctgccgatt ctttttttca atctgcgatt gctcagagag
    12781 tgaatgaacg tgctgctgat acacaaatgc tttttgcaca ccacggattg actcttcgcg
    12841 ataagaaagc acccagcgtc ttctttgtca aaaaactgaa aaatacattg aatcacgttt
    12901 acggatatgc tgttttatcg atctcatcca agcaactagc gaatcttttt caatctgtag
    12961 taaatcctga gatatcgaag atctccttca tgaacgaaga acagacgatc atcgcatcaa
    13021 atgaagaaaa tacaattggg agccgatcaa tgattttcaa aaaactaaca gtaggtgaaa
    13081 caacgatttc aaatggacag cagttgaccc gtcttcctct gtaccgccag gattgtacat
    13141 tactcagtca agtcgatctt cattctttat ctaaccaaat gggcgtgatt tttccgatta
    13201 ttttgtataa tatcgtgaca cttgcttttg ctggctcatt ggtatttatg tatttggatc
    13261 gacacacaaa atcgatctac cgcttgattg attcgctaaa acggctagag gaagatggct
    13321 taaaagctac tgttcctgta caaggaagcc atgaagtcca attgctaggg aatacgatca
    13381 atcaattgct aagtaatgct cagcatcatt atgaacagac gatccaagac gaaaagaaga
    13441 aacgttcgct tgaaatccaa actatgcaag cacagataca gccccatttt atttataata
    13501 cgctgactag cttgaaattt ttgatttggc agaaaaaaac agatgaagca gttcaaggaa
    13561 tcgacagttt cattacttta ctaagaagta cgattgggaa aaaagaagaa gtgattccag
    13621 tcaaggaaga aatcaaaagc gtacaaagtt acatcgatct tttgagtatg cgatatggcg
    13681 aaagaatctc ggctaaaata atgattcctg atgaactgca gtcattatct atgccgaata
    13741 tgatccttca accaattatc gaaaacgcct atcttcatgc ttttcacaat aaaacgcaag
    13801 gattcatcac ggtgtacggc aaaacaaaaa atcagcttct tttattcgaa gtgattgata
    13861 acggcgatgg cttcgatact gaaaatacca aacaaaaaaa tgatcatttt tcaggaatcg
    13921 gcatcagcca tgtagatgag cggatacgcc taatgtatgg cgatgcatat ggcttaacga
    13981 tccaatcagt gattgggaca ggaacgactg taacgatttg tctaccgctt cttcctaaaa
    14041 atcaatcaga atatcaaaaa taaagaatag ccaagcgctg atttttttat tttaagttaa
    14101 ataaatcaat cagtattctt gactttcatc tacgcgtctc ttctactgtc agcactggat
    14161 aacagcccaa tatttgactt tctcctccga gcatcttgat ttcttggagc gcattctcta
    14221 ctaatgtcat tggacggtcc aacaacaaat cgatcacgaa aaaatattct cccaagctag
    14281 ttttcaatgg tcgggattca atcttactta agttgatttc ccgccagcca aaagctgcca
    14341 gcattttatg aagcatccct ggccgattag caggtagtgt caagatgaca ctcattttta
    14401 ctggagctga ctgctggctg gtcatctttc ggtcaccgac gatccaaaaa cgtgtctggt
    14461 tcaactcatt atcttggata ttctcagcta agatctccaa tccaacatgc tgtgctgttt
    14521 ctaatgaagc aatcgctgct gcgtcttctt tcggatgttc tgctacatac attgctgcag
    14581 cagttgttga ttctgttgct actaaaggaa cattaggata atgcgtttct aaaaactgtt
    14641 gtgattgtgc tagtgcttgt ggatgtgaaa ggatttttgt aatctttgtt gctggattgc
    14701 ctaaaagctg ctgcttgata ggaagaacga tttcactttt aacttcgact tctggatgtt
    14761 tggaaagaag atcgattgtg tgatgaacag ctccttccaa tgaattctct acaggaacga
    14821 cagccagatc gacttgtttg cgaaacaaag cgcgcaaaca aacagggatg gaagcatacg
    14881 cagtcaattg ttctgtagga aatagctgac aagccgcctg ataagtgaat gaactttctg
    14941 gccctagata gctgacgttc atatgctttt gatcctttct ataatggtat cgatgatctt
    15001 ttctggtgtt tgattggtcg tgttgattcg atgtgtcgca ctttcttcat accaagaaag
    15061 tcgttgtgcc aataatgctt ttatttcttc tcttgttttt ccaagagcta aaggtcgaat
    15121 agacgtttca tcttgttgga tacgatcaac tagacagtcc gcttctgcct ctaagtaaag
    15181 aacaatcggc tgtgttttta aaaaacgccg attttctgca ctttggacaa tccctccacc
    15241 agtcgcgata attttgtctt catttgacag ctttcttaaa atatctgact ccacttttcg
    15301 aaagcttttt tcaccgtaat agtgaaaata ttcggcaatc gacaattgga tatgttcctc
    15361 aatctttgta tctaaatcta catactcttt ttgtaaacat tgagctaacc ctttaccgat
    15421 tgttgttttt ccagcgccca tgaaaccaat cagcaaaatg ctagccatga gcttctcctc
    15481 ctgacacaag ttctgctaaa tcgtcaaaaa atgccggata agagattgaa acagcttcag
    15541 ctccttctag ttcgcaaggt ccatcagcta tcaaagcagc tacttgcagc atcataccga
    15601 ttcgatgatc gcctctgctg gacacttttg cgccatgcag aggtgtcggc ccatggatga
    15661 tcagaccgtc tgctgtcgct tttatctttg ctcccatttt ctgtaattct tctgccaccg
    15721 catcaattct gttggtttct tttactttta attcttctgc gtctttgatg atcgtgattc
    15781 cttctgcttg agtagccact aaagctagaa tgggcaattc atcaatcaga cgcggaatga
    15841 tttctccacc aatcgttgct ttcttcaaat gactcgtctt gacacttaaa tcagccgatt
    15901 ggttctgttc attgtgattc gtctgggtaa tcgctgcgcc catctcctcc aacacatcta
    15961 agataccagt tcttgttgga ttgaccccga cattttttaa caacagttgg ctttccggaa
    16021 caagaagtcc tgctgctaga aagaaagcag ctgatgaaat atcacctgga acagttatct
    16081 gttgaccagt taatttttgc ggtccggtca ctatgatcgt tttatcttcc actgtgatcc
    16141 ttccgccaaa ttgacgaatc atttcttccg tatggttacg ggaacgttct ttttcaacga
    16201 ttacggatgt gccttctgct tgtaatgccg caaacagcaa agcagatttg acttgcgcac
    16261 tggctacagg catattgtat cggataggtg ataaagagcg ggttcctgtc acagtgattg
    16321 gtagatactg gtcattttct tctccttgca agtcagcgcc catctcgcgt aaaggttcca
    16381 tcactcgccc cattggacgt ttagacaacg aagcatcccc gaacagagta gtcgtaaaag
    16441 gctgtccagc caaaataccc atcaataaac gtatggtcgt accggagttt cccatgtcaa
    16501 ttgattcggt tggttggaca aatgagtggc taccgcgacc atgaatcttg atcacctctt
    16561 cctcttcttc gatctcgaca cctaattgtt ggaaggcatg taaagtactc agacaatctt
    16621 ctgcgcgcaa aaaattttgt atagtcgtcg ttccttcagc aattgctcca aacatgatgc
    16681 tgcgatggga aattgattta tctgctggta tcctaacagt ccctcttaat ccatgtattt
    16741 gttgtaataa ttgcatttat ccagcctcct atttgatcca gcaatgataa ctggtattag
    16801 acataatgat tctttttgct tgtaacaaat cctgttggtt tttaaaactg atttgcagta
    16861 ttcctaaaat atcttccctg gtctcttgga tcttcaaatt aatcaaagaa actcccgctt
    16921 ttccgatcag tccagttact tctgcaataa cgccaggttc atctggcaca tcgataaata
    16981 aatcaaaaaa ggcaggaatc gcgccttgct tatggacagg caactggtct cgactttctt
    17041 ttgcccgatt gaaaaaagaa aagatttccg attggttctc agtcatgatc cattctgcta
    17101 tttgtgtcat ttcttgttgc caatctgcca atcgttccaa taatatctgc ttattgctca
    17161 acaaaatatc tgtccacatg acaggatctg aggaagcgat cctagtgata tctcgaaagc
    17221 ctcctgctgc cagttgtttg gctcgcggat actcttgatt gaattgttct gcctgattga
    17281 ctaagccagc tgccagaata tgtggaaaat gacttagcat tcctgttata cggtcatgtt
    17341 ctcttgctgt aagagttaca tattttgctt tggttccgca aaatagttct tgcagttttt
    17401 caacatcttt tttcgtcttt tccaaaggtg taaagatgta ataggcattt tcaaatagtt
    17461 tagcatctgc tgcctgtata cctgatttat gagaaccagc cattggatgt ccaccgacaa
    17521 accgaagatt tttctgctca gcggatgtca cgacttgctg cttcgtactg ctgacatccg
    17581 taatgatgac gtgatcagac aagttgattc tttcaaggac atcaagataa gctaaggttg
    17641 tacggacggg aacggctaat aagataacgt ctgcttgttc tgcacctgtt tcaaaatcac
    17701 ttgcaacgta atcaacgatc tgctgttcta ctgcttgctc acgggttttt gactgactat
    17761 cccaaccaac tactatcagt tctggattgg tctgacgaat acaaagtgcc atagaagcac
    17821 caatcagtcc aagccccacg ataaaaacat gttgtgccat cttatttgcc ccctttttag
    17881 taatgtttca agtagtcacg gtactccttc actgcagctt tcaactcaac aagcgaatca
    17941 cttgggaatt ttgacaatag ctctgtcgct accacagtgg ctacaacatt ttccgcaacg
    18001 acgctagctg caggaactgc tgtactatcc gaacgttcta cacttgcttt gtaaggttct
    18061 tttgtatcga tatcaacact ttgaagtggc ttgtacaatg taggaatggg tttcatgacc
    18121 ccgcgaatga caagtggttc gccattggtc attccgcctt cgaagccgcc tagattattg
    18181 gtacgtcgga aatagcctct ttcttcttcc cataggatct catccatcac ttctgagcct
    18241 ggtaatgaac cagaagtgaa tccgacccca aattctacgc ctttaaaggc attgatacta
    18301 accacagctt gtgcgatttt ggcatctagc ttcgtgtccc attgtacgta gcttcctaat
    18361 ccagctggaa cgcctccaac gagcacttct acaattcctc cgatcgtatc tccatttttc
    18421 tttgtctgat cgatcaaatc ttttattctt tgctcaactg ctggatcaac aactcgtact
    18481 tctgacgctt cagaaatttc tttgatttct tgaatcgaga tatttccagg tatttctgct
    18541 tggattccac caagacaaat cacgtgtcct gctacgatga tgtcaagttc ttccagaatt
    18601 ttcttggcaa ttgcgccgat tgctacacgc atggtcgtct ctcttgcaga ggaccgttca
    18661 agcacattcc gaagatctcg atgatggtat ttcataccgc ctaccaaatc cgcgtgtcct
    18721 ggacgcggac gtgcaactcg ccgcagtgat tggtcttttt caggcacttc tgctacagac
    18781 atgacagttg tccaattttt ccaatcttta ttttctacca ctaaagtgac aggtgaacca
    18841 attgttttgc cgtgacggat gccagacgtg atccgaacac gatctttttc gatcttcatc
    18901 cttcctcctc tgccgtaacc agcttgtctg cgagcgagtt cgtgattgat ttcttcttct
    18961 gacagaggta atcctgctgg tagtccttca ataatggctg ttaattctgg tccatgggat
    19021 tctcccgcag tcatataacg catcttacag tcctcctaag taatctttga atgtctctgt
    19081 gggaacagga acgatttttg cttgcccaat cttttctagc aagatgatat tcaattggct
    19141 tcctcttgct ttcttatcat gggttatcgc gtggaataat tcatctggat gacttagatc
    19201 gtacgtaatc ggcagatgga atttttgaag tatcctttct aaagcagctg tcgatccagt
    19261 tggagacaag ccgatttttt ctgcatgaga agtgatggct accattccaa tagctactcc
    19321 ttctccatga ctgactaccc catatcctgc tgtattttca attgcatggc caattgtatg
    19381 accaaaattt aaaataagtc gatttccttg gtcaaagaca tcttcttcca ctacttttcg
    19441 tttgatttcc aacgtagcag taatgattgg aacagcatgt tccagaagat ctttttcgtc
    19501 tttcagctcg ttcagctgtt tccaaagcgt tgcatctgct atagctgctg atttgatgat
    19561 ttcagcgatt ccttctcgta aacgacgtac cggcaaagtt tttagaacct caggatcaat
    19621 caatacacca gctggctggc taaatgttcc gacaaggttt ttcgctttgt ttgtattgac
    19681 tgctgtcttc ccgccaatac tagaatctac ttgtgcaagt agcgtagtcg gaatttgaac
    19741 gaaatggatc ccacgcatga acgtcgaggc cacgaatgct gctagatcac ccaccattcc
    19801 tccaccaagt gcaagtatcc catcgctgcg ggtaaaatca ttatctgcta aaaaatcgta
    19861 taactcagct gcttgttcta aagatttact ggtctcaccc gccggtacga ttgaaaggac
    19921 tggttcaaaa ttagcttgtc tcaattggaa catgattttt tctgcatata gtggagcaac
    19981 gtttgtatca gtgatcacag ctactttttg aggtctccaa atcgtttgaa gccatgatcc
    20041 agcctgttct agtgcgcctt tttcaatatg aatatcgtat ttttggttat caacatgtac
    20101 agtaagcatt cgtttcactt ctttctttta aaaagctgga attaatcgag tgtctgaatc
    20161 ttttccattg cttctttcat gatcgcaact tctttcatca tgcgtgagta agtcttttca
    20221 ttcaacgatt ggggaccgtc tgaccaagca tttgcaggat caggatggat ctctacgatc
    20281 atgccatctg ctccgcttgc cacacccgca cgagccattg gtggtacaag ttcccaaatt
    20341 cctgtaccat gacttggatc aacaatcaca gggaaatgag ttaatttttt catcaatggg
    20401 acagcactta aatcaaacgt attacgtgtc gctgtttcgt aagtccgaat cccacgttcg
    20461 ataaaaatga caggagattt gtcttcgact gcaatgtatt ctgcagcatt aagccattca
    20521 ttgatcgtac cggaaattcc acgtttcaat ccaacaggtt tacctgtttt accgacagca
    20581 gatagcagtt taaaattttg catattacgt gcgccaatct gtaggatatc gctgtactca
    20641 gccaccatat cgatatgccc ttcatccatc acttcagtaa tcactttcat tccaaattca
    20701 tcagccgctt gacggatgta tttcaatcct tcttcttcta aaccttggaa agcatatgga
    20761 gaagtacgtg gtttgaaggc accacctcgc agaatttttg cgcccccggc tttggccatt
    20821 cgcgcacatt ctctgatttg gtctaatcct tcgatagaac aaggaccagc catcgtcacg
    20881 aaactgccgt caccaatttt tactccgtct acatccacga ctgtattgcc aggatggaat
    20941 tctcgagaag tcaatttgta tgtgtttaaa atacgcacag cattttctac tccttcatag
    21001 cgtgtaaatg ctccttcttg taaacttcgc gtatcacctt ttagtccaat cactactcgt
    21061 tctgttcctt gatcgattga gactttgaat ccttcttttt cgatatgatc gacgactttt
    21121 tttatttgtt cttccgttgc ttcttttttc ataattacta tcattgtttt tcccgctttc
    21181 ttttgtttac ttatctatct tggctgattt tctctacttt ttcaaggtgg ttttacatta
    21241 attcctacta aatgaccgtg tcctgttgtt ctcattttcg ctccttcttt cctacttatg
    21301 acccagataa tcaacaaaaa aagatgtccc tgtaggaaat tgcctctaca gtgaacatct
    21361 tcaacgagcc ttaaaaagcg ctgcaaaaat ataaaatagc cactatagat gaatttctct
    21421 acgtggctgt aagtcgtgtt taaaaatctt tagccatcat agatacaaac ctggtttgtt
    21481 tgtacccacg aagtcatgaa tacaaaccta tctaaaatag ctaaagtaat acgtattcag
    21541 ttttgtaagt tttctagatt tcataaaaaa tcgctccaaa ctgatgtaag aattgtacct
    21601 agtatagaca taaaaaaatc gactgtcaat catttttatg aaactttttt taattttctg
    21661 atagttaact ttgtttttca gaaaaataac aattggtttt attgaagaaa atagtcatga
    21721 acaaaagtat ctgagaactt ttttactctc ttgttcatga catatagaat aaagcagctt
    21781 tgtcttgtaa actccgtttt tcaaataata atctaaagat tgctactgaa taataaagcc
    21841 gatttcatgg tcctcttcgc tgctgattcg gtaaggtgac tcaacatccg ctccccagct
    21901 attgataccc ccgactcctc ttacttttgc aaaaatcgta agaaccgttc gtctttctgg
    21961 cggtagttct tctatatgtg ttgcctgttc cagttcttct gctttgaatg gtaaagcgga
    22021 aaaagcaaat ggcgtatcct gctgttcaaa tcgcaacgaa aaatcttctt gatctttatc
    22081 cgtattatcc aacgtttgat ttcttgttag ttctacccat ttcgtttcca tatgcatgcc
    22141 gcattcttgg ggaacaaggt atggggaaac ggggagtcct gccactttat aaataccttc
    22201 gacaccacca gccatccgat ccggatatgt ttcccctgat aggccttcat actcaaaaaa
    22261 ttttgctttc gttggcataa tgaaccttaa acccaatgcg ggtaattccg gtaatccttt
    22321 ttgtccataa taatgcatat tgacaagcat tttaccctct ccagcgattt ggtaggaaat
    22381 tgtcacttgg gtttttggta ctgtgttgat ttccagtgta aaaatgattt caaccgtttc
    22441 agcgtattca ttacttgaat attgattatt tactggagca atcggcaaat cgatcttttt
    22501 attgtccacc agtacttcta tttctttgac ttttggatac aatccggctc ctaaccacat
    22561 accggattta aatccaaatc cgctacctct gtcattatcg gtcgttgctc gccaaaaaac
    22621 tggaagtgtt tcccggtata gccattcttt tccgttttta ttgagcgatt ccagtccgcc
    22681 tcttgtataa gaaaaaatat aatgcgtatt ccccgatttg acacctaatg tacagtcgcc
    22741 gaagacgatt gcaacttttt ccgtatccat atgactttta tttactgtat ttttcataat
    22801 aatatcttac ctcctgcatg gcgggttttt cttgtccatc tgcaaaaacg atcccattcc
    22861 ctgagaattc atagtcactt ggtttatcgt caaagtcacc gccatagcgc atcacttctc
    22921 tgcctgtgat tggatcagtc acttggatcg cctgatcttt aaaatcccat atatagcctc
    22981 cttggtacat ttcataacga tcaagcaacg tcatgtaaga atccattcca cctaacgaat
    23041 tccccatgtc atgcatatat tcacataaga tgaacggttt ttccgcttta ttttcaaggt
    23101 agtcaatgat ctcttctggt ggcgcataca tgcagctttt tacatctgaa atcgaatctt
    23161 cgaatgctgg atttggaaaa ttcccttcat aatggacaag tcgatcgggg tctacttttt
    23221 tgaagtaatc gttcatttgt cgaatgtttt cttccgcata agattcattt ccaagagacc
    23281 aaaaaagaat acttggatgg ttttttaatg tttcgaaatt cgtttttgct cgatcaagaa
    23341 cagccgcctg ccactgaggt actgcacctg gtacgttgta agaaggctca aatgcgccca
    23401 ttttttgcca tgagccatgg gattcgaggt tcgtttccgc catcacatgg attcctgctt
    23461 ggtcgcataa ataataccaa gtgatctggt tggggtaatg agatgtccgt acgccgttga
    23521 tctttgcatt ttttatgata gccaaatctt tttccatatc ttctatagtg atggcgcgtc
    23581 cttttttcgg atgccactca tgtcgattta ccccgttgat aatcatccgt tttccattga
    23641 agtagatgat tttatctttg atttcgattt tacgaaaacc gaaggaatag tcaatatact
    23701 ccgttactct tttttcttcg tctatcgtct ccaattcaag cttatataaa ttgggctgaa
    23761 aatgccccca cagtgccaca ttttcaaatc catcgatgcg aatcgtcatt tgctctttta
    23821 acggatattg ctgttgatag atttccttcc catcaggatc tagtatcgct acattcagct
    23881 gactgttttt ggctacttgc tcaaaagaca aatctacttc aagtttgcca ttttgacatt
    23941 tgtcatctaa gcgaggtttg atccaaagat cttctaaatg gttttgtcct cgagcaacta
    24001 agaagacatc tctgaagatc ccaaaaaatc ggaaaaagtc ctgatcttcc aagaatgcag
    24061 ctgtacttct tttgtaaacc tccacagcta gaatattttc ttcttccaaa taaggtgtta
    24121 aatcaaattc agacggagtg aacgaatctt cggcataccc gataaaatga ccattcaacc
    24181 aaataaacat tgcttgttct acaccagcaa aatgaatcga gatttgtttt ccctttagac
    24241 cttcttctaa tcgaaaagtc gtcaaatacg aaccaaccgg attgtcttta gcagctgaaa
    24301 agatcccttc cgcctctttc tcagggcttg tcgtgaaagg gggacggcga aatacatgtc
    24361 cctcccacgg atacatcgta ttgatgtaat ggatcttgtc ataatttgct aattcaatat
    24421 gactaggaac agtgatttca tcaaaagaac aggcatcaaa atctttttta taaaatgttt
    24481 ttggtcgtac cgaaggattt ggcgaataac aaaaacgcca tgatccattt aaagactgtt
    24541 taagggagga tgtggtttct acttcttccc ttgttgcata acaaacatga tcgctatgtg
    24601 catttgattg gttcactcta aaaacttgtg gatcatctaa ccattttata tttgctttca
    24661 tacttttttc cttctctctc ataacttttt gaaatgaagc agttctgttt ggaaatcacc
    24721 ttgaaaatcg gggaagtaaa gtccaactgt catcaattcg gcccccgaaa atatccgctt
    24781 cgaggtctgt tcctgataaa gtgcctcatc atctaacccc atcagatata cttcatggaa
    24841 cgctggttga gctgaagcta gtatcctccc taaaaacaca atagcttcat cttgtttagg
    24901 agacacaaac atccatgcgg caatattttc ttcaaaagga ctcgccaaac gataataatg
    24961 gccatactgg atcaccggac gaatcgtttg ataggatata atttggtctt ttacttgctt
    25021 ttcttcttca ggagacagct ttgtcaaatc cagttcataa ccaaaaacag cgctcatagc
    25081 tgtttctcct cttgttttca acgaagtaga tctgtcggtc tgatgatttg gtacagctga
    25141 tacatgagct gtgatggacg aaatcggata agcaaggctt gttccatatt ggattttcat
    25201 acgctccact gcatccgtgt tatcacttgt ccatgactgc ggcatataat aaataaaccc
    25261 ggcatcaaac cgtccacctc caccagaaca gccttcccat aagatttccg gataatcagt
    25321 tgtcaaatgt tcaagtagtt cataaagccc gagcatataa cgatgcgcta cttctccttg
    25381 tctctgtggg tcaagggtaa tcgaatagac atctgaaagc gaacggttca tatcccattt
    25441 gatgtagtca agaggaatcg tatctaaaat ctttctcatt tgtttctcaa tcgtctgccg
    25501 aacatctaac cttgtaaaat ccagtacatg ttgtgatctg gaagcagaag gcattctacc
    25561 tggctcctgc ataagaaaat caggatgtgt tcgatacagt tcagaatcaa ccgagatcat
    25621 ttcaggttca aaccataaac caaatttcaa tcctttgcta tgagcataat ctgctatttc
    25681 acgtaatcca tttgtcaact tgccttcata ctcgaaccag tctcctaatg aagaattgtc
    25741 cgcatctctt tttccaaacc agccatcatc taatacgaac atttcgatgc ctagctcctt
    25801 tgcttcatca atgatcgcct tgattttttc actattgaag tcaaagtaag tggcttccca
    25861 gttattgacc agaatcggcc gttcagcaaa ttgatgacga cctcttgcga ttctttcacg
    25921 tagcaactca tggtggatct gactcatttt gttcaatccc tgacttgagt aagaaaggat
    25981 catttcaggt gtttgaaaag actggcctgc attcaattcc cacgaaaaac gatggctgtt
    26041 gatcccaccg acgactctca attgattgat ctgatctttt tcaagttcga aagaatggtt
    26101 gccggaataa acaaattgaa gtccgatcgc ttctccagta ttttctgtcg tatgatgatg
    26161 aactaaagca ataaagttat tcatatggtg actgctcgtt cctcgacggc tttcaaatac
    26221 ttttgttcca gataaaacag attgccgtga aatctgtctt tcattgacat gtgctcctgg
    26281 caaagcaatg acttcatcaa atcgcctagt atgggcaaag tctagctgga aactagccgc
    26341 tttttctagt ttgattgttt ctccggtttc atttcttatc tttacagatc gtgtgatcac
    26401 tgctctatca gtaaatatgg tatagaacaa atcgaaataa atcgctgttt ctctatcctt
    26461 aagtgaaatc accaacgttt gtgcctctga cttgtccatc acataagttt gaggcaagcc
    26521 ttcgatctct ggcttcccat ctgtaatata atggctgtca tatctcagat ccagtaagtc
    26581 tgatccattc ttgcgctgaa tgatcgatgc gggcgttcga aagtccatgc tgccatgaga
    26641 agagtattct tgcggtagtg tatctttcga cagagaccgg tcaggattta agggaacatt
    26701 tcctgaaaat ccacgatctc ttcggggata atttttattg tctttgtact gcttgactgg
    26761 tttgccaaaa taaatatgcg ccaatacatt gctttcttct atctttatca gataagaaag
    26821 aaatgtattt cgtaaatgga agactcggct cttttcatca aataagatga aatttttatc
    26881 tgtttttcta tgcgtaatat ccatcatttc actcccaaca aaacggaaac cgtttacttt
    26941 tttttataat tcctgtatac tgtttactaa acaattttgt caataaaaat tttttatttt
    27001 tttgaggagt gtgtaaaaat ggttggaatt agagatgtcg cacgaaaggc aaatgtctct
    27061 cctgctacag tttcccgtgt gttgaataac gatcagacga tccatgtggc tcagactact
    27121 cggcaacgga tagtagaggc agctgctgcg ttggattatg acatcagtac tcgtaaatat
    27181 atcaaaaaga gaatgccttc gattggtgtg atctctacga tcggcaaagc gagcgaagaa
    27241 caggatatct attacaaaca tttgcgagta gggatggaag aagaagctcg acgtctgcat
    27301 ttagggatga atcgaatcta taatctatct gataatccta aacaatggga agatctagat
    27361 cagttaggtg cggtgatcgt tgttgggact gttacgaaag aatcgattac cgccttgtta
    27421 aaacaaaaca tgcaaatagt cgtcgtggat aaccctgaca tccagcaaga ggtcgatatg
    27481 gtgtatgcag atcttgaacg gatgactaaa accgtactgg aattgttctt agaaaatggt
    27541 cataaaagaa tagcctatat cgggggatat aaagtcgata tggatgaatt cggtgggaag
    27601 cagatttcta taaatgaaaa gaggatgcgt gcctatcagc attttatgat cgatcatcac
    27661 ttagaaaaat atatgtctta tcatctaggt ggctggacag aaaaacaagg tgaggtactt
    27721 gcgactaatc tattagaaaa tgaatcccct cttcctactg ccattcttgt cgggagcgat
    27781 ccaatggcaa ttggtgtcta tcgggcattg aaacaaaaaa atatccaaat tggagaagag
    27841 attgttgtag caagctttga taatatcgag acaatcgcaa acctctcccc tggcttgacc
    27901 agtgttcaaa tcaatgcgaa atcaattggg caagcagctg ttcgaatggc attggagcga
    27961 attgacggta tacgggacga accaatcatt ttgacttatc ctgcacgatt gattgttagg
    28021 gaaagtttta tcccaagaac aaaaaggtat tgaaagagag gttgtgaaaa gccgcttcgt
    28081 ttcttcatac tcaaaacgaa acggcttttt cacaacctct tacttatact tattcacaaa
    28141 atccaatgtc tgctggtaac aattttgcga ttcttttagc gtgtaatcaa attggtattc
    28201 atgggtaatc tctttttttg tatctgtata aaacaaggat tgcacgggta cctttaattc
    28261 tgtcaaccga ttttctaatg cttgaccttg ctcctggaat gagtatgcat ttccgtcagt
    28321 tatatacgtt ggcggaaatt ccttagaaac atggtcagcc acactagctt ctttcaattg
    28381 ctcactcgtt ttccaatctt ttgttccaat caacgaccac gcaacggttt tgacgaaaaa
    28441 cttcataaat cgatcatccg aatgctgctg tgctgttagc ttcaaatcaa caggtccgca
    28501 ataagaaatg gttcctttca gactatcttt tggaagtagc tgtttgattt tcatttgttt
    28561 agcatacgca tcattcgttt gtatagctgc atattgcaat gcgatttgtg aacctgcact
    28621 atctccacca aaaaataatt gttccatgtc tagcaatttg tcgtcttttt cttcagctaa
    28681 taaatctttg atcagttcat tcacttgaag aacttgatta gggtattctg aatcaggcgc
    28741 taattcataa ttcatcgcaa ccactgcgat gttggcgtct gaaactaatt ttgtcgcaaa
    28801 ttctttgaca cccgatttat ctccgccgac gaatcctcca ccatgtaccc aaaatagaac
    28861 aggaacaggc cccttgctgt tttttggata gtagatgtca taagtattct ctttatactt
    28921 ggactcatac gtcaaatctg tttttttcgc cacgtttttt tctgcttgat cgaacgtttt
    28981 tttatcagtg atttgaacag tatttgaaaa catatggttg atcaagaatg ctccaggtct
    29041 gggggaaagc tggaaggcaa gaaagattgc aaacgcgatc ccaagaatga ttccgaagaa
    29101 ccatccgata aatttaagaa ttttcttttt cataaggctc cctcagtagt tagtattaag
    29161 cattctgatt ataccatagt gttatttcct atcaagctct cctagatgat ttaatgattt
    29221 tccccaaact tcttctgcaa tgcttttgac aaaagaaatt ttttccattg ttcttcaaac
    29281 aaaacatttt cttcttctgt tgaagcaaat ccacattgag gacttaagca caaacgatcc
    29341 aaaggcagat atcgtgtcgc ttcgtagatc cggtcaatca cttgctggtg ctcttccatt
    29401 tcgccatttt tcgttacagt caaaatctaa gacaactaat ttatcttcag agactttctc
    29461 taaaagaaca aaactcccag cacgttcact atcgtattct aaataatagg cacggacatt
    29521 ttcttgagta aaataatggg tctgctacgt cgtcatcccc cctgatgccg ccaaaatcga
    29581 ataataattt ccgcgtcaaa catgtatatt tagtgttgaa tcatttgaga atatgaaaat
    29641 aaaaatcttt ttgatcaatc agttaatcaa attgaaataa cgaaaaatct gagacagaat
    29701 gacgttcatt ctgacccaga tttgattttg cacaactcaa cagtccttat tggcaaatcg
    29761 ccaaaataat gtagactaac taaaaagact aagaaacaat aacaaaagtt aacacttctt
    29821 agtctttctt tagcacgtct atttattaaa gattttaggg ccttttctca tgtttttacg
    29881 atcattctta ggtgtttcca tttgtttgga tcggcctcca ccttgtttct ttttgatcaa
    29941 ttctttcatt ttttcttttt ggtccatttt tattctcctt taacgaatga agcgactaat
    30001 tcgatatgat gggtttgcgg gaaaagatct acaggctgaa ctttcttcac ggcataacct
    30061 gcttctgcaa ataacttagc atctcttgca aaagttgccg gattacatga gatatagacg
    30121 attcgttctg gtgacatttc gattgctgat tcaataaaat gatgatctaa tccttttcgt
    30181 ggagggtcaa ctacgatcac agatggtttg atcccttttt cttgccattt tttcataact
    30241 ttttctgctt ttccgacttc ataatgaaca ttttcgattt tattatttaa agcattgaac
    30301 tgtgcatctt caattgcttc tggaataact tccatcccat acaccttatc cactctgtct
    30361 gctaaagaca agccaatcgt acctattcct gaataagcgt cgatcacaat gtctttttta
    30421 tctaactcgg caaactcgat ggctgtttgg tacagatact ctgcttgttg agtatttact
    30481 tgataaaatg actttgctga gattcgatag gtttttccta atagctgatc ttcgatatag
    30541 tctctgccat ataaaacttt ttctttgtct cctaaaatca catttgtttt ttcttcattg
    30601 atattttgga tgaccgaaac cacttctggc aattcttcat gaatagcttc agcaatttcc
    30661 ttggatttaa agaatttttc tttacgagta actaaaacga ccatcatttc atgggaataa
    30721 tgaccacgac ggataatgat gtgacgaagc tgtccttcat ttttttcttc attatatcct
    30781 cgtacttgga accgttgcaa gatatctctg actactttga ttgcttgatc gatgacagga
    30841 tcttggatat aaaaatcttc gatagggact agatcatggc tattcttttt gtaaaaaccg
    30901 gtggctaact gtccatcgat acggcgaaca gggatctgtg ctttattacg gtagccgaat
    30961 ggttctgcca ttccgaccgt tggaagtaca ggaacttctg gcatcttagc aatcttcgcc
    31021 attacatgct ctacttgttt ttgtttgaag acaagctgtt gttcatactt caaatgggct
    31081 aaaggtgcga tacctatgcg aagtaatgca ttgttttcta caggctgacg atcaggtgat
    31141 tgtgtaataa atgtttcgac ttttccatat ccaaacttat tgcctgcttt tactactagt
    31201 atttctactt cttctccagg gagtgcattt tcgataaata atggataacc atcgattttt
    31261 gctaccccca ttccttcata actcaagtcg acgatttcga ctgtatatcg ttcgtttttc
    31321 tttactattt gctgttctgt catattttgc tcctttaagc ctatttttca atcctactga
    31381 actctactat aaatcagcta attacacaac taaaaccggc actgacctta ctacgttcag
    31441 caccggcttt tgattaattc ttttgattag gtgtttcgtc tgctattttt ccgtcaccgt
    31501 cgatatcttc atccgttaaa cgttcgactt cttttacgaa ttctttgctg acaacctcta
    31561 attcttcttc atctgtacct gtgattgctt catcaggaat ctgatcggta ttggcaaaga
    31621 actcaatgtg ttgatgaaga ttttggaaat gcatcggtgc ttccccgccg tattcaccat
    31681 ctaagttgat cattactggt cgattgatat catcttctgt ttcaacgaac aaactgcttg
    31741 ttttggtata gattattctt ggatcatcga catgtcgacc gccattcagc atgagtgctg
    31801 caatatgcaa gatctcaaag atatttgctg tcttcacaat gattaaagaa aacttcccat
    31861 catccaattt ggcatctggc gcgatctgtt cgaatcctcc aacagagttc gtcagcccta
    31921 ggaaaaacat cgaagcattt ccgatatatt ccccttcatc atacttcaag cgcattttga
    31981 ttggctttac tcgagggagc atctctgctc ctttcgcaag ataagcaaga taaccaaaaa
    32041 tactctttag ttctgatgga acttcataag tcaattctgt caaatagcca cctgcagcga
    32101 tattgatgaa gtaactgtta tcagaaaggc cgatgtccat ttttacggtt tggtgttttt
    32161 ttatcacttc tgctgctgct ttaatattat ctctaggaat ttttaatgct cgagcatagt
    32221 cgttcgttgt accagctggg atgatggcca ttttaggacg gtgttcaagc ggagcgattc
    32281 cattaaccac ttcgttgatt gtgccatcgc caccagctgc cactactaga tcaaaaccta
    32341 gttctgcgac tctacatgct tcattcttgg ctgaatctgg ttctggtgta gttgcatagg
    32401 cgctggcttc aaatcctgct tcttctaatg cctgtaggat atccgccaaa ttttttttca
    32461 ataattcttt tcccgaggtg gggttataaa ttacgcgtgc ttttttcatt ttcagcctct
    32521 atcgtttcgc taattcatct ttaagtagct tattcacgac accaggattt gcttgtcctt
    32581 tagttgcttt catgatttga ccgactagga agccaaccgc acgatctttt ccatttttga
    32641 aatcatcgac agattgttgg ttgttatcca aaatttcatt aatgattggc agtagtttgt
    32701 tcggatcaga taattgcacc caaccatttt tttcaactac ttcttgggct tctccgccat
    32761 ttgtgatcaa ttcacggaag acttttttgg cgatttttga gctgatcgtt ccatcggcga
    32821 tcaaacgaat cattcctgct aagttctcag gtgtcaattt tgtctcagct aattccagtt
    32881 tctcactgtt caagtaagca gaaacttcac ccatcaacca gttagatgct tgcttggcat
    32941 ctgcaccatt ttccaaaaca gcttcaaaaa aatcagacat ttcttttgta agtgtcaata
    33001 ccattgcgtc atactctgga agtccaaact cacggatata gcgttcgcga cgagaagctg
    33061 gcatctcagg caaactagct tttacttttt gaatccattc gtcatcgatc acgaatttcg
    33121 ggatatcagg ctctgggaag taacgataat cactagaccc ttctttgaca cgcatcaaaa
    33181 ctgttttatt cgttgtttcg tcaaaacggc gtgtttcttg ttggatttct cctcctgaaa
    33241 gaagaacttt tgcttgacgt ttttcttcaa aagctaaacc ttttttcacg aaagataaag
    33301 agttcaagtt tttcaattct gctttcgtac cgaactcttc ttgtccataa gggcgaagag
    33361 aaatattggc atcacagcgc atagagcctt cttccatttt cacatcgctg acttctgtaa
    33421 attggataat tgatcgcaat gcttctagat aagcgtatgc ttcttctggt gaacgcatat
    33481 cagcttcaga aacgatttcg atcaaaggcg tgccttgtcg gttcaaatca acgtaagaat
    33541 aaccgccaat accatgcatg ttttttccag catcttcttc taaatggaca cgttcgatcc
    33601 ggattttttt ctttttacct tctacttcga tttcgatcca tccgtcatga ccgattggtt
    33661 gatcaaattg ggaaatttga tatgcttttg gattatctgg gtaaaagtaa tttttccggt
    33721 caaaatgagt atctttagag atttcacagt ttaatgccaa agctgctttc atcccgaatt
    33781 ccagcgcagc tttattcatt actggcagca cgcctggata accccagtcg atcacgtttg
    33841 tattgctgtt tggttctgca ccaaaatgag ctggcgctgg agagaaaatt tttgagttgg
    33901 tttttaactc gacgtggact tctagtccaa tgactgtttc aaaattcatt cgtctttccc
    33961 tcctaaaata gctggttgtt gtttatggaa ttctgttgct tgttcaaacg catatgccgc
    34021 ttgatacatc gttttttcat caaaataatt accgatgatc tgcaatccaa ctggtaatcc
    34081 ttctgataaa cctgccggta cagacatacc tggaagtcca gccaagttga cagggatcgt
    34141 taagatgtca ctcatgtaca ttgtgattgg atcgttaatg ttctcaccga ttccgaatgc
    34201 aactgttggt gaagatggcc cgatgatcaa gtcataatct gcaaagactt tttcaaaatc
    34261 tcgtttgatc aatgtacgga cttgtcctgc ttttttgaag taagcgtcat aataacccgc
    34321 gcttaaggag aatgtaccta acatgatacg gcgttttact tcttcaccga atccttctga
    34381 acgtgagttg acatatacat catctaatga tttcacattt tcagagcgat aaccgtagcg
    34441 gataccatcg aatcgttgca aattggaact tgcttctgat gaggcaatga tataataaac
    34501 agccacaccg tattttgaat gaggcaagct gacttcttcc acaacagcac ctaatgaacg
    34561 gaatgtttct gctgctttca atacagcttc ttttacgcca ggggccacac cttcgcctaa
    34621 gtattcttta ggtaaagcaa tcttcattcc tttgatgtcg cctgtcagtc cctctgcaaa
    34681 atcaggaact gaaacgcctg aagaagtacc gtctttttcg tcataaccgc tgatagctgt
    34741 caatgctaat gcattatctt tcaccgtacg ggtcattggt ccgatttggt caagagatga
    34801 agcaaaggca atcaaaccaa aacgtgagac acggccataa gtaggtttca tccctacgat
    34861 gccgttaaaa gctgctggtt ggcggatact tcccccagta tcactaccta aagaaactgg
    34921 aatttgtcca gctgcaactg ctgctgcaga accaccagaa gagccaccag gtacttttgt
    34981 tgggtcccaa gcattttttg ttttcttgaa ataagaagtt tctgtacttc cacccatagc
    35041 aaattcatcc atgtttagct taccaacagg gatcatatct gcttgataga ttttatccat
    35101 gaccgttgca tcataaattg gttcaaaatt gtaaaggatc ttagatgcag cggttgtcaa
    35161 gatatctttt gttacgatat tatccttgat accaattgga ataccagcaa ggacgttgct
    35221 ttcatcaatc cctttttcat ctaaagcttt tgcctgttcc aatgcttttt cttcgttcaa
    35281 tgtaatgaat gcctcgacct caggctctgt ttctttgatt cgttcaaatg ttgtttttgt
    35341 caaatcttgt acagtgattt ctttcgatac aagcatatga tgcagttctt ctagagaacg
    35401 attgtgtaat tctgtcatta tgcgccagcc tccccattat cgatgattgc gggtactttg
    35461 ataaagccgt cttctgtttc cggcacattt ttcaataatt catcgcggtt ccatccagct
    35521 tgcgcccgat cttgtcgcat cacgtttact gtttcaacca cattcgacgt aaatggaaca
    35581 ccttccgtat ctacttcttc cagcatttca accatatcga tgattttacc taattggtcg
    35641 gtaaaacttg caagttcttc atctgcgaac gcaagttttg ctaatttggc aacgtgtttc
    35701 acttgttctt cactaatcgc catactaccc cttctttcta aacgagttaa aaactttgct
    35761 ctctatttta acacaagagt gccgtgtctg aaattgttta ttgaaatttg tctgaaaaaa
    35821 ctcatttttc attcttctac tgagcgactt ttagccaatg catctgccat ttgatcttct
    35881 gtccaaactt cgattcctaa ttcttgtgct ttggtcagct tgctgccagc atcttctcct
    35941 gctaccacga tatccgtttt tttcgatacg ctaccagtca ctttcccgcc aagattttcg
    36001 atcgtctctt ttgcttcttc acgagtaaat cgtgttagtt taccagtaag gactactgtt
    36061 ttttctttaa aaggagactc gacttcttgc aattgggcat ttcgaagccc tttgtattcg
    36121 aaattgacgc ctgcttgttt taattcattc atcaattcat ggacttcttc gttactgaaa
    36181 taagtgacta cactgtcggc aatgatatca ccgatcgtat caagcgcaat aatcgactca
    36241 tagtcacttt tactcaatgt ttctagatca ccgaaatgtt ctgctaaaat ttttgctgct
    36301 ttcgctccga catgtcggat tcctaacccg aaaatcaacc gctcgaccga attatctttg
    36361 ctgttgtcga ttgctgtcaa aatattattt gctgattttt cttttatttt gtccaacgtc
    36421 aataactctt cttctgtcaa tttgtaaaga tcagcaacat ctgctactag ttttttatca
    36481 tacatctgtt ctagtacgcg cggccccaac ccatcgatat tcatcgcatt tcttgaaaca
    36541 aagtggttca aaccttcttt catttgagca gggcatttag gattgatgca ccgtaaggct
    36601 acttcttcat ccaaatggac aagttcactt ccacaaactg gacaatgtgt aggcaattgg
    36661 tattcttcgc tgtctttagg tcgtttatct aacacgactt gcgaaacttc tgggatgatg
    36721 tctcccgctt tataaatcag aactgtatct ttcaagcgga tatccttcaa cttaatataa
    36781 tcaccgttat gcaggctggc acggcttact gtcgttcctg ctactcggac tggtgtcatg
    36841 atagctgttg gcgttactac ccctgttcga ccgactgtcc attcgatgtt ttcgattagc
    36901 gtttcaactt cttctggcgg aaacttgtaa gctgctgccc atctcggtgc tttgatagta
    36961 aaaccaagtt gatcttgtag cgagaattca ttcactttga tgacgattcc atcgatttca
    37021 tagggcaaat ccacacgttt gtcatgatat tcttcaatgt atgaccacac ttcatcaatc
    37081 gaatgacata gacgtttttc ccgattcgtg tggaatccaa ttttttctag ctcttctagc
    37141 gcatcatact gggtttttgc ttgcatagga ccgaaatcag ctactgtgta taaaaaagtg
    37201 tccagatttc ttttcgctgt gattttagaa tctaactgac gcaaagaacc agctgcggcg
    37261 ttccgaggat tcgcaaagat atcttttccc tctgcttctc tgtcttggtt caattggaca
    37321 aatgaccgtt ttggcatgaa acattcgcct cttacttcga tgttcattgg ttcttttaat
    37381 ttgattggga ccgaccggac agtttttagg ttttcagtga tgttttctcc tacagttcca
    37441 tccccgcgag tcgcacctct cacgaaattt ccatcttcat aacgcaaaga aacggaaagt
    37501 ccatctattt ttagttcaca gcaatagtca actacacgtc ccactgcttt ttgtacacgt
    37561 tgatcaaaag ctatcagctc ttctttgctg aaaacgtcgt tcaaactgta aagcggaata
    37621 tcatgagtga ctttttcaaa accttctaat acttttccgc ctactcgttg agtgggagaa
    37681 tcagacgtga tcaaatcagg atattgttcc tcgattgcta ctaattctgc gtattcttta
    37741 tcataaacat agtcttccac tgttggttta tcttctacgt agtattcgcg agaccattgg
    37801 ttcagtcttg tacgaagttc ttctgctcgt ttagcagctt cgtcaatcgt catttcatgt
    37861 tccatcattt accctccact actaagcttt ttcaattggc gcaaaggcag ccaaaagacg
    37921 ttttactcct tgacttggga aagccacatc tagttctaga tccttcgacg tcccgcttac
    37981 tcggacgact gttcctagac cccatttttt gtgtttgact ttatctccag gtttccagct
    38041 gttattttcc cctccagtag cacttttaga gggaacaacc gctgtctctg gctgtttata
    38101 gctatatgct gtttttttag cgaatacagg cgttttttta ggcgtaggac gcatgccttc
    38161 gatttccagt aactcctgat cgatttcttc tacaaaacga gaaggtcggt tatattgcgt
    38221 ccgtccatat aatgttctgg agaaagcatt tgttaaatac aacgcttctt ctgctcgcgt
    38281 gatccccaca tatgcgagac ggcgttcttc ctccagttcg ctttcttcca tcaatgctcg
    38341 agataaagga aaaaccccct cttctagacc aatcaggaat acaactggaa attctaatcc
    38401 tttggctgca tgcaaagtca tcaatgtcac ttgggaagca tcttcttcta aattgtcaat
    38461 gtcggaaaca agtgccagat catttaagaa gaccgttagt ttttcttctg gtgcatcagc
    38521 gtcttcttca ttttgctgtt cgaattgttt gtcgaattct tgtgtgaccg ttaaaaattc
    38581 ctccaagttt tcgatgcgtg cttgtgcttc taatgtattt tggattttta agtcttctag
    38641 atatccgcta cgatccaaaa cctctttcgt caattctgtc actgtcaagt atgggatcat
    38701 ctgagtgact tcttggatca tctctccaaa tgcacctaat tgctgtcctg cttttccacc
    38761 gatatttgcc agatccacat tttgcgctgc ttcaagcagt ggccattcat gaagagaagc
    38821 aaaactgcgt agtttttcga tagatcctgg tccgatgcct cgtttgggcg aattaacgat
    38881 acgctcaaaa ctgattgaat cttgaggatt taccagcaca ttcaaatacg ctaaaatatc
    38941 tttgatttct ttacgatcgt agaacttgtg ccctccaacc attttataag gaatatttgc
    39001 tttcaacaga gtttcttcca ttacacgaga ttgtgcgttc gtccggtaca agatggcaaa
    39061 gtcgccgtaa ttccgatgat tgcttcgaat ctcttcttgc atccggtcta cgataaaacg
    39121 ggtttcgtct cgttcattat ctgcacggta gtaagtgatc ttgtttcctt ctttgttttc
    39181 tgtccacaag ttttttggtt ttcgattgct attgttttca atgacttggt ttgctgcgct
    39241 aaggatgttt ttcgtggagc gatagttttg ttctagcaaa attactgcag catctggata
    39301 atctttttca aaatccaaga tgttctgcat atctgcaccg cgccagccgt aaatactttg
    39361 atctgcatct cccacgacgc acaggttcct aaatctacct gccaataaat tgactagcgt
    39421 atactgtgcg tgatttgtat cttggtactc atctacatga atataatgga atttgttttg
    39481 ataatacgtg agtgaatcag gatgttcttc aaataatcga atcgtattca tgatcaggtc
    39541 gtcaaagtcc atacattgat tatattgaag ctctttttgg taagcagcat aacattttgc
    39601 cgcaatctct tcgtaataac tgccttgcat ttttgcaaaa tcctgagggg tctgcaggct
    39661 gttttttgct tgagagattg ttcctaatat acttcgagga tcatattttt tcggatcaat
    39721 gttcagttct tttagtatcc gtttcatcaa ggtcagctgt tcagaagaat cgatgattgt
    39781 aaagttccgg ttatacccga taaaatcaac atctcttctt aaaatacgca cacacatcga
    39841 gtgaaaagtc gatacccaga catcttcgcc tccagatgcg agaatcgcat tgacacgttc
    39901 tttcatttct tttgcagcct tattggtaaa agtaatcgct aggatgttcc aaggattgac
    39961 ttctttttcc tcaatcaaat aggcaatgcg gtgtgtcagc actctcgtct ttccacttcc
    40021 tgcacctgcc attagcagta atggtccgtc agtgtgaaga acagcttctt tctgacgggg
    40081 gttcatcccg tttaataatt cagctttgga tgacattaac aacatccttt cttttatcaa
    40141 tcttgttaat tatagcattt tcttggcttt cattaaacta gctagttcaa aatcatttgt
    40201 ttctttttat ggatttttcc ttgtcaattc gttgatttcg cgctaaatta aaagaaagcg
    40261 aggcgtttga atggaaaaaa aaggaaaaat caagaaatta gataagactc agatatattt
    40321 tattctaaaa ggaatatttg ttggactgct gacaggaatc gtcgttagcc tgtttcgatt
    40381 atctatcgaa aagctaagcg atttagttcg aagtatctat gaaatgagtc gggaacagcc
    40441 gatttactta attggcctag ctatttgctg catccttgca gcatttttcg tgggttatct
    40501 ggtcaaaaat gaaccggata tcaagggaag cgggattcca caagtagtgg gacagcttcg
    40561 cggggaatta tcaatgaact ggttctctgt tttatggaaa aagttcattg gcggtgtact
    40621 ttcagttggt gcgggccttt ttctaggtag agaaggacct tctatacagc ttggcgcatc
    40681 cattggacaa ggagctggac aattgtttcg gagtccatct tcagaagaaa agattttaat
    40741 ttctagcggt gcaagtagcg gacttgcagc agcattcaat gctcctatcg caggattact
    40801 ctttgtttta gaagaaatcc atcactcctt ttctccactt gtttggctga catcatttgc
    40861 ttcagcaatc actgctaact tcgtctctct ttactttttc ggcttgagac ctgttttata
    40921 tctaggtgac cttccttctt tgccgttgaa atattatggt tccttagtga tcttaggagt
    40981 acttctaggc atcttaggtt ttatttatca gaatgtcttg ctggctttgc caaaatttta
    41041 caaccgattg cctttaccag cttattttca cgggttcgtt cctttcttgc tgattttgcc
    41101 aattggttat ttatggccta gtactctagg cggaggcaat caaatcgttt tagcttttgg
    41161 acatgcttcc ttgccaatca ttatgattat cggtttgttt gttcttcgat tcgttttttc
    41221 catgatttct tacggtgggg gtcttccagg ggggattttc cttccgatat tgacattggg
    41281 ggctttaatc ggtagctttt atggaaacat tatggttgat ttcgggatgg atccaatcta
    41341 catcaaggat tttgtcgtta ttgccatggc tggttatttc acagcgattg gaaaagcacc
    41401 gctgacagca attattttag tgacagaaat ggttggctct cttaatcatc tgatgccttt
    41461 aggattggct gctcttgttg cttatatcgt caatgacctt ctcggcggta atccaattta
    41521 cgaatcatta ttggaacgtc tacttggaaa tactcagacc gcctcactaa aaggtgcaag
    41581 gacaactttt gattttccag taacggcaga gagttcttta gacggattaa tggtacgaga
    41641 cttcaattgg cctaaaaata tgctgctaat ctctatacgc agaggaaatc aggaaatctt
    41701 gactcacggt gatacgatca tgaatgtagg agatattttg gttatcttga ctgatgaagc
    41761 aaacttgcca agaatcaagc aggaaatcga ggctaaatct tctatcacaa atttgaagca
    41821 atcattttaa cgaacatgga aaaactattt tacaacaact attcatctac actacttgat
    41881 tctatatgat tctataaaaa aagaagaggc tgggaaaacc cagcctcttc ttttttattt
    41941 ctatgcttct gctactgcag gagcttttct caataaacca taaatcacac cagatacgac
    42001 tgctccgata gcaataaaca ccaaatacat gaccgggtga ctcagtaaga atacaacgaa
    42061 aatcccgccg tgaggagcca gtaatttgat tccgaaagct ccgactaatc cgccagttaa
    42121 agcagaacca ataataaaac ttggaatggc acgaatcggg tcagctgctg caaatggaat
    42181 cgatccttcc gtgacaaacg atagtcccat cacgatgttc gtcaaaccag catcttgatc
    42241 tgttttgctg aatttattct taaacaaacg tgtagcaacg aaaattgcca atggaggtac
    42301 cattcctcca gccataacag aagccatcac gacacttccg ccagttgcaa cagtcgtagc
    42361 taaagttgct gtaccaaaca cataagcggc tttgttgatt ggaccgccta aatctgccgc
    42421 catcattcca gctaataatg caccaagtaa agcagcattc gaaccactca tacttgtcaa
    42481 gaaaccgttc aatgcatcat tgattgcttt catagggaca ttgaccagca acatcaagaa
    42541 accagtaatc agtaagccaa acactggata aaagaggatc gttttaattc catccaatga
    42601 ttttggtaag ttcttgaata atttacgtaa aaatacgatg acataaccag ctaagaatcc
    42661 accaatcagt gcacctaaga atcctgcacc gcctgtatta gctaatgcac cagcagcaaa
    42721 tccaacgatc aaaccagggc ggtcaccgat acttgaagca ataaatcctg ctaataccgg
    42781 cagcatgaaa ccaaatgcag cttgtccgat ttggttgaac cagctagcag cttgattgta
    42841 attccctaga tttgataatt gatcatgtgg cacgccaata aattggtcga tcatgaaaga
    42901 aagcgcaata gcgattcctc caccaataac gaaaggtaac atgtgtgata cgccgttcat
    42961 caaatctttg taaattcttt gtccgatagt accatccgca tttccttctt ctgaactgct
    43021 ttcttttcca tcaccatgga atactggtgc agtaccacta agggctagat tgatcaactc
    43081 ttctggttta cggataccat cactgacagg acgattgatc agttcttttc cgtcaaagcg
    43141 attcatctct acttttttgt ctgctgcaac gattacacct tctgcacggg cgatgtcttc
    43201 agcagtcaat cggtttttga ttccttctga accgttcgtt tcgactttga tctccacacc
    43261 catttctttc gcttttttct tcaaagcatc ttctgccatg taagtgtgag cgatccctgt
    43321 tggacaagct gtaacggcaa caacgaattt tctttctgga tgagcagaag cttctgcagc
    43381 ttgtgtttct tgttctgctt tttcttctgc ttctttttgc tcttcagctg tttggaacaa
    43441 gtcttggact tcttctggtg tatttgcttc ttttaatttt cctacgaaat ctgcatcaat
    43501 cagcaatcga gatagtgctg ctaatgcttg caaatgtgtg tcgtttgcgc cttctggagc
    43561 tgcgatcatg aaaaacagat aagttggctg tccgtctaag gcttcataat ctactccttt
    43621 ttggcttttt gcgaataaaa ctgttgcttc tttaactgca ctgtttttcg cgtgaggcat
    43681 ggcgattcca tcaccaagac ctgtagaagt ttgtgcttcg cgggctagaa ttccttcttt
    43741 atatgtttcg atatcggaaa tccggccggc atcaaacatt ttttggacca tttcatcgat
    43801 tgcgcctttt ttatcagtcg cttgcaaatc catgatcatc gcttctttga ccattaaatc
    43861 cttgatattc atgattatcc tccttgaaac taatcaattt ttgtgatttc aacttctggc
    43921 agcaactcat caatcaattc gcgagctgcc aagtcatcag aaaaagctgt tgcgcttccg
    43981 caagcaactc cccatttaaa ggcttcgatt ggatctttcg tacggctgta agccccaata
    44041 aagccagcaa tcattgaatc ccctgcacct actgaatttt tcaatgggcg aactaataca
    44101 ttcgttttat aagttccttg ttccgtgaag agcaaagcac cgtctccagc cattgagatc
    44161 agcacattct gtgccccttc agctagtaat tttttcccat acggaatgat ttcttctaca
    44221 gattggaagg ttgtgttgta aagctcagct aattcgtgat tgtttggttt gatcaacaac
    44281 ggtttcttaa caagtgcatt ttttaggtca tcacctgttg tatcaatcac gaaatctgca
    44341 cctttttctc gaatgatatc aatcagttct tgataaaatc cttttcgcag gctagctggc
    44401 gcgcttcctg acaatacgac gatatctcct tgtcctactg ttcctaatgc ttgcttcaac
    44461 tcatcgattt cttcatctga aatagatggg cctaagccat tgatctcagt ttcagtgtct
    44521 gattttagtt tgatattgat tcttgtatct tcttttacgg ttgtgaacaa agactggatt
    44581 tgttcttttt caagccactt cgaaataaat tcgccagtga accctcctaa aaaccctagt
    44641 gctgtagatt gagaatcgat ccgtttcaaa atacgggaaa cattgatccc ttttcctcca
    44701 ggtaacttga agtcttcctt cattcggttc aaatcgccta gttttaaccc atctacgcgt
    44761 acgatataat caattgatgg attaagtgtt actgtgtaaa tcattgtatt gcctccttaa
    44821 ttgttgtctt ttcacggaat tcattaacga attctaatgg acaacgctcg gttatgatcg
    44881 tggctgcttc caaaggtgca acagaggtga aggacaactg gttgaatttg gtatgatcaa
    44941 tcaatacaaa tgtctcttcg gaatttttca tggctaaacg tttaacagct gcctcttctg
    45001 gatccggagt cgtgaatcct tgttcaagat gggcaccgtt cattcccata aatgctttat
    45061 taaaatgaaa attttttagt tgttctatcg cattagatcc taaaacagca ttagttgcca
    45121 gctttatcgt tccacctaaa ataatggtag caagctccaa atcaactaaa tttgccgcat
    45181 gttgaacgga atttgtcact actgtgatct gttttccttg cagaaaagga atcatttcta
    45241 acgtagtaga gccagcgtct aaataaatga catcttcgtc attaatggtt tcagctgccg
    45301 atttggcgat ttgctgtttt tcgtgaacgt ttttgagtga tttttcactc atattctgct
    45361 caaaattcaa taattgctct ttcttagctc cgccatgaac tctttctaga aacccactat
    45421 tctccagctc ttgtaaatca cgtcttatcg ttgattcaga agcattcaaa aggtttacaa
    45481 gatcttgtga tttcacgatt ttctgctgtt caagcaagtc taggattttt tgtctgcgtt
    45541 cctctgtaag cattttcacg atcacctcaa tacaaataat agcatatttt ttttctacta
    45601 gcaatataaa tcagtcaaaa acgttcataa aaattataaa tcagtcaaaa aaaaataaaa
    45661 aaccagtcag aaagactggt tttttatttt tttgtctatc atcaagccgt tttatcgttt
    45721 tttattttcg cttcttgttt ttttcatata aacagaagca ggttttcttt ccttatgaag
    45781 aagataataa taaagtccca tcccgccaaa catgaccaaa aaaccgatga ctgatcgaat
    45841 aggaaaatta ggaacaaaaa agagacagac ggataataat gatgccggaa ccattattcg
    45901 ataatagagt tgtttatcca ttttcttcac ctcatatttt ttgtaaagta atcaattgtt
    45961 ctaattctcg gtaatctaaa aattgcacac gcagatgctg ctcacctttc ttgacatcga
    46021 attggatact tcgccgcttt ttctttattc gtttgaaggt aacatcagag agtctatgtt
    46081 tgatttcctt taacggtaat tctgacaggg attctgaagg aacatagatt cttaaggata
    46141 aaagatactc ttgatatttt tcatctgtta cctctacttc tagatattcc ctaatataat
    46201 aacaataagc ttcgattcca ttatccaaag caacagtcgg atcgataact ttatagcaca
    46261 tcatgcgtga tcgattctcg tcaacccaag gaaaatacgc ctgagcattt agtgttccgc
    46321 gaacacgcct ttctttataa tctccttgtt ggatatcata actttttgtt acaaaaaatg
    46381 aagcattctt tttaggaaca ggttgcattt gtgcattctg atactggaca gattggatcg
    46441 tatggtcagt gtaaatgtat tcaacgaatg gcggtttcaa taaaccgaca ccattgtccc
    46501 aagcaagatg atcaaaccca agctggtccc taaaatagga ttgaaacatt tgattgtttg
    46561 gcttttgcca gttaaagggg tctcgataaa gctggataca tatgacttcg ttttctaatt
    46621 ccttcacttt ttctacttgt tggatgtcga gaaaaatcgg tttagggatg atttgatgat
    46681 aatagcgact ataatacatt tcccaacacg aagtgaaaca taaaccttgg taaaaaagat
    46741 cgtatcctgg aaattggttg caatcgacta ctacttcccc gttttgttgt ttcattttag
    46801 gtaaatgttc gatttcatcc tttttctcaa acaatagccg ttgagagatc tgttttgtat
    46861 tgtgatagat aaactcgcta taagctcgca tataggcgaa caccccatga gcaatcattt
    46921 ttttctgaat gaagtctcga atcaaaaatt gcttttcttt gaaaacagag atagacaata
    46981 cattttttat caataattga ttatcttcca agcgaaaact acattcgttc tcgtcatttc
    47041 ctacaactaa ccaactttcg tctcttaccg atgctagcat tattttttct tgaagctttc
    47101 gaagatcata cggatccgct tgttgtgtga aagagcggat aaatgttggc tggatcaaca
    47161 gacgtgtcaa aatagcccaa tcgcttattt cctgtttttt ttcttcttca tttaagtctg
    47221 tgagctggat agtcatcaat aatttatctt cgccaatcat tttctcacct ctttcaaatc
    47281 tttttataat ttaattataa ccaatgataa agaaaaacta aaactttatg tcttagaaac
    47341 caatttggac gattacatga tagactaagt aaaaagaaac aaagaggtgt ttacaatggg
    47401 gttgaaattt gaacgtacag ataatttaga taaacttttc gaatcatttg ctgtcgatcc
    47461 ggaaaaaaca gttgcaccaa aagaagagat cgatcgattt ctaaaaccac agccacaaaa
    47521 tgaaaagaaa aaagacaaga aacaaaagta agttaagctc aaaaaaagac ttaccagcca
    47581 aacttttatg aaagagtttg actggtaagt cttttttatt ctttttatga ttcaattgct
    47641 tgttcgattg ctgcccacgc ttcttctttt ccctgttttg taacggaaga aaagagaata
    47701 aacgtgtcat tgcgatcaaa atccaacgct tttttgattt cgctctcatg cttgttccat
    47761 ttaccacgag ggatcttatc tgccttagtg gcaacaacaa ttacagggat atcataatac
    47821 ttcaaaaatt gatacatctg gatatcttct tgagaaggct tatgacgcaa atctactaaa
    47881 gaaacgaccg cacgtagctg gtctctagtc gttaaatatg tctcgatcat ctttccccat
    47941 tttgctcgct cagttttgga tacttttgca tacccatatc ccggaacatc gacaaaatgt
    48001 aatgcgttct cgatcaaata aaaattcaat gtctgggtct ttcctggctt accggaagta
    48061 cgggctaaat tctttcgatc aatcaatgtg ttgataaaag aagatttccc tacatttgat
    48121 cgtcctgcca gagctatttc tggcaattgt gtatctggat attgttttgg tgccactgca
    48181 cttatgataa tttcagcttg atggactttc atggtctctc tccttaacaa ggtgatgaat
    48241 aaagcaagcg gctgtcgcaa aagccaaaat gacttttacg gcagcctctt ttcatcaacc
    48301 cgcttttttc tctgaatctt tatagattac tgttggctca ccagacaatt cagctgcttc
    48361 ttttgtgata atcacttttt cgatgttttc atttgaaggg atatcaaaca tcacatccat
    48421 catgatttct tcaatgatgg aacgaagtcc tcgagcaccg gtattgcgtt cgattgcttt
    48481 tttcgcaatg gctctcaacg cttcaggttc gaattcaagt tcggtattat ctagagaaag
    48541 aagtttttga tattgtttga ctagcgcatt tttcggctca gtcaagatcc gtaccagatc
    48601 atctgttgtc aatttctcta aagctgccat aacaggtaat cgtccgataa actcagggat
    48661 caatccgaat tttagtaaat cttcaggaat gatatgctgc atgacacttt cgtcttcaga
    48721 aagtttttgg ttttgtgtac caaatccaat cgtcttttcg cccatacgat tcttcacaat
    48781 cgtttcgatg ccatcaaatg caccacctac gatgaacaat atgttcgtcg tatcaatctg
    48841 aataaattct tgatgtggat gtttacgtcc gccctgaggt ggcacacttg caacagttcc
    48901 ttctagaatt ttcagcaagg cttgttggac accttcgccg gaaacgtcac gagtaataga
    48961 tacattttcg cttttacgcg caattttatc gatctcatca atatagatga tccctttttc
    49021 tgcaagttcc acattgtaat cagcagattg aagcaattta agcaaaatgt tttctacatc
    49081 ttcccccaca taaccagctt ctgtcaaact tgtcgcatct gcgattgcaa aaggtacatt
    49141 caatgttttt gctaatgttt gtgctaaaaa tgttttacca gaccctgtag gtccgatcaa
    49201 gcagatattg cttttttgca gttcaacatc atctgtgttt tcttgtgctt gctgattgac
    49261 acgtttatag tgattgtata cggcaacagc taacgagcgt tttgcgcgat cttgtccaat
    49321 cacgtagtta ttcaatactt caagaatttc tagtggttta gggacttcag tgaattcgcg
    49381 tacagcttct tcataaaatt cttcatcaat gatttcttta cataggtcga tacattcatt
    49441 acagatgtag acccctggac cagctacgat ctttttcact tcttcttggg ttttcccgca
    49501 aaaagaacag cgtacggtct cattgctact tggattgtca tacatggtct tcacccctta
    49561 acttgcaaaa agtatgcaag aaactatcaa agactttaca gtcttttact atcataacat
    49621 agtttagtaa aaagaaaaag tgtttaacaa aggatcaact gacctatacc tttgcatttt
    49681 ttactcttaa caaaaaataa ggaactgtga caaaatcgtg tcacagtccc ttatttcgaa
    49741 taaacaattt tctagaagta gcttcttcag aaatgattta ttacttgatt tctattcttt
    49801 cgcttctgtc gctgtacctg tgatcaattc gattgctttt ttcattgtca catcatgttc
    49861 cagcatatct tctgtcaaca cgcgtttgat ttgttcgatt ggcatgttgt atgtttctga
    49921 taattcttgg atttctgcat tgatttcttc ttctgttgct tgaagatttt cagcagctgc
    49981 aattgcttcg atcacaagat ttgttcttgt gcgcatttct gcttcacctt cgaattgttt
    50041 atgcaagtct tcttctgtag aaccagttaa ttgatagtac atttcaggag agataccttg
    50101 acgttgcatg ttgttcaaga attcgtccat tgaacgatgt acttcatcat gaaccatcac
    50161 gtgtggcaat tcaacgattt ctgcgttttc aacagccata cggatcgctg cttcatcttt
    50221 tgcatcgtcc gctgcttttt cttttgtttc tactaattct ttgcgatatt tttctttcaa
    50281 ttcgtctaat gttgatactt cgtcatcaac atcttttgcg aattcgtcat ctaattcagg
    50341 cacttctttt gcttttactt catggattgt cactttgaag actgcttctt ttccagcaag
    50401 atcttctgct tgataatctt ctgggaaagt tacatttaca tctagacttt cacctgattt
    50461 atgaccaact aattgatctt caaaacctgg aatgaatgag cctgaaccta attcaagtga
    50521 gtaattttcg ccttttccgc catcaaacgc ttcgccatct acaaagcctt cgaagtcgat
    50581 tactactgta tcgccatttt cagctgcagc atcttctttg ataactaatt cagcttgtgc
    50641 ttcttgttca cgtttgatac gtgcatccac gtcagcatct gttacttcac ggtcttgttt
    50701 ttcaacaact agatctttat attgtcctaa ttttacttct ggtttcactg ttacttcagc
    50761 agtgattacc cagtcttgac ctttttccat gctttcaaca tcgatttttg gttgagaaac
    50821 aggatcgatg ccagcttctt tgacagcagc ttcataagct tctggtaata cagcattcaa
    50881 tgcatcttca tataaagctt cttcaccgta catacggttg aatacttgac gagaaacttt
    50941 ccctttacgg aatccaggta cgttcaagct ttttttcact ttattaaacg cagttgttaa
    51001 tcctttttgg atttcgtctt gcgcaatcgt aaattttaaa acaccatcat tcgtgccttt
    51061 tttttcaaat gttgcagtca tttaattccc tccgagttta gaaattcatt ttatacatca
    51121 aaaacgtttc atgcatacct ttaaatagta cactaaccct ttcaaattgt aaacatattg
    51181 aatggataga atccttgttt ttcataacat ttttatcttt ttcactgata aaatctaatg
    51241 gaagaagatc atttgctgca aaattttttc tctttttttt aaaaaatctt gtttttcatc
    51301 ttctgtacct tcatacatcg tttttcctgt acacgcctct acagtcagtt gaaaccagcg
    51361 cttcgggtct tcgatgtatg tatcatagac aggataaaca attgcagatt gcaacgtgaa
    51421 ttcttctttt aacacggaac taagcagcgc atcttcattc ccgtaacgat ctgaaaatac
    51481 acataattgc tggtaacttg cctgctgctg cggctttggc agatcttttg gtatgacttt
    51541 gactaacttt tcttcaatcg tcaaatagaa aacttgatgg cattcgttca attgcctaag
    51601 tgtctccagt aattttgccc ttgctaaaat atggacctct ggcgatacaa taagtttact
    51661 cgctgtttgg ataaactcat gataaggaag ctgttcgatc tcatcaatag acgcaagctg
    51721 acgtgcaggt tccaacgaag gaagttcctc cgatttattg tggagtgcct tgatcttctg
    51781 cctctccatt tgtccggata attcttctgc aaattggatt ttttcaatga cccgctgctc
    51841 gaaagcttca taaaaatctg tacttgctat caattttcta gcatataaaa aatcttgtgt
    51901 actgattaac aagtcaaaat aaaattcagc aaactcctca ttttgaagat actgtttttc
    51961 atgcaagagt gcttgcttca atgcttcttt tttctcgtcc aactcgtaaa gacaaaaaac
    52021 aagcaggcta ttagcctcaa agctttcttt caactcgtaa gctcgttgaa ataattcttt
    52081 tgcctgctga tattgctggt ttgctagtgc ttgttgtgcc actcgcatta aattctcata
    52141 tttttctgga aaatcaatcg gcttcacgca gtgtcctcct cttgctcata ttcagctcat
    52201 gttcaatagt agcaaaacaa aaaaagcatg acaattaaaa ataactgaag caccctctaa
    52261 aagctagatt ttagatctga cttttagaag gtgctttcaa ctgttactgc tttttattgc
    52321 tcatcagctg ttgacttcct ggttgaacgc tttgatcaga ttgatcgtaa caacacttgt
    52381 attagtgaaa aaatcgccca gatgttgctt tttctgatta aagactgctg gaagataccc
    52441 taacatcagc aaaggaaatt ttagaatgaa ccggcaagca ccttctctaa ctaaaacggt
    52501 tgaccagcta agttcttctt catcaaagct gatgactcga ataccaaaga tcattttccc
    52561 aatcgtttgg ccatgattga atttcgtcaa taaaataaaa tacgctagat aaataagtaa
    52621 ggctgtgaat ccgtagagac tcagataaga atctgaaaaa ttaagccaac ctagattttt
    52681 ggcaatacca agtgttaaac gcgtaatagc tccgatacac aaaagatcga ccaagaaggc
    52741 aaacattcgg ataaaaaaac ctgcatagaa atacttagga aaatcatttg cttttggcgg
    52801 ttcatttctt gtgtccgtat actttttcca tttacgttgt ttctttttga tttcttcggg
    52861 cgtcaaaggc tctctttcaa aagagctcag taccttttgg gaaaagttgg agtcaggtcc
    52921 tacagcaggc tgctgttgct tatctttttc ttgttcctta ttttcatttg aaagctctga
    52981 catgcttact cacctccgta ataatacatt gcttttggtg attccgctgt ccctagattc
    53041 tcaagaacgg ataagatctg actagtctca gaaggcttca atccctggaa ttctgctagt
    53101 ttacttccta accatgtact agcaaaccca gatggcgtgg aagaatattc tactagttcc
    53161 gcatcttcaa gctgttgttc ctttcgtata gcttttaaag catcttcagg aaatcccaat
    53221 tcatcgacta aacctacttc ttttgcttgg acaccatcat aaatccttcc atcagcaatt
    53281 tttttgactt cttcttcaga tttattccgt ccctcgctga cgattgctac aaaacgacta
    53341 tatgcgctgt cgatatatgc ttgaagcacc gcttcttctt cttttgtctc tggtcgcgtt
    53401 cctgaaccca tatctttcaa cgctccgctt ttaactgttg tatcttccac acccagtttt
    53461 tctagaagtc ctgaataatt caatcctgac atgatcacac caattgagcc ggtcactgtt
    53521 tcttctgttg caaagatttt atctgcttga gcagaaatat agtagccacc gctagctgcc
    53581 atgtttttca tgctgacata cattgggata tcatgttctt tacgaatcgt atccaatttc
    53641 ttagcgattt ccgcactttc gtagacaccg ccaccaggag aatttacttc taaaaagata
    53701 cctttgactg ttggatcttc ttcaatcgcc ttcagttgtt ccataaaatt tttatgattg
    53761 taaccttcag aagcaaataa acctgaagac cctcccgcag caatcgttcc atctactgat
    53821 aattttacga ttttttgcgt actgtctccc tcttccaaca catttggagc tagttcttca
    53881 tccccatata accaactgtt caatccctca atttgatcgt tttcctgagg cttagtcaaa
    53941 ctagctgaaa ctaacgaaac cacaaataat cctgcagcaa tcagaactgc tgcccaacgt
    54001 cttttattca ttctttctcc tttctaatac aagtttttta tgacgatcac agtttctgac
    54061 tgctcagaag tgtcgaaccg ctctgctttt tcttcccgcg catacccgga aaacgactct
    54121 tttgttaatt catcttctac cgtaaactca cgagcttgag caacttccaa ggcatcaggt
    54181 gcgatttctt ggatgctatc ccagccagta tctaaaaata ttttcgtatc atctgataca
    54241 ccagctgatg cttcgaattt ggacaattgt ttttttaaca ttcccagtgt catgatctca
    54301 atttttgaat ccatttttac tcctcctcta tccgattact ttctattgta ccgaactcct
    54361 gaaaaagatg atagataaaa acccattatt ttttgacata aaaaggacat ttgacaaaga
    54421 atttgatata taccaattta ttttttattc tttttttgtt gacaagaaca ttcgcaaaag
    54481 gttatgattt taaatgtttc cagataaaaa acaaaaagga ggatagttat accttttagg
    54541 atagcgccag gtctgtgtaa acagatgacg aggagagggt ttatcgaaag attcggcgga
    54601 tggccctagg gactgcactc tacagaaaat ccacaaaaaa tgtctgcaaa gataaaacaa
    54661 aaggattttc ctgcagctgg aagcattcat acgaattcat tatagaaagt aggatgtttt
    54721 ttatgtgcgg aattgttgga atgattggat taaaaaatgt aacaccagga ttgattgacg
    54781 gtctagaaaa attagaatac cgtggttatg attcagctgg tatctttgtc tcagatggca
    54841 caactgatta tctggtcaaa gcacaaggca gaattcaaaa tttgaaaaac aaaataaata
    54901 ttgatactac aggaaatata ggtattggtc atacacgatg ggcaactcac gggcaacctt
    54961 ctgaagaaaa cgcccatcca catacttccc aaagtggacg cttcgtgctc gttcacaacg
    55021 gcgtaatcga aaactttgaa gaacttaaaa ttgcttattt agcaaatgac cactttattg
    55081 gtgagaccga tactgagatt atcgctcatc taattgaaac tttcgcgaag gatactacaa
    55141 cgcaagaggc gtttttaaaa gctttgcggg tcatcaaagg ttcttacgct ttcgctttga
    55201 ttgatcggac agcacctgat gttatttacg tcgctaaaaa taaaagtcca ctattaatcg
    55261 gactcggcga tggattcaat gtgattgcca gcgatgcaat ggctatgctt gctcatacga
    55321 aggaattcgt tgagattgaa gatgaagaga tggttaccgt cacatcagaa aaagttatta
    55381 ttcaaaattt tgcaggtgac atcgtagaac gttcttcatt cgaagcacaa gtagatgctt
    55441 cagatatcga gaaaggtacc tatccttttt atatgctgaa agaaatcgac gaacagccta
    55501 ttatcatgcg tcgtatcgct caaaaatacg taacagaaga caatcgtgtc tctcttgatc
    55561 aaaagctggt cgatacattg tctgatagcg atcgaatcta tatcgttgct tgcggaacta
    55621 gttaccatgc ggggttagca ggtaaacaga ctttggaaaa attgacacag attcctgttg
    55681 aggttcattt agccagtgaa tttggctata acacacctct tctttcaaaa aaaccattct
    55741 ttattttctt gagtcaaagt ggcgaaacag cagacagccg ccaagtgctg gtaaaaatca
    55801 accgtctcgg ctacccttca cttacgatta caaatgttgc tggttctact ctttcgcggg
    55861 aagcatcctt tacactgcta ttgcatgctg gacccgaaat cgcagtagca tcaacgaaag
    55921 cttatactgc acaaatagct gtactaactt tattagccaa agctatcggt gataaaaaag
    55981 aatttgaaac ttctcttgta ttcgatatca ctcatgaatt gagtttagtt gctaatgcga
    56041 tggaatcggt catcgcccaa aaagattatt tagaagagtt ggcagaagta tatctcagcg
    56101 atacaagaaa tgccttttac attggacgtg gtgctgacta caacgtttct cttgaagctg
    56161 ctttgaaatt gaaagaaatc agttatatcc aggcagaagg ttttgccgct ggcgaattga
    56221 aacatggaac gattgctttg atcgaagaag gaacaccagt gatcggaatc atcagtgaag
    56281 aagtgactgg tgcgcatact cgaggaaacc tgaaagaagt cgaaagccgt ggcgctaaaa
    56341 cactagttat tgtctcagag ggattagaaa aggaaagtga ccagctggtg ctaccaactg
    56401 tccaccctta tctaactact ctaaccacag tcgtaccgac tcaattactt gcatattacg
    56461 caacgctatt acggggattc gacgttgaca aaccacgtaa tttagcgaaa tcagtgacag
    56521 tagaataata aaagaacaag gaccagtgtc agacatctga cactggtcct tgttctttta
    56581 ttttttatga aaatatctct taatccagtc cgatttcttc tttgactact gccgcgattt
    56641 tatcgacata gtaattaact ttctcatcag taggcgcttc tgccatcact cgaagtaatg
    56701 gttctgtacc ggaaggacga actaggattc ttccttctga tcccatttca gcttctgcct
    56761 cttcaatcac ttttttgatt gccggaacat ccatcgcacc gtttttatca cttacgcgga
    56821 tattcactaa tttttgcgga tagattgtta cctctgctgc aagctctgat aatttcttac
    56881 ctgtctgttt catgatattc agtaactgaa ttcctgaaag catcccatct ccagttgtgt
    56941 taaaatctaa gaaaatcatg tgcccagact gctcgccgcc aaagttataa tcgtttttgc
    57001 gcatttcttc tacaacgtaa cgatcaccaa cttgtgtaac gacatctttc aaaccgattc
    57061 cttccaccgc tttgtggaat cctaagttac tcatgacagt cgtaacgatc gtatcttttt
    57121 tcaatcgatt tttttctgcc aagtatttag cacagataaa catgatttta tcaccgtcga
    57181 caatgtttcc aagttcatcc accgcaataa tacgatcgcc atcgccatcg aaagctagtc
    57241 cagcatctgc tcctttttca acgaccatct cagctaaacg ttctggatgg gtagagccta
    57301 cgccgtcatt gatatttaac ccgtctggat ttgtgcccat tgtataaaaa tctgtttcaa
    57361 gatcggcaaa caaacgatta acacttgttg aagttgctcc gtttgctgca tcgacacaaa
    57421 tggtcaaacc ggaaaggtca ccgttgatcg tttgtacaag gaattgagaa tatttcaata
    57481 agccttctgg aaattcttct acagttccca atccttcagc tgatggacga ggcaattcat
    57541 ccacttcagc atctaataat gcttcaattt ctagctcttg gtcatctact agtttaaaac
    57601 catctgcacc gaaaaatttg attccattat cttgtgctgg attatgagaa gcagaaatca
    57661 tgacccctgc gcttgctttt tgcaaacgtg tcagataagc aacacctggt gtagagatca
    57721 cacctagctg gaacacttcg atacccaccg ataaaagtcc tgaaatcagc gcttcttcta
    57781 acatttgacc tgagattctt gtatcccgcc ctactaacac gcgtgggcgt tttccttctt
    57841 cttcatgctg gcttaggaca taacctccgc accgtcccag cttaaatgca agttctggcg
    57901 taagttcctt gttggcttca ccgcgtacgc cgtctgttcc aaaatattta cccatagttg
    57961 taaaattact cctttaactt aattttctga ggaatttgtt ctgctcattt gtgttgattc
    58021 gcttgtttct gatgtttctt ctgtacttgt ggtcgagctg cttgtcccag attccgaact
    58081 ggaagaaatg gttgttgtcg atggttccgt tcctgaatca gcagatgaaa tacttctact
    58141 cgtacttgta ttttcttgtg tccgactgct cgtcgaagca gagctactgc ttgacgtttg
    58201 caacacgggt gtaatctcca cactaactga ttcgggcttg atacttaacc cctcttctac
    58261 tggtatttca attttacgag ttgttcgatg attgatacct gagacattga tcggtacagc
    58321 aatactgtca ccgatcgatg caagcaaatc gctagagccg cttacttctg cttccagttt
    58381 tgaaaaactg aaatcatagc tttctacccc ggcagctggt gttccttgct gtatcccata
    58441 aagtcgtacc gacttgcttg gcttgatcga atcagctctc actgttactt gcactggatc
    58501 agagacgata cttaatactt cccctgctgc attcagcgcc tgtattggga cctcactatt
    58561 aatcccatca tctgtgacca tcgaagcgtc cacatcagct actactcgtt tgatttctgc
    58621 caatgttttg tcacctgtag tgatagagac ttttttagga ctaacggaag tatcatcaag
    58681 ttcatatcca gatggtgtga acgttgaagg aatcaacgtt tccacatcga aatcttttat
    58741 tacctttttc tcaaccgtta ctgtaatagt cgatggttcg atctttgctg tgacagcact
    58801 gctcaaattt tgaattttta gcggaacttc atgtgttcct tcgcccagct tagtgatatc
    58861 tgctgtgacg cggaacatcc gtgtatcttc gtttgcctct gcattcaact gaactcggtt
    58921 tgcactggaa agtttgacag tcactgcatt ttcatatcca tggatatagt agcgctttga
    58981 atcataagaa atcttgatcg gcacccccgt aactgtttga ttatacgctt catttccaga
    59041 aagcgtattt ggaacggact ggccatttgc attgaagtac agcgcaatac tgaacagcaa
    59101 tgcaataaaa ctgtaaagaa tgcttgtccg tttctctttt gagatcattt gcgatcccct
    59161 cccttagtca taccgtctag gaaagattga atcacgtttt tcttgttttt tgttttctct
    59221 tcagcaatta gttctctacg caagattgcc aaatattctt gctgggataa gccagccatc
    59281 agttcattat ctaacgtgat gctgacgtcc ccggtttctt cagagacaac gatggtaatc
    59341 gcgtcactga cttcgcttat accgacagct gcccggtgtc gagtcccgaa ttctttaggg
    59401 atcaacatac tttctgatag aggaagatag gcgcttgcta ctgcgatctt tccttctttt
    59461 acaataactg caccgtcatg cagcggtgta ttaggaataa agatattgat cagcagctcc
    59521 ccagtgatat ctgcatctaa agcaatccct gtctcaatat actcatctaa tccagtatga
    59581 cgttcgatag tgatcaacgc accgattttt cgcttggaca tatattggat ggctttgtca
    59641 aaagacaaga tcatcttctc atcttcctgc tgttcgcttt ttgattgttt gaaaagcgaa
    59701 ctgcgtccaa gatgttccag tcctctccgg atttccggct gaaaaatcac gatagcagct
    59761 atcaccccgt acgtaatgac ttggttcatc agccaagaca aggtgtgcag accaatgatt
    59821 tccgctacga ttcggataac aataaaaata gctacacctt tcagaagctg aatcgctttt
    59881 gtgcctcgca gcagttggat cagtttgtat acaagatacc agacaaccag aatatcaagt
    59941 atgttcacca aaaaattcag agagaacaag tcaccggaaa acatttgctg ccaatagtcc
    60001 aaattaaaaa gttccccgat ttgaaatgac ataaaaagcc tctcttctct tttgagattt
    60061 cctctctagt atatcatatg ttttaatttt agaggctgat atgctcgtat ttttcttgag
    60121 aaaaacgcat aattttcaag aaaattgcaa gtatgcgttt tatttttctc tgcaataaat
    60181 atttttaaac ttcagagaat tattcattat attttttctg ttatttttcc tttttttctt
    60241 ttgtagcttg ttccattttt ttacgtcgtt ctgctctggc agctcttcta gcagctcttc
    60301 tttcttctgc ttcaaggtcc gtcgtttttt cttttctagt cttaacgggt acatcgatag
    60361 attcctctgg ttcaagtcgt ttcttgattt tttctaattc tcccgtcagt gcagcatagt
    60421 tgtaaaaacg tgttttagcg tcgtggacag tcttttcaaa taaagctttt gcaagatttg
    60481 gatttgcgtt atctagcgag gaaaagcgaa cttgtttcct catgaaatca ggcatagcag
    60541 agaaatcagg ttttttgtag tccaaagtca ttgggttctt gtttttttcg accattgtag
    60601 ggttatatcg atataatgac caataaccag aagaaacagc ttcttttgct tctttaagcg
    60661 attctttcat tccgccaagc aagccatgtg tgatacaagg cgtataggca ataatcagag
    60721 aaggaccagg atacttttct gcttcttcaa atgccttgat cgtttgcatt tgattggcac
    60781 ctgaagcaat ttgcgccaca taaacatttc catatgtcat cgccatcatt cctagatctt
    60841 tctttgaagc atactttcca ctagccgaaa atttagcgat tgccgaagct ggtgttgctt
    60901 ttgaggtttg accgccagta ttggaataga cttcgttatc caaaacaagg atattcacgt
    60961 ctgctccgct ggcaagtaca tgatcgatcc cgccaaaacc aatgtcgtaa gcccatccgt
    61021 ctccaccaat catccattgg ctgtttttta cgaatagatc ctttctcttg tatatatcct
    61081 ccagttcagg gaaaattgat cgttcgcttt cgatcgcagc ttgcagtttt gctgctcttt
    61141 gctgcgttcc ttcactctca aacatgtgta ctaaccagtc ttccatcaat tctcgtagtt
    61201 cttctgatac ttttggcaat acttctttga ttgaacttgc caaagcctcg cgacgagtct
    61261 gtgccgctag aagcatacca taaccaaatt cagcattatc ttccaataaa gaatttgacc
    61321 atgcaggccc ttgaccacat tcattggtcg tataaggaga agcaggagaa gcaccgcccc
    61381 aaatagaaga acagcctgtc gcattcgcga tcatcattcg atcaccgaac atttgtgtca
    61441 ataattttac ataaggtgtt tcgccacagc ctgagcaagc gcccgagaat tcaagaagcg
    61501 gttgattgaa ttgtgtagac aagacagtat tctttccttt gactggattt gctttttgtc
    61561 ttaatgtcat tgcaaaagcc caattcacag cttgttcttt ctgttcttca taaggcttca
    61621 tcactaaagc tttttctttt gcgggacaag cctctacaca cagaccacaa cctgtacagt
    61681 cttccactga aacttggata cggtatttta cgccgtctgc gcctcgcatt tctctcacga
    61741 taaatccttc tggcgcttct tccatttcct cttcatctgc taaaaatgga cggatggcag
    61801 catgaggaca aacaaaggca cattcattac acatcgtaca gcgatcacta atccactcag
    61861 gtacttctaa agcgacgccc cgcttttcca tagaagccgt tcctaaaggc atttcgccag
    61921 ttgtcattcc atttgctaca agtgtaccaa cagagagttg atttccttcc tgtgcattca
    61981 ctggttcaag tatttcttgt atataaccag tgttcctttt attgattttt tcaggcatct
    62041 ccaacgttct ccaatggtct gggatcgcga cttgatgaag cagttcggtc gtccgatcga
    62101 ttgcttgtat gtttttttct acgatagcca ttgatttatg tccatagctt ttcagggctt
    62161 cttcttttag cagcggaagc acctcatcaa aaggaatgat gtcagctaat ttaaaaaaag
    62221 ccgtttccat tgccgtattg atccggcgtc ccaaaccgac ttcttgggcc aatctcatgg
    62281 cattgatcgt atagaatcta atgttatttt cagccaagta acgttttaat tttaagggca
    62341 gatgcgtttc taattgttcg tcgctccaaa gagtattcaa taaaaaaatg ccacctggct
    62401 tcaatccttt gaccaagtca tagctatgca ggtaagctgg tgtgtgacag gcaacaaggt
    62461 ccgcatgctc gacaagatac gctgaacgta tcggcgtatc tccaaaacga agatgagaga
    62521 cagtcagacc gccagatttt ttcgaatcat aataaaaata gccttgcgca tatttatcgg
    62581 tgtgatctcc aataatcttg atagctgatt tatttgctcc aactgttccg tcagatccaa
    62641 atccccaaaa cttggcctgg aatgtttgcg gttctgtcaa atccagactt tcctttggtt
    62701 ccaaagattg ataagtcaca tcatccacga tccctatggt aaaccgtttt ttgcgtatgc
    62761 ttgggtcttt tttcaattca tcaaaaactg ctgagatttg gtcgggagtc acatctttag
    62821 accccaatcc gtagcgacca ccaataacag ccgggcgaag ttcagaatca tataacgcac
    62881 tttgaacgtc taataagaga ggttctccac ctgcccctgg ttctttactt cgatcaagaa
    62941 cagcaattgt ttttactgta tgaggcaact tttgcacgaa tgtttccact ggaaaaggac
    63001 gataaagatg gatattcaaa aaacctgttt tccgtccgtt tgcattcaag taatcaatcg
    63061 tttgttcaat cgtctgtgca actgatccca tagaaacaat gacttcttcc gcatcgtctg
    63121 ctccgtaata agtcaccaag tcataagaag ttcctcgtaa tcggttgatc tctttcatat
    63181 atttttgaac gatttcaggt aatttatcat aataggggtt gatcgtttcc cgttgttgaa
    63241 aatggatgtc tggattctgg ttcgtaccac taacagtcgg atgattggga ttcatccctc
    63301 gtttacgaaa tgaagctaat ttctcctgat tgatcagagg agctaattct tcatattcca
    63361 aaacttcgat tttttgaatc tcgtgactcg tacggaatcc atcaaagaaa ttcaaaaaag
    63421 ggacttctcc ttcaatagaa gcaagatggg caacaggtgc taaatccatc acttcttgta
    63481 cactgctttc agctaacata gcaaatcctg tttgtcttgc agccatcacg tctccgtgat
    63541 ctccgaaaat attcaacgca tttgtcgtca ctgcccgact agcaacgtgg aaaacacttg
    63601 gcagtagttc cccagcaatc ttgtacatat tcggtatcat caaaagcagc ccttgtgaag
    63661 cggtatatgt agttgtcagt gcaccagttt tcaatgatcc atggaccaca ccagctgctc
    63721 ctgcttcgga ttgcatttct actactttta ctggttgacc gaatacgttt tcttttcctg
    63781 ctgctgacca ttgatctact aattcagcca tggtcgaact gggtgttatt ggatatattg
    63841 cagcaatctc ggtaaatgca taagaaatat atgcggctgc cgtattgcca tccattgttt
    63901 tcatttttcg catgattcat catccttgtt catattctct cttattatct gttccattat
    63961 aacgtaaaac atgccatttt tttcttttat ttataaaaat attttacatg tatctatttg
    64021 aattggtcat ctaattttta gacaaacagt ctaaatcgtt gccttttttt gtcagacatg
    64081 tataaactat aagcgaaaga ggtgttttaa catggatata tcagtgattg atgcaacgaa
    64141 aacaaataca caaaaaggaa tcctttatgg ttcatcgaat gctcctaaaa aaatggtcga
    64201 attcatcaac ttagcttgtc cgtattgccg acaatggttt gaagaatctt atgagctatt
    64261 agaagaagca gtccaaagcg ggcaattgca gcgagtgatc aaattgttcg ataaagaaaa
    64321 agaaagctta cagcgaggga acgtgatgca ccggtatctc acaatcagcg atggccaaaa
    64381 agcgatcaaa gagatcaaac aaatattcga tactcaagac gagtggaaac atctttctct
    64441 ccaagaagta gcggattttg cagtagataa actaaagctg acagaacaaa aagacgaaca
    64501 gctgagccaa gctgtcatca acgaagctga gcaagcacat attcgatttg ttccaactgt
    64561 catcttgggt aaagaaatct ttgatgaatc tatttcaata gaggaattaa aagaattgat
    64621 ccaaacaaaa taaaaaaata aggagcgtgg gacaaaagta aagaacactt ttgtctcacg
    64681 ctctaaacac gtataaacgg cggaagcaga agcaactcct tcttatttct tggagttaaa
    64741 cgcttctgtc ccagcctcct tattccgaat aaatggtgtc caaaagcttg catctgccag
    64801 attatctcat ttcttatgac aagctaagca aattatctcc accaaataat ttattcatat
    64861 ttttgacttg cgcatactaa ctaattctta aattttcata caaaatttct caatttccct
    64921 taacgagtaa tatttatgta cggtgattct cactagtatc ccaatcactt tttaagttat
    64981 cccgatttca attctacttc aaaaatagtt gcttttatgt atgctgttag ttgattagat
    65041 ggtcatttgt tgagctaggt cgtttatttt aaacaagttg tttctttagc ttatacctat
    65101 ctcgtctacc aaacgcaaga tggcaaacac aaatgcatac gcatctgtat ttgccacttt
    65161 gattcgtata aagctaacaa ctattaactc ctctcagcta atagttgctc tcttttttat
    65221 tcagattcat ttttgctgat cacagcctag tatttcaatg gttttgaaca ctaaaccaaa
    65281 ttgttccatt acaacattca ctggctgatg aaatggatta gtagatttcg attattcaaa
    65341 gcgattttct attggtggat cgtgttccca actaataaga cggattccaa acctatcgta
    65401 cagatcttct aaaccactta taaattttgc acctatttca ggtgttttat tgcgtggata
    65461 ttctattgtt acgccattaa atggatacca attaggatta ggctctcttt ttttctgtac
    65521 atctcccata gaatagttag cactttctgg gacataatat attcttcgac catcctctaa
    65581 ttcatctaat aagatatttc gtgatcgtct atcacttgct aaatgtagac gccacgtgcg
    65641 ataccatgcc atgctacctg catctgcaga aaatccatca aataatgcaa caattgtatc
    65701 ttctatcaca atcctttccc catctacttc atattctaat ctaaaatcaa actcccctcg
    65761 ggtaatttct ggtcttggtg gcttaggacc caatattatt ctacttaaaa ccgcattcgt
    65821 tcccagatga aacacagcta taacaacaat aatgattaat attttgtttc tatttgataa
    65881 atttctcatt attcgcacat cacctctaca ttctcacata ttagttcgta atactccttt
    65941 aatatcaaaa tatctactgg tcgtaataat attcgctatg aattcctact actcgtataa
    66001 gaaaggccaa atcatcagct tttacttgct gatgatttgg cttgtttcta tttatcgtaa
    66061 ttgttttcta atcaccaaaa ttgttaacaa tcggttcaga tatttcccag ttgattaagg
    66121 taattccgta ttgtgtcaaa acttcttgcg cttctccgaa attaagtaca gttcttatgt
    66181 atccactttc tcctaatata aagtctacct ctcttttaaa accttcctcg agatttctaa
    66241 gggctatatg tggttttaat gacattgatt gtacattttc ccccatataa tattgcgcac
    66301 ttcctcgact aaaatagatt cctagatcgt ccccaaaagg tagatcttct ctaccactag
    66361 ctaatctact tctccatctt cgttctcttt tcatagaacc tgcgctgaac tcacacccgt
    66421 taaactcagc tatgacagta tcttcaatta tgttaatctg tccatctagt tcgtattcaa
    66481 tcctaaatgg aaattctcca taggtgattt ccggttcggg tattttaggt gagattaatg
    66541 caaagaaagg aaatattaag cttggcaaca tcaaaaaaac tcctcctatg atcacaattc
    66601 ccgatgtaat ccaaaatata atttgtacaa ttctcattga tccattgtat tccattttat
    66661 tccccctatt actattcata tccgcctatc tatatcgatc ttccaatgca gagataattg
    66721 cttccatacc ttgatttttt actgagttac ctatgcgaga tatcattctc cactaaggtg
    66781 catcatattg tctatctaac atgattaatt ctccaatagg tgtatactcc tccaaaaaca
    66841 acatttaatg catctccctc gacaacataa gctaccatgt ttgctgtata tgtgtttgag
    66901 tctaattcat aagcagataa atttactgtc gctggattaa atataatcgc attcgtattt
    66961 atagctactg aatttgctgc ttcagcacca ccttttgaat gtccgatcat tgtgatttca
    67021 atagtaggat ttacgtggac agccctcacc gtttaccctg accattatag aaatcgctta
    67081 cttttttgaa ctacgcaaca aaggatacaa tgctcctaac ttcactgtct ccatttttgt
    67141 ccactaagga atataaaaaa taggcattaa ttcatttaat tcggtcacaa cacgttacct
    67201 tttaaatcat tatactgtat ctcatacatt attatcaata aactattata aaaatgcaaa
    67261 aaatgcttta tcaatctatt ttgtaattgg tcataatatc attgaaatca taccctgtat
    67321 cgatttttcc tatgaatctc gtctatttgt gattgacgaa aaagaggcaa gacagacact
    67381 ggaatggtaa ttttacccac tattttgctc caactatttg taatcgtacc cacttttgaa
    67441 ataccgagat gatcatttta attgatatgc tgattcccaa gcaaaacccc aagaaattaa
    67501 atgctctatc gcatctagct tcttgggttt tgcttatata aattccaaca tttaaatttt
    67561 ttatgctgtt cggtctcaga aatgccgttt ttgcttatat cacaatatca agatgtcaaa
    67621 ttattcgtgt tgccgatgac tttgattaat ttttttcaaa ttgtttatta agactaatgc
    67681 tgtctttttg cagataccaa tgttcgaact ttttaacatt atcatatgat cctgcaagtt
    67741 ttaacttctt accattagat gttatcaaag ttataattaa ccttgccttt ttcccattag
    67801 gatcttttat tttatgaatt ttctgcaggt aatctctcct aatggcagct atttttacct
    67861 catcagtgct gataaaccat tgatcatcca catacatact gcctgttatg ttgtgttttt
    67921 ccatttcttc cgagaacgaa aagtttaagg ctcgttctta cttccaaagt tgaatgagtc
    67981 catggattgg acttagtgtg agaattgaga acaacaataa gaatccatat cctcccgcaa
    68041 acatccctaa ggctatactg tctctccatc cataagtagg attagaagag aaaagagtca
    68101 ccgtttgtaa taatatgaaa aggaataatc cagcacaaac accaaagata acaactccaa
    68161 acattgaatt tttatacaat gaccatttat ttataggctt ttctttcatt ttacttcccc
    68221 ctactgttct gttcacacgg aatgaattca aagttcataa gccctcctct ttgaacatat
    68281 gaatacgact tgctaactat actttaaaaa agcttgtttt aagcggttat aggcgagttg
    68341 taatctctat tcatctcatt agcaaataac ttgccgaaaa gtctactgaa attaaagcag
    68401 atagtggaag aattatttag ccaggataga cactatttgt gaaacacatg tctttacttt
    68461 tgaaattcta tgatgaaaag ccttggaata cagtagctct taattggtaa tactttttcc
    68521 attataaata acctcttttc attttatatt tatcccctct aaaaataata tctaatctaa
    68581 tattttaaac ttatatttcc ctcgctgtgc taatagagca ttactaaata aatagaaact
    68641 agaaaaaagc attacgcctg ccagaataaa ccaattattt gt
//
LOCUS       DAPBAF010000009        67948 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.009, whole genome shotgun sequence.
ACCESSION   DAPBAF010000009 DAPBAF010000000
VERSION     DAPBAF010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 67948)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 67948)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..67948
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.009"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            <1..109
                     /locus_tag="RD451_000692"
     CDS             <1..109
                     /locus_tag="RD451_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002606082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDT7565980.1"
                     /translation="YIPIKDIILHFEKYDYRFHWNSDNSVIEIWIPIQD"
     gene            237..1451
                     /locus_tag="RD451_000693"
     CDS             237..1451
                     /locus_tag="RD451_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HDT7565981.1"
                     /translation="MNDKNFIEELRQKREEYGVTQTRLAVACGISREYYNRIEKGKQP
                     LNDELREIIEKQIERFNPQEPLFLLIDYFRVRFPTTDALAIIRDVLQLKSNYMLYEDY
                     GKYGYESKYVLGDINIMCSMQEHLGVLLELKGKGCRQMECYLLAQERSWYDFMLDCMT
                     AGGVMKRLDLAINDKAGILDIPKLKEKYKAGECMSYFRMQKDYSGTEKCGSDLPKNTG
                     ETLYLGSTSSELYMCAYQKNYEQYVKNGTEIEDTEIKNRFEIRMKNERAYYAVVDLLT
                     YRDAERTAFSIINHYVRFVDREDDKPKSQWITNDDWAWFVGENREPIRLTTKPEPYTL
                     QKALHWLQRQVAPTIKMVQALDRENRTTILKDMIEQAELKDKHKHLLQLEKSTIEERI
                     DTAVPQENDGIF"
     gene            2440..2649
                     /locus_tag="RD451_000694"
     CDS             2440..2649
                     /locus_tag="RD451_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008394616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA wybutosine-synthesizing protein 3-like
                     protein"
                     /protein_id="HDT7565982.1"
                     /translation="MNCLERFYRKGVCVIDNAVKTIQKKNGKCGIGNRGKTKIVVKEH
                     FSEKGKTMEELLTDVMLEKAKQTIA"
     gene            2761..4374
                     /locus_tag="RD451_000695"
     CDS             2761..4374
                     /locus_tag="RD451_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003019515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDT7565983.1"
                     /translation="MKQQIYNTALYLRLSRDDELQGESSSITTQRSMLRLYAKEHHLN
                     VIDEYIDDGWSGTNFDRPSFQRMIEDIEAGKINCVVTKDLSRLGRNYIMTGQYTELYF
                     PSHNVRYIAIDDGVDSEKGESEIAPFKNIINEWVARDTSRKVKSAFKTKFAEGAHYGA
                     YAPLGYKKHPDIKGKLLVDDETKWIIEKIFSLAYQGYGSAKITKQLRAEKVPTASWLN
                     FTRYGTFAHIFEGKPESKRYEWTIAHVKAILKSEVYIGNSVHNMQSTVSFKSKKKVRK
                     PESEWFRVENTHEPIIDKEVFYRVQEQIKSRRRQTKEKATPIFAGLVKCADCGWSMRF
                     GTNKTNKTPYSYYACSYYGQFGKGNCSMHYIRYDVLYQAVLERLQYWAKAVQQDEEKV
                     LNKIQKAGNAERIREKKKKASTLKKAENRQNEIDRLFAKMYEDRACEKITERNFVMLS
                     SKYQKEQIELEQQITSLREELSKMEQDMIGAEKWIELIKEYSVPKELTAPLLNAMIEK
                     ILIHEATTNEDNERIQEIEIYYRFIGRVE"
     gene            4409..5620
                     /locus_tag="RD451_000696"
                     /pseudo
     CDS             4409..5620
                     /locus_tag="RD451_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
     gene            5643..6569
                     /gene="glsA"
                     /locus_tag="RD451_000697"
     CDS             5643..6569
                     /gene="glsA"
                     /locus_tag="RD451_000697"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HDT7565984.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            6777..8237
                     /locus_tag="RD451_000698"
     CDS             6777..8237
                     /locus_tag="RD451_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565985.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIREIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            8458..10221
                     /locus_tag="RD451_000699"
     CDS             8458..10221
                     /locus_tag="RD451_000699"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HDT7565986.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            10305..10763
                     /locus_tag="RD451_000700"
     CDS             10305..10763
                     /locus_tag="RD451_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HDT7565987.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            10872..11555
                     /locus_tag="RD451_000701"
     CDS             10872..11555
                     /locus_tag="RD451_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HDT7565988.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            11702..12316
                     /locus_tag="RD451_000702"
     CDS             11702..12316
                     /locus_tag="RD451_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HDT7565989.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            12332..12538
                     /locus_tag="RD451_000703"
     CDS             12332..12538
                     /locus_tag="RD451_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7565990.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     gene            13079..14209
                     /locus_tag="RD451_000704"
     CDS             13079..14209
                     /locus_tag="RD451_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HDT7565991.1"
                     /translation="MGPYLTLSMIGLLEVYSASSYRLLQADENTKSLLLRQLIFIFLS
                     WSVIFLARSVKLHYLLHPKIAGYGLALSIFFLVLVRIGIFGVTVNGAQRWISLFGIQF
                     QPSELANLFLIFYLSWFFRDGNSSPKDLKKPFLITVGITFLILFQPKIAGALMILSIA
                     WVIFWAAAVPFKKGIYLIVTFSALLIGAAGGVLYLGNKGWLPQMFNHAYERIATLRDS
                     FIDSHGAGYQMTHSFYALYNGGIFGRGLGNSITKKGYLPETETDFIFSIITEELGLIG
                     ALCVLFLLFSLCMRIFCLSSRCKNQQAGLFLLGFGTLLFVQTIMNVGSIAGLMPMTGV
                     PLPFVSYGGTSYLILSLGIGITLNISSKIQAEELALYRPEKQ"
     gene            14301..15056
                     /locus_tag="RD451_000705"
     CDS             14301..15056
                     /locus_tag="RD451_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HDT7565992.1"
                     /translation="MKVSQKIILSILLLLTLVVGYFSIEFIHGFSSAKQSSTVKKVEP
                     KSIPTTLNVALIGSDARSKDENGRSDSLLVAQYNQKTQQAKLISIMRDSYVDIPGYGM
                     NKINAAYSYGGVDLLNQTLKENFKFEAPYYASITFQDFIDCVNELFPGGVKIDAEKSL
                     DLDGVYINKGEQVMDGNTLLQYARFREDKEGDFGRIRRQQQVIKAISQQLKDVTSIFK
                     LPKAVGKLLGSIQTNLPESVLLDCGMDFLKDIC"
     gene            15114..17153
                     /locus_tag="RD451_000706"
     CDS             15114..17153
                     /locus_tag="RD451_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HDT7565993.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKTAFDSLGGKAGSTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKMITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSYQATRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLITPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(17262..18413)
                     /locus_tag="RD451_000707"
     CDS             complement(17262..18413)
                     /locus_tag="RD451_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HDT7565994.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(18567..19097)
                     /locus_tag="RD451_000708"
     CDS             complement(18567..19097)
                     /locus_tag="RD451_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HDT7565995.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(19196..19546)
                     /locus_tag="RD451_000709"
     CDS             complement(19196..19546)
                     /locus_tag="RD451_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HDT7565996.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            complement(19703..21232)
                     /gene="ahpF"
                     /locus_tag="RD451_000710"
     CDS             complement(19703..21232)
                     /gene="ahpF"
                     /locus_tag="RD451_000710"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HDT7565997.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     GTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(21242..21805)
                     /gene="ahpC"
                     /locus_tag="RD451_000711"
     CDS             complement(21242..21805)
                     /gene="ahpC"
                     /locus_tag="RD451_000711"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HDT7565998.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(21949..22611)
                     /locus_tag="RD451_000712"
     CDS             complement(21949..22611)
                     /locus_tag="RD451_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDT7565999.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            22795..24441
                     /locus_tag="RD451_000713"
     CDS             22795..24441
                     /locus_tag="RD451_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HDT7566000.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAVLLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPNMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDLQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            24432..25514
                     /gene="uxuA"
                     /locus_tag="RD451_000714"
     CDS             24432..25514
                     /gene="uxuA"
                     /locus_tag="RD451_000714"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HDT7566001.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFGLPGWEP
                     ERLAPIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLA
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNGYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(25622..27175)
                     /locus_tag="RD451_000715"
                     /pseudo
     CDS             complement(25622..27175)
                     /locus_tag="RD451_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            27323..28464
                     /locus_tag="RD451_000716"
                     /pseudo
     CDS             27323..28464
                     /locus_tag="RD451_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(28590..29669)
                     /locus_tag="RD451_000717"
     CDS             complement(28590..29669)
                     /locus_tag="RD451_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDT7566002.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVINFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVVALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(29772..30212)
                     /locus_tag="RD451_000718"
     CDS             complement(29772..30212)
                     /locus_tag="RD451_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDT7566003.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTPLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTAQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(30269..30679)
                     /locus_tag="RD451_000719"
     CDS             complement(30269..30679)
                     /locus_tag="RD451_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HDT7566004.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(30859..31293)
                     /locus_tag="RD451_000720"
     CDS             complement(30859..31293)
                     /locus_tag="RD451_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDT7566005.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVIFEERKQLFEKYM"
     gene            complement(31393..32241)
                     /locus_tag="RD451_000721"
     CDS             complement(31393..32241)
                     /locus_tag="RD451_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDT7566006.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAALGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLVFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFIFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            32630..34396
                     /locus_tag="RD451_000722"
     CDS             32630..34396
                     /locus_tag="RD451_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HDT7566007.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETSRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVMDHLDYLTDLGINGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVNDREDKLYFTRKLEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            34498..35757
                     /locus_tag="RD451_000723"
     CDS             34498..35757
                     /locus_tag="RD451_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HDT7566008.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            35904..37205
                     /locus_tag="RD451_000724"
     CDS             35904..37205
                     /locus_tag="RD451_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDT7566009.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            37208..38059
                     /locus_tag="RD451_000725"
     CDS             37208..38059
                     /locus_tag="RD451_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDT7566010.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            38072..38887
                     /locus_tag="RD451_000726"
     CDS             38072..38887
                     /locus_tag="RD451_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HDT7566011.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            39038..40204
                     /locus_tag="RD451_000727"
     CDS             39038..40204
                     /locus_tag="RD451_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDT7566012.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            40434..41081
                     /locus_tag="RD451_000728"
     CDS             40434..41081
                     /locus_tag="RD451_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HDT7566013.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            41165..42109
                     /locus_tag="RD451_000729"
     CDS             41165..42109
                     /locus_tag="RD451_000729"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HDT7566014.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            42244..43695
                     /locus_tag="RD451_000730"
     CDS             42244..43695
                     /locus_tag="RD451_000730"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HDT7566015.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            43716..44552
                     /locus_tag="RD451_000731"
     CDS             43716..44552
                     /locus_tag="RD451_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HDT7566016.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            44552..45211
                     /locus_tag="RD451_000732"
     CDS             44552..45211
                     /locus_tag="RD451_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HDT7566017.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSMHQS
                     I"
     gene            45337..46026
                     /locus_tag="RD451_000733"
     CDS             45337..46026
                     /locus_tag="RD451_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566018.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PTDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            46032..46988
                     /locus_tag="RD451_000734"
     CDS             46032..46988
                     /locus_tag="RD451_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HDT7566019.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHRIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            47032..47544
                     /locus_tag="RD451_000735"
     CDS             47032..47544
                     /locus_tag="RD451_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7566020.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSSVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(47800..48348)
                     /locus_tag="RD451_000736"
     CDS             complement(47800..48348)
                     /locus_tag="RD451_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDT7566021.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(48437..49618)
                     /locus_tag="RD451_000737"
     CDS             complement(48437..49618)
                     /locus_tag="RD451_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HDT7566022.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(49854..51362)
                     /locus_tag="RD451_000738"
     CDS             complement(49854..51362)
                     /locus_tag="RD451_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HDT7566023.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATSLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            51521..51712
                     /locus_tag="RD451_000739"
     CDS             51521..51712
                     /locus_tag="RD451_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566024.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            51915..52832
                     /locus_tag="RD451_000740"
     CDS             51915..52832
                     /locus_tag="RD451_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="viral A-type inclusion protein"
                     /protein_id="HDT7566025.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            52825..53898
                     /locus_tag="RD451_000741"
     CDS             52825..53898
                     /locus_tag="RD451_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566026.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            54046..54564
                     /locus_tag="RD451_000742"
     CDS             54046..54564
                     /locus_tag="RD451_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566027.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            54545..54937
                     /locus_tag="RD451_000743"
     CDS             54545..54937
                     /locus_tag="RD451_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HDT7566028.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVFFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            55013..55948
                     /locus_tag="RD451_000744"
     CDS             55013..55948
                     /locus_tag="RD451_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HDT7566029.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            56081..56860
                     /locus_tag="RD451_000745"
     CDS             56081..56860
                     /locus_tag="RD451_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HDT7566030.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            56853..57170
                     /locus_tag="RD451_000746"
     CDS             56853..57170
                     /locus_tag="RD451_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HDT7566031.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            57414..59024
                     /locus_tag="RD451_000747"
     CDS             57414..59024
                     /locus_tag="RD451_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HDT7566032.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            59181..60029
                     /locus_tag="RD451_000748"
     CDS             59181..60029
                     /locus_tag="RD451_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HDT7566033.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
     gene            60260..60739
                     /locus_tag="RD451_000749"
     CDS             60260..60739
                     /locus_tag="RD451_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566034.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNTDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
     gene            60772..63000
                     /locus_tag="RD451_000750"
     CDS             60772..63000
                     /locus_tag="RD451_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDT7566035.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKGRTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            63129..64772
                     /locus_tag="RD451_000751"
     CDS             63129..64772
                     /locus_tag="RD451_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HDT7566036.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKLALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(64845..65390)
                     /locus_tag="RD451_000752"
     CDS             complement(64845..65390)
                     /locus_tag="RD451_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HDT7566037.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(65413..65898)
                     /locus_tag="RD451_000753"
     CDS             complement(65413..65898)
                     /locus_tag="RD451_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDT7566038.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            complement(65888..66700)
                     /locus_tag="RD451_000754"
     CDS             complement(65888..66700)
                     /locus_tag="RD451_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HDT7566039.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            complement(66839..>67948)
                     /locus_tag="RD451_000755"
     CDS             complement(66839..>67948)
                     /locus_tag="RD451_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HDT7566040.1"
                     /translation="PILYLMEQPALSVSQSFLDKNEISYMTHTSGTTGIPKLICHSAH
                     SMGWRTKWQKTVFTKISEKKLIAFHISPVHSRFNIGISSLMSMGFPMMPLANAQSSKV
                     VHMLEAHRPIALETHPNNFVQWRFTAKEHPEAFSGIRYYHSTFDAINNQTMKTFLRTS
                     MAQDAVFLQVYGQSECGPMILKAHTLESLKTSDARDMGVGLEDMTSARITDSVGNVLP
                     ENTDGHIQLLSKGRALTYYKEDARFQENVYGDWWDSGDYGFMDKHGHLFLKDRQVDLI
                     ETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSPQPIIALAPDKEMDWNRWWEQVHELP
                     RLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQKS"
BASE COUNT        22706 a        12056 c        13355 g        19831 t
ORIGIN      
        1 gtatattcct ataaaagata ttatcctaca ctttgaaaaa tacgattatc gttttcattg
       61 gaatagtgat aattcagtta ttgaaatttg gatacctatt caagattaga agcaatttta
      121 tatccataca cacaaagcag ttagtcttag gattgactgc tttttctata cagattttta
      181 atgacaggca attatcaatt atggtagttg ccttttttga ttggaggaat tgaagaatga
      241 atgataaaaa ctttattgaa gaactaagac aaaagcgtga ggaatacgga gtaacacaaa
      301 caaggcttgc tgttgcctgt ggtatcagcc gtgaatatta caaccgcatt gaaaaaggaa
      361 aacagccatt gaatgacgaa ttaagagaaa tcatagaaaa acagattgag cgtttcaatc
      421 cgcaagaacc actattctta ttgattgatt actttcgtgt ccgctttcct actacggacg
      481 cattggcgat tatccgtgat gtattacaac tgaaatctaa ttacatgctt tatgaagatt
      541 atggaaaata cggatatgaa agcaaatatg tacttggcga catcaatatc atgtgttcca
      601 tgcaggagca tttaggtgtt ttattggaac tgaaaggcaa aggctgtcgg caaatggaat
      661 gttatctgct ggcacaggaa cgctcatggt atgacttcat gctggattgt atgacggctg
      721 gtggtgtgat gaaacggctt gatttggcta tcaatgataa agcaggaata ttggatattc
      781 caaagttaaa ggaaaaatac aaggctggcg aatgtatgtc ctacttccgt atgcagaaag
      841 attacagcgg tacagaaaaa tgcggtagcg atttaccaaa gaatacagga gaaaccttat
      901 atctcggttc aacaagtagc gaattatata tgtgtgctta tcagaaaaat tatgagcagt
      961 atgtcaagaa tggcacagaa attgaagata cggagattaa gaaccgtttt gaaatacgca
     1021 tgaagaacga acgagcctat tatgcggttg tagatttact gacctatcgg gacgctgaac
     1081 gcaccgcttt ttctatcatc aatcattatg tccgctttgt tgacagagag gacgacaagc
     1141 caaaaagtca atggataaca aatgatgatt gggcatggtt tgtaggggaa aacagagagc
     1201 cgatacgctt aaccacaaag ccagagcctt acactttaca aaaagcgttg cattggctac
     1261 aaagacaagt cgcaccaacc ataaaaatgg tacaggcatt agacagagaa aatcgtacaa
     1321 cgatactgaa agatatgatt gagcaggcag aactaaaaga caagcataaa catttattac
     1381 aattagagaa atcaaccata gaagaacgta tagataccgc tgttccacaa gagaatgacg
     1441 gtatttttta atgtaattga aaaatttcag atttagtcag caaagagctg ttttcattcc
     1501 ctatgtgaag tgaaagaaga aaaataaatt ttttattaaa tctgcaacaa aatggctact
     1561 tgcgtacaga tatggtgcga gaaaaggaaa tctaaacttt ttttgaaaat aggtcattaa
     1621 atcggggctt gctgtcccta tatgaagtga aagaagaaaa aagttttgaa aaaatgacgg
     1681 aaattcgtga ttagtggaca gtcttctgtg aaaagaggaa aaacatcatc attttgtatt
     1741 caaacaggca ttagcagttg agtgttgatg tgaaaagatg aaaatacttt gttctcaact
     1801 taacaattta aggtttccgt tccctatatg gtgcaaagaa aatatttcat tctattgttg
     1861 gcagtaacgg tatggtttgg gtagttaggg tgtgaaaagg aaaatattct tttttcatca
     1921 tcaacttagc aaaatgacat tttctatccc tatatggtgc atgaaaagaa gttaaaattt
     1981 ttccatttaa acttagcaaa tggacgtttg ctgtacagat agtagtgaaa aaggagaaaa
     2041 tcaaccgttg attgccaaaa tgaaccgttc catttgtact aataatggaa aaagttttgg
     2101 attttggtta cgtttctcct cttttccaac gcgatatata ggaaagacga tttttttctt
     2161 tcaatcgttc tttgacaact gaataaagct attcaatacg tttgacagac agctagccgt
     2221 tgaaacaaat acgccacgac ctttcccctg caagagcgag cgaaaaccta tttgtgttct
     2281 tgtaaaagat ttgtcctctt ttatcgccat gacctgtact gtcagataat gatactcccg
     2341 tacagccaca gcttgagcat taagagcgtc gcacgcaatg ggtacggcta cataagaact
     2401 atgcagaggt ggaactcctg tgggctatga caaaagccgt tgaattgctt agaaagattt
     2461 tacagaaagg gggtatgtgt tattgataat gctgtaaaaa caattcaaaa gaaaaatggc
     2521 aagtgtggca ttggcaacag aggaaagaca aagattgtag taaaagagca tttttccgaa
     2581 aagggcaaaa caatggaaga acttctaact gatgtcatgc tggaaaaagc aaagcagaca
     2641 atcgcataaa atcggtgcag ttgtaagaaa tagattgaat gacaaaaagt acccgtgtta
     2701 tactttactt gcaagcaggt attgtaaaca cgggttagtt ataaaggagg ataactgaca
     2761 atgaaacaac agatttacaa tactgcactt tatcttaggt taagccgaga tgatgaatta
     2821 cagggcgaaa gttccagcat taccacacag agaagtatgt tgcgtttata tgcaaaagaa
     2881 catcatttga atgtcattga tgaatatatt gatgacggct ggtcgggaac aaattttgac
     2941 agaccgagtt ttcaaagaat gattgaggat atagaggcag gaaaaatcaa ctgtgttgta
     3001 acgaaagacc tttcccgtct tggcagaaat tatattatga caggacaata tacagaattg
     3061 tatttcccta gtcataatgt ccgctacata gcgattgatg acggtgtaga cagcgaaaaa
     3121 ggcgaaagtg agattgcacc atttaagaac atcatcaatg aatgggtggc aagagataca
     3181 agccgtaaag tcaaatcagc atttaagaca aagtttgcgg agggggctca ttacggtgct
     3241 tatgctccgt taggatataa gaaacaccct gacatcaaag gaaaactgtt ggttgatgat
     3301 gaaacaaaat ggattattga aaaaatcttt tccctagcct atcaaggtta cggaagtgca
     3361 aaaatcacaa agcagttaag agcagaaaaa gttccgacag cgtcatggct aaattttaca
     3421 agatacggta cttttgcaca tatctttgag ggaaaacccg aaagtaagcg ttatgagtgg
     3481 acgattgctc atgtcaaggc gatattgaaa agtgaggttt atatcggaaa cagtgttcac
     3541 aatatgcagt ctacggtatc gttcaagagc aaaaagaaag tgcgtaagcc cgaaagtgaa
     3601 tggtttcgag tagaaaacac tcacgagccg attattgaca aggaagtgtt ctatcgtgtg
     3661 caggagcaga taaaatcaag acgcagacag acaaaggaaa aggcaacgcc gatttttgca
     3721 gggcttgtca agtgtgcgga ttgtggttgg tctatgagat ttggaacgaa taagacaaat
     3781 aaaacgcctt acagttatta tgcttgcagt tactacgggc agtttggcaa aggtaattgt
     3841 tctatgcact acattcgtta tgatgtgctg tatcaagccg tattggaacg cttgcagtat
     3901 tgggctaagg cagtacagca ggacgaagaa aaggtattga acaagataca gaaagctggc
     3961 aatgcagaga gaatacggga aaagaagaaa aaggcaagta cattgaagaa agccgagaac
     4021 agacaaaatg agattgaccg tttatttgcg aaaatgtatg aagatagagc ctgtgagaag
     4081 ataacagagc gaaattttgt gatgttgtcc agcaagtacc aaaaagaaca gatagaactg
     4141 gaacagcaga taacaagcct aagagaagaa ctaagtaaaa tggaacagga tatgataggt
     4201 gctgaaaagt ggattgagtt aatcaaggaa tattccgtac caaaggaact gacagcacca
     4261 ttattaaatg ccatgataga aaaaatcctc atacatgaag caacaacgaa tgaggataac
     4321 gaaagaatac aggaaattga gatatattac cgatttattg gaagagttga gtaatcaaca
     4381 agagtaatat ttttaactaa gggaaaccgg cggtgtctat acttgggtca gtcgcacatt
     4441 gggaaaacga ttcggttttg ccgcaatctt tttccaatgg tttgagataa cagttggcta
     4501 cttgaccatg ctgtatttct taactggtgc attatcctat gcaacgggta ttggtgctat
     4561 acaaaacaat aaatatctga aattggcaat cctattgatt attttctggg ctattttact
     4621 ctcacagtta aaaggaacca aatacacttc attgattgct cggatcggtt ttgtagctgg
     4681 tatcttgttg ccagcattag tcttgtttgg cttagggatc cattatgtcg cttcaggcgc
     4741 tccactacaa acgatactgt ctatgaaaac attgattcct gatttttcga aattgcctac
     4801 gctggttgtt tttgtttcct ttattttagc atatatgggc gtagaaacat ctgccagtca
     4861 tgcaaatgaa atggaaaacc ctaaaaagga ttatccatta gcaatgtttg tattggttat
     4921 tctggcaatc attttagata cttttggcgg attgaccgtc gctactacag tacctcaaca
     4981 tggtttgtct cttaatacag gggtgattca atcgttagaa ttcctattaa gacacattga
     5041 tccaaatctt gcatggattg cgaaaattct tgcgattctt gtttgtttag gtgtcatcgg
     5101 agaaattgct tcttgggtaa cctctccttc aaaagcactt cacgtagcag cagaagaagg
     5161 attacttcct gaatattttg caaaagaaaa cacacacggt gttcctgctc atttgatgat
     5221 cgcaaatggg atcgttgcaa caatctgggc agccgtcttt acattaagcg gcggggggaa
     5281 taatctttca tttcttgcag cgatgtcatt gactgttgta atctacctga tgttgtactt
     5341 tatgtttttc gcgggctatt tgaagctggt ttttaaagat gacagtcttg aaagagccta
     5401 tcaggttcca ggcggaaaag ttgtaaaagt aatcgttgct tgtttaggtc ttttgacttc
     5461 actttttgct ttttgtatct catttgttcc acctgctagt atcgcagctg gacagcatgg
     5521 gatttatgaa acgattctga ttgtttctta tcttatcgtc ttagttattc catttacgat
     5581 ctacgcatgc cgtcataaat tccagcatgc agaaaaataa aaaatgaaag ctggttattc
     5641 aaatggaagt aaaagaatta gaacaattga ttggaaaaaa tttccactat tatcaaacag
     5701 gacaagtggc ggattacatt ccagcattag ctgaagtgga tcccaaacaa ttaggtatgg
     5761 cgatttatga tttggataca aaacaactga ttgagggagg agacgccgat gtgcgctttg
     5821 ccatcgaaag catgtcaaaa gttcccgtat tgttattagc aatcaaagac aacggaatag
     5881 aaaaagtctt tcaaacaatc aacacggaac caaccggttt tgccttcaat tctatcatga
     5941 atatggaaat caatcatcgc aaacatccaa tgaatccttt tgttaatgca ggagcgattg
     6001 caacaacctc gttgattgcc ggtaaagatg cagatgaaaa atttgagcga atcttgtcat
     6061 ttatgaaaga gatctgtgat gatcctaata tcacattgaa tgaagaaatc tatcattctg
     6121 aatcaagaac aggtgatatc aatcgctctc ttgcttacta tatgaaaggt aatcaaatga
     6181 tcgaaggaga cgtaccggag atactcgatg cttatttcag acaatgctcc ctcaatgtca
     6241 ccgctacagg catagcaaaa ttagctgctg tgctggcaaa taaaggaatt gctccttgga
     6301 atggcaaaca aatcattact gaagaaagtg ctacaatcgt caaatcaatt atgacaactg
     6361 ctggtttgta tgatgaatca ggagagtttt ccgtccatgt tggtgtacct gcaaaaagcg
     6421 gtgtaggcgg cgggttgatg gcagctgtgc caaatcgtta cggcataggt gtcttcagcc
     6481 cggcactaga tccatttggt aacagcgcag ctggtatcca attgttgaaa gatgtagtca
     6541 aagaactaga cgctgacatc tttgaataac cattcttgaa agaggctggg gtaaaagtcc
     6601 aaacggctca aagctaccta caatgaggct gaaattgtga gcttgtttga cttttgtccc
     6661 agtttctttt tttattggtt tttgaaaggg cttttctaaa taaaaaggaa acaaaaatac
     6721 gatttacaga tatgattaaa taaaatcata agaaaaactg gaggcgtgta tcaggaatgc
     6781 tggaaaatta catcgagcga aatatattta gaaaagtgta tctgtgtgaa caattatttg
     6841 aattccaaga aatagacatc gaacaaacag ctatttctct aagggtgact acaccaacga
     6901 tccttcacga tctagaaagt ctagccgagt gtctagaata ttgtataaaa gaacaagtaa
     6961 gagagaagca taagtataaa ctcgtattca aacatggtat tgctctttct gagctcacac
     7021 agtttctgta cggtcaatct tattttttaa agtttttaag ttattatttt aatggtatat
     7081 tcacgagtac agaactggct gatcttgaat ttatttcttt gagtaaagta tatacaatca
     7141 aaaaaatcgt attggatttt tttaaagaaa atgattattt gaaaaataaa gaaatcatta
     7201 tcccagaatt tgactcgcgg aacatcttgc tagctttagt acgttatgtc aattgggaag
     7261 gctatgaaaa taaaaatccg tatgtagaag aagcttgtaa cgagttgatt gattatgtag
     7321 agactcattt ttttaaaaga agatattcgg aagatgaaaa gtcctttatc atacgagaaa
     7381 tagagatcgc aatcggaaga aaggcatttc cccttggact gaaagaagaa gataagaaaa
     7441 gcgcagaaac gaagccgtta tttcaattag tctgtcaagg attggaagag caaaaaggaa
     7501 ttctagactt acaagaagaa gatgtctatt atattttttc tttgttcaac agtagaaatt
     7561 ataccaatga gaacatggag ctgttaagaa aagatttcga agttgtttat aaaaattttg
     7621 ttctcaatga cctatcactg aatgaattga ttttacagat tattagtatc gctgaaatcg
     7681 acgatgcaga aaattttatt ttcaagcaat cctttttaca atttgtccgt acgttgtggg
     7741 cagatggaca agtattttta ccggaaagga tctatcttct atcagaaaaa gaacaacttc
     7801 tgtacggaaa aattgtagaa atattggaag agtggaaaaa gaaaaatcaa atccaactaa
     7861 gatggaatga aaatttcatt cgaaaattcg tcaaaagtct ttctttgatc aacagtgaac
     7921 aagcggggag acaggaaata gaaatttttg ttgtttcaga aagttcagtc aaacaatttt
     7981 tttatcgaac ccaatttcat ttgtatgcgg aagaaggcat cgctgaaata aatcctattt
     8041 tatttcgttc attagaagaa ttgcctgatg aatgtctatg tgcgaaaaaa agagtggttt
     8101 tgtgcgatgc tgctagctat caaaatggat tagaaactga aaagacaaag atctatccaa
     8161 tctcattaaa aggtgcaaac atccatttgt atcatattgc tcaggaactt cacctattaa
     8221 aaaaacatat ttcttgatga gaccttaatt aggagacctt ctacaaagct ttttaattgt
     8281 ctgtagaagg tttttatttg agtcctgatt cgtgcgaaga tctacttata taacaagctt
     8341 tctctgaaat ttttttaaaa tgctattgac ttagagtcaa ctctaagtag tagaatagat
     8401 aaagtgtaac aaatctattt tcattaaaag aagatagtac ggaggagaga atgtattatg
     8461 agtacagtat tacatgtatt ggatgcaatc aatagccccg cagatgtcaa aaaattatct
     8521 gttgaggaaa tgaaacagtt ggcagaagag atgcgccaaa aaatcttgca aaaggacagc
     8581 gatgtaggtg ggcacgttgg tccgaatcta ggtgtagtag aattaacgat tgcgtttcat
     8641 tatgtatttg attcaccaaa ggataaaatc gtttgggatg tttcccatca gtcttatggt
     8701 cataagcttt taactggtcg aaaaaatggt tttgaaaaag gacattaccg tgaagtgagc
     8761 ggatattcca accaacatga aagtaaacat gactatttta cagtggggca cacatctaca
     8821 tctatcagct tagcaacagg tttagctaaa gcgagagatc tgaagaaaga atcaggaaat
     8881 gtggtagcat ttatcggtga cggctcccta agtggtggct tagcttttga aggattgaac
     8941 aatggtggtg ttttacaatc caatctaatc gtattagtaa acgataatga gatgtctatt
     9001 gatgagaatc atggcagttt atataaaaac ttagctgagc ttcgtcaaac caacggtaaa
     9061 agcagcaata acctatttaa agcaatggga tttgattatc gttacgtgga taatggaaac
     9121 gatctggaaa cggtgatccg tttatttgaa gaagtaaaag atattgatca tccgattgta
     9181 cttcacgtcc atacggaaaa aggtcgcggt tatcagccgg caatcgataa taaaatgaaa
     9241 tatcattggc atgtaccatt tgatctgtcc accggggagg caaagcaagt aacttctgga
     9301 gaaacattta atatgatcat catggattat ttggataaga aaatgcaaac aagtacagct
     9361 cctattgccg cagtcaatgc agcgatacca ggcgcctttg gactgaaaac attccaagaa
     9421 aaacatccag atcattattt tgacgtgggg atcgctgaac agcactctat cactttcgct
     9481 tctgctttgg cttctcaggg agtacgtcca gtcgtcttcc aatcaagtac tttcttgcaa
     9541 cgggcatatg atcaattatc acatgattta gcgatcaacg agaatccagt gattatttta
     9601 gtcggtggcg gaacgatctc agctagtgac cgaacacacc aaggaacatt tgacattcct
     9661 tacttatcaa gtatcccgaa catcaaatat cttgctccag caacaaaaga ggatatgatc
     9721 tctatgctag attgggcgtt cgaacaaaca gcgcagcctg tagcaatccg aattcctaca
     9781 catggtgtag aacatggtac agctatcgca aatgattata gtattccagc ctatcaaaca
     9841 gtaaataatg gaggaaaagt agcaatttta gctttaggcg gttttcttga attaggaaaa
     9901 gaaacagtaa aagcttttag aaaaaaagga atcgaagcaa cgttgatcaa tccaggaacg
     9961 atcacagaaa atgacgtaga aacattagat aaattaaaag aaacacacga attagtcatc
    10021 acattagaag atggtagttt gtcaggagga tttggcgaaa atatcagtcg ttattatggt
    10081 gattcttcaa tgaacgtatt aaattttggt gcagagaaag aattcacgga tagcgttcct
    10141 gtagggcagc tttatgaacg ttatcattta acaccaaaac aaatcgttga agatagtctg
    10201 cgtgtcttga atattcaata attcattatg ctcaccatcc agataattgt ttatactagt
    10261 atctggatgg ttttttcatt ataaaaagca aaggggtgga tgttatgtat cagcaagtag
    10321 aagaatatgt caaaaagttc caagaaaaat atcctagtta tcaatcagaa aaattaggtt
    10381 tcttttcatt tggggataca gaaaaaatgg cagacgagtt gagcgaacta gttgtaaaaa
    10441 agataaagac tggtacatca agtggttacg atctgtataa acaagagaat gagcctttac
    10501 caaaagttgg tcaattagac gtggtcctga atggaaaaaa tgaaccagtt tgtatcatca
    10561 aaaatataaa tgtgaccatc ttgcctttta gtgaagtcac gaaagagcat gcttggaaag
    10621 aaggagaagg ggatcggaca ttagcttatt ggcggaaagt ccatgctgag ttttttaaac
    10681 atgcttataa agaagcgttg aacatagaat ttacagaaga gaagctggtc gtatacgaag
    10741 aatttgaagt aattttcttt tagtaagaaa ggtctgctga aagaaatagc tcattattgt
    10801 ctcctgaata gaaaagggtt acatttttat atgaagctgt atttttatat aacattactg
    10861 gaggagatat tgtggataca ctggaacaaa tcaaaggcgg agtcgtcgtt tcttgtcaag
    10921 ctttggaaaa cgagccgcta cacagttctt ttattatggg gagaatggct ttggctgcaa
    10981 aagaaggcgg agcagttggt attcgagcaa atacgacaga agatatcaat gaaatcaagc
    11041 gaatcgttga tttaccggta atagggatta tcaaaagaga ttacgatggg tcagaagtgt
    11101 ttattactgc gacagaaaaa gaagtggaag aacttttgga gacgcaagca gaaatcattg
    11161 cactggatgc aacttctcgt aaacgtccga cagaaaaaac aactgctgaa cttgtccaaa
    11221 tgattcacga acacggtcgg ttagctatgg cagatatttc gacttttgag gaagcgcttc
    11281 aagcgcaaga agatggtttt gatcttttgt ctacgacttt agcaggctat acagaatatt
    11341 cacgaaagac gcagacacct gattttgatt tattgaatca aatcatagaa caagtcgata
    11401 tcccagtaat tatggaagga catactgact ctcctgaaca agtagagaaa gcatatgaat
    11461 taggtgcttt ttcagtcgta gttggatcta ttatcacccg tccgcaattg atcactaaaa
    11521 gatatgtcga agccgcaagt aaagcaaata actaaaaaac acgcacggca cagattcttg
    11581 acaaaaaaga aaaattgata gatagtttaa agcagattct aagaagatga aaaaagcatt
    11641 acttttcatt ttgtcttcaa gatctgcttt ttaacgaatt ttatagaaag aaggcgaaac
    11701 catgtttgaa cggagtcctt cagaattgac agaacgtgaa aattacaagt tgctgattgg
    11761 ttcagtcatc cctagaccag tagcagtagt aacgactaaa tcagcaaaag atatagtgaa
    11821 tatcgcaccc ttcagttact tcaatatcgt cagttcgaat cgacccatct tatccttggc
    11881 gatccagaga aaacaagatg cagtaaaaga cacagcaaag aatattcttg agacaagaga
    11941 agctgttatc catatccttg atgaggacaa cgtagaagaa gtaaataaaa cagcagccaa
    12001 tctgcctaat gaggaaagcg aactgtacct gactgacttg actttaactg attcagtaat
    12061 catttcagta ccagcattga cagaagcaaa agttcgtttt gaaacatcct tatatgaaca
    12121 tgtcgagata cggaataaaa ataaagtaac agctgattta tttttgctag aagtacagaa
    12181 atatcattta aatgaaacag tctatgatga taagacagga aggatcgatc caagaaaatt
    12241 gaatgctgta agccgtttgg caggaaatga ttatgcagca ataggagaaa ttttcacgat
    12301 tgcacgtccc gaataaaaag gagcactagt tatgttaaaa ataagctata aaccatcgac
    12361 agattcaaaa gaaatgaaaa aagaatatga aacagtgaat gattttctgc aagggcagta
    12421 cttagaagtt ccgccattgc aagaccattt tgtcgttact actgttactt tagatggtaa
    12481 ggaaatagaa atgccagatc aaacgattag cggattgttt aattacttta acaaataaat
    12541 atttattccg aaaagtgaaa aaacatataa aaaaacacat aaaactaaaa aattatcaaa
    12601 gaatcctggt gcaactgaaa gaatttgcaa cgggattctt tcaacttatt tgttattttt
    12661 ttctaaaaaa tattaaagat tgttaaattt cactatttca tttcaaattc cattgcctaa
    12721 tcattaggaa aagtctatca tgaactcgta aatagaatat agtaataacc ttgttaggtg
    12781 aggctcctat acaaacatag gctgttgccc agaaacgtcg aaagtcgcca atgggtaaaa
    12841 cagaaactgt tggattaagg ctttttccaa tagctaagaa tgttttcttt acgttgtata
    12901 gtgctaaaac tcggacgatg agatgatgct aggtcagaat tcttgttcga aaaggtttct
    12961 gaccttttct ttatattttt gtgactgact tatttgatga gacaaactcg ctcctcacct
    13021 gacaagtgga ttgctgtgtg aggaggagat gcggtgaaaa aagatcgatt ggtggatttt
    13081 gggtccttat ttgactttgt ccatgatcgg tcttttagaa gtatacagtg ccagttctta
    13141 tcgtttattg caagccgatg aaaatacaaa aagtctatta ttgcgtcaac taattttcat
    13201 atttttgagt tggagcgtga tcttcttagc tcgttcagtc aaactacact atttacttca
    13261 ccctaaaata gcaggatacg gtttagcctt atcgattttc tttttagtat tagtaagaat
    13321 agggatattc ggtgtcactg tcaacggcgc acaacgttgg atctctctgt ttggcattca
    13381 attccagcct tctgaactgg caaatctttt tttgattttt tatttaagct ggttttttcg
    13441 tgacggaaat agtagcccaa aagatctaaa aaaaccattc ctgattacag taggtataac
    13501 ttttctgatt ttatttcagc caaagattgc tggagcattg atgatccttt cgattgcgtg
    13561 ggtcatattt tgggcagcgg cggttccatt taaaaaaggg atctatctaa tcgttacttt
    13621 ttctgcattg ctgattggag cagcaggcgg ggtattatat ttaggaaata aaggttggct
    13681 tccacagatg tttaatcatg cttatgaaag gatcgcgact ttaagagatt cttttatcga
    13741 tagtcatggt gcgggctatc aaatgaccca ttcgttttat gcactatata atggtggcat
    13801 atttgggcgg ggattaggaa atagtatcac aaaaaaaggg tatcttccag agacagaaac
    13861 agattttatt ttttcgatta ttacagaaga gcttgggcta atcggtgcat tgtgtgtgct
    13921 tttcttattg ttctcattat gcatgagaat cttttgttta agcagtcgct gtaaaaatca
    13981 gcaagctgga ttgtttcttt taggattcgg aactttgcta ttcgttcaga cgataatgaa
    14041 cgtgggaagt atcgcggggc tgatgccaat gactggtgtg ccattgccat ttgttagcta
    14101 cggaggaaca agttatctga tcctttcttt aggaatcgga atcacgttga atatttcttc
    14161 aaagatacag gccgaagagt tggcgctcta tcgacctgaa aaacaataaa gagaaactga
    14221 gaaactttca gtttgaatta tcataaagta caatctttta tttttcaagc gagaggttct
    14281 tttagaaaga ggaattcgca atgaaagtat ctcaaaaaat catattatct attttgttac
    14341 tgcttacatt agtagttggc tatttttcga ttgagtttat ccatggattt tcgtctgcaa
    14401 aacagagttc aactgtgaaa aaggtagagc cgaaaagtat ccctaccaca ctaaatgtgg
    14461 ctttgattgg ttcagatgct cgttcgaaag acgaaaacgg tcgctcggat tcacttctgg
    14521 ttgcacaata caaccagaaa acacaacaag caaaactgat ctctatcatg agagattcat
    14581 atgtcgatat tccaggttac ggaatgaata agataaatgc agcttactct tatgggggag
    14641 ttgatttatt aaatcaaaca ttaaaggaaa atttcaaatt tgaagctccc tattatgcaa
    14701 gtatcacatt tcaagatttt atcgattgcg ttaatgaact gtttcctggt ggagtcaaga
    14761 tcgatgcaga aaaatctcta gatttagatg gcgtatatat aaacaaagga gagcaagtga
    14821 tggatggtaa tactttactc cagtatgctc gatttcggga agacaaagaa ggagacttcg
    14881 ggaggatcag aaggcagcag caagtgatca aagctatctc tcagcagctg aaagacgtaa
    14941 cttcaatatt caagctaccc aaagcggttg ggaaattact tggtagtatc caaacgaacc
    15001 ttccagaaag tgtgcttctg gattgtggta tggatttcct caaagacata tgttagaata
    15061 aacaggtata aatagtgaaa taaaggaatg acaagcaaga gaaggaggaa aaaatgaaaa
    15121 gaagtgacaa gcacggcaaa aatcgaacag gcgcttatat tgccggcgca gtgatcttaa
    15181 tagcagctgc gggtggcggt tatttttact accagcacta tcaagaaacc caagcagtag
    15241 aagctggaga aaagacagtt gagcaatttg tccaagcttt gaacaaggga gattataaca
    15301 aagctgcaga aatgacatca aaaaaggcgg caaataaaag tgcattatct gaaaaagaga
    15361 tcttagataa ataccagaat atatacggtg ctgctgatgt caaaggactt cagatatcga
    15421 atctaaaagt agataaaaaa gacgattcta cttacagttt ttcatataaa gcaaagatga
    15481 atacctcatt aggtgaattg aaagatcttt cttataaagg aacattagac agaaatgatg
    15541 gtcaaaccac gatcaactgg caacccaact tggtttttcc agaaatggaa ggaaatgaca
    15601 aagtaagcct gaccacacaa gaagcagcaa gagggaatat tatagatcga aatggtgaac
    15661 cattagcaac aacaggcaaa ctaaaacaat taggagtcgt tccaagtaaa cttggagatg
    15721 gaggcgaaaa aacagccaat atcaaagcga ttgcttcctc cttcgactta acagaagatg
    15781 ctatcaatca ggcgatttca caaagctggg tacaacccga ttactttgtc ccattgaaaa
    15841 tcattgatgg agcaacgcca gaacttccag ctggagctac cattcaagaa gtagacggca
    15901 gatattatcc tttgggtgaa gcagctgctc agctgattgg ttacgtggga gatatcacag
    15961 cagaagatat tgataagaat ccagaattaa gcagtaatgg aaaaatcggt cgctcaggtt
    16021 tggagatggc ttttgataag gatcttcgtg ggacaacagg tgggaaatta agcattacag
    16081 atgcagacgg tgtagagaaa aaagttctga tcgaacatga agttcaaaat ggcaaagata
    16141 tcaaattgac aatcgatgcg aaggcacaaa aaacagcttt tgacagtcta ggaggaaaag
    16201 ctggatcaac tgttgcgaca acgccaaaaa ccggtgatct tcttgcgctt gctagctctc
    16261 caagctatga tccaaacaaa atgacaaacg ggatctcaca agaagattac aaagcttatg
    16321 aagaaaatcc tgaacatcca ttcatcagcc gatttgcgac aggttatgct cctggatcta
    16381 cgtttaaaat gattacagca gcaatcggtc tcgacaacgg cactatcgat ccaaatgaag
    16441 tgttgacgat caacgggctt aaatggcaaa aagacagttc ttggggatct tatcaagcaa
    16501 cgcgtgtcag tagtgatgta tcacaagtag acttaaaaac tgctttgatc tattccgata
    16561 atatatatgc ggcacaagaa acgttgaaaa tgggtgagaa aaaatttcgt acaggcttag
    16621 ataaattcat ttttggtgaa gaccttgatt tgccaattag tatgaatcca gcacaaattt
    16681 ctaatgaaga tagctttaac tcagatatct tgctagctga tactggatat ggacagggcg
    16741 aacttctaat tactcctatc cagcaagcag caatgtattc tgtttttacc aacaatggca
    16801 cacttgtcta tcctaaattg attgcagata aagagacaaa agataagaag aatgtcatca
    16861 gcgaaacagc agtacaaacg atcgtgccag atctgagaga agttgtgcaa gatgtaaatg
    16921 gtacagcaca ttctctttct gctttaggga ttccgttggc agcgaaaact ggtacagcgg
    16981 aaatcaaaga aaaacaggat gtaaaggggc aagagaacag tttcttgttt gctttcaatc
    17041 ttgataacca aggttatatg atggtcagca tgttggaaaa taaagaagat gatgattcag
    17101 caaccaaacg agcatcggaa ctattgcaat acctcaacca aaattatcaa taaaaaattg
    17161 ctttttaagt acagtaaaag gactgtggcg ttatcgtcac agtccttttt tcaaataaac
    17221 ggttttcacg atgtctcttt cacaacttct ttttgattta ctcacacttc ataaactttt
    17281 tttgtaaaat atttgagaac aagtggagaa ataagtgtac ttaataaaat cacgataact
    17341 aaaggtgaat agtactgtgg ttcgatcaat tgactttgct gtccaatttg taaaatgatc
    17401 aaagccattt ctccacgcga aatcatacca gcaccgacca tcaatgaact atgttgagaa
    17461 aaaccggcaa tctgagcacc aaaataacct ccaagcaatt tggtcaaaat cgctacaagc
    17521 gtcaatatag aaataaagag tagttgttca ctaaagtcag aaaaatcaac ttctaatcct
    17581 acactgacaa aaaatactgg tataaatact gcatatccta aagcctctac attgtggtat
    17641 acttcttctt taacctttgt ctgactgaca gctatcccag caaaaaaagc accaatgaca
    17701 gagctaagcc caacaagatc cgctacgtaa gacattccta aacaaataac tagcgatacg
    17761 atgataatag aagaatttgc gtacactttt tctgcaaatg aaagtaggaa aggcgcaatc
    17821 catttgacta ataagaaaat aaaaacaaaa taaattagct gttcaatcaa aacaagcggt
    17881 aaagaagcat tgctagaagc ttcccccgtt agaaaagata ggctgaaact tagaactaaa
    17941 acgactaaaa tgtcatctac cacagaagca cccaaaattg ttgatccttc ttttgtattc
    18001 actacgttta gttcttttaa tacttctact gaaatactga cagaagttgc cgcaagaata
    18061 atcccaaaga aaatcgcttc atttcccgaa acttggaatg ctttgcctgt caaccagcca
    18121 aaaacaaccg ggaagatgat cccaagcaaa gcaacgaaca taccaggtcg gaaatatttt
    18181 ttcaaaagag ataaatcact ttccagacca gctaaaaaca ttaataagat cacaccaatc
    18241 tccgaaaagt catggactag aatatcaggt ttgacccaat tcaatccagc ttggcctagc
    18301 aaaacaccaa caagtaattg tccaatcact gctgggatac ctaatctccg cgagatatgt
    18361 gagccaatcg ttgttgaaat caatatcagg cataaaatac caataaattc cattctcatc
    18421 attcctttgt ataaaatata gcccgaactt agcataacat acattattga aaaaatagga
    18481 aaatatactc acaaaaaaac caacaatcca aaagattttt ttggattgtt ggtttttata
    18541 cggtctattt taataactaa aaatgattaa cgtatagtca tttttcttat tctgatgaaa
    18601 ttgataatct cctggatgcc catgaaaatc aaaataaagc cgaatatttg gaatagaagc
    18661 atcaaacttt tgaatggatt gaacaataag acgaatccgc caatcaacaa cagaatacta
    18721 ctataaacac tccaactttt agcttttgta ttcatgctga agaacaactg gaacaagctg
    18781 ttgatgataa cagctaatcc aagaagaatc ggcaggatag aaacgattgc aggtgcaaaa
    18841 gcatagacga tcagagctaa gatcaggaaa aaaagaccac tgaacagacc gatactccaa
    18901 gaacctgttt tccttttaaa acggtaagcc tcaaaaagat tcaacaaccc aagcaaaaca
    18961 agataggcgg tgatcagata accgataaaa tgaaaaacag cagaagggtt tagcacaatc
    19021 gcaatcccag aaataatata aacagcagct cttaataagg cgtatttttg aatattttgt
    19081 ttaatcgtct caaacatata agaaaacctc ctttgactta ttttaacgtg aactagtcat
    19141 tttaccaaat taaatgttac aaaatgagcg aaggagaaga atatctctgg aaaaatcaac
    19201 ttctgaggat cttttccatt tttttgcctt ttgctagctc atcgatcatt ttatctaaat
    19261 aacgaatttc tttcatcaag ttatcctcga tgtcttctac tcgtacacca caaacaacac
    19321 ctgtaatcaa ggaacgtgaa ggattgggga caggggcttc cgcaaaaaat tgttcgaaag
    19381 tcacttgttt ttgtagttga tattctagtt ctgtttggga ataacccgtc agccaacaaa
    19441 tgatttcatc tacttcctct tttatacgat cttttctctc cgcttttgct acatacatag
    19501 gataaacgct tgcaaaactt gtcgtaaaaa tacgattttg cgccataatc agtcaccttt
    19561 ctttttttca aattatttac tacttatagt atataagaaa aagagaagaa aaagcgatta
    19621 ttcaaaaaaa caaaaaggat tgtgacaaaa ttcttgtcac catccttttt tccgctctct
    19681 gactttttac aatcttcata gctcaagtgc gcatcagata atcgaatgct cctaaagctg
    19741 cagtagctcc tgaacccatt gaaacaatga tttgtttgta tggactatct gtacaatcac
    19801 cagctgcgaa aacgccgggg atattcgttg cgccattttt ctcggtcact atttcatttc
    19861 ttggattcat ttcgatcgtt ccatctagcc aatccgtatt agggagtaag ccgactagaa
    19921 tgaatactcc tgaaacagct agtgtatgca tctccatcgt acggcgatcg atataggaga
    19981 gagattctac ctgattcgta ccgctgattt ctttcgtcgc tgcatgtttg ataacagtga
    20041 cattcgcaag agagactagt ttatcctgta agatttgatc tgcttttaat tctggtaaga
    20101 attctagaac atatacatgt tttgctaacc cagccaaatc gattgctgct tcaacaccag
    20161 aattaccacc accgataaca gcaatctctt ttcctttaaa taaagggccg tcacagtgtg
    20221 ggcaataagc aattccttta tttttaaact ctttttcgcc tggtacattg atagaacgcc
    20281 agtgcgcacc tgtcgcgatg atggcggttt ttgctttaag tgatataccg ttagctaagc
    20341 caatattaat aaaatgttgc tctttattta aggaaacggc ctgttgattc atcataatgt
    20401 cgatagggta actacgcaca tgactttcta cttgctgcat caattttgga ccttctgtgt
    20461 aagaggtacc aatcatattt tcaatcccta gtgtttcaac gacttgtccg ccgaaagaat
    20521 cagcgacaag tcctgtacgg attcctttac gtgctgcata gatagctgca ctactagctg
    20581 ctggtccacc gccaatcact aatacatcat aaggttcttt ttcaaacaac tcttcttcaa
    20641 tcaaagggcc agtgattttt tcaacaattt gttcgatcgt catgcgtccg ctactaaatt
    20701 cttctccatt taaaaacaca gttggcactg ccatgatttt tttatcatcg atttcttttt
    20761 ggaacatccc accttcaatc atcgtatgag taatatttgg atttaataca gctaatatat
    20821 tcaatgcctg tacaacgtcg gggcaattat gacaagtcaa gctaacataa ctgtcaaaat
    20881 gcaatgtttg tgttattttt ttgattttaa gactcaaaga ttcactgatt ttcggtgccc
    20941 gtccactaat ttgtaacata gccagtaaaa aagaggaaaa ttcatgaccg agggggatac
    21001 cagcaaaaac gattccactt tctttgccaa ctggattgat agaaaaacta ggtgtgcgca
    21061 tcgaatctct tttttcccaa gagattttag gagacatttc tgctatttcc ttcgtaaatt
    21121 cagctagttt ttgactattt tcactattat ccaaactaac agaaaaaaca ataggagatt
    21181 caatcagtgc taaatattgt tcgagatttt gtttagtttc tttgtctaac atatccacca
    21241 cctaaatctt tccaacaaga tcaaaacttg gtttcaatgt ttcgccactt tctttccatt
    21301 ttgccggaca aacttcacct gggtgggtac gtacatattg agcagcgcga atcttatcaa
    21361 tcagtgcact agcgtcacga ccgattccat ctgcattgat ttccatagct tgaacgattc
    21421 cgtctggatc aataataaat gttcctcgct gagctaatcc ttgctcttca tccaaaacat
    21481 caaaaatacg agaaatctga tgagacggat caccgatcat cacgtattcg attttaccga
    21541 tagcatctga tgtatcatgc catgctttgt gagtaaagtg ggtatcggta gagcaagaaa
    21601 agacttcaac acctaaagat ttcaatgtac tgtattgttc ttgtaagtct tctaattcag
    21661 taggacaaac aaaagtaaaa tcagctggat agaagcaaag aatactccag ttccccataa
    21721 gatctttttc actgacttct aaaaattctc cttgatgata agcatgtgca ttaaattctt
    21781 cgattttttt cccaatcaat gacatagtaa aacctccaat aataattatt tatttataat
    21841 tattgtaatt tagttggagt tgcaaagtca atggatattt tgttatttaa taaagattac
    21901 tcaaaaacga aggttaatta taaaaataga agaggtcgca agaaaatgct actgctggaa
    21961 atactcggga taacgttgag taacagtttc ctgttctttc agcatcatgt gtaagtgcaa
    22021 tcccgtttga aatcgagctt cttctggttt tttatcaact aaagccttga gtaaatcata
    22081 atgttgttcc atgatcgttt cccatggaag cccctgaatg gtcactcgta accagcggaa
    22141 acgttctaaa tgggtattat ggtcatctaa ccagttccaa acttcttttc ttcctgcaat
    22201 ttcgaaacaa gcttcatgaa ataaattatc tgcacggaaa aaagcgcgtt cgtcatttat
    22261 tttgactgct ttttcttgtt cttctaaaat cgtttctagc actattcgtg tttgtgtgtc
    22321 caatttggaa caacattcaa tcatgatttg ctcttccaac tgttctcgga caaagcgagc
    22381 attttctgca gaaacaagat taattttgga aacatacgta ccactttgag gtatcgtata
    22441 cacgagttct tgctgacgta gttgaatcaa tgcttcgcga atgggagtcc ggccgatagc
    22501 aagatgttcc tccagtgcct tttcagatat tttccttcca ggttctaagt cagcatagat
    22561 aatttgttta cgaatcgctt gataagcttg tgattgcaag ctgcttttca tctttattcc
    22621 tccaaaatca tttctatgaa cgtagtataa cagaagaggt ctgaaaaaca atctggtatg
    22681 tcacattaac tagtaaattt gtataaatag taaaattttg gttgacatag cgatttttat
    22741 tgcataaaat tcacttgaat acaaaaacta atatgttagt ttaggagggg aaaaatgatt
    22801 gatttaaaca actggaggaa ctttatccct gaattatctc aaaaagaagt agaaatacct
    22861 cattttgacc gtgcatcatt aagagaaaat ggacaaaaaa atcctgtctg gatccatttc
    22921 ggtggcggaa atctttatcg aggatttcat gcagaaatcg ctcaacgttt agcggatcta
    22981 ggcgaattgt ccactggtgt cattgtttgt gaaacattcg atgaagaaat aattgaaagg
    23041 gcttaccaag attttgatga tttgattctt gaagtggtca tgccaagcag tggagagttc
    23101 gtcaaacgta tattagctgc gacagctgac agtctgtatt gtcatccaga ttgttctgaa
    23161 cactttgata agatgattcg acactttgaa aatcctagtt tacaattagt tacttttgct
    23221 attactgaaa aaggttatcg attgaaagat acaaataata aatatatagg accgattgca
    23281 gtcgatataa aaaatggtcc aaagaagcca tcacatacaa tgagtattct tgctgtgcta
    23341 ctttataaac gttttttatc tggagcttgg ccgattgcac ttgtctctac agataatttt
    23401 tcacaaaacg gtagtcaatt acgtacttct ttgctaacga tcgcaaaaga atggcaaaag
    23461 gaaggttatg tacaaaatac atttatccaa tacttatcga atgaagaaat tgttgcgttt
    23521 ccatggacga tgattgatcg tatcaccccg aatccttcct tgtcagttag caaaatgttg
    23581 gcaaaagagg gcttttcaaa tatgtcgatt ttccaaaccg caaaaggaaa taatattgct
    23641 ccatttgtca atacagagga catccattat ttaatcatgg aagatcattt tcccaatgga
    23701 cgtccgaaat tcgaaaaagc tggggtattc ttgactgatc gtgcaacggt agataaagca
    23761 gatacgatga aggtgacgac ttgccttaat cctttgcata cgtctttagc tattatgggt
    23821 tgtttactgg ggtataggag catagctgag gagatgaaag atccagattt atcgctgcta
    23881 gtttctgaaa tcgggtacaa tgaaggcctc ccagttgtgg agtctccagg tatcattgat
    23941 ccaaagatct ttctggaaga agtaattact gtgcgctttt ctaatccaaa tattcctaat
    24001 atgcctcagc gaatcgccac ggatacctct caaaaggtgg cgattcgtta tggtgagacg
    24061 attaaaaaat atatggaaat agaagttaaa gacccgcaga cacttgtatt cataccattg
    24121 actctcgctg cttggcttcg ataccttatt ggcattgatg atcaaggaaa accattcatc
    24181 ccgagtccag acccactatt gacagacctt cagcataagc tttccgatat tcaactgggt
    24241 acgcaagata catcacatat tcatgagaaa atggctccta ttttgtcaaa taaagaaatt
    24301 tttggtgtag atctttacca agcagagctt ggcagaaaaa tagaagaaat gttcatcaag
    24361 atggtagcag gaccaaatgc cgtacgaaaa acattacagg attacttaca agaacatgga
    24421 ggaaatttat catggaaatg acttttagat ggtacggatc acaggaagaa aagattacct
    24481 tagatgaaat cagacagatt cctgcggtca aagggattgt aggcacattg atggatatac
    24541 cagtaggaga ggtatggcct agggagagga tcaaagaact aaaagaagaa attgagtctc
    24601 gtgggttaac actaaaagta attgaaagcg tcaatgtgca tgatgccatt aaaattggat
    24661 taccttcccg tgagcagtat atcgaaaact ataagcagac aatccgaaac ttggcagaat
    24721 atggaataga agtcatctgc tataatttta tgcctgtatt tgactgggtg aaatctgacc
    24781 ttgactaccg cttagaagac ggctcatcca cgttagcttt tatatctgat gatattccag
    24841 atgatccaag agaaatcgtc gcgcgcatcg aacattccag caatgaattt ggattgccgg
    24901 gatgggaacc tgagcgctta gctcctatca aatccttgct tgaagcctat gcatcagtag
    24961 acgaagaaaa acttcgagaa aattttgcct attttctcca atcaatcatc ccaacatgtg
    25021 aagaggtagg ggtcaaaatg gctgtacatc cagatgatcc gccatactcg atttttggat
    25081 tagctcgaat cgtaaagaat cgagaagatt tagattggtt gtgtcgcata gtagacagcc
    25141 cttataacgg aatcactctt tgtacaggga gtattgcaga agatccagaa aatgatgtat
    25201 atgggatttt agcagaattt tgccaaagag atcgaatccc atttgcacat gttcgaaata
    25261 ttaaattttt agctaatcga gatttctatg aggcaccaca taaatccgaa tacggttcat
    25321 tagacatgta ccgcatacta aaaacaatgt atgacaacgg atttaacgga tacatccgtc
    25381 ctgatcatgg aagaatgatc tggaatgaga caggaagacc aggatacggc ttatatgatc
    25441 gagcattagg tgctgtttat ctaaatggat tatgggaagc aatcgaaaaa ggaaacaaaa
    25501 gtaaagataa ttagtgaaaa aaactgtaat tttattatgt aaataagaag gatgttcaaa
    25561 ttcttgatac ataaatccgg aggttgttaa taagcattcg gatttatgta tcttatttgg
    25621 tctaggaagt aacttgattt tcttttttcg attgatccat gagtgcttct tcttttaatt
    25681 caaagatata ttctgagatc ctcataatca cttttttcca gtcttctggt gtgatgattc
    25741 cttttaaaat atagattttt ttgatatgag aaggcaattg tttcaaaggg cagtcgctga
    25801 taacgatgtt gcagttctcc ataaaatcat tttgtatttt gatcgattca tttgaaaaaa
    25861 tttgttctat cttaacgatc agatctttac tgatataaaa atcacgcgta tagttcacac
    25921 caatcacaat tcgcggctgt tttttgtagc gatcatacaa atgtactagg tcttcaacca
    25981 tccattgcac attttccttt tctaaaataa ctggtaacaa gtgttgattt tgttctctga
    26041 aatccatata aaattgttca atggcggttt ggacttcttt caatacgcta tgttcttgat
    26101 aaagcatgaa agtaggaagg ggcgtatttg gttgattgaa gttaagaaat ccattataaa
    26161 gtttatttcg tgcgaatgcc aatgagtaaa gaatcttttc tttttcaggt ataaacaaat
    26221 caaatacagt acaaagggac tccaccattt ctcttgaata aagaacatga ggaacgtttg
    26281 ctttttttaa aagtttgtat tgctccaagc ttgtttcttc cgattcgatt ttcgtgatag
    26341 aaagtcgagc taaaatattc actaagatgc gttgttcgcg acaaattggc agattaggtc
    26401 gcaaaatatc tacagagaga tcaataaaaa agtcaatata ttcatactct gtgaattctt
    26461 tttgtacgtc tttcacagaa gttgcaggaa aattctcttt acatattttt aatagaaaat
    26521 ataatttatc tatcataccg ctatttagtc ggtcaagtac ttctttttta aaaaaagtat
    26581 tcatcataaa agccactact tgcggatctt catcataaaa ttctgtagca gtacttgaaa
    26641 agatgttcca ataaatatct aatgctgcat attgaatttg tacctctttt ccagaaaaag
    26701 actttctgcc attattagaa aaggagatag acaaaccgta ctatgctaaa aatgcattaa
    26761 tctttttcat tttcgtatac aaataagagg cactatagtt tgtttgctga ctgaaactga
    26821 taatcgaatt tgtctgacag ctgaacaaag aagtcaagat ctgataactg actgattcgt
    26881 tgcagtatct tccaaataga cgataatagc agtaagccgg atcaattcct tcaaaattca
    26941 actttaaaaa aggtttttgc ttatcaatat gcagttctgt tagattgaga cgctcaaagt
    27001 cttgttctaa ttctttgatg tatagtaaaa aatttgattc agacatatgg aaatgatctg
    27061 ctaaatattg tgtagtaata aagaaacgat gttcagatag gaaaagaaaa atatctaatt
    27121 ttgtattgct ttttttcttc aagataaacg ttttaatcgc ttcttgagtt tgcatgaaag
    27181 aggctccttt ttacttaaat tgttaaaact tgaaaatatt actgtttttt tcataaattt
    27241 agacaaaaaa acagtaaaca tataggtaga atctctacta tcttatttct tgcatacaaa
    27301 aaaatcaagg agtgagagag ttatgagata ttcaaccatc ttaatatcaa catttgcagc
    27361 cttaagctta tcgcttacta taaatcagac agtccacaca gaggagacag aaacagccaa
    27421 atggacagaa accaagtggg ccaacgtcaa tcgaattacc tttcaggatg aattttcatc
    27481 cttcaattca ggagtcgcaa aattaagaaa aggacaaaca gcgaccatca aagcaaaaat
    27541 tgactattcg ggagacttag cacctatact acaatcagct gttacatttg agaatgttga
    27601 tcccactttg tcgattggct atgacgagaa cactttgact atccaacaca agcaagcgat
    27661 atttaccttc accgttacat taaatcagga cttgttaaaa ccagcgcttt ttactgtcaa
    27721 ggtatcagat ggactaccga acgatcatca tttaacgccg tatagtcagc ggcagacaat
    27781 tgagcaagat tcagccatcg actcaggagg agatcttgtt gaagaaccaa cagataaacc
    27841 agaaaatgaa aataagccag aagtaccgcc tacagaaaat ccagacggag aacagaaacc
    27901 ggaaatagaa cctggagaag aacccgatac agaaactcaa ccagagccag acaataaatc
    27961 aaaacctgaa ataacccctg gagaaaaacc agatgtaact ccagaaccag atacggattc
    28021 tggaaaccaa acagtaccgg aaacaaatcc agacacagat aatgaaactg aaaatccaga
    28081 aaaaccagag gtagatccag aagaaaaacc agatgtgact ccagaaccag atacggacgc
    28141 aagagaccaa ggaataccag aaaaaataaa caaaaaaaca attcaagagg atggaaaaaa
    28201 agagagtaaa aaatcaaatc tagcaattct aaaaataaat gaagagcagc tgaataaaaa
    28261 atcacgaata tttgatagcg cccaatcagc tgaaacctta aaaagtagca aggatacaac
    28321 ctttgctgtc ctgaaacgaa aaataaacag ctaccaaaat ccggagagtc acaaaacaaa
    28381 gttatactgt ggagcggaat cattctatta agtatagcaa caatgctttc tgcaaaaaga
    28441 tttaaacaaa acagatctct ctaacatttg aataatgtct gtgaacgcat ttttcaaata
    28501 aaaagaaata tccagaaaat gaccccaaaa taccagattg aaatctgata tttggggtcg
    28561 ttcatacttt atctttcttc atatttattt taagggatat ctgtttcttt tggaagatgg
    28621 ttcgggatct ttttcacttt caatacatct aaaaagaagg taaagatcgg aatgccgaca
    28681 atcaagcccc aaacgccaaa gaaccgttcg ctaacaagta agaccacaaa tgtataaaaa
    28741 atcggcagtt ctgttttgct ggacatcaac ttcggattca gcacataaga ctcaattaga
    28801 tggacaatca aaatcgtaat caggatataa acaacatctc ggatgcctcc ttgggaataa
    28861 gctatgaaag atagaggaat acaagaaatg ataacacctg ctactgggat cagacttaaa
    28921 atgaaaatca tgatcgctaa actcagcagc tgatgaaagc caaatacagc caaggcgatt
    28981 gtagtgagca acgtatttaa aagagcgaca acaaattgag cttctaatac caaaccaaat
    29041 gtattgacaa acttatcggc aaaatagtaa atatcttgaa agaaccaaga aaattcactt
    29101 tttaaaaaca atcttgagaa tacaattgtt tttttctttt caatcataaa aaagaaactt
    29161 aagatgaatg acatagcaaa cgccactgcc atttttccta tatcctgtaa atagccaagc
    29221 gcaatcgaag cgccattttg aagctgttca aaaaaatcgt ttcgctcaat ataagtatgg
    29281 atatattgta aaacaggatc tgcatctttt ggctgatgct cgtaaaaatt aataacggac
    29341 tggatcatgt caaatgtttg atgaataagc atcgggatat actttgtgaa tgccagatag
    29401 ataaggtaaa cgatcagtgt ataaatcatg atagctaaaa cacctgtagg gattcggaca
    29461 aatcgctgaa tgatttgaac aagatgaatc atcaaataag taaagataaa tgtgagcaaa
    29521 atggttgtaa tcatacttct aactaagaaa agaacaaaaa cgacaaataa taaaacagtg
    29581 agacggcgta ttttttcatt cgccaaaaaa cgctgataaa cggtcaaatc gacaacctcc
    29641 aaataacaaa aaataaacac gttattcatt atatgatgga atatgaaaat aagaaagagc
    29701 aaaaagaaaa accgctaaat gacgttatct tatgagttgg ttttcctcat aaaatcgttc
    29761 atctagcagt ttcagccctt tttctggtct tgatgaaaat tatctagcat ttttcgggtc
    29821 agatgttgca gtgtatccaa ttcttcctgt tcaagtggaa gataagactt gatcttttgt
    29881 ggaatacctt ctgcttgttt ttgcaacgca gcaccttgag cagtcagcgt aacatttacg
    29941 attctttcat cacccgtttc acgctgacga ttaatataat ttttttctgc taactttttt
    30001 agtaagggag tcagcgtacc agaatccaga cacaaatcat ttcctagctc tttcactgaa
    30061 gtctttttct tttcccataa aactaacatc acaagatact gggtataggt aagattcagc
    30121 ggcttgagga ggggagtgta gtgtctaatg atttctttag aggcggcata taaaggaaaa
    30181 catacttgat taactaaata tagatcttcc atttttccac ctccgctgtt ttactatagt
    30241 gtatcatagc ggatttacac aaaaaagtct attcactaac tgctttcaga gtaacttcta
    30301 tatttccagc tgtagctttt gaatacggac acactttatg cgctgcctct aataattctt
    30361 gcgtttcttc cagagaaaga ccttcgatag atccttcaat ctctacacct aagacaaagc
    30421 tcgtttcact ttctgaataa agggaaactt gtgcactgac agtagaagcc ccagagatat
    30481 ttttttgctg tttgatcaat tctaatgcac tgttaaaaca tgcactgaaa ccagctgcaa
    30541 acaattgttc agggttggtt gcattttcga cgcgtttacc aggagctgca atattcaatt
    30601 cgaatgtacg atcgggatta tgcacttctc cagagcgtcc gcctgtgttg atcattttcg
    30661 tagaatacat ttttttcata aaattaccac ctttaattat attttataca attgaatttt
    30721 acacaatata attgtggaaa gcaaagaaat ggattggcat aagataaata agagaaagca
    30781 catgaaacag acgcgctttc tcgaatagca aacatataca aaaaatatca gagacaaaaa
    30841 ataatctcat cataaacatt acatatattt ctcaaaaagt tgttttcttt cttcaaaaat
    30901 tacttcacga tggacctgat gaagcatcca taaataacca aaaggatctc tgaacattga
    30961 gttagtcaca ccaaagtcca tcatttctgt catttcttga atctctacac agccatttcg
    31021 taatgcttta ttatgtgtgt cctcgatatc agagacgatg atattgaacc agatcgtatt
    31081 tggatgttca gcagtaggag cagtcaaacc aagagacgtg ttttcatcca gcatatggaa
    31141 tctcgtacca tacaaggtaa aaatgacttc attattgcct ctagggtaat ctgttgcctc
    31201 aatcagttgt atttcatcaa agattgtttg atacagttct agtgctttca aactatcatt
    31261 taatacaaaa tcgatttccg ttcctttatg cataaagatc tcctctcctt ttcagtcgaa
    31321 cagttactag attcttttat tataccagct aaagaaaacg cattcaaaaa aatagcggat
    31381 ttacttacca actcattcga ttggatgata agtaaatccg cgtcccatta cttctgctac
    31441 gctgctgaca atgacaaagg cacttggatc gatttcttct atcaatggtt tcattcggga
    31501 aaattcatga tcagtcacaa cgatcaataa aacctctttt gactttcgat tatacccgcc
    31561 ttttgcctct agcagggtaa ggccacgtcc aatctcagca cttaagcgaa ggcggatgtc
    31621 ttccaaataa tgttcactca tgaccataac agatttcttt cgattgatac ctgtttcgat
    31681 ataagtcatg acaattgaag tgattgcaat agataaaata gcataaagaa actcttctat
    31741 tccaaaaata aacagattaa gagaaacaac gaatgcgtct gtaaaaaata agccaatcga
    31801 agtattcaag tggaaatatt ttttaaaaat gaggggaggg atcgtcgtac cgccgctaga
    31861 agagttgttt ttatataaaa tcgcaactcc taaagcaaaa atcgcacttc caaaaatgac
    31921 agacaacaac cgatctgaag taatcattgt ttctggaact attgcaatga ttaaaggaaa
    31981 aaccaagctt ccgaaaagta ctttaaaaaa gggtttttta cctaaaaata gaagagctag
    32041 taccaacata acgatattca acactaaaat aactatagct cggtcaaagc ctaaagcagc
    32101 ttccagtaat attcctagac cgctgacacc tccagcagca atatgatgag gccctaaaaa
    32161 catattgata gcgactccta atatgaagag ggcaaaaata atcttaatgt atgtccatat
    32221 aaattgtctc gtttctttca tttattcact tccttaattc attaataata ctcttatctt
    32281 attataactt acttttcacc ttaagttaac tttaattaat aaaaaaatta ggctagtcta
    32341 aattattatg tttcattctt ctagaatata cttctacgcc aaaaactgtt aaaaaacttt
    32401 tactttagaa aattggagaa attgatcgct taagataaat tcaggacact aaatagtaca
    32461 ggaagtagac taaaactttt aaaagtttta agtctatcta tttggcaagt ttaaaaaata
    32521 aaaattcggt atcaaaaaac tgttaccgat aacatttttg aaagcgttgt cttttgcttc
    32581 tctatcactt atagtgatga cgtcatatta aaacacaagg aggaaatcaa tggatacagc
    32641 tgcaatttat catcgaccgg aaagtgaata tgcatttcta tatacgaata caagatttcg
    32701 tattcggctt cgtactagga aaaatgatat caaaaaagta tatgtgctat gtggagatcc
    32761 atataccata acaactgaaa aatggtatca aaaacaacga ccaatgaaaa aatgtctaag
    32821 taccaatgtt catgattatt gggaaattga agtgacgagc gaaacaagtc gcttacagta
    32881 tgcgttccat gttgttgggg aagataacac ggactgtttt tacggtgatc aaggaatttt
    32941 tccttatcga gaaaatgtga ttactgaacc aaatttttat tttcgaatac cttattttca
    33001 tcaaatcgat cgattcacta ttccagaatg ggtaaaagaa acagtatggt atcaaatttt
    33061 tcccgaaaga tttgcaaacg gggacaaagc aaatgacccc gaacacactt taccttgggg
    33121 aagtaaagat ccagaccgag aagacttttt cgggggagat ttgcaaggtg tgatggatca
    33181 tttggattac ttgacggacc ttggcatcaa tggcatctat ttttgtccca tatttaaagc
    33241 cacatccaat cataaatacg atacgattga ttattatgag gtggatcccg cttttggcga
    33301 taaaaaactt ttaaaaaact tgattgatga agcacataaa agagggatac gtatcatgtt
    33361 cgatgctgta ttcaatcata tgggtgtcca ttcaccacag tggcaagacg ttctcaaaaa
    33421 cggagaaaaa tcgatctata aagactggtt ccacatccgt tttttcccag tagattctta
    33481 tcagatgact gacttaccag aaactgctga aaatatccca tatgatactt ttgcttttac
    33541 tccattcatg ccgaaactaa atacagcaaa tccagaagtg caaaaatatt tgctggatat
    33601 cgcaacttat tggataaaag aattcgatat tgatggatgg cgtcttgatg ttgctaatga
    33661 agtcgatcat catttttgga aaaaattcag agaagcagtt acagaaatca aaccagacat
    33721 ctatatcctt ggagagattt ggcattcctc tcaagcttgg ctgcaagggg atgaattcca
    33781 tgcagtgatg aattatgcat ttacagattc gattaaagat tattttgcaa aaaagaaaat
    33841 cacagcttca caaatggtca gtggaatgaa tcatcagcaa atgctttaca gagatcaggt
    33901 gaacgaagga acattcaact tattagattc tcatgatact gccaggatct tgaccctttg
    33961 ccaaggtaac aaagaattga tgaagtctgt gatggccttt atgtttcttc aaaaagggtc
    34021 tccttgtatc tattacggga cagaaatagg gatgactggt gaagatgacc cggattgccg
    34081 caaatgtatg atatgggaga aggaggaaca agatctagag ctattcggtt ttataaaaga
    34141 acttgtttct ctaaggaaac agttgtctaa gattatttct gaaggttcta ctcagtggct
    34201 aatagtaaat gatcgtgaag ataagctcta tttcacacgg aaactagagg gacagatcat
    34261 ctatgtttac tttaatcagt caaaagaacc ttgggtagta gaacaggaaa atgaggtgat
    34321 tcttagtcaa aattgtcagt tgttagaaga cgggaaagca gagatacgac aatacggatt
    34381 tttgatcatg tgttgaaaac tgttaccggt aacaacaaga aagcgtttgc aaatgaagat
    34441 ttgtgcccat tataataagg gtgtaacagc acgttgaata caaaggagga aatgaagatg
    34501 aaaaaaagaa gtgtgaaaca gttgggttta gggttaatct ctttaggaat cttaggcgga
    34561 ttagcggctt gtggcaatgg taactcttca gcagaagggg aagccgatga aggaaaaacg
    34621 ttaacagttt ccgttgattc tggatataaa gattatataa acgaaataaa aaacactttc
    34681 gaaaaagaaa acgatgtgaa aatcaagcta gtagaaaagg acatgttcga tcagttggaa
    34741 tcattagcgt tagatgggcc tgctggaaag ggacctgacg ttatgatggc agcatatgac
    34801 cggatcggtg cgttaggaca gcaaggacat ctggcggaag taaaactggg aaatgaagca
    34861 gcttacgatg aaacagacaa agcccaagtg acttatgatg gaaaaatcta cggagaacct
    34921 gcagtaatcg agacccttgt tttgtactat aacaaagatt tagtcgatac agcaccatca
    34981 acgtttaaag atttggagaa tctatccaaa gacagtcgtt ttgcttttga gtcagaagca
    35041 ggaaaaaata caggattttt agctaaatgg actgactttt attattccta tggtttaatt
    35101 gcaggttacg gtggctatgt atttggtgat gatggcacaa atccttcaga tatcggtttg
    35161 aataatgcag gtgctgtaga aggaatctct tatgcaacag attggttcaa aaatgtttgg
    35221 ccaaagggaa tgcaagacat aaaaagtgca ggagacttcg ccagccagca attcatgtcc
    35281 aataaaactg cagcaatcat tgacggtcca tggcaagcgc aaacatacaa agaaaacaat
    35341 atcaattatg gtgtagccaa aattcctact ctaaataatg gacagcctta tcaaccgttt
    35401 ggcggaggaa aaggatgggt agtcagcaat tatgctaaaa acaaagacct ctctcaaaaa
    35461 tggcttgatt atgtaacgaa tcaggaaaat caagaaaaat tctttgaaat ggtaaatgaa
    35521 atccctgcaa accaacaagc tagggaaaca gcaaaggcta aaaacgatga attaacaaca
    35581 gctgtgattg aacaatatga aacagctcaa gcgatgccaa acatcccaga aatgggcgaa
    35641 gtttggacag gtgcagaaaa cttgatgttc gatgcagcat caggttcaaa aacaccaaaa
    35701 gaatccgcag atgaagcagt aaaaacaatc agtgaagcca tagaacaaaa atactgatta
    35761 aaatgataac cgtccatttt tataaaaaat ggaacaggtg cttcagataa aagtggcaag
    35821 agcgagatgg aaaattatct tgctcttgtt gccattatct taaaagcagt ttgcggttta
    35881 gcaagtttag agggggcatt cagatgcagc aagataaaac aagcaatatc aacgaaaaaa
    35941 aaatcacgct ttgttcactt attccaggga tggggcagtt tgtaaatggc caagctttta
    36001 aaggtatcgt ttttttcgcc atattcgtcc tattcattgg tcagatgctt ctgggcggat
    36061 ttcatgcatt ggtaggattg gttactttgg gaagtatacc aatggaagat cattcattat
    36121 ttattttgat tgaaggcact ttgcaattca tcattacaat cattttcttg attttttacg
    36181 gtttgaatct tttagacgct tatcgagtag cgaagatgcg tcaagagggc aaaaaaatca
    36241 atcggacgat gaaggaagtc atacataata taggtgatga aggttttcct tatctattga
    36301 cacttcccgc ttatcttctc atgattttta cgatcatttt cccagtccta gttacattgt
    36361 tcactgcatt tactaattat gacttcaatc atattccacc agccagttta attgattggg
    36421 taggggctaa aaactttttt agtatcttct ttttaagctc atatcgtaat actttttttg
    36481 cagtcttttc gtggaccgtg atttggactt tatgtgcaac aactttgcaa atcacccttg
    36541 gtattctcac agcggttgtt gctcaccaga aatttattaa attcaaacgt attttcggta
    36601 tcattttctt attaccatgg gcggtcccag cttttattac tatcatgagt ttttcgaata
    36661 tattcaacga tagcgtaggt gccatcaata ctcaagtgat tcctttcata aaccagcttc
    36721 cttttgtaga tatcagtgca atctcttgga aaacggaccc gaactggacg aaagtagcaa
    36781 ttatcttagt gcagggctgg ttaggatttc cctatatcta tgtgatggtt acaggaatct
    36841 tacaatcgat ttcagaagac ttatatgaag cagcaaaaat cgacggagca aatgcatggc
    36901 agcgcttttc aaacatcacg cttcctgctg tcttcctagt ggcagcgcca acatttatta
    36961 cacagtatac ggggaatttc aataatttct ccatgatcta tctgtttaac aatggcggtc
    37021 ccggaagcgt aggcggagga gctggttcta ctgatattct tatttcctgg atctataaac
    37081 ttacgactgg aacttctccg cagtattcta tggcttcagc aatcacgttg attatctccg
    37141 tcatcgttat ctgtgtgtca ttgctggtat ttaaaaagac aaatgcgttc aatatggggg
    37201 attaacaatg aaaaaatttc attcgagtgc tcgattccaa aaacgacttt ctcacttttt
    37261 tacttacttt tttcttttaa tactgtcagt cattatcatc tatccgcttt tgatcacagc
    37321 aagtactgcc ttcaagtcag gaaatattgc agcttttagt ttagatcttt caagtgactg
    37381 gactttagga aactttactc ggctattcag tgaaacactt tacgggactt ggtataaaaa
    37441 tacattgatc atttctgtcc taacaatgat cgtacaagtg actgtagtaa ctttggcggg
    37501 ctatacttat agtcgctatc gttttatcgg ccgcaaatca agtttgatgt tctttttagt
    37561 gattcagatg gtaccgacta tggcagcatt gactgccttt tatgtcatgg ctttcttatt
    37621 agaagcgctc gataagtact ggttcttgac aatgatctat ataggcggtg gaattccaat
    37681 gaatacttgg ctgatgaaag gatactttga cactgtacca atagatttag atgaatctgc
    37741 taaacttgat ggggcagggc atttcaggat ttttttccag attgtattac cgcttgtcaa
    37801 accgatgctc gccgttcaag cattatgggc ttttatggga ccttttgggg atttcatgtt
    37861 agctaagttc ctgcttcgaa cacctgaaaa tcagactgtt gctgtcggct tacaaacatt
    37921 tatttctgat gtgacaaacc aaagagtctc tctttttgct gctggggcaa ttttgattgc
    37981 actaccgatt tgtctattat tcttcttttt acaaaagaac tttgttaccg gcctgacatc
    38041 tggcggaaca aaaggatagg agcagagtat catgcaaaca tttccgttaa actatttttc
    38101 cgcattacgt acgccaactc aagtgtttgc gggacgcaaa ctattatcat ggcctaaatt
    38161 tttcttgata tttgtatttt tagtttcctt gatggtcatg cctgtgactc ttttttatgc
    38221 caatcagatc caagcgattc cattagaaca atttctatcc gttcattcgc tgatcgatga
    38281 acaaggaacc caaaaatttt ctgaacttga attatctgaa actgggttac aagcatcgca
    38341 acaaacgata gctgtgaccc ctgaaatttt ggtaggtgtg tctttatctg agaaacaaca
    38401 atccgatcat ggaactttta ttgattttga gaaggaacaa tgggtgatcc aacaaaagga
    38461 taaatctggt atacgccgct atacgatgaa ttatagccca tctttccaac cagattctgt
    38521 acgtacgccc gaagatttcc aacgattttt agaaagagaa ttttatgcca gtaatcgtcc
    38581 aacaatcatt ttatcttata gtttaagtct tggtcttgtc ctatttgtca tgacgagtct
    38641 cattttattc ggggcttcct ttttcttgtg gatgacaaga aaaagccaac tttcatccat
    38701 tcatacattc aaagagagtg caaatttgat gctgaatgtt atgggaatag gttccatggc
    38761 agcagcagtt gtagggttta tccactttga ctttatcttg atgctaagtg tccaaacaac
    38821 gataactgtc ttgctgcttt tatgggtttt tgtcaaaaca agattcaaag ataagcgtgt
    38881 cgaatgacaa gtttaagcga tttatgcgac aatgaatgtg aaaaaaatga aaaataaagt
    38941 agtttttgaa aaatttctga aaaaattaaa cttcttagtt gattcttttc ttttttagta
    39001 ttaacgtaat agggtagttt ttttaaggag gaaaatcatg ttagagaaaa ctttatacaa
    39061 tcaattattt tcacgttctt tctcgctccc tgtcgaagta aattattggg acggtacaac
    39121 gaaacaatac ggagatacgg acactcctcc ccaaatcaaa atcaatatcc atgaagaaat
    39181 cccaatgaaa gagattacaa gtaacgcatc tttggcacta ggagaagcct atatggatca
    39241 tcgaatcgag atcgagggaa gtatccaagc attgatcaac gatgcttatc agcaagcaaa
    39301 cagcttttta cgaggaaaag attatctaaa atggctgcca aagaaagaaa aacatacgaa
    39361 acaaaaaaac aaagaagata tccatgcgca ttatgactta ggtaacgact tttataaact
    39421 ttggctagat ccaactttga cttattcttg tgcttatttc aatacacctg aagatacgtt
    39481 ggaacaagca caaatcaata aagtccatca tatcttagac aaactcttta tcaaagaagg
    39541 cgaaacgttg cttgatatcg gttgtggctg gggaacattg atgttcactg ctaccaaaga
    39601 gtataatgtc aaggcaactg ggatcacact aagtgaagaa caatacgatt tgattaccaa
    39661 aagaataaaa gaagaacatt tagaagataa atgccgtgta ttattaatgg attaccgcga
    39721 actaaaaggc gaaacgtttg atcatatcac aagtgtaggt atgttcgaac atgtaggttc
    39781 tgaaaatctt gaaggttatt tcaaagtggt aaaagattta ttgaaaccaa aaggaacagc
    39841 tttgatccat ggaatcagcc gacaacaagg cggtgcgaca aatgcttgga tcaataaata
    39901 tattttccct ggcggttatg tccctggtgt tactgaatta gttgataata ttacaaaaaa
    39961 cgatttgcaa ctgattgatt tggaaagctt acgtcgtgac taccaattga cattagaaca
    40021 ttggacaaag aattttcatc aagtccaaga tcaagtcacg aaagaaatgg gtgattcctt
    40081 ctatcgaatg tgggatctat atttacaagc ttgtgcagct tcatttgaat caagtaatat
    40141 cgatgtgatt caatatttgc ttgttcaacc tggaaacaat gacatcccaa tgcatcgtgc
    40201 ataattgagg caaaagtact gtttaaagac tatttaaaaa gaagctaagt tttatgatgc
    40261 tccagaagtg aacttttttg tctaacttct aggattgtct ctaaagctta gtttcttttt
    40321 ctttatattt tcataataaa agtttggttc tttaattttt aaacatgaca gaaaattttt
    40381 tcttcgttat acttgtaata gaatactatt ttataacaaa ggggatcgaa tcaatgaaaa
    40441 aaactgttat ttatactagt ttatttgcag ctttgttttt agctgcttgt caatcaaata
    40501 ccaatcaagg cacatctggg aatacgtctt ccagtagcga acagcgctct tcacaggtat
    40561 cggactcctc aacaaaagca agcacatctt cgtctagcca gacaaaaagt tctagtgaag
    40621 caagtactca gtcagatatc aaagtgtctg cagctcgtgc gatcgaattg ttccaagata
    40681 aatacccaga tactgcaatt actagtttgg aattagatag tgattgggga tcttacttct
    40741 acaagataga aggtgtcgat gatcaaaaag aatacgaagc aagaattgat gctcaaaatg
    40801 aaaaaatgga gacagagaat ccagaaactc tagatcgaga tgaacaaaat ggtcaaaaga
    40861 aaaaagaaga tggtctggat gttgataaat tgatcacgat tgaggaagca gcaaaaatcg
    40921 ccgtcgacaa agtaggaagc ggtacggcaa cagattggga tttggataaa gatttaggta
    40981 ctacttattg ggaagtcaaa gtaaaagacg gcaatcaaag tacatcagtc aagatcaata
    41041 gccaaacagg cgaagtactg tcaactgaac aagatgatta agaatttctt cggaaaacaa
    41101 gagttgattt ttcttttagt catgatacac tagacaaaat aacttgtttg aaggagcgat
    41161 ttacttgagt ttagaaacga cctttgccaa tcatatcttt gccaatcctt tgatgaatgc
    41221 atctggtgtc cactgcatga ctacccagga attagatgaa ctggctcatt cagaagcagg
    41281 agcatttatc actaagagct gtacgatcaa tgaacgaaaa ggaaatcccg aaccacgcta
    41341 ttttgatgtt cctttaggga gtatcaattc tatgggactt ccaaacttag gtttttctta
    41401 ttatctagag tatgctcttg cgtatgaaaa agtgcaggaa aaccaaaatc aaccgttatt
    41461 tttttccatt gccgggatga gtgtccagga aaacttggaa atgcttgaga aaatagaaaa
    41521 aagtgggttt aatgggatca ctgaattaaa tttatcttgt cccaatgtgc ctggaaaacc
    41581 acaactagct tacgattttg aggccactta tgaaacactg aaagaagtat tcagcatctt
    41641 ttctaagccg ctaggaatca aattgcctcc ttattttgat tttgctcatt ttgatcagat
    41701 ggctgatatc ttgaatcagt ttccattgac ctatgtcaat gctatcaaca gtgtgggcaa
    41761 tggtttgtat atcgatacag aacaagaagc agtagtcatc aaaccaaaag aagggttcgg
    41821 cggcattggc ggagagtata tcaagccgac tgctttggcg aatgttcgcg ctttttatac
    41881 acgtttgaaa ccagaaatcc aaatcattgg tacaggtggg attcggacag gacaagatgc
    41941 atttgaacat ctgctatgtg gcgcaagcat gttacagatt ggtaccgagc ttcataaaga
    42001 agggccggaa attttttcta gaatcataaa agaattaacg cagattatgt cagaaaaagg
    42061 atatacgtca attgacgaat ttaaaggcaa attacgcacc atttcatagc aaagagacga
    42121 aggtcatgat tgatcttcgt ctttttttat aaaaaacact cgtctgttca ttcctgtgca
    42181 agcgtactca ttgtatgtta gacgaacttg tgggaaaata acagaggcaa aaaggaggat
    42241 aatatgaatg atgcaacaga attagcaaaa gagcttaaag aaaaagaatt tagttttcaa
    42301 gaactagtta cggatataca gaaaaaaata aagaagcaaa atcatgaatt gaatgcgttt
    42361 gtcgcgcttg aaccattcga gagtaattcc cacgagctat tgattcccca gtcagaaaaa
    42421 gggccattgg ctggtatccc atttccttta aaaatgctcg gtcaagaaaa aaagggatgg
    42481 ctagctactt caggatctcg tttatttgaa acacaccgag cttctcatac atctaattat
    42541 gtgcggcaag cagaagcgat aggtctagtt ccttttggac aaaccaatgc gccagagttt
    42601 ggtttcaaaa atattacaga cccagtcatc tatggcccag caagaaaccc ttggaacctt
    42661 gaatgtacac cgggcggatc aagtggagga gctgctgctg cagtttcatc aggaatcgtt
    42721 cctttagctg gtgctagtga tggcggtggt tctattagaa tacccgcttc gttttgcgga
    42781 ttgattgggc tgaaaccttc gcgagggacg atgccagttg gtccatatgc ttggagagga
    42841 tggcaaggag ctgctattga tttcggcttg acagtttcta tgagagacac ggaggcttta
    42901 ttttatggga tgagaagtat ccattccggt gcgccatatc aagtatcgcc agttgagtgg
    42961 caaacacatc caagaaaaaa acggttgaag atagcttttt gtgttgattc accgatccac
    43021 tcacagatta gtgaagaggc agtacttgct gtaaaaaaag ctgtagattt ccttggaaaa
    43081 gaagggcatg atttgacaga gattccttac ccactagatg gtcgtaaact gatcacgtct
    43141 tattatcaga tgaatggcgc agaaacagca gcaatgatcc gctcgattga aacaggcatc
    43201 cagcgagctg tcagaaaaga agaacttgaa cccatttctt ggactttgtt ccaatatggt
    43261 cagaagctct ctgccgctac ttacatcgat tctctgcatg tatgggatga agcagcaatt
    43321 gtcatggaaa acctacatca agaatacgat ctattccttt caccaacgac tgcatttacc
    43381 gcccctaaaa tcagcgaaga tttgcaaagt gatgcgataa gagcacagat ggaacacatc
    43441 agtgattgtt ctgaagtaga aggtttagac gttgtttctt ccatgtttga ggagagcttg
    43501 aagatcacac cttatacaca gttggctaat ctgactggac aaccagcaat cagcttgcct
    43561 actcatttga caaaagaaaa catgcctcta ggaatccaat ttatggctgc cagaggaaga
    43621 gaagatttgc tatttcaaat cggctatcta tttgaagcaa atcatcagtt ccatttacca
    43681 aatccatgga aatagcagaa acaaggagaa gaagaatgaa gaaaaaaaga ttgtttgctc
    43741 taataactag tgcctttttt attttaagcg cttgcggtac agctgccgct aatcaggaag
    43801 ataacagctg gagtaatgta gaaaaaaaga aagaattagt agtagcgact tctggcacac
    43861 tgtttcccgc atcttattat aatgatcaaa atgaattagt tggttatgat gtagatttgg
    43921 caaaagaggt ggctaaacgg ttaaatgtca aaatctcctt taaagaatac aacgtggatg
    43981 gacaaatcac ttctgtttca aaaagagaat cagattttgc tgcgaacgat tttggtatca
    44041 caaaagaaag agaaaaaaaa ttctcccttt cagagacttt caaatattca tttgacagta
    44101 tgatcgtacg aaaaaaagat gattcaggaa tccactcact tgaagatctt aaagggaaaa
    44161 aagcagctgg cgaacccaat actagctata tgcgtttagc ggaaaaacac ggagctaaat
    44221 tagtcacata tgacaatgcc acgaatgatc agtatttaag cgatgtagca aatggtcgaa
    44281 cagatgttat tctaaatgat tattatctgc agaaaatggc cgtatctgct ttaccagata
    44341 tccctgtaaa aatactggag aacgtttatt tcaatgaaaa cgaaagtggt tttttattga
    44401 aagaaggaaa tgatgctctg aaaaagaaaa tcgatggcgt attaaaagag atgaaagaag
    44461 atgggacgac aaagaaaata tctgaaaaat attttcaaac tgatgtttca gtcaaaccga
    44521 aagaaacgat ggctgagtcg gtgagtgagt gatgtacttt cctctaattg atttttccct
    44581 catgtggact tcacttcctt tcgtactgca aggcttggta tacacattag ggattggctt
    44641 cgtgtcgttt cttttaggaa atctggtagg gttgcttttg acagttttag gtcttttgga
    44701 ttggctgcct ctgaatgtat ttattcgttt ttatttatcg ttctttagag gcattcccgc
    44761 actagtcctg ctgtttctgt tatattttgg gttaccttat caattaagtg ccttaacggc
    44821 ttcagtcatc tgctttacga ttaccagcag tgcatttatt ggtgaaatct atcgaggatc
    44881 actagcaggc gtttcttcag gtcagtggga cgctggttta gcttctggtt tttctttctt
    44941 tggggtattg aaatatatcg ttttgccgca agcttttcga atctcagtac cggcactcag
    45001 taacgtagct atggatctag tgaaaggtac ttcgttagca gcaacaatca cagtgccaga
    45061 aatatttcaa aaagcaaaga tcataggcgg tcggacattc gattattttt ctctctatat
    45121 tttagttgca ctgatttatt gggtcatttg tatcgggatc gaaaaagtgc aacagtattt
    45181 agaaaaacgt tctatgcatc agtcaatctg aaaaatagaa atggtgctag cgtggctggc
    45241 accatttcta ttttttgttt cttgtatatt ctgcctagta ttttaaaacc atttcatgta
    45301 aaatgtaaat cgaaaatatg ttcggaggta gaaaacatga agaccccgct aaccatcgaa
    45361 atagaatcct cgttatacca atattgcatc gagcaaggcg gcttggttgt agaagaagtc
    45421 acgatgcctg atgaccaagg aattgtagat acgcttagct gcttgacaaa atttgatgga
    45481 agccgagaat ggcgatgcta tgagctgaaa gtgacaaaag cagattttcg ctctacagcc
    45541 aaactgtcat ttgttggaca ttataattat tttgttttac caagtaaact atatgaagaa
    45601 gtaaaaactg aaatccctac aggaataggt gttttagtgt atcgtccgta cacggttgaa
    45661 gaggagatgc ctgcctctgg tacatttctg attgcgaaaa aagcagcaaa gaaagagctt
    45721 gctgtaccgg aagaagcttt gacaaaccgc ttcatggctt ctttattcag ggaagtaaga
    45781 aaagcaaagc aaatggagcg aggcgtaaaa tattttccaa cagatcaatt gtacaaagaa
    45841 ttgaaaagac gttcagaaaa tcaagatcca ttttctaacg aacgatatta tgaacggttt
    45901 ttagaggaaa tagctagtca ggcaatcaat gagttgcaag aagaagttat cgcgcttcag
    45961 catgattatg aatatttgag gcaacaacag cagatccgtc ggttgcctac agagccattg
    46021 gagtgaaaaa tatgtactat ccttatttaa gaggaaaaca atttgaccta ttagcattaa
    46081 aagaagcact gtcgcgagga ttgctctcca ataaaatcca accagtgatc gaaccagtac
    46141 gtgattccgc tacgcttaaa aatgtgatcg aattatttca aaaaaagcac catcgaatcg
    46201 ctgtgatcca aaatccccaa gtaggacaat tcaaattatt cgatcagcat gtgcacagtt
    46261 ggacagtcaa agaaaatagc tctgtcgtcc ctgcacagat cttaacgcca gaaaatctca
    46321 gtgaagtact ggattcacct ccagcgtttc ttgttttcga tggacagcac tacccaaaag
    46381 atacagaggt gtggaaacag ttggcaggag ttgattcgaa atttttgata ccagatacta
    46441 gtcgctttcg catctggctg cccgaaaaca aaattgtgat ccgtgactct tttcaaacga
    46501 gaaagcatgt tgaaagttat gcagataaaa cagatgactt ttttagtgat gactatcttt
    46561 ttttccacgc agacggatat attggatttt ctgatttcac gatcgaaggt agccgttatt
    46621 tcgataaagg gttccctagc cgagcgcttg ctatccatct aacgtatatt gatgcttacg
    46681 gcaatatacg cgtgaaacat tttgtctctg acagtaacga ctctgctaaa gaccaagcat
    46741 tgaagtttct tgaagcagga gataaaatga aaaaatggat catgcgtcac catcatcaac
    46801 tcttgattac ttcaggaatg attgaattat tggctcttta ccagcaacaa aaattccctg
    46861 gactgggagt gttgaaaaag tggtcactta tgcatcattt ggaacttatt agtcacctgc
    46921 tagatcatcc aaaagattgg cttaaatatt attcaaaagt tcaggaacta tatgaagtga
    46981 tccaatgatt agataatgta aatgaaaaag gaatagaaaa gaggaaactg gatgtatatt
    47041 cggcaaacaa ggaaagaaga agtagaagaa gtggtagaaa tcattaatgc cgcagcggat
    47101 ttcattgctt cgcaaggctc tcctcaatgg caaaacgggc agaaaccaac aaaagaaacg
    47161 attttgaacg atattgaaag aaaagaaagc tatgtattaa tagtggaaga tcaaattgct
    47221 ggaacagctg cattagtctc aagcgtggat cccgtttaca caaaaataga tggtagttgg
    47281 aaagaatcaa ctggtcctta tttatcgatt catcgtgtcg ctttagcaga aagtactcga
    47341 ggaaaaaaac tagcaaaacc gttcttagaa catttgttga cgattgcagc cagcaaaaat
    47401 atccaagata tccgtatcga tacttatcca gctaatgaac cgatggaaaa gaccatctat
    47461 tctgctggat tcacttatca agggatgatt gaatttcctt ttgaacacgg cgaaagaaaa
    47521 gcatatcaaa taatcatcaa ttgactataa aatcatctga gcaaagataa agacattaac
    47581 actactgaaa aaaacaatca tatgatagcc aagaggttgt aacagaagtg gccagcttca
    47641 aaaaacaaga aagaatttcc gaaaatgctt ctcaaatttt tgtggaattt tagcgtattt
    47701 tacgaaatag ctgctttctg aaactccctt catcgagagg tcgtgacata gcttttgtca
    47761 cgacctctcg gcttatccta cgagtattat tcgatacatt tatatcaata atcctttttt
    47821 tattttatct gcagcttctt ggaacgctcc atcgtttgac acgactaaaa gtgaggggat
    47881 agctttcaaa cgtttcaact gtgctaaatc ttctacataa accgccagtc tggctgaaat
    47941 ctgttcagat gaatctccac gttttttcag gcgcgattgc aatgtttctt tagagatcgt
    48001 aataaagata ggacggacta ccgtcccgaa atactcatat aaatgccaaa aaccatttgc
    48061 tgtcaaaacg gcgtaacaat ttcctactgt cagtttcttt ttaatttctg ctttactgga
    48121 accatattta tgttgagcat attggtccca ctctgcaaac tcatttccct tgatcatctg
    48181 attgaatgta ttgtcagaaa caaaataata atcctcttga tctttttccc caggtcttgg
    48241 tgatcgattc gtgtaagtaa tgatcttttg ttccggctga aaaatagctt ctgcgagtga
    48301 agtttttcca gaaccagaag gaccgataaa tacatagcaa taattcattg tcatttctcc
    48361 tttgatgatt gaacaagtga aaaagctttg gaaaatattt ccaaagcttt taaaagtaac
    48421 tttgcttttt tgtatattat accagcaagc cagtcacaat agcacttaaa aagctgacta
    48481 aagtcgctgt tagcaaaatt ttcaatccgt gttttgcgac aagatttcct ttttcttcat
    48541 ttaatccctt catcgcacca gaaatgatcc cgatagaaga gaagttggca aatgaaacga
    48601 ggaagacaga tataattgct gttgtacgct cagtaaaatg gaaattacca tttgctaatt
    48661 ctgtcatagc aacaaattca tttgtaacca gtttagtcgc catgatacta ccggcatcca
    48721 ctgcttcttt ccatgggatt ccgctgatga aggcaagagg ggcaaagatg taacctagga
    48781 tctcttggaa agtgatgccg aatatcccgt ggaagatagc attgatcatg gcaatcaaag
    48841 caacaaaacc gataagcata gcagcaaccg tgatcgccac atggaaacca tcaagaatgt
    48901 attctcccaa catttggaaa aatgtctgtt ctttgttttc ttcaatgatc agctcatctt
    48961 ctttttcttc taatacatag ggatttacaa ttgaagccag aatataaccg ccaaataagt
    49021 tcaaaacaag ggcagtgatc acatatttag aatcgatcag tgccatataa gatccgacga
    49081 tcgacataga aactgtagac atagccgata cactcatggt gaacaaacgt ttctcagata
    49141 ggaagggtaa ttcctttttt atggaaataa aaacttccga ttgtcctaaa atagcagaag
    49201 ctactccatt ataagattcc aatttgccca tcccgttgat tttacttaat cctagaccaa
    49261 cagctttcat aaataatgga agaatcttga tatagcgtag aataccgata atagcagaaa
    49321 taaatacaat tggcatcaat acggaaagaa agaaaggtgc acttccttta tttgctacac
    49381 cggcaaaaac aaagtcaaca ccttgcccag caaaagcaag aagatgatca aacatttttg
    49441 ccaatacaga aacaaccgct gtaccaaaag ttgtacgtaa taatacgaaa ccaagaacaa
    49501 gctgtaaaac gaacatcaca attagtggtt tcaatttgat tgcttttttg ttactgctga
    49561 tcaaaaaagc aagccctaat gtgacaaata aaccaataat acctaataaa taactcaaat
    49621 aatcactcct attccaaatt ccgttttatt ttacctgttt tgcaaataaa atactaatct
    49681 ttagtgaaat tttcattact tttttagagt gaaacgcatt cattttccat tagaaaataa
    49741 agcgaacaaa ataaaaggtt taaaaagtgt aacgtcttag taaagtctat aaaaaaacga
    49801 aactatcgat taagctaata gtttcgtttt caacatttat aagtaaactt tttctattgg
    49861 taatatagat tttcggaagg gtagacaggt gcgcaggtaa tatcgattcc tagttttttc
    49921 aatgtttgtt catcattttt attgaccatc acagtagagt gggcttgtgc tccctcaagt
    49981 tcagctagtt tatcataagc aacttgagcg attggattcg ttactgcact gattgataaa
    50041 gcgatcaaga cttcattgat gcttagtgca tccaaagagg aatgaagtgt ctttgatttc
    50101 aatccttgta ttgtttcaag aactaatggt gacaataaag gaatgtcatc tgcgatatgg
    50161 gctaaatgtt ttactgcatt taagataact gccgctgacg catccatcaa tgaacttgta
    50221 cgcccggtaa tgatgacttc atctggtaat tcgattgcaa tcacagcaga aggatctttt
    50281 gtaggacttt gcgcttgaat cttatctgca tagtcatggg cagggactac cacgtttcgg
    50341 tcttcaggac gtaaaccgac ttcttccata atcagtttga ttcgattaac tgcttcttcg
    50401 tcgatcaatc cttttttgaa gtcgcattct gtttggaaat aacgacggat gatttcttgt
    50461 ttagaggctt cttggacaac ggtatcatcc acgatcccaa atcctacacg attcacaccc
    50521 atgtcagtag gagattgata aacagattct ttaccagtaa ttttttcaat aatacgtttg
    50581 attacaggaa atgtctcaac atcccgatta tagttcacag ctactttatt gtaggcatca
    50641 aagtggaagg aatcgatcat attgacatct tttagatcga ctgtggctgc ttcataagca
    50701 atgttcagcg gatgtttcaa cggaacattc catactggga aagtttcgaa cttggagtaa
    50761 ccagctgcat gtcctttttg gctttcatga tacagttggt tcaaggaagt agcgagcttt
    50821 ccacttcctg ggccaggagc tgtcactaca acgattggtt tagttgtttc aatatactca
    50881 ttttttccaa aaccatcttc tgagacgatt ttttctacgt tgactggata gtcttcgatt
    50941 tctgagtgtt tatagacctt gatgtttcgt ctttctagtt tattgataaa gactttcgtg
    51001 gcaggctgtc cactatagcg agtgataacg acactgttga ttaataagcc ataaccacgt
    51061 aattcatcga ttaaccgcaa gatatccata tcataagtaa tcccataatc accacggatc
    51121 ttattacgtt caatatctcc agcatagacg caaatcagta tttcagcttg atctttcaat
    51181 ttttgcagca atttgatttt cgcatcttct tcaaatcctg gaagtacacg tttcgcatgc
    51241 ttgtcgtcaa ctagcttccc accaaattct aaatataatt tgtcatagtg gttcactcgt
    51301 tccaaaatat acgctgactg ctcttcaata tatttttctg aatcaaaacc aatttttttc
    51361 actaggttcc ctccttaagt actaaagcat tttttcattt ttttgaggat tcgtcaactg
    51421 gaagagcgaa attcctcaaa aaaacaaaga aaatggttta aaccaacttg tctagatagt
    51481 tattcattgg tatgatagtt tttgataagg aaggtgctac atgaaaaaaa gacagaaaaa
    51541 gaaaaacgca tataaacact atatccgttc gatttttacc ggttatgaaa gaatgcttga
    51601 agatcccgaa ttggaacaat tgacgtttac ttatctaaac gaagaaacgc agctaactcg
    51661 tgatgagcat cagcgcattc atttcacaac aagagatctg cctagtaaat aaaaaataag
    51721 ataaaggtca tcggattcga ttctgtccta tcagatggaa agactagttg atcgaaaaaa
    51781 aggctgtacc aaattttggt gcagcctgtt ttatggagca ttgcccgctc ttttttataa
    51841 caatttttta cagaaaatgg tactattgaa gtattaataa gtgaaaaaca gatgagtaag
    51901 aggaggcaag tagtatgaaa gagccagata caaatgcaaa ttatgagcca gacgaactag
    51961 aggagacgaa tgcggatcag gatacaggac aagaatcgtc ttctttttac gatatcaaag
    52021 aaaaagcaag catgaatctt tcccaattat tagaagactt acaggctttt gaaaaagctg
    52081 tccgcgaaga agatatccct gagatctacc gtttatacaa tggccgattg aatgaagaat
    52141 taaaaagaag ctcaaatgaa aatcacgaga tcgatcaatt gctgatgcgt aagatccatg
    52201 atcgtttttt acaggaattt ccttttatgg aacaagtaga aaacatctcg ccaacgatga
    52261 gctattacaa aatcggcact tattaccatg atcggcccac ggtcggtatt gatgcaagtc
    52321 tgccagaaat ttttgttttg cctaagatcg atgaagagtg ggagaaatat tcccaaccgg
    52381 agtcaacgga ctatgacaaa aaaatcaatg agctagacgc aaaggtgatc actgctcaga
    52441 cagaaattga acgtttagat gaacaaataa aagaaatcaa tcgacaaatg actgatttga
    52501 acgacaataa aggattcttg aatcgtaaaa aaatcgagga agaaattcaa gaattagaga
    52561 agaagaagca agtactatct aatgaaaaat taggctggct tccttatatt gagacgcctg
    52621 aaacaatcca gcagcaaaaa gaagcattga agcaagaagc aagagcagac cagcttcgtg
    52681 cagccatcgt agaaaaagaa caaaggcaaa tcagacgcta tttcggtagc aaagagggat
    52741 tcggtcaagc aatccatgaa ttcttgatga attatcttgg caatgagaat cctaataatc
    52801 aatctaatga aggaggttcc gagtatgaat gaacacgatg aagcagaatg gacaaaaaat
    52861 gaagaacaaa cagaagatca tgaagaaacg aacacttcat tggaagaaca aacaagtaat
    52921 cctctggatg acacagaaga aatccctatg ctagaggaaa caaaaataca cgaaaaagaa
    52981 aaagtaactc cgacgaatac gaatactgca gaaaacaccc atgcttacga aataactgaa
    53041 aatcccgggt atttagaagg aaaagagcaa gatcatcaag atatcgtcag tttgattgaa
    53101 acagcggaag cagaattagc ggatttacgt atgagaaaag atttgatcga atcagatttt
    53161 ccacaattat tagaatcata tgatcgtttt atattgaatg aagaaccaat ctccacgatc
    53221 ggaaagacaa gcctgatcga atacttcacg tatgaattac tgaaaccgtt gaatgatatt
    53281 ggtctggaac ggtcaaattc agcttatgac acatggaaaa caagacattt ttcgatcaat
    53341 tatacgttga atggacaaaa cgaattagtc ttttcctttg tattaccgac catcgatcaa
    53401 cgataccaag tggaatcgat gagtctccta aacgtatcac cagagacaat ggaaatcaat
    53461 gtccaagatg accgggtgct ttctttgatc cgacactggt cagtggatcg agtattctct
    53521 gcagggcaga tcacgatatt caatcacaaa ttgaatcaat tattagccca tgcaagaaca
    53581 cttggtttta ccgttaatca gacattacta gacaatacga agccacttcg tttgaatctt
    53641 cagagcgaat ttgaattgac gaatgaagta ttggatgata tttttatcgt ggcaatgaaa
    53701 aatccatcct acgatatgga aaagatcaac gaaactactt atcaagtacg attagataaa
    53761 ggacagtctt taacgataac aacaaacgaa aaagatcaaa cagtcttgtc gatctcatct
    53821 ggagactacc cacgatctgt cattgatttc tttatcaatt acgaattctt ggtcccatta
    53881 atggtgagaa agtcctgatt ggataagttg gattaccaga tgtcattcag ataattctgt
    53941 tccaaaggac ttgcggcagt tatccagaat aattgtcaca agtcttttct gtatgtacta
    54001 aatggacgtg aataacttgc tgatgaagga gggatttcat taggaatgtc cacaaataaa
    54061 atagcacagc ttagcttatt gtctgctgct tgtgtagcag gtaggatcgc ttttcaattt
    54121 attccgaatt tccagccaat gactgctatt tttttattta tagtacttta cttaagctta
    54181 aaagatgcgt taattgtcat gagtctttct attgcgatca gcagttttta ttttggtgtt
    54241 ggaccatggg tcatcggcca atggatcagc tatactgttg ttctgagttt gttttcaatc
    54301 gtctgcttga gaaaaacagt gcaaaggaat ctatggttaa agggagtctg tttttttctg
    54361 gcgggcatgg tttacggaat aggtatgacc gtttttgata cgctgttata tcgtttgcct
    54421 caaccttgga tctattacct tcaaggggtg tcgtttgatt tgatgcacag tataggcaat
    54481 gttgtgttct ttcttgtttt tctgccagtc gtcaaacgtt tttacaatca ttcaggagga
    54541 aaaaatgaaa aaaataattt atagtttgct tgcaatgagt gtcagtatac tcattttgac
    54601 aagttgcagt acaacctata cacaatcggc ttccaaccaa aaggaggaag taaaaacatc
    54661 gcaaaaagca acaatcacgt tacaagaaaa tggtcaaaac ttttcggaaa aagaagtgtt
    54721 cttcaaaaaa ggcgatgatt tactgagtat tttgaaacga aattttgaag tcaaagaaga
    54781 taacggcttc atcacttcgc ttgaagggca ctcacaggat gagaaaaatc aactctattg
    54841 gatgtttact gtggacggga aaagtgctac tactggtgcc aaagagatca aattgaatga
    54901 tggacaatcg gtcattttca atttgtctaa actataagtt tcataaaaaa ctgttaaagg
    54961 gcgaatattg ccataattca gtgagttcag ttgatgaaag aaggaaaata acatggaaaa
    55021 ttttaaaaaa agcggaatgt tttccgtaat tgctgctcta ggggctaata ttctagttgc
    55081 tatcagcaaa tttgtcggct atgcaatcag tggcagtgcc gccatgctaa acgaaagcat
    55141 ccacagtatc gttgattgca gcaatcagat tttgctgtta ttcggtgata aacaagccaa
    55201 taaaggacag agcgagttgc atcaatttgg tgaaggacga gcaaaatact ttttcagtac
    55261 aatcgtcgca atgatgcttt tcttcggcgg tggggcactt ggggtgatgg aagcttttga
    55321 aaagttgacg catccatccc atgaagtggg taatccgatc attgttatag caatactgtt
    55381 atttggtttg gtaatcgaag gaagttcgtt acgcgtggca atgaaagaaa tcaaagaatt
    55441 gaatactgaa aaactttcca cgatgcgctt tttgcgcgaa agtcgacaca gtgaaatact
    55501 gattattttt acggaagact tgtgtgctgt aatcggtttg gtcttggctt tagcaggaac
    55561 aatattgact tatgcaaccg ggattgctgc atttgatgcg atcagcggat tgctgatcgg
    55621 tttcttgctg atgggagccg ccattttcct agcaaaagaa ttttatagtc tgatcatcgg
    55681 tgaaagcgtg acagcaagcg atttatcaaa aatcaagtta gcttttgaac gtcctgagat
    55741 cagtcggctg atcgatataa aaacagttca tttaagtcca acggagattt tagttgcagc
    55801 aaaagcagat atcgttggta acaaagagaa tgaagcttac tcggtcatca atgatattga
    55861 aaaaaatatg cgtcagtctc ttcctgacaa gaagatgtat atatacattg aaacagataa
    55921 atatgaccca aattattctc gtaaataaaa cgtttattca tgaattgaag caaaaatgag
    55981 aaaaatataa tcttgttttt aaataaaacg gctacaattt agcgaattta tgttacaatg
    56041 agtccgctgt ttatttgttg taattaaagg agatatttta atgaacaaaa agaaaagtgc
    56101 gccatggctt caagctttgc atgcagtgat gccactttgt ataagctata taccagtagg
    56161 attagcttgc ggagtattgt tgcaaaaagt tggatttgat cctctcttat caggactgtt
    56221 atcgattctg gtcttttccg gtggcgcgca gtttttagtt gcatctatgc ttacgacgca
    56281 agcatcattt gcaacgacat tattgatggt tttcttttta gaattacgct atacattatt
    56341 aggagcaagt cttgccggtt ttatgaaaaa agaaaagcgg acgtttttgg ctgtcttttc
    56401 tcaatcactg aatgatgaaa actatgcggt gaactactta aagttttcaa ctgacccttc
    56461 ctggaataaa agaaaggctt tatatgtcaa ttggttctca atgactgcat gggccggtag
    56521 caatatgatc ggtaattttt tcggctcggt gattcgagta gatgctgacc ttgtccattt
    56581 tgctttgacg gccatgttca ttttcatgtt tatcatgcag atgaaaagcg cactactgat
    56641 ctttacaggt ttattctcag gcgtattagg ggtcgtattc atggtattat tccaaaatac
    56701 tttcggattg attgcagcaa cagtcattgc ttcatttgcc ggatttatgc tggagaaggc
    56761 attcaaaaaa gaaaaagcta agaaactaag agaccgcggt aaagatgtca atgagccgct
    56821 cttcaacttc ccggaacagg aggccaatca ccatgactaa actatatttg ctacttttag
    56881 ttgcttgtct gttcatcgtg gcatatatcc cgcgcttgtt cccgatgctt tattttactc
    56941 atcgaaaagt gccatcctgg ttcagtgact ggatgaaata tgtaccggtg gcattatttg
    57001 cggcgttagc ttttaaagat gttttcatta ctcatgaaca tctggatatt gcttggaata
    57061 tcaaaatagc tgcaatgatt ctagtagcag gcgtggctta caaaacacgt tcgatggcgt
    57121 tgtcagtttt gacaggactt gcgtctgtct ttttgctgtc tatgctttaa actgttttat
    57181 tttattaaaa acagagattg cgacataagt tgttcaaact gatctatccg aactgcattt
    57241 gcaacagtca attctggatg caagtttatt cgtagggata aaaaagatta gtgttggctt
    57301 atgatgcaag ctctttttta ttttaggaat tagagaggga tttgtccttc tatgattttt
    57361 tgctataata gggaagatgt ttattttatg aaagaatagt tgagggaatt taaatgaata
    57421 aaaaattgat gcaaggaaca ttttggctaa cctttgctaa tcttctatgt aaagttttag
    57481 gggtagtcta tttgattccc tggctaagta tgatggggaa caatcaagat ggtatgcttg
    57541 ctacgacatt gtataatgtt ggctatcttc cttatggatt gttcctgatg cttggtacag
    57601 tcggatttcc aaatgcgatt gcaaaaaaag tagctgtagc cacaaaagaa ggagataacg
    57661 ctgcttgtcg gctgattttt agaagtacga tcaatatcat gtttgtcatc ggtatcgcct
    57721 ctgctgcact gatgtattta tttgctcctt tactagccgg aatcagtccg attgctaacg
    57781 ttaataatgg gatactagct atcagaagtt tatgcccatc tttgattgct atcccaattc
    57841 ttagtgcaat gagaggatat ttccaaggaa aaaatgatct gcggccttat ggaacttctt
    57901 tgattatcga acaggctgtg cgagtgatcg ttatcttggc tggtacttat tacttgcgcg
    57961 tattgactga cggaaccata ttagaagctg tattgatcag tacagtcgct tctttcttcg
    58021 gtgggttagc tgcgattatc catatgtata tcgtcggacg cagaaaagac ttcttcgaac
    58081 ttaaagattt tttgatttcc agccgttatt tcgaaagaga aaaccgatct gcctctgtct
    58141 ctatcattcg ggaaacacta ccgtttattt ttgtcggctc agtcattact atcgttcaaa
    58201 tgatcgacca agtaacgatg aaaccactgc ttcacttttt ccgtccagag atcgcagatc
    58261 agcaactgga attcttattc agccgtgctt ctgtcaatcc aaataaattg acattgatcc
    58321 tgatctccat ggtaggaaca gtagctataa gcagcttgcc aatattaagc acgatgaaga
    58381 aaaaagatcg gatacaaatc gaaaaaacag taggagatag tttttcgatt gcgttattga
    58441 ttcttcttcc ttcattgact ggaatgtctt tattagctgg accactatac acattgtttt
    58501 ttggctatga tcctgaaagt gtcggatatt tccaaatggc tttgctagct tctttgtttt
    58561 tctctttatt cacgatccta tctacgatgc ttcaatcttt gaatcaccat cgttttgcga
    58621 tccgattaac tgtagaagca attatcctga aagtcatctt ccaagtaatc ggattaggat
    58681 tagttggcgg atacgggatg agcttatcaa atggcttagc attcggtatt gtctttgttc
    58741 gcggctatca ctttatgtgc aaagaatacc gaatagcacc tttagcaaag atcagcaatt
    58801 ttttcttaaa aactttccgc tccaccctga ttatgcttgc agtatgtttt gccgttttct
    58861 ttttgctgaa tcagcgattg tcaatggaat caaaaagcta tgcaatgatt tattgtgtgg
    58921 ctgtaggaag tattggcggc ttagtatttt tattttctca attcggaaaa aatgggtttc
    58981 gaatgttgaa aaatgttaaa catcatagca gaagcaaaga ataggttaac taatcgtttt
    59041 ttgctgtcac ttgaaaaacg gcaactcgta tgattacgct tgtcgttttt ctattttcca
    59101 attttagttt catatctaat cttacttatg atatagttat aaggtctgga aaaattcttt
    59161 gaaacgagga aattaaacac atgaaacttg cagtagttac agatagttcg gcatatctgc
    59221 cggaacgtat caagaaccat cccgacttat tcgttattcc aatccctttg attatggatg
    59281 ggaaaattta taacgaagga atcgatatcg aagcggatga atattatgga cttttaaaaa
    59341 acagtaaaga ttttcctact acttcacaac ctgtcgtagg ggaagttttg ggtttatatg
    59401 aggaattgaa agagaaaggg tatgacacga ttttaagtat ccatctttct tcagggattt
    59461 ctggctttgt caacacatta tttgcgatga aagatgacat cagcggagta acggtcattc
    59521 cttatgactc taagatcact agtatgccga tgggacacat ggtagaagct gccttagact
    59581 taaatgatga aggtcagtcc cttgatgaaa tacttgcaca tatcgatcga atccgagata
    59641 atacctacgc ttatctgatt gtagatgatt tgaacaattt agtacgagga ggacgtttga
    59701 caaatggtgc agcgctgatt ggcagcttat taaaaatcaa accgatcctg acattttctg
    59761 aagggaaaat tgttttattc gaaaaaatcc gttcaagtaa aaaagcattt gctcgagctg
    59821 aagaaattat tggtagaaga aataacgaaa tacaaccgcc agtcaaactt tacgtgatac
    59881 atgcaaataa tttagaagta gcgattgcgg agaaagagaa attgcagaaa aaatatccaa
    59941 atgcagaaat cgaaattggt catttcggac cagtcattgg tacacattta ggtgaaaaag
    60001 ccatcggcat tgccatttca gcgcaataat tccttttatt caaaaaacat accaaaaata
    60061 ttccaacatc atcttggact ttctacatgt tactaatgag cgtgtaaaag aacgagatgg
    60121 tgtttttatt tctatcaatg aagctctttt tctttgcaat cctcacttca atcctctata
    60181 atgtcgcata tagtttagta aatgagtaaa ctactaattt acttatttac taaaaataaa
    60241 aggatgagga gttaaaataa tggaaatacc aacaaattta aaacataaac cagtaatcgt
    60301 tgtagaagac tatgataaag ttgatggaag aaatgcatta aatacggatg caaaagggct
    60361 ttcactgggc cttgctcagt ggaatgatcg tggaaaagtc gatatctcag gcaaggtatg
    60421 gcgacatact ggagaaaaat ggtcacgaca gtcggaagaa ttaccaatca cacgtatttt
    60481 agatttagcg atcttagctg cacaaggaag tttatacttc caagatgctt atcgttatga
    60541 aaaattttat gatccagaaa atccagtcgt agacatcatt ggattacaag ggaaccgaat
    60601 gacggtagaa gtagatacca aaaatccaaa gatcgatgaa gacatcattt tgtattacga
    60661 tacactacaa aaagacggag aactgattgg ggaacgattc cgtattttaa aacgtctttt
    60721 agatgagcta ggatattaat agacagagat gatcaaaagg ggaagagaag catggagaat
    60781 ttctcactaa cagaaaaccg aaccttttca cggctagaaa agcaaatgat ctggaagaaa
    60841 ccgaaaagcc atcggacaag tgcagaagaa tggcggatcg cctccgaaat caaagggaat
    60901 tggcaagatc ctgaaatgaa aatcagtaac gtacttttgg aaggagatgc cgggtcgggg
    60961 aagacacaat tagccaaagc actatctgct gatctgcaac ttccctatac aaaagtgacc
    61021 tgttttgcag atatggacaa atcagatgtt ttcggagcct tattacctgt agtagattct
    61081 aataaggaac aagaccaaga attactagaa gctatttacc aaacagatac acttgaagct
    61141 gtactgacac tgatccagaa ccattacggc attgatcctt tttctgctaa agaaaaatta
    61201 gcagagctag ttcaaaggat cgaagctgat tatccagatg caatccatta cagctattac
    61261 ccttctgaaa tcgttcgagc gattgaaaaa ggatatttat tagagattca agagccgact
    61321 gtcatccgag atgcctctgt tcttgtggca cttaactcag cgctcgaacc aaatgggatg
    61381 ttgaatttac cgacaggaat cattcgtcgc catccagatt gcgtcattgt gatcactaca
    61441 aatcgaaatt accaaggaaa tcgcccatta aatgaatctt taagagatcg gatgcaacat
    61501 gcggaaaaaa tggatcttcc tgccttagaa gtcatggcag aacgtgcgat ggcgaaaact
    61561 atgatccaaa aacaagaact tctcttaaag atggcagaga ttatccgttt gttggatgaa
    61621 actgcaaaag ctaacgccat caaaggtgta gcaggaatgc gttcttattt ttattgggca
    61681 aatacctata agcaaggaca agatttactc cagtcgattt atccaaaagt tttgtataaa
    61741 ttatccactg attcagatga attggcaatt cttgaacaag ctttgtctga cagtggattg
    61801 ctactggaac ttcaggacat attgagaaaa gaaaaatggg gtcatcctca atctgagcat
    61861 acaaaaggaa gaaccattag cgccgaagaa gcaaatgaac gaaacatcac tgaaaatgct
    61921 gaagaaattc tgcgcttaga tgaaaagaaa tcgttgtctg ctgaagaacc aaatgaggga
    61981 gaagagaaac aagaagaaac aatagaaaaa aacgagattc ctcctcaaat gcaaaaagaa
    62041 cgcagtagcg atatcgaagg aaaaaatcaa aaagaacaac aaacaggaga tgattctcaa
    62101 gaaatgtctg cttctgacat ggaagcacat gataaggaaa tcaagaagca actgaataaa
    62161 gaagcgcgac aaatcatgaa ggaaacgatt catgaaaaag aaggtctcat cgttcaccga
    62221 ccagctttcc aaggaaaaac gccggaagca cgtgagctac acatgcaagt aatgccaata
    62281 gtagaatcac ttagccggca aattttagag ttactggata atgaacaaac agagacgtac
    62341 caaaaaggaa aatacgaagg tcagcggttc aatgcaagca aagtagcata tggtgatttg
    62401 agaaattttg acaaaaagaa cccgccacat gagcaacctt ctttagcggt agctgtacgg
    62461 atcgatgaat ctgggtcaat gatacgggat gatcggatcg aagcggcaaa aaaagcagcg
    62521 attgccattg ccgaattttc taagaaagtc gatatcccat tgttgattta cggagataca
    62581 gcagaccgtt cgtcaagaga aaagacttct ttgttttctt ataaagaatt tgaagacgga
    62641 tttcaatggt taaatgaaaa attagtcact atgaaaccaa ggcaaaacaa tcgtgatggt
    62701 gctgcacttc gtttagcagc agaaaaatta aacagacaat ccgcaacaac caaactgttg
    62761 cttaatatta gtgacggtca gccaaaagcg ttgccggatt atacaggcaa aaaagcaaaa
    62821 gaagatatcc agtctgtttt gaaagaatat gaacgtcaag gaatcctatt tgtctccgca
    62881 gctattggcc aagacaaaga agaaatcaag tcgatctacg gtgaaagtcg ttttgtagat
    62941 attactgact tgaatgaatt tcccaagcaa atgattcaac tgattgcccg ctatctatga
    63001 taaaataaag ctcaacgaac gcacttagca gattcgttga gcttttcgtt tctagttacc
    63061 ggtaacaagg atacttctaa aatagaatcg gttataatca agagggaccg ttaaaggagt
    63121 gaaacgatat gatacaagaa caaaaatggt ggaaagaagc agtaggctat caaatctatc
    63181 ctgctagttt caaagatagc aatggcgatg gtcaaggaga catcaatggg atccgtgaaa
    63241 aacttaatta tttgaaagat cttggtatcg gctttatctg gatcaatccg atctatcaat
    63301 ctccatttgt cgataatggt tatgacgtaa gtgactatca agatatagaa gagagattcg
    63361 gaacgatgga agattttgat ttattgctaa aagaagcaca tgaattaggg atcaaagtga
    63421 ttatggatct tgtcatcaac catagttcgg atcagcatca atggtttgaa gaatcgaaaa
    63481 aatctaaaga aagcccgtat cgcgattatt acatttgggt cgacggggta gatggcaaag
    63541 aaccgaataa ttggacatcg attttcggcg gttctgcttg ggagtattct catgaaactg
    63601 gacagtatta tctgcatgtt tttgcaaaag aacaaccaga cttaaattgg gaaagcgaga
    63661 aattgaaaga agaactattc aatatgatcc gatggtggtt ggataaaggg atagatggat
    63721 ttcgtttaga tgcgatttct catgtaaaaa aagatgaata ttcagtaaaa gccacagaga
    63781 accctttctc accctttcaa aatgtctcag gaatcgaaga acatttgacc gatttgaaac
    63841 atgtttttga agagtacgat atcatgactg tcggagaagc aagtggtgtc actgcagaag
    63901 aaggaccaca atgggtaggg aaagacggtt atttcgatat gatattcgaa tttgatcata
    63961 tccatatctg gcagcaagaa aaagaagggc aattagatgt ccttaaattg aaacttgcat
    64021 taagcgcttg gcaaacttca ttggatggta tcggatggaa cgctttatat atggaaaacc
    64081 atgatgttcc tcgtgccgtt tcagtgtttg gagatactcg tcccgatttt tgggctatgt
    64141 ctgcaaaagc aatcgctatg atgtatttct ttttgcaagg tacgccattt atttatcaag
    64201 gacaggaaat cggaatgacg aatatgccct ttgaatcgat cgatcaagtt gatgcagtag
    64261 attcgaaaag actttataaa aggctgcttg cggaaggtaa gacaagagaa gaagcattgg
    64321 atatcattcg tgaaacaacg agagacaaca gcaggacacc catgcaatgg acttcggaac
    64381 aatatgctgg tttttctaca catgaacctt ggctgatcac taatccaaat accaaaacga
    64441 tcaatgtaga acaacaagaa tatgaaccag agtcggtcct gcaattctat aagaacatga
    64501 tccgcattag acaaaccaat aaaggtctga tatacggttc ttataaagaa tatcttcatg
    64561 aacatccaca actttatgtc tatgaaagat atttagaaga tgaacaatat cttattatgg
    64621 taaacttaac agaatcactt gctgactatg aacttccaaa agaagcagat cagtcctgga
    64681 cattactctt gtcaaattcc tctagcggag aatttgaagc taaaggcata ctagcacctt
    64741 atgaagctcg gttatataaa acaaacaagt aaaacttcct cgttaaagtt cattagttgg
    64801 actttgcgag gaagtttttc agattgctct gtcaattact catttcaata attcgctcta
    64861 ggaccaccga tatatttagg acgagagcga agggctgtca cgtgagcttg tccaagggtt
    64921 ttcaaacgag gtctgacagg tacttggaca tgtttgatat gcataccgat tgatgtgtca
    64981 ccgatatcga taccggcttg tccaactacg tgttccactt cgacaggatc attgaactgg
    65041 tcaaaagcag caacagaaca agcacctcca gcatgtagtg caggaacaac agagacaatt
    65101 tcgaaatttt ttgcttctgc cactgttcgt tctactacta atgctcggtt caaatgttca
    65161 caaccttgga cagctagcgc aatttcttta ggatccaaca actcttttaa cgtacggatg
    65221 atccattgac caacttccgc actggaattt tttccaatat gtcctccaac gacttcgctt
    65281 gtgctgcatc ctaaaacaaa aagatcacct tttttcaagt gtgcctcagc caatatgtca
    65341 ttaactattt cagtcaattg gtcttttaat tctttttctg acaacttcat tttctaaaac
    65401 cttctttttc aattaatatt gcttccgtgc ttgaatacgt tgaagacttg cagttatagg
    65461 aaaggcaagt cccattccaa tcagattttg gaagatgttt cctggtatag aagccactcc
    65521 agccggccaa tcatataaaa tccaaccggc gataccatag ccgatgatca taactaagct
    65581 tcctaataaa agccctaatc cccacatacg agtagaagat ttgctgaaag aaccagcaac
    65641 atatccttgt aacccgtgga tcactaatga aaaaactgcc cactgcggat atcctgaaat
    65701 caaatcgatc aatagaccac tggaagcacc aacaactaat ccacccgttg gaccataaag
    65761 aaaagcagcg gtatagatcc cggcctcgca taatgtcaca aatccattcg tagccggtac
    65821 agggatcaaa attgttaatg aaagggcaac tgtcaacgca atcagcatag catagatcgt
    65881 taattgctta gttttcattt ctcattcctc ctttttgaat accgccagac cagacacttc
    65941 cggtatgatc gttcatcagc acgccattag aaatacaatg ggcaacaaat tttttacttt
    66001 ctgctactgc tttggtaaaa tctgccccta acacaagatt cgctgttatt gcagaagaaa
    66061 aggcacaacc ggccccgttt actgttgtag tgtcgatttt tttatgagaa aatacctcat
    66121 aatgatcaat tgaatagaga agatccacag cttcatctcc agccatcctt gtgccgcctt
    66181 tgatcacaat gttttttgtt cctgaagcag tgagttcttt agcgagatgg atcatttctg
    66241 ttaacgaaga gggaagagct tgaccagaaa gtaaagcagc ttctgccaaa ttaggcgtaa
    66301 tcatcgtaac aagtggaaaa agttcttcga tgagctgcga aatatacaat tgattgatca
    66361 cagcttcagt ttctttgaat gccaaaacag ggtctaaaat gattgggata ttttgttttg
    66421 tttttatgaa gtctcgaaca accatgattg cttcacttga attcaataac ccaattttga
    66481 taccatctaa tgaagtcatt ttatcaatcg aaactaactg tcgtttaagc aattccaaag
    66541 atatagattc cagcataaat cgctcattaa tatctagtgc ccctatagaa gtcaaggcgc
    66601 ttagtccgaa tagaccaaaa ttctcaaaag tttttaaatc tgtttggatt cctccaccag
    66661 caaatggatc agaaccgcca attgtcaaga ttcttttcat aacattttcc tccatgaata
    66721 agagtataac gaaattttca aaaaagaaaa acagccaatt ggcatatttt catctcatcc
    66781 aatttaaaaa aacaaaaaga aaagaaagac caaaatggat ctttctttcc ttaaatagtt
    66841 aggacttttg tgattttaat tctttctcga tttgaagccg ttgcactttc attgtagctg
    66901 ttcgcgggat tgcatcaaaa tcacggatga tagggacgtt caagcgagga agttcatgga
    66961 cttgctccca ccatcgattc caatccattt ctttatcagg agctaaagca ataatcggtt
    67021 gtggagaatg atttttatcc cttacaatca ctacttctgc caaaaaatct aacgaatcta
    67081 ataaaaagtc ttcaatagct aatgtactat tgatcgtttc gatcaaatcc acttgccgat
    67141 ctttcaaaaa taggtggcca tgcttatcca taaaaccgta atctccgcta tcccaccaat
    67201 cgccataaac attttcctgg aaccgtgcat cttccttgta ataagtcaaa gcccgtcctt
    67261 tagacagtaa ttgtatatga ccatctgtgt tttcaggtag gacattccca actgaatctg
    67321 taatccgagc gcttgtcatg tcttccagtc caacgcccat atctcttgca tcacttgttt
    67381 tcaaactctc tagtgtatga gccttaagaa tcattggtcc gcattcactt tggccatata
    67441 cttgaagaaa taccgcatcc tgtgccatcg acgttcgcaa aaatgtcttc attgtctggt
    67501 tgtttatagc atcaaaagtg gagtgatagt atcggatacc cgaaaaagct tctggatgct
    67561 ccttagcagt aaaacgccac tgaacaaagt tattcggatg ggtctctagt gcaattggcc
    67621 ggtgagcttc caacatatga acaacttttg aactttgtgc gtttgctaaa ggcatcatag
    67681 gaaatcccat ggacatcaaa gaagagatac caatattgaa tctggaatgc actggagaga
    67741 tgtgaaaagc gattaatttc ttttccgaaa tttttgtgaa aactgttttt tgccatttcg
    67801 tccgccatcc catagaatga gcagaatgac aaataagttt agggatacca gttgtaccag
    67861 aagtatgggt catataagaa atttcatttt tgtctaaaaa tgattgagaa acagacaaag
    67921 caggttgttc cattaaataa agaatagg
//
LOCUS       DAPBAF010000010        65662 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.010, whole genome shotgun sequence.
ACCESSION   DAPBAF010000010 DAPBAF010000000
VERSION     DAPBAF010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 65662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 65662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..65662
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.010"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            312..2456
                     /locus_tag="RD451_000756"
     CDS             312..2456
                     /locus_tag="RD451_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HDT7566041.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(2508..3548)
                     /locus_tag="RD451_000757"
     CDS             complement(2508..3548)
                     /locus_tag="RD451_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HDT7566042.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(3825..5627)
                     /locus_tag="RD451_000758"
     CDS             complement(3825..5627)
                     /locus_tag="RD451_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7566043.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            complement(5641..6393)
                     /locus_tag="RD451_000759"
     CDS             complement(5641..6393)
                     /locus_tag="RD451_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7566044.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            complement(6402..6764)
                     /locus_tag="RD451_000760"
     CDS             complement(6402..6764)
                     /locus_tag="RD451_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HDT7566045.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            complement(6940..7812)
                     /locus_tag="RD451_000761"
     CDS             complement(6940..7812)
                     /locus_tag="RD451_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HDT7566046.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            complement(7863..8351)
                     /locus_tag="RD451_000762"
     CDS             complement(7863..8351)
                     /locus_tag="RD451_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HDT7566047.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KN"
     gene            complement(8489..9280)
                     /locus_tag="RD451_000763"
     CDS             complement(8489..9280)
                     /locus_tag="RD451_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HDT7566048.1"
                     /translation="MLTGGLLAGATYTLGAQKSLTWDNGPRLIDMVTETKKIKDANKI
                     VIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKKSTGAIISLEDTSA
                     QITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSFNEFTGGTITAKDE
                     LGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSLHEMENSGYTIQTS
                     GESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD"
     gene            complement(9335..9943)
                     /locus_tag="RD451_000764"
     CDS             complement(9335..9943)
                     /locus_tag="RD451_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HDT7566049.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            complement(9936..10253)
                     /locus_tag="RD451_000765"
     CDS             complement(9936..10253)
                     /locus_tag="RD451_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HDT7566050.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            complement(10409..11137)
                     /locus_tag="RD451_000766"
     CDS             complement(10409..11137)
                     /locus_tag="RD451_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HDT7566051.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            11296..12177
                     /locus_tag="RD451_000767"
     CDS             11296..12177
                     /locus_tag="RD451_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDT7566052.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            complement(12414..13457)
                     /locus_tag="RD451_000768"
     CDS             complement(12414..13457)
                     /locus_tag="RD451_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDT7566053.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFFQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(13460..14128)
                     /locus_tag="RD451_000769"
     CDS             complement(13460..14128)
                     /locus_tag="RD451_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7566054.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERVGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            14270..16606
                     /locus_tag="RD451_000770"
     CDS             14270..16606
                     /locus_tag="RD451_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDT7566055.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            complement(16721..17032)
                     /locus_tag="RD451_000771"
     CDS             complement(16721..17032)
                     /locus_tag="RD451_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566056.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            17213..18688
                     /locus_tag="RD451_000772"
     CDS             17213..18688
                     /locus_tag="RD451_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HDT7566057.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            18735..19319
                     /locus_tag="RD451_000773"
     CDS             18735..19319
                     /locus_tag="RD451_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HDT7566058.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            19321..19740
                     /locus_tag="RD451_000774"
     CDS             19321..19740
                     /locus_tag="RD451_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HDT7566059.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIKEPVYYKDGEKPL"
     gene            complement(20021..20305)
                     /locus_tag="RD451_000775"
     CDS             complement(20021..20305)
                     /locus_tag="RD451_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HDT7566060.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(20657..21367)
                     /locus_tag="RD451_000776"
     CDS             complement(20657..21367)
                     /locus_tag="RD451_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HDT7566061.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            complement(21364..22836)
                     /locus_tag="RD451_000777"
     CDS             complement(21364..22836)
                     /locus_tag="RD451_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008269079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HDT7566062.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            22974..23447
                     /locus_tag="RD451_000778"
     CDS             22974..23447
                     /locus_tag="RD451_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDT7566063.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            complement(23600..24151)
                     /locus_tag="RD451_000779"
     CDS             complement(23600..24151)
                     /locus_tag="RD451_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HDT7566064.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            24256..24786
                     /locus_tag="RD451_000780"
     CDS             24256..24786
                     /locus_tag="RD451_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HDT7566065.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            complement(25269..25712)
                     /locus_tag="RD451_000781"
     CDS             complement(25269..25712)
                     /locus_tag="RD451_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7566066.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(25728..26888)
                     /locus_tag="RD451_000782"
     CDS             complement(25728..26888)
                     /locus_tag="RD451_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HDT7566067.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            27395..29095
                     /locus_tag="RD451_000783"
     CDS             27395..29095
                     /locus_tag="RD451_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566068.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            complement(29197..30030)
                     /locus_tag="RD451_000784"
     CDS             complement(29197..30030)
                     /locus_tag="RD451_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HDT7566069.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(30334..32499)
                     /locus_tag="RD451_000785"
     CDS             complement(30334..32499)
                     /locus_tag="RD451_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDT7566070.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEKKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            32759..35053
                     /locus_tag="RD451_000786"
     CDS             32759..35053
                     /locus_tag="RD451_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HDT7566071.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            35046..35711
                     /gene="pgmB"
                     /locus_tag="RD451_000787"
     CDS             35046..35711
                     /gene="pgmB"
                     /locus_tag="RD451_000787"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HDT7566072.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            35704..36711
                     /locus_tag="RD451_000788"
     CDS             35704..36711
                     /locus_tag="RD451_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HDT7566073.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KGGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            36733..37752
                     /locus_tag="RD451_000789"
     CDS             36733..37752
                     /locus_tag="RD451_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDT7566074.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(38033..39404)
                     /gene="nhaC"
                     /locus_tag="RD451_000790"
                     /pseudo
     CDS             complement(38033..39404)
                     /gene="nhaC"
                     /locus_tag="RD451_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
     gene            complement(39513..40934)
                     /locus_tag="RD451_000791"
     CDS             complement(39513..40934)
                     /locus_tag="RD451_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDT7566075.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(41177..43054)
                     /gene="tdc"
                     /locus_tag="RD451_000792"
     CDS             complement(41177..43054)
                     /gene="tdc"
                     /locus_tag="RD451_000792"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HDT7566076.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(43345..44601)
                     /locus_tag="RD451_000793"
     CDS             complement(43345..44601)
                     /locus_tag="RD451_000793"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HDT7566077.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     misc_binding    complement(44713..44918)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            45181..46482
                     /locus_tag="RD451_000794"
     CDS             45181..46482
                     /locus_tag="RD451_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDT7566078.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(46551..47150)
                     /locus_tag="RD451_000795"
     CDS             complement(46551..47150)
                     /locus_tag="RD451_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDT7566079.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
     gene            47404..48285
                     /locus_tag="RD451_000796"
     CDS             47404..48285
                     /locus_tag="RD451_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7566080.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            48298..49908
                     /locus_tag="RD451_000797"
     CDS             48298..49908
                     /locus_tag="RD451_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HDT7566081.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(49985..50644)
                     /locus_tag="RD451_000798"
     CDS             complement(49985..50644)
                     /locus_tag="RD451_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HDT7566082.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(50927..51592)
                     /locus_tag="RD451_000799"
     CDS             complement(50927..51592)
                     /locus_tag="RD451_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate 1-dehydrogenase family
                     protein"
                     /protein_id="HDT7566083.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
     gene            complement(51739..52344)
                     /gene="dhaL"
                     /locus_tag="RD451_000800"
     CDS             complement(51739..52344)
                     /gene="dhaL"
                     /locus_tag="RD451_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
                     /protein_id="HDT7566084.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(52372..53382)
                     /gene="dhaK"
                     /locus_tag="RD451_000801"
     CDS             complement(52372..53382)
                     /gene="dhaK"
                     /locus_tag="RD451_000801"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HDT7566085.1"
                     /translation="MPERKDGNKLKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRV
                     VAKNQKAEQVGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEAD
                     SGKGVLLIVKNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAG
                     TVLVHKIVGDAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDE
                     IEYGVGIHGEPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQ
                     FVFMNDVLALLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTI
                     SW"
     gene            complement(53357..53803)
                     /gene="dhaM"
                     /locus_tag="RD451_000802"
     CDS             complement(53357..53803)
                     /gene="dhaM"
                     /locus_tag="RD451_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HDT7566086.1"
                     /translation="MKAKPIVSNYVKERKILVKKSILLISHSQKVTDGIKEMIEQMQK
                     SEEVQIFSLGGINGEIGSDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEE
                     EQQQRYHLVDAPLVEGAFAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            53906..54226
                     /locus_tag="RD451_000803"
     CDS             53906..54226
                     /locus_tag="RD451_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HDT7566087.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            complement(54338..55207)
                     /locus_tag="RD451_000804"
     CDS             complement(54338..55207)
                     /locus_tag="RD451_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HDT7566088.1"
                     /translation="MGKVMKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTI
                     SSSGAENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELE
                     EALEAAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQ
                     QAKEFNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAAS
                     FQRIKDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGV
                     LVAAAYGIIRKKK"
     gene            complement(55303..56607)
                     /locus_tag="RD451_000805"
     CDS             complement(55303..56607)
                     /locus_tag="RD451_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDT7566089.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVWFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEYTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            complement(56604..57113)
                     /locus_tag="RD451_000806"
     CDS             complement(56604..57113)
                     /locus_tag="RD451_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566090.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            complement(57288..59423)
                     /locus_tag="RD451_000807"
     CDS             complement(57288..59423)
                     /locus_tag="RD451_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDT7566091.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(59506..61161)
                     /locus_tag="RD451_000808"
     CDS             complement(59506..61161)
                     /locus_tag="RD451_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDT7566092.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(61163..61477)
                     /locus_tag="RD451_000809"
     CDS             complement(61163..61477)
                     /locus_tag="RD451_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HDT7566093.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            61647..61907
                     /locus_tag="RD451_000810"
     CDS             61647..61907
                     /locus_tag="RD451_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HDT7566094.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            61921..62235
                     /locus_tag="RD451_000811"
     CDS             61921..62235
                     /locus_tag="RD451_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HDT7566095.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(62965..63519)
                     /locus_tag="RD451_000812"
     CDS             complement(62965..63519)
                     /locus_tag="RD451_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HDT7566096.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(63645..65574)
                     /locus_tag="RD451_000813"
                     /pseudo
     CDS             complement(63645..65574)
                     /locus_tag="RD451_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
BASE COUNT        19575 a        13565 c        11707 g        20815 t
ORIGIN      
        1 tctttttctt tttaggatca ttatttttat aaatttttgt gatactttcc aaactttggt
       61 ataatttaca tatgcataac catttttatc cccacttgtt tatccccaaa caaaggtggt
      121 ctatgcaata aaatgaacgt caaagaaaaa cgaatgaatg ctcgttgctt atttacaaat
      181 tgttttattt agaatacaca gacagattta tgaaaagaaa aagcttttcg acacgattat
      241 ctgttccaaa aaatgtctaa tgaatgctga ataagacaga aaatcaatga aaggaaaagg
      301 actagtttat tatgaaaaat aaaaaaacga tacgtttgct agctgctact tggctgattg
      361 ctccgtctgt tttgtcgacc aataccgtat ttgccgtaga taatcaaata gctgatcaaa
      421 cagtcacaac agatacgact acatccagct cagctactag tgaaacaacg gattctttta
      481 cagaagaccc aactggaaca actaactcaa caacaggatc gaccgagcca actgaaattg
      541 atccggctga tccatcagaa aatgaaaagc cagccgagac atattccctt acaattgctc
      601 cttctttgat tggtaagatc caactgactg cttcgacagc ggattcccct gaacagcaac
      661 ctttggatat tacggaaagt ggaacggtag aaggtttatt agcggaaacg aaggtaactt
      721 acactattac gccagctgaa ggtgaacaaa ttgcttcagt cgctgttaat ggtgccaaag
      781 aagtaaatta tgatgcaaag acctttacag taggtacgaa caatttatct attactgcag
      841 aatttaaagc tggaccggat acttcaacag agaaaccaac tgatcctagt gaagaagtcc
      901 ctagtacacc agatccggaa acgccaaaca aaccagatgt gggtaataac aacaataata
      961 atggttcaaa taattcaaac aataataaca ataattcgaa cagcgggaat tcttcgaatc
     1021 aaacaaaccc atctggatcg aataacaatg gaaatactca gagagaacca aaccatccaa
     1081 acaatggttc atcgaatggc ggaacgaaca atgcttcatc tcgtccaaat acagcaaatc
     1141 aaagcggtat agagaatcca tcttctgctt cttctgattt tgttgtaaaa tcaccaattg
     1201 atgctgtatt gcctacaaat acaacgaatg tccaacaagc aatcgttcga gaagcattca
     1261 agcatcttgg aaaaccatat gtatggggag caaaaggtcc aaatactttt gactgttctg
     1321 gtttgactta ttacgtatat atgaaagcaa ccggtcatta tatcggtggc tggacaggcg
     1381 aacagcaata tgcaggtacg cagattccag taagtcaggc ccaacctggc gacctcgtct
     1441 tctggggacc ttcttccggt gttactcacc atgtaggtat ctatattggg aacggacaat
     1501 ttatccatgc gcctcaacca ggagataaag ttcgagtaac ttctatttca gatttcacgc
     1561 ctgattttgc tgtccgagta aacttagcag gtttacctgc tgcttcaggt tcgctgacag
     1621 gcggctcatc tattttagat ggattagatg gctcgttcca tttcagtcaa aaccaaacaa
     1681 ctgatcagtt cttgaaaaag attgcagatg atgcacagga aatcgggcaa aaagaaggaa
     1741 tctacgcatc agtcatgatg gctcaagcta tccttgaaag tggatctgga aacagcttat
     1801 tatcaagcga accaaatcat aacctttttg gtatcaaagg atcatataaa ggaagcagcg
     1861 tgaccttcaa tacacttgaa caagatagtt ccggacaaag ctaccaaatc cgcgcacaat
     1921 tccgtaaata tccttcttac aaggaaagtt tggaagacta tgccgacttg atcaaaaatg
     1981 gactgactgg caatcctgat ttctacaaac caacttggaa gtcggaaaca aaagactaca
     2041 aagaagcaac caaatatttg gaaggacgtt atgctacaga tcgccaatat tcacaaaaat
     2101 tgaacgcgat catcgaagcg tacgacctga caaaatatga tgaaccgaaa aaagaagcag
     2161 caacaactga agaagcaaac gctgaaatcc tcaatatgtc taagcgattc gatgtgccaa
     2221 tcaaatggac aacagatggc gtgccaatca caggattaga attttcaacg ataaaacgcg
     2281 tcaacaacgc ttcttccatc ttccgtgtcg cttcaatctg ggatttgtgg aacaatttta
     2341 cggcaagaca gataccagaa acaactactc gtacagttaa agctgcaact gttcctgtac
     2401 taaccttgtt aagtttagac aaatcattct ggcttgatct gcctttaaag aaatagaata
     2461 aattaaaaag gggatgtgac actgtcacac tcccttttta atttattcta tttctttata
     2521 tttattttgt attccgttac aaactcgcgt acttggttag gttccagagt gacatctcca
     2581 aaactttcaa gtcgctccgc tcctggcagt tcttgagtct caaatgtgat accgccatga
     2641 tttactaatt tattcccgcg catttccggt ccatcttctc caaaatttgc tgtaaaaatc
     2701 acgattcctg aagcatctgt ttttacttgg atcgatactt tttcatctgg gcttgtcaat
     2761 tccgcagcat ttagtaaacc agattgtttt ttcaacaaaa atggatgatc gatgccgccc
     2821 actatcattg attggcgaaa atcactggca aagacctcac ctaatttttt aggacgttgg
     2881 aagtcaaatg ctgtgccact tactgaaact acttctcctg taggcgttgt atctttattg
     2941 agcgtagcaa ataatcggct attcaaccaa agtatatgtt cgtcgattga ctgtgctgga
     3001 tcaccggtta aattgaaata gacatgattt gtaggattga atactgtttt gcggtcactg
     3061 atcccttgga ccgtcactcg ccatgtatca tcgttcgtca gcgtataccg tacttctaca
     3121 tctaaagttc caggaaatcc gttttccata tctgggctag tctgatagaa aatgaccgat
     3181 gcttcgtttt caccattgat gactgtataa tgccactgct tggcttcaaa gctaggtgca
     3241 ccaccatgta aacaatgacc agtgtccggg tctgttttta cttcgaacgt ttcatcatct
     3301 aatttgaatg tgccattcgt aatccgtcca gccatacgtc cgattgaagc accgatataa
     3361 gggtcttttt ctagatattc ttttgcttca tcaaaaccta agatcaactc tcgtttttca
     3421 ttatcgatta ttgtttgaaa atgaacaacc cgtgccccaa gatcactgac agacaaagat
     3481 gtcccatttt gattcgtgat cgtaatcaag tgatagtttt cgccaaaatt ttgttcattg
     3541 atttccatgt tccttgcacc ctcttttctt tcatttgcac tgattccagt atacatggaa
     3601 accgttttct taacagctta ttccgtgagt aacgagaaaa aatttactat attctaataa
     3661 aagaccgtga aaaaaaggtt gtgacaaaaa tattgtcaca acctcttttt ccgaacaaac
     3721 ggtgttcaaa agcttgcatc tgcggtaata agcccaacca aacgaaaaat atgaggagct
     3781 atttttgctt ggctgttctt attacttgat gcaggacagc tttttcacaa tctctttttc
     3841 aatacgattc cagtatataa ccatgtcgtc agtacatagt agatgaaata caatacgaag
     3901 aatatcgtaa acggaaccca aatatctttg tatggatttt gcatgaatag accaaacatt
     3961 tgtaatccga ataagacatg gactacacct aagattcctg gtgctaagaa taacacgcct
     4021 acttctctac ggatcgattg tttaagcaac ccgcgtcgtg ttcctatctt ttcaagcatt
     4081 tcataacgag caatgtcact cttgcttcct gacaagatct tgaacatcaa acagctagca
     4141 agcatggtca agaaagctaa acctaggaag aatcccataa attcaaaacc agagaataga
     4201 ccattataca cttcatacat ttcatatttc tggttgctgt actctacttt ttgcaaagat
     4261 ggattgttca ttttattttg agcaacaagt gtttcgattg gtttcaggtt tgcttggaag
     4321 tcttttacct gaactagctg taaagtggat tgtggcaagt tcagttgatc aaattctgat
     4381 tgactgacta ccttgatttc tttttcttgc tgttccggca attcatagct tcgaagttcc
     4441 tcttgtacag tcagttcatt cattttttta gcaggaactt tttctttcgt gatcttcggc
     4501 ggtgttccat cttcatgttt tatcatgatc aatggttgag ccgcaaattc acttgcatta
     4561 tagtaaatcg ttcccgcatc ttctttttga gtataagaag cagaaagtgt tggtgaaagt
     4621 tctttgattt tttgctgatc ttctgcccga ggattattca tcactagatc atatccagaa
     4681 ttgttttctg tcaagtctgc aatttcattt ttaaaaccta atcctaccgt caaagcgccc
     4741 agtgccaagg caaacagcat agcgaccatt gagagcattt gtgtatattc acgaatacga
     4801 aagtttaact gtgacaatgt gaaattgttc aattttttca atgaaatctg ttctgatttc
     4861 tttagtaatg ataaaaagaa aatgatcaca gaatggaaaa tgaaataagt tcctaatacg
     4921 atcgtaacta aggctacccc tataccaaag acttgatagg tccccacgtg tttcatcata
     4981 tagtaaccgc agcctagaaa agcaattccc agtactactt caaggaaaaa caagaattta
     5041 tgctgcttga ttcttgttgg tgtctgatcc gcacgaatca atgctaaaat cggttttttg
     5101 acaatcgaaa aagcattgac aacagcagct aataaaaaca aaacagcaaa aaacaaaaca
     5161 gtgatcaaca acccgtgaat actaaaaggt gtaaaatgcg aaatattgag atctaactga
     5221 tccactaata atcggtggac gatacttgtc aatcctacac cgacagctga acccactaaa
     5281 gtagctgcga tccctactaa gaatgtttca gaaaaaatca tctgtgcgat ttttctgcct
     5341 tttgctccca gcatcataaa cattgcatag tctttttgcc gcatcgtcat caaaaaggaa
     5401 tttgcatata aaatataaac gaatgtgatg atccctagta aaacagaacc gaatcggaaa
     5461 atgataactg tagccgcaac gatcgtatta cttttcaaaa aagcttcgtt gcttgccatt
     5521 gattcaaaca tgtaaaaaat agcagatgcc ataactaatc ctgagaataa caccaagtag
     5581 tctcttaaac ggctcttgat cccagtaagt gataatttcc aaagcatagt caatctcccc
     5641 ctactgttcc aagtttccaa gaatagatag tatttctcga tagaaggaat cacggctttg
     5701 atctccacgt ttcacttctt gatggatacc gccatccttg atgaataaaa tacgttggca
     5761 ataacttgca gaaaacggat catgcgtcac aagaagaatc gatacatgat cttttgtatt
     5821 caattcgtcc atcgtatcta aaagatcccg ggcacttttg gaatccagcg cacctgtagg
     5881 ctcatcccct aatagaatcg ttggttgtgt gatcaatgca cgtgcggcgg cgacccgttg
     5941 tttttgtcca ccggaaatct cagaaggata gctttccaaa atatgagaga tggataaacg
     6001 ttctgcaatt ttttggacac gttgcttgat ttcttttggt ctgacgcctt gtaaagaaag
     6061 aggaacagcg atattttctt gtgctgtcaa gctttctaat aaattgaaat cttggaaaat
     6121 aaagccaatc tcattcgcac gaaaatctgc tagttgattt ccttttaatg tggtcacatc
     6181 tttttgattg attcggatat gcccatctgt tggtttatct aatgtggata aaatattcaa
     6241 aagtgtcgac ttaccagaac cagaagcgcc catgatccca ataaattcgc ctttttctac
     6301 atcgaagctg atgccgctta atgcttgcgt ctttttctca ttgttttttc cgtatacttt
     6361 tgttacattc tgtacttcga ctattttgtt catttctttc cctacccttt aattagtttt
     6421 tccagtgctg ttttcggcac gtcttttttt tcgacttctt catacgaagt gacaccttta
     6481 tttttgttcc aggtgatttt taaatatgct cctttacgaa gcggtcgagt caattgtccc
     6541 ttgaagtcca gttctttttc cttaccctct ttcgtatagc caggcaggat atatctatag
     6601 ttgactgttt cttgtccaga gtctgatttt gaaactgttt ttgtaccatc tgtcgtaatt
     6661 tgtacatagt attcttctcc acccataact acgtaatctg cgattttcac ccctgcaagt
     6721 accacaacga tgaaaacaag tagaccgatc agaagttttt tcactttttc cccttctctc
     6781 ttactttata tactgattat agaaaaaagc gaacaattct gccttcgaat caactatcat
     6841 tcttctttca attttgtcat tttctttaaa acaactaaaa aaagagttca agacaataat
     6901 ccgtcctaaa ctccttcttc ctatcttaca aaaagtatgt cacttacggt ctttcatgtc
     6961 gcctgtattg ataacaggtt gcgttccttt gtctgtaatg attgagacaa gtaaattatt
     7021 gatcaattgg actttccgat catcggtgaa attgatttct tgtccatctt cgatttgctc
     7081 taaggccatt tgagtgattg tgacagctcc ttcaacaatg gtttgtcgag cagacaaaat
     7141 ggcttttgct tgttgacgtt ggagcatggc actagcgatt tctgttgcat aggctaaatg
     7201 gttcaagcgt gtttcgatta cttcgacacc tgctactgct aaacgctctt gcagctcttt
     7261 ttgcaactcg tcagacactg ccgtcgtgtt tcctcgaagc gtcaaatcat tctcattgaa
     7321 tgtatcatac gggtattggc tagcgatatg ccgaatggct gtctcacttt ggatttctac
     7381 aaaatcttga taatacgcta catcgaataa tgcctttgct gtatcaacga ctttaaagac
     7441 tactactgct gagatttcga tggggtttcc atccaaatca ttgactttta aaacagaact
     7501 attgaaattc cgaactttca acgaaacagt cattttttgt gccaaaggta tcgtaaggaa
     7561 aaagccattt tctcgaatcg tacctaaata ttgtccaaaa aacaaaatta cttttgcttg
     7621 attaggactg actacagttg ccgaacttaa caacaataac gtgatcaacc aaagaaaaat
     7681 acttaaaaaa agtgcccaaa ctttcgcttg ccacatacct aaatagaaga aaaacaatcc
     7741 aactaaagct aatacgacca atccgacaat ccctgcataa ccattgatat aaaatgctct
     7801 tttttctctc atgctacttc ctgcgctcct ttatccttca ataaatatct aatgttactt
     7861 ttttaatttt tttttcgaat acgcgccatt acaccttcta gttctaactc tttgtcttca
     7921 gtgatgtacc aaccgcttgc ctgtgtccct ccggctgcct gcggtaaata atccaatttt
     7981 gttcgaaccc agtgcttttc ttctgtaaaa tagtcttcta ccaagacctc tagatccatc
     8041 cctgctgaaa gaggcaaatc ttcccgaaca gatttaaaga taaatcgttc cttcttccca
     8101 tcatacttca atattcctgt atcgataatc ggtaaagaat aataatccag ctctttcttc
     8161 accgtcaata aatgtttgaa aacttcatgg tacacttgct ctaattggcg accttctgaa
     8221 ttgttcgggt aattaaccat cactttttct ttgtctggat catagaaggt ttggcttagt
     8281 tgagtgatat aagtatgtaa tctttccatt tctgttttta acttttctct ttgaccttct
     8341 tctaccttca tatactcttt caccctgttt tctttttaga tattttcttt cttattttac
     8401 tatagttatg tgcgttaagc gatgaaaaac agcaaagatt ggaaggatct ttgctgtttt
     8461 ttcttaaaat atccagttga gtacaggatc aatctgtttc attgtcctct tgatccgtcg
     8521 taatattgat cgatgtgtct ttagcagtga tctttagctt tttctgtcct tgttctaaca
     8581 aagtatttgt tattggctgg tagtcttttt caatataaga ttcaccagac gtttggatag
     8641 tatagccact gttttccatc tcatgcaaag ataaattgcc accgtttagg atgacttttc
     8701 cttctttgct gatcaaactg tcttctagat ggaagttgct gttttcacct gtgacgatca
     8761 agttatccac attggcctca tctaatcgaa gtgagcctaa ttcatctttc gcagttattg
     8821 ttcctcctgt aaattcattg aacgataccc agccatcatg tgtcttagta ttcacttttt
     8881 tgattgatac ttcgttgata tcaattgcac tattattccc ttcgattgtc aattcagata
     8941 attcatgatc tgcagggaca acaatagtga tttgtgcact tgtgtcttct aaactaatga
     9001 ttgcacctgt tgattttttg actgcattca cagtcaacac gccatttttc tcctttattt
     9061 ctggcttttc tgtcttatca taagtcgttt ttatctcaaa atccaatccg cgtatgaccg
     9121 aaactgtttg attttctgca tggatgacga ttttgtttgc atccttgatt ttttttgtct
     9181 cagtaaccat atcgatcaac cgaggaccat tatcccaagt cagactcttt tgagcgccta
     9241 atgtataagt tgcacctgct aggaggccac cagtaagcat cagaccaata ccggtaatca
     9301 aaaaatgttt caatctcaat ttatgtgtcc tccttcaaac gcccgctgaa tgcagatctc
     9361 tttttgtaat aaaacgtcgt cccatccatt taacaaagtt catcatgaca taaaaaagcc
     9421 cttttgttcc tttcagcaac agtggcgaaa taaatactgc gcttcctgtg gcgaacagac
     9481 cgacaccgat aaagaataat ccactcagaa tcgattgtcc aaacacactg attcctgaga
     9541 tgatcatgaa taggccaaca cctaagatac tgatacataa aacatagata ctaaaaatga
     9601 gcgctagtaa agcaaccaat agtcccccaa taaccaatat aaaccccagt gctagtggaa
     9661 tgaggacagg agaagcaaat aaaccgataa tgattaacca aatcaggcga atttgtcttt
     9721 ttggattttt cactaactcg ttttctgctt gttcttcttc tgaaaagtaa ctgattttta
     9781 attttaaggc aaactgcttt ggtgtaccat attcatcaat gatctgatct aatgtttttc
     9841 cagaatctaa aaaatattcc tcataatact ggatcaaatc aaaacgatcg tcttcaggaa
     9901 tttcttgaag atgatccaca acttcattca aatattcatt catttgtgct ctcctccaat
     9961 aaccggtcta aagaatctcg aaaaacaatc cattcatcaa taatttcttc taaatgacga
    10021 cttcccattg gtgtcaacga gtaatatcga cggtttctgc cttcaaaagg ttcatcatag
    10081 gtctcaagat atccttcttt tttcaatctt ctcaaaaccg gatatagtgt agattcactg
    10141 acagagagac tttcttgtac gatttttgtt aaggcatacc catacatatc ttccttgctt
    10201 aatgctgcta gcacagtacc atcaagaaga acagttggaa tctggatgtg cattacgtca
    10261 ccttctattc tcaagtgtaa tattttattt caatctatat tatacaacat ataatatagt
    10321 ttcaaaatca gtttgtcaaa tacaaaaaaa ctgactaaaa gatttgatcc tttttagtca
    10381 gcaaaaaatg gcttctcttt gatttttatt ataacagtgg cataatccaa tttgtccaca
    10441 tccagctcag tggcatgata acgatcattg caggtatcat gtcagctact gggaacattt
    10501 tcacgttgat cattctaaaa ccggtagcga ccatcaagaa tccgccgcaa gctttaaaat
    10561 ctaagatcat gtctggtgta gtcaatggat aaataaattt tgccaataag aacaaaatat
    10621 aaaaaataat gaattgggga attgctatca cagaaacgac ataccctaaa ttacacgcaa
    10681 aaatagctgc tgtgaaaaaa tcaaggacag atttagaaat caaaatcgta ctgtctcctg
    10741 tcatcccaga atctaaactt ccatagatcc ccgtaccact tgcacaaaat agaacaatga
    10801 ccgtcactaa tgtgctgata aattcatcgt gggtcatacc aagcttttca ctagggaaga
    10861 ttttagaaat aggtacttgc atcagcgcag cccccttatt tatcccatta cctaaatgaa
    10921 caatcaaacc aatcgctgtt cctatcacta aagcaaaaat aacagccggc atatttttca
    10981 tcggcgcaat ggaatagatt cccatcccca tcgaacacac accaaaaacc atcgtcagct
    11041 gtgctttaaa atgttcactt aatttatttc ctactaatcc gccaattagt ccgccaaaca
    11101 aaacggaacc tacattgatc aaaactccag ttggcatcaa aaaactcctc tctttttcta
    11161 cgaagcgaaa aaaatcagaa aaatttctgt aattattgct ttcgctgcaa gaaagattgt
    11221 aacagacaga gaagattaca ccaattcatt ttttgtgtta aagtattctt tattggaata
    11281 agtaggagga atatgatgga tatccataaa ttcgaagttt ttcttgattt agccgaaaca
    11341 atgaatttca ccaaaactgc tgatcgacaa ttcaccaccc aaggaaatat ttctaaacag
    11401 attctttcgt tagaaacaga attagacgtc aaattattcg aacgcgccca tagaaaaatc
    11461 gaattgaccg aagctggaag cttattgctc ccatatgtaa aaaatgtcgt agaacaatac
    11521 catgctatgc aagaagtgct tgaaacctat acgaaagaca acaatctttc attaaatatc
    11581 ttaacgatac cgacaatgat caattataaa ggtttttcca aaatcaccga gtttttgaaa
    11641 cgccatcctg aatttacagt ccagttgaaa gaagtggaaa gtgtcgaatt aacttacaat
    11701 gacgccaatg aacatagtga cacgatccac tttgctagaa gtttccaggc cccaccaagt
    11761 tcgattgagt ggttgcctac tgaaacagac gattttgtag cagttctacc taaaaatcat
    11821 cctttagcta gtaaaaagaa attggatcta agcgaactga aaaaggagaa ctttttgctc
    11881 cttggcccca ctacgaactt gtatcaacct gtactagatc tgtgtcgcga agctggattt
    11941 gaaccaaaaa tctcttataa aggagcaaga atcgacttga tcatcaatat gattgcaaat
    12001 gacatgggga ttgctattgt tatggaaaaa acagtcaaga atctattaaa agaaaatact
    12061 gtgattctcc ctatttctcc aacaacagag agttatcttg catttactcg taaagtcggt
    12121 gagcattctt tggcttcaga tacattttgg gagtatttaa atcaagaaga aaactaagcc
    12181 ctacattttc tgtccatcta tccacccaaa aaaagagagc gacgcatgac tttcgctctc
    12241 tttcttgcat catgtccttg tttcaatgac acctctaaca tttctcgtag ttcaataaga
    12301 aagcagcgat ttttatgcca aaagaaccgt aagaacattt ccctaatcac aaaaaaacga
    12361 ctaaaaaccc ctaaaaacct tcaatagaat ttttaggggt tttattcttt ttcctattgt
    12421 ttacttaacc gtatcattgc tgtcgttcct actccttcga tactgctata atcaatacgt
    12481 ccatcatgca gttctagaat ttttttaacc agtgaaagtc ctagcccatt cccagaaatt
    12541 tgacgacttg tatctccttg ataaaatttt tcaaacattc gatctctggt ctcttcattc
    12601 attcctacac ctgaatcggt cacttccagt acaatctctg tggctgtctc aaatagtttg
    12661 atatgaatct gtccattgat ttgattgtac tttatggcgt tatccatgat attcagccac
    12721 acttggtaca aaaactcttc attgcctgtg taatttactg cagcaagttc gatatccaat
    12781 tctagctgtt ctttctccca tttaggctga aaaaaaacga ttacttctct gatttgttca
    12841 tctaatcgat actctttctt ttccagttgg atacgctggt tttccagttt gttcaatttt
    12901 aagatgttct ctgttaattg tgaaagctgc gtgatacttt cgataatccg atataaaaat
    12961 atttggcgtt cttcgtcaga gagatttggg gcttgtaaca attgaacata tccttggatt
    13021 gttgctagtg gtgttttgaa ttcatgggat acactggaca caaagtcatt cctcagtgtc
    13081 tcgatactat tgagttcttg gaccataacg ttgaaatctt tatacagttg ctgtacttct
    13141 gctactttct gctgttcatc cattcgaatc gaaaaatctc ccgttgctac cagactcata
    13201 tttgtcccta gcgcactgat tggatgcagg atacgccgcc caacaaaaat cgatattcct
    13261 gtacccacga ccatactgaa ccccgcaaag acgaataacg ggtataacgt tggttttcca
    13321 gccgattcag caggcgagat agaatgtcga gacaataaga aaataaaacc gagaaaacac
    13381 agcagtgtca ctaagatcga aatgaagaca atactagcaa aatagatcca taattgtgaa
    13441 aatagctttt ttttcatctt taaataaccg ccttatagcc tagtccccgt actgtgatga
    13501 tttgaaaatc ttccgtcttt tcaaaacggg tccttaaacg tttgatatgt acatcgatcg
    13561 ttcgttcttc tgtattcgta tctaatcccc aaatatcatc catcaactgt tggcgagtga
    13621 agatcttgtt gggataagac agtaatttat acagaagcag aaattctttt tgaggcagaa
    13681 tcaacgaatg ctgatcttgt aacactgtat aagcatctag ctctaatttt gtttgtccga
    13741 ttatcaagct actgctgtaa ttgatctttg aacgtcgaag caatgcttcc acacgtagga
    13801 tcatctcatt gacatcgatg ggttttgtca tataatcatc tgctcctaat ttgaacccgc
    13861 gtttcttatc ctcaaaatcg gcctttgccg taatcattag aacaggtgtg tcaaatctgg
    13921 tgctacgtaa tgagtctagc aagtcatagc catccatttt cggcatcatg atatctgtaa
    13981 tgattaattc tatacgtgtc gcttctagtt ttttcagcgc atcctctcca ttcaatgcgg
    14041 tgatgactga aaagcccact cgttccaaca cagaacggta aagcaactgt aattgcggat
    14101 catcttctac tactaaaata cgattcattg atctccctct gttttttgaa aaatttctag
    14161 attttttctt gtagttcatc ttcagttaac atttatttcg tatactacga tcattgttct
    14221 gatatactta ttagtatacc gaatatttca atacgggaga agggtgatta tgcttcaatt
    14281 aaaagatata aaaaaatatt ataaagtcgg cgaaaccacc accaaagcat tggatggtgt
    14341 gtctgtcgct ttcagacaaa aagaattcgt agcgatttta ggtcctagtg gttctggtaa
    14401 aacgactatg ctgaatgtga ttggtggact agataattat gattccggtg atatggtaat
    14461 caacggaaag tctactaaag actttaagga cagtgactgg gatgcctacc gaaacaactc
    14521 tatcggtttc atttttcaaa gttacaactt gattggtcat ctaggcatta ttgaaaacgt
    14581 tgaacttggg atgacattaa gtggtgtttc taaagacgaa aaacgaaaac gggcagaaga
    14641 tgcattgcac cgagtcggct tgacaaatca tatgcataaa aagccaaatc agttatctgg
    14701 tggacaaatg cagcgagtgg ccatcgctcg agcactagcc aatgacccag atatcctttt
    14761 gtgcgatgaa ccaaccggag cgttagatac agaaacaagt atccagatca tggaattgat
    14821 ccaagagtta tcgaaagaaa aattagtgat catggtcaca cataatcctg aactggccca
    14881 tcaatacgca gatcgaatca ttgaattttc tgatggtaag atcttaacag attcccatcc
    14941 tcacatcgaa cgaccaaaag atgatcaatt taacttacgc agaacaaaga tgagtttttg
    15001 gacagcgtta aagctttcct tcaacaatat ccgaacaaaa aaaggacgta ctttcttgac
    15061 ctcctttgct tccagtattg ggatcatcgg aatcgcgatc gttctgtccc tttcttctgg
    15121 attccaaaaa caaatcgata acacgcaagc tgaaacgatg gcgaaatttc cgattactat
    15181 ttctaaggta acgactaacc agactcgtga cgatgccgga ttgggtgcaa gcaaagcgga
    15241 ttatccagac agcaaaacga ttactgcaaa agtcagcgaa gaagataaag cacagcacac
    15301 gaataagatt gatcaaacat acgtcgatta cgtaacagac atcgatccta acttaagtaa
    15361 taatatcgga tttacccgta ctacaggaat caatctttta cgtgatgtaa atggcaaagt
    15421 acagcctgtc agcttctcga atcaaaatcc tgatacggaa tctctttctt tatctagtac
    15481 gatgtcagca atgacaggtg tgggagtgtc aagtttccct acacagcttg acactagcaa
    15541 agaaaacttt ttaaaagaca attattcttt acttgccgga agttatccag cctcagcaac
    15601 agatgtcgtg ctgatcgtag acggcaataa taatactaat atcaacgcat tgaagaatct
    15661 tggatttgat gtgaaagaag acgaaaaact tgattttgat gatatcgttg gtacaacatt
    15721 caaattagta aacaacaata cttactatac aaaacttcca actgggaatt ttatccctaa
    15781 tacagattat gatgcgatgt atcagaatgc ttctgatgaa ttgaagatct cggggatcct
    15841 acgcgtgaaa tcttcttcta caatgaatct cttatctcca ggaatcgctt atagcgatca
    15901 attaacgact caaatcgtca acgaaaacaa agaatcagaa atcgtcaaag ctcaaagaga
    15961 cagtggtgta aatgtcttaa ctactgaaaa agttgacgaa aatgccaaac aaacattgct
    16021 tagttattta ggtggagaca gcttgccttc aagtatcatg atttatccga acaattttga
    16081 agacaaagaa aagatcttgg attatctaga tgattacaat aaaggcaaat cagatgaaga
    16141 taaaatcatt tatactgatt tagctggaac gatgactgaa ctgactggcg gattgatgga
    16201 tgctatcact tatgtcctta ttgcttttgc agggatctct ttagtaacaa gtatgatcat
    16261 gatcagtatc attacttata catctgtgat tgaacggaca aaagaaatcg gtgtactaaa
    16321 agctttaggt gcacgtaaaa aagacatcac tcgcgtattt gacgcagaaa cgtgtatttt
    16381 aggtatttct tctgggatat taggtgtgtt tattgcatgg ctagctacgt tccctatcaa
    16441 tagcatctta tacaacatga cggatctaaa aaatgttgct caactaaatc ctgtccatgc
    16501 gattattcta gtgatcgtct ctactatatt gacgatgctt ggcggtcatc ttcctgcacg
    16561 aatggcagcg aaaaaagacg ccgctatcgc tttgcgtgca gaataaggtt gtgacaacca
    16621 catttagatt tgagtcataa gagcgctgaa atagtagaaa acagcaagaa acgaggaagt
    16681 aatatgttcc ttgtttcgcg ctgttttttt taattatttt ttataattct ggtatacttt
    16741 tctttccttt gtaccacaac tcttctggcg tatacctgtc ttttccattt atgaatactg
    16801 ttccatctgc ttcaatcgtt acttcagtcc caatccacat attacgagaa agtgcgagaa
    16861 gattttttct ttttcctctt cctttttttc caaattgcaa ggcatcggtt atctcttctg
    16921 tccaatgaga tttcacgtat tttacttctc cgttttcaaa tgtaactttc aaaatattcg
    16981 ctatattttc cacttttact gctttaggaa atgactcctc catttttttc actttccttc
    17041 ctccaacact aagtatgcgc tttcttttag tgataagtat atcatagttt attctattat
    17101 caaaaaaacg catccattcc attgtagaat actttaccga acaagttgaa ttgttttcct
    17161 ctttttcacc ttttactata gataggtaaa gacaactaag gaggaatctc tcatgacaga
    17221 tcaaccgtat gatttaagaa aagtcatcga agaactaaaa acacttccag gtcaatatca
    17281 cgaaacagat attgaaatcg atcctgaagc agaattatct ggtgtttacc gttatatcgg
    17341 tgctggcggt acagtaaaac gtccgactca agaaggacca gctatgactt tcaacaatat
    17401 caaaggtttc cccggcacac gtgtgaacat cggaacaatg gctagtcgta aacgtgtagg
    17461 tgaaattttg caccatgatt atcgaacact tggtcgtttc ttgaaagacg ctgtagaaaa
    17521 tccaatcaaa cctgtgaaag tagacaaagc agacgctcca gcacaagaag tcgttcatct
    17581 agctaccgat gcagacttcg atattcgcaa cattttgcct gcacctacaa atactcctga
    17641 agatgctggt ccatacatca caatgggtgt agtcttagga tcagatccag aaaaaacaat
    17701 gagcgatgta acgatccatc gtatggttct agaagataaa gatacgatcg gtatgtacat
    17761 catgcctggc ggacgccaca ttggtcactt ccaaaaacaa ttcgaagcct tgaataaacc
    17821 aatgcctatc actatcaata ttggtttaga tccagcaatt gccattggca cgactttcga
    17881 accacctacc actccacttg gctacaatga actatggtgt gcaggagctt tgcgtaacga
    17941 acctattcaa atcgttgatg gtatagcagt cgatgaagtg ggtattgctc gtgctgaatt
    18001 catcattgaa gcagaaatca tgccaaatga aacaatgcaa gaagatatca acacgaactc
    18061 aggaaaagca atgccagaat ttcctggcta tactggggat gctaatccag ctgtacaagt
    18121 agtgaaagtc aaagcagtta ctcaccgaaa agacaatcca atcatgcaaa caacgattgg
    18181 tcccagtgaa gaacacgtat ctatggccgg tattcctaca gaagcaagta ttcttgcctt
    18241 ggtcgataaa gctattccag gaaaagtagt aaatgtctac aatcctcctg caggtggtgg
    18301 taaattgatg accatcatgc aaatccgtaa agaaaacgaa gcggatgaag gtattcagcg
    18361 tcaagcagct attcttgctt tatcagcctt caaagaattg aagacagtca ttttagtcga
    18421 tgaagatgtt gatattttcg acatgaacga tgtagtttgg actttcaaca ctcgtttcca
    18481 aggagataaa gatatcatcg tgatcccagg aatgaggaac catccattgg acccatcaga
    18541 attaccagaa tataatcctg gctctattcg tttccgtggg ataagtgcaa aaactatctt
    18601 tgacggtaca gttcctttcg atatgaaaga acattttgta cgtgcaaaat tccaagaagt
    18661 agaagattgg gaaaaatatt tgaaataatg aatgatctgc aactgttttg acatcataaa
    18721 aaggagtgcg gaaaatggaa caattggcac aacggaagaa aaaaatcgtg attggtgtaa
    18781 gtggcgcttc aggcaccatt tatgccatca acctagtgaa gaaactaaaa gaatatccga
    18841 tgatagaaac acacggaatc atcagtccat gggcaaaaca gaacttaaag ctggaatccg
    18901 acttatcact aactgaattc gaaagcctgt ttgattacca ttattcaaac aaagatttag
    18961 gtgctgctgt cgccagcgga tcatttttga ccgatggaat gatcatcgta ccggcaagta
    19021 tgaaaacagt cgcaggtatc tctgttggtt taggcgacaa cctgattgca cgtgctgctg
    19081 atgtaacaat gaaggagcaa cgaaagttag tcattgttcc tcgtgaaacg ccattaaatg
    19141 ccattcactt ggaaaacttg actaaattag cacgactagg tgtgcaaatc ataccaccaa
    19201 ttcctgcttt ttataatcag cctcaaacga tccaagatct tgttaatcac catacaatga
    19261 aacttttgga tcaatttgaa attgtaaatg agcattcaaa acgttggcag ggtgattaat
    19321 atggaaaaag aaacgatagt tgaagtaacc aaactaggtt tcacgatcca agctgctgtt
    19381 aaagtaatcg gtaaagactt attgatcact ttaacaggcg gagatacacc acatatcgga
    19441 acagtcacta cattttctcg tgatacagag atgcaaactg tacgtttccc tagccacgat
    19501 ggtcggttcc ataaagacga tgtcttagcc gaaaaaatag ctgtgatcat caaaactgcc
    19561 gttccgggaa gttgtacgat cacttccggt atccatgttg accatatctc caatgcacaa
    19621 atcaacgcct cttttccgat gtcagaagag ttaggttaca agattttaga ttggttggaa
    19681 aaaatagatt tccatatcaa agaaccagtt tattataaag atggtgaaaa accattatga
    19741 aagaagaggt tgtgaaatca gcgttatgac ctgagtatga gagaaaaaaa tggaaaaata
    19801 gcttctcata ttttgccgtt tttgagctaa taccgaggga cagctgattg aacgccgttt
    19861 atcaagaggt tgtgataaag ccgcttcgtt tcgagtagta agaaaaattt tgtaaacatg
    19921 ggtttccaca tttttgcata aatttgactt actaccgaga aactggcttt tgaacaccgt
    19981 ttatcaagag gttgtgacac gtcttttgtc acaacctctt ttatttttgc ttcactgtaa
    20041 ctgctacaat atcaccgatt tcttttccga tgtttttacg aatatctttt cgtagtccaa
    20101 ggatgtagca gactgaacca tctggatttt tcacgcccat attcacgata ctgccttcat
    20161 acggcacatt gtcaaaagtt gcttggactt taactcttcc agcaccgaat tcttttctta
    20221 tatcatacgg aaaaataata tatgccccgc ccttgccgac ttcggaagca tagatttttg
    20281 attcaaaaga ataaatttcc ctcattttat ttctcctatt ttttacatct agtatagcat
    20341 agcaaaaaaa agaaggaact gtgacaaaag tcttgtcgca gttccttttt tcgaataaac
    20401 ggtgttctcc tgccaactcc tcggtcacaa gtcacaatag tcaacaaaca tgagaagctg
    20461 ttttttgaaa ttgctccttg tgactcagag ttaaacggca ggctcacaac ctcttcctta
    20521 aacggtgttc aaaagcttgc atctacggca ctaagcccaa tcagatgaaa aatatggagt
    20581 gctattttta tctgattgtt cttactgctt gatgcagagc agctttttca caacctccta
    20641 catggtgttc aaaatattat tcgccttttg cttctttcac taattttgcg aatgcttgtt
    20701 gttggaattc agcagctaag gctttcgtac gttgttcttg ctctgctttg ctcatttttg
    20761 gattttcagt cattgctttt accataccgt cttgaacata agcttttgct tcactttcca
    20821 tcgtactttg ctgtttcttc actaattcag ctaacttggc tgcttggtcc gtacttaatt
    20881 ctacccatgt ctctgggatt ttgaatgtat tcactcggct gtcatattcg tgattgttat
    20941 cagcaatatt gaaccagaat ttatacatgt cgtttttgta ttcccaataa gtagttttcg
    21001 tcactttttc agcatcgccg tctgtctttt ctactttatt tgtttcgtta tccgtaccag
    21061 ttgcttttgg tttttcttgt ttttcatttg ttcggtaaag atacactttt tcttttccat
    21121 tccctaaagc tttatacaaa agcatatctg ctccttggga atcagcactg gaaacaattt
    21181 tttctgtttt tgtttccgtt actttttcca ttccaaagtg attggacaaa ttagcgacga
    21241 tcaaacttag tgaagcgacg aagattagtc cgaaaatcaa agataaaaag gtttgccatg
    21301 tttttttagc gaacacgttc gttaaagcaa aagcaagcaa gctgacaatc aaaactccaa
    21361 taatcatgca ttatcccccg ctttcattag aacaggttct tttttcttca ataaaaaggc
    21421 aataataaag ccaagaatcc caaagatgat cgctacgata aacgcggcat ggtaacctga
    21481 cagtgtggca ttgattgcct gatctttata agctaatggc gtattatcca atacagattt
    21541 gcttgggata tttgcttttg tcacattcgt caacacactg atcaaaatag ctgtaccaat
    21601 cgagcttgcg atttgacgga atgtattatt taccgctgtc ccatgactga tcaagttatt
    21661 tggcaatgca ttcataccag aagtcgttac cggcatcatg accatggaga tcccaaacat
    21721 acggatcgca taaaggatca cgatatataa aactggagtc gtttttgtca agaaagcaaa
    21781 tggtgcagtt gccgctgtca aaatgaacat ccctgtgatg gctaaacgtt tcgcgccgta
    21841 tttatcgaaa atcgcacccg tcacaggcat catagccccc atgatcaatg cacccggcaa
    21901 caacatcaag ccagaatgga atgctgattc tccacgaata ttttgaatat acaatggtac
    21961 gaccatttct gcccctacca tcgccatatt tgttacacca gctaaaacag ctgcaatcgt
    22021 gaatgtagat gatttgaata cacgaagttc caagaatgga tgttccaaat gtaattgacg
    22081 ccatgagaac aaggcgatga aaatcacacc aacaactaag aaaccaatta ctttcaagct
    22141 tccccagccg tcatctccta cactagaaaa tccgtaaagt aaactaccga atccaatcgt
    22201 tgataaaata gcggataaaa tatcaatgct aggatttgac aatggaataa cacttttcat
    22261 taggaagaat gctaaaacca agacaagaac aacgattggc agtaccatac caaacaagtc
    22321 acgccaatgg tagttatcaa tgatataacc agataatgta gggcctaaag caggagcaag
    22381 tccaataacg atccctgaca tccccattgc tgatcctctt ttttctggcg ggaaaataga
    22441 tagcatgata ttttgcaata atggcatcga tactcccaca ccgcaagctt ggatcaaacg
    22501 accgattagt aatgtactaa aattaggtgc tgtaaagcaa gtaatcgttc cgatcaaaaa
    22561 gatcgtcatg gcagaaagat ataaatttct tgaactgaat ttattgatca gccatgctgt
    22621 tattgggatc atgatcccgt tgactagcaa gaaaccagtc gttaaccatt gcacatcaga
    22681 cgctgaaata tcgaaagctt tcatcaatgt aggaaaagct gtcgtcaata aggtctgatt
    22741 caaaacggta caaaatgtac caattaataa gacaacaact aaaagtgtcc gattatatgg
    22801 ttttccgtaa atatctacgg gttggttgtt actcatattt ctccttcttt ctgaattttt
    22861 tctgaaacta ctagaatact ttagtcctaa attcgctatt tgtcaaccta cttgacacat
    22921 aagttaatac ggatataatt aagggaagca agaggacaaa aggagtgaca aaaatggttg
    22981 gggcttccct taaacgtttg ttggaaaatg atcaattggt tgttggcatc agtgaattaa
    23041 gtgatatcgt aggtgtgtct ccacgtcaat taaggtattg ggaacaaaag ggattcattc
    23101 gttcgatcga agctgatgcg aattgtccta gaaaatatcg tttacctaca gtcataaaag
    23161 tagaactgat caaaaaatat ttagatgacg gatttacttt gtcaaaagct gcagaaaagg
    23221 cagaaatccg ccaaaagaaa atgcaccatg tccgtaaagt tttttcaaaa gcaatcaaag
    23281 atatcgaatt gatcgacgaa cgctatacga ttttacaaat cggtaacttc aaagaagaga
    23341 atgctaagat gtacatcatt catgacaacg agacagacga attaacttac aagctccttc
    23401 ctgtcgatga aaaagctgac tacgaacagt tgttaaaaga actctaaacg ccactaatct
    23461 cctaagtacc aagcttttta ataagtagat gctacataaa tacttgaaaa aaggcctgtt
    23521 tgaacataag aatatccgaa cggtgatctg cgtttctttc atatagaaag gaattctcca
    23581 tcactgttcg gatatttttt tatttttttc ggttactttc ttctaataca tctgttagcc
    23641 aatttgcata ttctgtttcc cgattgatcg catgcgctaa aatcaggtag tgtccgtaat
    23701 tttcatgttt ttctttttca gtaggaaaga tcgttttttt tcgctctaat agatgaagtc
    23761 gtttttcttc atgaaggtca cgctgctgct gaataatttc tactaatgcc ggatcattca
    23821 cgtctttgac gaaatacaat ttcagaacaa attcgtctcg attaaccggt agttcattgg
    23881 tgggtgtatg aatccactct gccaattgtt ccttcccttc ttctgttaat tcataaactt
    23941 tcttttccaa tttttcacct gtgatctcta cttgatgctg aatgattcct tgctcttcca
    24001 tttttgcaag ttcaggataa atctgactat gttttgcttg ccaaaattct cctatttcat
    24061 ttttgaacga ttgattcaat tcatatcctg tcatcttctt cttacttaat aaccctaaca
    24121 aaatatatcg aagtgtattt tttcttgcca tcagttttcc ctccttgaca aatctttaaa
    24181 tccattctat cataaatgag taatcgaaaa catgtagttt attacatgtt ttaatttata
    24241 aggagatgct taaacatgaa agaatttaaa gaattggaag attttattgg aactcacttt
    24301 atctatacgt atgacaatgg ttgggaatat gaatggtatg ccaaaaatga ccatactgtt
    24361 gattaccgta tccatggcgg aatggtcaaa ggccgttggg taaaagacca agaagctgat
    24421 atcgttaaat tgacggacgg cgtattcaaa atcacttgga cagagccaac agggacagac
    24481 gtggcattgg actttatgcc aaatgaaaag aaacttcacg gaatgatctt tttccctaaa
    24541 tgggttgaag aacatccaga aatcactgtt actttccaaa acgaacatat cgcagaaatg
    24601 gaagcagctc gtgaaaaata tgaaacttat ccaaaattac ttgttcctga atttgctacg
    24661 atcacttata tgggtgatgc aggtatagac aatgaagatg ttattagcga agaaccatac
    24721 gatggaatgc cagatgatat ccgtagcgga aaatacttcg atgaaaatta taaacgagta
    24781 aaataaggtt gtgaaagaga ggttgtgaaa tcagcgttct gacctgagta ttagagaaag
    24841 aaacggaaaa atagttcctc atgttttgcc gttttttgag ctaataccga gggtcagctg
    24901 attgaacacc gtttatcaag aggttgtgaa atcagcgtta tgctttgagt aataagaacg
    24961 ctagttagaa aatagctttt catattttct aggctagtgg gcttattacc gagaagcagc
    25021 cgtttgaaca ccgtttatca agaggttgtg aaatcagcgt tttgacctga gtattagaga
    25081 aacaaatgga aaaatagttc ctcatatttt gccgtttttt gagctaatac cgagggtcag
    25141 ctgattgaac accgtttatc aaagattgta acaactgcat attcacacag ttaaattagt
    25201 gacttcaaaa tgaaataatg ctcccagcaa aaaattaggc tgggagcatt atttcgttat
    25261 tctgttcatc aaaaatcagc gttttgattc catttcatca caagttcctc ctcatttact
    25321 gcttcatctt tttgctgtgt ttgaattgta aaaccttgtg aaagatagaa atgaatagct
    25381 gattgatttt tttgatagac tgtcaaagtc agtgttttat tggtttcttt tatttttttc
    25441 attagttgcg taccgattct ttgttgccgg tattcccttt tcacaaagat tcctgcgata
    25501 aactgatcaa tcaccccagc aaaaccaata atttcttgat ctatttctgc taagtaaatc
    25561 actgcatctg gtaaagcttt cctaacagat tctacttgat tctcccaata agttgatgga
    25621 atgaattcat gagaatccaa gttagcatgc agccaaatcg atagaacaga ttccagttct
    25681 ttggcagaca attttgttgt tgtgcggatc attttttctc tccttactta ttcattgatt
    25741 ttaaaataaa aaccattttt ttgaagctct tttacaagtt ttcgcccctc aaaaaagtat
    25801 atcttctctt gttttacttt tctaatacca aaagaaacag caactttagg atcatcagct
    25861 gaaacgattc gataagttcc accaggcaat tgatccagct tgactttccc atgatggtcg
    25921 ctttgtactg aaaacggcac accatttcta gtaagtgttt ttttcttatg tttcaaaatg
    25981 aatgaactac catttaccgg tttccctgac gaatcactaa taataaatga aaaatcaagc
    26041 acttttttac ttaatctata ctgatagatt agtcgtccga taaacactaa cagtatgact
    26101 acagctatta tcgttcctgc aagaataaac cattgccgca tggttctttc ctgatttcct
    26161 tttccttctt ctttttttac cgattcgtta taaggaatcc gatgtcctgt cactagcaaa
    26221 cgatgcgtgt tgatcatata cggcgtacat gtaagcaagg taactaagtc ttctccttct
    26281 gaaatcgtta gaacagacgt gtcatctggc agtaccactt gtatattttt aacttgataa
    26341 gccaatttct cccccaaaac agtcaaaata aacgtgtctc cgttttctaa acgatctaat
    26401 tcggtaaata accgtcgatt aggtaaaccg ctgtgagcag agatcactga atgcgtcgaa
    26461 tttccaccaa gcgggaaaga ggttccttgc aagacgcctg ctccattttc aaggatccta
    26521 ccattgagcc gatcataaag tgaaatattt aattggatct taggtatatt gatacttccg
    26581 atcagccatt cctctaattg gctggatgtt gtactttcat ttctgttctt ttcattgaaa
    26641 ggatcagtac caggattgaa tccttggtca gttaatcgtt ggtttttctc ctccattttc
    26701 tttcgctgca cttcaatttc agctgcggtc cgtttttgta cttgttcgat acgtttttga
    26761 tcaataaaac tatttaaaga atccacataa aatggatata aagcgatcag taaccctacg
    26821 acgatacata ttaataaaaa caaacgaaac aaaagtcgac gagactgttt ttgcttactc
    26881 tgcttcacat gtgtcctccc ttgcaagttt ttttgttctt tcttttatta tatgggttca
    26941 ggaaaaaaat agaaaatgaa agccgatgag gttgtgaaaa agctgtcctg catcaagtaa
    27001 taagtacagc ccaaaaaaat agctactcat attttttgtt gggttgggct tattaccgca
    27061 gatgcaagct tttgaacacc gtttaaggaa gaggttgtga aaactgcgtt atgctttgag
    27121 taataagagc gctagtcaga aaatagcttc tcatattttc taggctagtg agcttattac
    27181 cgagaagcag ctgattgaac accgtttacc gagaggtcat gaaaaagcta ctttgtttcg
    27241 agtattaaga aaaattctgt ttcaaaacaa ggagatgcaa caaaacttat gtcgcatcct
    27301 ctctccttag aactttcact tatgtttttc ttgtaaaatt cataaatatt ttcatgaatt
    27361 ttctaatttc ttgcctacct ctcgcatagg atatatgatg aatttatcta aagtttgcaa
    27421 aggagttcga caattgaaaa aatatggccc atttttagca atttttttca ttgctttggc
    27481 atttctcatg cctcatttat tcacacataa actaattttg ggtgctgatg ccccattcca
    27541 ttacaatcgg ttctatgatg ccgcgcaaca aattaaatat ggggatttcc attattttcc
    27601 ttccctttat ggattccagc aaagtggcag gatcgtgaat gccgtttacg gcccattttt
    27661 cgcttattta caaggattga tcgtgttgct tgcaggtagc tggtttcatt atcagattct
    27721 ttcaaatttc attctttatc ttatttcagg attttctatg ctgattttac tgagatatgt
    27781 caatgttcga aattgggtaa gtgtaccagt agccgtttta ttcatgagta cgtattctat
    27841 tcaatactgg tctatcaacc aaggattcac tagctggggg acttgttttt atcctttatg
    27901 tatgatccct attgctgatt tcgtccttca taaaaagttc cctgttatca aagtcgctgt
    27961 ctcagtggga cttatgacac agatccattt actgtcttcg atcatgttag ctttgatgta
    28021 tatccctttt tatctttatt acttttttaa ccagactgaa aaaggaaaag cactgcttca
    28081 actgattaag tcggtcttgc tttattttgt tctgacagca aatatttggg caggattagc
    28141 tattgtttac agtgggaata agattcttcc tccctttgtt aacagagaaa tgagtcaaaa
    28201 ggcgatagat ctggatggca gttattggct ccattaccct aaggcctttc ctatattgat
    28261 attatcaggt tttttgcttt ttattttctt tcaacaaaag aacaccttat tccaaaaaat
    28321 cgtgttgtac acaagtcttg ttttcttttt tctttctact agcttgattc catggacgac
    28381 attgatcgaa aaaaatgtgc cttttattag tttgatccag tttccatttc gatttttcgt
    28441 gccatttacg ctattgcttc tactttacct tgccctttca ctgaaccagt ggtctgaaca
    28501 aaagtggttc cgtcttttaa gtatatttgg cattcttatt ttttcagcac agacgatcca
    28561 gaacttatac cagcatctgg aaaagtggga aaatgaaaca tttgtcagtc gacatactta
    28621 tctattcgat acgccggaag aagcaaggaa aacattcttc agcaaagata tgtctaccag
    28681 cttgttcgtt ttccaaaaaa ccacacctga ctatctgcca atctataagg agacaaaaga
    28741 caataaatac gaccggtata acgaagaaat actagaaaac gaaacaactt ttataaaaac
    28801 acatccaggc ggtcttttga caatcaagtg gaaaaacact ggggacaaaa ctgttcatat
    28861 ccctgttatc gtctacgatc ggactgtgct acagcaaaat ggaaaaacat tgactgatta
    28921 tgaagtaaca gatatcggga ccccaatcgt gaagcagcaa aaaggaatca acgagctcac
    28981 gcttcattat caaacgccaa tctatttcta tttcattctt tctcttactt tgattggctg
    29041 gtttaccttg ctatgtttat ttatttatca tagatacaag cttttacgtg cttaggcaaa
    29101 agggataaat acatccgatc aaaaaactct ccaaacggta taatcgtttg gagagtttta
    29161 ttttaatcag tttttttatg ttatatgtta tattttttat tcgttcacat ctaattcgat
    29221 ttccaccccg tagtgatcac tgatgattgg actatcgatc ccatcaaaaa tccgttgata
    29281 ttttttaacc tgcattcctt cagggacgaa aataaaatct atacgcaatt tttctgtatt
    29341 ttgttcccaa ccatctattt tcttttccac agtagctgct tttccttttt cattcgcgac
    29401 aacatacgaa tcttgaagaa gaaggcaact ttctcttaca gtataataac cttgagagtc
    29461 tactggatta ttgaaatcac ctaggaaaaa aagtggtacg cgagtttcca aaaagtagtt
    29521 ttccaagttt ttccactcaa aataaaagcc acttttttta tctgtccacc aagaaaagtg
    29581 gcagctcgag acaaaaatgt cctgatcatc tatctttgtt ttcccaatca agatcttgcg
    29641 tgtctgataa tcttctttct tttgaaattg ggagacggta aggacctgac tttccaatgt
    29701 ttttttcgta agcagtgcat ttccttcttc atatttatca taaccgatgt ggctcatttc
    29761 ccaactccaa aaatactctt ttccgtgttc ctttaaaagc tgaactaaac ggtaggcaaa
    29821 attatcttta cggataggta cttgattctt taccggacag aacttcatta gcttcgcagg
    29881 ttctacttct tcagattcca gtaattggtt gatttcttgt aaagcaatca cttcataatc
    29941 ttctaacagg atcttatctg ctaattcttg caattttttc tctggttctg gctcaagcca
    30001 gctatgcgtg ttgagtgtca tgaatttcat tggttttctc cttgtcttca tttcgaaaca
    30061 aaagggttgt gacaaaattt ttgtcacaac ctctccagca aatagtgttc tcctgctaac
    30121 tcctcagtaa taagctcaat ggaccaggag ctattttttg tttggctgtt tttatcactt
    30181 ggtgcagggc agctttttca cgacctctcc actaaacagt attcaaactg ctgcttctcg
    30241 gtaataagcc caaccaaacg aaaaatagga ggagctattt ttgtttggct gttcttatga
    30301 cttgatgcag gacagctttt tcacaacctc tccttacatt ttaatggagc cgatcacttt
    30361 accagctgtc actgtaccta attgcttgat cactacttct tctactttat cgtttgtaaa
    30421 tacgatcatg atcgttggat cttttttttc gttttggatc acatcaagat ccatctcagc
    30481 taatttcgtt cctgttccta cttcttggcc ttctttgaca gcaatctcaa aagctggctg
    30541 attcatttgg actgtatcga ttcccatatg gatcaaaact tcgataccat ctttcgtttc
    30601 cagcccaatt gcatgtttgc tagggaaaat acttgtcact tttccagcga tcggcgcaac
    30661 aacttctctt gatgttggaa taacagcaaa gccgtcaccc atcatttttt gtgagaatac
    30721 cggatctttt acttcagata aaggaatcac ttctccagaa gctgcggaaa ctagttcttg
    30781 ttctatacct aagtattgct tactacctgc ttgtccattt cctgtagaaa ccatttctgg
    30841 ctctggaatc tctgctcctg attgcagcag atcttcgata tctgatttca agacatctgc
    30901 ttttggtcca taaactgctt ggactccatt gtctttgacg atcaatccca tcgcccctgc
    30961 tcgtttccag gcttcttcag tccctacttt ttctcgatca tttacactta cgcgtaaccg
    31021 agtcatacaa gcatcgacat ctttgatatt ttcttttcct cccagcaaat gaatgatctg
    31081 gaccacttgc tgatctgctg ttcctgttcc gctgttagat acaacggttt cttcactgtc
    31141 attgtcgtaa tttccgttac gtcccggtgt agcaaagttg aattttttga tcaagaaatt
    31201 tgctaagaaa tacgtaacaa caccaaaagc gatcacacac aacacgaagt tgataagatc
    31261 tccacctaga cccgctttga tagctaacgg tgtccgagtc agcaattcga tattcccaaa
    31321 tgaatggacc cgcaatggca agatatctgc catcgcaaat gcagcccctt ggatcactga
    31381 ataaatgaca tataatggca cagcagcaaa cataaacatg aactccaatg gttctgttac
    31441 acctgttaga aagacagcca acgctgctga aaaatacatt gatttatatc ttgctttctt
    31501 atcaggatcg acattacgat acatcgcaaa agccattccc atcaagatac ctgaagaacc
    31561 aatcatttgt cctactttga aacgagccgg cgtccagtta tgcaacacaa actcatattg
    31621 cgacatatcc cctgcacctt taagattcac taaatcagtg gcccaagcca accataacgg
    31681 atcttgccca aatacttgtg tccccgcctg tgcgcctgat aaaatctcat acgatccgcc
    31741 aagctgtgta tagttgatag gaatcgtcag catatgatgc aatccaaatg gcaatagtaa
    31801 acgttctaat gttccaaata aaaacggtgc tagaatcggt gcgctttctt gtgattctgc
    31861 aatccataaa ccaaaattat tgattccagc ctgtacgttt ggccacacca cagcaagaat
    31921 caatgccacg attgttgacc ataagataac aacaaacgga acaaagcgct ttccattgaa
    31981 aaatgacaaa gcatccggca attttctata attatagtac ttattataag ccattgcccc
    32041 gacaaatcca gcgatgatcc ctacgaatac tcccatattc aaagctggtg cttccaatac
    32101 acttgtaaaa aatcctttaa ccatgatctt cgtaccgaac agagtgtggg taaatgcatc
    32161 ttcattcgca agcatgtcac ttgtgacacc aaagatagcc ccagtgatcc gattgattaa
    32221 aataaatgag atcccagctg caaatgctcc gcctgctctt tcttttgccc aacttcctcc
    32281 tattgctaaa gcaaataaaa tatgaagatt accaataatt gcccaaccaa tattttcaat
    32341 tactccgccc gttgtgacaa gcggcgtcca atcaggattg atcaagggaa ttgatttccc
    32401 tatactgatc atcaacccag ctgccggcat aactgctacc acaaccatta aagcctttcc
    32461 aaatttttgc caaaactcaa aactaaatat ctttttcatt ccgtttagct cctttacgca
    32521 atcggtttcg ttaaacgtat tatagcgtgc gttttctttt ttgtaaatgc tttatttttt
    32581 atttttctgt ctataccatt ctataaaacc tataatacgt gtgttccctt ctataatttt
    32641 ctcctaaaaa tttatttttt taagcttttt tctatgaaat attttctttt gtctattgac
    32701 ttgtgcaatc ggttgcgttt attatgaacg tataaaacag ctcattagga ggagaaaaat
    32761 gaaacagatc aaacgactat ttgctattga tccatggaaa atcagcacga cacaattaga
    32821 taaaaaaaat cttcgactgc aagaatcttt aacaagtatt ggaaacggtt atatggggat
    32881 gcgcgggaac tttgaagaaa cttactcagg ggaccaccat caaggtactt atttggcggg
    32941 tgtctggtat cccgataaga cacgtgtcgg ctggtggaaa aatggttatc cagaatactt
    33001 tggaaaagtg atcaacgcct tgaactttat cgcgatagat atttcgatca acgatcagct
    33061 gatcgacttg gcttctttgg aaccagaaga cttttactgg gaattagata tgaaaaatgg
    33121 tgtattatct cgtacattca caatcactac ttctactaat aaagtacgca tttccttcga
    33181 acgttttctg agcattgtca aaaaagaatc agcttatatc tatttaacta tagaaatgct
    33241 tgaaggtagc ggaacagtca aactcgtatc aaaattggat ggaaatgttc aaaacgaaga
    33301 cagcaactat gatgaacatt tttggaatga gattgatcgt ggaactatag aagaaatcgg
    33361 ctatttgacg actaaaacta ttccaaacaa ctttgggatt gaacaattta ctgttactgc
    33421 agcaatgcgc catttcgtta atggaaaatc agtcatccct gactatcacg aagatacttt
    33481 agcattacat ggttgcttgt ctgcagaatt atctcaaggt gagacatggt cagtggaaaa
    33541 agaaattatc gttcttacta gtagagatat tccagaagcg cagcaagcag aaaaagctgt
    33601 ctcagaatta acgaaccaga caaacaatta tatccaagca aaagaagagc aaacagcggc
    33661 ttgggcagaa cgatggaagc ttgccgatgt ggtcatcgaa ggagacgaag aagcacaaca
    33721 aggtattcga ttcaatttgt tccaactatt ctctacttac tacggcgaag atgaacgatt
    33781 gaatatcggc cccaaaggat tcacaggaga aaaatacggc ggagccactt actgggatac
    33841 agaagcgtat gctgtccctc tttatcttgc tttagccaaa cctgaagtaa ctaagaatct
    33901 gctgaaatat cggcataatc aactgccgca agcaatccac aacgctcagc aacaaggatt
    33961 aaaaggcgcg ctttatccta tggtcacctt cactggtgtc gaatgccata acgagtggga
    34021 aatcacattc gaggagattc accgaaatgg cgcgattgcc tatgcaatct acaattatac
    34081 gaattacacc ggcgatacgg aatatttgaa aaatgaagga ctggaagttt tagcagaaat
    34141 cgcacgcttc tgggcagacc gtgtccattt ttcaaaacga gcaaataaat acatgatcca
    34201 cggtgtgacc ggcccaaacg aatatgagaa caatatcaat aacaattggt atacaaatac
    34261 gatcgcagct tgggtcttgc gttacacgcg agaaaattat ttaacttatc aaaaagaagc
    34321 tgctatcact atcagcgaag aagaactagc caaatggaaa gatatcgcag agaacatgta
    34381 cttcccagtt gacgaagaat taggaatctt tgtccagcat gacacattct tagataaaga
    34441 tctcatgcct gtatccgata ttcccacaag cgatcttcct ctgaatcagc attggtcttg
    34501 ggacaaaatc cttagatctt gcttcatcaa gcaggcagat gtactacagg ggatttattt
    34561 cttcaatgat acttttacaa aagaagaaaa gcaaaaaaac tttgatttct atgaaccaat
    34621 gactgtccat gagtcttccc tttcgccaag tatccattcg attttagcag cagaattagg
    34681 aatggaaagc aaagctgtag aaatgtacca gcgaacagct cgcttggatt tggataatta
    34741 caataacgac acagaagacg gcttgcacat cacttccatg actggtagct ggttgtcgat
    34801 tgtccaagga tttgctcaaa tgaaaactgc ccatgatcag ttgagattcg caccatttct
    34861 gccaaaaact tggaaagctt attctttcca tatcaattat cgcggacgtt tattgttcat
    34921 ctcagtcaca gatgaacaag ttactttcga gttattagaa ggttctcctc tagaaattta
    34981 cgtctatgaa cagtcttatt ctttagcgga tcgtctagaa ataacgctaa gaaaggagga
    35041 agcaaatgtt taaaggggta ttgtttgatt tagacggtgt cattaccgat actgctgaat
    35101 tccattatcg tgcttggcga aagcttggtc aggaaatcgg cattacgatc gaccacacat
    35161 tcaacgaaca gctaaaaggc gtcagccgag aagactcact ctctttgctt ttagcttatg
    35221 gcggaaaaga acactctttt tcaaaggaag aatttgcaga attagcgaaa agaaaaaacg
    35281 attattattt agagatgatc cagacgatcg aaccaaaaga tgtcttcccc ggggtcgtgc
    35341 ctttactgga ttctttaaaa gaagaaaaaa tcaagattgc tcttgcttct gcaagtaaaa
    35401 acgggccatt cctacttgaa aaaatgggtc ttacacctta ctttgatgct attgccgacc
    35461 cggcagaagc aacaaacgga aaacctgcgc cagatatctt cctccttgca gcaaaagctg
    35521 tcggactaaa agcagaagaa tgtatcggga tcgaagacgc gcaagccggt atccaagcca
    35581 tcctctcaag tggcgctcaa ccaattggcg tgggacgtgc tgaagacctt ggagaggaga
    35641 tcccgcttgt ccctgatacg acttttctta cgatcgatta cttgaaagaa aagtggcatg
    35701 accatggata atccagagat ctccgtcgta ccagttccag agactgaaat aaagaaaatc
    35761 acattgaaga acgactactt agaagtcgtt cttctcaatt acggtgcccg cctgcaccaa
    35821 atcttcgcac cagacaaagg aggaaaatca gaaaatgttt tattgtctta cgatcgtttc
    35881 gaagatgttc taacagacaa aagctttttt ggagcaactg tcggacctgt agccggaagg
    35941 atccgggatg cttcttgggg tgagcataga ttggagaaaa actgcggatc acaccatatc
    36001 cacggtggca cgaaaggctg gtctttccaa ttttgggaag tagaagtttt caaaactcca
    36061 tcatcaatag gtgtggtctt ttacttaaaa gatgaatttt ctacctatcc aggaccaatc
    36121 actgctacga tcacttaccg tttaacaaaa aacgaattag agatgacaac ctctgctagt
    36181 agccttgttg aaaccatctg caatccgacc aaccatgcct acttcaacct ttcaggaaat
    36241 ggaacaagag acatctatga acatcagtta acggtctttt tagatggtgt gcttgaatta
    36301 gatcaagaaa aactgcctac tggaaattgg acaaaaaaag aaaaactgcc aatcgacttt
    36361 agaaaatccc caacactgca agagatcctt gcatgttatc cagatggact agatgatgta
    36421 tttcttttgc atcatcctag gctttccaaa acttccttac aattattcga gaagcattct
    36481 ggtcgccaaa tgactatagc aacttctaat aaaagtatgg tattattttc tacgactgga
    36541 ttcgaagctg atttctctgt caatggaaaa cagatgcatt caaactacgg attagcaatc
    36601 gaaccgcaag aaatccctga tatcgttcat ttccccaaat ttggatcgat caacctccat
    36661 cctggtcaag aacggatcag tcagacgatt tatcggttct ctgcacaata acaagagaaa
    36721 ggtgttttta tcatggctat taccgtaaaa gatgtggcga aaaaagccgg tgttgccacc
    36781 tcgaccgtct ctcgtgtcat caacgatcat cctagtattt ccgagacaac aaagaagaaa
    36841 gtccgaaaaa ttatggatga actaggttat gttcctaaca tgactgcccg caatctagga
    36901 aaacgcattt ccagtgccat cggcgtaatc ttaccccctc ttgattcaaa agagcggatc
    36961 ggtaacccat tttatcttga gatcatggaa gcaatcaacg aagaagcgcg gaattatgat
    37021 atgactacag caatcgctac tgctaaaaat tttgaattgc tgttagagaa cgtccagcgt
    37081 atgcatttac aaaaacaagt agatggtttt attctagtgt attcagatag tcaagatact
    37141 gtcattgatt atttatacca aaaccacatc cctttcactt tgatcggaca gccttatcat
    37201 catgagaacg aaatcgttta tgtagataat gataaccagc ttctaggtaa acaagcaaca
    37261 gaatttttga tccagaatgg acataagaat atcctgtttg tgacaaacac gactcatgaa
    37321 agtttgtatt tcgaacgata tttcggttat caaaaagcaa tgatgatggc tggtcttcct
    37381 gcgttatcca gtgtagtact agagcatccg gaggattatc tgtcctttga gaaaacgttg
    37441 aaagaaaacg aagccacagc attggtggtc attgacgata tcttcgccct tcgcacgatg
    37501 cagttggcgc aaatgtatgg ctatgtcatt ccagagacac tctccgtcat tagcttcaac
    37561 aactcgatct tctcaacatt aacacaccct taccttacaa gtatcgatat cgatatctcc
    37621 gaattaggac gtgtcgctat gcaaaagctg cgcgaattga tccatgaaga attgagcagt
    37681 ggcgtacgtt tggtcatccc tcatcgcttg atcaaaagag agacagtcgt tcctttagaa
    37741 aacccatact aaatagctga ctcactaaat acgctgacca tttatcctat ggtcagcttt
    37801 ttatgtaaaa gaagatacta cttctaacac attgtttatc tgtaaaaaag agcgtgggac
    37861 aaaagtaaag aacacttttg tctcacgctc taaacacgta taaacggcgg aagcagaagc
    37921 aactccttcg gaaataagct gaaattcaca aaaatttaaa aagcaatttt cttgagtttc
    37981 ttcttatttc ttggagttaa acgcttctgt cccagcctct tttttccttc cttcaatttt
    38041 ttacacgtcg acgattcaat aaaaaaccgc ctaatattgt aaagacaggt gcaagaatcg
    38101 agaaaaaggc gaatggcaag taatgcaacg cgctaacttt catcgttccc ataatgaatg
    38161 tgccgctgac tccccacggt acgagagaat tgacggtcgc acctgaatcc gctagtgttc
    38221 gtgtcaaata ggtttttgat aagccaacgt catcaaaaga acgcttgaat gtttctcctg
    38281 gaagaatgat ggacagatac tgttctccaa cgatcagatt gattccgata cagctcaagg
    38341 cagtaaaccc gactaaacga gaaggtcggt ccatcttttc ttttaattct tgaacgatgg
    38401 tatcaacgat cagatatttg atcagtaacc cacctaatgc caatgcaagt aaaatcaaac
    38461 tagcagaacc taacatactc atgatcccgc ctcgagaaag cagttcatct agctttggat
    38521 caggtgtatt tgcgacataa ccaaccattc atcaagatgt ctgctgcttt tccgaccgtc
    38581 aaacttttct catggataaa agaaagaacg agagcagctg tcgatcccgc tagtaatgta
    38641 gggatagccg gaattttttt gattgccccc ccaaataaaa taactagtgg aatcaatgtc
    38701 caaggagaga tccaaaagct cgctttcatg ttttggatca tttcattgat actagctaga
    38761 tcggctgaat gactgttatg tcctaatatc gtataaaaaa tcaacgaaag gacgaatgct
    38821 gggaaatccg tataacgcat accagcgata tgttcgaata gattaactcc tccaataccc
    38881 gctgccaagt tggtcgtatc tgataaaggc gagcagttat tccctaaaaa ggcaccggaa
    38941 acgactgcgc ctgtagtcat tgcatcattg aatccaagta aatgaccgat ccccaaaaaa
    39001 gcaattccaa tcgtcgaaat cgttgtaaat gaactgccga cagtcactcc gacaattgca
    39061 caaacaagaa atgctgtcgg taaaaagaaa cgcacagaaa caagtttaaa tccataaacc
    39121 ataatcgtag ggatggttcc agataaaatc catgaagcaa ctaagacacc aatcaaaaga
    39181 aaaatcagga ttggaatgat ccctggagtg attcctttga tgatcccgtc atggatctca
    39241 tcccatgtga actttttaaa tctgccataa aacaacaaac acatgaaagc tgcaaggatc
    39301 gggatatgtg gcgagagctg gaatccgatg atcagtactc ctaggagtgc caacaacacg
    39361 atcaatacag cgatactttc ttttaaagaa atatttttat tcatcgtcga tctcctattt
    39421 caaatgaaaa ggccctgcca tgaaaaaact attcacttgg caggacctcc tactaaatca
    39481 gcgacaaaac gtcggctgaa agacttattt ttttattttt cttctaaact tttttctacc
    39541 tcaatccccc aagaatcttt cttgaagtga ttgatgatca atggaataac gaacatgacc
    39601 actgtgatag ctgctactaa taatgcatca ctcaatgtcg ctgtacctaa tgtagcaaat
    39661 acgacaacga tgatagagaa gatcagcatg cagctgacta cccaagctaa tccgtttccg
    39721 tttttaccaa ttcggtaagg acgttcgaat tctggatgtt tcttacgcat tttaagcaat
    39781 gaaacagcaa tcaaaatgta cacgatacaa taaataacag ttgtagcatt tgtaagtgtc
    39841 aagaatacag cacttacgtc atccattaca ccataaagca aagcaaataa tgaaataacg
    39901 attgattgtg ttagaacgac atttctagat acgccgtatt tgttttcttt atggaatccg
    39961 aattttggtg gaaggaatcc ttcacgagct acttggatga ttgtttttga tggtccagta
    40021 acccaagctg ataattgtaa aagcacacca ataaatacca tgaagctgaa gatatttccg
    40081 atcacttctg gtaagcctag gatttgacag tcaatcaaga taggctgcgt gatatttgct
    40141 aattccattt ttccatctgg tacgacattt gctacaagca tcgcattgat gacattcaat
    40201 aaaactaatc cgatcaaagc gataaatacg ccttttgtat aattttttgt tgcgtctttc
    40261 aaacgaggca tgtaaacaga actcatttcg atcccaacaa aaataaatgt gataccagct
    40321 aagtatttca atgaatcaat atgttccaag tcagggaaag cttttgacca tgaaaagtca
    40381 cctagatagc cgtttgagac tagtccgact ttgaaggctg ccaaaacacc taaaacgaac
    40441 atgatgacta ctgggatata tacccctagc catacaccga tgttcccgcc gacttttgcc
    40501 atatcgaatt tcaagttcaa gatcgtgatg atccagtaga taactaaaat acaacctaaa
    40561 acgaaccagt gattattgcc aagttctaca ttaccaaatg tgtttcctaa caatggtcct
    40621 aaagtagaag cgaccattac catacctggg aacatttgca cccataatag ccatgcaacg
    40681 acaaatcccc atttgctgcc cagtgctgtt tttacccata actgaggacc gccttcttga
    40741 ggaagcatcg tggaaagctc accggaaacc attgatatcg gaccggcaaa aaacaaaact
    40801 gcaaaaattg aataaaaaat caatgtccaa ccgactgcgg ctaacgtagg aatactccga
    40861 accgttgcac acagtgccat tgtcagaccg ataaaggtcc caagacccat tttacttact
    40921 tcagatttac tcaccgttga cactctcctt gattttttgg ataaaataac ggtgtctttg
    40981 aagtagtttc agcaataaac gaaacaattc agcgaatatt tgaggggatt ctttgagttt
    41041 attgcttgaa gggtttcttc aaagacaacc tcaaaacaaa gggatcgaag agcttaggtc
    41101 tccccttgct cttcagatcc aaacatgcgt cagaaacagt tagtattcaa gctgttttct
    41161 aacatgatta ccttgcttat tttgcttcgc ttgccaataa ttggtctgcg tagatttttt
    41221 ccaatttttc ttgaagagct gctttgattt tttcagcata ttcttcaaag tgttcttctt
    41281 tgttcatgta tggtgtcatt acgctggcac gcaatacagt tacttttccg gcacggttcc
    41341 attcttcatc tgagaatcct agttggttca caaattgtaa tgggctgttg ccatagtctg
    41401 ggatagcaaa gtcagtatgt gaagttaaga actcattacc gtaaatgctt cctttcacgt
    41461 atgaagaata atcatatacg tcatggttca atttattcat tgcaactaag tcatcgttgc
    41521 ctttttcttt gaatacatag tctaccatat tgaaatctgg ataagttaat ggatgaactt
    41581 cgatttcttt gtctcctact ttaaatgaca agtcattcaa gaagttgtag aaacgatgtg
    41641 caccttcgat tgatgcaccc attaatttac catatcctgt gacattcaaa ggtaagacat
    41701 ggtgtgctgc ccaaacgctg gctgctgttg cccctgcttt tgaaccttcc aagatataag
    41761 ccccaagtaa tgctgggata tctgcgcctt tttcaaatac atatgtcgca aagtaagaga
    41821 taacgtctct catgcggata tctttgatga cgataccacc ggcagaatat ggaacatagc
    41881 ccattttatg tgggtcaatc gttacagatt ctgcttcttc gattgcttta tatgcactgt
    41941 gtacttcttc taagatataa tctttgtttt ctgtaaagac attgtatttg taatgaacat
    42001 cttttaaatc ttcaaatgga atgaagttgt tgtcttcgtc taagaaaatc gcacggccgt
    42061 atccgccata agcagcatct acgtgtaagt agaagtaaat accgtctttt tctaatacgc
    42121 gacgcaatgc aacgatttta tcgataccgt cgattgctcc ttcttctgtt gatcctacaa
    42181 caccgactac acctaggatt ggtgtttttt cagctgctag accacgaacg attttttcaa
    42241 gttcgttgat gtccatgcga tagttgtggt caactggcac tggaatcact tggtctaaac
    42301 cgataccgat gatgtcggca gcttttagcc atgaatagtg tttagtttgt ggaaccaacc
    42361 attttcctaa tttttctaaa tgttttccgc tacgtgctga gtgagctttg atttcgtcga
    42421 ttttttctgg gacgctgtct aacagattca tgatttcttc tgttgacaag ttcattaatt
    42481 cccaatcgct ttttccagca actagttcag gtgtcacttc tttcattgca agcggcaatg
    42541 atttgatgtt gcgggcatac caaagtcctt ctaagtttgc taaagaacca tcagcaacga
    42601 tgtggcccca gccatcttta tagctcatta attttgcaaa ttccattcct acttcttctt
    42661 ccatttggct tgttgcagga gaagattcat aggcaacgtt attaccattc catagcatag
    42721 caaaattgta cgctagtaaa gatggcatca atgtttcaga gttcatatga ccccagtaac
    42781 gtccggcatt atgccaagga acggaatggg tacgcatccg cgctgaaatt tctgatagaa
    42841 catcctttgt tttattcaca gtgtgttcaa aactagcact gcttttttct tctggcgtaa
    42901 taataggcat gtcttgaggc atgtagtttt gacgccagcc taaatgttca tccaccaatt
    42961 cattcaacaa agctttatag atttggccgt tctcagcttt gtccccaatg aatagggcat
    43021 ttaggtttag atctttcgac aatgattcac tcatagtgaa accctcctaa aaaaatattt
    43081 aaattttgtc gagccctaca ttacacctgt tcttctattc tgtaaactaa gttttggcct
    43141 gatttttaat catattttaa tatgtatcaa ttatccgaat tgttcacact tttgaaataa
    43201 ttaaaaaaaa cgagggaatt tacaaatgta aactccctcg caaagattgt attaacgaca
    43261 accagcgttc tattttagga tgggtttcaa aattggaatg ttgtaatagt atttcccttt
    43321 ttcaaggtaa aaacttacta aattctaatc aattactttg gccaaaaagt aatttttctt
    43381 accttttcga ataaccacaa acttaccatc gaattcatcg gatggattta tgacaaaatt
    43441 taaatcggta acgcggtcac cgttaatact tatagctccg tttgaaacat cttcacgtgc
    43501 ttgacgttta gatggttcaa tttttgtgga aacaagcagt tccacgatat tttcaggtgt
    43561 gcttgaaatt tcaacgttcg gcattttacc gaatccttgc gcgatttctt ccgcatttag
    43621 ttctttaata tttccagaga acaatgcttg cgttattttt tgcgcttctt tcaagtcttc
    43681 ttcactatgc acaaatcttg taacttcttc tgccaaacgg cgttgtgctt cacgtttctc
    43741 aggttctgtc tctacttttt tcgctaagtc ttcgatttct tcttgagaca agaaagtaaa
    43801 gaatttcaag tatttcacta catcgcgatc atcttgattc aaccagaatt ggtagaactc
    43861 aaatggtgaa gttttcttcg gatcaagcca aacggcaccg cctgcagttt ttccgaattt
    43921 cgttccgtca gccttcagca tcaatgggat cgttaaaccg aacgcttctg cttctggtcc
    43981 ttctaatttt cggattaggt ctaatccagc tgtgatattt ccccattggt ctgctccacc
    44041 gatttgcaat tgcacatcgt atgttttatg cagatgcaaa aagtcgatag attgcaggat
    44101 ttggtaagta aactctgtaa atgagattcc tacttccaaa cggctggcaa cgatatcttt
    44161 tgctaacatc gtgttgatgt tgaagttttt accgtagtct ctcaaaaatt caagtaaaga
    44221 gatttttgac aaccagtcgt agttgttcac aaatgtgata tttgcatctt taccaaacaa
    44281 ttttctcatt tgattggaaa gtgcgtccac gttatgttgc acttgttcca tcgtttgcaa
    44341 cacacgttct gttttgcggc cgcttgggtc gccgatcgtt cctgttccgc cgccaatcag
    44401 aatatatgga tgatggcctg ccaattggaa tcttttcatc atcataaatg gaatcaaatg
    44461 tccgatatgc atcgaatcac cagttggatc aacgccgcaa taaagtgaaa tgctcttttc
    44521 ttcaacgagc tcgcgaagtc tttcttcgtt tgtttgctga ttaatggcgt cgcgccaagt
    44581 taattcatca ataatattca ttttactgac ctccgtgtag tttttttatg aaagcaggaa
    44641 cctgctagca tatgtaatta attatttctt caggatagga taggaaataa aaaaagtccc
    44701 ttggcatata agccaaggga cgaaatctcg cggtaccacc caatttgtat gtctagatat
    44761 ccaacatacc tctcgaacat ttaacgctgt cgcgtggcaa tcactgccaa agactcctga
    44821 aatgtaattc gctttaaagc atgtactggt ttgcagcgac caccagcttt ctgaaacatt
    44881 ggctttaaca actacttcgt ttcgatcttc gtcttgttat tattaatatg tgtctatcat
    44941 agagcgcaac tttttctttg tcaacagaaa aaggatattt tttttaaatt cctcattttt
    45001 tcttttttga atccgctcta attccgaaca ttttattttc aattattgtt aaaagaaata
    45061 actttttctg tattttttct gcaatttatc gagaagtcac tttactttgc ctcttattct
    45121 ttcttcgtta caataaggaa tgggacaagt aaaaaaatga aaaagcaagg gacgaggtat
    45181 atggaaaaaa agcaaaaaat tattttagga gccacttctg ctttaactat cgttatttta
    45241 attctaagtt tgttttttgt catccgatca tctacaaaaa aagaaccaat cattcctgaa
    45301 aaaaaaataa cagaaaaagc aaaagaaccg acagatgata agcaacaact agttactcaa
    45361 gcaaaaaatc tggctcaaag ctacgattat gaccaagcga ttgcgttatt ggaaaaagat
    45421 agtaagaacg gatctactga aacacaacag cttcttcaaa cactaaaaaa ggagaaagaa
    45481 caactgatcg actggtctga tcctactcag atctctcatg tctttttcca cagcttgatc
    45541 gtggacccgc aaaaagcctt ccactctcaa caggcacaag gatacaaaga ttatatggtg
    45601 actgttgaag aattcaaccg ttcgatcgaa caactttatc aaaatgattt tgttttagtt
    45661 aatttgaatg atttgatcca aaaagacgaa caaggaaatc tttcctttaa cgggcttgcg
    45721 ctacctgaag gaaaaaaacc attggttctt tcacaagatg atgtcagcta ttatgaatat
    45781 atggataatt ccggttttcc tagccgattg gtcgtatcaa ataacaatga aatcaaaaat
    45841 gtctataaag agaaagataa agaagaaatc ggtgactttg acatggttcc tctgatcgat
    45901 gcctttgtca agaaacatcc tgatttttct tatcgaggcg caaaaggtac cttggccctg
    45961 acaggttaca acggagtttt aggttatcga acatcaaaat ctcaatatgg agacaatgaa
    46021 aaaacaaaaa aagagattaa agaagctaaa aaagtggcgg aacagttgaa gaaagacggc
    46081 tggagctttg cttcccatac atggggtcac ttgaatatga ctcaagcttc actagaagat
    46141 gtaaaaaaag acaatgaatt gtggcagcaa gaagttgcac ctatcctagg aaaaacaaat
    46201 attctgattt atccatttgg tgcagacatc agcgactggc agccttattc agcagaaaat
    46261 caaaaatttg cttacttgaa gagtcaaggt ttcgatattt tctgtaatgt cgatgcttct
    46321 acaccagctt ggggacaatt aggtacggat ttctatcgaa atgctcggat caatatcgat
    46381 ggcattcgtt ttcaatctga tttagacgga aaaaatccta ttcttgatcc attcatcaat
    46441 gtccatgatg tctatgacaa agaagcacgc gaatctgctt gattttacgt catttatgaa
    46501 ccaaaaaagc cgaactgaca ttttatcgtc agtttcggct tttttatgct ttatttcttc
    46561 ttcggtgcga ttcccttgat caggacttct gtccattctg ctgtatatgg aagcagtttt
    46621 gcgtatatct ccggcttaga aattccttct accattgctt gaaaatagag gatcaagaac
    46681 tcatccgaat atttcaaatc cacttttcct tctttccgcc ctcgatggaa aagatcaagc
    46741 atgatactga aactttcttg cgtatacgca tccatcgcgt cagaaaattc ttttttttct
    46801 ttttttgtat agtatgtcat caaatcgata taaaattgtt tgttcactcg attgagataa
    46861 cggattttgt tttcactcat ggcaatcagt gtttcttcaa atggaagatt ttccgcaatc
    46921 aacgctttcg cttcttgccc taaatcattc ataaatgcaa aaaatacttc ataaatcagc
    46981 ccttccttgc tgccaaaata tttaaaaatc gtcgctttac ttacctgagc gttctcagct
    47041 accttatcca ttgtcactcc agcggttcct atgtctgtgt tcatcaagtc aaaagctgct
    47101 tgtaaaatct ctttcttttt ctcttgtgct ctcttttcaa aaccgttcat ttgtagagcc
    47161 tcccgtaatt ttaaactttt ataatatata tagttcaaat ttattctgag gtttattata
    47221 actatctatt gagaaagtat caagctagca attccttgtt tatgaattca ttgacagaaa
    47281 tttataaaaa gaatattatg tactaaaata ataaaaaaag ttttataaaa aggtataaaa
    47341 cctttttatt aaactattta atcttgttta gtatatattt ttagaaaaag gagtggggtt
    47401 tttatggcag aaatcgtcaa agtcacacat ttgaaaaaga gctttggtcg tttcgaagct
    47461 ttaaaagatg tctctttcac cgtacattca ggtgaagtcg ttggatttat cggaccaaat
    47521 ggttctggaa aatccacgac gattcggaca cttttaggga ttataaaaaa agacggcgga
    47581 acggcaacga tttttgggca agatgtatgg gaagatagtt tatctatcca tgaacgtctt
    47641 tcttatgttc caggcgatat ctctttgtgg ggaaatttga ctggaggagc gatcatcgat
    47701 ctcttcatga agcttcatgg aaaagggagt gctcaaaaaa aagatgaact gattcaacgt
    47761 ttctctcttg atcctaagaa aaaagcaaaa aactattcaa aaggaaatcg ccaaaaagtg
    47821 ggcttgattg ctgctttggc tgttgattcg gatctctatt tatttgatga gcctacttct
    47881 ggtttagatc ctttgatgga aacgattttc caagaagaag ttgaaaaatt gaaagaacag
    47941 ggcaaatcca tcctactttc ttctcatatt ctcagtgaag tcgagcgact agcggataaa
    48001 gtcgtgatca tacgcgaagg aacactcgat gaagaaggaa cactcgatga attgcgtcat
    48061 ttgactcgtt cgaccatcac tatagaaaca gaagcagaga atagtcactt agcacaattg
    48121 aacggtgtcc atgactttgt gcaaaaaggt cacctcgctc aatttgctgc tgataacgaa
    48181 gctttcgatg tgattttagc tgaagcgtcc aaattaggtg tgaaaaaatt tgaatctatt
    48241 ccaccgactc ttgaggattt attcatgaga cattatgaag gatgaggagg aagcgaaatg
    48301 actgataaat tttcacgctg gtccaccctt ttttctcaaa accttagccg tgactggaaa
    48361 aagatcctga tatggctagt cggtgtcact gctttttctg gtggttttgt ccctgcgttt
    48421 gaagaattga cttccggaca aggattagct ggattatacg aaaccttgca aaacccggca
    48481 atgattgcaa tggtcggacc aactccagct tcgaatgctg ctgagtatac tttaggagcg
    48541 atgtatgcaa atgaaatgtt gcttttttgc agtttgtttg ctgctgtgat ctctgtttta
    48601 cacgtggtga gccaaacgag aaaaaaagaa gaacttggtc tgattgaact tattcgttcc
    48661 tttcgagtcg gacgtcaagc aaactcttta gctgtcatcg ctgaaagtat tctgatcaat
    48721 ttgcttttag caatatcgat cagctgtacg atgatttttt tccaagcgga ttcgatcact
    48781 gcagaaggtg cttggctttt tgggctatct gtaggtagta tggggatttt ggggagtgcc
    48841 gttgcactgt ttgctgcaca actgatgcca agttcagcca gttcgaatgg tctgtcttta
    48901 gcgtttttag gtggacttta ccttctacga gcaataacag atgtagctga ttcctccctt
    48961 tcgatgtgga atcctttagg ctggtcttat ttgacctatc catttacaac taacaactgg
    49021 attcctttgc tttatttgtt tttgttcagt ctaatcttga taatcagttc atttgtttta
    49081 gaggaacatc gagatttgaa caccggctat atccccgaac gtgaaggaaa accgtatgct
    49141 aaacgttctc ttttatcctt gcgtggttta ttattctatc taaataaagg gatgacaatc
    49201 agttggctta tcacttttgg tttgatgggg gcggcatacg gctctatcta cgggaatatg
    49261 caacagtttt tagaaagtaa cgacttaatg aaacagatgt ttatccaatc tggcgtctca
    49321 attgaaaaaa actttacaag cacgatcatg gtagtcttga tttgtctagc tgctatttta
    49381 ccaattgcta gcatcaatcg tttatttaca gaagaaaccc acggacgtat gaatcagctg
    49441 ttcgcaacaa aaatttctag gaaccaactt tattggacca atatgttact agctattcta
    49501 tttgctatat tggcaatcct gattagttct ggtgcactag ggctttctgc tttggcttcg
    49561 atgaaggatg cgaaagacat ggatctattg atgtttctta aagccgggtt caatttcctg
    49621 cctgccgttt tagtgtttat cggaattagt ggctttctat tcggatggct tcctcgaatc
    49681 ggtaaacttg cttatatcta cttagcttac tcctttgcac tcaattactt tggcggaatt
    49741 ttggatttac cagaatggtt ttccaaaaca gctgtcccta gctgggttcc acggatgcca
    49801 aacgattctt ttgatctttc cgtgttcctt acgttatcat gtatcagcct tgcactgttc
    49861 gtccttggtt ctattggtta taggcgaaga gacttactag aaggataata aaaaagcatg
    49921 tacaatttca tgctagcctc caaatctggg tcaaaaatcc aacatttgga ggtcattttt
    49981 ttatttacaa gtcttctaac tgctctttat caatgatcca gacttctcga ttctttcttt
    50041 ttacataacc attctcctct aataatttaa attttctaga taaagtttcg ggggtcgtac
    50101 cgataaatgc agcaagttct ttcattttca ttggcaggaa aaagtgatcc ttccctgtcg
    50161 ctttagctaa gtcaagcaga tagacagcga ctcgttcttc tactttttcc atcatcaaaa
    50221 aagttgtctg ctgctgtact tttgttaatt tctcaacgtt gattgctaaa agtttcagac
    50281 taagggcggg ataatgcagt aagagttccg agaaatcttt ttgtctcaat atgcaaattt
    50341 ccgttttttc tagtgcttcg ccaaataaag actcatttgg aacgcctagc aactggctct
    50401 ctccctcata tccgcccggc tctattactc gtaaaagctg ttcctttccg ctagcagata
    50461 attgatacac tttcatactg ccggaggcca cgatcactaa ttgaggttct ccattcggcg
    50521 caagaatctg ttctcctttt tccacatagt gatgtttgac aagtgcgtgt actttttctt
    50581 gatcttgctg tactaagtga ttgaacaaag gaacaaatga aacacataaa tgatcatgac
    50641 tcataatctc tcctccttct aaacagctat ttctaataaa gaaacataac ttcccttatt
    50701 ccaactgata attttctttt atcatagcat aaacgtcaag cgaaccagat accagcaaat
    50761 agagtggatt tctttttgtc ccttgcttta ttttccttct tttgagacct taagtaattg
    50821 attcctatca attttttaaa tatttacttt ttgaataatc aaaaacaaac cttcactcgc
    50881 aagccgagag taaggtttgt ttttcgcatt gcttatttcg tgttgtctat tgaaattttt
    50941 ccgcacctag cttttgatat agtggtgcta gttcttgtaa ggtttcagcg gttatttgct
    51001 caacgtgttc gatttcttgc ggatagaaga atagtttacc catttgaaag gttcggtctc
    51061 tcatcgcttt tttcaactct tcttgtttct ttgtatcgga caaatagtca gacaaagcta
    51121 agtggtcgtc aagttcatgt tctggttgcg gccatatgta ataatccttg atatcgactg
    51181 ttttgctcca ctctttcagt atcgcaagca actggttata cgctgcaatg ctaccatatc
    51241 gttcttcgct tttataatgt tggtacatca aatagatttg gtattgtttt tgattcaaca
    51301 aaactgctag acaggcattc tcgtcttgac gagattcgct tcggtacgcg ctccaaaaat
    51361 gactgcgtaa attccagcca ttcgtccagc tttcgatttt aggtttgctc atgccgtaca
    51421 tatcaggcaa aagtgcagct gtctggagct gaatctcttt ccatttttgc cagtgttctt
    51481 tatattcttt cttgatttgt tcaatcttat ctgttggatg gctctctttg agctgtttga
    51541 atgcgtagat tggtcgatca aacaactgat aatctgattt tccaagttcc attgtttcgc
    51601 ctctttccgt tatcttttgt attctacctg aattttgcga tatggacaaa tagaggttgt
    51661 gaaaaagctg ttctgcatca agtcataaga acagccaaac aaaaaactgc gatgagcatc
    51721 accgcagttt tattgaactt aaggttgatt gatcacatct aaaagcgttg aaaataaaat
    51781 ggcactagaa gcagctcctg ggtcgatatg tccgattgca cgctctccta gataggaagc
    51841 tcgtcctttt ttagctacca agactttggt gtgttctttt gcctggtcaa tgatttcttt
    51901 tgttaaattc cctgccttca atgcctctgt gactggcagc caaacatcta acatcgtttt
    51961 atcgtcagct tctgcctttc ctcggctttg aatacccgct gttccctgct cgatcacttc
    52021 gcctaatttt tcttgagaat caatagaatc gacctctttt gtcgctttca tcatgttcat
    52081 gaatgcagat ccgtataacg gaccagaagc cccaccgact ttcgatatca tcgccataga
    52141 gaatactttg aatgtatcgc tgattgtttc aggatgatcg gcttgaaaag cttcttcata
    52201 agctgaaacc cctcttccca tgttatttcc atggtctcca tcgccaatcg gggtatctag
    52261 atcactgaga tattgtttgt tctgattgat tgcctctgca aattgcgtga gccattcttg
    52321 gatttcttga acggttagtt tcatattatc acccttttat cttgagattt tttaccatga
    52381 aatcgtctgt acattgcttt ctaaagaatc tttccattgt gtctccgtca agtcgatcag
    52441 tgttagagaa agaccttgca tatctagtga ggtcataaaa ttaccgactt ttcggaaaac
    52501 tacattgacg cctctttctt ccaacagagc taaaacatca ttcatgaaca cgaactgttc
    52561 catcaaaggc gtcccgccca ttccgttgac tagtacacct gcttcttttg gtaaattcga
    52621 gtaatcatct aaaatcttag taacaagttc ctttgccagt actttagaag gctgcatctt
    52681 ttctcgacga tagcctggct caccgtggat accaacacca tactcgatct catcttctcc
    52741 tagttcgaat cctggtttcc ctacttctgg tacagttgct gctcgaagcg ctagaccgat
    52801 cgtcttagtt gcctgtacga ccttttctcc cagttctttc aactcagcta gggaagcacc
    52861 gtttcttgct gcatcgccca cgattttgtg tacaaggaca gtacctgcaa ctccgcgttt
    52921 tccagcagta tacgtactat tttcaacggc gatatcatca tctacgatca cactttctac
    52981 ttcaatatcg tccatagcag ctaattcctt tgccatatcg aagttcaatg catcccctgt
    53041 ataattctta acgatcagca aaactccttt tccactatcg gcttccttaa tagccgtctg
    53101 aatctgatct ggagttggag aagtaaacac atcaccaagc accgctgcac ttaacatccc
    53161 ttcccctaca aacccggcat gggatggttc atgtccgctt cctccaccag aaaccaaacc
    53221 aacttgttcc gctttctgat tcttggctac aacacgggaa gattctacac gatgaacaag
    53281 ttctggatag ctttttacta atccttccag catttcttcg acaatattgc ttggatcatt
    53341 catgattttt ttcaatttat tcccatcctt tctttccggc attttgtgct tctgttaaga
    53401 tttgctgagt atcatctgtt ataccggcag tgatggctgc tgcaaaagct ccttccacta
    53461 aaggcgcatc caccagatga taacgttgct gctgctcttc ttccaacatg tcttttgcca
    53521 gttccgagtt caataccgcg ctaccgatat ccgcaaaaac aaaataacta gctgcatcgc
    53581 ttgattcatt gactgcttct acgattttca tcgggtctga tccgatctcg ccatttattc
    53641 cgccgagaga aaaaatttgc acctcttcgg atttttgcat ctgctcaatc atttctttaa
    53701 taccatctgt tactttttga ctatgagaaa taagcaaaat actttttttc acaagaatct
    53761 tcctttcttt tacatagttg ctaacgattg gtttcgcttt cattaatgaa caattcaagt
    53821 atataataaa tttctaattt tgggaaaata tgtgtagtgc ttcttgaagt ttgttatact
    53881 ttaattaaaa gagaggagtg atcgaatgat tacaacaaca acgaacagtg tagagggaaa
    53941 agccgtagta gcttataaag ggatcgtttt tggtgaggtc attactggga tccatgcatt
    54001 taaagacttg gaggcggggt tgcgaaatat ctttggcggc cgctcaaaaa gctatgaaaa
    54061 cgaactaatg ggtgcaagag aagaagcact tgccgaaatg gccgaacgtg caaaagcatt
    54121 aggagctgat gcgatcattg gcgtaaaaat ggactatgaa gtattaggca gcgacaatgg
    54181 catgctgatg gtcacatgta gtggaacagc tgtctccacg agataagtag gggacatctg
    54241 ttttaataac taaagagaga tgggacatgt agtggcactc aagaattaga tttttcagtc
    54301 taacttcgag gtactctacc ttcccatcct ctctttttta tttctttttg cggatgattc
    54361 cgtaagctgc tgcgactaac acacccgccc ctgctaagga ataactgaca gaagctgttt
    54421 tttcatttgt ttttggcaaa gtctgacttg ttgatttgga tggctctgtc gtttgctgaa
    54481 ctgtttctgt cgtgcttcca gaggtcactg atttttctcc tgccgaatgc aaaatatctt
    54541 ttattcgttg gaaactagct gctaagtcag ctttttttgc ttcaaaatca ttagcaactg
    54601 tttgtgcttc gctgatcttt ccgtggattg cttgactggc cgctgtgata tccgcttgag
    54661 tttgacttag ctttccagaa gctgtttgag caacctgatt taattgctga ttgaattctt
    54721 ttgcttgttg gatcttcccg tcaagatctg tttggacagc ttccgctttt gctttcgctt
    54781 cggcaagctt tttctcaagt tgtgcacggt catttcccac tttattttta agatcagcta
    54841 aatcttgatc gattgctgct tggtcttctt tcaatttgtt ttttgcagct tctaatgctt
    54901 cttcgagttc ttttctttta ttttccaagt cttgcaaatg atcgatttgg tcagaagagg
    54961 tagaactatt tattgatgta tcttctgaag atgaaatcgt ttctcctgaa ttatctgtcg
    55021 gtacattgga agtcatttct gtttccgagg caccgttttc agcaccagaa gagcttatgg
    55081 ttgttgaagg ttctgtttga gcaggttcag aagtttccgc aaaagctgtc tgtcccaata
    55141 agaaaatact ggaaacagca attggccaga ttaacggctt cattcttttt ttcatcactt
    55201 ttcccatcct tactactttt taactaattt cttattataa gcaaaaatgt ttggaagaac
    55261 cataaacaca acaggctgtt tgtctaaaaa acggtgcatc ttttattttt ttgtacgttc
    55321 cgggcttttc catgtcccgc ttccataacc taaaatcgtt ttgactgctg gaatgaaagt
    55381 cgtcacgatc gttatcgcgt tcactatcca gaacaaaagc atatatagtg gtgcgaaaag
    55441 aaggtatttc aattttcttc gtcgatcatc tacaatcagc gaagctagca actggaaaaa
    55501 tcctgcgacc atttcaaagc agatgaacac aaaactgaat gtaaaagtaa tataaatctg
    55561 ttcgtagttt ccttgatata cataatgccc gattaatcca gcaaaaagaa ctacggaaat
    55621 acaaaagaat attgaccaga caatactcaa tgtttgatca atgaagatga tcgttcttcc
    55681 aatatgttta aaaggatgga gcatcacttt tttgaaattc gtcagccaga cttctgttcc
    55741 accttttgcc caacgttttc tgtgtcgata tagcatcttc aacgtcacag gtacttccat
    55801 gaaaaagata atctcaggag caaaaacaga taaccagtca tttaactgat gatcccaagc
    55861 aatactgatg tcttctgtcg ctcgatcttg tctgaatccg cccacatcga tcaaggcttc
    55921 ttttcgatac atcgtatttg ctccactgta cgcataaaga ccaccgaaaa cagctgactg
    55981 tgttcgttta atgatgccca cgatacttga gaattcaacc gtttgagatt ttgcaatcaa
    56041 tttggtacga ttttggacat ccatatttgc agtgaccgca gcaatatgtc ttgcaccagg
    56101 gcgaatgaaa taattcacat acctaatcag tgcatctggc tccggtaccg tgtctgcatc
    56161 attgcttaaa atcaatttcc cttttgcaaa ggcaagtccg atattaaacg cgtgggcttt
    56221 tcctttattt ttttcgatcc gaaccacacg aagattagcg tattttttca tcagtctagc
    56281 taatatttct ggtgtttggt ccgttgaacc atcgtctgtc actaatacct catagttgtg
    56341 ataattcaat ttcgtcatca aatactcgat tgtatattcg atcacaattt cttcattatg
    56401 ggctggcacc atgatcgtga tgaacggttc gacactcaag ggaacatcta cccattcttt
    56461 ttgcttatgt ttgtataaaa acacataaca ccagacacca ataaaccata caaatccgcc
    56521 taaaatcgga taagaaacga gaaaaaaata cataatagac aaacaagtat ctaagaataa
    56581 attacctgta tgggtgattg agatcatttc agttccaccc cattttcttt atacaaatct
    56641 gcaatgaatg tcgtatctag atttttctct tcggagacag aataaaaacg gaccgtttct
    56701 ctctcttctt ttgttccaaa acgttccgta tacacttctt caagtaattc ttgtcttttt
    56761 ttcaattttt catcttcata ttcaaaagat ttatttactt ttttgtatag atttcgattg
    56821 ttccacctag tcaatacaaa tgaggtaatc aggaaactga aaaaaatcaa tacaaaaaag
    56881 ccgattaaga aatacagcat tttcttttct gataaaaaag cgtacaagga aaaatccttg
    56941 gctctttctg gtctcgttaa tgggaaaaag acccatataa aaggaagaac aacgatcatc
    57001 catcctaaaa gagccactaa cgtttgccaa atctttaacc agtaattacc ttttgaaaaa
    57061 tacttatctt tcaccaaaat tgatgcaact tcttctcttg ttactttttt catatcctca
    57121 cctcacgttt ttttgttacg acgtaggagt ttaccataca tttcatttct tttcacataa
    57181 agtgttccta aatttttcct aagaaaaaga acaaaacatt tctcatcagc aaatgaaaaa
    57241 tattttgttc tttttatcag ttgttctttt tattttttat ctcttaatta tgttgctctt
    57301 tccaatacga caatgctttt cattcctcta gatatcgccg tgtacatttg tctgcgtctt
    57361 ctttgctcat ctccatcgtt ttcaaatgga tataagatta catgatcaaa ttccagtcct
    57421 tttgctagac tcaaaggaat gatttggcag ttttctaatc catatgaatt ttttttaatc
    57481 gattcttgta gcgtttgggt ttcctcttct gtttgggtga taactgccgc tttttctcct
    57541 tttagagaaa ccaaaatctc agctagtatt ttcaacaatt cttcagagga tcgaaaagag
    57601 cggtattcgg gttcttttcc ttgcggtcgg atcgatacga tgtcgatctt ctcttgatcc
    57661 acagcatagg ttttgaaaag ctctgtgatt gctccgctag aacggtaact atttctaaga
    57721 tcataccgat ggatcggcag atggtagtcg tcgaaacaac gcataatatc agcaaaagta
    57781 gtggaagaat taaagattgc ctgattctcg tcacctacta aagtaaagtg agtttttgga
    57841 aataattcga tcaatagacc taattgtgcc agggtataat cttgtacttc atcaatcaat
    57901 agatagcgaa atgctggtac atttaccttt tcaacaagta aatgacgaat agctaatata
    57961 atgactgctt catcaacagt acgtgtgggt tgccaagcat aagctgagcc atatcgtttt
    58021 tcataaattc tttcaaacaa ctgatgctca tccacccatg ccatttcttc gatttgtctg
    58081 gttatttttc gatatttttt ttgtaaaagt ttccttgcat aagctacaat actttgttcc
    58141 gaatcatcag aaatcaattt accgaataat tccaactgcc tatcttctgt caacgagagt
    58201 acctgattct gcacagcagg actttttgct tgtttcaaaa gatgattctt ccattcgctc
    58261 atcagtgcct ttttcgttgc ttgaagccta tcgatcaatt taggatgagc aggaactttc
    58321 tcatatattt tttcgatcgt ttttttagaa aggactgttt ttccattttt agtaagtcca
    58381 cggataaaat tcggatgatc taaaaacaaa ggatctgatt gttttagatt atcgataaac
    58441 tttttgctac gcaaacgttc tgtctgctcc gatacatttt ctcccgtgat acgtttgaaa
    58501 taagcctctt caccttctat ttcctctgct gaaagctgtg aaaccagctg tatgatggtt
    58561 agattcagtg gatttctttc acctaatgat ggtaggacat tcgaaatata gtcgataaac
    58621 cgatgattag gtgatagaat cagcaagtca tcggatgtca tcgtatctcg atataaatag
    58681 agcagatacg caatacgctg catgatagca gaggttttac cacttcctgc tacgccattt
    58741 accaagatat tttgactttt cacatcccga atgattgtgt tttgttccga ttggatcgta
    58801 gcagtgatag ccttcatttc attggtctca tcttggccta agacttctaa taatacgtca
    58861 tcttgaatag ctacagacgt atcaaaaaac ttgaccaaac gatctctttc caaaagaaat
    58921 tgtcgtcttt ctttaataac cgtatcgatt ttattttgac gaaccgtata agaagatgga
    58981 ccaatcatgt tattgtaaaa aagttcggca attggtgaac gccaatcata aacaagattt
    59041 tcatctgcat catctgtgaa atttgctgta ccgatataaa aggattcttt tggctcatta
    59101 tccagaaagt ctacaacgac ttttccaaag tagggacttt tcaataaacg ttcgatcttt
    59161 gctagctgat tttctgcgtt tttctgtttg atattcatct gatcgatttc tctatttttc
    59221 atttcaatca tcgaaaaagt atccaggtta tctaagtaac tgtcaaaatt caatcgaagc
    59281 tcgccagcca tttctttcaa cgactggttt ccttctattt ttgccgtatc catcgattcc
    59341 cgcagttcgt tttttttatc aattagcttt tgatacacgt tcttcagata tgcttcttct
    59401 aactgttttt gtgtgttgac catacacatt ctcctctttt tttaaagtgg tggaaccgat
    59461 tagtttacct cttttaagag tcgaatgcaa gctttttaac gagtatcatt tgttaggata
    59521 tatcagttct tcaggtcgga cagtttgata taaagaaaat gcaccatcaa ggttttttac
    59581 gtggtagcca gactgcttca agattctttc cgctagatag ctacgtaatc cgctatgaca
    59641 gctgacgata tattcttgtt ggctgtctaa ttcatttaat cggtcccgaa gttcattcaa
    59701 agggatatgt ttggcttcct tgaatttgcc cttttccaat tcttctgctg ttcgcacatc
    59761 taataaaatt tttccttttg ctagttctgt cggcaattca tgccattgta cggtttcact
    59821 aagcccttct gcaatgttca ttgctgcata tcctagcatg tttactggat ctttggctga
    59881 gccaaatggc ggtgcatacg tcaattctaa ttccggtaaa tcgaagatcg tcaaatgccc
    59941 tttgattgct gttgctaaaa tatcgatccg tttatccaca ccttttgccc caacaccttg
    60001 tgcaccataa atctcgccag tctctggatg gaagatcaac ttcagtaaaa tatctgttgc
    60061 ttctggataa tagcttgcat gatcttttcc tgatacatga atgacttcaa aagacagttc
    60121 gttttctttg gctgttcttt cacttaaacc ggtggatgcg gcagtcattc caaacgttcg
    60181 tataattgct gttccaatac cgccttgatt tcttcgagaa attccggaaa tcgtgtccgc
    60241 aacttgtcta ccttgacgat tggctggtga agcaagagaa ataagtgcat cttttccagt
    60301 gatttgctgt tttacaacga tagcatcccc caccgcataa atatcaggaa tattcgtttg
    60361 ataacgttcg tctactagga tacccccgcg tatgcctaat tcgattccag cggtcactgc
    60421 tagctggtta tcaggacgaa caccaatgga taaaataact aaatcagcag ggatggtacg
    60481 cccatcatcc agtcgcaatc gtttcccgtg gtcttcaaat ccagcgacag catgagaagt
    60541 aatcacttct actccttgat gagacaattc tttttctata aaagctgcca tttcttcatc
    60601 cagtgttgga agaatatgtg gtgcttgttc gatcaccatg acttctaaac ctcttctttt
    60661 taggttttct gccatttcca atccgatgaa tcctgcacca acgatcacgg cacgctttgg
    60721 ctgtttttct aatgcatgca tcactttatc gatatctggt acatttctaa tagaaaaaac
    60781 attgtcggct tctgttatcc ctggaatcga tggaacaact ggttttgcac caggagataa
    60841 aaccaatgca tcgtactgtt caatgtgttt ttgaccctca tgtacgactt ctaccgtttt
    60901 gttttcggga aagatggctg tcacttcatg atttggacgc acatctaaac aaaaacgagc
    60961 ggataatgat tctggcgttt ggacaagaag attttcccgt tcactgattt ctcccgaaag
    61021 ataataaggc aagccgcaat ttgcaaaaga aacatacggt cctttttcaa aaacaacgat
    61081 ttctgcatct tccattaatc ggcgaagccg tgtagcagca gacattccac ctgctacacc
    61141 tccgacaata acgattttca tcttatttcc ctcctactgt tcgatcaaac cattgattca
    61201 tgccaccacg tacattcact acatcataac cagatttctt taattcttta gctgcttgtt
    61261 tactcctcat ccctgattga caaatcacat agacggtctt ttctttgtct ccatcatatc
    61321 tgtttatact ttgtaatgga acatttttag ctccttttat atgcccgccc cggtattctg
    61381 caggtgttct aacatcaagt aacgctggat tttccaaaag cttttccttt aattctggga
    61441 ctgttatcga ttttattgat tgaaatagca aattcatttt ctgcacctca tttacatttt
    61501 tataaatacc tcatggggta tattaaacag gagctttatt aatatgtcaa ccagaatgac
    61561 tcttcatttt tttcactact ttttatattt gcataaaata ccgataaggg gtattatcta
    61621 attataaaaa tagaggagaa tgtgttatgg agattgataa taaaaatatc ctgaaccgtt
    61681 tgaaacgtac agagggacaa attcgtggta tccaaaaaat gatcgaagac gaaaaagaat
    61741 gtatggatgt catcactcaa ttaagcgctg ttcgttctag tattgatcgc gtaatgggca
    61801 tgatcgttgc agataatctg aaaaattgct ttgagaaacc tgatagtaat ccagaagaac
    61861 aagcggctaa actagaacaa gcgatcaaga tgattattaa aaagtaaagg aatgatttca
    61921 atgaaagtcg ttttccatat tgatgaatta gaaaaatggt cagaaacagg gaaaaacgta
    61981 aaaaacctga taaaagcttc tccagaaacg acgattgtcg tatctgtaaa tggcatcgcg
    62041 attaccggtt atctagactc tgccaatgca gaattcttag atttgcaagg agtcgttttt
    62101 cacgcttgcg ccaatgctat gcgtgctaat catatttcag aaagttcttt acctgaacaa
    62161 gtaatcgttg taccagcagg tgtccttgat ttagttgaac tgcaatccca aggttatgct
    62221 tatatcaagc cttagtcagt agaggttgcg acagaagtga tcagcttcaa gaaatttcgg
    62281 cttatttttc gaagaagcta cttctggaaa accgtgaatc aaaggttgtg aaaacgctgt
    62341 cctgcatcaa gtaataagaa cagccaaaca aaaatagctt ctcatatttt tcgtttggtt
    62401 gggcttatta ccgcagatgc aagcttttga acaccgttta aggaagaggt tgtgaaatca
    62461 gcggtttgac ctaagtatta gagaaaaaaa cgggaaaata gctcctcata ttttgccgtt
    62521 ttttgagcta ataccgaagg tcagctgatt gaacaccgtt taaggaagag attgtgaaaa
    62581 agtcgcttag tttcgagtat taagaaaaat tttgtgaaaa tggatttcta catttttgca
    62641 taaatttggc ttaataccga gaaactggct tttgaatacc gtttaaggaa gaggttgtaa
    62701 aatcagcggt ttgacctgag tattagagaa acaaacggaa aaatagctgc tcatattttg
    62761 ccgttttttg agctaatacc gaaggtcagc tgattgaaca ccgtttacca agaggttgtg
    62821 agcctaccat ttaactccga atcacaagaa ataatttcaa aaacaacttc tcctgttttt
    62881 ggttcggttg gcttattatc gagaagtagc tactgggagt ctatttatca aaaaaaggaa
    62941 tgcgacatag gtcacacccc ttttttattt tctttgaaac atctttcggt actcgacagc
    63001 atacaagaca aaagattgta aaagaccgta agtgatgacg gcaaaaatga ctctcaccca
    63061 cagcgttggt aattctggga aaagcagcaa aaggatcatg ccaacataga tgacagcagt
    63121 cgctactttg ccataccact tcgctccact taatttgata tttttagata gcccgattaa
    63181 tccagctaca aacataaagc cttcttttat caagaataga ccaaacaaca gccaaagcca
    63241 cggtcgatac catgccatag acaaaatcag aaaaagttgt gtcaatttat ctgcaaacgg
    63301 atcaagcacc ttccctaagt ctgttacctg attatatctc cgagcaatga ccccgtctag
    63361 ataatcagac aaacctgaga caacaatgac cgctcctgct atataaaatg actgtctcag
    63421 cacaaaataa agataaatcg gcagcaaaaa aatacggaat atcgataaaa gattcggaat
    63481 cgtttgtatt tctttacgcc agtctgtgct taatttcatt ttatcgccct acctcctcag
    63541 cactcttttc tttttatttt agcttacacg gggaataaaa ccaatgattt cactgttttt
    63601 atttttcttt acagacactg atattatgag ctaatttgag ataatcactt gctgttttca
    63661 tcgtttactc ttctttcttc ctgtcgtttg cgcatttctt ttactagtac tttatgagct
    63721 ttttttgatc ctcgctctag gtcacgctgc cgtttacgtg ttttataatc gataaacaga
    63781 ctgtctaaat cgtaacctgt cgggtacaga tcttctgctg aacgcaccag acgaacacgc
    63841 tgacgaggca cgtggattat ttttttgtct aaatatacat caatcgtatc ttcacctata
    63901 tcttcataaa ctaacgcttc tttttggtat tcattgacaa atatccgatc accttttgca
    63961 aagagctgac gttctttttt attctccttc ctatttgtaa ctgctgtctt aggaagaaat
    64021 tcttttttct gtgtccgata ggctttttcc gccaagtaac gctctgcttg atggatcaat
    64081 ttcatcgaca tatccatttt atgagcaatc cacaaagctt ggctttctcc tgtttcttcc
    64141 aacccgcaac tgatatttag gacgaagtgc ttcccgatcg aaagccatag cagccggcac
    64201 aaaatcttca tgatctccgg cgaatttctt gatttctcca taatgggtcg tggcaatgat
    64261 caatgcccct tgctcataca tagattccat gattgcgatc gctagtgcag ccccttcatt
    64321 tggctctgtt ccactgccaa tctcatctaa aagtaccaac gtattccttt ttatcttttt
    64381 caaaatagca gcgatgtttt gcatatgacc agaaaatgta ctcaacgcat tttctaaatt
    64441 ttggtggtca ccgacatcga cgaaaatctc atcaaagaca gcaagctctg tcccttcttt
    64501 tgccggaact tgcataccga acatcgccat caaagtcaat aaaccgactg tcttcaacac
    64561 gactgttttg cctccggcat ttgctccggt gataatcaag cctcgatagt ctttaccgat
    64621 ttcaacatcc aatggtaccg catgctcagg taaaaatgga tgtctgcctt gcttgataat
    64681 gatatgttcc gatttattga ttctaggtgt gcttccattg atttctcggc taaattttgc
    64741 ccgagcaaag atgatatcta acaccgtgat cgtttcgatc aataaatcga tcacttcttc
    64801 gttttctgcg atagcaccag tcaatgccgc caggacttga tattcttcac tgatttcttc
    64861 agcttttaac aactgatagt gttcattcaa tttagaaatc acagttggtt caataaaaac
    64921 cgtcgttctt ttatttgatt catcgataat cgttccatct attttatttt tatagctggc
    64981 tttgatagga atcgtatagt attcgccttt ttgaacaatc attgcttctt ggatcatttc
    65041 tttgtttttc ggatgacgca agaatttcag taattttgac tggatttctt tttcgattag
    65101 ttgtaattgt ttgcgtactt tacgcaaatt acgtgacgcg tcgtcactga ctttattatt
    65161 ttttattttc tggtcaatca actcttctac atttatcaaa tcaggaagat gtttgctata
    65221 agcaaacaac aagggtgtct ggtattgatt cttatcaaaa aactttgtga tcatccgact
    65281 gcttctaaga aaatccgcat attcgatcaa atcggttggc tgcagaatca accctttttt
    65341 gacttgttct gtcagtgcat cgatcctcgg caaccccata aatggaacat gctgactgct
    65401 ttctaagatc aagcgtgctt ctcttgtttc ttcttgacga tccaagacag tttgtaggtt
    65461 tgtcgagacc gtcatatcgc tgattcgttt tttgctatag tttccaattg ctcttgcttg
    65521 gatttccttt ttgatccgat caaattgtaa ttgactaatc atttcgttgt ccatattctc
    65581 tccttttctt gaagagatac ctgtcccaaa ataaataagg gcctagagat aaataaaagg
    65641 atagaacaca gcttaaaaaa gt
//
LOCUS       DAPBAF010000011        60657 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.011, whole genome shotgun sequence.
ACCESSION   DAPBAF010000011 DAPBAF010000000
VERSION     DAPBAF010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 60657)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 60657)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..60657
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.011"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(38..1189)
                     /locus_tag="RD451_000814"
     CDS             complement(38..1189)
                     /locus_tag="RD451_000814"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HDT7566097.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(1202..1639)
                     /locus_tag="RD451_000815"
     CDS             complement(1202..1639)
                     /locus_tag="RD451_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDT7566098.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            complement(1654..3420)
                     /locus_tag="RD451_000816"
     CDS             complement(1654..3420)
                     /locus_tag="RD451_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HDT7566099.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEALATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            3684..4361
                     /locus_tag="RD451_000817"
     CDS             3684..4361
                     /locus_tag="RD451_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7566100.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            4364..5491
                     /locus_tag="RD451_000818"
     CDS             4364..5491
                     /locus_tag="RD451_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7566101.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLPLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLPDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(5691..6131)
                     /locus_tag="RD451_000819"
     CDS             complement(5691..6131)
                     /locus_tag="RD451_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDT7566102.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAKTIEEVQMIFEHGHI"
     gene            complement(6142..8175)
                     /locus_tag="RD451_000820"
     CDS             complement(6142..8175)
                     /locus_tag="RD451_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HDT7566103.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            complement(8177..9880)
                     /locus_tag="RD451_000821"
     CDS             complement(8177..9880)
                     /locus_tag="RD451_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDT7566104.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKKSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            complement(9974..10924)
                     /gene="manA"
                     /locus_tag="RD451_000822"
     CDS             complement(9974..10924)
                     /gene="manA"
                     /locus_tag="RD451_000822"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HDT7566105.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIATEPGK"
     gene            complement(10963..11988)
                     /locus_tag="RD451_000823"
     CDS             complement(10963..11988)
                     /locus_tag="RD451_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HDT7566106.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKTVLPK"
     gene            complement(12197..13066)
                     /locus_tag="RD451_000824"
     CDS             complement(12197..13066)
                     /locus_tag="RD451_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extradiol dioxygenase"
                     /protein_id="HDT7566107.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            complement(13525..15417)
                     /locus_tag="RD451_000825"
     CDS             complement(13525..15417)
                     /locus_tag="RD451_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7566108.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            complement(15414..17141)
                     /locus_tag="RD451_000826"
     CDS             complement(15414..17141)
                     /locus_tag="RD451_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7566109.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            complement(17157..17807)
                     /locus_tag="RD451_000827"
     CDS             complement(17157..17807)
                     /locus_tag="RD451_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HDT7566110.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            18011..18307
                     /locus_tag="RD451_000828"
     CDS             18011..18307
                     /locus_tag="RD451_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HDT7566111.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            18479..19099
                     /locus_tag="RD451_000829"
     CDS             18479..19099
                     /locus_tag="RD451_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HDT7566112.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(19191..20357)
                     /locus_tag="RD451_000830"
     CDS             complement(19191..20357)
                     /locus_tag="RD451_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDT7566113.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(20369..20722)
                     /locus_tag="RD451_000831"
     CDS             complement(20369..20722)
                     /locus_tag="RD451_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HDT7566114.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLETVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            20850..21872
                     /locus_tag="RD451_000832"
     CDS             20850..21872
                     /locus_tag="RD451_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HDT7566115.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            21891..22052
                     /locus_tag="RD451_000833"
     CDS             21891..22052
                     /locus_tag="RD451_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566116.1"
                     /translation="MNQQDVLDRLREELNIPFFDGKIEDKEYSEEEYQKLKADLQNYF
                     EQYVQNVEN"
     gene            complement(22311..22745)
                     /locus_tag="RD451_000834"
     CDS             complement(22311..22745)
                     /locus_tag="RD451_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566117.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLKKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(22855..24714)
                     /locus_tag="RD451_000835"
     CDS             complement(22855..24714)
                     /locus_tag="RD451_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HDT7566118.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            complement(24832..25992)
                     /locus_tag="RD451_000836"
     CDS             complement(24832..25992)
                     /locus_tag="RD451_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-3-phosphoglycerate dehydrogenase"
                     /protein_id="HDT7566119.1"
                     /translation="MYHVHLIDAIPEQEIEKLQGEYFKIIDDLPAEGIVIRSTKVKDE
                     WLTPDLLAISRAGVGVNTINVEKASENGTIVMNTPGVNANAVKELVLCCLLLSSRPII
                     EASRMVQTLTGPNILEQAENKRSAYVGRELQGKTIGLLGLGAIGTKVALSCYSLGMDV
                     LGYSIRDAQLDYVRQADLETVLSTSDYIVVMLPLTEDTKGLIDQANIEKMKKDAVLIN
                     VGRSEIVDKYAVMQALEKQHLAKYLTDFPEEEFLENDRILMLPHLGGSTQEALADSGR
                     LAVEALKDYLLFGTVREAVNYPSARMFFQAPFRFTIFYQKKTNILAEIFSLLNENELA
                     IADISRNHKNEHVYILIDIDSTDFEQLNQVKQQLEKISGVRKVRLLKKPERP"
     gene            complement(26299..27723)
                     /gene="araA"
                     /locus_tag="RD451_000837"
     CDS             complement(26299..27723)
                     /gene="araA"
                     /locus_tag="RD451_000837"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HDT7566120.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(27739..28437)
                     /locus_tag="RD451_000838"
     CDS             complement(27739..28437)
                     /locus_tag="RD451_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HDT7566121.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(28394..30055)
                     /locus_tag="RD451_000839"
     CDS             complement(28394..30055)
                     /locus_tag="RD451_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HDT7566122.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKR
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            30273..31673
                     /locus_tag="RD451_000840"
     CDS             30273..31673
                     /locus_tag="RD451_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HDT7566123.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKVLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIIGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(31925..33004)
                     /locus_tag="RD451_000841"
     CDS             complement(31925..33004)
                     /locus_tag="RD451_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDT7566124.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(33090..34049)
                     /locus_tag="RD451_000842"
     CDS             complement(33090..34049)
                     /locus_tag="RD451_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HDT7566125.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(34061..35572)
                     /locus_tag="RD451_000843"
     CDS             complement(34061..35572)
                     /locus_tag="RD451_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HDT7566126.1"
                     /translation="MKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHETADG
                     DGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIEPNSF
                     GLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQKKPF
                     GVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPRLPSY
                     PEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFDRQIE
                     EIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMEDTLLF
                     GSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAKGQVL
                     KQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLLDQGE
                     HYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(35594..36157)
                     /locus_tag="RD451_000844"
     CDS             complement(35594..36157)
                     /locus_tag="RD451_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HDT7566127.1"
                     /translation="MKIVETKFYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            complement(36163..37026)
                     /locus_tag="RD451_000845"
     CDS             complement(36163..37026)
                     /locus_tag="RD451_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDT7566128.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(37040..37936)
                     /locus_tag="RD451_000846"
     CDS             complement(37040..37936)
                     /locus_tag="RD451_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDT7566129.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(38111..39400)
                     /locus_tag="RD451_000847"
     CDS             complement(38111..39400)
                     /locus_tag="RD451_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDT7566130.1"
                     /translation="MKEEQKMKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTL
                     TFWNGFTASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFI
                     ALNYPDFAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMY
                     MYWNNDLFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLA
                     NGGKLVNDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIE
                     INGPWLNNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFL
                     KYWNTTEIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQIS
                     AINNDIINPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(39372..40889)
                     /locus_tag="RD451_000848"
     CDS             complement(39372..40889)
                     /locus_tag="RD451_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HDT7566131.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            41087..41977
                     /locus_tag="RD451_000849"
     CDS             41087..41977
                     /locus_tag="RD451_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HDT7566132.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(42050..42874)
                     /gene="nadE"
                     /locus_tag="RD451_000850"
     CDS             complement(42050..42874)
                     /gene="nadE"
                     /locus_tag="RD451_000850"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HDT7566133.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(42886..44358)
                     /locus_tag="RD451_000851"
     CDS             complement(42886..44358)
                     /locus_tag="RD451_000851"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HDT7566134.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(44995..45357)
                     /locus_tag="RD451_000852"
     CDS             complement(44995..45357)
                     /locus_tag="RD451_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HDT7566135.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            45580..46332
                     /locus_tag="RD451_000853"
     CDS             45580..46332
                     /locus_tag="RD451_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDT7566136.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWLSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(46472..47395)
                     /locus_tag="RD451_000854"
     CDS             complement(46472..47395)
                     /locus_tag="RD451_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDT7566137.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYQKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(47410..47682)
                     /locus_tag="RD451_000855"
     CDS             complement(47410..47682)
                     /locus_tag="RD451_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566138.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
     gene            complement(48152..49777)
                     /gene="groL"
                     /locus_tag="RD451_000856"
     CDS             complement(48152..49777)
                     /gene="groL"
                     /locus_tag="RD451_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HDT7566139.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDATIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
     gene            complement(49828..50112)
                     /gene="groES"
                     /locus_tag="RD451_000857"
     CDS             complement(49828..50112)
                     /gene="groES"
                     /locus_tag="RD451_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HDT7566140.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            50337..50999
                     /locus_tag="RD451_000858"
     CDS             50337..50999
                     /locus_tag="RD451_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDT7566141.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            complement(51075..52367)
                     /locus_tag="RD451_000859"
     CDS             complement(51075..52367)
                     /locus_tag="RD451_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDT7566142.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQHLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            52537..53166
                     /locus_tag="RD451_000860"
     CDS             52537..53166
                     /locus_tag="RD451_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HDT7566143.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAASDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            complement(53269..54078)
                     /locus_tag="RD451_000861"
     CDS             complement(53269..54078)
                     /locus_tag="RD451_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDT7566144.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(54133..55002)
                     /locus_tag="RD451_000862"
     CDS             complement(54133..55002)
                     /locus_tag="RD451_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system regulatory protein YycI"
                     /protein_id="HDT7566145.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            complement(55003..56319)
                     /locus_tag="RD451_000863"
     CDS             complement(55003..56319)
                     /locus_tag="RD451_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566146.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            complement(56316..58151)
                     /gene="walK"
                     /locus_tag="RD451_000864"
     CDS             complement(56316..58151)
                     /gene="walK"
                     /locus_tag="RD451_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HDT7566147.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVILSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            complement(58156..58860)
                     /locus_tag="RD451_000865"
     CDS             complement(58156..58860)
                     /locus_tag="RD451_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7566148.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            complement(59050..59910)
                     /locus_tag="RD451_000866"
     CDS             complement(59050..59910)
                     /locus_tag="RD451_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HDT7566149.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITPEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            complement(59897..60466)
                     /locus_tag="RD451_000867"
     CDS             complement(59897..60466)
                     /locus_tag="RD451_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HDT7566150.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
BASE COUNT        17515 a        12719 c        10452 g        19971 t
ORIGIN      
        1 aaaaatttcg tcacattccc ctttttcgta tcctatttta agcgacttgc ttggcataac
       61 ggttcacgtt ttgcttgata ttcccgattg ttttcggatc attgattcct gtgacttctt
      121 gaatcaattg ttccaagttt tcatggatct tcatttcatg caattgacgg ctttgttcat
      181 cttcaggatc atagtaatta aaaataatcc ccattgttgc cgtcaaatgt gggcaagtca
      241 agttatgttc ttgtagttct ctcactggac gtgtaaatct ttcttgataa cctaacttac
      301 gtaatggtgt ccgagcgaca cgtgtgatcg catcagagat atttttgttt tggaagcgat
      361 gaatgatttt ttcaatatac gcatgatgct gctctgcatc aaacccccat ttggcaatca
      421 gcaaacttcc tgtttcctgc aaaactgatt ttaattgtgc cacaactaac gcatcttgca
      481 ttgcttcatc aatggtctgg taacctaaca aggcacctgt ataagcgaca gtcgcatgac
      541 cagtattgac actaaatagt ttgcgttcga tatatggttc tagatcatct acatataaaa
      601 ccccttttaa ttggattttt ttattttttc tttggctatc gtcaatgacc cattctttga
      661 aaggttccac ttggacgaat aaaggatctt catggtgttg taatgggacg attcgatcga
      721 ctgctgcatt tggaaagccg atatatttgt cagtaaatga tgtttccgga agatatttat
      781 acacttcttt ttctagaaat gctgaaccgc caatcatatt ttcacaggca atgatatcta
      841 aagatgttgt gcttccttcc ttttctcttt cttggatacc ttttgcaatc aactcagcaa
      901 taaaaggtaa gatattcggg ccaatggcgg tagtaactaa atctgcttca gcgatttctt
      961 ggattacttt ttctggattt gtttgattgt tgattccttt gacatttttt acagtgattt
     1021 tttcttttga ttcatctgct aattcgattt cgtattcttt tctttcattt aaagcatcaa
     1081 tgatcgtgtg attcacatct acgaaagtaa tctcaaatcc attagctgcc aaaacctctc
     1141 caataaatcc tcgaccgata tttcctgcac caaaatgtac tgctctcatt tttctctctc
     1201 cttaagcaat tgctagattt tccgttactt cttctttgct gagcgcgtct gctagctgga
     1261 caacattgtc catatcactg caataaagtg cgatttgctg tacaagttgc aaatgctcat
     1321 ctccgactcc tgcaataccg aacaaaacag tcgcaatctt ttcttcttct tcggtaccaa
     1381 aatctacacc atctggtact tgaacgacac agatgccgga ttttttcaca tatttttttg
     1441 cttcatctgt tccatgagga atcgcgataa aattccccat ataaacagat aacattttgt
     1501 ctctatctac catggcatcg atatattcct catcaacgca ccctgcttct acaagcatct
     1561 gaccgcaata gcggatcgct tcttctttgg ttttaaaaga tcgattgagc tcgatcatgt
     1621 cgaatggcaa actttgcatg ctgttttcct cccttaagct gtctgtttca aatattgtgc
     1681 aatcgattcg tatttttgcg gattgaccat gctgttgact gataaatgaa tggattgagg
     1741 tgcagccatc tgtacttttt ccgctaaact ttctttggct acgatcagtg aatcaggttc
     1801 atcttttaaa tcttggatat tgacttttct taacgggata gttaaatggt tcttgtctaa
     1861 tatatctttg agcacggtca tccccattgt tgctgatccg gaacgatcat cgtggacaag
     1921 tagaatctct ttgatttgtt tgatgtttgc tgaaagaaac tcttctgctg gctcattctc
     1981 aatttcagaa actgatgttt tctgcttgct gcttaattct tgaatgattt catcatatcg
     2041 aggtgaattc aaaaagtttt ctactgagac aaaacgcgcg ctcggtgctt tttgttttgc
     2101 tctttcttgt agttcgacct gagtaacgat caatgtattc gagtcatctg tcagttggct
     2161 gattgcttga ttggtcaccg tttgaggcaa gtctgcttcc tgtacttttt ttctcaagat
     2221 cgaagcgccc atcgcacttg atcccattcc tgcatcacaa gcaaaaatga ttttttgtac
     2281 gccagagaat gtagctcctt gaggaatacc ttgggcacct ttggaagctt gcttagctgc
     2341 ctttgtctct tgaacagatt tttcgaagtc ttcatttgta tctttcgcat ccgctttcaa
     2401 aattactgca gaaataccaa acgaaacagc tgcggcaaca atcacgccca aaataacagg
     2461 aaggtaagaa ttgaacggtg tcatcgctag aatcgcaatg atcgaccctg gagaagctgg
     2521 cgctcttagt ccagcatcca tcaattggaa aatgaaactt cctgacattc ctccgcctat
     2581 aactgataag aataataacg gtttcatcat aacgtaagga aaatagattt catggatccc
     2641 gcctaaaaag tgaatgatca tggctcctgg tgctgaagat tttgctgctc ctttgccaaa
     2701 caaagtaaaa gcaagtaata cgccaagtcc tggaccagga tttgcttcaa gcaagaatag
     2761 aatagatttt ccagcctctg ctacttgttc agttcccaat ggtgtcaaaa tcccatgatt
     2821 gattgcatta ttcaaaaata agatttttgc tggttcaata aaaatacttg tcaatggaat
     2881 caaatgggca gataaaatga tctctacacc ttttgccatt gcttgagtca atgcatcgac
     2941 aactggacca atcgcagaaa aacctaataa cgctaatcca aaaccgataa gacctgctga
     3001 aaaattattg actagcattt caaaaccgga tttgatccgt ttttggaata gctgatcaaa
     3061 tttcttgatg gcatatccac caagaggtcc catgatcatc gcgcctagca tcattggaat
     3121 atctgttccg acaatcacac ccatcgttgc aattgcccca acaactgatc cgcggtcacc
     3181 agcaattact tttccgccag tataaccgat caataaagga atcagataag ttagcattgg
     3241 gcttaccatg gtagccaaag cctcatttgg taaataacca tctgggataa atagagccgt
     3301 taatacaccc caggcaatca gtgctccaat atttggcatg accatgcttg ataaagtact
     3361 gcctaatttt tgtaccctcg cttttagcga aatgttgttt ttgggaatcg tccgttccat
     3421 tttgtctctc cctctctcct tttgatactc taattgtatc cgcttactaa aaagagaaat
     3481 agtcgtactt tggcacgaaa ctttgtgcca aaggtttgag tatgtcagca aaataaaaag
     3541 atttcggtat cagaaaactt caattttaaa taaaactgtt attttaattt ttttataata
     3601 tgcaaacaat aacttttgtt agcatttaat ttagatgttt tccattctat tatgttatta
     3661 aattttatat tggaggccta tctatgacat tactgatcaa aaacatgaac atgaaacgtg
     3721 gtaaaaaacg tgtgattcga caattgaatc ttttagtaga atcaggagaa gtagctgctt
     3781 tgattgcccc gaacggattt ggcaaaacaa ctttgctgaa tggcattgcc caactgctgc
     3841 caacaactta tgatcaattg tcccttcaca acatctctcc tactgcttat acagattatc
     3901 gccggtcttt cttttttcta gaatcaacga atcagttatc cgactatcta tcggctgttg
     3961 attatttgac tttgatcaaa tactattggc agagcaaagt agaatgccaa actgttttcc
     4021 aacgattgaa gatgactgag taccttactt tgccgattgg aaaaatgtct ctaggaatga
     4081 aacaacatgt cttgcttgct gcttacttga tcagtgattc atctgtcatg ttattcgatg
     4141 aaccgttgaa cggattagac ccaggaagta ttgatatctt gaatagcctc atcagacaat
     4201 ggcagaaaga ggggaagacg attcttcttt cttcccacgc tatcgcgaat atccaatcga
     4261 tttgttctaa agcatgtttt ctaaaaaatg gagaaatcgt cacagaatcc tcaaatatgg
     4321 aagagatttt agctatttat cgtaaattat atgaggtgta actatgtctt tacttacatt
     4381 tgaacgcaat ctcttactaa aaaacaaagt aaacttttta tttcctctat tgttggtcgt
     4441 gctctttgca ttcccacttt tttttgatca taaacttgct tatacagaat tcgatgaact
     4501 gaatcataac tatgaagaga tgcaacgttt gattgaaacg ttgaaagaag atgagaatga
     4561 gaaagaattt gtggaaagtt tagagaaaag caacaaactg atcgaagcaa tcttacatgc
     4621 aaaaaacaca gggaatgtcc agcaaatggt cgaagcaact tatcattatg aaaaagatat
     4681 actggatcga ctgatttctg gtcaaagaca aggaattcca atcattgaac aacaaaaacg
     4741 tgtcgagttg ctccgttata tgaaagaaca tcagatccaa agatattcta tttttgactt
     4801 gccagcgcat ctccctttag caaattacta cgaaaatatt ttttcaggaa tgatttctag
     4861 ttttttgatt ttatgtataa ccgccttgtt tctttcttcc atcatctctt atgaaaaaag
     4921 aaagcaggta atctctctag tcaatctatt accggatagt atggtaaaga aacatagcat
     4981 ccgttttacc atttattatg gtgcagctat gctaagtctc gtgatgccat ttttgatcgt
     5041 ctctatacta gtaataatca aaaatggttt gggagacttc cgttatcctg taggaacgat
     5101 cattggtcag gagatacgaa tccttccgat gtatgagtat cttttccaga gctttctgtt
     5161 cctgttgttg tgggtgctct ttttaagtac aatcagtttt cttctatctg ctttatttga
     5221 acattctcta gtcaatcttt taggtacact tctttgtctt ttcttagcag agtatcgctt
     5281 gttttcttcg attggatgga tagaatcaat cagtcattac ttgccaactt cttatgttga
     5341 ttttcaaaat gtgatcatag gaggagatat tttctcgcca ctagcttcag aacaggttac
     5401 tttcatgaat ggtatcttga cacttggtat atggagtatc gttttattat tcataggtat
     5461 gggcactatc tatataaaaa agagctatta aaacacaaaa ataatagggg cggtgacaaa
     5521 aaccttgtca ccgtccccta tttcaaataa acggttttct agaataaata gttttcaaaa
     5581 gcttgcatcc gcagtaataa gaacctccca acaaaaatag ctcctcttat ttttatcttg
     5641 gttgaagtta ttacttgatg caaggcagct ttttttactg tgaacattgg ttatatatgt
     5701 ccatgttcaa aaatcatttg gacttcttca atggttttcg catcactgag cgccattact
     5761 tggtcgatgt ctgaacagaa aaaggctaaa tcttggagca ccgctaactg atgttctttt
     5821 tttaaagcca ctacaaataa gagtgtcgcg atttttggtt cctcttttgt tccaaagtcc
     5881 acaccatcag gcacttggac taaatagatt ccttcttcta ctacttcttc atctttgtca
     5941 gtcccatgtg gcaaggctac gaaattcccg atatagacac tcgctttttc ttgtctttcg
     6001 atcattgatt ggatatatgc cggtttgatt cccccttgtt gggtcatcca ctggccgatc
     6061 tcggtcaacg cttctttcca attttgatag gattgatcga gcaatatttt ttctgctggt
     6121 agctgtatca tcttttcacc ttcatttctt tatttcttca atcaggattt tcgctaacaa
     6181 ctgataaacg atttctttat ttcctgagcg gaagatctcg gtgttcaagt cattcatgat
     6241 gattgctcca ctgatctttc ctaaaagaat cccgtctttt tcttggattg gcgaaggcgc
     6301 cagcataact aacatacggg acaaatcgac tggctgtcta tccatccctt caatggtcaa
     6361 cggatgtttc aaattgaaaa tacaaaagat cggtttagaa atcaatgagc tggatgtatg
     6421 gaataacccc atatttgtat gaggaatacc gataggtgct tgttcatatc gcttaagcag
     6481 ccggcgatga accacctctt catccgttac tagtccttca ggaaaataag gaaataagct
     6541 gcgaatcgtt tcggaaatcg tctcaggatt atccagttct tggataaaaa aacgaccgag
     6601 taattgattg atttgatcca tgaaatgcat tgtttcctca taagtatctt ctatcatcca
     6661 ctcgttattg ctgttatacg taattttttg cctttttttc ttctcaatat gcgaaaaagc
     6721 ttcttttagc tgcttgactt catcttctag cagtagcggg gagactaaaa tatattttcc
     6781 accgtatcct ggtaaaatag atgtagaaat aacaacatca tattcttctt gtaaatcgat
     6841 tttttttaaa tcagcaatcc gatagaaatg aatttgttgg atgaagggaa aatacctttt
     6901 caatcgtagt tccaacatgc tagtagaagc taatccactt ggcgaaaatc ctgcaatact
     6961 gatattgctt tctttcggac ttcgttccaa tgaattcgca aaatgaagga ccatataagc
     7021 gatctcttct tcggataatt ttttttcttg aaaaatccgc tctactgctt tacggattgc
     7081 attcgcaact tcctcgtatt gaaccatgat tttttctaaa atcggattgg tcagtgtctc
     7141 ttcttgtaaa acggctcttg aaaacacacc agataaatga gtcaacagca ttttgtacaa
     7201 agtttcatct tcataaaaat ggacattcgt ctcttcactt acttcttgaa tcagttgttt
     7261 tactaaataa gcaagctgtg tatcgaacgt ctcttcaaag aaattctgat caaatgagtt
     7321 cgtgaagtca tttaataatc ctgcaaaaaa gacgatctca tttactggat aaagttgttt
     7381 tgtctcagaa gcgatccgtg aaaacaatcg tttagctgtc tgtagtaatt ctttgtttgc
     7441 cagactatta tatgtctcat ttgtcagtaa atgattttta gtcacacgct ccatcgtcaa
     7501 tgtcagcatc aaaaccaaat gttcaagctt tctatcactt agattggtct ttttttggat
     7561 caattcttcc ccgattactt tgcgtgcaag agatagatgt tgcggatcaa cgaatcgaaa
     7621 aaaataattc agtgatgcat cgaaagaaat actatgaaaa agttcatatt cattgatttc
     7681 taattctaat acattcgctg tcagaagccg gcggtatttt tccggtcctt cgatctcgta
     7741 tccctggttc cgaatgattt ccaaaggcag ttggcgaata ctttcttcca actgtttgat
     7801 atctgcataa aaagtggtat tactgatgcg atatgattcc atgaaatgag caagactcaa
     7861 cggctctgtc gtcagtaaca actcggctaa aatcgcgtgt tgtcgtttag cagtggataa
     7921 gtcattactt ttcccatctg tattttcttt taattgctct aatacttctt ctgatgcctc
     7981 aatgacaaat gagcctctag ctgctttttt caaagaagca tttaccgatt tcaatgagac
     8041 ttcaagatta tctaattcgc ggtaaatagt ccgtttactg accttcaata aattcatcat
     8101 tttttggata gatacaggtg acgggctact gagaaattct gctaataatt gtttttctct
     8161 gggcgataaa tacatcttat atttctccct tcacgagttt ttcgtattca ttcgtagcta
     8221 cccaatgttc aactagaact agccgaggga tcttttcttc tagctgttca gttacagcta
     8281 gttctctttg tgcgatataa atcgtttctt cttggatttt gattttttct attgattctt
     8341 ttgagataac aaactgtttt ttcgcttttt ttgctaattg acttaaaatc gtcatgccca
     8401 tagtttgtga gccgcgtctg ttgtttttat acaaaaatac aatattagca ggcgactttt
     8461 tttgttctgt gatatctgct atctcttttt tttcttcccg ctttggaaat tggatcgctt
     8521 cttttattcg tgacagcaag atatctgttt ccaaaaagtg atccagtaca tagatttgac
     8581 tttgaggtac tttttctctt gcaagacccg ctagttcatg ttgcacgata accagctgat
     8641 ttacttggtt attcaattca tagatagagc tgtatccgac agaaagatcg attttttctg
     8701 ctgctaattt ctttttcagc agggcggctc ccatagcact tgatcccata cctgagtcgc
     8761 aagcaaaaat gacggaatga atgatagatg gttccaagat ttctcccctt tctttgaccg
     8821 ttttgttctc tttttcttta tttggtaatt tcaatagtat cgctgcacaa atgaaggtca
     8881 caaatgtact gattgctatc cctatactta ccccagctag ttgtggataa ggcgcattgg
     8941 caaaaatcac gagtagtgac ccaggcgata caggtgcagc taatcccgta tctaaccatt
     9001 gaaatatcaa cgtgccgctt gccccaccag ccattacagc taaaaataga tacggtcgca
     9061 gcaagacaaa tggaaaatag atttcgtgaa tcccgccaat cgcatggatc atcaatgctc
     9121 cactcgcatt tactttttcc tgtttttctg caaaacaaag gatagaaagt aagatcccta
     9181 aaccaggtcc aggatttgcc tccatcaaaa ataaggaaga gtacccgact gtttgtgaga
     9241 attcgattcc taaaggtgtc aatacaccat gattgattgc attattgaaa aatagtactt
     9301 ttagaggttc taagatcaga ctgacaagtg gtaacagatt cattgtgact agccaagaca
     9361 caacggaggc gagcaacaag tgaacactat ttaaaactgg ttcaataaaa acgattccaa
     9421 ttatacaaat aacgctacca gtcagtccta ctagtaggtt gctgacaagc atttcatatc
     9481 cagccttgaa tttcacgtgg aatctagaaa caaattgttc atatacgatg ccggcaagcg
     9541 gcccgataat catcgctcct acgatttgtg gagcattgga acgagcgatc aaccctaaag
     9601 aagcaattgc accggcgact gccccttttt gtccccctac cgatttcccg cctgaataac
     9661 tgatcaagat gggtaaaagc agctggatca tccaatggca tacctcttct aatgtggtgt
     9721 gcaaatcgcc agacacacct tttgttgcta atgacaagat tccccaagcg ataaacagac
     9781 ttagatttgg catgatcatt tcatttaagt gatgtccagc ttttctcagt tgtttcatag
     9841 acacgcgact gctgttgttt gctttccatt tgtattccat ctttttcacc atacttctat
     9901 ttattgatgg acggatttta tgtagaaaaa gcagcaaacg aaaaaccgtc tgctgctttc
     9961 agctatctgg gaactatttg cctggttcag tcgcaatgat tgctagttca ccttggaccg
    10021 cccactcaga aacgccattt ggaataatac agcttgttcc tttttctaat ggatatgttt
    10081 ttccgtcaac gacaaggtct cctgctcctt cgattaccgt catcaatgta taaggggctt
    10141 gttttttgaa agatgtgatt cctttaatat cccactcata tacattgaaa aactcagttt
    10201 ctaaataagt gacgatcgat gaattccctt ttcggacttc tttgatttgt aattctggtg
    10261 ttttcgcagg gacagttgtt acatcgatcg attgttggat atgcagctct cttgtttgtc
    10321 cttgcgcatc ttttctgtcg tagtcataca cgcggtaagt cgtgtcagaa ctttgctgtg
    10381 tttctaaaat catgattcct ttaccaatag catggatcgt tccgcttggt acataaaaga
    10441 aatcaccttt tttaactggt actttcttca aaaggtcatc ccagcgccca tctttgatca
    10501 tctcagctag ttcttctctt gtctttgcat gatgaccata gatgatttct gcaccaggtt
    10561 cagcatcgat gatataccag cattcagttt ttcctaattc accttcatgt ttcatcccat
    10621 aggcatcatc tggatgtact tgtacagata gatcatcttc tgcgtctaag atcttgatca
    10681 ataatggaaa cactggttct gaaggatggc caaacaattc cttgtgttct gaccatagtt
    10741 catctaatct tttccctttg aattcgccat tttctactac actgacacca tgaggatgcg
    10801 cactgatcgc ccaatcttct ccgattttat cgttagggat atcaaaacca aagactgaac
    10861 gtaaacgact tcctccccaa attttttctt gaaaaactgg ttttaaaaac ataggttcct
    10921 gcataattca aactcctctc atttttcata gctattatag cattatttcg gtaataccgt
    10981 tttctctttc aaaaagtttt caacaatttc atctcgacat atgagatact ccgcacgatg
    11041 atcgacagga tgtacgcgat ttgacaaaaa tatcaacgct tcttgtgttt ttatatcaat
    11101 caagaaaaac gtacctgtat aaccagtatg aaaaagaatc gcatgaccgt cttctacatc
    11161 cttttttaag tcccatccta aagaacgata gccatttttt ttcggtgttt gatcttgcag
    11221 taaagaatca atcgtctctt cttctaaaaa acgaccatta cggatttttc ccttgttcaa
    11281 atacatttgg acaaaagtaa tgctgtcttt caaatcaata aagagacccg cgttacctgc
    11341 atgttcagcc aaaactcttg ctttcggatc atgagtttgt ccacgcaaaa cctcacccga
    11401 aggcagttgt tctgtgggaa cgattttttt ggaaggaaaa ggaagaaata agctgttcat
    11461 cattcctaat ggttccaata cttgttcttg aaagatttcc actgcagttt cttggtaaat
    11521 ttcctctagc atcaacccaa gaagaatcgt accggcatct gtatatttta cttcttttcc
    11581 tagttgctca cctggttcta gcttcaaata agcggcgatc aattcttcct gagatagctt
    11641 atctctgttt ggtatccatg ttttgatatc agaagtatgt gtcagtaaat gacgcaaagt
    11701 gattgtctga ttttcaaatt caggaagata tttatgaagc ggttgatcga gttctatctt
    11761 tccatcttct aatagacgta aaactaatga agtggttgca acgactttcg tcagtgaggc
    11821 tgcatcaaac aacagatctt ctgtcatcag ctgcttttca ggaacgactt gggcaaagcc
    11881 ggctgtaaat gtttctactt gattttcttt tatgaaggcg actgctacac ctggataaaa
    11941 tccttcttcc atctttttca aaataagctg tttcgtgtgt ggatacatct ttttctcctg
    12001 cttttctatc agattcttac agtccaagct taaagcttaa tctatgagga atcaaccttt
    12061 tttacacaaa aaaactgcgc gaaaaaccgc gcagtttccc ccggtatact attttctctt
    12121 tctatctcta gaataagcga tagtatgacc gttcataaaa tgacgagaca tgcgacaatc
    12181 gttaagaaag aaaaagttaa gcgtcgcatc gaatgtcagt tttattcttt tcttttggct
    12241 cactgacgaa ccaccattcg attcctatag catcatagat tgtgagtact gtgtgctttt
    12301 tgtctaagaa gaaatcaact gatagttgct gcaagtgagc aatcagtcct tccatgcttt
    12361 cagtatcgat catgaatttc agaaaatcaa gtccaatcac ttcatctgta ggcaaatcaa
    12421 ttgcgcctcc gctagcttct gtcaaaccaa catggaaatc tccttcattc aatacatgga
    12481 tgccctcttc ttcattatgt accttcaaac caagtacatg attaagaaat tggcgttctt
    12541 ttgttaagtt agtaacattt aaatggattt tttcaaaata agaacctgtt gatagtttac
    12601 tgaatttttc ttcagatttt cttaataatg cttcttgatc cattgtttct ggaatttctc
    12661 tttggtcgtt cttattctct tcatggtaaa tttccaattc attctcttct gggtctacga
    12721 gcaaaatccc catacgtcca tgatcttcta aagcttcttt gattggataa ttcattttac
    12781 ggatacgaca aaggatatct gccatttctt ctgtgctagg gataatcaat gaaaaacggt
    12841 tcagcttttt gatcaccccc atgtgatcat tcgctctagg actttcttcc agcagcaaca
    12901 tttcacttcc agcttcttct gttcctaaaa tggctaattc gttttcttct cttttcaaat
    12961 caaagccaac aacgttcttg taaaaatcaa tcattttatc tcggtctttc acccgaatgg
    13021 ctacactttt taaataggtg gcagccccca attgaaaatc tttcatattt cttgctcccc
    13081 tctacgtcaa gctttatttt aacgatggat tcttcttctt tcaagcaata actttgattt
    13141 tgttaaaaaa aatgtgagaa aattcgcatt ttgcttgttt tttgtaaatt aatgagtaaa
    13201 aactcttata aaaagaggtt gtgaaaaagc tgttctgcat caagtaataa gaacagccaa
    13261 acaaaaatag ctcctcctat ttttcgtttg gttgggctta ttaccgcaga tgcaagcttt
    13321 tgaacaccgt ttaaggaaga ggttgtaaaa tcagcggttt gacctgagta ttagagatac
    13381 aaaacggaaa aatagcttct catattttgc cgttttttga gctaataccg aaggacagct
    13441 gattgaacac cgtttattcg gaaaaaggga ctgtgacacg acttttgtca cagcccctaa
    13501 aaaaaataat aaatttgtac tattctatga agcttcttct tcagaaaact gactgttata
    13561 aagatctgca tagaatccgt ctttttccat caatgtatcg tggtttcctg tttctacgat
    13621 cgaaccatga ttcatcacaa taatgttgtc tgcatcgcgt attgtagaca agcggtgagc
    13681 aacaacgaaa cttgtccggt tttccaatag gcggttcatc gctttttgaa tcagtatttc
    13741 tgttcgtgta tctacactag atgttgcttc atcaaggatc aggacatctg gatttgctaa
    13801 gaatgcccgc gcaattgtga ttagctgacg ctgcccttgc gaaatattgc ttgcatcctc
    13861 gtttaataca gtgttatatc cttctggcaa tttacgaaca aaatcgtcta cgtgagcagc
    13921 tttagcagcc tcaatgattt gttcgtctgt tgcatcgtcg ttcccatatt tgatattgtc
    13981 atagatactt cctgtaaaca gccaagtatc ttgcagtacc attgaaaact gtgcgcgcaa
    14041 ttcatcacgt gaaagatcac gggtatctac accatcgtaa cgaatactac ctccagaaac
    14101 atcgtagaac cgttcaagaa ggttgatcag tgtcgtcttc cctgcaccag tcggacctac
    14161 aatagcgacc atctcaccag gtttgacatc caagttaaaa tcagtcatta gcaagttatc
    14221 tggtgtgtag ccgaattgaa cattttcaaa acgaactttg tatggtgtat ctttttcttc
    14281 tggaaggcca gatttttcat tggacatctc ttcttcatcc aacacttcaa atacccgttc
    14341 ggctgaagca actgttgatt ggatagtgtt catcaaactt gcaagttgag tgattggttg
    14401 agagaactgt gttgtatatt gcaagaacgc ttgaacatcc cctaatgtca tgttcccatt
    14461 tgcaactttt actccgccta gtacagcgac gaacacatag cctagatttt taacgaaatt
    14521 catcaacggc atgatgattg ccgaaataaa ttgagctttc caaccagcgg catacagatt
    14581 ctgattttct ttttcaaata cttcctggtc tttttcagta tgattgaatg ttttaacaat
    14641 ggtatgacca ccatatgttt cttctacttg gttattcaat aaacctaaac ttttttgctg
    14701 atctgcgaaa aacacttgtg atttcggcgc tacgatcatc acgatgatca agcttaaagg
    14761 gatcatcaat aacgcgacta acgtcaattg ccagctgatt gaaagcatca tcacgatgac
    14821 cccaatcaat gtgactgcac tagttacaaa ttgagtcaaa ttttgctgca gcgtgcttgc
    14881 gatgttatcc atatcattga ttgctcgaga catgatatcc ccatttgtat gtgtatcata
    14941 ataggaaatc ggtacacgat tcattttggc ttccaaatca tgacgtaatt cataaactgt
    15001 tcgttgggaa acacgtgtca taataaattg ctgtaaaaag ttgaatacag cagaaatcaa
    15061 atacatcacg attactgtcg caatgatctg cgcgatttta tcaaagtcta tcggaaattt
    15121 tgttacttgt tggccttgtt gcatctgttg agcgccagcc attacacctt tgaatatttc
    15181 tgtggttgct ttccccaaga cctttggtgt ttggatttgg aagatcacgg ctgctattgc
    15241 tagtacaaat acagcgatga tcgcaaccat acgtttagac atatagccaa acaatcggcg
    15301 taccgttccc cagaaatttt taggcttttc accttttaca ccgagatttc tgccaggtcc
    15361 accatgtcct ggaccgcctg ctggtccatg agagggacgt gtgtttgttt tactcatgct
    15421 aagtcctcct ctcttagttg tgaatgaacg atttcttgat aagtttcgtt tgttgctaat
    15481 agttcttcat gtgttccttt gccaaccagt tttccttcat ctagcacaag gatcatatct
    15541 gcatccatta ctgtacttac tcgttgagca actaaaacgg tgatactttc tttcatattc
    15601 gttttcaatg cttggcgaag attggcatcc gttttgaaat ccaacgctga gaaggaatca
    15661 tcaaacacat agatatctgc tgttttgact aatgcccgtg caattgccag acgctgtctt
    15721 tgtccaccag agaagtttcc tcctccttgt tccacatggc tatctaagcc atcttccatc
    15781 tctgaaacaa aatctttagc ttgtgcgatt tctaatgctt tccaaatcat ttcatctgtt
    15841 gcatccggct taccatactg catattgtct cggatcgttc cagagaacag aactgctttt
    15901 tgaggaacaa agcccattaa ttctcgcaaa ttatattgag tcatgtcact aatgtccgtt
    15961 ccatttattt ggatcgaacc agattcgatg tcatataatc gagggatcaa attgactaag
    16021 gtcgttttac ctgaaccagt cccccctatg attgcgacga tctcgcccga cttggcttgg
    16081 aaatcaatat cttccaatgc aagtttttct gctccatgat atcgataatt gacatgattg
    16141 aaggccaatg ttgcgttttt tccagcaaaa gaaactgttt taggattttc agggtcatgg
    16201 ataccgattt tttcatccaa cacttcatta atacggtcag ctgaagcttg tgcacgaggc
    16261 accatgataa aaatagcgga aagcatcata aagctgatca agatctgcat cgcataagtc
    16321 ataaatgcaa tcagattacc gacttccaaa gtcatatctg ctatgtagtg tccaccaaac
    16381 caagtgattg ctacgtttgt accgctcatg atcaatgtca tcattggcat catcaatgcg
    16441 acgatcgtat taactttgat tgccgtattt gtataatctt tattcgctaa atcaaaacga
    16501 ttttcttcaa agcgtgtctt atcgaatgct cgaatcactc tgacccctgt caatccttct
    16561 cgaaatacca ggtttaaacg gtcagttttc ttttgcatac ttttgaataa tggaacagca
    16621 aagtacatga ttccgccgat caaaataatc attactggga tgacaactaa gaagattttt
    16681 gtcaactgat gatctttttg ataagcaagt atgctcgcgc caatcaacgt gattggtgca
    16741 ttgatcatca tacgtaaaaa catttgtgta accatttgga tttgagtcac atcattggtc
    16801 gttcttgtga tcaaagaggc cgttccatat ttatcaaacg catcttttgt cagactctct
    16861 gattttttat agacatccgt acgcaattgc ttacccagtt tctgtgattc acgagtagca
    16921 aaaaatgtat ttgcgatagc agctaagata ctgatcaaag aaaagccgat catcacaaaa
    16981 cctgtatgcc aaatataatc gacatctcct tgcgctaccc ctttatcaat aatattggag
    17041 gtaagtgtcg gcaaatataa atctgccagt acttggatca ccatgaaaac tgcagctgca
    17101 attgctgaag tcaaggagat ccgttttacg atttttagca tctagttccc ttctttctat
    17161 ttatatactc cgtttttcag ccaagaaagt ttcaaattga attcactgat tgcttgctct
    17221 actgagtaat cttcagatgt tgaaaataag cgatacgaat gcgcaattgt tgtaaataca
    17281 gtattcatca ctaattggat cagtaattcc aattcatgat cattttttac tttcagcttc
    17341 gtccgatcga tcaattcaag caactctttt gcatcttgtt tgtgttcttt atgtggatcg
    17401 tgaggcgttt tttggcgact cgtatgagga gcgacttttc ttgaggcacg gtaatccatg
    17461 ttcataaaca agttacgata aaaagaagca ttctcgcctt ccaaaatctc ataaatcatt
    17521 ttagaaaaat aggattcgaa tcctttgaat agatcaccat cggattcttt cattagttgt
    17581 aacatatctt tagagctgtc acgtctcatt gtctcaaagt aataaaaata aagatcctct
    17641 ttatcttcaa aatactgata gaaactgcct ctagggatat ccgctaattt gacgatatta
    17701 gcaatcgaag cttcttttaa gggtactcta gaaaactcga ttctcgcagc ctcgattagt
    17761 cttttttgtt tttctttagg caaatggaaa aatgtctgtg tcggcatatg gatcctcctt
    17821 tctttcaaga tgacacattg tcatatgacg ctgtgtcatt ataacacctc ctacctgttt
    17881 tgcaagacat ttgcatagtt tttttcatta tcatccgata cattaaaaaa gtgataagag
    17941 gaatccttcc atttgaatta atgagagttg cccattaaaa tagccacata ctaaacaaag
    18001 gatgagataa atggcccaat caattagtgt ccaagacttc aataaattgc ctctcgatgc
    18061 tgacagcatc gttttagata caagaaatac cttagattac acaaaaaacc acttaagcca
    18121 ctcgctttct atccccgctg ctatcttgcc aagacaatta aaaaatctag atccaaagaa
    18181 actttattat attctaagct atacaggcag gcgatcagaa gcattagccg atcaacttac
    18241 tgctaatggt tttcgtgctg tttatatcat tggtgggatg gaagctcttc agtcgagtgt
    18301 tgcttgaata ttgcttgtta gattcaaaag aggctgtgac aaaaaatcgt gtcacagcct
    18361 cttttatacc ctgtcttttt ttagttattt attcttcaac cttatcaata tgacttgata
    18421 gccttttctt tttctcatag ttataacaat catagcaata aaaggagaag gtaagcatat
    18481 ggcatctgtt ttagtagtca aaggtcatcc cctaactgca gaagaatcgc gcacagttaa
    18541 ggcattgacg tcttttttaa caagttataa agaaaatcat ccagatgatg aagtgactgt
    18601 tttggaactt tatcgcgatg atattccgga aatcgatgaa gaattattat caggttggga
    18661 agcattacgt gctggtgcag aattcacttc cttatcagaa agtcaacaac aaaaaattgc
    18721 tcgtttcaat gaattgactg atcagttcct tgctgctgat aaaatcgtta tcgcaaacgc
    18781 cttatggaat ctaaatatcc caacaaaatt aaaagcttgg ttcgataccg tcaatgtagc
    18841 tggaaaaacg ttccgctata cagaaaacgg gccagaagga ttagtgacag gtaaaaaagc
    18901 actgcacatc caatctaatg gcggtgtata caacggacaa gactttgcct ctcaatatgt
    18961 aaaaggtatt ttaaactttg taggcatcga tcaagtagat cagctattca tcgaaggaat
    19021 cgattatgac cctgaccgtg cagatgagtt gatgcaaaat gcattagata aagctgctgc
    19081 tttaggtaaa tcattttaaa aattgagata aatgcataca aaagagacag aggaaaaaat
    19141 cttcaaagca gcatttgtac cttggatatt ttcccatctg tctctttttg ttattctttc
    19201 tgctttttca acggattttc ttcataaaga gaagagattg ttgtgtacca ttcaaaaaca
    19261 tgagtaatca ctactttagc tgctgcataa acaggaatcc ccaagatcac accgatgatt
    19321 ccgaacaatt tcccagaagt cagcagaact aataaaatcg ttactggatg gattgctaac
    19381 tgattcccta gtactaatgg agagatcaag cgtccttcta ttgtctgctc tactgcaaaa
    19441 acgatcagta ctttgatgat catgaatgga cctgctacaa tggctaaaaa gatagccgga
    19501 atcatcgcta aaaatgatcc taagtaaggg atcaggttca aaaaacccgc aataatcccc
    19561 aacgtgacag catactctaa accaatgacc gcaaaaccaa tcataaacat gattgccaca
    19621 gcaaaagcca cagttagttg tcctcttata taagaagaaa cttgactatt catttcactc
    19681 agcacattca acgtcggttt ttgcatgcgt gtcggtaaaa atttgacaaa ataaggtgct
    19741 aattgtttac cgtctttcaa tagataaaat aagataaacg gcatcgtcag cagagccact
    19801 aaaatagtcg ctaccgcgcc gacaaaactt ccaagactct gaactgtact cttagatata
    19861 tcttggatca tatcgcctgc cgaattcatg aacttatcac ctgctgtttc caactgttcg
    19921 cgaaattggt tgaacagcgg gtcccgcaaa atctcggtta atttattatc aatcgtatct
    19981 acatattgag ggaagttact gatgaagctc actgtttgtt cctgaatctt agggatgatc
    20041 actacgctcc cccatgcgat tagtgcaaca accaaaacaa acagcccaat gatactgtaa
    20101 agccttggta cttttcgctt ttcaaagtaa tcaactaccg gattcatcaa gtaatacaag
    20161 attcctgcta aaatgatagg cagacctacg attgctaaaa attgccagat tggtgcaaac
    20221 aaatatgaaa cttttgtaaa taaaaagacg atcagcaata ttaacaatac aacaagtaag
    20281 gctgtgacta cttgattatt taaaaaccag cgccaaaacc acgataccgg tctgttcttc
    20341 ttattttttc cttccataat tcctcctgtt agttataaaa aatttggctt cccaaaccaa
    20401 tagcaggcag tctatgcgga tgaagataga ttccatttgc aatttgtcct tcttctggac
    20461 aagcatcaaa aatcaatgat acgtgagcta ctgtctctaa attcccattg gccatcggac
    20521 cgacataatc gatcgtatat acctgatcat caaaagcaat tgttccgcct gctttcaaag
    20581 aaaaaggttc gtcttttgat acttcttgaa tcaccgaata ttttcgtaag gcagctgttg
    20641 ctgttttatc gaacaaaatc agcatgggtt cttccttgtt tattgcttct gtcccaattt
    20701 ctgtaatctt tgcctgaatc attgcactct ctcctttaat tgctttcaaa aacagtataa
    20761 cacattctca ttctttagcc gtgtggaata attatgtgat agaataaaaa cgaaaactat
    20821 ttcattacaa ttaggaggaa tcagctcata tgatcgaaaa gataatttta ggaacctata
    20881 cgcgtcgcga aagtaaagga atctatacga tcgaccttga tacagaaaaa gaagaattag
    20941 ccaacctttc attagctgtt gaagaaaata gccctaccta tgtagcaaaa agtaaagctg
    21001 gcaatcttta cacagttact agtgtggatg gattaggtgg tgccggtgcg tacgataagg
    21061 attttcattt tttgaatgcg gtaacagagt ctggcgctcc tttgtgttat gtagcggttg
    21121 atgaagcacg tcaattacta tacggggcga actatcataa aggtgaagta aatgtctacc
    21181 atatattagg agatggcgaa ctgaaagcag cagattcaat attccatcaa gaagcgacag
    21241 gtcctcataa aaaccaagat catgcgcatg tccactatac ggatctgact cctgaccaac
    21301 gattagtcgt atgtgatctt ggtacagatc gtgtgtatac ttatgatgtg tccgaaaacg
    21361 gcaaattgaa tcttgtaact accttcactg cagagccagg aacaggccct cgccatcttg
    21421 tctttcatcc aaatggacaa ttcgcttatt tatttggtga attagacagc acagtccgcg
    21481 tgctttctta taataaagaa acaggtgctt ttgaagaatt acagaaaata tcgaccttgc
    21541 cagaagaatt cgacggtgaa aatggagggg cagctatccg catttcaaat gatggcaagt
    21601 tcctttatgc ttctaaccga ggacataact cgattgctgt attcgcagtt tttgaagatg
    21661 gttcccacat tcaaaacaag caaatcatct caacagaagg ggattttccc cgcgatttcg
    21721 cactagatcc aagcaataat tttgtcgtgt gtgccaatca gaacaccgat aatctgacat
    21781 tatatcgccg tcatcctgaa acaggattac tggaattact gaaaaaagat gtctatgtac
    21841 cagaatgtgt ctgtgtttat tttgatcgtt agtaagaaaa ggagaatgaa atgaatcagc
    21901 aagacgtatt agacagacta cgggaagaac taaatattcc tttctttgat gggaaaatcg
    21961 aagataaaga gtatagcgaa gaggaatatc agaaactcaa agccgattta cagaactact
    22021 ttgaacaata tgtacagaat gtagaaaact aatcagcttt ccatactatc tgaaaagaac
    22081 atcaggacaa gacttttccg tctatcctga tgttcttttc tacaaataaa aaaccgccga
    22141 gatggttaga ctcgacggaa aaggagtatt tactcgattt tgagtaagta caaggttgtt
    22201 gttggttata ggtatgtcat tatcataaag gattttgatc actctatcat aaaggtaata
    22261 ttacatttat attagataac tctagttttt attgttatca aagatttctt ttattttttc
    22321 aacaacaaat tagtcatttt ttggatggca gctgtcaatt ggtctgtcgc ttggtcttgt
    22381 tttgcttcag atgtattgaa tagatcttca tctacccctg attcaagatc gatactttgg
    22441 atcatttctt cacagcctgc tacatatgaa agataagctt tttcaaaatt tttatgaatg
    22501 cccattgctt ttgctggtgg acgcaaagta ctgactttct taagcattgc ccgatatttt
    22561 tttgttcctt cttcaaataa caggatgatc tcttcaagag tcgatttgtc cagttcactt
    22621 gtttttcctt catcaattgc gtttctgatc acttcatatt tcggatgcat tccttctccg
    22681 attgcttctg tttccttgac gatttgatcg atggactgca cataatagcc aatattcggt
    22741 aacatgttcg ttttcctact ttctccattg ttgttattat ttattctact tgtttttatc
    22801 ctcaaatgac aagtacttga aaaaatttaa tggtttctat acagctcgcc attcttattc
    22861 gtgctcaaag aaaccatctg ctaaactata ttgtttccct gcgacaatgt catattggat
    22921 caattgatat tcgtcgtaaa tctcttgttg cgagcgattg aattgcgctt ctttatacca
    22981 ctgtccgttt tgatagtaca gttctcgttc aaacgccgga agttcctgtt ctaatgataa
    23041 aagcagctga taaaagccat ttgttgtctg attcgtctgt tccattagat tcgctgcaaa
    23101 ataaaacgga ctggtgattg catcgtgagt cgtttgcttt tctaattctc ctttactgtc
    23161 gaacataaga aattgtgttt catgcaatgt ttgtttgtca ttttttgctt ggatcgtatc
    23221 tgaatagatc cctggaagat gatcccccca aaaaacaact aaagtccttc tagaaagatt
    23281 cttcaattct tccgtgaact gcttcagtgc cgtgctgcta taggaaatat cttgcagata
    23341 attctctaag tcaagtgtcc cacttccatc tgaagttttt gcaggatagt ctagattatc
    23401 atactttcca tcgtagggca tatgtgtctg catcgtgact aaatgaatga actgaggtgt
    23461 tttttcttcc ttgagaagtg tcattacttc tttgtaagct gactcatcag aaatatatgg
    23521 attattctct atcgtatccg tataggtcat cgtacgctcg ctgatgaact ggtcaaatcc
    23581 taatgtctga taaacatcct ctcttttata catcgaagta ttgtatggat ggatcgctgt
    23641 cgtctggtat gattgtgcgt ttaacgctga aacgatagaa ggaagctgat ccatttttgg
    23701 tacaagcatc gtgtaagggg tggtgagttg cgcattaaat aacgccatag aaaaaccagt
    23761 caatgcttca aattcgatat ttgctgttcc accgccatag ttttgagaaa gcatattgcc
    23821 actatatgtt tgatcagcta cttcataata atctgccaat ggctcaccag atacttctac
    23881 gccgtttaat cgactaggat ctgagaaact ttcactcatc acgaacacga tgttcggcga
    23941 ctcttcctct acagttttat ttttttcatc ggctagcttc tggtattttt cagtgatttc
    24001 tttgatcttt tctttcgaat atccttcagg ttcatccatt ggttctacct tcagattgta
    24061 caaaaaccca ccgataaaac cagtgttata gtagttcatt ttctggctgt aaggtatcca
    24121 tagtgccgtt ttattatatg cttttcgcaa caaattatcg ggattgttga aattactgat
    24181 ataccctagc agtccaattg ccacaagcag tgtcgttaat cggatcaatt ggaatcgcct
    24241 tccttttttc aggcttcgaa acatgtacca gcaaaacaat cctatcacgg ttcctgcggc
    24301 agctaagatc actgtaaaca gcatagtgcc ggtcatatct ttcagcaatc cgatttcagt
    24361 gatcatcttc aaatcgtctg gataaatcgg ttcttgccga taactcattt tcatataatt
    24421 tgcaaaacct aatacaccga tggctacgac atacgtaagg gaacctaaag ggacagatcc
    24481 tgctagtgca atcagaaaaa taagaataat cagcaagacg agacaggcta agaagaattt
    24541 ttccgtatgc caagaaaaag caaatttcaa cgcaaggtct acggatagat cattttgaca
    24601 ccactgcaaa aataaattac taaaaacaac aagaaaaaag atactgatga ttgctgctgt
    24661 tccttttaaa atctttttct gtttggtcga aagtctgctt atatatcttt tcaaatgctt
    24721 gctccttcat ttctatcaat aaaagaatgt tgcttctctt attttagttg tacgaaattc
    24781 gaaagtaaag aacggaaaga agaattaatg aaatccaaat attctctttc tttatggcct
    24841 ttctggtttc tttaataagc ggacctttcg tactccagaa attttttcta gctgttgttt
    24901 cacttgattg agctgttcaa aatcagtact gtctatgtca atcaatatgt agacatgctc
    24961 attcttatgg ttacgcgata tatctgcgat cgctagctcg ttctcattca gcagagaaaa
    25021 tatctctgct aatatattgg ttttcttttg ataaaatata gtgaatcgaa acggcgcttg
    25081 gaaaaacatt cgtgcggatg gataattgac cgcttctcta accgtaccga acaaaagata
    25141 atcttttaag gcttcaactg ccaaacgtcc gctgtctgcc aaagcttcct gagtcgatcc
    25201 ccctagatga ggcaacataa gtatacggtc attttctaag aactcttctt ctggaaaatc
    25261 agtcaagtat ttagccagat gttgtttttc caatgcttgc ataacagcat atttatcaac
    25321 aatttcactt cttcctacat tgataagtac agcatctttt ttcatttttt ctatattcgc
    25381 ctgatcgatc aatccttttg tatcttctgt caacggcagc atgactacga tgtaatccga
    25441 ggtagaaaga actgtttcta aatctgcttg ccgaacataa tccaactggg catcgcggat
    25501 agaataaccc aagacatcca tccctaagct atagcaactt agcgctactt ttgtgcctat
    25561 cgctccaaga ccaagaagac cgatggtttt gccttgcaat tctcgtccca cataagcact
    25621 tcttttgttt tctgcctgtt ctaaaatatt aggacctgtt agtgtttgta ccatacgact
    25681 tgcttcgatt atcggacggg aagataagag caaacagcac aaaacaagct cttttactgc
    25741 attagcattt acacctggtg tattcatgac gatcgtcccg ttttcagaag ctttttcaac
    25801 gttgatcgtg ttcaccccaa caccagctct tgaaattgct agcaaatctg gtgtaagcca
    25861 ttcatctttc actttcgtac tacgaataac tattccttcg gctggcaaat catctattat
    25921 tttgaaatat tccccttgta acttttctat ctcttgttct ggaatagcat caatcaaatg
    25981 aacgtgatac ataaaacccc ctccttacta acaagtatct cgaaatttct gcaattagac
    26041 aactgtttac catttgactt cctagaagca aaaagagcag ttagagcaga gtaggctgag
    26101 tgataaaaat aaggctatga caagttactg ccataagcct tattttcgag agcaaaatat
    26161 tgagggtgag atatcttgat aaatggtgtt ccgttagctg acattgataa taagactaaa
    26221 tttcaaaaaa gttgaaaagc aaatttcgtc aatctcttct tatttcttaa aactaagtgg
    26281 ctttttcaca acctcttttt atctaataac cactgtttcc aactcaacta attttgccca
    26341 cgtttcaatt tgatctgttg ttagatttag cgagacaacg gtatgatgac cgccacctgc
    26401 ctgaatccat gaatggacac cttcatggaa attcggttta gttttccata acacacgtgc
    26461 aacaggtaaa ttaggtgctt cagtcgttgg ttcaaaggct tctacttcat tgatcagcag
    26521 tttataatgc gtaccgaaat ctgccatcga tacgactacc ccttctcctg ctttcccatc
    26581 aaatacaaga cgcgccggat cttctctatc tcccattgat aaaggagaaa caacgattct
    26641 tggtttcgtc gcagcaagcg tcggatctac ttccatcata tgggattcca agattgcttc
    26701 ttggccacta gctagctcgt aagtataatc ttccatgaat cctgtatctt tccctcgagc
    26761 catgattttc agcaaccgat caatcgctgc agttttccag tcgccttccc cagcaaaacc
    26821 gtatccttct gccatcaaac gttgtacagc tagtccaggt agttgtttca ttccatacag
    26881 gtcttcaaaa ttagtcgtaa aagcgttata gcctccttct tctaagaaac ggcgaatacc
    26941 gatttcctgc tgagcttgta cttttacatg ttcctcccat gtcttttctt cataatcacc
    27001 atagtcgaag gtatacaatt ccttgtactc ttcaaataat tgatcgactt cttcgtctga
    27061 tacgcgatcg attacttgta caagatctcc gataccaaaa taatcaacag tccaaccaaa
    27121 ttgaatctgt gcttccactt tgtctccttc tgtgacaccc acgtttctca tgttgtcacc
    27181 aaaacgagcc acttttattc caaaactttc attataggct actgcaacat ccatccaatc
    27241 agcaatctct ttttggatct caggtcgttt ccagtagcca acgacgattt tattttgttt
    27301 atttaatcga gcattgatga acccatattc gcggtcacca tgagcggatt gatttaaatt
    27361 catgaaatcc atatcgatcg ttttccaagg aatgctttcg ttatattgcg tagctaaatg
    27421 aagcaatggt ttttgtagaa gctttgtccc gcggatccac atttttgctg gtgagaaagt
    27481 atgcatccaa gtgatcacac ctgctacttc ttctcgataa ttgacctctt tcatgatttt
    27541 tgtgatcgta tcagcagtaa ctgctaattc ttgaaggcgg attggataag gcaattggcc
    27601 attttcattc agttcatcga ccatttcttg tgcatgtttc tttacttctc gcagtgcttc
    27661 ttccccatat aaatgctgtg atcctacaac aaaccaaaat tctttttctc caatattcaa
    27721 cataattagc cactcctttt atttgttttg tccgtaatac gcattttttc cgtgttttcg
    27781 taaataatgt ttatctaaaa tccgttgagg cagctcttct gaaaatgaat tgagctgtct
    27841 ggtaaataaa ttcatcttgc atacttcatc tagtacgact gcgttcatta ccgcactttg
    27901 cgcatctttc ccccaagtaa atggaccgtg tccgtgtaaa agtacccctg gaattgctaa
    27961 gggatcaatt ttgcgttctt tgaatgtttc tatgataact tttcctgttt catattcgta
    28021 cccgctgtcg atttcctgtt gtgtcaaaaa tcgagcacaa ggtaccgatc cataaaaagt
    28081 atctgcatgc gtcgtcccca tcgcaggaac atccaatcct gcttgtgccc agatcgtcgc
    28141 ccatgtcgag tgagtatgga cgattcctcc gatttgagga aatgaacgat ataaaacagc
    28201 atgagtaggc gtatccgaag agggattgag tttaccttca atgatatgat tgtccaagtc
    28261 cacaacgacc atgtcgtctg ctgtcatctc ttcataactg actccgctag gtttgataac
    28321 gaaatatcgt gtttcaggat caaaagcgct cacatttccc catgtatatt tgacgagtcc
    28381 gtgtttaggc aagtcaagat ttgcttggta tacttcttct ttcagttgtt ccagcatttt
    28441 ctatcactcc tttttcttgc aattgatgaa tcgctgtttt ttcaatgtcg atcccctcac
    28501 ggtaacgtct cataaatatc tgatagcctg ctatttcttc tgctgaaggt gtgatggtga
    28561 ttccttggtc ttgtccaaac acgtcttctg ccaagaagtt ttctaaagac ttcccatgtc
    28621 gatccatcat ataggccgct aataacgcga ttccccacgc tccaccttct ccggctgtgt
    28681 ccatcactgt aactggtgcc tccatagcag atgctagaat ccgctgtcca acttctggtg
    28741 ttttaaaaat ccccccatgc cccactaaac gatcaatttg gacattctca gatttcaata
    28801 tatccattcc gattctcatt gcaccaaaag cactggctaa atggatccgc atgaaattcg
    28861 ctaaatcaaa acggctacct ggtgtacgta caaataatgg ccttccttca tttactcctg
    28921 taatgttttc accggaaaaa taaccataag aaagtaatcc cccgcaatcc gtatcgcctt
    28981 ctagcgcttt gttgaataat accgtgaata atttatctct gcttatctcc atacccaaag
    29041 aattggtaaa ttcttcaaaa atactgaccc aagcattgat atccgaagag cagttattcg
    29101 tatgaaccat gcctactagt tctcctgaag gtgtagtgac catgtcgatt tccggatgga
    29161 cattttctag ttctttttct aatacgatca tagcgaaggc ggaagtacca gccgaaatgt
    29221 tccctgtccg tttggctaca ctgttcgtag cgaccatacc ggttcctgca tccccttctg
    29281 gcggacaaac cgggattcct ggtctcaaat ttcccgtagg gtcgatcaga taagcccctg
    29341 attcgcttaa cttgccagct tcttctcctg ctactagaac tttaggcaaa atgtgatcca
    29401 agtcaatcgc tacgtgcgct ttttcgatta actgaccaaa aatatttttc atttcttgat
    29461 ggtaggtttt cgttgaagga tcgataggaa acatgcctga tgcatctcct acgcctagta
    29521 ctttctcacc agtaagctgc caatggacat aacctgcaag cgttgtcaaa aaattaattt
    29581 ctttcacatg ttcttcttta ttcaaaatag attgatacaa atgagcgata ctccatctct
    29641 gcggaatatt gtattgaaat ttttccgtta atattcgttc tgcttcttca gtgattgtat
    29701 ttcgccaagt acgaaatggt actagtaact gttccttgct atcaaatgct agataaccgt
    29761 gcatcattgc actgaaccca atcgacccga ttgtcgtaag attctcgcca tagatttcga
    29821 atacttctgc tgccattttt cggtaactga cgcgcagtcc tttccaaata tcttctaatg
    29881 aataggtcca gataccattt tctagtttgt tttcccactc ataactacca gcggcaatag
    29941 gagtaaaaga tgaatcaatc aatacagctt tgatcctagt tgatccaaac tcaatcccta
    30001 aagatgtacg accatctatg acatctaaca tactttgcgc atttacttcc ttcataatga
    30061 tttaactccc tccttctcgt caaacctgat caaaccgtct ttttagtagc gcttacaatg
    30121 attattgtat acttttgtac gtacatgtca agcggttatt tacaagaata caataaaaaa
    30181 cacttgtttt gtacgtacat aagttataaa atgaaattgc ttacaaaatc tgatcaaccg
    30241 ccttctcgaa attctagaag gagagaatac ttatgaaaaa agaaaaaaaa gtttcctcat
    30301 cgtttattta tttttttggc gcatttggcg gcattctatt tggatatgat attggtgtta
    30361 tgaccggcgc cttacctttt ttacagcatg attggggttt ggcaggtaaa gcttctttga
    30421 taggatggat cacgtcttcg gtcatgttag gtgcgatcct tggcggctct ttatctggtc
    30481 ttctttctga taagcttgga cgacgaaaaa tgattcttct ttctgcactt atttttatgg
    30541 ctggttctgt cctttctgca tctgcccctc acaatggttc ttattttctg attgcagcaa
    30601 ggattcttct aggtttagct gttggcgctg catctgccct agttcctgct tatatgtctg
    30661 aaatggctcc tgctagacta aggggaagat tgtcagggat caatcaagtg atgattgctt
    30721 ctggcatgct cctttcctat gttgcagatt atttgctaaa agtgttgcct gaaacgatgg
    30781 cttggcgcgt gatgttaggg ctcgctgctg tccccgcgct gattttattt ttcggtgttt
    30841 tagctctacc agagtcaccg cgttttctta tgcaatctgg ccgcttggaa gaggcaaaaa
    30901 gagtattgaa ctatattcgg acaccaaaag aagctgaaca ggaattcgaa caaatccagc
    30961 tgaatgtcaa acaagaaaag acaaccggaa cttcttggca tactttgttt ttagaaaaat
    31021 atcgttcctt agtcattgcc ggtattggtg tagcagtatt ccagcaattt caaggagcta
    31081 atgctatttt ttactatatt ccgctgatcg tagaaaaagc gactgggcat gcagcgagcg
    31141 atgcattgat gtggccgatc atccaaggaa tcattttagt tgctggttct ttgctctttt
    31201 tggttattgc agacaagttc aatcggcgaa ctttattgaa aataggcggt agcgtgatgg
    31261 gactttcatt catcctacca gctgttttag gaactgtact ggatgctcat acaaattcgt
    31321 tgttgattct cttgttttta tgtatttatg tcgcatttta ttcttgcaca tgggctccac
    31381 tgacatgggt aatcataggc gaaatattcc cactagctgt ccgcgggcga gcatctggcc
    31441 tagcctcttc ttttaattgg attggttctt tcctagttgg cttgcttttt cctgtgatga
    31501 ctgcttctat gtctcaagaa atcgttttcg gcatttttgg gatcatctgc tttttagggg
    31561 ttttatttat tcaagagatc gtaccagaaa ctcgtgggaa atctttagag gaaatcgaac
    31621 aaagtgcatc taaaaaaact tatcctaaac gtatttctat ccatcattct taaagaggtt
    31681 gtgacagaag tggtcagctt caagaaataa gaaggaaccg cttagtttcc agtcacaagg
    31741 aacaatttca aaaaacagct tctcatgttt gatgaatatt gtgacttgtg accagttggt
    31801 aggagaacac cgtttagtgg agaggtggtg aaagaaacgt tcagccttga gcgatgacaa
    31861 aagctctcac aaacattgcg acgagtaacc gtaggagcaa taagaggcgg taaaaacccg
    31921 tctcttattt ttcgttttct ttcactgttt cccgttcaac tagtacaggt tcatagagaa
    31981 tatttggctg tgcctgtcct ttttcaatcg ttgtgacgat ccaccgtgcg gcatcttgtc
    32041 ccaacttttc ttttggatgc gtcaatgttg tcaatttttt attccctaaa tggcttaaag
    32101 aagaatcgtc tgttcctacg atcgataggt catctggaat atgatagcca ttttctgtca
    32161 acttatctag cattaaacta gctatttgat cgttatagca aatgatgcca tctaaagctt
    32221 gttcttcttt caaccgttgt actgtttttt cagcgattgt ttctcgtgtt tccgtggtga
    32281 aagtaatgat atcttccgtc aaaaaacgca cattatactg ttcacacgcg ctgataaaac
    32341 ctttcatcct gtattttcct tgaagatcgt cgatttttgt gatgaacaac agacgctgat
    32401 gtcctttttt tatcaaatat tctgctgcca taaaaccgac tttcacatca tctaaacaaa
    32461 tataagaggc atttaactct tcataagcag cattgatcat caccatcgga atgccttgtt
    32521 ctctcaaagc aacataaagt gctaagtttg ggttatactg attacttttc gtaggctcaa
    32581 cgatcaaacc atctacccca taagcaatca ttttcttcaa acactctttc tccaattcgt
    32641 gatcgttatt cgtactggct aaaagcaatg aatacccaga ttctcgtaat tcattttcga
    32701 ttcctcggat aatcgacgga aaaatataat cagagagata tgtggtgatg acaccgatcg
    32761 tttttgttct gttcaatggt gttttttctt tcttatagct gtcatctaca tatgtgcccg
    32821 accctttttc tttacgcaga tagccctcat ttaccaacac agcgattgct tgccgaatcg
    32881 tatgtctgct gacgtcatat atttcttgca gcttgaattc tgagggaatg gttgtattta
    32941 cttcgtattc ctcacgaagg atcttttgtt ttatctcttc tgcaatatct tgatattttg
    33001 ccatttgcct tgcccctttt tatttgtacg tacatatatc ataacgagtc tgcaaggttt
    33061 attcaagcaa aaatcaaggt ttcttgtgct cataaggcat acggaacagg ttcaccaaat
    33121 tctggaaatc cttgctcatt ccacgtaaag cattgcgcgt tcgcgtgccg attaggattg
    33181 tctaacggat cccctttttg gttcttctct ggtcgagcat gatagatcaa aatatcaaag
    33241 cacccgtctt ctgaaaccgt aaacgagttg tgaccaggac caaattgctt atttttttca
    33301 gaagaaacga atactggctc cgataattta tgccatgatt cttttaataa aagattcttg
    33361 tgctcatcag cccacagcag gcccatggca tagttttcat ctgttgcact accagaatac
    33421 gtaatgaata ttttcccatt gcgagtaagg actgctggac cttcatttac tgaaaaaccc
    33481 cgtttttccc attcatactc aggtatagaa aggaggatct gcttcccctt taacgtccaa
    33541 ggattatcca tttcggatag ataaagatta gaattcccag taatttcagg atcttgttgg
    33601 gcccacacat aatatagctt tccttgagaa gagaaagttg ttccgtctaa actgaaagtt
    33661 tcccttttcg tttttatttg tcccttttct atccaatctg tattcattgg atctatatgc
    33721 tgattttcaa gtacgaacat gcggtgatga tgagattcat cacgtatagt tttatgattg
    33781 cttgcagcaa agtaaatata ccattttcca ttgatataat ggacttcagg tgcccagatc
    33841 aattcactca tcggtccttc ttcatgagcc tgccatacaa tcaggcttgc agcatgttct
    33901 aattcattca gtgactttgc ccttcttaat tcaatcactt ggtagcctgg aaccgatcct
    33961 gtaaaataat aataaccatc tgtatgttta tatacccaag gatctgcccg ttgccgaacg
    34021 ataggattat tataaagtgt cttcatcata acaaatttcc tcacattttc tttattctaa
    34081 ttacattcca agagtatttt tctatcccta catttaattc gtcatgtttt tctattgaaa
    34141 aatagtttat ttcaggtttt attttttctg gttcttcacg tgtatttttg tccaacagat
    34201 cgctactggt taatgtgtag tgctctcctt gatctagcaa attgaaatca tgttcaatcg
    34261 ttatcttttg ttgttcattt gtgcgattga tcaagaaaat agtcagctga ttgccgttat
    34321 ctacgatcac actgtccaca taaggaacat tttttatctt ttcacaatca taaacagggc
    34381 aaatgatttg ttgtttcaat acttgacctt tagcatattt cgataagtgt tgcatcacat
    34441 aataagttgg attcctccat gcttgtcctt tagcatctgt cagtattaaa ggtattgtgt
    34501 ttactaacaa tgattgacaa ctaatcttta cgcgatctgc gtgtcgtaaa atagccagcc
    34561 ctaatgaacc aaataataat gtatcttcca tagtaaagta acaccaatcg atgggactac
    34621 cgacttcaaa atccctatgt cttttttccg gttgggcatg tacattccat tcatcaaacg
    34681 ctagatacat tgttttctca cttctcaaat atccttttac ataatcacaa gtagcaacga
    34741 tttcttcaat ttgacgatcg aatcgataag cttttgcaag gtatgtcgct gtatcatcac
    34801 gctcattttt aggaggttta gtcaagtctt cttcatcata cttatcaata tagttatgca
    34861 aagctaaata atctacattc tcataagctt cttctaatgc gatacgatcc cattcagggt
    34921 acgatggtaa acgtggcgta gagcttccaa ctaagattgt ttcaattgaa tcatccacta
    34981 acttcatgac ttttgaggct tcatttgcta acctaccata ttcataagca ctcttagccc
    35041 ccacttgcca tggaccgtct agctcattcc ctaaacacca taatttaacg ccaaaaggct
    35101 ttttttgccc attttttatt cttaaatcac tccagaaggt tccttttgga aaattacaat
    35161 attctactaa attttttgct tcatcaattc cttttgttcc taaattcacc gtgaatatcg
    35221 gtttcgcttg tacatgactg atccatttaa aaaattcgtg gagtccaaaa gaatttggtt
    35281 ctatacctcg ccatgctaaa tcaatttttt ttggtcgttg ttctttccta cctacagtat
    35341 ccacccaatc ataaccagat gtaaagtttc ctccaggata gcgaatgaca cctaattcta
    35401 attcctttac ataagagagg acatcttgtc taaacccgtc accatcagct gtttcatggc
    35461 ccggttcata aatccctgta tagacgacac ttcccatatg ctcaacaaat gagccaaaca
    35521 gccgagaact gatctctcct accgtaaaat cctctctgat ttttactttc acttcttcgt
    35581 ccaacagctt tccctacctt tcatttccta tagtcaagat aatagataca agtttccata
    35641 cgccaccagc aaagataaaa ataaaaggag ggaaaagaaa tatgagcagt acaaatccta
    35701 ataacaatac gcaacaaaga atatttctca aaaaatcaaa aaatactttc catgcacttt
    35761 gttcaaaaat ttgtaaaaat gtgatatctt tgttttcaga aatcacatat atccaggata
    35821 aaagaaacat ggaataaata agtaaaacta catatccact aattgaaagt acgattgtct
    35881 gttcttctaa taattgatta acaagaaaat aaataatgat cgttaacaga ctaaggaaca
    35941 agttcttacc aaaatgttgc tttattcctt gaaagaaaaa ataaatgata tttcctgatc
    36001 cctcaccttt ccattgcgcc attacataaa aaacagcaca tgtagcaggc acgatagtaa
    36061 taacaggcaa acacacgatt acccagagaa tacctaataa gatgtaatca gaaaccacaa
    36121 tcaactgtcc ataaaattta gtctcaacta ttttcatctt cctcactctt tcattccaga
    36181 catagctgtt ccttgaacaa aatatttctg tgcaaaaata taaaccacta gtaatggcag
    36241 cattgaaata accgttccag ccattacagg tccataaaaa gaaatgttct gccctgtaaa
    36301 taaagctaac cctgctggta aagttctcat ttttgaacta cttgtcaata tcaatggata
    36361 aagcaagtca ttccaactat tcatcagcgt gaaaatccct aatgataaaa gagtaggttt
    36421 gctcaatggc aacatgattt tcaaaaaaat attaaactca cttaatccat caatgcgtgc
    36481 tgcctcttcc aaagaatctg gtaaagtaat aaaaaaggaa cgcatcatga agataccaaa
    36541 tgcagttgtc atacgaggaa tgatcaaacc tgcataagta tcaagcatgc caagcaaatt
    36601 gacttcaata aatagaggaa tcatgaagac ttggaatggg atcatcattg tcagcaaaac
    36661 gaaatagaac aaaactgatt ttcctttgaa acgcatacga gcaaatgcat accccgcaag
    36721 agaatcaaag aatacagaag tgatcactgt ccctccagca aaaatcactg tatttttgat
    36781 gtaatctaat aaagggatcg ttgtccaaac cttaatatag ttatctaggg tatagctatc
    36841 tgcaaatatt ctaggcggaa atgagataat gtctttttcg tgtttaaaag aagaaataat
    36901 cagccacaaa aaaggaaacg caataaccaa caatataact agcatactaa tcgttcgaat
    36961 gattttttta ccactaactg cttttcgact attcacagta actgtaatcg agctttctgg
    37021 tgccatacag gtttccctcc tatttcattt gtttttcttt ccgtgacatg tacacattag
    37081 tggagatagc tatagttgca acaatgataa acaaaaccga agacagtgct gatgcatagc
    37141 ccaattcata aggtgctgta aatcctcgac tgtaaatata ttgaacagct gtttctgtct
    37201 taaattgtgg gccaccagcg gttgcaacat atacttggtc aaacacttgc atcgaaccaa
    37261 tcagattcgt taaaatacaa aaacctaagg agggaacgat ctgaggtagc gtaatgttaa
    37321 aaaactgctg tcgatttgtt gcaccatcca tttgagcaga ttcatacaaa gagggagaga
    37381 ttccctgaat agcagtcaag agaatcgtca tagtaacacc aaaattcttc caaacagtca
    37441 tgatggctac cgtcggcata gcaagggttg gatcgcgaaa aaattgaggg atcggcaagc
    37501 cgacttgtga aaacaagtaa ggaatcgccc ctacattcgg atcaagcaac atagaaaaaa
    37561 taatcgcaat tgacgtcaat gaacaaataa ctggaatgta aaatgtcgaa cgacaaaaac
    37621 gattgaatct ggtattttta gataatgcta ctgctgctaa taaaccaacg ataatttgtg
    37681 ttggcgtttc gagtacggtg aaatataaag aatgaatcaa cgaattaact gctcgttcat
    37741 cactaaatat acgtgtgaaa ttttcaaaac ttacaaaatt tcttgatgta aagaaaatat
    37801 tcaaatctgt aaaactaata gcaaatgttc ctaaaagcgg tatgacagta aataataata
    37861 aaactaaaaa agatggagtt aaaaacaaat acgcagcacg atcaggacga ttccaatatt
    37921 tggtgaatcc gttcatatag tccacctcat ctttcatttt gataaaatat acaatcttgg
    37981 tttaaacgaa tctgaataag atatccgaac aatcgctgtg atttttgcaa taacacctat
    38041 ctgcaaatac taggtcgatc attcagatat ctgtatcttg ccaacagtct atcctgtata
    38101 aagttctgta ctatttttgc agtaattgat tgatggcatc atctgcatcg ttcatgagtg
    38161 tctcaggatc ttctcctgct aataattttt caatcagtgg attgatgata tcgttattga
    38221 tcgcagagat ttgggtaaaa cctggtaaat atggctctgc atagtccatt tgtttcgata
    38281 attcagatac aataggatca ttttttactt cttcatcttt tgctactgaa tccaagtagg
    38341 caggaaaacc attttcgata ctccattttt taccaatttc agttgtattc caatatttca
    38401 aaaactcata gacagcttct tttttattat tatctgtact tgccggaatg gcatatccta
    38461 cgccatctaa aatagctgtt tttttgtctg aatcactccc ttgtggtaag gtagtcacat
    38521 tataatcaat ctcgtttgct ttcaatccgt tatttaacca tggcccattg atttcaatgg
    38581 ctagttgacc agcattcatt aaattgtcca tttcggcgcc agaaatcgat tctggaccag
    38641 tcttgtctac atggatcatt ttttggatcg cttttaacgt tttaaggttc tcaggagacg
    38701 caaattcaga cttagtataa tcatcgttca ctaatttacc gccatttgct aacatccagt
    38761 tatataacgg tgcagttcca tccttattga agacaaaacc tgatacattt ttactactat
    38821 cagttaattt tggtgccatt tctgtcaatt cttcccaagt agtaggtggt tgttcagtat
    38881 ctaatccagc ttgtttaaac aaatcattat tccaatacat atacatgcct tgtacctgca
    38941 tggggacaaa atactgttta ccttctactt cacctaattc aatagccgtt tctttaaaat
    39001 cagatttatc tactccatca tattcccaga aatcgtctaa tggttgtacc gctccgtttt
    39061 ctacatactg tgcaaaatct ggataattta atgcaataaa gtcaggtgct tttttagaag
    39121 aaatcgctgt aggaagtttt tcattcaaat tggcccaagt catgatatcc atttcaattt
    39181 tgatgttttt atcatttgtt ttattaaatt cattaacgat ttcttgcaat atttcaccat
    39241 cagatgcagt aaacccattc caaaaagtca aagtcacttc tttatcagaa tcagattctg
    39301 ctgaacttcc gccaccgcaa gctcctaaaa tacctgttgc agctaccaac aaagagccaa
    39361 ttaaccattt tttacctttc attttttgtt cctccttcat ctgataaacg acatctgacc
    39421 acattccaag atagcggttt caataaacaa ttgattttcc catcttcagc ttttacattt
    39481 gttgaatgac ttggttttac ttgttcactt ttaggaagat tagttgcttt tgtatcaaat
    39541 ccactcattt cagaaaaatc aatcactccc tctaatgata attcagacaa gtgaacagtt
    39601 agattcattt cttcttctcc acggttaact gcaaatatga caagttcttt gtcatttatt
    39661 acggctatac tttctaaata cggcacttct tcaaaatctt ccgtcgcata gtttgctgaa
    39721 cgaatttgtg ggcttaacac ctctccttgt ccatacacag cagcttgcat aaatggataa
    39781 tagatcgtct gtctccaagc ttctccgttt gtttctgtcc tgattggtgc aataacgttt
    39841 accaattgag caagacaagc aatctttact ctatctgcat gtttcaataa agtgattaat
    39901 agacagccta atagtaatgc atcttcaaaa ttatagttat cttctagtaa aggaggagca
    39961 atctgccaag gcgctgcttg ctcatcttgt tccgctgaat gataccaaat attccattca
    40021 tcaaaggaca ggttgatctg cttcttacta tgtttcttcg ccttgactgt atcgcacatc
    40081 gctgtcactt cagaaatgaa ccgatccatg tctaaggaac gtgcaagata atgagaaaga
    40141 tcattttttt ggttgccata atattgatgc agagacaaat aatctatttg atcgtacgct
    40201 tgatcaagaa ctgttaactc ccaatcacca aatgtaggca tttgccgatt cgaacttccg
    40261 cataaaacca cctcaattga atcatctacg agtttcatcg ccttagccgt ttcctctgct
    40321 aaccgtccat attcttccgc tgttttatgt ccaatctgcc aaggaccgtc catttcattc
    40381 cctaaacacc atgtcttaat tccaaaaggg ctctcttgac cattcgaacg ccttaaatca
    40441 ctccaataag ttcctttagg aaaattacaa tattcgacta aattacgagc tgcatctact
    40501 ccacgagtac ccagattgac agccatattg atttcggccc ccacatgctg acaccagtta
    40561 taaaattcat gaatcccaac ttcattcgtt tcaattgtcc gccaagctaa atccaacctt
    40621 ctaggtctat ttgctatggg cccaatactg tcttcccaac gaaatcctga cacaaaattt
    40681 ccaccaggat atctaatcat gggaatgttc aattctttta ccaagtgaat gacgtcttgg
    40741 cgaaatccac ttttattagc tgatggatga tctggctgat aaatcccttc atatactgct
    40801 cgtcccatat gttcaataaa tgaactgtac aaccgcggat caactttgcc tacacgcttg
    40861 acactactaa tcaacattgt ggcttccata actgacctcc tttaatttat acatgaataa
    40921 tacacctcgt tgaaagcgtt gtcaataata taaatgttaa acttacttat tttttatcga
    40981 ttttaattaa ccaaaatatt aataatgatt aaaacaaata atttaatata acttttatta
    41041 acaaatatgt taatatataa gaaaaacctt ttaagaggtg atatatatgc aactacaaat
    41101 aaacgaagaa tccttaccgg tatatgaagc attagctagt aaaacaagga tcaagatcat
    41161 ccagctactt tccaaaaaaa agatgaatgt caaagatttg gcaaaagaac ttggagtgag
    41221 cagtgctatc acgacgatgc acgtgaaaaa gctagaggaa gcaaacatca tcaaaacaga
    41281 aaaagtagga caacaaaaaa tttcgagcct tcgtgtcgat aaaatcgata ttagttttcc
    41341 agaaaaaata ttcaatgctt ttgatacgaa agaaacatcg atacctattg gtcactatac
    41401 aaattatgca attgaaccaa catgcggttt agctacgatc catgatttta tcgggaaagt
    41461 ggatgaacca cgctatttta tggatcctcg aaggatggat gcccgcattc tctggtttac
    41521 cagcggattt gtcgagtatc aggcacctaa ttttttaaat acagaggata cattggagat
    41581 gttggaagtt tctgtggaaa tttcttctga atttcctttt tcaaatgaca attggccttc
    41641 agatatcact ttcagcctaa atggtgtgga gctaggaaca tggacgagcc ctggagattt
    41701 tgctgatatc cgcggtaaat atacgcctga ttggtatcca gataatctta atcaatacgg
    41761 cttgctgaag acgatccgaa ttaccaaaca cttgacgaat atgaatggag aacccttgtc
    41821 aaacatcacg atcaacgaca tccctaaaga gcaagacact tggcatttgc gaatcgaagt
    41881 gaaagacgat gccaaacatg tggggggctg tactttattt ggtaaaggat tcggtaatta
    41941 cgatcaggat atcaaattaa aagtttacta cagctgatat ttttcttttc tattttataa
    42001 aacaaaaaca gccaatccct atgaagggac ggctgttttt gctttattgt tatttccaga
    42061 aatcatccaa aacggaaatt ggcaaatgtc gtttatgttg tgtcttgttc caccatgctt
    42121 cgattttttc ttgtgcttga gcgggaactt cttttccttc tagataatca tcaatttcat
    42181 tatatgtgac acctagtgcg acttcatctg caatcattgg tttcccatct tcaagatctg
    42241 cagtcggaat ttttgtgtat aatttttccg gtgcattcaa tgcttgaagc aattgtttcc
    42301 cttgtcgttt gtccaaacgg aataatggca aaatgtcggc tccaccatca ccaaatttcg
    42361 tgaagaatcc agtaatgttt tctgcagcat gatctgtccc taatacggct cctgctcttt
    42421 ctccagctac ggcatattgc gtaatcatac gttgacgtgc tttgatattt cctttgttaa
    42481 aatcgctgat tcccacacct gcttcgctta atacttgtac ttgtgcatca acagctggtt
    42541 tgatatttac tcgcagacta acatcgggct ggataaagtc aagagcagct tttgcatctt
    42601 cttcatctgc ttgttcacca taaggaagac gaacagcgat aaattgatag ttttcatctt
    42661 ttgtttcttc acgcatttct tccatcgtta gttgcgccaa acggcctgct aaagtagaat
    42721 cttggccgcc gctgatacct agtacaaaag ttttaagaaa cggatatttt ttcaaatatg
    42781 ctttcataaa gtcaatactt ttacgtattt cttcttttgg atcaattgtt ggtttgacac
    42841 ctaattcatt gataatttct gtctgcaggc tcatttattc tcctcctatg cttctgtatg
    42901 aagttctgct acgctttttt tcattcgttc catgatagcc attttatggt tccagcattc
    42961 agtagacaga tcgactgggt atttttgcgg attcaagtct cgtttatact cttcccatag
    43021 tgaatctaga ttttcttttg tatattcttt gatttcgttt agtgcaggta attcgtaaac
    43081 tctttttcct tcgataaaga tatcttgtaa aactgggcga gctgtaaagt ctcgaacagt
    43141 tttattgata aacgtatgca ctggatggaa catgaagata gcttcttctt ctcgagggtc
    43201 ttcatcccat aatgtcacgt agtctccttc agatttccca tcaaaatttc gagtgatgcg
    43261 ccacacttgt tttttccctg gagtagttac tttttctgca ttgcttgata acttgatcgt
    43321 atccatcatt tttccttcat catcttcgat cgatactagc ttgaatactg caccaagggc
    43381 tggctgatca taggctgtga tcaattttgt cccaacaccc catacatcaa ttttagcttt
    43441 ttgcatcttt aaattcaaaa tcgttgcttc atccaagtca ttcgaagcat agatttttgc
    43501 ttccgtaaat ccggctgcat ctaattgttc ccgaacacgc ttagatatat aggccatatc
    43561 tccactgtcg atgcgtacgc cttggaagtt gattttgtca cctaattctt tcgccacgcg
    43621 aatcgcactt ggcacacctg atttcaacgt atcataagtg tcgactaaga acacgcagtc
    43681 tttatgggtt ttagcgtagg ccataaatgc ttcataatca tttccataag attggactaa
    43741 cgaatgagca tgggtcccgc tagctggtat cccaaatatc ttcccagcac gtacattgct
    43801 tgttgcatct gctccgccga tatatgccgc tctagttccc cagactgctg catccagttc
    43861 ttgtgcccgt ctagttccaa attccaatag tggatcttct ccgatgacag atttgatacg
    43921 agctgctttt gtcgcgatca acgtttggaa attgaccata ttcaacagtg ctgtttctac
    43981 taattggcag tgcgctaaag gcccttccac ttggatcaat ggttcatttg caaaaactag
    44041 ttctccttca cgagcagaac gaactgttgc tttaaattca aaattttgta aatactccaa
    44101 aaaaccttca ggatagactt ctaatccacg caagtaagca atatcggaat cattgaacgt
    44161 cagattctct aaataattga ctaaccgttc caatcctgca aaaaccgcgt atccgtggtt
    44221 aaaaggcatt tctcgaaagt aacattcaaa aacagcatgt aaatcagctc gacctaattc
    44281 ccagtatgtc tgcatcatat tgatttgata tagatccgta tgcagcgtca aactgtcgtc
    44341 tgggtaagta ttattcatct tgtattactc ctcttggcaa gttttcattt cctacccatt
    44401 ataacaaaaa aaattaatag gaaaagaaat cttccatttt ttctgaaaaa gcacatgttt
    44461 tacggatatt tcttgctaaa aatgaactcc atctgctaaa actatccttt cttattggta
    44521 tttaacctaa acgagaaaga atacttattt tattcaatgt atccgagaca cgaagaaatt
    44581 agcgttttct atttttctta cttgataaaa taagtagatt ttcctactac aatcgtagcc
    44641 gttaagatac cgatgattga acaaatataa ccaaatgtct ctacaacata atcaatggca
    44701 aaagtttttg aagcaataat acgtctttcc ttttttgctt cttatcccca aagaaacgga
    44761 tataacttat tatgtattga atttttttgg aaaggcgaat tatgacaaga tataccttgc
    44821 gttgaaaaaa ctcgcggaaa aaatatcaca cgtttttaaa aagatacaaa gtaagaaagc
    44881 agctgtcaat agaatggaaa caaaaatggc gagacatcaa tcagtctcgc cttgtttttt
    44941 attgtataca ttagatatgg agcaggttac cataaagatg attattagtc gttattaaat
    45001 agaatccttc gtattttttt gttctatcac tacaatatct ttatttggac gtttgaattg
    45061 tattccggca cgttctagct cctgtttcac tcctacatgg actttgacat cttctcgtgt
    45121 catttttaaa acgtgatgaa tcgcatagtc gatttcttgc cttgtgattt ttttcttcgt
    45181 attgatcatc acgacttgct ttttatcata tgtgtctacc aatagcagtt gtgttcgatc
    45241 taacgaaaat aatttgtaat aattaatagc cgtattccca aaaaagaatt ccactacttt
    45301 aggataaaat gtcttaatat ttaaattact attcacaggt gtttcgatta gcttcatctc
    45361 attcctcttt tctatatagt cgatttagat ccaatcttaa gttatgttac catctttcct
    45421 agcattaagg aatcggttac aattgaacct ttaaagacaa aaggatttac cttttatcac
    45481 ttaatagtat aacataattt catgagaaaa aaatacaatt ttttcttgac catctcgtta
    45541 cgtaaaggat tatgcttaca tttgtcagga ggaaaaataa tggagtacac aataaagaaa
    45601 atgtcagaga tatcaggagt cagtccgaga accttgcgct tttatgatga gattggactg
    45661 ctaaaaccag ctaggatcaa ttcttcaggt tatcggattt atggcaaaaa agaagtcgat
    45721 cgtctgcaac acatcttatt ttatcgaaca atggcattca agttggatga tatccaagag
    45781 gtcttagaca atccatcttt tgaccaccag aaagctttaa tcaagcatca gcaaatgttg
    45841 ctggaaaaac gggcacaaat cgataccctc ttgacaactg tccaacagac acttgatatg
    45901 tacgaaggag gaagaaaaat gagtgacaaa gaaaaatttg aagggtttaa acaacaaaag
    45961 ttgaaagaaa atgaagaatc ctatggacaa gagattcgac aaaaatacgg aaaaaaaaag
    46021 gttacagcat ccaatgaaaa atggatgaat atggataaag aaacgtatga agaaatgcaa
    46081 actgttgaaa agcagatgtt atttgatctc actctttact taaaagaacc agaagatgaa
    46141 agcttagcag accgtatctt ccaagctcat aagaagtggt tatcttacag ctggcctgaa
    46201 tatcagccaa aagcgcataa aggactagga atgatgtacg aagccgatga acggttcact
    46261 gcatattatg acgagcgaag tggtcatggt gcagcaaaag ctttaaatga aattatccaa
    46321 aaaaaggcgt aatcttttac atgatccaac aaaaaagtac acgtaaaatg acctaataac
    46381 aaaacagcag acacccaagt tagattttta tgctaacttt tggtgtctgc tccattcttt
    46441 cacaagtttt ttcatcctac tttaaatata ttcatcgttg aataaacgta taaggtattt
    46501 tcactttatc ctttttttct gtaagaaaca attgaaatgc catttctccg caagcttcca
    46561 gatggtggtc gatggttggg aaaccaagaa gctcgctgat cagcaaatta tcgcgtccaa
    46621 tcaccactgg tgtcttatct tgcagatagc tttgcaagat gcctgctgca accatatccg
    46681 aatttgtaaa gacaccatca actccaagct ctttaaaaaa gaagcctgct tgttttcctt
    46741 tctctgcatc tatacaatcc caaaaaacaa gtgattcatc aaaagatgga aaaagttgat
    46801 gacatagctg caaagtgatt tttgagttat aacttagcct gccacttcgc cccaacgtga
    46861 tgcccaattg ctttatacct tgctgcttca aataagtaag accttctgta attgattgtt
    46921 ctcgatcaat aaagacacag cttgcctgtt ttcccttgat ttcttcacaa aaaactagag
    46981 gtccatattt ttgatatgcc aataaatcat ctagtgtatt ggcacgagac gtaatgatca
    47041 atccatcgaa agctttagct gcaaattctt caagatacct tcgctctttt tctttctgat
    47101 agcccgtcgg taaaagtgtc actttgtaat cataatcaaa cgctgcttca atgatcccac
    47161 tgatcaactg atcaaaatac ggatgattgg tataaggcag aatcactcca atgcttttcg
    47221 tttttccata acttaactgt ctggcatttg cattagggat ataatcgact tctttcatga
    47281 ccgcaagtat ttctttcctt ttttcctcat ctacatatgg atgtccattg attacacgtg
    47341 aaatagtaga aactgaataa cctgtgagct ttgcgatatc tcgaatgttt gccactgctg
    47401 cttcgccacc tatacaaaaa gattttcttg taaatagtct accacagctg gaccgcattc
    47461 aaaaaactga tacatttttc cttcatgcga aaaactgatc cgctgcccgc cccaatatat
    47521 atcttttgtc aaattttcga tttcattcat tggtatttct tttactatat tcctattcaa
    47581 cccttgaaaa ctgtacaacg ttaatacgga tcccttgaac tcgacaaacg cataaaaata
    47641 attgttcgtt gtgccatctg ttatctctac ataagtattc attgcaagcc ctccttttga
    47701 tactttgagt atagtgtatg aaacgcgtct catagcaagg agtttgtttt gccaaagaaa
    47761 agttttattc ctctttcatt attaccaaag tctcttattt taaattgaat acattataat
    47821 gatactgtaa atatatcttt attattagtg aatggatatt tacttttaat agataaaata
    47881 ttataactat taaaaataac tattttcatt ataattacac acaaaaaaga gcgtgagaca
    47941 aaagtaaaga acacttttgt ctcacgctct aaacacgtat aaacagcgga agcagaagca
    48001 actccttcgg aaataagctg aaattcacaa aaatttgaaa agcaatttcc gtgaatttct
    48061 tcttatttct tggagttaaa cgcttctgtt ccagcctctt tttatctgtc tttcactaat
    48121 gatcagttgt agataagcaa gttgcttttt cttacatcat accgcccatc attgatggat
    48181 ccattgcagg agctgctggc gctgctggtt ctggtttatc tgcaacgact gcttctgtcg
    48241 ttaataacaa ggcagaaacg gaagcggcat tttgcaaggc agaacgtgtt actttagttg
    48301 ggtctacgat acctgcttca accatgttta cccattctcc agtagcagca ttgaaaccag
    48361 tgcctagttc cacgttcttc aatttatcaa caatcactga tccttcataa ccagcgtttt
    48421 cagcgatttg acgaattggt tcttctaaag cacgaacaac gatcttgata cctgttgcca
    48481 cgtctccttc tgcttctaca gcagaaactt tgctgataac gttcactaga gctgtaccac
    48541 cacctgagac cattccttct tctactgcgg cacgtgtagc attcaatgca tcttcaatgc
    48601 gtaattttaa ttctttcaat tctgtttcag tagctgcacc aactttaaca acagctacac
    48661 cacctgctaa tttagctaag cgttcttgta atttttcgcg gtcaaaatca gaagttgttt
    48721 cagcaatttg gtttttgatc aattgcacac gagcttcgat tgcttctttt tctccagaac
    48781 cttctacgat cgttgtattg tctttatcta caacaacttt agaagcattt cctaagtttt
    48841 cgattgttgc atctttcaat tctaaaccta gatcgtcagt aattactgta ccacctgtca
    48901 aaatagcgat atcttcaagc attgctttac gacgatcgcc gaaaccagga gcttttacag
    48961 ctactacgtt gaatgttcca cggattttgt tcaatacaag agttggcaat gcttcaccat
    49021 ctacatcgtc agcaataatc aacaatggac gtgattgttg caagatttgt tctaacaatg
    49081 gcagaatatc ttggatgtta gagatttttt tgtctgtgat caagatatat gggttttcta
    49141 gaacagcttc cattttgtcg ttatctgtta ccatatattg tgataagtaa ccacgatcaa
    49201 actgcatacc ttctacaaca tctagttctg tttcgatccc ttttgattct tcgattgtga
    49261 tgacaccgtc gtttccaact ttttccattg catcagcaat caaatgtcca actttatcag
    49321 aacccgaaga aacagctgct acttgtgcaa tggcttcttt tgaatcaaca acagttgaga
    49381 tattatgcaa ttcttcgact gctgcttttg ttgccaattc gatcccgcga cgaatgccta
    49441 gaggattagc acctgcagtt acgtttttta aaccttcgcg aacgattgct tgtgtcagaa
    49501 cagttgctgt cgttgtaccg tctcctgcaa tatcatttgt ttttgatgct acttctgata
    49561 caagttttgc acccatgttt tcaaaatgat cttctaattc gatttctttt gcgatcgtca
    49621 caccatcatt tgtgatcaat ggagagccgt aagatttttc tagtacgaca tttcggcctt
    49681 taggtcctaa tgttactttc actgtatctg ctaatttatc taccccgcgt aacatagctg
    49741 cgcgtgcgtc ttctgcaaat ttcaattctt ttgccatgat tgattcacct cattgattat
    49801 ttttgattat ttttttatct tccaaattta ctcaacaatc gccatgatat cttttcctgc
    49861 gacgatcaga tattcttttc cttcgtattt tacttctgta ccggcgtatt tttcgaacat
    49921 aacttggtcg cctgctttta cagcggcagg aactttttca ccgttttcta acaaacggcc
    49981 ttcaccgact gcaacaactg tcccagtttg gggtttctct ttagcagcag aagctaaaac
    50041 gattcctccg acagtttttt cttcttcttt tgcgacttcg ataatgacgc gatcacctaa
    50101 tggttttaac acgataaatc cctccgataa ctcttttttt aatctgttag cactcttaac
    50161 cttcgagtgc taacctacat ttttaataat actcattctc cctctttttt gcaagctttt
    50221 aaatcaaaga aaagaaattt tattctgaca gctgcttatt gaaattatga tataattgaa
    50281 atcaatcgat ataagcttgc cttgcatgct tgttatccct taaaaggagg aattacatgt
    50341 ctttaaaaaa atatagcttc ctcagcattt tttgctatgg tctaattttt atctcaccct
    50401 tgatcctagc ttcgatagga cttgtaaaat ctacgtctga attgatcaca gcaactgcag
    50461 tcatgtatat actaggcgcc gttgtcctag ctatttttta ttttaagcaa cgtgaaccct
    50521 tagcgatcga atcagcggta aaaaaagctt ctgctccaaa gattgttatt tatggattgg
    50581 ttggaatctt tgtcgcattg attctgcaaa gcatcgctgt catgttagaa tctgtattgt
    50641 ttggcaaagc aaccccttcc gagaatacac aaaatatcat ccagatgatc atggaagcac
    50701 ccgcttttat tttggcgaca actgttgctg gacccatcat ggaagagttc gtattccgcc
    50761 gcagtatact ggggatcatc agtcgatatt caaatttttg ggtcggagca gtgatcagct
    50821 ctttgctgtt tgcgtttgct cataatgatg gtcatctgct aatctacttt ttcctaggtt
    50881 tcttcttcag cctagagtac aaagcaactg gtcggatctg gacatcgatg atcacacacg
    50941 taggaatgaa cacattagtt gttcttgttc aattagctgt ccaaaaaggg ctagtataaa
    51001 catgactata aatactcctg tcatcctaga ttggtgattt tcccaatcta aagcgacagg
    51061 agtatttttg ttttttagtc gttcatcttt tctgctgctc catcattttt tgtctgtctt
    51121 tcctttttgc agtttgcaga atctattttt ttcaaaaatg ggaaataaat gaaaaaacta
    51181 attgacaaca cgataccttg taaaatcgct gcaggcactc cgcctactaa gaaacccgag
    51241 aggatcggcg gtgttgtcca agggacttgg actgctgtaa ataaaggaac gaatccaaaa
    51301 tataaagcgg aataggtaat caatcctgaa acgaccggtg cgaaaataaa aggaacagcc
    51361 atcatcgggt tcatcacgat cggtgtggaa aaaataattg attcattgat gttgaaaaag
    51421 gctggtaaaa gagcaagatt tcctaattct ctgtatttct tcgatttcgc aaaaaccgtc
    51481 ataaaaaata cagcccctaa cgtcaatcca gcacccgtaa ccgtcatgaa ctgatcgaga
    51541 aattgctgag taacgatatg tccgccattt gccaccgtca actcttgtcc tgaggctaag
    51601 atttctgcat ttgctaatga attcgcttgc aagacgggac taaccaaccc attgaccatc
    51661 gcagatccat gaagaccaaa taaccataaa aacggaacaa aaaaacctaa taaaagcaca
    51721 ccaaacaacg tgtctatgaa cgattgaatg ggaagctgga catatgtcca tactccttga
    51781 acaacagtca ttctgaacaa atgttgaaaa accgctgaac cgataagcgt aaaagtgact
    51841 ataacaatga ttggaatcaa tgaagtaaaa gactgccaaa cattttcagg tatcttctct
    51901 ctttgcttcc accctttcgc aagtcttact aaacgtgcat agccccatcc gatgatgagc
    51961 ccagttgtaa ctgctcctag tatcccttca gcacctgtcc agacagtatc tatctgagta
    52021 tttagtggct gaataagcag tagataagca gacaaggctg ttatgccgac tggtaagcga
    52081 tcgatgtctt cttcttttgc ataagcgtat gcgatggcaa aaacgatcca aaaggctatc
    52141 acatcaaatg tagcctggta tacttgtgta aaatacatag aaaatcctgt tttgtctatc
    52201 cactgagcga tgtaatccac aggaaaatga gcaaataaga aaaacagcga gccaacaata
    52261 attattggga tcgtgtaagt cattccatta cgcaaagcag ttaagggtct aagattcaca
    52321 acagatgtta tcattggtaa aaaggcacga tctaaccact ctttcatttc ttatctcctt
    52381 caacttctat ttttatcaat cagttttctt aatttaacta tacccaatga tcacgaacca
    52441 tgaaaggaat gcgcactgag cttttcaaaa atcggattct ttgacgaata ttcagcaact
    52501 gcttacaatg gacaggaata aaaaaggagg ttttttatga aaattgcact cattggagct
    52561 actggccatg caggttcatt tattttagac gaagcattgt ccagagattt agacgtgacg
    52621 gcaatcgtgc gtcatccaga aaaattgcca tcagatgttc cgtttataca aaaggattta
    52681 tttgagttga caactactga tcttgcatct tttgatgttg tcgttgatgc tttcaacgct
    52741 cccaaaggaa aagaagaaat gcatcaaact tctttgtccc atttgattga gatgcttgaa
    52801 ggaaccgata cacgcttaat tgtcgttggg ggtgcctctt cgttattctt agatacagaa
    52861 aagacgactc gtatgattga ccaagtacct aaaaatgcac ccttctatcc aacagctttc
    52921 aatatgtacg aaggattgtt aaaattgaaa caatctaaaa atctacattg gacttatatc
    52981 agtccagctt ctttatttga tccacatggc aaacgtacag gtacttattt gttaagtgat
    53041 gattatttac aaagaaacgc tgctagcgac agtacgatca gcatggcaga ttacgcgatt
    53101 gcattagtag atgagatact ggatgagaaa catgaaaagc agcacatcag tgtagtcagt
    53161 cgataatacg gttatttttt taatatgcta aaaaaataaa aatagaagat aaaaccaacc
    53221 ctgattgatt ttatcttctg ctttttatat ttttattgat tgaactgttt aaatcgaaaa
    53281 tagctcagtt gcttcatctg gatctgtatc atagatttca aaatcatgtc caacgccaaa
    53341 atctttttct ttcaaaacat tttccattgt taaatgagca agttctttca tattgttttc
    53401 cttgctaaga tggccaagat agattcgttt ggtccgatta ccgatcacat cagtcatgac
    53461 aagtgcaccg tcttcgttgg aaagatgtcc tctatctcct aaaatacgct gttttaaatt
    53521 ccacggataa ggtcccatgc gtaacatctc aagatcatga ttactttcca tcaaataacc
    53581 atcggcattt tcaatgacac ctcgcatata atcactgcaa tatccggtgt ccgtcaacat
    53641 gacgaatgac cgattttctt tatggaaacg ataaaattgc ggagccgctg cgtcatggga
    53701 gacgccgaaa ctctcaatat cgatatcgcc gaatgttctg actttcccca tctcaaatag
    53761 atgtttttgt tccactggta catttccaat cagtggttcc atcgcttccc aagtctgctg
    53821 attggcaaaa acatccaaat gatacttacg agccaagaca cccacgccat gtatatgatc
    53881 tcgatgttca tgcgtcacaa gtattccatc taattggtcc ggtgtccgat caatttgagc
    53941 catcaaggaa gtgatttttt taccgctaag tcctgcatcg accaaaagcc gttttttttc
    54001 actttcgata taaagtgaat tacccgaact tccacttgct aggatactga ttttaaaagc
    54061 tggtttttct tcagccattt gactcctact tcccttctta ctttgtaaac ttttttcatt
    54121 atactcgctt ttttattgat cttccacttt tggtacagta ttgtttgtca cgatcgtatt
    54181 gctgaaagcg ttgacgctct caatttggac cactttatcg cttgtttcga tcgctacatg
    54241 ccaaacagga acatacacat ttttttcccg gactttcaga atacaggaat aagctagctg
    54301 acgccataaa atttttgatc ctcttggtat tttgttattg atgtacaatg tattgattgc
    54361 ttcctcttcc gtatacagtt ccgtcttttc gcgcagctgc tcgatatcag ataaatgcgt
    54421 ctgcatgtat ttcgtgatgc tataatcatt atcgtttttt tctaaagaaa gaacgatttt
    54481 tgctgtatca tcattgaatg ggatgccttc atactcttgg cttgcttgga tttctagtgg
    54541 ttcttcttct aaatgagaaa agtttttcgt gtacacataa tcattaccga ataaaatatt
    54601 gtctttgtta gataaaaaat cttccaagga actactaatt ttatctggat cgatcacgtt
    54661 cttttcagca tctgaactgg ataaagattt cgtcaaaaca tcaccgtcta aaaacacacc
    54721 acttgccagc aagccgcttt taccagcctt gcgataattc gctaatgaag tgctaagatt
    54781 ggtctgctcc gcgctaagat aatagccttg cttgttctca gacgaaatct tccccgtgta
    54841 agtgatatcg tcgctagcca gacgttgttg gattgattca gtctgattag agcgaatgac
    54901 attgttttct tggtataccg cgtcatgata actgctgaat aaaaacacat tcaaccctaa
    54961 aaaagcgacg aaaaatatcc attcgatttt tttgaaatcc aattaattcg cctccaatcc
    55021 aggtaatttt tccagaaggt cgttagctga ataccagtta tctttatatt tcacatacca
    55081 ttcaggtaag agatcaacga cacgattcgt ttctttgaca ttttgccatg tatagccaac
    55141 gatcactgaa ccaatcttgt tgctatctgc tcccttagct tttaactgct ggatgatttc
    55201 attcgtactt gcaagttcta cttcttcgtc tgaaggtatc ggcacttgaa tcgtattcaa
    55261 actggtttgg atattcactt gcacagaacc attcgtttca ccgccaactt ccacaccaat
    55321 ctgtcctctg ctgtctgtcc caaaaaccgg gaagccttcc acgaatatcc gataatcgat
    55381 cgtattgtca ctgcggtcaa aatatctgag gttccctaaa gaactgccta atttgctaat
    55441 ataggggaaa ctttcagaaa atacactagc attttctttt ttctctggca gctctccacg
    55501 aaaatcaact acttgcgttt ccgaatggat agacattgtt tcattcccac cgtaaaaaat
    55561 caattcattg ctttcatcat tatttttcac gctatctggt ttctggaaaa aagcatttct
    55621 aaaaagtgta tagggttgct gtgacaggat ataactatac ttcttcagtt tgatcgaatg
    55681 tttcgtagca tattgcgtgt cgatcgtcga tggttctgtt gtcatttctg tccattttgt
    55741 gtcttttgct gttaattctt tattgatatc tgtccaattc aacgaaatat ttgcttcata
    55801 tacgagatgg ttcgaataat tcaaaaatcg gattttttta tttccttgat cgaattgtat
    55861 tctagtaaaa tacatatttt cgctttcttt tgccaagttc gacacatcta aatctaaatc
    55921 aaatgcttcc ttgtattctc ttagcaaaaa aggcgcatta taggccaact caaaaccaga
    55981 gttcagattt ttcacctgtt caaactgtga tttgtctcct gaaactactt cagaaagctt
    56041 tccaaatctt gctttatcga tgatcaattg caatcggtac acgagatttt cactgttggt
    56101 ttcttggatc attcccgaat ggtgccatgt aacatgaagc ggaagaaaga cttcggaagt
    56161 ttttcgattg ctttgagact cgatcatttg agtgtttgtc tcatctacgt tgattgaact
    56221 ttttcctgct gggctcagcc agattgcata agagaagtat atgcttaacg caaccatcaa
    56281 aatgagtcct atacgaacga ctttttcaga gattctcatt cccaccattc ctcctcataa
    56341 ggttcatatg gcagcgagat ataaaaagtc gacccttttc cttccttgct ctctgcccaa
    56401 atagcgcctc gatgcgcctt aatcacttct ctagaaatag ctaatccaag tcctgtccca
    56461 ccttgtgctc ttgcacgtgc tttatctact cgatagaacc gctcgaacac tcggttcaga
    56521 tcttttttag gaatccccaa tccttgatcg gtgatactta aaatcacgtt attatgcgtt
    56581 tctaataagc gacaagtaat cgttccccca tctggtgaat acttgatcgc gttattcatg
    56641 atattatcga ctacttggat gattttatct gtatctactt cgacccaaag atctctttgc
    56701 gtaaattcac gacggatctt ataatttttt tcctgatttc ccaccatcat atcaaaccgg
    56761 tcaagaacaa aattcactaa ctcgttgaaa ttgacatatt ctaattgaag ctgggtatta
    56821 cctgtatcca tgcgagatag atttaagagg tcattgatca ttcgaatcat tcggtctgtt
    56881 tcatctagcg ttaccttcaa aaaatttggt gctacttcct cgtctttcca cgcaccttcg
    56941 ctcaatgctt cgatataact acgcatactt gtcaacggtg tacgaagttc atgggaaaca
    57001 ttagagacga attcacgacg ttcccgttct gttttttctt gttctgtcac atcatgcaag
    57061 acagctacta atccgctgat aaaacctgat tcgcgacgga tcatagaaaa gtctactcgc
    57121 aagatcatct gatcactttc caatgtactg gttgaacggt caagtaccat ttcgtttgga
    57181 tcttctaata atttccgcaa cgtatattct tcttcgatat ctaaaagtgt caaaatcgat
    57241 tgtccgattg cttcctcgtt tttgatatct agcaaggaaa cagccatatc attgatcgta
    57301 atgactttac ccctgcgatc tgtcgcaatg acgccgtctg tcatatggga tagcacgcta
    57361 tccaaacgat tgcgttcagc ttccattgta tcttgagctt cttcaatacg ttcagctaac
    57421 tgattgaagg tatcagccag ctgtccaagt tcatcttgtc catgcacttt gactttccga
    57481 ctgtagtctc ctctagcgat tcgaatggct tgttctctca tttcaccgat cggctgtgta
    57541 atcgaacgag caactaaaac agatacgatc attgaaataa atgccgcaat tagtgaggca
    57601 gtaaagaaaa tgactgctgt gttattgatt tccgaatatt tttgttcgat attacttttg
    57661 acgtaaaggg ccccgataac ggcatcgccg gtcggggaca ggatcggttg aacattgata
    57721 ttcacccgtt tatcgtcgtt atctaaagca acataacgtt tagtcgtgaa atcattgata
    57781 tcaacataat catttttctt tcccacagcg ctttgttcat tgacatcggt tgttcctcgg
    57841 atgatccctt tttcgtcaac gacccgtatt tcgatgatat cgctagtcgc actgttttca
    57901 ataaatcttt tgatattcgc atttacctct tcatcatctg cattatcttt tcgattcaat
    57961 tccgggctga ttgttgttgc taatgattcc accgtttgat tcatatcttt aataaatgta
    58021 ttgatcgtgg aacgttctaa accacgtata aagtaggcac caataatttc gatcgagatc
    58081 aataaaatca gaataaaggt aatagcgatc ttaaaattga ctgatcgaaa aaagcggact
    58141 tttcttttca tccaattact cctgttctgg gttacgcaaa tagtaaccga caccacgacg
    58201 tgtcactaaa taatttggat ggcttggatt atcttcgatc ttttcacgca aacgacgtac
    58261 agttacatcc actgttcgta catctccaaa ataatcataa ccccaaaccg tttgtaataa
    58321 atgttctctt gtcatcactt gtccaaggtg cttcgccaag taaaagagta gttcgaattc
    58381 acgatgtgtt aactcgattg tttctcctcg tttcgtcacc atgtaagctt ctggatggat
    58441 cgtcaaatca ccaatcgtca attccgcagg tgctgcctct tctggttcct tcgcagccgt
    58501 ggcaccgcga cgaagatttg ctttgacacg tgcaactaat tctcggttgg aaaatggctt
    58561 ggtcacgtaa tcatcggcgc ctaactctaa gcctaggact ttatcaattt cagaatcttt
    58621 ggctgttacc ataatgatcg gcatatcata agttttgcgt acctcacgag caacttctaa
    58681 gccgtccatt ttaggtagca tcaaatcaag taaaatcaaa tcaggttcta cctcagcaac
    58741 tttttccaag gcttcttccc catcatatgc agtataaacg tcatagcctt ctttggctaa
    58801 attgaatttg acgatatccg aaatcggctt ctcatcatcg acaactaaaa cttttttcat
    58861 aaagagccac ctcttatata ttattgtcat accttctcat tataccgtat ttctgctttt
    58921 gtttcatctt tgcctataaa acaaaagaga aaattaaaat gaaagtgcaa aatactttat
    58981 tattttttgt tctaacttca ataaaaaagg aaaacactga ttttcacctc agtgtttcct
    59041 ttttttgatt tatccttcta aaacttgtac accgacaccc aataatcccg gaccagtgtg
    59101 gactactaat gccggagaaa tctggccaaa gtagatttgg tttgcttgtg ggaactctct
    59161 tttaagtctc gcttccattt caattgcttc ttctttcgca tccccatggg caacagctaa
    59221 gttgaagacc tttgcattac cgattttttc tttgacgtaa gcaaccgttt tatccaaact
    59281 ttttttacgt cccctagctt ttcctactgt gtaataaatc ccttcttcat tacatgagat
    59341 gattgggtta agctttaaag cggttcctac aatagaagca actaaaccga tccgtccacc
    59401 tttttgaaga tattccaatg tcgcaacatt aaagaaaact tttgttcttt cgactaactc
    59461 attcagatta ctgatcagtt gatcccattc tactccttct tccagccatt ttgctgcttg
    59521 gatcgcagaa aaacctgcac caataccaat atttttcgta tctagtacat atgcttccaa
    59581 ttcttcttgc tgttgtgcaa ttaaacgaac cacattatat gtcccgctca atccactgga
    59641 aattgttacc gcaagtacct tttcataacc gtcttttttg atttgctcaa agatttctgt
    59701 gatcgactca ccatccggca aagatgtacc agggatttcc tctggcaaac gttgatagat
    59761 ctcttcaggg gtaatgtcaa ttttatctgt atatacctga tctttataaa taattttcaa
    59821 tgggatcata tacatctcgt atttttttat caattcttct ggaacatccg tacctgaatc
    59881 tactaaaatt gcgattttat tgtttttcat ttgttttctc ctcttttaaa tattcggttt
    59941 ctagaacaat cgttttttcc gcaagaagtt tcattgcaaa cgataaagtt gccgctctta
    60001 cagcaatata ttctacaggg gttgcctggt cgaatttttg cggatgagat ttaccttgtg
    60061 ctaattggct gaccatccac acagctgctt cttgttcatc gcaaaataga ttataggctt
    60121 cacgaattcc tactgttttt ccttggaaca atatcccttc tttgatttca ggaatagtca
    60181 atacttgttt caacgtagtg attgcaagta aaaatgctac gtgttctttg ttatatcttt
    60241 ttttaactgg tgctggtatc aaacctagtt taacgtaatt gtttaccata gaagaggtaa
    60301 gcaatggatg cttttctcct tgtatcacag gtgaaagata acgatcaact aacgttctga
    60361 cttggtccat ataaagttct aagtcaggga gttcttccca gtgaggcaga cggaatgttt
    60421 ctagttcctt cccccactcc attaattgct gacgcatttt ttccatcata accgctcctt
    60481 ttttcatttc ataaacatga tatcagactt atgataaaca ttcaatctag ttgctttaac
    60541 taggtgattt gattagcggg attccatgaa aacaaaaaac aagaaggcta agccttcttg
    60601 tcttttatcg ttaagaacag gagacccgcc ggggagacgg cgggaaagga gtaaaaa
//
LOCUS       DAPBAF010000012        60165 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.012, whole genome shotgun sequence.
ACCESSION   DAPBAF010000012 DAPBAF010000000
VERSION     DAPBAF010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 60165)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 60165)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..60165
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.012"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            195..267
                     /locus_tag="RD451_000868"
     tRNA            195..267
                     /locus_tag="RD451_000868"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:228..230,aa:Lys,seq:ctt)
     gene            complement(763..1149)
                     /locus_tag="RD451_000869"
     CDS             complement(763..1149)
                     /locus_tag="RD451_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HDT7566151.1"
                     /translation="MNKRKTEFILILISGITGILCSLLALMGGMFLSSIDSTTLNTTE
                     LTSKDIDMLVNLSGNVVLFGGITLVFSIMIFIIGFLVRKNQKTVVYGISLLILSIIPF
                     FLLTLLWVIPGVLGIIAGLMLLIRKS"
     gene            complement(1146..1667)
                     /locus_tag="RD451_000870"
     CDS             complement(1146..1667)
                     /locus_tag="RD451_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HDT7566152.1"
                     /translation="MNKKSGIETLPNYVFAGFWLRFFAFLIDLICISIITHATIGLFY
                     KIMGLESDKSIITFYGIASLAIYLTYFVLLTKLNSGQTIGKMIFGIRVVSFEEKELSW
                     QTIFIRECICRFILKNFVFQIGYLVAAFTPKKQHIGDYFSNTSVVVIRSLEAINYGQK
                     ISNSKTLNLERIK"
     gene            complement(1669..2703)
                     /gene="sppA"
                     /locus_tag="RD451_000871"
     CDS             complement(1669..2703)
                     /gene="sppA"
                     /locus_tag="RD451_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HDT7566153.1"
                     /translation="MNKRRWIAVGVACGLLLLSIIVALIPGKDKEEASNTTLTGINKI
                     FYGSNEITEETLEEGASNKKIVKLSVNGVIADTGESNLFSREQYNHQNFLTQLKKIQE
                     DKAVKGVLLEVNSPGGGIYESAEIAKEMAKIKKLDIPIYTAFKNTAASGGYYISAGSD
                     KIFATEETTTGSIGVIISGLNYSGLLEKLGVTDATYKSGALKDMMSPQHKPSEEENKV
                     IQEFVMSAYDRFVNVVAKGRNMDTNAVKELADGRIYDGNQAVENGLVDQIGYSEDALD
                     SLKKEKKLTDATVIEYKNDTTGFASSWLGNKIAEWQGLKATTSDRVISVFEKLGFSDT
                     PKPMYYYGGL"
     gene            complement(2736..4151)
                     /locus_tag="RD451_000872"
     CDS             complement(2736..4151)
                     /locus_tag="RD451_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HDT7566154.1"
                     /translation="MVSIKNYGKSRRGKQFMQNNNWFEHSSIYTKQHHSFYRWVLYPV
                     ILFLCIIGLFLTFAKKEVVIRTTAQLNPEKIEKLQVPLEAKIMENFLKENQFVHKDDV
                     LVRLDCSLIENEKAQIEQENQRITQQIKMAQLFIESISKGKNLFSTDDSFGYSNQLKS
                     MLSEKESLRYALKQSELNDQKQLEVYEKTKRQLEKQIESSDSKLQEWQQVQVAWSNNQ
                     SLKDFSKEMMANYENWQEQLNNVSDDQKNQVKLTISASINEQIEQLKKEVEQYQSEKA
                     KLVKPTTSENDRISQTEKGKQELEQAITTVKQTVTELNEKQEKNQSVIKSLDDQLSKG
                     ILKAPVSGTVHLNEETKGQAELAKGTVLAEIYPIHEKSKMKFTALLPANESTYIKEGM
                     KVHFKLDQKGGAPITIDGTLDEISENSTATEKGVFYAVKGTLKTTQSFPFRYGLTGEL
                     SLIVGEKTYWQQIVDVFLNKK"
     gene            complement(4120..6273)
                     /locus_tag="RD451_000873"
     CDS             complement(4120..6273)
                     /locus_tag="RD451_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HDT7566155.1"
                     /translation="MIKSFPFVQQQDEKDCGVACLSMILKYFKTDIPIHKLRDLSGTD
                     LEGTSAFGLKKTFEKLSFDCMAIQADSEIWKERDLILPLIAHILVDNSYMHYVVIYKT
                     KGNVLWIADPANGKNRKTIEAFQKEWTGILLLPMPRETYIPIKEKVAGLSSFLPIIWK
                     QKGLVFHIVLASIFITFFGIGSSYYFQGILDFFIPNQARSTLNIISIGLIAVYLFRVL
                     FEYSRSYLLIILGQRMSMAIMLQYFKHVLTLPMNFFATRKSGEIISRFLDASKIIDAL
                     ASATLSIFLDIGMVLLVGVTLAIQNSTLFLITLCSLPFYVVAIFAFVKSYEKSNREEM
                     AAGAAVNSSIIESLKGIETIKAYSGEEKVYNRIDHEFVKLMKKSFRTVTLDNIQQGIK
                     HLIQLISSALILWLGSYFVMDNRISLGQLITYNALLVFLTDPLQNIINLQVKMQTAQV
                     ANNRLNEIFAIDSEKSNQSFEYMLSEQLFQQDITVKNVSFSYSMKAPTLNEISCTIPS
                     HSKTAIVGVSGSGKSTLAKLFVRFYEASEGSIHYGNINHLDIPFQILRDRVTYLPQES
                     FFFSGTIIENLIFGLDSPPSFEQIIEVCEIVQLNEFINQQPLRYETLLEEGGNNLSGG
                     QRQRLALARALLKNPDILILDEATSGLDTLLEHAIMNYLLNLKEKTIIFIAHHLPIAK
                     ACDQILVLHEGHLVEKGTHDELRFADGIYQKLWEI"
     gene            6531..6767
                     /locus_tag="RD451_000874"
     CDS             6531..6767
                     /locus_tag="RD451_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HDT7566156.1"
                     /translation="MFKHAKCKGTKYCGNAQTVGGGNNAWGKLGQVVGGLTTGAVGGA
                     GLGTAICGPACGVVGGLYGAVAGGAAAGWDARKK"
     gene            6786..7001
                     /locus_tag="RD451_000875"
     CDS             6786..7001
                     /locus_tag="RD451_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HDT7566157.1"
                     /translation="MHIKNTKTTFILSSEELKNIQGGSAVGVLGTTFSGATAGVKLCS
                     AGGPYAIAACGVGGALLGAGFSMWTGA"
     gene            complement(7704..8456)
                     /locus_tag="RD451_000876"
     CDS             complement(7704..8456)
                     /locus_tag="RD451_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7566158.1"
                     /translation="MSYPIILCEDQIIQLNQLERIIDNFILFHDKVFKIVLKTQSPLE
                     VKKYLKQFRPKQGIYFLDIDLNHEVNGIELAEVIRKYDVQAKIIFTTTHDEMLPVTIK
                     RRVETLGFVTKDQTLDEYRNEIVELLLLAQERIDATKQVTNQAFVFSIGSQTFTFDIN
                     DIYFVEASKLPHRLSLCTKDGQYEFYGRISELEKKYPMLTRISRACLVNIFNVKEIDF
                     KKRSLYFDSELARNFTLGKAQKIKEKLKESTV"
     gene            complement(8471..9718)
                     /locus_tag="RD451_000877"
     CDS             complement(8471..9718)
                     /locus_tag="RD451_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HDT7566159.1"
                     /translation="MFVGNFFFFLLFYMTNTDLNKRKYLFVCLLIPLTFFVELFTDVS
                     AAIPIIGSYFILKEKKKTNIVLLNKLLLCMLIDDFRSIITSMVMTYMFSFEGIKGYGY
                     VVFQIMLDSLFLLMFIWLYRKLAINRIVEQSSSKLTAIFMIYLLTIGLFVSYVAHQYQ
                     VFDHFVFGVLIFLIIQMFVVLFLFIRITIRQREQYEQQLKRKELVYLKKYTDSLEKDQ
                     EKFARFRHDYKNLLLSLKEIANQNHDSILEKEIKELEIYSNSYLTNKFEYRYLKNIKN
                     EYLKSLLIAKLYQANNNKICCKFECPSTIIEVPVPIFDCIRVLGIILDNAIEASIESQ
                     DRELSLAIYRDDKQIEISISNSCREILLSIDTLMKKGITTKKGHQGLGLSSIEEINKK
                     NPNMFVNYQNDPYQFTTQVILLF"
     gene            complement(9794..9940)
                     /locus_tag="RD451_000878"
     CDS             complement(9794..9940)
                     /locus_tag="RD451_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EntF family bacteriocin induction factor"
                     /protein_id="HDT7566160.1"
                     /translation="MEEKNRLNAKQCSDQELKKIKGGAGTKPQGKPASNLVECVFSLF
                     KKCN"
     gene            complement(10044..10355)
                     /locus_tag="RD451_000879"
     CDS             complement(10044..10355)
                     /locus_tag="RD451_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HDT7566161.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLKLEKQKYE
                     LDPGPLINRLVNYLYFTAYTNKIRFTEYQEELIRNLSEIGRTAGINGLYRADYGDKSQ
                     F"
     gene            complement(10357..10554)
                     /locus_tag="RD451_000880"
     CDS             complement(10357..10554)
                     /locus_tag="RD451_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HDT7566162.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            complement(10948..12675)
                     /locus_tag="RD451_000881"
     CDS             complement(10948..12675)
                     /locus_tag="RD451_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HDT7566163.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(12668..13861)
                     /locus_tag="RD451_000882"
     CDS             complement(12668..13861)
                     /locus_tag="RD451_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HDT7566164.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRNLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(14048..14692)
                     /locus_tag="RD451_000883"
     CDS             complement(14048..14692)
                     /locus_tag="RD451_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDT7566165.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(14786..14920)
                     /locus_tag="RD451_000884"
     CDS             complement(14786..14920)
                     /locus_tag="RD451_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HDT7566166.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(14922..17054)
                     /gene="feoB"
                     /locus_tag="RD451_000885"
     CDS             complement(14922..17054)
                     /gene="feoB"
                     /locus_tag="RD451_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HDT7566167.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(17051..17524)
                     /locus_tag="RD451_000886"
     CDS             complement(17051..17524)
                     /locus_tag="RD451_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HDT7566168.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            17925..18149
                     /gene="nrdH"
                     /locus_tag="RD451_000887"
     CDS             17925..18149
                     /gene="nrdH"
                     /locus_tag="RD451_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HDT7566169.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            18308..20467
                     /gene="nrdE"
                     /locus_tag="RD451_000888"
     CDS             18308..20467
                     /gene="nrdE"
                     /locus_tag="RD451_000888"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HDT7566170.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFLSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYAMAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            20517..21482
                     /gene="nrdF"
                     /locus_tag="RD451_000889"
     CDS             20517..21482
                     /gene="nrdF"
                     /locus_tag="RD451_000889"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HDT7566171.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(21571..22710)
                     /locus_tag="RD451_000890"
     CDS             complement(21571..22710)
                     /locus_tag="RD451_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDT7566172.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAV
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(23019..23732)
                     /locus_tag="RD451_000891"
     CDS             complement(23019..23732)
                     /locus_tag="RD451_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HDT7566173.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(23986..24687)
                     /gene="nagB"
                     /locus_tag="RD451_000892"
     CDS             complement(23986..24687)
                     /gene="nagB"
                     /locus_tag="RD451_000892"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HDT7566174.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            24921..26453
                     /locus_tag="RD451_000893"
     CDS             24921..26453
                     /locus_tag="RD451_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HDT7566175.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(26644..27846)
                     /locus_tag="RD451_000894"
     CDS             complement(26644..27846)
                     /locus_tag="RD451_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDT7566176.1"
                     /translation="MKSNEKKPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMAALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTVFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQTVVFKG
                     KRNLENKK"
     gene            complement(27928..28617)
                     /locus_tag="RD451_000895"
     CDS             complement(27928..28617)
                     /locus_tag="RD451_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HDT7566177.1"
                     /translation="MKKKIIRLILISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(28723..29091)
                     /gene="rplL"
                     /locus_tag="RD451_000896"
     CDS             complement(28723..29091)
                     /gene="rplL"
                     /locus_tag="RD451_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HDT7566178.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(29144..29647)
                     /locus_tag="RD451_000897"
     CDS             complement(29144..29647)
                     /locus_tag="RD451_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HDT7566179.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     misc_feature    complement(29851..29978)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(30057..30746)
                     /gene="rplA"
                     /locus_tag="RD451_000898"
     CDS             complement(30057..30746)
                     /gene="rplA"
                     /locus_tag="RD451_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HDT7566180.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(30850..31272)
                     /gene="rplK"
                     /locus_tag="RD451_000899"
     CDS             complement(30850..31272)
                     /gene="rplK"
                     /locus_tag="RD451_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HDT7566181.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            31615..32283
                     /gene="sdaAB"
                     /locus_tag="RD451_000900"
     CDS             31615..32283
                     /gene="sdaAB"
                     /locus_tag="RD451_000900"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HDT7566182.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            32296..33168
                     /gene="sdaAA"
                     /locus_tag="RD451_000901"
     CDS             32296..33168
                     /gene="sdaAA"
                     /locus_tag="RD451_000901"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HDT7566183.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(33259..34278)
                     /locus_tag="RD451_000902"
     CDS             complement(33259..34278)
                     /locus_tag="RD451_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HDT7566184.1"
                     /translation="MEAGAFGYIRGGSEDEWTMKENTTSFNTKKIMPRILRGIDSADL
                     HTSVFGIELDTPIIQAPSAAQGLAHEKGEADTAKGVAAAGSIFSISTYANTTIKDAAD
                     AAPGAPQFFQLYMSKDDRFNEFILNKAVEAGAKAIILTADSTLGGYREEDVINQFQFP
                     LPMPNLAAYSEQSASGNGEGKGIAEIYAAAKQGLTPDDIKTIKEITHLPVIVKGIQSP
                     EDAVIAISAGADGIWVSNHGGRQLDGGPASFEVLPKIAEVVNKRVPVIFDSGVRRGEH
                     VFKALASGADLVAIGRPVIYGLNLGGAEGVTSVFEHLNKELSITMQLAGTKTIDEVKN
                     TKLMD"
     gene            complement(34451..35356)
                     /locus_tag="RD451_000903"
     CDS             complement(34451..35356)
                     /locus_tag="RD451_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HDT7566185.1"
                     /translation="MERKRCMTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEV
                     SDKEKTAESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDG
                     QIQATGDLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSM
                     GGVSALRYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQ
                     DYQQMIGNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTG
                     ENASHSMLHENQEVDQLVSRFIWKE"
     gene            complement(35415..35960)
                     /gene="nusG"
                     /locus_tag="RD451_000904"
     CDS             complement(35415..35960)
                     /gene="nusG"
                     /locus_tag="RD451_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HDT7566186.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(36061..36231)
                     /gene="secE"
                     /locus_tag="RD451_000905"
     CDS             complement(36061..36231)
                     /gene="secE"
                     /locus_tag="RD451_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HDT7566187.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(36255..36407)
                     /gene="rpmG"
                     /locus_tag="RD451_000906"
     CDS             complement(36255..36407)
                     /gene="rpmG"
                     /locus_tag="RD451_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HDT7566188.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            36569..37213
                     /locus_tag="RD451_000907"
     CDS             36569..37213
                     /locus_tag="RD451_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HDT7566189.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(37269..37772)
                     /locus_tag="RD451_000908"
     CDS             complement(37269..37772)
                     /locus_tag="RD451_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HDT7566190.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(37785..37831)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            38369..39334
                     /locus_tag="RD451_000909"
     CDS             38369..39334
                     /locus_tag="RD451_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HDT7566191.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGDDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(39433..40605)
                     /locus_tag="RD451_000910"
     CDS             complement(39433..40605)
                     /locus_tag="RD451_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7566192.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMPTIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(40592..41737)
                     /locus_tag="RD451_000911"
     CDS             complement(40592..41737)
                     /locus_tag="RD451_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7566193.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(41751..42675)
                     /locus_tag="RD451_000912"
                     /pseudo
     CDS             complement(41751..42675)
                     /locus_tag="RD451_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            42792..43871
                     /locus_tag="RD451_000913"
     CDS             42792..43871
                     /locus_tag="RD451_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HDT7566194.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            43903..44496
                     /locus_tag="RD451_000914"
     CDS             43903..44496
                     /locus_tag="RD451_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7566195.1"
                     /translation="MTKSLQTILESTKEIRVLGIGHCAKDALVLYETHRPDVLLTDIR
                     MPKQTGIDAAKEILAKFPKAILLLLTTFKDEEYIREAFSIGVKGYLIKQNLQAIIPSV
                     KSAYNGQAVFGNEIIETFTQMMKNKPTIDSHAYASFSERELAIIKEVAAGKNNKEIAD
                     ALYLSDGTVRNYISQLLEKLDLRDRTQLAIYFYQHLQ"
     gene            complement(44606..44833)
                     /locus_tag="RD451_000915"
     CDS             complement(44606..44833)
                     /locus_tag="RD451_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDT7566196.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(44936..47524)
                     /locus_tag="RD451_000916"
     CDS             complement(44936..47524)
                     /locus_tag="RD451_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HDT7566197.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(47544..48203)
                     /locus_tag="RD451_000917"
     CDS             complement(47544..48203)
                     /locus_tag="RD451_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HDT7566198.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVAQHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(48252..48755)
                     /gene="trmL"
                     /locus_tag="RD451_000918"
     CDS             complement(48252..48755)
                     /gene="trmL"
                     /locus_tag="RD451_000918"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HDT7566199.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(48976..49842)
                     /locus_tag="RD451_000919"
     CDS             complement(48976..49842)
                     /locus_tag="RD451_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HDT7566200.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            49951..50592
                     /locus_tag="RD451_000920"
     CDS             49951..50592
                     /locus_tag="RD451_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HDT7566201.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(50654..52015)
                     /gene="mgtE"
                     /locus_tag="RD451_000921"
     CDS             complement(50654..52015)
                     /gene="mgtE"
                     /locus_tag="RD451_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HDT7566202.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(52033..52932)
                     /locus_tag="RD451_000922"
     CDS             complement(52033..52932)
                     /locus_tag="RD451_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HDT7566203.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(52934..53731)
                     /locus_tag="RD451_000923"
     CDS             complement(52934..53731)
                     /locus_tag="RD451_000923"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HDT7566204.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(53709..54413)
                     /locus_tag="RD451_000924"
     CDS             complement(53709..54413)
                     /locus_tag="RD451_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HDT7566205.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            54544..55120
                     /locus_tag="RD451_000925"
                     /pseudo
     CDS             54544..55120
                     /locus_tag="RD451_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
     gene            55238..55915
                     /locus_tag="RD451_000926"
     CDS             55238..55915
                     /locus_tag="RD451_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HDT7566206.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
     gene            complement(55994..57802)
                     /gene="pepF"
                     /locus_tag="RD451_000927"
     CDS             complement(55994..57802)
                     /gene="pepF"
                     /locus_tag="RD451_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HDT7566207.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
     gene            complement(57978..58976)
                     /locus_tag="RD451_000928"
     CDS             complement(57978..58976)
                     /locus_tag="RD451_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HDT7566208.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            complement(59202..59855)
                     /locus_tag="RD451_000929"
     CDS             complement(59202..59855)
                     /locus_tag="RD451_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HDT7566209.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
BASE COUNT        18293 a        12270 c        10206 g        19396 t
ORIGIN      
        1 aaaaaatgaa aaaagtgtta gggtttgttc tcttgcaaga actttgtttg ttggtatgct
       61 tatataatag cgagcaaatg tgaataatct atgaatgatt tcctataagg aagtaaagat
      121 ttttctgatt ttctttaaat gtagtcttgc attttaaaat tcttagtgct actattatta
      181 agtacttttt gtacgggccg ttagctcagt tggtagagca gctgactctt aatcagcggg
      241 tcgcgggttc gagcccctca cggcccattg ggtgccaaac ccacggaaca ggtaaatgtt
      301 ggtgcgaaag catttcgaaa acatttacgc tgttcttttt ttatttttca aaataactag
      361 ggctttttat ttttaactca aagtccactg tagccctttg gactttgagt taaaaaagaa
      421 gcataattat gaacagtaaa gtttctaata taacaataat tcgagaagct ttgcaaaatc
      481 atgctgccaa tgaactctct aaacatatag gattaaatct aagtactata aaaggttaaa
      541 aagtgaagaa tatttaatag aaaaactaaa tttacttgct gctttcccct tttccattaa
      601 tacaacaatc agagagtgtc tttttttcga aaaaattaga ataaataaaa gacacgtagt
      661 ttttttatct acatgtcttc catcgactac aagttatcat ttctcaaaac gtatttagct
      721 tttaattgat taatcgtttc acgttgtcta cacattgcct aattaagatt ttcttattag
      781 aagcatcaat cccgcaataa tacctaaaac tccaggaatt acccacaata atgttaaaag
      841 aaaaaatgga ataatagata aaatgagtaa actaatacca tagaccactg ttttttgatt
      901 ttttcttact aaaaaaccta ttatgaaaat cattatcgaa aaaactaggg taattcctcc
      961 aaataaaaca acattcccgc ttagattgac taacatatct atatccttac tggttagttc
     1021 tgtagtattt aaagtagttg aatcaataga agatagaaac ataccaccca tcaatgctaa
     1081 aagactacat aaaatccctg ttattccact aattaaaatc aaaataaact ctgtttttct
     1141 cttattcatt taattctctc cagattaagt gttttagaat tagaaatttt ttgaccatag
     1201 ttaatagctt ctaatgaacg aataacaacc actgacgtgt tagaaaaata atccccaata
     1261 tgttgtttct tgggcgtgaa agcagccacc aaatacccaa tttgaaatac aaaatttttt
     1321 aatataaacc tacatataca ctcacgaata aagatagttt gccaacttag ctctttttcc
     1381 tcaaagctca ctactcttat cccaaaaatc attttcccaa ttgtttgtcc tgaattcagc
     1441 ttagtcaaaa gtacaaaata ggttaaataa atagctaatg acgctatacc ataaaaagta
     1501 ataatggatt tgtcagattc cagtcccatg attttgtaaa agagacctat agtagcatgg
     1561 gtgatgatgc taatacaaat taaatcaata agaaaagcaa aaaatcgtaa ccaaaatccc
     1621 gcaaatacat aattaggcaa agtttcaatg ccactcttct tattcatttt atagccctcc
     1681 atagtaatac attggttttg gagtatcaga aaatccaagt ttttcaaaaa ctgaaattac
     1741 acgatctgat gtagttgcct ttagcccttg ccattcagca atcttattac ctaaccaaga
     1801 agaagcaaag ccagttgtgt catttttata ttctataacc gtcgcatcag ttaatttctt
     1861 ctcttttttt agggaatcta atgcatcttc agagtaacca atttgatcca ccaacccatt
     1921 ttctactgct tggttaccat cataaattct tccatccgca agttctttca ctgcattagt
     1981 atccatattt cttccttttg ctacaacatt gacaaaacga tcataagcac tcatcacaaa
     2041 ttcctgtata actttattct cttcctctga aggtttgtgt tgaggtgaca tcatatcttt
     2101 taatgcacca cttttatacg tcgcatcagt tacgccaagt ttttctaata agccagaata
     2161 atttaaacca gaaataatga caccaattga tccagttgtt gtttcttccg tagcaaatat
     2221 tttatctgaa ccagcagaaa tgtagtaccc tccacttgcc gctgtatttt taaatgcagt
     2281 atagatagga atatctagct ttttaatttt tgccatttct ttagcaatct cagcactttc
     2341 atatattcct cccccaggtg aatttacttc taataacact cccttaaccg ctttgtcttc
     2401 ttgaattttc tttagctgtg ttaaaaaatt ctgatggtta tattgttccc tactaaaaag
     2461 attgctttca cctgtatctg caataactcc attgacggat agtttgacaa tctttttatt
     2521 tgatgcgcct tcttctaacg tttcttctgt gatttcgtta gatccgtaaa aaatcttatt
     2581 tattcctgtt agggttgtat ttgatgcttc ctctttatct tttcctggaa ttagcgcgac
     2641 gataatggat agtaacaata atccgcacgc tactcccaca gcaatccatc ttcttttatt
     2701 catataaact cctcctatat tcttagtaaa aataattatt ttttatttag aaacacatcg
     2761 acaatttgtt gccaatatgt tttttctcct acaattaaag acaactctcc agttaatcca
     2821 taacgaaacg gaaacgattg agttgttttt aacgttcctt tcactgcata aaaaacacct
     2881 ttctcagtgg cagtagaatt ttctgaaatt tcatctaaag ttccgtcgat cgtaatcgga
     2941 gccccacctt tttgatccaa tttaaaatga accttcatcc cttctttaat ataggtactt
     3001 tcattcgcag gtaaaagtgc tgtaaatttc atttttgatt tttcgtggat cggataaatt
     3061 tctgcaagca ctgttccttt ggctagttct gcttgtccct ttgtttcttc atttaaatga
     3121 accgttccag atacaggagc ttttagtatt ccttttgaaa gttgatcgtc caaacttttg
     3181 ataactgact ggttcttctc ttgtttttca tttagctctg taactgtttg ttttacagtt
     3241 gttattgctt gttctagctc ttgctttcct ttttccgttt gactaattct gtcattctca
     3301 gaagtagttg gtttaactaa tttagctttt tctgactgat actgttctac ttcttttttt
     3361 agttgctcaa tttgttcatt tatgcttgct gaaattgtca gtttcacttg atttttttga
     3421 tcatcagaaa cattatttag ttgttcttgc caattctcat agtttgccat catttctttt
     3481 gaaaaatctt ttaatgattg attattactc caagctacct gtacttgttg ccattcttgt
     3541 aatttactat ctgaactctc aatttgtttt tctagttgtc tttttgtctt ttcgtatact
     3601 tctaattgct tttgatcatt taattcactt tgcttcaaag cgtagcggag tgattctttt
     3661 tctgacaaca tgctctttaa ttgattactg tagccaaaac tgtcatccgt tgaaaacaaa
     3721 ttttttcctt tacttatact ttcaataaat agctgagcca tctttatttg ttgagtaata
     3781 cgttggtttt cttgttctat ctgagccttt tcattctcta ttaaagaaca atccaatcta
     3841 accaacacat cgtccttatg aacaaattga ttttctttta ggaagttttc cattatttta
     3901 gcttctaatg gcacttgtaa cttctctatt ttttcggggt tcaattgagc cgttgtccga
     3961 ataacaacct cttttttagc aaaggttaaa aacaatccaa taatacataa aaaaagaatt
     4021 acagggtata acacccaacg gtagaagcta tgatgttgtt tagtatagat actagaatgt
     4081 tcgaaccaat tattattctg cataaattgt ttccctctcc tagatttccc ataatttttg
     4141 atagatacca tcggcaaaac gaagttcatc gtgcgttcct ttttctacca aatgcccttc
     4201 atggagaact aaaatttgat cacatgcttt tgctattggt aaatgatgcg caataaaaat
     4261 aatcgttttt tcttttaaat tgaggagata attcataatt gcatgttcta acaaggtatc
     4321 taatccacta gttgcttcat ctaaaattaa tatgtccgga ttttttaata aagcccgtgc
     4381 taaggctaat cgttgtcgtt gccctcctga aagattattt ccaccttctt ccaacaatgt
     4441 ctcgtaacgt aatggctgtt gattaataaa ttcatttagt tggactatct cacaaacttc
     4501 tattatttgt tcgaaacttg gtgggctatc taaaccgaat ataagattct caatgattgt
     4561 tccactaaag aaaaatgact cttgaggcaa atatgtcact cgatcgcgta atatctgaaa
     4621 aggaatgtct aagtgattaa tgtttccata atggatcgat ccttctgatg cttcataaaa
     4681 acgaacaaat aactttgcaa gagttgattt tccagaacca ctaactccaa ctatagccgt
     4741 tttactgtgc gaaggaattg tacatgaaat ttcgttcaac gttggggcct tcatgctata
     4801 cgagaatgaa acgtttttta cagtgatatc ttgttgaaat aattgttcag aaagcatata
     4861 ttcaaaagac tggttcgatt tttctgaatc aatcgcgaaa atttcattta aacgattatt
     4921 tgcaacttga gccgtttgca ttttcacttg taaattaata atgttttgta aaggatctgt
     4981 caaaaatact agtaaagcat tgtatgtgat aagttgacct agactaattc tattatccat
     5041 aacaaaataa gaacctagcc ataaaattaa tgcactgcta attaattgaa tcaaatgttt
     5101 aattccttgt tgaatattat caagcgtaac cgtacgaaat gattttttca ttaatttaac
     5161 aaattcatgg tctatacggt tatatacttt ctcttcaccg ctatatgctt taattgtttc
     5221 tattccttta agactttcta tgatactaga atttacagct gcaccggctg ccatttcttc
     5281 cctgttcgat ttttcatagc ttttcacgaa agcgaatatt gcaactacat aaaaaggcaa
     5341 agagcataga gtgattaaaa acaacgtact attctgaata gctaacgtaa ccccaacaag
     5401 caacaccata ccaatatcta aaaatattga taacgtagca cttgctaaag catcaataat
     5461 cttactggca tcaagaaaac gagaaataat ttcccctgat tttctcgtag caaaaaaatt
     5521 cattggtaaa gttaacacat gtttgaaata ctgaagcata attgccatac tcattcgctg
     5581 tcctaaaata ataagaagat aactacgact atattcaaac aatacccgaa ataaatagac
     5641 agcgatcaag ccaatggaaa ttatatttaa agttgaacgt gcttgattag ggatgaaaaa
     5701 atcaagaata ccttgaaaat aatatgagct tcctatgcca aaaaacgtaa tgaaaatcga
     5761 tgctaaaacg atgtggaata ctaatccttt ttgtttccaa attataggca aaaaagaact
     5821 taatccagct actttttctt taataggaat ataagtttct ctaggcatag gtaataaaag
     5881 aatacctgtc cattcttttt gaaacgcttc aatcgttttt ctattttttc cattagcggg
     5941 atctgcaatc catagtacgt ttcccttcgt tttataaatt acaacgtagt gcatatagct
     6001 gttatcaacc aatatatgtg caattaatgg taagataaga tctctttctt tccagatctc
     6061 actatctgct tgaatagcca tacaatcaaa agacaatttt tcaaatgtct ttttcaatcc
     6121 aaatgctgaa gtaccctcta aatcagtccc agataggtcc cgtaatttat gaatcgggat
     6181 atcagtttta aaatatttta aaatcatcga aaggcaagca acaccacaat ctttttcatc
     6241 ttgttgctgc acaaaaggaa atgattttat cacttatcta acacaactcc ttctaaaaaa
     6301 tttttataga aaaattctca atatagcttt aatacagtga aaatattgtc tcataattcc
     6361 acaaaaactt tgaaaacagt tcttgaacac taactttttc attcctgaat caaatttatt
     6421 ttggaaattt tactattcaa gaataaactt gataagtttc aggaagattt ttactgttaa
     6481 tcaaatacgt atgttacagt agcaccgtaa aaaatattat ttaaagaagc gtgtttaaac
     6541 atgcaaaatg taaaggaact aagtattgtg gaaatgcaca aactgttggt ggaggcaata
     6601 atgcttgggg aaaattgggg caagttgtag gtggacttac cacaggggca gtaggtggtg
     6661 caggtttagg aacagcaatt tgcggaccag cttgcggtgt tgttggaggg ttatatggag
     6721 ctgtcgctgg aggtgctgca gctggctggg atgctcgaaa aaaataaaaa aggagaataa
     6781 gtagtatgca tattaaaaac acaaaaacaa catttatatt atcttcagaa gagttgaaaa
     6841 atattcaagg tgggagtgcc gtgggagttt taggcactac tttttctggg gcaacagcag
     6901 gagtaaaact ttgttcagcc ggaggacctt atgcaatagc tgcttgtggt gtaggtggag
     6961 ctttattagg tgctggattc agcatgtgga ccggtgcgta aacaattaaa aaatatcaaa
     7021 cctcaagatt ggtttgtgtc gattacgaac ataggtatgt tctttatctt ttcaaaagtt
     7081 tggaatggac agaacttttt actaaagctt cttgtgctag tttttataat tatattaaat
     7141 ttttatcttt tattaaagtc agataaaaat tctttggaaa tgtaatggta gagatatttt
     7201 tacaaaagga cttgcagcgc tgtagttggt gctgcaggag gacctatttc ggccgttaca
     7261 ggaggtattg gtaatgtact tgtcggatgt gcattaaagc ctgttcctgc aagttaaatt
     7321 tataaaaaca ggaaagtaat tatctcaaat cctatcaagt acaatcatag gattgcactt
     7381 gacaggacaa attttttaac taaaaaatga aaaacacttt ctaaaaatta gtagaatttg
     7441 ccaaatcttt cgcatcttcc accatacatt taattttaat tcccctttat ggtacttaat
     7501 aaaaacaaga aaagaactat tcatttggcc cttttttggt tccagaccat agaaatattc
     7561 ctccagtaac taatattgct gttatgcacg taactaataa cagctataaa aattggtaca
     7621 actttaatag gattcagaaa aatttgcact agtgaaggaa tctattttat tagaaaaatg
     7681 caatctccct aaagaaaaaa ccactaaaca gtgctttctt tcaacttctc cttaattttt
     7741 tgtgctttcc ctaaagtaaa gtttctggcc aactctgaat caaaatatag tgaacgtttt
     7801 ttaaaatcta tttctttaac gttaaagata tttactaaac acgctcgact aattcttgtt
     7861 aacataggat atttcttttc aagctcacta attcttccat aaaattcgta ctgcccatct
     7921 ttagtacaca atgataatct atgtggtaat tttgaagctt ctacaaaata aatgtcattt
     7981 atatcaaaag taaatgtttg agaacctatg gaaaaaacaa atgcttgatt cgtaacctgt
     8041 tttgttgcat ctatcctttc ttgcgctaat aacaataact caacaatctc gtttcgatac
     8101 tcatctagtg tttgatcttt tgttacaaat cctaacgttt caactcttct ttttattgtt
     8161 acgggtaaca tctcatcatg agtagttgta aaaatgattt ttgcttgaac atcatatttt
     8221 ctgattactt ctgctaattc tataccgtta acttcatgat ttaaatcaat atctaagaaa
     8281 tatattcctt gctttggtcg gaattgtttg aggtattttt taacttctaa cggactttgt
     8341 gttttcaata ctatcttaaa tactttatcg tgaaaaagaa tgaaattatc aataattcgt
     8401 tctaactgat ttaattgtat aatttgatct tcacataata ttattggata actcataaat
     8461 cctccttccc tcaaaacaac aaaataactt gagtagtaaa ttgatacgga tcgttttgat
     8521 agttcacaaa catattggga ttctttttat tgatttcctc tatactagat aaacctaacc
     8581 cttgatgtcc cttttttgtt gttattcctt ttttcattag agtatctata gagagtagta
     8641 tctctctaca actattcgat atcgaaattt ctatctgttt atcatctcgg taaatagcta
     8701 gagacagttc tctatcttga ctctctatag atgcttcaat tgcattatcg agaataattc
     8761 caagcaccct aatacagtca aatattggaa caggaacttc aataatagta cttggacatt
     8821 cgaatttaca acaaatctta ttgttatttg cttggtatag cttcgctatc aacaaacttt
     8881 tcaaatattc attttttata ttttttaaat aacgatattc aaacttattg gttagataag
     8941 aattagaata gatctctaat tcttttattt ctttttccaa tatcgaatca tggttttgat
     9001 tagcgatttc ttttaaactc agcaataaat ttttatagtc atgtctaaat ctggcaaatt
     9061 tttcttgatc tttttccagt gaatcagtat atttttttag ataaaccaat tcttttcttt
     9121 tcaattgctg ttcatattgt tctcgttgcc taatagttat tctaataaat aaaaatagaa
     9181 caacaaacat ttgaatgatt aaaaatatta agacaccaaa cacaaaatga tcaaatactt
     9241 gatattgatg agcaacataa gaaacaaata aaccaattgt aagtaaataa atcatgaata
     9301 tagcagtaag tttagaactg gactgttcaa caatcctatt tatagctaat tttctatata
     9361 accaaataaa catcagcaaa aacaaagaat caagcattat ctggaatact acataaccat
     9421 acccttttat cccttcaaat gaaaacatat acgtcataac catggaagta ataatagatc
     9481 tgaaatcatc aataagcata cataatagta atttatttaa aagcactata ttagttttct
     9541 tcttttcctt taatataaaa taacttccga ttataggtat agctgcggaa acatcagtaa
     9601 ataattcaac aaaaaaagtg agtggtatca ataaacatac aaaaagatat tttcttttgt
     9661 taagatcagt attagtcata taaaataaga gaaaaaagaa aaagtttccc acgaacattc
     9721 ttaatagata agcttttgta tcgatagtaa tcaagagatc ccctcctgat tttaggatat
     9781 cataaaaaaa attttagtta cactttttaa ataatgaaaa aacacattcc actaaatttg
     9841 atgccggttt tccttgaggt tttgttccag cacctccttt aattttttta agctcttgat
     9901 ctgaacattg tttagcattt agtctatttt tttcttccat tacgattccc cctacaaact
     9961 ataaatactt ttatgtcact gattcaatat acctattttt ctaatcaaaa aattttgaga
    10021 catatttaat attataagta tcattaaaat tgagatttat ctccataatc tgctcgatat
    10081 aaaccattta ttccagcagt tcttccaatt tcactcaaat ttcttattaa ttcctcttga
    10141 tattcagtga atcttatttt attagtataa gcagtaaaat atagataatt caccaatcta
    10201 tttattaaag gaccgggatc taattcatat ttttgttttt ctaattttaa atataccttt
    10261 tgtaaaacct caagaatatc agaatattta ggatctttac ttatagatat atcattatat
    10321 aattcatgaa caatttgctt agcatttttt ttcattttag cacttccctg gaattgctcc
    10381 acctaaaaaa ccacctatag acattcctgc aatacaagta gttgccttgg cccaatcgac
    10441 cgtacattta tttttagtgc aatacactcc atttccataa tattttccac tatgagtggt
    10501 acccccatag ataagttgtg tctctttaat agacaaaatt tttaaatgtt tcataatcta
    10561 atcaccccta aattaatgtt tttagactat tattctaaca ttcattaaat ttcaaaaaac
    10621 aattccttct tgaaacgtag caaaataatt cctgaataag aatttaatca cttttaagta
    10681 tataaactat gtatattctt taatattttt tgagaatgca cttcgtacat aataaacttt
    10741 aatcacatta gtctttcata cctacgatcg atctctttga ctcgcaccca taaattcata
    10801 atagtttgtc ggcgtctttg gacgtttcga agatgagcta cgcattctct ttttttatag
    10861 acaaaaaaga tagagacgaa catggagctt ccaaatttgg atatttgatc caattttgga
    10921 agctccattt atttcgtgtc tgtcttttta ttttttccag ctttcgacta attcttggtt
    10981 ctctttgatc cagtcttttg ctgcttgctg tggatctttt ccattgttga tttccaacat
    11041 aactttttcc atatcttttt ctgaccaatg gaaattgtct aatactttgt aagcttctgg
    11101 ctggtcttct ttcaatcctt ttcgaaccat cgtatggatc tgctcttcgc ttcccattcc
    11161 gttttcagga tcttctaagt atttcagatc atatttggca aacatccaat gaggtgtcca
    11221 tcctgtaact acaattggtt cgtgtttttt gatcgcttga cctagtgcaa cggtcattgc
    11281 tcctgaagaa gatgtctcta ctttccagtc tttcaagttg tcatattttt ggatcgtgtt
    11341 ttcagcagcc gtaactacac cagctcctgg ctcgattcct atgattttct tacctgcctg
    11401 atcggttaac tcatcgatcg aatttacatc catgtaggct ggcactgcta aaccaacttt
    11461 tgctcctgtc aaattggcac ctaggtcttc gacttgatct ttatattgtg catattgtga
    11521 accatgagtt ttaggtagcc aagctgaaac catggcatct gactcgccat ttgaaacaga
    11581 tttccacatg attgaattat ctaatggcgt catcgttaca tcatagccca tttgtttcaa
    11641 tacttcaccg actacatttg ttgaagcaac ttctgtatcc cattcaacat aagataagtt
    11701 gatacgtttt gtttctttgg cagatgaaaa actccctata ccaatcgcac ctaagatcac
    11761 tactactaca gcaccaatga tcagtccttg acgtttttta cttttctgtg ttgttgctcc
    11821 tgcagctttt ttattgtttg gctggttcaa atgctgtgta aaacggtcaa tgatgattgc
    11881 taagataact aatgcaaccc cgttgacaaa tccattcccg acttgtgctc tttgcaatgc
    11941 tgataatacg ccgcgtccta agccgggtgc accgatcata gaggcaataa cgaccattga
    12001 aagtgacagc attgttgttt gattgatccc tgccatgatc gtacttttag ctaaaggcaa
    12061 ttctagtttg aatagttttt gacgacttgt gctcccgaat gaatcagaag cttctactaa
    12121 ttctttagga acttgtcgaa tccctaaatt cgtaaaacga acggttggtg gcagagcaaa
    12181 gatgactgag gcaaataccc ctggaaccat cccgataccg aaaaatgcaa ctgctggaat
    12241 caaataaacg aatcctggca ttgtctgcat aaagtcaagg atcggtttga taatactttg
    12301 ggctttactg ctttttgcca tcaagatccc taatggtacc ccaatgatga tcgagatcac
    12361 actagataaa agaacaagtg tgacagtatt catcaaatca ttccatagac cttggttata
    12421 aataaaccat agaccgatta atgtgaacaa cgtaagtcct ggacgtttct tagaaataaa
    12481 gaaagctgct accgtcaata acaagataaa caaaggagct ggaatcacta acagtaaatt
    12541 tgtaatcccc gacatcactg cctgtccaat cgtttgtaaa aatgaaaata ggccagaaaa
    12601 agttgtcgta aaccattctg tgatattttc tacccagttt gccactggta attgatagtt
    12661 caatagatta ttcatgttca ctcacctcgc ttgtttctgc taatgcttca atcacactac
    12721 ctcggatgac gacacctttt aattttccat cctctacaac tgcaagtgga gtcggtgagt
    12781 cataaataat attgaaaata tcacttacca ccatgtcttt cccaatcacc gtcacatttt
    12841 catctaggaa gtcgatcaat ggacgttttt gcttcctagc ttctaacgct tgatctgcag
    12901 tgatgatccc tttcaggttt ctctttctgt caacagccat cagcatgctg acttcttcat
    12961 tacgcatcct tgtcaatgca acgtttggtc catcagattc gatattcgtc gtcaatgcag
    13021 gtaccatgat gttttgagcc gtaagcactt tggaacgatc gacttcttcc acaaattcac
    13081 gtacataatc atttgctgga ttggtcaata tttcttcacc tgttccgatc tgcatgattt
    13141 cgccgtcttt catcaaggcg attctgtccc caatccgtaa agcttcattc aaatcatggg
    13201 taatgaaaat aatcgttttt tgaacattgg cttgcaggtc cagtaattcg tcttgcattt
    13261 ctcgccggat cagcggatca agagccgaga acgcttcgtc catcagcaag atctcaggat
    13321 catttgctaa agctctggct aggccaaccc gttgttgcat cccaccagat aactgactag
    13381 gatattggtc tttaaatgaa agcaaactag aattttctaa tgctttttct gctttttctt
    13441 gtcgttcttc tttaggtaca ccacggactt ctaacccgta ttctgtattt tccaagatcg
    13501 ttcgatgtgg aaacagaccg aagttttgga aaaccatatt gattttatga cgacggactt
    13561 ctcgcaattc ttctttgctt aacttcgata catcttctcc atcaatatag atactgcccg
    13621 aagttggctc aatcagacga ttcaatagac ggatcaatgt ggatttccca ctcccggaaa
    13681 gccccatgat cacgaagatt tctccttctt ttacgtcaaa attcacgtca tacacaccaa
    13741 ccgttgcacc ggttttcttt aaaatctccg ttttcggctg gtgatcattc atcatatcta
    13801 aagcggcttg tgtcttttta ccaaatatct ttgttaaatg ttttacttct acttttacca
    13861 aacaaattct ccttttttat gtaaattcat ttttctttct gaaaaaagtg accacactat
    13921 gttaacatca tgtagtcact ttgtcaaaaa tgaaagaaat ttgcttgtcc aaactgaaaa
    13981 aaacttggct aaatctttgt aaataaaagg tttagccaag ttaatatttt tttaatattt
    14041 cacacaatca ttctgcaagc tgatgctccg ggtaaaaaaa gtttgtcata cgctgtagtg
    14101 tatattcatt tccaataaaa tgaacgatgt cccctgccgt aaatttagca taggggccag
    14161 gtgaaacaag cagttcttca ttatgagaaa ttgcgataac tgtggcgcca gtcgcctgcc
    14221 agatattcaa ctcgctaatt gaacggtcca gatgcattgc tttttctgat aaagataatt
    14281 caaacggaag taaaggattc atcttatgta ttcgcttcgt ttgattgacc agctgatcca
    14341 ataattgaga aaaatgattc agctcatctt gttgcttctc cacacttgcc atgatttctg
    14401 cttttgtatc ttggatggat tgtacatctt gatattgcaa taggaaatct tttgcttttt
    14461 ccttcgaagc aacaaatgcc ccacttccat gccgtacttc catgattcca agatctacca
    14521 gcacattgat agccttgcgg gtagtctcag gagaagcatt gtacgtactg gcaagtgttg
    14581 agcgggcatg gatcttctca cccactttat atcggttttc aacgatacgt tcggctaaat
    14641 caacagcaat ctgctggtag cgcgggcgga cgattttttt ctttccagac attttctttc
    14701 ctctttcttt ttttactttc cctcatctta ctatgctcta gcaaaataag caaaaaaggg
    14761 gagaatagcc tcttgcaacg actgatcatc gcttgatctg ttcctttttt actgggcaag
    14821 ctgtttgaca gtcatcacaa ttcttaccgg attttaaacg agtatagaca attgcgcctg
    14881 cacttccaaa gattaacaca cttaataaga atgtcgccat cctattcctc tccttctaat
    14941 gacaatatag tataaaactg gttcttggat tttggctgac ggaacaaaac ataaacgagt
    15001 cctatcatca gtaaaatagc aagatacgtc cctaacgcta cctgtccacc ctccaataag
    15061 tgtcccaact gataaatcac aaaactaact aaataagcta aaccgcattg atagcctatg
    15121 gcgatccaag tccatttctt ggcattcatt tcccgatgga tagccccaat tgccgcaaaa
    15181 caaggcgcac aaagtaaatt gaaggctaac aatgaataag ctgctgcggg agtatatgtg
    15241 tgttgtagca cttgccagat ttctctgcca ttttcggata cttccgcatg accaaacaaa
    15301 ataccaaatg tgccaataat attttcttta gcgaccaatc ctgtaatcgc tgcgactgtt
    15361 ccttgccagt ttccccaacc aagcggctga aaaacaactg ccaggattcg cccgaaaaag
    15421 gctaagatac tttggtcttc agaaacaggt tgagcataaa aattataaga agagctgaac
    15481 cagatcacga tactagaaac aaagataatc gttcctgctt ttttaacaaa agacttgctg
    15541 cggtcatagg tttgtcttag gaccgctgac cattgaggaa aatgatatgc gggcaattcc
    15601 atgataaaag gagctgtatc tccagcaaac aaacgtgttt ttttcaagct gattccagag
    15661 aaaataattg cagtcatacc aagaaaatag gcagaaggag ctacccaaga ttgatgagga
    15721 aaaaaggccc ctgctactaa ggcaataatc ggcaactttg cagaacaagg catgaaggtt
    15781 gtgaccatga tcgtcaaacg acgatcttgc tcgttttcaa tcgtgcgact ggccatgacg
    15841 cctggcactc cacatcctgt agcaatcagc ataggaatga aggattttcc tgaaagaccg
    15901 aatttcctga aaagtcgatc catgacaaaa gcgatcctcg ccatatatcc gcagtcttcc
    15961 agaaagctca agcataaaaa caatataatc aattgcggta gaaatcctaa cactgctccc
    16021 acgcctgcga tgatgccgtt caagatcagc tcctgcatcc atcccgctac ttgccattca
    16081 gctaacaatc tgccaacatg ttctggtaac catgtaccaa acaatgtgtc attgatccaa
    16141 tctgtcccca ttgttcctac tgtttgaata gccagataat agatcagcca catcacaaat
    16201 gcgaagatcg gcaaggctaa ccaacgattc gttgcaatct gatcgatttt gtcactcatc
    16261 gataattgga aagaatcatt tgacacaaca cagagtgtac atagttgggt aataaattca
    16321 taacgttcat tgaccagaat cgtctcacta tcgtcgtcca atagtttctc tgttaactgg
    16381 atcagttgct cgatctcttt ttgctgagaa actgctatct cgtaatcctc tcttaccttc
    16441 tgatctcgtt caaaatattt cattgcatac cagcgtttct tgccgctttg ttctcctagt
    16501 acatcttcaa tttcatgtaa agctgcttct aaacgtggat catatgtaca gggaacagga
    16561 atagaaggcc gcttttttgc agactcctga atcttttcga ttagtttttc gattccttgc
    16621 tttttcaata cgctgattgg taaaactggt acaccaagac cataggaaag cttttctaga
    16681 ttgatttttt ttccttcttt tttgatgaca tccatcatat tcagaccaat gatcatagga
    16741 atgtctaaat ccaataactg cgtagttaaa taaagatttc gttctaaatt ggtagcatca
    16801 ataatgttga tgatcagttc aggctgttcc tgaaccaaat aatctcttgc aatcacttct
    16861 tctggtgtat aaggagacaa agaatagatg ccgggtaggt cctgaatatg aatgttcgga
    16921 ttttttttca acgatccttc ttttttttct actgttacgc ccggccaatt ccctacatat
    16981 tgattcgaac cagtcaagag attgaacaag ctagttttcc cgctgtttgg atttccgact
    17041 aacgcgatat tcattctttt tcctcccttt gtatcaagat tagttcggcc tctgactttc
    17101 gtaacgtcag ttcataccct cgcactgtca gttcgattgg atctcccaga ggggctagtt
    17161 ttcggataac tatttttaca tttcgcgtca atcccatatc cattaaccgt cgcttcactg
    17221 cgccttgtcc gtggattgct acgacgatcc cagtctctcc tgcttttaat tgatcaagag
    17281 aagtccagct ttcagaggaa gcagtctttt tattgacaaa gatttgacct agtatttccc
    17341 gacttactgc cactcgatga ctttttacca gtaaaatggc attgttgcct gataaattga
    17401 cgacgacgat tttacttccg gcaacgatcc cgatattttg caaatggcgt tttgtttttt
    17461 cttctgtttc gattcgttcg acttgataaa cgaaattctg ctttgcctgc gctaaggtct
    17521 gcatattgat tcctctcttg tgaaataaat catgtattaa aatcattcat tatatgttct
    17581 aattttctta cgtgttacgc aaataaatga gaatcattct cacatagaat actctcggta
    17641 attgagaatg tcaattatac ttgtgatatt atgagcgaat ctttagtatt gatagataaa
    17701 aatgagaaaa aaatatttct tcatagtttt ccacaatttt ttctctatta aatttgctat
    17761 tttcccacac gatacttgtt ttcagctctt ttttcaaaaa cacaaaactt agtattccac
    17821 agtttccaca acacaatatg tagtgtttgt tgtttgactt ttttactaag agttttatac
    17881 tatctattat agataataag aatgtgttag aggaggcact caccatgaac gtaaaaatct
    17941 tttctaaaaa taattgtatg caatgtaaga tggtcaaacg gtttttaaca gaaaatcaaa
    18001 ttgcttttga agaagtcaat atcgatgaac agcctgaagc agtagactgg ttgaaagcac
    18061 aaggattcca aagtgttcct gtcattactt ctgatgcaga aacagttatc ggattccgtc
    18121 ctgatcagtt gcgtaaactt gccagctaac atgactaaaa gaatcaaaac gtgatacatg
    18181 gatttgaagg gcttgagaca gcaccagttt ttgtcgcaaa cttccaaatc cttttttaaa
    18241 gcttaaaaac aatgcaatga tttgcaatca agcatcatca aatacgaaat gaaggttggg
    18301 cgtacgtatg agtcttaaaa atttacaaga tgtcagttat ttcaagctga ataatgaaat
    18361 caatcggcca gtcaatggtc aaatcccttt gaataaggat aaagaagctt tagttgcctt
    18421 ttttgaggaa aatgtcaaac caaatacgat gacttttcta tctattatgg aaaaaatcaa
    18481 ttacttgatc gatcaagaat atatagaagc agaattcatt caattgtatt caccatcatt
    18541 tattgaaaag ctatatcaat ttttggacga gcaacatttt tctttcaaat cttttatggc
    18601 tgcttacaaa ttttattctc aatatgcgtt gaaaaccaac gacggttccg cttatctgga
    18661 aacttatgaa gatcgagtag ccttcaatgc gctttacttt gcgaacgggg atgaagaatt
    18721 agcacttgct cttgcagacg aaatgatcca tcaacgatat cagccagcta caccttcttt
    18781 cttgaatgct ggacgtaaac gtcggggcga attggtgtct tgtttcttga ctcaagtcac
    18841 tgacgatatg aactctatcg ggcgctcaat caactctgct ttgcaattgt cccgtattgg
    18901 tggcggcgta gggattactt tatcaaatct tcgtgaagcc ggcgctccta tcaaaggata
    18961 tgagggtgct gcaagtggtg tcgttccagt catgaaatta ttcgaagata gtttcagcta
    19021 ttctaatcaa ttaggtcagc gtcaaggagc tggcgtggtt tatttgaacg ttttccatcc
    19081 agacattatt gctttccttt cagcaaaaaa agaaaatgca gatgaaaaga ttcgcgtaaa
    19141 aactctttct cttggcgtga tcgtacctga taaattttat gaattgacac gtaaaaacga
    19201 agatatgtat ttatttagtc catatagtgt cgaaaaagaa tatggtgtcc cattctctta
    19261 tgtaaatatt acagctgagt atgatcatct agttgcaaat ccaaacattc gcaaacaaaa
    19321 aatcaaagcg cgtgatcttg aaaatgaaat ctcaaaatta caacaagaat ctggctatcc
    19381 ttacgtaatc aatattgata cagcgaaccg cgagaatcca atcgatggca agatcatcat
    19441 gagtaattta tgttcagaga ttttacaagt tcaaacgcct tctgtgatta acggcaaaca
    19501 ggaatatgaa gtattaggaa cggatatctc atgtaactta ggctcgacaa atatcgtgaa
    19561 tttgatgcaa agccctaact ttggtcaatc tgtgcgtacg atgactcgtg cattgacatt
    19621 tattacagat gcatctgata tcgatgtcgt accaccgatc caaaacggaa ataagctgaa
    19681 tcatacgatt ggattaggtg ccatgggctt acacacttat cttgcaaaag aacaaatgga
    19741 atatggctca gaggattcat tagactttac aaatatttac ttcatgctgt tgaattattg
    19801 gacacttgtt gaaagcaaca atatcgctcg tgaaagaaaa caagttttcc ataattttga
    19861 aaaatcagct tatgctgacg gcacttattt cgaaaaatac gtaactggag aattccagcc
    19921 aaaatcagaa aaagtcaaag cattgtttga aggcattttt atcccaactg ctgaagattg
    19981 gaatgctttg aaacaagcag taatgaaaga tggactgtat catcaaaatc gcttggcagt
    20041 agcaccaaat ggctcaattt catatatcaa cgatacgagt gcaagtattc atcctatcac
    20101 tcgcatgatc gaagaacgcc aagagaagaa aatcggtaaa atttattacc cagcgcctta
    20161 tctatccaat gagacgattc cgtattacac ttctgcttat gatatggaca tgcgtaaagt
    20221 aatcgatgtt tatgcaatgg cacaacaaca cgtcgatcaa ggcatgagtt tgactttatt
    20281 catgcgttct gaaatcccag aaggcattta tgaatggaag acaacaacga agcaaacgac
    20341 acgtgatttg aatattttaa gacattacgc tttccacaaa ggaatcaaat ccatttatta
    20401 cgtacgtacc tttactgatg atgcagaaga aatcggaagc aatcaatgtg aaagctgcgt
    20461 gatctaatat catagataga ttcgcttatt catattttaa ttaaaggagc attctcatgt
    20521 cagaaacata ttatgaagca ataaactgga atgaaattga agatatcatt gataaatcca
    20581 cttgggagaa gctgacagag caattttggc tagatacacg tatcccactt tcaaatgacc
    20641 tagatgattg gcgtacattg tctcaattgg aaaaagatac agtaggacat gtatttggcg
    20701 gtttgacact gctagatact gtccaatctg aaagtggcat ggatcagttg cgtaaagatg
    20761 tccgcactcc ccatgaagaa gccgttttga acaatattca attcatggaa tccgttcatg
    20821 ccaaaagtta ttcttctatt tttagtacac tgaatacgaa aaaagaaatc gaagaaattt
    20881 ttgactggac aaatacgaat ccttatctgc aaaaaaaagc tgagcgtatc aatgaaatct
    20941 acaaacacgg tacaccgcta gaaaagaaaa ttgccagcgt ctttttagaa acattcttgt
    21001 tctattcagg tttttatact cctctttatt atttaggaaa caacaaattg gctaacgtag
    21061 cagagatcat caaactaatc atccgagatg aatctgtaca tggaacctac atcggttaca
    21121 aattccaatt aggattcaac gagttacctg aagcagaaca agaaacgtta aaagactgga
    21181 tgtacaatct tctttatgag ctttacgaaa acgaagaacg ttatacagaa gaattatacg
    21241 atccaatcgg ctggacagaa gaagtcaaga cattcctacg ctataatgcc aacaaagcat
    21301 tgatgaacct agggatggat ccactctttc cagatactgc caatgatgtc aacccaatcg
    21361 taatgaacgg gatttcaaca ggcacaagca accatgactt cttctcacaa gtcggaaacg
    21421 gctatttgtt aggtcatgta gaagcgatga aagacgacga ttatttgatt ggattggaat
    21481 aaggatttat tttaattcaa aaatttttcg aaaaataaaa agagtttagc gtacagatat
    21541 tttaaatgta cactgaactc ttttttatgc ttattcactt gtttcttcca gcacttttgg
    21601 actgtctaac ttttccgaaa catgttccat tcttctcaat aaatagattt tccggatatt
    21661 taatattatc gtcttaatca ctgcatagac aggtatgcaa atcagcatgc ctaatattcc
    21721 tgcgacactt cctgctccaa tcaataccaa gatgatcgtc aaaggatgga tattcattga
    21781 tttcccaaat aacaacggct tgatcaaatt tccatctaat tgttggatca ctaaaatcga
    21841 caacgccata tacaaagctt gaaatggaga gataaacaaa ccgacaatga ttgctggtac
    21901 cgctccaata aaagggccga catacgggat aatattcgtg attccgcaaa tgaccgcaag
    21961 caacaagcta taaggctgat cgaatattct cattgccaaa aagctcatta caccaataat
    22021 caaagcatct aagatcgtac tgctgatata ggcagataat gtttcgttta attcttttac
    22081 cgtttggcgt aactctttac gaatcgcttt cggaaagaag tgagacaacg catcaataaa
    22141 tttgtgccca tccttgaaca taaatagcaa aataaatgga acggtaaata acaaaataaa
    22201 aaattgcatc ataaatgaaa tgatttttga gacacttgca gataaactga ctaatatgat
    22261 attgaacaaa ttactaagag ataaatttgc tgatgctaat tgttcttcca aattgaaatt
    22321 tttaaactct tcccgctgcg ccaattcatt taaccatttg cttgtttcat ctgcatacat
    22381 tggcaagctc tgggtcaatt gaattgtctg ttccattaac tgaggcacta cattcatgac
    22441 agttaaaaca actaaaatga ttacgaccaa aaacgtcaat aaaaaaccga acactctcgg
    22501 gatccgatgc ttttcgagaa aaacaacgat tggatcgaac atataataga taaaaccagc
    22561 aacaagcaat ggtaaaaaaa ctgccgaaag cattttcaat attggactaa aaatattcgg
    22621 catttgtaaa ataaagtaca cgccgatgat cgtgagtact agctccactg tccagaaaaa
    22681 taattttgat tgtttaaaac gtgattgcat acatctcctc caaggtcctt tgatacttct
    22741 attctatcat ttaacaaaga gttacgcgct gagattttca tttgcttaaa aaaaacaaaa
    22801 aaaataaaca tattttaatg agtagacgag tacttaaaca aaaacacggt ttggagtagt
    22861 gacaaaaatt atactgcagt ccctttttcc aaataaacgg tgttcaaaag cttgcatctt
    22921 cgtaataagc ccagccaaac gaaaaatata aggaactatt tttatttggc tgggcttatt
    22981 acttgatgta ggacatctat tttacaacct cagatcattt attgcgcaat actgactaaa
    23041 tgcaactttg tgatattttt gtgtacggac aactcctcga tcacatcggc ataagtgagc
    23101 ccttttggaa gatcaatcgt atagatattt ttgtacactc ggtagtcatc aacgaatttt
    23161 acgtcaaaat tcacatcttc gattacgata tttttctctt caaaataatc ggtaagaaaa
    23221 tctttggttt cttttctatg gataaattgg atttctaact ttttagtcgt aggtacatgg
    23281 atcacgcgtt tcactactgt gagtgcaata gcaatcccga taaaactgat gatcgcaatg
    23341 gaatagtaac ccatgccgat ggcgatccct aatccagcaa ttgcccataa agaagcggca
    23401 gtcgtaagtc ccgtcaccga ttgtttcgtg acgatgatcg ttcccgcgcc taagaaaccg
    23461 acaccactca ccacttgagc aatcagcctt gcttcatctg aacgaatcgt tccagcaagc
    23521 tgtggatact ctaaagcatc tcttaatgca ccactagcga tctcaacttg gatcaatgca
    23581 atgatacatg ctcccataca aactaaaata tgcgtacgca tacctgctgg acgattttta
    23641 tattgtcgtt caaaaccgat tgctccgcca aatagcatag cgatccctaa acgtaaaata
    23701 atctctggaa ttgtcaatac catatcattc atctaaacac cctccagtcc aatatatcat
    23761 gtctgaaagg agcagacaaa aaaagtgcaa tttttacctc ttacgaaaaa aggactgtga
    23821 caaaattttt gtcatagtcc tttttatgaa taaacggtgt tcaatcagct gaccctcggt
    23881 attactcaac aaacggcaaa atatggggag ctatttttcc tttgtcttct ctaatactca
    23941 ggtcaaaacg ctgatttcac aacctcttta gcctactatt gaaaattaca acttacttgc
    24001 tgcttcttca tcgatgatca caacaacatt gtcgtgattt tgcaatacac ttgctggcaa
    24061 atgattcgtt acaggtcctt caatcatccc tttgattgca tcagctttgc tttcgccaaa
    24121 tgccatcaag acgatttctt tacttttcat aattgaaccg attcccattg aaacagcttt
    24181 tgttggtaca tcttctgctt tatcgaagaa tcgtttgttt gcattgattg ttgattctgt
    24241 taagtcaact actgaagtcg ttccgtcaaa tgaagcacca ggttcattga aaccgatatg
    24301 tccattttgc ccgattccta agatttggat atcgattgga tgtgcatcga tgatttgatc
    24361 atactttttg catgctgctt ccagatcttc tgcttttcca tctggtacaa acgtttcttt
    24421 gaatggtttt ttatcaaata attggacatc catgaaatga cggtagcttt gttcatctga
    24481 accgcctagt ccaacgtact catctaagtt tacagaagtc atttcactga aatccaaatc
    24541 gcttgaagtc atttctttat ataaagtaac tggtgtgctt cctgttgcca atcctaatac
    24601 ttttgcacct ttgttcatac cttctttgat gatttcaaat gctttttttc cgccttcttc
    24661 agcgtttttt acacgaatga tttccatagt gattgctcct ttatattttg gtatagccca
    24721 attatagcat tctttttttc tttttacaat aattagtata gaccaaattg catttttttc
    24781 attttcttga caataaatag gaatccgtgt taggtttcat aagatggttc aatcaaacaa
    24841 tccatgttgc atgaaaacca agcaagtgat tcactgtgga cgctttatgt ctgcagtttt
    24901 tttatgaaaa aggagttatt atgagtatac tgacattaaa caacattacc cagcaatttg
    24961 gcgacaaaat cctctatgaa ggtgtcgatc tgcaattaaa tgctggcgaa catcttgggc
    25021 tgattggaca aaacggagcc ggtaaaagta cattgattaa aatcatcact ggtgagatct
    25081 taccagatga cggacagatc cattggcaaa aaaatattca caaaggttac ctcgatcaat
    25141 atgtggaagt cgatgaaaca ttaacaatcg aagaatttct aaaaactgcg tacgcaaaag
    25201 aatacgaaaa ggaagaaaaa attgcttttc tttaccaaac atatagcgag accttcgatg
    25261 attccttgct ggaaaaagct gggaaactcc aaacggaatt agaccaagga gtgttttatc
    25321 aaatcgacac cttagttgct gagatgagca gcgggttggg gatcgatgtc ttaggtttag
    25381 attcactgtt gaaaaatcta agtggtggac aacgttcaaa ggtgatttta gcaaaactac
    25441 ttttagaaaa cccagatgtt ctgatcttag atgaaccaac caatcactta gatgatcagc
    25501 atatccaatg gctgacgcag tttcttcagg attttgacgg tgcgtatatc gtgatttccc
    25561 atgaccaaga atttcttgat cagatcacca cccatatcgc agacatcgag tttggaaaga
    25621 ttactaagta tactggccat ctaaaacaag cattgaaaca aaaggaacaa aatcgcgaaa
    25681 gctatttgcg ccaatatcat gctcaacaaa aacaaatcga aaagaccgaa gcttatattc
    25741 gaaaatacaa agccggttcc cgatcaacga tggcaaaaag ccgacaaaaa caattagata
    25801 aaatcgaacg gctgacgcct ccagcttcag caagtaaagc tgtctttgat tttccattct
    25861 cgcctattgt cacgacatta gcagtggaaa caactgattt agtcatcgga tatgatcgac
    25921 cgctacttgc acccatcaat ttgaccatcc gctttggtga aaatattgcc attcgaggct
    25981 tcaacgggat tggaaaatct actttattaa aaacactgat cggtgagatt gaaaaaataa
    26041 gtggcgattt ccacttccca gataacacaa aaatcaatta cttttcacaa gatctgtact
    26101 gggaaaatcc attagaaaca ccactacaat atttaagcag tcaatttcca aaagcgacta
    26161 tcaaagaatt acgtcgccaa ctagctaaag cagggttagt taatcaatta gcaagtgaac
    26221 ctctcactac attaagtggt ggggaacaaa ctaaggtgaa acttgcacag ttgacaatga
    26281 accaaggtaa tttactgatt ctcgatgaac cgacgaacca tatcgatcaa gaaacgaaag
    26341 aaagcttaca agacgggata cagaaatttc caggaacagt aatcatcgtc tctcatgaac
    26401 aagaatttta tcaagatctt gtgcaacgag tcattgagat tgaaccaaaa taaacgtttg
    26461 attgaatagt tgaaaaaaag gagctgtgac aaaagttttg tcacaactcc ttcttctgaa
    26521 taaatggtgg ccaattagct gaccttcggt attagctcaa aaaacggcaa aatatgagga
    26581 gctattttta tttggctatt cttattactt gatgcagaac agcttttcac aacctctttt
    26641 cgtctatttt ttattttcga gatttctctt tcctttaaaa acaactgttt gaaagaagaa
    26701 cgcacatcct tgaaaaacaa gcccgctaac cgttacacct aaccagccat actgctgcca
    26761 cattgtcgtc cctagcaatg aaccagccgc acctccaata aagtacataa acataaatac
    26821 agtattattt cggttgcttg ctgcttcacc tagcccttgt actcgtgttt gattggcgac
    26881 ttgaccaaat tgattcccga cgtctaataa aataatagct aaaagcaaaa tggccaaatg
    26941 gcttccgcca accaataaag caataaagct tattgtttgc ataacaagtc ccatatacac
    27001 gatttttctt tcagaataag aatctgccag tcgtcccacg ataggtgcag caactgctcc
    27061 agacaaacca aaaatcgcta atatccctgc ttcgaatgtt ccccaattgt aggcgggact
    27121 gctgatataa aaaatcaacg tagaccaaaa gatcgaaaat gttccaaaca tgaaaaatcc
    27181 actgactgcc gcttctctta atagacgttg agaagcaact aaatgcggca aacttttaag
    27241 tgaatcaagg tatgaaacag ctgtactact ttgctggaca gaacgcggca ttttccagta
    27301 aagcagaagt gtaagaattc cgactgcaca taaagcaaat aaatagatca tccgccaaga
    27361 aaaaagactg gcaacaatac cagataccgt ccgagaaagc aaaatcccca cgagtaaacc
    27421 gctaagcaat gtacccatga ccttccctct tgcttttggt cccgctagta ccgcaccgta
    27481 aggaatgatg atttgcggca cgatcgaaag taatcctatt aaaaaagaag cgcatgcaaa
    27541 taacgtaaac gaaggcgcaa aaaaagcggc caacagagag acggcagata acgctgccat
    27601 tcgaatgatc aattttggac gatccaccac gtcccctaaa ggaactaaaa acagtaaccc
    27661 taacgcatag cctaattggg tcaacatcgt caatatcccg actgcacttg tgctaacaga
    27721 taaactagct gctacttttg ttccaatcgg ctggatgtaa tacatattgg caacaacaac
    27781 gccacaagtg attgataata gtaaaataag cgaagttgtt aaaggttttt tttcattact
    27841 cttcattgat ttcccccatt tcctatctta gtttacaact tatggaaaag attggaaata
    27901 gaaaaataca actattcgcc acacttatta tttgtgcttt tgttttcctt gttttttctt
    27961 gcgatcttta taaatgaaga caactaaccc tactagcaca gtaacacttg caaccaacgt
    28021 gactgcagtt ttgttatatc cgtgaaacag agcttctcca ccacacgcat acaacacaga
    28081 cgaagggatg actccaatca cgatcgacaa tatgatttgc tgtagaggca atttcatcgc
    28141 atctgcagca aaattgacca tagaagatgg aataaccggt atcatatagc ctaacattac
    28201 acctattttt ggatgtttca tttgtcggat tgcttgcacc caatgattcg tttcggtttt
    28261 cttatctaaa aattttaagc gatgcataag gaaaattgca gtgatgttac caagagcatt
    28321 acccaaaatg ttgatgatcg cacctgtcag tggtccaaag ctcaaaccag caatgactcc
    28381 aactactgaa gtaggaatac ctggaacagc acacatcacc gctgtcaata cgatcaagag
    28441 tatcgatgca aaagtcccat gcgaacgaat atgtgcgagt agctctgcct tactcgctct
    28501 cggatttaaa aataattgga tgtctgtctg atattctaaa tacaaccgat agcccactac
    28561 cagtatcaga atgattccca acgagatcaa tatcaatcgg attattttct ttttcatatt
    28621 tcctcctgaa aaaaatctat attcattaaa taatagttta acataaaaac aaaaaagcac
    28681 cgaaatccaa cataggatct cagtgctttt aaatagtaaa aattatttaa cagttacaga
    28741 tgcgccaact tcttcaagtt tagctttcaa ttcttcagct tcttctttag atacgccttc
    28801 tttaactggt gcaggagcgc catcaactac agctttagct tctttcaagc ctaaaccagt
    28861 tgcttcacga actgctttga taactttaac tttttggtct ccagctgcag ttaattctac
    28921 agtgaattct gtttgttctt cagcagcagc agcgccacca gcagcagcta cagctacagg
    28981 agcagcagca gatacgccaa attcttcttc aatagcttta actaggtcgt taagttctag
    29041 gatagttgct tcttttaact cagcaacgat gttttcaatg ttcaatgcca ttataatttc
    29101 ctccgtttaa ttgttctttt ttatttaatg ctttatgcgg caattaagct gcatctccat
    29161 cttctttgtc tgccactgct ttgacagcgt aagccacgtt gcggactggc gcttgtagta
    29221 cagatagcaa catagataga agtccttcgc gatttggcaa ttttgccaat gctgtgattt
    29281 cttccaatga agagacttta ccttcgatga taccgccttt gatttctaat gcttttgctt
    29341 ctttagcaaa ttcgtccatg attttcgctg gtgcgactac atcttcgtta ctgaatgcaa
    29401 cagctgtagg tccagtgaat acttcgtcca tgccttcaag gccagctttt ttagctgcac
    29461 gtgaaagaat agaatttttg ataactttca tttctacgtt agcatcacga agttgtttac
    29521 gtaaacgtgt tacttcatca actgttaatc cgcggtagtc aacgactact actgatgcag
    29581 ctgctgtaaa tttttcgctt acttcatcaa cgattgctgc tttttttgcg ataattgctt
    29641 cactcatttt tgagtttcac ctcctgaatt ttgatggaag agttttttgc actgaaaagg
    29701 caagtcactt ttatagttac tttgctcaac cagtattatt catcacctat tcacttcgtt
    29761 catagtgatt ctactcgctt tgctcgaaag gaaactcctt tcgctttgct caaccagtat
    29821 tgttcatcat ctcttcactt cgttcatagt gattcacaat aaaaaactct atgccaccgc
    29881 agacatagag ggactattga atatattcaa taaacgtcct cggtaggaaa ttaaggcttg
    29941 atgccaccta ctgtcttcgg tacaagttaa ttattaacct caactagctt agcatgctaa
    30001 actagttgag tcaagaatta tttttcagtt ggatcaatca acattctaat atttaattag
    30061 aaagaagctt ggtcaacatg gataccaggt ccaaatgttg ttgtgatcgt tacatttttc
    30121 atgtattgac ctttagctgc tgatggttta gcttttagca atacatcatg gattgctgca
    30181 aagttttcaa ctaatttttc atcgtcaaat gaaacttttc cgattggtac atggatattt
    30241 ccagctttgt ccacacggta agttacttta ccagctttca cttcgtttac tgcttttgtt
    30301 acgtccattg taactgtacc agttttaggg tttggcatta agccttttgg tcctaatact
    30361 cgtcctagac gacctacagt agccatcata tcaggtgttg caacaactac atcaaagtca
    30421 aaccatccgt tttggatttt ttgaaccatg tcgtcgtcac ctacgaaatc tgcaccagct
    30481 gcttcagctt cttttgcttt gtctccttta gcaaaaacta aaacagtttg tgttttacca
    30541 gttccgtttg gtaatacaac agcaccacgg atttgttggt ctgctttttt agggtctacg
    30601 ttcaaacggt atgcaacttc aactgttgca tcaaattttg caatgtttgt ttcttttgct
    30661 aaagctactg cttcggcaac aggataaact ttacttgaat caactttttt taatgcatct
    30721 tgcatttttt tgctcttttt agccattttg gttcctcctt gattgtggtt ataacggttg
    30781 tacctcccac gtgttctata tctttcaata tagagccaac tgagaagctg ctgtcttagg
    30841 gtgtatagat tattctacag tgatccccat gcttcgtgca gttccttcaa ccatgcgcat
    30901 tgctgcttca acgttagctg cgtttaggtc ttccattttt aattcagcga tttctcttac
    30961 ttgatcgcta gaaactttcg caactttatt tttgtttggt tcgcctgaac ctttttcgat
    31021 tttagctgct tttttcaata gaacagcagc tggcggtgtt tttgtaacga atgtgaatga
    31081 acggtcttcg tatacagaaa taacaaccgg aatgatcaaa cctgcttgat cagctgtacg
    31141 agcgttgaat tcttttgtga atcccatgat attgataccc gcttgaccta gtgcaggacc
    31201 tactggtgga gctggagttg ctttacctgc aggaatttgc aatttaacga ttttttctac
    31261 tttctttgcc acgagacata cctccttaag tccgtgatgt ggttaattgg agatgcatat
    31321 ttctcctccc acgttttatc tgatctgaaa aaatccagac aaataatgtg caaaacaatg
    31381 cacactggta cagtatagca aatttatttg ttttttcaag atttttttct gctattttta
    31441 cattttgctt gaataaacgc taaatttatt ctaaaaaaac aacaattttt cgttctcatt
    31501 tcttctttta tgttacactt gcgctagcat ggttcaacag atgaaagcaa acaataacac
    31561 ggttttttag acccttgtac aaagattcct acataacaaa atgaggtgga gaaaatgaaa
    31621 gatttaaggt atagaagtgt ctttgatatt attggacctg tgatgattgg tccaagtagc
    31681 tctcacactg ccggagctgc tagaatcggg aaaatcatac gtagtatatt tggcgaacag
    31741 cctgattctg tagatattta tctatatgaa tcatttgcaa aaacctatcg ggggcacgga
    31801 acagatattg cattagttgg cggcctgtta gggatggaac ccgatgatga acgtttagct
    31861 gattctttga aattggcata tgaagccggt atggaagtct tgtttgttcc taagagtgaa
    31921 aaagccgaac atccaaactc tgtaaagatg cttctaaaaa aaggaacacg aaagctttca
    31981 gtcactggca tttcgatcgg cggtggcaat atccagattt ctgaattgaa tggattcaaa
    32041 atttctttaa gcatgggtac tcctaccttg atcgttgtcc accaagatgt tccaggtatg
    32101 attgctaaag tgactagtat actttctgag accaatacga atatcggcac tatgacagtg
    32161 acacgggaat caaaaggtga aaatgccatt atgataattg aagtagatga tcctcaagta
    32221 gaagaaacgg taaaaagact caaacagctg ccaaatatcg acagcgtaaa ttatttcgat
    32281 taaggagcta aaaaaatgtt tttatcgatt gaagaattag tagatcaagc aaaagcttat
    32341 ccaagtgtag cagaattgat gattgcagtt gaaatggaaa tgagtggccg ttcccgtagt
    32401 cacatcatcg agatcatgga aaaaaacctc tcagtaatgg aacaatcaat caacgaggga
    32461 aaagaaggtg ttacctccgt cacaggaatt accggtggtg atgcaaaaaa attagatgat
    32521 tatttaaatg aggcagactt tttaagtgga gaaacaatct taaaagctgt acgcaatgct
    32581 gtagctgtta atgaagtcaa tgcaaaaatg gggttgattt gtgctacacc gactgccgga
    32641 agcgcgggtg ttgttcctgg tgtgctgatg gctgtccgag atcggcttga tttgacacat
    32701 gaacagcaat tggaattctt atttaccgct ggcgctttcg ggttagtcat cgcaaacaac
    32761 gcttctatca gtggtgcaga agggggatgt caagcagaag ttggttctgc aagtgcaatg
    32821 gcagcagcag ctttggtttg tgcaaaaaat gggactcctc atcaagcagc acaagcagta
    32881 gccattacat tgaaaaatat gatgggactg atttgcgatc ccgttgcagg cttagttgaa
    32941 gtcccgtgtg tcaaacgtaa tgctttaggc tcttctcaag cttttatctc tgctgatatg
    33001 gcattagcgg gtatcgaaag tgtcattccg ccggatgaag tcgttgctgc aatgtaccaa
    33061 gtcggacgtc aaatgccgtc gattttcaaa gaaacagcag aaggtggctt agctgttacg
    33121 ccaactgcta aacgacttgc ggaagagatt ttaaataaga gggcgtgata aagctcctta
    33181 atttcgagta ttaagagatt agttatcttc ataacaaaaa acgaagagag gactaattgc
    33241 ccttctcttc gttttttatt aatccatcaa tttcgtattt tttacttcat cgatcgtttt
    33301 tgttcctgca agttgcatcg tgatcgacaa ttctttgttc aggtgttcaa aaacagatgt
    33361 tactccttct gccccaccta gattcaaccc ataaatcact ggtcggccaa tcgcaactaa
    33421 gtcagcacca cttgccagag ctttgaagac atgctctcct cgacggacac cagagtcgaa
    33481 aatcactggt acacgtttgt tgactacttc ggcaattttt ggcaatactt caaaggacgc
    33541 aggacctcca tctagttgac gtccaccatg attggatacc cagataccat ctgcccctgc
    33601 agagatagcg attactgcat cttctggcga ttgtattcct tttacgataa ctggaagatg
    33661 ggtgatttct ttgattgttt tgatgtcatc tggtgtcaag ccttgttttg cagctgcata
    33721 aatttctgcg attccttttc cttcgccatt accacttgca ctttgttcgc tatacgcagc
    33781 taagttaggc attggtaatg gaaattggaa ttgattgatg acgtcttctt cacggtaacc
    33841 accgagcgtt gaatctgccg ttaaaatgat agctttagcc cctgcttcta ctgctttgtt
    33901 caaaatgaac tcattgaatc tgtcgtcttt actcatatat aattggaaaa actgcggtgc
    33961 gcctggcgct gcatcggctg cgtctttgat tgtcgtattt gcataagtgc tgatggaaaa
    34021 gattgatcca gcagcagcta ctcctttagc tgtatcagct tccccttttt catgtgccaa
    34081 tccttgggcc gctgatggcg cttggataat cggtgtatct aattcaattc cgaaaacaga
    34141 tgtatgcaaa tcggctgagt cgattccgcg taatatccgt ggcatgattt tctttgtatt
    34201 aaaagaagtc gtattttctt tcatcgtcca ctcatcttca gaaccaccgc gaatatagcc
    34261 aaaagctcct gcttccatgc gctcttttac acgaccttct agttaggcaa tgtttacaat
    34321 atcgattgga tgttcttcat tacttgtatg ataagtcata gtagatcctt ctttcatctt
    34381 cttgattaca tataaatcat actaaactta caaaaagtaa gcaaacattt actctcagat
    34441 acttttatcg ctattctttc caaataaatc gacttacaag ctgatctact tcttggtttt
    34501 catgaagcat actatgagag gcattttcac ctgtcactac tttttcctct atttcatttc
    34561 cgcgttgctt caacaacgca tagaccgcta atgcactgtt taacggtact gttccatcac
    34621 tcaagtctgt ttcatctagt tgaccagcaa tcaagaaaaa tcgagtggtt ataggaatat
    34681 taccgatcat ttgctggtaa tcttgatagc ggttagaaac gacagcaggc ccctttgcta
    34741 actcatctgt cagagactgc gcactatcat cgacaaaatc attaaaaggc gcgccaattg
    34801 ctgttaatgt ctgaacttgt ggcaatgacg tatcctgtcc atacgttcct aaatagcgta
    34861 gtgcactaac tcctcccatg gaatgcccca ctatgttgac tttatctatg ccgtagtttt
    34921 ctttcagata caaaagacaa gttttgatcc attctgcttg attccactcg ttatttttat
    34981 tatcttcaaa caatacttgg accatcggat tgtctgcttt tccagacaaa tctcctgttg
    35041 cttgtatttg tccatctgtt cctactgtta aaaccaattc ttttactgct tgctgatttt
    35101 tttccaaacg ccgcaacatc cctttaaagg aattttctgt cccgctgtag ccgtggaaaa
    35161 aaagtgttgg aatagtggtt ttttctatca ctttactgga ttctgccgtt ttttctttat
    35221 cagaaacttc agtagtattt atcttcgtcg tctggcaacc acttaacgca aacaaactga
    35281 taaggactaa agctgctgca gttgcacgtt tgcataaatt tttgattggt tctgtcatac
    35341 acctcttcct ttccatatag aaaaaagaaa gacttgaaag gccaatcata tgatcgacat
    35401 ttcaagtctc tttattaatc gattttatct acttgatcga aatcaagttc tgtactggtt
    35461 tcacgtccaa acatatcgat gttgactttc aatttttctt tttctccgtc aacttctgtt
    35521 acttgtcctt ctaatccagc aaatgcgcct tcgatgattt tcacgacttc gccaacttct
    35581 acttctagat cattttgtcg caggctcata ccgatagaac gcaagatatg attgacttct
    35641 tctggaagta atggtgctgg tttgcttccg gctccgtgtg aaccaacgaa tcctgtcaca
    35701 ccaggtgtgt tgcggacaac ataccatgaa gcgtctgtca tgatcatttc aacaagtacg
    35761 tatcctggga atgttttatg aacgatttct ttttctttcc catttttgac ttcagtttct
    35821 ttttcttcag gaacaacgac acggaaaata aagtcggcca ttttcatact ttgcgcacga
    35881 gattcgatat ttgcttttac tttgttttca tatcctgaat atgtatgcaa gacataccag
    35941 tttttttcaa aagattccat tgaaggctcc tcatttcatt gtaaaataaa aaaacctcag
    36001 tacacccgaa gtttttcttt cgcttcatta tagcactaaa agtacgttgt ggctagcgag
    36061 ttattttaaa atccagccaa ataagctttg gatggctgta tccattacgt aaaacatcaa
    36121 tccgaaaata atagaagttt cgatgactac taacgtatct ttacggagtt gttttctgct
    36181 tggccaagtt acttgtttga tttcatcttt tacgcttttt agaaatttca tgagacaacc
    36241 tcccttgcta ctgtttattt cgtttcttta tgtaatgtat attgattaca atatttacaa
    36301 aacttattga tttccaaacg ttcgccgctt tttccttcac tgactgattt tgtgtagttg
    36361 cgagacccac aaacggaaca agcgagtgct gcttttttct ttgccattta cttctgcccc
    36421 cttgctgaga atcagactta tacttcataa cagtatcacg taacttttta cttgtcaatt
    36481 tgtgaaataa actatctatt gttttggata aaattatgat atgattaatt tgaaattaag
    36541 ctaaaatgag acaattggag gtatagcgat gctattaaaa acacttgtat ataagaaaaa
    36601 agatctgaca accgttacag agactagtac attagaagaa gcattaaaaa ttttagaaac
    36661 ttccggatac cgttgtgtgc cgatcttaga ttcttcaggt aatattttcc gtggaaacat
    36721 ttacaaaatg catatctatc gtcataaagc aaatggcggt gatatgacgc ttcctgtcac
    36781 tcatcttttg aaaaacgcta caaagttcat ttacctggat acttctttct tcaaagtatt
    36841 ctttacgatc aaagagcttc cttatattgc tgtccttgac agtgaaaatc atttttatgg
    36901 tattttgaca catagtacgt tgcttaatat gctctctcaa tcttggagcg tagaacaagg
    36961 aagctatgta ctgacaattg cttccacagg aaagcaagga gatttggctg ctattgcaaa
    37021 aatcatttca aaacacagca gcattgccag ctgtattact cttgatatcg aaaaagacga
    37081 atacattcga cgtacattga tcacgctacc ggctaacact gaagcgaaag tatgtgaaac
    37141 gatcgtcaac cacttagaga aaaagaatta taaagtggta gaaattgaaa atttgcaaaa
    37201 ccaagaagca taatcaaaaa gcgaaaaaag aaaacagcta atctgctttc ttttttcgct
    37261 ttttataatt agacacgctt ttcaaaatca agcgcgcgat ctaaataata catcaatggt
    37321 gctgaaacag ccatgacgat aaactcactt aatgcaagcg tgccataggt tgtccaaaat
    37381 gcttggccac ctgttggaac taacatataa gcaatcagtc ccatgctgat ggtaaagaag
    37441 atcgtgttca atactaaacg catctttaca tttttcactt tgttttgcaa taaagctgtc
    37501 aggcctaaag aaagcaatgt ttggccgcca ccaaaaacca catccatgat accaaaacca
    37561 aagaaggcat tatagacgat gaccccgcct aaaactcccc aaagcaattt acggttaaag
    37621 acaactaaat gattcaaact ttctgaaata cgaaactgga tcggccctga ggatacaggc
    37681 gcaactaaaa tagttaacgc tagataaaga gccatgatga tgccatttac aacgattacg
    37741 gataaccgtt gtctgctttt cgttttttgc attttctctc ctcttttctc ctagtttttt
    37801 taacgcggga tggttgatga accgcggtta tgtgaaacaa acaataatta taacagactt
    37861 ttcatttatt tcaatccgtc ttatctgctt ttaaaaaagc aaaagcttaa acaatgtaaa
    37921 cgtttgctaa aaatcgtggg atatggtata aagtaagtgt aaggggtcat aagaattccc
    37981 agtaaagcag acgaagtagg atctgcaaga acagaattgt tgtgaaactt aaataaataa
    38041 aaaaggatgt gggaatttga gcaacctctt actagagaac ggtctagcaa gcagctgaag
    38101 atctaagtgg acatgccgaa ccttggaact tctccttacg taagtaatgg atcatgcgct
    38161 tgctaggctt ttttgtgttt ttcggtcttc ggaccttttt cattttccta gacttctgct
    38221 ataataacca agaattaatt ttgtaacaga tttttttgaa aaaacaagtt tctttcattc
    38281 aaaaaataga aaaagcttgc taattattgg ttaaccagca aacaggagta ttaaaatatc
    38341 ttgttttatt gaatagcagg aggaaatcat gaaattccat tatcatatat tgatcaatcc
    38401 atcggcaggc agcggaaatg gctataaagt agcagaaaga attttaccgg tattaaaaaa
    38461 taagcatatt gactatacac ttcattatag tgaatacaaa ggacacgatg ctgagattgc
    38521 tgaaactttg gcaaaagaaa cattgattcc ttggatagaa gaagaacaga aaacaatcga
    38581 tactttcccc cttttgatca tcgtaggagg tgacggcacc ttacatcagg tacttgatac
    38641 tttctatcag atggaagtag aattcccagt tgcttatatt ccagcaggtt ctggagatga
    38701 ttttgctcga ggggcaggcc ttccaaaaaa tcccaaaaaa ggacttcagc tgattttagc
    38761 agctcaatca ccagaaaaag tccacataat ggcttatgaa gaaaaaataa gtgaaaaaaa
    38821 aggaatagct gttaataatt tcggtatagg attagatgca gctatcgtcc atgcgacaaa
    38881 tcattcttcc acaaaaaagc gattgaacaa atacaactta ggatcatttt cgtatttatt
    38941 ctctattctc cgtgctttat tcactcaaaa aggatttcca attctggtag atgcaggagg
    39001 aaaacaatta agtttttcaa acgcattttt atgtacagca acgaagcatc ctttttttgg
    39061 cggaggaatc gcgattgttc caactgctga tgcgtctaaa ccagtcattg attttgtcgt
    39121 ggtcgaacga atcaatttct ttaaaatctt gtggctcatt cttttactta tacagaaaaa
    39181 acaattgaaa tcgaaatatt tccatcacta cacaacaaac agattacgta tcgtttcaac
    39241 aacaccgcaa catggtcaag aagatggaga agaaatggaa aaacgacctt ttgatatcac
    39301 aataaccaca actaaacagt tgttttggtg ttaataaaag aggttttgtc agaagctaca
    39361 tctggaacac cgtttattcg gaaaaaagga ctgtgacacg acttttgtca cagtcctttt
    39421 tttactatgc agttaattct ttgcccaatt gggttgccat cgatagtttc tttctttacc
    39481 caaaataaat tggatcattg aaaacaccgc agcaaaagca actaagacac aaccattgaa
    39541 ccaaaaagat tctgcaaatg tttgattgta actgagtgtt tcactgatca agttattatt
    39601 ttgaacaaac caatatgttg gtgtgaatgc cgctattttg ctaaccattt ctggcaagta
    39661 ttctgctggt acaaacaccc caccgataaa gcaactgcct gtgataaaaa tatctttgat
    39721 cccaccgctg gtttctgagt tttttaccaa tgaagtgata caagccgaaa agctaatgat
    39781 cggcaataaa aacaagaaag tatttaaaat atgataccat accgttatat cccacgaggt
    39841 gtggatcact aacagaacca ttagaagtaa gaagccactg aacaacagca gcgagtaact
    39901 aatcaaacta aaggttactt tgcgattcaa gtttcgtttg gtaatgggcg cactctggtt
    39961 tcgtttactg atctctttgc gattaaatgc tagattgatg acgctgaaac cgctaaaaat
    40021 ggatagaaac aacccataag acaagaaatt aaaggttgtg cccgtcaaca gctttttcat
    40081 ccgctgacta tatcccgcac ttagctcaac ttctccagta accgagagtg ccatttgtgt
    40141 ctgttccata gctgcatcga ttgttttatc ttcttcttga aacagaatca gtgtttgcaa
    40201 aaaggtgttc acttgctgtg taacaactgt tttagaaaag gcatctgggc gactctgtat
    40261 cttgatcgtc ggcatctttc ctacttcgac ttgttcggta aagtctgcag gcagatgtaa
    40321 gataatgttt acacgattaa aataaagagc atcatcgatt tctttttgtg aggttccatc
    40381 caatgtaacg actgtttcct tgtcattcaa atatttacga aggccatcga ctacaggcga
    40441 ctcttcttca ctaatcaagg cgattttcgc atcttgcaga gaggtatttt caacatcaat
    40501 attttgcgca aaaaagaatg tggcaacaac agtgataatt acacctatca gtaaattcga
    40561 tttatttgct ttaagcaatg tccaaatcgt tttataaagc gtcataacgc acccctcttt
    40621 ccatccaagc atttcctaac gcaaaaagga aaataaatcc gatcaaccat agaagattgg
    40681 tataaaaact agccaaatca gtgtagaaat aaagtttata caaactttcg ctgatcaagt
    40741 tgacgagatt taattgacca acaatcggaa tatgaagatc aatccaatac ttcacttgtt
    40801 ccgaccccat cataccagca aaaaagctca tcgcaatcgt cactgaaatc aagatgctat
    40861 ccttttgcac cagattcatt tttggtatca aattaccaac caatgtacct aacaaaatcg
    40921 cacacaacga ccccagagcg gtaacaatca tcaaccattg ccaacgttca ccaaagtcta
    40981 cttgatagat aaaacgaaag acagctaaca taatataaat ctctgtcaaa acaatcgtaa
    41041 agcttgctgc caaattagcg attgaaacta acgattgctt tctaggaatc aaggacaagc
    41101 gaataccatt tgacgattga tttgcttgct gatcctgtac attgcggacc ccccacatcg
    41161 tcccgtagag aatcgccatt ccaatcagag tgaagaaata aaaacttttg aaactcatat
    41221 tacgacctgc atgaacttct tgaaaagata cttcttgttc aaaaacagtc atgatgggcg
    41281 cgagatcaac gttctccact tctgccactt tactcgaaat tataccaata cgctgtaaaa
    41341 attgatccat gacgtttttc atcaacgtct gactcattcc tgcttgaccc acatggagcg
    41401 aaacagatga accatcaatg agataaaaac cagccaaatc atctgcattt agcttttcat
    41461 tcgcttctac ttccgatagt tcctgtactt caaataatgg tttatcattg acttcgactt
    41521 gttctaagac tgtggtaaaa ttttccgaaa gcgctgtttg atccgctttg attacaattc
    41581 cagtattaat cgtttcgaga ttgccacctt gatcaatctc gccaaaggcc gccataaaca
    41641 tcaatcctaa aagaattgga aaggccaatg tccaaaacaa catggattta tttcgcagca
    41701 gtatttttgt gcgatattta taaaaatgcc aaaacattat ttcccctcct ctagtctctc
    41761 aaatccttgc cagtaatctc taaaaagaca tcattcaagg acgcttcttt ggttgctatt
    41821 tttccgtaac tgatcttttc ttcttgtaag attgtaagaa tcggcaacaa tactgtattt
    41881 agttcagtag ttgttacttg gagctgacct tttttataag cgattccatc agaagctatt
    41941 gttcgctgac aacacgtttt ctgggagtaa tgggatgtcg atcgtcaaac gatccgccgt
    42001 ccgtaccata tcttttagag attctttggt tcctttagca atcacctgtc cttgatccat
    42061 gatcacgatc tggtcgcaaa gaatttctac ttcttccatg taatgtgttg tatagacaat
    42121 ggttgctcct tgtcgattca gctccttgat actttctaaa attttattcc gactttgggg
    42181 gtctacagct actgtcggct catctaaaaa aattaaccgc ggcttgtggg caatcccaca
    42241 tgcgatgttc aaccgacgtt tcaagccacc actaagttct cctggacgaa acgaaacata
    42301 tttttctaat cccactaatt gaatcacctc ttcaatcaag gctttccttt tctctttttc
    42361 ggaaacatat aaaccgcaaa aataatcgat attttcttgc acacttagtt cgtcaaagac
    42421 cgcaacgtct tgaggaacga ccccaatcat tgccttgaca gcataatttt caggagtcat
    42481 tgttgtcccg aacaatttaa tggttccttt gtcataattt aacaaagaaa gcatacagtt
    42541 gatggcagtc gatttcccac tgccgtttgg tcctaacaga cctaagactt ctccttcttg
    42601 tacttgcaga tcaaaatgat tcaatgctac aaaatctcca tagcgtttga ctaatttatc
    42661 aatttcgata atcatcatga aaaactcctt ccaaatttct tgttgatctg actataataa
    42721 agtgcaagaa aagaaactag tgacgattgg ctaaaccaca catgacattt gtcacaatga
    42781 aggagtctgc tatgcataaa tctcggctac tcaacgaaac tagctttcta ctggttatct
    42841 cattgctttt gctggtaagt caaggattcg ttgctatgca agttatctat ttattgatcg
    42901 ccgttttatt cactggtgtc agttatttac tgcctacaaa gccaaattgg attttccaag
    42961 ttattctatt tcttttatgt gcctttttac ctgatcttgt cctgtttctg ccagcgacga
    43021 tgcgagtgat cgcccctgaa gaaagccacc ttgattactt gtttttgtta ggttttttgt
    43081 tgatttcgac ggttggtaat catcccccca tcaaggtcgc ctttgtcgta attttgctgt
    43141 ttttttcctt ttacttacga aaaaaagatc aacgaacgac cgatcttgag aaaaagtaca
    43201 ttgtctccaa agatactcat tgggaaaaac aacaagagtt atcggaacaa aataaagcat
    43261 tggccctgtc acaagaaaca caattagcct tgcaaattgt ggaagaacgg aaccgaattg
    43321 cccgagacat ccatgacaat gtcggtcatc tgctgtcaag tgcgatttta caaattggtg
    43381 cgcttgaaat gatcaatcaa gaaccaaaac taaaagaacc attagaaaat ttaagtgcca
    43441 ccgttcacac tgggatggat cggattcgtc aaagtgtcca tgacctccat gagacatcga
    43501 tctcttttca acactcctta gagtttctga tcgctgattt tccttcttct gttacgattg
    43561 aaggaaactt gtttgaagga ttgaatgaaa cgcagcaaaa ctgcttctta atggtcatca
    43621 aagaagcctt aaccaacagt atcaaacata gtcatgccaa aaccgttgtt ttacattttc
    43681 gaacgttgcc ggccttttat cgcttgcaaa tcacgaatga tggcaccagc ccacaaaaaa
    43741 attctgctcc cggtattggt ttgaaaacga tgcgtcaacg tgttcaagaa caaaagggac
    43801 aagtccatat tttccaagaa aaccagcaat ttcagttaac gatcatttta ccaagggagg
    43861 gacaccaatg ataacagtag tcattattga gatgatccat ttgtgacgaa atcgttacaa
    43921 accattttag aaagcacgaa agagatccgt gtgttaggca ttggtcattg tgccaaggat
    43981 gcgctagtct tatacgaaac ccatcgtccc gatgttttgc tgacggacat ccgcatgcct
    44041 aaacaaacgg gcatcgatgc tgccaaagaa attttggcta aatttcccaa agccatcctt
    44101 ttgcttttga cgacattcaa agatgaagaa tacatccgcg aagcattttc catcggtgtc
    44161 aaagggtatt taatcaaaca gaacttgcaa gcgattattc cttctgtcaa atccgcttat
    44221 aatggacagg ccgtatttgg taatgaaatc atcgagactt tcactcaaat gatgaagaat
    44281 aaaccgacga ttgatagtca tgcttatgct tcttttagtg aacgtgagct tgcaatcatc
    44341 aaagaagtag ctgccgggaa aaacaataaa gaaattgcag atgccttgta cttgagtgac
    44401 ggcactgttc gcaattacat cagccaatta ctagaaaagc tagatttacg ggatcgcacg
    44461 caattggcta tctattttta tcagcatttg caataagtct tatctaacac aaaaaaacct
    44521 gaatgatgct ccttcgcatc attcaggttt ttttcacatc ttctattcaa ttgtcccgca
    44581 aaccatttcc tcacgattga aagaatcaag gattcgcagg gctgccagga ttcgttggat
    44641 tgttcggcgt gttaggcgga aaaataggcg ccttgtctaa cgttttttct agttttgatt
    44701 cttcacgatc gtctcgttct acatcaggac tttcattcaa tttgaattct ttttccatct
    44761 catctaactt tttaaagtca ttgccagatt cttttgctaa tttcgctaat ttatcttcgg
    44821 tttctttagc cataaagtaa cgcccccctt ttgatttcag cttagcatat cacactgaaa
    44881 aaacaaaaga aaacgctaac caacgatcat ttttagctat ttctcatctt taaaatcaag
    44941 cattttttgc cggtataaaa tcgtagggag aactgttttc cataccaatc atcggatcta
    45001 ctaactggtt atcgatcact tctgctgtaa gaacgaaatc tttagaaaca gcaggttcta
    45061 cctcttcttt cttttcttct ccaacaaatg aagaaaacag atctggttcc actgtttcca
    45121 ttacttggtt tttcgtttca ttcgtcccac tgtcatcttc tacaggtagc ttttctttta
    45181 caacccgtgg ctcttttgta tagttcccat cttcaaatgg atcatttccg accaaagaat
    45241 cttcataagc tgctagtttg gtccggagag tgatattcat tttatcatta tccatgatcc
    45301 ttgatttcaa cgtagtcatc cggcttgctg attcattcgc tacacaagtg acataggctt
    45361 gctcttcccc taacaaaatc aacagttcct tactgcgagt cactgccgtg tagagcaaat
    45421 tacgctgaag catccgctga tattgatgga ccatgggcaa aataaccatc ttgaattcac
    45481 tgccttgtga tttatggatt gagcaacaat aagaaagagt gattttattc cattcgtttc
    45541 ttttataagt gacctcattt gcatcaaact ggataactaa ttcatccact ttatcttcag
    45601 aatcttttgc caagatgata cccgtgattt ctcccatatc tccattgaat acattcaatt
    45661 cgggagtatt gactaattgg aggactttgt ctcctatccg ataaacggtg tcgttccaat
    45721 gtacttcctt ttttccaggt ttccctggat tgaatatctc ctgcatcatt ttatttaacg
    45781 catcgatccc tgcaggtccc cgatacattg gtgctaatac ttggatatct tgtgcacgga
    45841 atcccttatt tttcgctttt tccacaattt tagagatcaa gggttcaatt tgataagcat
    45901 cacttcggaa ataggaacga tctttttgat tctttgtgaa atcttttggc agacgtcctt
    45961 ctttgatctc atgggcaaga ggaataatac tagaaccatc accttgccga taaatctgat
    46021 tgagttccat tttgggaatt tgttcgattt ccaaaagatc atggagtact tgaccaggac
    46081 cgacagaggg aagctgatct ttgtctccta ctaagataac ttgcatattc gtcggaatcg
    46141 ctttgaataa tgtgttagcc agccatgtat cgaccataga catctcatca acaatcaaaa
    46201 gtccgccttc taattctttc gtactgactg aaggtgtttt ttcccgtcca ttcagcccca
    46261 gaagacgatg gatcgtactg gcaggcagac ctgtcgtttc gttcattcgt ttagctgctc
    46321 ggccagttgg tgctgcaagt agaataggaa aaatttcttg ggtatatttt gaaggatcca
    46381 attccagtcc gttcaactct gcaaaaagat tgacgattcc gttgatcaca gtagttttcc
    46441 ccgtacctgg tcctcctgtt aaaataaata gaggggaacg gattgcttca gcgatagctt
    46501 gttcttgcga aggtccatac tgtatgccga atattttttc gatacgccga atattcttct
    46561 gcacttcttt ttcaggataa tggatttctt ttttacgact gagaaggcgc tggatcgaat
    46621 taccgatccc ccattcagaa aagtacaaac tgttttcgta aagattagtc tcttcttgtt
    46681 gtatctttcc ttcttcaaca agttggataa ttacagtagc aacctgatca ggctggattt
    46741 caattgggcg acttgtttct aaaatacgga tcgtttgctg aagcaatgtc tccgccggta
    46801 cgtatgtatc tcctgtttga actgcatgct gaaaaatctg atgcaagata gctgctcgaa
    46861 ttcttctcgg tgaatctgct gcaataccga tttgttcggc tagattatct gcacgtttga
    46921 acccgattcc ttctatgtct tcgactagct ggtacggatt ttcttcgatg atatccaaag
    46981 actcgttctt ataggcctgg tagatactga aagctaactg actaccgaac ccgtaacgat
    47041 tcagtcccat gatcacttga tccatcccgt ggtttagccg aatcgtctca gcaagcattt
    47101 ctctttttgg cttcgtcaaa ccggagattt gttttaatac cgaaggatca gcaatgattt
    47161 tttcgatagc atcttctccc agcaattcta caattttttc tgctgttttc ttcccgattc
    47221 ctgggaattt ttcgctggaa agatacgcta cgatcccatt tgcagttgtt ggcttttctt
    47281 gctcatatct ttcgagttta agctgccttc cgtatttagg atgatccact aattctccat
    47341 aaaaacgata agtctcattt tcttgaatat cgccgaaact tccggtgact acaatctctt
    47401 tttcacggta atcagctgtg gtttcactga tgtgtaccaa aagcactttg taaaaattac
    47461 taggattttg aaaaaaaatc gcggcaactg taccaacgaa ataaggcatt tcttctggct
    47521 gcatcggaag ccgcctcctt cttctatagt aaaggttctg gtgctgtttc agttcctaaa
    47581 aaatctgttt ggttccatac tttcagttca tatggcaata atctgcaagg ctcttcagtc
    47641 tctaaaatcg tcaaactact attgaacaat ccacccattt cacgcaactc acttagctct
    47701 tttcctgtca tccattgaat ggctgcagtt aaagaagctc catgtcctac gaataaaagt
    47761 gggccatctt tatgttgggc aaccgcatct gctacaacag tttcgatacg tgtgattgcc
    47821 gattcaatcg tttctccgtg aaaaggagaa ggatcataca gatctaaatg attacgcaaa
    47881 ttcggcagat tatccggata tttctggtac atttcatcga tcgactgacc ttctaaagta
    47941 cccagcccta gttctcttag cttatctgta taaaaaatct ctaccggacg agcaagctct
    48001 ttgttgatac cttctgctgt atcacgtgct cgctttgctg tactggaata aattgcttta
    48061 aaaggaacat attttacctt tttcccaaat gctttgattt cttcgtaact ttgtggcaaa
    48121 agcggagaat cgccattgct cccttgaaaa cgtctttcct gattccattg tgtcttccca
    48181 tgtcgggtaa aatatagttc catacgcagc aaactcctgt ctttctttta ttttactcta
    48241 taataaactg tctaatccag cttgtcattt tcatagtgat gcgtcaattc taaattaggg
    48301 aatccttgct ggcgaagtgc ttcatacact atcattgcag ctgtattcga taaattcaat
    48361 gagcggacat gctcatcatt catagggatg cgtaaacact tttcttcgtt ttcacgcata
    48421 aatgtttctg gcaaaccggt tgtttctttt ccaaataaaa agaagtgctc ttctccatca
    48481 gcaaaatttt cgtcactata tactttatgg gcaaattttg agatcaaatg tagtttacga
    48541 ttacctaaaa atgttaaaaa agcttctaaa ttactgtggt aagtaatatt tacatcattc
    48601 caataatcca accctgcccg ttttagatgt ttgtcatcag ttgaaaaacc tagtggctcg
    48661 attaaatgaa gcggagtatt cgtggctgca cacgtacggg caatatttcc agtgtttgca
    48721 gggattaatg gttcaaataa aacgatatga ttcatcagga tcattcctct catatttatg
    48781 ttcgtttcta ttttctgaca atttgatttt tgcataaaaa aaaacgtatc aactcggtgt
    48841 cagtcactgc gagtcgttac gttagtgaag ctcttctcac taacttttat cagaacagga
    48901 acctgataaa aaccaatgaa aaaacaactt gttgctaata taacaccctc aacttttttt
    48961 tgcaacctct actcattaaa aactgctaga aaaacgtttt ctcttagttc cttttaataa
    49021 ttctatgtca attgtaatct tcttcaaagg attcttatat aagtctgctt tgattcgctc
    49081 ttctacctgc cattctaaag gtgacatggc caaaagatct ttttgatttt cctctggtat
    49141 ctcaaattca taggttacac gctgacgttc agttaatttc attgcttcag caaacttggc
    49201 tactacacgt tcattggaat aactctgttt ttcaggttga ttcggataaa aagcctgacg
    49261 tagttccttt aaataatttt cttgtggcac caccttcaac acttctccat cttctgagag
    49321 tacacgttgg aattcttggt aatgagaagg cgaaaagata tttaaaaccg cgttgaatgt
    49381 ttgatcagca aacggcaaat tggtcaaatc agctacacac caaaatgctt cggcagattg
    49441 ttctgtagct gcgtagactc cttcttttga aatatcaaat ccaacagcat tttgaatctt
    49501 tttcaatttt gaaagttcat tcaagaagct accttctccg cagccaacat ctaatagcga
    49561 gacttcttca ggtaaatgct gcgcaatagt ctcaataacg ggctgataca tgccagattg
    49621 gatcattcta cgccttggaa cgaacattcc ttgatcgtat tctgttttaa ccgcatggga
    49681 taaaaaataa agtgttcctt ttttggaaag gtcaaaacgg tgattatttt tgcatatcaa
    49741 gccattatca gactttttta cttcttcttg gcaaaccgga cagcggaaca gctgatgatt
    49801 ttctgccaaa aactggcgtc ctcggtcaat tttttttaac atagttcccc ctcatttctg
    49861 ttttatctta ccgttagatg ctcactttgg caactgctaa aaatatgata caatgcctag
    49921 aagaaagtga aagataaagg agaagattag atgatcaaag aattttgcgc tgaaaactac
    49981 acatctattc ctctagcaat tgctagagga gccgatcgga tcgaattgtg tgacaactta
    50041 gcggtcggtg gcacaacccc gagtactggt gtgatcgaag aaacgttaag ttatgctggg
    50101 gaaaaagata tccccgtaat gacgattatt cgtcctagag ggggcgactt cgtctataac
    50161 gatatcgaat tgaaaatcat gcatactgat ttgattgaag caaagaaatt agggacggat
    50221 ggcgtagtat ttggttgtct tactccttca ggctggctag acgaagaggc cttagaacta
    50281 ttgatcgaaa cagcagaagg gttgcagatc accttccata tggcttttga cagtattcct
    50341 gaagatcggc aattcgaagc aatcgattgg ctggtagaac atggtgttga ccgtatcttg
    50401 actcatggcg gtcctgctga caaaactatt gtagaaaatt tcccacggct taaagaattg
    50461 attgcctata cagatggccg cttaatcatt ttgcctggtg gtggtgtcac tgcagagaat
    50521 gcagcacatg tagctaaaga attgaacgta agcgaagtac acggaaccaa aatcgtggat
    50581 cttcagttat aatcttataa acaaaaaaac atttgcaaca ggcataatgc ttattgcaaa
    50641 tgtttttgtt tttttacata aaatagccca taaataaaga agcaatattg aaataaatca
    50701 gtacactcgt caaatcgctc aaagtcgtga taaagggacc gcttgctact gctggatcaa
    50761 atcctagacg atccattagc atcgggatta aactacctgc aagattcgcc actgtgattg
    50821 caaatagcat agccatccct atgacaaacc ccaagataaa attatgtttc caaaaaccta
    50881 cgattagaaa aatcgtgatc cccgtaacag ctcctgtgac aacgccggtc aagacttcag
    50941 ccaaaacaag tcgaacaaat ccatgatctt tctcatcaga aatcgcaagt cgacgaacag
    51001 ccacagctag cgactgggtt ccagcattac cggcagttcc tgtaatcagc gaaatgaaga
    51061 ctgctaaaat actcgcttca cttaccaagt cttcatagtg actgattaaa gaagcggtcg
    51121 acatacctaa aaacaacaga gtgatcagcc aaggcaaacg tcgagacgct gcctttactg
    51181 gattttcatt aatttcttcc acattgaccc cggcaagtcc tgaataatcg ctagcagctt
    51241 catcatcaat aacgtcgatg atatcatcga ctgtgacgat tcctaacaaa tgatcatcat
    51301 aatcggtaac aggaagagct aagaagtcat aatctctaaa tgtttgtgcc acatcttctt
    51361 ggtcgtcgcc tacatgaact gaaagcactc gttcgctcat cagatcagaa atcattgcgt
    51421 cgtcatcatt cacgattagg tcgcgcagag aaataacccc tactagctga ccttcttgat
    51481 taacgacata gatgtaatag attgtttcag ctacatctgc ttcgttcttc agcacgtaca
    51541 tcgcagagcg aacagtttga ttggctacga tcgaaacaaa ttcagttgtc atgatcgcgc
    51601 cagccgtttc atcctcgtaa tggagaagtt ccttgatttc actggcatcg tctgccgaca
    51661 tcaaacttaa atatttagca atttgctttt tatccagcgt attaagcaag tcaacagcat
    51721 tatctgtata catctcagaa agcatatcag ctgcatagct aggacgcatt tcatctaggt
    51781 attctttcat atgttcgttg tcttcttcaa tcacatcgaa catatccgct aattctttag
    51841 gcgacagata ggaatagatc agctgcctgt tctcttctgt aagagattgg tagaattgcc
    51901 cctgctcata gatatgcatc tctaaaaaac tgtttctgaa tgcctgaata ttattttccc
    51961 ttaaatcttg agtcaactgg gcaaatcttt cctctaattc ttgattttca tccaaaccaa
    52021 tctcacctcg ccttattctt caaaccgtct cacaactgcc tccatgtctg cggctaaagg
    52081 ctgcttgaac tccagcaact cttctgtaaa tggatggtaa aaacgcagat cataacaatg
    52141 aagggcttgt ctttttattc ccagatccat tcgcccgcca tacatatcat caccgagcag
    52201 ggcacagcca attgcggaaa aatgaactct tatttgatgt gtccttcctg tatgcagctg
    52261 gatatcaact aacgcgattt ctgttagtcg cttctctatc cagtactcag tctgtgccga
    52321 acgtccttca tcagagacca ttcgcttcaa tagcgaagaa taatctcggg cgatcggcaa
    52381 atcgatatgt ccatgtgccg ataaatctga aagccttcca ctgactaagg cctgatattt
    52441 tttcacaaac ttcttttcac gaagttgcat atctaatttt gcgtgcgcaa atccatgctt
    52501 tgcaaaaagc atcaaaccag atgtatcccg atctagtcgc gtcaccacat ggattacttg
    52561 gttttcgtaa ccttgttttt tataataagc ctttacacga ttagccattg tcccatttgg
    52621 atggtattgg gcaggaatag acgaaacgcc tgctggttta tttactacca gaacgtgttc
    52681 atcttcatac acgatatcga tcggtgtttc atccaaaagt acggtttcat gttctccttc
    52741 agcaggaatc acaatggtta ccttatcatc cttagctaga gaaaacaaga cattttctac
    52801 ttgatcatta actttgattt gaccgccttg aaattttatt ttcgctaaca gaccctttga
    52861 gatccctttt tcttttaaaa aatattttac ttgctgagaa tgatctttct cataatccca
    52921 tgtaaactgc atatcaatcc tcactaataa aggcatcttt cacacgatgc caaaaatgca
    52981 tatgtcgata agaagcaaaa tggatccgtt cttctgctat tcgataataa attgagcgga
    53041 tatttgcttt tgcgacattc aattgatcaa ccgttacaag ataatcttct gtattttcca
    53101 attttatttc tagccattca tcatgggcaa tcacgatcgg agaacccaaa gtacgaaaca
    53161 ctcgattatt cagtgaagca atctctgcca actgaaaggc attgatacta ggatggatca
    53221 cagcaccgcc gacactttta ttatatgctg tcgaaccagt aggcgtagaa atcgtcaatc
    53281 catctcctct aaaactttca aacagctcgt ttttgatgta tacatcggct accatcgtac
    53341 gattggcccg tttaatcgtt gattcattca gtgctaaaaa atgctggtcc ggtgtttcat
    53401 ccaaataact gatccgaaca tccagcaagg gataactaac actttgttcc cggttcgttc
    53461 gtaagctgtc tactagttct tccagctcgt aatcccgcca atccgtgtaa aaccctaaat
    53521 gacctgtatg cacgcccaag aaacgcacat cattcagaca atgactgtag tgatggaacg
    53581 ccgacaataa tgtgccgtct ccgccgactg agatgaccaa ttctggctca tgatcatctc
    53641 gttgaatccc tgcttgttct aaaagtgcgt tcaaacgttc tgtcacttct atagtctttg
    53701 cttctttatt atgaacgatc gctactttca tcccctgcct cctctctttc gctttctttc
    53761 ttcaaaagcg ttcgatagta gacatcatct gattttcctc ttccatggga gaataaccgc
    53821 tgtgcttctt ggatttcttc acggatactg gacatctctt catccaactg ataggcagct
    53881 tctgccgcac gctgaagtcg ttcactcatt tcttctggaa aaacgccttg atatttataa
    53941 ttcagcgaat gctcaatcgt tgcccagaaa ttcatcgcaa gagtccgaat ctggatttcc
    54001 gccaaaattt tcttctcacc gctgatcagc tgtacaggat actcgatcac cagatgataa
    54061 gaacggtagc cacttgcttt tttatttgtg atgtaatctc gttcttggag aactttcatg
    54121 tcttttcttt tacggatgat ctcaacaact tgatggatat cttctacaaa ctgacacatg
    54181 atccttaacc cggcaatatc agacatttct tcttctaaac gtcccattgg aatatgccgt
    54241 aattgtgatt ttgttacaat actatcgact ggcttgactc tcccagtgac aaattcaatc
    54301 gggacatgtc gattttgttc acggaactgt ttgcggatcc cccgcagttt cactttcaat
    54361 tctgatacag tttgttcata tggtgctaaa aatgcttccc aatctcgttc catagctgat
    54421 acctctactt cattaacatt cattgtttat tctaccatat atgcaaagtt ttttcgtact
    54481 cttgatttat gcattgacca aaaaaagaaa attaggcaaa atagacaaaa aggagtcgat
    54541 caaatgacac aaatgcttga aatcgaatat aaatctatgc tgacaaagca agagtacgag
    54601 atattcatcg ctcactatca attaacagat aaagatttcc gtgtacagac taatatttat
    54661 ttcgataccg ttgatgaaca gctgaagaaa caaaattgtg gcctacggat ccgtttcgtt
    54721 ggtcatcaag ctgaatatac attaaaaaca cctgctgaaa aagggcgtct cgaaacaacg
    54781 gataccttta taacagaaga agcagaagca tttatcttcg aaaaacgtct gcctcgttca
    54841 ggcgcagttt ttcaaaaact ttctgatttg aatatcgatc ctgcttcatt aatccaaacc
    54901 ggaaagctta caacaaaacg ggctgaattc cctattgaag aaggactttt agctattgat
    54961 gaaagctggg gagacaatct acacgatttt gaactggaac tagaggtaag gggatgcatc
    55021 tgtgggaaaa attgctttta taaatttttt aaaacgtttt tctttacctt atcgtcctgc
    55081 taagaacaag atccaacgta tgcttgaagc taaaaattag aaacctttca ttttcacaag
    55141 gcacttgagt tcattttttt acttttttct gttaagttat aggatgtgaa agaatctagt
    55201 cactagttgt atagaatcta ttttggggga gattcatatg atcgaaatct atttatttgt
    55261 taatccttta ggggaatact gtttcgaaat ggaacaacag ttattacaat ttatcgaaga
    55321 agagtacggg acaccatcaa aagaaaagat gcaatttcgc tttcttcctt tggtcaattt
    55381 gcagacaatt ggggatgtca tgcaacaaaa aggaatttct cagaacaatc ttgaggaacg
    55441 taatcactta ttctcaatga cttattctgc agcattggac tgcaaagcgg cgcagtttca
    55501 aggaaagaaa aaaggccgcc gttttttgat caaattgcaa gaagcagtcg gctgtaatga
    55561 cataccatat tctcaagaac ttgctgaatc catatttgaa gaaatcggcg gcgatttgaa
    55621 tatgtttaaa gaagatcgtc agtctgactt cgttaaagaa gtattctttt ctgatcaaaa
    55681 aattgctcgg gaaatgggca tcacaaaaca cccttctgca gtcgtttaca attatgcctg
    55741 cgaccgtgat tttggtgttt tagtagaagt aaaaggtaca agtagccttt ggagaatcac
    55801 agagctgtgt aaaacaacag ataactcata tcaagttttt aatggtgaac atttacatac
    55861 aaatgattct cagttccatt caagaactag ccatttacac ttgctttcta attaaaaaaa
    55921 tacgtcgact cccttacaag agagccgacg tatttttttc gtttctattc gagaaaatca
    55981 aaaatagaaa gccttataaa cgatcgatca attcttctaa ttcatttaga cgttgttcaa
    56041 acatcgacat tgcatcttca atatatgcag cctgtgtcat atcaactcct gcttttttca
    56101 ttacttccac aggataatcg ctgttacctg cttttaggta agccaagtag ttctctagtg
    56161 cctctggttc ctggtttagt attttcttcg ccagtgctga agcagcagaa aagccagtcg
    56221 agtattggaa aacatagtaa ttataataaa aatgcggtat ccgtgaccat tcgaatttaa
    56281 tttctgggtc ttcttcgact gctggaccat aatattttgc attcaattta ccataactat
    56341 cacttaggta ttcactagtc aatggcacac ctttttcatc ttccgtatgc atgaaatgct
    56401 cgaattcagc gaattgtgtc tggcggaaaa ctgttccttt aaacccatcc aagtaatggt
    56461 tgagtacata agcccgtaca cgagggtctt tttctgtttc caataaatac tccgttagga
    56521 tattttcatt cgttgtcgaa gcaatttctg ctaaaaagat ggagtagtcg ccgtacacat
    56581 aaggctggtt cgaacgagtg aaataactat gaacactatg tcccatttcg tggacaagcg
    56641 taaatagctg atccagcgta tcatgccaat tcaataaaat atatggattt gtgtcatagc
    56701 ttcccgaaga ataagcaccg cttcgtttcc ctttattttc gacaacatcg atccaacgtt
    56761 cagagaatgc tttttctacg atggccatgt attcttcacc cattggtttc agtgcttcta
    56821 aagctttttc ttttgcttct tcgtacgtaa aggtaattgg agcttcccct aagaccggtg
    56881 tataaagatc atacatgtgc agtttttcca cttctaataa acgtttccgt aattccatgt
    56941 atcgatgtaa caaaggcaaa tgcttgttta ccacgtctac caaagtatcg tatacacttt
    57001 caggaatatg attattgctc aaagacgctt ctctggcaga gctgtaatta cggactttcg
    57061 ctttaaaatt atgtcctttt atatgtgtgc ctaaagtaga agcaaatgta tttctaaatt
    57121 gttcgtaaac actgtacaat cccttaaatg ctgcttcgcg cacccttcga tccgtgcttt
    57181 ctagcaactg accatacacg ccatgagata attggactat ttcaccattt tctccttcaa
    57241 tcgttggaaa aactagatct gcattattca aaacagcaaa tgtatcactt gaagcatcaa
    57301 agatttcacc tgctccagca agaagagatt cctgctcagc agataagaca tgggctcgat
    57361 tatctactat ttgctggata taatggcgat agacttccaa ttttggttct tctttgaaat
    57421 attgccaaat ctggtcatct gacaattgca atatttctgg ttcaaaccag gaaacggctt
    57481 cactaacttt cgaaaacaga ctgcttgctc ttgcataaag cgcttggtaa tctgtatttc
    57541 cagtgtcttg atcgttttta aggtgcgcat atacataaat gacttcagtt tggcgataaa
    57601 ccctcaatac gaattcaatc gcatttaaaa attgagaagc gccttgatca agtgttcctt
    57661 tgtgtttttc agattgtttt aactcttctg ataattccaa atatttctca tcaaactctt
    57721 ggtcgcttga aaagatcttg gtcaagtccc aagttaaatt ttcaggcaat tcttctcgtt
    57781 ttggcaactg ctttacttcc atgaaatcca ctccttttct tcccttagct ctatctatca
    57841 aaatagatca tagtctaaca tccacatgtc acagcatcta acttttctac tcattcatgt
    57901 gtctgcttcc atcaatttta gcataactaa atcttgtttt acatagaaaa ccgattccta
    57961 gcctattttt atacttacta ttttttcaaa gaagacaagt gtatgcattc gttaaaaaac
    58021 tgctgataga ccatctcttc atcaatcata ggaaaaagcc attccctttt atgttctttt
    58081 atttggcaaa gccatgagtt gaaatcagga actttctggt tttccaaggc ttcttcgtac
    58141 aacattcgat aaagaaaaac ctgttcttgt aaataaaaga aaaaccgact tttttgatag
    58201 atccacgatg atagatgcaa aagatgttta tgacgcaagt agcattgttc ttgtatggat
    58261 actgtattct tttgcttgtg aataagttgg cgtgtcagcc atttcttccc atcttcactc
    58321 actttttcta tttttttcat ttggttcatt ttaatttcgt tactagtgaa tatttcttta
    58381 aggtccctac tagaaaaagt ccagcagcta ctgcaaaagg aaatatgccc tgatacagtc
    58441 tctgtaatat gatgatacaa ataaagcttt tgtttcttga gatcagcttt ccagcaatgc
    58501 actcctcttt ttctattata gtagcagcaa cttttttcta tcaatgagaa ttgcgattgt
    58561 ccaagaaaag aattaccaag tatccaccat acttggtaac tgttattcaa ataattttgg
    58621 gttctttcaa taaatctctg gtgagacagt ctagaacatt ggatttctat tgctagattc
    58681 gccaacaaaa tatccggcct ttgccgcaac ctcggcaaat aggcttccaa aaatactggt
    58741 tctactgact gtcccagcca atccatgaag cattccttta actgtaagtg ctcttttgat
    58801 tctctttcac taaagaccga acagttatct gatttttgat gggcaaaatg agcacatttt
    58861 ttctttccct ttttcaaaat cactcttttt cgacagccac gacaataata tttctttcct
    58921 ttttctgcat gtttagcaaa acagcactta ttatattcat tcattgcaag cagcattttt
    58981 ctccctctga acttatttac gtctaagaat ttatttacac gaaaaaagag ggcgtgaaaa
    59041 agctattctg catcaagtaa taagaacagc taaacaaaaa tagttcccaa tatttttcgt
    59101 ttggttgggc ttgttaccgc agatgcaagc ttttgaacac atttatacga aaaaaagact
    59161 gcgacacaat ttttgtcaca gtctcttact ataatgctga tttatacaaa ataaaatttc
    59221 gttcgctcga tagcattacg cgccatcaga cattgtccat attcattcaa tgtttctggt
    59281 gtacgatcgc tcttttcagc aaactccaaa attcgagcaa tctgattctc tacatccgct
    59341 tggttgagat tttccatcca gaagtgaacg actaggtaat agcgctcttc gaataaatac
    59401 aaatcagtcc aagcagactc tagttcgaca tctgttgcaa gttggatcac ttgttcaaaa
    59461 tcttcaaaag caaaagttgc ttgtctttcc tgttcttcta gggcgcttcc agataattct
    59521 tcctccggat cgctgccaat aatctgctga cgaagaaagt cactcacatc ttctgaatca
    59581 acagtagaat cttctgattg agaaatttct tcatccggaa gatttttact gataaacagt
    59641 tctaatccgt ctccttttgg caaaacttgg aaagtgacag cttcgcttcc tcggaactcc
    59701 tcttcgatat caacttcttc caaaatacta taaaagaaat tttcgatttc tttgtgattg
    59761 ccaagtaaat ccaaaaatga aacgccccgt tcctctaaat cttcatgacc aattagtaca
    59821 cggatcgtat tttcattaat atgttccatt tccattttgc tacacctcac tttgccacaa
    59881 tgtttaatat agattcattg tagcgaaatc agcttaaatg taaagaaaaa aaatctcgct
    59941 gttaagcgaa tttaataaaa ccagcggatt tttcaacctt tcaagctatc ttatttaact
    60001 ataacatttt tggcagacga atactatata gccgactttt cagctaattt tccctctcta
    60061 tttttcgtgc aatcatcatc ttctactacc tttttataca tctaatcaag aatacttttt
    60121 gtaaaaacaa aaaaacttgg aaaaactatc tttgtaatag tcttt
//
LOCUS       DAPBAF010000013        57071 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.013, whole genome shotgun sequence.
ACCESSION   DAPBAF010000013 DAPBAF010000000
VERSION     DAPBAF010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 57071)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57071)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57071
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.013"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(<1..132)
                     /locus_tag="RD451_000930"
     CDS             complement(<1..132)
                     /locus_tag="RD451_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HDT7566210.1"
                     /translation="MFSDKEVLLKSLHVCLKLPIVVFNSEFSIIKEYRSDRTTYFFYD
                     "
     gene            826..1212
                     /locus_tag="RD451_000931"
     CDS             826..1212
                     /locus_tag="RD451_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDT7566211.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFDKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
     gene            1306..1497
                     /locus_tag="RD451_000932"
     CDS             1306..1497
                     /locus_tag="RD451_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7566212.1"
                     /translation="MNSLKEDFILAKAGNEEAVEAILKRFSSLIHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
     gene            2011..2343
                     /locus_tag="RD451_000933"
     CDS             2011..2343
                     /locus_tag="RD451_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDT7566213.1"
                     /translation="MRKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            2639..2794
                     /locus_tag="RD451_000934"
     CDS             2639..2794
                     /locus_tag="RD451_000934"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HDT7566214.1"
                     /translation="MPTVIHSDRGSQHRSFIYQELLNDHHITHSVSQTGTPVDNAVIE
                     AFHRSIK"
     gene            3070..4410
                     /locus_tag="RD451_000935"
                     /pseudo
     CDS             3070..4410
                     /locus_tag="RD451_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(4651..6267)
                     /locus_tag="RD451_000936"
     CDS             complement(4651..6267)
                     /locus_tag="RD451_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HDT7566215.1"
                     /translation="MKKIPITILTGYLGSGKTILLNHILYGDHGKEIAVIVNDIGEVN
                     VDGVLVDKKGFKRTGEKLVSMPNGCICCTLREDLIVELDQLVQFSDLNQIVIEASGIS
                     KPIPIIQAIILAKNPLDIDLTQRLEIGAIIIVVDVKRFWDNFETGEKIQERKAEGNVV
                     EEEQDIRGLLIDQFECCNILLLNNSDLVSTKTIYKINGLIAKLQSNAKIIRTIKGEVD
                     LSKILNTNLFNIDETSYSVGWFKELELGYQNHIPETEEYGISSFIYRNRLLLDAQKFA
                     HLTDKNFPGNITRAKGFLWFAQHSDFSTIFETSGSYKSIESLNYWVASLPKIECQMII
                     QKNPELKEAWHPLFGERINKLVFIGMKMDQQCIKEQLEGCLTDSLNADNFRKISPFPW
                     KKSNMFSQISLMKFLRKAGVKIGDVIIIGILIITSFIPLFVFSIEKENETTEDAIKYA
                     IVRIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVRTGW
                     ISKPGQTSICLPHKLVISIEKKESTDYYIY"
     gene            6385..6603
                     /locus_tag="RD451_000937"
     CDS             6385..6603
                     /locus_tag="RD451_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7566216.1"
                     /translation="MSQYRHLTILERERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTIHLPKRKKIMLIEEKNADVITF"
     gene            6798..7259
                     /locus_tag="RD451_000938"
     CDS             6798..7259
                     /locus_tag="RD451_000938"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HDT7566217.1"
                     /translation="MHHRGKTRHTKNHVESRGKICLTHSIHGRPKSADDRSDFGHWKA
                     DIVAGKTGGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITP
                     DRGKEFSNHFAVTEALNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(7452..7691)
                     /locus_tag="RD451_000939"
     CDS             complement(7452..7691)
                     /locus_tag="RD451_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7566218.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYRFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(7715..9238)
                     /locus_tag="RD451_000940"
     CDS             complement(7715..9238)
                     /locus_tag="RD451_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HDT7566219.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLKQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKINKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNELHNWPTFYPASLSKHEIAQEMMAH"
     gene            complement(9256..9378)
                     /locus_tag="RD451_000941"
     CDS             complement(9256..9378)
                     /locus_tag="RD451_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HDT7566220.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKRNKMKKLA"
     gene            complement(9408..10391)
                     /locus_tag="RD451_000942"
     CDS             complement(9408..10391)
                     /locus_tag="RD451_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HDT7566221.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVMADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLKKFNHPLVFESDSSENH
                     YNGKYYHQHHQVHEFKSILLTSDQDIKKDFLLQWIDWLILTNQGSLYRFKGLIALQEQ
                     DFIVAMQEVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            complement(10415..10564)
                     /gene="rpmG"
                     /locus_tag="RD451_000943"
     CDS             complement(10415..10564)
                     /gene="rpmG"
                     /locus_tag="RD451_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HDT7566222.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            complement(10585..10962)
                     /locus_tag="RD451_000944"
     CDS             complement(10585..10962)
                     /locus_tag="RD451_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566223.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDAQQIQAYLEDR"
     gene            complement(10994..11173)
                     /gene="rpmF"
                     /locus_tag="RD451_000945"
     CDS             complement(10994..11173)
                     /gene="rpmF"
                     /locus_tag="RD451_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HDT7566224.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            complement(11188..11457)
                     /gene="rpsN"
                     /locus_tag="RD451_000946"
     CDS             complement(11188..11457)
                     /gene="rpsN"
                     /locus_tag="RD451_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HDT7566225.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKTAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            complement(11980..13746)
                     /locus_tag="RD451_000947"
     CDS             complement(11980..13746)
                     /locus_tag="RD451_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7566226.1"
                     /translation="MQMIGGLTMKSFYKNKFALSDQGAEALTKASISSFFVYCINMVP
                     AFIIMMLIDELVLENTKPRWLYFAVSFVTLLFMYWLLDREYENLYNSTYKESAHLRVQ
                     IADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVMLL
                     VGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEINS
                     FNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLLTG
                     EVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSPLK
                     SFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDYDE
                     GCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAARL
                     ANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLDAE
                     NEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKLVDQGTHNELYRRSEIY
                     KNLIKKTKLSEKFVYEKEAQSR"
     gene            complement(13706..15460)
                     /locus_tag="RD451_000948"
     CDS             complement(13706..15460)
                     /locus_tag="RD451_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7566227.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLQ
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQHLMKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHQVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            complement(15570..16139)
                     /locus_tag="RD451_000949"
     CDS             complement(15570..16139)
                     /locus_tag="RD451_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HDT7566228.1"
                     /translation="MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFGHSISPGIFGL
                     LSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVF
                     GYDRAIPQVASWALMQLGSAAGQWIPIWFFTDRFRQDWIDKGQSAATMDAMIHYAVGI
                     WGIISVLVVASLSMIGVLIGRKVLKKYKK"
     gene            complement(16157..17572)
                     /locus_tag="RD451_000950"
     CDS             complement(16157..17572)
                     /locus_tag="RD451_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HDT7566229.1"
                     /translation="MFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSGKST
                     LLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQDPRGQFFTTNTTS
                     ELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLSLNS
                     KLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKELIDQVLFVKNRT
                     VKTTTIQLLKTENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEITYENILKDINFDV
                     KVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKNLSSPFLVMQEMDYQFFTE
                     SVRSELALGNEIVSKDQQEKILKKMELYKMKDQLPFDLSGGEKQRLLVSIASLSKTNL
                     FLFDEPTSGLDYINMERIADLIKDLKEKGAVVIATHDPEFLYKTCNRIIYLKNGGIKK
                     DIKLRVEDSTLIEQIFNDITK"
     gene            complement(17583..18251)
                     /locus_tag="RD451_000951"
     CDS             complement(17583..18251)
                     /locus_tag="RD451_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HDT7566230.1"
                     /translation="MSKINPLTLITLNIFFPVIIFLGKGNIFQVGCFIIATVLVLMFR
                     KIKTCIYFILIYSVLFLVMKIIDAIKIEFFTIFFATSLYIVFRMLPVVMISWLLVSVY
                     TSNELLSSLEKIHLPKKIMLSITVVIRFFPTYRSEIRMIKESLKMRNIRLSFFQPLQY
                     LEFLLVPVLIRATMIAEEMTANAITKGIESPVKRSSYYKTNMSLLDYIILFSVTIFFL
                     SILI"
     gene            complement(18381..18965)
                     /locus_tag="RD451_000952"
     CDS             complement(18381..18965)
                     /locus_tag="RD451_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDT7566231.1"
                     /translation="MESGLSHFEKEGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINALINMYNEEFTKYLLNLENIDIEKSWRENFNELDPFINYIFENKRIFDLI
                     LFQSAGTKYQDIVEKITSFVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYAT
                     FYDILKHSYSKEKTMLLTRRLYQFSVPGWIELLS"
     gene            complement(19296..19529)
                     /locus_tag="RD451_000953"
     CDS             complement(19296..19529)
                     /locus_tag="RD451_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dependent repressor"
                     /protein_id="HDT7566232.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLAKLRYEDYLDIGFQLTDKGKKFIDDYKKGFK"
     gene            complement(19544..20494)
                     /locus_tag="RD451_000954"
     CDS             complement(19544..20494)
                     /locus_tag="RD451_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HDT7566233.1"
                     /translation="MMRKWKAVLGSLGILIALFIFGACSINSKDKDKVASNEKLKVVV
                     TNSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETG
                     GNAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKN
                     IEKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYF
                     SKAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDT
                     NIPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            complement(20491..21333)
                     /locus_tag="RD451_000955"
     CDS             complement(20491..21333)
                     /locus_tag="RD451_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HDT7566234.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVIVVLFFKELLIT
                     SFDPLMAKAIGMNVSFYHYLLMVLLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGASSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERSL"
     gene            complement(21335..22054)
                     /locus_tag="RD451_000956"
     CDS             complement(21335..22054)
                     /locus_tag="RD451_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HDT7566235.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKKLKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVES
                     VFNEENLKKAYGDTIFIGEGE"
     gene            22746..22904
                     /locus_tag="RD451_000957"
     CDS             22746..22904
                     /locus_tag="RD451_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7566236.1"
                     /translation="MNKKQTCAFLGIDNNTLDKWIRIYNFPVIRVGGVVRFDVEDIKD
                     FMNTFKIT"
     gene            22976..24202
                     /locus_tag="RD451_000958"
     CDS             22976..24202
                     /locus_tag="RD451_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDT7566237.1"
                     /translation="MPTKLSNGKYKTNLRYPKRFKEITGIASEKYQKTFPNRQLAIKA
                     ENDMKKKIEKVLREENANSLELKGKITFKKFYESKWLPRYELGQTIRSNRPPSDITIS
                     NTKDIFRLHILPMFGEYAMNYLNINTEIISDELTKKSKEYANIKIIKGYVRSMFDIAE
                     ILNYIEFNRTTKIIQSITAPKKNALEEKRIQEGKQALSSKELTNWIEAVNDDFNNHLL
                     TFHDYTLFMITLYLGDRKSETYALQWKYIDFEKQTVRLKHTLDKYQRKKFTKGRKDTV
                     IQVPEVVMTLLSEWKSVQADQLLKLKIKQTLDQYLFTYTKPSGEVNCPVHADYLNYRI
                     NSIKRRHPDLVHLSPHKLRHTYATIARQGGADMNQISNALTHSDISTTKIYVNTPDIV
                     DKAVFEAFQRGLNKCD"
     gene            complement(24290..24682)
                     /gene="rpsI"
                     /locus_tag="RD451_000959"
     CDS             complement(24290..24682)
                     /gene="rpsI"
                     /locus_tag="RD451_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HDT7566238.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(24698..25141)
                     /gene="rplM"
                     /locus_tag="RD451_000960"
     CDS             complement(24698..25141)
                     /gene="rplM"
                     /locus_tag="RD451_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HDT7566239.1"
                     /translation="MRTTYMAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPT
                     FTPHLDTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLI
                     ETSVKGMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            complement(25660..26127)
                     /locus_tag="RD451_000961"
     CDS             complement(25660..26127)
                     /locus_tag="RD451_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HDT7566240.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            complement(26247..27785)
                     /locus_tag="RD451_000962"
     CDS             complement(26247..27785)
                     /locus_tag="RD451_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HDT7566241.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            27865..28551
                     /locus_tag="RD451_000963"
     CDS             27865..28551
                     /locus_tag="RD451_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HDT7566242.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            complement(28752..29279)
                     /gene="msrA"
                     /locus_tag="RD451_000964"
     CDS             complement(28752..29279)
                     /gene="msrA"
                     /locus_tag="RD451_000964"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HDT7566243.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(29363..30040)
                     /gene="pgmB"
                     /locus_tag="RD451_000965"
     CDS             complement(29363..30040)
                     /gene="pgmB"
                     /locus_tag="RD451_000965"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HDT7566244.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            complement(30037..31167)
                     /locus_tag="RD451_000966"
     CDS             complement(30037..31167)
                     /locus_tag="RD451_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HDT7566245.1"
                     /translation="MRILIAPDSFKESLTALEAAQAIQSGFQEVFVQAEYDLLPIGDG
                     GEGTVSSLADSLRLKRQTAVVTNAFGKNKEIQYASDGQTAIFEMAEIVGLKDVPLNQQ
                     QPLRLSTRGVGELIRQLLQQGVRHIIIGVGGSSTNDGGIGMAEGLGYAFYDQDNQKVE
                     ALGENLGKIATVDKTNVPIELIKAKITVITDVTNLLCGKEGASFVFGPQKGLKENELA
                     VADQAMHDFYMRFAPQVIEASGSSAGGGMGAGLLAFASGKIVSGIDYVLDLLEFDKRV
                     QQADLVIVGEGRLDGQSLKGKAPVGIARRVPEGVPVIAICGSVGKGSEKAADVGISAV
                     FPILPAAVPLQEALQQATDNLHRTAKNIASLLQVVHFQGGNR"
     gene            complement(31167..33350)
                     /locus_tag="RD451_000967"
     CDS             complement(31167..33350)
                     /locus_tag="RD451_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HDT7566246.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            complement(33347..34372)
                     /locus_tag="RD451_000968"
     CDS             complement(33347..34372)
                     /locus_tag="RD451_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDT7566247.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTPNRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            complement(34417..35244)
                     /locus_tag="RD451_000969"
     CDS             complement(34417..35244)
                     /locus_tag="RD451_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HDT7566248.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            complement(35241..36308)
                     /locus_tag="RD451_000970"
     CDS             complement(35241..36308)
                     /locus_tag="RD451_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HDT7566249.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKYGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLRGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            complement(36334..37170)
                     /locus_tag="RD451_000971"
     CDS             complement(36334..37170)
                     /locus_tag="RD451_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDT7566250.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(37167..38036)
                     /locus_tag="RD451_000972"
     CDS             complement(37167..38036)
                     /locus_tag="RD451_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDT7566251.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(38106..39389)
                     /locus_tag="RD451_000973"
     CDS             complement(38106..39389)
                     /locus_tag="RD451_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HDT7566252.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            complement(39403..41088)
                     /locus_tag="RD451_000974"
     CDS             complement(39403..41088)
                     /locus_tag="RD451_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphorylase"
                     /protein_id="HDT7566253.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGTRVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            41363..42388
                     /locus_tag="RD451_000975"
     CDS             41363..42388
                     /locus_tag="RD451_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDT7566254.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            complement(42983..46657)
                     /gene="rpoC"
                     /locus_tag="RD451_000976"
     CDS             complement(42983..46657)
                     /gene="rpoC"
                     /locus_tag="RD451_000976"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HDT7566255.1"
                     /translation="MKWREPLLIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYR
                     TLKPEREGLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHI
                     ELAAPVSHIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTER
                     EYREKREQYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLD
                     ILEAFRASGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLK
                     RLLDLNAPGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRF
                     RQNLLGKRVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKN
                     AKRKIERQEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVC
                     EAYNADFDGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYY
                     LTMEEEGREGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMI
                     TTVGKIIFNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKK
                     KNLGNIIAEVFKRFKVTETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIEN
                     AHKQVETITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSG
                     ARGNISNFTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTA
                     LKTADSGYLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTR
                     KEVRHPETNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNL
                     ATGSDVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNP
                     KGQAVITEVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGA
                     PLTEGSIDPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRV
                     MDPGDTDILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAAS
                     FQETTRVLTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVY
                     SISDIEAQMAAEDAMNNQTK"
     gene            complement(46715..50332)
                     /gene="rpoB"
                     /locus_tag="RD451_000977"
     CDS             complement(46715..50332)
                     /gene="rpoB"
                     /locus_tag="RD451_000977"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HDT7566256.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLSALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            51060..52028
                     /locus_tag="RD451_000978"
     CDS             51060..52028
                     /locus_tag="RD451_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDT7566257.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            52046..52951
                     /locus_tag="RD451_000979"
     CDS             52046..52951
                     /locus_tag="RD451_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7566258.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGGAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            52948..53754
                     /locus_tag="RD451_000980"
     CDS             52948..53754
                     /locus_tag="RD451_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDT7566259.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            53890..54879
                     /locus_tag="RD451_000981"
     CDS             53890..54879
                     /locus_tag="RD451_000981"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HDT7566260.1"
                     /translation="MGKELDAMTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKA
                     IKELEKAGYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMLTSESTMKDVK
                     LAAAQGDSVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTII
                     AASACVKAIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLN
                     FSVPQNHFPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKS
                     FVLGKTVSFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(55196..55720)
                     /locus_tag="RD451_000982"
     CDS             complement(55196..55720)
                     /locus_tag="RD451_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF664 domain-containing protein"
                     /protein_id="HDT7566261.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            56007..>57071
                     /gene="scm"
                     /locus_tag="RD451_000983"
     CDS             56007..>57071
                     /gene="scm"
                     /locus_tag="RD451_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HDT7566262.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSS"
BASE COUNT        17284 a        11521 c         9693 g        18573 t
ORIGIN      
        1 atcataaaaa aaataagtag ttctatctga gcgatactct tttataatac tgaattcgga
       61 attaaaaacc acgataggta actttaaaca aacatgaaga gactttaata agacttcttt
      121 atctgaaaac acttttgttt ctctctttcc tttctacatc attaaatagt attttatacg
      181 ttatctaaaa tactattcct ctgtcaaaat aagctaactt acttcattat aaaatatcca
      241 cttatcgctt tcatgtatat tccaccgtaa aaagtacatt ttatcaccga gaactcatca
      301 tttttcatca tgatgaatac tatttacata tatctagttc aaagacaata attattatga
      361 tccgttatta tctaagcact atacagataa taggaatttt tcgtttctaa atattccaat
      421 ttgggaatcc aataaaaatt ttcgttcaaa tacgtgtcta ttcgaactct tttctagttg
      481 ttaattatga agggggaaga aataaaaaat acaatctata cacgaataag aatattatcc
      541 aaaaggaggt tttagaaaag atttattata cgtaaaaagc tcaagacatt ttcttagcca
      601 taaggacatg tttgatattt aagaagatat atgaattttc ttttctaagt ataaagataa
      661 ctatccatta tcaactaaaa aaacattttt gaaaataaac atcagcagtc ctatcaatgc
      721 atgtgagctt atagaagtta ttcgcagcgc agcataattg cattagcttc ttttcgtgtt
      781 ttttgcctct tttcccttta aatcttaatg gaggaggtgt gcaatatgtc agataacgac
      841 gaacgcgtaa atgcccagtt gattcgattc tttgaaaagg tcattttgaa caccgctaat
      901 acttattata aaaaacaaga agaaattcaa aaacatgaac aacttgatca actcccacca
      961 tatttgttta ctaaagatac tataaaattt aaacaaccga ttaatgtttt aaatgtgact
     1021 ctccttgttg aagatataaa attagcaaaa atccttcctt tgttgaaaga acctgaacaa
     1081 atttttctta tcgaaaaatt tatctttgat aaaactgata aagaaattgg aaaggttctg
     1141 gggattacaa gacagggtgc gacaaattta aaacatcgac tttacaaaaa aattcaaaaa
     1201 atgctggttt aatatctgca taataactaa ttttgtatgc ttctttgctc gttctcctcc
     1261 ttcccaaaga aatagattat aagtccatgg gaagaaggta gatttatgaa ttctttaaaa
     1321 gaagatttca ttttagcaaa ggctggaaat gaagaagctg ttgaggcaat tctcaaaaga
     1381 tttagctctt tgattcataa gcaatcctgg agaactggaa aatatgatca agattgttat
     1441 caagaatgta tgcttgcaat atatctagct atctcgaaat tcgaaattaa agaataactc
     1501 aactaaggga gtctgtgaca taagtaaaaa gatagtttca aatttcgaac aataaatttg
     1561 aaactatctt ctttataatt ataaagtatc gattttacag cgttctataa tgattcatag
     1621 aatctaaaac gaatgatttt aattatcaac gttttttaat tcgtttttag cttaaaaata
     1681 acttttgtca cagtctcact cctaaaatta ctttatttac gtatgaagtg ggcaggaggt
     1741 cgaatccaga actgggctat ggtacttcaa cgaggacttc tcctctagaa ttgaaaagca
     1801 tgcgatttac cttccgtaac gacggtagat ttattcaact atgtgtccaa tcaaaatttg
     1861 tctgatttca aaaatagtca agagaatttt ggttgttaaa aactcttatc tatcaacttc
     1921 cacagtttag ttgacaaacc ctgatactaa gttgggctat gatacacttt tcttgactat
     1981 cagttacgtt accggaagga atgaactcta ttgagaaaaa catatgatcg taaatttaaa
     2041 ctaaagattt cacaggatat ccttgagaaa aaagtaacta ccaagaaaat tgctgaagaa
     2101 tacaatatct ctcgtccaac aatttcccga tgggtttcag aatatcgtcg atacgggaaa
     2161 aatgcttttg ctggacaagg aaaaagatta cctgataaag cagatttcta cattcttgaa
     2221 caggaaaata aacgactaaa agaggaagac gagtgttcta cgaacacaaa gatcgatacg
     2281 gatctccagg gatcactcaa aaactttacg atgaaggaat cgaaatcaat aaacgtgttg
     2341 tagctgttct tatgcgtgaa atgaatttat gcacaagagg atttcatcga cgcaaatctt
     2401 ctcatggtag agaaaaaaca atcaaagaaa tggtaaaaaa atgttgaatc gataatttga
     2461 acagaaccaa attgatgctg tttgggtgat ggatattact tacattccat gtaatgacgg
     2521 tcgcctctat ttgtccacct atattgactt agcaactcgt attctacgtt actatatggt
     2581 agattcacac atgaaaaaag agattgtcgt ccgtccatta caaatttatt aaggagaatt
     2641 gcctacggta attcattccg atagaggtag ccagcatcgg tcttttattt atcaagagct
     2701 gttgaacgac caccacatca cacattcagt gagccaaact gggactcctg ttgacaatgc
     2761 agtaattgaa gcgtttcatc gatcaatcaa atgagaatta atcgactcca acaaatataa
     2821 aagtaaaata gagatgaagg tgttaatcca agattattta gaagactact acccaaacaa
     2881 aagaatccat acaaaattta tgatgactcc ttgacaattt gaagcgaaga aaataaggga
     2941 tctataatat ctagtgttgg tgacgccttc tgttgccaat actttttctt ttttctaata
     3001 aacgcaaaca gacaccttaa aatcctttag aataaagtcg acgaaaacca ttcaaaggag
     3061 tgtttcaaga tgtcctattc agagtttacc aaagagttac tagatattct agacctaaat
     3121 cttatctttc atgaagatgc ctttcgcaaa gagcgaatca atgacgaaac atgttttgtt
     3181 tttgatggca cattgaccta tcaaccggag gaatgctttc atcgccacta tcaaaatgaa
     3241 caaacgatca ttaaataggg ctggaaaaaa gtatccatct tattgaatga tgtcagtaac
     3301 tacaagacca ttctgcggat taacaaacag cgcttcaaat gtaaacactg tggaaagact
     3361 tttttagcag aagattcagt tagtgatcgt cgctgctcca ttgctcgcag agtcaaacaa
     3421 gccattcttg agctattaag cgaacctctt tctatgtctt tgatcgcacg tatgaagcac
     3481 atttctccga ccactgtcat tcgaatactt cgcagccttc ggcctaaaac catttctttg
     3541 agccagctgt taccagaagt ggtgtgtttc gatgaattca aatcagtgaa aaatgtctcg
     3601 ggagccatga gctttgtcat gatggacggc aagacccatc aactgattga tattgtggaa
     3661 aatcggcaac tcaatccttt acgcgactat ttcttgcgct accctataaa agtccgtgaa
     3721 caagtgcgtc tagtggtttc agatttctat acaccctatc gcacattggt gaaagagtgt
     3781 tttccgaatg cccgaatcgt cgccgatcgc tttcatatta gccaacacat tggtcgggct
     3841 tttaccaacc accgaattca agtaatgaag acctttaaaa aaggggatcg tcggtcgaag
     3901 cacttaaaga aatactggaa actacttcaa aagaatgcgt gggaattgaa aggtcagcat
     3961 cgctactggc gtccgtcatt tcgagatcat ctgacagaag cagagatagt cgatcggcta
     4021 ttatcttatg atgattcctt aaagcgaggc tacgaagtct accaggattt tctttccgtt
     4081 atcagaagac aagatgttcc tgaattcgtc gcgctcctaa aagaagacta caaggagttg
     4141 ccagagcact accaaccagt gttcacgacc ttcaagaaat accaaacaga aatcaaacga
     4201 gcgttgcgcg ttccctattc caacggccct atagaatgtt tgaataacca tatcaaagta
     4261 ctaaaacgaa ttgcctatgg ctatagaaac tttcaaaact accgagaacg aatcttttta
     4321 tatcgaggaa aatattttaa gaaaactaag aatactaccc aactgactaa agccagaaca
     4381 acaacacggc tagacaagat agctgtctag ccgtgtgagt atctcgatta ttctattgaa
     4441 tttcttcacc aacactcatt gacgaagagc caaaataagt aatctaaccg actgttaact
     4501 aaaccattgc aggtcccgtt aaagatactt gtgcctgttg tcaccgcttc tttttcttgt
     4561 ccacaagcgc ttaacacact taataaagcc cctgctatta ttaataataa tatctttttc
     4621 ttattaaaaa cctcctcatc tatttccaga ttagtaaatg tagtaatctg tgctttcttt
     4681 tttctcaata ctaataacta acttatgggg taaacaaata ctcgtttgac cgggttttga
     4741 gatccatcca gttctaaccg cgatttgatc aggactatta tcttctttaa ctcgaattct
     4801 tccatcttta atctcaacaa tattatattg tcccttcgca ggatgataat tcacgagttt
     4861 atgattgatc ttatccaaat cgaagcgatc catttccttg ccatcaattc gaacgatggc
     4921 atatttgata gcatcttcag ttgtttcatt ctccttttct atagagaata caaataaggg
     4981 aataaaagag gtaataatca aaatgccaat aattatgaca tcgcctatct tgacaccagc
     5041 ttttcttaaa aatttcatta acgatatctg gctaaacata ttagactttt tccatggaaa
     5101 tggtgaaatt tttcggaaat tatctgcatt aagagaatca gttaaacaac cctcaagttg
     5161 ttccttaata cattgttgat ccatcttcat accaataaaa actagtttat taatgcgttc
     5221 accaaacaac ggatgccagg cttccttcaa ttcgggattt ttttgtataa tcatttgaca
     5281 ctcaatttta ggtaaactag ctacccaata atttaatgat tcaatacttt tatagctacc
     5341 cgatgtttca aagatcgtcg aaaaatcact atgttgggca aaccaaagaa acccttttgc
     5401 tcttgtaata ttgccaggaa aatttttatc cgtaagatgg gcaaattttt gtgcgtcaag
     5461 gagtaaccga tttcgataga taaaacttga gataccatat tcttctgttt caggaatatg
     5521 attttgatag ccaagctcta actctttgaa ccagcccact gaataggaag tctcatctat
     5581 attaaaaaga tttgtattta gaattttcga taagtctact tcacctttaa ttgtcctaat
     5641 tattttggca ttggactgta acttagcaat tagaccgtta attttgtaaa tcgtcttggt
     5701 tgacactaag tcactattat ttaaaagtaa tatgttacaa cactcgaatt gatcaattaa
     5761 caagccacga atatcctgtt cttcttcaac tacattacct tcagcttttc tttcctgaat
     5821 cttttcaccc gtttcgaaat tatcccaaaa acgttttaca tccactacta taataatggc
     5881 accaatctct aatcgttggg tcaaatcaat gtctaaaggg tttttagcta atataattgc
     5941 ttgaataatt ggaattggtt tgctgattcc tgaagcttca ataacaattt gattcaagtc
     6001 agaaaattgc actaattgat ctagttcaac aatcaaatct tcgcgtaatg tacaacaaat
     6061 gcatccattc ggcatcgaaa caagtttttc tccagttctt ttaaaacctt tcttgtcgac
     6121 taatacccca tcaacattta cttcccctat gtcatttaca atgacagcaa tttcctttcc
     6181 gtgatcaccg tacagaatat gatttagaag tatcgttttt cctgaaccaa gatagccagt
     6241 taagattgta ataggtattt ttttcatagg gaacctcttt ctataccttg aatttacact
     6301 ttaagtgcaa cacataaaaa tgagtcataa tcgatatcca actagtataa gtttgtcgag
     6361 aacactccta gaaggaaaat aattatgagc cagtatcgtc atcttactat actcgaacga
     6421 gaaagaatct ttctgcttca cgaagaagga ttttctatta gtataattgg caacgacatt
     6481 cagcatagcc cgtttactat tttacatgaa ctgagaagaa acaagaaaaa aactattcac
     6541 cttccaaagc ggaaaaaaat tatgcttatc gaagaaaaaa atgcggacgt tatcacattc
     6601 taaatgatcc gtgagtttgg tcaattgttc gtcatttatt tgtcgatttt cagtggtcgc
     6661 cagaggaaat ctcgaatcgt ttgaagcatg aacatatgga cttttcaatt agttttatca
     6721 cgatctaacg tgcaatttgc aatgatcttt tcgatacaga acccctctca cacggcaata
     6781 aaggcctgat ccgttcattg caccatcgag gaaaaacaag acatacaaaa aatcatgtcg
     6841 agtctcgtgg aaagatttgc cttactcatt cgatccatgg ccgtccaaaa tccgcagatg
     6901 atagaagtga ttttggtcat tggaaagccg atattgtagc tggcaaaact ggtggtactt
     6961 gtttagtgac tttgacagac agaaaatcat gcttcctttt agcaggaaag aaggtcccca
     7021 gaaagaaagc cgcttatgtg agcgagaaaa tgattgaact tttaagcagt attccaaatg
     7081 aggcggtcaa aacgatcact ccagatagag gaaaagaatt ctccaatcat ttcgcagtta
     7141 cagaagcatt gaataatatg cccttttatt ttccagatcc tcatgccctt ggcaacaatg
     7201 aacaaattaa aatacgaata gactcattcg agaatacttg ccaaaatcga aagagatagc
     7261 tacggtagat aactcaacga taaatcagat gattgaaaaa ctgaataaca gacctagaaa
     7321 gtgtttagat tggagaacac cttatgaagt cttctttgat aaagtgttgc gcttgatttg
     7381 acaattcaag acataataaa aagcagatca aatccaaata agggaaaaat gatctactct
     7441 ggtattatca attaattggc caagctatta tgccgttttg ctaaacgtct acttcttcca
     7501 gtattgacct tgataaaaca acaatcagga tcccgtttta atactctatg aactgtgtca
     7561 atactaacat gtaaagttgc agcaatatca gctaatgtac tcccatttaa tctcatttgc
     7621 tttgcaaatc gataacgccg ataagcatca atattcttgg aatccataga caataatact
     7681 tttcttacca tgtatttcct ccaaaaattg aattttaatg agccatcatt tcttgagcaa
     7741 tttcatgttt agacaatgaa gctggataga aagtaggcca attatgcaat tcattataga
     7801 gtttttcttg actttctcca ccaaagaaaa tatggaaatg ctctgcctta cttggtgcaa
     7861 ttccatgatc actaaattga atatatttaa aacgaccagc acctgcatca tcagtttcaa
     7921 aattaaaacg aacaccacgg tttccttttt cataattcaa aattttgtat ccaacatatt
     7981 tgtatgtgta ttgatgatgt tcaccgttga ctacaaaatc aatggtgttg tctttaatgt
     8041 tgatagtatc aatatctgtc ttatagccag tagtataata atctttgtac tcggcagctg
     8101 tcatgtcttt attgattttt gctttgtaat cgaaaacttc atccaaaatt ccatctttta
     8161 acaacggata aacagattgc cattcgcctg tataatcact caattcgcga tccttcacat
     8221 cggcatcttt aaagtaccca ttagcaactg tcttttcatc cttcgcttct ttttctggaa
     8281 ctacctcttc accagcaacc atagttgttt tttctaacgc ttttagattg tcttccatta
     8341 ctgaaacata atcttcacca ttatccattt gttcttttgt aagactttca agaggattca
     8401 gtacttccaa ttttatccca gcttcgttgg ccaaagtttt tgcaatttta tcattagcat
     8461 tcttttcaaa gtaaatataa ttgatcttat tttttttaac atactctttt aattcagcta
     8521 atcgaccaga agatggctct tcttcaggac ttagtccagc aataggaact tgtttcaatc
     8581 cataatccaa agctaaatat ccaaaggctg cgtgttgcgt cacaaaactt ttttgtttcg
     8641 cttctttaag actagtggta tagtcagcat ccaaccgttt cagtttagtc aaatactttt
     8701 cagcatttgt ctcaaatact tttgcttttt tcggatacaa tttaactaac tgatccttga
     8761 tatttgaaac ttccttaatt gccattttgg gtgaaaccca cgtatgagga tctagttcat
     8821 gatggtgatc ttcttctccg tgatcatgat cttcttcttc actacctggc aataaaatca
     8881 tgtcttttgt tccttctact acattaggcc cagctttctt ccaactttct ttagcttttg
     8941 gtacccatga ttccatgttt tcgttatgat atacaaaaac atcagcatca tgagcttttg
     9001 ccatatcctt agctgagggc tcatagtcat gaggttctga tcccgctgga accattaaat
     9061 ccacgttcgc ttcatcgccg acgatgtttt tggtgaaatc atacattgga tagaatgttg
     9121 ttacaatttc taattttcca tctttatcat tcgatacttt tgcatcatta gtgctggagc
     9181 aagctcccaa taatcctaga gctgctatcc caataagtcc tacactgatt ttcttcattc
     9241 tttttccttc cttaattatg ctaatttctt cattttattt cgtttatgtt ctttgataat
     9301 ttttaatgcc ctttttctag ttttaatatt cgggctttta agtcgtcgat atgcactaga
     9361 tatatccgtt ttctccatta gaaattaccc ccaatcacta cttatcatta tttgctttcc
     9421 gccagtaatt tatcaaaact ctgtttgatc ctttcttcat ccaacatttt tccgattaga
     9481 ataatagtgg tttggtcttt ttgtcgagtg gtgtattgaa aattaacctg ttcgtttacc
     9541 tcttgcatgg caactataaa atcctgctct tgtaaagcaa tcaatccttt aaaacgatac
     9601 aggctccctt ggttggttaa aatcagccag tcaatccatt ggagtaaaaa atcttttttt
     9661 atgtcttgat ctgaagttaa gagaattgat ttaaactcat gtacttgatg gtgttgatga
     9721 tagtatttgc cattatagtg attttctgat gaatcacttt caaaaactaa gggatgatta
     9781 aattttttca aattataaaa atcctttttt tgaatcgttt cactatgtgt gaacattcga
     9841 atatcggata aagggttaat acttttgatt tctctctgta atttttttag tgcagataaa
     9901 ttcaagtttt gttttctaga cacaaaaatg cgatctgcca tgacaagttg cttaagggct
     9961 tgtggttctc tttcaataag ttcaaaactg tcactatcaa taacagtcaa taaactatcg
    10021 atatatactc ttcctcttag ttgaggcgct gttaaaagtg tttgaatgat tggttgggga
    10081 tctgctatac ctgtagtttc aatgatgatt tgtgaaattg gttgttgatg ttcttctatt
    10141 gtttccagta aagaaatcaa tattgctaat aaatcactgc gaagactgca acacatacat
    10201 ccattattta gttgtaacac ccgttcctcg ctatgaacta ataatttgtg atcaatccca
    10261 acttcaccaa actcattttc aattataata atttcttccc tggggtaggg tgagacttgc
    10321 aaggcttgat tgattagcgt tgtttttcca gcccctaaaa acccagaaac gattgtaact
    10381 ggtatgccca ttttgtcacc tttttaccac ttagctattt cacttcttta aaaattgccc
    10441 gtctgcgcaa ttttggcgaa tactttttta attctaaccg ttcagggtta ttccgtttat
    10501 ttttgctggt gagatacaga cgttctccag tttcgacaca ttccaaaata atattttgac
    10561 gcataaatct tcctccttca atacttatcg atcttcaaga tatgcttgaa tttgttgtgc
    10621 atcttcaaaa gttaactcgc cagattccaa ttgtgaaact aaattttctt tcatatcaac
    10681 aggtatctcc caataaccat cgatacattg aaataactcc tcgtcatact cttcaaaaat
    10741 tggatagatt cttaaaaaat catcaaatga taagccttgg tcctcatagt aatctttgac
    10801 taatccattt tcaattgcct gttgggtcgg taaacccgtt tcagtaataa ttcctctctc
    10861 taccatcgaa cgataaaaag tgcatttatc tagcgattgc tgggtcgttt caagataata
    10921 ctttaatcct tcttcaacta aaggtgggta aataatttcc attttgattc cctcctaaaa
    10981 gttatatatt aaactatttt gaagctcctt taattacttt ctttccatta tagtaccctt
    11041 ttaaagatac atgatggcta cgtctataat caccattcgc ttcgtcaaat gaaatttctg
    11101 gttttactac agtttgatga gttcttctta accgtttctt cgccttagat gtttttcttg
    11161 ctggtactgc catgatattt cctcctttta ccaacttgct ttttttactc caggaatcaa
    11221 cccttgatgg gcaagttctc taaacttaat acgggacata ccgaactttc gcatataccc
    11281 tcttggacga ccatccgtct gatcacgaag cctcagacga ttcggatttg aatctcttgg
    11341 caatttagcg agagcggtgc gatctcctgc ggtttttaat tcctgacgtt tatctgcata
    11401 cttttcaatc atcgccattt gtttctttgc tttagcaatt ttcgactttt ttgccatata
    11461 cctttatact ccttttattt tgatttagac acctcaaatc gtaatcgtta cgttttgaca
    11521 ctgatacttt accaacaaga gttgctcttg tcaacaataa ataacatgaa ataaaactca
    11581 tatgaataga taactatttg aaaacgaatt tatcggtaca tagagataat caaatcattt
    11641 aaaagaatat gcagtttagg ctctgaaaaa taagaattca cttttattag tccaatcaaa
    11701 cacaaatacc gttttaagta gcttttcctc tacttaaaac ggcaatatga aagaaactat
    11761 aactttttat tcaatctttt atgtttaact ggtttatcgc caatttttta aaactttgat
    11821 tattccttat attataagaa tagacattaa gtgaactaat tcaatcatac tgattctttc
    11881 gtgtattcaa aattagatgc tgtttaataa aattattctt tttgaaaaag aattataact
    11941 atatcccaaa aattgtaggt taatttaaag cctatttcat catcgtgatt gagcttcttt
    12001 ttcatagacg aatttctcag atagtttagt tttctttatg agatttttgt atatttctga
    12061 ccttcgatac aactcattat gagtaccttg atcaactagt tttccttgat ccatcactac
    12121 aattttattt accttttcaa tagacttcaa gcgatgcgat ataattagta ctgtcttatc
    12181 ttgtattaaa cgatttaaac tttcctgaat acgtttttca ttttccgcat ctaaactggc
    12241 agtaatttca tctaaaatta aaattggcgc atttttcaaa aaagcccgtg ctatggatag
    12301 gcgttgtcgc tctcctccag aaagtgaact tccgttttct ccgaccaatg tatgataacc
    12361 gtcaggtagt ttttcaataa agtcttcgca gttagctaaa cgagctgctt ttttcacttc
    12421 ctcatctgac gcttgactat ttccaatacg tatattttcc aaaatacttg tattaaacaa
    12481 agttacctct tgaaaaacaa tagcgatttt gctaaacaaa gaagctggag atacacgttt
    12541 aatatcatac ccatcaatta aaatacagcc ttcatcataa tcatacagtc tagacactaa
    12601 tttcaagata ctagttttcc cggaaccact agcacctact aacgcagtca cttctccttg
    12661 tttagccgta aaagagatat gatctaaaat tggggtattg ttatcatatg agaaagagac
    12721 atctcgcaac tcaatgtcaa aagatttcag aggactatct gatccctctt ggatactggt
    12781 ttccttcata gctctaattc gctgtatttt aggagctaaa taaaatattt caagcactgc
    12841 ttctttcata gaatcgaagg aatcctttat ttttattgcg gctagtaagt aaccaacgac
    12901 gtagagtata gtcacttcac ccgttaacag taagtgaaca cctactagaa tgactactgc
    12961 taaactaaca tatgagaaaa tagaggataa ggccatgact gaaaaagtac ttaattctac
    13021 ctttaaatga atcctttcac tctcttccat ttttttgaaa agtctgtctt gaactttttt
    13081 agatagatta aagctattaa tctcttgctg caattctata gtttcttgaa attcttccga
    13141 gttttctctc aaagtatcgt aatatttagt attggctttc gtttgggatt tctttgataa
    13201 caagattaag acaaaactaa ataacgttgg caaaataaca gctaatccca ttttgacatt
    13261 accaaccaaa agcatcactg aaataaaagg gaaaaacaga gccataccgc cggctttagg
    13321 tattgcatga ctcatcgcat gctcaatacc ttcaacgtca gacatgatag tttgagataa
    13381 atctgataaa ttatgttttg aaaaatagga taatggtaaa tttgacaaat cgtctgcaat
    13441 ttgcactctt aaatgcgcac tttctttata agtactatta tataagtttt catactccct
    13501 atctaacaac caatacatga aaagcaaagt aacaaacgat acggcaaaat aaagccaacg
    13561 gggctttgta ttttctaaaa ctaattcgtc tatcagcatc attataatga atgctggtac
    13621 catattaatg cagtatacaa aaaaactaga aatagaagct ttagttaaag cttctgcgcc
    13681 ctgatcactt aaagcaaatt tgtttttata aaaacttttc attgtcaagc ctccaatcat
    13741 ttgcattctc ataattagtg accaattgtt tatacacttg atgtttagcc attaattcat
    13801 tatgatttcc acgttctact attttccctt ctgacaagac aagaatttca tctacagatt
    13861 taatgctgga taatcgatga gctatcataa taactgtttt ttctttcatc agatgttgaa
    13921 aagccttttg tagttcatac tcattatctg gatcaataga tgcactggct tcatccataa
    13981 taacaatctt tgcatctttt aaaattgctc tggcaatagc tatacgttgt ttttctcctc
    14041 ctgacagata aactccttta ctaccaatta aggtatgctc tctttcggga aatttttcta
    14101 aaatcgattc gcaaccggct aatcttagcg cgtcaaatac tttacttgct ggcgcttgag
    14161 gatttgctat agaaacgtta tcgtaaatac tctgattgaa tagtttcgta tcttgaaaga
    14221 caaaagcaat tgtgttaata attgtgtctt ttgaatagtg atttaaaggc ttaccaccaa
    14281 ttttaatctg tcccttatcc acattgtaga aacctgaaat tagtttagct atcgtactct
    14341 ttccgcttcc tgattttcct actaatgcat aaattctttt ttgttctaaa actaagttga
    14401 aattttctaa aacacactct tctttgtatg aaaagctgac attttcaaat gcaatgtcac
    14461 aatttttaat ctgtgtctcg ttcccatatt ttagttggtc ttgcttcatt tctaaataaa
    14521 gggagtctag tgtttcgact gcatatcttg cttcaaacaa gtgcatactt acatacatta
    14581 ttctcatgaa agaaacaaaa ataattccac ttaaaaaaaa caacatcaac aagtcaacag
    14641 ctaatatctt gggagtggta agagaagtta taaaaaaggt tataggaact atcaaaatgc
    14701 aaactatgcc aaaaaatagc cattgaaaaa gaacaaaagg tgttttccca ctcaaagaat
    14761 acttatatgc aaacttagca taatcgttaa ttgctttatt caaggcttta aatgatgtta
    14821 ctttagcacc aaatatcttt ataacttgaa ttccgcggat atattctacc gtttcagagc
    14881 ttaacacatc taacgattct tgatattttt gaataaaatt tgtattctct gtcattttct
    14941 ttaacaagaa tacaccaatt actaacatgg cgattagaac caatccaatt ttaaagttaa
    15001 tgaaaaagcc taaggcaact gataaaacag gtgttactat ggcttgagca ctatctggaa
    15061 tcaagtgagc aattgccata tgtgttttag ccgcgttgtc atcaattgtc tttcgaatat
    15121 atcccgaaga atttaaatca aaaaaacgaa aacttgcttc tgttaaaccg ctaattccct
    15181 tttttctcaa attagtctct aagcgaaacc caaggatatg agaaaataag ccagaaaaaa
    15241 tataaaataa agctcctaaa gttaaccaag caacagtttg aaccgcataa ctcttagcta
    15301 aatattcatc tcctacaata attagagact gaagaaattt gtaaatactg taatatccat
    15361 agactgttaa tacgacagaa aaatcagaaa ataaagtggc taaccatccg tagtatttca
    15421 ttttagggac ataactaaat aattttttgt atactttcat tttttcctcc cccgcattca
    15481 atttcttctc ttattcgttt acaactgtta atgctttccg taatagcgta aattagagat
    15541 gtacaaacag ataaaaggta aactacgttc tattttttgt atttttttaa gacttttctt
    15601 ccaatcaata caccaatcat agataaactt gctacaacta acactgaaat gattccccat
    15661 atacctaccg catagtggat cattgcatcc attgttgcag cagattgtcc tttatctatc
    15721 caatcttgac gaaaacgatc tgtaaagaac catataggaa tccactgtcc ggcagcactg
    15781 cctaattgca ttagagccca agacgcaact tgaggaattg ctcgatcata tccaaataca
    15841 gatagaataa tatcagctaa gatcgccata ctaatcgaac tgataaacca aggtaagtac
    15901 gccccgccca ttaacgtaaa aaataacaat aaaacaattg tgtaaatagt aaaaattcct
    15961 tttctagggt agttatagct aatataaaca aatatgattc cagataataa tccaaaaatc
    16021 ccgggggata tgctgtgacc aaacgcccca ccaatactac taaccattat tgaaaaaaag
    16081 taaattacta gggaaataac tgtagctaaa ccaataaaaa tataatcttt tgttttcata
    16141 tatattctcc tcaattctat ttcgttatgt cattaaaaat ctgttctatc aaagttgaat
    16201 cttctactct aagttttata tcttttttta ttccaccatt ttttaaataa ataattctat
    16261 tgcatgtttt ataaagaaat tccggatcat gagtagctat aactactgca cccttttctt
    16321 ttaagtcttt aataaggtca gcaatccttt ccatattaat ataatccaac ccacttgtag
    16381 gttcatcaaa tagaaataaa ttagtttttg acaatgaagc tatagaaacc aataatcttt
    16441 gtttttctcc accggataaa tcaaacggta attgatcttt cattttataa agttccattt
    16501 tttttaaaat tttttcttgc tgatctttac taactatttc attccccagg gctaactcgc
    16561 tcctcactga ttctgtgaaa aattggtaat ccatttcttg cattactaaa aacggcgatg
    16621 acaaattttt tttattttcg attatctttc ctttggtagg gcgaataatc ttcatgagta
    16681 ttcttagtaa ggttgttttc cccacaccgt ttttccctac caaaccaata acatctccaa
    16741 ctttgacatc aaaatttatg tcttttagaa tattttcata agtaatttct tcaactttta
    16801 atacatctgc acttaccttt tcgatatagg gaacttcaat cgaactatta aaaatgtcaa
    16861 atttccttaa tgcgttattg ttttcagttt ttaacaactg aatagttgta gtttttacag
    16921 ttctattttt aacaaataga acttgatcaa ttaattcttt caaatagtaa aaacgatgtt
    16981 cagctataac aatagtaaat cctttatttt ttaaatcaca aagtaagtca gcaagtttct
    17041 tagtcgcttt gaagtccaaa tttgaagacg gttcatccaa tataattaat ttagagttta
    17101 gcgataaact acatccaata gaaattttct gccgttcacc acttgatagc gaaaaaatgt
    17161 ttttatctaa tatatttgaa agatctaata attcagctaa ttcattgatt cttttatcca
    17221 tatgctcttt tgtaaatcca aagttttcca tcgaaaatac taactcactc gttgtatttg
    17281 ttgtaaagaa ttgtcctcta ggatcttgac ttacgtagcc aatatttttt gatatacttt
    17341 cttgtgttaa ggattgtagc gagttatttt caaataaaat ttccccaacc aattttccgt
    17401 cataaagtct tggaataagt ccattcatta actttaatag tgtggatttc ccactcccag
    17461 aagaaccagt aatcaatgta agactgcctt tttttattga aaaattaagg tcaacaagcg
    17521 cttgttcctt aacatcctta tatgaaaaag aaacattgtt aaattcaaac aattctttca
    17581 cctcaaatca aaatacttaa gaaaaaaata gtaacggaaa acaggatgat atagtctaat
    17641 aagctcatgt ttgttttata gtaagaactt cttttcacag gagattctat cccctttgtt
    17701 attgcattag cggtcatttc ttcagcaatc atagttgcac gtataagaac gggaactaac
    17761 agaaattcca aatattgcag aggctgaaaa aaagacaagc gaatgtttct catttttaaa
    17821 gattctttaa tcattcttat ttcagaacga taagtcggaa agaatctgat cactactgta
    17881 atacttaaca ttattttttt cggtaaatgt attttttcta aagaggataa taattcattg
    17941 ctagtataga cactaaccaa caaccatgag atcattacga ccggcaacat tcgaaataca
    18001 atatataagg atgtcgcaaa aaatatagta aaaaactcta tcttgatagc atcaataatt
    18061 ttcattacta aaaacagaac tgaataaatc aagatgaaat aaatacatgt ctttatttta
    18121 cgaaacatca atactaaaac tgtagcaata atgaaacacc ccacttgaaa tatatttccc
    18181 tttcctaaaa aaataatgac cggaaaaaaa atatttaaag taatcaaggt taacggattg
    18241 atttttgaca ctctttcacc tccaaaaaat aagatcgcac tgttatctta agctgataaa
    18301 aatgcaccgt tattcagata acagtgcgat cttatcaaaa agcataactg agaacaattc
    18361 tcaatgcaag ctttttttaa ttaactcagt aattcaatcc acccaggaac agaaaattga
    18421 tacaatcttc tggttaatag catagtcttt tcttttgaat agctatgctt caatatatca
    18481 tagaatgtag cgtagaatga gtaaatgtag aagtggattt cttcttcatt aaagactaaa
    18541 ttttgattga tcattccgat agtctttaac ttatctagac aacagactgt ctttttcgtc
    18601 acaaatgatg taattttttc aacaatatct tgatatttgg ttccagctga ttggaataaa
    18661 atcaaatcga atatacgttt attctcaaaa atataattaa taaatggatc taattcattg
    18721 aagttctctc tccaactttt ctctatatct atattttcta agtttaagag gtatttggta
    18781 aactcttcat tatacatatt aataagcgca ttaatatgcg gctgaataat ttcttcaaat
    18841 aacgcttcct tagaagtaaa atgtttataa aaagcacccg tagttacgcc tgcggtcagg
    18901 cacagttgcc ttatcttagt ttgctgaaat ccttcttttt caaaatggct tagtccactt
    18961 tctattaact tttggtgagt tataatataa tctctggttt ctatgggtac ttcctcctaa
    19021 taagatgaat taactttatt atcttacaca ggacttgaag tttcaatcgt taacgtttat
    19081 tactgaactc attccttaga gctaaactaa tgagaaagag cagaataact gatacaaaaa
    19141 gcaatcctac aagaattaat agactcatct aaatcattca ccttttctaa aataatccga
    19201 gaaagattta aaaaaattat atccagctat taggataagt cctatcataa tcactccaat
    19261 agccattttc ttatcctccc taaaaataaa gtcttttact taaaaccttt tttgtaatcg
    19321 tcaataaatt ttttcccttt atcagttaat tgaaatccta tatctaaata gtcctcatat
    19381 ctaagtttag ccagcatctc acttacagat gctggactaa cacttagaac ttttgctaaa
    19441 tcattatttt ttaatttctt ttttcttttt gataattcct gaattgctag taaataaatt
    19501 agtatagtag tcgttttaat ttgtaccata cctaccctcc aaattatttc gaaaggcctt
    19561 cagcaatttt atccaggttc catttcatca tcgcatagta actatcacca tcttgtcctt
    19621 tttctgcaat tgaatcagta aaaatcgttg aatagatagg aatattggta tcttttgata
    19681 ctgttttcat tggtctatca tccacactgc tttctacgaa taaggaggga acttttgttg
    19741 tgcgtaattt ttcaactaag tgttttattt gatctggtgt tccttcttct tcagtgttga
    19801 tttcccaaat gtaagcagaa ggcacattat acgctttcga gaaatattta aagcatcctt
    19861 cacttgtaac aatcattttt ttatcattcg gaattgaagc aaatttagat ttagcttctt
    19921 tgtctagaga atccaatttt tcaatatact tatctagatt ttctttatag aattttttat
    19981 tatcaggatc tttttccgct aactgttttt caatattttt agcgtaaata ataccgtttt
    20041 ctaaatttaa ccaagcatga ggatcttcct tccctttctc actctgaccc tctaagtaaa
    20101 taacatctat gccatcactt gctgcaaaat agtctttgtt ttcctctttg ttcgcatttt
    20161 taactaattt tgtaaaccaa gcatttcctc cagtttccaa gttaacaccg ttataaaaaa
    20221 tcaaatctgc ttttgaagtt ttttgaacat cttcaggcaa aggttcatat tcgtggggat
    20281 ctttcccaat aggtacgata ctgtgtaaat caattttatc ttttgctata ttttcggtaa
    20341 tatctgctaa aatcgaatta gtaactacta cttttaattt ttcgttcgaa gccactttat
    20401 ctttgtcttt actatttatt gaacatgccc cgaatataaa aagagcaatc aaaatcccca
    20461 gacttcccag tactgctttc cattttctca tcataacgat ctctccttct ttcttaaaaa
    20521 tttttgtttt ggtgagatta gaaaactaat tacaaataag aatgccgctg ttaaaacaat
    20581 acttgatcct gctgctatgt taaaactata accaataaac aatccaagca atgatgaact
    20641 tgctccgact gttgcagaaa taaatatcat agttttcaag ctatttgcat ataaatatgc
    20701 tgtagctgct ggtgtaatta acattgcaac aattaatata gttcccacac tttgcatagc
    20761 tgttactgct actaaagtta atagaaccat caatagataa tgataaaaac tgacattcat
    20821 ccctattgct tttgccatta atggatcaaa agaagtgatt aataattctt taaaaaatag
    20881 aactactata accaacacta aaaccgaaac gccaattgta atccacttat caatatcttg
    20941 tacagctaaa atatttccaa ataaaatatg aaataaatcc gttgagctat ttgcaactcc
    21001 tataaggata actcctagtg ctaaaaaaga actgaaagta ataccaattg ctgtatctcc
    21061 ttttattaca ctattgcttt ttataaaagt aataatgata gaagctaata gaccaaatac
    21121 aatcgcacca ataaaaaaat taatacctaa aatataagaa attgctactc ctggcaaaac
    21181 agcatgagaa atagcatcac ccataagaga cattcctctt aaaataataa aacaacctac
    21241 tgttccagaa acaatcccta taactacaga tgtaattaga gcattctgta aaaagtgaaa
    21301 gtcatacaga ccattaataa aattttgaag catattattc cccctctcca ataaatatag
    21361 tatctccata ggcttttttt aaattttctt cattaaatac agattctaca cttccgtgag
    21421 caattagatt tcgattcaaa agaataatat tatcaaaata cttctttacc ttgcttaaat
    21481 catgatgcac aattagcact gtttttccct gatgtttcaa tttttttaac gtatccataa
    21541 ttattcgttc actaactaag tctatcccta caaatggttc atctaaaaat atgaaatccg
    21601 cattttgagc aagacatctt gctaaaagta cacgttgaaa ttgtcctcca gataattctc
    21661 ctatttgatg attagaatat tttcccatat cgaccttttc caaagccttt gaaactcttt
    21721 gccattctgc atttttaatt ctttgaaaaa ctttcattcc ggcatatgtt cccatagata
    21781 cacattcttt tacttttatt ggaaaagtaa aatcaatatc agctttttgc tctacatatg
    21841 caatcttcac cagtttttta ttgatatctt cattattaat ggagacctct ccctgatgag
    21901 ggataatatt taacattgct ttaagcaatg tggattttcc agcaccattt ggaccaataa
    21961 tacctgttaa agcaccttct tgtattttta aagaaatctc gttcaatgct aaaaaatcgt
    22021 tataacaaac attaagcttt ttcacttcta acataacttt ctccttctaa atgataatga
    22081 ttatcacgat catatggtat acaaaaatta tattttagtc aaccctaaat tttatagttt
    22141 agattttttt ctgttgctga agattagaat gacaaaacta tttgaaacta cgcgtatagt
    22201 aagtagcttt caaaatatat aaaaaaggag cgttctcaaa tgagaacatg ctcctaaaac
    22261 tactttattg gcgtatggaa aaattatact tgaagtggat agcgggttga ataagttgat
    22321 aagcatcaaa acatttataa aaattattca agactatgtc tgttccatat acaaatatga
    22381 aaatcagtaa actccattta acttttttcg tagtgtgtct ttttatacat gtttatcgtt
    22441 attaatagtg aataggaaaa aaactatttt tgatcattga caattaaata caatttttga
    22501 ataacgatcc ctgctattcg agctagaaac tcaagtacgc catgacctga ttagcgacaa
    22561 atacttagag atttcttttt gttctgggaa aacaaaatgc catgacaata gcagcaaata
    22621 atgatacttc cgtaaggctc gccgtaaact ggggagaggt gaaattccta tgtgcttacc
    22681 caaagcaatt caaaaatttc ataactacta ttttaggaga tgattttata gaatccagag
    22741 tctacctgaa taaaaaacaa acctgtgcat ttctaggaat cgataataat actctagata
    22801 agtggattcg tatatataat ttcccagtaa taagagttgg tggtgtagtt cgctttgacg
    22861 tagaagatat taaagacttt atgaatacat ttaaaataac ttgaaatttt cttctcgccg
    22921 catatactaa aattagtgaa atatactgcc ttactttttt taaggagtga ggattttgcc
    22981 tacaaagctt tcaaatggga aatataaaac taatctgaga tatccaaaaa ggtttaaaga
    23041 aataacagga attgcatcag aaaagtatca aaaaacattt ccaaataggc aattggcgat
    23101 taaagccgaa aatgatatga agaagaaaat agaaaaagtt ttgagagagg agaatgcaaa
    23161 ctcattagaa ttaaaaggaa aaataacgtt taaaaaattt tacgaatcta aatggcttcc
    23221 tagatatgaa ttaggtcaaa caattagatc aaacaggcct cctagtgata taaccattag
    23281 taatacaaaa gatatatttc ggttgcatat tttacctatg tttggtgaat acgcaatgaa
    23341 ttatctaaat atcaatactg agataatatc agatgaatta accaaaaaat cgaaagaata
    23401 tgcaaatata aaaatcataa aaggatatgt tcgttccatg ttcgatattg cagaaatact
    23461 aaattatatc gaatttaatc gaactactaa aattattcaa agtatcactg cacctaaaaa
    23521 aaatgcttta gaagaaaaaa gaatacaaga aggtaagcaa gcactatcat caaaagaact
    23581 tactaattgg atagaagcag taaatgatga ttttaataat catttactta cttttcatga
    23641 ttacacactt tttatgatta ccctgtatct tggtgataga aaaagtgaga cttacgcttt
    23701 gcaatggaaa tatattgatt ttgaaaaaca aacggtccgt cttaaacata ctttagataa
    23761 atatcaaaga aaaaagttta caaaaggtcg aaaagatacc gtcattcaag taccagaagt
    23821 tgtaatgaca ttgctaagtg aatggaaatc ggtacaagct gatcaattgt tgaaattaaa
    23881 aattaagcaa acgttagatc agtatctctt tacttatact aaaccatctg gagaagtaaa
    23941 ttgtcctgtt catgccgatt acctaaacta tcgaatcaat tcaattaaaa gaaggcatcc
    24001 tgacttagtt catttatctc cacacaaact ccgtcatact tatgcaacta tagctagaca
    24061 aggtggagca gatatgaatc aaatttcaaa tgctttaaca cactcagata tttctacaac
    24121 aaagatatat gtgaacacac cagatatagt tgataaggct gtttttgaag cttttcagag
    24181 aggattgaat aagtgtgatt gatatgtgtt cttaaatgtg ttcttaaaaa caaaagaagc
    24241 actttccaaa taattgaaaa gtgccagaaa cgttgatata taaaggatat taacgttttg
    24301 agaattgtga agctttacgt gctttcttaa gacctggttt tttacgttcg accatacgtg
    24361 cgtcacgagt aagtaagcca gcacgtttaa gagctaaacg gaagtcagga tcaacttcta
    24421 gcaatgcacg agcgatacca tgacggatag ctcctgattg tccagcgtat cctccgccgt
    24481 ttacgttaac aaatacgtca tatgcgcctt ttgtttcagt aacagcgaaa ggttgattga
    24541 ttacttcacg caagtcagca tgtggaatgt attcttcaac atctttttta tttacagtaa
    24601 ttttgccagt tcctggtact agacgtacgc gagcaactgc gtttttacga cggcctgtgc
    24661 cgatatattg aacttgtgcc aatgaaattc cctcctatta gattaagttt gtgatgtcta
    24721 aaacttctgg ttgttgtgct gcatgtggat gttctgctcc accgtatacg ttcaattttg
    24781 taaattgttt gcggcctaaa gtgtttttag gaagcatacc ttttacagaa gtttcgatca
    24841 aacgacgaga atttttagca cgcaattcgc cagcagtgat tgatttcaat cctcctgggt
    24901 agttgctgtg acggtaataa attttgtcag tcgctttttt acctgttaat ttcactttgt
    24961 ctgcattgat gacgatgacg aaatcgccag tatccaaatg aggtgtgaaa gttggtttat
    25021 ttttaccacg tagtacagat gcaacaactg ttgaaagacg tcccaatgga acatcagttg
    25081 cgtctactac ataccattta cgttctactt cgcctggttt ggccatatat gttgtacgca
    25141 cgttattttc ctccaattta agttctgatg tttgacatac acttcgagtt tccggggctc
    25201 tttgtggggc aaacaatacc atttaacata ttacccgcta atctagtcaa tgtcaacgtt
    25261 tttctgcttg attgaaaaat ttatatgaaa ctttacttct tttctttctt ttatataaaa
    25321 gggtcgtttc ctgtcaaaat gaaaaacaaa aagaggctgt gacaaaagtc ttgtcacaac
    25381 cccttatttt gaataaacgg tgttctcctg ccaactcctc ggtcacaagt cacaatatcc
    25441 ataaaacata agaagctgtt ttttaaaatt gtttcttgtg actcggagct gaacggcagg
    25501 cttacaacct cttggtaaac ggtgttcaat cagctgaccc tcggtattag ctcaaaaaac
    25561 ggcaaaatat gaggaactat tttgacgttt gtttctctaa tactcaggtc aaaacgctga
    25621 tttcacaacc tctttttcgg tcaagttcaa caacagtttt tacgcgtcga tctctggcgc
    25681 tttgcccaaa tgagcttgga tcatccagat acgtttttct gtggctgttt tgaattcgat
    25741 aaagatatct tgtgttggat cgtcgccttc ttctccagaa acttcgattc ctttttggta
    25801 aagatctgct agataacgat agcctgcaac aagtgtttcc aaacgttctg gaatagtacg
    25861 atcccagcgg ccaatttcat cagggatttt tgtgttatct gcaaattcac gcaatgtaga
    25921 ataaggtgaa ccgtctaatg tgatcaagcg ttcggatact tcatctaact gagcgttcaa
    25981 atcatccatg aactcatcca tcattgggtg caatgtaagg aaacctggtc ctctcatgta
    26041 ccaatgtgtt tggtgaacaa caacagacat ttggcttaga tctgcaacta attgatttaa
    26101 tacttctttg gtttgttgga atttcatctt tcttgcctcc taacattttc ttacacttaa
    26161 aataatagta gactttcaat gaaaagtaca acaaaatcat ttacctgaga acgattttca
    26221 gttcgctttt ttatccgtaa agccaatcat ttttcagaat cagctaattc ttctcgcagt
    26281 tgagcaaatt gctgataagt ctgtgctaaa tgcttttgtg tcgaaacaaa taatggatag
    26341 attttctgat attttttatg atcagtttct tgtactccaa cttgctcttt caattctatc
    26401 aattcctgtg cttcactgat actttggatc tttccgatgc ttctccagcc taaaatcaca
    26461 gctcctaatg cggatgcttc tgtgacagta gggaaaacaa gcgggtaacc cagtacatca
    26521 gccatcatct gacgaaaaat cggagattga gcaaacccgc ctgtagcacg gatctctgtg
    26581 agctgatttt cctggcaaac tccttttaaa atccgataaa ggttgagaca gatcccttct
    26641 agaatcgcct tcatcatttc tttttctgta tgttgccgct gtaaaccgat aaaactgcca
    26701 aacgcatctg cgtcccaaag cggtgctcgc tcaccaagta aatagggatg aaaaatcaga
    26761 ccattggcac ccgctggcac aaaagcgata gccgaaagca gtgcatcata tggattttct
    26821 cctttttctt tagcagattg aacgacttcc tgtaaaaatg tatgccctgc ccaatcaaag
    26881 atgccagcac cattgctagt cgctcctccc actacccaat gtttctgatc cagaacataa
    26941 caaaacgtct ccatttctgg atggaactga ggctgagtag taataaaacg aagtgctccg
    27001 ctcgttccta cggtcaaagc ggcgatcgta tcaccaaaag cacctaaccc tagattagaa
    27061 agcggcccgt ctgcccctcc caaaacaaat gatatatcat ttggcaaacc tagttctgct
    27121 gctgtttttg atggtagacc tgttacttga taggtggaag gaaagacttg cggcaattgc
    27181 tctattcgaa tgttcaagta gtcaagcact tcttctgccc attggaattc atggatatca
    27241 aaatatccag ttcctgaagc tgttccgtag tcgctgatca gttcgccaaa caatctataa
    27301 aagatatagt ctttgatacc gacaaaataa gcagtttttt tgaataattc aggttggctg
    27361 ttttgcagcc acttgatttt gttcaatggt gtcattggat gaatcggcgt cccagtctgc
    27421 cgataaaatt ctttgccaag cacggtatat ttcagttttt ctgcttcgtc cgctgctcgg
    27481 ttatctgccc aagtgatcat tcgagataac ggtgttttct cttcatccaa caatatcagg
    27541 ccatgcatcg cagaggagaa ggagacaaat tgaatgattg tgtctgaagg caactgttta
    27601 attacttctt ttataacggt gcagacacct tgaaagatca attcctgatc ttgttctgcc
    27661 atcccttgtg tttcttggat caaagggtag cgaaaataag cggatgctgc ttcttgggct
    27721 tcatctgtga aagcaactgc tttggtttgt gtggttccga tatctaatcc gattgaaacg
    27781 ttcatttttt cacctcaaat tttatgtatg tacaaaaatt tagtttaagc ttgcgtatct
    27841 tggttttgaa aagggggaga tggcgtgtta ctttatttta tcattggttg ctgtatcgga
    27901 tcatttttat gtttaaccgc ccagcggatt ccgttaggtc actctattat ttatcctaga
    27961 tctcattgtg tcaaatgctg tcgttcgctt tcttggtatg aattgattcc gattctctcg
    28021 atcatcgtcc aacgatttcg ctgccgctat tgcaggtgtc ggttgccctt ctactatttg
    28081 ttggcagaag ccttatgtgg tggtcttttt gcctggttct ttactttttc ttccgcaaga
    28141 aatttttcga cgttcatatg gatgctttcg gctttgctat tttcgttgat ggatttattt
    28201 tacttcatgg tccattctca cacgctattc tgttcttggg caattttatg gattttttgg
    28261 ttgcaggccg gcgtcttcca atggcaaagt gtgctgttaa cgtttatcgt aggcggtgtg
    28321 tgccttcgct atggtcaatc ctatctcgga gctggcgata ctctgttgat gctttcttgg
    28381 agtggtggct tgtctctaga agagttgctt cagatcttgt ttcttgctag tctgtttgga
    28441 atatccgttt tttctgttta ctttatctgt cataaaaaaa agttggaaaa gctgcctttc
    28501 attccttttt tgagcagtgc gttgctgatt gtccttcatc ttaggtattg aaaaaaggtt
    28561 gtgacaaacg acttgtcaca acctctgata tatagtgttc tcttaccaaa tccttgtgac
    28621 ttggagctag gcgacaggtt cacaacctct ccactaaatg gtgttcaatc agctgaccct
    28681 cagtattagc tcaaaatgct ggttttacaa cctctgatat acggtgttcc ataagtagct
    28741 ttttcggctt cttatttctt gacgccccaa tgtcgacgaa ggaaacctgc acgtccagaa
    28801 ccttctcgat aaagattgta atggagcttg tttttcttgt aataatcctg atggtaatct
    28861 tctgcaggat aaaattcgct tcttggttcg atttttgtca cgattggctt atcgaatcgc
    28921 ccgctgtctt gcaatgcttg ttttgaacgc tctgcaatat ttcgttcttc ttcatcatta
    28981 tagtagatca ctggacgata agaatcaccg cgatcagcga actgtcctaa tgcgtcagtc
    29041 ggatcggttt gctgccaata gatttccacc aactgatcat aagaaataac ttctggatca
    29101 tattcgatct ctactgcttc tgtatgccct gttgtgcctg ttgttacttg ttcataagtt
    29161 ggatttggta catgcccgcc agtataaccg gatgtcacag aaatgatccc tggctgctct
    29221 tcaaatggtt tgaccataca ccaaaagcat ccgcctgcga aaactgcttt ttttgtcata
    29281 taaaatcccc cttttttctc atcatacctt gatttccaaa aggaggataa cgttttgctt
    29341 gtgacagaaa aaacggaaac tattatatac gtgatacggc ttctgataaa tgccaaaacg
    29401 aacgtacttg atcaaaaacg gttaaatcag gaatcacata ttcagcagaa ggaagattta
    29461 tgttttcacc tattcccaat acatgcatgt taccagccaa agctgcttga caaccagctt
    29521 ctgaatcttc aatgaccaag catgcatttg gcggtacatt caattgctgt gctcctttga
    29581 gaaaaacttc tggatcaggt tttgcttttg atacttgcgt gccgtcaata aggacatcaa
    29641 aataacttgt caaattcgtt ttttctaaaa tgaggcgtgc atttttgctt gctgatccca
    29701 atccgatctt gatgtttgtt tttttcaagt actcaagaac agctattgca ccaggcaaaa
    29761 cggatgtttc atccattttt tgaatcgctt gaagatatag attgtttttt tgctcagcaa
    29821 aggctgattt ctctttttct gagaatttct gttccatttt tccaaatgac agcaatcgct
    29881 ctagtgactc ggttctggat attcctttca gttgctcgtt ttctttctca gtgaatggaa
    29941 tggacagctg gttagctaaa accagccacg cttcgtaatg ataacgagct gtgtctacaa
    30001 gaacgccatc taaatcgaat agtgctgctt tgattttcat cgattacctc cttgaaaatg
    30061 aacgacttga agtaaagatg cgatgttttt agctgtgcga tgaagattat cagtggcttg
    30121 ctgtaaagct tcttgtaaag gcacagctgc aggaaggatc ggaaaaacgg ccgaaatgcc
    30181 aacatctgct gctttttcgc ttcctttacc aacacttccg caaatagcta tcacaggaac
    30241 gccctctggt actcttctag caatcccaac tggcgctttt ccttttagac tttgtccatc
    30301 tagacgtcct tcgcctacga ttacgaggtc tgcttgctgt acccgtttat cgaactccag
    30361 taaatccaat acgtagtcga tgccagagac tattttccct gaagcaaatg ctaacagtcc
    30421 tgcacccatt ccaccaccag cactactgcc cgatgcctcg attacttgag gggcaaatct
    30481 catataaaaa tcatgcatgg cttggtcagc cactgctaat tcattttctt tcaagccttt
    30541 ttgtggtccg aaaacaaaag aagcgccttc ttttccgcat aaaagattag taacatcagt
    30601 aatgacagtg attttggctt taatcagctc aataggcacg ttcgttttat caactgtagc
    30661 aattttacct agattttctc ccagtgcttc tactttttga ttatcttgat cgtaaaaagc
    30721 ataacctaga ccttctgcca tgccgatgcc gccatcgttg gtactacttc cgccaacgcc
    30781 gatgatgatg tgtcgaacac cttgttgcaa caattgtcgt atcagttctc ctactcctcg
    30841 cgtggataac ctaagtggct gttgttggtt tagtgggaca tctttcaatc cgacgatttc
    30901 tgccatttca aaaatcgcag tttgaccgtc tgaagcgtac tggatttctt tgtttttgcc
    30961 aaatgcatta gtaacgactg ctgtttgccg cttcaacctt aaactgtctg ctaatgatga
    31021 aaccgttcct tctcctccat cgcctatagg tagcagatca tattcagcct gaacaaaaac
    31081 ttcttgaaaa cctgattgaa tggcttgtgc tgcctctaag gctgtcagac tttctttgaa
    31141 agaatctggc gcaatcagaa tacgcattat tttcccctcc gttccaagat cagttctttt
    31201 tccagctggt attggtctcc attgacaaaa ataggtaatg tttctttcgt ctcttttttt
    31261 attactattt gtttttttgt caaaacaaat agcaacctgt gatttttcca aataaaagga
    31321 aaagaaattt tttcccatgc tgaaggaagt cttggagaaa tagaaagagt tccattcgtt
    31381 actgtaatac ctgaaaaacc aaatataact gctagccata gtgctcctaa tgaagcagca
    31441 tgaattccgt catctgatga atgcggatct ggtcctaaat caatcaggca cgcttcttgg
    31501 aataaatgat acgcccattc catttcttgg atacggcaag cctctatggc gtgaatcgct
    31561 ttactcaacg atgagtcgtg gattgttttg ttttcatagt aatgcaaatt cttagaaacg
    31621 attggttgag aaaaatactc aggtaataag tataacagca tgacaagatc tgcttgcttg
    31681 ctgacttgga gttcatttac ttcgctacgg gcataatcaa gtaaaataga ctggctgcca
    31741 ggacgttctt tgtaagtggt caaatcaata actggcttac tgagatacgt gtcatcttgc
    31801 ggaatcagct gttctttgtt aggcactggc aaatataact tatctaaaaa attttgacat
    31861 tctttcaaaa aaagcggatc gccagcttga tatttaacag ctaaggccac attataatgc
    31921 gccagatagt tcgtatatgc attattgtcg atatattctg tgtattcatc tggaccaatg
    31981 actctgtgta tctctaaatg atcatcgact tttacagctc tgctcagcca aaaagctgct
    32041 gtttcatgaa tgagcgtttt tccctttgtt tctaaaaacg attgatcctc tgttgcttgg
    32101 acatactctt gaacggcata agcaaggtct gcactgatat gatgttctgc ggcagctgaa
    32161 gcaacttctt gtcttgttcc ggttttgata ttcaatgcag caaatttggg tgtctcttcc
    32221 tgaccagtgt gtgcgctttc ccatgggaaa agtgcacctt gatagtgata atctcttgct
    32281 ttttgccgtg cgccttctaa tcgatcataa cggtacagca gcaaattctt tgctacttca
    32341 ggaaactgat ataaaaagaa aggcaggata aaaatttccg tatcccagaa aacatgccct
    32401 ttataacctt cgccagttag tcccttcgcc cctacactaa cacttggatc attgcgggga
    32461 gtcataatct gtaaatggta agcagcgaag tccatcgcta actgatcgaa agaagaatcg
    32521 ccttggatcg ttatccgatg ctgatgccaa aaatctgtcc aataagacat cgactgctct
    32581 aaaatttctg tataactaac gcttttctgg gcttgggcaa tacttttctt aaacgggtct
    32641 gtttgctgaa gagaggtaga gagcacgatg atcttctcca gcgtaaagga cgtatttttt
    32701 ctgatctttt ctgaaaagga agcggtgatc cggcgatttt ttgcttggaa tacacctgct
    32761 ttattgaatt tagctgcaat cccaatatca attttacttt ctgttgtctg gtaggatgca
    32821 ctgatcaaat cgtcaccaaa tactcgcagt tctttttcaa ccaactgctg tgtaccaaaa
    32881 ttggtttgct gtccatcgat acccgttttc acatctactt ggcagtcttc ggtcaacggc
    32941 ttgatgacca ctttcagggc tgcctgatgg agattatttt gatcagcaac acgacaagta
    33001 atgacttcca ctttttttcc ttgagcagtt tcaatgagcg catagcgttt aagctctccc
    33061 atttctaaat ctagtgcccg ctcgtatgca agaactttca tcgtctcaag agaaaaatgt
    33121 tcaccgtcga tttttatttc ccatctgatg acatctggga gattcactaa ctcggctgat
    33181 tctgctccta aaggtcggtt atatacacca gctgcaaaca ttccccttac ttgattccga
    33241 tagtcttcct cctggcttcc tctgatacca aaaaatccat ttccaatggt catctgactc
    33301 gcatacttat tgatatactc taaatcaaac tgtttttctt ctactttcat aaggtaataa
    33361 cttctcctgt ttctgccgaa cgatataaat tttccaccag attctggatg acatatcctt
    33421 gccagccatc tgcaatcatc tgagtctggt caccgagcgc ccgattcaca aaatgagcca
    33481 tacttagttc atgtgggtca ttaactggcg tggtcttttg taaggaaacc agctttccat
    33541 ctacatcttc gaatagttcg cctggataca gattagcacc tgcctgatcg ccacaaaaag
    33601 ccacattcag tttgtcttct ctgatattca aagcaaacga agtattcagt tggatgatct
    33661 tgccgttttc taattccagt gtgccaaaaa ttgcatcttc tactgtgaat ttgcttggat
    33721 cccatttccc gaatttccct gaattttttt tcgtaccaat tttttggaag ctgtacgccc
    33781 gaacgctttt tactttagga aatccagtaa tatacatcgc tgtatcaagc atgtgaatgc
    33841 cataatcgat caaaggcccg cctccttgaa gttctttgtc gataaacgtt ccccagcctg
    33901 gaacaccaga ccgacgaagc gcattcgctt ctacgtaata aatatccccg agaacatcaa
    33961 gatgattctt gatcattgtt gcttcgtcag aaaaacgatg ctggaatcca taagccaaaa
    34021 tctgcccgtt tttatcggct gtctctgcca tctttcttgc ttgatcagct gtcatagctg
    34081 gtggtttctc gcacatcact gaagcattag cttcgagggc agccaataca tgttcgaagt
    34141 gaaagcgatt gggtgtacag acactcacga tatcgggaga aatctcattc agcatttgtg
    34201 taactgatgt atacgcatga gaaaatcctg tacgtcggca aaagtcttct gctcgctggc
    34261 tgactggatc aaccacagcg gccaattcta agacatctga tcttttttga taataagcag
    34321 catgtacttt ttctgctact tgtccagcgc ctatgattgc tactttcttc atttatttct
    34381 ccctcctttg cttatttact tattgttatt ctttctctat tctttctcta aatcatttaa
    34441 atgacgcgct gtttccagac agtttttcaa gtattgcaat gattcctgat aaattttcac
    34501 ttcattttct cctcgcaaac gacattcata taccatataa ccttcatact cattttgaag
    34561 tagcgtttga aaatggcgag taaaatcaat tgcgccagat cctggttggt agcgatgatt
    34621 atctgctaaa tggatatgac ccacatactc tttttgcgta gtcaatgctt ttgaaatatc
    34681 atcttcttca atattcatat gataaaaatc agcgatgatc tgcacatgtt tcaattgatt
    34741 agagtcaatg taatgacgcg catccgctaa caaattgatc atatggtctt ggtatcggtt
    34801 caaaggctcc aaataaataa ccgtacctgt ttcttcggct actttatcta aataacgaag
    34861 tgattcgctg actgctttat agtctccttc tttgcttcgg ggtgaaacca tcggcggtaa
    34921 tcgataagtg aacattcccc aagctgctgg gataacgatt cctttgcctc caacctcgct
    34981 tagtgcacgc aaaatctcag caatttgacg tacaccatta agacgccgtt cttcgataaa
    35041 gtcaccgatc cacccatcgt agccgttaca agctgtcact actgggatcc ctgtttcttt
    35101 gattgcctgt ttgactgtgt cgatattttc tattaacaac ttaccgtcga tttcgtattc
    35161 ttcaaatcca cagtctttga taaatctaaa tttttctaaa atgtctcttg ggaaaaatgc
    35221 ttgatcttgc gtaccgaatt tcattgttct cctcctcgga cttgaacgcc cattttgata
    35281 ctttcttctg ggtgctggtc tacataacgc atgtaagctt ctgcgctttc tgcaaatggc
    35341 acaactggat caatgatttc ttcacaatcc aagtaaccgt tcatcaataa ttcccaacat
    35401 gtgtcctcga ttcgtttacg gttccatctt gggtaatctg ggtttggttc actagatgct
    35461 cgagcaaaga cgatttttgc attattgaaa tgtgcttcgc gaccaagatt aaacccagct
    35521 ggaaaaggtt tagcaaaggc aacataagaa atgatcccgc catagccgat ccctcttaaa
    35581 gaagcttgta atgcggcagc actgccactc gtttcaataa ctgaatctac tccacgttta
    35641 tctgtcaatt cctttagacg aaaaccgaca tctgctttca taggatctag cgtgtaatcg
    35701 gcaccgtatt tttctgctaa ttctctacgc tgcgctatgg gatcgatccc aacgatggta
    35761 gtagcacctg cttttttagc taattgaatc gcaatttgcc cgatagcgcc taaaccgaag
    35821 attgctacag catcacctgc tcgaacatgt gcttcccgga taccacctaa agcgaattga
    35881 gcaggatcgt aacatactgc atttttccat tgatccaacc gatcaagttt acgtagttta
    35941 taattatcaa caccgtttgt aatcagcgtt tcacgaatgg gtccataagt gcagactaac
    36001 tctccttttt gatactctgt caccaaactg cccgtttctt cgatcgtacc gacaatcata
    36061 tttcctaatt gaaattcgcc aaataccaca ccgcgttggc ttccttcttc tcttggcaag
    36121 aataggcgcc attcttctga aaattcttca tcgataaatg gacttaatcc tctaaagtcg
    36181 acaatttctg ttcctggttt tggagtagcg aaaattactc ggatacgtac ttcgttcttt
    36241 tcgatctcac ggtcttcgta atctttgaat ccggctattc ttggttctaa tgcaactaat
    36301 tttttcatct tttctttcct ctttcttttc tttttatcct tttacgccgc cttcgactaa
    36361 atcaccttta ataaatcgtt cagataacgc atacataatg atgactggta aagcggtcac
    36421 caatgaagcg gccatcattc gtccccaaat gtagtctggt gtactgaata atgtgttcaa
    36481 accgattggt aaagtaaatt tttcggaggt cgacaggaaa atcgaagcaa ataaataatc
    36541 attccacgaa accataaagc aataaacgaa gacagaaatg attccagaaa tagccaatgg
    36601 tataatgatc cgaataatga tctggatccg gctaagacca tcgatcattg ctgcttcttc
    36661 aatatcagtc ggaatcgtgt caaaataact ttttagcatg aatatcgcag taggaagtgt
    36721 ttgaacgacc atcgtgataa tcagtgctgt attggtatca tacaaaccta gaccggaaat
    36781 gattttaaat aatggaacaa cgatcaaaat accggaaaac atataaacgg tgtaaaagct
    36841 agcattgatt ttcgagcgag ctttgaagcg tagttttgac aaagcgtatg ccccgctgat
    36901 cccaatcact actgcagtta cggaggctat caaggagatc actaaactat ttttgaaata
    36961 catgatgaat ggaaaaatct cagcattgaa aatatcctga taatgttcaa aagtccattc
    37021 tttcggaaaa atagtttgtg tcgttgcaat tgcttcttgt gaatccttga atgatgtcat
    37081 cagcatgatc aaaaatggaa acaaattgac agctaatagc aacaaaatcg tcgcgtaaaa
    37141 taagattttc ctgctctttt tatttttcat ttcaagtcca ccttctttcg tgagagcaag
    37201 acgaccgctg caataatgat gaacaataga atcgatatag ctgctgcttt tccaagatca
    37261 ttgaacgcaa aggctgtctg atacaaataa acgcctaaga tattgacttt attcgtcagt
    37321 agatagacat ctgtaaacat atagaacatc cagatagatc gtaaaacaat cacagttgct
    37381 agtactggtt tgattgccgg cagtgtcacg atcttgaact tctgccaagc atttgcaccg
    37441 tccatttcag ctgcttcata aagcgttttg tcgactgttt gcaaaatagc caaaaatgaa
    37501 ataaacgcat acggatagta tctccagata gcaaacaaaa cgaccataaa gaagctagca
    37561 actggctggt cgaaccacag cggtgcttcg ttgaaaagct gcaacctatc tactaacaga
    37621 tcattgacga ttccataact attattgaac atatatttcc aagcaaaaat caaagaaata
    37681 gatggcgtaa cataacttaa taaaatcagt gaacgcaccg ttttcctaaa tctgaacttg
    37741 cggttaagca aaatagctac ggctaatcct aaagctgtac tgcctgctac aactaagaat
    37801 gtgtaagcaa ctgttaaacc taaagaacga taaaattcac tatcacttaa aatttcaaga
    37861 taattgctta atccgataaa aacggcgtct gagttaggat tcagcggcat atcgaaaaaa
    37921 ctgatctgaa tattggaaag cattggaatc agcactaaaa cagctaataa aagcatgctt
    37981 ggtgctaaaa gtcccatggc taattttaag tcagaatgtt tccttggacg attcattgaa
    38041 acctccccct gataatctgc caatagctat ctactttttt cgaacaccat tggcagaact
    38101 tcttgttatt tcgtattttt ttgtgcgtca gctaaagctt gatcgacatc ttcgtttccg
    38161 acagttactt ggttcactgc ttttccgatc acacctgagc ttgtgatatc tcccattttc
    38221 gtgaaattct tttccccgac tagtccaaag acttgtactt catcaaaagc actagcaatc
    38281 tcagatggca gctcgccaaa agacttgatg acttcatttt ctttgtaacc atccagttcg
    38341 actacttgtt tattcactgg ttgagcacca ccaggagaca tcaagaccca cttttccatg
    38401 tttttcggtt gagataagaa agctgtgaat gcttcagcag cctctttttg tttctcgtct
    38461 agaccagaag aaatcgtcaa tccagatact gtgccataga cagcttgatc tttttgtgtt
    38521 gggatagcaa aaccgatatt ttctgagttc cccgcttcat aaacagaagg caaaatgtaa
    38581 gttgaataga ttgccattgg tgctgttcca ttcatgaaag catctttgat ttctgtcaca
    38641 tcattagagc ctggcatcgt gtattgggat aagttttgat aaaacgacaa tgcttctctc
    38701 atcttttccg tatcgatcgt tacctcgcct tcatcatcca aaacatttgc tccatttgac
    38761 aaagcaaatt gagagaacgc ttgctcactc attgttcctt cagcagtagg catagcaatt
    38821 ccatattgtt tattctcttt atctgtgaaa tgttgagcaa tttttaaaat atcatcccaa
    38881 ttttctggtt ctgaaaaacc agcttctgat aatttttctt tgtcatacca aataccttga
    38941 acccagccgc taattggtgc agcaatatag ctttttccat cttctgaacg aacaaggttt
    39001 ttggctccgt cataataatt atcttctcca gcttcctcga taacgttttg gactgccgtc
    39061 tgatcaatca gttcatcttt atccatcact ttagcaaaat cctgactgac ttccattact
    39121 tctggtaatt taccggaacg agctaacgta acgatttttg tattgaacgc tgattcttct
    39181 accggcactt gcttgatttt gatgtctgga ttttcttttt caaaatcagc aaccagttca
    39241 ttgatcacac ttaatcgttc ctgttcgaca gaagagtgca tgaattgaat cgttgtctgt
    39301 tgtgattcgt tagagctttg actttcacca caagcagtaa gaagaaatcc agtagctagc
    39361 agacaggtag taacaataat ttttttcatt tttttccacc tcttatttta ttattttcag
    39421 ccacatatat tcatacggct ggaatatcaa ctttcgttct tgactgcaat ggataatttg
    39481 tccagaaaac aggtctaggt aatctccttt tggtaaaaga taacctgctg attgattgga
    39541 aaaattatgg ataactaaga ctttctcttc cttcgcttcg cgaataaaac tgataaaaga
    39601 atctgctgag tccagtaagt aaatcaaact attcggatgg aaggcttttt ctttttttcg
    39661 aatagatagc atctgggtca attcaccata tactgctgtt cttaatggat ctgtctgcaa
    39721 ctctttctca atatctgcta acaaaaattt ttgccgattg atttttcgat tctctcctgt
    39781 tttttctacg cctttgtaat catttcgact tcccagcaca ctttgaatat aaattgccgg
    39841 cacgcctggt aacgttacca aaaatgaatg agcagctaaa aagcgtttgc ttctccattc
    39901 cgtcgtatct gttggagaac ttaacgcatc tagatacgta gcgtttatct catatggact
    39961 ggtcgttcca tctgggtttt tcttgtagtt tactcgggta ccctctttct tcagctgttc
    40021 cactaattca aggatcgttt tttccggcag aatacctcgt accggattca atccgatacc
    40081 gtcatgggag gctaaaaaat taaaaaaagt tgtttttttc gatgcgaaat cgatggtttt
    40141 taaccattct ttcaacttac ttgtattacc cgaacgaatc gcttgaaggg tcaaaggtgg
    40201 tagcgaaaac tgatagacca tctgtgcttc attctcgcca ttcccaaaat aactgatatt
    40261 atctttgtgt ggcacatttg tctcagtgat caataccgtt cctggagctg cttcatcagc
    40321 gattgcacgg aataattgga tgattttatg cgtttctggc aggtgtatac aagaagttcc
    40381 tagttctttc cataaaaatc ccacagcgtc caagcgaata aatgaagcgc ctttttctaa
    40441 gtaaaacaaa agaatatcga tcattttcaa taaaacttct ggatttttaa aattcaagtc
    40501 tacttgatct tcgctaaaag tcgtccatac gtgtttttct ttcccgtttt tgtcaatgaa
    40561 cgttgtaagt aacgggctgg tccttggtct agtcacgctg cttgtatctg tatccagtgg
    40621 caaatcaata aaaaaatctt tgtacgtatc attcaagttt aaatattcct gaaaccaagt
    40681 actttcggca gacatatgat tgcagacaaa gtcgaacatt aaccgtgttt cgcttctcat
    40741 ttcttctata tcttcccatg tgcccaaacg gtcgttgatt gcctgataat ttacaacgga
    40801 gaaaccatca tcagatgtat atgggaaaaa tggcaagaaa tgtacaactc taaatgtatc
    40861 tgccaaatac ttttgataaa atttcttaaa tgtacgcaaa gttggttgct gctcttcaaa
    40921 aaattgatcc ccataagtaa tcaagaaaat atcttcttcg tcccaatgca gtttgcctgc
    40981 ctggcctttc ttctgctgat aaacactgac tttttgttca atcatagagg cggttttctc
    41041 agacaaatct gagtcgcgat aaatcgcttg taaaagtttt gtatacatcg gattcccctt
    41101 tcttttttgg gagcgttccc aacgatttga tcatattatg gaaaacgctt actgtcaata
    41161 gcattttttt aaataatttt gatatacaca aaaatacaaa taagaaagct tatgtatcaa
    41221 taattaatag cttcttaaaa aaatatggtc tctcatgatc atgcaagcta ttcctaaatt
    41281 ttcaaaatca tagacaaaaa agaatgtcta ttgtactatg gaattattct aaaacgctcc
    41341 caaaaaggag gtgcatataa aattgaaacc tactatttat gacattgcga aaaaagctaa
    41401 tgtctcaaaa tcaactgtct ccagagtatt aaataaccag ccaaatatct ctgataaagc
    41461 aaaagcaagt gtacttcaag caatcaaaga attgaattat gaaccgagca aaattgcaag
    41521 aggactgtca ggaaatggtt ttgacgcgat tctagcatta tctcatcgta cttctcatac
    41581 gacctatggc aatccttttt tttcagatgt tattcaatcc atttctgccg tttctgaaca
    41641 aaataacttc gacttgattc tacaaacggc aaaaacacca gaagaagagc tagaaaaatg
    41701 cgcgaaaaag atccaagaaa aaatgatccg aggaattatt attttaagct ctacgatgga
    41761 tgaaacactt ctttttgaat tggatcaata caatattcct attgtggtaa tcggaaaagt
    41821 cggaaacgac tacacgaaca tctactcagt ggacacggat aatttccagg atagttacga
    41881 tttggtggaa acactgatca agaatggaca ccgtcatatc ggctgtctcc atgctccgac
    41941 agaagtttat gtatccaatg atcgtctcaa tggttaccgt caatgcttat ttgatcacca
    42001 cctagatatc cgtaatgaat ggattataga cggcggcttt cgcttagaag atagcatggc
    42061 agcaatgaat gatttaatga agctacgaga aagaccaact gcgatttttt ctaccgatgc
    42121 attaaaatca ttgagtattt acaaagtggc agaacaatct ggaaagcaga tacctgatga
    42181 tctttcgatc gcaggattca gtgatccctt attgtcctcc ctattttcgc cacagttgac
    42241 tcggatagac attccgacaa atcagttagg aatcaaagcc acagaacttt tattccaact
    42301 aatccaccac caataccctg aagaaaaaag aatcattctt tcaaccgaga ttactctcac
    42361 agattcgatc caacaacaag aaatgtagaa cagaattata aaagaacaga aacactgagg
    42421 ataagtcagt tactctgttc ttttttcaat cactcatccc tcgttacccc ctcccggtat
    42481 tttagcgaat ttttcttatt ttccatctgt tttagatagc tgtggataac tataatgttt
    42541 gtgttaaact attttttcca cagggaagaa aaaactattt ttaaccacgt tgtgtataag
    42601 tttttatagt tcgttttttt aaacacattt acccttattt caatccatgt tatttgggga
    42661 tacttatctc taaaacataa atagaataac agacatgtct actggttttg ttttattcga
    42721 ggaattattc aataatagct agcaaaatat taaaaataac cgctctatct tcccatcaat
    42781 ttattttgca ttcaaaaaat gatctatctt tacttttgtt gattgacttc tcttggaaga
    42841 tgatcgttcc gataccttaa ttggatacga accgatgttg ttaagatcct ttcccacttt
    42901 tcttctagtt agacaaatta ttttagacaa accaaaaaag aggttgtgac aataatttgt
    42961 cacaacctct tttttaaaat atctattttg tttgattgtt cattgcgtct tctgcagcca
    43021 tttgcgcttc aatatctgaa atactgtaga cattttcgct tgctacaccg acttcttttg
    43081 gttccatgtc acgataacgt tgcataccag taccagctgg gatgatctta cctataataa
    43141 cattttcttt caaaccaaga agaggatctt tcttaccgcg gatcgcagca tccgtcaaga
    43201 cacgagttgt ttcttggaat gatgcagcag ataagaaact atttgtttct aatgatgctt
    43261 ttgtgatacc tagtaagaca ggtcgagaag ttgcaggaac gcctcctgag actagcgtat
    43321 tgtagttttg atctttaaag tctgcgatgt ctaataatgt acctggtaag atatctgtat
    43381 cacctggatc cattacacga actttacgca gcatttgacg aaccattact tcgatatgct
    43441 tgtcgccgat ttctacccct tgcatacggt aaacacgttg tacttcacga agcaagtagt
    43501 tttcaacaga taatacatcg cgaacttgca acaattgttt tggatcgatt gatccttctg
    43561 tcaatggtgc accacggtgg atcatatcgc cttctgctac tttcatacgt gctgtataag
    43621 gaacagtata cgtacgtgta tctgtttttc ctttgattgt tacttctttg gtacgtgttg
    43681 caggatcttc tgagatatcg atgacatccc ctgttacttc tgtgatcact gcttgccctt
    43741 tcggattacg tgcttcaaag atttcttgga cacgaggaag accttgagtg atatcgtctc
    43801 cggcaacccc acctgtatgg aatgtacgca tcgtcaactg agtaccaggt tcaccgattg
    43861 attgagcggc gatcgtacca actgcttctc cgacttcaac gtcagagcca gttgcaaggt
    43921 tgcgtccgta acaatgtttg cagacaccat gttttgtatt acatgtgaag acagaacgga
    43981 ttgtcactgt ttcgacacct gcatcaacga tttgttttgc gatgtcttcg gaaatcaatt
    44041 ggtttcctgc aatgatcaat tcatttgttt caggatgacg tacttcttta cgggtgtaac
    44101 gtcccactaa acgatcttct aatgattcga tgatttcatt tccctcgcgg atggcttgga
    44161 tttcaagacc tcggtcagta ccgcaatctt cttcacggat gattacatct tgggccacgt
    44221 caaccagacg acgagtcaag taacctgaat cggcagtctt caaggctgta tcggtcatcc
    44281 ctttacgagc cccgtgagtt gagataaaca tttccaagac ggatagtcct tcacggaagt
    44341 tcgaaatgat tggcaattcc atgattcgac cattaggagc ggccatcaaa ccacgcattc
    44401 cggcaagctg tgtaaagttg gaaatgttac cacgagctcc agaatcagac atcatgaaga
    44461 ttggattttt cgcttccaaa ccttccatca gtttttgttg gatgctgtct tttgcagcat
    44521 tccaaacagc aatgacacgt tcataacgtt cgtcatctgt gatcagacca cgacggaatt
    44581 gttttgtaat agtttcaact tgtttatggg cattttcaat gatttcttgt ttttcattca
    44641 gtacactgat gtcagcgatc cctactgtga taccggcatg tgtcgaatgt ttgtacccta
    44701 agtctttcat acggtcaagc atcttagaag tttctgttac tttgaatcgt ttgaagactt
    44761 ctgcgatgat gtttcctaag tttttcttct tgaacggtaa tactaattct tgctctttga
    44821 tatgtgcagg aatatcagta ccagcttcaa caaagtattt gtccggtgtt tggacggtca
    44881 agttgaagtc tgttggttca ttcagataag ggaattcagg aggcatgatc tcgttgaaga
    44941 tgatcttacc aactgttgtg atcatcgtac gttctttttg ccattcagta aatggttttt
    45001 cacctaatga gttagggttc acaccgatac gtgaatgtaa atgaacatat ccgttgcgcc
    45061 atgcgataac ggcttcgttt tgatctctga agaccattcc ttcgccttcg cgtccttctt
    45121 cttccattgt caagtagtag ttacctagaa ccatatcttg ggaaggagta acaactggtt
    45181 taccatcttt agggttcaag atgttttgag cagctaacat caacatacgt gcttctgctt
    45241 gtgcttcttc attcaatgga acgtggacag ccatttggtc tccatcgaaa tcggcattat
    45301 aagcttcaca tacaagtgga tgcaaacgga ttgcgcgtcc ttgtactaaa actggttcga
    45361 atgcttggat accaagtcgg tgaagcgtag gtgcccggtt cagcaatact gggtgttcct
    45421 tgattacgtc ttctaaaaca tcccatactt cgtcttcttg acgttcgatt ttacgtttcg
    45481 catttttgat gtttgaagct agttcgcgtt gaacaagctc acgcatcacg aatggtttga
    45541 ataattcaat ggccatttct tttggaagtc cacattggta catcttcaag aaaggtccaa
    45601 caacgataac ggaacgacct gagtagtcga cacgtttacc tagcaagttt tgacggaaac
    45661 gaccttgttt ccctttcaac atatgagaaa gagatttcaa tgggcggtta cctggtccag
    45721 taactggacg tccgcgacga ccgttatcga tcaatgcatc tactgcttct tgcagcatac
    45781 gtttttcatt ttgaacgatg attccaggtg cattcaagtc taacaaacgt ttcaaacggt
    45841 tattacggtt gattacacga cggtaaagat cattcaagtc acttgttgca aaacgtccac
    45901 cttctaattg aaccattggg cgtaaatctg gtggaataac agggataacg tccataacca
    45961 tccagcttgg ttgatttcct gaagcgcgga atgcttctaa aatatccaaa cggcggattg
    46021 cacgtgtacg tttttgtcct tgtgcagatt tcaattcttc tttcaattcg gctgcttctg
    46081 catctagatc aacattatca agtaattgtt taatcgcttc tgcacccata gcagcttgga
    46141 attcttgtcc atattgttca cgtttttcgc gatattcgcg ttctgtcaac aattgttttt
    46201 tctctaaatt cgtatttcct ggttcgatga ctacatatga agcaaaataa atgatttctt
    46261 ccaaagcgcg tgggctcatg tctaatacaa gacccatacg tgaaggaatc cctttaaagt
    46321 accagatatg tgaaacagga gctgctaatt caatatgtcc catgcgttca cggcgaactt
    46381 tcgaacgagt aacttccact ccgcatcgat cacaaacgat tcctttataa cggatacgtt
    46441 tgtattttcc gcaggcacat tcccagtctt ttgtaggacc aaaaatccgc tcacagaaca
    46501 acccttcgcg ttcaggtttt aaggtacgat agttaatcgt ctcaggtttt tttacttcac
    46561 cgtaagacca gcttctgatt ttttcgggag aagccaaacc tatttgcata ctttcgaatt
    46621 tatttacatc gatcaaaagg ggttccctcc atttcattta atggcaaacc gcaagacggc
    46681 tgatcttcga ccgccttgca gctcatagac cggattagtc taaattatct tctgcggttt
    46741 caaagttttg gatgacatcg tctttttcat cttccacttg ttcagcagct ttcttttcta
    46801 attctttggc agtttgctgt tcggcaaatt ttgtcaaagc atcaacagtg atcaaatcgt
    46861 cgtcttcatc gtccatgtcg cgaagttcga tctctgtttc ttcgatatcc aagacacgca
    46921 tgtccagacc tagtgattgc aattctttca ccaatacgcg gaatgattcc ggtacacctg
    46981 gttttggaat tggttcaccc ttgacgattg cttcgtatgt tttcacacgt ccgactacgt
    47041 catctgattt gtatgtcaag atttcttgta aagtataagc cgcaccgtaa gcttccagtg
    47101 cccatacttc catttcacca aaacgttgtc caccaaattg agctttacct cccaatggtt
    47161 gttgtgtaac caatgagtaa ggtccgattg aacgtgcatg caatttgtca tcgaccatgt
    47221 gagcaagttt gatcatgtac atcacaccga cagacacacg tccatcaaat ggttcacctg
    47281 tacgtccgtc gtacagaaca gttttcgcat cgctggccat accggcttca cgaactgttt
    47341 cccatacgtc ttcatcactt gcaccatcaa atactggcgt tgctacgtgg atacctaact
    47401 gacgtgcagc catacccaag tgtaattcca atacttgccc gatgttcata cgtgaaggca
    47461 cccctaaagg attcagcatg atatcgattg gtgttccatc aggtaggaat ggcatatctt
    47521 cttccggcat aatacgggat acaacccctt tatttccgtg acgaccggcc attttatccc
    47581 cttcatggat tttacgtttt tgaacgatat aaacacgaac taacatgttt acgcctggtg
    47641 acaattcatc tccagcttca cgagtaaaga ttttcacatc gtgaacgata ccgccgccgc
    47701 catgtggtac acgtaatgat gtatcgcgga cttcacgagc tttttcgcca aagatcgcat
    47761 gcaatagacg ttcttctgca gataattctg ttaccccttt tggcgtgact ttccctacaa
    47821 gcaaatcgcc atcttggact tctgcaccaa tacggatgat acccatttcg tctaaatctt
    47881 ttaatgcgtc ttccccgaca ttagggattt cgcgtgtgat ttcttcaggt cctaattttg
    47941 tatcgcgggc ttctgattca tattcttcaa tatggataga agtgtatacg tcatctttta
    48001 ccaaacgacg gctcatgatg atcgcatctt catagttgta cccttcccaa gtcatgaaac
    48061 caactaaaac gttttggcct agagccattt cgccttgttc catagatggt ccgtctgcca
    48121 gagtatcccc tttttcgact ttctcaccca aatgaacgat tggacgttgg ttgtagcttg
    48181 ttccggagtt tgaacgacgg aattttgtta catcgtattt atctaatgca ccgttgtcgc
    48241 ggcgtacgcg gatttcagaa gcatcaacgt attcaacgac accgtcatgt ttacataaca
    48301 aagcagctcc tgagtcatgc gctgatttgt attccatacc agtaccaacc catggtgctt
    48361 gaggattgat caacggcact gcttgacgct gcatgttggc acccatcaag gcacggttgg
    48421 agtcatcgtt ttccaagaaa ggaatacatg ctgtcgcaac ggcaactact tgtttaggtg
    48481 atacgtccat gtagtctact ttatcaatag atacttctaa gttttcactt tgagcacgag
    48541 ccataacaac gtcttgagca aatgttccat cttcattcaa tgggctgttt gcttgggcta
    48601 cgatgtaatg gtcttcgata tcagctgtca agtagtcgat ttggtcagta acacgacctg
    48661 tttcacggtc tacacgacga taaggtgttt cgataaatcc gaatttattt actttcgcat
    48721 aactggacaa actattgatc aacccgatgt ttgggccttc aggagtttcg atcggacaca
    48781 tacggccata gtgggagtag tgaacgtcac gaacttcata accggcgcgg tcacgagtca
    48841 atccgccagg tcctaaggct gaaagacgac gtttgtgtgt caattcgcca agagggtttg
    48901 tttgatccat gaactgtgac aactgagaag aaccaaagaa ttctttgata cttgccacaa
    48961 ctggacggat attgatcaat tgttgaggtg tcaatgtttc agtatcttgg atcgacattc
    49021 tttcacgaac cacacgttcc atacgtgcta gcccgatacg gaattggttt tgtaaaagtt
    49081 caccgactga acggatacga cgatttccta agtggtcgat atcatcgaca ttgccgatac
    49141 cttccatcaa gttcaagaaa tagctcattg aagcaatgat gtcggctgga cgaaccgttt
    49201 ttacagctgc ttctggatag ccgtttccga tcacgtttac ttcacgttca gggtctcttg
    49261 gtgaaaatac tttgatgact tggacagtca ttggatctgt gaccacaccg tcttctgatg
    49321 gatagtaagt cactgaattt aggccattat caatgaaagg agctagtgtt tccatgactt
    49381 ggtgagtcag aactgttcct ttttcaacga tgatctcgcc tgtttctgga tcaactaatg
    49441 tttcagctaa tgtcagattc aatagacgtg ttttcaaatc taattttttg tttactttgt
    49501 aacgaccaac gtttgctaag tcgtaacgtt ttggatcgaa gaaacgagca ttcagcaagt
    49561 tacgtgagct gtctgctgtt tttggttcgc ctggacgcaa acgttcgtaa acgtctttca
    49621 aaccttcttc tgttcttgag tcgcttgcgt ttttatgcaa gtctttttcg actgtattgc
    49681 gtaatgtttc gctgtcgccg aagatttcaa agatcgtatc atcggaacca aatcctaacg
    49741 cacgaactaa tacggttaaa ggaatcttac gtgtacggtc gatacgtaca taagagatgt
    49801 cttttgcatc agtttccatt tctagccaag ctccacggtt agggataaca gtagaaccga
    49861 atccttcttt tccgtttttg tcgacttttc catggaaata gacacctggt gaacggacta
    49921 actgagaaac gattactcgc tctgccccgt tgatgatgaa tgttccttgt tctgtcatta
    49981 atgggaaatc accgaagaat acttcttgtg ctttgatttc gccagtctcg cggtttgtca
    50041 aacgcaatgt tacatgtaat ggtgcagagt agtttgcatc atgcgcacga gcttctgcta
    50101 ctgtatactt tggttctttc aattcataat ctacaaattc caaagataga ttgccattga
    50161 agtcatcgat tggcaaaatg tcttcaaaca tttctctaag tccctcatct aagaaccatt
    50221 ggtaagagtc tgtttgaatt tcgatcaaat ttggtaattc caacacttca ctgattcttg
    50281 cgaaacttct acgttcgcga tgttttccgt attttactac gtgtccagcc aagctcttca
    50341 cccctctaaa atgtcattca aaaagactac ccgatcaatt gttacaataa tatttcaaat
    50401 attattttta ggtaacaaca gacatttttt gcggctttta ggcaaaaaaa aaccaaaaat
    50461 agaacattct cttgaaacct tacttcgtga gcttctactt ttgtttcctt atattaaagc
    50521 cgaaacggac aatatttcgt ttctgccttt tcttcatcag atagtttttg caacttcata
    50581 tactacactt attttctata aaagtcaaca cttcctggcg tttcttctgc tttttcgcaa
    50641 cattttctta atgttttcaa ttttatgttt tcaattatct gacaattctt aattgacaga
    50701 cctttttatc tcggttatac tttagaaaat tcattttgtg gaggaacttc tatgcgaacc
    50761 aacatcaacc aaatcgcacc aacacaactg aataactttt actttagcta ctttagatag
    50821 gtttgtattc atcatgatgg atacaaacgt taaacgacag tttgtatcta tgatggctaa
    50881 agaactttgt attgcagcaa aaagccacgt agacaaaatg ctaagtggct gagcagtgaa
    50941 aatacaaagt aaaagtatca agcattctac tttttcaatt tattttccga cttttcaatc
    51001 catttggaca ttttgtctga atggattttt tgtttcccaa aattaaggag gaaaaagaaa
    51061 tgaaaaaaaa tataatcatc ggattaggcg ctgccctgct actagcttta ggaggttgcg
    51121 cacaaaaaga caattccgca gaggcatcag atggacaaaa aacaattggc gtattgcaac
    51181 ttgtacaaca taactcgtta gatgctgcct ataaaggatt caaagaagga ttagcagaag
    51241 aagggtataa agaaggcgat aatctaacaa tcgattatca aaatgcccaa aacaatcaag
    51301 acaacctgaa aagtatgagt gagaaactcg tcaaagaaga tcctgatttg ctacttggaa
    51361 tcgccactcc agcagcacaa tctttattaa atgaaacaac cactatcccg atgactgtca
    51421 cagcggtcac agacttggaa caagcccatt tagtcacatc caatgaaaaa cctggcggca
    51481 atgtgactgg cacgacagat atggtgccaa tcgaaaaaca aatcggctta ctgttaaata
    51541 tcgtgccaga cgccaaaaca atcggcatca tgtataacaa cggtgaagca aactctaaga
    51601 tccaagctga tttggcagaa aaagaattga aaaaagcggg cgtcaaagtc aaagtactga
    51661 cagcaaattc cacaaatgat gtccaacaag tgacgaaaag tctagctaaa gatgtagatg
    51721 gaatctatat tcctactgat aacacgttcg caagtgcggc aagtgttgtc ggtgaagtcg
    51781 caaaagaaac aaaaacacct gtcgttgctg gcgcagttga tcaagtcaaa gacggcggtc
    51841 tagcaacagt aggaatcgac tacgaaagct tgggtaaaca aacagggatc atggcagcaa
    51901 aaatcttaga cggcaagaat ccaagtgaac ttcctgtcga aacagcgaat gatttggaac
    51961 tgtatgtcaa taaagacatg gccaaagcat taggcatcaa tccagacagc atcaaagaag
    52021 ctgaataaaa cacaggagga ttctcatgac aaatttgctc tctcttttct tatcatctgc
    52081 atcgcaaggg gtcttatggg ccctacttgc gattggtgta tacgtcactt tccgtatctt
    52141 ggacattgcc gacttgactg ctgaaggaag ctttccttta ggtgcaggga tcgcggcagt
    52201 aagtattaca aatggctatc atccattgac agcttgtctt ctaggctttt tagggggtgc
    52261 ggcagcaggg cttgtttccg gactgcttca cacaaaattg aaaattcccg cccttcttgc
    52321 agggatcatc accatgactg gtttatattc tgtcacatcc cgtgtgatgg gtgcgccgaa
    52381 catctcttta ttgggtcagc caacgatctt tcattgggtc gagtcattcg gcataacaaa
    52441 agacaacgct gtactgatcg tcggtctgct ttttgctttg atcgttgtat gtttacttgt
    52501 tttgttctta cgtacagaaa caggacttgc tattcgtgca actggcgata atctggcaat
    52561 gagcgaagca aacgggatca acacagataa tatgaagatc atcggttata tgatttctaa
    52621 tggatgcatt gctctttctg gctccttgct tgcgcaaaac aacggctttg ctgatttaaa
    52681 ttctggtatt ggaacgatcg taattggact tgcttctatt atcatcgcag aagttttgtt
    52741 acgtaaccag ccactatttc tccgtctctt gactgtcgtt ttaggtgcgg tcatttatcg
    52801 ttttatttta gcgttagtct tcgaactgaa tgttgaacca agtgattcga aacttgcttc
    52861 tgctttcgtg ctagtgatct gtctttcttt cccgcagatc cagcaaaaat tccatttacc
    52921 tcaaaaaaag aaaggcggta gtgtcaaatg aatgacgtct taacattgga aaatctccat
    52981 catacctttg aaaaaggaac gatcaacgaa aatcatgtcc tgaaaggcat taatctttcc
    53041 ttagatcccg gcgacttcgt gacgatcatc ggtggaaatg gggctggtaa atctactttg
    53101 ctgaacagca tcgccggtac attttctgtc gatcagggtc aaattttatt gaatggaaaa
    53161 aatatcacga aaaaatctgt tgtcgaacgt tcgaaatcca tcagtcgcgt attccaagat
    53221 cctaaactag ggacagccgt tcgtttaacg gtagaagaaa atcttgctct tgctatgaaa
    53281 cgaggaaaaa aacgcggctt cttccgtggt gtcaaaccac aagaccgaac atttttcaaa
    53341 gaccagctgg ttcggctaaa tttggggttg gaaaatcgtt tatcctcaga aatcggtttg
    53401 ctgtctggag gacaacgtca agctattacg ttattgatgg ccacattaca gcgtccagaa
    53461 ctgatcttat tagatgaaca cactgcagcg cttgaccctg ctacttccaa aacggtgatg
    53521 gaattgacag aaaagctgat cactgagcag aatctcactg cttttatggt cactcatgac
    53581 atggaagacg cgatccgcta tgggagtcga ctgatcatgc tgcatcaagg aaggatcgtc
    53641 gtagatatcc agcaagagga aaaacagcag ctcacagtgc cccaattatt agcgttgttc
    53701 aaacaaaaca gcggcacggc attaaaagac gatcaagtac ttttatcttc ataatcagaa
    53761 agaggatggg acaaaaaatg aacgcccacc ctcttctttt ttctctttcc ttctttcgtt
    53821 tttgctttat gtatcaaccg ttgtttcttc gaaaactatt ttgttctctc cttcttcctg
    53881 atagaatgga tgggaaagga gcttgatgcc atgacaacga aagacaaggt acttcaatta
    53941 ttgaaaaaga caccagattt tctttccgga gaaaagttgg cacagcaact ggaagtttcc
    54001 cggacaagta tttggaaagc catcaaagaa ttggaaaagg caggctatcg ttttgagcac
    54061 gggcctacag ggtatcgtta cctgccctct gacgtactag atgcaaaaga aatccagcaa
    54121 gagctacggt cgtttattcc tgatttgaaa gtacaaacga tgttgacttc tgaatctacg
    54181 atgaaagatg tcaaactggc agcagctcaa ggagattctg tttcgaagtt atttgttgct
    54241 gatacacaag aacaagctcg tggacgtttt ggacggcctt ttttcgctga acctggacga
    54301 ggaatctaca tgagtctctt gctccatcca gacaaacggt ttgatgaatt gcctcaatat
    54361 acgatcatcg cagccagtgc ctgtgtgaaa gccattgaat ctgtaaccgg tcgttctgct
    54421 tcgatcaaat gggtcaatga tatctacatg gatggaaaaa aagtctgtgg gattttatct
    54481 gaagcagtca gtgatatgga aagcggcagg atcagtcata tcatcattgg gatcgggctt
    54541 aatttttctg ttcctcaaaa tcattttcca gctgatctcc aagaaaaagc catctctgtc
    54601 tttcccgacg gacaagctag tgtcacaagg aatcagctaa tcagcaaaat ctggcaagaa
    54661 ttgttcactt atctttctca cccagaaaaa gcgttggact tctataaaga aaaatcattc
    54721 gtattgggaa aaaccgtgtc gttcaatcaa aaaggaacga cttatgtcgg tcttgcaaaa
    54781 gaaatcggtg atcatggcga actgatcgtc caaacaaatg aacagaagat gagtttgtct
    54841 tctggcgaaa tcagtctcac atctatccgt acgcaataat tatcagattt cacaaaagga
    54901 cacctgatct catacagtgt ccttttttct gaattctctt caaaagactc tccttattct
    54961 atcagctgac agtttctcta tcctctagaa aaaggtattc taaaaatatc tataaagcat
    55021 ggtacacttt ctttaaatga atcaatgcaa aaaacaagag agtcatcagt ttacacgatc
    55081 aaaagagata gcaggccgct tcctttttca atcttataga tagaccatgg gtaacgataa
    55141 aaacaaaaaa gaacttgcga cttattttgc cgtaagttct tttttagcta gtgccttaat
    55201 ctcttaatcc caacaaacgt ctcgcataga tcacctgacc agagtgcata gcagcatcat
    55261 caataataga aacgagacgc attcctcgtg tgactggtgg tgtccagttc tcgtcaatta
    55321 cttcatctag ctcggaaggt tccagccttc ttaagtaaga aatagcaaaa tcagcagctc
    55381 ctcgcaagta tcctagcaga tcttctattt gattagcttg gatctgcttt gcttgttcca
    55441 gactatgctt ccaatcttgt tcgttatctg ctatcgtcat cggaaaccgg ctttcccagt
    55501 cttgactatg ccaaattgga gaagttcctg ctaaatcagc aatctggaaa tctaattctc
    55561 gagcggtatg ccaagccagc caagtcattg atttgatctg cggggctcta tcttccactg
    55621 gaaaacgatt ggcctcctca atagagacgc cttcaaacaa acgttcaaac cgatcgtatg
    55681 cccgatccac actctcgcat agcatatcta aataatccat ttattttcct cctttttatt
    55741 tatcctactt actttttcct aattctagga tacctactta tatgttacta cacaccctta
    55801 ttttttacac tttaacagtc accatcatca atagtttgga gattgaaaga aaaagatagt
    55861 gtcgaactat caattgaaca agaagcaaca atatgaacgt ttcattaata ttctttaaat
    55921 aaacaatgat ttttcaaacg aacagtttaa gactaggaga aaaagagtat aataggaaaa
    55981 tgtttgaaag gaaaggaagg ggaaaaatga aaaaaagggc aagtttacta gtcctagttg
    56041 ctttgttgtt caatatcttt tcgtatggtg tggccgtttc agcggaaaca tacattccta
    56101 aagaccctgg gaatatttat aatgatctaa ctggtaacta tggcttgtta ggaattgcta
    56161 gtcaattcca cgtatttgct aaaaataaga caactgtgaa tgcacataca gacggaaata
    56221 tagcaacaca tgaacttgat gcaaaaaata attttggtac agagcttcat gaaggtttat
    56281 tgaaccaaga aataaattat atacaaaaaa ctgattcttt cgctaattct tcaggcatac
    56341 ctacaggtag cacaagaatg aataaatttg tcgttggcag taacgtggat gtagcacttc
    56401 aagatggtca tcctacagtc aatggatcca ggcttgatca cttaactcca gatgattttt
    56461 ataaagatcg tgctgggcat gaatatattg atttcgagca ggaatttgct aaattgaatg
    56521 tagcagcaaa tgatcttgca acgatcactc cagctaaaac atatactgct gcagattttc
    56581 cagacatgaa caatcggaca atcgatttaa ctgatttatc agataccggg tttttattgg
    56641 taaatatcga tgcagaagtg ttaacgatga atacgccact tcaaatcatt aatccaaatg
    56701 atcaagtagt tgtatttaat gtcatcaaca gttcttctgc attgaacgta cagtcaccaa
    56761 tcaaatacaa tgatcgttca aatcatgaaa cagaagattt ttcggatgcg aatatctctt
    56821 ggaattttgg aaatgagatg actgatttga caatcagtgc tccttttcaa ggaacaatcc
    56881 ttgcgcctaa tgctactatc cgcattactc aaaaccaaga cggaacgatt ataggaacaa
    56941 atgtgatttt agatgcagct accaatcgtt gggatcctaa cgaaatattt atcagcgaca
    57001 atggtacaga tacgacagac acaagcgaca gtacagatac atctaccaca agtgatagct
    57061 cagattcatc a
//
LOCUS       DAPBAF010000014        56010 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.014, whole genome shotgun sequence.
ACCESSION   DAPBAF010000014 DAPBAF010000000
VERSION     DAPBAF010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 56010)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56010)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56010
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.014"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(24..722)
                     /locus_tag="RD451_000984"
     CDS             complement(24..722)
                     /locus_tag="RD451_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HDT7566263.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(715..2067)
                     /locus_tag="RD451_000985"
     CDS             complement(715..2067)
                     /locus_tag="RD451_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HDT7566264.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(2290..3690)
                     /locus_tag="RD451_000986"
     CDS             complement(2290..3690)
                     /locus_tag="RD451_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HDT7566265.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            3851..4588
                     /locus_tag="RD451_000987"
     CDS             3851..4588
                     /locus_tag="RD451_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HDT7566266.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            4713..5192
                     /locus_tag="RD451_000988"
     CDS             4713..5192
                     /locus_tag="RD451_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HDT7566267.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            5189..5956
                     /locus_tag="RD451_000989"
     CDS             5189..5956
                     /locus_tag="RD451_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566268.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            6186..6755
                     /gene="lepB"
                     /locus_tag="RD451_000990"
     CDS             6186..6755
                     /gene="lepB"
                     /locus_tag="RD451_000990"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HDT7566269.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(6859..7461)
                     /locus_tag="RD451_000991"
     CDS             complement(6859..7461)
                     /locus_tag="RD451_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HDT7566270.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            7567..8036
                     /locus_tag="RD451_000992"
                     /pseudo
     CDS             7567..8036
                     /locus_tag="RD451_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325408.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            8142..8726
                     /locus_tag="RD451_000993"
     CDS             8142..8726
                     /locus_tag="RD451_000993"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HDT7566271.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            8729..9802
                     /gene="prfA"
                     /locus_tag="RD451_000994"
     CDS             8729..9802
                     /gene="prfA"
                     /locus_tag="RD451_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HDT7566272.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            9795..10634
                     /gene="prmC"
                     /locus_tag="RD451_000995"
     CDS             9795..10634
                     /gene="prmC"
                     /locus_tag="RD451_000995"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HDT7566273.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            10627..10806
                     /locus_tag="RD451_000996"
     CDS             10627..10806
                     /locus_tag="RD451_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566274.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            10828..11853
                     /locus_tag="RD451_000997"
     CDS             10828..11853
                     /locus_tag="RD451_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HDT7566275.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            12028..13272
                     /locus_tag="RD451_000998"
     CDS             12028..13272
                     /locus_tag="RD451_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HDT7566276.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            13425..14372
                     /locus_tag="RD451_000999"
     CDS             13425..14372
                     /locus_tag="RD451_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDT7566277.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            14506..15135
                     /gene="upp"
                     /locus_tag="RD451_001000"
     CDS             14506..15135
                     /gene="upp"
                     /locus_tag="RD451_001000"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HDT7566278.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(15274..15516)
                     /locus_tag="RD451_001001"
     CDS             complement(15274..15516)
                     /locus_tag="RD451_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566279.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            15637..15709
                     /locus_tag="RD451_001002"
     tRNA            15637..15709
                     /locus_tag="RD451_001002"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:15670..15672,aa:Thr,seq:cgt)
     gene            complement(15828..16466)
                     /locus_tag="RD451_001003"
     CDS             complement(15828..16466)
                     /locus_tag="RD451_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDT7566280.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
     gene            complement(16589..17221)
                     /locus_tag="RD451_001004"
     CDS             complement(16589..17221)
                     /locus_tag="RD451_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HDT7566281.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
     gene            17572..17871
                     /locus_tag="RD451_001005"
     CDS             17572..17871
                     /locus_tag="RD451_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HDT7566282.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
     gene            18366..20531
                     /gene="acm"
                     /locus_tag="RD451_001006"
     CDS             18366..20531
                     /gene="acm"
                     /locus_tag="RD451_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HDT7566283.1"
                     /translation="MKKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVD
                     PTNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVG
                     TLTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATV
                     NVTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRL
                     DPSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRK
                     IMVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGE
                     LKIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVK
                     EKEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPS
                     IYFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGN
                     DYVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQ
                     HKEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNI
                     SIPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITN
                     KSKSILPKTSSKKSSFAVIIGLLIVTICAGIFLQKYKKV"
     gene            complement(20803..21288)
                     /locus_tag="RD451_001007"
     CDS             complement(20803..21288)
                     /locus_tag="RD451_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HDT7566284.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     misc_binding    21378..21723
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            21768..22409
                     /locus_tag="RD451_001008"
     CDS             21768..22409
                     /locus_tag="RD451_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HDT7566285.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIIMKQVEGKLNYYR"
     gene            22428..23063
                     /locus_tag="RD451_001009"
     CDS             22428..23063
                     /locus_tag="RD451_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HDT7566286.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            23081..23896
                     /locus_tag="RD451_001010"
     CDS             23081..23896
                     /locus_tag="RD451_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HDT7566287.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            24215..25651
                     /locus_tag="RD451_001011"
     CDS             24215..25651
                     /locus_tag="RD451_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDT7566288.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            25840..28287
                     /locus_tag="RD451_001012"
     CDS             25840..28287
                     /locus_tag="RD451_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HDT7566289.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            28517..29584
                     /gene="rlmN"
                     /locus_tag="RD451_001013"
     CDS             28517..29584
                     /gene="rlmN"
                     /locus_tag="RD451_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HDT7566290.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(29777..30880)
                     /locus_tag="RD451_001014"
     CDS             complement(29777..30880)
                     /locus_tag="RD451_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HDT7566291.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            31433..31981
                     /gene="aac(6')"
                     /locus_tag="RD451_001015"
     CDS             31433..31981
                     /gene="aac(6')"
                     /locus_tag="RD451_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HDT7566292.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
     gene            32527..34188
                     /locus_tag="RD451_001016"
     CDS             32527..34188
                     /locus_tag="RD451_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HDT7566293.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(34258..34605)
                     /locus_tag="RD451_001017"
     CDS             complement(34258..34605)
                     /locus_tag="RD451_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HDT7566294.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSSLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            34689..35630
                     /locus_tag="RD451_001018"
     CDS             34689..35630
                     /locus_tag="RD451_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7566295.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            35631..36674
                     /locus_tag="RD451_001019"
     CDS             35631..36674
                     /locus_tag="RD451_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7566296.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            36680..37750
                     /locus_tag="RD451_001020"
     CDS             36680..37750
                     /locus_tag="RD451_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7566297.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            37740..38693
                     /locus_tag="RD451_001021"
     CDS             37740..38693
                     /locus_tag="RD451_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDT7566298.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            38705..39715
                     /locus_tag="RD451_001022"
     CDS             38705..39715
                     /locus_tag="RD451_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDT7566299.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(40000..40821)
                     /locus_tag="RD451_001023"
     CDS             complement(40000..40821)
                     /locus_tag="RD451_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HDT7566300.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(40918..41196)
                     /locus_tag="RD451_001024"
     CDS             complement(40918..41196)
                     /locus_tag="RD451_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566301.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            41464..43473
                     /gene="metG"
                     /locus_tag="RD451_001025"
     CDS             41464..43473
                     /gene="metG"
                     /locus_tag="RD451_001025"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HDT7566302.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(43952..44539)
                     /locus_tag="RD451_001026"
     CDS             complement(43952..44539)
                     /locus_tag="RD451_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566303.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            44714..46036
                     /locus_tag="RD451_001027"
     CDS             44714..46036
                     /locus_tag="RD451_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDT7566304.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            46191..46967
                     /locus_tag="RD451_001028"
     CDS             46191..46967
                     /locus_tag="RD451_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HDT7566305.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            46960..47529
                     /gene="rnmV"
                     /locus_tag="RD451_001029"
     CDS             46960..47529
                     /gene="rnmV"
                     /locus_tag="RD451_001029"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HDT7566306.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            47522..48406
                     /gene="rsmA"
                     /locus_tag="RD451_001030"
     CDS             47522..48406
                     /gene="rsmA"
                     /locus_tag="RD451_001030"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HDT7566307.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            48857..49486
                     /locus_tag="RD451_001031"
     CDS             48857..49486
                     /locus_tag="RD451_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566308.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(49610..50719)
                     /gene="ugpC"
                     /locus_tag="RD451_001032"
     CDS             complement(49610..50719)
                     /gene="ugpC"
                     /locus_tag="RD451_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HDT7566309.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            50928..51350
                     /gene="mgsA"
                     /locus_tag="RD451_001033"
     CDS             50928..51350
                     /gene="mgsA"
                     /locus_tag="RD451_001033"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HDT7566310.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     gene            51673..52209
                     /locus_tag="RD451_001034"
     CDS             51673..52209
                     /locus_tag="RD451_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HDT7566311.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(52249..54012)
                     /locus_tag="RD451_001035"
     CDS             complement(52249..54012)
                     /locus_tag="RD451_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7566312.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(54015..55730)
                     /locus_tag="RD451_001036"
     CDS             complement(54015..55730)
                     /locus_tag="RD451_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7566313.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
BASE COUNT        18741 a         9822 c        11362 g        16085 t
ORIGIN      
        1 tcacattccc ctttttcgaa taactaggct gtttgtcctt caagataggg cagatccaat
       61 tctttaccgt aacgttgttc taaagctagg cggatcaaac gagctgccag gttctcattt
      121 cttgcaagga taggtccatg gaaataagaa ccgaagacat ttcggtaaat gacaccttca
      181 gattggtctt caccattatt tccttgacct tgtaccactt tccccaaagg tcgttcacct
      241 tcacctaaga aagtccgacc attgtggttt tcaaatccat aataagtttc attgaattct
      301 tcgttatgga taacgatatc accgataaac cggttatttt cctgacttaa cgtgtagtga
      361 tccagtgcac tgattccttg gatcttttct ccattagctc ccatgtagta gtgacctagc
      421 aattggtagc caccacaaat ggctaacatg acgccatcat tttcgatata gttgatcaaa
      481 gaatctttct ttttctggat gtcttttgaa atgattaatt gctcaaagtc ttgaccaccg
      541 ccaaagaaaa ccaagtcata tttatcagca tcaaaaggtt catgtatact aacgatctcc
      601 gtatggcaag aaacccccat tttttctgct atatatttca acatcaaaag gtttccgtta
      661 tcaccatatg tgttcatcaa atttccataa aggtgggcga tattgagttc ataattagcc
      721 acggttcatt cctcctttga taaatccttg agcagctagt tctttacgaa gctgcaatac
      781 agcagtgtaa gtagctaaaa tatagacatg ctcagttggc aattctttga ttttttcgat
      841 tacttctggt aattcttttg tttctgtcaa tttattttct ggaatcccgg caacttttag
      901 acgtaaagtc atatctgtat gacggtctcc tccagaaata acagctggga tatccatatc
      961 ggcaaagttt tcaaaattac catcccaaat ccagctgaca tcgattccgt ctgcgtaatt
     1021 ggcatttaat aaagccacta aagaaaatgg ataaggagct agaccaatca tatcgattac
     1081 ttgattgata cctacaggat ttttgacaag tactaatgta cattttttcc cattgatatt
     1141 gatgacttct tgtcggccga atactttctc gtcatatcct aaaccttgtt tgattttatc
     1201 aggatcgaca ttgaagtact ctgccactgc agtagctgct aaagcattgt agacattata
     1261 cataccgcca acttcgattc cgtattcatg accatcgatc acgaaatctg ctgacacatt
     1321 gtccatccgt accatatcag ttaatcgata atccaattca ggacgtttga agtcacaatt
     1381 tggacagtaa tatttcccta agtttgcata agtgatcatt ttataatgca agatgtgatg
     1441 acaatttgga cataagacac cgtctgtatt gtaatgagcc atttgttcac gatcttcttc
     1501 atggtcaaag ccataatatt ttctaggatt gactgtttcg atagaattga agattggtga
     1561 atcaccgtta ctgataatcg ttgcatttgg tgactttgcg gcaccgtcta caatcatttt
     1621 ataggtcgta tagatttctc cataccgatc catttgatca cggaaaatat ttgtaaataa
     1681 gaacagttct ggtttcatat attctgtgac tttgctcaaa cttgcttcat ctatttctag
     1741 gacagcaaac tttttctgtc ctttttttgg ttttgcctgc aagaaagtcg atacaattcc
     1801 ctgtaccata ttcgcaccag tagggttggt tagaacttca tcgaattgct ggcgcaaaat
     1861 attgactgtt aaagcggtag tcaatgtttt accgtttgtt ccggtgacaa cgacgacttg
     1921 gtagtctttt gccaaactat ctagtatatg tggatcgact ttcagcgcta gtttacctgg
     1981 taaacttgat ccgcctttaa aaaaagtttt taatgcccat tgcgacgttt ttccaactgc
     2041 aatcgcaaaa tgactgcgta ttcccattat gtaacctcca aaaacgattt gctgacgaat
     2101 aaattcaact aatcatacca tatgttgaaa aaaaggttaa attgcttttc ttattcttaa
     2161 gaaaaggtta cggctgaaag tgcatgaaat cggacaaaat cgcatgattt aacaaaaaaa
     2221 cagcttgaaa caaaatgatt gtttcaagct gctgtgattt tattattccc tcttacctat
     2281 attcccattt taaccgataa taattttctc gcttggatat tcatagccta gatctcgtgt
     2341 ttcttttggc acgaataaca tcaatgtata tagcattccg atccgcccaa taaacatcag
     2401 tgtagcaatc gtgattttgc ccacaacaga caagtctccg gtaatcccta aagataaacc
     2461 agttgttcca aacgcagaag ttacttcgat gatgatcgag atcagcgttt gttcttctgt
     2521 agcagataaa aaaacgatac aaaagaaaca cataccaaga gaaagcataa agacaacgac
     2581 tgattttcgc acatcatctt gatcgattct ccgtccaaaa atattgatgt tatcttcact
     2641 tttgaggaag gaatatagat acaaaccgat gattgctaca gtagttgttc gaatcccgcc
     2701 gcctacagaa ctaggactgc atccgataaa catcagtaaa gaaaaaatga tcagtgttgt
     2761 gatttgaaaa tcacccaaat cgtgaatctg cagaccagca ttacgagtcg taatcgaata
     2821 aaacatcgaa ttgatccatt tgacactcat attggaatct tggaataaat ggtccttttc
     2881 caatagataa atcaagacag ttcccgaaac aaacaagata acaaaagcta acacagctaa
     2941 tttggtaaac aaggaaaaac gaaacggaag cttcgcattg gaacgtttgt ataatagcca
     3001 ttcccggcac tccatcaata caggaaaacc aattcctccg acaaaaatca aaaacatgat
     3061 caggatcaag aaaaaatagt catgtgcaaa gggcttgatg gaatccccag tgacgtcaaa
     3121 cccagagttc gtgacagccg atatcgcctg ataaaaaccg taaaaaacgg catcacgcca
     3181 acgatcaaaa tagcctctgt aataaaaata aatagaaaag aatgtcccaa aaagtaattg
     3241 aaaccagatt aaaatagcaa aagtgatccg aatcagtcgg acgataccag acaaacgcgg
     3301 ttgattcata tccgtcatga tcagctgtcg ctgtttcagt gtgatccgtc gtttagaaaa
     3361 aatgacaaaa gcagtagaaa tcatcatgat ccccaaacca ccaacttgaa ataatatttc
     3421 cagcagtata ataccgttat cattgaacac agaattgata tcaaaagtcg atagtccagt
     3481 cacactcact gtactgattg ccatgaacag catgtccaca aaagaaacat ggctatctgg
     3541 ttcgcgaaaa atcggcatat aaaatagaac gagtgataag accgtcatca atatataata
     3601 aaaaacgatg atttggatcg atgagaaatg attggcagca aacttctgtc ctcgccgctg
     3661 cagccttcga aagaataaat caacatgcac agtactatcc tcctgacaat agtcgtttct
     3721 accagtatac aaggggaatt aggaatactc aaagaaatta tcaaacagat aacaatacag
     3781 ctttcgatta aaatagaaat ggcttataat aaggaaaatc ctagaaaaaa gaaggaggag
     3841 gaataacaaa ttgattaatg ctcaacaaat cgtagaaaaa atgaaaaatc aaaaaataaa
     3901 ttatgataca gttctgaaaa aaatgatcat gcaatgggag aaagaagaag taaagcctaa
     3961 gatattaata catacatgct gtgctccttg cagtacgcac acattggaat tcatgtctca
     4021 atatgcagag atcacgttat ttttttcaaa ttcgaatatt catcctaaaa gtgagtattt
     4081 gcgaagatta catgaacaaa aacgatttgt agaccaattt aatgagaaaa ctgaccatca
     4141 tgttgcgcta atcgttgatg aataccgtcc aaatgaattc accaaaatgg ttttaacaaa
     4201 ccatcttgaa aacgaaaaag aaggtggtgc tcgctgcagt gcatgcttca atatgcgatt
     4261 agatcttgtt gcgcaaaaag cgcaagaact aggatacgat tactttggaa gtgccctgac
     4321 catctcgcca aagaaaaatg cagctttgat caatcagatc ggaatggata tccaaaagat
     4381 ttacgggaca caatacttgc caagtgattt caagaaaaac aaaggctatg aacgctcttt
     4441 gcaaatgtgc aaagagtatg atatttatcg ccaatgttat tgtggttgcg tgttcgctgc
     4501 caagcagcaa ggatgcgatc tgaaagaaat caatcgggaa gcaaaagctt acttaaaaac
     4561 atcaaccgta gtttttgagg aaaattaaag aaatctttcg gaaaaacgta agaaaaaaat
     4621 aaagaattta tggtagaaat aaggtagact gtataatttg tccgtagtaa agtaaggaaa
     4681 caagaataaa tttcaatgaa ggaagagata agatgcgaaa agtagcacct attttgaagc
     4741 caatcgctgt attaacaatc tcgacgattg tcgcgactac tacaggtatt gtgaatagtt
     4801 ccagctaccg tgcaccaagt tcaagttcta gtactgtaga agaaacaaca ccaactactt
     4861 cagtctcgac atctgaacca acaacaacgg aaagtttgaa tgaaaccact acgacaagta
     4921 catgggacga tacaacaact agttcgtcgt atgatgagac atatacaact gacagctcaa
     4981 gcgaaacaag taatacggta ccagatggca ctccatcgga ttcaaccaat ccaagtacaa
     5041 gtccggatac aagtgctagc tccgaaacga taccaagcag tacgactgta gatgataaca
     5101 cgcaaaatga tgatgcagca cgtacagcac agcaaaacca agattcagga aatacccaaa
     5161 cgtataacca gcaagcaggt gattctcaat gacattttta ctagacctta tcaacggggt
     5221 gcataaattc cttggctatt tagacatcag tcctaaatat cttaaccgtg gatatacgat
     5281 tttaagtgtg attcccacgc tttatttatt gagaattgtt tatggacttt ggcaaaacca
     5341 aaactatctt caatttttct tatatggact tgcatttcta gtgcttgttt attttactgt
     5401 tttaaatgta ttttattact ttttagataa aaacacgaaa gccgatgtca ctcagctttt
     5461 tgtgaagtat ttacctgatg aagcgttcaa catccagaca gaagaatcga tagataatgg
     5521 aaattcgatc gataaagtga atacacaaga ggtcatggtt tcttatgacg aagattatca
     5581 attgaaatta gccgagaata tgcggtattt gattggaaat ggtgagatca aaacaaatga
     5641 actcggtcgc atggatggat ttctggtcga tagaaataca ttgtatcctt attactatgt
     5701 caagaaaaca ggagagaaag agtatgttct aaatattgga cgaagctact cggacatgga
     5761 aaaagtaggg accattcgac ttgactcaac agaagacaca ttggaacctg tcggattgtt
     5821 catcgtcggc ggtgattttg tcaaagacgg gttacgctat catgagcctt atcgtctgaa
     5881 attgattgca aaaaaggcac agtcgcagga agaaccagtg gtttatagtc gtagccaaag
     5941 aagaagacat tcataatgtg atgaaacgcc gtgtatcagt ggttgcgata aaaacgttta
     6001 ttcggaataa gggggatgtg acacgtcttt tgtcacgttc cttttttata taacgagaaa
     6061 gataagacga acacatcact tattctttcc tttcatttat aaacattgta gaataaagaa
     6121 agtacaacga agtattgtga aaaaacgtaa taaataacga ggaaaataca agtaggaggt
     6181 aagctgtgaa agaatttttg aaaaattggg ggattttgat ccttgtatta gcggctattt
     6241 tattagctag agtgtacgtg tttacaccag ttactgtaaa cgggcattcg atggacccta
     6301 cattaagtga tggacaacga ttgatttcat ctaagatctc aaactatgaa cgaatggata
     6361 ttattactac aaaggaaccg ggggatgaag aacggatgat tgttaaacgg atcatcggta
     6421 tgcctggaga tacagtcaag atggaaaatg accagttgac cattaatggc aaaaagtatg
     6481 atgaacctta tctggatgag ttcaaaaaag aattttcaga agataagtta caaggagaat
     6541 atgcttatag ctcaggattc caagcacaag cagaaagttc atccaccttt acgagtgact
     6601 ttgaatatac tgtgccaaaa ggaaagtatc ttgttctagg cgataaccgc ttgatttcaa
     6661 aagacagccg aatgtttggg ttagtcgaca aagatatgat ccaaggaaaa gttgttttcc
     6721 gttattggcc tctttcagaa attaaaatca tgtgatgaaa aaataaaaag aagctgtgac
     6781 atgttttttg tcacagcttc tttttccgaa aattccttct tatttcttgg agttgctcac
     6841 tttttttgca atctcatttt aagctttttg gctgatggat aagaaaagcg aagcgttttt
     6901 gttcataaat agcttttccc cacgatggaa ggtatgacta gtagcagaga caaagcccgt
     6961 tttttccaat cgattattca attcttcttg gctaaagcca ttatggactt tcggatgact
     7021 aatttgttca ttcttgtcaa agtctacgat gatcaattga ccgccaggag ctaaaatttc
     7081 ataaagtttt gtaagaatat tctccgtatc aggaatgtgt aaaagtacaa gtgatagaag
     7141 gatgagatta gcttggacag caggaaattc gacagaagca tcagcgtgga tcgttcggac
     7201 atttttcaga tctgctgctt ggatcttttc ttctgccatt ttcagcatag tttctgaagc
     7261 atcggcaatg atcagttctt tgaatctttc cgcaagcggt aaactaacaa gcccagttcc
     7321 gcctccgtaa tccagcagga ctttttggtg gctgtcgcgc ggtagataag tagttagttc
     7381 ttcgcgaata atcttggcta atgcttgacg gtcaggggaa tcataatggt tagcgatgga
     7441 atcaaaaata ttttttgtca tcaaatagct ccttacgtaa aactttgaaa ttttaactta
     7501 ttatagcacg tgaaaagaaa gaaagcatgc tatactcaat tcaaaaaggg agaatctaga
     7561 aagaatatgc cgatatcgtt tgtaaaagat agagaggaaa aaggaaagtg tgtccgagaa
     7621 atattactag acttgcctga gtggtttggg cttcctgaat caacggaaaa atatatcgag
     7681 gaatcaagta aactaccttt atggtgtgaa aaaagaaaag aagaatattt aggctttatc
     7741 actctttcac agacaagtga agatactgcc gaaatctatt ctattgtatg ggaataaaaa
     7801 aagactatca tcaccaagga ttaggaacaa aactttttaa agaagcagaa ggttacgcag
     7861 caaaacatta caaatatttg caagtgaaga ctgtagacga ggggcactac tctatatatg
     7921 atcaaactat ttgtttctac gaatcattag gattttcaag gttggaagtt tttccaaatt
     7981 tatgggatga atggaaccca tgtttagttc ttgtcaaaaa attggaacaa aagtgagcaa
     8041 tagatttaat actaatctgt gcttgatgaa aattctcact gtaaaaaatg ctgaaaatca
     8101 agtataatac cataggaaca aactggaagg tgaaaaagag catggcacaa ctatttttta
     8161 agtatggcgc aatgaatagc ggcaagacga tcgagatcct aaaagtcgca cataattatg
     8221 aagaacaaaa taagccagtt gtcttaatga caagcggtat tgatacaaga gatggtttag
     8281 gcgttgtttc aagccgaatc ggactgaaac gtaatgcgat gccgatattt gaagaaacag
     8341 acgtatttga cgtaattcag aaaatggaaa gcaaacccta ttgtgtgctg atcgatgaag
     8401 cgcaattctt aaaaaagaaa catgtcattg cttttacgag aattgtggac gaattggata
     8461 ttccggttat ggcatttggt ttgaaaaatg attttcgaaa cgagttattt gaaggatcaa
     8521 aatatttatt gctttatgca gacaaaatcg aagaaatgaa aacaatctgt tggttctgcc
     8581 acaaaaaagc aatcatgaat ttacattata ttgatggaaa ccctgtttat gaaggcgatc
     8641 aagtgcaaat tggcggaaat gaagcttatt accccgtttg tcgaaaacat tactttcacc
     8701 catcaatgat tacagaagga gaataagcat gtacgatcaa ttacaagcaa ttgaagaccg
     8761 ttatgaagag cttggagaac ttttaagtga cccagaagtg atttctgata caaagcgttt
     8821 tatgcagctt tcaaaagaag aagcaaacac gcgcgaaaca gtcgaagttt atcgtcgtta
     8881 taaagaagta gtacaaggaa tcaccgatac agaagaactg cttggtgaaa aactggatga
     8941 tgaaatggct gaactagcaa aagaagaatt atctgaatta aaaaaagaaa aagaagtctt
     9001 agaagaaaaa atcaagatct tgcttttacc aaaagatcca aatgacgata aaaatatcat
     9061 catggaaatc cgtggagcag caggcggaga cgaagcagca ttattcgctg gcgatctttt
     9121 caatatgtac caaaagtatg ctgaagcaca aggctggaaa acagaagtga tggaagctaa
     9181 cgttaccgga atcggtggat ataaagaagt gatcatgatg atcaccggag acaacgtata
     9241 ttcgaaatta aaatatgaaa gtggtgcgca ccgcgtccag cgtgttcctt caactgaatc
     9301 gcaagggcgt atccatactt ccaccgcaac agttgtcgtg atgccagaag ctgaagaagt
     9361 agagatcgat attgaagaca aagatatccg tacagatatc tatcatgctt caggtgctgg
     9421 cggacagcac gtcaataaaa cagcatctgc tgtacgtttg actcacttac caacagggat
     9481 cgttgttgct atgcaagatg aacgttctca aatcaagaac cgtgaaaaag caatgaaaat
     9541 cttgcgtgct cgtgtgtacg ataagatcca gcaagaagca caaagcgagt atgatgccaa
     9601 tcgaaaatca gcagtcggaa ctggggatcg ttcagaacgg atccggacgt ataatttccc
     9661 gcaaaatcgt gtgactgatc atcgtatcgg attaactatc caaaaattag atcagatttt
     9721 agcagggaaa ttagatgaga tcgttgatgc attgatcatg tatgatcaaa catcaaaact
     9781 ggaagctatg caaaatgggt aaaatgacct atcgagaagt cctgtcacgg gcttcttctt
     9841 ttttagagga tcatgggaaa gaagcatata gtatccaatt tttatttttg gaacgaaaac
     9901 aatggaaaaa acttgattgg ctccttcata tgaacgaaga gatttcagaa gaagaacagc
     9961 ggttgatcga aaccgatctg cgacttctgc ttgcagatca tccacctcag tatttgctag
    10021 gatatgcaga tttttatgat catcggttaa aggtaactga agcaacactg atccctcgac
    10081 cagaaacaga ggagttagtc gaatggtgtt tagacgagac gcctggtgta ccgttagaag
    10141 tgatagatat tgggacaggg actggagcaa ttgctattag tttgaaagca gcaagaaaaa
    10201 attggcatat atctgctgtg gatctttcag aagaagcatt agaagtagcg aaagaaaatg
    10261 ctcagaaaga aggaacgaaa atcagttttt atcatggaga tacattagga ccagtaatgg
    10321 atcagcaatt tgatgtgatt atttctaatc cgccgtacat cagtcggaat gaatgggaac
    10381 tgatggatga aagtgtccgg tcattcgaac ctaaaatggc cctttttgct gagaacgatg
    10441 gattagctat ttatgaaaaa atagcagttg aagcaccaag cgtactaaaa tcaaatggaa
    10501 agattttttt agaaatcgga tttcgccaag gtgaagcagt aaaaaaaata tttcagcaag
    10561 catttccaga taaaaaagtg gcgataaaaa aggatctttt tggcaatgaa cgaatgatcc
    10621 aagtttatgg ttgaagttgt ggatgaaaaa ttttttattt gtttttttat tataaaaaaa
    10681 cacttatttg acaaggatgt aaacgacttt ttggtttatc aacaagttta tccactattg
    10741 acaaatagat tatccacaaa cagtggaaaa cttgaggata aactcagaca aaataagaat
    10801 gtatgaaaaa ggggttgtgg ataaactgtg gaaacgaaac gatatgatga aacagaattg
    10861 caagaggcag ccgaagcact gaaagaagga gaacttgttg cttttcctac cgaaacagta
    10921 tacggattgg gcgccaacgc tcttttacca aacgctgtca agaaagtgtt ttctgtaaaa
    10981 gggagaccgc aagataatcc attaatcgtc catgtcgcct cttttgaaca agtaaaagag
    11041 tatgtggaca actttcatcc ggcagcagag aagattgtga agaacttctg gcctggacca
    11101 ttaactttga tatttaagat caaaaaagac actttgccct cagttgtgac gggaggatta
    11161 tccacagctg catttcgtat accggataac aaaaaaacac tagaagtaat cgaactttcc
    11221 ggtgttccgc ttgtcggtcc aagtgcaaat acgtcgggaa aaccaagtcc aacgactgca
    11281 gatcatgtat atcatgatct acaaggaaaa attaccggga ttattgatga tggagctacg
    11341 cgaattggtg tagaatccac tgttcttgat ttaagtgatc caacagccat gcctatgatt
    11401 ttacgaccag gtgcagtaac gaaagaacaa atcgaagcag tcatcgaatc tcctgttgct
    11461 attgatcagc atcttgtaaa agaaaatgaa acaccaaaag cccctgggat gaaatacaaa
    11521 cactactcac ccgatacacg tgttctgatg gtcagagatg gcgattggtc aactgcagtt
    11581 caatgggcaa aaaataagaa gatccgtgca ggtgtcatag caagccccga aattgcggat
    11641 caagtgcgga cagatactgc agctgtttat atgtataacg acaactcagt agaagcggcg
    11701 gctaaaggat tgtttgcagg tctaagagga ttagatgaac caacacttgg attagatttg
    11761 atttttgtac aagtgtatcc agaaactgga ttggggaatg cttacatgaa tcgcttgaaa
    11821 aaagcagcag gacaaaatta ttttgaaaaa tgatcaattg gttattgtcg cattctttta
    11881 gtatgataca atgctatcaa gtaaatcttc tatcagtgaa cgaaaaacta agcgtaacta
    11941 atcgtaatag aagagatacg aatatttggc aatttgtttt tgatgggaaa aataaaattg
    12001 taggaaaata aaaaggagct gttgtttgtg gtagattaca aaacgtttga ccctgatctt
    12061 tgggctgcga tcgccaaaga agaagaaaga caagaacata atttggagct gattgcctct
    12121 gaaaactttg tctccgaagc agtgatggct gcacaaggaa gtatcttgac aaataaatac
    12181 gcagaaggtt atccagggca tcgctattat ggtgggtgtg aatttgtcga tatcgttgaa
    12241 aatttagcga ttgaccgtgc aaaagaatta ttcggagcga aatttgcgaa cgtccagcct
    12301 cactccggct ctcaagccaa cacggctgct tatctcgctt tggtagaacc aggggacacg
    12361 atcttaggaa tggatctttc cgcaggcgga catctaacac atggatcacc agtcaacttc
    12421 agtggcaaaa cctatcactt tgttgcttac ggtgttgatc cgacaacaga agttattgat
    12481 tataatgtgg tacgtatttt agctagaaaa catcaaccaa aattgatcgt agcaggtgcc
    12541 agtgcttacg gacgaacgat cgactttgcg aaattcagag aaatcgcaga tgaagtaggc
    12601 gcaaaactga tggtagatat ggcacatatc gcaggattag tagcagcagg acttcatcct
    12661 aatccagttc cttatgcaga tatcacaacg actaccactc ataaaacatt gcgtggccct
    12721 cgaggcggca tgattttgac aaacgatgaa gcattagcaa aaaaaataaa tagtgcggta
    12781 tttcctggta ttcaaggcgg ccctctagag catgtgattg cgggtaaagc agtagcattc
    12841 aaagaagcat tagatcctgc atttaaagaa tatagtgaac aaatcatcgc caatgcaaaa
    12901 gcaatggtca aagttttcaa tcaagcaatt ggaaccagag tcatttcagg ggcgacagat
    12961 aatcatctga tgttgatcga tgttcgcgag ttaggtataa atggaaaaga agcagagagc
    13021 attttggaca gtgtgaatat cactgtaaat aaaaactcga ttccttttga aacactaagt
    13081 ccattcaaaa caagcggtat tcgaatcggc acgccagcaa tcactactcg cgggttcaaa
    13141 gaagaagatg ctgtaaaagt ggctgaacta gttgtcaaag cattacaagc aaaagatgat
    13201 aacgctcaac tagacgaagt caaaacaggt gtacgcgaat taactgaaaa atttccgttg
    13261 cataaaaaat aaaaatttaa attccattag taaacagaaa agttcaatgt tgggcttttc
    13321 tgtttatttt ttgggaaaac ggattctttg acaatatcgg tgatgctctc tagtatatga
    13381 ggtgtaattt tagtcttcac actaaatctc agggaggaaa agtcatgact gatcgtatct
    13441 cgttagaaaa ggaagcagta gcattcagtg atgcaaatgc gcctcatccg cgtatctatg
    13501 aactagcacc ggaagaagga agagttttac tagaagaagt acaagaatca cctgtgaaca
    13561 aatattccgt cgatattgaa gacttgatgg tggatactgg cgaatgggga aaactcaata
    13621 ttcgtctcgt acgaccagaa gggaatatgg ataaattacc agttattttt tatattcatg
    13681 gagcaggctg ggtttttggc agtgctcaaa cccatgataa attgatcaga gaacttgcgg
    13741 ttcgtacgaa ttccgtcgtt gtctttccag aatatagtcg atcaccagaa gcaaaatatc
    13801 caacagcaat tgaacaaaat tatgctgtgt tgcaacagct gaataaatta gccaagtcaa
    13861 aaaatctgga tctcgagaat ctaatcgttg caggagattc agtaggtggt aacatggcta
    13921 cagtcatgac gatcttaaca aaagaacgaa agggcctccc aatatccaag caattgctgt
    13981 attatccagt cacaaacgct gattttgata cagattccta tcatgaattc ggagaaaact
    14041 attttttgac aagagaagga atgatgtggt tttgggacca atatacgacg aatgaagaag
    14101 agcgtgctga aatcacagct tcgcctttga gagcaaatat aaatgaacta aatgatcttc
    14161 cttcagcaat gattttaacg ggagaagcgg atgtattaag agatgaaggt gaggcttatg
    14221 cgcgcaaact tcgtgatgca ggggttcctg ttacacaagt acgcttccaa ggaatcatcc
    14281 atgattttgt catggtaaat gctatggatc agacaaaggc aacgcgtgca gcaatggcat
    14341 tatctacttc ttggatcaag aaaaaagaat aagctttgct tgtccgcagg aaaacttctt
    14401 ttcaaaaacg gattttctta ggaaaaatgg cgagtttgac tagtcaatca cttgattttg
    14461 ttttacaatt aaaaagaaac gacagaacaa aggagagctt aaaaaatggg caaatttcaa
    14521 gtgatcgatc atccattgat tcaacacaaa ctaactatta ttcgggacaa aaactgcgga
    14581 acaaaggttt ttcgtgaagt agtcgatgaa atcgctatgt tgatggcata tgaagtatca
    14641 cgggatatgc cattggaaga catcgtgatc gaaacaccga tcactgaaac aacacaaaaa
    14701 acgttgtctg gtaaaaaagt agcgattatt ccaatcttgc gcgcaggtat tggaatggtt
    14761 gacggtatct tggaattgat tccagctgct aaagtgggac atatcggtct ttatcgagat
    14821 gaagaaacat tggaaccaca tgaatatttc gtcaaacttc cagaagacat tgatgcacgt
    14881 cagttgtttg tagtagatcc aatgttggca acaggcggat cagcaatcat ggcaatcgat
    14941 gcattgaaag aacgtggcgc gtcgaacatt aaatttgttt gtttggtagc agcacctgag
    15001 ggagtaaaag ctttgcaaga agcgcatcct gatattgaca tctatacagc ttctctagat
    15061 gaaaaattga atgaacatgg ttatatcgtt cctggactag gggatgcggg tgaccgtttg
    15121 tttggtacaa aataagtaaa tacgaaaaag ggtgtgacac aacttttgtc acatcctttt
    15181 ttggtcattt ttaacgtttg atgcagaaca gctttttcac agctttcgtt tgcatataaa
    15241 aaaaccatcc caaaaatgca gagatggtca aattcaaatc ttttttagtt ctttgtagtt
    15301 aacgattact acacccttac tttgcgtcat caagttcgca ttttctgcag tttcatcaat
    15361 ctcaacaaca gcggaatttt tcaattgctt tgaaatcgtt ccagtttgcg acttgccgtg
    15421 aattgtgaac attacgtgag tattgatctt gaatttttca ccaatttccg atggtacgat
    15481 agttgtatca aattttccaa aagttgccat tttcataaaa cctgcctttc acatcaatta
    15541 taccacgttt tatgaaaaat atcatgaaat taaactaatt ttccatcgga ctctttacaa
    15601 tcagccaaat agagtatata atttcttttg gataaggcca gcttagctca gttggtagag
    15661 caacgcactc gtaacgcgta ggtcgtaggt tcgatcccta tagctggcat taaaagagaa
    15721 gacagatata tcaaggattt ttaatccatt gatacatctg tctttttgtt taaaggaaat
    15781 aaagtatgct ttcttagcaa tagagcatgt attatttcta taaaaattta ggagaataaa
    15841 acgactagca atatagctgt gaaatcaaat atcacatgaa ctgcccaact tgtaatgatc
    15901 gagttgcttt taatggcagc ttggttgaat aacaatcttg ccaccccttg tatcaaaagg
    15961 atgtgtgcta cagtgtgtaa aatatttcca ttatcataag tactgtaatg gataaatcca
    16021 aagatgattg ctgacaagaa actagcgaca ggaatgctga acttactaga aaaaatagcg
    16081 agaaaataca ctgagaacaa ttcttctcca agtatcatga taggcaaaat aataaataat
    16141 aacgggctga aagcctcatt tattggattg cctgttaaac cccatttcaa aatttgttgc
    16201 aaaaataccg agactgcggc actgattact acattgataa aaaaatattt ggctatattt
    16261 ttgacaggag cgacaggttt cgagaacatt tttttcgtat cttttttacc aaaaacaagt
    16321 gtaaatgcta taaatccagt gatagttaaa gaaaaaatgc taataatgga tggcgcaaat
    16381 agcaacccta acaaaccgag tacaacgaca atagtgccca atatcccttt tttaagttct
    16441 attttttttc ctaaaatgtt attcatgata ataactccta ctattcagtt tttgaagata
    16501 gagtcagtat acatgaagag ttaaaatagg caatgttttt ttatggatat ttgtattgct
    16561 aaaaatttat cttatatatt cattttgatt atactacttt tatttgtaaa aattttctag
    16621 caaaaccaag tgcttgcaac tgattaagcg tacaattttt tagatgttcc gagcgtactt
    16681 caatcatttc aaaggagttg ctacttaaat cgatattttt taaatcagta tcaaaaaagc
    16741 tagcattttc taaatcatta gtagaaaaca ttattttagt gagggaacag tctacaaaat
    16801 ctgcgcttga taagacagag tgctcaaagg tactttcttt tatgtttgaa ccagataaat
    16861 ttacatagtc cattttacaa ttctcgaata acgtgttccc aatataactt tccatcaatt
    16921 tagtacctgt taatttacaa ttgacaaatt tcacgcgatg caacatgctt tttgtcaata
    16981 tacagcctga aaaatcacag ttttcgaata tacagtcggt aatctccatt ctttgaaaat
    17041 cattggaagc aaaaaatgca tacttgaaaa tagatttgta aataattgga tggcagatta
    17101 tttggttttc gatgacctct ttttgtgaaa ggatattata cagttcaaaa tcttcgtttt
    17161 catagatatg aaaaaaggat cctttattca agcttgcttc attaacttta ggaaaaatca
    17221 tatttaatta cctccatttt cataaagtca tattaacaaa agctaaacca acttacatta
    17281 gcagaaaatg agataggttt tcgccttttt cgataacgat agtgtcgcta tctcttgaaa
    17341 cgttcttaga attgccctga gagacacaaa ttaggcgtaa ttctaataaa aatcttagaa
    17401 taaaaatttt tactgattta atttagaatg tttttaaaat aaaaatcgtt gccataacag
    17461 tgtattgaaa ggttttaaca atccagtaat gatttaaaaa aatctagatg tagcgtatac
    17521 tttgtttata gaatgtagtg ggaagaaata tatttttggg aggaaatcgt gatgtctaaa
    17581 agtgaagaaa tagaaaacat ggtactaaaa ttatatgatc tcgttttaaa tccagagatc
    17641 aaagaaaagg aacgtatact tttgatagac gcaaagacag gcttagaaaa aggtcagtat
    17701 tatcctaaag tcataaataa tttggaacgt agtttacgtc cgttagcaat caggggagaa
    17761 ttgtctaaac cagtatcacc gttttatatg gagatatcaa caataggaaa atttgaaaaa
    17821 gaattaggtc gaggaatggc ttcggcaccg attacttttg ggcatttata aaaacgagtt
    17881 attcatctca atgaattaaa aagtatagtc aatctcataa tgcaggctag gttcatttat
    17941 ttgaacagag tctgtatttt tttattctaa ataaagaaac agatgtttct ttatattgta
    18001 ttttatcctt taattaacac aaaaacagct agtataaact aataatgtta attaaaagtg
    18061 tattttatga aactatcgtt atttattaat gttgcatttt tgtaagttaa aaattggaaa
    18121 tatagattga aaaaatgaaa gcaataagta aaataaaatg aatatatgcg aaaaaataat
    18181 ttacattagg aaaaaccttg taaaaacagt tttttggcat atttattttt tataaatatt
    18241 tgtaaaataa ctatcaattt tttagttaaa agattggaaa tgagtggggg aggaattgaa
    18301 gaaaggattt ttgagagatg atatagtagg ttttattttt agttaaaata ggggagatag
    18361 aaaaaatgaa aaagtgtaga aatattattt tatcaatgtt atttattatt actaatataa
    18421 catcactgat tcctgttcat gtctatgcgg atgcaggcag agatatcagc agtaatgtca
    18481 cttcgttgac cgtggaccca acgaatatta cagatggagg aaacataaaa gtaaaattct
    18541 cgtttgacga aaaaaaacaa aatatccaac caggtgatta tctttggatc aattggccaa
    18601 gtgaaggaaa tattcgcggt gaaggattcc aaaaagaaat cccattaatg attgaaaata
    18661 aaaatgttgg aactttaacg gtcagaaaag attctgcgca ggttgtgttt aatgaaaata
    18721 ttaaaaacct agactcagta gaaggttggg ggcaatttga gatacaggcc agaaacgtaa
    18781 ccgataccgg tgaagaaaat acgggaccat tcaccgtgac gagcggtgat aaaacagcta
    18841 ctgtaaatgt gacaaagcca gcttctggtt cttcttctag cgttttttat tataaaacag
    18901 gagacatgct acctgaagat actaagcaca ttcgatggtt tttgaatatt aacaataacg
    18961 gcacttatgt tgaacaacca gttaaaatca gtgatgaaat ccaaagtgga caaagattag
    19021 atccaagtac gtttgaaatt aatcaaatac acttaggtga acagaaggtt tatagaggag
    19081 aagagggaat ccaacaattt ttacaagatt tccccagcgc tacatttaat ttttcagtaa
    19141 ctgataatta cattgaaata actataccaa aaaactttgt caatcttagg aaaataatgg
    19201 tgagttataa gacgatcata gaaaacccag aacaaataaa ttttgagaat cattcggaag
    19261 cttggtttaa agaatttaat aaacctgctg ttgatggaga aagtttcaat catacagtta
    19321 aaaatatttc agcttctggt ggagtcaacg gtacagttag aggcgaattg aagattttca
    19381 aatatatcaa tgacacagag attggtatcc caaatgtgac tttcgaatta agacgagcag
    19441 atgaacagcc tattcaagga cagtctagta tcctgttgac ttcgaatgaa cagggagaag
    19501 ctagtatcaa aggcctgcaa gtaggagact atgttgtaaa agaaaaagaa gcacccaatt
    19561 ggattgattt tgatccacta agttcaaatg aactcaaatt ctccataaac gaaaatgata
    19621 cagagggagt cagtttacct atttataaca agaaaaaggt tacgaacatc acagcaacta
    19681 aaatttggaa cggtggaacc actccaagac cgagtattta ttttaaatta ttcagagcaa
    19741 gtacaaacaa ttgggaacca gttcctgatg cagaaacaaa acgattagac aatggaataa
    19801 cttcagtgac ttgggaagat atccaacagt atgatgatag tggaaacgaa tatacgttta
    19861 aagtgcaaga agtagatcaa aacggaaatg attatgtccc ttcaggttat caaaaaattg
    19921 aaaacgggct agtcgttaca aatgagaata aagaagtcat ttcagtctca ggacaaaaaa
    19981 catgggaaga caatgagaac caagacggca aacgaccgac gacgatcaca gtaaatctat
    20041 tagccgacgg tcaaccgatc caacacaaag aagtaagtga aaaagatgat tggcgctatc
    20101 gtttcacaaa tctgccaaaa tacagagacg ggcaagaaat catctatact gtaacggaag
    20161 acaacgtgcc cgaatacagt acgacgattg acgggtataa catcaaaaac agttatacac
    20221 cggaaaaaac aaatatatct ataccaggta gccatataac accgtggaaa aattttccag
    20281 agaagacaga gagagagaaa attagaaatc tattctctca aaaattgcaa atatttgctc
    20341 atacaggaga atccagcgaa caaagaagca attatattag taagagagct gtacctaaac
    20401 agataacaaa taaatcaaaa agcattcttc ctaaaacaag tagtaaaaaa tctagttttg
    20461 ctgtaatcat tggtttattg atagtaacta tctgtgctgg gatattctta caaaaatata
    20521 aaaaagttta gttagaatat aatatttttt gttaaatatg actgaaatca aaagaataaa
    20581 attccgattt ataatcgaaa aaagaagcat ttttatatat gcttcttttt tcgtagaatc
    20641 aataaatatg gatttggcta actatggaag aatactcgta ttagttttca gcgttcatac
    20701 tagttgttac attgtttgat tggccaaaag aatttctgat atattttgtg ctaaataaag
    20761 aaaaagacgc ttgaattggg aaataagaaa actactctat cattacaaat tttcataaac
    20821 tggcagatgt tctaagtaaa caagtatctt ttcaaagtcg gaaaaatcca taatcaacgt
    20881 agtggtattg atatttggat gaaagcctac ggtatcttga cgatcaatag cagcatcgat
    20941 cacgacttgg atttttttct ctttgtcgtg catcaatgct aatggagtca ctgtacctgc
    21001 tggaacgcct aggaggtcag gaagctgttc ttcagaaaca aaagataagc gcttttcttt
    21061 taattgttca gctagttgtt ttaaatcggc gtgcttttca tcaggcaaga tgacaagata
    21121 gatttgtttt ccttttcttg atttcaataa tagatttttt acttgcggac caggtaggga
    21181 aaaagggaca tttttgactg acgtaatcgc aggatgatcg actttttgaa aagagatacc
    21241 cagttttttt agtagttcat aagcttcttg ttcggttgca cgactcatcg cgcatcaccc
    21301 tccttttttt attagtgtat cataaaaaag agttgacaaa tgaaaaataa tcatgtaaat
    21361 tacacgtaaa gttaaaacaa atgacatcga aaagaagagt agccgttagg tgtttttaga
    21421 gagtctctgg ttggtggaaa gaggcagcag ttaaccgtga aacacatctt ggagtcgatt
    21481 ttctgaagcg tatagtagga aaatccgggg agcccgttac agctgcggtc gttgctagat
    21541 gaccagataa ggctggcttt tccgtgagga gtcggtaaaa aaaggtggaa ccacgtgatt
    21601 aacgtccttt gatcttcgga tcaaaggact ttttgttttc atctgaacgg caacgactgt
    21661 gtgaggtttt ttctgcaagg aaaaaataaa cagaggtgga accacgtata atacgtcctc
    21721 ttggcatttg ccaagaggat ttttttattt taaaggagga aaagaagatg gagtatttga
    21781 ttgaagttat gccgcaatta ttagtaggag cactcacaac attgaaatta tttttattta
    21841 ccttgattgg ctcattacca ttagggattg ttttagcatt aggattgtct ttgcatttta
    21901 agccgctacg ctacttgctt caaacatatg tatgggttat gcggggaaca ccgctgttgt
    21961 tgcaactgat ttttattttt tatgggttgc cgacgattgg gatcgttttt gatcgtttcg
    22021 aagcagcact cattgccttt atcttaaact atgcagctta ttttgcagag atctttcgtg
    22081 gagggataca atcgattcct caaggtcaat atgaagcagc gcaagttttg caattaagtc
    22141 cctttcaaac ggtgacgaaa atcgtcatcc cacaagtgac aaagattgtt ttaccttctg
    22201 tagggaatga agttatcaac ttggtcaaag attcttcctt gatctatata ttaggtttag
    22261 gtgacgtaat gcgtgctggg aaaatcgcga tggaacgcga cgcgacttta ctgcctttgc
    22321 taggcgtggc aatcatctat cttacattga ctggtattct aacaatcata atgaaacaag
    22381 ttgaaggaaa attaaattat taccgctaac tgataggagg aagaaatatg attgaattga
    22441 agaaagtgaa caaagcattt ggtgaaaaaa aaataatcaa agatttgaat ctaatcattc
    22501 cagatgggaa aacattagct atcgtaggtc cttccggtgg cggtaaaacc acgcttttac
    22561 gtatcttggc tggcttagaa agttctgaca gcggagaatt ttatttagac ggtgtaccgt
    22621 tcaacccatt cgagcttaaa atgaaagaac aagttgtagg agtcgtattc caagacttcc
    22681 agctatttcc acatctgaat atttttgaaa acattacctt agcaccaaaa atggtattga
    22741 aacagacaaa agaagaatac accaaaaaag cagaagaatt agcggcttca ttagggatta
    22801 gtgatttatt gaatatctat ccttatcagc tttctggcgg acaaaaacag cgggtagcga
    22861 ttgccagagc attggctatg aatccacggg tattggctta tgatgaacca acaagtgctt
    22921 tagatcctga attacgccag caagtcgagc gtttgatcct atcattgaaa gaagatgggg
    22981 taacccaaat tattgtcacc catgatttag tatttgcaga aaatgtcggt gatcaattac
    23041 taaaagtttc cccaattcat taagaaagga gaagatagag atgaaaaaaa ccagttttct
    23101 attcgctttg atcgcaggtc ttcttctttt tgcaggctgt tcgaacaaaa aaacttcagc
    23161 agataattgg gcgactatca acgaagagaa aaaaatcgtt ataggtttag acgatacatt
    23221 tgttcctatg ggatttagag ataaagacgg gaagctcaca ggatttgata ttgatttagc
    23281 caaagcagtc tttgaacaat atgggattac ggtagacttt cagcccattg actggtcaat
    23341 gaaggaattt gaactgaaca atggaacgat cgatttgata tggaacggct attccaaaac
    23401 gccggcaaga gaaaagaaag tgcaatttac aaaaccttat atggaaaacg atcaagtgct
    23461 gatcacacct aaagaatcag gaatcacaaa ctttggacaa atgaataata agagattagg
    23521 tgcgcaaaat gggtcatctg gttatgatgt atttacgaaa caaccagaag tattaaaaga
    23581 gatagtcaaa aaccaagatg ctgttttgta tgatagtttt aatgaagcat tgatcgatct
    23641 gaaaagcaga cgggtcgatg gtctgctgat ggataaagta tacgcagact attatttgaa
    23701 acaaagaaac gaactagaag acttcaacat aacaaaaggt tcttatgaga gtgaggattt
    23761 tgcagttggt gcacgcaagt cagatagtac attagtgaaa aaaatcaatg aagccctaga
    23821 tcaactagag aaaacaggtg aattccaaaa aatatccgat aaatggtttg gcgaagatgt
    23881 tacgccgaga aattaacaaa taggggactg tgacaaaaga cgtgtcacag tccctttttc
    23941 cgaataaaca gtgttctcct gccaactcct tgtgactcgg agctgaatgg caggctcaca
    24001 acctcttggt aaacggtgtt caaaagccag tttttcggta ttaagccaaa tttatgcaaa
    24061 aatgtagaaa gccattttca caaaattttt cttactactc gaaactaagc gactttttca
    24121 caacctcctt tacataattt tattttgttg tggaaggggt ttcgtgttat tctaaaagag
    24181 gaacgattga aggttatagg aaaggaagag atgaatggaa cacaaagaac ttacctcatt
    24241 tccaaaagat tttctgtggg gctctgcttc tgcagcgtat caagtagaag gagcttggca
    24301 agaagatggg aaaggagaat cagtctggga tcgatttgta cggatacctg gaaagacatt
    24361 taaaggaacg aacggtgatt tggcagtaga ccactatcat cgttataaag aagatattgc
    24421 tttaatgaaa gaacaaggtc tgaaagctta ccgcttctct gtagcttgga cacggatttt
    24481 tcctaatgga cgaggagaag tcaatcaagc tgggctcgct ttttatgaga gattgatcga
    24541 cgaattgatt gaaaacgata ttgaacctat gttgacttta tatcattggg atcttccaca
    24601 agcattgcaa gatgaatata atggttggga atcacgtcag atcattgaag atttcactca
    24661 ttatgcagaa acattatttg aggcattccg cgggaaagtc cattactgga ttagtttgaa
    24721 tgaacaaaat atcttcactt cattaggtta tttgttagca gcacatccgc caggtgtgac
    24781 agacccgaaa cgaatgtatg aagttaacca tattgctaat ttagcaaatg catctgtcat
    24841 caataaattt cacgagttag aaatgcctgg aaaaatcgga ccaagctttg cgtatacgcc
    24901 aaattatcca attgacagta atcctgaaaa tgttctggct gctgaaaatg cagaagacct
    24961 gatggccaat tattggatgg atgtctatat gtggggaaaa tatccgattg ctgccatgag
    25021 gttcttagaa gaaaaaggat gggcaccaac gattgaagct ggcgatgcag aattgctaga
    25081 atctgctaaa ccagattttc ttgggatcaa ttactatcaa acggcgacga atgcattcaa
    25141 tccattaaac ggagttggtg ctggaaaaat gaatacgaca ggaaaaaaag gttcatcaga
    25201 agaaactgga gttcctggaa tgtataaaaa agttgagaat ccatttgtcg aacgaacaaa
    25261 ttgggactgg gagattgacc cagaaggatt aaggatcgga ctgcgtcgta tcacaagccg
    25321 ttaccgcatg ccggtactga ttacggaaaa tggcttagga gagtatgaca agttgacaga
    25381 agataaacaa atccatgacg actatcgaat caattactta caaagccacg tcaaagccat
    25441 caaagaagca atttcggatg gagcagaagt cctaggctat tgcacctggt cttatacaga
    25501 tttgcttagc tggctgaacg gttatcaaaa gcgatatgga tttgtatatg ttgatcaaga
    25561 cgaaacacaa gaaggatctt tggaacgata taagaaagac agttattact ggtaccaaaa
    25621 actgattgaa gaaaatggag agaaccttta gttcacatac ttaaaacaag aaggtacggc
    25681 tggatatggc cgtgcctttt cttgataaaa tcatttagaa attaagaaaa actgtaaaat
    25741 aagctgaaaa atgaaagaaa gcgtcagttc tttcaaacaa aactttagtt cccttacttt
    25801 tttttgtata atgaaacttg atgaaatgag ggataataaa tggcacaaaa gaaacggcct
    25861 actaaaaaaa ggaaaaagac gaaaaaaacg aaaaagcaaa aacagcagca ggaacaaatg
    25921 ctgacgattg gtgttgggtt tgccttgatt ttatttgctg tcttcggctt tttaaaatta
    25981 ggttttttag gaatattgat tgcaaacggc tttcggatca ttgcaggaaa tacttaccaa
    26041 atcctctgtc ttttattagc cgtattagga ttttggattg tcattaagaa tacagagttt
    26101 tcaattggta aaaaccgacg ctggtttggc ggcatactct tttatttcgg tatcttatta
    26161 ttgttacatg cccatttatt tggcaaactc catactgggg aaccaaatat catggggacg
    26221 acatgggatt tgttagccag tgatataaaa caaagtcaag tagacaataa cgttggtggt
    26281 gggatgattg gagcaatcct ttatcatttt acttacttct tgattgcaca gcctggaagt
    26341 tatttagcag cagtgctatt actggcagga ggagcattcc tgttcagtaa tctggaaggc
    26401 tatcagctgt taaatggtat ccaatcaatt ggagaacgag tacaggaatt attggaaggt
    26461 gatcctgcca agcaagctcg aaagcaagcg gcaaaggaag agagaatgaa acagcgcgca
    26521 gaagcgaaag aagcaaggcg cttagctgca aaagaagctg cagaaaaaga agctgcagaa
    26581 tatgagaaga aaaaagcggt gagccagcaa agggaaaata ctgctgatga atggcaggaa
    26641 ccagaaaata cagagccgga gcagctaagt tttgttccaa tcgacagttt tcaagaaaat
    26701 atccatcctg cgaatctaga gaaaccagta ccagatacac caaaacagac caatacagca
    26761 gaaggttttt cagatgagtt gccagaggat gacggtacct cattagaatt tgagattgaa
    26821 gcagaacagg aaaatcaaga ctatgaatta ccgacagttg atttgcttga ttctatacca
    26881 actgtggatc aaagtgatga gtataaaaaa attgaaaaaa atatcggcgt attagaacaa
    26941 actttccaaa gtttcggtgt cgatgccaag gtcgtcaaag ccagcttagg accatccgtc
    27001 acaaaattcg aagtccagcc ggctgtaggg gtaaaagtaa gtaaaattgt gaacttaaca
    27061 gatgatatcg cgcttgcttt agcggcgaaa gatgtccgga tggaagcacc gattccaggt
    27121 aaatcactga ttggtattga agtaccaaat ggaaagatca gtatggtttc ctttagagaa
    27181 atcatcgaag cacaaccaaa ccacccagat aaattactag aagtaccttt aggacgtgat
    27241 gtttctggac gggtacaaac ggctgatctt tcgaagatgc ctcacttact cgtggctggt
    27301 tcgactggta gtgggaagtc agtagcaatt aatgggatta tcacaagtat attaatgcgt
    27361 gctaagcccc atgaagtaaa actgatgatg atcgatccga aaatggttga attgaatatg
    27421 tacaacggca tacctcatct gttgacgccg gtcgtgacga accctagaaa agcagcgcaa
    27481 gccttacaaa aagtagtaca agaaatggaa gaacgatatg aaaaattcgc ggcaaccgga
    27541 gtaagaaata tttctggtta caatgaattt gttcaacaga aaaacttgga aaacggaacg
    27601 aaacatccaa ccttaccatt catcgtagtg atcgtagatg aattagctga tttgatgatg
    27661 gtagccagca atgaagttga agatgcgatt attcgtttag cgcaaatggc tcgggcagcg
    27721 gggattcata tgatcctagc tactcaacgt ccaagtgtgg atgttatcac aggaatcatc
    27781 aaagcaaatg taccttccag aatggcattt gcggtatcaa gcggtacaga ttctcggacg
    27841 atcattgatt ctaatggggc agaaaagctc ttagggcgag gagatatgct attcttgcca
    27901 atgggtgaga ataaaccgat ccgtgtgcaa ggagcattca tttctgacca cgaagtagaa
    27961 cgggtcgttc aatttgttac agatcagcaa gaagctcatt atgaagagaa aatgatgccg
    28021 acagatgaag ttgaaacgac aggtgctcca gaacagccac aagatgagct gtttgaagaa
    28081 gcaaaagcac ttgtcgttga aatgcaaacg gcaagtattt cccttctcca aagaagattt
    28141 cggatcggtt acaaccgagc agcacgttta gtagatgaac tggaagctca tggagttgtt
    28201 ggcccgtcag aaggaagcaa gcctcggaaa gtattcattg agcaggaaga aacatcagaa
    28261 acgttgccgg acgataatga catgtaaaac ttgtgtgatg aagggttgaa aaacgaataa
    28321 ccaataaaaa gacaaggcat gatgatacca aaagaaaaaa tggttttttt ccatcttttc
    28381 taatacggta tgatgtcttg tctttttagt ttttgtgaga ttaaagttct attcgattta
    28441 tttgtgaagt attgcattaa ggaaatgaat catgtatagt atgtagcgaa actttgagaa
    28501 aaagagggaa aatactttgg aaaaacagtc catttatggc ttgacgaatg aagaattaat
    28561 caattggttt atagaaaacg gcgagaaaaa attccgagct gcccaagttt gggaatggtt
    28621 gtatcaaaaa cgtgtaagta atttcacaga aatgacgaat ctatcgaaac aattgatcga
    28681 aaaattatcg gagcatttta tcatcaatcc tctaaaacag atggtcgtcc aagaagcttc
    28741 ggatggtaca gtaaaatatt tgtttgaact ccctgataaa aacatgattg agactgtact
    28801 gatgagacaa gaatatggct tgtcagtttg tgtgacgaca caagtaggat gtaatatcgg
    28861 ctgtacgttt tgtgcaagcg ggctgctcaa aaagaaccgt gatctgactg ctggagaaat
    28921 tgttgcacag atcatgatgg tccaacatta ttttgatgag cgcaatcttg gcgaacgcgt
    28981 ttcacatgtc gttgtaatgg ggatcggtga gccatttgat aattacgaca atgtaatgga
    29041 ctttttgcat atcatcaatg atgccaaagg attggcaatt ggtgctcggc acattacagt
    29101 ttccactagt ggattagcac acaaaatcaa ggaattcgct aataacggct tgcaagtcaa
    29161 tctggctatt tccttgcacg cgccgaataa tgaggtgcga acatcgatca tgcggatcaa
    29221 ccgaagtttc ccaattgaga aattgatgga agctgtggat gagtatttag agaaaacaaa
    29281 ccgtcgaatc acgtttgaat atatcatgtt gaatcaagta aatgatagac cagagcatgc
    29341 gcaacaatta gcagatctat taaaagataa gaaaaaatta gcatatgtca acttgattcc
    29401 atataatcca gtcagtgaac atgatcaata ttctcgcagt ccaaaagctg atgtattgag
    29461 attttatgat gtattgaaga aaaacggcgt aaactgtgtg atacgtaaag aacatggtac
    29521 agatattgat gcagcttgcg gacaattgcg aagcaagcaa atgaaaaaaa cagttgccaa
    29581 ataatcgtat cctactcgtt ttttcaatta ccataaaagg agcagttttc ttaattaagg
    29641 aactgttcaa cttaaataag agaaaagatt ctatagcgaa agctataaag ctttttttga
    29701 caagaaaaac cctcatcaag caaagaaatg tcctcaattt gatgacagcc tgcttgatgg
    29761 gggttttagc aattatttaa ctgattttct tatatccttg ctggctttct tgtgtagcat
    29821 gataagtttc tacgtcaaga atggcctgtt taaatttttc tcgggtgatt tcataaggca
    29881 catgtttaat atcatttgtt gccatggctt tatctaagat tgcttctaaa tcggtcgtga
    29941 cattgagatt catgtcggtt aacgatactg gaagttggtt ctttttcata aacacataga
    30001 ttttatcaaa caaatcgaac tgctgatcca tcatcaataa ggtcagtaca ccataactga
    30061 cagatgctcc gtgaaggtat ccctccattt tttctagaac agtcgtaccg taatagaatg
    30121 agtgtgccat agcagaatta tagttattgt taactaaaac agaaaccaat ccggtagtaa
    30181 caatgatatc cgaaacgact tgttcaattg catatgaggg acgatcgtcg gcactatctt
    30241 tcaatgcttg cgtaccataa gtcaagagac gatcaatgca catttttccg atttggattc
    30301 ctaatctatc cgtgtagcct agatcatcgc cacgagcaga aaaagtagat tcgacttctt
    30361 tggataaagc atcgccaata cctgcccata agtatttatc aggtgcttcg gcaataattg
    30421 ctgtatcaat gaaggtgtgt acaggtggtt ttgaaggaaa gaagagtccg tccattacgc
    30481 cttcttcgtt atagatgaca cataccgcag tgacgggcga acagttcgaa ccaatagtgg
    30541 gaaaggtgaa gactggttta gctagttttt caccaatgac ttttacagta tcgcaagcac
    30601 ggccaccacc gactgcaaac aggacgtctg ctttttggac actttcatgc tggatcaact
    30661 gttcaatatt tccataagtt gaattacccc cgtaccagag actggcgaca acctctattt
    30721 cctgtgtcaa agctactttt attttgtttt ctgcctttga aagtgcagtc ttccctccaa
    30781 tcagcactac ttttgtccca tattctttga cgattccatt tgctttttca tacgcatctg
    30841 ttccaatggt ataatttggt aagaaaacac tttgactcat attcatttcc ttctttcttc
    30901 gttgaaacgg gttaaaattt taaagagtga tcgatctgac tgcggctgta gatggagtag
    30961 aggtgaacct aagacaggat aagtgatgaa taaggtggca tgaacacctt gaaatcatca
    31021 ataagtatcc taaaaacgaa caagtacaaa aacattgaaa acgacaataa tgaatttttg
    31081 ttcctcttag tatttctacc gattcccttt gcttttttgt aattatctaa aaattctaaa
    31141 aattaagatt attatatgaa aacaggtttt atttgtcaat tcataattgg ttttttttaa
    31201 agcaaaagat aatctatatc atgatgaaca aacagagttt tttcctccaa ttgatggctt
    31261 tcctgatctt tcctattttg aataaagtgt ttctgtataa tttttttatt ttataagtaa
    31321 gataaataat gaaagaatag agatactgat tggtagctaa agatttttga gcgagaacat
    31381 ttcgtttttt caaaaggact gttagaataa gcaagaacaa gggggaagac gtatgataat
    31441 cagtgaattt gaccgtaata atccagtatt gaaagatcag ctttctgatt tactgagact
    31501 gacttggccg gaagaatatg gagacagctc ggcagaagaa gtagaagaaa tgatgaatcc
    31561 agaacgaatc gcggtagcag cggtagacca agatgagtta gtaggattta ttggtgcaat
    31621 ccctcaatac ggtatcacag gttgggaatt gcatccatta gttgtagaaa gctcccgacg
    31681 aaagaaccaa ataggtactc gattagtcaa ttacttagaa aaagaagtag cttccagagg
    31741 aggaatcacg atttatttag gtacggatga tttagaccat ggaacaacgt taagtcaaac
    31801 ggacctgtat gagcatacat ttgataaagt ggcttccatc cagaaccttc gtgaacatcc
    31861 gtatgaattc tatgaaaaat taggttataa aatcgtaggt gtcttaccaa atgcaaatgg
    31921 ctgggacaaa ccggatattt ggatggcaaa aacgattatt cctcgaccaa attctcaata
    31981 ataaaaagag gttgtgacag aagtaatcag cttcaagaaa taagaaggaa tttacgaaaa
    32041 ttacttcttg aatttttgtg aaattccaac ttatttccga agaagctact tttggaacac
    32101 cgtgtaccag aggttgtgaa aaagtcgctt agtttcgagt agtaagaaaa attttgtgaa
    32161 aatggctttc tacatttttg cataaatttg gcttaatacc gagaaactgg cttttgaaca
    32221 ccgtttattc agataaggga ctgtgacaag acttttgtca cagtttcttt ttgtttattc
    32281 ttttttatct ttgtatggca ataatagaca atataacgaa aattatttaa tggcttttgg
    32341 aagaccatgg aaaaccttgt acaaagctat tttttctgaa aaattccttg aaacctcacg
    32401 aaaaaatcat tattttatga aaaagacaaa aaaaagtgtt gattttttaa taattattca
    32461 ttaaactctt aaacaacttc agaaaatatt aattattctg aaaattccaa taaaggggta
    32521 cgtaaaatga aaaagaaatt tacatttggt ttggttgcgg tatgcggcct tgtacttgct
    32581 ggatgttatg gcggcagttc agccacaagc agtagttcag caaaaagcgg ttcagcagat
    32641 ggaggaggcg tatttaactt agtcgtgcct caagaaatgc ctacagctga cttatcagtt
    32701 gcaacagata caatcagttt tacagcattg aataacgttt atgaaggaat ttaccgtctt
    32761 gatgaagaca gcaaaccaca gccggcagga gctagcgagt tggcagaagt cagtgaagac
    32821 ggattaactt acaaaatcaa attacgagaa gacgcaaaat ggtcaaatgg tgatcctgtt
    32881 acagcagcgg attacgttta tggctggcaa cgaacagtag acccagctac agcttctgaa
    32941 tatgcttacc tgtatgcgcc agttgaaaat gcagaagaca ttacagctgg aaagaaagat
    33001 aaatcagaac tagggatcaa agcagttggt gactatgaat tagaaatcaa attgacgaaa
    33061 caaacaccat atttccaata tctgcttgct ttcccatcat ttttcccaca aaaacaatcc
    33121 gtagtggaag aaaatgggga tgcctatgca tctgcaagtg ataaagctgt ttataatgga
    33181 ccattcacat tagaagattt tgatggacca ggaacagata cagaatggac ttataagaaa
    33241 aatgatcatt actgggacaa agatacagta aaactttctg aaatcaaagt cagtgtagta
    33301 aaagaatctt ctactgcatt gaacttattc aaagatggcc aagcagatga cgtgatcttg
    33361 tctggtgagt tagcacagca aaacgcaaac gatccagctt atacttctgt taaagaagcg
    33421 cggacaagct atatcgaatt caatcaacgt gaaaagaatt caccattcaa caatgtgaac
    33481 ctaagaaaag ctatttctta ttctatcgat cgtgaagctt tagtaaaaca agtactaggt
    33541 gacggatcag ttgtctctac aggattgatc ccatcagata tggtaaaaag tccaacaacg
    33601 aacgaagact ttgcaaaaga agctggaaaa ttagtttctt atgacaaaga taaagcaaaa
    33661 gaatattggg aaaaagcgaa aaaagaattg ggcgttgatt ctttagaatt tgatttgatg
    33721 gcttctgatg atgattcatc gaaaaaagta atcgaatatg ttcaaaactc aatccaagaa
    33781 aacttggatg gcgtaacagt caaaccaaca cctgttccat tctctgtacg tcttgaccgc
    33841 tcaacttcgg gtgattttga cgcagtacta ggcggatggg ctgctgacta tgcagaccca
    33901 agcagcttta ctgatttgtt tgtcacaggt aattcataca accgtggtcg ctggagcaat
    33961 gcagaatatg acgaagcagt taaagcagct tcatcaacag acgctggcga tgaacaagcc
    34021 cgttgggatg atttccaaaa agcaatcaag atcatctctg atgatatggg tgtcgttccg
    34081 gtgtaccaaa aagcagaagg tcacctagtg aatgaaaaaa tcaaaggtat cgttcaccat
    34141 gcggcaggcg cttcatggga ttacaaatgg acatacgttg aagaataatc gttaataccg
    34201 tgagcatgag aaaaaacgag gctgcggcaa atgtcgcaac ctcgttctca tattcactta
    34261 tcctaacaaa gaaaaaagca tgaaaatagc agaaagagca attagtattc cggcaatgat
    34321 cagccaaaag ctgtacatac cgtagctggc agacgagagc gaggaaaatt ctggtttttt
    34381 ctttcggttc cttgttcgtg caagatggac cgatcgctga aaatgatcga agaaacccga
    34441 agaaaagacc cataaaaaac cgccgataat cagaaacggc aatgaccata agaatagatc
    34501 attagataat tgaatgagtg taaaggaatg gttgatgaga ttttttatta aaataaccag
    34561 aatcagtaga aaagctactg cgtaggggat agattttttt ttcatttgat tgctccttta
    34621 tttttggttc attatctaat aatgtagcga aacatctgtc agaagtcaaa agctaggggg
    34681 aaacattagt gaatagttat atcaaatatg tattaaaacg tgtctttttc atgatcatca
    34741 cgctttggtt aattgcaaca atcacctttt tcttgatgca attgctgccg ggcacgccat
    34801 atacgaatca ggaacgtttg agtcctgaaa caatcgagat gctaaataaa caagtcggtt
    34861 tggataaacc agttatcgta caatatggga tttatctttc taatttgctt caaggagatt
    34921 ttggaatttc cttccaattt aaaaaccagc cagtcgcaca tttgttagct ggaagaatcg
    34981 gaccatcctt gcagttaggg ttacaggcaa ttatctttgg aacagtccta gggacgattt
    35041 taggaacgat ctctgccatg aagcaaaata catgggcaga tacatcttct acactcgtag
    35101 cgatattagg tcgttccatt ccaaactttg tatttgctgt tttattacaa tatatctttg
    35161 caatcaaatt acaagttttg ccaatcgcaa aatgggatgg ctttgtgtac acaatcttac
    35221 caacaattgc gttggccatg tcgccgcttg ctgactctgc tcggtttatc cgtacggaaa
    35281 tggtggaagt actgcatagt gattatgtgg aattagcaaa agcaaaagga ttgagccgtt
    35341 gggaaatcgc ctttaaacat ggtcttcgaa atagtttgat tccattgatg actttattag
    35401 gaccgttagc tgtagcattg atgaccggat cactggtggt agaaaatatc tttgctattc
    35461 ctggtatcgg ggaacaattc gttaagtcaa tcacaacaaa tgattatcct acgatcatgg
    35521 ctgtaacgat cctttactca tttatgctga tttttgttat tttgatcgtg gatctattgt
    35581 acggtctagt tgatccaaga attcgtgttt cagaagggag ccgaggataa atggaaatga
    35641 taccaaagcg ttatgaaaca gttgcagata tccctgcgga tgaatttctt ccattacaaa
    35701 aaaataccga agaagaacgt gaacagatta ctgcaccttc tttgaatttt atccaagatt
    35761 catggcgccg tttaaagaaa aacaaagctg ccgttatttc aatggtttta ctattggtca
    35821 tcattttgat ctctgtgatc acaatctttg tttctcctca tgatccaact gcccaaaacg
    35881 tggcttatat caatttgcct cctcgtattc cgggaatcaa tatcgatgga ttgaatggaa
    35941 aagcaatggt tggtggtgaa cttgttgata aatatgctca agcaaacgtc ccttcaaacg
    36001 taaatttctt tttaggaaca gacggtttgg gacgtgatgt attaagccgc ttatttatgg
    36061 gaatgagaat ctcgttgctg atcgcattta ttgctgcatt actagatgta acgattggtg
    36121 tagcttacgg gttggtttct ggtttgttag gcggacgtgt cgataacgtg atgcaacgtt
    36181 ttttggaaat cttatcagga attccaaacc tcgttgtcat gattttgatg ttggtcgttt
    36241 ttgaaccagg aattttttca atcgtggctg ctatggccat cacaaactgg ataccaatgg
    36301 cacgtatcgt tcgtgcacaa acaatgaaat taaaagatca agaatatgtt ttagctggat
    36361 tgacattagg tgaatcaaga atgaaaattg cattcaaaca tattttgccg aatatctcta
    36421 gtgtcattat tattcaaatg atgtttagta ttccatctgc tattttcttc gaagcctttt
    36481 taagctttat cggtttaggt cttacgcctc cgtcagcttc attaggaacg atgttgagcg
    36541 aagggtacaa gacattcctg tatctgcctt atctattatg gattccggca gtaactttat
    36601 cggttatcat gattggcttt aacttacttg ctgatggatt gcgtgatgcc tttgatccta
    36661 aaatgaaaga gtgaagacga tgacgaaaat tttagaagtg aaagacttag aaatctcttt
    36721 tgatacgtat gctggaaagg tacgagcgat tcgcggtgtc aattttcatt tgaataaagg
    36781 agaaacattg gcgatcgttg gggaatctgg aagtggaaaa tcagtgacga ccagaagcat
    36841 catgcgcttg ctgtcaagca acgccaatat agatgctggt caaatcctct ttaaaggtaa
    36901 cgatatcgtt ggaaaatcag aaagagagat gcaaaaaatc cgtggtaaag aaatagcgat
    36961 gattttccaa gatccaatga cctctttaga tccgacgatg cccattggga agcaagtcgc
    37021 tgagtccctt agaaagcata ataaagtttc aaaaaaagag ggacaaaaag ctgcattaga
    37081 attgcttaaa ttagttggaa tacccgaagc tgagaaacgt atcaacagtt atccgcatca
    37141 gttctcagga ggtcagcgtc aacggatcgt gatcgcgatt gcactggtat gttatccgga
    37201 aatactgatt gctgatgaac ctacaacagc gcttgatgtg actattcaag cacagatttt
    37261 ggagctgctg aaagaaattc agacaaaaat cgatacatca attatcttta tcactcatga
    37321 ccttggtgta gtagcgaatg tcgctgatcg tgtcgctgtc atgtatggag gaagaatcgt
    37381 tgaagttgga acatcggaag aaattttcta caacccgcaa catccctata cttggggact
    37441 gcttggttca atgccgacat tagatagtgc gaacgatcga ttgtatgcta ttcctggttc
    37501 tccaccggat ttattgaacc cgccaaaagg agacgcattc tatccaagaa atgaattcgc
    37561 gatgaaaatc gatgcagaac aagaaccacc attttttgaa ctatcaaaaa cacacaaggc
    37621 agcaacttgg ctacttgctc cgcaggcacc caaagtgaca ccgccagaag aaatccaacg
    37681 tcgctgggct atctttaaag agaaacaaaa acatacttac ggtcaaggag gaattgctga
    37741 tgccaaataa actacttgaa gttaaaggat tgaaacagta tttcaatgta ggaaaaaaga
    37801 atgaagtaca tgctgtaaat gacatcagct ttcacattta tgaaggagaa acattcggtt
    37861 tagttggaga atctggaagc ggaaaatcca ctactggccg tacgatcatt cgcttgaatg
    37921 aacctactga tggtgagata ttattcgacg gtcaagatat aacgaagatc aaagataaaa
    37981 aaggtttgac gaaattccgg catgatgttc agatgatctt tcaagatcca tacgcttcgt
    38041 tgaatcctcg tatgaaagtc agagatatca ttgccgaagg aattgatgtt aatggactag
    38101 ctaaatcatc tgaagagcgt gcaaaaaaag tcgatgatct attgagaact gttggattga
    38161 atccaagcca cggtactcgt tatcctcatg aattttcagg tgggcaacgc cagcgtattg
    38221 gtattgcacg agcattggca gtaaaaccgc gttttatcat ttgtgatgaa ccaatttctg
    38281 cactagatgt gtcgatccaa gcccaagtgg tcaatttgtt gcaagatctc caaaaagaac
    38341 atcaattgac ctatctattt attgcacatg atttgtcgat ggttaaacat attagtgacc
    38401 gaatcggtgt aatgcataac ggcttgttat tagagatggg aacaagtgat gaaatctata
    38461 atcacggtgt tcatccttat acagaaagtt tgttatctgc tattcctcta ccagatccag
    38521 accatgagag aaaacgcaga agaatcaaat atcaacctga accagatgac ggacaagtac
    38581 gtcaacttcg tgaaatcgca ccagaacatt ttgtctatgc aactgagcag gaagtcccat
    38641 attacgcaaa aaaactaaaa cgacaaaagg aatctcttct ggttgctaac taggagggac
    38701 atagatgcta aaagctttta aattccgtat gtatccgaca gaagaacaaa aacagcaatt
    38761 gattcgtact tttggatgtg ctcgatttac ctataaccat ttgctgaaaa agcggcagaa
    38821 aagttggcaa caaacaggag tagccaattt ttcgctcaca cccgctacat taaaaaaaga
    38881 atacccattc ttaaaagaag tagacagtct tgctttagca aatgcacagc ttaatttgga
    38941 tcgggctttt cgcaattatt tcaagggacg tgccagcttc ccaaagctta aaacgaaaaa
    39001 aagtatgtgg caatcttata cgaccaacaa ccaaacccgt acgatctatc tggaaaatgg
    39061 ctacttaaag ttaccaaaac aaaaagaact aatcaagata aatcagcatc ggccagttga
    39121 aggatcgatt cgctccgcta cgatttctgc tcgatataat gaagaatttt atgtcgcact
    39181 actttgtgat gtttcgccag taaaaaaaga atctttagct aaatggatcg ggatcgccta
    39241 tcatccgaag acattgatcc aaacatctcg acctctagaa gtaactttac caaaatttca
    39301 ccagacagaa gaaaagctgc aacatgcaca gcggaaattg aatgtgaaag tccgctccgc
    39361 tcaccataga aagatcaggt tagatcaggc aagcaattat cagaaacaaa agagaaaagt
    39421 aatggatctt tatctgaaac aaaagaacca gcgagaagat tatcttgaac aattatctgg
    39481 gaaattggtc aaacaatatg actacttatt tgtagaatct tttccaaaag aagaggcaca
    39541 tgctgatttt tctattcacg actggcataa attaataaca aaattgcgtt ataagtccca
    39601 atggtataat aaaaaatttc ttttgatcaa taccgacgga gcagaagaaa gcaattccgt
    39661 aagaaagagc caagtagtag aaaaaatggg cagacattcg gttatcaagg gataaaaaat
    39721 gaatgaaact gataggagcg ttagggttag ccttgttaat aaaaagtctt aatgactttt
    39781 gtttctagga atttttcttt tgaagaaaag ctcactaatt atgacaaacc aataaaacaa
    39841 tagcagaaaa agttcgtacg agctttttct gctattgtta attttttatt cagaaagttt
    39901 acgaatacat caaaattctg aaacaaaaaa cgtaactcac aaagagttgt ttttgcgttt
    39961 tttcttgaat gattaggtct gaatcttttg ctcacaacct tattcatggt gccccggctt
    40021 gagctgatag atttttgaag gacggccgat tcctacagga cgttcaccga tctcatcgaa
    40081 atattggagc atagctttct taaaattgga atgatcgatc gttttataat cgatccctaa
    40141 gaatttagca aatacttttc gagcttccgt aatcgtgaaa tctttaccta aaacttgtag
    40201 aacttgcggc tcgtgttcca ttttattgac tacacggttg aatgctttca agatgatttg
    40261 actatggtca aaagccaaag tatctttgcc agaagactct ccagtgacta aatcaagcga
    40321 gatagccact tctccgctag ataaatggat cttgttacta tgacgttcta gtgtgaacca
    40381 gcgtacttcc ttggcatcat ctccggcgat tagcggttct tctccaataa aggctaagta
    40441 gctgactgtg acgacccagc ctcgcggatc tcgattaggc gtactgaatg tatgcagttg
    40501 ctcaatattt tcttttgaaa taaccacacc agtttcttcc tttgtttctc ttaagacgct
    40561 ttctccagtt gactcatcct tttggacaaa gccaccaggc aatgcccatg aatttcgata
    40621 aggatgccct tttctttgga tcaacaaaac tttcagctga tcttcttctt tgttatagca
    40681 catcagtacg atatcgacag tcaaagaggg cttgtcatat tctggacgtt cctgtttttg
    40741 ataccagtta agaaattctt cttcacttgc tttatgttca taatataatt tttcttcttc
    40801 tttagaagca aaacggttca tctgaccacc tccattgaca gtaaaagtac tttttacctt
    40861 attgtagcag actctgaaaa aaaaccaagg atttacttga aaaatctagg ttatcattta
    40921 aatatgaaaa ataaatggaa gtatgagatt gaataaaaag aaaagcagat aaaacggcaa
    40981 tactttatac cgctcttcac gaatggcaaa gaagccacaa ataacgatat atacgtcaat
    41041 gataaaacgc aaaatccaag ctgctgtcat aaaactgttc aaatgcccat ggaggttaaa
    41101 ataaccatac atacgaatat aaaaatagct gaatattaaa tgtgctaatg aaagaaaagc
    41161 aatactaagt gtaaaaaaaa gatgtttctt ctgcatgatt gttccagtcc cttactaaga
    41221 tagatagtct ttattatacc acgtgtgagg ggagaaataa aaagccgttt tttagtagat
    41281 atgaaacaaa acaaaaaccc gcatttattc aacctattca tccttttaaa ggatagattg
    41341 aacgtagata gaagtcgttt atccagtctt tttcattttg aaaaaaagct aacagcatgc
    41401 tttttttatg gtatactagc aaggaaacga attcgcatca tgcgataaag gaggaagagc
    41461 cccgtggcag aaaaggaaac tttttatatc actacgccaa tctattatcc aagcggcaaa
    41521 cttcatatcg gcaactcgta tactacgatt gcatgtgacg caattgctcg ttataaacgg
    41581 ttgatgggct ttgatgtgtt ttatctcact ggagtggatg aacatggtca aaaaatcgaa
    41641 acaaaagcag aagaactagg tgtaaaaccg caagaatatg tagataaaat ggcggctgat
    41701 gtcaagaaat tatggaaaac gcttgatatc agttatgata aattcattcg cacgacagat
    41761 gattaccata aagcagctgt tcaaaaaata tttgatcgtt tattagaaca gggagatatt
    41821 tacttaggtg aatatgaagg ctggtactct gtttctgacg aagaattctt tacagaaaca
    41881 caacttgcag aagtgtacaa agatgacgaa ggtaacgtga tcggtggtaa agcgccaagt
    41941 ggacacgaag tagaattggt aaaagaagaa tcatacttct tccgcatgag caaatacgca
    42001 gaccgtctat tggaatacta tgaagaacat cccgaattca tccagccaga atctcgtaaa
    42061 aacgaaatga tcaacaactt tatcaaacca ggattagagg atcttgcagt ttcacgaaca
    42121 acttttactt ggggagtacc agtcaagagt gatccgaaac atgtggtgta tgtatggatc
    42181 gatgcattat ccaattatat tactgcacta ggatatggct ccgaagatga aagtctattc
    42241 gaaaaatact ggcctgcaga tgttcagatg gtcggtaaag aaatcgttcg ctttcatacg
    42301 atctattggc caatcatgct gatggccctt gatttgcctc tacctaaaaa agtatttggg
    42361 catggctggc tattgatgaa agacggaaaa atgtctaaat caaaaggaaa tgtcgtttat
    42421 cctgaaatgc ttgtggaacg ttatggttta gatgcactcc gttattattt gcttcgtgct
    42481 gttccgtttg ggtcagatgg tgtctttacg ccagaagatt ttgtttcccg tgtcaattat
    42541 gatctggcaa atgatctagg gaacttattg aatcgaacga ttgctatgat caacaaatat
    42601 tgtgatggac tcgttcctga ctatgcctca cttgtcactc catttgatag tgaactgtct
    42661 acgacggctg ctaacgttgt cggacgttac catgatgcaa tggaaaaaat ggaattcaat
    42721 acagcattgg ctgaaatctg ggtgctgatt tctcgtgcaa acaaatacat tgatgaaaca
    42781 gaaccatggg tattagcaaa agacgaagaa aagaaagctg aattgaatag tgtcatgatc
    42841 catttagctg aatctttgcg tatcgcagcg atattacttc agccaatcat gacagaaacg
    42901 ccagagaaga tcttcaatca actaggattg gactctgaaa caatgaatct tgaaggatta
    42961 cactttggcg aatttccttc aggaacaaaa gtagttgcaa aaggtacacc aatcttccca
    43021 cgtttagata tggaagaaga agttgctttt attcaagaaa aaatgtctga aggtactcaa
    43081 acaaacgaag atacagtcaa atgggatcca gaagaaacag aacttgtttc aacgaaagaa
    43141 aaacaaatca aatttgatgt atttgaaaaa gtagaactaa aagtagcaga agtcatcaac
    43201 tgtcaaaaag tagaaggggc agataagttg ctgcaattcc gactagatgc tggagacagc
    43261 caagaccgtc aaatcttgtc aggaatcgct gaattttatc ctgatccaag cgaattgatc
    43321 gggaaaaaag tcgtcattgt agcaaatctg aaaccacgaa agatgcgtgg acaaatcagt
    43381 caaggaatga tcctttctgc agaagcacca gatggctctt tacaagtaat cgaagcacca
    43441 aaatccatgc caaatggctc agaaatcgca tagaaattca aagggggtat gacactagtt
    43501 gtgtcatacc ccctttttcc gaaatttgag aagcaatttt cgtaaattcc ttcttattac
    43561 ttgaagccaa tcatataata cagaaacaga gaactatcca aaataaatcc tagaaaaaga
    43621 agtacgagct tcgctgattt ttgttaattt agaataatac taataggaat cgtaaaaaca
    43681 gaaaaaaagc ataatgataa agggtcgggc agattttaat tgattcatct ggtactcttt
    43741 tttattgtcc ttacattcat aaagtttgaa tgcaatgact ttattacatc tatatttata
    43801 tctaacagta gcgttgatgt gttaattata agttctatca ctttatgttc aattagtttg
    43861 tgctcttata tgtgtgattg aaaatataga taaaaaaaca atcatcggct ttgacttcga
    43921 tgattgtttt ctttattttg taaaaatcct atcacttgat tttatggtaa ccttttattt
    43981 ttgtcttcaa acggcttggt aagagagcag taagcagtgc aaatgggatc gaaaagacat
    44041 accagaaaat cgtacgtccg ataccataat gttgatagag ctttgtcaac atcacgtgta
    44101 acaagatcaa ccctaaaagc aaggagccag ctataaacca atgattatcc caatgcatga
    44161 cttcactaag tgccatcact ccaaaaggat agaaataaaa atagatcccg actaaggtca
    44221 tccgccagtt ctttgtaaat gttccgatat tcaataaaaa gaaaatcgct gaaagcaaaa
    44281 taccgatagg cggaaaaagc ccaaccaaaa aggaatacaa catcccccac aagatcatca
    44341 caggaccttt gatcaatgca acgattgcga tgaacaaagt cagcaatatt agtttttgtg
    44401 ataacgttgc aacagtcatt aatccaaata aaattaatgt gaaccaatgc caatgggact
    44461 gctgttgttc tttacgggaa aaatcgaccc ggttggataa ataatctgct aatttcggat
    44521 aagaacgctt aaaatccata aactgttcct ccttcgtgga aaaggtaggt ttagtatacg
    44581 aaaaataaaa aagaaataca tccgtcttaa gagggagttt ttcactgaaa gtggagaaaa
    44641 aagaatggta aattaaaata ttctcagtta tactgaaaat tataccaaat ttcaaagaag
    44701 aaagaggatg ggaatgaaag gcaaactaaa acgagaaatc aatctgtttg gcgcattagc
    44761 taccgttatg ggaaccgtga tcggtgcagg cgtcttcttc aaaactgctg ctgttactgc
    44821 tagtactcag tctacaagtt tgacattgct agcttggctt ttgggtggtt tcttaacgat
    44881 ctgtgctgga ttgacagtgg ctgaattagc tacagcaatc ccggaaactg gtggagctgt
    44941 aaaatatatt gaagctgcgt atggaaaatt gcccagcttt ttattaggat gggcgcaaag
    45001 cttgatttac tttcctgcta atattgctgc attatcgatt atctttgcga cacaattgac
    45061 gaacttatta caattatcta ccgattatct tttgttgatt gcagtgatca ccgctgtttc
    45121 tgtgacaggg ttgaatttgt tagggacaaa agtcggtgct tctgtacaat cagtgacgtt
    45181 gattgttaaa ttaataccaa ttgctgtgat tgtcatatgg ggattattga ccccaggaca
    45241 aggaactgtc cagttatttc caatcgaagc tggaaaagat gttacttttg tcgaaggatt
    45301 gagcagtgcg ttgttagcaa cgttgtttgc ttatgacggc tggttaggtg tcggtgcaat
    45361 ggcaggggaa atgaaacggc cggaaaaaga tttgcctaaa gcaattattc ttggtttgag
    45421 ttttgtaaca gtcgtttatc tattgatcaa ttttgttttt ttgaaaactt tgccgattga
    45481 tcatcttgcc ggtaatttga atgcagcttc tgaagcatca gacgtcattt ttggaggaat
    45541 cggtggaaag ctggtcacta ttgggatctt gatctcggta tacggtgcat tgaacggtta
    45601 tacactaact gggatccgcg tgccttatgc gatggcttta gaagacgagc tacctttcag
    45661 taaacagctg acaaagcttt caaagaagtt tacggttcct tatgttcctg cggttttcca
    45721 gttagcagta gcttgtatta tgatgagcct tggttctttc gactttttaa cagacatgtt
    45781 gatttttgtg atgtggctat tcagtttact gatttttatc ggtgtcttta ttttaagaaa
    45841 aaaagcgccg gaattgccac gtccatataa agtaccactt tatccaatcg ttccgattat
    45901 tgcgattctc ggtgctattt tcattttagg tatgacgatg atgacgcaaa cgaaattagc
    45961 attgatcggt ataggtgtta ccttgatagg tatcccagtc tattatcaaa aaaagaaaaa
    46021 acgctcagaa gagtaaaata tttcaacaac agacagaaaa agtacgaact aggtcctcta
    46081 gatcttcgtg ctttttctat ttcaataaaa caagttcttc tattttgatt tttgctactt
    46141 ctgcaagtag tgcttatgtg ctaaagtaag aatgaaaagg agagataaac atgatatttg
    46201 attctcatac ccatttaaat gctgaacagt tcaatgaaga tattccagaa acgattcagc
    46261 gagcacaaga aatgggggta acgaaaatgg cggtcgtggg cttcgatacg ccaacgattg
    46321 aaaagtcttt gcaattaagc catgactatc caaatatata cagtattatc ggctggcatc
    46381 cgacagaggc tggcagttat acgaaagaaa tcgaaaataa attacaagaa caattgactt
    46441 taccaaaggt tgtagcatta ggggaaattg gcttggatta tcattggatg gaagacccga
    46501 aagaagtcca agataaagta tttcgcagac agattgctat cgcaaaagaa atgaacctac
    46561 caatcagtat tcatactaga gaagcacttg aagacacgta tcaaatccta aaagaagaag
    46621 atgttcgaga tatcggtgga atcatgcata gtttcagtgg tgattatgaa tgggcaaaac
    46681 gatttcttga cttagggatg catatttcat ttagcggtgt cgtcactttc aaaaaagcat
    46741 tagacgtcca agaggctgca gcaaatgtac caatcgaacg attacttgtg gaaacagatg
    46801 ccccttatct ggcaccagtt ccttttagag gaaagcgaaa tgaaccaggc tatactcgtt
    46861 atacagtaga aaagattgct gaacttcgga atcttccgac agaagaagtg gctgcccaaa
    46921 catggacaaa tgcgcaccga ttatttggtc taagcgaaca tggataagat gaagatccaa
    46981 gagattatag tcgttgaagg aaaagacgat acaagaaggc tgcgggaagt agttgatgca
    47041 gatacgatag aaacaatagg gtctgcaatc aatgaagaga tcctgatgca aattgaacat
    47101 gcccaagaga ctcgtggagt gatcgttttt accgatcctg atttttcagg agaaaaaata
    47161 agaaaaatca ttatggaagc tgttcctcag gcaaaacatg cttttttgcc gcgcacacaa
    47221 gctaaaccaa agaaaaaggg aagccttggt gtcgagcatg caagtgatgc tgctatttta
    47281 gaagcattga aaaaggtcgt gacgccagac atttcccaaa cggctgtttc tgaaatcact
    47341 agacaagacc ttttagacta tggtttaata gctggggcac aagcaaaaga aaaacgagaa
    47401 aaactaggtg acgagttgcg catcggttac acgaacggca aacaattgga aaaacgtttg
    47461 aagatgtttc gtattacgcc gaaagaactc gcccaagcaa tgaaaatagt ggaggaacaa
    47521 catgagtgaa tatcgtgaaa ttgcgacacc ctctagaaca aaagagattt tattgaaaca
    47581 tggtttttca tttaaaaaaa gtttaggaca aaattttctg actgaaccaa atattttaag
    47641 gaaaatcgta gaaactgcgc aaatagatga acatacgaac gtgatcgaag ttggaccagg
    47701 aatcggtgca ttgacggaac aattagccaa gcatgcaaaa caagtcgtag catttgagat
    47761 cgatgatcgt ttgatccctg tattggctga tacgatgcaa ccctatgaca atgtgactat
    47821 tgtacatcaa gatattttaa agaccgattt gtcaacagct gttagagaaa catttcatga
    47881 ggagcttccg ttaaaagtcg tagcgaattt accttactat attacgacac cgatcatgat
    47941 gcattttctt gaatcagatt tggttgtgga tgaactagtc gtcatgatgc aaaaagaagt
    48001 agctgatcgt atctctgctg aaccaggaac gaaagcttat ggttcattat cgattgctgt
    48061 tcaatattat atggaagcca gtttagcatt catcgtacca aaaacagtat ttgtccctca
    48121 gccaaatgta gattcagcga ttttgaaact gacaagaaga gatataccgg cagtcgaagt
    48181 gacagacgaa aaagcatttt tccgattgac aaaagcggca tttcagcaaa gaagaaaaac
    48241 gctttggaat aacttgcagc attcgtatgg caaagatgac cagacaaaag catggttagc
    48301 aaaaagcttg gaaacagctg gaatcgatcc aaaacgtcgt ggggagactt tgtcattaca
    48361 agaattcgcc gcattaagca atgcgatgtc agaaaatatg cagtaaaaaa agaggttgtg
    48421 acagaagttg tgaaaaagct gtcctgcatc aagtaataag aacagccaaa caaaaatagt
    48481 tcctcatgtt tttcgtttgt ttgggcttat taccgcagat gcaagctttt gaacaccgtt
    48541 taagaaagag gttgtgggcc tgccgtttaa ctctaagtca caaggaacaa tttcaaaaaa
    48601 cagcttctca tgtttttgag ttagttggtc ttattacttg atgcaagctt ttgaccacta
    48661 ttatgccgaa caaggagatg tgacacaaat tttgtcacat ctcctatttt tgtttcttga
    48721 tcaaaaaatt cttatacttg atactcacac tcattttgta tggatttaga aaagaatatg
    48781 tgtcttgaca gttattagta agtgagttat actaagtcga catttatgtg tcaagacata
    48841 ttaggagaga gaaaaaatga gaaaaaattc agttcgaaaa ctaacgattt ctgctttatt
    48901 gattgggatg ggggtcatta tcccaatggt catgcctaaa atcatgattc caccagcttc
    48961 ctttactttg gcgtctcatg tgccattatt tattgcgatg ttttttacac caggagttgc
    49021 agtggctgtt gcgctaggta cgacatttgg tttcttttta acaacgccgg ttatcatcgc
    49081 attgcgagca ttgtcacatc ttgtgtttgc gttgattggg gcttggtact tgcaaaagca
    49141 tccgagtatc gttttaaaaa atggacagtt tacttttgct aattggcgtt tccaagggtt
    49201 caattttgtg atcggtgtga ttcattcttt agcagaaatg ctagtagtca gcatctttta
    49261 ctttattggt aatatgcctg aaacatatta ttctcaagga tatttttata cagtattcat
    49321 cttgatgggg attggtgggc ttatccacag tttagttgat tataatattg cttattttat
    49381 agcaggaaca ctcagcaaat attttgatat ccccgtattt acggcagcaa aaaaagaaaa
    49441 tcggaaagag tcgattcaag ggtacgcgaa gaaaacgaca tattagacat gatctctcaa
    49501 aaaaaaaact ctcatctagt aatggataat aaatcctcta agatgagagt tttttgtcct
    49561 aaaaagagct gcaccaacat cttctggcac agctctaaca gggggcaatt tatggaagtt
    49621 tgatgacttg ttctgtttct ttatcaaaga agtggccttt gctgatgttg aaggcaaggt
    49681 cgactatttc gcctggttta tggaaatctc ttgcatctac ttttgagatg aactcagtag
    49741 aaccagtttt tgtgtaaagc atcgtttcag ctccaagtaa ttcggaaacg acaacttctg
    49801 atttcactac ggcttcaggt gaagcttcaa gggctacttg ttcactgtgg atgtcttctg
    49861 gacgaatacc gaagataact tcttttcctt cataaccttt ttcaactaat actttgtttt
    49921 ttccttcagg aatacgaagc ttaagcccat gtccatctgt gataacacca tttttcaatg
    49981 tcacattaaa gaagttcatg gcaggagatc caataaagcc ggcaacgaac atattgacgg
    50041 gtgtatcata aacttctttc ggtgtaccga tttgttggat aaatccgtct ttcatgataa
    50101 cgattcggtc agccatagtc attgcttctg tctgatcgtg agtaacatag atggtcgttg
    50161 tttcaagacg ctggtgaagt ttggcaatct cagcacgcat ggctacacgt aatttagcat
    50221 ctaaatttga taatggctca tccattaaga agacttttgc atcccgaacg attgcccgtc
    50281 ccaatgccac acgttggcgt tgtccaccag ataaagcagc tggttttcgt ttcaagtatt
    50341 ctgtcagacc taagatctct gctgcattgt ccacacgttt tttgatgtct gctttatcat
    50401 atttacgtaa tttcaagcca aaagccatat tatcaaaaac agtcatatga ggatacaatg
    50461 cgtagttttg gaaaaccatg gcaatatcac ggtctttagg tgccacgtca ttcatgactt
    50521 ttccgccgat atttagttct ccttcagaga tatcttccag tcccgcgatc attcgcaaag
    50581 tagttgactt tccacaaccg gaaggaccaa caaaaacgat aaattcacgg tctttgattg
    50641 atagattaaa atcagttaca gaataatttt ctgcattgtc atatttttta tatacgtttt
    50701 tcagagccat ttctaccata atacgttcca cactttcttt tttagtttta ttaactattt
    50761 aaagtataaa tgaaagcgtt aactaacttc aatgtcatgt tgaacaagaa ttttttcttt
    50821 tttttgtcaa tgtgctagtt ttaagcttta ataaatatcc ataagaaata aaaactgata
    50881 cactggagta aataagtatg ttaacaatat caaaaggagt gtctcttatg aaaatcgctt
    50941 tgatcgctca tgaccgaaaa aaacctatga tggtgaaatt agcaacagcg tataaaacaa
    51001 tattggaaaa acatgaactt tttgctaccg ggacgactgg gcagaggatc acggaagcaa
    51061 ccggcttgcc gatccatcgg tttaaatccg gaccgttagg cggggatcag caaattggag
    51121 ccatgatttc ggaggatcag ttagatttgg tgatttttct tcgagacccg ctggctgcac
    51181 agccccatga accagatgta acagcactta tccgtttatc tgatgtctat gagattccgt
    51241 tagctacgaa tatcggaaca gctgaggtgc tactaagagg actggaagcc ggcttcctag
    51301 attttcgaag aatcgtccat gaaatagaca agcatccact ttcattttga tggataagcg
    51361 tatggaaaaa taacgtttaa tgttcgccta tatgtagcta taaaagctaa acaaactgat
    51421 aatatgcgat ataatacgaa cgtattggat aatataaaca ataatattag tttttcgtat
    51481 ttgcagtaaa tgtgaaaata tgctatagtt tctgtgggaa aagatcccaa aaataataca
    51541 gagtagaaaa taaagcgtta agtgctaaga ggatgggatg ttgcctcttg gacgaaggac
    51601 gtaatgttcg cggttttatt ttcgcattcg ctgcatgata cgatgtagca gctcttaaag
    51661 gagatgctaa aaatgaagaa acaccggtta gacgcacgta tgattgctat tatgggctta
    51721 ttgattgcat tgatggtcac tttgtcccga ctggtagcaa tcgagacccc atttattaaa
    51781 atcagtgtca catttattcc acaagtgatc atgggcattc tttttggtcc tttttggtca
    51841 gggataggcg cagttttagc tgatttagta ggaatggccc tcttctcgaa atctgcattc
    51901 tttattggat ttacattgaa tgcatttatt gaaggagcaa tctacggatt ctttttctat
    51961 cgaaaagaga tcacttggaa aaatgccatt ctggctacgc ttagtgtcac gctgatcatc
    52021 aacttatttt tgacaccatt atggcttgcg ttgatgtacc atgtgccatt gttcagctgg
    52081 gtcgtttggg cgccccgcct gttaaaaaca gtaatatggt taccgattca atcaattgcc
    52141 atttattacg taggacgtag tattccttac aaaaaaattt taagaagttt agcgatccac
    52201 gctaaataaa aaacaagcag tcttcccatc ccagaagact gcttgttttt attgtgctgt
    52261 gaattgtgct tgatagagcc gtcggtaata accatctttt tgaagcagct catcatgggt
    52321 gcccatttcg acaatagctc cctgatccat cactaatatc tggtccgcat ttttgattgt
    52381 ggacaggcga tgggcaatca caaaactggt ttttccttcc atcattgcta agaaggcttg
    52441 ttggattttt ttctctgtca atgtatcgac tgagctggta gcttcatcta agatcaacat
    52501 agggggatta ctgatcatcg ttcgagcaat cgtcaacagt tggcgttgtc catctgatat
    52561 ctttaaccct tgaccgccaa tcttagtatc taatttttcc ggcaaacgtt ctacaaattc
    52621 atacatataa gaggctttta gggcatcatt gatttctgcg tcacttgctt ccggattccc
    52681 aaaacgaaga ttttctcgca atgtactgtc aaatagccaa gtatcttgta acaccattcc
    52741 aaaactttta cgtaatgtat cacgttggat agagcggatg tcatggtcat cgactgtaat
    52801 tgttcctttt gttgtgtcat aaaaacgcat cagcaaatta acaagtgtgg attttccggc
    52861 ccctgttttt cctactatag caatggtttg acctggataa gcagtaaaat tgaaatcttc
    52921 gatcaaacgc tgcttggggt cataagaaaa agaaacatga tcaaaagaga cttttccttt
    52981 gatatttttg ggttccaagg cataggcatc tggcaaatca ggcttttctt ctggctgatc
    53041 gatcaaatca aatgctcgtt ctagaccaga aaaagcggtt tgcagttgtg tcgtgattcc
    53101 agaaagttcg ataaatggtt tagaaaactg acttgagtag atcgtaaagc tggaaatcac
    53161 accaacagtg attgacgaac cactcttcaa tgccaatagg ccgccaacta aaccaatcga
    53221 taaataagca aggtgatcta caaaacgaga agacgggttt gtcaaggaag aagaaaattg
    53281 tgcccgttgt cctttttcat atagatcagc atttagcagt tcaaattgct gttgactagc
    53341 ttcttcttgc tgaaaagctt tcacgatttt ctggttaccg attcgttcgg tcacaaagcc
    53401 cgagatatcc ccaataatcc tttgctgtct atcgaaattt gtttgtgaag cacgagcaac
    53461 gatccaactc acaaggaaaa taattggtgt agaacaaaga acgaccaatg tcagaagtgg
    53521 acttagacgc atcataaaaa taaacgaaag aatgatgatt gccactccag aaaataattg
    53581 attgaaggcc gcagaaattg caatggaaat attgtccata tcatttgtaa atcgactgac
    53641 gatatttccg tgggagtttt gatcataata acgaagtggc aatcgattca gatgagcaaa
    53701 tgcatctttt cttaattttg caacggataa gtaagctaac cgattgctta acacttggat
    53761 gagccattga ctgactacgt tgattaaaac gataccaccg aatagaataa gtaaatggaa
    53821 cagtcgattg aagcggacct gtccttctcc aatcatttga tcgatacttt gaccaatttg
    53881 taacgtcatc acaactgttg caatcccatt gatgattcct agtatcacag ctagccaaat
    53941 gtcttttgca taggcagtaa ggtaaggaat gaatcggcgg agcgtctgca aggataattt
    54001 ttttactttc ataactattc ttcctcctgt gatgcgacga tttcctgata ttctgctgat
    54061 tgagcaagta attcttcatg ggtaccctga gcagcaatct taccttgatc catcactaag
    54121 atatgatgtg cttcttgaat agagcggaca cgttgggaga taataatcac tgtactgcca
    54181 agataagtct gtagcgcctt acgcaaatcc aagtctgttt gataatccaa cgcacttaaa
    54241 gagtcatcta aaatcagtaa tgctggcttg gcaatcaaag ctcttgcaat cgtcagtcgc
    54301 tgtttttgtc cgccagagaa atttttccca ttttccatga cttttgtatc taaaccattt
    54361 ggaagctgac ggacaaattc ttctgcctga gcgattttca gagcttccca acattctttt
    54421 tctgtggcgt ctttcttacc ccattgaagg ttttcacgaa tagtcccggt aaatagtaca
    54481 gaagtttggg gaacaagagc aatttgctga cggagatgat ccagctgcca agaacgaaca
    54541 tccattccgt ccattataac tgtaccggaa ctgacatcat agaaacgcgg aatcaattgt
    54601 gtcaaagtcg ttttcccgct tccggttgga ccaatgattc caaggactgt atttcgcttc
    54661 agctgaaatg taatattttg gagagaaaga ccagaatcag gagtataacg gaagtcaaca
    54721 tggtcaaaag cgataattgc ttcagaagaa aaatcgggag tagtactgac ctcagcttca
    54781 agaatcgaat tttctgtgtc tagcacctct ttcacccgat ttcctgaagc ttcggcacgt
    54841 gtgaagatca cgacgaggtt tgaaacaacg atcagtgcca aaagcatttg attcatataa
    54901 ttgatcaaag caagaacttg tccttgttgc aagctaccaa tatttacttt gatcccgcca
    54961 actgtcagca aacagatgat cccgacattc atgatcaagg ttgtagcagg tgataatagg
    55021 gcagagatat tggaaacacg taaataattg ttcgctagat catttgtgct tttatcgaac
    55081 ttctctgttt ctttttttgt ctgcgcaaat gcgcggatga cacgaacacc gctaagattc
    55141 tgactaacgt gttcattgag ctgatctagt ttttcttgca ctttttggta gagaggaacg
    55201 gtttttttga tgataaaaaa taaaatgatt gagaaaatag gcaataatgc taagaaaaac
    55261 agacctactt cccagtcgat cacaaaagcc atgaccactg acccgatact taaaaacggt
    55321 gctctgatca ataaacgaat gaccattgct aaagctagct gaagctgatt gatgtcgttt
    55381 gtcattcggg tgatcaaggt atctgttcca aaatgattca actcgttgtg agagaaagta
    55441 ttgatttttt tgattagctg attacgtaac tctgtaccaa atccttgtga agctactgaa
    55501 gcatagtatt ggcaaatgat agcacaaatc agaccaatca cagacatagc gaccatccat
    55561 aagcccattt caatgatttt tcctcggtca ttcattttta gtccattatc gatcaaggaa
    55621 gccatcatta aaggcaggac aagttcgaag acagcttcaa gaaatttgaa gaacgggccc
    55681 aaaatgattt gcttacgata gtcttttgca taacgtaata actgaatcat atgattcctc
    55741 ctattattta tttgtccaca attgaaaaaa caagtactac cacattgtag cttaggaaat
    55801 ttagaatgaa aagagaacaa gccttttcat aaatgaaagt tttattatga agaagcttta
    55861 gaaattgaat agactatttt ttttaaaaaa aagaaaatga gaaaacatgc cagtctcttc
    55921 attcatagga acgtctattt tacttaattt ttctataaat gaattctgca taaaaaatat
    55981 atcaagtaaa tgtttataga tgaaactcta
//
LOCUS       DAPBAF010000015        55720 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.015, whole genome shotgun sequence.
ACCESSION   DAPBAF010000015 DAPBAF010000000
VERSION     DAPBAF010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 55720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55720
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.015"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            1..369
                     /locus_tag="RD451_001037"
     CDS             1..369
                     /locus_tag="RD451_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HDT7566314.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            549..1490
                     /locus_tag="RD451_001038"
     CDS             549..1490
                     /locus_tag="RD451_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HDT7566315.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            1559..2290
                     /locus_tag="RD451_001039"
     CDS             1559..2290
                     /locus_tag="RD451_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HDT7566316.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            2434..4614
                     /locus_tag="RD451_001040"
     CDS             2434..4614
                     /locus_tag="RD451_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HDT7566317.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            4634..5116
                     /locus_tag="RD451_001041"
     CDS             4634..5116
                     /locus_tag="RD451_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HDT7566318.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            5132..5893
                     /locus_tag="RD451_001042"
     CDS             5132..5893
                     /locus_tag="RD451_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HDT7566319.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            6024..7358
                     /locus_tag="RD451_001043"
     CDS             6024..7358
                     /locus_tag="RD451_001043"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HDT7566320.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            7665..8150
                     /locus_tag="RD451_001044"
     CDS             7665..8150
                     /locus_tag="RD451_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydratase"
                     /protein_id="HDT7566321.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            8143..8826
                     /locus_tag="RD451_001045"
     CDS             8143..8826
                     /locus_tag="RD451_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HDT7566322.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGITLAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            8952..11597
                     /gene="polA"
                     /locus_tag="RD451_001046"
     CDS             8952..11597
                     /gene="polA"
                     /locus_tag="RD451_001046"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HDT7566323.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELAEKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            11642..12478
                     /gene="mutM"
                     /locus_tag="RD451_001047"
     CDS             11642..12478
                     /gene="mutM"
                     /locus_tag="RD451_001047"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HDT7566324.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            12442..13071
                     /locus_tag="RD451_001048"
     CDS             12442..13071
                     /locus_tag="RD451_001048"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HDT7566325.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEKLVGQIENWLFANRFL"
     gene            13123..13455
                     /locus_tag="RD451_001049"
     CDS             13123..13455
                     /locus_tag="RD451_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HDT7566326.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHIPDEQKIEEQRMKH
                     YTGIEEKL"
     gene            13767..14258
                     /gene="nrdR"
                     /locus_tag="RD451_001050"
     CDS             13767..14258
                     /gene="nrdR"
                     /locus_tag="RD451_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HDT7566327.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            14281..15654
                     /locus_tag="RD451_001051"
     CDS             14281..15654
                     /locus_tag="RD451_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HDT7566328.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            15654..16580
                     /gene="dnaI"
                     /locus_tag="RD451_001052"
     CDS             15654..16580
                     /gene="dnaI"
                     /locus_tag="RD451_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HDT7566329.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            16709..17149
                     /locus_tag="RD451_001053"
     CDS             16709..17149
                     /locus_tag="RD451_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566330.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSSDSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            17293..17994
                     /locus_tag="RD451_001054"
     CDS             17293..17994
                     /locus_tag="RD451_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HDT7566331.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            17991..19112
                     /locus_tag="RD451_001055"
     CDS             17991..19112
                     /locus_tag="RD451_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HDT7566332.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            19127..20359
                     /gene="pepT"
                     /locus_tag="RD451_001056"
     CDS             19127..20359
                     /gene="pepT"
                     /locus_tag="RD451_001056"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HDT7566333.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            20491..21399
                     /locus_tag="RD451_001057"
     CDS             20491..21399
                     /locus_tag="RD451_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HDT7566334.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            21434..21706
                     /locus_tag="RD451_001058"
     CDS             21434..21706
                     /locus_tag="RD451_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HDT7566335.1"
                     /translation="MDVLLHNPLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            21717..22763
                     /locus_tag="RD451_001059"
     CDS             21717..22763
                     /locus_tag="RD451_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HDT7566336.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            23014..25623
                     /gene="clpB"
                     /locus_tag="RD451_001060"
     CDS             23014..25623
                     /gene="clpB"
                     /locus_tag="RD451_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HDT7566337.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQSNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(25774..26460)
                     /locus_tag="RD451_001061"
     CDS             complement(25774..26460)
                     /locus_tag="RD451_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566338.1"
                     /translation="MEGLSVIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGIT
                     FIVESLLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWD
                     KILHAVSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLC
                     DQFLGMNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFE
                     SYKLEKVKNT"
     gene            complement(26438..26932)
                     /locus_tag="RD451_001062"
     CDS             complement(26438..26932)
                     /locus_tag="RD451_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HDT7566339.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            complement(26952..28172)
                     /locus_tag="RD451_001063"
     CDS             complement(26952..28172)
                     /locus_tag="RD451_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7566340.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            28319..30154
                     /gene="lepA"
                     /locus_tag="RD451_001064"
     CDS             28319..30154
                     /gene="lepA"
                     /locus_tag="RD451_001064"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HDT7566341.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEQDSVK"
     gene            30350..31261
                     /locus_tag="RD451_001065"
     CDS             30350..31261
                     /locus_tag="RD451_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7566342.1"
                     /translation="MVDNSSGRVLKSLRKEKKLSQKKLADLAGISQSTLVKYEKGSRK
                     IPKDVDNTLSKILNIETLIKDEEDKIEILIGKLIAYRDMNKLLNKELADNIGISEVLL
                     SYVLNRKRNPSKEMQKKIDIFLLSNEKEILKEINRDSEIFSLSKDDKIVMGKRIREVR
                     KNREETLEKFGKNFTIYTGKNVISRWEKGINIPDIEKLMNIAYLGKVTVPYLMYGEDY
                     KNILPKDERVSDFKKINSFSMGLRMRKIRKDYYLEREEFGKLFSPSISKWSIDRYENG
                     RDIPNTNRIIQYAYIGNLSLEFLIYGI"
     gene            32257..32508
                     /locus_tag="RD451_001066"
     CDS             32257..32508
                     /locus_tag="RD451_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566343.1"
                     /translation="MRKVLVFNTRGQSFLGIEGTRVTVDGWCDCFEVGKHVELMAFTE
                     LKDKNNVEFFESDIGWDDHEEVYGKFILRKGNSYTNGEA"
     gene            32591..32863
                     /locus_tag="RD451_001067"
     CDS             32591..32863
                     /locus_tag="RD451_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566344.1"
                     /translation="MSDGFEQVSIIKNQVREILRKKGYLVDSYFEGDYETWVGVYARP
                     ENKPTYLDPTTSEDAYLQNRYRVDGFKQDFAEWFEWEIENGEVKEE"
     gene            32953..33192
                     /locus_tag="RD451_001068"
     CDS             32953..33192
                     /locus_tag="RD451_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566345.1"
                     /translation="MIDISLPEDLKPDPVTIGNSVMIFDSLDEAMSYGWKEIKDEGSN
                     WYGMRFGDGEVAKKAGIPIGKWTVDFHEAGSFFVL"
     gene            33339..37622
                     /locus_tag="RD451_001069"
     CDS             33339..37622
                     /locus_tag="RD451_001069"
                     /inference="COORDINATES: protein
                     motif:HMM:NF019941.1,HMM:NF037291.1,HMM:NF037639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VaFE repeat-containing surface-anchored protein"
                     /protein_id="HDT7566346.1"
                     /translation="MYAKTKMNWLKALALVAFSQFCFLVGTAQAHAEETTAIQPTMEA
                     IAQVASEVTEVQPAEAGVPAGEATVEQAPVTEAPTVNSKTTLDQTIGETQHPGNSPGT
                     SQPVEETASITTPASETSTLEGEKAAEATPSVQPESSEKQAEEKKRIEETVEQPAATA
                     DKEGKNEENVEKTISSTAASQNQPTKPNKESTASIENQKKKEQNIPKTGTPTLLVTVP
                     TNRSVRVRRATNAAVLGGRKIDWGENIGVTSSPNNLNFTLNYMVRFEINGQVAFCIEP
                     GVSAAEGQVYTATALKNYLKNSNVRKKTSLISYLGYVTNKDKSDEQYIAAQFMIWEAL
                     GTKIPIKNIRVDYDRRKAEIQRLINNFGEKATFNNQTHTVKIGETLKVKNKNDFLKYV
                     KDIQKPKGVNVSIHGNEVWITVTKEAPDKAKIQLNKIKVQGAPLAYRRPGAQTIGVLH
                     PTEPNASVINLQILKQGNIRVFKEDAETGVKAQGAASLENAVYGLYQADGKKIKEITL
                     KKINGKVQAEIKDLDPGKYVLKEIKAPKGYVLSDEAIEIVVEPGKTVNATAKDQVIKG
                     TIDLVKVANKDLVDSTNPDNKPKLAGIEITLTSKTTGKVVKTVVTDNDGYATFGKNTV
                     VFDTYILSETKGKEGYKLFEPLEVTISENGQTFHYVLEDKVIEQRLKVVKVDQETGKV
                     IPLANTEFKIFDTLANRYVTMEIPNDTETTDIFKTNEKGFFLTNGTLTYGKDRYRLEE
                     IKAPVNYVLNQNPLVFSITNDTEPIKVIHFANRQARKSVKLFKYEEWNKKKTPLAGVN
                     FTLYNGKNQAIGEYTTDQNGEILVKGLVADDYYFLENAPLESFQPNTDKQAFTVAFKQ
                     NAPDDGETLVVSVRNYLIPPKLETQASNKADGEKVVDPLETIVIKDSVSYTNLFVGKE
                     YTISGVLMNKATNAPILQDGKEITSTLAFIADKVNGTKDLEFVVNASVLKGQTIVVFE
                     KLFRDGIEVAAHADINDEAQSVKVNNPTVHTTAVFEDGLTVADPTGLFTLNDTVEITE
                     ILPGKAYLVKGILMDKATGEPLLVHGNTVETSVGFIAKAENETVIVPFTFDLTGINGR
                     EIVVFESLFRNDEELANHKDINDKGQTVRVTNPSVRTTATHKPTGLKEVNPLTKVTIT
                     DAVKYHDLVVGKTYTVNGVLMDKVTEKPVLVDGKEVTSTLTFVAETTDGTVNLDFILD
                     ARALRGKEVVVFEDLFREGVLLASHADITDNDQTIKISNPTITTKATNKNGGKEILAL
                     PNQTVLEWVKVDGLAIGQIYRLIVQGYLTPDGTPFEGTHAEKVFAADKEMMEFLFEFL
                     VDGRNLAGKGLSFAEWLQAKTEDEKETFEEVAKHNVDLTNKDQTVQIVEAPKPPQPVK
                     PEQRVKPATVVPMLPKTGEQTSSILMVLGLVVLVIALGITLYKVRKAKD"
     gene            37721..38086
                     /locus_tag="RD451_001070"
     CDS             37721..38086
                     /locus_tag="RD451_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566347.1"
                     /translation="MAEKALRMKKEFLGQVFLLGSREPNPPKEINGVSGRYVQLQAEC
                     SREEQPAFFVYLTAEEDKRLRLPEKEVRISFEEAYFVFRKERVNSRETNDMGQTERRT
                     TGYQDVGVFLTGVKIGEVL"
     gene            38088..38540
                     /locus_tag="RD451_001071"
     CDS             38088..38540
                     /locus_tag="RD451_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566348.1"
                     /translation="MGLKFPNNYDITEALDETCLGAVRFGALEESDRVFDNETGDYTG
                     EIRSQRAQLVFGNPDEPKIARRVKFPADVDLTGFKRRDPVKLIDPEYHVVYIPAQDGN
                     REYSDLVIYAKGLEKVEAPTNNPNMKQSQEKGLDQKQPSVDSKEKEKK"
     gene            39154..40464
                     /locus_tag="RD451_001072"
     CDS             39154..40464
                     /locus_tag="RD451_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HDT7566349.1"
                     /translation="MYLIPGISIVLYLLLVSGLILGLMHWSRLKEGYFASVYWRQLLV
                     RMLIDNRFVYTKKQVSEKQTREKMRLPKVYFYQKKQELVVSFPLDGGRFHERFLKMGH
                     LLSEVFLRDLIREEREKARINYVFLSDSGRIPIDQCIAENGRIHLMKTLDWVYDQSPN
                     MLIAGAIGGGKTYLLYSLIQACLSVGTVDICDGKAADLAALGDVDVFKGHVFYKINEE
                     MIICLRNALKEMNQRYAYMKTMKDPKYEPGKNYAYYGLPPHFIFFDEWAAFYGSLDME
                     ARNRVDKLIQPLVLKGRQAGMYIILAMQRPDAEYFPSGVRDNLTFRISVGRLSPIGYL
                     MTFGEDFKNKPFYNKDQPGRGYAFPGFDVPVEFFAPFVYKDYHFIKEFEKFTEMIVYD
                     FTVKEDSQDQTMGDDNQLLQEQLERQMYLAKDPKGTSFSDAHIL"
     gene            40487..40798
                     /locus_tag="RD451_001073"
     CDS             40487..40798
                     /locus_tag="RD451_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566350.1"
                     /translation="MAESCYYRVATAIRMINPSLSSRTFYDWLNRIEQVTDYRFLRKE
                     RVFTGKVINQVLLTKKDIERLTRLYHYRVDLEEDLTLSIYRVFSPEKYSEITKLDHLI
                     L"
     gene            41159..42415
                     /locus_tag="RD451_001074"
     CDS             41159..42415
                     /locus_tag="RD451_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HDT7566351.1"
                     /translation="MTPIELKSYRKKLSAIHNISGDKKPLSQARFAQLMGCSKDYIRK
                     MEQGKRKIPEDFEQRIKERFRLYMKSGIDLRAMIDYLRLSFFGTDYKTVIQRVLRMDL
                     TEFETRPTGLYLFDCLSVRGNIWVFWHSKRTVTENVLVQFSGQGCREYEEVMREQQTD
                     WRTWLYSIWKNQGKLEAGYTRVQCSRFDIALDELWGLETEEHFDLFELLEKQKAGLLE
                     MDFKRFQNIGGCFLDDGYFRSEGLSLYFGSRKSPLFFNFYEKRFEIANREKISELEAL
                     TKYGIYNRYELRLANEKATQAVEAFILGDSPKRLGEIGVGLINAKLIVWDRLESDARI
                     VDKRWAKLFRSMEELDFTVKPEKFSLDRSERWFLKQVAPTLKLLQEADRILGRDFVQE
                     GIDNAELNDEQQNYLEWMGTSGGKIA"
     gene            42412..42957
                     /locus_tag="RD451_001075"
     CDS             42412..42957
                     /locus_tag="RD451_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566352.1"
                     /translation="MNAYTTTEWLRLLDLKAAIEALNEKMVDLSYFRFRVPYIEQAVK
                     AGRYQEKENWQEIARLLEVRKGYEQELEELEFSRRKGRLEFIRFYRFSLPIPAILAVK
                     KGCDKMKIYENCVAALSSEKPLMEEISLVTVTWEMSRQPTEEQTYLSLEEIEIELEEI
                     GRYATCSTYCGSVISIAGVIV"
     gene            42958..43458
                     /locus_tag="RD451_001076"
     CDS             42958..43458
                     /locus_tag="RD451_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566353.1"
                     /translation="MKKIMIYVGAYWSRDPTVLENPEAVHYCLRQLFYLYKERLESLI
                     RQLPYTDRRLDELLLRYPAMYKRRKNRLLPEEYPIEKHELEGRFVAYFYDDVRMRLVE
                     QRMEIENDRYYFINYCKKRKYQVTDDFYDCILQDGEVILSKIAPSFRELVPIDFLKKC
                     HLRILP"
     gene            43539..44095
                     /locus_tag="RD451_001077"
                     /pseudo
     CDS             43539..44095
                     /locus_tag="RD451_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353559.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            44115..44459
                     /locus_tag="RD451_001078"
     CDS             44115..44459
                     /locus_tag="RD451_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566354.1"
                     /translation="MWRLLFLVVCGMALFYVYRVYLYPRMERWTSWYRDPLKQRKGLK
                     RYRYELLVEFSDGRQAQYYFFANYPKYNTSELLIQLFKNNPYVGLEENGREFFYRSDN
                     ISAASMNKTRIA"
     gene            44478..45389
                     /locus_tag="RD451_001079"
     CDS             44478..45389
                     /locus_tag="RD451_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HDT7566355.1"
                     /translation="MKKTTLAVVTTLGISLFSFQLGSSLVYADETVETPKSEIVETLP
                     GEGLPDVETELNGGTTEKPAEPEQLQSEKPEKEPVTPEPEFPESTLPTDSIEEEGVHS
                     STTTDSSIVTTPEQSGTTSSSEKNTDSSSTEQPTMSSTSEEQKEEPKQPVEKSEAIPK
                     ENKPIVPAKEVTVSVTPSGEITTNTSQGMSVPIVTSNVEELTHIPTPTTPLKVAGDQT
                     IVGVKDGIPLIQDSEGNLVKDLSIPVKKLPSGNIEIKTADGKTKVLPKTGEEIHVALS
                     VLGGVLTSIAGFVGYKRKRKGIENEGN"
     gene            45468..46460
                     /locus_tag="RD451_001080"
     CDS             45468..46460
                     /locus_tag="RD451_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDT7566356.1"
                     /translation="MKKRQLRRKEKVYTEKVPKQKKIHSKKAVKWIWCLVLFLCFSGG
                     LAFFQSMKTKVQVSFLKDEIQQLQKKEVQSRSELTYTPEIESFMNRFVALYMNTFDNH
                     EQEQQRQETLKKEFYAQNFIQEPGSVSGVRKLTAASFIGLKEIETIPTASYKVTYDIR
                     SMNPESKKETSVTITQVLNLPFSISNKGCRIIAYPYFTALPKNTEKQRMITYDDTLYE
                     TVDASEAKDVEGFVEDFLDKYAKNNAKDMSYMMKEPEGLNQTAKVDQVEMKVLRYKET
                     KKPFIVKATVVFRDGDTSLLQKEQMTIVITKKTNQYYVEKLTHNWLDRKGEERK"
     gene            46457..46675
                     /locus_tag="RD451_001081"
     CDS             46457..46675
                     /locus_tag="RD451_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566357.1"
                     /translation="MTLKGIVDFILTQGGYFLIMVVVYLGLRNFMKSKVGNALISIAA
                     GAAVYFFLNDPTRVFDAFGKIIEKLFMD"
     gene            46688..47098
                     /locus_tag="RD451_001082"
     CDS             46688..47098
                     /locus_tag="RD451_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566358.1"
                     /translation="MDWEPYDYSIVYAEPYRVQQITSNWRLPFPVALVNAATFLLVVI
                     FEYLFLRSFIGWVISFFPPAGVVFYIGLPYLCVLALAKLKPDGKKVHFYLWDWFCYMI
                     RMMNGDCVYYNWDKVSNNALEELLFVNKYVYLED"
     gene            47150..49678
                     /locus_tag="RD451_001083"
     CDS             47150..49678
                     /locus_tag="RD451_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDT7566359.1"
                     /translation="MVLVKEPVKAFKKNCLLNGEDCIWAYYHVFPRTISKNTPKKTQE
                     IKEMMARLLLLLADYEDVELVMYPRTMNLRTKFDTLGKGFSPDSQAIGAYYAKETVTL
                     LEREGQVYRPSFILGIKVKEKATVESFHDVINLIWLDLAGSLARLFGLEVDDLETLFS
                     ESDPYVKEVTQLLYSFSIRPLVKKELLYLNRLQYIRGMAHKVEEQNNWEVLKDNQGTY
                     VRIPKEHKGLLQLEDELGSSYLALLPIGETPENMRNCDLFQFAQDLSFPAELRMKIHY
                     PRLKGQGGIGLKLNWLSERFKTEHKELVQNDEEPSERLLTVRGLVKHLKQRVDNGQPV
                     VDWIACFIVYGQTVEEVRQNSATVIQQLHTIIHIHRAKNDQRELFYKCLLGQPLGRQL
                     HWKHRTTVEAVGEWLFSAVSELGMESGWYIGRQDTLGDGGSRGEKTPLEELIYASNRF
                     VFLNLLAIAEGIKGALFDAPHVAVTGKTGKGKTFLVGLLFLYSSFMNVQSLFVDPKGE
                     KRKWFTKLIQDPYYQKHYPLFVEHLQKMSYVTLDATNPRNYGVLDPIVCLSRVDAKQV
                     AQDMIDELSPLGTNHLLKGAVLKGIQEVLVQKEAGQQVGLMHVVDYLEQMEQKEVREY
                     GEFLRLTVEDSILRLGFSYGENPGLDFNAKTTILEIQDLKLPNDNVRPELYTDADRKS
                     LCLMISLGRFCEMFGKRDSSKKTAIYFTEAWVFNNSNAGRSIIAAMARVGRSQMNQLV
                     LDTQFIGDLGSDKEKGNFGVVFAFDEDSEREKILNHLRLEVNEANLAEMSHMIKGQCW
                     MLDPYGRVGKLNVHSLFEEMTAALQTTEKTSHSQVEEQDTLIMQ"
     gene            49694..51904
                     /locus_tag="RD451_001084"
     CDS             49694..51904
                     /locus_tag="RD451_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566360.1"
                     /translation="MAYIKHKEKKWCVLFFLTIGFGLLFVGGLVYAAEKQVDQSIYEI
                     GKFHIDTFSSYLSDSEFSLGKMLFGANGTDFLKMMTNMFFSLSKLIWQGLDFVIEKLY
                     EGAAMNELIHQFFTFSDTIYSKIYDPIGAGIVVLYVLYLFTLRIFRGKHYAKMVFIRF
                     LFVVIFSMVWFGYGSNVPSKGEAFTKGLNDLSVEVEGFIFSATNSLDELATKDVNGVL
                     VPTTQKEAIQKVRQLYYKAAVVDPYILLNYGTTNLEELYQAEIEPQEFLAKEASSEEL
                     SDIETKVTTAAGEDRGKKKAYRVYIQPTKAVYKAVVGSMVPLLNLSIGLPLVVIGMIR
                     FIFQMLVLCLLLVIPFSLLASFVPVFDYMLMNTLKSFLGLMFQKSFYSVIILVAFLIY
                     NIVDDLIPMNTVFGFLGNMFVKALLSILLIVKRKDLLKKLGLGAADQTINNTKNIASH
                     SLSQMKQLPGQLSTAGQNLAIKGAGLAGNVYRATNPLASAAIHGFQKFQQKRTPQESV
                     KGRQVVNPFELGGRSNQALPYSGRHVRYHGVEPEMSSTKSKTEWNSGLSNGLIPNSSM
                     NSVRPKQQVQSLAQLSKQQGNNQRKPLLNKGIAFVGQSIPLPSGKVPVPQLTAAGSLS
                     QQIRQVKNQAKNGSYPAMQQLLNQYSVPNSSVATLSGNRSVQQPGQRSSESKPSISAP
                     KSLQPAFSSLDKPTEQSEKIEKDPKTLPILDAKPGTDFTLPKGRTVQKPLSKKG"
     gene            51912..53003
                     /locus_tag="RD451_001085"
     CDS             51912..53003
                     /locus_tag="RD451_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HDT7566361.1"
                     /translation="MKKGCLGCLLFFILPFFLLPFFFSGELSEHGGEATGLAVAFNGE
                     YTEGLPIFSEIKGRGPITDEHAQAAVGAAVKYQLLPSVILSQLGYESAYGQSQSGRND
                     TNFFGITWFPGCPYPQGSARGIGGSEGGFYMKFPNLKACYDYYGFMVASQSNFNQCVG
                     NKDPGSCLLILGRGGYAAAGITEGSPYYRGAMSIITSYNLTEYDTFAIKHWNSLPTKK
                     TSLIAGKSKGNAKVLDRIIGRSVNNGECYGGTAWYVSQLGGPQLMGSGHMFAMLIGED
                     YNWTTYGWQVIMNPKPSDLQAGDVVNWQAGGALSPGIYGHTGIITDVSYGGQHFSSVE
                     QNAEQGRIMARYQRTYNQTKIRSLVRKVK"
     gene            53024..53566
                     /locus_tag="RD451_001086"
     CDS             53024..53566
                     /locus_tag="RD451_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566362.1"
                     /translation="MKKGIILVFSWLCLIGLTGCHWFSSEKQKTQLRTTEETIEAVKE
                     TSGTLQSTESNSQIGSLEDETAQQMQIDEMTKNFLKDFARKWSNFTDVYKRNQAVRDY
                     MTDRCIKDNSIDVDPHVQMKTTGKLYQVTQDIENPDQYLLFGEETMNKVTQFVLLQLK
                     VDQEAQKIDAIKIYYVRSAY"
     gene            53761..54018
                     /locus_tag="RD451_001087"
     CDS             53761..54018
                     /locus_tag="RD451_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003653123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566363.1"
                     /translation="MKKLIGYSVMCIGFVGVGLFVSTESASAAEWYNPIWYNPNIECQ
                     KGYPYGPTNLKNGKCRVNWNGVVDSVITGSMDSALHGFTGH"
     gene            54032..54364
                     /locus_tag="RD451_001088"
     CDS             54032..54364
                     /locus_tag="RD451_001088"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566364.1"
                     /translation="MSEEKKEIVESLVALKDSLSKIEYVDRQEIQKLIDDTIIEIQDA
                     RCEGIKISVALSKVIEKMNRSLAFNGLKLDRQTSLIWDHLKDLYDKSKRSERTAVSIL
                     KGLWGMNS"
     gene            54409..54957
                     /locus_tag="RD451_001089"
     CDS             54409..54957
                     /locus_tag="RD451_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HDT7566365.1"
                     /translation="MKRIIKIFGVLGVFLLGLSTFVSTGTSVYATEKVNTVDLEIKNK
                     LVDELTFYFDTVGFLDEHGVYHIKDFGAIRERISQDNEQGRAARVFYEHIIVPRMEKV
                     DWKRYAGCVAINSLPGGGVAWAIGTQGDFIEALKAFNFEKAADLLLKIAEKQLGKAAA
                     KELAKVNIVAGIAAAAASCALE"
     gene            54964..55416
                     /locus_tag="RD451_001090"
     CDS             54964..55416
                     /locus_tag="RD451_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566366.1"
                     /translation="MKSLEQEHMAFKQAMFKENIYLNHNYIRVSKACSPVLNMLGGGN
                     GLYHLLFVDVCWLIFLPDELVIVNEKITSKNEVFNYSLTRINYKEITKFSLEKVPFWG
                     EFCLKIKCNWKRMYFYIDGDDALTFGKTTFSSFNFQFLLKNNFYGLLK"
     gene            55513..>55720
                     /locus_tag="RD451_001091"
     CDS             55513..>55720
                     /locus_tag="RD451_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566367.1"
                     /translation="MSIDDCLEEQIRLFLKFLKVKVQNNYFTCYSYAHPVLNSLPFNS
                     LVQGLITNIVLLVCTPNEIFVKKIG"
BASE COUNT        18940 a         9037 c        11972 g        15771 t
ORIGIN      
        1 atgtttacga atgaaataaa aatcatgctt tatgtggacg atgtagaaaa aaatgcaacg
       61 ttttggagag cagttggctt tgcggaaaaa gatcgtcaag aaatggatgg gacgcttata
      121 attgaagtag gagttgagga cagtcaaacc tcatttctgt tatatgatcg agcatttgtt
      181 gagtcccatt cacctggcac agctactagt gccccatctt tgatgtttta cagtaaagat
      241 atctttggac tatataaaaa aatgcagacg caatcagtca cattaggtga tatggtacag
      301 cttggagaag aatatgtctt taactttgct gatcccgatg gcaactactt tgcggttaca
      361 ggtaaataat agaaataaag actttgtttt tctgtgcgaa acaggaaagc gaagtctttt
      421 taattcaaat aataatatta tgtaaacaaa aaactttcca tgcgtaatta tacacaagca
      481 aataaatcgt caaatgcgaa cgccttcttt atactgttta ggaacgaaaa gaaggaagga
      541 agaaatacat ggattatcaa gtactgcttt attacaatta tacaaaaatc gaagaaccag
      601 aggaatttgc caaaaatcat ttagcctttt gcaaatcttt ggatcttaaa ggtcgtattc
      661 tagtagctga agaaggaata aatggtactg tgtctggaac cgttgaaaac acgactgcct
      721 atatgaaagc aatgaaagct gatcctcgat ttgctgatac gatgttcaag atcgatccaa
      781 gcgaaggaca tgcctttaag aagatgtttg taagataccg tccagagctt gtaagtttaa
      841 agctagaaga ggacattgat ccaaaccaag tgacaggtgc ctatctttca ccgcaagaat
      901 ttaaagaagc tattttagat gaacagacag tggtgattga tgcacggaat gattatgaat
      961 atgacttggg acattttcga ggggctgtac gcccagatat acgcagtttt cgagagcttc
     1021 cagactggat ccgcgagcac aaagaagaat ttatggaaaa acgggtagtg acctactgta
     1081 ctggtggcat tcgttgcgag aagttttctg gttggcttgt ccgtgaagga ttcaaagatg
     1141 tcggacagct gcatggcggt attgctactt atggtaagga tcctgaagtc caaggagaat
     1201 tatgggacgg caagatgtat gtgtttgatg aacggatcgc tgtcgatatc aaccaagtag
     1261 ataaacaaat cgtcggtcgc gactggtttg acggaacacc atgtgaacga tatatcaatt
     1321 gtagcaatcc tgagtgcaat cgtcagattc ttgcttccat tgaaaatgaa gaaaaacatt
     1381 taggagcatg tagcatagag tgtgcgaaac atccgcgcaa tcgctatgtt caagaccatg
     1441 gaatctctcc agaagaagca gaactgcggt ttacagcttt aattaaatag aaaacaatag
     1501 ttttgattgt cgaccatttc caatatgcgc tatactagcg ttgaggatgg tgatccacat
     1561 gaaatcattg atttatgcta ttggggatgt ccatggcaaa catgagcttt ttgaaaaact
     1621 tattcactat tatgatccaa agatccatca gcttgtttta ttaggggatc tcaatgatcg
     1681 aggtcctcgt acaaaagaat gttttttatt aggaaagcaa ttagtcgaag aaacaggagc
     1741 catttacctc cggggaaacc atgaagaata ttttttgcaa tttctgcaat caccggagga
     1801 ctggtatgcg ccttatatga gaaatggtgg aaaagaaacg tttgaaagcc tgattcaccc
     1861 aggggcatcg gaggaatact ccccaactga aatctcgatg atgatccaat cgagatattc
     1921 agaactgatt aaatttttag tccagcgccc cttgtattat gaatgggaaa attatctttt
     1981 tgtccatgcc ggtgtggatt tgacaaagaa agactggcgt aagacaagtc taagagactt
     2041 tatttggata agggaaccat ttcatgaagg gaaaaacaat acaggtaaga caattgtatt
     2101 tggacatacg attacaccaa tgctccatgg agatatgcag acaacagacc tctggattca
     2161 ggatcataaa atcggaatgg acggtggggc tgtattcgga gggtcattgc atggggttgt
     2221 ttttgacaag gaaggtattc ttcaagatat tgaatatcag aacaacgaag gaccttggca
     2281 tggaatctga ctaatggaaa gaatgaagga gctgtgactt tgttgcggct ctttttattt
     2341 ttatagagaa tattgtttct ttcagtagtt taacccagga taaaaagtat gatagaataa
     2401 agaagcaatt tttagcagaa aagaggcatt ttaatgacgg aaaatttgaa ccagacgatc
     2461 attcagcttg tacaaaaaga actttcagac tatcgtccta agcagttgac tactgtactt
     2521 aatttgttaa atgaaggaaa cactgttcct tttatcgcgc gttaccgaaa agaaatgact
     2581 ggaagtcttg atgaagtcca gattcgtgaa atcgaagagc ggtatgccta tcttgaaaac
     2641 ttagaaaaac gtaaaactga agtgattcgg ctaatcgatg aacaagggaa actgactccc
     2701 gagttagaag cagaaatcac ccaagccgtg aaaatgcaac aagtggaaga tttgtatcgt
     2761 ccatacaaac aaaaacgacg gacaaaagca acgattgcta aagaaaaagg acttgaacca
     2821 ctcgcgaagt ggctgatgca gcttacagat ggagaggtgc aatctgaagc agaaaaatat
     2881 attgacaaag aaaaagaagt ctcttctgcc gaagaagcgt tgcacggtgc tcatgagatt
     2941 attgctgaac aagtcagcga taatgcaaaa tttcggactt ggattcggtc ttatacgtat
     3001 aacaaaggta tgtatgtcag caatgtcaag gatgagcaag cagatgaaaa aggcgtatat
     3061 gaaatgtatt atgactttgc agaacccgtc cataaaatgg tttctcatcg aatattagct
     3121 actaatcgtg gagaaaaaga agatattctg aaagtattct ttcaagtaga tgaagcagca
     3181 attttagctt acttggatcg ccaaatagtc aaaaatcctg cctctccttc ttcttcattc
     3241 gtcagagaag cctatcagga tagttataaa cgctttattc agccagcaat cgagcgagaa
     3301 ctgcgcaatg aattgactga aaaggcagat gagcaagcaa tcgctatttt cggcgaaaac
     3361 ctccgtaatc ttttgttgca accgccacta aaaggtaaag ttgtcctggg atttgatccg
     3421 gcttatcgta ctggatgtaa actagcagtc gtagatgcga cagggaaagt tttagcaatc
     3481 gaagttattt atcctcataa acctgcagcg caagcaaaaa gagaagctgc tggaccagct
     3541 tttatccaat taattaataa atatcaagta gatatggtag ctatcggaaa tggtacagcc
     3601 agtcgggaat ctgaactttt tgtggctgag cagttgaaat ccgccgacca taaaacctat
     3661 tacgctatcg tcaacgaagc aggcgcttct gtttactccg ctagcgaaat tgcacgaaaa
     3721 gaatttccgc atctacaagt tgaagaaaga agtgctgttt ctattgcccg tcgcctgcaa
     3781 gatcctttag ctgaattagt caaaatcgat cctaaagctg tcggagtagg ccagtaccaa
     3841 catgacgttt ctcaaaaacg tttggctgaa caattggatt ttgttgtgga aacagcggtt
     3901 aaccaagtag gtgtggatgt gaatacagca agcccgcagc tcttgcagca tatatcagga
     3961 ttgaataaaa caactgccca aaacattgtc atttatcgtg aagaaaacgg agaattcacc
     4021 gcacgaactc aattgaaaaa agtgccacgc ttaggaccaa aagcatatga acaagcaatc
     4081 ggattcttgc gagtccctgg tgggaaaaac attttggaca acacaggtat ccatcccgaa
     4141 agttattcta ttgcaaaaga aatattaact tcagtccaac tttcagaaaa agagcttggt
     4201 acagaagaag cagtagaaaa attgacacga ttatccgtag agaaactggc tgaaagccta
     4261 tcagtcggag aagaaacgtt agccgatatt ttagctgggc tgacacaacc tggacgagat
     4321 atgcgtgatg agatgccagc gcccttatta cgtacagatg tattgagtat ggaagacttg
     4381 aaaccaggga tggaattgac tggaacggtc cgtaatgtca ttgacttcgg cgcatttgtt
     4441 gatatcggtg tgaagcaaga cggacttgtc catatatcga aactcagcaa aaaattcgtc
     4501 aagcatccta cagatgtcgt gtcagtagga gatatcgtaa cagtttggat agaacaagtc
     4561 gatacgaaaa aaggcagaat cagtttgacg atgctttccc cttatgaaga gtaacaatga
     4621 ggagtaacaa aaattgacac aagaagaact gcagcagtta gtagaagaga tatcattaaa
     4681 aagcttccag cttcctttca agcaccaagc aatgttcaat ccacgcttac gtacaactgg
     4741 cgggcgctat catttaaacg atcatcattt agattttaat gcgaagctat ttgaagagtc
     4801 agacgaagag acgattgcag gaatcatcaa acatgaactt tgccattatc atcttcatct
     4861 agctggaaga gggtatcagc ataaagatat ggatttcaag tatcttttga aaaaaacagg
     4921 agggttgcgc tatgcaccag ccttgacgaa gaaacagata aagatggagt attatcgatg
     4981 ccaagattgt tctgccacga tctgccgcaa gagaagaatc gatgtacgca aatatcgttg
     5041 tggaagatgt catggagaaa tcaaatggat tgagacaaaa agagaagact ttaatgaagc
     5101 acaaaaaatc agatgaaagg atagaaggcc tttggaaaaa agtgagcaga ggaatctaaa
     5161 agactggaat cagctattaa attttttagc cgcacctgaa gagggaaatt ttgaggaact
     5221 gacggcacct acacttattt tagctggaaa ctgtcttcct atcttagctg ataaagcagc
     5281 acaaatgtat ttaaatggcc aagtagatca attgtttttg gtcggagggg tggggcatgc
     5341 gactagaatc ctttatgaga attttgaaaa gcaaggattt cattttgaag atggcatgag
     5401 tgaaagtgaa atctgtcgtc agtatctaaa agaagtctat gatttgcccg ataaggcttt
     5461 tctgatagaa tcgaagtcta caaattctgg agagaacgcc actttttcac tggagattct
     5521 tcattcctta ggagctgtac cagaaaaaat cttattgatg aatgatccga cactgcaacg
     5581 caggactcga gcaacttttg agaaagtatg gcaaaatgaa caaactattt tcgcgaatgc
     5641 tgtgccattt gtgccggaaa tccttcactt ttctgaagag atcatcttta cagcaaaaga
     5701 actgaatcat caatggccta aggaatattt ccatgcgcta gtattaggag aaatggaacg
     5761 tctccatgac gatgagaacg gctatggtcc gaaaggaaaa gattttattc ctcacattga
     5821 tatatcagag gaagtttggt cttcttacac cagaattaaa gagtcaataa aaacggattt
     5881 ttctcgtact tgaccatttt agcaagcgaa tcctcctttc caaataaatt tggttgaaat
     5941 tttcaatcgt ttataagata atgaggagcg tgttgaatgt aatagctaaa agaatggacg
     6001 ctagataaga gaagaggatt caaatggaaa atcaaaataa attgtatcat tttgttggta
     6061 tcaaaggttc aggaatgagc tccttggctc ttgttttaca tgaacaaggt ctaaatgtcc
     6121 aaggatcaga cattgaaaaa tatttcttta cacaaagaga tttagaaaaa gcaaatatca
     6181 cgattctgcc atttaacgca gataatgtaa aaccagggat gacgatcatt gcaggaaatg
     6241 catttcctga ttcacatgaa gaaatccagc gagcaaaaga attaggtttg gaagtgattc
     6301 gctatcacga ctttattggt cattttatcc aaaattatac gagtatcgct gtaacaggct
     6361 ctcacggaaa aacaagtacg actggactgc tctctcatgt attgagtggt gtccgtccaa
     6421 caagttatct aattggagat ggaacaggac atggtgatcc gcaagcggaa ttcttttcat
     6481 ttgaggcctg tgaatatcgc cgtcatttcc ttgcctattc accagactat gcaatcatga
     6541 ccaatatcga ttttgatcat ccggattatt atacaagtat cgacgatgta tttacagctt
     6601 tccaaacaat ggctggacaa gtgaaaaaag ctatttttgc gtatggtgac gatgcttatt
     6661 tacgcaaatt aaaagcaaat gtgccgattt attattatgg tgtcacagaa aacgatgata
     6721 tccaagcacg aaacatcgaa cgcacaactt ctggttctgc ttttgatgtc tatcatgggg
     6781 atgaatttgt tgggcacttc actgtaccag cattcggtaa acacaatatc ttaaatgctt
     6841 taggtgttat tgcagtagct tatttcgaaa aactggatct gaaagaagtt gcagaagaaa
     6901 tgctgacttt cccaggagta aaacgtcgat tcagtgaaaa gatcgtagca gacatgaccg
     6961 tagtcgatga ttatgcgcat caccctgcag agatcaaagc aacgattgat ggcgcacgcc
     7021 aaaaatatcc agataaagaa ataattgcag ttttccaacc ccatacgttt acgcgtacga
     7081 ttgcattgat ggatgaattt gcagaagcac ttgatttagc tgataaagtt tacttatgcg
     7141 atatttttgg ttcggctcgg gaagaacaag gaaacgttaa gattgaagac cttggagcga
     7201 aaatcaaaaa aggtggagaa gtcatcaaag aaaataatgt atctccattg ttagattatc
     7261 atgatgcagt agtaatcttc atgggtgctg gagatgttca aaaatttgaa caagcgtatg
     7321 aaaaactttt aagcagcacg acgaaaaatg tactgtaata caattactgc agtgtcctta
     7381 taaaaataga aagaggggga gtggcaaaaa tcttgccaag cccccttttt tgcaacttat
     7441 gataaacggt gttcaaaagc ttgcatctgc ggtaataagc ccaatcaaat caaaaacatg
     7501 agaagctgtt ttttcttggc tgttcttatt atttgatgca ggacagcttt ttcacgacct
     7561 ctgtaaacta taggaatctg ttaaatcaag ggagcagaac ttgcctttta cgctactttt
     7621 ggtacaataa tgtatgatta aaaataaact ggagggtttc tatcttgaac ataggtaagc
     7681 cgagaaaact aggaaaaaca ataaatgaaa tcgaggaagg cgactcgtta tccttaacag
     7741 aatctattga agataaccag cttttgctgt atttgggatt gacgaatgat gcaaatcctt
     7801 tgtatatcca acatgacttt gcacaaaaaa cagaatatca acagccaatc gttccatcag
     7861 tgatgctgat ggggatcatc acaagtgcaa tttcaaagca tcttcctgga ccaggatcac
     7921 atgttgtcaa tttttctgtc aattttattg aaccggtttt ccattatgaa acactgactt
     7981 ttcagtttga ggtcataaaa gtagataaga tgaaggatgt ggtgacgatt tctgtagaag
     8041 cggagaatac gaacgaagat cgtgtgttgg atgctgtcgt tatggtccaa ccgccacaag
     8101 ttcctgaatt ggaaatagca atcgaaagtg aaggtgaatt gaatgaataa tccaagtaca
     8161 tcaatgtcag gtatcaatcg tttttatgca aaagtttatg gatttttagg tatgggactt
     8221 gcccttagtg cagtcacttc ttacttggct ctttgggtat ttcctttgca attagcaact
     8281 tttatcaata attttccact aggctttgtg ggtctgtgga tcgttgaact gattttagta
     8341 atggttctag gcgtaaaagc acaaaagaat ccgagcttag caatcggtgg atttattgcc
     8401 tactctcttt tgaatggcat aacattagcg gttactcttg catactacga tattggaaca
     8461 gtaacgcaag ctttcttgac agctactttg atgttcatgg ggatgtctgt tgtcggagta
     8521 acaacaaaaa gagatcttag cggggttgga agagcaggac aggcagcttt aatcggagtg
     8581 atcattgcac tagtcttgaa catcttcatt ttgagaagta gcgtagttga gctgttcatc
     8641 tccctactgt tagtcgtcat ctttgcaggg attacagctt atgataacca aagcatccgt
     8701 aatatctatg tccagacaaa cggaacagca catagtggaa ttgctgtatt catggcattg
     8761 aagctgtatt tggactttat caacttgttc ttggcgtttc tgagaatctt tggacggaac
     8821 aactaaaaaa gaaaaaaatt catcagttgg ggctataccg aattatttgg tatggtcccg
     8881 ctttttcttt tcgcattccg caggattctt tgttagaatg aataagaact ttacagtaag
     8941 gagttaagaa gatgacaaaa aataaattat tactcgttga tgggaacagt gtggcttttc
     9001 gcgcattctt tgcgcttcac aattctcttg aacgtttcaa aaatagaaac ggtcttcata
     9061 caaatgcaat ctatgcattc aatacgatgt ttgaaaatgt tatgcaaaaa gagcaaccga
     9121 ctcatgttct ggttgcgttc gatgcaggaa aaacgacttt tcggacagaa atgtatgcgg
     9181 agtacaaagg tggaagatcc aaaacacctg gcgaattcaa agaacaaatg ccatatatac
     9241 gtgatttgtt gacaggacta ggggtacagt attacgaatt gcccaattat gaagcagatg
     9301 atattatcgg tactttggca gaaaaagtag acaaagatca atttgatgtc gtcgtgcttt
     9361 caggtgatcg ggatttgact caattagcta gtaaagaagt aaaagtggat atcactgtaa
     9421 aaggtgtcag cgatatcgaa agctatacac cagaacatgt agcggaaaaa tatgatgggt
     9481 tgacgccaaa acagattatt gacatgaagg gactagccgg agatgcctct gacaatatcc
     9541 ccggtgtgac taaaatcggt gaaaaaacag ctatcaagct attgaaacaa tatggctcag
     9601 tcgaaggaat ttatgaacat atcgatgaaa tgaagcaaag caaaatgaaa gaaaatctga
     9661 taaatgacaa agagcaggct ttcttatcga aaaaattggc gaccatcaat acttcagcgc
     9721 ctgtggatgt ctctatcgac tcattgaagt atgaagggaa aaatctcgat aaactcgttc
     9781 cgttttataa agaaatggat ttcaatcagt tcctttctaa attgaatatc gtagaagaag
     9841 aagtaaaaat ggatgatatt ttgtttgaag tcgttcatga attcaaagag gaaatgttta
     9901 ctacggatat ggcgttgtac gtggaaatga tgggcgacaa ttatcataca gaggaaatcg
     9961 tcggagtagc gtgggggaca gaaaagaaaa tttatgtcac gaacgatcta tctgtattcg
    10021 aaaaccgagc gttccattct tggatcactg atccgactcg gctgaaaaaa gtatatgatg
    10081 cgaaacgaac ttatgttgct ttaaaccgct atactggaaa aacgaaagga atcgattttg
    10141 atgtcttgct aggtgcatac cttctcgata cgaatgaaaa aagcacagat atcgaaggaa
    10201 tagctgctca ttacggatac aacgatatcc aatcagatga agctgtatac ggcaaagggg
    10261 cgaaaaaagg tttaccagaa gaagaggaac tcttttttgc tcatttagcg cgaaaagtag
    10321 ctgcaatcaa tgcgttgaca ccaaaattga gccaagaact ggcagaaaaa aaccaagaag
    10381 atcttttccg gaaaatggaa ctgccattgt ctatcatttt ggcagagatg gaaataagcg
    10441 ggatcaaagt agatgcgact cgcttacaag aaatgaaggg cgagttctct gctcgcttaa
    10501 gagagatcga acaaaaaatc tacgaagaag ccggcgaaga attcaatttg aattcaccaa
    10561 agcaattagg agtgatctta tttgaaaaaa tgggattacc cgttatcaaa aaaacaaaaa
    10621 ctggatattc cacagccgta gatgtactgg aacagcttcg tgaacaagca ccaatcgtag
    10681 aggatatcct cacctatcgt caaattgcaa aaattcaatc tacctatgtc gagggactgc
    10741 tgaaagtgat ccaatcagat ggaaaagtgc atacccgtta tgtccagaca ttgacccaaa
    10801 caggacgatt aagctctgtt gatcctaatt tgcagaacat cccgattcga ttagatgaag
    10861 ggagaaagat acgtcaggca tttgttccta gagaaaaaga ctggctgatt tattcttctg
    10921 actattcaca aatcgagtta cgcgtacttg cgcatatctc aaatgatgaa catttgaaag
    10981 ctgccttcct agaaggtcaa gatatccatg ccagcacagc gatgcgtgta tttggaatcg
    11041 aaaaggcaga ggatgtcaca ccaaatatgc gtaggcaggc aaaagcagtg aattttggta
    11101 tcgtgtatgg catctctgat tacggacttt cacaaaatct aggaatcagc cgaaaagcag
    11161 cacagcaata catcgatacg tactttgaaa aatacccagg tgtcaaagaa tatatggaaa
    11221 gaatcgtacg cgaagcaaaa gaccaaggct acgtcgaaac gctgtatcac cgccgtcgat
    11281 atctgccaga catcaattca agaaattaca atatccgttc ttttgcggaa cgaacagcta
    11341 tcaatacacc aatccaagga agtgctgctg atattttgaa aatcgcgatg atcgaattgg
    11401 ataaacgatt aaaagaaaca ggtcttcaag ctacgatgct gttacaagtt catgatgaac
    11461 ttgtcttcga ggtaccggaa aaagaacttg aatcattaga taaattggtg aaggaagtta
    11521 tggaacaagc tgtttctctt catgtaccac tgatcactga cagcagttgg ggaaaaacgt
    11581 ggtacgaagc aaaataaaca ttgtttaaga cagagcaata taatgaaggt gaaaagaaaa
    11641 aatgccagaa ttaccagaag tagaaaccgt tcgtaaagga ttggaacggt tagtagtagg
    11701 aaaaacgatt caaaaagttc aggtcttgtg gcccaagatc atcgagcaac cagagacacc
    11761 catctttgag gcttctcttg ttggcgaaac catccaatcc attggacgta gagggaagtt
    11821 tttaattttt catctcgatc attgtgaact gatctcacac ttgcgaatgg aaggaaaata
    11881 tcaatttacg aaagaaaata caccaatcga taaacatacg catgtacttt tcttttttga
    11941 ggatggaagc caacttcgct acaacgatgt acgaaaattt ggtcgtatga caatcgtcga
    12001 aaaaggagca agtgcaactt accgaggaat catgaaattg ggacctgagc ctttgccaga
    12061 tagcttctta ttagcagatt tcgcaaatgg actgaaaaag tcccacaaag caatcaagcc
    12121 attgctgcta gaccaacgtc tagtgactgg tctaggtaat atttatgtag atgaagcatt
    12181 atgggaagcg aagatccatc cagaacaacc ggcgaacaca ctgcgcccca aagaggtaga
    12241 acaattacgt ctatcgatca ttgatgtttt ggatcgtgca atagaagccg gaggtaccac
    12301 gattcgcagt tatttgaatg cattaggaga atcaggcgga tttcaagtag cactgcatgt
    12361 ctatcagcaa actggcaaac catgtatacg ttgtggaacg ccgatcgtga aaacaaaagt
    12421 ggcacaaagg gggacgcact attgtccgaa ttgtcaaagg ctaaaaatcg caaagtagga
    12481 tttgttttag gtttgacggg tggaatagct accggtaaaa gtacggcagc caaagtcttt
    12541 cagtctcatg gatttccttt gatcgatggc gatgtgattg ccagagaaac tgttgagcct
    12601 ggaacgcttg ctctgaggaa aattgtatca gtgtttggcc aagaggtatt gcagcctgat
    12661 gggcaactag atcgagggaa acttgggatg attgtttttc catcaaagga aaaacggcaa
    12721 aaacttgatc agctattaga tccgtttatc cgaaaagcga taaaagatca aatcgcctct
    12781 ctaagttcca atcatccttt agtaattgta gatatcccat tgctctacga aggtcattat
    12841 gaccactata tggatgcagt agctgtcgtt tatactacgc cagaaactca gcttcagcgt
    12901 ttgatgaaac gtaatcaact gacgctagaa caagcgcagc agagaattag tagtcaactt
    12961 ccaatcgaag aaaaaaagca gcgtgcggat attttgttcg acaacaatgg aacaaaagaa
    13021 aaacttgtgg gacaaatcga aaattggctt tttgctaatc gctttctttg agtatctgtg
    13081 tcaattttgc tatcctgagt atatagaaag tgagggatag cgatgggatc attaaaaaat
    13141 caaaaggata aagtcgtagg taacgcaaaa gaaaaaatcg gcgagatgct caataaagaa
    13201 aatctaatcg atgaaggtcg tacgcaatca gaaacagcag aagaaaaaga aaagcagtac
    13261 caagcaagaa tcgatgaaat agaagaccag caggcagaag aagaagcgaa gcggcaagat
    13321 ttgactcaag aacgaaaaaa tccgacacct gatcgtagta aaacaccgct cccagaaagt
    13381 gaccacattc ccgatgagca aaaaatcgag gaacagcgaa tgaaacacta tacaggaatc
    13441 gaagagaagt tataaaatag taaaaaatcg agatgtgact tgaagcagat gagaaggtgt
    13501 tcatctgctt caagtttttt gtgctagatg actaaatcag cttttgtgta agttatttct
    13561 cagtaatcaa ggtgatcagt attggaaaat tgaaatttag taaggacagg ggacacaatt
    13621 acgcatgaaa gtagaaaaaa ttgttcttat atccgtgttt tttgggtagg acagtcgcgt
    13681 ttgtgatttg tttcgtgtta taatacaact agttgtaaag aaagacacat cctttatata
    13741 aaatgcgatg caagaggtga gacaaaatga gatgtcccag atgtcaacat aataattcac
    13801 gagtaatcga cagccgtcaa gcagatgatg gacgtgcgat ccgtcgccgt cgcgaatgtg
    13861 agaattgttc gttccgattc actacatttg aacgaattga agctgctccg ttattagtaa
    13921 tcaagaaaaa cggggaacgc gaagagttca atcgcgataa aattttaaga ggactcatcc
    13981 gttcagcaga aaaaagacct gtagctatgg aacaaatgga acaaatcgtc aaccatgtcg
    14041 aaaaccgcgt acgcagtctc ggagaaaacg aagtatcgac gaatctaatt ggtgaatatg
    14101 tgatggaaga tttagttgat ttagacgaaa tcgcttatat tcgttttgca agtgtttatc
    14161 gccagttcaa agatatgtct gttttcttaa aagagttgca agatatcgtg gataaagcaa
    14221 aagaaaataa taaagagaat aataaagaaa acaattaaga aacaaaaagg aggcatttcc
    14281 ttggaaaatg cttggaaaga gcttcaacca aaaaatattt accaaggaag aaaagcggct
    14341 ccgctgagag aagacagcaa gaacgccttg ctgtatcttt atcagccact aatcggcgga
    14401 gaagccttga gtatctattt caccctgtta tcagaaatct ctcaagaatc tggcaaaggt
    14461 cctgaaggga tgcatgcaga tctgcttagt agtctaggct gcggtatccc gcaattttat
    14521 gatgcaagaa aaaagctaga aggaatcggc ttactggatg tttattttaa agaagatagt
    14581 gatctgggac ctcgttttat ttatgagctg ttagaaccac tcattcctaa agcatttttc
    14641 aaagactctg ttctggcttt tcttcttctg gaaaaagttg gtgaacgacg attccagaag
    14701 cttacccaat tctttgaacc taaaaggcat acagcagagg gatatcaaaa aatcacaaaa
    14761 aaatttttag atgtttatcg cttcaatgaa gcagtgtacg ctgctaatca agaaaacatc
    14821 gaatcgctga ataaatcttt tgaagaatct gaatcagtag cattacttga agcagattcg
    14881 acattcgatt ggcagttttt gaatgattgg ctggcaaaaa aacatattgc aagtcttgat
    14941 gatccaatca tcaaacaagt cgacatgtat catcagcttt acggtttcga tgaattgaca
    15001 cttggcgaac tgatcagtca atcttatgac tttagtgaac aaaaagtatc tgaaaaagaa
    15061 ctgcaaaaag ccattttggc aatgcagaga cgtccggtga agcaaacaaa agaaacagtt
    15121 gcggtttctg aaaacagtaa tgaaccctcg tcaaacgaac atttgacaaa cgcagcgctt
    15181 cagctgataa aagaagcaca gagcattcca ccgatgaaat atctggaagc aatcaagtca
    15241 gaaaaaggcg gatatgtttc taaacaagaa aactggttac tgcaagatct tgtttctcaa
    15301 tcaggtcttt ccagtagcgt gatcaatgtt ttgctgaatt atgtactagt gatcaagaat
    15361 aatgctagct taaatgccag ttatgtaaat acagtggcaa atgaatgggc acaaaagaaa
    15421 atcgccacag cagaagaagc gatccagcac attcggcaaa taagtaatca agcaaaacaa
    15481 tcaaaacaaa agaagcaaac aaattatcaa actggcaagc gaaatgttcg acgggaaaag
    15541 cttcctgatt gggtcaacca gccaaaagat gaaaaacaga tcagcagcga gaaaaaagca
    15601 gagattgacc gccgttttaa agaatacctg gcaaaaaagg agggtgatat ctagtggaag
    15661 acgtaggcaa agaattgaag aggatcatca gcaaacgcaa ttatcaagaa aagtatgctg
    15721 aaatgatcgc tgaagtctta aatgatgcgg atgttcaagc ttttctaagc gcacaccaag
    15781 aagaattgac acaagcggat attgaaaaaa gttacgctaa attgtatgaa ttcgtgcaag
    15841 aaaagcgtaa atatcaaaaa aacgatccaa cgatgatcgc tcccggctat gagccgaagc
    15901 tgacgttgaa ttttcattat gtggatgtca cttatgtacc aacggaagca ttgttagcac
    15961 ggcaaagaca agaagaaatc agaagccgag taaaagcaat ggatatgcca aaagatattc
    16021 aatcggcttc ttttgaaaac tttgaacgta cagatggacg aggatatgcg agcttagaag
    16081 ccctagattt tgtagagaaa tatactgctg atccaaaagg gtatcataaa ggactgtatc
    16141 tagtaggaag ttttggtatt ggaaaaacat atttattagg agcaacagcg agagaattag
    16201 cgattgctgg attcaccacg acgctagtcc attttccgac atttgccgtt gagatgaaac
    16261 aggcaatcgg aaaagatcaa gtggcagaaa agttagatgc agtgaaacgt tcacctattt
    16321 tgatgatcga tgacattggt gcagatgcga tgagtagttg gatacgagac gaagtattcg
    16381 gtgttatcct tcaatatcgg atgcaggaac agttaccaac cttcttctca tcgaatttta
    16441 caatggatga attggaacag catttgtccg tcactcaacg tggagatgaa gagccgctaa
    16501 aagcgaaacg gataatggaa cgcatacgtt atttgacaaa agaaatcgaa atgactggtc
    16561 gcaaccgacg caatggttga acagttgaca agtccaactg acatttgacc tagtagtaaa
    16621 agcaggtcag cgaatcatta tatggacaga aatgaccgga gacaatcacc gcaacaagta
    16681 atgcagaaac ttaaacggag gattttttat gagggctatt ttttctagta tatctgtagt
    16741 tggtctattt tttcttttag caggctgcgg tagctcagat agcaacacag gttctgttga
    16801 ttcgattgat gcgggtcaaa cagtaaaaac aagcagtacg aaaacggaga gacaaagcat
    16861 atttgtcgga acgattgaaa gtatcactca agtagaagca gaagaagaaa cgcttcagtt
    16921 gaaactcgtc gatgtcatgg ccaaagaaga tccagcgaat atgggaacgt cattcagcaa
    16981 tgacggagtg atcttaaatg ctactgctga aaaaataagc gtggacataa atgaattgaa
    17041 aatcggtgac aaagtccaat ttacattagt tgagatgccg atcatgacga tgtctatccc
    17101 accgcaagtt cctggagatt cgattattga tgtttcattg aacaaataac caataacatt
    17161 ttttcaaaaa taagaaaatg ttgttttata gaacgaaaag gtatattttt taaggagata
    17221 tgggaatttt tttattccta gtctccttat tttatttgga aaatgctata attatctaga
    17281 aggagtgaag ctatgaacca tttagattta tctcagcgct tagccgcagt gggtgacttt
    17341 gtccctgaat ccgctcgttt agcagacatt ggatcagatc acgcttactt acccgttgca
    17401 ttgatattaa gaggaaaaat cgaatatgca gttgctggtg aagtcgttca aggtccttat
    17461 gaatcagcac gtaagcaagt caaaaaagat ggattagaag accgtatcac cgtacgcctt
    17521 gcaaatggtc tagatgctat ccagccacaa gatggtatta cagctgtcac gattgcgggt
    17581 atgggaggtt cactgatccg agatatccta gaagctggca agttgaatca acgcttaagc
    17641 ggacaagaac gtttgatcct tcagccaaac atcggagagc gtacattacg atcttggctg
    17701 caagaaaatc agtataaaat ccaatcagaa aaaatacttg aagaaaataa aaaaatatat
    17761 gaaatcattg tagccgaaaa agaacaaaaa ccagttactt acaatgaaat ggagctgatg
    17821 ttcgggccat ttctgcttga agagaaaagt gagatcttca aatcaaaatg gacaagagag
    17881 cttcaacaaa gaaaagctat ccgtgaacag ctcaaacaag cagctaatca agaggcacgt
    17941 caaaaacaaa tcgagcagga aatccaaatg attgaggagg ttttaaagcc atgacaatca
    18001 gcggacgcac tttcatccaa aagtttgaaa gctattgtcc tcagtggcta gctgaagaag
    18061 gagacccagt cggactgcat atcggaacat tggataagcc aatccaacga gtaatgatga
    18121 cattagacgt tcgtccagaa gtggtcgaag aagcaatcaa gaaaaaaatc gatttgctga
    18181 ttgctaaaca tcctccaatc tttcgtcctg taaaacggct ggttactgat cagccacaag
    18241 aaaaaatgta tgcagatttg ttgaaacatg atattgccgt ctatgcagca cacacgaaca
    18301 tggatattat ttgggatgga ctgaatgact ggttttgtga acttctcggt attgaagtgg
    18361 agagttattt agtaaagact catgagattc attataaaaa actggccgtt tatgtacctg
    18421 tggatcatgc acagaaaatg cgtgaagtat tagctgcagc tggtgctggt acacaaggtg
    18481 attataccgg tacaagtttt acctcgattg gacacggtcg atttactccg gaagctggtg
    18541 cacaaccagc gattgggaaa gtagggaaga cagaacaagt tcaagaggca aaagttgagg
    18601 ttattttgcc ggaaactatc gaaaaacaag tgattcaagc catgcggtca gctcatcctt
    18661 atgaggaacc tgcttatgat cttttcgcta tagatgaacc agtcgaaatg tttgggttag
    18721 gacgagtagg tgaattgccg caagaaattt ctatagaggc atttgtagaa caagtaaaag
    18781 aagcgttcca actagatgga ctgagaatag tccagccaaa aaatgcaaaa tcctctgtga
    18841 agcgcattgc gatttgcggt ggaagcggtg aaaaatttta tccgcaagca atcgcccaaa
    18901 gagcagatgt ctatatcacg ggagatatct attatcatac ggctcatgat atgcaaagcg
    18961 ctgggttgat tgcaattgat cccggtcatt atattgaatc gttatgcaag caacgattta
    19021 tcgagaaatt tgaatcttgg aaacaagaag aaaattggga tattaacttt ttcgtttctg
    19081 aaacaaatac aaacccattt caatttaatt aaaaggagag aatactatgt acgaaaatct
    19141 tttgccacgt tttttacgat atgtcaaaac agaaacacgc tccgatgcaa caagcaaaac
    19201 gactccatcg actcagacac aagttgcttt tgcgcaagaa ttgaaaaaag aattagaaga
    19261 gttaggctta gctgatgttt tctataatga agataacgga ttcgttatgg gaacattacc
    19321 aagcaatgtt gatcatgaag tgcgttccat tggatttatt tcccacatgg atacagcaga
    19381 ttttaatgca gtaggagtca atccacaaat cattgaaaac tatgatggcg agtctacgat
    19441 cgtactagat gcggaagaac gctatacatt gaatacaaaa gattttccaa atttgaaaaa
    19501 ttatgaaggc cacacattga tcacaacaga tggcagtaca ttactgggag cagatgacaa
    19561 atcagggatt gcggaaatca tgactgcaat ggagatcttg atcaataatc cttctatccc
    19621 tcacggtacc atcaaagtgg cttttggtcc tgatgaagaa atcggtgtcg gagcggataa
    19681 attcgatgtt gagcaattcg atgtagattt tgcttataca gtcgatggtg gtcctttagg
    19741 tgagttgcag tatgaaacgt ttagtgctgc tcaagcaaat attacgatcc aagggaaaaa
    19801 tgtacatcca gggacggcaa aagatacaat gatcaatgct ctacagttag caatcgattt
    19861 tcataatcag cttccagccg atgaagttcc agaaaaaacg gaaggatacg aaggtttctt
    19921 ccatttgatg gcattggatg ggaatcctga agaagcttct atgagttata tcattcgcga
    19981 tcatgatcgt gaaaaattcg aagcacgcaa agcacaaatc acacatatcc aagaagagtt
    20041 gaatcagcga tttgatcaag aacgaatcaa agtagatatg tatgatcaat attacaacat
    20101 gaaagaaatc attgaaaaag atatgagcat cgtggaatta gcgaaacaag caatgatcga
    20161 gcttggtatc tctccagtga tcgaaccagt tcgtggagga acagatggtt caaaaatctc
    20221 ttacatgggt attccgacgc caaatctatt tgccggagga gaaaatatgc acggacgatt
    20281 cgaatttgtt tctttacaag taatggaaaa agcaacagac gtgattgtaa aaattgcaga
    20341 attgaacaca aagagttaaa atcgaaaaag aacagcttat gacaaggcgt tcgtcccaat
    20401 gatggaatgt catctgtcta aggctaaagg gcaggacaat ggaattggtt gtcccgccct
    20461 cttttttgaa gagtaaatag gaggtaaaga atggaaaagc tgctagtttt ttataacaaa
    20521 agttcaggga aagatgaggg tgagaaatta gcacgctggt ttcaagatta tgtaaaagaa
    20581 aagcagccag aattatatgt agaactagct gaaactggcc catcgattga tgatgcggaa
    20641 ttagtcaaga aagcagaagc catagaagct gatactttag taattatagg tggagacggc
    20701 acgattcatc atatcgtcca agcgttccaa aaaacattat ctcaatacca tgtcggatta
    20761 cttccaggtg gaactgtcaa caaccttgca cgtgttcttg agattcccct caaaaaagaa
    20821 gaagctgctg acgtgatcct ggaaggcaat gtacggaaaa tagactatgg tcaagtcaat
    20881 gatgaagtca ttatctctac actgacaatc ggaatcttag cagatacagc agtttggatc
    20941 agtcaagaag aaaaacagcg ttacggctcg tggatcttta tcaagaagtt ttttaagtta
    21001 ttgctgaaga agaaaaaata tcatttggat ttagaaacag acgaggagca ttggaaagga
    21061 aaatcccaac tgttgacagt cacgatgtct aactccgtgg gcggttttac aaattttgac
    21121 gactcagcga ccctagatga tggaaaattt catgtaacga tcgtaccttc cttagatatt
    21181 ttccgattta ttttttattt gcctagaatc atgagaggca aattctatac gatccccggc
    21241 attacttatt tcacagccaa acgcatgaaa atccaagcgc aggaaaaatc tgtgggcact
    21301 cgaacggatg gagacacgac agatgatctt ccagttgaat tatctgttgt atcaaaagga
    21361 ttaacagttt attcaccaaa gaaagaagaa aaagcttaga aatagtagtt aacagaaagt
    21421 tggaagaaga gtaatggatg tattgttaca caatcctttg tggttttacc ttttcattgt
    21481 gaatttttac ttattttgtc tgatggggta tgataaacat caggctagaa ctagcggctg
    21541 gcgtgttcct gagaataatt tgatatttgt cagcctgtta ggcggtggtt tgggaggatt
    21601 gatctctcga aaagttttcc atcataaaac tcggaaaaag aagtttacta taggattcgc
    21661 tgcaggtgta cttgttgatt tgattctcat ttattttttc cattaaggag caggagatgt
    21721 cgtctaaagg aacgaaaact aaaatcattc tgaatctgct tttgctgatt gtgatttttg
    21781 ccattattta ttatttaatc aatcaatcat ttgcagatat ctttgccgaa ttgctgtcta
    21841 ccagtgttgt tgttttggca gcggctgtta tattagggac agtttaccaa atcgctgaag
    21901 ggcgctcaat caaagaaatt gctgaacctt tcgcgccgaa ttttacaacg aaagatgggt
    21961 tcttgacctc tagctatatt gcgttttacc gaatcgtttc gtttggtaca ggaacgctga
    22021 tctcggagat ttatttttat aacaaaaaag gaatgaagct atcccaggga gcaggggtga
    22081 cagcactcca tatgattatg tacaaactgg cagtgatcac ttatgcatta gctggcttgg
    22141 tcatccaatt ctctcttttt tattctaatg gtccatcaat gatctggttt atcatcgctg
    22201 gtatcctttt gacgatcgtg attgttgcct ttttattggc gatgtccgtc agcttgaatg
    22261 ttcaaatatt ttttgtcagc ttatcgaata agttatttaa aagtgagcgt ttgcggaaat
    22321 gggtggatac atgcaatcag cagatctact ctttaaggga aacggtccaa accattatcc
    22381 aagacaggac tgcgctattg cggatttatc tatggaatat gttaaaactt gtattttggt
    22441 atgtacttcc ttatttgatt ctgattgaaa accatcctaa aatagatttt ctactgacca
    22501 tttcgtttat cagctttgca gtagtgcttt caggggttat tcctacgcct gctggtattg
    22561 gttcctttga atttgtctat ttgttattat tcagaccagt tgttggaaca gttgacgcag
    22621 tttcttcgct tttactgtat cgtttcagtt cctttatctt gccatttctc tatggatttg
    22681 tgtatgtgat tgctgaacgg cgaagagtga tcaaagaaga aataatagaa gtaaaaaaag
    22741 agaataaaga aaatcaaggg taggtctttt ataagatcta ccctttttat caaatcaaag
    22801 aaaaacgtta tggataagat aattttacgt ttgtttggct ctttttttat atacatacaa
    22861 tcaattttgt ttttttaaga tttatataag tcgagaaaaa aagtcaaaaa actatgtgta
    22921 tattttgacc aaaattgacc aaagcgatat aatagttttt gtaaagatca aagaaataag
    22981 tgatcttacc tttaattagg agggtatacc tgtatgaata ttgagaaaat gactacgacg
    23041 cttcaagaag cgattgctga agctcaacag attgcggtca ctcgaaaaca tcaagatatc
    23101 gacattgccc atgtatggaa aatcttttta caatctaatc attttggtcg aaatttctat
    23161 acggatgccg gattggatgt cgaatctttt gaacatgaaa ttgatcgtct actggatgag
    23221 tatccagttg tttctggtgg aaacgtccaa tatggacaaa acctcagcca gaatttcttt
    23281 cgattattga atgaagcaga ccaaatacgt gaaagcttcg gcgacgagtt tctttcaacg
    23341 gaagtcgtta ttttagcgtt gatgaaatta aaaaattatc cgttaactgt ttatttgaat
    23401 aaaaacggat tatctgaaaa agaattgcgt aaaaacatcg aagagatgag aggaggagaa
    23461 agagtgacct cacaaaacca agaagaacaa tacaaagcat tagaaaaata cggcgttgat
    23521 ttagtacagc aagtcaaaag cggaaaaatg gatccaatca tcggtcgtga tgaagaaatc
    23581 cgtgatgtca tccgtattct ttcacgaaaa acaaaaaata atcctgttct gataggagaa
    23641 cccggtgtag ggaaaacggc aatcgttgaa gggcttgctc aacgtatcgt acgcaaagat
    23701 gtgcctgaaa atttaaaaga taaaacgatt ttttcattag atatgggtgc attgatcgct
    23761 ggagcaaaat tccgtggtga atttgaagaa agactaaaag cagtcttgaa agaagtcaaa
    23821 aaaagtgatg gacgtatcct cttgttcatc gatgaaatcc acaatatcgt aggggcagga
    23881 aaaacagaag gaagtatgga tgccggaaat ctgttgaaac caatgcttgc tcgcggtgaa
    23941 ttacatttga tcggtgccac aactttagat gagtaccgtc aatatatgga aaaagacaaa
    24001 gcgttggaac gtcgctttca aaaggtatta gtcaaagaac caacagtgga agatacgatc
    24061 agtattctgc gtggattaaa agaacgtttt gagatccacc atggtgttaa catccatgac
    24121 aacgcattag tagcagcagc tactttatct gaccgttata ttactgatcg gttcttaccg
    24181 gacaaagcaa tcgatttgat cgatgaagcc agtgcaacga ttcgggtaga aatgaactct
    24241 atgccaacgg aattagatca agttactaga cgtttgatgc agttggaaat cgaagaagct
    24301 gcactgaaaa aagaatcaga tgatgcaagt aaaaaacgct tgaaaaattt gcaagaagaa
    24361 ttagctgaac ttcgtgaaga agcaaatgcg atgaagatgc agtgggaaac agaaaaagaa
    24421 gaagtcaatt ctgtttcagc aaaacgtgct gaaatcgata aagcaaaaca cgaattagaa
    24481 gatgcagaaa ataactatga tttagaacgc gctgctgtat tgcgtcatgg tacgatacct
    24541 caattagaaa aagaattgaa ggaattagaa gctaaagcaa aagacagcga gattaagatg
    24601 gttcaagagt ccgttaccga aaatgagatt gctcaagtcg ttggcagatt aacgggtatc
    24661 cccgtaacga aacttgtaga aggtgaacga gaaaaactaa ttaaattgaa tgaaacactt
    24721 cataaacgag tgattggtca agatgaagca gttgatgcgg tcagtgacgc ggtaattcgt
    24781 tcacgggctg gattgcaaga cccaaatcgt cctctaggtt ctttcctttt cctaggacca
    24841 actggtgtcg gaaaaaccga attagcgaaa gcgttagctg agaacttgtt tgactcagaa
    24901 gatcatatgg tacggatcga tatgagtgaa tatatggaaa aacatgctgt gtctcgtcta
    24961 gtcggagctc ctccaggcta tgtaggttac gaagaaggtg gtcaattaac ggaagctgtc
    25021 agacgaaatc cttatacaat cgtcttgttg gatgaaatcg aaaaagcgca tcccgatgtc
    25081 ttcaatatct tgttacaagt cctagatgac ggacgcttga ctgattcaaa agggcgagta
    25141 gtagatttca aaaatacggt tctgatcatg accagcaata tcggttcaca gttactgctg
    25201 gaaggcgtga ctgctgatgg aacgattcca gaagcagtgg ctgaacaagt caacacgcta
    25261 ttacgtggaa acttcaaacc agaattcttg aaccgaatcg acgacacgat tttatttaca
    25321 ccattgagcc tagacaacgt gaaaggaatc gttgacaaaa tggtggcgca attggcacaa
    25381 cgtctggaac atcaagaaat cctgctgaca atcagtgatg aagccaaaac gtggattgct
    25441 gaaaatgctt atgaaccagc atatggtgca agaccattga aacgatttat cactaaggaa
    25501 gtagaaacac cactagctaa agaaatcgtt gcaggacatg ttatgcctaa atcaaaagta
    25561 acgattactt tacttgatgg acaacttcat ttcaaaacag aagagctaga agaaatcgtc
    25621 taatcttcca ttgagactat aaaagaaaaa aggggtctga cacaactagt gtcagacctc
    25681 cttttttcaa ataaacagtg ttccagaagt agtttcttcg aaaaataagc cgaaatttct
    25741 tgaagctgcc cgcttctgtc acaacctctt ttattaggta tttttcactt tttctaattt
    25801 ataactttca aagtaacgct catctttttt actttgagac catgcaaaca atcccattaa
    25861 ggcagcacct atcgtatttg tcagcaagtc gcccatcgta tccatcaatg ctgctcgtcc
    25921 gacaaacagt gtgccatcag aagcagcaaa acgttgaaga ttcatgccta agaactggtc
    25981 gcataagaat tcccagaact cccaaaacac gccgcaaagt ccagcaaacg caaagccgaa
    26041 taagaggaac aaccaaggac tggtttttga tatctcagca tctttcatca agtaaccaat
    26101 caatccatag ccaagagctg tcaggaccat tggactcacc gcatgtaaga ttttgtccca
    26161 aaaagagatg atactgatca aatgcatccc tgtgcctaaa aagacagaga tgaacaagaa
    26221 aaaccagtaa aacaaaacga ttgctgctgg tattttaagt ttgaaaactt tcaaaatgac
    26281 ttgtggcatg aaaatcaatg caatccctaa taaagattcc acgataaatg tgattccttg
    26341 agaagtcgaa tatttttgtg tgataaattc ataaaaatta tagcagacaa cgaatacacc
    26401 aaaagcaagt aaagctattt gcaccttttt gatttcttta atcactgaaa gtccctccat
    26461 ctaaaaatct ttttacttct gaaagcaact caatttctga agaaaccact tttccgttca
    26521 atttgatcaa acctattgta tataagttca ggtagtgaaa ttgattttca gctgtttctt
    26581 gtagtgcagc gatttttttc gggtgggttc cgccttgctg tcgagtatca gtatataagc
    26641 cgatcactgg gatgcctttc gcataagcca caccgatttc cgatgctacc ccggcatcga
    26701 tcgtcagccc atctagtaaa gcaatcatta aatcactagc caacactttt tctgtgtcag
    26761 caagagcaat cattcgactg tctgcataag cagttttgtc attgattgct tcattttctt
    26821 gaggaagata gatcgaaagc tcagaagaga gctctctgat ttctttaact aactgttggt
    26881 tatataacaa atcactttta gcaaacattg gtgcggcaaa ataaattttc atctaaacat
    26941 catccttttt atcaaaaata atcgctaaag taagcttcca tgtttggaat gatacgctct
    27001 agtgacttca gtgtttcttc atctgtttct aaccgttcga ttcttgccaa ataagaagca
    27061 cggcgataat tcatcatcaa gcaagtcaat gtttggatat ccagtcgaac ggattttcct
    27121 ataggttcat ttaagacacg gacttgtccc tgttcatccc atgttaaagc gaagacacca
    27181 ttattccaag gagcgacagg atcttcaatg atgaaatgaa aagcatcagc tgttccaaca
    27241 aacggaaacc gttgaaggaa ttcttttaca tcaacgatcc gagccataaa atatggttcg
    27301 atctgctctt tgatctgact atcttcaatc aaaaatgcta aaggctcatt tttataaata
    27361 tctccatgta cccagtagat catggaaaaa tgtgcggaaa taaagttcca taagccattt
    27421 cgagcttctt gatcaagata gaacatttct tttacgtgaa atatttcttc agctacccag
    27481 tagaacagaa cacctcttgg ttcatggttg ctatcgtagt agacagcggc tgtgcgctca
    27541 tcttcatttt cgaaacgcca atactcttcc caatgaaaat cactgcggaa taaagcacca
    27601 tggttttgtt gggcaaattt gtcataaacg gaaaatacgt ctggatgatc aactggtaat
    27661 cgctcaacca taccacttac tgggatttgt ttaggtagct gtgtatctct gattttaaag
    27721 gaaagtttat cagacatgat ttcccatcct ttacgccgat agtaggggat actgtaagga
    27781 tacaaataag agatccattg cttattcttg cgcatattat ccaatgcaac gataattaga
    27841 tcttgcatca atccatggtt agcatattct ggataagttc caactccagt cacaccaccc
    27901 attttataac gtgcaccgtg aatattgact tcacaaggat agatagcgat ttgagagatc
    27961 agtttatttt cgtggaacca tccgaacact ttcgatactt ccaaaatcgg ttttttggaa
    28021 cggataaaag ctcgtttatt ctcaaacccg ctttcctcga tgtctgcttc agtcacttgg
    28081 aacacatagg aaagcaattc attgaattga tcgatatgtt cttgagtgac cggttttaat
    28141 tcaagatttt ctctaaaatc tttttgatcc attttttcat ctccatttat tagcttgata
    28201 acagtatagc aaaattctac aaaaaaaact tctatagctg actaattaaa aactctttaa
    28261 attactgctt ttcgttggta taatggaaag tgctgattat atgaaaagag gagacgctat
    28321 ggatataaag aaaatgaaag aacgccaaga gcagattcgt aatttttcga tcatcgctca
    28381 tatcgaccat gggaaatcta cattggccga tcgtatttta gaaatgacgc acactgtgac
    28441 gtctcgcgaa atgcaagatc agctgttaga ctcgatggat ttggaacgtg aacgtggaat
    28501 cacgattaaa ttaaatgctg tagaactcaa ttacacagcg aaaaatggag aaacatatat
    28561 ctttcacttg attgacaccc cagggcacgt cgacttcacc tatgaagtct ctcgaagcct
    28621 tgctgcctgt gagggtgccg ttttagtggt cgatgcagca caaggaatcg aagcacaaac
    28681 attggccaat gtttatttag cgttagacaa tgatttggag atcctgccag tcatcaataa
    28741 aatcgaccta cccgcagcag atcccgaacg tgtccgtcaa gaaatcgaag acgtaatcgg
    28801 aatcgatgct agtgaagctg tattagccag tgccaaatca gggattggga ttgaagatat
    28861 tctcgagcag atcgtggaat atgttcctgc accaagtgga gacttagatg caccgctaaa
    28921 agctttgatc tttgactcta tttatgatag ttaccgcggt gttgttctaa atgtccggat
    28981 cacggacggt atggtcaaac ccggagacaa aatcaaactg atgagtaatg gcaaaacatt
    29041 tgatgttaca gaggtcgggg tcttctcgcc aaaagcagtt gctagagact ttttgatggt
    29101 cggtgatgtc ggttatatca cagcaagtat caaaactgtc caagatacac gagtagggga
    29161 tacagtaacg ttagcagaca atcctgccgc tgaagcttta ccaggttacc gaaaaatgaa
    29221 tccgatggtt tattgtggtc tttatccaat tgatacttct cgttacaacg atttgcggga
    29281 agctttagaa aaactgcaat tgaatgatgc tgctttacaa ttcgaaccag aaacctctca
    29341 agcattaggt tttgggttcc gctgtggatt cctcggactt cttcatatgg atgtcgtcca
    29401 agaacgcttg gaacgggaat tcaatctaga attgatcacg actgcaccat ccgttattta
    29461 ccatgttaat aaaacggatg gtacgactgc tacagtagat aacccggcag attttcctga
    29521 acctgtaacg attcaggatg tagaagaacc attcgtcaaa gcacagatca tggtcccaaa
    29581 tgattttgtc ggtgcagtaa tggaactttc tcaacgaaaa cggggagaat tcattacgat
    29641 ggattattta gatgattacc gagtaaatgt cgtctataat attccgcttt ctgaaattgt
    29701 ctttgacttt ttcgacaaat tgaaatcaag cacgaaaggc tatgcctcat tggattatga
    29761 aatgtctggt tatcaaaaaa gcaagttagt gaagatggac atcttgctga atggagaaaa
    29821 agtcgatgca ttaagcttta tcgttcaccg agactttgcc tatgaacgtg gaaaagcaat
    29881 cgttgaaaaa ctgaaaaaac taatcccacg ccaacaattt gaggtgccaa tccaagcagc
    29941 tattggacaa aaaatcgttg cccgttcaga catcaaagcc ttgcgtaaaa acgtcttggc
    30001 taaatgttat ggtggagatg tttctcgtaa acgtaaactc ttagagaaac aaaaagaagg
    30061 gaagaagcgg atgaaacaaa tcggctccgt cgaagttccg caagaagcct tcatggccgt
    30121 tctgaaaatg gatgagcaag atagtgtgaa ataacttata atcaatcgaa aaacctatta
    30181 aataaacctt tttgagtaga tgcaacactg aggattatct gtataaaaga ttttaaactg
    30241 tcatttggtt atcacggcga tactaaaatt aacaaaattg gaatattttt cttgaagatt
    30301 tttagctgtc agtatatgat gaaagcatct cataggaggt gcttttttca tggttgataa
    30361 ttcaagtgga agggttctta aatctctaag aaaagagaaa aaactatctc aaaaaaagtt
    30421 agctgattta gcaggtattt cacaaagtac tttagttaaa tatgaaaaag ggtcaagaaa
    30481 aatccctaaa gacgtagata atactctaag caagattctg aatatagaaa ctctaataaa
    30541 agatgaggaa gataagattg agattctcat cggtaaacta attgcataca gagatatgaa
    30601 taagttactt aacaaagagt tagctgataa tataggaatt agtgaagtat tactcagtta
    30661 tgtgttaaat agaaagagaa atccgtcaaa agaaatgcaa aaaaaaatcg atatttttct
    30721 attaagtaat gaaaaagaaa ttttgaagga gattaatcgt gatagtgaga tatttagttt
    30781 atcaaaagac gataaaattg ttatgggaaa aagaatacga gaagtccgaa agaaccggga
    30841 agagacgctt gaaaaatttg gtaaaaactt taccatctat acaggcaaaa atgttataag
    30901 tagatgggaa aaaggtatta atattccaga tattgaaaaa ctaatgaata ttgcctatct
    30961 tggtaaggtc actgttcctt accttatgta cggagaagat tataagaata tacttccaaa
    31021 agatgaaaga gttagcgatt ttaaaaagat aaattctttt agtatgggat taaggatgag
    31081 gaaaattagg aaagattatt atctagaaag ggaggagttt ggaaagcttt tttctccttc
    31141 aatttcaaaa tggtccatag ataggtatga gaatggtaga gatataccca atactaatcg
    31201 aattatccaa tatgcttata taggaaatct ttctttagaa tttttgattt acgggatata
    31261 aaaatagttt acgtcgatac ttattaagtt atcgacgttt tttattatag aaaaaattta
    31321 taaaaggagg tttcttgata tgataagaaa caaaaagggt ttgttgaaag ttgctttact
    31381 ggcagctttt ttctaagtaa ctttttgaca agctcaatgg caacacaagc ggaagaagta
    31441 atacaagaac taactgttat gaataacagc tagataaaat gggctatgta tgttatccaa
    31501 caatttagta atcactagaa gcctagcgaa agttcgcttg ataagttata gatgagtatt
    31561 gatttgtagt gtttccaaat caaaagggta cagagccaca tgaaatatgt tgtcctctgc
    31621 agcgtcagga tgggaatcca taccatggag attcggagat ctgtgaggga atacttacgt
    31681 ggttaatatg tcagttgtgt tggacgtagt aatggtcata gtgggtagat tgactgaatt
    31741 cttatatgag aaaatgaaac caacaagaag atagggttat ttatacagaa ttggggatct
    31801 tttctggaaa agtaatcgga taatgcgaga ttcgtacggt cttttttaaa tttctctaaa
    31861 aaaaacggca tcgaatgggt tgggtgattg ataagcaatg aatcatagac tgatatagaa
    31921 taaaaaatga ttctatttat ctttttacat ctatcgtttt ttcaagtagc cgcaaattat
    31981 atcagcattc aacaattttt gtatacaagt tctagtaaaa ggatctgaag aaaaagttgg
    32041 ttgttgtgaa gataaaaaaa gaatcaggtt ttactgagtt tttcttcaaa atttgtgtta
    32101 ttaggttagg acaaagataa gaagaagtat gaagatttaa aaaaggaatg aggaaaagat
    32161 agtaatttcc gattattgga gtttttttat ttataaagaa gaagcgaata agttgtgatt
    32221 cctagatttc gcgcgtgatt aattaatgag caaaaaatgc ggaaagtttt agtgtttaat
    32281 acacgaggac aaagtttctt aggtattgaa ggcacacgtg taacggttga tgggtggtgt
    32341 gattgtttcg aggttggaaa acatgttgaa cttatggcat ttactgagct aaaagataag
    32401 aacaacgtgg aatttttcga gagtgatatt ggttgggacg atcatgaaga agtttatgga
    32461 aaatttattt tgcggaaggg aaattcttat acgaatgggg aagcataagt agcgatttgt
    32521 tagagatcat tgataggatt gaaattgtcg ggaatattta tgagaatcta gagttatttg
    32581 aggtgataga atgagtgatg gttttgaaca agtatcaata attaaaaatc aagttcggga
    32641 gattcttaga aaaaaaggct atttggtaga tagttatttt gaaggagatt acgaaacatg
    32701 ggtaggtgtc tatgctcgtc cagagaataa acctacctat ttagatccta cgacgtcaga
    32761 agatgcctat ttacaaaata ggtatcgagt agatggtttt aagcaagact ttgcggagtg
    32821 gtttgaatgg gaaattgaaa acggagaagt aaaagaagaa taagagtact tgttgtatca
    32881 aaataagcca gtagaacaac caaaccagta gctagtaatg acaataatac tgaggaatcg
    32941 gatcattatg gtatgattga tatttctctt ccagaagatc ttaagccaga tcctgtaaca
    33001 attggcaata gtgtcatgat ttttgattca ttagatgaag ctatgtcata tggttggaaa
    33061 gaaattaagg atgaaggtag taattggtat ggcatgagat ttggtgatgg tgaagttgcc
    33121 aaaaaagctg gtattccaat tgggaaatgg acagttgatt tccacgaagc aggttctttt
    33181 tttgttctgt aattatagtg ggagggtaaa atcattgatg aaatgtgttc agataagagc
    33241 gccagataaa aatagaagag acagttcacg tcgttatcac ttttggtaac ggcgttttgt
    33301 tttattatat aaaattctca ggaaaaggag gaattcttgt gtatgcaaaa acgaaaatga
    33361 attggttgaa agcactcgca ttggtggctt tttctcaatt ctgtttcttg gtgggaactg
    33421 ctcaagcaca tgcagaagaa acgacggcta tacaacctac gatggaagcc attgcccaag
    33481 tcgcttctga agtgacagaa gtccaaccag cagaagccgg ggtcccagct ggtgaagcca
    33541 ctgttgaaca ggcccctgtg acagaagcgc caacggtcaa ttccaaaacg actctcgatc
    33601 agacgattgg ggaaacacaa cacccaggga atagtcctgg tacttcacaa ccagttgaag
    33661 aaactgcctc aattacaacc cctgcttcag aaacgtccac tctagaagga gaaaaagctg
    33721 ccgaagcaac gccttctgtg cagccagagt cttctgagaa acaagcggaa gaaaagaaac
    33781 gaatagaaga aacagtggaa caaccagcgg ctactgctga caaagaagga aaaaatgagg
    33841 aaaacgttga aaaaacaatc tcttcaaccg cagctagtca aaatcaacca acgaaaccaa
    33901 acaaagaatc tacggctagt attgaaaatc aaaagaaaaa agagcagaac attccaaaaa
    33961 caggtacacc tacactgtta gtaacagtac caaccaatcg ttcggttcgt gttcgccgtg
    34021 caaccaatgc agctgtttta ggtggtcgga aaattgattg gggcgaaaat attggtgtta
    34081 cttctagtcc gaacaatcta aacttcactt taaattatat ggttcgtttt gagattaatg
    34141 gacaagtggc gttttgtatt gagcctggtg tctcagccgc agaaggtcaa gtttatacag
    34201 ctactgcttt gaaaaactat ttgaaaaatt caaatgtacg gaaaaaaaca agcttgatct
    34261 cttatttagg atatgtcaca aataaagaca aatccgatga acaatacatt gcggcacaat
    34321 ttatgatttg ggaagctttg ggcacaaaaa tcccaatcaa aaatatccgt gttgattatg
    34381 atcgtcgaaa agcagaaatt caacgtttga ttaataactt tggtgaaaaa gcaactttta
    34441 ataatcaaac acatacggta aaaattggcg aaacgttgaa agtaaagaat aaaaatgatt
    34501 ttttgaaata tgtgaaagac attcaaaaac caaaaggtgt caatgtatct attcacggca
    34561 atgaagtatg gattacagtc acaaaagagg caccggataa agcaaaaatt caattgaata
    34621 aaattaaagt tcaaggtgcg ccattagcct atcgtcgtcc aggagctcaa acaattggtg
    34681 tgttacatcc aacagaacct aatgcgtctg ttattaattt acaaattcta aaacaaggaa
    34741 acattcgtgt gtttaaagaa gatgcggaaa ctggtgtgaa agcacaaggt gcagcttctt
    34801 tagaaaatgc ggtctatggt ttgtatcaag cagatgggaa aaagattaaa gaaattacct
    34861 tgaaaaaaat taacggcaaa gtacaggcag aaattaaaga tcttgatcct ggcaaatatg
    34921 ttttaaaaga aatcaaagcg ccaaaaggtt atgtgctttc tgatgaagca attgaaattg
    34981 ttgttgaacc tggaaaaact gtcaatgcga ccgcaaaaga tcaagtgatc aaaggaacca
    35041 ttgatttagt gaaagttgct aataaagatt tagtcgattc aacgaatcca gataacaaac
    35101 caaaattagc tggcattgaa atcactttga cgtcaaaaac aactggcaaa gtggtgaaaa
    35161 ccgttgtgac agacaatgat ggttatgcta cttttggtaa aaataccgtt gtctttgata
    35221 cgtacattct ttctgaaacc aaaggaaaag aagggtataa actatttgaa ccacttgaag
    35281 tcacaatttc tgaaaatggg caaactttcc attatgtttt agaagataaa gtaattgaac
    35341 aacgtcttaa agtggtgaaa gtggatcaag aaacaggaaa agtgattcca cttgctaata
    35401 cagaattcaa gatttttgat actttagcca atcgttatgt cacaatggag attccaaatg
    35461 atacagaaac aacggatatc tttaaaacca atgaaaaagg ctttttccta actaacggta
    35521 cacttactta tggaaaagat cgctatcgtt tggaagaaat caaagccccc gtaaattacg
    35581 ttttgaatca aaacccatta gtgttctcga ttaccaatga tacagaaccg atcaaagtga
    35641 tccattttgc gaaccgtcaa gcacggaaaa gtgtaaaatt attcaagtat gaagaatgga
    35701 acaagaagaa aacgccgctc gcaggtgtga actttacctt gtataacggt aaaaatcaag
    35761 caattggtga atataccact gatcaaaacg gggaaatttt agtgaaaggt ctagttgccg
    35821 atgactatta cttcttggaa aatgccccat tagaaagttt ccaaccaaat acagataaac
    35881 aagcattcac ggttgcattc aaacaaaatg cgccagatga tggggaaacg ttagtggttt
    35941 ctgtacgtaa ttacttgatt ccaccaaaac tagaaacaca agcgtcaaat aaagccgatg
    36001 gtgaaaaagt ggttgatcca ttagaaacga tcgtcattaa agacagtgtt tcttatacca
    36061 acttgtttgt cggaaaagaa tacaccattt caggagtatt gatgaacaag gcaacgaatg
    36121 cgccaatttt acaagatggc aaagaaatca caagtacctt ggcctttatt gcagacaaag
    36181 tcaatggcac aaaagacctt gaatttgtgg ttaatgctag tgttctgaaa ggtcaaacga
    36241 tcgttgtttt tgaaaaactt ttccgtgatg gcattgaagt tgcagcacat gcggatatca
    36301 acgatgaagc ccaaagtgtg aaagtgaata atccaaccgt tcataccacg gctgtctttg
    36361 aagacggatt gacagtcgca gacccaacag gattgtttac cttaaacgat accgttgaaa
    36421 ttaccgagat tcttccagga aaagcatact tggtcaaagg gatcttaatg gataaagcaa
    36481 ccggtgaacc cttgcttgtg catggaaata cggtagaaac gagtgttggc tttattgcca
    36541 aagcagaaaa tgaaacggtg atcgtaccat ttacctttga tttgacaggt ataaatggtc
    36601 gtgaaatcgt cgtgtttgaa agtcttttta gaaatgatga agaactagca aaccataaag
    36661 acatcaacga caaagggcaa acggtacgag taactaaccc aagtgtacgt acaacggcta
    36721 cacataaacc cactggcttg aaagaggtta atccattaac gaaagtcacc attacagacg
    36781 ctgtgaaata ccacgatttg gtcgttggaa aaacatacac agtcaacggt gttctaatgg
    36841 acaaagtaac ggaaaaacca gtgctagtag atggaaaaga agtcacaagt accttaacgt
    36901 ttgtggcaga aacaacggat ggtacagtca atctagactt tattctagac gcacgtgcgt
    36961 tgcgaggcaa agaagtcgtg gtctttgaag atctgtttag agaaggcgta ttattggctt
    37021 ctcacgcaga tattaccgac aatgaccaaa ccatcaaaat cagtaatcca accattacga
    37081 cgaaagcgac gaataaaaat ggcggaaaag agatcttggc cttgccaaat caaactgtgc
    37141 ttgaatgggt caaagtggac ggtcttgcga ttggtcaaat ctatcgctta attgttcaag
    37201 gctacttaac accagacggc acaccatttg aaggcactca tgcggaaaaa gtctttgcgg
    37261 ccgataaaga aatgatggaa ttcttatttg aattcttagt ggacggtcgc aatcttgcag
    37321 gaaaaggctt gagttttgcg gaatggctcc aagcgaaaac ggaagatgag aaagaaacgt
    37381 ttgaagaagt ggcgaaacac aatgtagatc taacaaacaa agatcaaacg gttcaaattg
    37441 tggaagcgcc aaaaccaccg caaccagtga aaccagaaca acgggttaaa ccagctactg
    37501 ttgtaccaat gttgccaaaa acaggtgaac aaacaagtag tatacttatg gttcttggat
    37561 tagtagtatt agtcattgct ttaggtataa cactttataa agtacgtaaa gccaaagatt
    37621 agtcatgagg aacaagcggt taggattttt aaccgcttgt ttgattgtaa tgtagaaata
    37681 tttagaattt attttggttt ttaagaggag gaaaaacttt atggcagaaa aagcattgcg
    37741 tatgaagaaa gagtttttag gtcaagtatt tttattgggt tcacgggaac ctaatccacc
    37801 aaaggaaatt aatggtgtgt ctgggcgata tgttcaatta caagcagagt gttcgcgaga
    37861 agaacagcct gctttttttg tttatctcac agctgaagag gataaaagat tacgattacc
    37921 agaaaaagag gtgcgtattt catttgaaga agcttatttt gtttttcgta aagaacgagt
    37981 gaatagtcgt gaaacaaatg atatgggaca aacagagcgt cgaacaactg gctatcaaga
    38041 tgttggtgtc tttttaactg gtgtaaaaat tggggaggtt ttgtaagatg ggattaaaat
    38101 ttccaaataa ttatgacatt acagaagcat tagatgaaac ttgtttagga gccgtacgct
    38161 ttggcgcatt agaagagtct gatcgtgtat ttgataatga aacaggcgat tatacgggag
    38221 aaattcgatc acagcgagca caattagttt ttggaaatcc agatgaacca aagattgcac
    38281 gacgagttaa atttccagca gatgtagatt tgactggttt taaacgacgt gatcctgtga
    38341 aattaattga tccagaatat catgtggtat atattccagc acaagatggc aatcgtgaat
    38401 attcagattt agtgatttat gcgaaaggat tagagaaagt agaagctcca acaaataatc
    38461 ctaatatgaa acaatcacaa gaaaaaggtt tagatcaaaa acaaccaagt gttgattcta
    38521 aggaaaaaga gaaaaaataa ggtttttttg aaagaatagg aaggagtctt cctattcttt
    38581 ttatctaaga tagaaggaag gggagatttt gaattcagat aaaaccaatc aaatactttg
    38641 agagattgtg cttgttatca aaatatccaa caattgattg agtattttgg agacaatcca
    38701 acgatttttg tacaaacaaa tgcatatatt tgtgcggtta ttgggcagtg tatgttttta
    38761 cgtgatcttg ttcgtttttc attaccgtac cagtggaaac aagatcatca ggaagtgatt
    38821 tggattcgta tagtacgaat atgtaatatg tgtgcacacc cttataaaaa tcgattaaat
    38881 ctttttcgat tatgtttttt tactaaatgt gatattcctg tattagttgc tttttgtcaa
    38941 aagtttttag cacaggaaaa gtaaaaacag aaaggaggaa tgtgacaatt gaaagctcat
    39001 tttttcaagt atcgtggtcg gcgaattcgc tatttcaatc gttatttatg gttttgctat
    39061 tatggtttct ttttgtttcc atttttgatt ctgttaggtt ggtttagttg gaaagtattt
    39121 tatccacgtt taagtacgtt ttcgaattgg caaatgtatc ttattcctgg aataagtatt
    39181 gtgttgtatt tgttgctggt tagtgggtta attttagggt tgatgcattg gtcgcgacta
    39241 aaagaaggat attttgcctc tgtttattgg cgtcagttac ttgttcgaat gttaattgac
    39301 aatcggtttg tttatacaaa gaaacaagtt agtgagaaac aaacaaggga aaaaatgaga
    39361 ttaccaaaag tttattttta tcaaaagaaa caagaattag tggtttcttt tcctttagat
    39421 ggtgggcgtt ttcacgaacg atttttaaaa atgggtcatt tgttatctga agtatttttg
    39481 cgtgatttaa ttcgtgaaga acgagaaaaa gcccgaatca attatgtatt cctttcagat
    39541 tctggtcgga ttcctattga tcaatgtata gcagaaaatg gacgtattca tttaatgaaa
    39601 actttggatt gggtatatga tcaatcacca aatatgttga ttgctggtgc aatcggtggt
    39661 gggaaaacct atttattgta ttctttaatt caagcttgtt taagtgttgg gacagtagat
    39721 atttgcgatg gaaaagcggc agatttagca gcattaggtg acgtcgatgt attcaaagga
    39781 catgtgtttt acaaaataaa tgaagaaatg attatttgtt tacgaaatgc attaaaagaa
    39841 atgaatcaac ggtatgccta tatgaaaacc atgaaagatc ctaaatatga accagggaaa
    39901 aattatgctt attatgggtt accaccgcat tttatctttt ttgatgaatg ggcagctttt
    39961 tatggttcgt tggatatgga agcgagaaat agagtcgata aattgattca gccattagta
    40021 ttaaagggtc gtcaagcagg gatgtacatt attttagcaa tgcaacgacc agatgcagaa
    40081 tattttccaa gtggtgttcg ggataattta acattccgta tttctgttgg tcgattgtct
    40141 cccattggtt atttaatgac ttttggagaa gattttaaaa ataagccatt ttacaacaaa
    40201 gatcaacctg gtcgtggata tgcttttcca ggatttgatg tacctgtaga gttttttgcg
    40261 ccatttgttt acaaagatta tcactttatc aaagaatttg agaaatttac tgaaatgatt
    40321 gtctatgatt ttacagtaaa agaggatagt caagatcaaa cgatgggaga tgataatcag
    40381 ttgttacaag aacaactaga gcgccaaatg tatttagcaa aagatccaaa aggaacaagt
    40441 ttttctgatg cgcatatttt gtaatcaact aaggaggtga agttaaatgg cagagagttg
    40501 ttattataga gtagctacag caatacgaat gattaatcct tctctttctt ccagaacgtt
    40561 ttatgattgg ttgaatcgta ttgaacaagt aactgattac cgctttttgc gcaaagaacg
    40621 tgtttttaca ggaaaagtta ttaatcaagt attgctaacg aaaaaagata tagaacgatt
    40681 gactcgattg tatcattatc gagtagattt agaagaggat ttaactttgt caatttatcg
    40741 cgttttttct cctgaaaaat atagtgaaat aacaaaatta gatcatttaa ttttgtagtt
    40801 attatctatc gggagggctc tagacgtagt ctggtagccg cactctgcct ggcggtgcgc
    40861 attaaggctg cgaagcatgg gcctataatg cgcactcgct agcagcgtgt gcagctcaca
    40921 aagaggtcgt gcgcttgcgc acggcctctt tgtgtaaagc cccccgatat ataatatggg
    40981 gggcagaaat aacataacac atagaaaaaa gttttataaa cccttttgta tcaagtgatt
    41041 atctaaggtc agcagttgta ctacttttcc caaaaaacga gggggactag ttgatatatc
    41101 ggtgtttcta aagggttaaa aaaaatcgat tttgttattt tataaaagga gcgagaaaat
    41161 gacaccgatt gagctaaaaa gctacagaaa gaagttaagt gcaattcata atataagtgg
    41221 agataaaaag ccgctatcac aagcaagatt tgcgcaattg atgggctgct caaaagatta
    41281 cattagaaag atggaacaag ggaaaagaaa aatcccagag gattttgaac aacgaatcaa
    41341 ggaacgcttt cgattgtata tgaaaagcgg aatagatctt cgagcaatga ttgattattt
    41401 gcgtctttcc ttttttggga cagactacaa aacagtgatt caacgtgtat tacgaatgga
    41461 tctgacagaa tttgaaacac gtccaacggg cttgtatctt tttgactgtc tttctgttcg
    41521 tgggaatatc tgggtgttct ggcattcaaa acgaactgta acagaaaatg tacttgtgca
    41581 attttcagga caaggttgcc gggaatatga ggaagtcatg cgtgaacaac aaacagattg
    41641 gcgaacatgg ctatattcca tttggaaaaa tcaaggaaag ttggaagctg gttatacacg
    41701 tgtgcaatgt agccgattcg atattgcgtt agatgaactt tggggattgg aaacggaaga
    41761 acatttcgat ctctttgaat tactagaaaa acaaaaagca ggtttattag aaatggactt
    41821 taagagattc cagaatattg gcggttgttt tttagatgat ggctattttc gaagtgaagg
    41881 attatctttg tattttggat cgcgaaagag tcctctcttt tttaattttt atgagaaacg
    41941 ttttgaaatt gcgaaccgag aaaaaatttc agaattagaa gcattaacga aatatggtat
    42001 ttataatcga tatgagttac ggttagccaa tgagaaagca acacaagcag tagaagcatt
    42061 tattttaggt gattcaccga aacgtttagg agagattggc gttggtttaa ttaatgcaaa
    42121 acttattgtt tgggatagac tggaaagtga tgcacggatt gttgataaac gatgggcaaa
    42181 attatttcgt tcgatggaag aattggattt tacagtaaag ccagaaaaat tctcattaga
    42241 tcgttcagaa cgctggtttt tgaaacaagt agctccgaca ttaaagttgt tacaagaagc
    42301 agatcgtatt ttaggaagag actttgtaca agaagggatt gataatgccg aactaaatga
    42361 cgagcaacaa aactatctag aatggatggg aacgtcagga gggaaaattg catgaatgca
    42421 tatacgacaa cagaatggct gcgcctgttg gatttaaagg ctgcaatcga agcattaaat
    42481 gaaaagatgg ttgatttgtc ttattttcgt tttcgagttc cttatattga acaagcggta
    42541 aaagctggac gttatcagga aaaagagaac tggcaagaaa ttgcacgctt attagaagtt
    42601 cgtaagggat acgaacaaga actcgaagag ttggaattta gccgaaggaa aggaaggcta
    42661 gaattcattc gcttttatcg attttcattg ccaatacctg cgattttagc ggttaaaaaa
    42721 ggctgcgata aaatgaagat atatgaaaac tgtgtggcag cacttagcag cgaaaaacct
    42781 cttatggaag aaatttcatt ggtgactgtc acttgggaaa tgagtcgcca gccaacagaa
    42841 gaacagacat atctttcttt agaagagatt gagatagaat tagaggaaat tggtcgctat
    42901 gccacttgtt ctacctattg tggatcggtc attagtattg ctggtgtgat tgtctaaatg
    42961 aaaaaaatta tgatttatgt tggtgcgtat tggtcacgtg atccaacagt attagaaaat
    43021 cccgaggcgg tacactattg cttgcgccaa ttattctatc tgtataaaga acgattagaa
    43081 tcgttgattc gtcagttacc atatactgac agacgtttag atgaacttct tctaaggtat
    43141 ccagcaatgt ataaacgacg aaaaaataga ttgttaccag aagagtatcc cattgaaaaa
    43201 catgaacttg aagggcgatt tgtggcttat ttctatgatg atgttcgtat gcgcttagta
    43261 gaacaacgaa tggaaataga aaatgatcgc tactatttta tcaattattg taagaagcgt
    43321 aagtatcaag taactgatga tttttatgat tgtattttac aagatgggga agtgattcta
    43381 tccaaaattg ctccaagttt tcgtgaactt gtgccgattg attttttgaa aaaatgtcat
    43441 ttgcggattc ttccgtaaaa aagagctata aaaggaaaga aaagtagaag ccaaatcggt
    43501 ttctgctttt ttattttttt taggaaggag aagatggtat gtcactggaa tttttaggag
    43561 agccaattga aaaggaagag ttcgtttcgc attatatgga tttgtttatt caggtgataa
    43621 aaaactttgt gcgattgatg aattttatcc acgcgaacaa gactatctag ccgctgaacg
    43681 aataaaaatc agtttattat gggaaaaatt cacagatgaa aataaccgac cgccagatta
    43741 tcgctattta tcagattgtt taacgaataa tgtgctttct aaagaatacc tatttcacaa
    43801 acgtgagaaa aatcaaatgt cggttgaaca tttttgtgat tgttatattg cattattgcg
    43861 tagtcaacag ttattaacag tagaacgata tggtgcagag tttggttatg tcatgcaagc
    43921 tgagcgtcat agagctacaa gatgctatga aaaagaagat caagtgattg atggctatga
    43981 agaattatgt attcgaaaca atcgctattt gcaacaacgt ttatatgaac aattgatgat
    44041 ggatttttca aatctctata gagggtatga atgttcgatg attcaagaaa ggtagaagaa
    44101 aagggggaat ttttatgtgg cgattattat ttttggtggt atgtggtatg gcattgttct
    44161 atgtgtatcg tgtctatctc tatccacgaa tggaacgatg gacaagttgg tatagagatc
    44221 ctttaaaaca acgaaaagga ttgaagcggt atcgttatga attacttgtt gaattttcgg
    44281 atgggcgaca agcacagtat tatttttttg caaactatcc aaaatacaac accagtgaac
    44341 tattgattca attattcaaa aataatccat atgttgggtt agaagaaaac ggacgggagt
    44401 tcttttatcg ttcagataat attagtgcgg cgtctatgaa caaaacacga attgcataaa
    44461 aaattggagg aataatcatg aaaaaaacaa cattagcagt cgtaacaaca ctaggaattt
    44521 cattattttc gtttcaatta gggagttcat tggtttatgc agatgaaact gtagaaacac
    44581 ctaagtcaga aattgtagaa acattgccag gggaaggatt accagatgtt gagacagagc
    44641 taaatggagg aacaacggaa aaaccagcag aacctgaaca attgcagtca gagaaacctg
    44701 aaaaagagcc agtgacacca gaaccagagt ttcctgaatc aactttaccg actgattcga
    44761 tcgaagaaga aggtgtgcat agttcaacaa caacggattc aagtatagtc acaactccgg
    44821 aacaatcagg aacaaccagt tcttctgaaa agaatactga ttcgtcaagt acggaacagc
    44881 caacgatgtc gtctaccagt gaagaacaaa aagaagaacc gaaacaacct gttgaaaaat
    44941 cagaagcaat tccaaaagaa aataaaccta ttgttccagc aaaagaagtc acagtatcgg
    45001 taaccccaag cggtgaaatt acgacgaata cttctcaagg aatgagtgta ccgattgtca
    45061 ctagtaatgt agaggaattg acccatattc caacaccaac caccccatta aaagtagcag
    45121 gtgatcaaac aattgttggt gtaaaagatg gtattccatt aatccaagat agtgaaggga
    45181 atttggtaaa ggatttgtcg attcctgtaa agaaacttcc aagtggcaat attgaaatca
    45241 aaacagcaga tggaaaaaca aaagtcttac caaagactgg tgaagaaata catgttgcac
    45301 tttctgttct aggaggagtg ttgacaagta ttgctggatt tgttggatat aaaagaaaga
    45361 gaaaaggaat agaaaatgag ggtaattgaa tggactattt ttcagaaaaa caagcttatc
    45421 gttgtcaatc gtacgtacta gtaaaaacat actagaagga gtagcttatg aaaaaacgac
    45481 aactacggcg gaaagaaaaa gtttatacag agaaagtacc gaagcaaaag aaaatccatt
    45541 caaaaaaagc agtgaaatgg atttggtgtt tggttttatt tctttgtttt tcagggggct
    45601 tggcattttt tcaatccatg aaaacgaagg ttcaagtgtc gtttttgaaa gatgaaatcc
    45661 aacaattaca aaagaaagaa gtacaaagtc ggtcagaatt aacgtacaca cctgaaattg
    45721 aatcctttat gaatcgtttt gttgctttgt atatgaatac attcgataat catgaacaag
    45781 aacaacaacg tcaagaaaca ttaaaaaaag agttttatgc acaaaacttt attcaagaac
    45841 caggaagtgt ttcaggtgtt cgaaaattaa ctgctgcttc gtttattgga ttaaaagaaa
    45901 ttgaaaccat tccaactgct agttataaag taacttatga tattcgctcg atgaatccag
    45961 agagtaagaa agaaacaagt gtgacaatca cacaagtact caatcttccc ttttctattt
    46021 caaacaaggg ctgtcgtatt attgcttatc cttattttac ggcactacca aagaatacag
    46081 aaaaacaacg aatgattact tatgatgaca cattatacga aacggttgat gcgtcggaag
    46141 cgaaagatgt tgaaggattt gtggaagatt tcttagataa gtatgcgaaa aacaatgcaa
    46201 aagatatgtc atacatgatg aaagaacctg aaggactcaa tcaaacagct aaagttgatc
    46261 aagtagagat gaaagtattg cgttataaag aaacgaaaaa accttttatt gtaaaagcaa
    46321 cggtcgtctt tcgagatggt gatacgtcac ttttacaaaa agaacaaatg acgattgtca
    46381 ttacgaaaaa aacaaatcag tattatgttg aaaaattaac acataattgg ttggatagga
    46441 aaggagaaga acggaaatga cactgaaggg aattgtagat tttatattaa cgcaaggtgg
    46501 ctatttttta ataatggtgg ttgtttatct gggattgcga aattttatga aatcaaaagt
    46561 aggaaatgca ttaatatcta tcgcagcagg tgccgcagtt tatttcttct taaatgatcc
    46621 aacacgtgta tttgatgcgt ttggtaaaat cattgaaaaa ttatttatgg attaggagga
    46681 tagtgaagtg gattgggaac cttatgatta ttcgattgtt tatgcggaac cttatcgcgt
    46741 acaacagatt acaagcaatt ggcgtcttcc atttccagtt gcattagtca atgcagcaac
    46801 ttttttgttg gtcgtaatct ttgaatattt atttttacgt tcatttattg gttgggtcat
    46861 ttcttttttt ccaccagcag gagttgtttt ttatatagga ctcccctatt tatgtgtgtt
    46921 agcactggca aaactaaaac ctgatggaaa aaaagtgcat ttttatttat gggattggtt
    46981 ttgttatatg attcgtatga tgaatggtga ttgtgtgtat tataactggg acaaggtatc
    47041 aaacaatgca ttggaagaat tactttttgt gaataagtat gtttatttag aggattagaa
    47101 aaagggacaa tcaactggtt gttccttttt tattgggagg tgaaattcat tggtgcttgt
    47161 aaaagaacca gtaaaagcat tcaagaaaaa ttgtttgtta aatggagagg attgtatctg
    47221 ggcctactat catgtttttc cacgaacaat ttcaaaaaac acaccaaaaa agacacagga
    47281 aataaaagaa atgatggctc gtttactgtt gcttttagca gattatgaag atgtggagtt
    47341 ggtgatgtat ccacgaacaa tgaatttacg gacgaagttt gacacattag gaaagggatt
    47401 ttctcccgat agtcaagcaa ttggtgcgta ttatgcaaaa gaaacagtga cattgttgga
    47461 acgagaaggt caagtctatc gtccttcatt tattttagga atcaaagtca aagaaaaagc
    47521 aacggtggag agttttcatg atgtaataaa tctaatctgg ttagatttag caggaagttt
    47581 agcacgctta tttggattag aagtagatga tttggaaact ttgttttctg aaagtgatcc
    47641 ttatgtaaaa gaagtgacac aattacttta tagcttttct attcgtccct tagtaaaaaa
    47701 agagctgttg tatctcaatc gtctgcaata tattcgagga atggctcaca aagtagaaga
    47761 acaaaataat tgggaagtac tgaaagacaa tcaaggaacg tatgtacgta taccgaagga
    47821 acataaaggc cttcttcaat tagaagatga gttagggagt agttatttag cattgttgcc
    47881 tattggggaa acacctgaaa atatgagaaa ttgtgatcta tttcaatttg ctcaggatct
    47941 ttctttccca gcagaattgc gaatgaaaat tcactatcca cgcttgaaag gacagggagg
    48001 tattggttta aaactgaatt ggctatcgga acggttcaaa acagagcata aggaattggt
    48061 tcaaaatgat gaagaaccta gtgaacgctt attaactgtt cgaggattag taaaacattt
    48121 aaagcaacga gtagataatg ggcaacctgt cgtcgattgg atcgcatgtt ttattgtata
    48181 cggtcaaacg gttgaagaag ttcgtcaaaa tagtgcaacg gttattcaac aacttcatac
    48241 gattatccat atccaccgtg caaaaaatga tcaacgagaa ttgttctata aatgtttatt
    48301 agggcaacca ttgggacggc agttacattg gaagcaccga acaactgtag aagcagttgg
    48361 cgaatggttg ttttcagcag tatcagaatt aggtatggaa tccggctggt atattggtcg
    48421 gcaagataca ttaggggatg gtggttctcg aggagaaaaa acaccattag aagaattaat
    48481 ttatgcgtca aatcgttttg tctttttgaa tcttctagcc attgcggaag gaatcaaagg
    48541 tgcgttgttt gatgcgcctc atgtagcagt aactggaaaa accggtaaag ggaagacctt
    48601 tttagttggc ttgctctttt tgtatagttc gtttatgaat gtacaaagtt tatttgtgga
    48661 tcccaaagga gaaaagcgca aatggtttac gaaactcatt caagacccgt attatcagaa
    48721 acattaccct ttgtttgtag aacatttgca aaaaatgagt tatgtcacgt tagatgctac
    48781 aaatccccgt aattatggtg tattagatcc aattgtttgt ttatcccgag tagatgcgaa
    48841 acaagtagcc caggatatga ttgatgagtt aagtccgtta ggtaccaatc accttttaaa
    48901 aggggcggta ttaaagggaa tccaagaagt tttagttcaa aaagaagccg gacaacaagt
    48961 tggcttgatg catgtggtcg actatttaga acaaatggaa caaaaagagg ttcgagaata
    49021 tggtgagttt ttacgcttga cggtagaaga ttcgatttta cgtttaggat tttcttatgg
    49081 agaaaacccg ggattagact ttaatgccaa aacaacgatt ttagagatcc aagatttgaa
    49141 attaccaaat gacaatgtcc gaccagaact atatacagat gcggatcgaa agtctttgtg
    49201 tttgatgatt agtttaggtc gtttttgtga aatgtttgga aaacgagata gtagtaagaa
    49261 aacagcgatt tattttacag aagcatgggt atttaataat tcgaacgcag gacgtagtat
    49321 tattgcagca atggcacgtg tggggcgttc ccagatgaat caattagtgt tagatacaca
    49381 atttattggt gacttaggtt cagataaaga aaaagggaat tttggtgtcg tctttgcttt
    49441 tgatgaagac agtgagcgag aaaagatttt gaatcattta cgtttggaag taaatgaagc
    49501 gaacttagct gaaatgagcc acatgattaa aggacagtgt tggatgttag atccctatgg
    49561 acgtgtagga aaactcaatg tacacagttt gtttgaagaa atgaccgctg cattacaaac
    49621 aacggaaaaa acaagtcact ctcaagtaga agaacaggat acgttaatca tgcaatagaa
    49681 atgaggtgaa acaatggctt atataaagca taaggaaaag aaatggtgcg ttttgttttt
    49741 tttaacgatt ggattcggac tgctttttgt tggtggattg gtgtatgcgg cagaaaagca
    49801 ggtggatcaa tcgatctatg agattgggaa atttcatatt gatacctttt cttcttattt
    49861 atctgatagt gaattttcat taggcaaaat gttatttggg gcaaatggca cagattttct
    49921 aaaaatgatg acgaatatgt tctttagttt aagtaaattg atttggcaag gccttgattt
    49981 tgtcattgag aagctctatg aaggagctgc aatgaacgag ttaattcacc agtttttcac
    50041 tttttcggat actatttatt caaaaatata cgatcctatt ggtgcgggga ttgtcgtctt
    50101 gtatgtgtta tatctattta ctcttcgtat atttagaggg aaacattacg caaaaatggt
    50161 gtttattcga tttctcttcg ttgtcatttt ttcaatggtt tggtttggct atggtagtaa
    50221 cgtacctagt aaaggagaag cttttaccaa agggttaaat gatttgtccg tggaggtaga
    50281 aggctttatt ttttctgcta caaatagtct agatgaattg gcgacaaaag atgtcaatgg
    50341 tgttttagtg ccaacgacac aaaaggaagc cattcaaaaa gtgcgccaac tttattataa
    50401 agcggctgtt gttgatccgt atatattgtt aaattatggg acaacaaatt tagaagaatt
    50461 gtatcaagca gagattgaac cacaagaatt tctagccaag gaagcgtcaa gtgaagaatt
    50521 atctgatatt gagacaaaag tgaccactgc tgcaggagaa gatagaggga aaaagaaggc
    50581 ttatcgtgtc tatattcaac caactaaagc tgtttataaa gcagtcgttg gttctatggt
    50641 gccattgctt aatctaagta ttggattacc acttgtagtg attggcatga ttcgttttat
    50701 ctttcaaatg ttggtgttgt gtttattact tgtgattcct ttttcattac tcgcttcttt
    50761 tgttccagta tttgattata tgctcatgaa taccttaaag tcctttttgg gcttgatgtt
    50821 tcaaaaatct ttttacagtg tgattatttt ggtggcattt ttgatctata acatagtaga
    50881 cgatttaatt ccaatgaata ctgtttttgg ttttttagga aatatgtttg tcaaagcact
    50941 cctatcaatt ttactcattg taaaacggaa agatttatta aagaaactag ggttaggagc
    51001 tgcagatcaa actataaaca acacgaaaaa catagcaagt cattctttgt ctcaaatgaa
    51061 acaactgcct ggtcaactat caactgctgg acaaaatttg gcaatcaaag gtgcaggatt
    51121 agcagggaat gtgtatcgag caacgaatcc actcgcttct gcagcgatac atggatttca
    51181 aaagtttcaa caaaaacgta caccacaaga atcggtaaaa gggaggcaag tggttaatcc
    51241 ctttgaacta ggtgggcgtt caaatcaagc cttgccttat agtggtcgtc atgttcgtta
    51301 tcatggggta gagcctgaaa tgtcttctac caaatcgaaa acagagtgga attctggtct
    51361 ttcaaatggt ttgattccaa attcgtccat gaattcagta agaccaaaac aacaggtaca
    51421 atcattggca caattgagta agcaacaagg gaataatcaa agaaaaccat tgttaaataa
    51481 aggtatcgct tttgttggtc aatcgattcc gttgccttct ggaaaagtac ccgtgccaca
    51541 attaacagct gctggttctc tttcacaaca gattcgccaa gtgaaaaatc aggcgaaaaa
    51601 tgggagttat ccagcaatgc agcagttatt gaaccaatac tctgttccta attcgtcggt
    51661 agccactcta tcaggaaatc gttctgtgca acaaccgggg caacgttcgt ctgaaagtaa
    51721 accgtcgatt tccgcaccaa aatcgttaca acctgcattt tcttctttag ataagccaac
    51781 agagcaatcg gaaaaaatag aaaaggatcc taaaacactg ccgattttgg acgcaaaacc
    51841 aggaactgat tttactttac caaaaggacg aacagtccaa aaaccattat cgaagaaagg
    51901 atgaggaaga aatgaagaaa gggtgtctag gttgtcttct tttctttatt cttccctttt
    51961 ttctattgcc attctttttt tcaggagaac tttctgagca tggaggagaa gctacaggtc
    52021 tagctgtcgc ttttaatggg gaatataccg aaggattacc gattttttca gagattaaag
    52081 gacgtggtcc aatcacagat gaacatgcgc aagcagcagt tggtgcagct gtaaagtatc
    52141 agttattacc gagtgtgatt ctttctcaat taggctatga atcagcttat ggacagtcac
    52201 aatctggaag aaacgatacg aacttttttg ggattacctg gtttcctggt tgtccctacc
    52261 cacaaggttc tgcacgtgga attggtggtt ctgaaggtgg tttctatatg aagtttccga
    52321 acttaaaagc ttgttatgac tattatggct ttatggtggc gagccaaagc aactttaatc
    52381 aatgtgtggg caataaagat cctggaagtt gtttattgat tctaggtcgt ggaggctatg
    52441 cggcagcagg tattaccgaa gggagtccgt attatcgagg agcaatgagt atcataacgt
    52501 cctataactt aacggaatat gatacttttg cgatcaagca ttggaatagc ctaccaacaa
    52561 aaaaaacttc gcttattgca ggaaaaagta aaggcaatgc gaaggttttg gatcggatca
    52621 ttggacgatc cgtaaataat ggggaatgtt atggtggtac ggcatggtat gtatctcaat
    52681 taggtggccc acagttaatg ggttctggac acatgtttgc gatgttaata ggggaagatt
    52741 ataactggac aacctatggt tggcaagtaa tcatgaaccc aaaaccaagt gatttacaag
    52801 caggagatgt ggtgaattgg caagcaggtg gtgcattgtc tcctggaatc tatggtcaca
    52861 ccggaattat aacagatgtt tcatatggcg gacaacattt ctctagtgtg gaacagaatg
    52921 ccgagcaagg acggattatg gctcggtatc aacgcacgta caatcaaaca aaaattcgta
    52981 gtctggttcg taaggtgaaa taagaaaggc agtgactaga aacgtgaaaa aagggataat
    53041 tttagtattt agttggttat gtttgatagg tcttactggt tgtcattggt tttcttctga
    53101 aaaacaaaaa acacaattga gaacgacaga agaaacaatc gaagcagtaa aagaaacaag
    53161 tggaactctt caaagtactg aaagtaacag tcaaattggt tcattagaag acgagacagc
    53221 gcaacaaatg caaatagatg aaatgacaaa aaatttctta aaagattttg ctagaaaatg
    53281 gagtaatttc acagatgttt ataaacgcaa tcaagctgtg agggactata tgacagatcg
    53341 ttgtattaaa gacaatagta ttgatgtaga cccgcatgta caaatgaaaa caactgggaa
    53401 actttaccag gtgacacaag atatagagaa tccggatcaa tatttgttat ttggagaaga
    53461 aacaatgaat aaggttactc aatttgtatt acttcaattg aaagtagatc aagaagctca
    53521 aaagattgat gcgatcaaga tttattatgt acggagtgcg tattaaaata aaaaatgaac
    53581 actcatattt attatacacc gaagaaatag aaaaaaacag actgtttttt taagaaaaac
    53641 tatgtcattc tttacttgaa aaaagttgtt ataggacaga aaggataaaa caaaaacgga
    53701 aaaaatatgt cttatgaata actataagaa ctattctatt ttttaggaga tggatacgag
    53761 atgaaaaaac taattggcta tagtgtgatg tgtattggat ttgttggtgt gggattgttt
    53821 gtatcgactg aatctgcttc tgcggctgaa tggtataatc ctatctggta taatccgaac
    53881 attgaatgtc aaaaaggcta tccgtatgga ccgacaaatc tgaaaaatgg aaaatgtaga
    53941 gtaaattgga atggcgttgt agatagtgta attactggtt caatggactc tgctctacat
    54001 ggctttacgg gtcactagaa ggaggaagaa aatgtctgaa gagaaaaaag aaatcgttga
    54061 atcattagta gctttaaaag attctctttc taagattgaa tatgttgata ggcaagaaat
    54121 tcaaaaacta attgatgata ctattattga aatccaagat gcgcgttgtg aaggtataaa
    54181 aatttctgta gctttatcta aagtaataga aaaaatgaac cgttcattag cgtttaatgg
    54241 attgaagcta gatagacaaa ctagtctgat atgggatcat ttaaaagact tgtatgacaa
    54301 gtctaaaaga agtgaacgga ctgctgtatc aatcttaaaa ggcctttggg gaatgaattc
    54361 ataaacaaga tatttaaaaa gtaacttatt ttttatggag gagaaattat gaaaagaata
    54421 attaaaatat ttggtgtttt aggtgttttc ttattaggtt taagtacttt tgttagtact
    54481 ggaacaagtg tgtatgccac agaaaaagtg aatacagttg atttagaaat aaagaataaa
    54541 ttagtagatg aattaacttt ttattttgat acagttggtt ttttagacga acatggtgta
    54601 taccatataa aggattttgg tgctattcgt gaacgaatca gtcaagataa cgaacaagga
    54661 agagcagcaa gagtctttta tgaacatatt attgttccta gaatggagaa agttgattgg
    54721 aaacgatatg ctggatgtgt agccattaat tctcttcctg gaggaggagt ggcttgggct
    54781 ataggtacgc agggagattt tattgaagca ttaaaagctt ttaattttga aaaagctgcg
    54841 gatttattat taaaaattgc agaaaaacaa ttaggaaaag ctgcagctaa agagttagct
    54901 aaggtaaata ttgtagcagg aattgcagca gctgctgcta gctgtgcatt agagtaaaag
    54961 tttatgaaaa gtttagaaca agagcatatg gcttttaaac aagcaatgtt taaagaaaat
    55021 atctatttaa accataacta tattcgtgtt tctaaggcat gttcaccagt attgaatatg
    55081 cttggaggtg gaaatggatt atatcattta ctgtttgtcg atgtttgttg gttaattttt
    55141 ttaccagatg aactagttat agtcaatgaa aaaataacaa gtaaaaatga agtgtttaat
    55201 tattctttaa caagaattaa ttacaaagag attaccaagt tttcactaga aaaagttcct
    55261 ttttggggag aattttgttt aaaaattaaa tgtaactgga aaagaatgta tttctatatt
    55321 gatggtgatg atgctcttac attcggtaaa actacttttt ctagttttaa ttttcagttt
    55381 ctattaaaaa ataattttta tggtttattg aaataaggtt gcgaaggaag atgtagagtt
    55441 atttgcactg ttgtgttggt atatctctta atgctgtgtc tttttgggga gattaattag
    55501 tggagtgatt atatgagtat agatgattgt ttagaagaac aaataagatt atttttaaag
    55561 tttttaaaag ttaaagttca aaataactac ttcacatgtt atagttatgc acaccctgtt
    55621 ttaaatagtc ttccttttaa ttctttagtg caaggattga ttacaaatat tgttttatta
    55681 gtctgtacac caaatgaaat atttgtaaaa aagataggca
//
LOCUS       DAPBAF010000016        53720 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.016, whole genome shotgun sequence.
ACCESSION   DAPBAF010000016 DAPBAF010000000
VERSION     DAPBAF010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 53720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53720
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.016"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            160..840
                     /locus_tag="RD451_001092"
     CDS             160..840
                     /locus_tag="RD451_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HDT7566368.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGPLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            930..1964
                     /locus_tag="RD451_001093"
     CDS             930..1964
                     /locus_tag="RD451_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HDT7566369.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTVPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNAFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            1978..2313
                     /locus_tag="RD451_001094"
     CDS             1978..2313
                     /locus_tag="RD451_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566370.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPIPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEQKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            2297..4777
                     /locus_tag="RD451_001095"
     CDS             2297..4777
                     /locus_tag="RD451_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566371.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLTDIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISPSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSLQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYESKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWELTAGPTS"
     gene            4833..6392
                     /locus_tag="RD451_001096"
     CDS             4833..6392
                     /locus_tag="RD451_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7566372.1"
                     /translation="MRRKLLLLKSEMLEGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     VSVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQIRYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFAITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            6389..7753
                     /locus_tag="RD451_001097"
     CDS             6389..7753
                     /locus_tag="RD451_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDT7566373.1"
                     /translation="MKIVIIGASHEGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQTIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEYTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            7924..8994
                     /locus_tag="RD451_001098"
     CDS             7924..8994
                     /locus_tag="RD451_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7566374.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAIGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            9009..9677
                     /locus_tag="RD451_001099"
     CDS             9009..9677
                     /locus_tag="RD451_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7566375.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEANELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            9697..10275
                     /locus_tag="RD451_001100"
     CDS             9697..10275
                     /locus_tag="RD451_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDT7566376.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            10676..11587
                     /locus_tag="RD451_001101"
     CDS             10676..11587
                     /locus_tag="RD451_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDT7566377.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(11965..12882)
                     /locus_tag="RD451_001102"
     CDS             complement(11965..12882)
                     /locus_tag="RD451_001102"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HDT7566378.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELDKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            13084..13521
                     /gene="zapA"
                     /locus_tag="RD451_001103"
     CDS             13084..13521
                     /gene="zapA"
                     /locus_tag="RD451_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HDT7566379.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            13579..14127
                     /locus_tag="RD451_001104"
     CDS             13579..14127
                     /locus_tag="RD451_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HDT7566380.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELWVTNILN"
     gene            14242..16602
                     /locus_tag="RD451_001105"
     CDS             14242..16602
                     /locus_tag="RD451_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HDT7566381.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEKQTIT
                     NWLQETEDGLKVQRLRGGIPIPKIENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLSDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNTYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            16689..17003
                     /gene="trxA"
                     /locus_tag="RD451_001106"
     CDS             16689..17003
                     /gene="trxA"
                     /locus_tag="RD451_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HDT7566382.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            17185..18963
                     /gene="uvrC"
                     /locus_tag="RD451_001107"
     CDS             17185..18963
                     /gene="uvrC"
                     /locus_tag="RD451_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HDT7566383.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKNFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELASKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMVKNDKHKTNELLFGTDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            19108..20007
                     /locus_tag="RD451_001108"
     CDS             19108..20007
                     /locus_tag="RD451_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7566384.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            20000..21262
                     /locus_tag="RD451_001109"
     CDS             20000..21262
                     /locus_tag="RD451_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7566385.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPIRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            21423..23321
                     /locus_tag="RD451_001110"
     CDS             21423..23321
                     /locus_tag="RD451_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HDT7566386.1"
                     /translation="MDRYLDLLSEKFPSTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETDISQFTIFTAYPEYALTTDWYKEQDKS
                     QLIHHLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFAP
                     KNSKNLSEREQEELEKIHQALSILQFKSEHQLLDRRPEFKMDDRKLLEKIDYEASTID
                     LEGQLYELKGTCFQTIQPDDPKKILEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTAKEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDTKEEGSAIINGHTPVKVKKGESPIKANGKVFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRDTTKGMELQQQITQLKR
                     LLDYRKDD"
     gene            complement(23651..24369)
                     /locus_tag="RD451_001111"
                     /pseudo
     CDS             complement(23651..24369)
                     /locus_tag="RD451_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
     gene            24706..25038
                     /locus_tag="RD451_001112"
     CDS             24706..25038
                     /locus_tag="RD451_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566387.1"
                     /translation="MKQVLEALEQIRKAEEENEKRAQTLRQQLKIYATEKEQELETIQ
                     TNYRQQLKQLVEEKEQFEIQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            25025..27028
                     /locus_tag="RD451_001113"
     CDS             25025..27028
                     /locus_tag="RD451_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HDT7566388.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFINKLKEVLDLKEKWEQLTEERDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAVIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKIKERFIHATYLIVLQGWVDAEEKQNLLHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLVEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLLVLPRGMKRFVKFFEILSIPSIIWGLIYSSFFGQSLPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALVGAMLIKNTAFVYLGAGLSIIAALCILIVPIIQTPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            27047..27517
                     /locus_tag="RD451_001114"
     CDS             27047..27517
                     /locus_tag="RD451_001114"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HDT7566389.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            27538..28122
                     /locus_tag="RD451_001115"
     CDS             27538..28122
                     /locus_tag="RD451_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HDT7566390.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQVETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAVTEMENWDESEQ
                     IQFIKNALYSLPLTGKVAFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            28137..29123
                     /locus_tag="RD451_001116"
     CDS             28137..29123
                     /locus_tag="RD451_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HDT7566391.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNIDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFESETIRKRVRQVYDA"
     gene            29113..29424
                     /locus_tag="RD451_001117"
     CDS             29113..29424
                     /locus_tag="RD451_001117"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HDT7566392.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            29446..31227
                     /locus_tag="RD451_001118"
     CDS             29446..31227
                     /locus_tag="RD451_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HDT7566393.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            31220..32596
                     /locus_tag="RD451_001119"
     CDS             31220..32596
                     /locus_tag="RD451_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HDT7566394.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            32603..33238
                     /locus_tag="RD451_001120"
     CDS             32603..33238
                     /locus_tag="RD451_001120"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HDT7566395.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            33268..34623
                     /locus_tag="RD451_001121"
     CDS             33268..34623
                     /locus_tag="RD451_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HDT7566396.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(34815..36209)
                     /locus_tag="RD451_001122"
     CDS             complement(34815..36209)
                     /locus_tag="RD451_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDT7566397.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRAQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            36301..37272
                     /locus_tag="RD451_001123"
     CDS             36301..37272
                     /locus_tag="RD451_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HDT7566398.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            37269..38051
                     /locus_tag="RD451_001124"
     CDS             37269..38051
                     /locus_tag="RD451_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HDT7566399.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(38220..38591)
                     /locus_tag="RD451_001125"
     CDS             complement(38220..38591)
                     /locus_tag="RD451_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDT7566400.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            38725..39168
                     /locus_tag="RD451_001126"
     CDS             38725..39168
                     /locus_tag="RD451_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HDT7566401.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(39211..40020)
                     /gene="yidA"
                     /locus_tag="RD451_001127"
     CDS             complement(39211..40020)
                     /gene="yidA"
                     /locus_tag="RD451_001127"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HDT7566402.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(40039..41406)
                     /locus_tag="RD451_001128"
     CDS             complement(40039..41406)
                     /locus_tag="RD451_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HDT7566403.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(41390..42220)
                     /locus_tag="RD451_001129"
     CDS             complement(41390..42220)
                     /locus_tag="RD451_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HDT7566404.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLEDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            42383..42820
                     /locus_tag="RD451_001130"
     CDS             42383..42820
                     /locus_tag="RD451_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HDT7566405.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTAGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            42896..43516
                     /locus_tag="RD451_001131"
     CDS             42896..43516
                     /locus_tag="RD451_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HDT7566406.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            43705..44211
                     /locus_tag="RD451_001132"
     CDS             43705..44211
                     /locus_tag="RD451_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HDT7566407.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            44228..45127
                     /locus_tag="RD451_001133"
     CDS             44228..45127
                     /locus_tag="RD451_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HDT7566408.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            45214..46098
                     /locus_tag="RD451_001134"
                     /pseudo
     CDS             45214..46098
                     /locus_tag="RD451_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
     gene            complement(46290..46361)
                     /locus_tag="RD451_001135"
     tRNA            complement(46290..46361)
                     /locus_tag="RD451_001135"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(46326..46328),aa:Arg,seq:ccg)
     gene            46421..47755
                     /gene="rpoN"
                     /locus_tag="RD451_001136"
     CDS             46421..47755
                     /gene="rpoN"
                     /locus_tag="RD451_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HDT7566409.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            47904..48995
                     /locus_tag="RD451_001137"
     CDS             47904..48995
                     /locus_tag="RD451_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="central glycolytic genes regulator"
                     /protein_id="HDT7566410.1"
                     /translation="MGRFKSTLDVKCPTKEIAMLDEIKMIESVAPDIIEVLQERYKIL
                     RNIYWMQPIGRRSLSESMGITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSL
                     ENFMDQLLGTHQTEQQLAEYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEG
                     ENIIAVMGGTTMAVVAEQLSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKAN
                     GNHRALYVPEQLSLATYNSLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEK
                     ELVMLKQANAVAESFGYFFNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAI
                     RAYMKNAPKQTWLITDEAAANEILKGVTL"
     gene            49036..50037
                     /gene="gap"
                     /locus_tag="RD451_001138"
     CDS             49036..50037
                     /gene="gap"
                     /locus_tag="RD451_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HDT7566411.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            50147..51337
                     /locus_tag="RD451_001139"
     CDS             50147..51337
                     /locus_tag="RD451_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HDT7566412.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            51441..52196
                     /locus_tag="RD451_001140"
     CDS             51441..52196
                     /locus_tag="RD451_001140"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HDT7566413.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            52312..53610
                     /gene="eno"
                     /locus_tag="RD451_001141"
     CDS             52312..53610
                     /gene="eno"
                     /locus_tag="RD451_001141"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HDT7566414.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
BASE COUNT        17827 a         9356 c        11351 g        15186 t
ORIGIN      
        1 ttaataaaaa aggaagaata ttcatgtaaa cgattttatt gtttttttct cttttataca
       61 aaaagggtca taatttcaag taagcggatg aattcatgag gattttttgc atactgtctc
      121 tactatactt aggtcactaa gaaaaaggag tgatttatta tgaaaaagaa catgattggg
      181 acattattac tttcaacact tcttctaggc ggcttggcaa caccagcttt tgctgagggt
      241 caagcgactt caaaaggaga tattaccttt actgaaccaa caaataccgt ggagcctctt
      301 aaccctactg atccttcaaa accagtagag ccagcagatc cggaaaatcc agcaactggc
      361 cagacaggtc ctttaacact ggatgtagtt cccgaattgc catttggtac acacgagatt
      421 gaaagcggaa caaaaacgta tcaagtagac gcttcaaaaa acgatacacc ttatctccaa
      481 gtatcagatc gtcgaggtgt aggtgcagat ggccaagcac aagggtggaa cgtgacagtt
      541 tcggtttcag attttgtaaa cggttcacaa gttttgcaag gcgctgaatt agattttgga
      601 acatccactg ttaaaagtac gtcagataac gaatccactg gaccaactag tcaaactgta
      661 actgggttga gtaaagcaag tgcagcgaca ccaatattta cagcagcaaa agatcaaggt
      721 ctgggaacat ggctttctgt ttatgatcca gcaaatatca cactgaaagt gccgaaagca
      781 gcagctggaa cattcacggc tgatttgact tggaacctcg tggctggccc agtagcatag
      841 agtatgaaat aaattcaaca aactgcggtg aaaatactat aggtgaagga ttttttaccg
      901 cagttgttgt tgaaaggatg tggtggacaa tgaatcaaag taaacgactg tttgtttcgt
      961 ttttttctat tttaagtcta tttttcattt ttccgtcaat cagccaagca aaggattcag
     1021 caggagactt tggaatcaaa ccggtatttc cagagaacca aatagataaa gcaatcggtt
     1081 attttgattt attagtggca ccggaacaaa atcagacact agaagtaatt atcagcaatt
     1141 cttcagatga agaacgaaca tttgaggtct ctgtcaatcc ggcggtaacg agtgatggtg
     1201 gaacgatcga ttatagtcaa aaaaacccaa cgttagatga gacattgccg tttgatgtcc
     1261 gtgacgtttt gctcattgcg aaaaaggaaa tcaatgtatc agcacatgca gaaacaactg
     1321 tacctataga agtgaaaatc ccagcaaaaa gctttaaggg acgtgtatta gcgggtattc
     1381 atgtttcacc taaagaagaa gctgaaacag aaaatgctac agaaggagca caaatcaaaa
     1441 atcgtattgc ttataatctc gcagtcgttt tacaagaaag tcaagagacg atagaaccgg
     1501 atctgaaact tttatcagga gatttggacg aggtcaacgc aaagccaact gttcagcttc
     1561 gtttccaaaa tcctcagcct aggattatca gcaatttgat atttacgagc aagatctttt
     1621 atgaaaatca gctttatatt gaaaatacgt ctaatgcatt tttagttgca ccaaattcga
     1681 attttcactt gaatcttgat ttagctggtg ataaagcaaa agccggcgat taccgcgcag
     1741 aaatcatagc aaaatcaggc gacagtaatg aatggcgatt tacacaaaac tttacgatca
     1801 aaaaagaaaa agcacaaaaa gtaaatgaaa attccgtttt tgcagtacaa gaacaatctt
     1861 tcccatggct ttatgcagga ttggttgctg cagttctagt gttatggttg attttgctgt
     1921 ttttgtgggt ccacaagaaa aagaaaaaag gagaaacaac atgatgaggt gatttcgttg
     1981 aaaacatcga tcttattggg agggattatt gcaagtttgc tgttcttcag ctggcaagag
     2041 ccagtccaag cagataccaa aagttcaggt acgattacat tttatgatct aagtccaatt
     2101 ccgcatccaa gtggttcagt caatggcgca tcaaaacagc agacacagct accgatttat
     2161 aaagaatcta atcaacatgg cgtattcccg gagacgaatg aacaaaagat ccgttttctt
     2221 tatttgatca ttggtataga attatggctt cttgcgtggt tgttgttatg gagaagaaag
     2281 gaaaaggagg atgaacatgt tgctacaaaa taaattttca ttttttcgct ccttcttttt
     2341 tacttcgctt tttgttttaa gtatatttat cttttcacct tcggcagaag ctgttggagc
     2401 aacgcctcct gccatttctt atgatccata cacgtatgaa aatatcgtac ctccaaatgg
     2461 tggacgtagt gcagtcaatg gcgggaagct tgtccaacta actggggcta accaattgcc
     2521 taaattgact gctacttatt tgaacgatgg ttcaaatgat ccttggaaag gtggcacggt
     2581 ccgttttcat tgggaaagcc atgtgaaact aacaaatgta cttgatttgg tgaatatcac
     2641 tgcacaagga tttgcatttg tggcgatcat caatttgccg gaacatgtat caagcagtga
     2701 tgtattaaaa gcaattgact ggaacaacgc ctacttgtat attgccggtg cccccatcaa
     2761 ggttactagc ggaagtttat tatcagcagg aagccatacc ttgcgttttg ggatggggtc
     2821 gtgggataca aatactctat tgacagatat tattgctatt attacgcgag gcgaattcaa
     2881 cgtggacgat atcccgcttc aatttgatgt tacagctaat gtcgcgaaga tgacagaaaa
     2941 cggagataaa tatgatacga gtccaaacaa aattttgacc aagggtaaat tacaaccttc
     3001 tatgtctaaa aaggccgttt tttctgttga tttttatgat tcgaataata ttatccaaga
     3061 tcgtatgttc aattcgattt tagctccagc tgcaggtaga ttttatccta aattaactgg
     3121 cggaaacttg aatccaggag catatgcatt ttctgcaagt gcagagataa atacgtggaa
     3181 tagttacatc tcaccaagtg attcaacagg aaaatataat acatttgctg ataccacaga
     3241 atacgtggat ggaaataacc agaaccttcc aggctctacc aatagtcgga cattgacgat
     3301 ggggctgact gaaggacgtt ttgatcagtt gccatttagt cgctttgatc gcgtagtcaa
     3361 ctattttaca ggaaaaaacg ttacacaagg agcaatactg actcatactc cagcaagcac
     3421 aagtggattg aatcagacag ccaatatcgt gtacagtggg aaagatgcgc aaggcggatt
     3481 gctttctcct gttgctttaa aggtattgga gcagtacaag ctagacggaa cggttttacc
     3541 aacaaactta acagccgata gtcagtgggg aaagctcctt tcttctgcat cgtaccaagt
     3601 cacggccaat tggtcagcaa ctgaactaaa aaagggttcg atccattaca ggctttattc
     3661 gaaaggaacc caaaaattag cgacaggatg gacagatcaa cttttccaaa cgatccaatc
     3721 aaataacggg ggtgtaaata cagctacttc tacactacct gcattggctt cagggcaata
     3781 ttattttgat tatcgcttgg tggacgatgt acttactaac atgtatccgt cttttgcgta
     3841 caaatggcag tctgaacaag ctggaatcac cactcttcct caaataacag tggctaattt
     3901 tccatctgtg agtgcagata gtcagctaaa aaaccttagc agacaacctg agacaggaga
     3961 tcccctgtct gctctatcag gagatacgat tcaagaaaat gtgacattca cgttaacaaa
     4021 atctggggat gcgataaccg acaaaaaaat cacgatctca cttcctgaaa atactactta
     4081 tatcaatggt tccttaaaat taaatggtac aactatcgca gataccggca ttcaacaagg
     4141 agtttctgtc ccagcagatc tattgagcaa aataggagat accattcatc ttacttacaa
     4201 ctatcaatta aatactgtag atacttcttt acaatccgtc agcatactga caaaggcagc
     4261 tgtactttcc agcaatatta cattagcaga tggtgctaag cttcctaacc cagttgtcca
     4321 aacatctgct aaaacaattc ttgtccccaa acaagaatta acattagtta atgtaccaga
     4381 tgattttaca tttggtaacg atctccccaa accgttgaag acaagttatt atgaatcaaa
     4441 aggcgatttt tcttttgatg tgcgggatac tcggcttcca agcacgtctc cttggcaact
     4501 gacaggtaca ttgacttctt tatttaagaa tgatcaaggt caagaattaa gcggaacaaa
     4561 attatacttc aatcattctg gatcaaagca attgattcag caaggtcaaa acacgttgat
     4621 ttatgagagt gatggaacag ctaaaggaga ggttctcgtt gactttcccg ataccgatgg
     4681 tttactctta gaggtaaata gcagtacgaa tgctcaacct ggcgcaacgt atcaaggcat
     4741 ggtcacatgg gaactgacag ctgggccaac cagctaagtg attagaattt gtatggatct
     4801 gtgataactg tcacagatcc tctttttcaa ggatgagaag gaaacttctg ctgttaaaat
     4861 cagaaatgct tgaaggagtg gacttggaac ttttcagttt gcttgaaaaa aatgaacaac
     4921 ggcaaatcaa acttttccaa cttttattag aggaaaaagg agaggtttcc gttaataacg
     4981 tacttacccg cttatcagtt gatcgggcta ccttgaaaga agatctgttt tatttacaag
     5041 ctaacttgga aaatatcaaa caattggaaa ttgttatcca agaagggaat attttattaa
     5101 tcagacatgg aaatatagca gcagtcgatg tttattatca ttgttacttg cgctattcta
     5161 caaaatatca gatacttctt tatctgttgg aaaatggctc atttgatcgg cagaaacttg
     5221 tcatggaact taatatcagt tcggctactt tgtctcgcag agtgaaggaa ttaaatgatt
     5281 ctttaaatga gtttcatctg aaaataaaaa gcgggcggct gaccggtcca gaaagtcaaa
     5341 ttcgttattt ttatttccaa ttattttggt ttggacgtcc ctatcttgaa aacaaaaaag
     5401 aatacagtga tttatcagga aacacttttt tagatctgct gcaaaaagag tttagttttg
     5461 ctattacaga agaaggacga ttgaaatttg aaatatggct ttccattatg aagaagcgaa
     5521 tgcgctgtac gaaaaaatcc aaaccagatt atagcaatct tcctgttgga ttgtttcaaa
     5581 cgacacaatt tttattggac ctccatacat ttttgacccg ttacttcttt caatatgcct
     5641 ttccttggaa tcaaaatgaa acgttggttt tttatctttt catgatcagt aactttacat
     5701 tagatacaca taactcgcat gtccaggagt ttttgataag cgaaaaatac aaagacgacg
     5761 tagtagctca attgaatcga acgtttaaac aatcgataga agaatatttc tctttttatg
     5821 tttttccaga agagatttcg caaaagattg cgttgacagt gatgcaaaat cacgctcatt
     5881 ttgcctattt tagaggatgg atgaatattt ttggccaaga aggattaaaa cagcggttaa
     5941 ctgaagtaga agataaacaa ttcctggttt tatgtgaaag attggtcaga caaacatttg
     6001 ctattgttga ttttactgaa gtagacgagg aaaatgcccg ctttgaatta tttgctcgct
     6061 atgcatctat tttacggacg ctgatcaagc agttagaatt acgtctgcaa attgcttatg
     6121 atcttcctta tgaaaggcta atggcggata tcgtgaaaga aatcatccag gaacaattgc
     6181 tgaatacgat caaatatgat ttagtcgaat acgagaaaga aaagcagtat gatatcattt
     6241 tgactagcca attgaaagag tacccgtcac agaagtccgc taaagttttt gtattcacta
     6301 gcaacgaata taattatgat ttcccctatt tgaaccaatt tttaaaagaa tgttatttag
     6361 aaaaattgaa tttaaggatg aataaaacat gaaaatcgtg atcattggtg cttcccatga
     6421 aggcatcaca gctgccctaa atctaagaaa acttcaaccg aaagcagaag ttttactgat
     6481 cgatgaagat cataaagatg gactaggcta tgtttcaaat ggaatcaacc tttatttaaa
     6541 aggaaagata cgtagtttag ctgaagttgc ccataacatg cggactcttc aagaaagtgg
     6601 ggcaaaactg atcaccgaat ggagagtaac tgaacttgat ccagacaaac atcagctcat
     6661 cctcgcatcc aaagaaggaa aaaacgagac cataacctat gataaattaa tcgtagcgac
     6721 aggttcctct cctgtcacct tgtataaaca aattgaagct gaaaatgtct acacctataa
     6781 aaatctagtg caatctaagc aagtacttgc cgctttaaaa gaagcaaaag aagtagtgat
     6841 cttcggtgct ggttacattg gattggaatt agcagatgct ttgagaaata aaggatacat
     6901 tattcatcta gttgattata tgccgaatgt tttatcaaga tatttcgata aggatatgat
     6961 caacagtttt caaaatcagc tgcaaactaa gcaaataaat ttttatccaa atgaattctt
     7021 gatcgattgg aaaaaatcag aagagaaagt agtatccgta caacttctgt ctcaaacaat
     7081 aaaggcagat atggtcattt tttctgccca aactcgtcct aatacgacat tgttaaaaga
     7141 aaaagtggct ttgtatgagg atgagactgt gatagtcaat gaatatctgc agacaagtga
     7201 tccggacatc tatgcgattg gagatatcgt cccagtcagt tttgacaaaa ataaacggca
     7261 tctcttttta cctttagtta ctcgagctgt acatatggca agagcagtag cgctaacttt
     7321 gagtggtcag ccaaccgctt acgacctcag acaaaagata acagcagcag tcattataga
     7381 ctacttttta ggaactgtag ggctgacaga agatgaagcg ccattcttgg aacaaaatac
     7441 cggttcgtgt tcaggagaat ttgatctatt tccacaatac gacgaagaaa acaaaacagt
     7501 aaatgcaaag ctgatctacc atccggatac attagaaata attggcggac agctgataag
     7561 ccaagaattc ttattatcag atttgaacct gcttgcggat atcgtgaaac acaaaactac
     7621 gattccacag ctagcagttg aggattttgg atttctgtct gaatacacct ctcgttttca
     7681 ctacctcaat gagttagctt ttaaagtact agctaagaga gcaaatagca atagagtaga
     7741 taaaagactg tgagaaatat cacggtcttt tattgtgtgg ggatataata aatattaatc
     7801 aatcgagaat aaaaaattca tataatgaaa tagcggaaga attttttgag cataatattc
     7861 gccaaaaatt tatcaagtga taaaattgtt gtataaaatg attatttcag gaggaggagt
     7921 taaatgtttt tagcattaaa tgaaattatg cattcaaagt tacgttatgc gttagttgca
     7981 ggggtgatgt ttttgatcgc ctacctggta ttttttttga ctgggttagc ttatggctta
     8041 gctcaagata atcgaacagc agtcgacaag tgggaggcag attcgattgt gctttcgaaa
     8101 gatgcaaatt caaatctagg gatgtccatg attactaaga agatagcaga agaagtcgaa
     8161 ggtgggaaag tggcgtatct tgcccaaaca cctggagtcg tgactagtaa agacagtaca
     8221 gaagaaggaa aaatcaatgt tagcttcttc ggtatcgata aaaatcaatt catcatgccc
     8281 aatcttgttg aaggaaaagc ttttgataac gatgatgagg cagtaggcga tattagtttg
     8341 aaagaagaat atggtctagc cataggagat acagttaagt tatctggtag tgacaagacg
     8401 tttaaactaa ctggctttac ggatcatgcc aaattcaatg tctcaccagt tctctataca
     8461 accatcaatg cttaccaaga aatccgcttc gaaaaagaag atacaagtga aaatgcacgg
     8521 attaacgcaa tagttgtcag aggtaaaatc agtaatttac ctgaagattt agaacagatc
     8581 aaaatttcta aattcatcaa tgaattacct ggatataatg cgcaagtatt gacttttgga
     8641 tttatgatcg gatttttgat cgttattgcg gctattgtga tcgggatttt catttatgta
     8701 ctgacgatgc aaaagattaa tatctttggt gtaatgaaag cacaagggat cacaggagga
     8761 tttattgcgc gttctgtagt ggcacaaaca ttcattttat catttgttgg tattcttctt
     8821 ggtctattag gaacagtggg aacatccctt gttctacctg atgcggttcc attccaaagc
     8881 aattggctgt tttttggcgt cattagcttg ttgatgttag tagtagctgt gttaggcgca
     8941 ctattttctg ttcggacaat cgtaaaaatc gatccgttga aggcaattgg ataagaagga
     9001 ggaagaacat gaaagcaata gaatttaaag aagtagaaaa aagtttccaa gatggcgacc
     9061 aagtagttaa agcattgaaa gaaacaacca tgagtatcga taaaggggaa tttgttgcaa
     9121 tcatcggtcc ttctggttca ggtaaaagta cttttttgac tttggcaggc ggattgcaga
     9181 cgcctagcag tggctctgta tttatcaatg atcaagaatt cagtaatcaa aaagaaagcg
     9241 aacgcgttaa actacgtttt aaagaaattg gctttatttt gcaagcttcc aatctggttc
     9301 cttttctgac agtaaaaaag cagttattat tagtagataa gattaaacat gaacatcgtc
     9361 aaaaagaagc aaacgaatta tttgagcagc ttggcgtgga taagttgatc aacaagtatc
     9421 cagaagaact atctggtgga gaacggcaaa gggtcgcaat cgctcgtgca ttgtacaatg
     9481 atccgtccat tattctagca gatgaaccaa ctgctagttt ggattcagaa aaggcacgag
     9541 aagtagtcga tatcttggca aaagaatcaa aagacaaaaa taaagcaacg atcatggtta
     9601 ctcacgatac acggctgatt gacaaatgcg atagaatatt tatgatggaa gatggtgtat
     9661 tgaaagaaaa agaataacca aaaagcaggt ggaaaaatgg tccatcgata caacaaagat
     9721 acacagcaaa aaattttgaa agaagcgact gacttgttta tgtccaaggg atatctcggc
     9781 acttcaacaa gagaaatcgc acaaaaagtt gggatcaccc agcccaatct ctatcattat
     9841 ttcggtgata aagaaaaact atatacggca gttttagaaa accacttaaa agatgttgga
     9901 aaagctttga gagaaatcgt tcaaacaagc gaaacgggat ttcaagtaac cttgacaaaa
     9961 atggcgcagt ttttgattga gacacatctg gtcgatttgt ttctgatgct tcacgatctt
    10021 gaaagcaatc tttcaaagga aacaagagat catcttttct ttctatggaa gaaaaattat
    10081 cgtgaacctt ttgaagaaat cttttcagca aaccaatctg tgctaagaaa tgggatttca
    10141 aaagaaatcg cagcaaggca ttttttctta gtgttagcac cttacatcac tcggtcgaaa
    10201 agacctgtgg aagaaccgct aaatgtggcg caattgatcg atttatattt gaatggtgta
    10261 ttaggagaag cgtaaagctg ttatataggg agaaaatagt taggtgaaga agcaagatat
    10321 gacgaagatc gttatatctt gcttctttat ataggtagtt tttcataaat acaaatttgt
    10381 tattctctca tgattatcag ggtatatttt tatttattat gtcggtgttc caggaagtgt
    10441 tttaatttaa taacgaagaa attaattgtt tgtagaatga aggaaactat ttattgggta
    10501 gatgaatcac cacgaatagt caaaaggaga tttcaggata tgccaaaaat gaaaaaaatc
    10561 attttagcag taatgttatt ttctacggtt atatctttta cagccccttt tttgcttact
    10621 taagctgatt ttaagttttg gcccttagtc tggatctacg aggtgagagt caagaatgaa
    10681 aaaaataatt ggagcttttg tatttgcaat cattatcatt attatctgtt ttcaaataga
    10741 tgtttttggt caaaaaaaga tagttggaca aacggtcagc agtacgaaca gtacggttac
    10801 aaagacaaag gaatcatttg atgatacaga acaagagaca ttaatcaaaa tcggaaaaaa
    10861 tgaccgtaca ctatatacag atgactcgct aactacccca cttgcaacta taaacggcgg
    10921 agagctggcg gagtttcttt ctgaaacaaa aaatgcttat cagatcaaga caaatgatgg
    10981 ctatactgga tatttagccc tcgaagatgg aaccaaagtc acaaagaata tacaaacaaa
    11041 accggaagag ctatctgatg cagtgattgt attagatcct gggcatggcg gaaatgatac
    11101 tggggcatta agcaatgatg aacaaacaga agaaaaagat ataacattaa gtacagccat
    11161 aaaagtaaaa aaggcgctag aggatgctgg agcaacggtt tatttgaccc atactacaga
    11221 tgaattagta cagcttggag atatatgcga ctacagtgaa gaaaaaaagg cagatgtctt
    11281 tatcagttta cacgcagact ctacggaata tgcgaatgaa gcaactggaa tcacgacata
    11341 ttattactat ggacaagagg aaacattagc acagacaatt gctgactcct tcactgatct
    11401 gcctctggat tcaagaggaa tctccactgg gaactatcaa gttcttcgag aaaatcttca
    11461 accttctatt ttaatcgaga tgggttatat gaataatgat agtgatttaa aggaattagt
    11521 aacagacagt tatcagcagc agattgctgc aagtttgaca caagcattga ccacttattt
    11581 tcagtaataa ataagcccag ccaaacaaaa atagctcctc atatttttcg tttggccggg
    11641 cttattatcg cagatgcaag cttttaaaca ccgtttaagg aagaggtcgt gagcctgccg
    11701 ttcaactctg agtcacaagg agcaatttca aaaaacagct tctcatgttt gatgactatt
    11761 gtgacttgtg accgaggagt tggcatgaga acaccgttta agaaaaaggt tgtgaaatca
    11821 acgttttgtt ctgagtatta gagaaacaaa cggaaaaata gttcctcata ttttgccgtt
    11881 tgttgagcta ataccgagga tcagatgatt gaacaccgtt tattcggaac aagggactgt
    11941 gacatgactt ttgtcacagt tccattattt ttttagtagc ttcaaagctt tttctgtatt
    12001 ggcaaaatga agtttggcat atttttcaag cataggcatg ccgcctttct ccaatagttt
    12061 tgccgctact tggtcagatt tcgttccagc tcctgacgga agggtgattc cagcttcagc
    12121 tgatgctttg tctaactctt ccaaaaagct ggcacgactg atgatagaag cagcagcaac
    12181 agctaaatga tattgttctc ctttagtaac gaagtacagt ttttcttgta attgattttt
    12241 ttctaaacgc gcatattttt taaaatttgc ttccggcgta aactgatcga tcaaaatcgc
    12301 ttctggtttt tctggctcga ttttttttag cagcaaatgg atcgcttgat tgtgcaaagc
    12361 gactttcatc cgaacggcat tgtattttgg ttggatctca ttgtattttt ctggagataa
    12421 gacaagcagt ttatagggga tggttttttt taagatgtca gcaagctgga tgatttggct
    12481 atcttttaac tcttttgaat ctctaacacc aagtttacgt aattctgcaa gctgatcacg
    12541 tttcacataa gcagcacata ctgttagcgg accgaaatag ctgccatttc cgacctcatc
    12601 actacctaaa acggataatt gactgatatt ttttggcaaa gaagaggctg tttttgctgg
    12661 cttggcttgt ttatcctgtg cctcccccca tttatcagct tctattgctg cattcgtacc
    12721 ttgaaacatc acttttccgg atgtataagc ggtaatggtc gtcccgtctt tttttgcagc
    12781 aaagctagta taaggaatct gtttatttaa caaataagag cgatagtatg ctttcatttg
    12841 actaagttgg tcgtttgttg ctttgataat gacgttgctc ataaaattct cctcgttttt
    12901 atacataaaa ctataccgca actcacgact tttcgttttc taagagattg cgagacatag
    12961 cattttttta aagtttatca tataatagtt aagtatgtga aaaatatttg tggagaacgg
    13021 tgaaagaacc aacttcatgg tacactaaat aaaactttca tcaaatagga ggaaatgatt
    13081 cgtatggcgc acgaaaaaac acgctacaaa gcggtgattg ccaaccaaac atatactatt
    13141 atcggacggg aaaccaagca tcatatggat atcgtaacga agctgatcaa tgaacagtta
    13201 gcagaattga aacaattatc accacaaatg gataatgaac aagcagcaat cttgatggct
    13261 gtcaatgcgc tttcggatca attgaagaaa caagaaagaa tattggagct ggaagaagaa
    13321 acagcagaat taaagaaaaa aatgatcaaa tttacagagc ttgaaaatcg tgtgaaacgc
    13381 attgaagcaa tcgagaacga agctcgggaa gtattgaaag aaaatggtca agcagatcat
    13441 accattaaaa atcatgtgga agcacaacag attttaaacg agaaacgaaa aggacaaatt
    13501 aaacaaaaat cttctaatta agatcctttt atcaaaataa gaaaaattta aaaaagttag
    13561 aagagaaagg aacgtagcat gctgagtttg ctgattttat ttttattgct aattgcgttt
    13621 ttttctggag cacgtcgcgg gtttgctttg caaatcatat tcgcgattgg atatgtattg
    13681 tcatttattg ctgcccagca tttttacaaa ccattagcaa gtcatttgga attatacatt
    13741 ccatacccag ctgtcacccc aacatcaaag ttagcatttt ttgatcaggt atttgccttt
    13801 cacctagatg aagcttttta tgcaggaact gcttttctga ttattttgct aattggctgg
    13861 ctgcttaccc gatttgtggg ggtttttgtc catggattga cgtatgtgcc gatcttgaga
    13921 caggtagact ggattgcagg aggcatcctg tcactaatca tggcttacgt tactatattt
    13981 ttgattttgc agttacttgc ctttgttcca ttagatgtgg tccaaaatca attcggcgag
    14041 catagtttcg ctcgttttat cgttgagaga acgccatttc ttaccaacaa gatgtatgag
    14101 ctttgggtaa cgaatatttt gaattaagga aaatagtgct ggaaaatatt tcgttttttg
    14161 tacagagtag tttatttaag aaggctgcgt agcgtatgtc cggcacagct cttttttcat
    14221 agtgaaagat aaggtgataa aatgaataac cgaatccttg aaacattgga atttgaaaaa
    14281 gtcaaacaga tggtcagaca atttgtagtg actgcacaag gaaaagaaga actggcagaa
    14341 ttggtaccag tgagtgagaa acaaacgatc acaaactggc ttcaagaaac tgaggatgga
    14401 ttgaaagtgc aacgtctgcg aggcgggatc cctataccta aaattgaaaa tatccgtccc
    14461 catatgaaac ggattgagat cggagcagac ttgaatggag tggagcttgc acaagtttcc
    14521 agagtattgt ctacgacaag cgaattgaat cgtttcattg atgatctttc tgacagtgaa
    14581 atcgaatttg cacgtttgta tatgtgggca gatcagttag tcacgatccc tgttttgagc
    14641 cgccgtttaa aggaagcaat cgatgaagac ggacgcgtga ctgatgacgc ttctcctgag
    14701 ttaaagagca taagacagaa cattcggcga agtgaacaag ctgttcgtga acagttagat
    14761 gggatcgtcc gtgggaaaaa tgcaaagtat ttaagtgatg cgatcatcac catgcgaaat
    14821 gaccgctacg ttatcccagt caaacaagaa taccgcggtg tatttggcgg tgtagtccac
    14881 gatcaaagtg cttcaggtca gactttattt attgaaccaa aacaagtggt ggatttgaat
    14941 aatcgtttgc gtcaatacca aatcgctgaa cgaaatgaga ttcaacgtat tttaagtgaa
    15001 ctttctgctg aacttgttcc ccatcgtcaa gaaatcatcc acaatactta tgtgattggt
    15061 aaaatggatc tgatgaatgc aaaagcacga tttggtaaag aagtaaaagc catcgtgccg
    15121 ggaatcagtg aagacaatca tgtcgtcttg aaacaagcaa gacatccact gatcgatcag
    15181 gaaaaagtag tttctaatga catcacaatc ggaaaagact atcaagccat cgtcattaca
    15241 ggacctaaca caggtgggaa aacgatcacg ttgaagactt taggtctgtt acaactgatg
    15301 gggcaagcag gattaccgat tcctgcaggt gaagaaagtc aaatcggtat ttttgaggaa
    15361 gtatttgcgg atataggaga cgaacagtcg attgagcaaa gtctatcgac cttttcttct
    15421 catatgacga acactgtaga tattttatca aaagtcaatg aaaaaagtct ggtattattt
    15481 gacgagctcg gtgcaggaac agatccgcaa gaaggtgctg ctctagcaat cgcaatctta
    15541 gatgatcttg gtaaaaagtc tgcttatgtg atggcaacaa cgcattatcc tgaattgaaa
    15601 gtttatggat ataatcgggc aaatacgatt aatgccagca tggagtttga tgtggataca
    15661 ttaagtccaa cgtatcgttt gctgattggc gttcctggac gaagcaatgc gtttgaaatc
    15721 tctagccgat taggtcttga tacagaagtt attgatgaag cgaagcagtt gatgaatgat
    15781 gagagccaag atttaaacga aatgatcaca gatttagaga atcgccggaa aatggcagag
    15841 accgaatatc tggaaatgcg tcattttgtt tctgaggcac aagaacttca cgatgatttg
    15901 aaagaagctt acagctattt ctttgaagaa cgtgaaaaag aaatggaaaa agcaaagaaa
    15961 aaagcaaatg aagtcgtgtc agaggcggaa gaaaaagcag aaaaaatcat tgctgatatt
    16021 cgtaaaatgc aacagcagat tgggcaagga aatgtgaaag agcatcagtt gatcgatgca
    16081 aagacccaat tagcaaatct acatcaagaa gaaactttga agaaaaataa agtattgaag
    16141 aaggcgaaag aacaaaaaac gttgaaaccg ggagacgaag tgttggttac gacttacggc
    16201 caaagaggga cgcttttacg taaaaacggg aatcagtggc aagtagaaat cggtatatta
    16261 aaaatgaatg tgtccgaaga cgagctgacg cctgttgctc ctcaaaaaga gccgacacaa
    16321 cgagttatcc atgctgtacg atctgaatct agtagtcacg tgccgaatca attggacctt
    16381 cgaggaaaac gatacgaaga agcgctaagt gaggtagatc aatatttgga ttctgccatt
    16441 ctagctggtt atcctcaagt gactattgtc cacggaaaag gaacaggcgc acttcgcaag
    16501 ggaattactg attatcttaa aaaccatcgg agcgtcaaaa gctttgagtt tgcaccggca
    16561 aaccaaggcg gaaatggtgc gacaattgtt aaatttaagt aaagcttact aaaggtaagc
    16621 agatggttcg ctatccaagt atagaaatgc tatactagtc atagatttta aaaatggagg
    16681 tctttgatat gtcacaagta attacagata agacatttaa tgaagaaaca gataaaggac
    16741 ttgtattgat tgatttttgg gcaacttggt gtggtccatg tcgtatgcaa gcaccgattt
    16801 tggatcagtt ggaacaagaa tatgatgaag aagaattcag aattgctaaa atggatgtgg
    16861 atgaaaatcc agaaactcct caacaattcg gtatcatgag cattccaaca ttaatgttga
    16921 aaaaagatgg tcaagtagta gaaaaagctg ttggtgttca ttcaaaagaa caactacgtc
    16981 aaatgatcga tcaatattta taaaaactta cagcaaaaat aagctgaggg tgggactgaa
    17041 tccagttccg tcctcggttt ttttgcggtt gagttaaggt tattcaaatt aatatttttt
    17101 gagtataatt acgttgtcag gctggattgt ttttttgaca gacatgctat aataacttta
    17161 attgaatatg aaggggagta ccagatgaac gaacgaatca aaaacaaatt agctttactt
    17221 cctgatcagc ccggctgtta cttgatgaaa gataaaaatg gaacgatcat ttatgtcggc
    17281 aaagccaaaa tattaaaaaa tcgtgtccgc tcatatttta ctggtagcca taatacgaaa
    17341 acggaacggc ttgttagtga aatcgaagac tttgaataca tcgttacaga atcgaatatc
    17401 gaagcattgc tcttagagat caatctgata aagaaaaatg atcctaaata caacattatg
    17461 ttaaaggatg ataaaaccta tcctttcctt aagataacga atgaaaaata tccccgtttg
    17521 gtgattactc gtaaggtact aaaagacaaa gcactgtatt ttggaccata tcccgatgtc
    17581 ggtgcggcga atgagacaaa gaagatcctc gatcgattat ttcctctgag aaaatgcaaa
    17641 cctagtcaga cgaaggagcc ttgtctttac tatcatttgg gacaatgcct gtgtccttat
    17701 tatttcgacg tagatccgaa agtctatacg aaaatcgttg atgaagtgaa aaacttttta
    17761 aacggaggac acgaaaaaat cgagtcagag atccatcaga aaatggaaaa agctgctgaa
    17821 aacatggagt ttgaaaaagc tgcagaatac cgagaccaga tccgtgccat tgagacaatc
    17881 atgactcgcc aaaaaatgac aaatactgat ttactggatc gagatgtatt tggttatgcg
    17941 attgataaag gatggatgtg tgtccaagtg tttttcgtaa gacaaggaaa gctaattgaa
    18001 cgagatgttt caatgtttcc tttctataac gaagcagaag aagatttctt gacttacctc
    18061 ggtcagtttt atcaggaaaa tgagcatttc attcctaaag aagtcttgat tcctgatacg
    18121 atcgacaagc ccagtgtaga agctttgtta gctacgaaag tgctgcaacc aaaacgagga
    18181 gaaaagaaaa aattagttga attggcgagt aagaatgcct cagttgcttt gaatgaacgg
    18241 tttgatctga ttgccagaaa acaggaacgg acgatcggag cagttgaacg tttaggaaac
    18301 gcgatgaata tcccgacccc aatacgtatc gagtcttttg ataactctaa tatcatgggg
    18361 acgaatcctg tggctgcgat ggtcgtattc attgatggaa aaccggcaag aaaagaatat
    18421 cggaaatata aaataaaaac agtcaacgga ccggatgatt atgcatcaat gagagaagtc
    18481 atctatcgca gatattcgcg agtgattcgc gaagggttgc ctttacctga tttgatcttg
    18541 atcgatggag gaaaaggaca agtagatgtg gcaaaagatg tcttagaaaa tcaattagga
    18601 atcgatattc ctattgctgg catggtaaaa aacgataaac ataaaacaaa tgagttgcta
    18661 ttcggtacag atttggctgt agtaccgctt gagcgaaatt caccagagtt tttcttactc
    18721 cagcgaatcc aagatgaagt ccatcgattc gcaatcactt tccatcggca gctacgcagt
    18781 aaaaacagtt ttgcttcccg attagatgaa attgaagggt taggaccaaa acgaaaaaaa
    18841 atgctgctta aagagttcaa atcgttgaaa aatatcacag cagccacgac agaagaatta
    18901 caagaaatcg gactgccgaa aaatgtcgca caaaacgtat ttgataaatt acatcaggaa
    18961 tgaggaaagg gcactttaca aagaaagtaa agtgtcctat cattttatgt acaacaaaaa
    19021 gagcgtttac gttttgttgg taaataataa atcgcttacg tctggtgtct aaggatatat
    19081 gtgatttctt gaagaaggag tgaagaaatg ttagaagtca aggatcttgt taaaactttt
    19141 gggaactaca cagctgtcga tcatgtctct ttccaaatcc ccgatggaaa aatcatgggg
    19201 ctaattggcc aaaacggggc tgggaagaca acgacttttc gtttgatctt ggattttttg
    19261 acacaagacc aaggagaagt gttatggaat ggccatcatc ttggggagaa agattatgat
    19321 gtcatcggtt atcttccgga ggaacgggga ctttatccga aagtaacgat tcaagaccaa
    19381 ctgctttatt ttgcagaact tagagggaaa tcaagaaaag agattgaacc aaaaatcgac
    19441 ttttggatgg aaaaatttca ggtaaaaggg aaaaagacgg ataaagtaaa atctttgtct
    19501 aaaggaaatc agcaaaaagt ccagctgatc gccacgttaa tccatgaacc taaattgatc
    19561 attttggatg agccattcag cgggttagat ccggtaaatg ctgaattgct aaaagatgga
    19621 atattggaat tgaaaaaaca tggttcatgt gtcatttttt ctagccacaa tatggataat
    19681 gtagaaaaaa tctgcgatca tttgatcatg ttgcgaaacg gaaaaatggt tttgaatgga
    19741 aaagtacatg agattcgtga atcatttggc cgtacgaagt tattcttgga atctggttta
    19801 agccaacagg aagtagaaga aatcgaaggc gtgaaaaaag tgatccttca tgaagacaat
    19861 acgttagaga ttaccttaga agatcctgaa gctgggaaag aaatctttac tcgtgcgact
    19921 cagttcggct acattcctat gtttaaccag caaccgccaa ctttggaaga gattttcaaa
    19981 ttgaaagcag gtgaaatcga tgcgtaagtt ttggattatt accaaagatg tctatttaaa
    20041 aaatgttaag tcgatttctt tcttgatcat gatattagtc ccttttatca tgctgggtat
    20101 catttatgta gcaggaaact ttgctcaaca aaatagtgat gtcaataaaa tcggcgtatt
    20161 ggctgataat gagcaaatca gtcagcaaat gagccaagtc aaaacagatg attttgagtt
    20221 caaagcagtt gattctgaag aaaaagcaca aaaagagctt tcggaagaaa aaatcgatgc
    20281 gtatttagta gtctcaactg agaatgataa gataaatggg atgctttata gcgaaaattc
    20341 attaggacaa agtacacaac tactgataca acaacaactg actggcttgc aatcgatgct
    20401 tcgagcgagt caattaggca tttcaccaga agaagtagct agcttgagcc aacaagcaag
    20461 tttgactcga caaaaagtca attttgattc aaaaggaaaa atgacagtcg gagaagataa
    20521 ctcgacagtc caatacgtcg taagttatgt agcaacgatt gtcttgttca ttattatttt
    20581 gacgtatgcg cagatcattg cacaagagat cgcttctgaa aaaggcacgc ggatcatgga
    20641 agtgatcctg tccagtacga ctgcacaaaa gcatttttac ggaaaattaa caggtgtttt
    20701 acttgttgca ttaacgcaaa tggcattata cggtattatt tttggtatag gatacagtca
    20761 attcaaagat atggaaatgg tcaaaaatat attagacggt atctcattgg ataacttgat
    20821 tggaccattc ttgtggtatt ctcttctatt catgatcttt ggcattttga ttttttctgt
    20881 tttagcagct ttatgtggct ctttggtcaa caaagcagaa gatacagcaa aagcaatttt
    20941 gccagtgact tatctatctc taggcggata catgcttgga ttgatactag gagcttcaga
    21001 tccaaacaat atcgttattc ggatcacttc gtatattcca ttcttatctt catatattat
    21061 gccgattcgc ttagcaaatg agacagtcgg tatgggtgga gcattgattt ccttgttggt
    21121 acttgtagcc gtaacattct tattgatgat cttgtctgca aacatgtaca aatcgaatgt
    21181 actcgtttat agcgaaggcg gattatggag ttcattgaaa caatcgattt caattatgag
    21241 gaatgaacga aaaaaagcat aaaacaatcc taaaatacag aaggaagctg gacatctatt
    21301 gttcccagct tctttttgta tagacctatt ttatttattt tactatattg gatatatatt
    21361 cattgaaaat agtgtataac aactttataa tattgagtat accaattttt ggaggcgttt
    21421 taatggaccg ttatttagat ttactttcag aaaaattccc ctcaacggag gatgtcatca
    21481 cggaaatcat caatctcgaa gcaattttgc agcttccaaa aggaacagag ttatttttga
    21541 gtgatataca tggcgaattt cctgcttttg atcatattct gcgtatcggt tcaggaaatc
    21601 ttaaagaaaa gatcaaagac cttttttctg aacaaatgac ggaaacggat atcagccaat
    21661 tcactatttt tacggcttat ccagaatatg cattaacgac tgattggtac aaagaacaag
    21721 ataaatcgca gctgatccat catttgatcg atcttttacg gtttacgaca gtcaaatata
    21781 cccggtcaaa agttcgaaaa ggattgccga aagaatatag ctatatcatt gaggaactct
    21841 tgtatatcga tgaccgtatc aatggaaaaa aagactatgt aaaaaaaatc attgaacaac
    21901 ttgttttgat gaaggaagaa gaaaaatttt taacgaaact tgcacagacg atccaaaaat
    21961 ctgtcatcga tcatttgcat atcgttggag atatttttga ccgaggaact caagcagcca
    22021 aagtgatgga tcgaatcatg gatttttctt ctgtagatat ccaatgggga aatcatgata
    22081 ttttgtggat tggtgcgtat tgcggctctg aggcatgttt actgacactt ttacggattg
    22141 cagcacgcta taattattta tttgaattag agaaagaata tgggttgaat ttacgtccat
    22201 tgttttcttt tgctcatcaa acttatcaga agaatccagt atttgcgcct aaaaacagta
    22261 aaaatctatc cgaaagagag caagaagaat tagaaaaaat ccatcaggca ctttctatcc
    22321 ttcaattcaa atcagaacat cagttattgg atcgtcgacc tgaatttaaa atggacgatc
    22381 gtaaattgct ggaaaaaatc gactatgaag catcaacgat tgatttagaa ggtcagctct
    22441 atgagttgaa aggaacttgt tttcaaacga tccagccaga tgatccaaaa aaaatcttgg
    22501 aagaggaaca aaaagtgatt gatagtttga tgtattcatt ccagcactct ttgagaatgc
    22561 aaaaacatat gacgtttttg atcgaaaaag ggggaatgta tctcacgaac aatcagcatg
    22621 tgctgtttca tggctgtata cctgtagacg agaagggaca gctcttagca tttgaattag
    22681 accaatctta tcgcggaaaa gaactgctgg gcttttttga aaaacagata actgaaagcg
    22741 caaaagatct gactgcaaaa gaagatttag caaccgattt gatttggtat gcgtggagtg
    22801 ggccattttc gcctttattc ggcaagagta aaatggcgac ttttgaacgt tattttctca
    22861 cagagcctca tacgcacgtc gagaaaagca atccttatta tcacttgcga gatgaagagt
    22921 ggttcagtga aaaaatttta gcagaattcg acacaaaaga agaagggtca gcaatcatta
    22981 atgggcacac gccagtaaaa gtaaaaaaag gggagtcacc gatcaaagca aatggaaaag
    23041 tatttgtcat tgacggaggt ttatccaaag cttatcaaaa aacgacagga attgccggtt
    23101 attcactatt atgcaattct tatggtttcc aaatcgtgac acattatccg tttttgccta
    23161 ttgaacaaca atttgcaaaa aaatccgacc aaacaaatgt gaaaaaagta atcgaacagc
    23221 aactaccacg caaactcaat cgtgatacaa caaaaggtat ggaactgcag cagcagatta
    23281 cccagctcaa aaggctgttg gactatcgaa aggacgattg agaagaattc cagtgaacat
    23341 tgttccatag actggagact gagacaaaag tcgtgtcgca gtctcttttt ccggataaac
    23401 ggtgttcttc tgccaactcc tcggtcacaa gtcacactat tcaacaaaca tgaaaagctg
    23461 ttttttgaaa ttgctccttg tgactcagag ttgaacggca ggctcacgac ctcttggtat
    23521 aaacggtgtt caaaagccag tttctcggta ttaagccaaa tttatgcaaa aatgtgaaaa
    23581 gccattttca caaaattttt cttaatactc gaaactaaac agctttttca caaccccctc
    23641 agaaagtcta ttaaaattca ttcacaaaga aatcgaataa gcgctgttca gatggatgta
    23701 cacggtgggt aagttccgga tgccattgaa caccgaggat tttatgcata tcatctttgc
    23761 tttgaaccgc ttcaacgagt ccatcgttag aaaaagcgat ggcttttaat aaaggtgaaa
    23821 gatctttgac tgcctgatga tggtaagaat tcacaaaata tggatcgggg agaaggttgc
    23881 ttaacaaact gtctgaaaca atcttgactt cgtgagtcgt aaattgcggg gcagtgggct
    23941 gttgttcatg ttttactgac cactttggat ataatgaaag atcttgataa agtgtacctt
    24001 ccaaaacgac attcaatagt tggagtcccc ggcagactgc aaaaattggt tttctttgtt
    24061 tcaatgcttc caagatcagt gcctgttcaa attggtctcg ttgaatattt gttccgttag
    24121 ctttggatga ggatcttcca tgtaaagttg tggactgaca tcttgaccac ctgcaagaat
    24181 aagtttgtcg atttgtccaa tcagttgagg agctgaatct ggagacatga ctggcagaat
    24241 aagaggcaat ccttgagcat ctaaaactgc atccacgaat ccttgcggtg tatagctcac
    24301 ttgatttcct tggaaagtat ctgttgctcg aatcagttga tttccggcaa tgccgatgat
    24361 tggtttcatt tgtattcccc ctaaagtaga cttattgtaa caaggattta aaaaaaatta
    24421 aactatgtaa gacttgcccc tatacttatc tgttcttgct gtgttactat ctgtaaagag
    24481 aaatttcgtg tgaaattcat gacgatagtt gaaaatattg cttaatttgt tataataaaa
    24541 agtaagcaga aataaaaagg ttgggcgtaa gcttcaagga tctagttctt caaggggtga
    24601 gaaggacatt ttattgaagg ggcctgccta tactaagtta tctttagagg tacatacttt
    24661 caatgaaaaa agaaagcatg tacctctttt ttaaatcgaa aggaagtgaa gcaagtgtta
    24721 gaagctttgg aacaaatccg aaaagcagaa gaagaaaatg aaaagcgtgc tcaaacactg
    24781 cggcagcagc tgaagatcta tgcaacagaa aaagagcagg aattggaaac gatccaaaca
    24841 aactatcgac aacaactaaa acagttggtg gaagaaaaag aacaatttga aatacaagaa
    24901 ttagaaaaag aaaaaatgaa attgaaagca gaagcagaca aggtgcaagc aactttgaaa
    24961 gatcaatatc aaaagcatca gagtcaagcg atcggtgcga tcattgaaag ggtgaaagaa
    25021 acttatggcc gtcactaaga tggaaaaagt gaccctcatt tcagataaaa gaaatcagga
    25081 gaggatttta caagcagtac aaggaatcca aaacgttgaa atccgggatc tgtatcaaaa
    25141 tagaacaaac aaccagtggg tggagaagta ttttccagat accacgatta ttgataaaga
    25201 agcaaaatta agcgctttag gtaatcggtt gaaagacatc caagaagcta tccaattcat
    25261 acaacaccac ggcgatagcc gtcaaaagaa actccatttg aaacgtcaag aactttcctt
    25321 acaagatttg gaagccaatt attccgaaga aaatttcata aataaattga aagaagtcct
    25381 tgatttaaaa gaaaagtggg aacaactaac tgaagaacgt gatcgtttag aagaagagga
    25441 agaatggctt cttcattggc aacagctgga tattgctcca agtatgtatg caagtaagac
    25501 gaccattttt gagatgggga ctgtgagtgc agcaaatttt gaaagtttca aggaagaact
    25561 gagtaagctt gatgacgttt atatggaaga aatagattat acgccaaaac aagtttatct
    25621 ttcgtatgtt gctttaaaaa aatcagttgc tgttatagaa gaaattgctg ggaaatacgg
    25681 gttcaataaa gaaacgtatc cttatgaaca aaatcctaaa gaaaaactgc aagagaccaa
    25741 gcagcaatta tccattgttc acgagcagca aaagaagata acgacagcgt taggtcagtg
    25801 cagtggctat atccaagaat ttgaatgggt agaagaagtc acacttgccg ttgcagaacg
    25861 agaaaaaata aaagaacggt ttatccatgc gacttatctg atcgttttgc aaggttgggt
    25921 agatgcagaa gaaaaacaga atttgctgca tgtgttaaac gaaaccgtat cagaagaaga
    25981 tatatacgtc agtttcgaaa caccaaactc agaagagatt cagcaggaag tccctactaa
    26041 attgaaaaac catccgcttg tcgaaccttt tgaattgctg actgaaatgt acagtctgcc
    26101 aaaatatgaa gaagtagatc caacaccttg gatgacacca ttttatcttg tcttcttcgg
    26161 gatgatggtc gcagatgttg gttatggttt gctgatgctc attgggacaa tactagctca
    26221 aaaactactt gttctaccac gcgggatgaa acgtttcgta aaattctttg agattctctc
    26281 gataccatcg atcatctggg gattgatcta cagttcattt ttcggacagt cattaccaaa
    26341 agaactgttt ggcatccgct tgcctttccc aatcctatct acgacggatg acgtcaatac
    26401 gattttgatt ttatccgtga ttttcggtct gatacagatt ttggttggat tatttgtggc
    26461 agcaaaggaa aatatcagga gaaaagatta cttgagtgct gtcagtgatg gatttgcctg
    26521 gcaagggatc ctaattggga tcgttattgc gttggttggt gccatgttga taaaaaatac
    26581 agcatttgtt taccttggcg ctgggctatc gatcattgct gccttatgta tcttgatcgt
    26641 tccgattatc caaacgccgt ctaaagtcaa aggtgctgcc aaaggtgcgt ataatcttta
    26701 cggactgacc ggctatatcg gtgatttagt cagttataca cgtttgatgg cattgggtat
    26761 ttcaggcgga agtattggag cggcattcaa tatgctagtt gctttcatgc cgccagctgc
    26821 tcgattcagt gtagggatcc ttttgatcat cgctttacac gcactgaata tgtttttgac
    26881 actgctaagt gcctatgtcc atggcgcacg attgcagtat gtcgaatttt ttgggaagtt
    26941 ttatacagga ggcggacgtg cctttgatcc gctgaaaacg gcggaaaaat acgtcaacat
    27001 caatcacaag aaaaaaaaca ataaataatt ggaggatttt tatataatga tggattactt
    27061 aattagtcaa aatggtggaa tggtatttgc ggtattagcg atggcaacag cgacgatttt
    27121 ttcagggatc ggttcagcta aaggtgttgg aatgacaggt gaggcagcag cagcattgac
    27181 aacaagtcaa cccgaaaaat tcgggcaggc tctgattctg caattgcttc caggcacgca
    27241 aggtttgtat ggattcgtta ttgccttttt gatttttatc aacttaggaa atgacatgtc
    27301 agttgtacaa ggactgaact ttctaggtgc ttctctgccg attgctttta caggcttgtt
    27361 ttcaggtatt gcccaaggaa aagtcgcagc ggcaggtatt caaattttag cgaaaaaacc
    27421 tgaacatgct acaaaaggaa tcatttttgc tgcgatggtt gaaacatacg cgattttagg
    27481 tttcgttatt tccttcctat tagtgttgaa tgcctaagca taaaggagga aaagcagatg
    27541 aacgccattg aaaaaatcat ctctcagatg aacgaagcag cagagcagga aagagcggcg
    27601 ttagaacaag aagagcgaat gaagatcgat caaaactttg aacaaaaacg tacgcaagtt
    27661 gaaacagaac atcaaaaaca aaaagaaaaa caaatcgaat tactcgaaaa aaaataccgt
    27721 cagctaagga atcgccagca agtagaagta cgacaagaaa atttgaatgc gaagcaggaa
    27781 tttttaagac gattgtttgc agatgcggta actgaaatgg aaaattggga tgaatctgaa
    27841 caaatccagt ttatcaaaaa tgcattgtat tcattacctt tgacaggaaa agtagcattc
    27901 attgctggag aaaaatcagc agcctatctt tctcagacgt tgttggatga atggaacaat
    27961 gaacttccct ttatgatggt tttaagtgat gaaactgttg ctgatcaagc gggttttctg
    28021 ataaacgatc aaggagttca gtataatttt cttttcagca gccttgtaca agatatccaa
    28081 ggaacgatga gttttgagat tgccaatcaa ttattcgaat aaggagggat cagtgtatgg
    28141 aataccacga actaaatccc ttgattcgcg gaagagagct tgaacttttg tccaatgaga
    28201 catttgaacg gatgattcaa acaaattctg tcgaagcact tggtgaaata ttgaaatcca
    28261 cgatttacag tccatatatt tatgacggat atgaatatga cttcgaacag aatcttttaa
    28321 aggagcagag ccgtctattt cgctggttaa aggaatcagc accggagcct gaaatcgttt
    28381 ggatctatac gatgcgttat actttccata atctgaaggt tttgacaaaa gctgagatga
    28441 caaatcaaaa tctggaccat ttgtatatcg acgatggatt ttattcatta gaaaccttga
    28501 aggatgccat tcatacgcaa gtttcaaatg aacttcctga aagcattatg gacagtatac
    28561 gagaagtacg tgattatttt gaagagtcta ccattcttca gggaattgac gtgatttatg
    28621 atcgacagtt tttgacagag cagcgacggc ttgccgataa gctaggatat caagaattgc
    28681 tgacagaagt cattgctttt attgacttga ccaatatcac aacgatggct cgaggaatat
    28741 tgcagaaaag aacatatggg ttcatgacga cggtactttc cagctcggga agtatcgaaa
    28801 aagaagtatt tttgaacttt gtagataaag atatggaaga ttacacgaat tttctattag
    28861 agacagatta tgctgatttt ctgcgccctg tcatccgtga gggaaatatt gatctcgtaa
    28921 agcttgaaca gttgaaagat gattatctaa gttcattgta tcaagaagca caaacccagg
    28981 ctttcggacc actgccacta ctagcctttt tgaacgcaaa agaggtagaa agcaaaaacc
    29041 ttcgtttact ggttatcggc aaaagaagcc atttcgaatc agaaacaatc agaaagcggg
    29101 tgagacaagt ctatgacgca taagatcggt gtagttggcg acaaagattc tgttttgcca
    29161 ttcaaattgt ttggctttga tgttcgttat ggtacaacca agcaaaccgt tcgtcaggca
    29221 attgaagaaa tggcaaagaa tgagtatggc gtgatttatg tcacagagca atgtgcagca
    29281 ttgagcccag aaacgatcga acgttacaag gaacaaatga tacctgctat cgtattgatt
    29341 cccaatcatc aaggatcatt agggataggg ctggaagaaa ttcaaaaaaa cgtagaaaaa
    29401 gcagtaggtc aaaatatctt atagtatgaa aaggagatag aaattttgca aattggaaaa
    29461 atcataaaag tctccggacc tcttgtaatg gctgagaaca tgtctgatgc cagtatccaa
    29521 gacatgtgtc tagtgggaga tctaggagtt atcggagaaa ttatcgagat gcgtggcgat
    29581 gtggcgtcta ttcaagtata tgaagagact tctggaattg gtccaggcga accggttcgc
    29641 tctactggtg aagctttatc tgttgaatta ggaccaggga tcatttcaca aatgtttgac
    29701 ggaatccaac ggccattaga tacctttatg gaaatcacac aaagtaattt cttagggcgc
    29761 ggagttcaat tgcccgcatt ggaccatgag aaaaaatggt ggttcgaacc aacagtagaa
    29821 gccggagaaa cggtgagtgc tggagatgtt atcgggatcg tagaagaaac aaaagttata
    29881 aaacataaaa tcatggtgcc aaatgggata aaaggaacga tcaaaacaat cgaaaaaggt
    29941 tcattcacta ttgatgaaac agtatgtgtc attgaaaccg aaaatggtga caaaaatttg
    30001 acgatgcttc aaaaatggcc agtaagacgt agtcggccaa tcaaagaaaa attaaacccg
    30061 gatgcaccca tgatcactgg acagcgagtg attgatacat tcttcccagt gacaaaagga
    30121 ggagcagcag ctgtacctgg tccttttggt gcagggaaaa cagtcgttca gcatcaaatt
    30181 gcaaaatggg ccgatgtgga catggttgtc tatgtgggat gtggcgagcg tggaaatgag
    30241 atgacggatg ttttaaatga attccctgaa ttgattgacc ctaatacagg agaatcgttg
    30301 atggaacgta cggtattgat tgctaataca tcaaacatgc cagtagcagc tcgagaagct
    30361 tctatctata cgggaatcac aattgcggaa tatttccgtg acatgggtta tgacgttgct
    30421 atcatggcag actccacttc acgatgggca gaagcacttc gtgagatgag cggacgtttg
    30481 gaagaaatgc ctggtgatga aggttatcca gcttatcttg gttcacggct tgcggaatac
    30541 tatgaacgat ctggaagagt cattgcatta ggatcagaag gtcgcgaagg aagtataacc
    30601 gcaatcagtg ctgtatcccc gtctggaggg gatatttcgg aaccagtcac acaaaataca
    30661 ttgcgggtcg taaaagtatt ctggggtctt gattccagtt tagcccaaaa aagacatttt
    30721 ccttcgatcg attggataca aagctattct ctttattcaa cagaagtagg gaagtatatg
    30781 gatcatatcc ttcaagctga ctgggcatcc atggtcaccg agggcatgcg tattttgcag
    30841 gaagaacagc agctgaatga aatcgtgcgt ttggtaggga ttgattccct ttcagataat
    30901 gaccgtctga cattagaagt ggcaaaatcc attcgtgaag attatttgca gcaaaatgct
    30961 tttgatgatg tcgatacatt cacttcaaga gagaaacaat tcaaaatgtt gaagatgatc
    31021 ttgacctttg gtgaagaagg acgccgtgcg ttgtcgttag gtgcttattt aagtgagatc
    31081 atggacggta ccgtatcgat tcgtgaaagg atcggacgaa gcaaatatat cccggaaaca
    31141 gaattagaaa aactagatca aattattggt gaaatcaagc aaacgatgca aacgatcgtt
    31201 tcagaaggag gcatgagcaa tgattaaaga atatcgtacg atcggtgaag tcgtcggtcc
    31261 attgatggcg gttgaaaaag ttgctggtgt caaatatgaa gaattaatcg aagtccgtat
    31321 gcaaaatggc gagattcgtc gtggacaagt attggaagtc caagaagata aagcaatggt
    31381 ccaaatattc gaaggaacaa gtggtatcaa tttacgtgac tcttctgtac gatttttagg
    31441 ccatccttta gaactaggtg tatcggaaga catgatcggt cgagtattcg atggtttggg
    31501 acgaccgaaa gataacggac cagagatcct gcctgaaaag catttggata ttaacggaga
    31561 agtaatcaat ccagtagctc gggattatcc agatgagttt atccaaacag gtatctctgc
    31621 aatcgatcat ttgaatacat tagttcgtgg gcaaaaatta ccagtatttt ctggctctgg
    31681 tcttcctcat aaagaattag ctgctcagat cgcgcgacaa gcaacggtac tcgattcatc
    31741 agatgatttc gccgtagtct ttgctgctat tggaatcact tttgaagaag ctgaattttt
    31801 catggaagat tttcgtcaaa cgggcgcaat cgaccgttct gtcatgttta tgaatttagc
    31861 aaacgaccct gcaatcgaac gtatcgctac tcctcgtatg gctttgactg ctgcagaata
    31921 tcttgcttat gaaaagggaa tgcatgtttt ggttatcatg acagacatga ccaactatgc
    31981 agaggcattg cgagagattt ctgcagcacg gcgagaagtt ccaggaagaa gaggatatcc
    32041 tgggtatctt tacacgaact tagctacttt attcgaacga gcaggaagaa tccgcggact
    32101 aaaaggatcg gttactcaaa ttccgattct aacaatgcca gaagacgata aaactcatcc
    32161 aatccctgac ttgactggtt atattacaga aggacagatc atcttgacta gagagcttta
    32221 caagagtggg attcagccac caattgatgt actcccgtct ctttcgcggt taaaagataa
    32281 gggaactgga cccggaaaga caagagaaga ccatgcagct acgatgaatc agctttttgc
    32341 agcctatgca caaggaaaac aggcaaaaga attagccgta gttttaggtg aatctgcttt
    32401 atctgatgta gacaagatct atgcgaagtt tgctgagcgg tttgaaaaag aatatgtcaa
    32461 tcaaggattc tacacgaacc gttcgattac tgaaacactt gatctagggt gggaactgct
    32521 atcgatgttg ccaagaaccg aattaaaacg aatcaaagac gacatgctgg acaaatatct
    32581 gccagaaggg aagtgagttc tgatggcacg attgaatgtg aatccgaccc gcatggaatt
    32641 gactcgattg aaaaaacagt tgacaactgc cacaagaggg cataaattat taaaagataa
    32701 gcaagatgaa ctgatgcgtc aattcatcct gttgattcga aagaacaacc agctgcgtca
    32761 agaaatggaa gagtctatga cagaagcaat gtctgatttt gtattggcaa atgcttcgat
    32821 cacggaacct ttcatcgaag aattatttgt tttgccggcg gaaaacgttg atttgtctat
    32881 cgtagacaaa aatatcatga gtgtaaaagt acctgtgatg aattttgaat atgatgaaca
    32941 gctgacagac acacctttgg aatacgggta tttgaattcc agtgccgaac tggatcggtc
    33001 aatcgatcgg tttactaccc tgcttccaaa acttttggaa ctgacagaaa tcgaaaaaac
    33061 ttgtcaactg atggcgagtg aaatcgaaaa gacacgtcgg cgagtcaatg cattagaata
    33121 tatgacgatc cctcaattag aagaaacgat ctattatatt cgtatgaagc tggaagaaaa
    33181 cgagcgcgca gaagtaacaa ggttgatcaa agtaaaaaat atgggtacca ctgactaagt
    33241 ggtatctttt tttaaaagag gaaaacgatg attaaacaaa gcaaacaaat aaagaaacgt
    33301 ttgccggctg ttcagcttct cgcattagga ttttttctcc tgattttagt tggcggcggc
    33361 ctacttaccc taccattttt tagtaatagt gggcatggga caaattttat cgatgcgctt
    33421 ttcactgcaa cttctgctgt ctgtgtaacg ggattgacaa cattgaatac agcagagcat
    33481 tggaacagtg ctggtcaatt tttgatcatg cttttgattg agatcggcgg tcttggtttt
    33541 atgatggttc cgattctatg ctttgcattg ataaagaaga aagtcagtct cagcacacgt
    33601 attatattaa aagaagcgct gaatctagaa gaagtatcag gtgtgatgaa gctcatgctt
    33661 tacatcctaa aattggcctt tgtgatccaa ttgattggta cggttgcttt atcttttgta
    33721 tttgtgcctg aatttggctg gttgaaaggt atctggtaca gtttgttcca tgcaatctct
    33781 agtttttgta atgcagggtt tgatttgtta ggagacagtt tagccaatca ccagcaaaat
    33841 gtttatttga tcatggtggt atctgctttg atcatttctg gtgggttagg cttcatcgta
    33901 tggcgtgatt tactggaata tcatcagaaa aagaagatga cgattcattc aaaaatcgca
    33961 ttaaccgtta caggtaccct tttattaggc ggattcgttg tgttcttttt cacagagcgc
    34021 aatggggcaa cgctagtgga agggaatatg tttcaacgat tggcaaacac cttttttatg
    34081 agtgtgacac ctagaacggc tggatattat tcagttgatt acctccatat gagccatgca
    34141 ggtctgattt taacgatgtt tttgatgtac atcggcggaa catctgggtc gacggccggc
    34201 ggattgaaaa caactacgtt aggtgtgttg ctgatccaga tgcgttcgat gttgaaagga
    34261 cgtacgagag cggaagcatt tggccgtacc atccgacaag gcgcagtgtt gcgggcactt
    34321 actttatttt ttgttacgtt gacgttgtgt gtagtcgcca tcatgatttt atcggtgact
    34381 gaaacgatac ctaaaacttc tggcatcgaa tatattgctt ttgaggtctt ctctgcgttt
    34441 ggtacagtag gtcttacgat gggattgacg ccagacttga ctgcaatagg gaaattgatc
    34501 attatagcgc ttatgtacat tggacgagtt ggtgtattga ctgtggtctt ctctctgatg
    34561 acaaaagcac aaagaacaca atcaaaatac aaatatccag aagaaagtgt catgattgga
    34621 taatttcatc ttctgacaga aacctagtga tttagtaaaa taagaaaata aaataatttt
    34681 tcttgcttct tggatacttt aagtgcaaaa tgttcgttta ttttttgagg cactacccgt
    34741 tgttgaacct cgggtagtgc ctctttttta ttgaaaggaa tcaataagat ttgattcctt
    34801 tatttatcaa taggttataa ttcatatttt tttatttttt cttttacgat acttagtcca
    34861 gaagctaaaa tttcaaggtt attagaggat agggaaattc gaacgaatgc atctggttgc
    34921 gcacgtgtag taaagcgtct ggaatgataa agtcggatac cgttagcaag aaagtcattc
    34981 tcaattatct tagggtcaat ctcaggatca actggaagaa ttcgatagta agggacacga
    35041 ttcgttggtt tttctacttt gaaaagagaa tcaaaaagct gattggctct ttttgtaaga
    35101 cttaatttag tttctaagat cctatttgct tcatttgaat ggaggatttg agtgatgact
    35161 tccacatcta atccagaagt tttcacattt atattaaaaa ttgcttgttc tatcttgctt
    35221 tggacatgta ctggaactac aagataagca actcgcaatc cagaacaaat aaattttgtc
    35281 attccagcta agtagattgt ttggttaggt aataaatttt ggaaaggagg aatgatcgta
    35341 tgttgatagt aagttgttaa aaatgaatgg atatcatctt caataaccca tagaccttct
    35401 ttttcaatca cttcggctaa ttgctctcgt cttttgtgag agatttgaaa ccctatagga
    35461 ttattacaag aaggcataag aaagacacca tgaatcttct tttttctaca ttcctgaatc
    35521 aatatatcag gtcgcattcc ttgctcgtca aaatcaattg gaacgatctc taaatgatat
    35581 aactgagcca attcaatgaa attagcgtat gtatatcggt ctgttgctat tctatcacct
    35641 ggagagaaaa gtgcagaaag tgtgatagcc aatccatttt gaacaccgga aacaatagat
    35701 agagattcta aggacggaat gactccttga gtttttaacc aatttgctgc agtagtcaat
    35761 tgaaaatttg tgcctttggg atcttggtaa ttaagcaaac caacaagatt tgggttatta
    35821 ctagttgatt gaataaacgg gacaacgaat ttattacatt cttcaaaaga actaaccaga
    35881 ccaaaatcaa tgatatgttc ggttacttca ttggtagaga tggtgatgga ctcaaagaca
    35941 ttgggagaaa taaatgtgcc acttccaata ttcgtataca gcaaaccttt ctcaattcca
    36001 tatttataag ccttgccaac ggtagtaaaa tttaaatcta aataatcagc tagctctctt
    36061 tgggagggta actgagtgtt tttctgtaat ttattcttta aaatatcttg ttctaattgt
    36121 tgaatcaacg atcgataata aggacgcttc aatttttgtt tgtctggtcg ccaagttaac
    36181 gggtaattgt cataagaatt aataggcatt ttctccactc cttaaaattg tataccatac
    36241 aattttacca ttgattgtat tgattttaga agttaatctt ttgtgaggag ggaattgtct
    36301 atgaaaatta ttaattttga ggaagtagta gcttctttta gttttgaaga agcgattcaa
    36361 gtaatgaaaa aatgtttttt tgattatgaa agtggtaaaa tcagccaaaa tcctcgattg
    36421 gtggaaattt tacctgacgg aaaaggcaaa aatatgtttg cgatgatgcc tgcttatttg
    36481 ggggagaaca gatattttgg cacaaaagtc attaccgctt ttccggataa tcatcagtat
    36541 catttacctt ctcatttagg agagattttc ttgtttgatg ctcaaaacgg actacccaaa
    36601 gcattgataa acgcaaatgc agtcacctgg attcgaacag ctgctgtatc tgcgctggca
    36661 acagattact tagcaaatcc gcatgcagaa acacttgctt taattggagc tggtcaacaa
    36721 gcattgtcgc atttgactgc gatttctacc attcgtccca tcactacagt gtttgtttac
    36781 gatattttag aagaaagacg aaatactttt atcgctaaag ctaaaaaaca gtatcctaaa
    36841 ataacgttta taaatgcaat atcagtagaa gatgcagtac gtccagcgga aatcatttgt
    36901 acgttgacct ctagtaaaga ggcatttctt caaaaagagt gggtaaggga agacgcacat
    36961 atcaatgctg tgggcacatt tactcctgat acaagagaga taagtacatc gttgatggaa
    37021 acttctcaaa tctatgtaga tgattactca gctgccttaa cagaaagcgg ggacctgctt
    37081 atagccatgg cagaaggaga tttagaggaa tcttgtattg ttggtacatt aggcgaatta
    37141 gtttctgaga aaaaaacatt ttataaagga gaatcgaggc cgacgatttt cgacgcagtt
    37201 ggtctagcta ttgaagatct ttgttgtgca gaatatattt ataacaaatt agagaaaggg
    37261 gctttaaaat gaacttagat tattacgtag ttgatgcatt tgcagatgag gtgttcaaag
    37321 gaaatccagc agcggtttat gtgctagaag aatggctgcc agaaggtacg atgcaaaaaa
    37381 ttgccattga aaacaattta tctgaaacag catttacagt gaagaaaaac caagaatttg
    37441 agcttagatg gtttacgcca gatcgagaaa tcgatctttg tggtcacgcg acattagcaa
    37501 cagcatttgt tttatttaac tattacaaaa tacctgatga aacgattaaa ttttctactc
    37561 aaagcggtaa tctatttgtg acaagaatta aagattatta ttacatggat tttcctagta
    37621 ttatgccgaa aaaagtgccg atattgtctg aatatgaaga agcgattggg gctaagatta
    37681 aagaagccta cttagcacgt gatttatttt tcgtattaga agatgaaaaa acggtggcta
    37741 aattgcagcc agattttaca gctatcaaaa attttgaatt aggaatagga gtcatcgtga
    37801 cagcagaaag tgtgcaaaaa gactttgttt ctagaacctt ctttccaaaa ttaacaatca
    37861 atgaagatcc agtatgtgga tcagcacatt ctaatcttat tccttattgg gcagaaagaa
    37921 tgaataaaac aaaattgtca gcttatcaaa tgtcatcaag gggcggggat ctagaatgtg
    37981 aattaaaaga agatcgtgtg ataataggag gaaaagcagt tttgttttct aaaggtacct
    38041 cgtttatttg atttctttca aatgaattaa aaataaattg gtggagagtg gcaaccttat
    38101 agctacaatg gttgttaaaa aaagacgcaa actttttcaa tttaatgaaa agtttgcgtc
    38161 tcattttaat tattggtgtt tgttttttat tcaatcaaga gtaaaatgcc ccatactaac
    38221 tatcctcgga tgacttcgat tttataacca tcagggtcaa tgacaaagta gtaagaaggc
    38281 gcagtgccag gtaatccttt taagtcagta atctcaagac cagcagcttt atgttgctcg
    38341 tgtaattttt ctagatcatc agctgctata gcgatatgac catagccgtc tcctagatca
    38401 tacgcaccat gatcatagtt gtaagtcaac tctaattcat agtcatcccc aggaagtgtc
    38461 aaataaacaa gtgtaaattt gttttctgga aaatcacggc ggcggctttc ttcaaaacca
    38521 aatgcctttt gataaaattc gattgatgct tcaagatctt tcactcgaac acatgtgtga
    38581 gccattttca tagattcatc tctccttttc cttttactca atcataacaa aaagaagtaa
    38641 ggaaatagtt gatttgtgct tgttcatgag aaatttctca tgtaaaatgg atagaaaata
    38701 aaactgttaa ggtggaaact attcatggat aaaccaattt ttggtgaaaa aaagcaattt
    38761 gctgattatc aaacccgtta tgcagcatat attgtcatag aaagagatca gcagattgca
    38821 gtaatcgagg ctccaaatgg tgcttttttt cttcctggcg gggaaattga aggagaagag
    38881 acgaaagaag aagcgattgt ccgtgagctg atagaagaaa tgggaattgt ggcagaaatt
    38941 tcttcttatc tgggagaagc tgatgagtat ttttactcga attatcgtgc aacttattat
    39001 tataatccag gatatttctt tgttgctgat tcttggaagc gtataggaga accaactgaa
    39061 aagaccaata aaatttggtg ggtgagccct caagaagcgc ttgtgaaatt gaaacgtggt
    39121 agccaccgat gggcagtcga gagatggatc gaaaaaaata aaaactgaaa gaaagcgagt
    39181 agatcagctt tctctcagtt tttttattta ttacagtaca tattttttga ttgcttcagc
    39241 tacaccgtgc tcgtcgtttg atgaagtgat gacatttgct gcttctttga caagagaaac
    39301 ggcatttccc attgctactc ctagaccagc atattcaatc atggataagt cgttctcgtt
    39361 atctccgata gccatgattt catcttgatc aataccaagg tgctgtgcga gattcgcaac
    39421 tgccgcacct ttacttgctt ctttatttag tacttcgaag taatagggcg cacttttgac
    39481 cgttgtgtat ttatcacgga aagtttgcgg taaacgcgca attgctgcat ctaaaatttc
    39541 tggttcgtcg atcatcatca ttttgacgat gttcatgtct ggtgtcattt cttcaggtgt
    39601 tcgatatttt agcggcatct tgactaaact tgcttcgtgg atcgtataag cgctgatatc
    39661 tcgattaggc gtgtagatcg ctttgtcatc gatcgaatgg agatgactgc cgacacggcg
    39721 tgccattact tcgatctcta ggaaatcttc atgtgtcagt ccgtgacggg cgatgatttt
    39781 acctgatttc gtttgttgta cgagtgcccc gttataagta ataacgtaat cattatcttg
    39841 aaaaaggttc aactcgttta actgttcctg gacacctggt aagggacggc cagtgcataa
    39901 aacgatcgaa acaccttttg caacagcagc ggcaatcgct tcttttactt cttttgttac
    39961 ttctcttttc tcatttaata aagtaccatc gatgtcgata gcgactagtt tgatagacat
    40021 aatttcctcc aatatatttt aatttatttc aatcaatgcg ccattacgga tatggctggc
    40081 aaattcttga taagtttcgt caaataaatc ataatgatca cgcaaggacg gatcaaccat
    40141 ttcttttgga aagaaaaatc gctcatctcc ttgttcttgt cccgctaatg cagcaacaag
    40201 ctgactaacc tgtgataatt ctatcaaagt tccgtcattt cgcaaaatct cgatttgtgt
    40261 gcgatgtctg ccttgttctg ggcgataaaa atcataaggt agatcgtagc tagaattcac
    40321 agcagtgtaa taaacaggat tatatccgac cttttctact aacaaagtga gttcttggac
    40381 taattttgaa tcccggttgc cagaaaaagt agcagatttc agtggtttac gattcaaaaa
    40441 acgtttagct aaatcattta aaataggatc agcagattca gaccattgag taaagtaagt
    40501 gcccaagacc ccatcatcaa gtttgaggta ttcttctaaa gtaaagcttc cgtcaagaaa
    40561 tggcagaagt aattgagaat ggagttcaaa actgctggca tcttcttgat acaactcgtg
    40621 tgcgcgatga agcagatgct ccaaaattac ttccatacca cgggaaacag gatggaagta
    40681 cacttgcaca tacatttgat atcggctaac gatataatct tccactgcat gcatgccact
    40741 catggaaaaa gcgatcccgc cttcataagg acgaatcaca cgtaatattc gggtaagatc
    40801 aaatgttcca tattctgttc cagtgaaata agcatcccga agcaaatagt ccattcgatc
    40861 tgcatcgatc tgactagaaa tcatttggac aacttgtggg ttggggtaag ttttttggat
    40921 cacactagct accttttcag gaaaaccttc ttctactcgg ttaagaatct gatacacttc
    40981 tgtttctgga gaagtgatga tctctacagt gatggcttca tgattcgtat ggaagatatg
    41041 ttcaaatgta tgagagtaag gaccatgacc gacatcatgc aacagtgccg cacataaagt
    41101 caccagccgt tcctgatcat cccagcctcc gttgcctatt ttttcttttg aaaaatttcg
    41161 agaaaagata tcgcagattc gtcttgaaat ctcataaacg cctaatgaat gagtaaaacg
    41221 gctatgttct gctccgtgaa aagtgaaaga agaagtgcct aattgtttaa tgcgtcgtag
    41281 acgttggact tctttcgaat tgatcaaatc taagattact tgatgctgga catggatata
    41341 gttatggact ggatcacgaa aaactttttc cataggcagc atttgatatt tataaggggt
    41401 tgtcataatg tagctccttt atgttattac gttgttccat tctctggatt tggttgttcc
    41461 attgctccag ctggatttct ttttttagcc agtcggtaga atcctgtaaa tcacttgcag
    41521 aatacagctt ttcaaaagct tttgcaaatg cttctttgac ttcttttaca aaaaggggtt
    41581 ggtcaagcag ttcttcaagt gttgccattg tagcaggatc cactgcagga tagccatttg
    41641 taccaaagtc ttcttttaaa gcagattgat aaaatcgctt catgacttgc ccacgttttt
    41701 cctgattacc gttgacactt aagtacatca taacagaaat cccatttttg atccgacgct
    41761 gagcgatacc ggcaaatttt ttgccatgga tgcttaaatc ataagttcca ggacaataag
    41821 aatgggtgat ttcgaatgct tgtatcggtg cctttggaaa agcgtattta gtcaatagga
    41881 gcatttgctc gtaagcgtca tctatggtta ttttttttgt gtcactttgg gggaaaatca
    41941 aagaaatatt caaaattcct tcatctgata cgatccctaa tccacctgaa tttctgatca
    42001 ctggagcgta acctgcatct tccagtgttt ggatcccgtc acttagaaaa ggagttcgaa
    42061 catccttcat acctaagatg actgtgcagt catattgcca gaaatgtaaa aagatttgct
    42121 ggtgttcttt agaatattcc gttaatatat ctgttaatgc aaaaggggaa aagtcgtttt
    42181 tttgataaat gtgctgatct agtcgaatcg cagggttcat tcaaccggct cctttgtata
    42241 aattcatatt ttctacaata ttatactcta aaatcaaaga gttgttttgg aaaaaaggtt
    42301 ttctgtaaaa atggacaagt tggttgacaa aacaaaagaa actaggaaca atgtagctat
    42361 gagaagtaaa ggagaatgaa taatggaatt atcacaagga acaccgattt caatcaaatt
    42421 gcgtacaaaa gtaaaacagc aaggggaagt gcaagatttt tattttgatt tgaaagggca
    42481 aatggtgaca attggcgata cgctgtacat acgttataaa gagattcagg aggagacggg
    42541 cgatgagatt cctgtaacga tcaaattagt tccagatggt catgtacagc tgatccgtgc
    42601 aggagaaatg cggatgcgtt tgaaatttgg ctataaagaa cggttagaaa catcctatcg
    42661 aacaccatac ggtatgatcc agattgctac ttttacgaaa gaactgcatg ttagtttgaa
    42721 agaccgtccc acagcaggga aggttcgaat cgattatgat ctgttcatgg gaccggaaaa
    42781 aatcggcgaa tattatttga ccttggattt tacagcgtaa atataaaaga aaagtttgat
    42841 tttttgtgtc tgattttgta tgataaggag tagactgtga aaggacgtgt cctgattgga
    42901 aattagtgta tttgaaggtg caaacaaaag cgaattatca atgatcgaag tagcacacgc
    42961 gatcttagaa caacgtggcg atgtcatgga tttttctgat ttagctaacc agatccaaaa
    43021 ctatcttggg aaatcagaca gtgaaattcg tgattcactc gcacaatttt atactgactt
    43081 gaatattgac ggcagcttta tctcattagg ggataatcgt tggggcttgc gttcatggta
    43141 tgctatcgat tcgatcgatg aagaagtaaa ccatggaatg gacgaagagg atgaagatac
    43201 tccacgtcgc cgtaaacgca agaaagtcaa cgcctttatc aatgatgatg aagacgcgat
    43261 cgattacaat gacgatgacc cagaagatac agatctgaca gaagaagatg acgatgatct
    43321 gtttgatgac gatgatgatg aagatgaaga aatcgctgct tataattctg acttgcaaga
    43381 aatcggagca gatgacccga cagatgatga agaagacttg ccaggaaata tcgaagaaga
    43441 tttaagtatc atagacgaag acgatgatga tgaagattat gaagaggaag aattttctga
    43501 ctctgaaaaa gaataaacat tattttctta cgagaggttg tgacagagac gatcagccta
    43561 tcagaataag gaggtgtgac acgatttttg tcacaccttc ttttttgtat ataaaaatcc
    43621 caagtaaata cataaaaaat aaaaaaattg aaacttttag cgcaccttgt acgtcatatt
    43681 aagtgaggca gaaaggagtg gagaatgatt tttactggat ataagaaaaa acggcagatc
    43741 gaaaaatacc gtcacctgct gaatggactc atcgaaactg attatcaaaa aatgttccgt
    43801 atcacgatga attacgtaca tgataaagaa gaggccttag atgtgatgca agatagtttt
    43861 cataaagccc tgaactattt tgaaaaagaa aaagagatcg agcattttag tgcatggttt
    43921 tatcggatat tgatccgcac ggcattagat agttggcgca gacaaaaaag gacgcctgtg
    43981 gacttatttg aaattcaaga tatcccccaa cagttacctt tagaaacttc cgttgcagag
    44041 ctccatatga ttttagataa aatagacagt ccggaaaaag agattctgat cctctacttt
    44101 tttgaaggat ttcgtttgaa agaaattgcg actatcttgg atatgaatga aaacacagtt
    44161 aaaacgaaaa tgtaccgctc attgaatgct ttacgtcaaa tcctagaatg aaggagagaa
    44221 gagtgccatg tattcccaaa aagaaaattt aaaaaaacta aagaaaactt ataaagaaca
    44281 agcaattccc aaagggctta aagaggagat ccgccagcgt tttattatcg aagagcaatc
    44341 atttataaaa gcaaagcgga gaaagagacg tctccaaggg ttcggagtat ctttggctat
    44401 cgtaatgatt acaacaagta gccttctttt taatagtcaa gttcgaagct ttgcagaaga
    44461 tttacccatc ttaggatcag tcattgaatt gatcttaggc gaacgcttta ctgatcgatc
    44521 tgaaaaaatc gatattcagg taccgaagat caatacacaa aatgagaaag aaaataaaac
    44581 aattcatgga ttaaatcaaa aatactttcg cgaaggacaa gcagattttg aaaaagctga
    44641 aaaagaatat ggaaattttg aaacggatca ttaccaagtt ttgggagatt atcagaaaat
    44701 cgtagacgat aaccggtttc tcgtgattga aaggcagatc acccaaacag cagcagatag
    44761 ccatgttgaa aaaagatacg acacaatcga caagaaaaac agtgtccagc tctcacttcc
    44821 acttttattc aaagatgaca cctatctatc tgttttgaca aaagaagtca aacggcagat
    44881 ggccgaacaa gtcaaggaag atccatctaa gtactattgg actgagcaag atattcaaga
    44941 agggacgata gaaaaaccaa cacttgttac gcctacacga agtttttatt tgaacaaaga
    45001 gcatcaatta gttttgactt tttctcaata cgaaattgct cctggttata tgggtacacc
    45061 agaatttgtc attcctaagt ccgtgacaaa aacgattttg gcatcggaag attatttgga
    45121 tcattagacg agaagtagtt gcgactagca gtttcaattt tcaagtaagt acaagtaaat
    45181 aataagaaga gaaaaagaga aagaagagat atagtgaaaa gaaattattt agttatcagt
    45241 attattgctt tatccgtgct tttgtttttc gaaattactt cggtggcctc cttgatcacc
    45301 gaagtaaaag gacaaacaca ctcttcggag cattcgtcac aatctttcaa acaatcagaa
    45361 caatcaacca ttaaaagcca atcaactgaa acagctaacg tcaaagaagc cattcaagaa
    45421 tcagcggaaa aggtacaaag tcagtcatca caatcaacac aagacagtac aaaaacgagc
    45481 cgagatccgg ctgtcaaaag cgtcgcaatc agctttgatg atggaccagg agcgaccaca
    45541 acaccgcagc ttctgcgaat cttaaaagaa aaaaacgtgc atgccacttt tttcgtctta
    45601 ggagaaaata cggcgcagca tcctgaaatc gtgaagcaga cagctgaagc agggcacgag
    45661 attggcaatc acacatacga tcatcagaat ctggccactc tttctgccca gtcgatgacg
    45721 gaggaagtga cgaaagcaga cactgagatc aaaaaagtca ctggcaaaac ccccactttt
    45781 gttcgtccgc cctatggttc tgtcacgaat gtaggagcaa cgatcatcca gcgaccgatc
    45841 atcgaatggt ctgttgattc agaagattgg aagacaagaa atcctgattt gattttgcag
    45901 aagatccaag caacagtata cgatggggca attattttat tccatgatat ctatcctgaa
    45961 acgattcgtg ccgttcctca agtgatcgat tatctgaaag agtaagggta tcgcatcacg
    46021 acagttgggg atttattagg gcatccaacg gctgtcgaga actattatgg cagaaacgat
    46081 catcggccag ttcagtaagt gagacaagta tctttaataa ataacacatt ttaataagta
    46141 gttgaacaca taactacctt acttgcaaag gcttaacaat atctatacag gtacaacaaa
    46201 aaactgtcca ccaattttct ttggcggaca gttttcactt aaaaataaag aagcaactat
    46261 tcgtaaatta tgctaaaata gcagtagaac gcgtcctgag ggaatcgaac ccccgtctca
    46321 agaaccggaa tcttacgtga tatccactac actaaggacg caagcactgg gataattgta
    46381 actaaacaga taaaaaatta caaggggatt ggacaaaaaa atgaaatttg agcaaaattt
    46441 ttcacaaaaa cagcagcaga cacagaaact agccatgacg caacagttgc aacagtccat
    46501 ccaagtttta caatataaca gtgaggagct gttggcattc gttgagaatc aagcaatgga
    46561 aaatccattg gtggaagttg ttgagccgga atggcagcca gattacataa aagcttcttc
    46621 atcttcttat gaaggagaag agacaaatta cctaaatcag attcctgata caaaagggtc
    46681 tttatttgat tcattgatcg aacaagtcca tttgaattac cgagatactt ttttgaggaa
    46741 aatcgttctt tatcttgtag aatacatcga tttgaacgga tttttgacga ttagtttaga
    46801 agaagccgga aaagagattg gagctacgcc tatccaaatg ctcgatgcgt tgactctgat
    46861 tcagcaatta gaaccagctg gagtaggtgc acgtagtttg caagaatgtc tcatgcttca
    46921 aacagaacga gatgattatg cgccggaatt agcttatatc gtgttggaag aatgttttga
    46981 ggaactggtg gagcgaaaat ggaaagaaat cgcacaacgt ttttctgttg atctacatgc
    47041 tgttcagcag atattcgact atttacaaac gttgagtcca agccctggcc ggattttcga
    47101 ccgtagcagc gaattgtaca ttattcctga tgtccgggta ttagtggacg acgataaaaa
    47161 tgtacaagtt atctcaaacc gaaaaaatca gccaaatata cgctttcaag agagttactt
    47221 caaacaaatg tcacaacaag cagataaaga aactgaaaat tatttaaaag aacggaaaca
    47281 ggaattcgaa tggttgaaga aaacgatcct acaacgtggg gatacaattt tgcgggttgc
    47341 tcaagtcatt gtttcccggc aaaaagcttt ctttatcgac aaggaacgtc caatcaagcc
    47401 tcttacgtta aaggaagttg caactgagat agatgtgcat gaatccacgg tcagtcgtgc
    47461 agtcaacggg aaatatttgg aaacagactt cggtgtattt gaattaaaaa aatttttcac
    47521 tacacgaatt cctacgaata gtacagaaca gacagaagac ctttcagcag atacagcgaa
    47581 gaaaaagctg caggaattag tcgatcaaga agacaaaaac aagccgttgt ctgaccagaa
    47641 attggttgaa ttgctgaaaa aagatgagat agcgatctca agacgaacag tagcaaaata
    47701 tcgtgattta ttaggaatcc cgagttcatc aaaaagaaaa cgttatgata actaatcagt
    47761 caaaagacta gaaaaagtat ttcacttttt ctagtctttt tagttgaaaa acgagagcaa
    47821 aactgttaga cttacagtcg tgaggttgag atttcccttt attgatgtga aattcgaata
    47881 gttaatttct ttttttatcg tatatgggtc gttttaagtc tacattggac gtaaagtgtc
    47941 caactaagga gatcgctatg ctggatgaaa taaaaatgat tgaatctgtt gcaccagata
    48001 ttatcgaagt gttgcaagaa cgctataaaa ttttacgaaa tatctattgg atgcagccga
    48061 ttggacgtcg aagtttatcg gaaagtatgg ggatcacaga acgagtattg cgaacagaaa
    48121 cagatctttt gaaaaatctg aatttgatcg acacctcaaa aagcggtatg acgctgacaa
    48181 ctaagggcga agaagtttat caaagccttg aaaacttcat ggatcagctt ttaggtacgc
    48241 atcaaaccga acaacagttg gcagaatatt ttggtaacca acgctgtatc gttgtttcag
    48301 gaaacagcga agagcagacc aaagtggctg atgcattcgg cgaagcgctg agcgaagccc
    48361 tagaccgact acttccagaa ggcgagaata tcatcgctgt gatgggagga actactatgg
    48421 ctgtggtagc cgaacaattg tctaatctgg aaaataagaa acggcataac ctgtttgtcc
    48481 ctgcaagagg cgggattggt gaagcgataa ctgtacaggc aaattctgtc agtgcaagaa
    48541 tggctgctaa agcaaacggt aaccaccgtg cactttatgt tccggaacaa ttaagtctgg
    48601 caacttacaa ttctttactc aatgagccat ctatccaaga agtcttaaac ttgattagtg
    48661 aagcgaattg tgttattcat agtattgggc gtgcattaca catggcagca cgtcgtaaga
    48721 tgactgaaaa agaattagtc atgctgaaac aagcaaatgc tgttgcggaa tcttttggct
    48781 actttttcaa tgaaaaaggt gaagtcgttt ataaggtccc tagaatcggc atagaattgc
    48841 aagatttgga aaaagtcccg atcatcatgg caatcgcggg cggaaaatca aaagctaaag
    48901 caattcgagc ttatatgaaa aatgcaccaa aacaaacgtg gctcatcact gatgaagctg
    48961 ctgcaaatga gattttaaaa ggggtaaccc tttaaaataa atattttttt gattttcata
    49021 aggaggaaat cttaaatgac agttaaagta ggtattaatg gttttggacg tattggacgt
    49081 ctagcattcc gtcgtatcca agatgtagat ggaatcgaag tagtagcaat caacgacttg
    49141 acagatgcta aaatgttggc acacttgtta aaatacgaca caactcaagg acgtttcaac
    49201 ggaacagttg aagttcatga aggttcattc aacgtaaacg gaaaagaagt taaagtatta
    49261 gctaaccgca acccagaaga attaccatgg ggcgaactag gcgtagatat cgttctagaa
    49321 tgtactggtt tcttcacttc taaatcagca gctgaaaaac atttaacagc tggtgctaaa
    49381 cgcgttgtta tctctgctcc tggcggaaac gatgttccaa caatcgttta taacacaaac
    49441 cacgaaacat taactggtaa agaaacagtt atctcaggtg cttcatgtac tactaactgt
    49501 ttagctccta tggctaaaac attgaacgac aaatttggtg ttgttgaagg attaatgaca
    49561 actatccacg cttacacagg tgaccaaatg actctagacg gacctcatcc taaaggtgac
    49621 ttccgccgtg cacgcgctgc tgctgcaaac atcgttccta actcaacagg tgctgctaaa
    49681 gctatcggtt tagtaattcc tgaattgaac ggtaaattag acggagctgc tcaacgtgtt
    49741 cctgtaccaa caggttcatt aacagaatta gtaacagttc ttgaaaaaga agtaactgtt
    49801 gacgaaatca atgcagcaat gaaagaagct tcaaacgaat cttacggata caacacagac
    49861 gaaatcgttt cttcagatat cgttggtatg acttacggtt cattatttga tgctacacaa
    49921 actaaagtaa tgacagttgg cgacaaacaa ttagttaaaa ctgttgcttg gtacgacaac
    49981 gaaatgtcat acactgcaca attagtacgt actttagaat acttcgctaa cttataagat
    50041 agacaaacgt acaagtgtaa attatagaca tgtacattta aaagcgggga agcaatcgcg
    50101 cttcttccgc tttttttgat aataagttta ttcaggagga aataaaatgg ctaagaaaac
    50161 agtgaaagat atcgatttaa aagacaaaaa agttcttgtc cgtgttgact tcaacgttcc
    50221 tttgaaagac ggcgtgatca ctgacgacac tcgtatcaaa gcagcattgc caacaatcaa
    50281 ctacgttcta gaacaaggcg gaaaagcaat ccttttctct caccttggac gtgtaaaaac
    50341 agaagaagat aaagaaggaa aatctttagc tccagttgca aaacgtctag gcgaattatt
    50401 aggtaaagaa gtaacattcg tacctgaaac tcgcggagaa caattagaag aagcaatccg
    50461 caacatgaat gacggcgacg ttgtcgtatt cgaaaataca cgatttgaag atattgacgg
    50521 taaaaaagaa agcaaaaatg atacagaact aggtaaatac tgggcttcat taggcgatgt
    50581 atttgttaac gatgctttcg gtacagctca ccgtgcacat gcttctaacg taggtatcgc
    50641 ttcaactggt atcccaacag ttgctggatt cttgatggaa aaagaaatca agttcatcgg
    50701 tgaagcagta gaagaaccaa aacgaccaat gattgcaatc cttggtggcg caaaagtttc
    50761 tgataaaatc ggcgtaatcg aaaacttgat tcctaaagca gataaaatct tgatcggtgg
    50821 cggaatgact tacacattct acgaagcaaa aggaatcaag atcggtaact ctctagtaga
    50881 agctgataaa gtggaactag caaaagaatt aatcgaaaaa gcaggcgaca aacttgtctt
    50941 gccaatcgac aatgtctgtg caccagaatt ttcaaatgat gttgaaacac aagtaatcga
    51001 aggagacatt cctgatggtt tgatggcttt agacatcggc ccagcatcag taaaattatt
    51061 tgctgataca ttacaaggtg caaaaacagt tgtttggaac ggacctatgg gtgtatttga
    51121 aatgagtaac tttgctaaag gtacaatcgg tgtttgtgaa gcaatcgcta acttagaagg
    51181 cgcaacaaca atcatcggtg gcggagactc agctgcagca gcagaacaat taggatttgc
    51241 tgacaaattc acacacatct caacaggtgg tggcgcaagc ttggaattgc ttgaaggtaa
    51301 agaattacca ggactagcag caatcaacga taaataaacg accaagtttg ctcaattctg
    51361 acgagtaatc gatcaaaagg tgaagggagt tttcatgact ccctagccat ttttcaataa
    51421 attaaggagt gtgttcctca atgcgtaaac ctattatcgc aggtaactgg aaaatgaaca
    51481 aaactgcatc agaagcaaaa gaatttgctg aagcagtaaa aaacaaaatc ccttcaaatg
    51541 acaaagttga ttcagtcatc ggatctcctg cattattctt acaagaatta atgacatcag
    51601 ctgaaggtac agaactaaaa atctcagcac aaaactgcta ctgggaaaac tcaggtgcgt
    51661 tcactggtga aacttcacca gcagctcttg ctgatctagg tgttcattat gtgatcatcg
    51721 gacattcaga acgtcgtgaa tatttccatg aaacagacga agacatcaat aaaaaagcaa
    51781 aagctatctt tgcaaatggt atgacaccaa tcctatgctg cggcgaatct ttagaaacct
    51841 atgaagcagg caaaactgct gaatggatcg aaggacaaat tacagctggt ttagctgatc
    51901 tttcagctga acaagtgtca aacatggtta ttgcttatga accaatctgg gcaatcggta
    51961 ctggtaaatc agctgacgca caaatcgctg acgaaatttg tggagttgta cgtcaaacag
    52021 ttgaaaaact ttatggaaaa gaagtatcag aagcagttcg tatccaatac ggcggttctg
    52081 taaaaccaga aaatattgct gaatacatgg caaaagaaaa tgttgacggt gctttagtcg
    52141 gtggcgcaag cttgcaagca gattcatttt tgtcattgtt agacgctgta aaataattgt
    52201 tgaaaatttg cgaaaaatgc aagaaatgtt tgcactaatg agcaaaatta actaaaatcg
    52261 tatatgaggg aaatccctta ggaaaaaaca aactcaaagg agagacaaaa catgtcaatt
    52321 attactgatg tttacgctcg cgagatctta gactcacgtg gtaacccaac aatcgaagta
    52381 gaagtataca cagaaagcgg agcttttggc cgcggaatgg ttccttcagg tgcttcaact
    52441 ggtgaatacg aagcagttga attacgtgac ggagacaaag ctcgttatgg cggtaaaggt
    52501 gtaactaaag ctgtcgacaa cgtaaacaac atcattgctg aagcaatcat tggctacgat
    52561 gttcgtgacc aaatggctat cgacaaagct atgatcgctt tagacggaac tcctaacaaa
    52621 ggtaaattag gtgcgaacgc tattttaggt gtttctatcg ctgttgcacg tgcagctgct
    52681 gactacctag aagtaccttt ataccactac ctaggcggat tcaacacaaa agtattgcca
    52741 acaccaatga tgaacatcat caacggcgga tcacatgctg ataactcaat cgacttccaa
    52801 gaattcatga tcatgcctgt tggcgctcca acattcaaag aagctctacg tatgggtgct
    52861 gaagtattcc acgcattagc ttcaatcttg aaagctcgcg gattagcaac ttctgttggt
    52921 gacgaaggtg gatttgctcc aaaccttggt tcaaacgaag aaggttttga agtaatcatc
    52981 gaagcaatcg aaaaagctgg ctatgtacct ggtaaagacg ttgttcttgc tatggatgct
    53041 gcttcttcag aattctacga caaagaaaaa ggtgtttacg tactagctga ctcaggcgaa
    53101 ggcgaaaaaa caactgacga aatgatcaaa ttctacgaag aattagtttc taaatatcca
    53161 atcatctcaa tcgaagatgg attagacgaa aacgactggg acggattcaa gaaattaact
    53221 gacgtattag gcgacaaagt tcaattagtt ggtgacgact tgttcgtaac aaacactcaa
    53281 aaattatctg aaggtatcga aaaaggaatt gctaactcaa tccttatcaa agtgaaccaa
    53341 atcggtacat taacagaaac tttcgaagct atcgaaatgg ctaaagaagc tggctacaca
    53401 gcagttgtat ctcaccgttc tggtgaaaca gaagattcaa caatctctga tatcgctgtt
    53461 gcaacaaatg ctggccaaat caaaactggt tctctatcac gtactgaccg tattgctaaa
    53521 tacaaccaat tactacgtat cgaagaccaa cttggtgaag ttgcagaata caaaggtttg
    53581 aaatctttct acaacttaaa aaacaaataa ttcttttcta atgaagatac atgatcgact
    53641 attgaaagat agtcgagtat gatcacttag ttaagtaatc gaactctcta cttgctgaaa
    53701 tatcagcagg tagagagttt
//
LOCUS       DAPBAF010000017        52484 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.017, whole genome shotgun sequence.
ACCESSION   DAPBAF010000017 DAPBAF010000000
VERSION     DAPBAF010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 52484)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52484)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52484
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.017"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            256..531
                     /locus_tag="RD451_001142"
     CDS             256..531
                     /locus_tag="RD451_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566415.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            544..2622
                     /locus_tag="RD451_001143"
     CDS             544..2622
                     /locus_tag="RD451_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HDT7566416.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            2782..4668
                     /locus_tag="RD451_001144"
     CDS             2782..4668
                     /locus_tag="RD451_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HDT7566417.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            4680..5627
                     /locus_tag="RD451_001145"
     CDS             4680..5627
                     /locus_tag="RD451_001145"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HDT7566418.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            5647..6174
                     /locus_tag="RD451_001146"
     CDS             5647..6174
                     /locus_tag="RD451_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HDT7566419.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(6237..6890)
                     /locus_tag="RD451_001147"
     CDS             complement(6237..6890)
                     /locus_tag="RD451_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HDT7566420.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            7022..7864
                     /locus_tag="RD451_001148"
     CDS             7022..7864
                     /locus_tag="RD451_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HDT7566421.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            8022..8918
                     /locus_tag="RD451_001149"
     CDS             8022..8918
                     /locus_tag="RD451_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HDT7566422.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            8921..9634
                     /locus_tag="RD451_001150"
     CDS             8921..9634
                     /locus_tag="RD451_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HDT7566423.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            9654..10172
                     /gene="msrA"
                     /locus_tag="RD451_001151"
     CDS             9654..10172
                     /gene="msrA"
                     /locus_tag="RD451_001151"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HDT7566424.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQDYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            10169..10396
                     /locus_tag="RD451_001152"
     CDS             10169..10396
                     /locus_tag="RD451_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HDT7566425.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            10548..11099
                     /gene="lepB"
                     /locus_tag="RD451_001153"
     CDS             10548..11099
                     /gene="lepB"
                     /locus_tag="RD451_001153"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HDT7566426.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(11182..11682)
                     /locus_tag="RD451_001154"
     CDS             complement(11182..11682)
                     /locus_tag="RD451_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HDT7566427.1"
                     /translation="MNARLLSTSALLLALDVILYKIAIGPAYFQITFGFLSMALMGYL
                     YGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLFLYHKKINLPSVIAA
                     QLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQIMVVYSFIKTLEARK
                     VFKRAV"
     gene            complement(11961..12359)
                     /locus_tag="RD451_001155"
     CDS             complement(11961..12359)
                     /locus_tag="RD451_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDT7566428.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            12619..13479
                     /gene="ylqF"
                     /locus_tag="RD451_001156"
     CDS             12619..13479
                     /gene="ylqF"
                     /locus_tag="RD451_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HDT7566429.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            13472..14239
                     /locus_tag="RD451_001157"
     CDS             13472..14239
                     /locus_tag="RD451_001157"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HDT7566430.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            14295..15152
                     /gene="dprA"
                     /locus_tag="RD451_001158"
     CDS             14295..15152
                     /gene="dprA"
                     /locus_tag="RD451_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HDT7566431.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            15274..17352
                     /gene="topA"
                     /locus_tag="RD451_001159"
     CDS             15274..17352
                     /gene="topA"
                     /locus_tag="RD451_001159"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HDT7566432.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            17321..18697
                     /gene="trmFO"
                     /locus_tag="RD451_001160"
     CDS             17321..18697
                     /gene="trmFO"
                     /locus_tag="RD451_001160"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HDT7566433.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            18895..19800
                     /gene="xerC"
                     /locus_tag="RD451_001161"
     CDS             18895..19800
                     /gene="xerC"
                     /locus_tag="RD451_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HDT7566434.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            19837..20385
                     /gene="hslV"
                     /locus_tag="RD451_001162"
     CDS             19837..20385
                     /gene="hslV"
                     /locus_tag="RD451_001162"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase proteolytic subunit"
                     /protein_id="HDT7566435.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            20399..21799
                     /gene="hslU"
                     /locus_tag="RD451_001163"
     CDS             20399..21799
                     /gene="hslU"
                     /locus_tag="RD451_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002409948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HDT7566436.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            21817..22608
                     /gene="codY"
                     /locus_tag="RD451_001164"
     CDS             21817..22608
                     /gene="codY"
                     /locus_tag="RD451_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HDT7566437.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            22690..23565
                     /locus_tag="RD451_001165"
     CDS             22690..23565
                     /locus_tag="RD451_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HDT7566438.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(23697..24335)
                     /gene="plsY"
                     /locus_tag="RD451_001166"
     CDS             complement(23697..24335)
                     /gene="plsY"
                     /locus_tag="RD451_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HDT7566439.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            24462..24896
                     /locus_tag="RD451_001167"
     CDS             24462..24896
                     /locus_tag="RD451_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HDT7566440.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            25062..27107
                     /gene="parE"
                     /locus_tag="RD451_001168"
     CDS             25062..27107
                     /gene="parE"
                     /locus_tag="RD451_001168"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HDT7566441.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            27119..29569
                     /gene="parC"
                     /locus_tag="RD451_001169"
     CDS             27119..29569
                     /gene="parC"
                     /locus_tag="RD451_001169"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HDT7566442.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDRSIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            29846..32077
                     /gene="pflB"
                     /locus_tag="RD451_001170"
     CDS             29846..32077
                     /gene="pflB"
                     /locus_tag="RD451_001170"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HDT7566443.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            32321..33082
                     /gene="pflA"
                     /locus_tag="RD451_001171"
     CDS             32321..33082
                     /gene="pflA"
                     /locus_tag="RD451_001171"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HDT7566444.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            33167..34093
                     /locus_tag="RD451_001172"
     CDS             33167..34093
                     /locus_tag="RD451_001172"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HDT7566445.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            34275..35168
                     /locus_tag="RD451_001173"
     CDS             34275..35168
                     /locus_tag="RD451_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HDT7566446.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            35302..35427
                     /locus_tag="RD451_001174"
     CDS             35302..35427
                     /locus_tag="RD451_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7566447.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(35561..36193)
                     /locus_tag="RD451_001175"
     CDS             complement(35561..36193)
                     /locus_tag="RD451_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566448.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
     gene            complement(36341..36883)
                     /locus_tag="RD451_001176"
     CDS             complement(36341..36883)
                     /locus_tag="RD451_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HDT7566449.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            37018..37407
                     /locus_tag="RD451_001177"
     CDS             37018..37407
                     /locus_tag="RD451_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566450.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            37411..38175
                     /locus_tag="RD451_001178"
     CDS             37411..38175
                     /locus_tag="RD451_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HDT7566451.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            38304..39251
                     /locus_tag="RD451_001179"
     CDS             38304..39251
                     /locus_tag="RD451_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDT7566452.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            39381..40121
                     /locus_tag="RD451_001180"
     CDS             39381..40121
                     /locus_tag="RD451_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566453.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
     gene            complement(40412..41080)
                     /locus_tag="RD451_001181"
     CDS             complement(40412..41080)
                     /locus_tag="RD451_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDT7566454.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            41214..41501
                     /locus_tag="RD451_001182"
     CDS             41214..41501
                     /locus_tag="RD451_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566455.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            41917..43455
                     /locus_tag="RD451_001183"
     CDS             41917..43455
                     /locus_tag="RD451_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HDT7566456.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            43452..44417
                     /locus_tag="RD451_001184"
     CDS             43452..44417
                     /locus_tag="RD451_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7566457.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            44404..45726
                     /locus_tag="RD451_001185"
     CDS             44404..45726
                     /locus_tag="RD451_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDT7566458.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     regulatory      45789..45893
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            45967..46710
                     /locus_tag="RD451_001186"
     CDS             45967..46710
                     /locus_tag="RD451_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7566459.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     gene            46725..47717
                     /locus_tag="RD451_001187"
     CDS             46725..47717
                     /locus_tag="RD451_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDT7566460.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            47729..48466
                     /locus_tag="RD451_001188"
     CDS             47729..48466
                     /locus_tag="RD451_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7566461.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            48456..49178
                     /locus_tag="RD451_001189"
     CDS             48456..49178
                     /locus_tag="RD451_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HDT7566462.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(49262..49885)
                     /locus_tag="RD451_001190"
     CDS             complement(49262..49885)
                     /locus_tag="RD451_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HDT7566463.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNSISDINLIYSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQP
                     VVQETVQTEKQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYI
                     GRYQLDSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            50280..50971
                     /locus_tag="RD451_001191"
                     /pseudo
     CDS             50280..50971
                     /locus_tag="RD451_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
     gene            51179..51469
                     /locus_tag="RD451_001192"
     CDS             51179..51469
                     /locus_tag="RD451_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566464.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
BASE COUNT        18196 a         8905 c        10932 g        14451 t
ORIGIN      
        1 ttttgtcgca gccccatttt tttgttgtga taaaagaaca agaaaggcag gaatgggaaa
       61 gtaaacatcc ttttgtcaga aacttttatc tttcttaagt tttacttgat atctgatact
      121 atttggaata gaatgaggcg ttgaaaaatt tatggaaatt tctaactagc aataaacgat
      181 gaaacaatga aatatttttc atccaaaaag aactttgcta taatgatgga agtttgtgta
      241 taggagatct ggaaaatgag agagagtttt gaacaacaaa aaaaactgtt gcatgatcgc
      301 tatggcgccc tttcgatgga tgaccgccgt caaatacttt gtaagttgcg taaaagaaat
      361 atattgatgt atcgtcagtt ggaacgtctg aaacatgatc tgcttcgttt ggagtcaaaa
      421 cgtgtacagt gtgaattaga ggggaaccaa acacaggttg aagtagtcga aaccaaaatt
      481 ttaaagaaaa aagaacaatt tttaaaaatg cttacacaaa ataaaaaata aaggggatgg
      541 acgatggaat ttgctgagtt agttattgta tttgcagtaa cgatcacctt atcgaacata
      601 gctagccgca ttttgccaat gattccagct ccactgatcc aaattttcct tggagtggta
      661 ttaggtctga cagagtgggg acaatcaatc gattttgaac ctgaattgtt cttagttatg
      721 attattgcac cattgttatt tagagaagga gaaaaagcag atatttcttc gattctcaaa
      781 aatttcggga caattttgtt cttggcattt ggaggagtca ttttgaccct tgtcggggta
      841 ggtgcgacgt tatcattcct gttgccaagt gtcccacttg ctgcctgctt tgcttttgga
      901 gcagcgttag gtccgacaga tgcggtagca gtcagttctc tttctggacg agtgaatatc
      961 cctaaaaagg cgatgcatat tttggaagga gaaggtcttt tgaatgatgc atctggtgtt
     1021 actgccttcc agtttgctct tggtgcgctg atcaccggat ctttttcagc agtaaacgcg
     1081 gggatgagtc tagtagtttc tagtattggg ggagctttga tcggcttttt gcttgtctgg
     1141 ttcaaacaaa aaataattca tttgatcgaa aaagcatcag cacaagatgt cacagggtat
     1201 ctgctgatcg aacttttgct tccttttcta gcctatgtat tggcagaggc atttgatgta
     1261 tctggaatca ttgctgcagt ggcagcaggt attctccaag cttctggttt taggaaaatc
     1321 tctgtgtttg atgcagaatt gtcgagcttg tcccacagta catggacaac tattgctttt
     1381 acactgaatg cattagtatt tatattttta ggaatcgaat tgacgcaagt gttctcgcca
     1441 gtatggggag acggtttata tccaaacggt cttttattag cgattatcgt attaatctct
     1501 gtcatgcttt ttgtgatcag attcatttct atcagtcttt tttatgtatt caaagatggc
     1561 agtaaaaagt tcaaaaaaca gttgaacgag atcttgatct taacatttgg cggtgtaaag
     1621 ggaacagtca gtttggctac gatttttatt ttgccatttt caatcaataa tatgatgttt
     1681 taccagcggt ctttgctttt gtttctgacg gcgggtgtca tcttagtgac tttggtcata
     1741 gggatcattg tcttgcctat gctgacggaa acagaggaag cgaaaagcac ggatttgaat
     1801 gctttgatga ttttagaaga ggtcgttgaa gttttgcgaa aagaaataaa ggaaattgat
     1861 cgtaatacaa aagaattttt agccactgaa gcagtgatag aaaattatca agaacggata
     1921 cgtgatctgt acttggaaga tttaaccgat gatgaaaagc aagaagtaca agaaatacaa
     1981 gcactgattt tgtcgatcga acgggatgga ttggatgaaa gttatcgttc gggcaagctt
     2041 tcttctaatg gttatcgttt ttactcccgt tttctttctc gattcgaaca ttctatcaca
     2101 agccagattt tgtcttttat cggcttttgg ttcattgttg tccgtaggtt aatgcgaatc
     2161 gttctccatc cgaaaatgtt ttggcaaaga agatatgctg atcgtcagac atttattagt
     2221 gatgaagata tccaagaaat cagagagaca tatcaaaaaa atactcagtt gattattgaa
     2281 agtttagata acttgactga tatttatgat gaaacgatgg ttcaattttt tatccagcaa
     2341 cgcaaacttg aaggaataaa aatgaactcg gggaatttga tttcttcgtg gatgatccag
     2401 caagatagtc tgtttacgaa aaaaatgcta agaggttatt atcttgaaag aaaaatcatt
     2461 gatgaatacg aagttgctga aaaaatcacg acgttttctg cgaacagcta tcgcaggaat
     2521 atcaatttgt tagaatctta tacgatgaac aaaccatctg ataacttttc tttccgattt
     2581 gcgtttcgag caaagtcaaa aaaaacgagt ccaataaaat aaaaaggtaa aaattttcaa
     2641 gttttataaa aaacaaaaca tatcagaaca ggatcgaatc ggtcctgttc tttttttgag
     2701 aacacaaaaa gaacaaatac caaaaaaatt ttcctgaagt tcactatttt tatgatacaa
     2761 tatccaagat aaggagggaa catgttgaaa gaattaaaag taactgacct caaaaaaact
     2821 tatggtgaaa aagatttgtt tgaccagatt tcttttttgg tccacgaaaa agaccgtatc
     2881 gggttgattg ggacgaacgg gacgggtaaa acaagtctct taaatattat tgccggtatc
     2941 gatagcagcg acggtgatcg gcaaacagtg ttttatccaa ctgattaccg tattggttat
     3001 ctttctcaag cagctgaatt ttccgatgaa ttaactgttc tccaagcagt ctttcaagga
     3061 aacagcccct tgatccaaac tgttcgagca tatgaggaag cattgatcga actaggggaa
     3121 aacggagaag accctgatgt gcaaaaacgt tatgctaaag cagaagaaca aatgaataaa
     3181 gaagatgctt ggactacaga taccaacgca aagattattt tgcaaaaatt aggaatcagt
     3241 gaattagata aaaaaatcag tactttatca ggtggtcaga aaaaacgagt tagtctggcg
     3301 caagtgttga ttgatgaacc cgatttacta ttactagacg aaccaacaaa ccatttagat
     3361 tatgaagcga tcgagtggtt ggaaaactat ttgaaacaat accgtggcgc actattgatg
     3421 gttacccacg atcgttattt tctagataga gtagcaaacc gaatcttcga actttcattt
     3481 ggaaaattat acgagtataa aggaaattat gaagcttacg tcttagaaaa agcagaacgt
     3541 gatcgtgtag aagtagaaca agaagaaaag cgcaagcggc tttataaaca ggaattagct
     3601 tggatgaggg ctggcgtaca ggcacgtggc accaagcagc aagcacggat caaccgtttc
     3661 gaagatctaa aggagaactt gtaccaagta aaccaagaag atgatttaga gctgaaccta
     3721 gcgacacaac gtttagggaa aaaagtactg gaaatcaaag atggcagtta ccgtataaat
     3781 gaccaaacac tgctagaaca tttagattta ttgattcaat ctcgggaaag actaggtatt
     3841 actggtaaaa atggtgcggg aaaatcgaca ttgcttaata ttctagctgg cagaattccc
     3901 ctggatagcg gtacaatgtc tatcggtgaa acggttcatc ttgcgtatta tacacaagaa
     3961 aatgaagaaa tggcaccaga taaacggatg attgcttact tacaagaagc tgctgaagaa
     4021 gcaaaaacag cagatggcag tcaaatcgga gtagcagaat tacttgaacg atttttattt
     4081 ccaagattta tgcatgggac actgataggc aaactttcag gcggagaaaa acgccggtta
     4141 tttttgttga aactgctgat tcagcaacct aatgttttat tattggatga accgaccaat
     4201 gatttggaca tagcaacatt gacgattttg gaagattatt ttagaagttt tccaggtgct
     4261 gtgatcactg tttcccatga ccgttatttc ttggacaagg tagcagataa gttattagta
     4321 ttccaaggaa acggaaaaca agaactttat tacggaaaca tgtccagtta tttactgaag
     4381 caaaaagaga cccagcagcc tgctgaaaaa gcgaaaccaa aaatacagag caaggaacct
     4441 gctgaaaaga agaaattatc ttacatggaa caaaaagaat gggaaacgat tgaagatgag
     4501 attgcagaac ttgaagaaaa aatctcattg ctccaagaag agatgaatca tcaaggagat
     4561 aatttcactc gattacaaga attgcaaaac gacgtatctg aaacagaagc acaacttgaa
     4621 gaaaaaatgg cacggtggga atacttgagt gaatgggtag aagattagga ggaaaaagga
     4681 tggaacaagc gtatcttgac ttaggaagaa aattgttgga agaagggcat cgtaaagaag
     4741 acagaacagg cacaggcaca ttaagcttat tcggatacca aatgcggttt gatctgcaaa
     4801 aagggtttcc tttgttaaca acgaaacgag taccttttgg attgatcaaa agcgaattgc
     4861 tttggttttt aaaaggagat acgaatatcc gctatctatt acaaaataaa aaccatattt
     4921 gggatgaatg ggcatttgaa cgctacatca aaagtccaga ctataatgga ccagatatga
     4981 ctgattttgg ccatagatgt ttgacagatc ctgaattcaa tgaagaatat aaaaagcaga
     5041 gcaagctttt ttgcgagaag atcctaaccg atgattcctt tgctgaaaca tacggcgatc
     5101 ttggacacat ctacggctat caatggcgtc actgggaaac aaaagacggt ggctttatcg
     5161 atcaaatcaa acaagtgatc gaagcaatca aaaagactcc tgattctaga agattgatcg
     5221 tttctgcatg gaatccggaa gatgttccta gcatggcttt gcctccttgt catacgatgt
     5281 ttcaatttta tgttcaagag ggacggctaa gctgccaatt gtatcaacgc agtggggatg
     5341 tgtttctagg cgttccgttc aacattgcaa gttatgcgtt gctgactcac ctaattgcac
     5401 atgaaacagg tttagcggtt ggcgaatttg ttcacacatt aggagatgct catctttata
     5461 tcaatcatat cgaacaaatg aaagaacaat tgagccgaga aatacgcgca tttccgactt
     5521 tagttttgaa tcaggaaaag cagtcagtat ttgattttga gatggaagat atccaattag
     5581 aaggatatga cccacatccg gcgatcaaag ctcctatcgc tgtttagaat cagaaaggat
     5641 gagaaaatgt tagctgcaat ttgggcacag gatgaaaacg gattgattgg aaaagaagac
     5701 cgtcttcctt ggcgtttgcc aaatgatctg aaattcttca aacaaatgac agaagcaaat
     5761 acactagtga tgggacgaaa aacattcgaa gggatgggta gccgtccgtt gccgaatcgt
     5821 cagacgattg ttttgacgag agattcttcc tataaagcag aaggcgtgca tgtcatgcat
     5881 agtgtggaag acgtgcttgc tctggaaaaa gaaacagacg gtatcttttt catcgctgga
     5941 gggtcagctg tttatcaaga atttctgcca ttttgtacga tattataccg tacagtcatc
     6001 catcatgtat tcgatggaga tgcttatttt ccacctgttg actggtctga ttggtcactg
     6061 atcaatacta gtcaaggaga aatggatgaa aaaaatcgtt atccgcatca atttgaaacg
     6121 tatcagcgta atgagaatcc tgtaaaaagc gggacaggcg aattgacgat ataaaaaagc
     6181 tatggataga ctagctgtta tttagagctg tcccatccat agctttattt tttttattaa
     6241 gtaaagaata aaacagagaa gtacataaaa cctgcaccta acataacaaa caaatgccaa
     6301 acaacatgca tatagcggat agaattcaag ctataaaaga atgcgcctat cgtgtaagaa
     6361 agcccgcctg ctaccatcaa aataacacca gtcattccaa gagagtgata aagaggaaca
     6421 gcagccacga cacagagcca ccccataaaa atatagatga tcgtagatac ttttgatact
     6481 ctctcccgtt tatgcaacgt caacgcttta tatataatgc caagaatcgc aaacaaccag
     6541 attaatacaa ataaagtcca acctagccat cctcggatac tcagcaaaca aaaaggagta
     6601 taacttcctg caatcaaaag aaaaatcgaa ctatgatcga atacttggaa cacctttttt
     6661 gcttttgtaa aaatcaatga atgaaacaaa gtagacgtta aaaataaaag aatcatcatc
     6721 gatccataga tagcataaga gacaatatgg agggaggaat gcaagtgggc accttttact
     6781 aaaagaacca ctagtcccgc gatactcaat ccagtcccaa ttccatgggt gactgcatta
     6841 aacacttcat ttaatatttc atacgttcga ttaaatttcg ttttttccat gaaaacggct
     6901 cctttactag gtgtaattaa tgaaaaatca ttatttgtct gttatactaa aaatagaaat
     6961 tgtcttacat gtagtttaac atgaataagg catcttgtta aagaaagaga gagagaaaat
     7021 aatgacaaat gtaaaaatcg taacagattc ttcatgtacg atggaaaaaa atgtacgcga
     7081 tgctttaggc attcgtgtca tgccgctatc catcatgatc gacggaacag tatatcccga
     7141 tgatgaccaa ctagacggcg aaagatttat ggaaatgatg gcgaaagcaa aaaatctgcc
     7201 caaaacaagc caaccaccaa ttggagaatt catctcgatg tatgatgagc taggagaaga
     7261 cggcagtgaa gtgatttcga tccatatgac aaaaggcttg agtggaacag tagaagcagc
     7321 aagacaagcc agtaatctaa caaaaacgaa agtaacggtt atcgacagtg ataccactga
     7381 ccaaggatta tcttttcagg taattcgagc agctgaatta gcaaaagaag gtaaaacagt
     7441 agagaaaatc cttgaagaag tcaaaaaagt acaagacaat acaaaattat acatcggaat
     7501 atccacacta gataacttgg taaaaggtgg aagaatcagc cgaacaactg gtttgctgtc
     7561 tagtgttttg aacatacgcg tggtgatgaa tttcgcccat tctgaattaa tccctgtaac
     7621 taaggggcga ggaaagaaaa cgttcgataa atggtttaat aatttgaaaa atgaactgaa
     7681 agaattgcca aatgtgcgac aaatcggtat ttcacatgcg gatgcaaaag aattggcgca
     7741 agaattcaaa gagggtttgc aagaattatt cccggacatg catatccctg tactgcatac
     7801 gaatccggtt atcgctacgc atactggtaa agacgcgttt gcaatcatgt attatgtaga
     7861 ttagtcgaaa agaggataag ccctcagcct gaaaggcttg cagcttattc tctttttctt
     7921 tataaaatta ggaaaataat tgttttcttt tttcataaag actacctttt tgataaaatt
     7981 tttgataaca ttagaaccaa tcgaatacaa gaggtgaaaa aatgaaatta acgaaacgac
     8041 atttgatcct cgttttgttc ccattattaa ttgcgatcat catctatgca ggtttagctg
     8101 cttctatacc gaaagctggc ccactaatga aaccagtaac tactgtgaga gaagatccaa
     8161 ataaaaaaga aaaacttcac tacatagcta tcggagattc gctgactgaa ggagtaggag
     8221 atcaaaccaa gcaaggagga ttcgttcccc ttgtcgcaaa tgatctaaaa gaccgttata
     8281 atttgaccgc ggttgaaaca gaaaactatg gtgtaaatgg tgaacgaagt gaccagatct
     8341 taaagcgagt aaaaacaaaa gaagaaattc gaaacaatat caaaacagct gattttatca
     8401 cactgactgt tggcggtaat gatttgatga aagttatcca aaataattta ttcgggttaa
     8461 cggtcaattc ctttaaaaag ccactgaaaa actatcagga aaatgtcaca gaactattgg
     8521 aagaatttcg atccctcaat aaaaccgcac ctatttacat tttaggcatc tacaatccat
     8581 tttatttgaa ctttcctgag atcactgaca tgcagacaat tgttaacaat tggaacaaag
     8641 gaacagaaac ggtgacaaaa aaaatgccga actgctactt tatcccaatc aatgatttgc
     8701 tttatcaagg attgaatcag gaagtaggtg tcacagaaga aggaacagat caaacaacta
     8761 gcacgacaga aaatctaaat ggcatcaaaa ataatgtgct ctatgaagaa gatcatttcc
     8821 atccaaataa tttaggttat caattgatgg caaatgcagt gagagatcag ctgatcgaga
     8881 cacaaaacca atggttagag aaggaggatg atcaataaac atgaaaacaa gatctgacgt
     8941 atcttcaaac aaaacaaaga aaacaaatta ctggaaattc gccttcctta tccttcttgg
     9001 ggtagtactt ggttcgaccg tatttttagg cagccgtatt tttgctaatc gggaaccaga
     9061 actcccagaa ataccagctc ttacggaaag acaaggagat cctgtcttaa cgatcaattc
     9121 aaataaagaa aaagtcaatc aaatcatcag ctttttcctt agtgagtatc aaaaagatag
     9181 tgatattgaa tataaatttt atttggaaaa tgaagcacta ctcaatggta ctttcgaagt
     9241 actaggtttt cctatcgatt tctatttata ttttgatccg tatgtgatgg aaaacggaaa
     9301 tgtccaacta aaagctagaa gtctttctat cggaacattg agtttgccaa tcaaagatgt
     9361 gatgaatatg atcaagagaa actataaatt accagattgg atcgaagtca atacagatga
     9421 tctgactatc atgcttaggt tggatcaatt ccgaatgcaa aacgggatgt atattaaagc
     9481 agataaaatc gacttagtaa atgatgacat tcggtttagt ctatatttgc caaaagatac
     9541 ctctgatgct tcaaacaact caaataccaa caaaactagc accagcagta ctgaaagcaa
     9601 gacaaaagaa aataaaaaat catcggatga gtagtattag agggggaatc ataatggaac
     9661 gagcaatatt tgcaggaggc tgcttctggt gtatgatcca gcctttcgac acgcttcctg
     9721 gtatccatac agtgatgtca ggatatactg gagggcatgt accagatccg acttatgaac
     9781 aagtaaaaag ccaaacgact ggacatacag aagcagtgga gattatctat gatccaacat
     9841 tgatttcata tgaacaatta gtagaacttt actggcagca aactgatcca actgacgctt
     9901 tcggacaatt cgaggatcgc ggtgacaatt atcgcccggt gatcttttat ttgacagaag
     9961 aacagcggat cattgctgaa aaaagtaaga aacagttagc tgaaagtgga cgtttcgaac
    10021 agccaatcgt tacaaaaatc gaaccagccc aaccatttta tctagcagaa gaagaccatc
    10081 aagactatta taaaaagcat cctgaaaatt ttaaaagaaa ccatgcacgc cgggctgcct
    10141 ttatcgaaga aaattggagg aacgaagggt gaatcgaagc ttttttcatt atttaatgac
    10201 actgcgaggc ggtggcacac atgatgcttt atctgttttc gctacagaag ccggtaaaga
    10261 catccaattt cctaagcaca gctctagcta cgaagaaatt tctaattatc tggaactgaa
    10321 tgtcgactat ttgccgtcca tggatatctt tgacgaagca tgggaaaaat atttagaaaa
    10381 taatcatgac atataagaga tagttttgta ctttatgatc aaaaaagttt tttgtccaat
    10441 agcctaattg aaagaattat ttttatttca gctatctagt cgcatttttt tgatattttt
    10501 cttataataa agaaagaatg aaaaaaagag ggatggattg atagagattg acaaaaaaac
    10561 aacgctatat taatcgcttc tggcttgtat tcaaatactt acttgtttct gtattccttg
    10621 cgttcatgtt gcggggattt ttattcatcc cggtaccagt ggaaggcaat tcaatggaaa
    10681 acgtgttgaa gcaaggtgat atggttgtga tggaaaaatt ttcggagatc agacgatttg
    10741 atattgttgt ttttcaatta gcagatggca cgatttatat caaacgagta atcggtcttc
    10801 caggagaaaa tgtcagctac caaaatgatc aattgaagat caatgggaaa gtagttaagg
    10861 aaccttatct aactaaaaac ctgaaatcag atcatgcaaa tgcatcctat acgacggact
    10921 ttacactaca agagctaacg ggacaatcca agcttccgga agataattat tttgtacttg
    10981 gagataatcg aagagtttca aaagatagtc gttcgtttgg cacgatcaat aaaactgata
    11041 ttctaggtaa agcaagattt gtctattatc cacttgatga aataaaatgg atccagtgag
    11101 aaacaataaa gcgtgcagtc tgttgagact gcacgcttta ttgtttaatc caaaatcagt
    11161 ttactacctt agtacgtaaa atcaaacagc tcgtttaaac acttttctag cctctaaagt
    11221 tttgataaat gaataaacaa ccattatttg aatagggatt tggatcatat tcctgatgaa
    11281 tctacctaga aaaattactt tgaaatctgc accaaacaaa acagacatca gccaagaatt
    11341 gataaaaagg ctgactggga tcataatcaa taattgggca gcgatgacgg aaggcaggtt
    11401 tatcttttta tgatataaaa ataagccatt aataaatcca ccaaggaaag ccgtgataag
    11461 aaaagcagct tgaaacgttc ctgaaccaaa tatcgtgaaa tttaaagtgt tcgacaacat
    11521 ttcaagcaaa ccagcccaga tcggtccata tagataaccc ataagcgcca tacttaaaaa
    11581 tccgaatgtg atttgaaaat aagcaggacc aatcgctatc ttgtataaga tgacatcaag
    11641 ggctaataaa agagcagagg tcgacaacaa tcttgcattc atttcgggca atctaaaaac
    11701 gtcttttgca atcaaagtgt tcaaaatatt ctctcctttg tcagttaata ataaaaggat
    11761 accataaaat caccaatgtg tcatgacaca ttggtgattt acatacactg gcatctaaca
    11821 attaaaaaaa gggtgagaag actgctttta taaactgtaa aaaagagatt gtacgaataa
    11881 aaaaaataga ggcggagaat acttatcgta tcatccgcct ttgttttttt gttataaaaa
    11941 acgtcagatt agttatctgc ttacatcttc atccatacgg gttctaatgt atttccgtct
    12001 agatcttgga cttctaatga aaacatttct tcttcaggca ttcccatatc tacttcgtgg
    12061 aaagtaccac cattttcttt tgcaatttga gcaaattttt ttacttcatc cgcattttca
    12121 acactaaacg aaatcaaagc accacttgtt tttttattat cagctatttc tttatctttt
    12181 ataaattttt tataaaaatc atgagagaga agcattatcc aaaaagtgtc atcccatacc
    12241 attgaaccag cttcttcagt agaaaattct tcattttttt taaaacccag cttttcataa
    12301 aaagcaacgg aacgattgac atcagcaaca ggaaaattaa caaaaaccat actattcatt
    12361 tgtttcgtct cctttctgtt ttgttcgtct atcatctctt atttaggaaa cgctgtcaaa
    12421 aatttagatt catatataga aaccaaaata aaaatttgca tcatcaaaaa agtgaagatg
    12481 tgatagaatg aggactggtt cactttcact taactaatag atggaatttc tttataataa
    12541 aaaagtgaat ttatattgaa aaagaaaaaa acaagtaaag ccggggaata ttccggtatg
    12601 aaaggaatgg agagaacaat gaccatccaa tggtttccgg gacatatggc aaaagcccga
    12661 cgagaagttt ctgaaaaaat gaaatatgtg gacatcgtat ttgaattggt agacgcacga
    12721 ttacctttat cttctcgtaa tccaatgcta gatcagatca ttcagcaaaa acctcgcctt
    12781 gttttattga ataaagcgga tctggcagat ccacaacaga caaagctgtg gcaagaatat
    12841 tttcgtaaac aaggccatct tgcattagct atcacggcac aagaaagtaa aggaattaaa
    12901 ggtctagtac ctgcggctaa agaagcattg aaagaaaaac gggcaagaga tgctgctcgg
    12961 gggatcaagc ctcgcgctat tcgggcaatg gtcttaggta ttccaaatgt tgggaaatct
    13021 acgttgatga atcgactagt aggcaagaaa attgcacaga caggaaataa gcctggcgta
    13081 acaaaaggtc agcagtggct tcgtttaggt aatgagttgg aattgttaga cacaccaggg
    13141 attttatggc ccaaatttga agatgaagaa atcggcaaaa aactagcgct gacaggcgcg
    13201 atcaaagacc agcttgtcca tttagatgat ttagcgattt acggattaga cttttttgcc
    13261 cgatattatt caggaagaat cagcgatcgt tatggtttat caatcgagca agaagaaaaa
    13321 ttggcaccgg aattactgat ggatattaca gcaaaacgtg ggtataaaga agactatgat
    13381 cgtggcagcg aattagtcgt gcatgatatt cgtcaaggaa aacttggacg atacacactg
    13441 gatcgttgcg aagaaatgga gcaaaaaagt gatgactgaa tccatccaaa gtatcaaaga
    13501 acgattgaaa agcatacaga gaatagatga tcctacacta gaatcattaa gaaatgatcc
    13561 acgcaaaggc gtgcagcaag cactggcttc ttttgaacga cgattgaaaa aggaagcatt
    13621 aattaaggaa aaatatgaag aaatgttttg ctttgaaaag caagggtacg cacaaggtca
    13681 ccaatggatt gccggcattg atgaagtagg aagaggacca ttagctggac ctgtcgtggc
    13741 agctgcagtt atcttgccga aaaatgagat catattaggg ctgaatgact ccaaacaatt
    13801 atcagagaaa aagcgagaac ttctttatca acaagttcaa gaaaaagccc tggcaatcgg
    13861 gatcgggatc gttgatcagc agacaatcga tgatgtgaat atttatgaag caagtaaatt
    13921 agcgatgatc caagcagtag aaaaattgtc cattgtacca agctatttgt tgatcgatgc
    13981 gatgaccttg gatttgccta ttcagcagga aaaaataatc aaaggggatg cacgatctgt
    14041 gtcgattgct gctgcaagta tcattgctaa agtatatcga gaccaattga tgaaagaata
    14101 tgacgtgctt tatcctggat atggtttctc gcataatgca ggttatggaa caaaggaaca
    14161 cttagaagga cttgaacgac aaggaattac gccaatccat cgtaaaagtt ttgcacctgt
    14221 aaaaaaatat ttacaataaa aaacagccgc ttttacgtat cttattagaa agagagacga
    14281 aaggcggttt tatgatgtat caaatagaag aaaatttatt gaaacttgct tatacaaaag
    14341 gaatcagtag tcaaggaaaa tgggcacttg ctaactggat gatgcagtat ccttataaag
    14401 aaatcggatt tgaagacatc attaagatag gtaaaataac caaacaccgg gagctgtttc
    14461 gcaaaagttg gcaggaaatt cacgctaact ggggcaaaat ccaatcgaaa cagtcgttta
    14521 tcacttgctt tgatcccaaa tatccccctc agctgcttca cttgacctat ccgccaattg
    14581 tactgtttta taatggtgat ctatctttac tttcttgtaa catgttaagc gttgttggtg
    14641 gaagacacac ttctgcttta gccaaaaaaa cagtttatta tttactaaaa ccagtgatag
    14701 aagctggata tgtgatcgtc agtggctgcg cgaaagggat agatacatac ggtcaccaag
    14761 cagcaatctc tcatggtgga cggacaatcg cagtcattgg aacagggata gagcaagtct
    14821 atcctgctga aaatcgtgac ttgcaagagg tgattgcaaa tgatcatctt cttttgagtg
    14881 aatatcctcc tcaatccggc ccgaaaaagc attgttttcc aatgagaaat cggattatcg
    14941 cagctttgtc taaaggaaca tgtgtctttg aagccaagaa aaaaagcggc tctctgataa
    15001 cagcacagca agcattggat cttggaagaa cagttttttc tgttccagga aatattttaa
    15061 cagaacattc taccggatgt catcatttga tccaagacgg tgcagtttgc acggtttcgg
    15121 gtgaagatat cttggcagaa tttaaagaat aacaccatac ttttcatttg cttttcttga
    15181 caaacgtttt ctgaatggat atgattagct acgatttgta tgaatcctct tttaatagta
    15241 ggaacacgac aatggaaagg agtccattca gtaatggcgt ataaatattt agtgattgta
    15301 gaatcacctg caaaagccaa gacaattgag aaatatcttg gacgaaacta taaagtaatg
    15361 gccagtgttg gccatataag agatttaccg aaaagtaaaa tgggtatcga ttttgaaaac
    15421 aattatgaac cccattatat ttctatacgc ggaaaaggcg atgtcatcaa aagcctgaaa
    15481 gccgcagcaa aaaaagctca aaaagtttac ttggcaagtg acccggatag agaaggagaa
    15541 gcgattgctt ggcatttagc gtacctactt gggttggatc tgaaagaaaa aaatcgggtg
    15601 gtcttcaatg aaatcacaaa agacgcagtc aaagcagctt ttaaggaacc aagaacgatc
    15661 gatgtagatt tagtagatgc acagcaagct cgtcgtacct tagacagaat cgttggttat
    15721 tcgatcagtc ctattctctg gcgtaaggtc aagaaagggt taagtgcagg acgtgtccaa
    15781 tctgtcgctt taaaaattat tattgaccgt gaaaaagaga tccgagaatt tgttccagaa
    15841 gaatattgga gcatcgacgg taattttaaa aaagctcgca agaaattcaa agcaaatttc
    15901 tggggaatcg acggtaagaa aaagaaatta ccagatgcac aaagtgtaaa agaagtcact
    15961 gctagaattg atggaacaga cttcgaagtt aaaaaagtag aaaagaaaga gcgcaaaaga
    16021 aaccctgcga atcctttcac tacaagtagc ctgcaacaag aagctgcccg taagttaaac
    16081 tttcgaacaa gaaaaaccat gatggtagca cagcaattat atgaaggaat cactttgggt
    16141 aaacaaggaa cagtcggctt gattacatac atgcgtactg attctacccg gattgccgat
    16201 acagcaaaag cagaggccgc agcatttatt gaagatacgt atggaaaaga attttctaga
    16261 catgatcacc gaaagatcaa aaatgctcaa ggcgcacaag atgcccatga agctgtgcgt
    16321 ccaacgagtg tgcttcgtac accagatgaa ctcaaacaat atttagataa agatcaattg
    16381 aaactttata cattgatctg gtcacgtttt gtggctagtc agatgacacc agctatttta
    16441 gatacaatga aagtgacatt agaacaaaat ggtgtcatct tcattgcgaa cggttcaaaa
    16501 atcaaattca aaggattcat gcaagtgtat gtggaaggta gagatgacgg caaagaagag
    16561 aaagaaaata ttcttccaga acttgaagaa ggcgatgtag tccaatctgt tgatattgaa
    16621 ccaaaacaac attttactca accaccagca cgttttagtg aggctacgtt gattcgtgca
    16681 ctagaagaaa acggggtagg gcgaccttcc acttatgcac caacacttga tacgatccaa
    16741 agacgctact atgtaaaatt gacacaaaaa agatttgagc cgactgaact aggagaaatt
    16801 gtcaattcat taatctgtga attcttccct caaatcgtcg atatccattt cacagcagaa
    16861 atggaaggag atttggataa aattgaagaa ggcacggaag cgtgggtcaa agtggttgat
    16921 cgtttctata aaccgtttga aaaagaactg acgaatgcgg aagaaaaaat cgaaaaaatt
    16981 caaatcaaag atgaaccagc aggattcgat tgtgatgtct gtggacatcc gatggtgata
    17041 aaattaggga aatatgggaa gttttatgct tgcagtaatt ttcctgattg tcggaatacg
    17101 aaaccaatcg taaaagaaat cggtgtgact tgcccagtat gtcatgaagg acaagtcatt
    17161 gaacgaaaat ctaagaaaaa cagactattc tatggttgtt cccgtttccc agaatgtgaa
    17221 ttcacttctt gggataaacc agtgggcaga aattgtccaa aatgtgacgg atatctggtc
    17281 gagaagaaag tcaaaggcgg taaacaagta gtctgtgtaa atggagatta cgaagaagac
    17341 atccaaaaat aatagaaaag aggttctttc attgaaaatg gtaaatgttg ttggagcagg
    17401 gcttgccgga agtgaagctg cttggcagat cgcacaagca ggagtccctg tccgtttata
    17461 tgaaatgcgt ccagtcaaat cgactgaggc gcatcacaca agtaattttg ctgaactagt
    17521 atgttccaat tcattaagag gaaacagttt ggctaatgca gtagggttat tgaaagaaga
    17581 aatgcgccga ttgaattcgg tagtaatcac ttcggcagat gaaacagcag tgccagctgg
    17641 tggtgcctta gctgttgacc gcgattcttt ttctgaaaca attacccgaa aagtcaaaga
    17701 gcatccatta gtaacagtga taaacgaaga aattactgaa ataccggaag gaatcaccgt
    17761 agtagcaaca ggacctttga cttctcatcc attagcagaa agcatcaaag cattcaatgg
    17821 ttcagatggt ttttatttct atgatgcagc tgcaccaatc gtagacaaag ctacgatcga
    17881 tatggataaa gtatatttga agtcccgcta tgacaaagga gaagcagctt acttgaactg
    17941 tccgatgaca gaagaggaat tcaaagcttt ccatgaggca ctaatcaatg ccgaagtggc
    18001 agaacttaaa tcttttgaga aagaaaaata ttttgaagga tgtatgccaa ttgaagtaat
    18061 ggcacagcga ggattcaaaa cgatgctttt cggacctatg aaaccagttg gattggaaga
    18121 tcctaaaact ggcaaacgtc cttatgctgt tatccagctg cgtcaagaca atgctgcagc
    18181 ttctttatac aacatcgtgg gctttcagac tcacttgaaa tggggcgagc aaaaacgtgt
    18241 tttccggatg attcctgggt tagaaaatgc tgaattcgtt cgctatggtg tgatgcaccg
    18301 aaacagcttt atgaattcgc cagaattgct gaaaccgact taccaatcaa cgaaacgcga
    18361 agatctgttc tttgcaggtc agatgactgg tgtagaaggc tatgttgaaa gtgcagcgag
    18421 cggactactt gctggaatca acgccgcacg cttagcaaaa gaaatggaac cagtcgagtt
    18481 tccacaagaa acagctattg gaagtatggc ttactacatt actcatgcgg aaggaaaaca
    18541 tttccaaccg atgaatgcca actatggtct gtttcctgaa ctgccagagc gcattcgaga
    18601 caaaaaagca agatatgaag caattgcaca acgagcttta aaagctaatg aggcaataaa
    18661 aacagaatta gaaaaaactg caatcccaaa tgagtaagga aactccatga agagggtgag
    18721 acggatagtc tcgctctttt tcttgcgttt ttcttaagaa tttctcaaac aaaatgtgag
    18781 gaattgcgcc aattgtgaac aaacttagaa atattggtta aattctgaca atttatttgt
    18841 ctttttataa acgctgtgct aaattattct ctgggacaaa aggaaggtga gaaaatgaca
    18901 gaagccacgt gggaacaaaa atttttgcgt tatttgattg tcgaaagagg atattcagaa
    18961 aaaacgaaag aagcatatga agaagacatt ctccatttca aacatttttt ggaggaatct
    19021 ggagacgctg atctgctgaa ggcggaatat tttacggttc gtgtctattt gagtgcatta
    19081 gctgatcatc gtcctagcta tagcagaaat tctatcagtc gcaagatagc cagcctacgt
    19141 tcgttttatc agtatcttct caaagaagaa gtgataaaag aaaatccatt ttcttacgtt
    19201 catctcaaaa agaaaaattt gagactgcca cgtttttttt atgaaaatga aatgcaagca
    19261 ctttttgaca gcgtagcagg agatagtcct ttggatttga ggaaccgcgc tttactggaa
    19321 gtcctttacg ggtcaggcat ccgtttaagt gagtgtagca gtttgtcggt atcagacatt
    19381 gattttgatt cagaggtcat gttgatccat ggtaaaggga acaaagagag atatgctcct
    19441 ctaggttctt ttgctcaaga tgctctgcaa gaatatttca gggaaggccg ccaggtattg
    19501 atgacaaaat atcacgaaga gcatgatatc gtttttgtga atcatcatgg aaaaccaatc
    19561 acgcctactg gaattgaata tgtcttgaat caaatgatca aaaaaagcag tttggatagt
    19621 gatatccatc ctcacatgct gcgccataca tttgctactc atttattaaa taatggggca
    19681 gatttgcgga cagtccaaga attgctagga catgccaatt tatcgactac ccagatctat
    19741 gcccatgtaa caaaagaaag tttacaaaaa aactatcgtt ctttccatcc aagagcgtaa
    19801 aaataaggaa aagaacaaat ttaggaggaa acaaacatgg tcgaatcacc atttcattca
    19861 accactatct gtgccgtcga aaaagacggg aaatttgcta tggctggaga tggccaagta
    19921 acaatgggtg aatctgttgt catgaaaggc actgcaaaga aagtacgacg tatctacaat
    19981 ggagaagttg ttgtaggttt cgccggaagt gttgcagatg cgtttacttt agaagaaaaa
    20041 tttgaaggca aactaaacga atataacggg aatctacaac gcgcagctgt cgaattagct
    20101 caagaatggc ggacacagca atctatgcaa aaacttgaag cgatgctgat cgtaatgaat
    20161 gataaagaaa tgcttcttgt ttcaggtaca ggagaagtta tcacaccaga tgatggtatc
    20221 ttagctatcg gatcaggagg gaattttgcg ttggctgcag cccgagcaat gaaaaactat
    20281 gctcaaaacg acatgagtgc gaaagaaatt gcagaaaatg cgttaaatat tgccgcagat
    20341 atctgtatct ttactaatca taatattatc gtagaagaac tgtaagaggt gagtagatat
    20401 gtatgaatta aaacaaacac caagacaaat cgtaagtgaa ttagatgaat atatcgtagg
    20461 acagcacgca gcaaaaaaat ctgttgccgt tgctttgcgt aaccgctatc gccgtttgca
    20521 gttagatgaa aaaatgcaac aagatattac accaaaaaat atgctgatga tcggacctac
    20581 aggggtcggt aaaacagaaa tcgcacgacg tttggcaaaa atcgtcaatg caccatttgt
    20641 caaagtcgaa gcaacaaaat ttactgaagt cggttatgtc ggaagagatg tagaatcaat
    20701 ggttcgggat ttagtagaaa atgcgatcca aatcgtagaa aaagagcagt acagccgtgt
    20761 atacacaagt gctaaaaaaa atgcagaaaa acgtttggta aaaatcttgg tacctggtat
    20821 caaaaaagaa cagaaacaat ccactaatca atttgaacaa atgatgaatc tttttaatgc
    20881 tagtcagcaa aataccgctg aaccgcaaga agaagtgaca gaagatattc gaatcaatcg
    20941 ccgtacagtc ttggaacaac tacaaaaggg tttactggat agtcgtgaag taaccattga
    21001 agttgaagac caaaagaaac ctgcaccaat gatgaacaat ggattggagc aaatggggat
    21061 cgacctaaat gaaactctag gtgctttgac accgaagaaa aaagtggaac ggacggtaac
    21121 agtcaaagaa gctttagagt tattgatcaa ggaagaatca gcaaaattag tcaaggatgc
    21181 tgatatccat agtgaggcaa tcaaattagc ggaagaaagt ggaattattt ttatcgatga
    21241 aatcgataag atcacttcta aatcacagca atctggagaa gtatccagag aaggcgtcca
    21301 aagagacata ttgccaattg tcgaaggttc acaagtaaac acaaaatacg ggatcatcca
    21361 aacagatcac gtcctattca ttgcttcagg agctttccat ttgtctaaac caagtgatct
    21421 aattccagaa cttcaaggac gcttcccgat acgggtagaa ttagatgatt tgacagctga
    21481 agattttgtg aagattctga ccgaaccaaa taatgcttta gtaaaacaat acgtcgcgtt
    21541 gatcggtaca gaaaatgtgt cagttacgtt tacaaaagaa gcaattgaac ggatcgctca
    21601 aatcgctttc gatgtcaacc gtgacacaga taatatcggc gcacgcagac tgcataccat
    21661 tttggaaaaa ctactagaag atctattatt tgaagcacca gatatgcaaa tgggagaaat
    21721 aacgatcaca gaagcatatg tggatgacaa acttggctca attgcggcaa atgaagattt
    21781 aagtcgctat attttataaa aaatcggagg acgacaatga cagacttgct aacgaaaacc
    21841 cgcaagataa acacactttt gcagcaaaag aatacttttg acatgcaagc agatttgcct
    21901 tacgataaaa tggctgtcac actaggtggt attcttgaca gcaacaccta tatcatagga
    21961 agtgacggag tattactagg ttataatgaa cgtcacgatg tgaacaatga acgaatcaaa
    22021 acaatgtttg ttgagaaaca atttcctgaa tcttatactg atacagtggc acagttgatg
    22081 aaaactgaag ctaatatccc aattactagt gatattactg catttccggt agagtcaaga
    22141 gagaaatatc catttggtct gacgactgtc gttccgatct ttggagctgg cgaacgtttg
    22201 ggtacgatta tcttatctcg tatggaacaa tcgtttgcag atgacgatct agtcttagca
    22261 gaatatggag ctacggttgt cggtatgcag atcctttatc agaagtctcg aagcatcgaa
    22321 gcagatgtac ggagtgcaac ggctgtccaa atggcaatca acacattatc ttatagcgaa
    22381 ttgaaggctg tacaagctat ctttgaagca ttggatggag atgaaggtcg tctgactgct
    22441 tctaatattg ccgatagtat cggcatcact cgttctgtga tcgtcaatgc tttacgaaaa
    22501 ttggaatcag ctggaatcat tgaatctcgt tcgttaggca tgaagggaac ttatttaaaa
    22561 gtattgaatt cccgttttaa agacgagtta gcaaaacaca gttattagaa gtaaggggac
    22621 tggggcagat agaaatgttt gttccagcct tcccatttta aaaagtaagt cgaagttgga
    22681 ggaatggcaa tgactgttat tattcaaaat gaccagctga tcgccgaaat cgctgaacac
    22741 ggtgcggaat tgatcagtct gaaatcaaaa gaacatggtt tagagtatat ctggcaaggt
    22801 gatccagcgt attggggcag acatgcaccg gttttattcc cttttgttgg acgtttaaaa
    22861 gatgatcagt atgtttatca agggaaaaca tatcaaatgg ggcaacacgg atttgctcgg
    22921 gatatggatt ttgaagtcat tgaacatgga caagaaatgg ctagtttcat cttaaggagt
    22981 acgccggaga cattagaaaa gtatccattt gattttgaat tagtgatcag ctatgaatta
    23041 ggaggagacg gcatcacggt tcattatcaa gtggcaaata ccggtgaaaa agaaatgttc
    23101 ttttctatcg gtggacatcc tgctttcaat gtacctcttg aagaaggatt gtcatttgaa
    23161 gatttctatc tggcattttc tccattgaaa tcaagattac gcctaccatt gaaaggccca
    23221 ttcatcgata tggatcaaaa gacgttaggt cagacaaata cgaatctggc tttgaatcgt
    23281 gaactttttg agcaagatgc cttggttttt gaaacaaggg gtctaaatgc gtacgccatt
    23341 cgaagtgaaa aatcttccca tagcgtaact ttaagctata aagatatgcc ttatgtaggg
    23401 atctggtctc cttatccaaa agaagcgcct ttcgtttgta tcgaaccgtg gtgcggaatc
    23461 gctgacacgg tgaacagtag tggaaacttg atggaaaaag tagggatcaa tcaactaggt
    23521 gcccatgaaa tcttcaagac aaaatattcc atcacagtga agtaagaggt tgtgaccgag
    23581 aagttagcag ggaacaccgt ttaccaaggt gtgtaaaaaa gctatcctgt aagtaataag
    23641 ggagtgtgac atcgatttgt cacactcccg ttttatctct ttggaatgaa aaagtatcag
    23701 gattttttct tgctgctatt caaaccaaac gggattcgac tttcagtatg gtttctgata
    23761 cgcttgatat tgtctttatg ccgataaaag ataaaggaag aaactaaaaa ggcaatgatc
    23821 gtcagtaacc aattgggctt agccaaaatc acaggagcta cataaggaag gacgatcgta
    23881 gataaagtga tcaatactgc actgatcata ctgctcaaac tcaccatact tgtacaaaat
    23941 aaactaacga taaagatgat acaagaataa acaaaaaata caggattaaa tcctaaaagc
    24001 attcctgcac ttgtcgcaac agcttttcct cctttgaacc cagcaaaaat cggaaatgta
    24061 tggccaagaa tggcgcatac cccaaaccaa agagggttaa tcccagaaag gtggaagatc
    24121 atcggcaaac aagtagccaa tgtacctttt aaaatatcca taagcaggac aacaatcccg
    24181 gctgttttgc ctaatacacg aaatgtattg gtcgttccag tattaccgct cccgtgttgt
    24241 cggatatctt ttttgaaaaa caatttgcca atccagacac cggaaggaat agaacctaaa
    24301 agatatgcta aaataagtaa taagatcaat ttcatttttt accctctttc aagttgaaaa
    24361 ctatccttta ttttagcatg aataggtaac aggaacaatt gaaaaaatga aagatacaag
    24421 tataatagat ggaataaaaa gaaaagcaag gggtggcaga aatgtctgta aaaaatccaa
    24481 cacaagaaac gattttcaac tatttggaag aagcaaaaaa tattgccgtc gtaggcttga
    24541 gcaataaacc agaacgaaca agttacatgg ttgcacaggt attgcaagac aatggatata
    24601 aaatcatacc agtaaatcca ttattggctg gtgaagaaat tctaggcgag aaagtctatg
    24661 cgaatttgac agaaatcgat gatccaatcg atatcgtaga tgtatttaga cggagtgaat
    24721 ttttacctga aatagcaggt gattttttga aaactgatgc taaagtgttc tgggcacaat
    24781 tagggattga aaacaaagaa gcagctgaga tgctaagaaa agcaggacgt acagatatcg
    24841 taatggatcg ttgtattaag attgaacttg gtaagttgaa agaaaaccaa aaataaaaat
    24901 gaccacaaag aagagatgat cgatagaggg gaatgtcgaa aaagcggtta ggagataatt
    24961 aaaattgatt tctcgtctac cctctttttt ttcacgacct tttctagtat gataatcgtg
    25021 gtgcggtttt gccgcaaagt attattgaag gagcgtttgc cttggcaaaa aaagtaaaca
    25081 acgaatacaa tgactcgtcc atccaagtat tggaaggatt agaggcagtt agaaaaagac
    25141 cagggatgta cattggatcc actgacagcc gaggcttgca tcatttagtc tatgaaatcg
    25201 tcgataatgc agttgacgaa gcattatcag gttatggcag tgagattgat gtgaccatcc
    25261 atgaagacaa tagtataact gttgcagata gcggacgtgg gatgcctgta ggaatgcatg
    25321 cttccggaat accaacagtt gaagtgattt ttactgtgct gcatgctggc ggaaagtttg
    25381 gtcaaggagg gtacaaaact tctggtggac tgcacggtgt aggagccagt gtggtaaatg
    25441 ccttatcgaa atggctaatt gtaacgatcg ttagagatgg cgtagagtat cagcagaaat
    25501 ttaaaaacgg cggtaaacct gacggtactt tgaaaaagat aggaaaaaca aaaaaagcaa
    25561 acgggacgac tgtccatttt ttaccagatg atacaatatt cagtacaacg aaattttcat
    25621 atgaaatttt agccgaacgg ttaagagaat ctgcctttct tctaaaaggc gttaaaatct
    25681 ctctttctga tcttcgtgga gaagaaccag tcaaggaaat ttttcattac gaagaaggaa
    25741 tcaaagaatt tgttgattat ctgaatgaag aaaaagatac attgacacca gttgtttatt
    25801 tttcaggaga aaaagaaggt atcgaagtag aggtcgctta tcaatacaat gacggttatt
    25861 cagaaaatgt tttatctttt gtcaataacg ttcggacaaa agatggggga acccatgaag
    25921 ctggtatgaa agcggcgatg acgaaatctt ataatgaata tgcgagaaaa gttggtttgc
    25981 tgaaagaacg ggacaagaat ctggaaggta gtgatttcag agaagggtta gctgctgtac
    26041 tttctatccg tgtacctgaa aatcttctgc aatttgaagg gcaaacaaaa gaaaaacttg
    26101 gtacgccagt tgctcgtacc gtagtagata acgtcatcag tgaacaaatg ggcttttatt
    26161 tgcaggaaaa tagcgaaatg agccagatgt tggtccgtaa agcaatcaaa gccagagaag
    26221 cgagagaagc agcacgtaaa gccagagaag aaagccgaaa tgggaagaag cgtaaaaaag
    26281 gcgaatctct tctttcagga aaattgacac ccgcacaatc ccgaaaccct aagaaaaatg
    26341 aattgtattt agtcgaaggg gattctgctg gcggatctgc taaacaagga agagacagaa
    26401 agttccaagc aattctacct ttacgaggaa aagtcatcaa taccgaaaaa gctaaaatgc
    26461 aagatatctt gaaaaatgaa gaaatcaata cgatgatcta tacgattggt gcaggagtcg
    26521 gtcctgagtt ttctatcgaa gactgtaatt acgacaaagt aatcatcatg accgatgcgg
    26581 atacagacgg cgcccatatt caagtattac tgcttacttt cttttatcgt tatatgaaac
    26641 cgctgattga agctgggaaa gtatatatcg cgttaccgcc tttatataaa gtatccaaag
    26701 gacaaggaaa gaagcaagtc attgaatatg cgtggacaga tgacgaattg gcagcaatga
    26761 ttaaaaaagt cggcaaagga tatatgctgc agcgatataa aggacttgga gagatgaatg
    26821 cggaacaatt gtgggaaaca acgatggatc cgacttcccg tacgttgatc cgcgtccgta
    26881 tcgatgatgc tgcgcaagct gaacgtcgag taaccacact gatgggtgac aaagtagaac
    26941 ctcgaagaaa atggatcgaa aatcacgtgc aatttacgct cgaagaagat ggcagtatct
    27001 tagataaaaa agaggatact gaaatctctc cttcagtttc taatgattta ttagatgaag
    27061 aacgagcaga taaaaatgaa aacaatcagt tatttgaagt agaataggag gtcacctgat
    27121 ggaaaatcga caagaagtac aagaattaac tttagaagaa gtgatgggtg accgcttcgg
    27181 acgttattcc aaatatatta tccaagaacg tgcactgcct gatatccgtg atggattgaa
    27241 gccagtgcaa cgccggatat tatttgccat gaacaaagat ggcaatacgt atgacaaagg
    27301 attccgtaaa tcagcaaaat ctgtcggaaa tatcatgggg aattatcacc ctcatggtga
    27361 ccgcagtatt tatgaagcga tggtccgcat gagccaagac tggaagttgc gggaagtact
    27421 gatcgaaatg cacgggaata acgggagtat ggacggtgat ccacctgctg cgatgcgtta
    27481 tactgaagcc agattatcca agttaagtgg agagatgcta gcagatatcg agaaagaaac
    27541 agtcgatctc gtgtggaatt ttgatgatac agaaaaagaa ccaacagtcc ttccagctcg
    27601 atacccaaac cttctcgtca atggatcgac aggtatatct gctggatatg caacagaaat
    27661 cccgactcat aacttagctg aagtgatcga tggcacaatc tatatgatcg atcatccaca
    27721 agcgagcctt gaaaaattga tggaatatat tcctggacct gactttccaa caggagggat
    27781 cttgcaagga aaagatgaaa tcaaaaaagc ttatgaaaca ggacgaggaa aagttattct
    27841 tcgttcgaaa acaaagatag aggcaatgaa gggtaataaa cagcaaatcg tgatcacaga
    27901 aatcccatat gaagtaaata aagcgacctt ggtgaaaaaa atggatgaga tccgtttgaa
    27961 taagaaaatc gatggaatag ctgaagtacg agatgaaagt gatagaacag gtctgcaaat
    28021 tgtcgtcgaa ttgaaaaaag acgccaatgc tcaaggaatt ttgaattatt tgttcaaaaa
    28081 cactgagcta cagatcaatt acaatttcaa tatggtcgct atcgaccata tgactccgca
    28141 tcaagttgga ctgaaagaca ttttaagaag ttatatcgag catcgaaagc aagtcataac
    28201 aaaacgtagt caattcgatt tagccaaagc tcaaaaaaga cagcatatcg tagaaggatt
    28261 gatgaaagct ttatcgattc tggatgaagt aatcgcaacg attcgtgaaa gtaaagacaa
    28321 aaaagacgcc aaaaagaatt tagtcgacgt ctttcaattt acagaagaac aagcagaagc
    28381 aattgtcaca ttgcaattat accgtttgac gaacacggat atcacagagc ttcaaaagga
    28441 atccgaaagc ttgattgcgc aaatcacaga gttgaataaa atcctttcaa atgacaaaga
    28501 gcttttctct gttatgaaaa aagaattgcg agaagtgaaa aaaaattatt cttccgctcg
    28561 tctaacgaca atcgaagacg aaatcgaaga aatcaaaatt gatacgcaag tcttagtggc
    28621 acaagaagac gtaattgtca gtgtgacgcg agaaggctat gtgaagcgaa caagccttcg
    28681 ttcttatagt gcttccaaac cagaagaaat cgggatgcga gaaggcgact acttgctata
    28741 ctcaggtgaa ttgagtacat tggaccatgt tcttctgatc acaaataaag caaatgtgat
    28801 ctaccgccct gtccatgaac tacccgattt gaaatggaaa gatgctggtg agcacatttc
    28861 tcaaacaatc tccaatctgt ctgtagacga atcgatttta gctgttttcc catatcaaaa
    28921 aattcaagca gagaaaacat ttgtattcat cagcaagaat ggattgatca agcaaacacg
    28981 aatgacagag ttcgaaccat ggcgcaccta taagagccgt ccgctcagct gtatgaagct
    29041 aaaggcggaa gaagatgaac tgattgctgt gtatctgaaa gaagatcagc caggcttaga
    29101 tgttttctta gtaacgcatc aaggaatggg tttgcgctat cctttaacag atgttcccgt
    29161 tgttggagca aaggcagctg gagtgaagtc tatgaatttg aaagatggag ataggattat
    29221 caacgggctg cttgtgttag cagaaggtga tacgccgatc gtaatcgtta ctcagcgagg
    29281 agctgttaaa cgcatgcttg ctcaagaaat cagccaaact tcacgtgcga agcggggagt
    29341 gacggtcatg cgtgagctga aaaaaaatcc gcaccgtatt atctatatgt cggaaggaag
    29401 atcaaaagaa ataaccttga tgaatcaaaa agggcagcag ttaacgattg acccaactga
    29461 tttccctata ggtgatcgaa catcgaatgg atcatttgcg atggatgaga aaaaaggtgg
    29521 agaagtcatc gaagttatcg atgctcctga gattttcatc gagtcgtaac tgttgtagta
    29581 ttttaatgaa gagacgccat ctgtattaat acaggtggcg tctctttttc attcattttt
    29641 aataaatcct tatacgtttg caaaaaaaga tgaaagtgtt cacaatgctt aaatgttggt
    29701 atgtcaacgt tgatttaaat atatgtaaat aaaacataaa aattgttaaa taaaaaacaa
    29761 gaaaaccctt gcaaagatag ggtgctgtgt tatactaatc acgtaaaaac tgttacataa
    29821 aacagaaatt taggaggtcc atacaatgga gcaatggaat ggatttaaag gtaccaaatg
    29881 gaaagaaggc gtagacacta gagactttat tcaaaataac tacactgaat atcgcggtga
    29941 tgacagcttt ttggaaggcc caacagaagc aacagaaaaa ttatgggatg aattgcaaaa
    30001 gttaaatgat atccaattcg agcgtaacgg tgtctatgat atggacacag aaatcgtatc
    30061 aactattact tcacacgatg caggctattt ggataaagat ttggaaaaaa tcgtcggtct
    30121 acagacagac aaacctttga aacaagcatt catgccgttc ggcggaatca atatggctaa
    30181 caatgcgcta aaaagcaatg gctatacacc aaacgatgaa ttgacacata ttttcactga
    30241 ctggcgcaaa acacataatc aaggtgtatt tgacgcttat actgctgaaa tgcgtgctgc
    30301 tcgtaaaaac aaaatcatta cagggcttcc agacgcttac ggtcgcggac gtatcatcgg
    30361 tgactatcgt cgtgtggcat tgtatggaat cgactatttg atggaacaaa agaaaaaaga
    30421 tcatgatatg actggttatc atacaatgag tgaagaagtg attcgtttac gtgaagaaat
    30481 cactgaacaa tatcgtgcat tagcgcaaat gaaagaaatg gctgcgaaat atggctatga
    30541 tatttctaaa ccagctgcaa atgcaaaaga agctgtccaa tggctatact tcggatattt
    30601 agcagcaatc aaatcacaaa atggtgctgc gatgtcaatc ggacgtatct cagcattcct
    30661 tgatatctat atccaacgtg atttggataa tggagtaatc acagaaaaag aagcacaaga
    30721 attgatcgac cacttagtaa tgaaattacg tatggtcaaa ttcgcgcgta cacctgaata
    30781 taaccaatta ttctcaggat tccctatctg ggctacttta tccattgcag gtatgggatt
    30841 agatggtcgt tcattagtta caaagaatga tttccgtctg cttcatacat taacaaatat
    30901 gggaccttca ccagaaccaa acttgactgt tttgtattct gaacaccttc cagaaggatt
    30961 cagaacatat gctagcagaa tcgctatcga aagttcttcg attcaattcg aaaatgataa
    31021 tcagcttcgt gaacaatggg gttctgatga ttgtgcgatt gcttgctgtg tatcaggaac
    31081 agttgtcgga aaagacatgc aattctttgg cgctcgtgct aacttggcta aaacactatt
    31141 atatgccatc aatggcggag tcgatgaagt gactggcgcc caagttggac cagaatatcg
    31201 tccaatcaca tcagaaatac tagactttga agaagtgaaa cataacttca tgaatatgat
    31261 ggattggtta gcagaactat atgtcaatac gttgaacatc attcattata tgcatgataa
    31321 atattcttat gaagcagctc agctggcttt gatggattct gacttgcaac gcacatttgc
    31381 tacaggtatt gctgggatct ctcatgcggc agacagcttg tcagcgatca aatatgcaaa
    31441 agtaaaagca atccgtaatg aaaaaggaat agcagttgat tttgaagtgg atggcgactt
    31501 ccctaaatac ggaaatgatg atgaccgtgc agatgaatta gtttcatgga tcttggaata
    31561 cttcatggga caaatcaaac gtcataaaac ttaccgcaac tcaaaaccaa caacttcatt
    31621 attgacgatt acttcaaatg ttgtttacgg taaaaataca ggaaatactc ctgatggccg
    31681 tgaagctgga aaaccacttg cgccaggagc aaatccaagt tacaatgcgg aacaaagtgg
    31741 gttattagct agcctgaact caacagctaa aatgaattac ggctgtgcat tggatggaat
    31801 ttcaaatacc caaacaatca atccttcagg tcttggaaaa gaacaagata caagaatcga
    31861 aaacttgcgt aatgtcttag atggatactt ctcaaaagga gcttatcatt tgaatgtcaa
    31921 tgtattcagt aatgatttat tgcgtgatgc aatggaaaat ccaatgaaat atccgaactt
    31981 gacgatccgg gtatctggtt atgcagttaa attccgtgac ttgacaagag aacaacaatt
    32041 agatgtcttg atgagaactt cacacgacag aatgtaaaaa gttcgtgaaa aaagtttttc
    32101 gacttagcgt cgaaaggacg ttgaatagcc atcgcatcaa aatcgaataa tcagtatgct
    32161 tatttgaaag aaacgattta caggggcagg acttgtatgt tccgtccctg taaattttac
    32221 acataacgaa gcggcaattg cgaaaaattt tgttcagaaa gcttcgcttc gacagctaac
    32281 ttgtacttaa aatgaaatca aagaaaagat gtgaacttaa atggaagaaa aaacaatcgg
    32341 ctatgttcat tctatcgaaa ctttcggttc agtagacgga cctggactgc gctttgtcgt
    32401 gtttatgcaa ggatgccgca tgcgttgcca attttgtcac aatccagata cttggaatat
    32461 tggcggaggg aaagaataca cagcagatga acttttagat aaagcagaac gcttcagacc
    32521 ttactgggga gataaaggtg gtattactgt tagtggtgga gaacctctat tgcagatcga
    32581 ttttttgatc gaactattta aaaaagcaaa agagcggaag atgcatacta cattggatac
    32641 atgcggaaaa ccttttacgt atgaagaacc tttcttttca cgttttcaag aattgatgaa
    32701 gtatacagat ttactgttat ttgacatcaa acacatcgat aatgaagagc ataaaaaact
    32761 aacgcattgg gacaatgaaa atattttaga aatggctcaa tatttgtcaa aaatcaacaa
    32821 accggtttgg attcgccatg tactagttcc tgagcgaagt gattatgatg aatatttgat
    32881 ccgactagac aactttattc aaaccttgtc aaatgtagac agagtagaga ttcttcctta
    32941 tcatacgatg ggaaaataca agtgggaaac acttggtttg aaatatccat tagaagggat
    33001 cgaaccacct acaaaagaac gtgtcgaaaa tgctaaacga ttgcttcata cagaagagta
    33061 tacaaaatat ttaacgcgat aggtcgcatc ggaaagaaga taagtattgc ttctttccgt
    33121 ttttttgcta ttattaaata ggagaaatca caaaggagcg aatgacatgt caaaaatttt
    33181 agtttttggt caccaaaatc cagatacaga tgcaatcggg gcagccattg cgttttcaca
    33241 cttgcaaaat gaattaggta aagaaacaga agcagttgct ctaggtacac ctaatgaaga
    33301 aacacaatac gcattagacc actttcagct atctgcacca cgagtagtag agtcagctaa
    33361 agcagaaaat gcagatgtca tgcttgtgga tcataatgaa ttccaacaaa gtatttcaga
    33421 tatcagcgaa gtaaatattt tagctgtagt agaccaccat cgtattgcaa actttgaaac
    33481 agctaatcca ttgtactatc gtgcagaacc agttggatgt acaagtacga ttattttaaa
    33541 actatataaa gaaaaccaag taacaattcc taaagaaatc gcaggaatca tgctctcagc
    33601 tatcatttca gatacattgt tgttcaaatc accaacatgt acgcctgaag atgaagcagc
    33661 tgcaaaagaa cttgcagcaa tcgctgaagt cgatctaaac acttatggac ttgaaatgtt
    33721 gaaagcagga acaaatctaa gtgataaatc agctgcggtt cttcttgatt tggatgcaaa
    33781 aagtttccca atgggcagtt ccaacgttcg tatcgctcaa gtcaatacag tggaccttaa
    33841 tgaagtgatg gatcgacaag cagagctaga agcagcaatg gaagatgaaa tgaaagcaaa
    33901 tggctacgat ctgttcgtat tagttgtcac aaacatctta gacagtgatt cagaattact
    33961 tgttgctggt aaaggaaaag aaaaagtaga agaagctttc caaacaactt tgaccaacaa
    34021 ccgtgctttg cttaaaggtg tcgtttcacg taaaaaacaa gtcgtacctc aattgacggc
    34081 tgtatttagc taatcaaatg gtagtatgaa gcattcaaaa tgaatggata agcgattgat
    34141 ataaaaagaa acatagaaca tactaaaggc cgaagaaatg gaggagaata acagtcaatt
    34201 atgactcttg ttcttcctcc tttttacgta aaagcctttt aagtaaaata aaacggatag
    34261 aaaagagaac atatatgaac tattattcaa aaaataagga aaacttttat caaaaactga
    34321 ccgatgatcc gcttttttct tcattgaccg attatctata tgaacatcga gaacaagaaa
    34381 cgattctaag agaattgaaa aaagaatttt cgcaaaataa attttcccat tttcttgatt
    34441 tattgatcga tgcaggatta atcaagaggg aagaacgaag atatcatttg aactttccaa
    34501 tatttgatcc taaagattac ttgcaacaag ccacttcggc tgctgaaacc atagctgaac
    34561 aattgaagag actctctgtt gatgaacaaa aattagcgat gggagaagtt atttgggcgt
    34621 attgtttcga agatgaacgg aaagaagcgt atttttatgg agtaagaaac agccgagaga
    34681 cagaattgct gaggacaact gcaggaaatg agaagtaccg ttttatcaca ctttcctcta
    34741 tagaacactt cccgcttact ttggctaatt acttttttgt acagaagaat cagcttcctg
    34801 taacgaaggc attcaaagaa ttagccgaac ttattggaga cgtaaatgaa tcgtactttt
    34861 ttgatcaaat agaagttatc gttgacagga tacgtaagaa taaatataaa aatcgccggc
    34921 ctagtatttt ccatcagtct ctacttgtga cgaatactat aaaggaagaa gaatcattca
    34981 cattagaatt acctattgtc gaaaaaaaca attttgagat tgaattacca acattggatc
    35041 cttcattgac aatggaggaa atggcctttc ttaaacgaca aatcttttct gagctgagca
    35101 agaaatttat accgcatgca ttttcttata tcaaagaata tggaacagtt ttagtgagta
    35161 aaacctaaga gagcagtaag caaaaattat actgactctt gcaggaggag cctttctctt
    35221 cctttatggt taaaagaatt atttgagtat tttgcctatc taccacctat tagattcact
    35281 acatggtctg gaaacaaagg aatgcaaaaa aatggtgaga aatgtggaat gacaaaggaa
    35341 gtagtgataa gaaaagttag atttttaaat aatcaatatt atgattcagt caagtatggc
    35401 attttatggg aagaactagc tgattagatt aggaagtcca tttgataatc cagaatcact
    35461 aagaaacgaa tggcgagtca ttaataattt atccaatctt gggttattct tttagattga
    35521 agtgtttaaa actaaaaaag catttatgaa gtcgtaatag tcaggcttca aaatgctttt
    35581 tattttgttt gttttttctt tgccacataa atacacctag actgacgatg aagagcatat
    35641 ccaacagatt tcctgcgact tggatcgtcg aagggttggt cagtggcatt aaagcaagga
    35701 caaaaaagga aaacaagctg taaataaaac aggtgacagg aactaatcga aagaagagcg
    35761 gacatttcaa ttggctaaaa atgagtgaaa aaataaaata agtaaaaatg gataaaatca
    35821 cgactaaacc attcatgata aagaagaaaa gcgtattgtg attaaacgaa taaaaaagaa
    35881 ttgctaaaaa agaaaacgtt ttaaatgcaa tcaatacgct tgaagcttcg tttaacgtac
    35941 caggatgtcg atgaaaaaaa taggcaccga aataaacaga aaacagtaag ccgcaaagag
    36001 aagacaaaat caaaaaaaac ggattttctt cggcttctgt gatatcagaa tgatccaaaa
    36061 gcaaccagcc taatgcacta gaaggcgcat gtgaggtctt aaggtatgaa taacatagaa
    36121 aaaataagat cgtcaaagtt gcaaaaaaag agcctaaatg taaaaaatta gtggttctac
    36181 gttgaatttc cataatatct ccaaattaaa ttgataagta tataaagtat aataacaaat
    36241 tgatgagtat atgtcgatgt tttttaatca aaataataaa taaaaactgt ctaacattta
    36301 aaatttaatt tagatattag acagttttta agtttgtgag ttattttcct tgtcgttttc
    36361 tcactttttt agtccagaaa ccacctgaaa tatattttgg ctcataagaa atgataaaag
    36421 cacgctcttc gatttctttg atcaggcgat acagttcacg ttcgcttttt ctaggagaaa
    36481 gtatttcgag aactagccgc tcaccttcca gccccattgc agaagtctgt gtcacaccat
    36541 aaccgtgttc tctcagtata cccggcaaac ttttatcttc tgcgctattt gctggcaaaa
    36601 tcgttgtgac catgatgtat cctaatgcca atttgtcttc aatcaaaatt ccgacactga
    36661 tacctactgc gtaacctaac gcatagacaa ataaattcag tggattatct aaacgatcta
    36721 aaacaaggga taagccgacg atataaatcg tgatctcgac catactgaca agtggagcaa
    36781 tcagtcgata gcctttcatt gtcaacatga aacgtaacgt gttcagagtg atataagcaa
    36841 aattaatgag gaagatcatc cccaacattt ttggatcaat catttgtaaa actcctttca
    36901 tttatataac aacaatatca aaaaaaatcg taagtgaaga aaaattgaaa ctttatacat
    36961 acaaaaaaat gataaaatga ttataataga attataaaga taggttaggt gattaaaatg
    37021 aaaacggtca atcgtgtgtt ttgtgccagc cacgtgctaa gtctccttct cagtatatac
    37081 ttaggtgtct attcgattca acagccaatt gaggtagaga acattgtttt tcagatgtcg
    37141 ctgacagatg gtttaatttt aagcgttttt ttctttttga tactgtttat tggtaatatt
    37201 ttcggtagcg ttgccagttt tttgaatttt tctatttatc cactcctttc gctagcatta
    37261 ggagtggtgg gactttgttc tctgtgctta tttcccgagc cattcagtcc tgcatttata
    37321 ttatttggta cactgaacct gttccagaca actgttggag catggttgct atggcgatca
    37381 ggaaatttaa tgaaaatagg tgagtaacaa ttgaatccaa ttatattgaa acgttctgtc
    37441 catcatattc cagtgttaga agttgttctg aaagaattaa gagaggaacg tattcccgtt
    37501 gtcatctatt atcacggatg gcagacaagt aaggagttag ttttgacgca aggaagaaaa
    37561 attgcgcagc agggcattcg tgtgatcctg ccagatgcga tgaatcatgg ggagcgcaaa
    37621 cagccggttt cttctattcc atcctataca ttttgggata gtatctacgg aaatctgttt
    37681 gaatttgaca cacttatcaa gcatttagaa aaaagaggtc ttctacatga tcagcttgca
    37741 gttggcgggg tttcgatggg gggaatgaca acatgcgcct tgttggctaa acatcctcat
    37801 atagtagcgg gcgtgtgttt gatgggttcc cctgcacctt tggaatatgg aaaagaaatc
    37861 gtaaggcgcg catcggaata taattatgtc gtaccaaaag actattttga tttgatttca
    37921 tgggttaaga gctatgattt gtcattgcag ccggaaaagt tagctggacg tcctctgttc
    37981 ttttggcatg gacaagctga cgaaaaaatc ccttatatac aaacggaacg atttgtagaa
    38041 aaaaatcggc ataagtctta cggaaaagaa attgtttttc gttcctcaaa aacacagcga
    38101 catatggtac aaataccact aatggaagaa gcttccactt ttttagcaaa aaatttgata
    38161 aaaaagtata aataattgaa acggaaaatc actcatgacg atagaggatt ttccgttttt
    38221 tattttgggc tataataaac tctgttagga aaatttggta taattgatag taagaatgac
    38281 aacatgttag aaaggaagag agcatgccca ctttagcaga tgttgcaaaa cgtgccaatg
    38341 tttcaaaaat gacggtctct cgagtcatca atcatccgga acaggtgact gacgaattga
    38401 aagagttagt tttctcagca atggctgaac tggattaccg tccaaatatt gctgcaaaag
    38461 cacttgtcac gaatcggtcg cagatcatca aattatttat actggaagaa atcgacacaa
    38521 ctgagcccta ttacatgaat ttgctgatgg gaatcgctaa acggatcggt aaagcgcatt
    38581 attctctcca attagttaca aatgatgcct tcgacgtcgg ttcttgtgat ggatacatca
    38641 tcacaggtgt cagaaaaaaa gacttcgatt ggatcgaccg tttggaaaaa ccagttgtct
    38701 tgtttgggga aaattctgaa ggatatgatt atgtagacag cgataatgaa tatggtacag
    38761 caaaagcaac gcaatatgcc ttagaaagag attatcaaac gattatttat atcggtatcg
    38821 aagtggacga gccttttgaa atttcaaggg aaactggtta tttatctgtg atgaaggaag
    38881 ttgatcttcc tagtaaaatc ttgcggtttc caaatcattc gacagaagta gaaagatata
    38941 tgacagaaaa ctgggcagat tttacagata aaacttgttt tgtatgtagt tcagatcggc
    39001 tagcactagg agcagtaaga gggattataa atgctggagg acacttgccc gaagaatttg
    39061 gtgtgattgg atttgatggg gtatttttag accaaatcag ttcacctaaa ttgacaacga
    39121 tcaagcaaga tattatacgt atgggtgaag tatgtggaga aatgttgtta aaaaaaatag
    39181 aagaaaaagg ggcgagtcaa ggttatcgtc gtttttttcc tgaactagtt atcagagaga
    39241 caacgaatta agtcttatta ctatatatat atttatgaaa ttcatcgcta ttttcttaaa
    39301 ataatcagcg cattgctact gaaaacaatg aatctgtgct attattgaga aaagttccat
    39361 ttttgagaag gatggtttga atgaaagaaa tcagacgaaa acatttccgt tttcctgcgt
    39421 acgatgatga gttaggcgta aaattaacca acgacaagaa gcgagtatta tttgacggac
    39481 aagaagatct tttgactgaa cagaatcagt ccccgtttga acagatgaaa gaatttcatt
    39541 tcacgaacac gaacaccgag aaaatccgtc gcaagcgtcg tgcaacaaat ggattgaagt
    39601 cagctccgcg taaggaaaat ttggaaaagc ataaaggaaa attaccggat tataccggcc
    39661 attaccaatc agaaatcaca tcgacaggac gaaaaaaact ttttggtgat tcctctcgtt
    39721 ctgtcagaca aagtgaaaca aggacagagt ccaagcatac tacacgaaac gcatctgttg
    39781 acacgaaggt gcgggagcgt tcttattttg ttcctaaata tgtacccgca tcgattatcc
    39841 cagaccctag agaaagcaaa atttctgagg atcatttaat cgaatcgatg aaaaaaacgg
    39901 atgactctta tctgttgttc gatacagaac cgacgccgta tcaagaaaaa agaaatggtg
    39961 agccgtctgt acgaacattc aatcgaacaa aaacgttaga ggaaacaaag cagtcagaag
    40021 aaaaaaaatc gaaaaaaagc catggtatct tagaacgctc attacaagga ttgatcgatg
    40081 atcaaggaaa ctctttggga gaaaatagct attttaaata agtgatatac aaatttatat
    40141 tcggctacag ttggaaagga aacgctgcgg cgtttcctta ttttatactc tatccgaaag
    40201 tttatatcgt atcctcaaat ttttttgagt ttaagcgaat tttttctccc aataagtaag
    40261 aaaataatgg caaaataaaa aaacaaacta ttttcgcaga tcgtttgcaa aaatagttta
    40321 tttttttata aagaagattt tactgaataa tatcatttta gtttacataa tgatatttct
    40381 gtaaattaaa taaagtagtg aaaaataaga atcagtgctc taactgttca agaggatcaa
    40441 gtggttcaaa tgtttctgta gtctgttttg cttccaattg gggcaaaaca gatccaattt
    40501 ccagatactt cactttattc aatgtataag atagaataga acagctaagt aatgtataca
    40561 gaaaatgtgt gagatccaaa taaagcaagg agacaactaa aataccaaaa gtaatcaaga
    40621 aaagactttt gccaatctta atatgaaaat atttttcaat ggcttgataa atgatatctg
    40681 ttccgcctgt gcttccgccg aatcgaaaga cgagaccgca accaatgcca gaaagaatac
    40741 ctgtcatcaa actattgatc agtagactat ctacagcaaa atgtatatga aggctctccc
    40801 ataaatgtaa aaagaaaact agcgcaaatg ttccgacgat cgtccggaga aaagcgtgtt
    40861 ttccaaaaag aaacaatgag ataagcaata aaggtaaatt aaaaagcagt gaagtgacag
    40921 aaggagcgaa tccaaaaaga ttatgcaaaa gcaaagcaat accagtaacc ccaccatctg
    40981 ccagcttaga tggaatattg attcctgtca cagctaatcc gtagattcct gcgcctaaaa
    41041 tgattccgca caattctgta aataaattta attttttcat ttctagcctc ttttcttttg
    41101 aaaattttca gcaacttctt tattatactg acttatactc ttacttcaag aggaaaatga
    41161 aaaaaaatta tttttggctg tttcttttta tttatcaaat aaggagtgga aaaatgcgag
    41221 cagcagactt attgacaatt cttacaaaat cacccaaaaa aacagagtat caaggagttt
    41281 ttttggctca agaacaaaaa ctggtgcctg tgacaatggt ccagataaat aaagcaaatc
    41341 aatttatctt tttatttgaa cacggcaaag caccacttgc tatgaaagac atctttcttt
    41401 ttttgatgaa gaaccgtgag aaagctgttt attatcagtc aaaagaagaa ctcattcctc
    41461 tttatggagt gaaagagata gaaaataaag tggtgatata agtaaaaata agaaaacaag
    41521 acgtttatga tgtcaaaaca accatttttt acatttttgg caaaaaagtg tcatgataca
    41581 gtataatatt cgttgaacag gccaataaag gtgttctccc ccacgagatt tctactttat
    41641 tggctgtttc tttttattaa aataaaagtt gtgtgtgtaa aaaagatata gctgattcca
    41701 agtgacaatt tcgtatagat ttttatggta ttcgtagtga aaaaacgaga accaaaaagt
    41761 tgatccgact ttgttgcttg gattcttttt ttgtcagcat atttagaggt atttttttct
    41821 tttttttgtt cgtgctgtaa ggttaaggca agacaagtta gttgggaaaa aggaaagaaa
    41881 tgtttatact taaagaataa cagaaaggaa ggtcgcatga ataattttat acaaacatta
    41941 agtgaaagaa aaggcgagtt gctggaagct gcatttcaac atctgtccat ttctctcatt
    42001 tctttgctga ttgcagcact gattgctatt cctttagcga tttgggcagc caatcataaa
    42061 aaaatggcag aagtcttatt gcagatcacg ggtgtgctcc aaacgattcc ttcacttgcc
    42121 ttattaggtt tacttatccc atttgtaggg atcggaactg ttccagcatt gattgcactt
    42181 gttatttacg ctttgcttcc gattttccaa aacacgtata ttggtctagc tgaaattgac
    42241 ccgtctattg aagaagcagc ggtagcattt ggtatgtcca gaatgagacg cttgctgaaa
    42301 gtagagcttc ccatcgcatt acctgtcatt atctcaggta tccgaactgc cttagtttta
    42361 atcatcggta cggctacttt ggcagcattg atcggagcag gtggattagg gacatttatt
    42421 ttgttaggta ttgaccgaaa tacacctgtt ttgacattga ttggtgcgat cagttctgcc
    42481 ttgcttgcaa ttatattcag cggactgatt cgctggttgc agcataagaa acctcgatat
    42541 tccatcatta ctttagcagc agtggtgtgt ttatttggcg gcgtttcttt atatcagtct
    42601 gccttgttta aaaatgaaac catcacgatt gctggaaaat taggagcgga acctgaaatc
    42661 ctgatccaaa tgtataaaga attgattgaa gacaacacaa aaacagaagt tgaattaaaa
    42721 ccgaattttg gcaagacgag ttttttgttc aatgcactgg atcaaggtca aatcgatatc
    42781 tatcctgagt tcacaggtac tgtcctagaa agcttggtga aggtacctga agcaatgaaa
    42841 agtgctgatt tgacaaaaga aaaaacatat gacgaagcag aagaattatt gaataagcaa
    42901 ttcgatatga cattattaaa accaatggct taccaaaata cgtatgcctt ggcagtcaag
    42961 agatcttttg cgaacgaaca tcaacttaaa aagatttccg atttggcagc tatctctgat
    43021 cagatcaaag cgggattcac actggaattt attgatcgtt cagatggata taaaggaatc
    43081 caagaagcat atggcttgaa tttttcaagt gtacaaagca tggagccaag tttgcgttac
    43141 caagcaatca ataatggaga tgtcaatatt gtggatgcct attccacaga tagccagctc
    43201 aaggagtacg atctagtgac tctagaagat gatcgagggt tattcccagc ttatcaaggc
    43261 gcaccgctga tgaaaaaaga ttttgctaaa gaacatcctg aaatcgttaa agcactgaat
    43321 aaattaagcg gaaaaataac agaggatcaa atgattgata tgaattacca agtcaatgtc
    43381 gaaaagaaaa agccgacaga agtagcacga atcttcctga aaaatgaagg attagtaaag
    43441 gaggaagatc agtgactaaa ttaatcgagt tcaaacatgt gcaaaaaaag tatgatggaa
    43501 agtatgtcat cgatgaccta aatctggcaa tcaaaaaagg agaaatcttt gttttggttg
    43561 gtccttccgg tagtggaaaa acaactactt tgaaaatgat caatggatta tctaaaccat
    43621 cagcaggaga catctacttc aaaggaaaat cgttaaatga atataatctg cagaaaatgc
    43681 ggtggaatat gggatatgtg ctgcagcaaa tcgctttgtt cccgaccatg acagtcaagc
    43741 aaaatattga agtcatccct gaaatgttag gttgggaaaa gcagaaaaga gcagaccgtg
    43801 tagatgaact tcttcaaaaa gttggcttat ctcctgatat ttatcgagat cgtatgccta
    43861 gagagttgtc tggaggagaa cagcaacgga tcgggatcat ccgagctatt gctgcaagcc
    43921 cagatgtgat tttgatggac gagccattta gcgcattaga tccgatttca agaaactcat
    43981 tacaagaatt ggttttgtcc ttacacgaag aattgggcac gaccatcgtt ttcgttacgc
    44041 acaatatgga agaagcaatc aagctaggtg atcgtattgc atttatgaag gatggagaaa
    44101 ttatccaatg tgacacacca gagcagttat tgatgaatcc taaaaacgac tacgttcggc
    44161 atttctttga tgaaccgaaa cagacgaaag agtggcgagt agaagattta gtcgtcaatg
    44221 gatatttctt aaatgaaata ccagaaaatg ctcgtcaaca agtttgcttt gatacgccta
    44281 tgaaagaagt atattcgctt ctttcggtgt atccaagcat tgtgatagta gaaaagcaaa
    44341 gaagtattgg gtcgctgaca agtaaagaaa tctttgcttt tttaagtcga gaggaggaag
    44401 gaaatgaaaa catatgatgc aatcatcatc ggttcaggtg tgagcggctt aagtgctgct
    44461 tatggattga aagaagcagg taaaacagta ctagtggtcg aagaagatct atggggcggg
    44521 acttgtccta accgtggatg tgatcctaaa aaagtcttgt taagtgcagt agaggcacgt
    44581 aatcgggtaa aacaattgag tggaaaaggt tttaacgaga tcccaactgc caactgggaa
    44641 gaacttcaaa aattcaaacg aacatttacg gatccagtcc cagaaagccg aaaaaaacaa
    44701 ttagcagaag ctgaaatcga tcatctttca ggaaccgctc gttttttgga tgattcatct
    44761 attgaagtca acgaagaagt cttccatgcg gattacttag ttttggcaac cgggcaaaga
    44821 cctacgatct taccagtgga gggaaaggaa tacttgaaaa ctagtgcaga ctttttatca
    44881 ttgcctgtac tgcctaaaga aatcattttt atcggtggtg gttatattgc ttttgagcta
    44941 gctacgattg ccaatgctgc agggagcaaa gtaaccattg tccatcataa tcaacggcca
    45001 ttaaaagaat ttgaggcgtc tttggtagag gaagccgtcc atcaaatgga agcatctggc
    45061 attcagtttg cttttggtgt tgaaacccaa aagatcattt cagaaggtac tcgctatcgt
    45121 ttagtcggaa aagagacgga attagtagca gatatgattt tttgtgcgac tgggagacag
    45181 ccgaatacag aatctttagc acttgagcaa gcgaatatcg tctttgataa acacggaatt
    45241 gcagtcaatg attatctgca aacgagcaat ccaaaaattt ttgcgtgtgg agatattgtt
    45301 tcaaggaaaa ccccaaaatt gacaccagtc gccacttttg aaggaaatta tgtagctaag
    45361 cggataacgg atgcaacaag cgaacctatc aaatatccga ttatacctac gatcgtctac
    45421 gccagtccta aacttgctga agtaggagtt acaaaaagtc acgcctcttc gtcagatcaa
    45481 gtggtagaga tggatcttac cagttggttc acctatcatc gtgtcaatga accagttgct
    45541 aaggctgaat tgacctttga ccagcaaaat tatttgattg gtgctgcagt gattagcgag
    45601 caagcagacg aattgatcga tgatttgaca ctcgtcatca atcaaaaatt gactaaaaaa
    45661 gagttggata gctatatcat ggggtatccg acattggcaa gtgatctctc ctatttattg
    45721 aaataatcag catgataact aaagcgcttg ttgctttttc cttcttgtgc tacactttaa
    45781 aaaatgaata cctgtttctg gggatgtcgt agacgacatg agagtaagtt gtgaacttag
    45841 acccattgaa cctgtcagtt aatactggtg aagggagaaa catagcagac gcttgaagcg
    45901 ggttactatg tcgtgcccat ttcaagcgtt ttttgttatt catattagaa gaaaggaggt
    45961 aacaaaatga agaaaaatct ttatccagca gtcagtatgg cattcatttt aattatttgg
    46021 cagattgttg tcatagtttg gaaaatacct gcctttattt tacccggacc tgctgctgta
    46081 ttttctgcat tagcggcaga tgcacaagta ttactttccc attctgtcac gacattaaat
    46141 gaagcagtgc ttggtttggt aatagctagc gttctttctt ttattactgc cttggcaatg
    46201 gattattgga agtttttaga aatgtctttt tatccgttac tagtgatttc acaaatgttg
    46261 ccaatcatgg tgttagggcc attacttacc ctatggtttg gtttcggtat gcttccaaaa
    46321 gtgatccttg ttgtcttgat aagctatttt ccgatcgtag tttctttttc ggatacattg
    46381 aggaaagtat caaaagagca aatcatcttt ttgaaaacga tgggggcaga tacagggaag
    46441 atttatcgaa tatataaaat accagcgggt ttatccggct tcttttccgg tttaaaagtg
    46501 gctgctactt attgtgtcag cggagcagtc gttggagaat ggctaagcgc tcaagcaggc
    46561 ttagggtatt acatgatacg cgtaaaaaac agctaccaga tcgataaagt ttttgctgcg
    46621 atcatttgtg tcattctatt gagtttattg ctgaatggcg cttgttcatt attgaaaaaa
    46681 gggtattatc gtatgcttta tattttttaa gagaagggga tcaaatgaaa aaattatggc
    46741 ttttattacc gctactgttg cttttatccg cttgtggcac tgcaaaagaa acaagtagca
    46801 aacaagaaat aaaggatttg aaaaaagtga cacttgtttt ggattatgta ccgaatacta
    46861 atcatactgg catctaccta gcaaaagaaa aaggctatta taaagaggct ggtttaaatg
    46921 tccaaatcat cgaaccagga gataattcga caagtattgg tctagtaggt gcggacaaag
    46981 cacaatttgg tgtaagttat caagaagatg tcacttatgc tcacgcagat ggacagaata
    47041 taccagtcaa agcaattgct acagtgatca aacataatac ttctggattc gccaccctat
    47101 cagacagtaa catccattca ccaaaagatt ttgaaggaaa aacatatgca ggttggcaaa
    47161 gtccaagtga agaagctgtc ttaaaagctg tgatggaaaa agacggcggg gacttttcaa
    47221 aactgacaat ggtaggaagc aatggagaag ggccagaaag cttaggaaaa tcctcagata
    47281 tccaatggta ctttgaaggt tgggatatga tcaaagcaaa agaagcgggt attgaactaa
    47341 actatatccc attgaaagaa ttagatgaac ggttagatta ctatactccg gtaattatta
    47401 cgaatgatca actgatcaaa agtgatccag aattggtaca gtcttttatg gatgccacga
    47461 aaaaaggcta tcaggaagct attaaggatc caaatgacag tgctaaactg ttgcaaaaat
    47521 atgcaaaaga aaatgatcgg acgtttttag aagaatcaca agcattcttg tcaaaaaatt
    47581 atacggatga tcctgagaat tggggattga tggaagaaaa agtttggcgc aattatacag
    47641 cttttatgca ggaaaacgga ttgatcaagc aagatgtacc ttcgcaagaa ctattcacta
    47701 atcagtttat aaaataggag tgatagatat gtcaatccaa atcagccact tgaatgtagt
    47761 cattgaaaac ctgaaaatat tagaagacat ccatttcact atccctaaag atacctttac
    47821 atcgattgtc gcgccaagcg gagccggtaa gtcaacattg ctgaaaactt taacaggagt
    47881 ccagcctatg acttctggaa cgatcaaagt agacgatcaa aaagtaactg gtctccatac
    47941 agcatttagt tatatgccgc aagaagatat gttacttcct tggctgagcg tctatcaaaa
    48001 cgttacgtta tatcaaaaaa tcaatcatct aacaatcaat gaagaacaag taagggatta
    48061 tctggatatc tttgggttaa acggctatga acattttttg ccggaacaat tatctggcgg
    48121 gatgaagcag cgaacggcct tgttacgaac aatcatgaat ccttcttctt acttgcttct
    48181 tgatgaacca tttggagcgt tagatgctat gaccagaggg cagatgcaag actggatgtt
    48241 gaagctgcct aaaaaagcaa agcggactac tttacttgtg acgcatgata tcgaagaagc
    48301 aatttattta tcagacagga ttcttgtgct ttccgcccgt ccggcacatg tgattgctga
    48361 gattcaagtg cctgaaaaac gacggtcacg tgaatggcta ctgcagcaat cagagttgaa
    48421 gcaaacgatt tatcagttat tggcaggtga attagatgtt aagtgatgct cattgtcatt
    48481 tagatgggag tcagagttta gcactccttc agcaggaaca cacgattttg acgatcatca
    48541 attgtgattc gccagaagaa tggaaggaaa acagacagct tgcagcaagt aagactcaag
    48601 ccttaagtta cggtatccat ccttggaaag cagatagcta tacgtttgaa caagttgagc
    48661 cttttttgaa aaaagcaagg atcatcggtg aaatagggtt agataatatt tggacgaatg
    48721 taccgatgac tacacaaaaa aaagtatttg agcgacagct tgcttttgca gccataaatg
    48781 agaaacctgt tgtactgcac acaaaaggat gcgaaaaaga gatcttaaat tatatccaag
    48841 cttaccctaa tcactatttg atccattggt attcttcttt ggactatcaa caagactata
    48901 ttgatttagg ctgttatttc agcattggtc ttgatttgaa aaagaatcca gcagtctggc
    48961 aactagctaa agcagtccca atcgaccact tacttattga aacggatgga ctacatgcag
    49021 cagagtgggc tttagggggg attttttcag aaaaagatta tgtctcactg cttgaagaac
    49081 agttaaagac aatcgctgag atcaaagagc tatcagttga agaagttaaa aaaaatactt
    49141 atcaaaactt ggaacgtttc attagattag gtaaataaaa aagagatgtg acacaactag
    49201 tgtcgcacct ctttttggct ttctttgtat aaaagtaaac tgtttgatta ataaatgaat
    49261 cttagtacca accgtttgct tcccagaatg ctttcgccgc ttcccaagaa ccataacgtg
    49321 aagtaacata ttgttctgct actctttctt ggtttgcagc agagtagtca ccatttaagt
    49381 aagaagaatc taattggtaa cgtccgatgt aacgtccgtt cgttgctgtg taagaaccgc
    49441 ttgattcttt ttgtgcgatc cattcttttg cagagcttgt gcttgctgga gtagcagcag
    49501 tttctgttac agcaggagca ggttgtgttt cagcaacagg cgctgcttgt ttttccgttt
    49561 gaaccgtttc ttgtacaaca ggttgttcag cttggactgg tgcttcttga acggctgctt
    49621 gaggttcagc agctgcttgt gcagagcctt ctgttgggat tgttaattgt tgtcctgagt
    49681 aaatcaggtt aatatcagaa attgaatttg attctgcaat ggcattgatc aaggagttat
    49741 caccaacgta tttttgagaa atcgttgata gagtatcacc tgattgaacg gtataagctt
    49801 cgtccgcatg agcagtcgtt cccatgaaga atgcagcgcc ggcagccaaa gttgttccaa
    49861 aaagtaaagt tttaagtgat gtcatgaaaa atctccttta ttcgttaaaa agttttattt
    49921 gttgtgttca acgaggaata ctttaacacg tgaaaatatt tcataggtaa aagaagcatg
    49981 acaatttatg acaaatccgc gttttttgta ataaatacag taatctatga aatgaaaagg
    50041 gttacgttta ataaaacttg cttttttgtt tttgttcacc ataaatattt atttaagaaa
    50101 gtattaacct gcatttttct ctataaaaaa gattttttaa atagataaaa aaggaggatt
    50161 aaatgagtat ttgatagtat ttatattaaa attacatatg taatttaaaa acgcttgaca
    50221 ttgtgtttga gatcacttac ttttagcatg taaaagtatt ggattaagga gctatgcaaa
    50281 tgaaaaagaa atttattact ggtgggattg tcgttgcatt tctatgtcta attggctaca
    50341 caggcacgcg gtacgcaaat gaaattattt tgtggggtgg agagacagat attgatacaa
    50401 tcaatgagaa tctgacacag cttgatcata cattgacaga taaagagcaa gcgattacag
    50461 atcttaccgc tcgactagca caaaaagaac agacattgca agattcaaag gcagatgtcc
    50521 aagaatacca aacaaaagta aatgaattag aaaaccaaaa aaatcaatcg gcagcagaaa
    50581 aacaaaactt agaaagtcaa ttagtcagca aggatgcaca actacaaagc aaacaaaatg
    50641 aaatcaatgt caaactagat gagatcaacc aaaaaaatga tgaaatcaat catctgaatg
    50701 cagattggac agcaagacta caagaagcac aagcaaaact ttcagaatta caaaatactg
    50761 taaatggttt gaatcaacaa atcgcaacac tgacacaaga aaaaacaaat gtagaaatca
    50821 gttaacagat acacaaaaga aattagacga agcaactgct gaaaactcaa gcttgaaaca
    50881 atatattcaa aagttagaaa aagcaaaaga tgaagtggaa gatacagctg ataaatctca
    50941 gcaaattgtt gaagaacatt tgcgtaaata atctttctta acaagtaaac ctaaattagt
    51001 aaagaagcaa cagtaatcta tactgctgcc tctttttttt agtacatgtc cttcatcttc
    51061 gcaggaagtg ccaatatgat tttaagaaag gtaatagaca aaaagtcaaa aagataaaac
    51121 agagtttctt ctttacaaag ggaatgtatg ttcgtataat ggtattgagg tgaaggttat
    51181 ggagaaaaaa tatggaacag tagataagat ccgtactttg caagttagtg ccagaccgtt
    51241 gatccgtttc agtttaaatg gggtcaattg tttgattgct tcccatagtt tgaacttcct
    51301 agctgaagta gacgaaggga tgaagttagt cgttacaggt tattataata atagaaagca
    51361 atttgttgtg agatcctatc atgtgttagg gaaacccaaa attgtggtag aatatgagaa
    51421 aagtctatac ccaagaaaaa aggtccgaca agatgaaaga ataaactaga aaacaagcgg
    51481 ctgagacaaa aatgtcctag ccgcttgttt tggaaagatg gatgcagacg atgggatttg
    51541 aacccacacg agcatacgct cacaagaacc tcaatctata tataactaca tgtatttaag
    51601 tatttgtgat gaatcactaa actttccaaa ctcatttgag ggatattgct taaagattga
    51661 acagatcaat tcgaagccct attagtattc gctcaatggg gggatcagag gccataaaaa
    51721 gagactagtc attactagtc tcaggtagtg gaattgtagg attttaaacg ttcctggaga
    51781 gtaccggtat gtaactcgaa gaggtgatta tcatagtcgt aaaagtaaat tgaagaagcc
    51841 tcgcctttca cacgagaacg tcctggttcg acagttaaac ctaacatttg gatttttgag
    51901 acaaacgaat ctatatcttg ttcgtcaatt ttaaaagcaa tatgattgta tgtctttggc
    51961 agtttattcg acgaattctg cattactgca atccataggt ccttaactaa gaaaaatttt
    52021 tctggatata atgaaaattt ttttgttgac tatcgtagat ttcttttgca tcaaataagg
    52081 tatttaacaa ttaagtattt aaaagataac ttttaagtta tctttaagta atgcttaaag
    52141 ctatgttata ctctattagg aaatataaga aggagtataa aaatgaacaa acataataga
    52201 aaaataacga ataacaaaga actgatcttg ttactaatag ggatttgggg tatcttttta
    52261 ctctttaata tgtatatgcc gactatgaga gcggatgacg tagtttatgc aagtagatta
    52321 gatgaacttg gctatttggg tgcttcgata gaacattata agacatggag ttcaagaatt
    52381 attatagaac tattcttaat gttcttttct aaacacttta tgctatggaa attattaaat
    52441 tctacgatta tgttaggaat tgtagtatta ctttgcaagt atgt
//
LOCUS       DAPBAF010000018        51058 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.018, whole genome shotgun sequence.
ACCESSION   DAPBAF010000018 DAPBAF010000000
VERSION     DAPBAF010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 51058)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51058)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51058
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.018"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            212..604
                     /locus_tag="RD451_001193"
     CDS             212..604
                     /locus_tag="RD451_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDT7566465.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
     gene            632..1972
                     /gene="glnA"
                     /locus_tag="RD451_001194"
     CDS             632..1972
                     /gene="glnA"
                     /locus_tag="RD451_001194"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HDT7566466.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            3165..4775
                     /locus_tag="RD451_001195"
     CDS             3165..4775
                     /locus_tag="RD451_001195"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HDT7566467.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            5067..5936
                     /locus_tag="RD451_001196"
     CDS             5067..5936
                     /locus_tag="RD451_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HDT7566468.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            6101..7372
                     /locus_tag="RD451_001197"
     CDS             6101..7372
                     /locus_tag="RD451_001197"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HDT7566469.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            7369..8664
                     /gene="rho"
                     /locus_tag="RD451_001198"
     CDS             7369..8664
                     /gene="rho"
                     /locus_tag="RD451_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HDT7566470.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            8763..9026
                     /locus_tag="RD451_001199"
     CDS             8763..9026
                     /locus_tag="RD451_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HDT7566471.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            9471..9920
                     /locus_tag="RD451_001200"
     CDS             9471..9920
                     /locus_tag="RD451_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDT7566472.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            9977..11395
                     /locus_tag="RD451_001201"
     CDS             9977..11395
                     /locus_tag="RD451_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDT7566473.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            11395..12255
                     /locus_tag="RD451_001202"
     CDS             11395..12255
                     /locus_tag="RD451_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HDT7566474.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            12429..13202
                     /locus_tag="RD451_001203"
     CDS             12429..13202
                     /locus_tag="RD451_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDT7566475.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            13349..13714
                     /locus_tag="RD451_001204"
     CDS             13349..13714
                     /locus_tag="RD451_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HDT7566476.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(13862..15070)
                     /locus_tag="RD451_001205"
     CDS             complement(13862..15070)
                     /locus_tag="RD451_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDT7566477.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(15089..15367)
                     /locus_tag="RD451_001206"
     CDS             complement(15089..15367)
                     /locus_tag="RD451_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566478.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            15521..16216
                     /locus_tag="RD451_001207"
     CDS             15521..16216
                     /locus_tag="RD451_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HDT7566479.1"
                     /translation="MIFLDESLDGGASLDSRVLKEYLDKNDFPIIRKGYHKYLTFEGM
                     EDSHTYILKEGTVKASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESE
                     YAEFYRINRVRFWQNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLY
                     ELYDLFGVRTEEGMLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIV
                     ILNMDLLEDNIIF"
     gene            complement(16658..17455)
                     /locus_tag="RD451_001208"
     CDS             complement(16658..17455)
                     /locus_tag="RD451_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HDT7566480.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(17452..18636)
                     /locus_tag="RD451_001209"
     CDS             complement(17452..18636)
                     /locus_tag="RD451_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HDT7566481.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(18661..19908)
                     /locus_tag="RD451_001210"
     CDS             complement(18661..19908)
                     /locus_tag="RD451_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HDT7566482.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            20123..21868
                     /gene="dnaX"
                     /locus_tag="RD451_001211"
     CDS             20123..21868
                     /gene="dnaX"
                     /locus_tag="RD451_001211"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HDT7566483.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            21888..22202
                     /locus_tag="RD451_001212"
     CDS             21888..22202
                     /locus_tag="RD451_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HDT7566484.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            22227..22823
                     /gene="recR"
                     /locus_tag="RD451_001213"
     CDS             22227..22823
                     /gene="recR"
                     /locus_tag="RD451_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HDT7566485.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            22887..23531
                     /locus_tag="RD451_001214"
     CDS             22887..23531
                     /locus_tag="RD451_001214"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HDT7566486.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            23546..23875
                     /locus_tag="RD451_001215"
     CDS             23546..23875
                     /locus_tag="RD451_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP receptor"
                     /protein_id="HDT7566487.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            23889..24827
                     /gene="holB"
                     /locus_tag="RD451_001216"
     CDS             23889..24827
                     /gene="holB"
                     /locus_tag="RD451_001216"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HDT7566488.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            24863..25687
                     /locus_tag="RD451_001217"
     CDS             24863..25687
                     /locus_tag="RD451_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HDT7566489.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            25680..26027
                     /locus_tag="RD451_001218"
     CDS             25680..26027
                     /locus_tag="RD451_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HDT7566490.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            26096..26968
                     /gene="rsmI"
                     /locus_tag="RD451_001219"
     CDS             26096..26968
                     /gene="rsmI"
                     /locus_tag="RD451_001219"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HDT7566491.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            27077..28198
                     /gene="dinB"
                     /locus_tag="RD451_001220"
     CDS             27077..28198
                     /gene="dinB"
                     /locus_tag="RD451_001220"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HDT7566492.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="RD451_001221"
     CDS             complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="RD451_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HDT7566493.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="RD451_001222"
     CDS             complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="RD451_001222"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HDT7566494.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            31657..32451
                     /locus_tag="RD451_001223"
     CDS             31657..32451
                     /locus_tag="RD451_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7566495.1"
                     /translation="MKNERGGEELEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGE
                     FVGIMGPSGAGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQ
                     EFNLIDTLNAKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQ
                     RIAAARALVVQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTAS
                     YCDRILFIKDGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            32441..34483
                     /locus_tag="RD451_001224"
     CDS             32441..34483
                     /locus_tag="RD451_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7566496.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            34764..34913
                     /locus_tag="RD451_001225"
     CDS             34764..34913
                     /locus_tag="RD451_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HDT7566497.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            34924..36438
                     /gene="dltA"
                     /locus_tag="RD451_001226"
     CDS             34924..36438
                     /gene="dltA"
                     /locus_tag="RD451_001226"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HDT7566498.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            36435..37640
                     /gene="dltB"
                     /locus_tag="RD451_001227"
     CDS             36435..37640
                     /gene="dltB"
                     /locus_tag="RD451_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HDT7566499.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            37685..37918
                     /gene="dltC"
                     /locus_tag="RD451_001228"
     CDS             37685..37918
                     /gene="dltC"
                     /locus_tag="RD451_001228"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HDT7566500.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWSTPNKIIQQATALKG"
     gene            37921..39189
                     /gene="dltD"
                     /locus_tag="RD451_001229"
     CDS             37921..39189
                     /gene="dltD"
                     /locus_tag="RD451_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HDT7566501.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            39330..40412
                     /locus_tag="RD451_001230"
     CDS             39330..40412
                     /locus_tag="RD451_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HDT7566502.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            40412..41215
                     /locus_tag="RD451_001231"
     CDS             40412..41215
                     /locus_tag="RD451_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HDT7566503.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            41285..42025
                     /locus_tag="RD451_001232"
     CDS             41285..42025
                     /locus_tag="RD451_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDT7566504.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            42036..43040
                     /locus_tag="RD451_001233"
     CDS             42036..43040
                     /locus_tag="RD451_001233"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HDT7566505.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(43085..44929)
                     /locus_tag="RD451_001234"
     CDS             complement(43085..44929)
                     /locus_tag="RD451_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566506.1"
                     /translation="MSFFNNIYNKKESFYLRIKWSIIIILSLLFLTGIAYFFYFIFSP
                     ADSNQMKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLEKPLDEANLL
                     IKGNHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTLTVSSPYQNY
                     AGLPPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMYKQKRLEYSL
                     ILLSCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYYWSRMFYYKK
                     WYGIFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLACIGEAYKNNR
                     FYVACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISYNLIDHILNT
                     DKDRRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLMHTDQTKAKN
                     YVEKILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLPEELPINDDD
                     LAQLLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYDTNLFSRGIT
                     EELDDQERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
     gene            45141..45659
                     /locus_tag="RD451_001235"
     CDS             45141..45659
                     /locus_tag="RD451_001235"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HDT7566507.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            45787..46470
                     /locus_tag="RD451_001236"
     CDS             45787..46470
                     /locus_tag="RD451_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HDT7566508.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKRLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            46779..46852
                     /locus_tag="RD451_001237"
     tRNA            46779..46852
                     /locus_tag="RD451_001237"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:46813..46815,aa:Arg,seq:tct)
     gene            47011..47370
                     /locus_tag="RD451_001238"
     CDS             47011..47370
                     /locus_tag="RD451_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 family protein"
                     /protein_id="HDT7566509.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            47493..49124
                     /locus_tag="RD451_001239"
     CDS             47493..49124
                     /locus_tag="RD451_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HDT7566510.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(49186..49827)
                     /locus_tag="RD451_001240"
     CDS             complement(49186..49827)
                     /locus_tag="RD451_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HDT7566511.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     misc_feature    50013..50089
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            50109..50417
                     /gene="rplU"
                     /locus_tag="RD451_001241"
     CDS             50109..50417
                     /gene="rplU"
                     /locus_tag="RD451_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HDT7566512.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            50444..50788
                     /locus_tag="RD451_001242"
     CDS             50444..50788
                     /locus_tag="RD451_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HDT7566513.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            50801..>51058
                     /gene="rpmA"
                     /locus_tag="RD451_001243"
     CDS             50801..>51058
                     /gene="rpmA"
                     /locus_tag="RD451_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HDT7566514.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKK"
BASE COUNT        16381 a         8847 c        10645 g        15185 t
ORIGIN      
        1 aataaaaaca ctaataaagg atagtacagt ataataaaaa ataaaaggta tctggtacga
       61 aaatcaacta gatacctttt ttgtgttctt atttttttgt tattttataa aaaatagaga
      121 tctcatgtta gaaaacctaa catatgcagt tgacaatatt ttttttaatt ggtacacttt
      181 agccaactta taaaacgaaa ggggacgtct gatgggagaa aaggaattgc gccgatctat
      241 gtccgtattt ccaattggta cagttatgaa gctgactgat ttgtctgctc ggcaaattcg
      301 ctattatgaa gaacaagatt tagttcatcc ggaacgaagc gaaggaaacc gacgtatgta
      361 ttcgctgaat gatattgata tgttgcttga gattaaagac tatctttcag agggattgaa
      421 tatggctggg atcaaacgtg tatacgaaat ggcacaggcg aaaaaacaag aagcaaaaaa
      481 caagaagccg ttgacagatc atgacgttcg acaaattttt cgtgatgaga ttttggcgca
      541 aggtgggtta agcaaaacag gtcattatca gtcgcaagga ttgcaaagac aattctttga
      601 ctgaataaat taaaaaagga agagggatac catggtaaag aaacagataa caggtgaaga
      661 aatcaaacga atcattgagg aagaaaacgt acgattttta cgattgatgt tcacagacat
      721 cttaggtacg atcaaaaatg tagaagttcc agtgagccag atcgacaaag tattagaaaa
      781 taaaatgatg tttgacggtt cttcgattga aggatttgtt cgaattgaag aaagcgatat
      841 gtatttgtat ccagatctct ccacttggat gatcttcccg tgggaaagtg ctcatggaaa
      901 agttgctcgt ttaatttgtg atatctataa tccggatggg acaccatttg ccggcgatcc
      961 tcgcgggaat ttgaaacgag cattgaaaga tatgcgcgac cttggtttta cctctttcaa
     1021 tttaggacct gaaccagaat tcttcttatt taaattagac gaagacggtg ggatcacaac
     1081 gaccttgaat gataaaggtg gttattttga ttttgcacca acagatttag gtgaaaattg
     1141 ccgccgtgac atcgtgttgg aattagaaag tctaggcttt gaagtggaag cttcacatca
     1201 tgaagtagcg ccaggacagc atgaaattga ctttaaatat gcagatgtgg tagatgcttg
     1261 tgataatatc caaaccttca agctcgttgt caaaacgatt gcacgcaagc atggacttca
     1321 cgcgactttc atgccgaaac cgttatttgg gatcaatggt tctggtatgc attgcaatat
     1381 gtctttgttc aatgatgaag gaaatgtttt ctatgataaa gacggtgaat tggaactaag
     1441 tgaaacagct tatcatttct taggtggttt gctgaaacat gctcgtgcct acacagccgt
     1501 ttgcaatcca acagtcaatt cttataaacg tctcgttcca ggttatgaag cgcctgttta
     1561 tgtcgcatgg agtggccgta atcgttcgcc attagtacgt gtaccagaat ctcgcggttt
     1621 atccacacgt ttggaattgc ggtcagttga tccatctgca aacccatact tggcaatggc
     1681 agtattgttg caagcaggac tagacggtat ccgtaatcag atcacaccgc cagcagctgt
     1741 tgaccgtaac atttatgtaa tggatgagga agaaagagaa gctgcacata tccaggactt
     1801 accttcaact atccataatg ctatcaaaga attgcgtaag gataatgtaa tgattgacgc
     1861 attaggacaa catatcttct caaattttgt tgaagcaaaa cgtctcgaat gggcggcatt
     1921 cagacaaact gtttccgagt gggaaagaga acaatatcta gaactttatt aaaacaggaa
     1981 taccgtgaat tagaggctgt gaaatcagcg ttttgacctg agtattagag aaactaacgg
     2041 aaaaatagtt cctcatattt tgccgttttt tgagctaata ccgagggtca gctgattgaa
     2101 caccgtttag tggagaggtt gtgaaaaagc tgccctgcaa caagtaataa gaatagccaa
     2161 gcaaaaacag cttttcttgt ttttgaattg gctgaactta ttaccgcaga tgcaagcttt
     2221 tgaacaccgt ttaccaagag gttttgaaaa agacgtttag tttcgagtat taagaaaaat
     2281 tttgtgaaaa tggctttcta catttttgca taaatttggc ttaataccga gaaactggct
     2341 tttgaatacc gtttatccag aggttgtgag cctaccattt aactccgaat cacaagaaat
     2401 aatttcaaaa acagcttctc atgtttgatg gatattgtga cttgtgaccg aggagttggc
     2461 aggagaacac cgtttattta gaaataagga ggcacgactt ttgtcgcatc tccttatttt
     2521 ttacttatgt gattcgttac cttcaatgaa tccctacaag gcacttttgt tgaaaaaaag
     2581 gtcatctttg aaaaaattag tggaattgtt ttgtttttga tattatttaa tagaaaagat
     2641 atgccaaaaa tccgagaact gtggactacg ttttttacgt aaaggaggta aataagggtg
     2701 aaagaaaaag attgtttcta cgataagcta tataaactgt tgctgcaagt aggaaaaagt
     2761 agttctttgt taggtgggat attatctatc ataatgtttg ttttattttt ttatctatta
     2821 tttcacttaa aatttttcag taacgatttt ctgatttgct taggtttaac gttagctatg
     2881 tttatatcaa gcttattatg tgggttaaat tttttttgca ctcataaagg acttaagaaa
     2941 taatttctca aaggatatcg aaaaagaaaa aattgtaagc ggatagtatt catttgagta
     3001 cttgactttc ccttagtcag cttgtattat acaccttggg caccctttta gagggtcaga
     3061 agtttacaga aatttcggct ccctattctt attgaagaat agggagcttt gtttattgtc
     3121 tgagactttt cctgcacata aattaaaaag gagtttttga acttatgaca aaatatattt
     3181 ttgtgaccgg cggtgtcgtt tcatcaatcg gaaaagggat tgttgcagct tctttaggac
     3241 gcttattgaa aaaccgcggc ttaaaagtaa ctatccaaaa atttgatcca tacatcaacg
     3301 tggatccggg gacgatgagc ccatatcagc acggagaagt attcgtaaca gatgatggtg
     3361 ctgaaacaga tttggatctg ggccactacg aacgttttat tgacatcaat ttgaacaaat
     3421 actccaacgt gacgacagga aaaatctatt ctgaagtttt gcgtaaagaa cgtaagggcg
     3481 aatacttggg agcaactgtt caagttattc ctcatattac aaatgagatc aaagaaaaaa
     3541 tcatgcgagc agctaaaatg actgattcag atgtgatcat tacagaagta gggggaacag
     3601 taggggatat agaatctttg ccattccttg aagcacttcg tcaaatgaaa gcagatgtcg
     3661 gtacagataa tgttatgtat atccatacaa cattgattcc ttacttgaaa gctgctggag
     3721 aaatgaaaac taaaccaacg cagcacagtg taaaagagct acgtggttta ggtatccaac
     3781 cgaatatttt ggtggtacgt acagagcaac ctgtttctca aagcgtgaaa aacaaattgg
     3841 cacaattttg tgatgtcgaa ccagaagcag ttatcgagtc gccagatgta gatacacttt
     3901 actccatccc attagtttta caagcacaag gaatggatca aattgtttgc gaccatttaa
     3961 aactagatac accagaagca gacatgacag aatggaaaga attagaagaa cgtgtcttga
     4021 acttgaagaa aaaagtacgg attgcgcttg tcggtaaata tgtcgagtta ccagatgcat
     4081 atatctcagt agttgaagca ttgaaacatt ctggtttcgc ctataattca gacatcgaga
     4141 tcgattggat caaagcacaa gaattaacga gagaaaatgt agaagaacgt ttgaaagacg
     4201 cagatggaat cttggttcct ggtggatttg gtgatcgcgg agtagaaggg aaaatcgaag
     4261 cgattcgtta tgctcgcgaa aatgacgttc cgtttttagg tatttgtctt ggtatgcaga
     4321 tggcttgtgt cgaatttgca cgtaacgtcg ttggattaga agatgcgtca tcagctgaaa
     4381 cgaatccaga tacagcaaac aatattattg atttaatggc tgatcaggaa aacatcgaga
     4441 atttgggtgg aactttacgc cttggattat acccatgtaa aatcaaaaaa ggaacgaaga
     4501 cggctgaagc atatgatgga gccgatgttg tgcaagaacg tcaccgtcac cgctatgagt
     4561 tcaataacaa atatcgtcaa ttgtttgaag aacaagggct agtcttttca ggtgtctcac
     4621 cagataaccg tttagtagaa atcgtagagc tgccagagaa aaaattcttt gtgggatgcc
     4681 aattccaccc agaattgatt tctcgtccaa atcgcccgca aaaattaatc aaagcatttg
     4741 tcggagcatc attagcagat cacgaaacaa aataattttt gaacttgata gaaagagaaa
     4801 agtagcaaga gaaggggata agcaattttc ttgtcacttt tctctttttc tgatttgtta
     4861 ttatttgtag gaaaaaagat agaaagcaaa agactttttt cgattaaagc gctattggat
     4921 attttatttt ttgcaaaaaa cttcttgaaa attttcattt tcattgattt tagtagaaaa
     4981 ctaccgaaat gtttggtaaa atagggtcgt tggttaagaa ttgtcttaac aaatttagtt
     5041 ttacaaaact taggaggaat tttattatgc cagtagtatc aggagctgaa tttttaaaag
     5101 ctgctcgtaa aggcggttac gctgtcggcg gattcaacac aaacaacttg gaatggactc
     5161 aagcaatcct tgaagcggct gaagcaaaac aagcaccagt acttatccaa acatcaatgg
     5221 gtgcagctaa atacatgggt ggttacaaaa tctgtaaaga tttaatcact gatttagttg
     5281 aagcaatgaa catcactgtt ccagttgcta tccacttaga ccatggtgat tacgaagctg
     5341 ctttggaatg tatcgaatta ggctatactt cagtaatgtt cgatggttca catctaccat
     5401 ttgaagaaaa cttgaaatta gctaaagacg ttgttgaaaa agcacatgca aaaggtatct
     5461 cagttgaatg tgaagttggt tcaatcggcg gagaagaaga cggaatcatc ggtaacggcg
     5521 aattagctga tattgaagaa tgcaaacaaa tggttgctac aggtatcgac tacttagctt
     5581 gcggtatcgg taacatccat ggtcaatatc cagaaaactg gaaaggatta gcttttgacc
     5641 acttacaagc aattgctgat gctgtaggtc cagacatgcc tttagtatta catggcggat
     5701 caggtattcc tcaagatcaa atcgaaaaag ctatctcaat gggtatctca aaagtaaatg
     5761 ttaacactga attccaatta tcatttgctg cagctactcg taaatatatc gaagctggta
     5821 aagataaaga aggtaaagga ttcgaccctc gtaaattatt agctccaggt aaagcagcaa
     5881 tcgttgaaga tgctaaatct catatcgact ggttcggttc agctaacaaa gcgtaagcat
     5941 ccacataaca gatacgatat ataggaatgg agaacgactt ttgaagtcgc tctccattct
     6001 tttttactta aaacggcaga ccatgctcgt ttcttttttt tatctatgat aaaatacaag
     6061 catatccatg aaaaaagatt aataaacaag gtggaaacag atgaaaaaaa tcgtaatcaa
     6121 aggaaaccga cctttagctg gtgaagtaac gatcagcggt gcaaaaaata gtgcagtcgc
     6181 attgattcca gctgcaatct tagctgattc cccagtgatc ttggaaggtg tgccggacat
     6241 acaagatgtt cattcattaa ttgaaatttt agagatcatg ggcgcaactg tccatttttc
     6301 caacaacata ctagaaatcg atcctcgaga agtcgtatcg attccgatgc cgcacggaaa
     6361 aatcaatagt ttgcgtgctt cttattattt tatgggaaca ctgcttggta aatttggcga
     6421 agcggtagta ggcctgccag gtggctgtta tttaggccct agaccgattg acctacacgt
     6481 caaaggattt gaagctctag gtgctgaagt gacaaatgaa catggtgcca tgtatttacg
     6541 gacagaaaat aaaggattgc gtggcaatcg gattttcatg gacgtggttt cagtcggagc
     6601 aacgatcaat gtgatgttag ctgctgtaaa agcaaaagga cagacagtaa ttgaaaacgc
     6661 tgcacgagaa ccggaaatca tagatgtggc aactttactg aataatatgg gggcaaaagt
     6721 tcgaggagcg ggtacagatg tgatccgtat cgaaggagtc gaaacattac atggctgtcg
     6781 gcatttcatg attcctgacc gcatcgaagc aggaacctat ctagcattag cagctgcagt
     6841 aggaaatggt atcaaagtga aaaatgtgat ctttgaacat ttggaaagct ttatagcaaa
     6901 attgcaggaa attggtgtcc atatgaaaat cagcgaagat gaaatcgaag tttacccctc
     6961 gaaagaatta aaacccgcaa acatcatgac ctatccttat ccaggatttg ccacagatct
     7021 gcagcagcca cttactgcgt tactattgat gactacaggc acttcagaaa tcatcgatac
     7081 gatctatgcg aaacgtgtga accatgtgcc ggaactagca cgaatgggcg ctgatattac
     7141 cgtggaagga aatatgatca tcgtgaatgg tccaaataaa cttcacggca cagaagtcgt
     7201 ggcttctgat cttcgggcag gtgcttgttt agtgattgct ggactattgg cagaagggac
     7261 aacgacgatt tacaatgtag attatatctt acgcggttat gatcatatta tcgagaaact
     7321 aacagcctta ggggcatcaa ttgaaatgat agaggaagtg ggagctgaat gagcgattat
     7381 ttgacaatgg cagaactaga gaacaaaacg ttaaaagaag tttatagtta tgccaaagaa
     7441 tttaaaattc cttattacag taagatgaat aaaaaggaat tatctctagc tgtgattcgt
     7501 gcacaagcag agaaacaagg attttattat atggaaggaa tattggatat cgttggtcaa
     7561 gatggttacg gttttttacg gccaatcaat tatggaccaa gtgcagaaga tatctatatt
     7621 tctgcctcac aaatcagacg attcagtttg agaaatgggg acaaagtggc aggaaaagcc
     7681 cgtccaccta aagaatcgga acgttattat ggtttgatgc acgtggaaag cgttaatgga
     7741 aaagatccgg aagaagcaaa agaacgtccg cattttccag ccttaacacc tctttatccg
     7801 caaagacagc ttcaactgga aacaacaccg caaagactat ctacccgaat gatcgatatc
     7861 ttttctccaa tcggttttgg tcagcgtgga ttgatcgtcg caccgccaaa agcagggaaa
     7921 acttctgtat taaaagaaat cgcaaatggt atcaccgaaa actatccgga agtagaatta
     7981 atcgttctac tgattgatga acgaccggaa gaagtaacgg atctagaacg aagcgtgaaa
     8041 ggcgacgtgg tatcttctac atttgatctg cagccgcaaa accatactcg agtttctgaa
     8101 ttagtattgg aacgcgcaat gcgtttagtc gaagataaac gagatgtcgt tatcttgatg
     8161 gatagtatta ctagacttgc tcgggcctat aacttagtcg ttccaccaag cggacgtaca
     8221 ttgagtggcg ggattgaccc agccgcattg tataaaccta agaaattttt cggggcagca
     8281 agaaacatcg aagaaggtgg cagtttgacg attttagcga ccgctttagt cgatacagga
     8341 agccgtatgg atgacgtgat ctatgaagaa ttcaaaggaa ctggaaatct agaattacaa
     8401 ctttcacgtg aattatctga acgtcggatc ttcccagcca tcgatatcaa aaaatcaggt
     8461 acccgaaaag aagaattatt gatgccaagt gaagaattag aagaaatttg gaaacttcga
     8521 aaaaatatga ctggagattc attagaatat acggaacaac tgatccgctt tttgcgtaaa
     8581 acaaaaaaca atcagcaatt tttcaaagaa tttcaagatg tctcctttgg taaaaaaaat
     8641 ccgaccagaa atctgaaaag ataattgcaa ccttgactga aacatgttaa gatgttaatg
     8701 ttgtaaatcg acaaatcaac tctggttcag caaatggagc agggcaaagg agcgaaaaaa
     8761 tcatgaaaga aaacatccat ccagattacc acccagtagt attcatggat tcaacaactg
     8821 gtttcaaatt cttgtcaggt tcaacaaaaa cttcacaaga aacagttgaa tgggaagacg
     8881 gtaatacata cccagtcatc cgtgtcgaag taacttctga ctcacatcca ttctacactg
     8941 gacgtcaaaa attcacacaa gcagacggac gtgtggaccg tttcaacaaa aaatacggtc
     9001 tcaaagacgc aaacgctgcg gaataataaa aacgctgata actcaacgtt tagcagacta
     9061 tctgataggg atagtctgtt tttttatgtt ttttgccaat ttaaaacttc gtttgatgct
     9121 gaaaaagtcg taggatcata atgcacaaaa caatgaaaaa ctagtatata gttttaatta
     9181 tccacttgat aaaaacacct tatattaacg aaatgaagag gggttatttc gaagtaaaaa
     9241 accatttacc taaaattaga agctaagctt tcctttcaag gaaggctttt tgttttgtta
     9301 tagacttgcg attgtttgtg agctagatcg ttcattttaa tgacttatac acgcggatga
     9361 tgggtctttt tcctctgttc attcataata ttgaacggta cagctagcga tgctatactg
     9421 acctcagttc caagaaaacg ttaacatttt ttgtggggga gaggtttttt atgaggtttg
     9481 atcaattgat cgcagaagaa ctgattgttt tcgatccatc gatagattca aaaggatcat
     9541 tatttgagcg aataggggat gtgttgaaaa aaacaaataa ggtaagaaat gttcaaaaag
     9601 tcgttaaggc actattcaaa cgagaggagg agatctccac aggaatagaa gatggatttg
     9661 ggattcccca tgcaaaaagc aaatatgtga caaaaccagc actgtgtttt tttcatacag
     9721 ccaaattaac ggactatagc gggatagatg aaatgccaat tgaatatatt tttgccatcg
     9781 tagttcctga aaaatcagca gatatgcatc tagagattct cagcacactc tccagacgat
     9841 tgatgaatgc agattttaga aagggaataa aagaagccac tacgccagca gatatcatca
     9901 gacagattag tcaagaatga aaatagtaga gtctttgtcc gagtatcgat agtgaagaaa
     9961 aaggaggaaa ataatcatga aaatcgttgg tgtaactgct tgcccgactg gaattgctca
    10021 tacttatatg tcggcagaaa aattagaagt aacagcaaga aatctaaacc atcaagcaaa
    10081 attcgaaaca caaggtgtaa aaacagaaaa tcagttatct gaacaagaaa tcaaagaggc
    10141 agatgcaatc attcttgcag tagataaaga aatcgaattg gaccgatttg ccgggaaaaa
    10201 agtaaagcgt gtctctacaa gccgagcaat caaagaaccg caagtagtaa tagacgaagc
    10261 attgagagat attggcgtat tcgttgtgtc taatgaaaaa gaaccagctg caaatgagaa
    10321 aaagccgaca atctataatc atttcatgaa tggtgtgaat tacatgcttc catttgtgat
    10381 cgcaggcgga atcatcatcg cactgagttt tgcctttggg attacagcgg ctgatcccaa
    10441 ctcagcagac tataatgtgt tagcagctgc attttcaagg atcggaggag atacagcgtt
    10501 tgccatgatg gttcctgcgt taggcgcggg gattgctaca tcgattgctg gaaaagcagg
    10561 ttttgcccca ggaattgttg ccggattact ggcctctaca ggtggttcag gttttcttgg
    10621 cggaatgatt ggtggcgtgc tagcagggta tatctgtgat tttctggcaa ataaaattag
    10681 cgtaaaaaaa gaattttctg ctatttatca gctgattgtc gtcccctttt tatcgatctt
    10741 aattattggg cttttgatgg tatttgtgat tgaacaaccg atcacatggg tgttggatgc
    10801 tttgacaaat tggctgaata gcttgggaaa tacatccggg ctattgttcg gattacttat
    10861 cgggatcatg atggcagctg atatgggtgg gccgatcaat aaatcgactt cgactttctc
    10921 gatcggtttg atgtcagctg gagtaaatgc accgattgct gcttgtatgg ctgcaggaat
    10981 gacacctccc ctaggtattg ctttagccac tttattattc aaacataaat ttaccaaaga
    11041 agaacggact tcaggtcaat catgctggat tttaggcgct tcgtatatta cagaaggtgc
    11101 tataccgttt gcggtatctg acccgatccg cgtgatacct agtttgatga caggttcagc
    11161 agtcgctgca gggatttcca tggcagtagg agttacttca atggcacctc atggagggat
    11221 ttgggtgatg ctaattccaa atgttatgaa caatttacct atgtatgtct tggcaattgc
    11281 atcaggtaca gtcactacag cctttatgct tggactattg aaaaaaacag tgaaagagaa
    11341 aaaacaagac aagtggacga aaaatgaaaa tctaacaaat gaggtggaag cgtaatgtta
    11401 tatacaatga aagagttatt gaaagtggct aaagagaatc aatttgcagt accagccttc
    11461 aatatttgca gctatgatat gatgaaagca atcatcgaag aagcagagag attagaagca
    11521 ccagtaatct tagaaattca tcctgatgaa atcgcctatt taagtgatga gtttgttgcg
    11581 gcagtaagag cctatgctta tacaagtaaa ctgccgatcg ttatccactt ggatcatggc
    11641 ggtacgatag aagatgtctt acgggcgatt cgaaacggct attcttccgt gatgatcgat
    11701 gcgtctttga aatcattcga cgacaatgta cagattacga aaaaagtggt tgcgttagct
    11761 catgcggtaa atgtctcagt ggaggctgag cttggaacga ttgggaataa tggttctgct
    11821 gaaggaggtg ctgaaacaat catttataca gatcctgatc aagcgaagat ttttgtgaaa
    11881 gaaacaggaa tcgatacact tgctgtagca attggaacag cgcatggctt gtatccgaaa
    11941 aacagaactc caaaattaaa tatcgactta ctgaaagaat tgaaccaaca aatcgatctt
    12001 ccatttgttt tacatggcgg ttcaggtaat ccggacgcag aagtcagcga agcagtaaaa
    12061 tacggagttg ccaaagtgaa tttgagctca gatcttaaaa gcgtcttttt caatgctttg
    12121 agagaaatat tgagtgaaaa tccatcgatg tacgagccga atgcaattta tccagcagct
    12181 aataaaaagg tacaagaagt ggtcaaacat aaaatggaaa ttttgaacac agtaggcaag
    12241 gctagtttat actaaaaata aaaatgtgtg gtcaagaggg tatgacaata gtcttgtcat
    12301 accctcttaa ccacacacga tgttcagaag tagttttttc gaaaaatttc ttcttatttc
    12361 tcgaagccaa tcacttctgt cacaacctct tttttcctgt tactatataa agtaaatggg
    12421 gtgattttat gttgaatgaa gtggagaata gacagcagga gattgtgaat tatctaaaaa
    12481 acaaccaatt tgcaagagtc accgatttga tcgagttagt aaattatagc gaagccacga
    12541 ttaaacgtga ccttgttttt ctggaaaaaa gtggattgat ccgtagagtt cgcggtggcg
    12601 ccatgcttat tgacaatcga aaaattgacg tgccttacct gatgaagatc accaaattag
    12661 aagaagaaac agaaaaacgt aagattgcag atacagcttc ttctttgatt cgagatgata
    12721 tggtcttatt cttggattcc agtacaacct ctttacactt agtcagaaac ctagcaagat
    12781 ttgatggttt gcagatcatt acgaatggca tcgtcacagc tgctatgttg agtgaatata
    12841 caacggcaaa agtatctgta ttgggagggg caattgttcc gaaacgagca acaatcaacg
    12901 gttcaaaagc ctataacgat gcattgtcat attatgcgga tttagcgata atgagttgtc
    12961 gcgggctaga tttcagccaa ggagtaacag aaactcatga aggagaggca atggtcaaaa
    13021 aagcttttag aaaacaatca gaccggcttg ccgttttagt tacacagcaa aaaattgcac
    13081 ataaattcat gcatcaagcc attgcttttc atgaaatcga ttatctggtg acaagtaaag
    13141 aactgacaaa agaacagtat gcgaaagtaa aggaacacca tatcgaatgt ctgtacggat
    13201 aaattattac gtgaatgttc taagtggctt cctcattttt agataggacc ttatctttgc
    13261 tcgcttctct cagccgatgg tataataatg aaaaggttat cttgttagat aatcttactt
    13321 ttttatccag gagaaaggag tgcagaaaat gaaacatgtg aaggcgttgg tagtgaaggc
    13381 aatcatgatc tgggcgattc tgtgggtcgt gctgacaggt ttatacggtg ttagctttat
    13441 ggattcaacg attgttgggg taattattgt agtcatgatc tatgtgctag gggatctgtt
    13501 gatcttacgt aaagtaggga acatcgcagc gacgatcgca gatgctggtt cagctgcagt
    13561 tatcttgtgg ctctatctat attttatgaa tgatacagtc gatatttgga tgaaagtatt
    13621 gattcctgct ctattgatcg gtgtggcaga atggttcttc cacaagtggt tgctaagtca
    13681 aggcatcgta ccagatgaac ggaaaatgga ataaatcaac agttaaacta ttcttatcga
    13741 taaatgaaag ctttaaaaat aaatagatgt ttaattaaga ataatcataa actattttta
    13801 ctcaaaaaac cgctcagatt attttcagat ctgaacggtt ttttttatct attcatcaag
    13861 atcaaatttc atttttcaat gattcaatca attcgccctc tgcttcatga ctatgttttc
    13921 ggccattaac aagatagagt gctgtacata tcaatggaat gactccggca atcacataca
    13981 atcctctaaa tgaagtaaga gattttagca tccccatcaa ataaggacca acgcctaagc
    14041 ctaggtctaa accaataaag taggtagata aagcaatact gattcgatgt tcgcggacga
    14101 tttttaaaca aacagcctgt ccatttgaca taaacgtacc ataacctagg ccgactaatg
    14161 ctccagagat aagcaatgtc acactattcg tcgttacact cagtaaaaat aatcctgctg
    14221 ttaagaataa atagctagga tacatcacgt attgttctcc tttgacatcg aaaatccttc
    14281 cagtcaatgg acgtgtaaat gtgatgacca aagcatatac gacgaagaaa aatgacccag
    14341 cagcaactaa gtggattact tttgtataag aagataaaaa tgataaaaca cttgaataag
    14401 aaagacccat caaaaaggca attcctgtaa tgaaaagtgc tttcttttca ataaaactat
    14461 tgatattcca tgagcgaaga gatatttttt gttcttcaga taatggaata ttttttacag
    14521 gaaagacaag gcaggcaatc gtaacaaaga agaccagtac aattgaaaac cagataatga
    14581 aacgaaaatc agtcatattc agcaaaatca ttcctaaaaa tggcccaaca gcggcagcta
    14641 aactagtact taatccataa taattgatgc cttccccttt tttagatgca gggatatatg
    14701 cagtaacgat agcatttgta gctgtagaaa ctgtaccgta gccgaatcca ttcaagaatc
    14761 gaactaaata caatgccccg atagttggcg tataaagata tgctaatgtt gaaaggagat
    14821 agaagatcgc gccgcctctt aaggtaaact tccgaccaaa tagttctaac tgtttcccca
    14881 tgaataagcg tgccagcaat gttccgatga tatagatccc agaagcaaaa cctgcttggc
    14941 tcaagctggc gtgtaaggtg tcttgcgcaa tgactgccat gatgaccatc aacagataat
    15001 aaatcaggta gacaataaaa ttgatcaatg tgattccaat aaaatattta ttaaataatt
    15061 tcttttccat gtatgttata cattcccctt aagctgaata tgcttttaat ttttgtattt
    15121 gaacttctac atcgtgataa ttggatggat agcgatcaac aagttggcga ataaataaat
    15181 ctcttgtaga cataaacaga tttaaaaatt cttcgcattc gtttgttgga ttctcatcca
    15241 ctgctttgat caattcgatc gagttttgat acgcatcatt taaaaagact aaagaagctt
    15301 tcatatcaaa tcttgtttga tatgctgttt ctaatcgatt aatgattgtg ttcatccagt
    15361 aattcatgtt ttttccctct attcttaaaa aattttactt ctgcagtata acgaataaaa
    15421 aaaaggaaaa aaatcgcata agtgatggaa aaaggtactt aacaaatgtt aatatcatta
    15481 gtaaaatacc tttggacttt aaaaagtttt aaagtactgt atgatctttt tagatgaaag
    15541 tttggatggg ggagcatcat tggatagtag agtcttaaag gaatatttgg ataaaaatga
    15601 ttttccgatt atacgcaaag gatatcataa atatttgaca ttcgaaggga tggaagattc
    15661 ccatacgtat atcttgaaag agggaacggt aaaagcaagt gttatttcaa atgatgggag
    15721 agaatttaac cttcgctata tcaaagatct tgaaatcgtc tctcttttaa aagacgaata
    15781 ttcacaattc atcgattcgc cgtataatat tcgagttgaa tcagaatatg cagagtttta
    15841 tcgaatcaat cgtgtgcgct tttggcaaaa tatcaaccaa gacccaaagc tacaacacta
    15901 tgtaaaagag tattaccgct atcgtctgct ttattcgatg aaaaaaatgc agcaaatgct
    15961 attaaacgga aagctgggag ctgtttgtac gcaactttac gaattatatg atttattcgg
    16021 tgtgcggaca gaagaaggga tgctgatcga tttttcgatc acgaatgaag aaatcgccaa
    16081 attttgtggc atctcaactg ctagcagtgt aaacagaatt ttaaaacaac tgaaaaaaga
    16141 tggtattatc accgttaaag accatcatat cgttattttg aatatggact tgttagaaga
    16201 caatattatc ttttgatgaa caaagaggtt gtgaaatcag cgttttgacc tgagtattag
    16261 agaaacaaac ggaaaaatag ttcctcatat tttgccgttt tttgagctaa taccgagggt
    16321 cagctgattg aacaccgttt accaagaggt tgtgagcctg ccgtttaact ctgagtcaca
    16381 aggaacaatt tcaaaaaaca gcttttcatg tttgatgaat attgtgactt gtgaccgagg
    16441 agttggtagg agaacaccgt ttaccaagag gttgtgaaaa agctgttctg catcaagtaa
    16501 taagaagagc caagtaaaaa cagtctctta tgtttttaac ttggctggac ttatcaccgt
    16561 agatgtaagc ttttgaacgc cgtttatttg caacaaaagg ggctgtgaca cgatttttgt
    16621 cacagccctt tttttgcgaa cattcattta gcaattttta gaaacttctg ccgccaccgc
    16681 caaaagtccc gccaccgcta gaatgggtag tacttccgcc accgccgctt ccaggaggtg
    16741 ggcttttggg gattcttctt gtcgtgacaa aagaatttgt cagacgatcg gttttttcag
    16801 ttaatttgat actggatttt tctcggaatg gatatttgta gatgcctgat ttcaattgat
    16861 aacgcgaaac agtcacaaaa taaaagacaa gactaaggat aagagccaaa acaacagcaa
    16921 tgatgatttc tactgtcgtc aaaaccttat agcgtgtaat tttgccagtt tcttcgtcta
    16981 cacgataatg tcctcctgga actccgtctt ccacatatgt tgctgattta gacaggtaag
    17041 cttttgcagc attgtaatag gcagcatttg tcatctgatc ataaacatca tctaagatcg
    17101 aatcgattct gctatcagtc aaataatcga tcatattacc agaagtcgaa atgtagattt
    17161 cacgctgtcc catatctaat agcaatactg agccattttg atcatttccg actgcgtctc
    17221 ttaagtaatt atcagcaaag tctcttggtt cttctgaatt agatgtagtc gttacgatca
    17281 agactcgtcc tttgattttt tcattcagct tttctgcctg ttgttccaaa gattggattt
    17341 gatctgttgt gaataaccca gcctcatcat ttaccgtagc tgtatctgca tgagtagcca
    17401 ccggccagcc aacacttact agcaaaagaa agaataaaaa aaattttttc atcatatcaa
    17461 gtaacctccg atcagaaaga ggatcgctag cccagcgaaa atcccaagag cggtcagtcc
    17521 caattttttc tggctgatcg gcaggacacc gctgaccttt cctgtttgtc cattcattgc
    17581 gtagtagtag acttttttac ttgagtcatt gcttcgataa gtaacaagcc ataccggcag
    17641 taatacgtaa ttatttactt cgtttgtgat tgaagcagaa gttcgcacac cggtcaatgt
    17701 tgtatatcca tttgcggtat cttttaacag cttctctgaa tagtctttta attcagattg
    17761 aatctgtgat ttgattgcct catattcgat atctcttttt tctgcttgga acccggctaa
    17821 atactggctt ttaaaatcaa ttgctttatc taacgggaaa ggttgcacgc cttcgaccat
    17881 cttttgttgc gtattttttg ataaggcatt ttttactagt tctttaaaag aaagcttgcc
    17941 tgctcttgaa acagcaaatt gcttcgtttc tgtgtattcg atgtcaccta tccgccatat
    18001 gcggataact gtaccattcg cctgcatggc accatctact tcagcatctg tagcccaata
    18061 agggaaatac acacctgtca acttatcgat ttgatcctta ttgaaaaaag ctttgggaac
    18121 aaaccatttt ttcttggtcc aagcgagaaa tctgttgatt gcttcttctt tctcgacagc
    18181 aaaaggaagt actttatttg gcaagaattc tccgcttaaa cgtcccgata gtacgacggg
    18241 attatggcag tagtaacaat aagtcgcagc agttgtcgca tcagtcacga tctctgcacc
    18301 acagttggga caaagaaaaa gatctatcgc tgcggtatta tctgcagatt cgtccgctgt
    18361 atctgaaaaa ccgcctgcct cgtcaaccgc tttgcgctcg gcttcattca tatcggcaag
    18421 ctgttcttgg gctgtaaaag taaaatcttc ggtaggtgaa ggttcttctt tgctttcttc
    18481 gccagccata cgcgcttctt tttgcttttg ctcatattgg ctgacttctt cttctgtata
    18541 gatattcagg cagtattcgc aatgaaattt ttggtctttg ggatcaaaag tcaacggacc
    18601 gccgcaatta ggacatttat gtgtaagaac atccatcagc tgcacacctt tctaaataaa
    18661 ttaattaacg gggattcctt taaacggttt accacagttt ggacagaatt tagggatgcc
    18721 gttggaaaga tccacgatct cattgcattc actgcatcgc atttgtagct taggctgaac
    18781 gttttctaca ggtttggcag ctccgcagtt ggaacagaat tttccggaat tttctgtccc
    18841 gcaaactgga catgtccaag tatccgcatt tccttgtgca gtttgttgat tttgtttttc
    18901 tgcttgttgt ttgatttgtt cttggttatt ttgagctgct tgagaaagat aagaaccatt
    18961 tgcattcatt cccataccta cacccataaa gccggtcatt gctcctgctt cattttttcc
    19021 ggctgcttcc ataccacgtg caatggaacc ttgcacgtat ccttcacgta cgctaggatc
    19081 acctagcatc gccccttcgt tacgcatatt gatcagtttc acagaatcat cggtgtaaga
    19141 aatgctggct acagccacag aaacaatctc catcccacgt aattcacgcc aagaatcatc
    19201 caatgcagta tccatgtatt tgcttaattc caaactctta gatggtacat aagaaatccg
    19261 ttgaccatct gcagacatct gattgattgc tgattgtagc gctgttagga attcagctaa
    19321 atactgctca ttgatatcat tgatttccac ttgtgttttg tttttaggga ttgcgtttgt
    19381 ataaaataaa atcgggtcaa cgacatgaat agaataagtg ccatgtgccc gtaagaataa
    19441 ttctgcgtta tagaaattgt caaagtagtt caacggcgcg cttgtaccga atttgattcc
    19501 ctttatttct tggagattga tataaaaaac ttgttgtttc tgcggtgtga cgccgccaaa
    19561 tttgaatcgg tcaaaagttt cagcaattgc ttctttcagt gttccattga acatggaagg
    19621 agctgcgtca tttttaatgg tgtaataacc ttcctcagcg gtataatcga tgatttttcc
    19681 accatcgacc aaaagcatca tcatgtttgg atagacatgg acgactgttc cgtctgttaa
    19741 aacatcttct gttcctttac gattggagcc acgtttgtca tctttgcgga ctttgacacc
    19801 ttttgtcatg accgttgtat cactcatatt gtctggttcg atgacttcta gccattgatc
    19861 tgccagaccg ccgccaacca tacttgttgc tgctttgata agacccataa aaaattcctc
    19921 ctctgattca gctagtgcca aacaattatt gtttatttat tataccatag gaagatgtga
    19981 aacttctcgg actagagacg gaattgaaat ggaaaattgc gtattgttta aatacctgaa
    20041 aaagccgaga aggatagtag tttttttacc taatatcacg tataataaga gatagtgaat
    20101 tttttaaaaa agggggatcc ttatggcata tcaagcactt tatcgagtct ggcgttcgca
    20161 gcgtttcgaa gacatcgttg gacaaaaagc tgtgacacag acactaaaaa atgctattgt
    20221 ttcccacaaa acctcacatg cctacttgtt tacaggaccc agaggaaccg gaaagacgag
    20281 tgcagcaaag attttcgcaa aagcaatcaa ctgtccgaac agtaaagacg gtgagccatg
    20341 caacgaatgc gaaatgtgtc gatcaattac tgctggtacg caagaagatg tgatcgaaat
    20401 cgatgctgcc agcaataacg gagtcgaaga aatccgattt atccgtgatc gggcaaatta
    20461 tgcgcctaca aaggcagcgt acaaagtgta cattattgat gaggtacata tgctttcaac
    20521 aggagctttc aatgccttgt tgaaaacatt ggaagagcca aaagaaagtg tcatattcat
    20581 cttagcaacg accgaacctc acaaaatacc agctacgatc atttcacgga ctcagcgatt
    20641 tgattttaaa cggatcaata cggcagatat tgtcgaacat cttgaattta tcttgaaaga
    20701 atcgactatc agctatgaac cagctgcatt gaatgtgatt gcccgttctg cagaaggcgg
    20761 gatgcgggat gcattgagta ttcttgatca ggcaatctcg tttagtgaag gaacaattac
    20821 tttagatgat gccatgcaag tgacaggtag cttaactgac gaaatgatgg acagttactt
    20881 gagtgcttgc gtgaaaaaag aagtaccaga agcattggaa acattgaacc aaattctcgc
    20941 agccggcaaa gaatcacgtc gctttctaga ggatatgtta caatactgcc gtgacttgct
    21001 gatgtatcag caagcaccta acctagttga ggaacaatcg agtacgatca gaagtacatt
    21061 tacagaattg gcacaaactg tttcagcgga tcagctgttt tcaatgataa agattttgag
    21121 cgatactcaa aatgaaattc gttttaccaa tagtgccgct atttatttgg aagtcgctac
    21181 agtcaaactt gcacagctac cgtctgcttc tgttccttca gcagatgtag catttgcaga
    21241 tgatcagata gtaaaacagc tacaacaaga gattaaggaa ctaagaaacg aaatcaagga
    21301 actacgcagt aatacaggaa ttgagaatac aaaagtacag ccggtacagc aaacaaatca
    21361 taaaaaacag acaagtacct atcgtgtacc gacggaacga gtatataaag ttctgcggga
    21421 agcgacaaga cagcatctga accaagtaaa agaagtatgg gaagacttgc tgatgagtct
    21481 atctgtcact cagcgagcaa tgcttaaagc aagcgaacca gttgcagctg gacctacagg
    21541 actagtgatt gcgtttgatt atgagattgt ttgtcaaaga gcagcaaatg acgaagaatt
    21601 gcagctttcg gtacacaaca acttaagccg aatgatcaaa gattatgcgc ctgatcctgt
    21661 ttatattaca agagaaagct ggccagaact tcgaagaaat tatttgacgc aggcacaaga
    21721 agagggaaca gaaaactctt ttgcttctga agactcagaa ggagaaatcg agttgcttcc
    21781 tcaagaacaa gaagtaccag aagaaacact tgtagtaaaa gcagaggaac tgtttggctc
    21841 cgaagctgtt acagtggtag atgattaata aaaaggagta gataattatg atgcgtggaa
    21901 tgggcaatat gcaaggcatg atgaaacaag tacaaaaaat gcaaaaagaa atggcagaag
    21961 cacaagagct gctaaataaa acagagttta caggtaaagc caccaatgaa ttggtcaaag
    22021 cggtttttac aggcgatcgt cgcatgaaag atatccaaat caatgaagaa gtcgttgatc
    22081 ctgatgatat cgagatgctt caggatcttg tcgtaatggc agtcaatgat gcgatcgcac
    22141 aaattgatgt ggaaactgag aaaaaattag ggaaatacgc aaaaggtttg ccaggatttt
    22201 agttttaaac tgaaggagta atgaatatgc aatatccaga accaattgcg aaactgatcg
    22261 acagctacat gaaacttcca ggaatcggtc agaaaacagc gacaagactc gccttttata
    22321 cgatcgatat gaaagatgaa gtagtaaatg aatttgctaa atctttgtta agtgtaaaac
    22381 gcgatttgca tttttgtagt atctgcggaa acatcacaga agaagatccc tgcgaaatat
    22441 gtagaaatcc ttcacgtgat cgaagcgtta tcctagtggt cgaagagccg aaagatgtaa
    22501 tggcaatgga aaaaatgcga gaatatcacg gactttatca tgttctccat ggtgtgttat
    22561 caccgatgga agggacaggt ccagaagaca tcaatatttc ttctctgttg cagcggctgc
    22621 atgatgcaga tgtaaaagaa gtgattatcg caacaaatgc aacaacagag ggagaagcaa
    22681 cagctatgta tctctcacgt ctgatcaaac ccgcaggtat caaagtgact cgtctagcac
    22741 atggtctgtc tgtaggctct gatatcgagt atgcagatga agttacttta ttgaaagctg
    22801 tcgaaggaag acgtgagtta taaatttcta attaagtgtt ttttcagata caatataaaa
    22861 gcagcacaag agatgggggc aacaatgtga acggactatt tattacaatc gaggggcctg
    22921 atggtgcagg aaaaaccagc atcttgaatg aactttaccc tcttttgaaa gaagtagcaa
    22981 aaacagaaat cattcaaaca agagaaccag gaggcattcc gattgctgaa gagatccgag
    23041 cagtgatcct tgatccaaaa aatgatcgga tggatgaacg tacggaagca ctgctttatg
    23101 cagcagcaag aagacaacat ctagtcgaaa aggttctgcc tgctctggca aaagggaaaa
    23161 tcgttttatg cgatagattt gtcgacagtt ctcttgctta tcaaggtgca ggccgacgca
    23221 tcggcgttac cgagattgct cggttgaatg agtttgctac agaaggtact acgccggatt
    23281 ttacccttta tcttgacgta gattcagaca ccggattaag aagaatcaag aaaaacagac
    23341 aaaatcaaat cgaccgttta gattcggaag gtttggaatt ccaccagcgt gtacgtcatg
    23401 cttacttaaa gctggcagaa gagaatccgg aaagaatcca caaagttgat gcaagaaaaa
    23461 gctttgaaga agtgctgcaa acaagttatc atacaattat tgaacagtat ccgcaatttt
    23521 ttgaaaacta ggaaggtgaa cgtttatgaa aattatttta gcgattatcc aagacaaaga
    23581 cagcaaccgt ttatcaaatg aattgattga tgcaaatatc cgtgccacaa aactatcatc
    23641 gacaggcggc ttccttaagg ctggaaacag tacgtttatc gtgggtattg aagatgaccg
    23701 tgtagaagaa gcattggaaa tcatcaaaaa aacgtgtgaa tcaagaaagc aatttgtatc
    23761 tacacctgtt acactggata tttcgatgga tgggggcgtc ccttatccag tagaagtaga
    23821 agtaggcggt gccacagtct tcgtcttacc tgttgaagga ttccatcaat tttaggagga
    23881 gctgagctat gaatcaagaa ataaacttgg ctcaaatgca accgatcgtg tatcagcagc
    23941 ttcaacggag ttttgagcat gggcgtatcg ctcatgctta tctttttgaa ggggagaaag
    24001 gaacaggaaa acatgaagta ggtatatggc ttgcacagca cctgttctgt acccaaatga
    24061 aagacaatct gccttgtgga aaatgcaaca attgtcagcg gatcgaaaag aaagaacatc
    24121 cagatgtttt ggttattgaa ccggaaggac aaaccatcaa agtcgatcag atcagacgtt
    24181 tgcagacgga attcagtcgc agcggttacg aatcaagaaa aaaagttttt ttgatcaaag
    24241 aagctgaaaa aatgaatagc agtgcggcaa acagtttgtt gaaattcttg gaagagcccc
    24301 ctggagattt tttagcggtg ttagaaacag atgcagtagg aagaattctc cctactattc
    24361 aatctcgttg tcaagttctg cattttcaag aactttcgaa agaagcactg atccatcgat
    24421 tgcaagaaga gcagattcca ttggaaaaag caaaactttt ggctttctta acaaacagtt
    24481 taggaaaagc agttgaaatc tctcaagatg aatggtttaa tgatgctaag gacttgattt
    24541 atcaatggtt cgtttacttg caaaagcaag atactcaagc ctttatctat gtccaaaaaa
    24601 aattggtaaa atcatttaaa gaaaaaacac aacagtttac aggattatct gtcttgatgt
    24661 tttattatca ggaagcacag cgtcaagcag tagcaaacgg cgaatatggc aaagtgaaac
    24721 agataaacca gataattgaa cggatattga tcgcagagca gaaactacgc agcaatgtca
    24781 gttttcaggc tgttgcggaa cagttcgttt tgcatacgat tttttagctt gccgcaaagg
    24841 atgatgatca aggaggatgg aaatggtaga agtagtaggt gtccgatata gagatgcagg
    24901 tcatatctat tattttgcac caggagactc tgaatatgtt tatagtgaca aggtattagt
    24961 cgaatctcag caatccttac atattgctac tgttgtcctt cctaaaaaag agattgatcc
    25021 caatgacctt cctgaagcta tccgtccgat cttgcataaa gcgtcacaag ctgaattaga
    25081 aaaagacaaa aaaaacaaaa aagatgctta tgatgcattg aaaatcgcaa aagaaaaagt
    25141 gcagttgcgt gagttggaaa tgaaaatggt caaagccgaa tacacatttg atcgaaataa
    25201 attgattttt tctttcacag cggacgggcg aattgacttt agagaattgg taaaagatct
    25261 ggccgctgta tttcgtactc gtattgagct tcgacaaatt ggtgtccgcg atgaagcaaa
    25321 gataataggc ggaattggtc catgtgggcg tccattatgc tgttcttctt ttttaggcga
    25381 tttcgtgcct gtatcaatca aaatggcaaa agatcaaagt ttatctttga atccaacaaa
    25441 aatttccggt ttatgcggac gcttgatgtg ctgtctgcaa tatgagagcg aagaatacga
    25501 gacagcgaaa aaagaactcc ctgactttgg aaaagtaatt gctacacctg atggtaaagg
    25561 gaaagtcgta gggttgaatc tgcttagccg tatcgttagt attcggctga ctggacggga
    25621 aaatcctgtc gaatatgaat gggatgaatt gaaagaattt atccaagtag gtgagatgaa
    25681 tggataagag atcattatac gacggattga atcaattaga atcagagttg agaaatacat
    25741 taacagaact tgttgaaatg aagcatgctt tgcatgagat cgtagaaaaa aatacaactt
    25801 tggagatgga aaatcaacgt ctgcgggaac acctgcggga attgaaccaa gttgcacaag
    25861 ctccagctga aaatgtgaag caggaacttt ctaagtctcg tatgaatctt gaaaaaattt
    25921 atgaagaagg attccatgtc tgctacgatt tatatggatc aagaagggac aatgacgagc
    25981 cttgtgcgtt ttgtctagaa gtgatctatc gcgaaagcgg tcgatgacca ataacaagag
    26041 gagactggag cggagaaata ctgctccagt ctttttatta aggagattgt gacagatgta
    26101 taatcaaaaa agtttcaagg gaaatccggt atatggggat ttatatcttg taccgacgcc
    26161 aattggaaat ttagaagata tgagctacag aagtgttcgt atgctgcaag aatccgatct
    26221 tatcgcaagt gaggatacgc gtaatacaca aaagttattg aatcattttg aaatccatac
    26281 accccaaaaa agtttacatg aacataatta taaagaacgt gtccctcaat tgattgcttt
    26341 gttaaaagaa ggaaaaacga ttgctcaagt cagtgacgca ggaatgcctt ccatcagcga
    26401 tcctggacat gagctagttt tagcctgcat aaaagaaggg atttctgtga tctctatccc
    26461 aggacctaca gctgggatga cggctttgat tgcttcaggg ctagtgcctc aaccattttt
    26521 attttatggc ttccttccac gtaagaaaaa agaacagaaa gaaacattga aaaagctaaa
    26581 agaacagaca gttacgctga ttttttatga gtcaccttat cggatcactg ctacattgac
    26641 gaatttctta gaaatttttg gaaatcgcca agtcgttttg tgtcgggaat tgacaaaggt
    26701 ccatgaagaa taccttagag gaagtacgga agagctactc gcttatatcg aagaacatcc
    26761 agtaaagggt gaatgttgtc tgcttgtaga agggaatttg ttcgaaatgc cagtgacgga
    26821 agttgatgaa gagttgggaa cgttaaagga acaagtagaa gcaaagatcg cttcaggcga
    26881 aaaaccaaat gctgctatca aagcagtagc gctgaaaaat gggctgaaaa aacaagaagt
    26941 ctaccgtcag taccatgaat tagactgaga tagtataagt tgtctataat gaaagactaa
    27001 tgaggaaatc agctactaac ttttcaaatc tcttgaacgc gaacgaatgt tcttgtataa
    27061 tgaataagag gtgaggatga tggagctgca atttccttta cataatgata catcaagaaa
    27121 aatcattcat attgatatgg atgctttttt cgcttcggtt gaagaacgag atcatcctga
    27181 gtttcgcgga catccattag taattgccag acaccccagt gacactggtg ggcgtggagt
    27241 agtgactaca gcaaattatg aagcaagaaa attcggaatt cattcagcaa tgagtgcaca
    27301 aaaagcgtat gagctttgtc cgcaagccat ctttaagcct ggcgaccatc ataaatacag
    27361 cgatatttcc aaacaagtac gggaagtatt ctatcgttat acagatattg tggaaccagt
    27421 tagtatcgat gaagcgtatc ttgatgtgac cgaaaataaa atcaattgca agtcagccat
    27481 caaaatcgcc cgaatgatcc aagcagatat ttgggagagt gtccagctaa catgttctgc
    27541 gggagtaagt tacaataagt ttttggccaa attagcatca gactatcaaa aacctagagg
    27601 aatcacggta gttgcccctc aagacgctgt gccattttta aaagctttgc caattgaaaa
    27661 atttcatggg gtagggaaga aaactgtacc tagaatgcat gagctaggga tttatacagg
    27721 aaaagaccta tatgaatgca cagaaatgat gttgattcga aattttggaa aaatgggcta
    27781 ttctctttat cgtaaagtca gaggaatcca tgattctcca gtaaacgtta caagagagcg
    27841 aaaatctgtg ggaaaagagc atacttatgg gcagccgttg caaacggaag aagcagtgct
    27901 gactcagttg cgccaactag ctgaaaaagt agaagaagca ctgagaagag tccaaaaaca
    27961 tgggaaaaca gtagttttga aggtcaggta cacggactat tctactgtga ccaaaagagt
    28021 gacattgcca gaatatatct ataaaaaaga agcactcttt tatcaagcaa gccttatatg
    28081 ggaggaaatc ttgggagtag aaaaaggaat ccgattgtta gggattactt tgacgaatct
    28141 ggacccgatg acttatgaaa acatcgtcct tccattatgg gaaaatcaag aaatataaaa
    28201 acagctttga gagttgaaac cggaaatccg ttttctctcc caaagctgtt tttatatcaa
    28261 gtcttgcttt ttgatttgtt cataggtttc tgttgcatcc gtacattttt cccaaatcac
    28321 aacttgattg gattctaaag atttttggac gtcaatgatc cgctggttgc tacttccgcg
    28381 aaattgtagt tttaggtcac gtttgcttaa ttcaaagcgt ccgtcaacaa ggatatcgat
    28441 ttgcgaaagg agttctaatt tatcttctga atcttgtagc aattcatcaa aggtatagcc
    28501 tgtccatgac cagatatctt ttgtcgtacc gaactctttt cggatacgtc gtacgacttg
    28561 cagacaaaca tctgtattca aaaaaggttc gccaccaagt aaagttaatc cttgcacgta
    28621 atcgttgcgc aagtcagcga tgatttgttc ttctaattca ggtgtgaatg gtttgccata
    28681 tcggaaattt tgtgcagctt tgttgaagca gccttcgcag gcaaataagc agccactaac
    28741 gtaaagactg ttgcggacac cttcaccatc gacaaaatta aacggtttgt agtcagcaat
    28801 atagttttgg ctgtagtctt ttgctaacca ttcttttggt tttggatttc tcataaaaaa
    28861 acttctttca tttaaggttc aaagatatag ctattgaaga taaaatctac tcgaccacat
    28921 aaataagaac aaactgacct aaatccattg ttcaagaaag cttgttctta ttttgataga
    28981 gggcgttcaa agatacaaag ccatcgaaag agggtggtga aaaaagactt gtcatagcct
    29041 cttattctga ataaacggtg ttcaaaagct tgcatctgca gtaataagcc caactaaacg
    29101 aaaaatatga ggaactattt ttgtttagct attcttatta cttgatgcag gacagctttt
    29161 tcacaacctc atttcatgtg tttcacacgt gaggaaattt ctttatggcg gccatgtacc
    29221 atcggacgag cttgcggatt tcctaaatag ccacaagtac gtttgactac atcacatgtt
    29281 tttggatcat gatttccaca ttctggacat tcgaaccctc gttctgtcgg tttgaaatca
    29341 ccttcgaaac cacattgata gcaatgatcg attggcgtat tcgtaccaag atacccgatt
    29401 ttgtcatatg caaaatccca tacagcttct aaagctttcg gattttgttg gagcataggg
    29461 tattcacagt agtggatgaa tccacctgaa caatattttg gataatcctt ctcaaattcc
    29521 aatttttcaa atggcgttgg gtttttacgc acatcatagt ggaaactgtt tgtataatat
    29581 tctttatctg tgatattttc gatgatgccg aatttttctg tatccaaacg gcagaaacgg
    29641 tcagttagac tttcacttgg agttgaatag acactgaaat gataaccata ttcatccccc
    29701 catgcatctg cattagcttt taattctttg acgatatcaa gtgtgaaagc ttttgcttct
    29761 gggtttgttt cccattcgcc accgaagaaa gctgaagcaa cttcatacaa tccaatgtag
    29821 cctaacgata cagtagctcg acggtttttg aataattcat tgacagaatc ggtacgtgaa
    29881 agacgtttcc cgaaagcacc atacatatat aaaattggcg catttgctgg aatggcttct
    29941 ttacaacgtt ctacacgata gagaagcgca tctttcatga tttctaagcg gtcagacagt
    30001 aactgccaga atttattctg atctcctttt gattcgatcg cgattcttgg caaattcaat
    30061 gtaacaacac ctaaattcat tcgtccgaca tttacttctt gaccattttc gtctttccac
    30121 ccttgcaaga atgaacgaca gcccataggt actttgaaac ttccagttaa ttcaacgatt
    30181 ttatcgtaat tcagaatatc aggatacatt cttttcgttg cacattccaa tgctagttgt
    30241 ttgatgtcgt aattaggatc ttcagggttt aagttcacac cttttttcaa agtgaagatc
    30301 agtttaggga agatagctgt ccgcttttca ctccctaatc cattgattcg aatctgtaaa
    30361 attgcttttt gaatttctct ttcaaaccag ttttctccta gtccaaatcc taatgaagtg
    30421 aaaggagttt gtccatttga agtaaataag gtattgattt catattccaa actttgcata
    30481 gcatcgaaga tatctttttt ggtttttgct tttgcatatt ctttttggcg ttctggcgaa
    30541 tcgatccatt cttccgcgtc ttttagatgt tttttatagt tcaattctgc aaaaggagca
    30601 agcaattcat ctgttcggtc ggcagaacag ccaccatatt gacttgacgc tacattggca
    30661 ataatctgtg agatttgtgc tgtggcggtc tggatagatt ttggcgattc gacttcggca
    30721 ttgccgattt tgaacccatt gttcagcatg cctttgaaat caatcaagca gcaattcgtc
    30781 atcggtgtat aaggatgata atccaaatca tggtaatgga tatcgccttt ttgatgcgca
    30841 tttgctatat gtggtggcaa cattttcagt ccgattgatt ttccaacgat cccggctgtc
    30901 agatctcgct gtgtattgaa aacattactg tctttatttg cgttttcgtt cacgacagtt
    30961 tggtccttgt tgattagctt ttcaatcgaa aagttgatat ctgttgcttt actgcgagca
    31021 aaatctcgtt tggtacgata attgatgtac tcttctgcta attcatattc gtttttttct
    31081 agtaatatat gttccacgat gttttgaatc tcatagattt tgacattttc agcaaaccgg
    31141 cttttgattt cttggacaac caagtctgca atcatttgaa ttttttcata agtaagtggt
    31201 gataatgagc cgtgaatttt cttttctgct ttgatcagtg cttcattgat cttttgttca
    31261 tcgaaatcaa catggcggcc atcgcgtttg atgactttca tctgggatgt ctctggctgc
    31321 tgagtaacga cagttttttc ttcataattt actttcatta tcttcaactc ctgctaaatt
    31381 gttcttgtct atcataaaac aaaatcgggg aaggagcaac taaatatcgg ctatatatag
    31441 tattcaatgt gctgtataat tggatttcta tactatatgt agtgtatatt ttattgtgaa
    31501 aaaaggtgaa aacttgtagc tggtggattt gttttttgca tatttaattt tgctgaataa
    31561 aataattgaa taaaattttt tattcagtcc aagtaaaagt gacaaaaaca taagagcaaa
    31621 ttattcgtag atatgctact atgcaaataa atagaaatga aaaatgaaag aggaggagaa
    31681 gaattggaaa agatgatcga agtgaaacat ctaagtaaaa gctacggcag caaactttct
    31741 cccgtcaaag ccttagataa tatctcattc acagtagaag aaggcgagtt tgttgggatt
    31801 atgggcccaa gtggtgcagg aaagacaacg ctgatgaata tcttgtccac gatcaatttg
    31861 cctacgatgg gcagtgtctc gatccaagga aaagaaatca caaaaatgaa aaacagtgag
    31921 ctcagtgact ttcgtcgaaa aaaactagga ttcatttttc aagagttcaa tttgatcgat
    31981 accctaaatg caaaagacaa tatcctattg cccctagcag ttgaacggat gactaaagag
    32041 gaaatggaaa agagagtaag acatgtagct caattgttga atatagaaga actgctcaaa
    32101 cggtatcccg atgaactttc tgtcggacag agacaacgaa ttgcagctgc tagagcactt
    32161 gttgttcagc cacaagtgat ttttgcagat gaaccaactg gctctttgga ctcgaagtcg
    32221 gctacagaat tgttgaacta cttgaagacc atgaatcaaa aagaaaaagc aacgatactg
    32281 ttagtcaccc atgatccata tacagcaagc tactgcgata gaattttatt tattaaagat
    32341 ggtgtgattt tttctgaagt tgtcagaaga gggacaagaa gagagttctt tgagaaagta
    32401 atagacatgc aggcgacgat tggcggagga ggaaaaatga atgctgtata aactagccgt
    32461 taaaagtttt tttcggcagt cacgaggcta tcttgtttat tttttcagtt tgactttatc
    32521 cgtaatgatc tattattcct tcagcgcaat gacctacgat caatctttag tcagaagagc
    32581 aagtcaagat acttcgatag atggtggatt gagttttggt ggatttatca ttactgttgt
    32641 tttgcttttt ttcgtattca gtgccaaccg atttttcttg aatagaaggc aaaaggaaat
    32701 aggcatctat cagctttttg gtatgaataa actgcagata tcaggtatat atgtgttaga
    32761 aatcatgata attggattgt tcgcctgtat ttctgggata ttactcggta ttattttttc
    32821 caaactcttt tcaatgattt tggttcgaat gatggatatg gatcttacta gtccattttt
    32881 tatctccatt ccatcagtag tagatacttt atttgctttt ttcatcatcc ttttagcagt
    32941 atctgtatat tcaatatgga aaatatggcg ctatccaatg attcgaagtt ttggagaaaa
    33001 agaacaagca gatagttcaa caatgcgctt caggacaagg caccgattac tcgcagtcat
    33061 cgggttacta cttttaacga gcggatattt tggagctagt cattttaggg aaatcacttc
    33121 atggatgatc agttatcatt atcttgatac attagttttc ttttttcctt ttttaatttt
    33181 tttcgtttgt gtggtcggta cttatttgtt tttctgttat acatttcggt tatttttgat
    33241 catattgagt aaatggaaga tttattacta tggtatcaat tttttgataa tgggtaacac
    33301 gcaagttcat ttgctcaaaa gttggcgtac aaattctctg attacagtca ttctcggaat
    33361 ttctttaatg acaattggcg gcacggctag tatctctact attttatcct accaggagaa
    33421 agtttcctcc ccgatggact atcagtttga tgttgagaca gagaaaaaaa tcaagccgat
    33481 tctagcagag gaagggcaga agataactaa agaaatcacc ttgcattata aagtcattgg
    33541 gagtatctat agtcaaaatc tcgaagaacc tatgtttcaa actgctaatc tgatcacgga
    33601 aacacaatat caagccttca gaaaagttaa tccagatttg ccgaacattt ctttgaaatc
    33661 acctggtcat actgttttgc ttgatcaaat gcaaactctt tttcggaata tttcattata
    33721 tggatctagt attggactgc cagataatca agaattgaag attcaacaaa tgcttccaag
    33781 tgtattaggt gacgaaacaa tggtatatct aagtcctgta ctgattgtag atgataccgt
    33841 ttttgaaaaa gcaaaaggtg tggattatca agtagtcaat gtagatgtat caggtggaaa
    33901 taatgaaaaa atagatgaac gactgagcaa tgacctgtcg ataaagtggc tcaatgctgt
    33961 ttattattct tatgatatcg taaatggaag tctacaagga gaaattagca caaagaaact
    34021 tccggatgac caaatgaagg aagcacaatt tagccaagaa agctctcgtt tgaatttctc
    34081 ttccagctat tcgaaattgc gtgcagttaa tcggcgaatc ggtatcaata tttttgtcac
    34141 actatttgtc gggatgatcg tgattattgc tactggtagt attttgacag tccggcaatt
    34201 agcagaagca gaggaagaaa aagaaaatta tcacctattg actaagctgg ggattccaca
    34261 aagaaggatc agacggatga tcttcgagca aaacgcactt accttctttc cacccatgat
    34321 attagggatc actcacgcag tatttgcaat caatgtcttc actcagtata taaaaactgc
    34381 cgattactgg ttggcttatc ttgtgagtgg cttattgatc cttatctatc ttttgcttta
    34441 tgtcattacg agtcagttat attgtcggat tatcgaggaa tgatatacgg aataagacaa
    34501 gataataaat agaactaaat tttgaatacc atttatttgg aataagaggt tgtgacacga
    34561 tttttgtcac aacctcttta ttttttatat tttttaaaag tacgagaaat tataaagaaa
    34621 aaagcagtga tttgatgtgc tatttttata aaagctatgt gacaaaactg ttagtaaaaa
    34681 aacggtttct gtaagctaga cacatgtttc tttttgtcaa aattagttac actttgtgtg
    34741 aggttatatg aggagggaat ccaatgaaca aatggcgttc taatccaaaa ttgaattatt
    34801 ggggaaaatt catcattcga acaatttttt atagtgcagt actgctgttc ctgatttatc
    34861 tgtatcacta taaaaatatt caaggaggaa cttttatcta taacgaattt taggaggaag
    34921 agtatggaaa tcaaaacgat tattgaagca atcgatgatt ggggaataaa tgaacctgat
    34981 cgagttgctt atcaggcgga tgagacgcat acttttggtg aattgaaaca agcatcagac
    35041 gcacttgctt attatttaga aaaaaaggta gaaggcgatg gaccaattgt cgtttttggc
    35101 aatttggagt ttgaaatgat tgtctcattt ctaggggttg tcaaatctgg ccatgcctat
    35161 ttgccgattg aagagcatac acccaaggag cgtatcctat cgatctttcg ggtggctaaa
    35221 ccatctatgg tcatcagtat cggggactgg atagaagata ttccttcggt tcctgtcata
    35281 acaaaaaaag aatttcaaga aatcaagaag ataccagtag gattttatcc cagaaatagc
    35341 gtaaaaggta cagaaaattt ttatattatt tttacttctg gtactactgg agaaccaaaa
    35401 ggcgtacaaa tcagtcatga taatctagtc agctttgttc aatggacgat ggaagacttt
    35461 gggatcaagc ctggtatgca tttcttagcc caagcgccat tttcttttga tttatcggta
    35521 ttttctattt atcctgcatt agtttctggc ggaatgctga agccgttaaa taaagcagtt
    35581 gttcaagact ttcgtcaatt attcgcgaca ttgccagcct tgaagttgaa tgtgtgggtt
    35641 tctactccat catttatgga tatttgcttg atggaaccta cattcaatgg agaaaatgtg
    35701 ccggaattgg acatgttttt attttgcgga gaagaattga cgaaaaaaac tgcagaaagt
    35761 ctacttgatc gattcccaaa tgcacggata tataatactt acggtccaac agaagcaact
    35821 gtagctattt caagtattca gattgaccag catgtactag atagttatga ccgactaccg
    35881 attggctacg taaaaaaaga cacgaaagtt tctattgtcc aagaaggtaa acctgtttca
    35941 aaaggagaaa cgggtgaaat cattattgca ggaccaagcg tatcaaaagg ttacctgaac
    36001 aatcccgaaa agacagctgc tgcgttcttt tgtcaaaatg acttagcaag ttaccataca
    36061 ggggatgcag gtagactaga tgaatatggg cttttatttt atgaaggacg tatggatcag
    36121 caggtcaaat tacatggata ccggattgaa ctcggggata tcgaacatta tctgctccaa
    36181 gacaaccgaa tcaaacaagc tgtcgtcgta ccaaaatacc aaggaacaaa agtacagcag
    36241 ctggttgctt ttgtcgtatt agaaaacaaa acgaaacagc cggattttca gttgactaaa
    36301 tctatcaaag aacaattact agaagttgta atggattata tgattcctca gaagttccat
    36361 tatgtcgatc tgctgcctca gacagttaat ggaaaaatcg atcgaaaaaa attaacagct
    36421 gaggtgaatc ctgaatgatg ttacctcata tgatccctta tgcagagccg ttttattttt
    36481 ttcttttagc cattgcgctt gtaccgatcg ttctatcttt attgatatgg gaaaaaagat
    36541 taccagttta tcaatcagca gtgacacttt tctttttatt tgtcagcttt ggaggtaatt
    36601 attggcaaca gggagcggcg ctgattgggt atgttttgtg gcagacgata cttgtatggg
    36661 gctattttgt ttatcggcaa aggaaaaatc agacaggatg gttttttgcc gccgttattt
    36721 tagcgataat tccactgttt ttaacgaaag tgactccttt ttttgaacat ggaaaagcat
    36781 cgttacttgg ttttttagga atctcttatt taacctttaa atctgtacaa atgatcatgg
    36841 aaataagaga tggcatgatc aaaacatata agccatttcg ttatatccag tttctgctgt
    36901 tctttccaac aatctcttct ggaccaatcg atcgctatag gagatttgaa aaagatcagc
    36961 tccatccgcc tgttcgtgat aaatatgttg atcttttggg aaaaggcgtc caaaatattt
    37021 ttgtcggttt tttatataaa ttcattatcg gttattattt tggtcaagta ctgcttcctg
    37081 tagtgggacg cattgcctta cagcatggtg gtatttcatg ggcattagta ggttatatgt
    37141 acgtgtacag tatgtatttg ttttttgatt ttgctggcta tagcttattt gcagtcggta
    37201 caagctacat gatgggatat cagacaccaa tcaatttcaa taaacctttt ttatcatgga
    37261 atatcaaaga attctggaat cgttggcata tgacgctgtc cttttggttc cgtgattatg
    37321 tatatatgcg attgatgttc ttcatgatga agaaaaaatt ttttaaaagc aagatcgtaa
    37381 tgtcaaatat cggttatttt gctttgtttc ttctaatggg tatatggcat ggattgacgt
    37441 ggtactacat cgtatatgga ctgtatcatg cttgtctgat ctgtctgaca gatgcatgga
    37501 tccgatttaa gaagaagcat aaagagcagt tgccttctaa caaatttacg catggcttag
    37561 ccgtattttt gacatttcaa gcagtatgtt ttagcttcct gattttttca ggatttttag
    37621 ataaactttt ttttagctaa cgaatagtga catattaatt tatataacaa aggagaaaag
    37681 gaaaatggaa gaacaaattt tatcaatctt agaagaaata acaggaacag atgaagtaag
    37741 aaaaaatcgt gatattgatc tatttgatga agggttgctt gattctttag catctgttca
    37801 attattagtc gagctagacg gagagctgga tatccaagtc cctgtatctg aattcgagcg
    37861 agaggattgg agcacaccga ataaaatcat tcaacaagca actgcattga agggttgagt
    37921 atgaaaaaga aactttttgc tattttcggc ccggttgttt tagctgttgg cttactgttt
    37981 gtgtttttta cctcctccta tcaagtagat atctctaatc cagaaacgat tagacgtgcc
    38041 tcttcttcca tgtcagtgaa cgtgttgaaa ggagatgcga taaaaaatta tgcattatct
    38101 gaaaaacaat atattccttt ttttggctca agtgaattaa gcagaatcag tccatttcat
    38161 ccgtctgttc tggcagaaaa ataccagcga aactatcgtc catttttgct gggagcaccc
    38221 gggacacaat cgttaagcca atatatgatg atgcgttctg caggagatgc tatgaaaaac
    38281 aagaaagtcg tctttattat ttctcctcag tggttcgtta aaaatggtgt aaaaactgat
    38341 tactttaata cgtattattc tgaacttcaa acatacgact ggttgttttc aatgaagaaa
    38401 gtaacgcctg ctgatcgcta tttagctaga agattattaa ctttctcaaa agtaaaagag
    38461 aatgatacgt tgacggcgat tctgcaaacg atcaaaaaag ggaagctacc tttacctgaa
    38521 tctttgaatc agctgcgcag ccaatggaac atgctgaaga gagaggatga agtattcagc
    38581 aatattgggt tgaaagatcg acagcaaaaa atcgatcatg agtcaaaacg attaccaaaa
    38641 caataccaag aaacagaatt atccatttta gcaaatcaaa ttggagaacg agaaacgacg
    38701 aataatccat tcgggttgaa aaacgatttt tatacgcatc gtatccgagc ccacgagcca
    38761 gagctcaaac agtcacaaaa aaattgggat tatcgttttt cgccagaatt ttctgatttt
    38821 cagctggtct tggatcaatt agcaaaaaac cataacgaag tattgttcat catcccaccg
    38881 gttaacgaga aatggagcga ttataccgga ctatctcaag aaatgttaca aggatttgcc
    38941 aaaaagatca aatttcaatt aaatagccaa ggattcaatc gaatagctga ttttgtcaat
    39001 caagcgggta ccaactattt tatggaagac acgatccatc taggctggaa aggctggttg
    39061 gctgcagatc aacagatcag accgttttta gaagaaaatc atattactgc tagtaagtat
    39121 catcttgacg atgctttttt tagcaaatct tggcaacatc aaataccaga taaactacaa
    39181 ttaaaataaa gaaaacaggc gagtgttgct cgcttgtttt ctttattttt gaatattctg
    39241 aataaaagat aaaaatacca agtttgcctg aacaaaaatc ataagcaatg gtataatcac
    39301 aatatgaata tagaaatggg ggaaaacatt tggatacaaa agaagaacag ctacttattg
    39361 atttaacttc tgcaaaagga gtacctggaa atgaagaaga ggtaagagaa gtattcagag
    39421 aatatgccaa accattcgct gatgatattt tttatgacgg tttaggcagt gtgattgcca
    39481 aacatggtgc tggcggaggc cccaaggtct ttatttctgg acatatggac gaagttggtt
    39541 ttatggtaac aaaaataacc gaaaaaggat tcttggaatt ccaaactctt ggaggttggt
    39601 gggggcaagt catgcttgct cagcaagttg aaatcaaaac acgtgaaggg aaaatcgtcc
    39661 acggtgtgat tggttccaaa ccaccacatg ttttaacacc tcaagtaaga aataaacctt
    39721 atgaaataaa ggatatgttc attgatattg gcgcatcaag ccaagaagaa gccaaagagt
    39781 ggggcatacg tcctggagat atggtcactc catatattga atacaaacga atgaatggca
    39841 gtaaatattt actggcaaaa gcatgggata atcgtatcgg gacagctgtt tctctgcgag
    39901 tattagagaa tctatctaaa gaagcacacc caaatgtttt attcgcagga agcgatgtgc
    39961 aagaagaagt aggcttgcga ggtgctcgaa caagtacaca ccttgtaaat cccgatattg
    40021 cttttgcttt agatactggt acagcaggag acactccagg aatgacacca aaagaagcag
    40081 attcgatttt aggaaaaggc ccacagattt tgatttttga tgcatctatg atcccgcata
    40141 aaaaattatt gaattttgtt attgatgtag cagaggaaat ggatattcca ttccaatata
    40201 cagtgatttc tggcggagga actgatgcag gacaaatgca tttgacaaga gatggtgttc
    40261 cgtctgtagc cattaccgtt cctgttcgtt atctgcattc ccatacatca gtgattcatg
    40321 aagatgatta tttgaataca gtgaaactag tcacagaatt agtgaaacgg cttgatagtg
    40381 aaacagttga aaaaattcgg agttatgaat aatgaataat agaataccta tttctgaata
    40441 tcggaaaaaa gcacgagttt ctttggaaaa tcaatgggga atcaatactt ggcttgtttt
    40501 cttatctata atatttacga gcgtcatcca gaactttttt gacggtttca gtccttttcc
    40561 ggaagaaagc atgcagcagc acttattgag ttttctagtc gataatttac ttttattcgc
    40621 attcaactat gcattgtttt acattgcgct agtagttgta cggggtggca gaccaaaaag
    40681 taacctttta ttttcagttt tccaaagaaa gtattttggt tcgatacttg gcatcaattt
    40741 gatcaattca gtcatcaact ggctactcaa cagtttaatc tttctgccca tgtttttaat
    40801 cagcggagtg agtacttata tgcagctgct tttcagttca aatgcggtac ctacgggtgt
    40861 catgccagaa gattttcttg atatcagctt tgttttatcg atgataggga tgatttttgt
    40921 ttcagcactc atcatgagta ttgttggcgg tttattccaa tttgctgcat ggacaaagtt
    40981 cgactatcct gatttgtcgg ttattcaatg tttgaaatat ggctggtttt tattgaaaga
    41041 tagaattggt acgtatattt tgttgcagct gtcttttatc ggctggtatt tgctaggagc
    41101 aatcgctttg ttcatcggtc ttttgtgggt cattgtttat gtgaatgtgt cagttgcaga
    41161 attttatgaa caagcacgga ttgaaaaagg aggtccagac gcctatttta cttagcatgt
    41221 aagcagttta ttcatcaaaa aaataacttt tgtggtagga taaatctttg agggggaatg
    41281 tacgatgaaa ttaactgttt taggatgctt aggagcgtat ccttataaaa atcaagggac
    41341 aacaggttat ttgcttcaat ctgacgggtt caatttgttg atcgatgcag gtagtgctac
    41401 gctgatcaaa ttacaagaac accttgatcc acttgatcta gatgctgtga tccttagcca
    41461 ttatcatcat gatcatattg ctgaccttgg tgtattacag tattactggc aacttcatcc
    41521 taagagaaat ccggagacat tgctttcaat ttatggacac acaaaagatt ccattcactt
    41581 tgaagaattg acgttggaaa atgtctcaaa aggacatcct tattttgaag ctgaagaatt
    41641 aaaaattggt ccttttctga ttacttttat ggaaacaatc catccagtag tatgttacgc
    41701 catgcgtatc gtagaagaaa caacggggaa agtattcgta tttacaggtg attcaggtta
    41761 tttggaaagt ttcgctgatt ttgcgaaaga tgctgatttg tttctagcag atacctatct
    41821 ttttgaagga aatgaacatc atcatgccca tttcacttca aaagaagctg gagaacttgc
    41881 gaaatcagct aacgtaaaga aacttgtact tacacaccta cctcagtttg gtgatttaga
    41941 acaattgaaa aatgaagcgc aaaaggcagc aggcaaaggg attgatatag aacttgctgc
    42001 agttgacaaa gtgtttaaca tttaggagga agaacatgat ttttgtacca aatgaaaacc
    42061 acgacccaag aatcaattta gcaattgaac aatatttgct gcaagaaatg cctttagatg
    42121 aacctatttt gctcttttat atcaatgaac cttcaatcat catcggcaga aaccaaaata
    42181 cgcttgaaga aatcaatcga gattatgtgg aagaaaatgg cattcatgtt gtccgtcgct
    42241 taagtggagg cggagctgtc taccatgatt ttggaaacct gaactttagt tttatcatgc
    42301 ctgatgatgg ggattcattc cgtgactttg cgaaagtaac acagccaatc atccaagcac
    42361 ttcatgaatt gggtgttgct ggggcggaat tgaaaggccg aaatgatcta gtcattgatg
    42421 gcatgaaatt ttctggcaac gcgatgtatg ctaccaacgg tcggatgttt gctcatggaa
    42481 caattatgtt cgactctgat atcaatgaag tagtcaatgc attaaaagta aaaaaagaca
    42541 aaatcgaatc aaaaggaatc aaatcgatcc gttctcgtgt aacgaatatc aaaccatttc
    42601 ttccagaaga aaagcaaaaa atgacaacag aagaatttcg tcaagaaatc ttgttgaaaa
    42661 ttttcggcgt agagtcagta gaagaagtaa aaacgtacga attgactgat gaagattgga
    42721 aaaaaatcaa tcgaatctct gaggaatatt atcgaaattg ggattggaat tacgggaagt
    42781 ctccagattt caatttctct cgccaaaaac gtttttctat cggttcgatt gaagtccatt
    42841 tgaatgtctc agaaggaatg atcaaagaag caaaaatctt tggcgatttc ttcggactag
    42901 gagatatctc tgacgtggaa aaaaaattgg ttggacagaa atatgataaa gcatctctat
    42961 caaaaatagt cagccaaatt gatgtgaaga aatattttgg tgcgatagaa ccagaagaat
    43021 tgcttacctt actttattga aaataaaaaa tagcggaatc cacatatatg gattccgcta
    43081 ttttttatac aggattcggg taatttcgag agagttgaac agtgatccga tcaatgaaag
    43141 tatctttttc ctgcgttagt gttcctgtgt aacgatccgc tacgtctttc atcatcatta
    43201 agtcaaaacg ttcctgatca tctaattctt ctgtgatgcc tcgactaaat aggtttgtat
    43261 cgtaatgtgc actatgttcg caacaaatga cgaaatgttc ctcttgttcg tgtatcgaca
    43321 aataaatttt tcgatacagt ggattttcga tggcatgagt ttctctaaag gaatgctcta
    43381 aagcgtggat caaaagttga gccagatcgt catcgttgat aggaagttct tcgggaagat
    43441 ctgcttggaa ggttatctga atattccgtt tggcagctaa cttctggtaa cgcgctaaga
    43501 taagatttgt cacctggtgg ttgcaaaaag aacacagcat ttcgaaattt tttgcttctt
    43561 ctaatatctt ttccacatag tttttagctt ttgtttggtc cgtatgcatt aaatcttgca
    43621 gattctccat ctcttggaca aattccaggc gaagtgtatt tacttcttgg atatgctgtc
    43681 gaagctgctc ataatgttgc tccaacaaat catttttgat ttttaagaaa tctacttgtc
    43741 tccgatcttt gtcggtattt aagatgtgat cgattagatt gtagctgata ataacgatta
    43801 gaatgataat atataaaatc gtagaccaat tgatcgttgt ttgatagata cctaatgccg
    43861 tttggatgta aatcaagcaa tggataatgg ctaccaagac gatccaaggt gtacaagcta
    43921 cataaaaacg gttattctta tatgcttcgc caatgcatgc aagtgaagtg actaaagtgc
    43981 ttataacact agcaatatta gcaatcggca ttaattcagg aagttctgca ggagtaaaag
    44041 ttgcataaag cagaacgccg ataaaaatca aaagttggaa cgtacaaaaa attccgtacc
    44101 attttttata gtaaaacatt cggctccaat agtagcagat gatgaaagct gacgttaaga
    44161 taataaataa atgagataaa aaagaatgaa cgaatggttc aaaaagaata ccacttaaaa
    44221 tatcttctga tacagcttca aatcctaatg ccaaagcaaa gcaacttaag agaataagtg
    44281 agtattcaag acgtttttgt ttatacatca agtagatcgt atagaaaaag gtccctatag
    44341 cgataaaaac agcgattatc atcgtcaata cttgcggcac tgattgtgaa taaataaaac
    44401 taatcaatgg tccagttgtt cctagataaa ctttcggtgg cagtccagca tagttctgat
    44461 aaggagatga gactgtaagg gtcaattttt ttccgatata atttgctggt aaatctatca
    44521 cagccaatga gagtccggga ttgctttctt cctgataatc tttccgttgg tataaaatct
    44581 tttcgcctag atatacagta atccattgat ggtttccttt gattagtaaa tttgcttcgt
    44641 ccaacggttt ttcaagtgtc gtttccataa tgaatgtttc gtctttatcc acggtaggaa
    44701 tcgtacgagt gtacttgctg tcaaacttaa aatcaggatc atcttttgta tagaaaaccc
    44761 acgaatcttt tatttctttc atttgattgc tgtccgcagg agaaaaaata aaataaaaga
    44821 aataagcaat tcctgttaaa aataacaatg ataatataat gattatgctc cactttatac
    44881 gtaaataaaa agattctttt ttattatata tgttattaaa aaaagacata aaggtattcc
    44941 tttctaaaac ttgtaatgtt agggtaaacg ttttttaaac taacgtcaat tatttataat
    45001 aaaaaatgag ataaagatga ggaaatagaa ttagaaacat ataattatta aagggaaaca
    45061 tttttacagc tataatttga aaaaaattta tcgttattat atgattaaga aggattgaat
    45121 aaagaaagaa gttgaaaacg atacctgatt acaaaaaaat aacttttata agttctataa
    45181 cgttgattat atttttaatt cttattcttc tcgtcgtctt ggttccccga atttttggtt
    45241 tgactcctta tattattgag gacaaagaaa tgagtccata ttatgcacaa ggaaatctga
    45301 tatatgtacg accgaaaaat acaaatgaga ttttagtcgg agatattatt acatattatg
    45361 aaaattcagg aaaaaaaatc tcgacgcgtc gcgtaatagc cgttgaaaac aaccacgaag
    45421 atttttatac aaaagctgat acaaagactt atattgagcc tggagtagta aaaaagagaa
    45481 atattatcgg tagtcccatc tttcagattc catatattgg actagtcctt tcaaaaacgg
    45541 catttgcatg gattcagggg ttattcttta cgattgcttt ttgcctaaca ggaatcacag
    45601 catggaatac ctttgtagag ttgaaaaaga agcggagacg aacacagaaa tttttgtaag
    45661 aatgttaaaa acataaatgt attccagaga tccaacgact cttctgaaca tgaaacacga
    45721 gaaaacactc atgcagcttg tagatttagt cagttgttcg tataatgtgt gaagaggagg
    45781 agtagtatgc gcaatgaaat gatgcatcgt cctgtagtca aagaagaact attggatttt
    45841 atgcgtaccc agcaaaaaag attaccgggt gagctaggca aactggaaga agaagctcat
    45901 gtagcagaag taccagttat tccccatgaa acagttgtat ttttgaaatt tttacttgga
    45961 cagcttcagc ctgaacgaat cttggagatc ggagcagcta tcggtttttc atcaagtgtc
    46021 atggccacga caatcggaga aaacgctcat gttacgacaa ttgatcgttt cgatgtcatg
    46081 atcgagaaag ctaaaaaaaa ctatgaacgt ctaggactga cagataaagt gactttgctt
    46141 gaaggtcaag cagcagatat cttgccggag ttgtctggtc cgtatgactt tatttttatg
    46201 gatagtgcaa aatcaaaata tattgaattt ttacctgaat gcttacgttt gttaagaaaa
    46261 ggtggcgttt tgatggtaga tgacatcttc caaggaggaa cgatcttgct cccagatgaa
    46321 gagattcccc gtggcaaacg agctatccat cgtaaattaa atgaatttct tcgtgttgtg
    46381 atggatcatc ccgatttgac atcgacaatc ttgccattag gtgatggtgt gatcttaatg
    46441 acaaaggaat cagaaacaat cgagttgtga tacatgatta tggcagcctg tagataatcg
    46501 attgaatcga gggctcaatt cgaacttgat gtaaaagttt ctatatttgt aagtcaatta
    46561 aaggatacag gaaatctaaa taaacaggag tagcatgaag tcaatgtagc tcctgttttc
    46621 aattgataac cttagaacag ctgaaggaga atgtctcgtt ttaaaagatt gatttagtag
    46681 ttgggccaaa ataattcatt atttgctaat taaataacta tttcgtattg acagaagcaa
    46741 tttaattatc tataattatt gatgttccgc tgattcttgt catagtagct cagctggata
    46801 gagcatccgc cttctaagcg gacggtcggg ggttcgaatc cctcctgtga cgctaaaaaa
    46861 ccgttagaaa ctgaggtttc taacggtttt tctttgtttt ttgtgccaat attgtttgtt
    46921 ttcaaaggca aataaaataa aaaaacatcc ttatcgagta caattataag gagcaaaaaa
    46981 ataaaactca tcagaaaaga ggaagaagat atgacgatac tatctagaat tttagtgact
    47041 ctagttgcaa ttgaattttt ttatatcatg tatatcgaaa cggtgagaac tgattctgac
    47101 acgacaagta gggtttttaa aatgagtaaa gaagagttaa gcagaaaatc tgttcaaaca
    47161 ttgtttaaga accaaggagt gtacaatgga ctattaggag tgggactact ttatggagct
    47221 tatctttctt ccgcatctaa agaaatcaca agtatgctat taatatctat tttttttgtt
    47281 gcattatatg gcagtttgac tagcgatcgt tggattttac tcaaacaagg tgggctagct
    47341 ctgttggcat tgctttctat tttcttataa atatagaaaa aataagaatt tatctaacag
    47401 gaaactttgt gaaaaatatt actttatctc atgaaatatg atattctaat gaatggtatt
    47461 ttagaaaatt tcatgaaaaa ggagttagat aggtgttcaa aaattatgtt tcctcactaa
    47521 aaaaagaatt ttcaggttat gatctttcaa gatttcagaa agatcttttg gctgggatca
    47581 cagtagctgc tgtagcattg cctttagcct tggcttttgg ggtatcaagc ggagctgatg
    47641 cggccgcagg tttgattacg gctatcattg ccggtatcgt tattggcggt ttatcaggcg
    47701 gtttttatca aatatcaggt ccgacaggtg cgatggcagc tatcttgatg tctattgcgg
    47761 caacaaaggg aatgcaaggt gtattgcttg ctactttttt agcgggtcta tttttacttg
    47821 cagcaggact tttccgatta ggaacactga cttcttttat cccagcaccc gtaattacgg
    47881 ggtttacttc aggtattgct atcattattg cattaggtca gatcgataat ttatttggtg
    47941 ttcactcgga aggtacaaac gttattgaaa aactaagtag ttatcaaacg ataggatttc
    48001 cgataaacac agcctctttg atcatgggag ggctagtcat tttagggatg tttatctatc
    48061 caaaaaaatg ggcgaaacga atgcctagtt cgctgctggc tatcattttg gcaacagcag
    48121 ttatgctatt gttccattta ccagtagcaa ctgtgggtaa gattccacaa acattgatca
    48181 gtagtaatcg tttgaatatg ggagatttta gcttttctgc cttgcaacaa gtggcagttc
    48241 cagctattag cattgcttta ttaggaatga ttgaaagctt gctatgtggt gcttcggctg
    48301 gccgaatggc aaataagccc ttagatagca atcaagaatt aatggcgcaa ggaattggaa
    48361 atctgttgct tcctttcttt ggcgggattc ctgctactgc ggccatcgcc cgtacaagcg
    48421 tggccatcaa atctggtgca caaactagat tagctggtat gatacatgca gttgtcttac
    48481 tgctctccat gcttgttttt gcgccagtga tgtcacagat tccaatgcca gcacttgcag
    48541 gtgttttgat tgtgacggct tggcgtatga atgaatggga aacgatcaag gagctattta
    48601 ctaataaata ttggtcagca gttctattgt ttatccttac gatgatttgt acagttatct
    48661 ttgatttaag tattgctatc gtgatcgggg tgatcggcgg ctgtgtattt tttgttgtca
    48721 aaagcgctgc tatcacgatt tcattagaaa cgatcgattg gcaaagaatg gggctgccag
    48781 aaacggaaaa gctgaataac tggacagtag tgtatattag tggtccactg ttttttatgt
    48841 cttcagaaaa actcaaaaat aaattggaag aactaaatca tcacgatggt gtcattttct
    48901 ccatgcgagg cgtaccaagt attgatttga cggcacgtgc agtttttgat gaatttcaag
    48961 aaaaagcaga gcaaagagga caaacgatta tctatacttc cttgcagcca gaagtagaaa
    49021 aacaactttc tcacttgtgg gaacatacat tcacgcatca acatcaaaca gttgctcatg
    49081 cgttgacagc tttacatgcg aaatatactg caattagcca ttaaaacaat gaaaaagaac
    49141 agacaagact gtaaactgaa gattttatgg tcttgtctgt tctttttaat attgctgtaa
    49201 aagtgaagct agtacttgcc agtcttgatg gataacaggt acaagggagc gattgtagaa
    49261 aatagctgct ggatgaaaaa gtggaagaat tcgatagttt ttttctgacc attcgtaggc
    49321 atccttttgt tctgttaatt gtaagacagg ccctgtatag agttgaccat gatttttggt
    49381 aaccgtatat tctttgccaa gtaaacgttg aagaccaatg tttccaagtg tcgcaattaa
    49441 ttttggctgg accttcatca gttcgtaatc caatattggt gcatgcgcaa atacttcgga
    49501 acgagtaggt gtccgatttg gataaacagt ttctgactgt tgtgtccgtt tattgatccg
    49561 atgagtcacg cgatacgggc ggctccttac agcactggtg atatacacct cttctcgtgt
    49621 taagccagtt gaagaaagtg cctgcatcaa ttcttttcca gcttgaccgc taaaaggaac
    49681 atgcgtatca atctctgttt tccctggggc ttctcccacg agcatcagtt taggatgaag
    49741 aggtccttgc ccagcgataa atccttctac aggacggccg ttcattctta aagaagcttc
    49801 ttgtatcagt tcttttgggt attccattta tgctcctcct ttttctttta ttataagaat
    49861 aaaagaaaca caatgcgact attttatttg gtagaactgt gaggatagaa aagcagaagt
    49921 attgcttgaa tttttgtttt actttttgat tttaaattta gttgactaac ggttgctgtt
    49981 ctggtaagct agtactgttg taattgtgga ctccacagct acaaccgctc agaacaagta
    50041 ataagcacag catatgctgt cacttcggat ggcgagtcta agtatatcag aaggaggtgc
    50101 tttatagcat gtacgcaatt attaaaactg gtggtaaaca agtaaaagtt gaagtgggac
    50161 aagcaatcta tgttgaaaaa cttgacgttg aagcaggaga aaaagttgtt tttgacgaag
    50221 ttatcttagt aggcggagaa tctacaaaag taggcgctcc aactgttgca ggtgcaactg
    50281 ttgaaggtac tgttgaaaaa cacggcaaac aaaagaaagt cgttactttc aaatacaaac
    50341 ctaaaaaaca ttcacaccgt aaacaaggtc atcgtcaacc atatacaaaa gtggttatcg
    50401 acgcgatcaa cgcttaatag cgtttgagaa agaaggccta tatatgatca aaggaacatt
    50461 taagcgaaat gacgcaggtc agatcgtttc attcactttg accgggcatg ctgatgctgg
    50521 tccttatgga agtgatatcg tttgtgcggg tgtttctgcg ttagcgatca gcactgtcaa
    50581 cgggattgcc tcattagccg gttttgagcc gattgttgaa atgaatgaag aagaaggcgg
    50641 ttatctttat accgaagtca cttcaggaat gacacaagaa caaaacaata ttgctgagat
    50701 tctattagaa aatcttttat taggattaca atcgatagaa gctgaaaact cagaatatat
    50761 ccaaattaaa acaattaatg ataaatagga ggtgcagacc atgttgttat ctatgaatct
    50821 acaattattt gcccacaaaa aaggtggcgg ttctacatct aacggccgtg actcagaatc
    50881 aaaacgtcta ggtgctaaac gtgctgatgg acaaacagtt acaggtggat caattcttta
    50941 ccgtcaacgc ggtacaaaaa tctatccagg tgtaaacgtg ggtatcggtg gagacgacac
    51001 tttatttgca aaagttgatg gcgtagtacg tttcgaacgt aaaggccgta acaaaaaa
//
LOCUS       DAPBAF010000019        49989 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.019, whole genome shotgun sequence.
ACCESSION   DAPBAF010000019 DAPBAF010000000
VERSION     DAPBAF010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 49989)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49989)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49989
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.019"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(86..265)
                     /gene="rpmF"
                     /locus_tag="RD451_001244"
     CDS             complement(86..265)
                     /gene="rpmF"
                     /locus_tag="RD451_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HDT7566515.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(323..892)
                     /locus_tag="RD451_001245"
     CDS             complement(323..892)
                     /locus_tag="RD451_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HDT7566516.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            1078..1980
                     /locus_tag="RD451_001246"
     CDS             1078..1980
                     /locus_tag="RD451_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDT7566517.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            complement(2015..3799)
                     /gene="pyk"
                     /locus_tag="RD451_001247"
     CDS             complement(2015..3799)
                     /gene="pyk"
                     /locus_tag="RD451_001247"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HDT7566518.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(3873..4835)
                     /gene="pfkA"
                     /locus_tag="RD451_001248"
     CDS             complement(3873..4835)
                     /gene="pfkA"
                     /locus_tag="RD451_001248"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HDT7566519.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(5003..8317)
                     /gene="dnaE"
                     /locus_tag="RD451_001249"
     CDS             complement(5003..8317)
                     /gene="dnaE"
                     /locus_tag="RD451_001249"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HDT7566520.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KGQLIYLLGEDNVVFK"
     gene            8548..8733
                     /locus_tag="RD451_001250"
     CDS             8548..8733
                     /locus_tag="RD451_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HDT7566521.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(8795..9991)
                     /locus_tag="RD451_001251"
     CDS             complement(8795..9991)
                     /locus_tag="RD451_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HDT7566522.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(10161..11597)
                     /locus_tag="RD451_001252"
     CDS             complement(10161..11597)
                     /locus_tag="RD451_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HDT7566523.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            11890..12699
                     /locus_tag="RD451_001253"
     CDS             11890..12699
                     /locus_tag="RD451_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDT7566524.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
     gene            complement(12885..15038)
                     /locus_tag="RD451_001254"
     CDS             complement(12885..15038)
                     /locus_tag="RD451_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HDT7566525.1"
                     /translation="MMKDFMKKILNTSWLEKIRKGAQEPKNKTFRRSHVPFRLNFLFF
                     IIFTLFVALIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKA
                     NQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKR
                     LSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGV
                     TDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLA
                     KGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSM
                     NAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEI
                     TENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRS
                     GQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFG
                     LGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYTPIQLAQ
                     YASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGF
                     HQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGPTDNPEI
                     AISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
     gene            complement(15433..16281)
                     /locus_tag="RD451_001255"
     CDS             complement(15433..16281)
                     /locus_tag="RD451_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDT7566526.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPFSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDSK"
     gene            complement(16505..18445)
                     /gene="thrS"
                     /locus_tag="RD451_001256"
     CDS             complement(16505..18445)
                     /gene="thrS"
                     /locus_tag="RD451_001256"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HDT7566527.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(18782..18961)
                     /locus_tag="RD451_001257"
     CDS             complement(18782..18961)
                     /locus_tag="RD451_001257"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HDT7566528.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(19008..20831)
                     /gene="cadA"
                     /locus_tag="RD451_001258"
     CDS             complement(19008..20831)
                     /gene="cadA"
                     /locus_tag="RD451_001258"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HDT7566529.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESAYAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            21109..23388
                     /locus_tag="RD451_001259"
     CDS             21109..23388
                     /locus_tag="RD451_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDT7566530.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(23481..24128)
                     /locus_tag="RD451_001260"
     CDS             complement(23481..24128)
                     /locus_tag="RD451_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566531.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(24307..25026)
                     /locus_tag="RD451_001261"
     CDS             complement(24307..25026)
                     /locus_tag="RD451_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDT7566532.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(25157..26308)
                     /locus_tag="RD451_001262"
     CDS             complement(25157..26308)
                     /locus_tag="RD451_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HDT7566533.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(26525..27265)
                     /locus_tag="RD451_001263"
     CDS             complement(26525..27265)
                     /locus_tag="RD451_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDT7566534.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(27269..27592)
                     /gene="rsfS"
                     /locus_tag="RD451_001264"
     CDS             complement(27269..27592)
                     /gene="rsfS"
                     /locus_tag="RD451_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HDT7566535.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(27649..28242)
                     /gene="yqeK"
                     /locus_tag="RD451_001265"
     CDS             complement(27649..28242)
                     /gene="yqeK"
                     /locus_tag="RD451_001265"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HDT7566536.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(28226..28876)
                     /locus_tag="RD451_001266"
     CDS             complement(28226..28876)
                     /locus_tag="RD451_001266"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HDT7566537.1"
                     /translation="MMNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHL
                     VMAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIEL
                     ARGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPG
                     YTTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(28886..29197)
                     /gene="yhbY"
                     /locus_tag="RD451_001267"
     CDS             complement(28886..29197)
                     /gene="yhbY"
                     /locus_tag="RD451_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HDT7566538.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(29213..30322)
                     /gene="yqeH"
                     /locus_tag="RD451_001268"
     CDS             complement(29213..30322)
                     /gene="yqeH"
                     /locus_tag="RD451_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HDT7566539.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNETQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(30319..30846)
                     /locus_tag="RD451_001269"
     CDS             complement(30319..30846)
                     /locus_tag="RD451_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HDT7566540.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(31026..31811)
                     /locus_tag="RD451_001270"
     CDS             complement(31026..31811)
                     /locus_tag="RD451_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HDT7566541.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(31804..32673)
                     /locus_tag="RD451_001271"
     CDS             complement(31804..32673)
                     /locus_tag="RD451_001271"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HDT7566542.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(32674..34053)
                     /locus_tag="RD451_001272"
     CDS             complement(32674..34053)
                     /locus_tag="RD451_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HDT7566543.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(34061..34480)
                     /gene="fabZ"
                     /locus_tag="RD451_001273"
     CDS             complement(34061..34480)
                     /gene="fabZ"
                     /locus_tag="RD451_001273"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HDT7566544.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(34505..34981)
                     /gene="accB"
                     /locus_tag="RD451_001274"
     CDS             complement(34505..34981)
                     /gene="accB"
                     /locus_tag="RD451_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HDT7566545.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVIPEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(34984..36219)
                     /gene="fabF"
                     /locus_tag="RD451_001275"
     CDS             complement(34984..36219)
                     /gene="fabF"
                     /locus_tag="RD451_001275"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HDT7566546.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(36238..36975)
                     /gene="fabG"
                     /locus_tag="RD451_001276"
     CDS             complement(36238..36975)
                     /gene="fabG"
                     /locus_tag="RD451_001276"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HDT7566547.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(36987..37904)
                     /gene="fabD"
                     /locus_tag="RD451_001277"
     CDS             complement(36987..37904)
                     /gene="fabD"
                     /locus_tag="RD451_001277"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HDT7566548.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEAAPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(38011..38235)
                     /locus_tag="RD451_001278"
     CDS             complement(38011..38235)
                     /locus_tag="RD451_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HDT7566549.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(38288..39250)
                     /locus_tag="RD451_001279"
     CDS             complement(38288..39250)
                     /locus_tag="RD451_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HDT7566550.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(39260..39700)
                     /locus_tag="RD451_001280"
     CDS             complement(39260..39700)
                     /locus_tag="RD451_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005471259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDT7566551.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
     gene            40006..40971
                     /locus_tag="RD451_001281"
     CDS             40006..40971
                     /locus_tag="RD451_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HDT7566552.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(41028..41258)
                     /locus_tag="RD451_001282"
     CDS             complement(41028..41258)
                     /locus_tag="RD451_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HDT7566553.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(41344..42231)
                     /locus_tag="RD451_001283"
     CDS             complement(41344..42231)
                     /locus_tag="RD451_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HDT7566554.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(42320..43543)
                     /locus_tag="RD451_001284"
     CDS             complement(42320..43543)
                     /locus_tag="RD451_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010706866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HDT7566555.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(43560..44606)
                     /locus_tag="RD451_001285"
     CDS             complement(43560..44606)
                     /locus_tag="RD451_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HDT7566556.1"
                     /translation="MKVLLYFESEKMLAKSGIGRALDHQKRALTEVGISYTLDEKEDY
                     DILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIGSNQLSPIVKKYLVGL
                     YQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQKFREYFKLSPD
                     QKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIRKIVKEDHPENV
                     LFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVRDIPVYNGWLED
                     SKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEELKNVYESVLNE
                     KVSSKLKKVNQVKD"
     gene            complement(44770..46497)
                     /gene="ptsP"
                     /locus_tag="RD451_001286"
     CDS             complement(44770..46497)
                     /gene="ptsP"
                     /locus_tag="RD451_001286"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HDT7566557.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDTMEEV
                     VELVHEYVK"
     gene            complement(46497..46763)
                     /locus_tag="RD451_001287"
     CDS             complement(46497..46763)
                     /locus_tag="RD451_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HDT7566558.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            47242..49476
                     /locus_tag="RD451_001288"
     CDS             47242..49476
                     /locus_tag="RD451_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDT7566559.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            49624..49944
                     /locus_tag="RD451_001289"
     CDS             49624..49944
                     /locus_tag="RD451_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HDT7566560.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
BASE COUNT        14288 a        10731 c         8734 g        16236 t
ORIGIN      
        1 tattttttat ttaccgacta caaaaaaaaa aacctcaagg ctccatggtt agccttgagg
       61 ttttacattt tctaattaaa atgtattaag cttcttttga cattacgtcc ttaccatcat
      121 agtaaccaca atttgcacat acgtgatggc tttttttcat ttcaccacag tttggacatt
      181 cgtttaaccc tttgattgtc aatttgtagt gtgtacgacg ttttgctttt ttagcttttg
      241 atgttcttct agctggtact gccattttgc tacacctcct tgtaaagtct tgtatctaaa
      301 ttagacacaa tatattccaa tcttacttgt tatcgtcgtc ttttgattta gaatcaaaaa
      361 gttcagatag ttttgcaaga cgaggatcaa ttttattctc ggcttcttcc atttttctgc
      421 gctggtattc ttcttcggaa acaacttccc aatcattgcc ttttggaagt tctgttgctg
      481 cttcctcttc ttttgtcaat acccgcattg gaatcgccaa taagatgttg tcttcaatcg
      541 actctgctaa attcaataat ggaccttcaa ttagcaaaat ctcatctgca gacatttgtt
      601 catctctact ttggaattgt tcttctgtca tgaatacttc gtctacagaa aaatccatgg
      661 gcagttcaac aggttctagt gaacgtgttg aaggaactgt caaagtcgtc tgcacagtgt
      721 aatgaacgat atagcctttc ttatcaactg agaccaaacc ttcgacttcc actggcgcaa
      781 catcaagtat taaattgtct cgcttcatga gagcggcttt caagtcgagc gtctcatgaa
      841 aagttaacgg tgtctcctgg tattttctca attccaataa agaccatttc atttttcatc
      901 actcctaagc aacaaaagca attatacagg gcaaaaagca tgttgtcaat gaaattttct
      961 tgacaccttg cagttcataa aaaaacagaa aaatctttat tagaaagcct ctgtttgcta
     1021 tcatcctcag aatcatttac aataatcatt attccattaa aggagcggat gatcttcatg
     1081 aacacgaaag atatcgaata ctatgtccaa atcgtcaaac aaaaaaattt tacgaaagtg
     1141 gctaattatt tccgtgtgag ccaacctact attacatatg cattacaacg tcttgaaaaa
     1201 gagtttgaca ccgtacttat tacaagagat cgatcgcatc acgaattaat cgtcacgcct
     1261 tctggaaagc agctgtttct ccatgcacaa accattctcc aagagatttc tactgcaaga
     1321 gctgaaatca ctcagttgca aaagaaaaag cttcgttttg gcatgcctcc tattatcggc
     1381 aatgaatact ttcctaaact gtcaagttac tttatcaagc atgaattgat gaatcaaatt
     1441 gagattaccg atggaggctc tcgggactta tacgggatga tccgacaagg gaggatcgat
     1501 ttagctgtat taggctcaac acagccaatc gtggatcaat atttagaaac agagttactt
     1561 ttggacaaac gtttcatgat cgtcgtgcca cctacacatc ctctttccaa gcaggatact
     1621 gtctctttca aagatatagc agatgaacag tttgtactat tgaacgaaca ttatgtccac
     1681 cccgcagcat tcactaagct ttctaaacaa acacatactc atccaaaagt tgtttatcaa
     1741 agcaatgact tgacgatttt aaagagtatg gtccgagaaa atgtgggtat cggttttttg
     1801 gcagagattg ctgtccatcc tgaagatcat ttagtttgcc tccctctttc agatgaagtt
     1861 cagcctcgct tcttgatttc attggcaaaa cgaacacagc agatcgtcac gcctcttcaa
     1921 gaacaagtag tccaagttat ccatgaattc gttacagcac aaaaaaacag ctcttcgtaa
     1981 aagaagagct gtttttattt tttattaagc taaattagat agctgttgtt tcgccacggt
     2041 aaacgatgcc gcgacgtgaa tcaacggtaa tcaattcacc ttctgtaatt gttgttgttg
     2101 cgcctttagc accaacgatt acaggaatat cttgtgcaat tcctacaact gcagcgtgag
     2161 aagtcaatcc gccttcttca acgataacag cagctgcttt ttcgattgca ggcatatatt
     2221 ctttgtcagt tgatggtaca actagaacca ttccgtcttt tgcttttttt acagcttctt
     2281 cagcagatga agcaataact gcatttgcaa cgacagattt ttgtccaacg ccttgagctt
     2341 ctaataattt agaaccaatc atttgaattt tcatcacgtt agttgttccg cgttcaccaa
     2401 ctggtacacc agcagtgatc aagattaaat cgccttctga tgcgaaacct aattcaacag
     2461 cttttttagc tgctagttca aacatttcat cagttgttga tggtttttca gcaactgttg
     2521 ggtaaacgcc ccagtttaac atcaaaccac gttttgtgcg ttcgtcaaaa gtaacagcca
     2581 agatatctgc atctggacga tattttgaaa tcatttttgc agtgtatcct gattcagttg
     2641 cagcaacgat tgttttcacg cctagatttt ttgcagcacg agctacagat aaaccgattg
     2701 tttcagttac atctgtttta tcgaattcgt tcaattggaa tgtacctaat tctgataatg
     2761 cattttcagc ttcttggtcg atacgtgcca ttgttgaaac agcttcaact gggtagtccc
     2821 cgtttgcaga ttcaccagat agcattgttg catctgtgcc atcaaataca gcgttagcaa
     2881 cgtcagaagc ttccgcacgt gttggacgtg ggttttcttg cattgattct aacatttgtg
     2941 tagcagtgat aactgggata ccagcagcat tacatttttt gataatgcgt ttttgaacca
     3001 ttggtactag ttcagctggg atttcaacac ccatatctcc gcgggcaatc ataacaccgt
     3061 cagaaacttt gatgatttcg tcaatgttgt cgataccttc ttgagattcg attttaggga
     3121 agatttgaac atgagtcatg tctttttctt ctaagatttc gcggatatct agaacgtctt
     3181 gtgctttacg tacaaaactt gcagcgataa agtcgatatc gttgtctaaa ccaaaacgaa
     3241 tatcgtcagc atcttttgga gtaatacctg gcaaactaat agaaacgcct ggtgcattta
     3301 cccctttacg tgatcctagc atacctgcat ttttaacttc tacgactaat tcacggtttg
     3361 cttcgtcttt ttcaatgatt tgcatatcga tcaaaccatc atcaaataaa atgtgtccgc
     3421 caacgtgaac atcgtcaaat aatcctgggt aagtaaccgc gattttttct tttgaaccta
     3481 catgttcagg atccatagag atgcgtgttt gatctcctac ttcaaatttg atgtatcctg
     3541 cacgaccaaa atcagcttct gttgtgcctt gaacagttgt acggatttca gctccttttg
     3601 tatctaaaag aataccgaca tcttttcctg tctttttaac tgcttcacgg accatagtca
     3661 tacgtgataa ttgttcttca tggtcaccat gagaaaaatt aaagcggaag acatttgccc
     3721 cagattcaat caattgagaa ataatttcta ctgagttact tgctggtcct aatgtactaa
     3781 cgattttggt ttttttcatt taaaaaactc tcccattcaa ttttgtttat ttaaagctgt
     3841 acacagctta aatagcttgg tttctttcac tcttaaaatg aaagtgaatt atttagatca
     3901 tatagtgata agtctggttt atgtttgttg ttttcaagtg tatcaatgat gtcagacgca
     3961 acgatttcgt tgtcatggat accgacacat aatccacctt ttccttcttg aagcaattcg
     4021 acagcgtaag caccgaattt acttgccaac acgcggtcgc gtgcgcttgg tgctccacca
     4081 cggacaacgt gtcccaagat agatacacgt gtatgatagt caccaaattc tgaaagtttc
     4141 tcagcgaatt catttccgcc cattacacct tcagccaaga tgatcaagca atgtttcttc
     4201 ccgcgatcgc ggccttcttg gattttttta gcaactgaag ccatatcaaa atcatgttct
     4261 gggatgatga tttcatccgc tccgccagcc acacctgacc ataaagcgat gtctcctgca
     4321 ttgcgtccca ttacttcgat aacgaatgta cgaacatgag aagtcgctgt gtcacgaata
     4381 cggtcaattg attctagtac tgtattgatt gctgtatcaa aaccgattgt gaaatcagtc
     4441 ccaggaatat cattatcgat tgttccagga atacctactg ctgggaaacc gcgttttgtc
     4501 aaagccattg cgccatgata agagccgtct cctccgataa ccactagacc ttcgattccg
     4561 aattttttca attgttcgat tccttttaat tgaccttctt cagttgcaaa ttctggataa
     4621 cgtgcagaat acaagaatgt accaccacgt tggatcttgt cacctacatc tgccacatca
     4681 agacgacgaa tatctccagc aactaaaccg gcaaaaccat aattgatccc gtatacttcc
     4741 agtccttcgt aaataccttt acgaacaacg gcacgaacag ctgcattcat tccaggtgcg
     4801 tctccgccac tggtcaaaat tccgatgcgt ttcataataa acattcacct cattaaaata
     4861 ctttatccta agtatgactt aggtttacaa ccatttttgc gttaaccacg actaacattc
     4921 taacattatt tttctcactt gtcttgattt acggataaaa aaatgaaaaa aaatgaaagc
     4981 aagtagtatt ttttaccgta agttatttga aaaccacatt atcttcgcca agcagataaa
     5041 taagttgccc ctttatactc ttgctgtcat ccacccaata agcatctgac agaactactt
     5101 ttcgttgcgt tttttcgtga tacataacta ctggtatata tcctgggtgt ttctgaaaaa
     5161 tcacttgtaa ttgtttcatt atctcgggat cttcccgttc ttctgtaata cgcaaatagc
     5221 aagtttgtga aggatactgg gcttctaact ggttaggatc agcaaagctt tctccaatta
     5281 gttgcagttc ctgattatat ttgctgattt cgctccgccc ttgaacaaag atcactcgat
     5341 caacggcaaa caaattacga tatttacgat aaagagttgg aaaaactgtg acagaaattt
     5401 ctccactact gtcggttcct tcaacaaagg ccatcagttc tccttttttt gtccgaattt
     5461 ctctaacttc cttgatcatc actaataaat tgactggttg attagggacg atatctgtaa
     5521 tcagctgaac ttgtttagct aaacgaagac gatcaaaccc ttctgcagga tgacctgaca
     5581 aataaatacc taagtactcc tcttccagct tcaagcgttc ttctagtgta tagtcagcga
     5641 cttcttcttc ttttaatgcc atgattccca gcaagtcaag acttccacca ctgtaaacga
     5701 tattttggat ttttccttcg agatcaagca tcaattgttt cctgttagga gataattcat
     5761 caaaaactcc tactgctgtc agtgattgca gtaactctaa tttcagccaa cgcttatcga
     5821 tccgtatgag gaattgatcc actgactgga acgggccatt ttgttttctt tcgtttaata
     5881 tatcttctac aaaatcacgc cgaatacctt ttatcgctgt cagtccgaat ctgatttctt
     5941 ccttattgac caactcaaaa ctggaattac tttgattaat ggacggcgag gaaagtttga
     6001 gtttattttt acgtgcttct gcaatatatt ctttcaattt tgatgtgtta tgccgaacag
     6061 aattcatcag gctggtaaag aaagcacctg gatgatgggc ttttagatac gccatttgga
     6121 atcccacgaa tgaataagca aatgcatgtg accgattgaa tccatagttt gcaaattttt
     6181 cgatatattc atatacggtc gctgctgttt tttccgaata tccctgttgt aatgctcctg
     6241 atacaaaatg cgacttttct tcatctaata cgtctttttt ctttttactc actgcccgtc
     6301 gcagaatatc tgactgccct aatgtaaatc cagccatagt cgaggcgatc tgcatgattt
     6361 gttcctgata gacgatcact ccatatgtgt ttttcaaaat cgggatcagt gaatcatctg
     6421 ggtagcgaat ggcttctttt cctttcttcc tggcaatgaa ggtatctata ttttgcatag
     6481 ggcctggtcg atacaatgca ttgactgcgg caatatcttc gatgttttct ggatctaatc
     6541 ttcgtaaaac gttccggata ccagcagatt caaattgaaa tactcctgag gtttcgcctc
     6601 gttgaaacaa gagcagcgtt tttgcatcat ttagcgggat ctcttttaat cggatctcat
     6661 acccttctac tcgcttaaca gctttcaaag taaaatcaat aatcgataag ttgcgtagtc
     6721 ctaaaaagtc cattttcaaa agaccgattg cttctacctc attcatcgta tactgggtca
     6781 gaaaagcttc atcagaaccg cgttggagcg gaactagttc aagtagattc ttatcgctga
     6841 taactacacc tgctgcgtga gtcgaaacat gtcttggcaa tccttctaaa atcactgcag
     6901 ttttgaataa aagttggttt ttttcgcttg cctgaactaa ttctactaat tgatgcgaag
     6961 ttttataagc ttgggtcaat gtgattttca attgattggg tattgctttt gaccagcggt
     7021 ttgcttcact ttgcgataaa ccaaacactc tagctgcatc tctaagaacc atttttgctg
     7081 ccattgtgcc aaatgttgcg atttgtgcca tatgatattg tccatacttt tctcgaacat
     7141 aattcaatac ttcttcacgt cgattgtcag gaatatccaa atcgatatct ggcatcgtaa
     7201 agcgttcggg gtttaaaaag cgttcgaaca gcaaatcata ttctaatgga tccacatctg
     7261 tgatttctaa cacataggct actaatgaac ccgcagcaga accacgacct gcaccggtaa
     7321 cgattttgtt tctatgagca aaagccatta catcccatac gatcaagaaa taatcatcga
     7381 atcccatttg atggatgaca gataactcgt agtccaaacg ttcttggtat tcctttgtat
     7441 agtcagtgat tcggcgttcc acttgcgaat agcataactc tcttaaatat tctccagctt
     7501 gttttccatt aggaactgga taatgcggaa gtaatttctg atggaactgg aattcaaatg
     7561 aaatcgattc agctaaacgc tgggcgccta ttacagcttg ggaaagaccc gctttttcga
     7621 atcgtttgat catttcttgt tctgaaagaa gatagacatt tgctgttagt ggtaaagatg
     7681 cagataaatt ttctaaaggt atttggcttc cctctttgat atgtttcatc acttcaagtg
     7741 caaaaagttc ttcttgttgt aaactagcga tgggatgtaa tgcacaaagc gaataatttt
     7801 cttttatcac atactgatac cattcaggca attgatcagg cgtgttttct gtcaagccga
     7861 tataaaaatt tctagtaaaa acattttcaa gtaaaaactg ccaatgaccg aaaaagttat
     7921 cctctttatt gaaagcctca gaaacagaat gatttgccgg aacaacaaac gctagatggt
     7981 cggtttctgt catttctgca agttccaatt tttcttggat catttttcgg ctggaaagtt
     8041 tcatcagctg ctgataacct atttcatctt ttgcgtacgc aagcaagcca taattttttt
     8101 cttcataagt ataactaaga tgtaatccaa tgattggctg tactccttct tctacacaaa
     8161 tacgatagaa ttcaggtgca ccgtataaga catctttatc cgttatggct aatgaagtgt
     8221 agccttgttt ttttgcttct tgtacatatt ctcgaatacg tatcgtactt tgtaaaagag
     8281 aataagaagt aattgtataa agttgtggga aaaacatctt gcattccgcc ttttttttcg
     8341 ttaaaattca ctagcgttaa aaggtttgat ccttttactt tcattaagat agcaggcgct
     8401 gaagttgatt attccacttc atttgcttgc ttgtaatctg taggaatgag ttctttcgca
     8461 agaactcaaa ttttattgag atttggtctc gtttctttac attcaaagaa aatctggtaa
     8521 aattaagata gaaaagaggt gttctttatg cgatatatcg ttacattatt ctgggctgtc
     8581 gttctaggtc aagtagtcgg ttatattggt gctgcattaa caagcggaac atatgatttt
     8641 actttgacaa caatcatttc attcattgcg ggtgtcatta tccttttgat tggtgcagtt
     8701 gcgccaagaa aagaaacctc tgcccattcg taaaaaaaca gccaagagct tgagatttct
     8761 caagctcttt tttattttct actcctcacc accattataa tctgctgcga agaactttac
     8821 gaaagttgaa taaagaaaga agaatatttg acagaacaaa caaacttgtc acaataaaaa
     8881 cagcactgta attataagca tgcgcgactg tcgatcctag catgggacct aaaacttgtc
     8941 caaagttgct aaacatctga ttgtagctat agattcggct gactccttct tgaggcgtaa
     9001 tcttactgat cagtgtattg acagaaggca tcaaagcgcc agttgaaaag cctaaaataa
     9061 agcgaagtat acctaattgg agcggtgtag tgacgaatgc cataggtaaa taacagcaaa
     9121 atgataaaat gagtcctcca attagaactt tttgattccc aatcttatcc cctagttttc
     9181 ctagtttcgg tgaagaaaag acagcggaaa caccagctat cgaaacaatc aagccgctga
     9241 caaaaaggat attttctgta cttccgctca attcacgaat atataaggtc aaaatagggc
     9301 tgatcgtagt gattcctatc tgtaaaatca aggtcgtaat gaagagaccg atcaaaatag
     9361 agagatgatc catttttgaa aaaatttctt tggtgcttat cagatctttt ttctcgattg
     9421 gatggaaatc ttctttgact aagaaaatgg tcaataccgt tgtgatcatc aacaaagccc
     9481 ctgtgatcaa gaatacattt tccataccaa accactgagc cagtgcaccg cccattgaag
     9541 gtccgatcag atttccagca atcgctccgg tagacaatgt tcctaacgcc catccgctct
     9601 tttctctagg tgcctgtgaa gcaatcatcg ctgtggcatt tggaatatat ccagacaaaa
     9661 tcccattcca aaaccgcatg atcaaaagcc aatacgcgtt tggtacaaaa gccaaagatc
     9721 ccattgttaa tgtcatccct gctgctgcac ggatcatcat gagttttcgg ccttttcgat
     9781 cagctagatt tccccagatt ggtgcaacca cggcagatgc aaaagcagtc acagagattg
     9841 ctagtcccga aaacaattcg atttgatctt ttggtgttcc tagttgctca acataaactg
     9901 gtatgaatgg cataactaaa ctaatacttg caccagtgaa aaaacagcca atccacgcaa
     9961 tcactaaatt ttttctccaa ttaatctcca tctatcatcc ctctttcgtc tcttttatca
    10021 tacctatttt cgaataaaca agcaacgatc tcgccagtaa aaagagaaaa atcccgcaaa
    10081 ggtcatttta tatgtaacgt tctttttatg taaaacaaaa agagatcaga acaaatactg
    10141 ttccaatccc ttctctttag ttaaattgtt gctagaatga tgaagttgat aatgaataaa
    10201 atatcaacga tccacaaagc aacagaaact tgattgtatt ttcctttgat tactttcaca
    10261 attgtataga aaataaatcc tgctgcaatc ccataggaaa tgctatagca caatcccata
    10321 aagatcgatg caaagaaggc cggtaaagct tcttccatat ctagccattt gatgtctgca
    10381 aaagaagcca tcatcattac tccaactaaa atcaatgctg gcgcagttgc ttgatttggt
    10441 acaatggcga tcagtggaga gaataaacta cttaatgcga atagcactgc cactactact
    10501 gaagtcaaac cagtacgtcc accggccccg atcccagctg cagattcgac ataagttgtt
    10561 gtattcgatg taccaaagat agcccccaca gaagtagcga tcgcatcggc aaatagtgct
    10621 ttatccattt ttgttttgaa cccacgacca tcttccaacg cgatctcgtc ttcttttgag
    10681 aaaatacctg tgcggcgtcc tgtaccgata aatgttccga tcgtatcgaa agtatcagat
    10741 aaactgaatg cgatgatcgt catcaatact tgaggaatct tggaagaatc actgaataaa
    10801 gattgcatgc cttcagaacc aaatgctgca ccgaaagttg ttcctaattc tttaaatgaa
    10861 ttacctaacg aattcgtttg ccaatcaatg gaacttaaat caacaacacc cataaaaata
    10921 ccaaggactg tggtcgctac gataccgata agaatagccc cacggacatt ttttacaact
    10981 aaaatggctg tcagtaccaa accaatcaca gccaataaga taggagcgtt gtcaaagttg
    11041 gctaacgcag ggacgattcc accatttatc gtaacatttg tcgcttttcc gccttcaacg
    11101 acagagctcg aaatagctga ctggtctgct gaaaaagata agaatcctgc atttttgatt
    11161 ccgacatacg caacgaaaat accgatcccg ccaccaatcg catgttgaag actttcggga
    11221 atcgcccgaa taatcatttt tcgaatattt gtgacagtaa taaaaatatt gattaatccg
    11281 caaataaaca ccattgccaa ggcttgttgc caagaataac caagcccaaa aacgaccgta
    11341 aaagtgaaaa atgcgttcaa tcccatacca ggtgcctgag catatggtac atttgcgaac
    11401 aatcccatta ccagcgtacc aataatcgat gcaatgattg tcgctagaaa tactgcttgg
    11461 aagggcatac ctgatgctga caaaatcgtc ggatttacga ataagatata actcatggca
    11521 aagaatgtcg ttactcccgc cattatttca gttgatacat ttgtattgtt tttctttaaa
    11581 ccgaaaaact tttccataaa aagttccact ccctgaattt ttttctgatg gaaaactata
    11641 ataataaaaa ataagtaaaa tagggcaaat ccatcgaaca atttcaaatt atatagacgt
    11701 ttcattcgct tttcaacgtt tttttaacaa aaaaagcgaa aataatactt aacgttcgtg
    11761 tttagcttat gtttagctat ttatatagcc ataactgtag tttttgttag gaatagctga
    11821 ttgctcttgt taattaccta aaatatgcta gactaaaaca aatgctagtt gaggaaggaa
    11881 ggacccttat tgaataaaaa attaattgcc atcgatctgg acggaactac cctcaatcaa
    11941 gattcgatga ttacatctaa aacaaaagag actctaaaaa aagcaatcaa tgccggtcat
    12001 catgtcagta ttgctacagg acgcccattc cgaatgagcc atcagtttta ccaacaatta
    12061 gaattaacaa caccgatggt taattttaac ggcgcattag tacacatccc taatcagcac
    12121 tgggatggtg aaagagaaac gttgatcaat cgtgaaatcg cttttgaaat cttatcgcaa
    12181 aaaaagcagc taaatttaga ttttatcgct gctgaaaatc gtgatacttt ttttattgac
    12241 agttttgatt tctttgatga aaaaattttt gcttcttctc gtccaggaga gaagaatttg
    12301 ctttctccta aaaatttgac gacaaatcct acatctttgc ttgtccgaac agacaaacgt
    12361 tttgcaggag ctgtatctgc tgaattaaca cgtcaatttg gcagttatgt cgatgttcgg
    12421 acatggggtg gacctactgc catcttagag attgtttcaa aaggaatcca aaaagcaaaa
    12481 ggcgtgcaag agattgctaa ctacctgtct atcgatcaaa aagacgtcat tgcctttggt
    12541 gacgagcata atgatttgga attgttggat tatgcaggtt ggggagtagc tatggctaac
    12601 ggtactgacc aactcaaagg cattgcaaat gatgtcactc ctttgagcaa tcaggaagac
    12661 ggtttagctg tttatctgga aaaactactt aaactataat agagaattag attccacaaa
    12721 aaagaggttg tgacaatttt tgtcacaacc ttttttgccg agtaaacggt gttcaaaagc
    12781 cagtttctcg gtatgaagtc aaatttaagc aaaaatgtga gaagctattt tcacaaaatt
    12841 tttcttcata ctcgaaacta agcggctttt tcacgacctc ttttttattt tgccatgaac
    12901 atatcataat acgcgtccat tatttcttta gcaatcgtca agtttatgtg gtcttgttcg
    12961 tctaataagt tcggcaagac aacactgatg gcaatttccg gattgtctgt tggtccgtat
    13021 gccacgatat tactattgac tgtcgcaata tctggatgac cttccgcaac cgtttctgca
    13081 gtccctgttt ttgcggaaag gtccattttc gcactggcta atggtttggc tgttgtgtaa
    13141 ggatcggtac catggacaac ttggtggaat ccttcacgga ggatcgccat attttctgca
    13201 gaaatattga ccgtattttc tactgttgtg ccaatttctt tcttcacttc acccaagttt
    13261 ccattttcgt cattgccata gatcgctttg actaggtgcg gctgtactcg tttcccgcca
    13321 ttagcgactg ttgaagcata ttgagctaat tggattggtg tatatgtgtc aaactgtcca
    13381 aatgccaaat cggtaaagtt acctggagca taccattctt tgccattatc cgcattgaac
    13441 ttcttcatat aatcaacaga acgtgagatc ccaggagatt cattcggcaa atcgatccca
    13501 gtcgttgtac caagaccaaa ctctttgaaa gagtctctca attgctgata agctttagct
    13561 tcttcatcta aactaggtag tcccattcca ggtgtatagt ctagtcctaa catctttaac
    13621 gccactttga tcatatacgt attagaagac aattccgatg ctttgactgc atcaagagca
    13681 acttgtccgc ttcgattaaa gacagagctt ttttctgaag caccttgcag acgaatcggc
    13741 tcatcaatca aaacttgatt tccgctgatc gcgttacttg cccagcctgc tgtcaaagta
    13801 ccagccttga ctacagaccc tggatcaaag gcgctagtaa tcgtgcctaa agcattctcg
    13861 gtgatttctt tggaaccttg ttcatgactg aaaccagtca ttgctagcac ttctcctgtc
    13921 tgaggattca tagccactgc ataagcacca ggcgaatact gtgctttgcc gttgttgatc
    13981 aatgtttgat aattcctttt caaaatttct tctacttttg attggaattc tgcattcata
    14041 gataacatta aattagaacc tttttcccca gagaagattt ctttttgatt cgaaacattt
    14101 ccttcattat caagggaaac ttcatattgg gttttggttc cttgcaggac atcttcatat
    14161 tgtttttcca aataactttg tcctacacgg tcattccgag aataaccttt tgctaggtat
    14221 ttctctgctt catctgctgg aagtccttgc ttttcagtcg tcacactgcc aagaatactt
    14281 ttcagtgaac ttgctgcatt atattctcgt gtccagtctg tgccagtcga aactcctgga
    14341 agttcagaag cgcgttctgc cacaacagct aactcttgat cagtaacacc agagtttttg
    14401 atatagacag tgtttaattc atatgcacta ttcatccgtt taaagatggt agcaattttt
    14461 aattgctcct cgtttaaatt aatctcatca gctgtgactt tattgaccat cgcactatat
    14521 tgttcgctgt tccctaattg cttttctttt gccgaaagtc tttttgtggc ttctttcaaa
    14581 tgtttgggat cagccagcca aaaatctttt ttatctctat ctgtcagatt ttcatctacc
    14641 ggaacatcga tcagcgagtt cagcttcgtt gcgatttcaa gcaaatcttt agccgtaact
    14701 tgtgttcctc tcgtatatgt gatggcctga ttcgctttat tcgtaactaa agcttttcct
    14761 gtggagtcgt agatcattcc gcgaggagta ctttcttgga ccgtaatcgt agaagtagac
    14821 ttcactcgcg cctccatctc ttcgccgttc acgatctgca aataacccaa tctagcaatc
    14881 aacgcaacaa ataacgtaaa tataatgaaa aaaagaaaat ttaagcgaaa aggaacatgg
    14941 gaccggcgaa acgttttgtt cttaggttct tgtgcacctt ttcttatttt ttctaaccaa
    15001 gaagtattta atattttttt cataaaatct ttcatcattt cctatccttc cgcctattta
    15061 cattcatgct tcattgtacc caaaaacttc ttaataaaca agaagtattt aatatttttt
    15121 tcataaaatc tttcatcatt tcctatcctt ccgcctattt acattcatgc ttcattgtac
    15181 ccaaaaactt cttaataaaa aagaaaaaat gggcggagca agaaattctt tacctaattt
    15241 caagataaaa tcaacttttt gtttcacagc aatcacttaa agttacatat ccaactattt
    15301 ttttcattaa aaaataaact tatttttgaa aattatgttt tcttaagtcg tgaaacactt
    15361 tgatggatca tttatttgtg gaaaactacg ttttgttatt ctaaaaaact tatataaaaa
    15421 atagtaaggt ttttatttcg aatccataaa atattcttgg attgcttctc gtgttttttt
    15481 cactttttcg ctaagctttt cgtttttagc catatagaaa taaaaaatga tatcgatcgt
    15541 agcaaattgg gccaaaagtg aattagttgc cgcacttcga ttcgtgattt cttttggtct
    15601 agatgtttgt acgagtacat cggctatctt gctaaacggg ttatttccaa attgcgtcaa
    15661 cgcaatgatt tcgatattca tgcttttcgc cagctcggct aatgcgacta catctgcact
    15721 tctacctgag tttgaaacaa gccaaagcac tttctttttc tcattgctga caagttgcgg
    15781 gagcaagacg tggatatctt tttcaaaaat gattggctta ccgacacgag accatttttg
    15841 cagaatatct tctactacta aagaagaggc gccaacccca tataaaaaaa cagtctctgc
    15901 cgattccaaa cactctacga ctttttggat cgtttcttct tctagaatat ctactgtttc
    15961 ttttatcgct acttgtgcat tgttaccaag tttgtttttg atagagtaaa aggactcatt
    16021 tgcttctata tcactaaaac cttcatcgat tccagtctgt agttctgttg aaatcgtgat
    16081 tttgaagtcc gtcagacttt gaaaaccgat ttttttggaa aaacgtacaa ctgtcggcgc
    16141 actcaacccg gaagcttctg ctaattcatt agctgtcatt gtagggacct tctcaatatt
    16201 accgataatg tagttggcca actttttttc tgctgaagaa taatcttcca tcatactttc
    16261 aatacgacta attacgctca taagttcctc caccctttta atgatagtct atgtaagtat
    16321 accatatcag acccttattc acggtcgtat actggataaa aaacaaaaaa acaatccgcc
    16381 caacagaata tcttatccca tcaatcccac agattctatt gagcatctgt gtctttgagg
    16441 aatacctgtt atctattgtt cggattgctt tctatctact acttttttac aggaaattta
    16501 cctattagtt ttctctgctg taatttttga cttctgcttc catagcatca ataaagatat
    16561 tcaaatcttc tacagctgtt tctttacttc cataacgacg tacgttcact gttgcatctt
    16621 ccaattcctt gtctccaaca actaattggt aagggatctt ttgtgtttga gaggcacgta
    16681 tcttatagcc cattttttca ttacgatcat caacttctac acgcaacccc ttcatttgca
    16741 aacgttcttt gatttcataa gcataatcgc catgtgcatc aacagaaaca gggatgattg
    16801 ttgcttgtat aggtgccaac catgttggaa aagcgccttt gtatacttct gttaaataag
    16861 cgacaaaacg ttccattgta gaaacaattc cgcggtggat aactactgga cgatgcgtat
    16921 tttccccgtc ttctccaaca tatgtcaaat caaagcgctc tggcaataag aagtctaatt
    16981 gtatagttga taatgtttct tctgtaccaa gagctgtttt gacttgaaca tctagttttg
    17041 gtccgtaaaa ggctgcctcg ccttctgctt caaagtaatc tagttctaat tcatccatag
    17101 cggctttcag cattgcttgg gctttttccc acattgcgtc atcatcaaaa tatttatctg
    17161 tattgtttgg atcgcgatag ctcaagcgga aacgataatc tgtaatattg aagtcagcat
    17221 atactgccac catcaattca agcgtacgtt taaattcatc tttgatttga tcaggacgaa
    17281 caaatgtatg accatcattc aacgtcattt ctcgtacacg ttgtaaacct gacaaagcac
    17341 ctgatttttc atagcgatgc atcattccta attcagcgat acgaattggt aattcacgat
    17401 aagaatggat cgtgtttttg tagaccatca tgtgatgagg gcagttcatt gggcgaagaa
    17461 caagcatttc gccatctccc atatccattg gcgggaacat gtcttcttga taatgatccc
    17521 agtgtccaga tgttttgtac aactcaacat ctcccattat tggtgtatat acatgttggt
    17581 aacctagact aacttctttg tctacgatat aacgttcgat cgtgcgtcgg attgttgccc
    17641 cttttggaag ccagaatggc aaaccagaac ctacttctgg ggaaaccatg aacaagtcaa
    17701 gttcttttcc tagtttacga tggtctcttt cttttgcttc ttcacggaga cggatatatt
    17761 ctttcaaagc tttcttgtca aaaaaggctg tcccgtatac acgttgcatc atttgattgt
    17821 ttgagtttcc acgccaataa gcacctgcca ctgataataa tttaaatact tgtatacggc
    17881 cagtggatgg aacatgtggt ccacgacaca aatcgatgaa ttcgccttgt tgataagcag
    17941 taatcacttc ttcttctggc aattcactaa tcagttctac tttgtacgga tcacttgcaa
    18001 aaatttctaa tgcttcctgt tttgaaagaa cacggcgttc gatcggcaga ttttctttga
    18061 cgattttcat catttctgct tcgattgccg gcaaatcttc tgcagttact tggttttgtc
    18121 cattatctgt atcgtagtaa aaccctgaat cgatagctgg tccaacgcca aagtggatat
    18181 ttggatagag gcgacgcatg gcttgggcca tcaaatgagc tgctgaatga cggactaagc
    18241 caagtgcatc ttcatggtct ggtgtgatga tctcaatact tgcatcttcc tcgattggac
    18301 gagtcaaatc aacgagtttt ccgttcactt taccagctaa agcttttttt gctaagcttt
    18361 ttgaaatgct ttcagcaatt gccaatgttg ttgttccaga ctcaaattct ttgactgcac
    18421 catctggaaa agtaattttt atcataatag tttcctcctt gaaatgtttt gattgatcag
    18481 atcatcaagc tgaaaaacaa aaaaatccta gcatctcttg aaaagagata ctaggacgaa
    18541 aagttcgtgg ttccacctaa tgttcaaacg caaatgcgtt cctcaagcgt tgtaacggtc
    18601 cgaccgccct tgcttcaaca agggtttcga aagtggtcat cctttggttt tctcctggaa
    18661 aagtttcagc ctagcttttc ctctcttatc gaagactctc aaattcagtt ggctttctca
    18721 tcaatcaatt atgtgtttat ttaaccacta ataaatagaa aaatcaagtg ggaaactaaa
    18781 cttatttttt ccattcccca tttacaccgt atgttccttt tttcatctca ttgatgatga
    18841 catggatgtg ttcttttggt gcctgcgtgt ttttatgaac agcttccgtg atatctttca
    18901 tcatattttc taattgttcc ggactgcgac cttctactaa ttcgacatgt acgaatggca
    18961 taatgctctc tcctctttct gatcgttctt ttttcaactc gattctatca tactatgttt
    19021 gtcttgggta ctgaatcagg aaaaatggct ggatcttttt ttgctctcaa ggcactcaaa
    19081 atagagaccg tatccacgac ttcttgcaaa acagctccga ataatgcggg gattagtccc
    19141 gtacttgcaa ttaacatcaa aaaaatacaa ataaagatgc caatcagtac agactgtttc
    19201 gctattctca tcgtatctct tgaaatcact actgcttttg ctacacgcaa gagatcatct
    19261 ttcaagatga ccgcatatgc actttcacta gcagctgtag aaccatgagc ccccattgca
    19321 ataccgatat ctgcagcagc aagtgctggt gcgtcattca cgccgtctcc taccatcgca
    19381 acaggtcttt gatctttagg gatactttct aaaatggtca gtttatcttg aggcaagcta
    19441 cgggcatgta cagaatctaa ttggactttt tctgcaatcg tttgagcaat ggcagatcca
    19501 tccccggtga tcatcatcaa atttttcaca tcaagttttc ttagctcctt gattgtcttt
    19561 gctgcttctg ggcgaatctg atccgaaaat aggatcgttc ctgcaaaaga tcgatcaatt
    19621 gttacataga ttgctgtatt ggacgtttct atttcttcag ctgaaacaaa agaggcacgt
    19681 ccaatcttta cttcatgatt attgactact gcttggattc cttgaccggt cacttctttc
    19741 agttgactaa caggatacag ttggctgttt ttcacgttgt tcactaacga acgagctaag
    19801 atatggctag attcctgttc tgcactagct gcatacagaa gtagctcttc tttttttatt
    19861 ccattgactg gctgaatcgc ctctacttcc aatatccctt tggtaagcgt tcctgtttta
    19921 tcaaaagcaa tcgtttttgt acgtgcgagc ttttcaatcg ttgttccagt ttttacaacg
    19981 atcccgtttt tacttgaacg gctcattcct gcaactaaag caatgggcgc agctagaatc
    20041 agtggacaag gtgatgccac taccagtacc tcagcaaatc gtaaagggtc ttttgagaac
    20101 caccaagaaa taccaccgat caaataagca atcaacgtga aagggactgc ataacgatca
    20161 gctaaacgga caaatcgggc aggcttttct tttgattctt cgactagttt aataatcatt
    20221 tgatactggc tgtctgcggc acgtttttca gcgatcattt ggatcgatcc gtctccattt
    20281 aaagaccctg acataatctg atctccaggt ttcttggttt ccgggcggga ctcacctgtc
    20341 aaagaagatt catcgaccga agattctcct ttggtcactc gaccatctgc gggtacaagt
    20401 tcgccaggct tgactagtaa ctggtcatca atatttattt catcgattac tatatcctgc
    20461 aattttcctt ctttgaatcg atgggcaatt cttggggtgt tatctaacaa agactgcagt
    20521 tctttacccg ctcgtttatt cgcgtaatcc tctagactat ctccgcccgt aagcatgatc
    20581 aatatcatca aactagccca gtattctttg acggctaatg ttgcaaggat tgcggtaatc
    20641 gctaatacat ctacgccata tcttcctgaa cgtaacgtct tgatcatttc caaaaacatc
    20701 aagaaggcga gaatccctcc agtaaatgcg acaatcgcaa atgcaagggc cggctggtga
    20761 aaaacaaatt cacttaataa agctatccca ccaataagca aagtaagtaa aaattttttg
    20821 aaatgtgtca ttgttttttc tcctctttta tgtgacttag agaggttagt aataaatttc
    20881 cagctgcctc tttcatctta agcatagtcc ttgactagca ctttttaaaa caataggcct
    20941 taattgaaaa caactatcac tatcagcgtt tccaaaattc atcagttcta caaacaaaaa
    21001 tattcagcaa ggattacttt ttcgattcat cagttaaaaa gtaccttttt tcgaaaaact
    21061 atgctatact tttaattcgt tatttacggc ggaaggagca aacatgcgat gaatgagaaa
    21121 caactagaac aaacgcacgt ggatgaaacg atcgaactaa tccagatcga acaaaatatg
    21181 ctggatacaa aacaacaaga attgactcag gaaatgaatc attcgacaaa agacacagct
    21241 aatcacaaga ttcgagctgg ttccaatgaa gctttttatg aatctgctgt tgaatatcgc
    21301 caacatgagc aggaattgct tttgaaatac catactcttg aagcacagca aaaacgcctg
    21361 caaacgttgt ctgtcatgaa agatagtcct tattttgccc gtatcgactt taaagaagac
    21421 cgtgaaacag aaacattata tctaggtatc gcttctttaa gagatctggc agaagaaaca
    21481 atcgttattg actggcgcgc accaattgcc aatctttatt atgaaggtga gattggtccc
    21541 gcattttatg aaactgaaac agatagaata gatgtcgatc tgcagttgaa acgacaattt
    21601 aaaatccaag aaggacgtat tttatctatg gtagatacgt cggaagtaat caatgatgac
    21661 tttttgctag agatattgga tgaatcatca agcaaccata tgaaaaacat cgtctctacg
    21721 atacaaaaag cacaaaatgc aatcattcgg gacacaacaa gtaaagtaat gctgattgaa
    21781 ggaatcgccg gaagtggaaa gacatccgct ttgcttcaac gtattgcttt tctgttgtat
    21841 cataatcgca agtggctcga ggctgaaaac gttcttctat tttcacccaa ccatttgttt
    21901 tctgattaca tctcgactgt attgccttca ttaggtgaaa gcggcgtgcc tacacagaca
    21961 ttcaaaaatt atttggtgca gctgctgcca gagttttctt tactagatga acagcaacaa
    22021 gaaagtggtt ttttgctagg ggaaaaagat ccgatacaag tgatgaaaag cggattgacc
    22081 ttagtcgatc agattgatcg ctatatccaa ggcatcacaa actacggtcc cttgttccgt
    22141 gatatgaaaa taaatggccg tacgatccta tcaaaggaat cgattcgcca atggtataaa
    22201 gaaacaaatg aacaattacc tttacatcat agactttctc tattacaaac gaagctcctg
    22261 aaaaaattag gcggtctgca aaaagacgaa acacgtcagc aatgggtcaa agatctggcg
    22321 gaagaacagc tccaagaact atacgcaaca gatccaaatc ttgaatatac agaacaaaag
    22381 gagcgttcat tacgtaaaaa actggccaac caaatcgtac gtaaaagatt ccgtcgaatc
    22441 catcgaggga tcatgaatta tcaatttgtc aatataacga aacaatatct ccactttcta
    22501 caaactgtgc cactttctct tctaacacga cataaaatca gcgagaccag gtggcaggaa
    22561 catttgacaa ctgttcgtac acacttgcgt caaagagaat tgcgtcaaga ggatgctgta
    22621 ctattctttt tactgatgcg ccgaacatat ccagtgacgg ttacacacaa agctcgctat
    22681 atctttattg atgaaatgca ggatttcgca ccatcacaag tggcattgct gcaagccttg
    22741 ttcccaaaag caaatttgac tttctgtgga gatctaaatc aaaatgtctt tggaaatgaa
    22801 acgatcgttg gatcattgga agaccttttc gtggaccgtg aagtcactcg tttccaatta
    22861 acgacaagct atcgctccac aaaagaaatc actgattttg ctaatcattt tattgtgaaa
    22921 gaacatcaag tagaaacaac agcaagaaaa ggagaccttc ctttgctcat ccaaggaaca
    22981 acagatgata tcaaattgaa ttggttagca gataccattc gaacgactca gggaaaagcc
    23041 cggtattggc gtacagcaat catagctaaa acacaagaag aatgcgaagc tctttatgct
    23101 caactgccag acgagttgaa acaacaagtc cagctgattt taaatgagag tgactttatg
    23161 aagcgttcca ttattttact tccagccttt ttagcaaaag gtctggagtt tgaccgagtt
    23221 ttcttgtggg atgtagatgc agaacatttt tcttctcagc aagacaaatt gatcctttac
    23281 accatgtgta cacgtgcgat gcatgaattg acccttttta cctccaataa tgaaagtcct
    23341 ttgttaaaca atatggatat ttcatcttat gagaaaaaag tactgtaagt aaaaagacaa
    23401 ctgctatcat taatgttagc agttgtcttt ttatttacaa taataattgc agaaaaagta
    23461 attcaatcat ttaaggtcat ttattctata tataaatcca aatctgtttc aggatatttt
    23521 aatttgacaa gcgaaataat cattttcagt tcttccatgt tttctggata ttctgggtca
    23581 aataccttgc tatgacggcc aatcccgcca ttgtcgatca atcggtaaat tcgattccat
    23641 tcaatgaatt ggtcaattga ttggaaattg ctgattggat agccgccaca atccaaaatc
    23701 tctgatacac gaaatgctag gtatgcacta tcgatcactt tatttttttt cgtgtctatc
    23761 ttctcatttc tttcgataag aattttttca ggacgatgtt tcaagctcca ctctaatagt
    23821 agaaagaaag cctccatccg atactcttct tcaaataacc gaaaggctga atcagaacga
    23881 cgaaaaagca gcggaatcag ataattttgt ctataaatca gcattggtgc gcggtccacc
    23941 atacactcta aataacggtt cagataccct gtaccgacat agtttcctaa tcgatagcct
    24001 tcaacgccga atcttgcgta tttttgcgct aattttgaac aatcagttac gttcacagct
    24061 aactcttcta ctttgcggta accgcttaag atacgttcaa aaggttctaa agtgattttt
    24121 gcttccatat tcttccccgt ccatcttcca catacttcat atcatttcac atgatactta
    24181 tgctctcatc ataccacagg ttgaattaga aaagaaaata aatcacacaa aaaagcaaga
    24241 caatctgtta gtgagattgt cttgcttttc gaaaaagact gaatactttt cgttaaaact
    24301 ggttgcttag tcttctaatg ccacattatg gaacacatgc tgtacatctt ctagatcttc
    24361 cagtgcatca atcatttttt caaatgtttc ttgatcttct ggagatagtg ttacctcgtt
    24421 ttgagggatc atttggatct cagcgattga aaaatcagtg attccttttt cttttaatgc
    24481 ttcttgtata ctatggaaat ccgctacttc accgtaaacg atgatttgtc cttcttcttc
    24541 cattacatcg cgaacatcga tgtctttttc cattaggtat tcaaggatct cgtcagcgtc
    24601 ttctcctgca aaagcaaaga ttgctgtatt gtcaaacatg taagaaaccg ctccggaaac
    24661 acccatgttc ccgccatttt tcccaaatgc tgcccgtacg tctgctgctg ttcgattcac
    24721 attgttcgtc aatgtatcaa caatcaccat tgagccgctt ggtccaaatc cttcatagcg
    24781 caattcagag tatgtttcat ctcctgcacc ttttgctttt tcgattgctc ggtcaataat
    24841 atgttttggt acattataag ttttagcgcg atcaatgacg aaacgtagtt tttggtttgc
    24901 atgcggatca ggatcacctg attttgctgc cgcgtagatt tcaatcccaa attttgcata
    24961 aatccggcta ttattagcat ctttagcagt tttctttgct acgatatttg cccatttacg
    25021 tcccatattt tcacttcgct ttctgatttg atagtttcat aacgcaaaaa cgtcctgttc
    25081 cattatactt gtgaatcacg attctgtgaa gctttttttc tttcttcctt cattcttctc
    25141 atttttagtc aattatctat actcggattg ggatttgccc gaaattctgt tccggaatat
    25201 tgcctcccaa ttgatagatt tgatcacttc taactaacag ttccgcttct tgtgcctctt
    25261 tttttccgat tcgggaataa atagaaatct cttttttttc ttttaagaat cttcttccag
    25321 catcggtaaa tccaagtagt cgaagataat ttttattttg ttggacagga atctcttgct
    25381 ttttgatatt cagcaagaca taacaagata atcgttggat ccgtgtccat gtatatcttt
    25441 ttgtttttac ctttgacaca aaatcctcaa aactatcagc agttgcagct gctgttttca
    25501 tgcgcgattc tattccttcg gtcatctgat agatatctgt cagttccagc aaagtagaag
    25561 ataacaaccg ataacgcaaa tacggccaat aagattccca agtctgcagc gaacaagttg
    25621 aaagatcttc ttctgtctga ggcggcacaa gtccagctat tctttttcct tcttctaacg
    25681 catggcgaat ggctgttgca ctggctatcc tctgatctgt gatgattttt tcatgatagc
    25741 ctgcactttt acgtcggatc ggatgtaatt ccatagggtg gacatacttg gcattttcct
    25801 ttgcataact taatcccaag atatgatttg gcgaagaaaa atcaagcgta atatcgggat
    25861 acagactgcg aaaaacctca gtcatttttt gcggataact atacgtttga tcagacagtt
    25921 cttgaaatgc ctcttctatc ctatcttgat tctcttggac aaagcgtccg aaactgctgt
    25981 aatcaaacga agtctcttct tctgttccaa aacacaaact gtcacagtcc agtgtttgca
    26041 agatttttac tgcaccttta gcaaaatagt cagctgactg aaccgcccat tcgacgggaa
    26101 gctccactac taaatccaca ccattttgta aagcttcatt cgcgcgatgc catttatcga
    26161 tgatagccgg ttcgcctctt tgcaaaaaat tcccgctcat tacagcaatg acgacctctg
    26221 ctcctgttat ttttcgtgcc atttccacat gatagcgatg tccattgtga aaaggattgt
    26281 actctacgat aatcccgcag cttttcatgc gcatcctcct tcatagttat cgataaaaaa
    26341 gaaatagaga caagtaaaaa aaggcaaaaa tcggaaaaaa tacccgaact atataaacta
    26401 ttctcgcaaa cacaatactt ctgcgacgaa aagctgcact gcaagagcaa tgcctatatc
    26461 gttcggatat ataatttatg ttgaagattt attcttttct tgttaactcg agcaggcaaa
    26521 accgctagtc tttgtatgct acaaagaacc agcgctttga tttctctgat gctgcttcgt
    26581 ctgtaaaatc agaaaatgct tcgactttcg aaaagccgct gttttccagc attcttaaat
    26641 aactttccaa tggataggta cgctcttgat gtagttcatc ttcacgaata aatcgaccag
    26701 acccttcttg ttcttcaacg aaaaaggtaa gaaaatgttc gatgctgtgt ttctcgcttc
    26761 ctggataact atcccacaaa aaagcaaaat tatccccttg ataatgatag ctatattctg
    26821 gaaaaacctc atctacttga taggtggagt gtacgtcaaa taaaaatcgg ccattttctt
    26881 ctaacgcttg atagacttca tcaaacactt gctgtacctc ttgtctattt ttcatatagc
    26941 acagcgaatc agaaaaacag gtaattgcct gatattgtcc gatttctgat aaatcgagca
    27001 tattgccttc cacaaattgg atcgatgcgt cttcttcata tgctcgctgg ctggcaatca
    27061 tcaacatctc ttctgaaagg tctaaccctg tcactttata tccatctttt gcaaaggcaa
    27121 ccgctaatgc tccagtaccg catgccagtt ccaaaatatt ttttgtgtct tcttgtaaat
    27181 gacgtttcga aaaagctaac cattgctgat aaagtgtttc gtccatcact tcatcgtaaa
    27241 tgaaagcaaa tgtttcataa gccatatgtt aatccaacca ttcactaaga tcgactagcg
    27301 gagcatctga ccatagtttt tccagattat agaaatttcg ttctggcgca tggaaaacat
    27361 gtacgatcac atctccaaga tcgatcaata cccattttcc gccttctttt ccttcaatac
    27421 gttttacttc atatttgttt tcttcttctt tatcaatgat ttcttctgta attgcgttga
    27481 tttgacgttc gctatttgct gaacagatca tgaaataatc tgccaacaag gaaacatttc
    27541 gaacgtctaa agcgataatg tcttctgccc gttttgaatc tgctgcttca atcgcaattt
    27601 ttaattgttc tttactatct atgatgattt cctcctaata tgagcagctt atttttttgc
    27661 tacccagtaa ttatatgttt cgattgtttt tggataaatc tgttgttctt gcgcaagcaa
    27721 atgggccaat gtatgttttg tttcaaatgc tacagcttcg tctagatcag cccatgcaat
    27781 ggctcgtgca tcttgtaccc caggaaaatc tcgacctggt tcaatatagt ctgctacata
    27841 aatgattttg tcaaggagac tcatcttagc agccccagtc gtatgcaccc ggattgcatg
    27901 aagaatctct gcatcggtga ttcctaattc ccgctctaca aacgaagcgc caacaagacc
    27961 atgccagatt gcattattat aattcaataa ctccggatca aaaccgtctc ttacgattac
    28021 cattttgaac tcctcatctg gtcgttcttt tgcataatca tgtgtcaatg cagcaatact
    28081 agctttttca ggagaagcac cgtatttttt ggcaagagcc acggctgttt cttctactcc
    28141 aagcacatgc ttgaagcgtt gttcgctcat tctcatctgt attttttgca tcaggttttc
    28201 tctagaataa gcagtatatt cattactata gtccatattc atacaaccct tcattttgaa
    28261 tataatcaat tactttatct ggaacaaggt agcggataga acagccttct ttgatctttt
    28321 gacgtatttt cgtggaactg atgtcgatct caggtacatc tacccaaatt acaggatatg
    28381 gagtatccgt tgtgtatcct ggtcgacgta tacccacaaa gttgaccata gaagtcagct
    28441 catcgatttt ataccatttt ggcaaatatt ctaccatatc cccaccgata ataaagtaat
    28501 aatctgtatc cggattgttt tgcgtcaatt ccttcatagt atcataggtg taacttttcc
    28561 caccacgagc taattcaatc gtttcaatct gcaaaaaagg attgtcttcc accgctaatt
    28621 ccaacatgtt gagtcgatgt tttgcatcaa tcgtctgttt ctcatcaaca tgaggtggct
    28681 gataagaagg catcaaaaat acgcggtcaa gacctaaatt ccggccagct tgttcagcca
    28741 tcactaaatg tgcaaggtga acgggattga atgttccgcc caagatccct acttgctttt
    28801 tcttctctaa gaattgaggc atttcttcag gaaataattg tgaacgaaca aatgtcttag
    28861 cttgcgtatt catcatggtc actccttata ttgcttttac ttcttttgat agcctttgat
    28921 acttttcttt tgtggaaggt ttgtataata caataacacg tccaatgatt tggacgattt
    28981 cgcaatctat ttctttttct aatacttgag ctgcttcttc tgcaatctca tctgtatttt
    29041 gaagtaacga tactttgatc agttctcttt tttctaaagc ttcttcaatt tgaacgatca
    29101 ttgctgaatt gatcccacct tttccgattt gaaaaatcgg ctgaagatga tgcgctttgc
    29161 tacgtaaaaa acgcttttgt tttcctctta aactcataat tttccttctt ccttaaatca
    29221 atgctttgcg tttcaataca tctacaccct ttggcgccca gcccgcaatt actactggcg
    29281 ctgttacagt gatccagcct agaccggcaa aaacgatgtc tgttttttct ttcacagaaa
    29341 actcaaaacg aacaagctcc ggaaatgcct cgacttcatc aggacgagga ggctgtaata
    29401 atccacctac atgtttttga taaaattcgt ctgctttttc cagtttcgtt cgatgaatat
    29461 ttacatcatt tgacacataa gcaataaatg aagcacgatt gccgctgata aaatcaaatc
    29521 ttgcaagtcc gcccaagaaa agtgtttgcc cttcattcag ctgataaact ttaggtttga
    29581 tttcttttaa cggtgcaatg atccgcaaat cttttttacc taagtagtgc gccatttgat
    29641 ggcgatggat aattcccggt gtatcaatca aaaaatgccc gtcatctaaa ggaatctcga
    29701 ttttatccaa ggtcgttcct ggaaactgcg aagttgtgat tacatcttgt actcccgctg
    29761 tatttttgat gatttgattg ataagcgtcg attttccgac atttgttact ccgacgatat
    29821 agacatcccg tccatcgcgg tattcttcga ttttttctaa tagttccgtc atctcatgag
    29881 atttcttagc actagttaat aatacatcta ctggacgaat tcctgcttcg taagcacgtt
    29941 ccttcatcca ttgtgttaat ttagtttttt tcaatgattt aggtaatata tccactttgt
    30001 tcccaactaa aagtactgga ttgtcaccga caaaacggtg tagtcctggg attagtgaac
    30061 cattgaagtc aaaaatatcc accacattga cgatcaatgc atctttttgc cctaattcat
    30121 tcagtaagcg caaaaagtcg tcatccgtca atgagacatc ttgggtctca ttataatggc
    30181 gtaatctgaa acaacgctga caatagactt ccccggaagc taaacctttt tccaaagccg
    30241 tttgcggcgt gtatcctaat tcaccgggtt tgtttgtttg tataacggca ccacagccga
    30301 tacattgtaa ttcttctgtc attcgattcc acctcgccag cccatatcag ggtgttttgc
    30361 taatagatag gccataattc ttttttccca aaaacgatta aattgtgtct tccaactatc
    30421 tgttgcgata atgggtttta caaggatgct acgtatccct gcacgattgg ctccacgtat
    30481 atcagtcata atctgatcgc ctaccattac tatctcatca tctgctaaat ccaattgttt
    30541 ctttgctatg ttgatccctc ttgctaaagg tttcattgct cgtgcaacat acaaaagatc
    30601 aaatttttca atcgctcgcg cgacacgttt tgaattattg tttgaaacaa caacaacagg
    30661 gattcctgca tttttcattt ctaaaatcca agtaagcaac tcttctgttc catctggatt
    30721 attccatgca atcaacgtat tgtctaaatc ggtcaatact gctttgatgc ctagattctt
    30781 taattgggca ggtgtaatct gatagatggc ttctaccatc catgttggtt tgtaatttga
    30841 aaacatgctg tctcctcatc tgcaaaaaat gaaggagcac ataaagtact cctcaacccc
    30901 gtattatact gcatatcagc aaaaaaaact acctctatac tcgttcgtct ttcagaaaaa
    30961 gcatttcttt acaaaatgac caaaaataaa gattgatcac agaaaaattt agaaacaaaa
    31021 aacaactaat attggcggaa cctcttgtat cgtttttcca gtaatttatg ctgatctaat
    31081 cgaacaagtt ccgtcaatct ttcaatcaac gcttttttca taatgtgtgc gactttatat
    31141 cgtggcaact gctcgccgtt gaacgtttca ggaataactc gatcaacgat tcctaactcg
    31201 cgtagttctg gcgcagtaat tttcatcaac tcagctgctt ctgcggcgcg actaccgtct
    31261 ttccacaaaa tcgacgcaaa tccttctgga gaaagcacag cataaatcgt ttcttccagc
    31321 atccagactt catccgctaa acctagagca agggcaccgc cacttccacc ttcaccaatg
    31381 atgatggcga tgatcggtac ctttaaatca gacatttcga gcagatttct ggcaatagcc
    31441 tctccttcgc cgcgctcttc tgctcctaca ccgcaatatg cacctgctgt attgatcaag
    31501 gtaatcaccg gtctattgaa cttttccgct tgtttcatca gtcgtaaagc ttttcgatag
    31561 ccttcaggat ggggagaacc aaaatttctg cggatatttt cctgcagatc ccgtcctttt
    31621 tgaataccga tcactgttac cggtttgcca tctaatcgag cgattccacc aacaatcgct
    31681 tcgtcatctg caaataaacg atcaccatgg cattcctcga aagaatcgaa gatctcttca
    31741 aaaaaatcca agcttgtcca tcgttcttta gctcttgcta actgaacgac atcatgtgct
    31801 gtcttatcca cgatctatcc atcctttctg tgtatgcaat tcaagaagcg tatggatttt
    31861 ctgtttcaat tccatgcggg gaacaatctg atcgacaaaa ccatgagata ataagaattc
    31921 agccttttgg aaatcttctg gaagttcctg cttgatcgtc tgttcgatga cgcgtcttcc
    31981 agcaaaaccg atcaagcttt ggggttctgc tagaataata tcgccttcca ttgcaaaact
    32041 ggcagttact cctccggtcg tcgggtccgt taaaacagtt agataaaaaa gaccttcatt
    32101 gctatgccgt ttgacagcag cagagatttt tgccatctgc attagagaaa agattccttc
    32161 ttgcatccgt gcgccacctg aagctgtgaa caagacgact ggaagacttt cctttgttgc
    32221 tcgttcgaat aatctggtga tcttttctcc gacaatcgtt cccatacttc ccatgataaa
    32281 attaggatcc atcactccaa taatgaaggg aatcccctga atggttgctt taccagtgag
    32341 gactgcttca tgaagtcctg ttttatcttg cattttttta attttttccg tatattcggg
    32401 aaatgctagc ggatctttgg ttacaagatc cgtatcccat tcttcaaaac ttttttcatc
    32461 aataatcaaa gctagacgct gccatgcacc gattcgaaaa gcgtatccgc aatgagggca
    32521 tactttttct tcaccgatgt ctttcgtata aaggatatgt ttgcaatttg gacactttgc
    32581 ccacatgtta tcaggaacag atggcgagtt agcaggtttg ctctctctat taggattgat
    32641 ccgaatatat ttctttttct taaacagagc catctatgcg cctcctatct ccgtttctgg
    32701 tgtccaattc ggtaaaaatt cttcttgtaa aaatgctgtg ctgtaatcac ctgctatgac
    32761 tgcaggatga ctaatcaaat ccatctgaaa ttctgcgttc gtgatgattc cttctgtgat
    32821 aaattcactt aaggctcgct gcatcttcat taatgcttca aaacgcgtat ttccatggac
    32881 gattattttt gcaatcattg aatcataata tggcgggatc gtatatcccg ggtaaactgc
    32941 actgtctact cgcagtccca tcccacctgc tggaagcagt aagttttgga tcttccctgg
    33001 agaaggagca aaatggaaag caggattttc tgcattaatc cggcattcga ttgcgtgtcc
    33061 ttggaatact acttcttctt gacacacatt caaaggctca ccggctgcta tctccacctg
    33121 tttttttact aaatcgattc ctgtgaccat ttctgttact ggatgttcca cttggattcg
    33181 agtattcatt tccatgaaat aaaaatcgcc ttcttcatcc atcagaaact cgatcgttcc
    33241 ggcattttca taattgactg ctttagctgc tcgaacagca gcgtctccta gtgcttctct
    33301 ttttgtttgt gagatcacta cagaaggaga ttcttccagt actttttgat tgttgcgttg
    33361 taaagaacaa tctcgctcgc ctaaatgaat gacatgacca aatcgatcac ctaagatctg
    33421 aacttctata tggcgagcag gataaatgat tttttccaaa tacatatcat catttccaaa
    33481 tgccgctgct gcttcttgct gagctgaaga aaaatgctgt gggagctctt cttttgattg
    33541 aactttccga atgcctttcc cgccaccacc tgcagctgct ttcagcatca ctggataacc
    33601 aattctgtct gctatttcca atgcttcttc tactgtagat aatacaccag tacttcctgg
    33661 aatgactggg acatttgctt cttgcatcaa ttgacgcgca ttgatcttat ttcccattgc
    33721 atcgatcgtt gcacttttag gaccaataaa tgtgatattg cactcttcac acatggaggc
    33781 aaatcggcta ttttcagata aaaaaccaaa tcctggatga attgcttcgg cttttgtcac
    33841 gattgcagcg ctcagtactt cctgaacatt cagatatgaa tcaacggctt ttgccgggcc
    33901 aatgcagatt gcttcatctg ctaactgtgt atgaagtgct tcggcatctg cttctgaata
    33961 tatcgctacg gtttggatcc ctagttcgcg gcatgcacga atgatacgta cagcgatttc
    34021 accgcggtta gctatcaata ctttagaaaa catatttcac ctatccaatc ataaaggtta
    34081 attccgcttc ggctactttt ttaccgtcta ctttagcgat tcctttgcct attccggctg
    34141 aagctttcac tttcaatatc tcaacttcaa ggtataaggt atctcccggt gtaactttct
    34201 tacggaattt tgctttgtcc aatccgccga aataagccgt ctttcccttg aattgttcaa
    34261 gagaaagtaa tgcaactgct cctgcttgag ccattgcttc aacaatcaat acccctggca
    34321 taacaggttc ttctggaaaa tgtccttgaa aaaagggctc attgatcgtt acatttttct
    34381 tagcaacgat ccgttctcct tcaaccattt cttccactcg atcaatcaaa agcattggat
    34441 aacgatgtgg aatgatttct tttatttctt gtatgttcat tgttttccct ctttcctgct
    34501 ttgcttattt ttgctgaatc ctaaagagtg gctgtccata ttcgacaact gactcgtttt
    34561 ctacaaggat ttctgtgatc actccgtcgg cctcactagt tatctcattc atcagtttca
    34621 tcgcttcaat aatgcagata acttctcctt tggcaacttg atcacctact tttttgaaag
    34681 ctggtttgtc gggcgctggt tgcagataaa cgattcccac gattggcgaa acaacctcga
    34741 ttccatcaaa tactgccgat tctttttctt tcattatttc tggagcagtt gttgcttgtt
    34801 caggtatgac attgactggc tccgaaactg gcaacgtttc gtttgtttga accatattca
    34861 tgcctcgact tgttttattt ttattcatat acaattcaaa ttgaccttca cgcaaatcga
    34921 attccgttag cgaggattga tcaaattgac tgactaattc tctgatttca ttgatatcca
    34981 aaattattcc tcccagcgtt tcatgcacag aaccgcatta tgtccgccaa accctaatga
    35041 attactcatt gcataagtaa aacttgcagg tttgctttcg tttttgacaa ctgtcaagtc
    35101 aatctcagga tcttgttttt ctacattgat cgtaggtggg ataaattgat gttctaatgc
    35161 cagcaaagtt gccaaggctt cgatcccgcc ggctgctccc aataaatgtc cagtcatcga
    35221 tttcgtgctg ctgacgtaag tatctctgaa attttcacct aatgcgattt ggattgcttt
    35281 tgcttctgcc tggtcattgg ctggtgtact tgttccgtga gcattgatat atccgacttg
    35341 ttccggctgt acaccagctt cttccatcgc aagcttcatt gctttagatg caccagaacc
    35401 atctggagta ggagctgtca tatggtaagc gtcacagttt gcaccgtatc caacgatttc
    35461 tccatagatt ttggcaccgc gagcttgtgc atgttctaaa gattcaagaa ctagaacgcc
    35521 tgctccttca cccatcacaa aaccattccg attttcgtca aacggaatcg aaccacgatt
    35581 aggatcagtt gattctgaga gtgctgttaa agctgcaaat ccagcaatcc ccatctcaca
    35641 aatcgttgct tctgttcctc cagcaagaat gacatcagaa tagccatgtt tgatgttacg
    35701 gaatgcttcc ccaattgaat tcgttccgct agcacaagct gttacgatag ctgtacaaat
    35761 accttttgca cctacacgca aagcaatatt tccagctgcc atgttggcaa tcgccattgg
    35821 tacgaacatt ggagaaactc gttttgcacc tttttcatgt agacgaataa cttggttttc
    35881 gattgttgga agaccaccga tcccagatcc gatgatgacg ccaaaccggt cttgattcat
    35941 tttttcttta tctaaaccgc tcatctccat tgcttctaaa gcagcgtaga ttccatagat
    36001 cgaaaacata tccattcgtt tgctatcttt tttaataaaa tatttatcgt aagggaaatc
    36061 tttgacttca cccgctaagg taatccctgt ttctgaagca tcaaatttag tgatcggtgc
    36121 gatgccattc gtcccctctt ttaagctatt caaaaagctg tctgcgtcat ttccaatagg
    36181 tgaagtgact ccatagccag taattaccac tcgattcatt tgtttgctct ccttttctta
    36241 tccgtgcatg accaatccgc catcgacatt gatgacttgt ccggtgatat atggattttg
    36301 tgctaagaaa actgctgttt gtgcaatatc ttctacttgt ccgaaacgct gcatcggaat
    36361 ttgcttttcc gcttgttcct tgactttgtc tgctaaaact tccgtcatat cagttgtgat
    36421 gaatcctggc gcaatggcat tacatgtaat gcctctagtt gcagcttctc gtgccacaga
    36481 ttttgttaat cctactacgc cagctttact agctgcataa tttgcttgac caatatttcc
    36541 aatcaaccca gatacactag agagattaat gatggcccct tctcgctgct tcatcatttt
    36601 tttcaatacg tgctgcgtca tattgaaggt tccaatcaaa ttgatatcca gacatttttt
    36661 gaaatcttct gcatccattc gcatcacaag tttgtcattt gtgattccgg cattgtttac
    36721 taacacatgg atcgatccaa gcttttcttc tgcttctttg atcatttgtc ccgctttctc
    36781 ataatcagag atgtcaccgg aaactcctac gcattttaca ccgaatgctt cgatttcttc
    36841 tatcttttct tttggaatct ctccgcgacc attcaaaatg atatttgctc cagcttttgc
    36901 aaaagctaag gccatcgctt tgccgattcc tcttgtacta cctgtgataa atacattttt
    36961 tccttttaca tccataacgt tcctccttat agtattgcta ttgtttcatc aaatgtctgc
    37021 ttattctcaa cacgcagaac tggtattgtt ttatcgattt ttttcataaa tccgcttaat
    37081 acttttccgg ggccgacttc gatgacttgt tcgatgccga ttgtttttaa cttatggata
    37141 ctctcataga aacgaacagg ttgcatgact tgctgttcaa gtagtcccgc gattgtttct
    37201 ttcttcatta tttccgttgt tgtgttgctt atgataggaa aagaaggttc agagaattga
    37261 atctgactta ggtccttcgc cagttttttt gctgccggtt ctaaaatagc tgtatgaaaa
    37321 ggcccgctga catttagagg gatcattctt ttgaaccctt tttcttttaa tagtaaaaca
    37381 gcttcgtcta ctgctttttc ttcgccacca atcacgatct gctgaggtgt attataattt
    37441 gcaggagata cgatgccgta cttgctagct tcatgacagc tttcctcgat cgtttcaatc
    37501 ggcgcattca tcactgcaac cattttcccg cttccagctg gggcagcttc tgtcatataa
    37561 gcgcctcttt ttgctactaa cgcaactgct tcagtgaagg atagcgcatt actagctact
    37621 aatgccgaat attctcctaa actcagtcct aaagctgcat ctgggatgat tccatgctcc
    37681 ttcaataagc gataatacgc gatgctgact gttagaatag ctggctgtgt atattgcgtc
    37741 tgatccaaac gttcattttc tgtaaagcaa agttcagcca tatcgtagcc gagaatctca
    37801 cttgcttcat caaatgtctg ctttacaacg gcttcttcat ataaatcttt tcccatacct
    37861 tgatattgtg caccttggcc actaaataag aatgctgttt tcatgttttt ctccaatata
    37921 tccagaatat atgtttgatt cttcctattc aaaaaggccg agacattcct atttcaggaa
    37981 atgtcccagc ccccaaccta attttaatga ttatgcagtt tgtttttcta cgtaagtcac
    38041 taaatcttga accgttttga ttccgtcttc tgtttcgatt ttcacgtcaa attcatcttc
    38101 aatttcattg atgatttgga ataaatccaa gctgtcagct tctaagtctt cttggatgtc
    38161 agtagtcaat ttgatttctt cagtttcttt tcctaattct tctgcgatga tttcttgaat
    38221 tttttcgaat accataataa tatattcctc cgatattgtt tgctttttat ttttataatt
    38281 taacagtcta caactccatg agaatacttc cccatgttaa acctccgcca tagcctgtaa
    38341 atattacttt ctgctgtttt cctaaggtga tctttccact agaaactgct tcatccaata
    38401 agatagggat gcttgcagca gatgtattcc catatttatc catattggtc aggaactttt
    38461 cttgcggcat ctttactttt cgggcaattt tctcaataat tctgaggttt gcctgatgca
    38521 aaagcagata atcaactggt ttgtctttca tgacttcttg gatattgttt gcaacgtctc
    38581 gtacggcaaa atcaaaaata tctctgccag tcatttgcaa ataatacgaa ccttctgaat
    38641 cttctgaata gaacggattt ttattttgct ggtagccagc ggtcaatgag ctacttctgg
    38701 taccgtcagc tgctaatttt tctttcagca attttttctg tggattcgct tctaagagaa
    38761 tcccacctgc tccatcgcca aacaacacag cagtcgtacg atcagaccaa tcgattagct
    38821 tagatagtgt ttcaccacca atcaccagtc ccttagttga gccgcagcgg atcatttttt
    38881 cagccatgct taacgcataa acaaatcctg agcacgcagc actgatatca aaagcgatag
    38941 catgagttgc tcccaatttc ccttgtactt gtgctgctac agatggtgtc gtgtaatcgg
    39001 gcgacattgt tgctactaaa ataaaatcca aatctttagg gtttagattt ttctgtttta
    39061 tcaatttttc cgccactaaa atgcataaat cagaagtctc ctgatttgtt acacatcttc
    39121 gttcacgaat acccgtcctt gacgaaatcc attcatcaga ggtatccatc atcttggaaa
    39181 gatcattatt agtaataatc ttttcaggaa ggacgctggc tgttgcagta atcattccaa
    39241 attgttccat taaatatcct cacttatagt cttgcaagaa gtcgtgcaag tttttcagtg
    39301 catccagcaa ggcatgctgt tcctccgtag ccattccgtc taagatgttc ttgaccattt
    39361 cacgatgaaa atgctgatgg acccgaaata gtaactttcc ttttttcgtt agtcccaact
    39421 ttacaacgcg gcggtcatct tcactgcgga tacgttcgac atagcctttt tttactaact
    39481 tgttaatagc agtggtcaag gtcccaacag taattgatag ttctttggct acttctgaag
    39541 ttgttttttt cttgtacatc ccgattgcct cgatcgtgtg catctctgtg attgacagat
    39601 ctttgaattg agattttttc agctcagact cttcgattgt caaaatatca ttgaagacac
    39661 taacaagata atcatttact gtttttaaat ctggttccat gttccaccgt ccactaatta
    39721 gtttgattat caaatctttt gatgttcaaa ctatatctta acttttttca aaatgcaacc
    39781 ttaaaagatc atttttttac tatatgagct ttttttaaga ttttactcat ttaaaacaac
    39841 tgataaatca gcatttataa tttcttttat tagaaaaatc atctatctca catattttga
    39901 ttatcaaagt attttctgtg aacagaacta tagaattccc taaaacttgt ccattatttc
    39961 aaaatttgtt atagtctttt tattcaaagc gtaaaaggag atcctatgtt aaaagaaaaa
    40021 atgaaaactc tccccatgct gccgggtgtc tatcttatga aagaccgaga tggtaaggtc
    40081 atctatgttg gtaaagcaaa acggctcaaa aatagagtaa gcagctattt tcatcagaat
    40141 aaacagcatt caaaaaaagt attacgtatg attcatcata taacagattt tgatttcgtc
    40201 gtagtagaca cggaattaga tgctttattg ctcgagtgtc aattgatcca acattaccgt
    40261 cctttttata accgacaaat gaattatttc agtaattata attatgtaca tattaccaat
    40321 aagggatttg tattaacaga tactcctacg gctcgaacat acgggccttt tcgtctctat
    40381 aaaaaaatgc cgtctatttt gcgtataatg gaagaaactt atcaaatgcc ttggttgtct
    40441 gaaattagtt tgttagcttt gcgagtccag cttcctgacc tacaggaaat gacttttgaa
    40501 cagaaaaaaa aggaactcca agggctgttt caaggccgaa ataaaaagct actgacttac
    40561 ttgaaaaaaa gacaacaaca tttcatctat cagttgaatt tcgaaaaagc cggtatgctt
    40621 caaaaagata tcgaattagt tacttatttt attagacgga tccaggaaca aaagcagttt
    40681 ttaagaacac catcgctcac cttcagcatg ccattagcag cagatgagag tcagaaaaag
    40741 cactacctcg tttgttatgg tcaacttgca gaaacaatga ttacctctgg tgacgtttct
    40801 cctgacttct attatgaaaa gaaagaagct catttatctt tgaaacgtca attgtcaaaa
    40861 gaagaaatcg atcctgtaca aatcttgatc agttaccgca aaaaattaga aaaagaacag
    40921 tttgaaattg aactgttaaa caaaaaagaa gctgaaaagc aactaaatta gttgcttctc
    40981 ggcttctttt aggcatcttc aacttcaaat gtcaattatc ctaaaattta ttggattaag
    41041 tcatagattt ccatcgctac gatatcgata ttatcaaatt cgtattgctg atgagtatct
    41101 gtttcagtta attcaaatgt atcggtcgct ttatcataag ttactgtaca cttctctacg
    41161 ccttcttttt caaaacggcg aacttgcagt tcattatctg ctgactcgac catagcctcc
    41221 agtcgtttta tgattgcgac taattgtgaa tgtgtcatcg gaggtcctcc ttttcttatt
    41281 tctgttatat tgtatcaaaa gcatagccta cttgcattga ttttctctaa aaaaactcgt
    41341 tttttatgat tttttttctg gtatttttcc ttcaggccac caaagtttga tcaaagcttg
    41401 ggttccgtca ttctcaaaac ctttatctgc caactcttca tatagtttca atgcttgggt
    41461 agttgctggc aatacaagat ccattttttc tgcttcttct aatgcaatct ttaaatcttt
    41521 gataaaatgt ttgacaaaaa aaccaggtgt gtaatcttct tttaaaatac gaggagaata
    41581 attgcttaaa gaccagttag ctgcacttcc acctgaaagc gtctcaatca ctttctttaa
    41641 atcaagtccg tttttttgtg catagacaag catttccgtc attcctgtca tcgtacctgc
    41701 aatcatgatc tgattagcca tttttgtatg ctgacctttc ccagcagaac catgcaatgt
    41761 aaatgtcgta ccaaattctt tgaataaagg cagtacttga tcataaacgg cttcttctcc
    41821 accgaccatg atcgtcagtg taccattctt tgctcctaag tcaccaccgg ataccggtgc
    41881 atctaacgca tctgcgcctt tttcttttgc tgtttttgca attttttctg ccaggcttgg
    41941 tgtacttgta gtcaaatcaa ctaaaatatg tcctgagata tctgcagaaa aaatccccga
    42001 ctgtccatag tagatttctt ctacatcttt ggggtaacct accattgtaa agagaatatt
    42061 actttgttct gctaccgctt ttggtgtatc tgcccagata gctccttctg ttactaaagg
    42121 atcagctttt gcttttgtcc gattatagac agctacttcg tgtcctgctt ctagtagatg
    42181 gcgtgcgaca gcacttccca tgacgcctgt tccgataaaa ccaagtttca ttttttcgac
    42241 ctcctaaaaa tcaaaaatcc ttgcttctat gctagtatac gctagaaaca aggatttttt
    42301 cataaaaaat gtttgaattt tatcttttaa atgaatttaa ttttattttg attcgttcaa
    42361 tcgagtcttc ttcttctttt cttcgcatct cttcttcatg ataaacaacc atgtcttgat
    42421 aaaattcgat catagcttcg ccgaaatgtg tagatgaaat atcataaagt ttagcttcta
    42481 aaacttttgg atctttagga acttcactgg aaatataatc aataagtgct ggtgcaaagt
    42541 cttcgtcggt ttcaaaagtt ttccctaatg aaggatgatc gaacaatcgg ttcaaataag
    42601 catttccttc cacgacacaa ggtgttccgg ctgccatcgc ttctgtataa gtaagccctt
    42661 gtgtttctga agtagaagca ctgacaaaat aatctgccgc tttataataa agtgctacat
    42721 cattgttgtc cacttctcct gtgaactgca caaattcttc taactgcagt tctgagatca
    42781 attcctctaa ctcttctaca taaggtcctt ttcctacgat aactaatctg gcgttaggat
    42841 aagcggagat gacctgagga aacccattaa tcaaggcttg gatatttttc tcataagaaa
    42901 tcctgcttaa agaaagaatc atcaaatggt tttcctgaag acctagtgac tcccttaatt
    42961 tgctgatatc ctgctgagtg atatcagaac gtttgaattt ttcaatgtcg ataccagtag
    43021 gaatcacgcg aagcggtgct attacaccat agctgcgtaa tgtatcaata acacgttcac
    43081 ttggacaaac tacacctgtc gtatgatttg caaataatct agacaagtat tttacatggg
    43141 attgcctgat cacttttcct ttaccgatat aatgaaggta gtcttcatac atcgtatggt
    43201 aagtatggat cagaggtatt ttcaacttct tagctaccat cttcccaagt atccctgctc
    43261 cgaattctgt atgggtatga ataagatcta gttctagttc tttggcaacc aaataagcat
    43321 accacatgcc tctaacaaca actcttcgat ccttgaaaga aataaatggt acacttggca
    43381 ttcgaatcac atctttttcc aacttatccg cattaggatc ggtcgttgta aaaatataga
    43441 cttcatgccc atgtctttct aattcttgtt ttaatgtttt gatcgatgta gcaactccgc
    43501 tgacttgcgg aaagtaggta tcggtaaaaa agccgatttt catgtttttc gcctccaaac
    43561 tagtccttga cctgatttac tttttttaat ttgctagaga ctttttcatt cagtacactt
    43621 tcgtatacat ttttaagttc ttcaccgatt ttattgatac ttcgctcttt tgctgtttga
    43681 taaccggctt gtgtcgtact cggtagttct tgattggtaa tctgttggat cagtcggata
    43741 aattcttcgt ttgtcttccc catatagcag ttcttgctat cttctaacca gccattatac
    43801 actggaatat ctcgaacaag tacgttttgt ttgcttgcta aagcttctaa aacaacgatc
    43861 ccttctgtct cttcataaga agggaaaaag aatagatctg cacctgaata cgcaccttct
    43921 atgatctctc cacgaatgta accaggaaac aggacatttt caggatgatc ttcttttaca
    43981 attttccgga tgttccgagg aatcgagtac atgggaacat gaccaaacca aataaatgtg
    44041 tattcgggca tcttcttagc aatttctacg aaatcaatga ttcctttacg ttcgaaaaac
    44101 aaaccgacac aaatgattac tttttgatcc ggagacagtt tgaaatattc tctgaacttt
    44161 tgttctttca ttggatcagg gtgatatttc tctaagtcga tcccattgga aatagcttga
    44221 atcggcacac ggataccata gctttccaac aactgttttg aataaggtgt tggcgtgatc
    44281 agatagtccg ctttttggta caatcctacc agatattttt ttacgatagg agaaagctgg
    44341 ttcgatccga taaaggaatt tcggaaatct tcctctgtag aatgcgcatg atagacaact
    44401 ttttttcctt ctcttctggc tttattgacc atattatgac tattgattcc gtatgtattg
    44461 atgtgcagga tgtcataatc ttctttttca tctagtgtat aagagatacc gacttccgtc
    44521 agagcacgtt tttgatgatc aagcgcacgc ccgattccag attttgcaag catcttttca
    44581 ctttcaaaat ataataatac cttcacctta cgtccccctt cacttatata gtataacata
    44641 gcctacaaac tgtcactcaa acttaagccc tatttttgtc tattcttact gacaaaaacg
    44701 ttttcttaaa aaagaacaaa aaaactggcg tagctctttt acaagccaca ccagcttttg
    44761 atacgttgtt tattttacat attcatgaac aagttcaacg acttcttcca tcgtatcgca
    44821 ttctttcaat gcacgatcag caagttcagc cattttcgct gtgtccaagc gtttcattaa
    44881 actacgcgtt ttaagaatag atgtcgcact cattgagaac tcatctagac ccatacctac
    44941 tagcaatgga acagctgttt gatctccagc catttctcca cacatacctg cccattttcc
    45001 ttcagcgtgt gctgcatcaa ttacattttt gatcaaacgt aaaattgatg ggttatatgg
    45061 ttggtacaag taagaaacgc gttcgttcat acggtctgct gccattgtgt attgaatcaa
    45121 atcgttcgta cctacagaga agaaatctac ttcttttgca aacttgtctg ctaagactgc
    45181 tgctgctgga atctcgatca tgatgccgac ttggatcgta tcagatactt ccttgccttc
    45241 acttatcaat ttttgttttt cttcttcaaa gatcgctttt gctgcgcgga attctttgag
    45301 tgtagctacc atagggaaca tgatacgtaa attaccatga acagatgcac gaagcaatgc
    45361 acgcatttgt gtacggaaca tttcgtcgcc ttgttcagat aaactgatac gcaatgcacg
    45421 atatcctaag aatggattca tttcatgagg taattgcaga tatggtagtt ctttatctcc
    45481 accgatgtcc attgtacgaa caactacagg ttttccttcc ataccttcta atacagcttt
    45541 gtaagcttca tattggtcat cttctgttgg gaagtctgga gaatccatat acaggaattc
    45601 agtacggtac agaccaactg cttctccacc attattatgg acaccaacta gatcttttgg
    45661 tgttccgatg tttgcagcta attcaaaatg cttgccgtca gctgtgacag tttctgcatt
    45721 ttttaatttt tcccattctg ctttttgtgc tgcgtaatct gcacctgctt tttcaaattc
    45781 agctttttgt tcatctgtag gatcgatgat tacatcgcct tcgatcccgt tgacagccaa
    45841 aatatcgcct tctttgactt tagcagtaat ttcttttgtc ccaacgattg ctggaatttc
    45901 taaagaacgt gccatgatag cagaatgtga agtacgtcca ccaatgtctg ttacaaacgc
    45961 ttttacaaaa ttgcgatcta attgtgctgt atcacttgga gtcaagtcat gtgcaacaac
    46021 gaccacttct tcgttgatca ttgatggatt tggtaaagta acgcctaata agtgcgctaa
    46081 aatacgttta gcaacgtcac gaatatctgc agcacgctct tgcatataag cattatcttc
    46141 cattgcttcg aacataccga tatacatatc cgttacttct tttagcgctg attcagcatt
    46201 tacgctgttg tctttaatat tttgcttgat ttgacctacc atttctggat ctgaaagaac
    46261 catcaaatgg gcatcaaata cttgcgcttc tgcttcacct aagctttgcg ctgctttttc
    46321 acgaatttgc tgcaattctt cagtagattt agctaatgca gcatccaaac gagcttcttc
    46381 agccgcagta tcttctactg ttgccttact gaatgttaaa tccggttgaa ctagcaggta
    46441 agcttttgca acggctacac cgtcactagc ggcaatccct tttagcattt caaccattat
    46501 tcagataagc cttctttctt cattgtttca acgattgctg ccattgcatc agcttcgtca
    46561 gcaccttctg cagtaatagt aacatcagaa ccttgaccta cacctaaaga cataacgccc
    46621 atgattgatt tcaagtttac tgatttacct ttatactcta agtttacatc agagttaaat
    46681 ttgcttgctg tttgtactaa tagtgtagct ggacgagcgt ggatcccagt ttctgctact
    46741 acgtgaaatt ctttcttttc catattaatc ggtctccttt aagtgagtgt tgtttttatg
    46801 tgagggtttt cttttttagt aattcagaga atcctaacaa atgccaccct ttcatctgta
    46861 aagattaaca ttttttttcg ttagatacaa cagttttcat tcaatttcag ataaaagtat
    46921 tcaaattatt ccggattctt tttcatcctt ttcttcacat tttataacaa acgtgtttat
    46981 ttcctttttc ttgtcgcttt ctcttctcct gacgtttatc attctttcct ttgaccctct
    47041 ttgttttcat atgaaacgaa ttacttgctt ccctttttat ttttagtata ataagagtca
    47101 aaggtcagga atggtcaata gagatttcac cttttctacc tcataaatct cttaaaaaac
    47161 taggggttat tcttttacct catgaaaaac gagatgtaaa atatggatgt acccattttt
    47221 gtgaaaggac gtgaatgatt catgctttgt caaaactgcg gcaagaatga ggcaacgatt
    47281 cacttgtatg ccactgtcaa tggtcagcgg acacaactcg attactgtca gagctgttat
    47341 caaaaaatca aaaatcaaca aaatggaggt ctgactaata tggcccaaaa tgatccattt
    47401 ggatttggca gtttggacga tcttttccgt tccatgtctc gccaaatgca acagcaagga
    47461 aattatgagc aaacaccacc aacacaattt ggcggaaaca acaacttcaa tggtggtcag
    47521 ccacctcaag gcaatacaga aggtttattg ggagaatacg gaatcaatat cacagaacaa
    47581 gcacgacaag gtgatatcga tcctgtgatc ggacgcgatg acgaaatcaa acgagtcatt
    47641 gaaattttaa atcgccgaac caagaacaat cctgtcttga ttggagaacc aggtgttggt
    47701 aaaacagcag ttgttgaagg tttagcacaa aaaatcgtag atggtgatgt accgcaaaaa
    47761 ttaatggaca aagaagtcat tcgtttagat gtcgtatctt tagtccaagg tactggtata
    47821 cgaggacaat ttgaagaacg tatgcaaaaa ttgattgaag agatccgtca agcagaaaat
    47881 gtgatcctat tcatagatga agttcacgaa atagtcggtg ctggttctgc tggtgatgga
    47941 aatatggatg ctggtaatat tttaaaacca gctttagctc gaggagaatt gcaaatggtt
    48001 ggtgctacta ccttaaatga gtaccgcatc atcgaaaaag acgctgcttt agaacgtcgt
    48061 atgcaacctg tacgggtaga tgaaccaact gtcgaagaaa cgatcagtat tttgaaaggt
    48121 ttgcaaaaac gttatgaaga ctatcatcat gtaaaatata ctgatgaggc catcgaagca
    48181 gccgcaactt tatccaatcg ttacgtccaa gatcgcttct tgccggataa agccatcgat
    48241 ttgctagatg aaacaggttc taagaaaaac ttgacgatcc aaatcgttga tcctaaaaca
    48301 atcgagaaaa aactgcaaga agcagaagaa caaaaagttt tagcttctcg agaagaagat
    48361 ttcgaaaaag cagcttatta tcgcgatcag atcaataaac ttcaaaaaat gaaagaacgt
    48421 cagctcactg aagaggaaac acctgtgatt accgaaaaag atatggaaaa aatcgttgaa
    48481 caacggacag gtattccagt gggtgaatta aaagaaaaag aacagacaca actgaaaaac
    48541 ttagcagatg acttgaaagc tcatgtcatc ggacaagata acgctgtaga tcgagtagcg
    48601 aaagcgattc gccgaaaccg tgttggatta aacaaacaga atcgtccaat cggctccttc
    48661 ttatttgttg gaccaactgg tgtaggtaaa acagagcttg cgaaacaact tgcctacgaa
    48721 ctattcggtt cacaagattc aatgattcgt ttcgatatgt ctgaatatat ggaaaaacat
    48781 agtgtctcta aattgattgg ttctcctcca ggttatgtcg gatacgaaga agctggtcaa
    48841 ttaacagaaa aagtacggag aaatccttac agtcttgtct tgttagatga agtagaaaaa
    48901 gctcatccag atgttttgca tatgttcttg caaatcttag atgatggtcg attgacagat
    48961 gcacaaggaa gaacggtcag ctttaaagat acgatcatca ttatgacaag taatgccgga
    49021 actggtaaag tagaagcaaa cgttggtttt ggtgcggcac gcgaaggtgt tactcgttct
    49081 gtattgaacc aattaaacaa ctactttaca ccagaatttc tgaaccgttt tgacgggatc
    49141 atcgaattca gtgcattatc aaaagaaaac ttgatgacaa tcgtcacact aatgctagac
    49201 gatgtcaacc aaatgctggc agcacagcaa cttcacatcg aagttcctac gaatgtcaaa
    49261 gaaaaattag ttgacttagg ctatgatcca tctatgggtg ctcgtcctct tcgacgcacg
    49321 atccaagaac aaatcgaaga tggtatcgct gaattttatc ttgatcaccc ttctatccat
    49381 gagttgaaag caaaactgga taaagatgga aaaatcatcg ttacttctaa accagaacgt
    49441 ttggctaaag aatcagccga agaaacggct gaataaatcc agttttatag cgtgagacgg
    49501 tatttctttg agaaatgccg tctcattctt ttttcagaaa agtcaaaata ctgttcattt
    49561 tataaaaaag aaattataat aagagaaaca agcaattaaa aatacataaa agaggtgagc
    49621 gccatgaaat tggtaaatgt aacaaacagc cattcccgtc ttgtattaaa ccagcttgaa
    49681 aacactgatg cccatctagt caaggtctac acagccggaa ataccactat tgtctacact
    49741 gaagcccctg aacataatga aattctgctg atcaatgaca aacgtaaaat ccagccgaaa
    49801 gaaatcgaag atgctaaaaa ttatttctta gataaaatca aagacgccgt ttaccacgag
    49861 gatgaaatca aagtaatcga attggcaggc cttgttgaaa tctcgattcc aaaacatgaa
    49921 ttaggcgcta cattagccgt gtaaacaaat tttgaacata ataattaaag agcgtgggac
    49981 aaaagtaaa
//
LOCUS       DAPBAF010000020        49305 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.020, whole genome shotgun sequence.
ACCESSION   DAPBAF010000020 DAPBAF010000000
VERSION     DAPBAF010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 49305)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49305)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49305
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.020"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            131..505
                     /locus_tag="RD451_001290"
     CDS             131..505
                     /locus_tag="RD451_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HDT7566561.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(619..1248)
                     /locus_tag="RD451_001291"
     CDS             complement(619..1248)
                     /locus_tag="RD451_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HDT7566562.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1382..1454)
                     /locus_tag="RD451_001292"
     tRNA            complement(1382..1454)
                     /locus_tag="RD451_001292"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1419..1421),aa:Thr,seq:ggt)
     gene            1668..1741
                     /locus_tag="RD451_001293"
     tRNA            1668..1741
                     /locus_tag="RD451_001293"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1702..1704,aa:Asn,seq:gtt)
     gene            complement(1879..2043)
                     /locus_tag="RD451_001294"
     CDS             complement(1879..2043)
                     /locus_tag="RD451_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566563.1"
                     /translation="MKNLIAGGFLFVGGGILMNTDNFGNVIPFLGAACALIGVGMLIY
                     FVFSDDGKYG"
     gene            2338..3666
                     /locus_tag="RD451_001295"
     CDS             2338..3666
                     /locus_tag="RD451_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HDT7566564.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            3868..4701
                     /locus_tag="RD451_001296"
     CDS             3868..4701
                     /locus_tag="RD451_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HDT7566565.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            4717..5454
                     /locus_tag="RD451_001297"
     CDS             4717..5454
                     /locus_tag="RD451_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HDT7566566.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(5609..6577)
                     /locus_tag="RD451_001298"
     CDS             complement(5609..6577)
                     /locus_tag="RD451_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HDT7566567.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            6809..7642
                     /locus_tag="RD451_001299"
     CDS             6809..7642
                     /locus_tag="RD451_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HDT7566568.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKVLNIKPDGLNPTQMDL
                     F"
     gene            7676..8515
                     /locus_tag="RD451_001300"
     CDS             7676..8515
                     /locus_tag="RD451_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDT7566569.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            8541..9101
                     /locus_tag="RD451_001301"
     CDS             8541..9101
                     /locus_tag="RD451_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HDT7566570.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            9300..11021
                     /locus_tag="RD451_001302"
     CDS             9300..11021
                     /locus_tag="RD451_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HDT7566571.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            11186..12328
                     /locus_tag="RD451_001303"
     CDS             11186..12328
                     /locus_tag="RD451_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HDT7566572.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            12344..13555
                     /gene="thiI"
                     /locus_tag="RD451_001304"
     CDS             12344..13555
                     /gene="thiI"
                     /locus_tag="RD451_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HDT7566573.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
     gene            14128..14775
                     /locus_tag="RD451_001305"
     CDS             14128..14775
                     /locus_tag="RD451_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HDT7566574.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     misc_binding    14904..15120
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            15168..17813
                     /locus_tag="RD451_001306"
     CDS             15168..17813
                     /locus_tag="RD451_001306"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HDT7566575.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            18123..19436
                     /locus_tag="RD451_001307"
     CDS             18123..19436
                     /locus_tag="RD451_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HDT7566576.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            19426..20079
                     /locus_tag="RD451_001308"
     CDS             19426..20079
                     /locus_tag="RD451_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HDT7566577.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            20134..20805
                     /gene="radC"
                     /locus_tag="RD451_001309"
     CDS             20134..20805
                     /gene="radC"
                     /locus_tag="RD451_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HDT7566578.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGIYKLVHINYIRKFTVILPSGNTIMLSIIERHNAFFSS
                     SEDSL"
     gene            complement(20700..22052)
                     /locus_tag="RD451_001310"
     CDS             complement(20700..22052)
                     /locus_tag="RD451_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDT7566579.1"
                     /translation="MKRVALYMRVSTEQQAKHGDSLREQKETLYEYIEQHKDLKVVNE
                     YVDGGISGQKINRDEFQKLLQDVKENKIDLILFTKLDRWFRNLRHYLNTQEILEKHNV
                     SWNAVSQQYYDTTTAYGRTFIAQVMSFAELEAQIDSERIKAVMANKIAQGEVVSGKTP
                     LGYSIENKKLVINDDAPIVIDIFNYFLSSGSLRKTVYYLGSQYGIVRDYQSVKNMLTN
                     KKYIGELRNNKNYCPPIIDKKLFYAVQKALPKNLKTNAKRDYIFKGLLKCSDCQGSVA
                     GQTIKARYKKKDGTESIYERTCYRCVKRRNNKLRCTNKRAFYEKNLERYIFEATKQKF
                     EQIQINYSKKQPKIIKKKNSKKNIENKLDRLKKAYLNEVIDLEEYKKDREALMKELNE
                     IEVEPAKIDIKNVEFILSKEFDEIYKESSEEEKNALWRSIIDNIIVFPDGNITVNFLI
                     "
     gene            complement(22118..23407)
                     /locus_tag="RD451_001311"
     CDS             complement(22118..23407)
                     /locus_tag="RD451_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HDT7566580.1"
                     /translation="MGVLLFLVGIVLIIMGSSKLSEAKKLKDKTSALESKVKEYSQEL
                     NARETFISEKEKNISKLNKNLSTLENKIDILNAESQRLDDEINQKYDTSLVTIYKSVI
                     IPNIDETSSSEIKNKLSLLKIKEKDFILDGAINIPSYLNNREANNIKKKMLIPLESEI
                     TGLLNKLTISNVDSTREKIIRTFDKINKLFKNDEAEFKKELLELKLQELELNYSYIVK
                     VNDEKEQQKAIKEQMIEEEKVRREIEREKKRIDKEERQFNSEITKLMAYMQKASADVE
                     KELYADKIKELEEKLRELETVKEDVLQRELNTRAGYVYVISNIGSFGEDVYKIGMTRR
                     LEPMDRIKELSSASVPFEFDVHAMIFSEDAPTLENQLHSHFRKNEVNKVNQRKEFFKV
                     SLDEIEKVVLENYNGTVSFTKLAQAEQYRRSLELTDV"
     gene            complement(23494..24198)
                     /locus_tag="RD451_001312"
     CDS             complement(23494..24198)
                     /locus_tag="RD451_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LexA family transcriptional regulator"
                     /protein_id="HDT7566581.1"
                     /translation="MFAENLKFLREKYNIDQQELAEKLGRKSSSSISEWEKGKYTPKL
                     KTLNEIAKIFNVDIDDLMNIDLSISNQIYNILPIYNQLNDENKVATYEFASNRLEEQK
                     QENVLDFPKKEKIPTVHNSASAANPTELTYGDTVVEEEEFERVPSAADFAVPIIGDSM
                     EPVIRNGQFVFVKEQPDVEDGEIAIVELGGDGVTCKEIYKDYENQTIILRSINDLYED
                     RIVSPEQIRIIGKVVF"
     gene            24398..24664
                     /locus_tag="RD451_001313"
     CDS             24398..24664
                     /locus_tag="RD451_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7566582.1"
                     /translation="MDTAKKEKYTLRQLRALKGYSKEELSRKSKVTSRTIFIYENDVD
                     KMRNGKYATLEKIAKALGVRVSDIFLDPDSEKPKSITGETKQVS"
     gene            24677..24835
                     /locus_tag="RD451_001314"
     CDS             24677..24835
                     /locus_tag="RD451_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566583.1"
                     /translation="MEEKNIKVPTLEEYTKIVVETDEQNPKTIAVITANDIESCEGFR
                     VRMTPRYD"
     gene            complement(24832..25062)
                     /locus_tag="RD451_001315"
     CDS             complement(24832..25062)
                     /locus_tag="RD451_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HDT7566584.1"
                     /translation="MGKNQWVSPRNGKWAVRGEGNSEDTKLFDNKSDAVEYGKKISKK
                     QQSEFIVQKKNGQIQSKDSFGNDPIPPRDKEH"
     gene            25134..25289
                     /locus_tag="RD451_001316"
     CDS             25134..25289
                     /locus_tag="RD451_001316"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566585.1"
                     /translation="MSNKPKITLNGTPNLQRLADEMARIRSRHWGVTVVATIIEQKEK
                     PTQPASK"
     gene            25446..25601
                     /locus_tag="RD451_001317"
     CDS             25446..25601
                     /locus_tag="RD451_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566586.1"
                     /translation="MKEESKIGILNENNYTRLIIETEEGEKVAEVTLTDATPADGYRI
                     RLTPKYD"
     gene            complement(25598..25822)
                     /locus_tag="RD451_001318"
     CDS             complement(25598..25822)
                     /locus_tag="RD451_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HDT7566587.1"
                     /translation="MGKNQHVVPNSNGGWNVKGAGNSKATAHTNTKSEAVKIAREISK
                     NQGSELFIHGRDGKIQSRDSHGNDPHPPKG"
     gene            26089..26424
                     /locus_tag="RD451_001319"
     CDS             26089..26424
                     /locus_tag="RD451_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566588.1"
                     /translation="MNKKIENLIEELKRECQKQGVSIICTAQKEGELKSLVYGETTEI
                     LLCLAMQEEHLDENLPLSAHIMRRIAVDAYEQAKNEEENQPSNHTFVINNKEDLADVM
                     TRILKGEFQ"
     gene            26657..27598
                     /locus_tag="RD451_001320"
     CDS             26657..27598
                     /locus_tag="RD451_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqaJ viral recombinase family protein"
                     /protein_id="HDT7566589.1"
                     /translation="MSKSTLEMSHQEWLEDRKRGIGGSDVATVLGLNKYKSPYQLWLE
                     KTGQIELKDLESEPAYWGNVLEEVVAKEFQERTGKKVRRRNQVFEHPLHPFLRANIDR
                     EVVGENAILECKTANQFLGKEWEGEEVPLSYLCQVQHYMNVLNKDYCYIAVLIGGQKF
                     IWKRIERDQELIDTITEQLVEFWETNVLGGIEPVIDGSGATADFLKEKYADVEENQTA
                     LPSRFDELIEQKRELKRTKKEIESSIRQVDNEIISELGKREASIGITQRNIISWKLVR
                     TRRMNTKKLAEKYPDVANDEEIYNVTESRRLTEKEIK"
     gene            27600..28490
                     /locus_tag="RD451_001321"
     CDS             27600..28490
                     /locus_tag="RD451_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HDT7566590.1"
                     /translation="MATNESLKNQLAEKPQKQVAPGQLGLKALMNTPTMRKKFEEVLH
                     DNANAFMSNVMTLVSNDSYLADSEPMSIMSGALTAATLNLGLDKNLGYAYLVPFNSKN
                     KQTGKWEKKAQFMLGYKGYIQLAQRSGKYKALNVIEVYEGELKSWNRLTEEFEFDPNG
                     RTSDEVIGYVGYFELLNGFKKTVYWTKQEIEAHRIANNKDRDKTKLSGVWASDYNAMA
                     RKTVLRNLLSKWGILSIEMQEATTSDERVQRVQEDGSIIAETEVEEDIPERKEAEVIS
                     EENEDVQTGLFDASNPPLNK"
     gene            28533..29333
                     /locus_tag="RD451_001322"
     CDS             28533..29333
                     /locus_tag="RD451_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HDT7566591.1"
                     /translation="MNTGYVKLHRKVMNSFVWTNPYMYKLWSLCLMKASHENRKILFN
                     GKEIQVNSGEFVTGRDAITSEMNEGVKREHQVNSGSVWRWLKQFEKNGMLNIKSTTKY
                     SVISIKNWSLYQSSEQQMNIKRTTSEQQVHTNKNEKNYKNEKNNKTSSSQPRKKRVYD
                     TDSVYYILAEELFKQICQNQEIKKPNLQSWADNIRKMIEIDKRTENQVRGMIEWSQHN
                     VFWASNILSAKKLREKYDTMAAQANRDYKTKQTKTLEYEKFSTDELPI"
     gene            29348..30199
                     /locus_tag="RD451_001323"
     CDS             29348..30199
                     /locus_tag="RD451_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDT7566592.1"
                     /translation="METVGEIMEKLIQKVLVQRGECPECGQPLYGWRTKNPDGSERCK
                     PTCMQCGYKALRVQEDLQTERIYNESLKARAINFFKGGSVVPNQALFDCTLQNYQIVD
                     QETRQAVEVTKRFVNSVLLGNPSHLVLTGKQGTGKSHLAMAAAWEVLKRSNYDKKILF
                     IGLQEMLDQIKFSYNNPELRKTIEGSLIADIKTADLVIIDDIGSELGKDASDSRAFGI
                     NTLNSFLDARQNLATIITTNLLGEELKKAYGTRTISRMFVNSDGFTMVFSQTADKRIK
                     PVKGSIA"
     gene            30196..30555
                     /locus_tag="RD451_001324"
     CDS             30196..30555
                     /locus_tag="RD451_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HDT7566593.1"
                     /translation="MNKYRNKKTVHRGIKFDSIAEAEYYDLALWQAEANGWKVKLQER
                     FELMPKFELEGKKYRKIEYIPDFTFYKSGKLVKVVDVKGMQTKDFKIKAKLFCHQYQV
                     PLILAKKYRNTFKEERF"
     gene            30570..30731
                     /locus_tag="RD451_001325"
     CDS             30570..30731
                     /locus_tag="RD451_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HDT7566594.1"
                     /translation="MTTEEVIQMRIRSLRREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIRRLEE"
     gene            30728..31054
                     /locus_tag="RD451_001326"
     CDS             30728..31054
                     /locus_tag="RD451_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566595.1"
                     /translation="MSVDKEAAWRKLMLLIQDENWQEDEAVVAEVQRLGKIANGRIRK
                     KPDKRKQRKGKIVVVLHEGKILMQGTASELSAETGYTRGTIRTYAWRNHTDRKGHEYK
                     YLEEEK"
     gene            31051..31866
                     /locus_tag="RD451_001327"
     CDS             31051..31866
                     /locus_tag="RD451_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prohibitin family protein"
                     /protein_id="HDT7566596.1"
                     /translation="MNENKLIKLGVAGAVIVGIGVIGGFKFFEKIDNGYVGVRYSMNG
                     GIKDEALTQGVKFVGIDKVIQYPIRLQTIQSKNISVSTSDGKKTTIDIKYDYKVDSTK
                     AAKMYKEFGNITSEDIESGWLKSKLQKVAREVYAKYSLLDVLSGDSSKVEAEVLTNFA
                     KSVESKGFEVEDVTLGVPDVDKETQKSIDAIIRAGQENEKAKLDAETAKTQADSEAYK
                     KTKAAEAEAESNRKVAESVTDNLIRYEEAQARKKHGWVTVNGADTVVTDEAGK"
     gene            32005..32316
                     /locus_tag="RD451_001328"
     CDS             32005..32316
                     /locus_tag="RD451_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HDT7566597.1"
                     /translation="MDELITKVEQWAKDKGLDQADPKAQFLKVAEEFGEIASAMARSN
                     DELFKDSVGDVIVTLIILSMQKGTNVQECLEMAYNEIKGRTGKMVDGVFVKSSDLEDV
                     K"
     gene            32313..32543
                     /locus_tag="RD451_001329"
     CDS             32313..32543
                     /locus_tag="RD451_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566598.1"
                     /translation="MKYEIPLSEAGIQAIINGREVNIELPDGTELVIRQSYLKDMAAP
                     VLIDRFNVTDSVVENHLKEFRSSIDNTFRLGS"
     gene            32550..32753
                     /locus_tag="RD451_001330"
     CDS             32550..32753
                     /locus_tag="RD451_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PIN"
                     /protein_id="HDT7566599.1"
                     /translation="MNTRHRRVAKLRKQELNVLKTKFEKEYGISAEETYKVASQFVAD
                     ASDAIRKFGISILNDDRKWEEMR"
     gene            32750..33046
                     /locus_tag="RD451_001331"
     CDS             32750..33046
                     /locus_tag="RD451_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566600.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKTRKKSKFKVGDMVRCEA
                     EEFVYPFRGYVKKILSNSAIIRIENTMKCDRSTAKHKHYLAVARLVDMEVIKSK"
     gene            33123..33536
                     /locus_tag="RD451_001332"
     CDS             33123..33536
                     /locus_tag="RD451_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HDT7566601.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIETERDAILAALMALSLISRQILYYSFCVPDSFSNYRI
                     SREVGYSERSIQRMKSEALIEFAEAYKHGRIIAYK"
     gene            33549..33935
                     /locus_tag="RD451_001333"
     CDS             33549..33935
                     /locus_tag="RD451_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566602.1"
                     /translation="MWKDYVSLKELKKDLVFKRIVEWSESELILEDGTKMEVVCSESD
                     CCAWAEGEFKNVKLDAVITDIKIFDKGNRLYNGDGHTSYAEVVVYHNRNEIAKAECTA
                     NDGNGGYYYSVCALKVKDKLCIVTDA"
     gene            34486..34710
                     /locus_tag="RD451_001334"
     CDS             34486..34710
                     /locus_tag="RD451_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566603.1"
                     /translation="MRTYWYVSLNNKYPKPMKGQHRRVVMSVQMKAKYSIVEMIREAT
                     PVEIDYCKLVYCGCGRWKEDHVQKNISKYI"
     gene            34728..35156
                     /locus_tag="RD451_001335"
     CDS             34728..35156
                     /locus_tag="RD451_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566604.1"
                     /translation="MEKSDTKANRYKPTAAEKKLLEVLINPDNLGKPVQELCSLAKIG
                     RTKYYDAMSKDGFVDLVNETTMDLIKGKASDVLNATYKYALTEKGHQDRKMILTIAGI
                     YADKQELKHSGGVDIRKQYEKMSDEELEELVKRYEKINDS"
     gene            35134..36552
                     /gene="terL"
                     /locus_tag="RD451_001336"
     CDS             35134..36552
                     /gene="terL"
                     /locus_tag="RD451_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase large subunit"
                     /protein_id="HDT7566605.1"
                     /translation="MKKSTTLNRVEYAVVQRELAIRKARKSFWLFCQLLYPEFYKDDR
                     LYLKDLCHTLQDFYEDKIDKKILVINMPPRHGKTFTARLFVLWMFGQNPKTKIITGSY
                     NQILSSLFAQQTRDGIMVENENVKAEYFKDIFPEVQIKYGDAAKGFWSLDGSEEKNYL
                     ATSPGGTSTGIGANYVIVDDIIKTAEEAYNERVLDSHWEWYNNTLAQRMERPRKQILI
                     MTRWSSNDLAGKMLTRRKNNVHQICYKAVQEDGSMLCNEIMTHDEYLDVVQEMNVDIA
                     EANYQQEPIDQKGRLYQKFLTYDTLPDNIIKIWNYTDTADKGADYFASPVFAETSDHD
                     AYIIDVMYTKEPMETTEIAHANMIIRNRVNKVRIEGNNGGRGFRRNSERITKERGYRG
                     AVFEDFHQSDNKLSRILANSAWVENHVYYPDDWATRWPDFYEAMVSYQREGKNAHDDA
                     PDAVTGIAETIIEADDFEFIAY"
     gene            36564..38099
                     /locus_tag="RD451_001337"
     CDS             36564..38099
                     /locus_tag="RD451_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010779952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDT7566606.1"
                     /translation="MFYSGITLKKYKRLRTKYSTQIEEGLFDPNAFMEDMKPFFDDRE
                     RKYLAYTSEKNEIDSREKPKTKIIKVNNKIHAGMYSVVVDQAVNHFTGIPIKWDYDVS
                     EQKRTFIQRMRDKLLGNDISAPSTPEEFETLTRQLSTMRFGMLDPDTATFQGATGLAF
                     RLLEPVETNDGWELRASNIEPWKAEKYENGAVYIKEKYDPYQKKFYEEMKVVTPKSIF
                     TYARYTDYPGTVQGAFKTLGNVPNPLGVINLTEFKNNTNRYCDFEVAEEISDAIDRVL
                     SDQQNEIEQFKLAYMLITGADLSEDKAKKMMEQLGIINLKDPNAKAGYVTKDLQKDFN
                     EYHFDLLKKQFYTVCKAIDFNDEVFKSNSSGEARKWQIISLEAKTNTKEQYFREGLKE
                     CAEVMAAYLDFAEKVTIDPEKIIFTFSRSLPTDLSYLAEALPKLAPYVSKRTIQSQIP
                     FVTDVDYENEMIDVESRQSYPDGEYGGGIVESNRNEVLDQTSRTGRFSKTQNGKSNAK
                     ETK"
     gene            38179..39057
                     /locus_tag="RD451_001338"
     CDS             38179..39057
                     /locus_tag="RD451_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HDT7566607.1"
                     /translation="MMEFYSTSDQKKYREYVEKNYKSLKMYDAKYKEFIEEYFPSFDY
                     AKVNRLLQMRSDIFRILAESAIDADVNKYFSDRLEDILQRSYVSNANVFAQILNVDLP
                     NYLSKEELERYLNYPWSGKTFSRRLWGNISSLEQKLSNAITTSVASGEGVLVALRTMR
                     EDPEICDMFKREESKYNKAIENLVRTEYAKFAQDGIEKSYIETGVDEYNVLTAKDEKV
                     CSICGGKAKNNPYKLSEAIIGENRAPFHGRCRCTDVPNMPKLGKDIDEEYERLFGDLL
                     DEFAHDSFGINLKRRK"
     gene            39059..39376
                     /locus_tag="RD451_001339"
     CDS             39059..39376
                     /locus_tag="RD451_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566608.1"
                     /translation="MKDFFEAVLTINVNADIAEAYKTAIESENHPNGLRDHWNGNYAY
                     VVIGDQTVNYQDNTPVDKNTVNLTIQLLSHSLPNLKETVDWYENMGCIVVRTDYKEGK
                     SSN"
     gene            39503..40126
                     /locus_tag="RD451_001340"
     CDS             39503..40126
                     /locus_tag="RD451_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HDT7566609.1"
                     /translation="MIMKHKSLMPMNLQYFAEGDDQKFSFDDFKSFVESNEEAQKFIQ
                     SQSQSVADKQLEAWKQNNLDKIKQDTIKEYEESKKNKSPEQIQLEKLQAEFEAEKALR
                     VTSDNKAFVAEQIAGLELDGELKESISQFMLNNLVSSDTDFTKNAVEGFTSVLNAINE
                     KHADALKELQMKSAFGGTQQSNNQVQQNNETLTNPEEQLGQILQQFN"
     gene            40141..41031
                     /locus_tag="RD451_001341"
     CDS             40141..41031
                     /locus_tag="RD451_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5309 domain-containing protein"
                     /protein_id="HDT7566610.1"
                     /translation="MKKTSLNNLEYLDISPAINAMQVPNTPFLSYLLGAGKTEPANST
                     EIKWREYDINNDDSSEKLEGGEYPDAESGRTWFNNYTEIFRKSTSVSGTLDAINVNGV
                     GNELTNQVALRGMEMKIDLNRKLITGVKADENGSKGRRMNGILNLINSANKAETATAG
                     AVTRKDIDTLFKLMYEKGYMGEKLCLISPDMQELMTDELDGKSTKIVQFGERVTFGLQ
                     IGNIVSNYGTGIALLEPSLPKGTIAAIDTNYVKLRPLREWRAEELAKTTDSRRIGLVG
                     EYSLEYNASNSGAILNLKSE"
     gene            41054..41269
                     /locus_tag="RD451_001342"
     CDS             41054..41269
                     /locus_tag="RD451_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566611.1"
                     /translation="MIGGITVVKKDETKKDEVVKYRVGKTKNFVGFVHPKTRRFITAD
                     SNNEFIISIDDKEAIAILEDAIDVNEI"
     gene            41281..41622
                     /locus_tag="RD451_001343"
     CDS             41281..41622
                     /locus_tag="RD451_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566612.1"
                     /translation="MDESLKTEIIESTKEDFPDLSEERITNLLEIILLEIESYNTCKN
                     DISWEKLKSVISEVLYKIIKNESEKTVSSVRRGDTTISYASTTNDVSELLLGYGDLIR
                     RVIGCGGLEFF"
     gene            41622..41993
                     /locus_tag="RD451_001344"
     CDS             41622..41993
                     /locus_tag="RD451_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566613.1"
                     /translation="MNEADILETTYEDSCIIERLTDIEDSNTNITIQDYKKVYDNPIS
                     CALSQGQIDGLAVIEDGEMVNVSTDTYKLFVHPKIKLKKGDRITITQKASGLIFSLFA
                     TKPFYYPSHCEVNLIGSEKNG"
     gene            41986..42381
                     /locus_tag="RD451_001345"
     CDS             41986..42381
                     /locus_tag="RD451_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HDT7566614.1"
                     /translation="MGNLKYESNAEKIIENFKNMTVIAQKEGISFVNDSMNKVVSLAK
                     PLTPVKSGNLRRGYRVVKARKLSSGRIVGAVINNEHYFKYVEEGHRTKNGGFVKGKFM
                     LTRATNLANMSYIPRRFKQMAIKIVKKGK"
     gene            42383..42760
                     /locus_tag="RD451_001346"
     CDS             42383..42760
                     /locus_tag="RD451_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566615.1"
                     /translation="MKDEIIAAISSKLKEIYPDGTIYLDSVMQSTKDFYFVLSVMESG
                     TENVGIDIQNVSFLIDIALIDNKPNRNLINELVSRCGTFFNTITIDEQILFPKAYLPD
                     EADGVQHIRFTLEFPQYIEWSER"
     gene            42761..43369
                     /locus_tag="RD451_001347"
     CDS             42761..43369
                     /locus_tag="RD451_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDT7566616.1"
                     /translation="MGEKRSKTGIISVEKPTWFPLEDETGNFPVYGTALPMGTAVSIK
                     PTANYETTQDYGDSVVQDQFTAFGGAEVELEANGYTHKVLSTITGGKIVKGGALRSGE
                     DIAQDGAFAYRRKKSNGKYRYTVFYKGQFALDSDETSTIEGSKVSFTHPTWKGSFVDV
                     PGLGYMYSVDEDDEGVDKAMIGNWFTKVAIPIEEAELSGGTE"
     gene            43369..43710
                     /locus_tag="RD451_001348"
     CDS             43369..43710
                     /locus_tag="RD451_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566617.1"
                     /translation="MSKYQTTIKLTKKDEEGKYEQVQFKSAEFLPGTVVEDAAGVMEE
                     MQTATDKQSVKKALSRAYSFIADTLFEGQFTGEDYCKGIDAREIASLTGKLLKSVTAG
                     FDETYTETKKK"
     gene            43952..46741
                     /locus_tag="RD451_001349"
     CDS             43952..46741
                     /locus_tag="RD451_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HDT7566618.1"
                     /translation="MILDESGFTAGMNNAVKKLNSFDETIERKSRNSGSSLGSIWKIF
                     AGSFLASGVTRIVGAGFDLIKGSISGAVDRVDTMNNALRNFQNMGFSNSEIMKNIGKN
                     GLLSQGIQGLPTALNDAISHVQLLASSTGDLTRSTQIFKALNDGILGFGGSTDQVNEA
                     VIQLSQSFSNGKVDAQTWNSMINAQLGPTLSAIAKKMGITMGDLKEGLSQGKISVEEF
                     QNQLIEMDTKGGGGLKSLSQIAKDSTKGIKTSIQNAKTAVTRGVGEVIEGLNKALVDS
                     DLGGFKGIIDKVGSSMESFLKVIAANIPTAVSFLSNLFNEIQKFGSALKFMMPFLVPA
                     ATAFGAFMFQLKGIPAIIKSFNNFKNAIIGVGNSLKIMGAIAAANSFVLIIGAVVGAI
                     AVFGYFMATNEEFRNKVISIWNDVKDSVIGVLKNIKDWGIDTWNSAKEMASNAVEGVK
                     DAWSGTKEWFSNTWKGIKDGATGLFDKTVETSRNAVDSVKNAWSNMKKWFSDTWQSIK
                     DSAREKWNEIKGSIMSVAGPLITGIKNAFLHVTFYLETLWNNLVEIGKNVFEILKNVI
                     LAPVLFITSMISGGWEETKNNMIAVWNNIKESAINIWESIKNIFVSYFTNIYFAALNI
                     WTGFKLTLINIWNEVVNQAKSIWLNIKYFFINLWIDIKYFAIQKWIELKFSIIQTWID
                     LKYNAITTWNNIKQFFKDTWKNIKDTAYNTWISIKNTMINTWNNIKDSFWNIVTGIVN
                     SAENAWTNLKNGVSNAINRVKEIFNSLREVNLFEIGKNIIDGLINGVKEKWNALKDTI
                     KGIAGNIKNWIKGALDIHSPSRWMRDMVGKNIVQGIIVGIDKEQSKLDQTMTNLVKTP
                     SVQPVVNGISHLPITQTKQNISASETKEIHLHLNVYGDLPDSMVRKITTKIKTELTRQ
                     MKRDAGAVGGTLYAT"
     gene            46731..47471
                     /locus_tag="RD451_001350"
     CDS             46731..47471
                     /locus_tag="RD451_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDT7566619.1"
                     /translation="MQLKRGQFFINQHYSSEFNVYIQNRPASVSASRVIELREREGND
                     SIIIDKGYYRNVTRKIECYYKAPSIDVVQEWEDRITEWLDMSSYSDFILYYDEQYIYQ
                     AVVIEGPEFKGTRKTGNIVPFEFTVSIRPFKENYNGRFTIRQTETFEIYNPEKYSSKP
                     LIKLSGSGDASFYINKDKYDLKSLDRELFIDSKLEEAYRKLDGNLEHQDQVTLFLDFP
                     FLYPGKNEIKWTKNIHSFEIMPRWWRKV"
     gene            47468..>49305
                     /locus_tag="RD451_001351"
     CDS             47468..>49305
                     /locus_tag="RD451_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDT7566620.1"
                     /translation="MKPRIYSPTETDFSTNGLGILKDCTRCEIYEVANGKYELELDYP
                     LGTRFDEYFENDYQIKAKPNDQEEYHIFFIDDKDIDTFLNTVTIYAQSRTNRLGRRVV
                     TLAEVDSKTGQEAISIIETKMDKKSDIRLYSDITAVSSTIFEARNVLNCIAGEQGSLL
                     QYWGGEIKREPFKLSLLKRRGRNNVGTIRYGKDMSGLKVKLDWTGIKTRLIPYADPQS
                     EVGTTNRIYGSPVDSAYINNYPDVYTEHVQFTEEQGVKDIKSLNKIAKNYFKTINPGC
                     DKPKVSITVEFDKLTDSEEAKEFAKIRNYGLFDTFKIYHKKYNIYLESKVSGLQYDSL
                     SEKTLKLEAGDIQVAFYQQQAVTIQDKLKDYATNNYMSDFNDYVSSMITGQGSAGGYV
                     SLWPKEKPSNIFIMDNPDLEKAREVLRMNKNGIAFSKKGWRGPFTSAWTLDSIFNANF
                     IQTGLIKADIFQNSFNKTGDVLKLVNGLLQIWNNKKKIMELTKKGMEFWNSKGSIGTI
                     GTTDSAGNPFPGASTPTPIEDNSLVIRTNGDGKYILISPKVGKGLVLLGNGKAIYFGD
                     LDVQGKLTVKGKEIIPGQGGGPSGGGESTGGYPSELKTDAEKRAWR"
BASE COUNT        17030 a         7743 c        10138 g        14394 t
ORIGIN      
        1 ctacactctg agatgtaaga aatatcataa gatatttctt acatcttttt gttttgagca
       61 ggactttaga taattttatt aatatatgct agcatgcttt tgtaagaaaa agaaagaggg
      121 cgtattagtt atgtatctta aaattacgga acaagcacaa gaaagattac aaaaatatat
      181 tgatgaaggc gcaacagtta tattggattt agatgatggc gttggggaat attctaaaat
      241 gggtgtttgc tctttagata ctagttttcg tttacttctt cttgataaag aacagagaaa
      301 aaatgattat aaactccaat tagatagtga tattggggat gtttatataa aagattattc
      361 aaaaatgtac atggatgaac atatgaccct ttctttagat ccacgtctag gtgtatttac
      421 tcttgaaagc ccaagtggtt ctttagacag tcatgttcaa ttagtagatc tacgaccaga
      481 aaaattctct ggaataaaac aataactttc tctctattgt ccataaaact agtctcaatc
      541 aagctgtatt gaaaaaacaa gacaacattc ttaccatggt aaataaaaag acgacacatt
      601 ttgtcgtctt tttttaaatt aactattttc gataaaagat cgcatagctt gtgccattat
      661 ttctggcttt tctctattca attcatgttt tccgttttta ataaagagta gccggccatt
      721 cgttgaaagt ttatataaac gttttgctgc tggtttattc gcatgatctt tggtaccgca
      781 taaaatcaat ttaggaagtc gtgatgtacg aagctgtttt ttgcagtcta atgtttcaag
      841 tgaacgaagt agggtaaggg tttgtttttt agatagacct aatttttcaa atatcttaga
      901 aggtacgcag taaaaataaa tattctggaa agtaagcaat aagcgattag gagactcaaa
      961 ttgtggagcg actaaaacaa ccttttttaa atatggagaa ggagttgcaa gatagtttaa
     1021 agcaataaca gcgcctaaag ataatccaca taaaataaaa ggttccttta tctgattcaa
     1081 ttgtacttcg atgtatttgg ttaagtcgtc taaagtagca gtgtctgtgc tgtttaaatg
     1141 attgaacaat gaaagacttt tgcaagaata actattgggt agataagaga ttacatcttt
     1201 ccatgattgt tcgtcttggc ctagaccatg caaaaaaaca attttcatat tgctctcctt
     1261 tttatagtta tcatatagac tttctttgta ctattaaaat ataaacattc atttcttacg
     1321 tcataaaata aaaaaacagc gcagacacat tgttaaacca acatgttgca ctgtttaagg
     1381 aagccacttg ccgggcttga accggcgacc tcttccttac catggaagcg ctctaccagc
     1441 tgagctaaag cggcattatc attaatacaa ataataggat aacgaatatt aatgtatttg
     1501 tcaacagaat tttttcgaaa aaatgtgttt ctctaatagg aaaacagatt ttagaaaaaa
     1561 taaaaataac aaaaaatgcg aacggtttct ttgataatat aataaaaaaa ttcaaaaaaa
     1621 gtattgcgtt atttagaaga aattgatatt atattcatgt acttgattcc ggcatagctc
     1681 agttggtagt agcgcatgac tgttaatcat gatgtcgtag gttcgagtcc tactgccgga
     1741 gtaaataaag cttatgcaaa gaaaaagaaa tccaatcact tgggtttctt tttcttttat
     1801 tattatgatg aatcaagctt tctgtttttg tcacgtatgt tgtaatcttt acgaaagagt
     1861 agagttggct actcataatc aaccatactt cccatcatcg ctaaatacga aataaatcag
     1921 cattcctaca ccaatcaaag cacaagctgc accaagaaaa gggatgacat tcccaaagtt
     1981 atctgtattc ataagtatgc caccacccac aaacaaaaag ccgccagcaa tcaggttttt
     2041 cattttattc atctcctttc ttacgttata gtatttcctt ctttcaatga gtattttgaa
     2101 agctatctta ttgtatgatg ttcttctagg cctcttcttt attatacagg ccattttcgt
     2161 tatctcatag aaatattcct ttttatctga aaactattgt ataccgtatg acatttttct
     2221 tcatgaagtt gtaagtatat tctcattcaa atgaaaattt catcatagaa gagattgtat
     2281 ttctaaattc ttaagagtaa aatacgaagt ataacttgga tttggaagga tgattggatg
     2341 aaagctatta cgcctgatat gacaacaaaa tttaacaaac agtttcaagc aaatatcaaa
     2401 cagcaggcat tgcagcgggc agttgtgaag aacggaatta ctgcttctgc tgaaaatgtt
     2461 tcagcacatg tggagaatac accggtattt tctatagatt tggctacggg gaaagtggct
     2521 aatcaaatgc aatcggggcg ttgctggatg tttgctgcac tgaacacatt ccgtcataag
     2581 atgctgaatc aattccattt aaaagagttt gaattatcac aaaattacac ttttttctgg
     2641 gataaatatg aaaaggcaaa ttatttctat gaaaacatca ttgcaacagg aaaagaggca
     2701 atcgatagcc ggaaagtagc tttcttactc gctactcctc aacaagatgg cggccaatgg
     2761 gatatgatcg tttcattatt ccaaaaatat ggcgttgtgc ctaaatcggt gatgccggaa
     2821 agtgcgaata gttcaaattc tcgagatttg aataactact tgaacaaatt actgcgtaaa
     2881 gatgcagtag tgttacggaa aatggttgct caaggagaaa cattagacgc tattgaagaa
     2941 aagaaagaag aaatgctaga aagcatttat aacttcttag ctatctcatt aggaacacct
     3001 ccaaaagaat tcgattttga gtaccgcgat gaagaaaaga actatcatct tgaccgagga
     3061 ctgacaccac aaatttttta tgataaatac atcggtgtaa aattagatga ttatgttagc
     3121 gtgatcaatg caccaacaaa agacaaacca ttcaatcgtt cttatacagt agagatgcta
     3181 ggaaatgtcg ttggcgggaa agaagtcaaa tatctgaatg ttgatatgga aactttcaaa
     3241 aaattagcga ttgctcagct tgaagaagga gaatctgttt ggtttggttg tgatgtaggt
     3301 caatcttcta ctagaactag tggcatcatg gccttagatg cttattcaat ggatgatcta
     3361 tttgatacgg attttacaat gactaaagct gaacgtttag attttggaga aagtctgatg
     3421 acccatgcga tggtattgac cggtgttgac ttagtagacg ggcaatcaac aaaatggaaa
     3481 gtcgaaaata gctggggcga aaaagttgga aagaatggct tctttgttat gagtgatgcc
     3541 tggatggacg aatatacgta ccaaatcgtt gtaagaaaag atttattgac gaaagagcaa
     3601 ttaaatgcgt tcaatgaaga accaattgtt ctatctccgt gggatccaat gggtgcttta
     3661 gcatagacga gtatttcaat gaagagtatg tagtaaagat aaaaagagct ggcttaagcc
     3721 agctcttttt atctttaaag tccattccct gttttttatg gtccctgtgc tataattcta
     3781 aataaaggat aaggattgga aataatcctt ttatcattaa aaatatgatg acgaagtaga
     3841 ataaaattgg gagtaggggg gaaagtcatg gatatccaaa ctgttttatc tgatctgaaa
     3901 ttaaatggta aagtgattcc agttgttggt ggcgatgtta atcagaccta tcgtataaaa
     3961 accgaacatc gtgcttattt tttaaaaatc catccgaatg taaaaaaagg attttttgaa
     4021 gcagaagtag acggattaaa agaactgtca gcattcgtac gtgtaccgga tacgtatatg
     4081 ctaggtgaaa caagtgaagg cgcttatttg ttaatggaat ggatcgagcc gggaaaaggg
     4141 gatcaacgag atcttgctgc agctttagct aatctccatc agcaaacagc gccacaattt
     4201 ggttttcgta aagataacta tttgggtaca cttgttcaga aaaattcttt tgaagaagat
     4261 tggtggactt ttttctttaa agatcggctt gaatcccaga tttctttggc agaagaaacg
     4321 aatcgatgga atgtacagcg tcaagaaaag tatctgcgat ttaaagaacg tgtattgaaa
     4381 tcggttgaac caaaaaagat cactccacgc ctcttgcacg gagacctgtg gagtggtaat
     4441 gtgttctttg accagcaagg gcatccagtt tttgtcgacc cagctgtttc ttatgggaat
     4501 cgggaacaag atattgcaat gagccagtta ttcggtggtt tccgaccgga atttttagat
     4561 gcttatcaaa ctatatttcc attagaaaag ggatggaaag accgactgcc gatttaccag
     4621 ttatattatc ttttggcaca tttgaatatg tttggagaaa gttacggttc ccaagtagat
     4681 caattactag aaaattttta agaggagggc gtgtttttgg caaaaaaata taccaaaaag
     4741 catgaagttt catattatga gtgtgacatc aaccaaacga tgacatttcc ttcgatgtta
     4801 ggagtagtta tcaaaacgtc tgaagatcaa agcgaccagt tgggaagagg cagtgaattc
     4861 gtcaatagct ttggacttac ttgggtcatc acgaattatt ccatggagat taatcgtctc
     4921 cctagagtcg gtgaagtaat ctcagtaacg actcaagcca tggagtacaa taagtttttc
     4981 tgttatcgga acttctggat ccatgatgaa gatgggaaag aattagtcaa aatagaatct
     5041 gttttcgtat tgatggattt tgtgaatcga aaaatgagca gtgttaatga agagatcatt
     5101 gctccttttg agagtgagaa gatcaagaaa atcaagcgtc aggaaaaaat tgaaaagatt
     5161 gattcgggct tcatgttgcc atatcgtgtt cgtttttatg atatcgatag taatcagcat
     5221 gttaataatg cgatgtattt taattggatc attgacgtat taggatatga ctttttgact
     5281 acgcatgttc cagaaaaagt aattattcga tttgataaag aagtagagta cgggaatgag
     5341 atcgaaagcc attttgaaca aatccctatc gaaaatggtg tcaaaacaaa acatgaaatc
     5401 cgaatgcaag aacagctgta ttgtgaagca aatattatat ggaaaaataa ataaaaaaga
     5461 ggttgtgaca gaagggggca acttcaagaa ataagaagaa atttacgaaa attgtttctc
     5521 aaatttttgt aaattttcga cttagttttc gaagaagcta tttttgtcac agcctctctt
     5581 tttaagttta gctattagat aatgatgttt agttttggat aaacgaaatc aattcttcac
     5641 ccgacaaacc atagtttaca gcaatcaata gttttaaacg tgctttttga ctattaatac
     5701 tgttacagaa aataatcccc attttttcta gttcttttcc cccgccttca taatcataaa
     5761 caggctctgc gattccattg aaacaacgag aaacaagtac tacagggatt ttttggacaa
     5821 gaagcttttc caaagcagct aaggcttgtg gagggagatt ccccgcacct aaagcttcga
     5881 ttaccaaacc gtctactttc gtatgggcga tggcttccaa taagtcccct tgcatcccag
     5941 catatgcttt aacgatcggg atagtcccat ctacagcgga aatgtccagt cgctttgttt
     6001 ctaaaagttc ctgcaagaat aaaattcgat tcttagttac taagccgatg ggacccaatg
     6061 taggtgttcg gaaagtagca acatttgtgg tatgggtctt tgtcacgtag cgtgcagaat
     6121 ggatctcatc gttcatgacc accaaaaccc ccttatctag cgcttcttca caacttgcga
     6181 cacgaatcgc actttcaaaa ttataaaggc cgtcacttcc aagttcatta cttgaacgca
     6241 ttgccccagt caaaacaatt ggtaatttgt tgccaatcgt tgtatcaaga aaaaaagcag
     6301 tttcttctaa tgtatctgta ccgtgtgtga tcaccactcc ggatatacct gatgcataag
     6361 cggacaagat acgttctttt aataccaaca tgtgagaagg catgatgtgt ggtgagggaa
     6421 gattgaagat atcttcaact aataattcta catgcttggg gattgtgatt tctgcatcta
     6481 ataatgggtt tgccacatca ggactaacac cgcccgtgag catgttttct ttcatggcga
     6541 tcgttccgcc ggtgtgtagt acaagtattt ttttcatttt acagacttcc ttacgaataa
     6601 ttttgcatag ccgttaaatc ttattgtata ctatataaaa gagttttgct atcagtgaag
     6661 aataacgaat agcctaactt atcataaaaa agctgacctt attaaaatgg aaaagactca
     6721 accttgacct cctaatacaa tggagtatct ggttgagttt cttttacaag aaagcagcca
     6781 aggaaatcaa tcacgaaggt ggccggaaat gatcagaatc ggattaacat cgtttaaaga
     6841 acatgacaaa ttaactggta aaaagaataa cactctttat gaatatgcag ggtttctacc
     6901 cttagtggaa ttagatactg cctattatgg aattccccga aagtcctcag ttgagaattg
     6961 gataagtgaa gtacctgaat catttcgctt tgtagtcaaa gtctatcaag gaatcagcgg
     7021 tcaaggagac tggaagcctt attatcagac cgaagaagag atgattgcgc attttttaga
     7081 tgttatgtcg ccaatggtag atgctggaaa gatgttttgc tttttagtcc aattcccctc
     7141 atcattcaaa tgtacgaaag aaaatgtcca gtacttgcgc aaacttagaa agtggtttga
     7201 gggttatcct gtttctatag aattgcggga ttattcttgg tacagcgatg aatttcttga
     7261 acgtacaaga aactttatgt ctagagccgc tttttcttta gccatcatcg atgagccaca
     7321 gttgctgaat acaacgattc cttttgatcc atttgtcacc aatccgaact ttgctctttt
     7381 tcgattccat ggtaggaatg cgcaaggatg gcaagcaaat gataaagagt ggcgtaaaaa
     7441 aagaacgtta tatcgttatt cagaaaaaga actgcaagaa ctagcacatg aagtcaaagt
     7501 agttgattct aagacaaaag aggtaggtgt gatttttaat aataattctg gtggtgatgc
     7561 ggctgaaaat gcattagcac tgcaaaaagt attaaatatc aagccagatg gactcaatcc
     7621 aacccaaatg gatctgtttt aagggcttat tttattcaag aaaggggcga agtctatgat
     7681 caaagctatt ttttttgata ttgacggaac attggtcacc aatcgttcaa aagcgttgga
     7741 atcaacaaaa caagcaattg aatatgctcg gaaaaacggc attttatgcg gtgtagcaac
     7801 ggggcgcagc ccagtaaaga tcaaagaaat cattgatgaa ttggaattag atatgtatgt
     7861 cgtgtataat ggtcaactgg tttttactgc agatcgcacg attatcgacc acccttttga
     7921 acaaaaagta ttggaacata ttgttgaatt tgcagatgag aaccatcgac aaatcgtttt
     7981 tggtgcgaga aatcggttag atggatcaac gacgatgcta ttaggacaat cgatttttat
     8041 caagcgacta gtcagctttt taccgcgtaa attcccggta cgtctgatga aaaaaatcct
     8101 ccaggttttt agccctcacc gacaaaagga tcgttatgaa acgttagaga tattaaaaga
     8161 accaatttat caatgtatat tgctcagtcc ggagtcagaa cagaaaaagt tagaacatcg
     8221 ctttcccgag tgtacgtttc agcgttcaaa tacgtatact gtagatatca tcccaaaagg
     8281 tggttcaaaa ttactaggca tccaagcttt cgcaaatgct gtcgaaattg aaatggaaga
     8341 aattatggca ttcggcgatc attacaatga tatcgagatg ctgaaaggtg taggaattgg
     8401 agtggccatg gggaatgctc agatcgaagt aaaacatgct gcagactttg tgactcaatc
     8461 aaatgaagaa gatgggatat acgaaggact gaaacacttc ggtctgattt attagtcaat
     8521 gaaagaagga aaaaatcagt atggaagcag agacaccttt tcaaaaagta gaaacattcc
     8581 acaaaacttt tgatccaaga agaccagaga tacccacggc ttttacagaa aatgaagctc
     8641 atacacgtgc tgcgttcaaa atagaagaac ttgttgaatt tgttgcagct acttcaccta
     8701 ataaagaaca actgcatgaa gctgttatgc tgctgcacga agcattagat aaagcagaag
     8761 aaaaaatact tggtaaaaca cagtggggaa gtgatccgct ggttgaacaa gtagatgcac
     8821 tgacagatat cctttacttt acttatggtt ctttttcatt actaggaata gtgcctgatc
     8881 gaatattcga aatcgtccat caggcaaata tggggaaatt atttccagat ggaaaacctc
     8941 attatgaccc tgtaacaaat aaagtgttga aacctgaaaa ctggcagatg gaatatgctc
     9001 cagaacctaa aatcgcggca gaaatccaac gtcagattca agaagcgatt gctaagaaga
     9061 aatccgctga tataggcatg tgcacaaatg aaaaagagtg atcagagttt cactattttt
     9121 gttatcttta tacgatggaa aaacaaaaga ttttcgttta agttagtgaa tgcatgaaaa
     9181 tagtatgcta taatctagaa tagatgtctt ttgcacgaga gacgtattat ttggatttat
     9241 gccaagcaga acgccatctg ttgcataaaa gatgcatact gaaaacggag gaaccataaa
     9301 tgggaaataa tgttatcatc ggaatcgtca ttgcaatcat tatagtcgcc attgtcgtct
     9361 ttttggttag ttacttgatg aagaaaaaaa accaagatcg attggatgcc ttagaaaaac
     9421 gcaaggaaga attatttgac ttgccagtga ttgaagaagt cgatgatgtt aaaaaaatgc
     9481 atctggttgg gcaaagccaa aatacctttc gtgaatggag tcaaaaatgg aatgacatat
     9541 ctacttcctc gttcgctgaa ctagaaagtc aaattttcga agtggaaaac ctcaatgaaa
     9601 gttttcggtt cttaaaagga aaaaaagcag ttgttgaagc agaagctaca atggaccaaa
     9661 tggagaaaca agtgacggaa atccgtgaag gtctaaagga attgcgggaa acggaagaac
     9721 gcaactcact agctgttcag caggcacttg acgtctatga agaactgaaa gaaaaagtca
     9781 gagaagacga gcatgaatac ggaccagctc tttttgaatt gcaaaaacag atcaaagtga
     9841 tcgaaaaaga atttacgcag tttgtgactt taaacacttc tggagaccct gttgaagccc
     9901 gcgaggtttt ggataaagca gaaaaacata cgtatgaagt ggaagctctg atgaaaaaaa
     9961 ttccaccgct gtatgaggag ctccatacca ctttccctga acaacttgaa gaaatcagtg
    10021 atacttacga gaaattgatg gaagaacaat atgtattccc agaagaagat cttgctgaag
    10081 atatcgcaaa agtaagtcga agaattgaaa attcattagc caatcttgaa aaaacagaag
    10141 ttgaaacggt cgaatttgaa aaccgtgaaa cagctgattt gattgattcg ttatatgata
    10201 tcttagaacg ggaaatggaa gctcagagat atgtaaaaac taaccaatca acgattgcag
    10261 agtatatcaa acatacaaca aagaataacc gtcaattatt gattgagctg gatcacacat
    10321 ctcaaagcta tacattgaac cacaatgaaa ttggccgtgt acgaggtttc caaaccgaag
    10381 tggaagaaat ggaacgtcaa aatgaacaga tgattccaca gatccgtcaa cacgaaattc
    10441 cttattcaga agtgcgcacg ttctataaaa cagtcttcaa agtcttagaa gatatcgaaa
    10501 agcaacaagt agagatcgac gactcattac atgaattgag aaaaggcgaa aaagaagcgc
    10561 aagaaaagat cgatacattc gaattcaaat tgcgcagttt gaaacgtttt gtagaaaaac
    10621 aacgtttgcc tggcttgccg aatgattacc tagaattctt ttttgttgct actgaccgta
    10681 ttgaagaact aagtgttgtc ttgaataaaa ttcgagtaaa catggaagag gtcaatcgtt
    10741 tagttgctct atgtgaagaa gatctagaat tattagataa gaagacacat gatttagtag
    10801 atgcagcagc attaacggag caaatgctcc aatatgcaaa tcgttatcgt catacacacg
    10861 aagaagtgag agaagcaatt gataaaagct actatttatt caataaagaa tatcactatc
    10921 aagaagcatt agacgaaatc ggtacagcat tagagcgagt agaacctggt gctttcaaac
    10981 gcatcgaaga tttttatttt aatcatccag acttagtata aagcaaaaaa gttagtaaac
    11041 cagcaagagc aagacggatt attgtcttgt tcttgtcttt ttttgtatat ttgaaaattg
    11101 aaacaagtga aaatttcacc tgctcttgaa agcaccttgg acaaccgtta taatagaaaa
    11161 gaatttcaaa aaagaggggt ttcttatgat atattttgat aacagtgcaa caaccccaat
    11221 ctttccgcaa agcttagatg catatgtaaa aaccagtcag cggattattg ggaatccatc
    11281 aagcttgcat gatttaggca atcaagctaa ccggttgttg cagcaagcaa gaaagcagat
    11341 cgctgatttg atccatgtag aaccagaaga aatctatttt acttcaggcg gaacagaagg
    11401 agataactgg gtattaaaag gaacgatgat cgaaaaaaga gaatatggga atcatatgat
    11461 catttcagga gtcgaacatc cggccgtcag cgagacagca gaacaattaa aagaattagg
    11521 aatcgaagta agtatcgccc cagtggataa acgcggattt gtacgtgtcg acgaattgaa
    11581 agaattaata agaaaagaga cagtattagt ctctgttatg gctgtgaata atgaagtagg
    11641 atcgattcag cccatccagg aaatcagtga tcttttggat gattttccta aaattcattt
    11701 ccatgtagat gctgttcagg cgattggaaa agtaccattc tcgcaatggt tgacagaaag
    11761 agttgatttt gcaacatttt cagctcataa attccatggc ccacggggaa ctggtttcat
    11821 ttattggaaa aagggtcgtc gtttagcacc attactgaca ggtggagggc aagaaagaaa
    11881 tcagcgaagt gggacagaaa atgttccagg tattgtggct atggttaaag ctttacgttt
    11941 atcattagag ataaaggaac aaaaacctga gcagacacaa cgcttaaaag tagctctaat
    12001 caatgcgttg aagacgtatg agaaagtgac gattttttca gaaggaactg actatgcacc
    12061 gcatatttta tgttttgctc taaaaggaat tcgcggcgaa gttctcgtcc atgccttaga
    12121 agaaaaacaa atatttgttt ctactactag tgcctgctcc tcacgtaaac atatggcaag
    12181 cagtacattg cacgcaatgc atgtaccaaa tgatctggct acatctgctg ttcgaatcag
    12241 cttagatgaa aacaattcgc ttgcagaagt cgagcaattt atgattattt tcaagcagct
    12301 ttataagaaa ttttctgcaa tcaattaaaa gaggagtgtt cttgtgaaat acagtgaaat
    12361 tatggtccgt tatggggaac tttcgacaaa aggaaagaat cgaaaaagct ttatcatgca
    12421 actagcacaa aatgtcagac aagctttgaa agactttcca gaaatcaaaa tccatgctga
    12481 tcgggaccgg atgcatcttt tattgaatgg cgcagacggg cagctagtta ttccaaaact
    12541 agcaaaaata tttgggatcc aaaatttctc tccaagtatt cgtgtagaaa aagatgtcga
    12601 agttttgaaa caagctgttc aagacatcat gaaagaaatt tatactggga aagaaacatt
    12661 taaaattatc gctaaaagaa gcgatcacca atttgaattg acaagtaatg aattgaatca
    12721 aacattaggt aatgctgttt ttgatatttt cccgcatatc caagttcaaa tgcgtcaacc
    12781 agatattcca ttacgtgtag agattcggcg tgatggcgct tatctatcgt atgaaacgat
    12841 caagggagct ggaggattgc ccgtaggaac aagcggaaaa ggaatgctta tgctttctgg
    12901 ggggattgat tctcctgtag cagggtactt tgccatgaag cggggagtgg aaattgaagc
    12961 tgttcatttt gctagtccgc cgtatacaag tgaacaagca ctgcaaaaag caaaagatct
    13021 aacagccaaa ctagcacctt atgtgggaac gatccatttt atcgaagtgc catttaccga
    13081 gattcaagaa gaaatcaaaa agtcagtgcc acaaggatat tggatgacaa ttactcgtcg
    13141 aatgatgttg cgtttgaccg atgaaattcg ccgtattcgt catggtttag tcattttgaa
    13201 tggtgaatca ttaggtcaag tggcttcaca aactttgcaa agtatggtgg ctatcaatga
    13261 agtaacgaat acgccaatca ttcggcctgt agcgacaatg gataaacttg aaatcattga
    13321 agtagcagaa cagatcgata catttaatct ttctatccag ccttttgaag attgctgtac
    13381 gatttttgct cctccacagc caaaaacacg ccctcaactg gaaaaggtcc atcaatatga
    13441 agagcgttta gcaatagatg aaatgatcca acgagcacta gctggcttga agatggaaga
    13501 gatacaagca gaatcgtcta atgaaaaaac tgaagaattt tcagaattgc tataagaggt
    13561 tatgaaaata gtgttttgac cagagtatta gagaaacaaa acgaaaaaat agctcgatgt
    13621 attttaccgt ttttgaacta atgtcgaaga ttagctgatt gaataccatt tatcaagaag
    13681 ttatggaaaa gccggttctt ttttactaac tgaaaaataa aattttattt agagatcaag
    13741 ctacagttga taaatgatat aaaaaagaga atttcccatg aaatagcgag gttgtgacag
    13801 aagtgggcag cttcaagaaa taagaaggaa tttacgaaaa ttgcttttca aatttttgtg
    13861 aaatttcggc ttatttttcg aagaagttac ttctggaaca ccgtgtatca gaggttgcga
    13921 aaaagctgcc ctgcatcaag taataagaac agccaaacaa aaatagttcc tcatatttta
    13981 cgtttggttg agcttattac cgcagatgca agcttttgaa caccgtttta tttgtctcac
    14041 acccttttcc ttcctacttg taaccttgct cccgtgttag aaacatgtta cactaaatat
    14101 gtgaaattat taacaaggag cgtcgttatg cgagaaaaaa cagatacact gccaaaagca
    14161 actgcgaaaa gattaccttt atatttacgc tacttgaaga tgctggatga ctcaggtata
    14221 agtagaatca aatcaaatga gttcagcgaa atcacccaaa ttccttctgc aacgatccgc
    14281 agagacttct cgcaattagg cgagctaggc agaagcggat atggctatga tgtccctttt
    14341 cttatcgatg tattcaataa tatccttaat actaaagaag aaaaacgaat cgcattagta
    14401 ggatatggaa atcttggcaa agcattgaaa cacaacaatt ttagaagaaa tgaaaatcta
    14461 aatatcgtgt gcgtctttga taatgatcca gcactgatca atcgagtaat tgatggagaa
    14521 atgatctatc cgattgatcg tttcgcggag atagccaaag caaaaaatgt gacagtagca
    14581 atctctacgg taccaagtaa atattcacaa tctgctattg atgaaattgt caaaggaaat
    14641 gtaaccgcta tacttaattt tgcgcctgac agagtaactg tcccagctta tgtcaatgtt
    14701 caatacattg atttgacaac cgagttgcag acgcttattt actttgatga gaattactca
    14761 gaagtttttt cttaggaaaa tttgagtagg cttattgatc ttgcgagaac tcgtcgtaat
    14821 tctttcaaaa attttttagt actaaatgaa gtggtttttt cacgaccact tgttgactaa
    14881 aaaaaaaaac cattgtagaa tgaagcataa cgctgaacaa gaggagtaac tggcacattc
    14941 attcttagag agagaactat ctgctgaaag gttctcaatg acaaccagtg aaggtagctt
    15001 gggagtttct gtcttgaatg gagtagagat agacgagtcg tgatcgttaa ctcacttgag
    15061 aggcaataat gattgattat tgcaatttag gtggtaccgc gtaaatcata cgtcctagaa
    15121 tacgaaagta ttttaggacg ttttttagtt taaaggagga aaacagcatg acggaagaaa
    15181 ataacctatc aacaaaatat aatccgcaag aagttgaagc tggacgttat cagcattggt
    15241 tagaacaaga tttgtttaaa ccgagcggag ataaaaaagc aaaaccttat tcaatcgtaa
    15301 tcccgccccc aaatgttact ggaaaacttc atttagggca tgcttgggat acgaccttgc
    15361 aagatatgct gattcgtcaa aagagaatgc aaggatatga tactttatgg ctgcctggta
    15421 tggaccatgc aggaatcgcg acacaagcaa aagtagaagc gaagcttaga gagcaaggga
    15481 tttctcgtta tgatctaggt cgtgaaaagt tcatcgatca agtgtgggaa tggaaagaag
    15541 agtatgcgag ccacatccgc gaacagtggg ctaaaatggg cttatcttta gattacagta
    15601 gggaacgttt tacattagat gatggattat ctgaagcagt acgtaaagtt tttgttacct
    15661 tatacgaaaa aggtttgatt tatcgtggtg aatatatcat caactgggat cctcaagcac
    15721 gaacagctct atctgatatc gaagttattc ataaagatat cgaaggcgcc ttttatcata
    15781 tgagctatga actagcagat ggatcaggcg tagtagaaat tgcgacaacc cgtccagaaa
    15841 cgatgttggg agatacggcg attgctgttc atccagaaga cgagcgttat caagcgctca
    15901 tcggcaaaaa agtgattcta cctttagtca ataaacaaat cccaatcatt gcagatgaat
    15961 atgtagatat ggaattcggg acaggtgtag taaaaatcac tccagcacat gatccaaacg
    16021 actttgaggt aggtaatcgt catgatcttc cacgcgtaaa tgttatggat gatgatggta
    16081 cgatgaatga actagcagga aaatatgctg gaatggaacg ttttgctgct cgtaaagcaa
    16141 tcgtgcaaga tctgaaagaa atcggtcgat tgattaaaat cgatacgatg atccacagtg
    16201 tgggtcattc cgagcggaca ggtgtcgttg ttgaacctcg gctgtctact caatggtttg
    16261 taaaaatggc gccgttagcg aaaaaagcca ttgataacca agaaacagat caagcagtgg
    16321 aattcttccc tccaagattc aatcaaacgt ttttacgttg gatggaaaat gtccatgatt
    16381 gggtaatctc acgacaatta tggtggggac atcaaattcc tgcatggtat cacaaagaaa
    16441 caggtgaaat gtatgtaggg atggaagcac cagcggatag tgaaaactgg gtacaagatc
    16501 ctgatgtttt agacacttgg tttagttcag ctttgtggcc tttctcaaca atgggctggc
    16561 cagatacgga aagcgaagat tataagcgat acttccctac tagcacttta gtaaccggtt
    16621 atgacatcat tttcttctgg gtaagcagaa tgattttcca aagcttggaa tttactggcg
    16681 aacgtccatt tgagaatgtc ttgattcatg gattgattcg tgacgaacaa gggcggaaga
    16741 tgagtaaatc attaggtaat ggaatcgatc cgatggaagt aatcgaaaag tatggagcag
    16801 atgctctccg ctggttctta tcgaatggtt ctgcaccagg acaagatgtc cgcttcagct
    16861 atgaaaaaat ggatgcttct tggaacttta tcaacaaaat ctggaatgct tcacgtttcg
    16921 ttatcatgaa tatcgaagga atgaccgtag aagagatcga tttatctgga gaaaaatcag
    16981 tggctgaccg gtggatcctt actcgtttga atgaaacgat cgaacgagta actgagctat
    17041 ttgatcgttt tgaatttggt gaagcaggtc gacaactgta taactttatc tgggatgatt
    17101 tttgtgactg gtacatcgaa atgagtaaag aagtacttta tggagatgat gctgtttcaa
    17161 aacaaaccac ccgtagcatc ttagtccata cacttgatca gatcctacgt ttattgcatc
    17221 caatcatgcc attcgttaca gaagaaatat gggaacatat tcctcatcag ggaaattctc
    17281 tagtagtggc agaatatcct gttgtacgtc cagagtttga tgatgaaaca gcttctaaag
    17341 ggatggaagt attgaaagaa ttgattcgag ccgttcgaaa tattcgttca gaagtgaata
    17401 caccattgtc taaaccaatt acgttgctaa ttaaaacaaa cgatgctaaa atcgatcaat
    17461 ttttagttga aaatacaagc tatatcgaac gcttctgtaa tcccgaagag ttgacgatat
    17521 caagtgagat cactgcgcca gatctagcga tgtcagctgt tctgacaggt gcagaaatct
    17581 tcttgccgtt agcaggattg atcaatattg aagaagaaat caaacgatta gaaaaagaac
    17641 tggaaaagtg gacaagcgaa gtaaaacgtg tccaaggaaa actttctaat gaacgttttg
    17701 tttctaacgc gccggaagaa gtagtagagg cagagcgtgc aaaagaaaaa gattatttag
    17761 agaagcaaac ggctgtcaaa gaacgaatcg aaagtttgcg tactattcaa taagaataga
    17821 aaaagagagt gtgaaatcag ctagctatta ctaaaagcta gctgattgaa catcgttaca
    17881 ggaaagagtt tgagcctcac tcttagcttc gattcataag gagatgtgac ataaattttg
    17941 tcgcatctct tttttagtct actcttatta tgtaggagaa ggagggaggt ggatcatgta
    18001 tcaagagtca ataaagtagt tgataaaatc gttcctctct ctgtttcttt tctctttgtc
    18061 atacttttat ttttcttatg tgttctattt gttataataa aagagaaatg ggggaattgt
    18121 tgatgacgat tgaagaagca atagaatgga tccatagtcg attaccattt ggttcacgtc
    18181 ctggccttga ccgagtcgaa gctttattag aagtggtagg gcatccagag agaaaagtaa
    18241 aaacgatcca tatcgctgga acaaacggaa aaggttctac tgtagcttat ttgagaagcc
    18301 tattagaaga ggctgggctg acagtaggta catttacttc accttatatc gaaacgttca
    18361 atgaacggat cgcaatcaat ggcaaaagca ttccagacaa tgatttgatc cagcttgtaa
    18421 aaaaatatca gccactgatc aaacaacttg atcaatttga agcagtagct ggtattactg
    18481 aattcgagac attaacagca atggcatttg attatttttt gatgaagaaa gtggacgtag
    18541 cgattatcga agttggctta ggcggcttat tggattctac caatgtagct gtaccaatgc
    18601 tgacgggaat aacaacgatt ggacttgatc ataccgaaat acttggagat acaattgaag
    18661 aaatcgctgc acaaaaagct ggaatcatca aacaaggcgt tccagtagta acaggaaata
    18721 ttgccccaga agcttttact gtcatccaac aaacagctaa agcaaaaaat gcaccgcttt
    18781 atgtatacgg ggaaaattat aaaataaact atctgcatcc tgatgagatg tggggagaag
    18841 tatttgaatt ttttaatgaa ataggaaaga tccctcaatt aaccactccg cttttagggc
    18901 aacatcaagc tgaaaatgca ggagtagcca tcgaattgta ttttgtttac tgtcaattgg
    18961 aaaagctgcc tttccgagaa aaagatgttt tgaagggatt gaagaaatct cgatggccag
    19021 gaagaatgga gcgtttgagt aacgagccat tagttgtttt agatggtgcc cataatacgc
    19081 atgcaatgaa ccggcttgtt gagaatttga aaaaagaatt caaaggatat caaatcaaca
    19141 ttttgttttc cgccttacga actaaaaatg ttagagaaat gctagaacga ttgcagcaag
    19201 taccaaatgt ccatatttat ttgacgacct ttgaacatcc aaaagccatc gaattaagtg
    19261 aagtatcaga tttagcaagt gagagagtat caatcgtttc attgtggcaa ttcggattag
    19321 cagatatatt ggaaaagatg acaaatgaag acgtattagt tgtgaccggt tcactttatt
    19381 tcatttcaga agttcgccat ttattaatac aattaggagg agatcatgaa gtataatgca
    19441 gtgatttttg acatggatgg tttgctgttc gacacagagt tagtgtatta cgaagccaca
    19501 caagtagtag cagacaagat gggttttcct tatgataaag acctgtattt aaaattctta
    19561 ggtgtttcag atgaagaagt atgggcgaat tatcatatga ttttctcgga atttggcaaa
    19621 acaagtgtac aaagattcat agatgattca taccaggaaa cgcttgaacg tttttcgcaa
    19681 ggagcggtac aaatgaagcc cggtgtgttg gaactcctct cttttttaga agaacatcag
    19741 attcccaaag ttgtcgcttc cagtaaccaa cgagcagtca ttgaactttt attgaagaag
    19801 aacaatctgt ttgaacgatt tgagacgatt gtttctgcag aaaatgttca acgagcaaaa
    19861 ccagacccag aaattttctt gttagctaat cagaagctag gtacagcgaa gaaagaaaca
    19921 ttgattttag aagattcaca aaatggtatt ttagcagctt ctgcggctga gatcccggta
    19981 gtcatggtac cagatctgct tccaccatcc caagaattga tcaaaaaaac agctggggtt
    20041 gtttcttctt tacatgaaat ccctgcattg ttaaaataaa aatccatctc ttttcgtatc
    20101 ttattttaga taagatagaa aggagatgtt tttttgggaa aacgattgat caaagaagta
    20161 cctactagct ctttaccaag ggaacgtatg gaaatttatg gcgcggaagc tttatcggat
    20221 caggagcttt tggcaatctt actgcgtacc ggtcaacacc cttatagtgt gatgtcgatt
    20281 gctggaaatc tgttaaaaac gtttggagga ctggcctctt tacgacaggc tactttgcat
    20341 gagttagaag agattcgagg gataggacgc gtgaaagcaa tcgaaatcaa agccttgatc
    20401 gaattaggtc gacgaattca gacggatcat gaaagagcgg ctccaccggt tcgtaccagc
    20461 tacgaattgg cccagcaatt gattctggaa atgaaagatc acaaacaaga acatttggtt
    20521 tgtatttatt tggacacgaa gaatcaagtg atcttaaaaa aaacagtgtt catcggttcg
    20581 ctgaatcagt cagtcgctca tcctagagaa attttccatt atgctgtacg ttattgtgca
    20641 gcaaggatcg ttttagcgca taatcatcct tccggaatat ataagttagt acacataaat
    20701 tatataagga aatttactgt tatattgcca tctggaaata ctattatgtt atcgataatt
    20761 gaacgccata atgcattttt ttcttcttcc gaagattctt tataaatttc atcgaattct
    20821 tttgatagaa taaattcgac attttttata tctattttag ctggctctac ttcaatttca
    20881 tttaattctt tcattaaagc ttctcgatct tttttgtatt cctctaagtc tataacttca
    20941 ttcaagtagg ctttcttcaa tctatctaat ttattctcaa tatttttctt actatttttc
    21001 tttttaataa tctttggttg tttttttgaa tagtttattt gtatttgttc aaatttttgt
    21061 ttagtagctt caaaaatata acgttctaaa tttttttcgt aaaaagcgcg cttatttgtg
    21121 caacgtaatt tattatttct tcgttttaca catctataac aagtcctttc gtatatagat
    21181 tctgtaccgt cttttttctt atatcttgct ttaatagttt gaccagctac tgatccctga
    21241 cagtcagaac attttaataa acctttaaaa atgtaatcac gttttgcatt tgtttttaaa
    21301 tttttaggta aggctttttg aacagcataa aaaagttttt tatcaataat aggaggacag
    21361 taatttttat tatttcttaa ttcaccaatg tattttttgt tcgtcaacat atttttaaca
    21421 ctttgataat ctctaacgat tccatactga gagcctaaat aataaacagt ttttcttaaa
    21481 ctaccactag aaagaaagta gttgaatata tctatcacga taggagcatc atcatttatt
    21541 actaatttct tattttctat agagtagcct aacggagttt tcccgcttac tacttcacct
    21601 tgtgcaattt tatttgccat aacagctttg atgcgttctg aatcaatttg ggcttccaat
    21661 tcagcaaaac tcattacttg tgcaatgaaa gttctgccat acgctgtagt tgtatcataa
    21721 tattgttgag aaacagcatt ccaagaaaca ttgtgttttt ctaaaatttc ttgagtgttt
    21781 aaataatgtc gtagatttct aaaccatcta tctaattttg taaataaaat tagatctatt
    21841 ttattttctt ttacatcttg taatagtttt tgaaattcat cacgatttat tttttgacca
    21901 gaaataccac cgtctacata ttcattaact actttcaaat ccttgtgttg ttcgatatat
    21961 tcatagaggg tttctttttg ttctctaaga ctatctccat gtttggcttg ttgttcagtt
    22021 gatactctca tatataatgc tactcgtttc atgttatctc ctttcgaatg tatgttctta
    22081 tcgttgtaaa agaaaagccc gaaggctaat ctttttacta cacatctgtt aattctaatg
    22141 atcttctgta ttgttcagct tgagctagtt tagtaaaaga tacagttccg ttataatttt
    22201 ctaaaacaac tttttcaatt tcatcaagag atactttaaa gaattctttt cgttgattaa
    22261 ctttattgac ttcgtttttt ctaaaatgcg aatgtagttg attttctaat gttggtgcat
    22321 cttctgaaaa tatcattgca tgaacatcaa attcaaaagg tacagaagcg ctactaagtt
    22381 ccttaattct atccataggt tctaaccgtc tagtcattcc tattttatag acatcttcac
    22441 cgaaagatcc gatattactg atgacataaa catagccagc tctagtatta agttctcttt
    22501 gcaatacatc ttctttgaca gtttctagtt ctcttaattt ctcttccagt tctttaattt
    22561 tatcagcata gagttctttt tcaacatcag cactagcttt ttgcatgtat gccattaact
    22621 tagttatctc tgagttaaac tgtcgttctt ctttatcaat gcgtttcttt tcacgttcta
    22681 tttcacgtct taccttttct tcttcaatca tttgttcttt tattgctttt tgctgttctt
    22741 tttcatcgtt aactttaact atgtatgaat agttgagttc taattcttga agttttaatt
    22801 caagtaattc ttttttgaat tctgcttcat cgtttttaaa aagcttgttt attttatcaa
    22861 aagttcttat aattttttct ctagttgaat ctacgttaga aatagtaagt ttattgagaa
    22921 gtccagttat ttctgattct aatggtataa gcattttctt tttaatatta ttagcttctc
    22981 tattattcaa ataagaagga atattaattg caccgtctaa aataaaatcc ttttctttaa
    23041 tctttaataa agaaagtttg ttttttattt cggatgaaga agtttcatct atattcggaa
    23101 taattactga tttatagata gtgaccagag atgtgtcata tttttgatta atttcatcgt
    23161 ctaaccgctg gctttcagca ttaagaatat caattttgtt ttctagcgtt gacaagtttt
    23221 tattcaattt acttatgttt ttctcttttt cagatataaa cgtttcccta gcatttaatt
    23281 cttgagaata ttcctttacc ttactctcta aggcagaagt tttatctttt aattttttag
    23341 cttcagataa tttgctacta cccataatta ttaaaactat tccaactaaa aacaatagta
    23401 ctcccattca aaacgcctcg cttcttttat aaaataattg tcaaaatcat ataaaccctt
    23461 accgaagttg acggctccgg catgggaatt tttttaaaat acaacttttc cgataattct
    23521 aatctgttct ggcgatacaa ttctatcttc gtataagtcg tttatagaac gtaaaatgat
    23581 tgtttgattt tcgtaatctt tatatatctc tttacatgta actccgtcac cacctaattc
    23641 cacaatagca atttccccat cttctacgtc cggttgttct ttaacgaata cgaattgtcc
    23701 attcctgata acaggttcca ttgaatcgcc tataataggt actgcgaagt cagcagcact
    23761 tggaactctc tcaaattctt cctcttcgac aaccgtatca ccgtaagtaa gttctgttgg
    23821 attggcagcc gaagccgaat tgtgaacagt tgggattttt tcttttttag gaaaatctag
    23881 gacattttct tgtttttgtt cttctaatcg attacttgca aattcatagg tagcaacttt
    23941 attttcgtcg ttaagctgat tatatatagg aaggatatta tatatctgat tagatataga
    24001 taaatcaata ttcatcaaat catctatatc aacattgaat atcttagcta tctcatttaa
    24061 ggtttttaat tttggtgtat attttccttt ttcccattcg cttattgagg atgaactttt
    24121 tcttcctagt ttttcggcta gttcttgttg atcaatatta tacttttctc taagaaactt
    24181 tagattttca gcgaacatag taacacctcc ttgagttaat tgtaacaccg tttcggaaaa
    24241 aatgtaacag gtttcttaga aaatatttta gtgtttttaa agaagtattt acgcaaaata
    24301 gaaatcgatt tcaggaaaac tgaaatatgc acttgacttc ggaaaaaccg aagtatataa
    24361 tttagtcaga aagttaaaga gaggaggcga ataaaatatg gataccgcga agaaagaaaa
    24421 atatacattg agacaattaa gagctttaaa gggttattca aaagaagaac tgtcaaggaa
    24481 aagcaaagtg acatcaagaa caatatttat ttacgaaaac gatgtagata aaatgaggaa
    24541 cggaaagtac gccactctag aaaaaattgc taaggcattg ggtgttagag tttccgatat
    24601 ttttttagac cctgattcgg aaaaaccgaa atcaataaca ggtgaaacaa aacaagtcag
    24661 ctaggaggtg tgaatagtgg aagagaagaa tataaaagta ccgactcttg aagaatatac
    24721 aaaaattgtt gtcgaaacag acgagcagaa cccgaaaaca atcgcagtta ttacggcgaa
    24781 tgatattgaa tcatgcgaag gttttcgagt tcgaatgacc cctagatatg attaatgttc
    24841 tttatcacgt ggaggtatag gatcgtttcc aaaactatct tttgattgta tttgtccatt
    24901 ctttttttgg acaataaact ctgattgctg ttttttagaa atctttttac catactcaac
    24961 agcatctgat ttattatcaa atagttttgt atcttcggaa ttaccttcac cacgtacagc
    25021 ccatttgcca tttctaggag atacccattg atttttaccc ataacaattc acctcgcttt
    25081 caagttaatt ctattaagag gtgaaaagaa aacaaactga tggaggtgag attgtgagta
    25141 acaagccaaa aatcactttg aatggcacac ctaatcttca aagattagca gatgaaatgg
    25201 ctagaatacg ttctagacat tggggagtta ctgtggtggc aaccataatt gaacaaaaag
    25261 aaaagcccac acagccggca agcaagtagt gggcaccata gaacaataat attatatcac
    25321 acactcgcca cttccgaaaa gaggagttgc tgctctcctt tcaagtttgc caaagtccac
    25381 gtttcttcat tttggcaact cctcttcttg gaggtggtga cggcgagaga cgaaggaggg
    25441 atgacatgaa ggaagaatca aaaataggga ttttgaatga gaacaattac acaagattaa
    25501 ttattgaaac agaagaaggg gaaaaagtag cagaagttac attgaccgat gcaactcctg
    25561 ctgacggtta tcgtattcga ttaactccta aatatgatta accttttggt gggtgtggat
    25621 cgtttccgtg actatcacgg ctttgaattt ttccatctct gccatgaata aatagctcag
    25681 atccttgatt tttagaaatc tctctagcga tttttactgc ttctgatttt gtattagtat
    25741 gtgcagtcgc tttagaattt ccagcacctt tgacattcca accaccattg gaattaggta
    25801 caacatgttg attttttccc atagttttca cctccatttc tatagaaata ttttatcaaa
    25861 tagaaatgga gaaattcaat aaacgaaagg agggatcaaa tgacattaca agagcatcaa
    25921 cacttgatgc gaaaactaaa tcaggaatac cacgaggaaa tgaaacctag attgctaggg
    25981 gaacaatggc gtgaacgcca gaagaagtgg ttagaaataa aaaagtgact cagccgtcca
    26041 aagcaatgag tcacaaacca aaaattatac ctaaggagat tttatcacat gaataagaaa
    26101 attgaaaatc ttatcgaaga attgaaacgt gaatgccaaa agcaaggtgt ttctattatt
    26161 tgtacagccc aaaaagaagg ggaacttaaa agtctcgttt atggtgagac aacagaaatt
    26221 ttactttgtc ttgctatgca agaagaacat ttagatgaaa atctcccatt gtcagcacat
    26281 attatgcgta gaattgctgt ggatgcttac gaacaagcga aaaatgaaga agaaaatcaa
    26341 ccttcaaatc atacttttgt tattaataac aaggaagatt tagctgatgt gatgactcgt
    26401 attctcaagg gggaatttca atgatgaatg aaaaaacaat tgatctactc attattttat
    26461 ttttcacgtt agtgattgta gcgaaaagtt atgtaatctt tggcttgtta ttcgcaatta
    26521 ccatgcttgt gctttgcgtg ttagcaagca gaaaagaggt taaacatgaa cgagttagca
    26581 aatcttgaca actatttaac tgatcctgat tatgctaaac caccatatga agcgccaatt
    26641 gatgaggagg atgaagatga gtaaatctac cttagaaatg agccatcaag aatggctcga
    26701 agaccgcaaa agaggtattg gtggctcaga tgttgcaacc gtacttggat taaacaaata
    26761 caaatctcct tatcaattgt ggcttgagaa aacgggtcaa attgaattga aagatttaga
    26821 aagcgaacca gcttattggg gtaatgtttt agaagaagtg gttgctaaag agtttcagga
    26881 acgtacaggc aaaaaagtac gcagaagaaa ccaagtattt gaacatccat tacatccatt
    26941 tttaagagca aatattgatc gggaagtagt gggagaaaat gccattctgg aatgtaaaac
    27001 agccaatcaa tttctcggaa aagagtggga aggtgaagag gtaccgctta gctatctctg
    27061 tcaagttcag cattacatga acgttttaaa caaagactat tgttatatcg ctgttttgat
    27121 cggtggacaa aaattcattt ggaagcggat tgaacgagat caagagctga tcgatacaat
    27181 cactgaacaa ttagtagagt tttgggaaac gaacgttctt ggaggtatcg agcctgtaat
    27241 tgacggaagt ggagcgactg ctgacttctt aaaagaaaaa tatgcagatg tagaagaaaa
    27301 tcaaacagct ctaccatcac gttttgatga acttatcgag caaaaaagag aactcaagcg
    27361 gacgaaaaaa gaaattgaat catctattcg tcaagtagac aacgagatca tcagtgagct
    27421 aggtaaacgt gaagccagta tcggtatcac acaaagaaac attatcagct ggaaacttgt
    27481 tcgtacaaga cggatgaaca cgaagaaact agcagagaaa tatccagatg tcgcaaatga
    27541 tgaagagatt tataacgtta ctgaatcaag aaggctaacc gaaaaggaga tcaaataata
    27601 tggcaacaaa tgaatcgtta aaaaatcaat tggcagaaaa gccacagaaa caagttgcac
    27661 caggacagtt agggcttaaa gctctaatga atacaccaac aatgagaaag aaatttgaag
    27721 aagtacttca tgacaatgct aatgctttta tgtcgaatgt tatgactctt gtatctaatg
    27781 acagttatct tgcagatagt gaaccgatgt ctatcatgag tggtgcgtta actgctgcaa
    27841 cattaaatct tgggctagat aagaatttag gttatgcata tttagttcca ttcaatagta
    27901 aaaacaagca aacaggaaaa tgggaaaaga aagctcaatt catgcttggc tataaaggat
    27961 atatccaatt agcccaacga tcaggtaaat acaaagcatt aaatgtgatc gaagtttacg
    28021 aaggagaact aaaaagctgg aaccgactga cagaagagtt tgagtttgat ccaaatggta
    28081 gaacgtctga tgaagtcatt ggatatgttg gctatttcga gttactgaat ggattcaaaa
    28141 aaactgtcta ttggaccaaa caagaaatcg aagctcatcg gattgctaac aataaagatc
    28201 gcgataagac aaagttaagt ggtgtgtggg catctgatta caatgcaatg gcacgaaaaa
    28261 ctgttttgag aaatcttctt tctaaatggg gaatcttgtc catcgaaatg caagaagcca
    28321 ccacatcgga tgagagagtc caaagggttc aagaagacgg cagcattatt gctgaaacag
    28381 aagttgaaga agatattcct gaaagaaaag aagcagaggt tatatctgaa gaaaatgaag
    28441 atgtacaaac tggattattt gatgcatcta atccgccgtt aaacaaataa tgagggagct
    28501 ttctcccttg cttttctaga ggagaaatac gaatgaacac aggatatgtc aaattacatc
    28561 gaaaagtgat gaattcattc gtttggacca atccttatat gtataaatta tggagcttgt
    28621 gtttgatgaa agcgagtcat gagaatcgca agatactttt taatggaaaa gagatacaag
    28681 tgaacagcgg agaattcgtc acagggcgcg atgctatcac atctgagatg aacgaaggcg
    28741 tgaaacgtga acatcaagtg aacagcggtt ctgtatggag atggctaaaa caatttgaaa
    28801 aaaacggaat gttgaacatc aaatcaacta cgaaatacag cgttatatca ataaaaaact
    28861 ggtctttgta ccaaagcagt gaacaacaaa tgaacatcaa acgcacaaca agtgaacaac
    28921 aagtgcacac aaacaagaat gaaaagaatt ataagaatga aaagaataat aaaacatcat
    28981 cgtcgcaacc acgcaaaaag cgtgtttacg acaccgactc agtttactac attctcgcgg
    29041 aggagttatt caaacagatt tgtcagaatc aggaaatcaa aaagccgaat ctgcaaagtt
    29101 gggcagataa cattcggaaa atgatcgaga tcgacaagcg gaccgaaaac caggtacggg
    29161 gaatgattga atggagtcag cacaatgtgt tttgggcatc gaatatttta tctgctaaaa
    29221 aattgcgaga aaaatacgac acaatggcag cgcaagcaaa tcgtgattat aaaacaaaac
    29281 aaactaaaac gcttgaatac gagaaattta gcacagatga gttgcctatt tgagaggagg
    29341 cgtaggcatg gaaactgttg gggaaatcat ggaaaagctg atacagaaag tgcttgtcca
    29401 acgtggcgaa tgtcctgaat gcggacagcc tttgtatgga tggcgtacga agaaccctga
    29461 tggctcagaa cgttgtaagc caacctgtat gcaatgtggg tataaagcat tgcgagttca
    29521 ggaagactta caaacagaac gaatttacaa cgagagcctg aaagcaagag caatcaattt
    29581 tttcaaaggt ggttctgttg tgcctaatca agcgttgttt gattgcacat tgcagaatta
    29641 tcaaattgtc gatcaagaaa caagacaagc ggttgaagta accaaacgct ttgttaattc
    29701 agtcttgtta ggaaatccaa gtcaccttgt tttaactgga aaacaaggaa caggtaaaag
    29761 tcacctagcg atggcagcgg cttgggaagt cttgaagcga tcaaactacg ataaaaaaat
    29821 cttatttatc gggttacagg aaatgctgga tcaaatcaaa ttttcgtaca acaatcctga
    29881 actcagaaaa acgattgagg gatcgttgat tgcagatatc aaaacagcgg atttagtcat
    29941 cattgatgat atcggttcag aactaggaaa agatgcatca gatagtcgag cgtttggcat
    30001 aaacacgcta aattcgttct tggatgcacg acagaaccta gcaacgatta tcacaacgaa
    30061 cttgcttggt gaagaactga aaaaagctta cggtacgaga acaatatcaa gaatgtttgt
    30121 caactctgat ggatttacga tggtattttc tcaaacagca gacaagcgca taaaaccagt
    30181 gaaaggtagt atcgcatgaa taaataccgt aataaaaaaa ctgttcatcg aggtatcaag
    30241 tttgattcta tcgcggaagc agagtattac gatctagcct tgtggcaagc tgaagcgaat
    30301 ggttggaaag tgaagctcca ggaaaggttt gagctgatgc cgaagtttga actagagggc
    30361 aagaagtatc gcaagatcga gtatattccc gacttcacat tttacaaaag cggcaagctg
    30421 gtcaaagtcg tagatgttaa ggggatgcag acaaaagact ttaagatcaa ggcaaagttg
    30481 ttctgtcatc aatatcaagt gccgttgata ttagccaaaa aatatcggaa tacgttcaag
    30541 gaagagcgtt tttaacgagg tggtccatca tgacaacaga agaagtgatt caaatgcgaa
    30601 ttcgaagcct tcggcgtgag attgacgatc tggaacgaac aaaggcagtg atggtcaatg
    30661 aaacggctag aaaggcaatc gatttgcaca tagagaattt aagaagggaa atccgtagat
    30721 tggaggaatg agcgtggata aggaagcggc ttggcgaaaa ttaatgttgc tgattcaaga
    30781 tgagaactgg caagaagatg aagcagtggt tgctgaagtt cagcgtctag gaaagattgc
    30841 taacggacgt atacgaaaaa agccagacaa aagaaaacag cgcaaaggga aaatcgtcgt
    30901 tgttttacac gaaggcaaaa ttttgatgca aggaacagct agtgagctgt ctgcagaaac
    30961 tggatatacg cgtgggacta ttcgaacgta cgcttggcga aatcacaccg atcgaaaagg
    31021 gcacgaatat aagtatttgg aggaagaaaa atgaacgaaa acaaattaat caaattgggt
    31081 gtagcaggag cagtaatcgt aggtattgga gttatcggag gatttaagtt cttcgaaaaa
    31141 atcgataatg gatatgtggg tgtgcgctat tcaatgaacg gcggtatcaa agatgaagca
    31201 ctgacgcaag gtgtgaaatt tgtagggatt gacaaagtga tccaatatcc aattcgcttg
    31261 caaactatcc aatcaaaaaa tatttcagta tctacaagcg acggcaaaaa gacaacgatt
    31321 gatatcaaat atgactacaa agttgattca actaaagcag caaaaatgta caaggaattt
    31381 gggaatatca cttcggaaga tatcgaaagt ggatggttaa aatctaagct tcaaaaggtc
    31441 gctcgtgaag tttatgcgaa atatagtctg cttgatgtcc tttcaggaga ttcctctaaa
    31501 gttgaagctg aggtattaac gaactttgct aaatcagttg aatctaaagg gtttgaagtc
    31561 gaagacgtaa cacttggtgt tccagatgtc gataaagaaa cacaaaaatc aatcgatgcg
    31621 atcattcgag ctggtcaaga aaatgaaaaa gcgaagctag acgcagaaac tgcaaaaact
    31681 caagctgata gtgaagctta caagaaaaca aaagctgcag aagcagaggc agaatctaat
    31741 cgcaaagtcg ccgaatcagt aacagacaat ttgattcgtt atgaagaagc tcaagctcgc
    31801 aaaaagcatg gatgggtaac agtaaatgga gcagatactg tagttacgga tgaagcaggc
    31861 aaataatatg ggattcttta tggctaaaat tctcttgttc ttaggtttag taggagcagc
    31921 atatctcgtg tatgcgctcc tttcccaaac tgatgacaaa gaagatgaca acaacgatga
    31981 aatgaaattt taggaggaga aataatggac gaactaatca caaaagtaga gcagtgggct
    32041 aaagacaagg gactggatca agcagatcca aaagcacagt ttttgaaagt agctgaggaa
    32101 ttcggggaaa tagcttcggc gatggcaaga agtaatgatg aactatttaa agatagcgta
    32161 ggagacgtta tcgtcacgct gattatcctt tccatgcaaa aagggacaaa cgtacaagag
    32221 tgtttagaaa tggcatacaa cgaaatcaaa ggacgcacag ggaaaatggt agatggtgta
    32281 ttcgtgaagt cgagtgattt ggaggatgtg aaatgaaata cgaaatacca ctaagtgaag
    32341 cgggcattca agcaattatc aatggtcggg aggttaacat agaacttcct gatggtactg
    32401 aattagtcat cagacaaagt tatttgaaag atatggcagc tccagtatta attgatcgtt
    32461 ttaacgtgac tgattctgtg gtagagaacc acttaaaaga atttcgatca agtatagaca
    32521 acactttcag attagggagt tgattgacaa tgaacaccag acaccgcaga gtagcaaaac
    32581 taagaaaaca ggaactaaat gtactaaaga caaagtttga aaaagaatat ggaatttcag
    32641 cagaagaaac atataaagtg gcaagtcagt ttgttgctga tgcaagtgat gctattcgta
    32701 agtttgggat ttcgatatta aatgatgatc gtaaatggga ggaaatgaga tgaaactaaa
    32761 agacggattt tacgctagca gtcacggtat cggcggttta atgctagata tgccgacaaa
    32821 gaaccctaaa acacgcaaga aatcaaaatt caaagtcggt gacatggtcc gctgtgaagc
    32881 agaagagttc gtttatccgt tcagaggata cgttaaaaag atactgtcaa actcagcaat
    32941 cattcgtatt gaaaatacaa tgaagtgtga tcgttcgact gcaaaacaca agcattattt
    33001 agctgtagcg agattagttg acatggaagt aatcaagagc aaataaaaaa agccggatcg
    33061 ctccgactga ttcaataaat ccaacacatt tattatatca cataaaggag cggtttgact
    33121 tgatgcaatt gttacgagag gtagatttca aacagacaag atgtaatgcg agagatgtgc
    33181 tgaagaactt tcggcgtttg gagcggatgg caggtcgctc tttgatagat attaagtcgc
    33241 cgattataac ggatatgccg aaggcaccga agcatggcaa taaggcagaa gacgcgatta
    33301 ttcagatgat ggatatagaa acggagagag atgcgattct agcggctttg atggctctta
    33361 gtctgattag tcgtcagata ctctactaca gcttctgtgt gccagatagc ttctcaaact
    33421 acaggattag ccgtgaagtg ggttattcag aaagaagcat acaaaggatg aagtcggaag
    33481 ctctaataga gtttgcagaa gcgtataaac acggaagaat aattgcttat aaataggggg
    33541 accatataat gtggaaagat tatgtatcgt tgaaagagtt gaaaaaagat cttgttttca
    33601 aaagaattgt agaatggtca gagagtgaat taattttaga agatggaacc aaaatggaag
    33661 ttgtatgtag cgaatcagat tgctgcgcat gggccgaagg tgaattcaaa aatgtaaagc
    33721 ttgatgcagt gattacagat ataaagattt ttgataaagg taaccgtctc tataatggtg
    33781 acggacatac ctcttatgct gaagtcgttg tttatcataa tcgtaatgag atcgctaaag
    33841 cagaatgcac agcgaatgat gggaatggcg gctactatta tagtgtttgt gctttaaagg
    33901 tcaaagacaa actttgtata gtgactgacg cataaaaaaa tggcggtttt ttggcggaat
    33961 gatggcggtt tttagccatt tatcagtgat attatggtag tgtcgaaaga ttagtgatag
    34021 gtctgagaca aaataataat aaaaggaaca tcgttttatt attgtttcac aattaagctt
    34081 cgatagacag caacggaaat attaagaata aggatgtgaa ttttaactcc ttctaaattg
    34141 ttcttattat ctatcatccg ttgctgtcta ttgttacata cagatcgctt aggcggtctt
    34201 tttattttgg ccgaaaacct acattttcga tggccgatta ttggaggagg aatagcatgt
    34261 tcaaactatc tgaaatcatt aagaagtccg acgttgagaa attagagatg ttaaaaaaga
    34321 agttgaagaa atagcagtct cttcgtgagg ctgttttatt ttgctcacaa aaatagacca
    34381 ctatcgggta atagtggtca ggaattaaat gaaaaagatg ttagggttgt tagctaagta
    34441 taacatcata acgcttacaa aacaatgcaa gaaggataaa ttattatgag aacttactgg
    34501 tatgtgtcat taaacaataa atatccgaag ccaatgaaag gacagcatag gcgtgtagtc
    34561 atgtctgttc aaatgaaggc gaagtattcg attgtagaaa tgatcagaga ggcaacgcca
    34621 gtagagattg attattgcaa gctagtctat tgtgggtgcg gccgttggaa agaggatcat
    34681 gtacaaaaaa atatcagcaa gtacatatag agaggcggtg attaaggatg gaaaaaagcg
    34741 atacgaaagc gaacagatac aaacctactg ctgcagagaa aaaactcttg gaagtattga
    34801 taaatccaga taacttaggc aaaccggtgc aagagttgtg ttcactggcg aaaataggta
    34861 ggaccaaata ttacgacgcc atgagcaaag atggctttgt tgatctagtt aacgaaacaa
    34921 caatggatct gatcaaagga aaagcttctg atgtccttaa tgccacttac aagtatgcat
    34981 tgactgaaaa aggtcatcag gataggaaaa tgattctgac tattgctgga atctatgcag
    35041 acaaacaaga actcaaacat tctggcggcg tcgatatccg aaaacagtat gagaaaatgt
    35101 ccgatgaaga attagaagag ttggtgaaac ggtatgaaaa aatcaacgac tcttaatcgt
    35161 gttgagtatg ccgttgttca aagagagcta gccattcgaa aagctaggaa aagtttttgg
    35221 ctattctgcc agcttcttta tccagagttt tacaaagatg atcggttgta tttgaaagat
    35281 ttatgtcata cgctacaaga tttttacgaa gataaaatcg acaaaaaaat tttggttatt
    35341 aacatgccgc ctcgacatgg gaagactttt acagcgcggc tattcgtttt atggatgttt
    35401 ggacaaaatc caaagacgaa aattattacc ggatcttata accaaatcct gtcatcttta
    35461 tttgcgcaac aaacacgtga tggaatcatg gttgaaaacg aaaatgttaa ggctgaatac
    35521 tttaaagata tttttccaga ggtgcaaatc aaatatggag atgctgcaaa gggtttctgg
    35581 tctttagatg gttcagaaga aaagaattat ttagcgactt ctcctggtgg aacatccact
    35641 ggtattggcg cgaattatgt aattgttgat gacatcatta aaaccgcaga agaagcctat
    35701 aacgagcgtg ttttagattc tcactgggaa tggtataaca acacgttggc ccaacgaatg
    35761 gaacggccac gtaaacagat attgattatg acacgttggt caagtaatga tttagccgga
    35821 aaaatgttga cgagacgaaa aaataatgtt catcagatct gttataaagc agtacaagaa
    35881 gacggctcga tgttgtgcaa cgagattatg acccacgatg agtacttaga tgtggtacaa
    35941 gaaatgaatg tagatattgc agaagccaac tatcagcaag aaccaattga ccaaaaaggc
    36001 aggctatatc agaagtttct tacttatgat acgttgcctg ataacattat caaaatatgg
    36061 aactacaccg acaccgccga caagggtgcc gattactttg cgtctcctgt ttttgctgag
    36121 acgtctgatc atgatgctta tattatcgat gtcatgtata caaaagagcc gatggaaaca
    36181 actgaaatag cccacgctaa tatgattatt cgcaatcgag ttaataaggt acggattgaa
    36241 ggaaacaatg gcgggcgtgg attcagaaga aattcagaaa gaattacaaa agagcgaggc
    36301 tatcgaggtg cagtatttga agactttcat caatcggata ataaactgtc tagaatactg
    36361 gcgaatagtg cttgggtgga aaatcatgtt tactatccag atgattgggc gacacgttgg
    36421 ccggactttt atgaggctat ggttagttat caacgtgaag gtaagaacgc tcatgatgat
    36481 gctccggatg cagttacagg aattgcagaa acgattatag aagcagatga cttcgagttt
    36541 attgcttatt aggaggtggg tctttgtttt attctggaat cacattgaaa aaatacaaac
    36601 gtttaagaac gaaatattca acgcaaatcg aagaaggatt attcgatcct aacgctttta
    36661 tggaagatat gaaacccttt ttcgatgatc gagaaagaaa gtatcttgct tatactagcg
    36721 agaaaaacga gatcgacagt cgtgagaaac caaaaacaaa aatcattaag gtcaataaca
    36781 agattcatgc gggaatgtat tcagtggtcg ttgatcaagc agttaaccat ttcacaggaa
    36841 taccaattaa atgggattat gatgtttcgg aacagaaaag gacattcatt caacgaatga
    36901 gagacaaatt actgggtaat gatatcagcg ccccttctac cccagaagaa tttgaaacac
    36961 tcacgagaca attaagtact atgcggtttg gaatgttaga ccccgatact gcaacatttc
    37021 aaggagcgac agggcttgct ttcagattac tggagcctgt tgagacaaat gatggttggg
    37081 aactaagagc aagcaacatt gagccgtgga aagctgaaaa gtacgaaaac ggcgcagtgt
    37141 acattaaaga gaaatacgat ccatatcaaa agaagtttta tgaagagatg aaggttgtca
    37201 cgccgaaatc aatatttact tatgctcgat atactgatta ccctggcacg gtacaaggag
    37261 catttaaaac gctgggtaat gttcctaatc ctttaggcgt tatcaatctt acggagttta
    37321 aaaacaatac aaaccgttac tgtgactttg aagttgcaga ggagattagt gatgctattg
    37381 atcgtgtttt atctgatcag cagaacgaga ttgaacaatt caagttagct tatatgctga
    37441 tcactggggc agatttgtcc gaggataaag ccaagaagat gatggagcaa ctagggatca
    37501 tcaatctgaa agaccctaat gcgaaagccg gctacgtgac aaaggatcta caaaaggatt
    37561 tcaacgagta tcattttgat cttcttaaaa agcaattcta cacggtgtgt aaagcaattg
    37621 atttcaatga cgaagtcttt aagtcgaata gttctgggga agcccgaaag tggcaaatca
    37681 ttagtttaga agctaagaca aataccaaag aacagtactt tcgagaagga ttgaaagagt
    37741 gtgccgaggt tatggctgct tatttggatt ttgccgagaa agttacaatt gatccggaaa
    37801 agatcatttt caccttctct cgttcgcttc caacagattt aagctaccta gctgaggcat
    37861 tgcctaagtt ggcaccatac gtttctaaga ggacgattca aagtcagatc ccgttcgtca
    37921 cagatgttga ttatgaaaac gaaatgattg acgtcgaaag cagacaatct tacccagacg
    37981 gcgagtatgg aggtggcatc gttgagtcaa atagaaacga agtactggac caaacgtcga
    38041 gaactggaag atttagcaag actcaaaatg gaaaatcaaa cgctaaagaa actaagtagt
    38101 gtctttcctg atgcgttgaa agaaattcaa gcggagttat tatcccaagc tgatttacac
    38161 gatattacct atgctgagat gatggaattt tatagtacaa gtgatcagaa aaaatatcgt
    38221 gaatacgttg aaaagaacta caaatcactg aagatgtatg atgcaaaata caaagagttc
    38281 atcgaagaat actttccttc tttcgactac gccaaagtga atcggctgct tcaaatgagg
    38341 tcagatattt ttcgaattct tgcagagagt gcaatagatg cagatgtgaa taaatatttt
    38401 tcggatcggt tagaagatat cttgcaacgt tcgtatgtat caaacgcaaa cgtatttgcc
    38461 cagattttga acgtagattt gccgaattac ttatcaaagg aagaacttga acgttacctg
    38521 aactatcctt ggtcaggtaa gacattctcg cgtcgtttat ggggcaatat ttcatctcta
    38581 gaacaaaagc tatctaacgc cattacaact agtgtagcaa gtggcgaagg agttctcgtg
    38641 gcattacgaa caatgcgaga agacccagaa atatgcgata tgttcaaaag ggaggaatcg
    38701 aagtacaaca aggcgatcga aaatcttgtg agaacagaat acgctaaatt cgctcaagat
    38761 ggtattgaga aatcttatat tgaaactggc gtagacgaat acaatgtctt aactgcaaaa
    38821 gatgaaaagg tatgttcaat atgcggtggc aaagcaaaga acaacccata caagttgagt
    38881 gaagcgatca ttggtgagaa ccgtgcgcct tttcatggcc gatgcagatg tacagatgtt
    38941 cctaatatgc cgaaattagg aaaagatatt gacgaagagt atgagcgttt atttggcgat
    39001 ttattagatg agtttgcaca tgattctttt ggaattaatt tgaaacggag gaagtagaat
    39061 gaaagatttt tttgaagcag tactaacaat taatgtaaat gctgatattg cagaagccta
    39121 caaaacagct attgagtctg agaaccatcc taatggcttg agagaccatt ggaatggcaa
    39181 ttatgcctac gtggttattg gcgatcaaac tgttaattat caagataata ctccagttga
    39241 taagaatacc gttaatttaa cgattcaatt attatctcat tcattaccaa atttaaaaga
    39301 aacagttgat tggtatgaaa atatgggatg tattgttgtt agaactgact acaaagaagg
    39361 aaagtctagt aattaggctt ttttattttg tccgaaatga cgttaaacta gcgcaatact
    39421 gggcttggtt gaatggtggg gcgcaactat taaaactcaa agcaatgcgg ggcgtgaaaa
    39481 cgaatcgtgg ggcgaaagga gaatgattat gaaacacaaa tcattaatgc caatgaattt
    39541 gcaatacttt gccgaaggtg acgatcaaaa gttttctttt gatgacttca aatcttttgt
    39601 ggaatccaat gaagaagctc aaaaatttat tcagtcacaa tctcaaagtg ttgccgacaa
    39661 acaattggaa gcttggaaac aaaataactt agataaaatt aaacaggata ccatcaagga
    39721 atatgaggaa tctaagaaaa acaagtcacc tgagcaaatt caactggaaa aactacaagc
    39781 tgaatttgaa gcagaaaaag cgttgcgtgt gacaagtgat aataaagcat ttgttgcaga
    39841 acaaattgct ggattagaac tagatggaga gttaaaagag tctatttctc aatttatgct
    39901 aaataatctt gttagttcgg atacagattt cactaagaat gctgttgaag gttttacaag
    39961 tgttttgaat gcaattaatg agaaacatgc agatgcatta aaagaactac aaatgaagtc
    40021 tgcatttggt ggaactcaac aatcgaataa ccaggttcag cagaacaatg aaacattaac
    40081 aaatccagaa gaacaattag gacaaattct tcaacaattt aactaggaga gtgaaaaatt
    40141 atgaaaaaaa catctttaaa taatttagag tatttggata tttcaccagc gattaatgct
    40201 atgcaagtac caaatacacc ttttttaagc tatttacttg gtgctggaaa aacagagcca
    40261 gcaaactcga cagaaattaa atggcgtgaa tatgatatca acaacgatga ttcttctgaa
    40321 aaacttgagg gcggagaata tccagatgct gaatcaggtc gaacttggtt taacaactat
    40381 actgaaattt ttagaaaatc aacctctgta tctggtacat tagatgctat taatgtgaat
    40441 ggagtcggaa atgaattaac taatcaagta gcactacgtg gtatggaaat gaaaattgat
    40501 ttgaaccgaa aattgattac tggtgtaaaa gctgatgaaa atggttctaa aggtcgtcga
    40561 atgaatggga ttttgaactt gatcaattca gcaaataagg cagaaacagc cactgcgggt
    40621 gcagtaacaa gaaaagatat cgatacttta tttaaattga tgtatgaaaa aggttatatg
    40681 ggagaaaaac tatgcttgat ttctccagat atgcaggagt taatgactga tgagttagat
    40741 ggaaaatcaa caaaaattgt tcagttcggg gaaagagtaa cttttggatt gcaaattgga
    40801 aatatcgtgt ctaattacgg tacaggtatt gctctactag aaccatcatt gccaaaagga
    40861 acaattgccg caatcgatac taattatgtg aaactacgtc cattacgtga atggagagca
    40921 gaagaacttg caaaaacaac ggattctaga cgtatcggtc ttgtaggtga atactctctt
    40981 gaatacaatg cttcaaactc tggggcaatt ttaaatttaa agtctgaata aaagggagtt
    41041 agtactccct tttttgatag gaggaattac agtggtaaaa aaagatgaaa ctaaaaaaga
    41101 tgaagtcgtg aaatatagag taggtaaaac taaaaatttt gttgggtttg ttcatcctaa
    41161 aactcgtaga tttatcacag cagattcaaa taacgaattt atcatttcta tagatgataa
    41221 agaagcaatt gcaattttgg aagatgcaat tgatgttaat gaaatttagg aagtgatctg
    41281 atggatgaat cgctaaaaac ggaaatcatt gagtctacaa aagaagattt tccagatttg
    41341 agtgaagaac gcataactaa tttattagaa ataattttgc tagaaattga atcatacaac
    41401 acttgtaaaa atgatatttc atgggaaaag ttaaaaagcg tgattagtga agtgttgtat
    41461 aaaataataa aaaatgaatc agaaaaaaca gtatcttcag ttagacgtgg cgatacaacg
    41521 attagttatg cttcaacaac aaatgatgtt agtgagttac ttctaggcta tggtgatttg
    41581 atacgaagag ttattggttg tggaggattg gagttttttt aatgaatgaa gcagatattt
    41641 tagaaactac ttatgaagat agttgtatta ttgaaagact gacggacatt gaagattcta
    41701 atacaaatat tactattcaa gattacaaaa aagtatatga taatcctatt tcttgcgctc
    41761 tttcacaagg tcaaatcgat ggactagcag tcatagaaga tggagagatg gtaaatgttt
    41821 caactgacac atataaatta tttgttcatc ctaagattaa actaaaaaaa ggagatcgaa
    41881 taacaataac tcaaaaggcc agtggcttaa ttttttctct atttgctact aagccttttt
    41941 actatcctag tcattgtgaa gtgaatttga taggaagtga gaaaaatggg taatctcaaa
    42001 tatgaatcaa atgcagaaaa gatcattgag aattttaaaa atatgactgt aattgctcaa
    42061 aaagaaggaa tatccttcgt taacgattca atgaataaag tcgttagttt agctaaacca
    42121 ttaactcctg taaaatcagg taatttaagg cgaggatatc gtgtagtaaa agctagaaaa
    42181 ctatcaagcg gtcgaattgt tggagcagtt ataaacaatg aacattattt taaatatgta
    42241 gaagaaggtc ataggactaa aaatggtggc tttgtcaaag ggaaattcat gttaactcgt
    42301 gcaacgaatc ttgcaaatat gtcttatatt cctcgaagat ttaaacaaat ggcaataaaa
    42361 atcgttaaga aaggaaagta acatgaaaga tgaaatcatt gctgcaatca gtagcaaatt
    42421 aaaagaaatc tatcctgatg ggacaatata tcttgattca gttatgcagt caactaaaga
    42481 tttttatttc gttttatcag taatggaatc tggaactgaa aatgtaggaa ttgatattca
    42541 aaatgtttct ttcttaattg atattgcatt gattgataat aaacctaata gaaatttaat
    42601 taatgaatta gtctcacgtt gtgggacttt ttttaatacg attacaatcg atgagcaaat
    42661 attatttcca aaagcctatt tacctgatga agcagatggt gttcaacata ttcgttttac
    42721 attagaattt ccacaatata ttgaatggag tgaaagataa atgggagaaa aaagaagtaa
    42781 aaccggaatt atttctgtcg aaaaacctac ttggtttcct ttggaagatg agacagggaa
    42841 tttcccggta tatggtactg cgttgccaat gggaacagca gtaagtatca aaccaacagc
    42901 taattatgaa acaacacaag attatgggga ttcagtggtt caagatcaat ttacagcttt
    42961 tggtggtgca gaagttgaac tggaagcaaa tggatatact cataaagttt tatctacaat
    43021 tactggaggg aaaattgtta aaggtggtgc cttgcgttct ggagaagata ttgcgcaaga
    43081 tggtgcgttt gcatatagac gtaaaaaatc gaatgggaaa taccgttata cggtctttta
    43141 taaaggacag tttgctctag attcagatga aacgtcaacg attgaaggaa gtaaagtaag
    43201 ttttactcat ccaacttgga agggttcatt tgtagatgta ccaggacttg gatatatgta
    43261 ttcagttgat gaagatgatg aaggcgtgga taaagcaatg atcggaaatt ggtttacaaa
    43321 agtagcaatt ccaattgaag aagcagaact ttcaggaggt acagaataat gtcaaaatat
    43381 caaacaacga ttaaattaac gaaaaaagat gaagaaggta aatatgagca agtacaattt
    43441 aaatctgctg aatttttacc aggaacagtt gtagaagatg ctgcaggagt tatggaagaa
    43501 atgcaaacag cgactgataa acaatcagtt aaaaaagctt taagtcgtgc ttattcattt
    43561 attgcagata ctttatttga gggacaattt actggtgaag attattgcaa aggaattgat
    43621 gctcgtgaga ttgcctcatt gacaggaaaa ttattgaagt ctgttactgc aggttttgat
    43681 gaaacttata cagagacgaa aaaaaagtaa gtgaggcgct caagtcacct tcatttaagt
    43741 attcgattac ttaccgagaa ttagatataa agacgcaatt actcgaagca ggttggacgt
    43801 taccagaaat tgaacgtact gacttggatg agttaatgcg tctttttgct tttagagatg
    43861 cggtaaaaga gcatgaagat gttgagtact atgataattt cactcaattt taggaggtga
    43921 tactttgaat aacgatgacc taattctgaa gatgatacta gatgaatctg gttttactgc
    43981 cggtatgaat aatgctgtca aaaagttgaa ctcttttgat gaaacaatcg aaagaaaaag
    44041 tagaaatagt ggcagttcat taggtagtat ttggaaaata tttgctggaa gttttctagc
    44101 tagcggagta actagaatcg taggagctgg ctttgatcta atcaagggtt ccataagtgg
    44161 agcggttgat cgagtagata cgatgaataa cgctctacga aatttccaaa atatgggatt
    44221 tagtaattca gaaattatga agaatatcgg aaagaatggg cttttatctc aaggtattca
    44281 aggacttcct actgctttga atgatgcgat aagtcatgtt caacttcttg cttcttctac
    44341 aggtgattta actcgttcaa ctcaaatatt taaagcttta aatgatggaa ttcttggttt
    44401 cggtggttca actgatcaag ttaatgaagc tgttattcaa ttatctcaaa gtttctcaaa
    44461 cggaaaagta gacgcacaaa cttggaactc aatgatcaac gctcaacttg gacctactct
    44521 ttctgctatt gctaaaaaga tgggaattac aatgggagat ctgaaagaag gtttgtctca
    44581 aggtaagatt tctgttgaag aattccaaaa tcaattaata gaaatggata ccaaaggtgg
    44641 cggaggactt aaatcattaa gtcaaatcgc taaagattct actaagggaa ttaaaacctc
    44701 tatacaaaat gcaaaaacag ctgttacacg tggtgttggt gaggtaatag aaggattaaa
    44761 taaagcatta gtagattcag atttaggtgg atttaaggga attattgata aagtgggcag
    44821 ttcaatggaa tcgttcttaa aagtaattgc tgcaaatatt cctacagcag tatcattttt
    44881 aagtaattta tttaacgaaa ttcaaaaatt tggttctgct ttgaaattca tgatgccctt
    44941 tcttgttcct gcagctaccg cttttggagc gttcatgttt caacttaaag gtataccagc
    45001 aataataaaa agcttcaata attttaagaa tgccataatt ggcgttggaa attcattaaa
    45061 gattatgggg gcaatagctg ctgctaattc atttgtttta attattggtg cagtcgttgg
    45121 tgcaatagct gttttcggtt actttatggc aaccaatgaa gagtttagaa acaaggttat
    45181 atctatttgg aatgatgtga aagattccgt aattggtgta ttaaaaaata taaaggactg
    45241 gggaattgat acttggaatt ctgctaaaga aatggcatca aatgcagttg agggtgtcaa
    45301 agatgcttgg tcaggaacaa aggaatggtt ttctaacacc tggaaaggta ttaaggatgg
    45361 ggccacaggt ttatttgata aaacagtaga gacttcaaga aatgcagtcg atagtgtaaa
    45421 aaatgcatgg tctaatatga agaaatggtt ttctgatact tggcaaagta taaaagattc
    45481 agccagagaa aaatggaatg aaattaaagg ttctattatg tcggttgctg gtccattgat
    45541 tacaggtata aagaatgcat ttttacatgt tactttttat ctagagacct tatggaataa
    45601 tttagttgag attggtaaaa acgtctttga gattttaaaa aatgttatac ttgcgccggt
    45661 tttgtttatt acctccatga tttctggtgg atgggaagaa acaaaaaata atatgattgc
    45721 tgtttggaat aatattaaag aaagtgccat aaatatttgg gaatctataa agaatatatt
    45781 tgtaagttat tttacaaata tttattttgc tgcactcaat atttggacag ggttcaagct
    45841 tacattgata aatatttgga atgaagtggt aaatcaagct aaatcgattt ggttaaacat
    45901 aaagtatttt tttattaatc tttggattga tataaaatat tttgcaattc agaaatggat
    45961 tgaattgaag ttttctatta ttcaaacttg gatcgattta aaatataatg ccattactac
    46021 ttggaataat attaaacagt ttttcaaaga tacttggaaa aatattaaag atacggcata
    46081 caatacgtgg atttctataa aaaataccat gattaataca tggaataaca ttaaggactc
    46141 tttctggaat attgttactg gaattgttaa ttctgctgaa aatgcatgga caaatctaaa
    46201 aaatggtgtt tcaaatgcta ttaatcgggt aaaagaaatc tttaattcgt taagggaagt
    46261 caatttattt gaaattggca agaacatcat tgatggactt ataaatggtg taaaagaaaa
    46321 gtggaatgct ttgaaagata ctatcaaagg tattgcaggt aatatcaaaa attggattaa
    46381 aggagcttta gatattcatt ctccatcaag atggatgcgt gatatggttg gtaaaaatat
    46441 tgttcaaggt attatcgttg gtattgataa agagcaaagt aagttagatc aaaccatgac
    46501 aaatttagta aaaacaccgt ctgttcaacc tgtagtaaat ggaataagtc acctaccaat
    46561 tacacaaaca aagcaaaata tatctgctag tgaaacaaaa gaaattcatt tacatttaaa
    46621 tgtttatgga gatttacctg attcaatggt tcggaagatt accacaaaaa ttaaaacaga
    46681 attgacaaga caaatgaaac gagatgctgg tgcagtagga ggaacattat atgcaactta
    46741 agagaggaca attttttatt aatcaacatt attcttctga atttaatgtg tatattcaaa
    46801 acaggcctgc ttctgtttca gctagtcgag taattgaatt gagagagcga gaaggaaatg
    46861 attctatcat tattgataaa ggctattaca gaaatgtgac tagaaagatt gagtgttact
    46921 ataaagcacc ttcaattgat gtggtgcagg agtgggaaga tcgaatcact gaatggttag
    46981 atatgtcgtc ttatagtgat tttattcttt actatgatga acaatatatt tatcaagctg
    47041 tagtaataga aggacctgaa tttaaaggaa caagaaaaac aggaaatatt gtcccttttg
    47101 aatttacagt gagcattcga ccatttaagg aaaattacaa tggtagattt actattcgac
    47161 aaacagaaac ttttgaaatt tataacccag agaagtattc ttcaaaaccg cttattaaat
    47221 tgagtggttc tggagatgct tctttttata ttaataagga caaatatgat ttgaaatcgt
    47281 tggacagaga attatttata gattctaaat tagaagaggc ttaccgaaaa ttagatggta
    47341 atttagaaca tcaggatcaa gtcactttat ttttagattt tccattttta tatcctggaa
    47401 aaaatgaaat taaatggacg aaaaatattc attcatttga aataatgcct aggtggtgga
    47461 gaaaagtatg aaaccaagaa tatatagtcc tactgaaaca gatttctcaa cgaatggctt
    47521 aggaatttta aaggattgta caagatgtga aatatatgaa gtagctaatg gaaaatatga
    47581 attagagttg gattatcctt taggaactag atttgatgaa tattttgaaa atgactatca
    47641 aataaaagca aagccaaacg atcaagaaga gtatcatatc ttttttattg atgataaaga
    47701 tatagatact tttttaaata cagtaactat ttatgctcag agtcgtacaa atcgacttgg
    47761 aagacgggta gtcactcttg cggaagtaga ctctaaaact ggtcaagaag cgatatcaat
    47821 tattgaaacc aaaatggata aaaaatctga catacgactt tattctgata ttacggccgt
    47881 ttctagcaca atctttgaag cgagaaatgt tttaaattgt attgctggtg aacaaggatc
    47941 attgcttcaa tattggggtg gagaaattaa acgtgaacca tttaagcttt ctttgttaaa
    48001 gcgaagaggt cgcaataatg ttggaacgat tcggtatgga aaagatatgt ctggtttaaa
    48061 ggtcaaatta gattggacag gtataaaaac aagacttatt ccatatgctg atcctcaaag
    48121 tgaggtaggt acgactaatc gaatttatgg ttcgccagta gatagtgcct atattaataa
    48181 ctatcctgat gtgtatacag agcatgttca gtttacagaa gaacaaggag taaaagacat
    48241 taagagctta aataaaatag ctaaaaatta ctttaaaacg atcaatcctg gctgtgataa
    48301 gcctaaagtt tctattacgg ttgaatttga taagttgact gatagtgaag aagcgaaaga
    48361 atttgcgaag attagaaatt atggtctgtt tgatacattt aaaatatatc ataaaaaata
    48421 taatatttat cttgaatcaa aggttagtgg actacaatac gattctttat ctgaaaaaac
    48481 tttgaaatta gaagcaggag acattcaagt tgctttttat cagcaacaag ctgtaactat
    48541 tcaggataaa ttaaaagatt atgcaacgaa taattatatg agtgatttta atgattatgt
    48601 ttcttcaatg attacaggtc aaggcagtgc aggaggatat gtaagtttat ggccaaaaga
    48661 aaaaccttcc aacatcttta ttatggataa tccagattta gaaaaggcaa gagaagtact
    48721 aagaatgaat aaaaatggga ttgctttttc taagaaagga tggcgggggc cttttacttc
    48781 agcttggaca ttagatagta tatttaatgc caattttata caaactggat taatcaaagc
    48841 agatatcttt caaaattctt ttaacaagac tggagatgta ttgaaattag ttaatggact
    48901 actccaaatt tggaacaaca aaaagaaaat aatggagtta actaaaaaag gaatggaatt
    48961 ttggaattct aagggttcaa ttggaacgat tggaacaact gattctgctg gtaatccttt
    49021 tcctggggct tctactccaa cccctattga agataattct ttagttattc gtacaaatgg
    49081 agacggcaaa tatattttga tttctcctaa agtaggaaaa ggattagttt tattaggaaa
    49141 tggtaaagca atttattttg gagacttaga tgtacaagga aaacttacag ttaaaggaaa
    49201 agaaataatt cctggacaag gtggtggtcc atcgggaggt ggagaatcta ctggtgggta
    49261 tcctagtgaa ttaaaaacag atgcagaaaa gagagcttgg agaat
//
LOCUS       DAPBAF010000021        45828 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.021, whole genome shotgun sequence.
ACCESSION   DAPBAF010000021 DAPBAF010000000
VERSION     DAPBAF010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 45828)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45828)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45828
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.021"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(78..1088)
                     /locus_tag="RD451_001352"
     CDS             complement(78..1088)
                     /locus_tag="RD451_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDT7566621.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(1268..1612)
                     /locus_tag="RD451_001353"
     CDS             complement(1268..1612)
                     /locus_tag="RD451_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HDT7566622.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(1605..2039)
                     /locus_tag="RD451_001354"
     CDS             complement(1605..2039)
                     /locus_tag="RD451_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HDT7566623.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            2177..2914
                     /locus_tag="RD451_001355"
     CDS             2177..2914
                     /locus_tag="RD451_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7566624.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            2907..4118
                     /locus_tag="RD451_001356"
     CDS             2907..4118
                     /locus_tag="RD451_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7566625.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            4322..5104
                     /locus_tag="RD451_001357"
     CDS             4322..5104
                     /locus_tag="RD451_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HDT7566626.1"
                     /translation="MMEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAA
                     LSREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLK
                     TMLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHG
                     DVNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDE
                     MLEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            5174..5836
                     /gene="trmB"
                     /locus_tag="RD451_001358"
     CDS             5174..5836
                     /gene="trmB"
                     /locus_tag="RD451_001358"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HDT7566627.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(5934..7688)
                     /gene="ade"
                     /locus_tag="RD451_001359"
     CDS             complement(5934..7688)
                     /gene="ade"
                     /locus_tag="RD451_001359"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HDT7566628.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNKQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            7820..8749
                     /gene="tadA"
                     /locus_tag="RD451_001360"
     CDS             7820..8749
                     /gene="tadA"
                     /locus_tag="RD451_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HDT7566629.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLKLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            8706..9755
                     /locus_tag="RD451_001361"
     CDS             8706..9755
                     /locus_tag="RD451_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGB"
                     /protein_id="HDT7566630.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            9752..10030
                     /locus_tag="RD451_001362"
     CDS             9752..10030
                     /locus_tag="RD451_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HDT7566631.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            10005..10475
                     /locus_tag="RD451_001363"
     CDS             10005..10475
                     /locus_tag="RD451_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HDT7566632.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            10492..10794
                     /locus_tag="RD451_001364"
     CDS             10492..10794
                     /locus_tag="RD451_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566633.1"
                     /translation="MESLTALMIASVCVYLVSFGQLFLLQAEKKSGEELLFIRMIYED
                     IKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAISIEKTSNSSIYAD"
     gene            10811..11182
                     /locus_tag="RD451_001365"
     CDS             10811..11182
                     /locus_tag="RD451_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComGF family competence protein"
                     /protein_id="HDT7566634.1"
                     /translation="MILSSLLLTFNLLIQQTIQVSEFLQRKDQKEWLIFLAQLEEELK
                     SSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQPMLTSITELQLLEKEHTI
                     SFYVHFENGEDGYAIWTKNDQ"
     gene            11154..11513
                     /locus_tag="RD451_001366"
     CDS             11154..11513
                     /locus_tag="RD451_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566635.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            11685..12692
                     /locus_tag="RD451_001367"
     CDS             11685..12692
                     /locus_tag="RD451_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDT7566636.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            12717..13901
                     /locus_tag="RD451_001368"
     CDS             12717..13901
                     /locus_tag="RD451_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HDT7566637.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(14338..15921)
                     /locus_tag="RD451_001369"
     CDS             complement(14338..15921)
                     /locus_tag="RD451_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HDT7566638.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIALVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(16499..16642)
                     /locus_tag="RD451_001370"
     CDS             complement(16499..16642)
                     /locus_tag="RD451_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HDT7566639.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(16864..17343)
                     /locus_tag="RD451_001371"
     CDS             complement(16864..17343)
                     /locus_tag="RD451_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HDT7566640.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(17416..17700)
                     /locus_tag="RD451_001372"
     CDS             complement(17416..17700)
                     /locus_tag="RD451_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566641.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(17778..17972)
                     /gene="ssrS"
                     /locus_tag="RD451_001373"
     ncRNA           complement(17778..17972)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="RD451_001373"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(18044..19330)
                     /locus_tag="RD451_001374"
     CDS             complement(18044..19330)
                     /locus_tag="RD451_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HDT7566642.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            19468..20139
                     /locus_tag="RD451_001375"
     CDS             19468..20139
                     /locus_tag="RD451_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HDT7566643.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            20105..20593
                     /locus_tag="RD451_001376"
     CDS             20105..20593
                     /locus_tag="RD451_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HDT7566644.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            20606..21553
                     /gene="prmA"
                     /locus_tag="RD451_001377"
     CDS             20606..21553
                     /gene="prmA"
                     /locus_tag="RD451_001377"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HDT7566645.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            21554..22318
                     /locus_tag="RD451_001378"
     CDS             21554..22318
                     /locus_tag="RD451_001378"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HDT7566646.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            22551..24764
                     /locus_tag="RD451_001379"
     CDS             22551..24764
                     /locus_tag="RD451_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HDT7566647.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            24775..25221
                     /locus_tag="RD451_001380"
     CDS             24775..25221
                     /locus_tag="RD451_001380"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HDT7566648.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            25392..26651
                     /locus_tag="RD451_001381"
     CDS             25392..26651
                     /locus_tag="RD451_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HDT7566649.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(26740..27687)
                     /locus_tag="RD451_001382"
     CDS             complement(26740..27687)
                     /locus_tag="RD451_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HDT7566650.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            28081..29373
                     /locus_tag="RD451_001383"
     CDS             28081..29373
                     /locus_tag="RD451_001383"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HDT7566651.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            29388..31157
                     /gene="aspS"
                     /locus_tag="RD451_001384"
     CDS             29388..31157
                     /gene="aspS"
                     /locus_tag="RD451_001384"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HDT7566652.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            31266..32141
                     /locus_tag="RD451_001385"
     CDS             31266..32141
                     /locus_tag="RD451_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDT7566653.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            32407..34290
                     /locus_tag="RD451_001386"
     CDS             32407..34290
                     /locus_tag="RD451_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HDT7566654.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(34365..34649)
                     /locus_tag="RD451_001387"
     CDS             complement(34365..34649)
                     /locus_tag="RD451_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HDT7566655.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(34639..35373)
                     /locus_tag="RD451_001388"
     CDS             complement(34639..35373)
                     /locus_tag="RD451_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HDT7566656.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            35502..36125
                     /locus_tag="RD451_001389"
     CDS             35502..36125
                     /locus_tag="RD451_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HDT7566657.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            36317..37438
                     /locus_tag="RD451_001390"
     CDS             36317..37438
                     /locus_tag="RD451_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HDT7566658.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            37445..40573
                     /locus_tag="RD451_001391"
     CDS             37445..40573
                     /locus_tag="RD451_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HDT7566659.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            40592..43786
                     /locus_tag="RD451_001392"
     CDS             40592..43786
                     /locus_tag="RD451_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HDT7566660.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(43932..44639)
                     /locus_tag="RD451_001393"
     CDS             complement(43932..44639)
                     /locus_tag="RD451_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HDT7566661.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
     gene            45404..45802
                     /gene="spxA"
                     /locus_tag="RD451_001394"
     CDS             45404..45802
                     /gene="spxA"
                     /locus_tag="RD451_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HDT7566662.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
BASE COUNT        14760 a         8092 c         9564 g        13412 t
ORIGIN      
        1 gatttatagc aaaaatttat ttttttcatt caaaacaaaa aaagcgagac ataagtcttc
       61 gctttttttg ttttctttta ttttgatgaa tcagttgttt cttcagttga agattctttt
      121 gttgaatcag ttgattttgt gtcagaactc tttgttgaag ctgtagtttc acttgagtct
      181 ttcgtacttg atgaagttgt tgtgaatgca ctcaacacat tttcaaaggc atcatctttg
      241 atttttacat ttgcatcttt taattcttca ccgattactt tagttgtgaa tgcattgtca
      301 cttagtttag tttcagtagc gatatctttt agttgatctt tgtatttatc catgtcattg
      361 cctttatttt ggtttttcac cattttgaca acgtagtatt ctgtcgcata agaagtagga
      421 tttgttgtag taataacatc ggagatctca ccgtctttca atttgaaagc tgcttctttt
      481 acttctgcag gaatagttgt tgtcgttgag tcgaatttaa ctttaccgcc atcttctttt
      541 gtctctgtat cagttgattt gtctttggct aatttagaga aatcatctcc atcatccgct
      601 gattttttca catcttttgc ttcatcttca cttgataatt tgatgatttg tgcttctact
      661 tctggatgga aagatttcca agcagttttc aaatcgtcat ctgtaatatc tacgtgagct
      721 ttcaagccag cttcaaaagc taaattgtta cgaatatatt ctttataagt atctttcgta
      781 tatccagcag cttctaattg tgattcaaaa gtatcaccta atgatttcgc ttgtttgtcg
      841 tattctgcat ccacttgctt atcggttact ttatcgccat atttgttatt gaatacttta
      901 taaatgatca tccgttgtac taaggattgg ttcgatgatt caagttttgc ttcatcatag
      961 aaatcagata cagtgatcgt tccgcctttc atcgttgcga tatctttatt agtatcgcct
     1021 gaacaagctg ctagagttaa aacagccaac gcactagtag ctgccaaaat aattgatttt
     1081 tttttcatta aaatttgcac tcctgtaatt agttattatt tttatatatt aactatacca
     1141 tatcccattt cctttaaaaa cgttgtcgtg gtagtttcaa acaaaattca aaatttcatc
     1201 acattcctag gaaatacgca aacttttctc acttatatag ttaaatctgt tgagaaaata
     1261 atcattatta tatttgttca ggatactctg gcagatcagc ttttagtttt tctacttgtt
     1321 cattgatttg tgtgatacgt ggttcggctt ggaatttaaa atcttcgata tcttttttga
     1381 ttgcttcttg gaaagcagga atcacagatt cagctgtttc ttttgtttcg atcaatgcgc
     1441 ttttaaaatg attcaggctg ttatttaaat catttgtcag agttgttgct tcttccaatt
     1501 cttcgatcag tttctttctt gtttcattcc cgctcctggg cgccaataac agacctccga
     1561 cagtgccagc agcagctcca aataacagtc ctttgaaaaa gtttttaatc atcgcaggac
     1621 acctgcttta cgattgtttc ttgaatagct tttagttctt ccgatccata actatcttga
     1681 tgattgacaa agtgaataga aaaatcatcc tctttgctgt agcgagggac taaatggata
     1741 tgtgaatgaa aaacagattg ataggctagt tcacggttgt tattcaagat attaagacct
     1801 ttcatttctg gaaaagcttt ttccaatgct tgagcaatct taggcacacg cgaaaaaacc
     1861 tctcctgcaa gttcgggatc atattcaaaa atatctgcta catgacgttt aggcacaact
     1921 aatgtgtgtc ctttcgttgc ttgagagatg tctaaaaaag catagacctt gtcgtcttca
     1981 tatattttat agcttgggat ttcttgattg atgattttgc aaaaaataca gttttccata
     2041 taaaacatcc tttctataaa gaataaatac ttcagcttaa ctttaccata agttaaagct
     2101 attgtaagga aaaaaacaaa ataccgtcat tttcttcgtg gtataataaa taaaaataaa
     2161 tggcggagga aaaagaatga gtttaattat cgatcatgtc acaggggggt acggacatct
     2221 ccctgtgtta aaagatatca gtttcgatgt acagcctgga gagatagtag ggttgattgg
     2281 actgaacgga gcagggaaaa gtacgaccat caagcacatt atcggtctgc tggaagcttc
     2341 aaaaggaacg atagaaatca atcatctatc cttaaagaaa aatacggaag aatatcgcaa
     2401 acaaattggg tatattccag agactccttc tttatatgaa gaattgacat tgagagaaca
     2461 tatcgaagtc actgcgatgg cctacgatat acctatggat atagcaatga aaagagcaga
     2521 aaagttgttg gagacttttc ggttatctaa tcgtcttgac tggttcccag ctaatttttc
     2581 aaagggaatg aaacagaaag tgatgatctt atgcgccttt ttgatcgagc cttctttata
     2641 tatcatcgac gaaccatttt taggcttgga tccactagct atcaatgcat tgcttgaatt
     2701 gatggtagaa atgaaaaaag aaggagccgg tattttgatg tctacgcata ttttagctac
     2761 tgcagaaaaa tattgtgatc gttttgtggt cttacataac ggagagatac gagcagacgg
     2821 ttctcttgag atgttgagaa aagaatttca gctgccggat tcttctttgg acgaaatcta
     2881 tattgcttta acaaaggagc aggcacatga gtagtttttt tcaaaaacgt ttagcaagac
     2941 atcaaaagaa aatgatgaaa tatatgcgtt atgtattgaa cgatcatttt gttttagttt
     3001 gtcttttctt gattggcggt gtgggattat attattctaa ttggttgaaa accctgcagc
     3061 caccgtttgc aattggaggg ctcataatct ctgtattttg gatgctctgt ttattcgtgg
     3121 gtaagatggc tacttttgca gaggcagcag atattgtttt tttacttcct aaagaaaaag
     3181 aaatgcaaac ctatttggaa cgagcttttc gctattcttg catttttccg ttgatctttt
     3241 tgatattggc atgcggattg gccatgccat tagtggtggt tagtacggag caatcctttt
     3301 cgatgttttt cgtctatctg atcatattat ggagtttgaa attcagtcat ctgcaaatca
     3361 agagagcaga attgtttcga ctagatcaac aagttattcg ttattggaaa ttaggctggt
     3421 ttttttcttc tctgatcttt ttgtttctat cattttattg gctaatatgg gcaggaatag
     3481 caggtgcatt agtacaggca agtctatatt actggttttt gtggaagcaa caagaaaaag
     3541 gattggattg ggagaaaatg gtgcatgtag aagaacatag gttgcatcag atctatcaat
     3601 ttatcaattt attcacagat gttcctgaaa ttacggcaaa gatcaaaaga agacgctatt
     3661 tggatcctat attgactcat attaaaagag aatcaaaaaa cacttatctt tacttgtttg
     3721 caagaagatt agcaagaggt tctgatttta gtggtcttta tttccgatta gtaattatag
     3781 gtgggttatt gattgccgga gtagtcgact tttattttag tctgattatc ggtttcttat
     3841 ttttatattt gatcggtttc caactgttac ctttagcgaa ccagttccgc tatatggttc
     3901 tcgttcagct ttatccaatc cataagaatc agaagaagca ggcgattcag tatctactca
     3961 catgggtatt aattatcgcg tcggttattt ttggtttgat tgctgcagtc gtattagatg
     4021 ggcagcagcg atgggttccg ctagcggctt atttgattgt tactatgctc tttgttaaac
     4081 tatatgtacc aactcgtttg aagaagatgt cagactgaaa acaaagctgt gtagggtaaa
     4141 aatgagaatg aaaaatagag cgttgacagt aagaatgctg ttcgttctat tttttttgag
     4201 aaaagctggt tttttgaatg gcaattaaat gaaaaagaac gtatatgtgc ttgacgtgta
     4261 gtgttcaggc gactagaata ataagtactg caaaacaaag agtaagagga cgggagaatg
     4321 catgatggag tttcagttag accaagagtg gcggttacgt cccatcaaag gcgacacagg
     4381 aaaaacatac ataggcatgc gtgatgagga caaagtcttt attaaacgaa acacgactcc
     4441 gatgttggct gctctttcaa gggaaggaat tacaccaaaa cttgtttgga caaaacgaac
     4501 ggggaatggc gatactttga cagcacaaga gtggctggaa ggtcgcttgc tgactcctaa
     4561 tgagattggt caaagaaacg acgtgattga tgttttgtac catttacatc attcaaattc
     4621 tcttaaaacc atgctgaccc gtatcggtgg tcgtgtcatg acgccggaga agatgctgca
     4681 aaaatatgaa aaagaattac cggaagaact ccagaaaaat caatttctgc aaattgtcca
     4741 tcgttttctt cgtgagcaga tcccgtcaat agataaggaa aacttatcag tagtacacgg
     4801 agatgtaaac catcgtaatt ggttagtatg taaaaattat ttatatctag tcgattggga
     4861 ttcaatcatg tttgcagacc ctgcggtgga tattgcaacg attttaggaa attatgtgcc
     4921 actgtctagc tggaatcagt ggctgatcag ttatggcata cgcccgactg acgaaatgct
     4981 tgaaaaattt cattggtatg cggccatgaa tttgctccaa gaaatcacca gatattgcaa
     5041 acgtgaagat catcgacgga tgaacgaaga aattttacaa ttaaaacgaa ttttcagtgg
     5101 ctgaggtttg gcccaaactc tgcggagatt tggccagacc tttttaatta gaggaaagga
     5161 atggagataa ataatgcgtg tccgaaatcg tccgggagca gcggaaatgt tagcggctca
     5221 cccgaatttt gtaattagtg atccaacatt gtggaaggga aaatggaatg aattgtttga
     5281 aaacgatcat ccaatccaca ttgagattgg tatggggaaa ggccagttca tcactggaat
     5341 ggcaaaagcc catcctgaaa tcaattatat tggagtagaa atgcaggtca gtgttgtttc
     5401 gattgcacta gacaagttga tcgaacaacc gcttcctaac ctgaaacttc tacatgtgga
     5461 tggatcagcg ttgacagagt atttcgctga cagcgaagta gatcaaatct atctgaattt
     5521 ttccgatcca tggccaaaaa aacgtcatga aaaacggcga ttgacatata agacttttct
     5581 tgctgtagat gaacagattc ttcgtccaaa tggagaaatc catttcaaaa cagataatca
     5641 aggattgttt gagtattctc tggcaagttt ttctcaatat ggcatgatcc tcaaacaggt
     5701 atggttagat ttacatcaaa gtcaatttga aggcaatatt atgacggagt atgaagaaaa
     5761 attttcttca aaaggtcaac gtatttatcg agtagaagct caatttcaag ataagaccaa
     5821 aaagaaaagt ctgtgaaact aactttctgc tttcataaaa acattaatat ccataaataa
     5881 atctcagaaa atgaacatta cagatgtaat gtattttctg ggatttattt gatttaaaat
     5941 gtatttattt catcggtttt tccacaaggt ggaatcaatt ggaagcgaga aaatgaaaat
     6001 aatcctttgt cggtgatctt caattcgggt atgacagata atgttaagaa agaaagtgtc
     6061 aaaaaaggat caaaggtttt agctgctcct agttgatgtg ctttagttat taattcattc
     6121 aactgttcat agacgatcga aaaaggttcc tgtgtcatga ttccgcctat aggaagagaa
     6181 acacaagcta tttcctgctg tttgttgaca acggtcatcc cgccaccttt ttgaatcaaa
     6241 agattagcag catacagcat atcctcgtcg tttgtcccaa cgacaactag attatgcgag
     6301 tcatgggcaa tcgttgtcgc tatcgctcct tgtttcagct gaaatccttt cactatgcct
     6361 aatccaatgt ttcccgtttg atggtgacgc tcgatcaccg caatctttaa ttggtctttt
     6421 tcgattgaag gaatgaatcg ttcgccttgt cggtccactt tttctaccaa atctttagtc
     6481 actagactat tcgggataat ttcgatcaca tgggcttgtg aagaagaaag aagcagctct
     6541 aacgaatgtg gatttaatgg ttgagcgttt agttttggca gacaacacgt atatgaattt
     6601 gaatgatcag caaataaatg gtcttggagt tgcccagatt gaacaactaa tgttccctta
     6661 tagaaaactt catgaattgg cagcttggta agatcgtctg ttaagaagaa atcagcttga
     6721 tacccagggg caatcgcacc tagtgttttc aaatcaaaac attctgctgc attcaatgtt
     6781 gccatctgaa tggcttgtaa tggatcgatt ccaagtgcaa tagcttgacg gacgatatga
     6841 tcgattgatc cttcttttac taaatcattg atcagtttat catcggtgac aaagaagcat
     6901 cttcttgaat tttcaggtgt gatcgccggt agtagcgatg ccagatcttt tgcaacggtc
     6961 ccttctcgaa ccattaaata cataccaaga tccaaacgtt ctttagcttc ttttgcagtt
     7021 gtagcttcat gatccgtccg aatacctgct gcaggataaa catttaactc ttccatgccg
     7081 ataccagctg catgcccgtc aatttttttc ttatgctggt gcatcaattg gatcttttct
     7141 aggatgtctg tttcattatt tgctactgct tgatagttca tgacttcagc taagcctaaa
     7201 acttcgggtt tttgtaaaaa aggggctaat ttttttgcat ttaaatttgc accattggtc
     7261 tcaaaagggg ttacaggtac acaagaaggt agcataaaaa agatattcat gagtgtttgt
     7321 cttgcatctt ctatcataaa ctcaagacct gtactcccag caatgtttcc tatttcatgg
     7381 ggatctgtca ctacagtagt aactccatga agcaaggata cttttgaaaa ttcgcttggt
     7441 gataaaagtg agctttcgat atgcacatgg ccatcgatga atcctggcac tagatattgc
     7501 ccattagcat tatgtacgct ttttccttcg tattcaccga ttcctacgat cattccttcg
     7561 cagattgcta catctttttc catgatttct ttcgtaaaga cgttgacgat cttagcatgc
     7621 ttgatcacta ggtcagcagg ctttttttta cttgctactt cgatatattt ccttaatgtt
     7681 gtttccaatg gagtgcctcc caagataaat ttttataagt ataacataaa ttcggctttt
     7741 gccaatattt ttttgtaaat tcattttatt tgaaacaaaa agatcaaaaa gacgtatgtt
     7801 ttttgtggag gggagaataa tggaaataaa acgattatcg gatcaaatga taagtgaaag
     7861 ttttgccaaa catgcccaag acgtatatat attgccagct tcagaagtat tttacatcta
     7921 ttttcgctat ggaaaaaaac gaacattctg gaagaaagtc tcttcggcag atggacagca
     7981 actgatctca agatttaagt atttgggaca gatggatatc ggagaaaaaa gaaaagctca
     8041 gttaggtgca tttacttatt ctttagaaaa acaggaagtt cgtctgcggt tgtcttctgt
     8101 aggagattac cttcaacgag agagtttagt gattcggcta ttatacggta cttttgaaac
     8161 accccatcgt tgctttagtt ctcgagattt tgcaactatt ttacagaaaa ccgtcagacg
     8221 tggattatac cttttcagcg gaccagtcgg atcaggcaag acttctctaa tgtatcggtt
     8281 ggctttggaa gaaaaattgc aagtgattac tatcgaagat cctgtagaga tagaagaacc
     8341 gttttttctg cagctacaga tcaatccgaa aatagcacag acttatgata cacttttgaa
     8401 actcgcatta cggcatcgtc cagacttgct aatcattggc gagataagag atgaatcaac
     8461 tgcacatgct gcggtaagag cagcactaac agggcaccgg gtttttgcaa ccgtacatgc
     8521 acgcaatctt gaaggtacat tggtcagaat ccatgaactg acaaagaaaa aagaagagct
     8581 atctgaatgt ttagctggtg tcatttatca agaacttttg gaagatgcca atcaccatcc
     8641 ttctgtttta tggagttatc aatttatgga ggaagaatca gtaaaaaaat catgggagga
     8701 aagttatgaa gaagctcagg aaaatatttg gcagtcagaa ctattctaaa ggattaacaa
     8761 gaagccagca aaaccagttt gcacaaacca tgggagaact gcttttatct ggttttagtc
     8821 tgcaagaatc cctttattta ttactcacga tccgttcgtt tccacctgtt attttggcaa
     8881 atatccaaca tcagctaaag gaagggcaag cgtttagtga ggtactttcg caaataggat
     8941 atggagcaga gcaactggta cagatcgagt tagctgaacg tcatgggaat ctgccgacaa
     9001 ctttgttgga aattgccaaa cagtttcggc ttgttgaagg atttcgcaat gatttgaaaa
     9061 agctgcttgc atatccgatg ctattgctca cctttttgct aggtatcttg tttagtatgc
     9121 ggttgttcgt tttgcctcag cttattggtt caggaatggt catgcaagag cattggggta
     9181 ttcagctgat acaagtcttt cattggtatg ttctactatt catcctagcg gttactctat
     9241 tggctttact agtaaggtat cgtctgatga agttgtctcc tgttgatcag agtgaatgga
     9301 taagcagaca attattgatt ggaccgatat attccttgta tcaatcggct tatttgtcac
     9361 tagagattgg aaagcttttt catgaaggtt tcgaattaag gcaaatcata gtctgcttaa
     9421 aggaaacgaa acaagaaagt ctgattcagc atcttgcctc taagttgatt caaggattgg
     9481 aggcaggtat gtcattggct gagcagttcc agaattatcg ttttctatca gaagaattca
     9541 gtaaaattgt tttacaggga gaggcaaagg gaagtttagg taaagaactg attttttaca
     9601 gcgaatggac aagaaaacag cttttcaaac gtcttcatca ctggatgcat tttattcagc
     9661 caatcatttt tttgggcgta gcggctttga ttttattagt ttatgccgct gttttattac
     9721 ctgtttacgg aagcatagag gaggttttgc catgaaaaag agaaaaatat cttattatag
     9781 cggttttaca ttgatcgaaa tgctaatcgt cttactgatc atcagtgtat tagtgttgtt
     9841 gttcgtccct aatttgtcgc gttataggaa tcatgtagac caagaaagtc gtgaagcgat
     9901 catccagttg gtagacacac aaaaagagct ctatgcgctt caaaataatg gaagagttcc
     9961 tactgtggag gaattgttga atgaaggcta tatcaaacga gaacatgcag aaatctatca
    10021 gcggccttga aggtaaggtt ttagcatcag gatatacgtt gtttgaatca ctcttactga
    10081 ttttattact tacaacgatc ctttcttttc cagttctcgc attttctgca tggaagaatg
    10141 aattggcagt ctatcaattt ttcggccaat ttgaaaaacg aatctattct acgcaaaaaa
    10201 tcgctattgt gaatcagatc caaacaggct tttattggaa tagtgaagag aatcaaatca
    10261 tttttcatgt tccgaatcca gataaaataa attgggaagt attagatatt cctgatgaga
    10321 ttaccttgaa acgccatgct tctattactt ttgctgctag aaccgggaat gaaagttcac
    10381 taaaagctta tcaattttat tgggaagaaa aagagcggac gattacgtat caattccaga
    10441 tagggagtgg tcgctataca aaaagaattg aataaaacag gatttgtttt gttggagtcc
    10501 cttacagcgc ttatgatcgc ttctgtctgt gtctacttag tgagctttgg ccagctgttt
    10561 ttgcttcagg cagaaaagaa aagtggggag gaactgctat ttattcgaat gatttatgaa
    10621 gatatcaaga cgcagcggat gtatcacaaa agaccagagc gaagggaaga aatgatccca
    10681 tacgatatcc aaattgtcga taataatgga gtaatcgaaa aagtgtttgt caatatggag
    10741 aaagaagcga tcagtattga aaaaacaagt aattccagca tttacgctga ttgaatgtct
    10801 aattggactg atgatattga gcagtctatt gctcacattc aatcttttga ttcagcaaac
    10861 catccaagta agtgaatttt tgcagcgtaa agatcaaaaa gagtggctaa tatttttagc
    10921 acaattagaa gaagaactca agagcagtca caatgtctct gtgaaaaatc agcaactgca
    10981 ctacacgatc gaggataaac agtatatcat cgaaagatat caggcaatga tacgtaaaag
    11041 aagaacttcc ggcggacatc aacctatgtt aacaagtatc actgagcttc aattattgga
    11101 aaaagaacac acaatttctt tttatgtaca ctttgaaaat ggagaagatg gatatgccat
    11161 atggacaaaa aacgatcagt agaaaatgtt ataagggctc tattttattt tctgtcttgc
    11221 ttttatttct tttatgtacg tttttattga tggcagcatt agaaagctac cgtttgtcaa
    11281 tggatcttaa tatacgaatc aaaaattatt atatagcaaa aataatgaag cagatggctt
    11341 tatcggaaca gtctacgctt gccgaaagtt cggaaggagt tttttactac acaactggat
    11401 ctgtaacata tcagtgggta caacagtccc tattcttaga ggtggaagtc tcaccgttta
    11461 tctttcggtt cacagaagaa gtaaaaaatg atacagatac tagtacagaa tgatggaatg
    11521 ttcgtgaaaa cgccctcttt tctgttataa cactgttttt aataaaaaaa tgtttgccgt
    11581 ttcacaaata aaaaacagtg aaaacgattg aaattttgtc aattgttcga tagaattaaa
    11641 caggtgaaaa aattgttata atatatctag aaatgaggtg caccatgtta ccagaaaaaa
    11701 tggaacaagg gtttaatcaa aacctggaag ctattcagct tttacagaat gcattgggaa
    11761 cttccttttt agaagcctat gtcgaaaatg cagaaaattt aatagatgat tatcaagtac
    11821 gtgtggtgga tggagtgccg acaaaagaga caacgcaacg gatcacagct ctttatgaag
    11881 agttgaagaa actttctttc gagccagaag aatggcgcag actgtctcaa ttacttttat
    11941 tgaagggcag ccagacagaa catttgcagg cgaaccatca actcactcct gatagtatcg
    12001 gttttttatt tgtttttctt attgaacaac tatacacaaa taaaaaagca ccggttaaga
    12061 ttctggatat tgcggcagga atgggcaact tgttattaac agttctttta aacctatcga
    12121 atgcggggta ccaaacagaa ggaattggtg tggatattga tgatacattg ttggctgtcg
    12181 cagcttctac aagtgatttg acacaagcaa atgttcaata ctttcatcaa gacgggttgc
    12241 aggaattatt aatagatcct gtcgattttg caatcagcga tttgccaatc ggttattatc
    12301 cgaatgacga aaaagcaaaa gagtttttaa caagtaccga agaaggccat agttatgcac
    12361 atcatttatt gctagagcaa tcaatgaaat atgtgaagcc ggatggtttt ggtttgtttt
    12421 tgatgccgag tggattttta gaaacggatc aaagtgaaga aatcaaaaaa tggtttaaag
    12481 aagaaggtta tcttcaagga atgattcaat tgccagatga attgttccgt aataaacaat
    12541 cgcaaaaaag tattttgatc ttacagaaaa aaggaccaca agcacaacaa gtaaaagaag
    12601 tcttgcttgt gaaacttgct tcattaaaag aaccagagaa ggtgacggaa tttttcaacg
    12661 agtttaaaaa ctggaaatca tctgctctgt aatcattcaa cgagaaggag agtcatatgt
    12721 ctaaaacaat tgcaatcaat gctgggagtt caagtttgaa atggcaatta tatcaaatgc
    12781 cagaagaaac cgtagttgcg aaagggatcg tcgaacgtat cggtttacaa gattctattt
    12841 ttaccatcaa gtacggcgat aatcaaaaat tcgaacaaat catggatatc gaaaaccacg
    12901 aagtagcagt aaaaatgctg ttagatcagt tgattgaact gcaaatttta agctcttatg
    12961 atgaaatcac cggagtaggg caccgtgttg ttcacggagg agaaacttat ggggattcag
    13021 tagtgatcga tgagaaagta atggaccgca ttgctgaatt agcagaattt gctcctttgc
    13081 ataatcctgc aaacttaatg gggatcaaag cgtttaaaaa gattttacct gacattttga
    13141 gtgtggctgt attcgataca tctttccact caacaatgcc aaagcaaaat tatttatata
    13201 gcttaccggt gtcttattat gaagatttca aagtaagaaa atatggcttc catggcacaa
    13261 gtcatcgtta tgtgtcggaa cgtgcggcaa aattattgaa caaaccgatc gaagaactaa
    13321 aaatcatcac ttgccactta ggaaatggtg tatcgatcac agcagtcgat ggaggtaaat
    13381 ccatggatac ttctatggga ttcacaccat tagctggggt gacaatgggt acacgttcag
    13441 gtgatatcga tccagctgtt ctcccatatt taatggaaaa attagagatt gatattgatg
    13501 aaatgatcaa tgttttgaac aagaaatctg gtctgctagg cctaacagga ttgtctagtg
    13561 atatgcgtga tcttgaaaag aactatgaaa aagaacatat tcgtttagct tatgacattt
    13621 tcgtggaccg catccgaaaa tacatcggcg gttatgtgac aacgatgaat ggtgttgatg
    13681 caattgtctt tactgctggt atcggcgaga atgacggaca tgtacgtagt gaaatcatca
    13741 aaggtatgtc ttggtttggt tgtgaaatcg atccagcgtt gaatgaattg cgtggtgaag
    13801 aagtagatat ctctacaaaa gaatcaaaag taagagtatt agtgatccca acagatgagg
    13861 aactaatgat tgcccgtgat gtggagcgtc tgcgcggcta agccaaagca ttcgttagga
    13921 taaaagatga aacgcatgca agagggaatt cttgcatgtg ttttttttgc ggagaagacc
    13981 gcaaaatggt aatttaactt caatttccct tcttttttac aggatcttct tagggaattt
    14041 tgcttggaaa agtggtcaaa agggaaaaga ctggcatttt atttattgat tttcaggaaa
    14101 atcccaatat tttattttca ttcatcttta taagggacat tacatatgta aaaagaaaaa
    14161 acatttttag atcagcctcg tgggctgtcg actttattct tcgctttatg tttagctaga
    14221 aaaccgatcc gaaacattca ttgatcgaat aataaaaact tgattttcca cctgtacttt
    14281 gcctgaatcg tgaaagcaca ggtatgaaaa tcaagttttt tgttgcgaaa aaacgtccta
    14341 gtcaatcagt tggccgagcg gctggcggct gatctgctcc tgatcaataa cgagtgcttc
    14401 ttggaagtgt tgctgcaaaa agtagcggtc atggctgact gctaggagcg ttccttgata
    14461 gtcttgcagc atttcttcaa tttcttctcg agcatagctg tcgaggtgat tggttggttc
    14521 atccaaaatc aggacgttga ttttttctaa aaagagtttc agcaacgcca aacggatttt
    14581 ttcaccaccg gataaatctt tgatccgttt acccacatcg ctttgataaa agccactttt
    14641 ggctaattgc cgtcgagcga cttcttcgtt tccagtcaat gtgatggcgt aagccagcaa
    14701 acggctatcg ggatcggcaa actgcagctg ctgcggcaaa taaccgattt gcaagctact
    14761 acctaatttg atggtgccac cgtaaggctt ttcctcaccg agtaataatt tgagtaaggt
    14821 tgattttcct gcaccattgt cgccgatgat ggctaaatga tctccacgat agactgcaaa
    14881 actgctgtct ttgaatagta cttgatcagc gtactgctgg tgcaagtttt gaatgatgaa
    14941 aacttctttg ccagattttc caccattaga caagctttgc agccgatttt tcgggggagg
    15001 tggcggtttg acgagtgtca gtttcgccag gcggcgttcc agttctttgg cttttttgaa
    15061 gaaggactca ttgtctcctt catgtgccca ctgacgaaaa cgacgaatca tgactttcaa
    15121 ccgctggact tctttttgct gcagttcgta attttttgtc agctcagcca agcgagcttc
    15181 tttcaagact cgaaaacggc tgtagtttcc gggatactca atcaatgcac cttcttccag
    15241 ttcccatgtt tttgtggtga cttgatcgag aaattgccga tcatgagaaa cgaccagaac
    15301 cgattttttt gtattctgta aatagttttc caaccagcga atactgttaa gatctaaatg
    15361 attggtcggt tcatcgagta aaagtaaatc ggcatcggct gctaaaattt tggctaaagc
    15421 gactttaact cgttcgcctc cgctaagttc tgttaaccgt gcttcctgac ggtgtggaat
    15481 ccctaagcct tgcaagatcg ctgcaatccg gtcttctaat acgtaaccgc ctagttcttc
    15541 aaagcgatgc tgcagctcac cgtaacgggc cagacacttc tctaagtttg tatctggttc
    15601 tgtcatcaat gcttcgtagc gactcatttg ctgtttgagg tcctgtatct cagcggcaga
    15661 atggagcaag tagtggttga cggtcgcttc ggaaactgta agttcttgtt cgaccgtccc
    15721 gatctttaag ccttttttgc gactgataac accgctgtcg acaccttctc tgccggtcaa
    15781 gatttgtaaa aaggttgatt tgccagttcc gttgataccg actaaggcaa ttttttcacc
    15841 agcttcaatt tgacaggata aatcctcaaa taatggattc ccgccgattg tttttttaat
    15901 agaaattgct tgtatgatca tgatctctct ccttgagacc actcaaaaag gccatggtta
    15961 tccctggcct gtgttattta aactcagatt atcatgagaa aaataccttg agatggccat
    16021 tgattttacg tgaattcaac tgttttggac aaacttgtcc cgtcaacagc aactgtaaaa
    16081 ccaattgcat ggctaaatgc gatatggtat cgttggtaat tttcattact tgttatttta
    16141 gtcatgcgca tcatagtatt ttccctcctt cgtgtagttg tcttttccag tgtacctgaa
    16201 agtgtcagaa agttcaacta gcgctgacat ttacttaata tttatcgatg tgtaattctg
    16261 tcagagagct ttttttatct gactgagggt aatgtctcgt ggaccacatc attgtattct
    16321 gagctaaacc agcgttcagg cgaaatcata tggtgtttga taaaaaactt tgtctacatg
    16381 acttcctttt gccatttgct taataccgtt gcattaaaca gctcttctct ttggaaatct
    16441 caccaacatc gcgttcagga gtatcgttgt ggttgcaatg gcaagcggta gcctttcatc
    16501 aattcttgaa tgatttaccg aatgtagcac ttgccttctc gcggtacccg aacccgaaat
    16561 aaaattttag tttggcgata aaatcggtat ccgccatcga tacttcatat tttttcgtat
    16621 cagattcatc ggaaacttcc acattgacga accaataagc tttggcatgc ttaggtcgtt
    16681 ttaaaccaca ccagggcgac taatcgccct ggtgttcact ttttttattt tacttgaact
    16741 cattgactgt tttcccttta ttttaaacat tataaagacc gatgagtgct tgccgcgtct
    16801 tttgttttta tcacggtttt ttgtgcaaaa aaacctgccg atagttggca ggtcgtctac
    16861 gtgttaagct ttggtgtggt ctttagctgg caattggttt tctaaatcag ttcggacaac
    16921 aagcacatcg caagctgcgt ttctaataac atattcagaa acagaaccaa taaataaacg
    16981 ttctacagca ttcaatcctg tggctcctaa cataatcaaa tctacttgat tatcttctgg
    17041 gatttctctg gcaataattt gttttggtga gccatattct acgacagagg ttacattatt
    17101 caagccagct ttcttcgcat tgctttcata atctgccaat gtttgctttg ccatttcagt
    17161 agcttgttct gcaagcattc catcaaagga tgaaacggtt tggaaagaac gtgtgtcaat
    17221 gacatgtgct aatagaagtt ctccgttatt tcggatagct acattgaccg cctttttaaa
    17281 agctaattca gcttcatcag aaccatctac ggcaaccatg atttttttgt attgttgtaa
    17341 cataagcatt cactcctcaa gtcaatcgta ttgtactctt ttattgtaga acactttagg
    17401 gaaaaagaga attatttact gctttggttc agcaattttt tttgcaaatc ggatactgaa
    17461 ggtggcagaa acaataatta cgatcagtaa aaagaccaag gcaataaagc gttgattgaa
    17521 aaaagctgtt aaaataccca ttacgcctaa aacagcatat gcagcaccgt aaaattgtag
    17581 gaatccttga tttttatcat ttttgttgat caatacaaaa aagatatcct gtttattaaa
    17641 taaataatag ctaacgaata ataatactaa agtggcgata atcattaaaa tcctaatcat
    17701 gaacaaatcc tccaaaataa gcaacaaata gaaaaagcaa tttgccaaga gcaaattgct
    17761 ttattcttta aaagatggta atctccgtta atgccgttgt ttgtcctgta gtattgatcc
    17821 cgcgaattca agcaggtggg tcccatggtc gtagcttcga actaccaaat gataaggcat
    17881 gttaccagca gtgacacaag acgggtccca agatatcaat aaaaatgttc ggtcaacaca
    17941 caaagaggac aattcgaaca tcacagattt cccacctcta tagtagcata tgaatttaaa
    18001 aagagcaatg agagagctcg cagaaacaga accgttttct tgtctagttt tttggaggat
    18061 gctttttcca ctcttttata cggtaatact gttgacccag agcctgttca tatttccctg
    18121 tatcttttgg ctgataatac tgagcattct tcagtttatc tggtaaatat tgctgattga
    18181 cccaagcctg atcaaaatga tgaggatact gataacccac gccacggttg agtgatttcg
    18241 cacctttgta atggctatct ctcaaatgat caggaacatc tccagctttg ccctctcgaa
    18301 tatcagcaag tgctgcatct aatgccatgt aggcagaatt ggattttggc gacaagcaaa
    18361 gatcgacgac gacgtctgct agtgggatac gtgcctcagg caatcccaat ttttcagcag
    18421 ctaatacagc gttcactgta cgagccgcag cagcaggatt acctaaacct atatcttcat
    18481 aaccgataac catcagacgc cggcaaatac ttgccagatc acctgcctca actaaacggg
    18541 cgagataatg aagtgcagca tccacatcac ttccacgaat cgatttttga aaagccgaaa
    18601 taacgtcata atgagcatct ccatttttgt catgggtaag agcttttctt tggacacatt
    18661 cttcaatgat cgacagtgta agatgaatcc ttccttcttt atctgaagga gtcgatagtg
    18721 tagccagttc cagcccattc aatgcactcc gcaaatcgcc gttcgttgca cgcgaaaggt
    18781 gaagaagagc atcttcgtct aactggattg cttgttgtcc aaggccgcgt tctttatccc
    18841 ttaaagcatg ttcgactgcc aactggatgt cttgttctgt taatggtttg acttcaaaga
    18901 tctgtgtacg gctgcggatc gctggattga tggtaatata aggattctca gtagtcgctc
    18961 cgatcaagat gattcggcca ctttctaaat gaggaagcag aaaatcctgt tttgttttat
    19021 ctaatcggtg tacttcatcc aataagagga tcactgtacc actcattttt gcttcttccg
    19081 ctacaacttg tagatccttt tttgaatctg tagcggcgtt tagcatgcga aatgcataat
    19141 tagtagagcc ggcgatcgca cttgcgatac tcgtttttcc agtaccagga ggtccatata
    19201 gaatcatgga agagagcatg cgagcatcga ccatgcggcg tatgattttt ccttccccga
    19261 ctagatgctg ctgaccaacg acttcatcga tcgttcgagg tctcatgcga taagccaatg
    19321 gctgttgcat aggattttcc tccttcttgt ttttacgtcc cttaattata tcatatttag
    19381 caagatgcct agaaagaaca gccttctgtt gttttgtttt catagcttat ccaactaata
    19441 ttgtgtatga taaagtaggt gagaaaaatg acggataaac aaaagataga tgaatttttt
    19501 tggaataaaa cgacgccaga agtggcacgg gatttattgg ggatgtattt ggagcatgac
    19561 acaccagaag gaagattagc tggatatatt gtagacgcgg aagcatacct aggtccagaa
    19621 gacgaggccg cccatagcta tggtttaaga agaacaccgc gtgtgcgggc aatgtatgaa
    19681 aaaccaggta cgatctacct ttacacgatg catactcatc ggattttgaa catcattact
    19741 cagccagaag ggattcctca aggagtaatg atacgtgcaa tcgaacccgc cgcaatgatt
    19801 gatcaaatga gtaaaaatcg tggcggaaaa actggtccag atatcagcaa cggtccggga
    19861 aaattagtgg aagcattagc aattcctcaa gaactttatg gtcagtctat agcagatagt
    19921 tcgttacgct tagtttttga gaaaaaaaag acaccaaaaa agatcaatgc tttgcctaga
    19981 atcggtatcc caaacaaagg tgtatggaca gaaaagccgt tgcgttttgt tgtgtcggga
    20041 aatccttata tctctttaca aagaaaaaac caaatcgaga aagattgggg ttggaggaaa
    20101 gaaaatgaaa aagaaggatc tattaacata tttagatgaa ataattgaaa aacaagtgac
    20161 agactatgat gtagctttag attgggatac aaaaaatcat acgatcgaga tcgttgttcg
    20221 cttgtttgca gaaaataaag cacaatttga gattgatgat gcagaaggga tcgtttcgca
    20281 agaaccaatt atcgaatttg aagacggcgt acttcttttt aatcctcaga aatctgtttt
    20341 tgatgaacgc aattatctag cagtaatccc ttatgaagga aaaaaagggt tggcaaaatc
    20401 agtagctgat tctttagtgg aatatctaaa tgaagtatta gctcaagggc aaagcgattt
    20461 gcttgatttt ttggatgaag acgatgacga agctgtattc gagcttcact gggataatca
    20521 acaactagca gaattagtag aagtaaaaca gcaaaatgaa gcagatactt atttaccgta
    20581 cccaagttat taaggagtga cagatatgaa atggaatgaa gtaaaagtag aaactgaaag
    20641 tgaagcagtc gaagcagttg ctaatatttt gatggaggca ggggcgagtg gtgtcgcgat
    20701 tgaagattct ttagatgttg aacattttca gtcggatcaa tatggtgaga ttttagataa
    20761 aaatgatttt acatcgctga aagaaggcgc actagtcatg gcttattttc cggaaacgac
    20821 tttcttaccg gaaatcttgc cttttatcaa agatcgtatc acacaattac ctgagtttgg
    20881 tctagctatt ggaaaaaata aagtaacagt tagtgaagta gaggaaagca actgggcaac
    20941 agcctggaag aaatactatc atccggtgcg tattacgcga atgctgacgg ttgcgccaag
    21001 ctgggaaaac taccagacag aagatcctct agaaaaaatt atcacactag atcctggtat
    21061 ggcatttggc acaggcactc atcccacgac ttccttgaca ttgacagcac tagaaacagt
    21121 cttgcgtggt ggtgaaacat tgctagatgt gggaactggg tcgggcgtgc taagtattgc
    21181 agcaaaatat cttggtgcaa aagatgtcta tgcctttgat ttagacgaag tagccgttcg
    21241 ttcggcgaaa gaaaatatgg atatgaatga aatagccaaa gatgtccatg tatcagctaa
    21301 cgatcttttg acaggaatcg agattgaaag tgatgtaatc gttgcgaaca ttttagcaga
    21361 tatcatctta ttgatgatcc cagatgcttg gcgtttactg aagcaaacag gcacgctgat
    21421 cgtttcagga atcattgaag agaagaagca aatggttctg gatgccatgt tagaacaagg
    21481 gtttatcgtg gatcaaattt tccagcaaaa agactggtat gcaattattt tgaaaaaacc
    21541 agaggtggaa tagatgcagc ggtatttttt aaaagaatca tatgaatcaa aagactattt
    21601 tgttttagaa ggggaaaact atcaccacat tgtacgggtt atgaggatgg aacccgagga
    21661 tgaagttttt ttggcattca atgatcaaat agccattgtt gcagaaatca cggagattac
    21721 tgaagaggct gtttatctga aagaaattaa aaaagaagaa aatcaaaagg aactgccaag
    21781 ttcgattacc atagcgagtg gctatcctaa aggggaaaag ctggattgga tcgttcagaa
    21841 atccactgaa ttaggagcgc aagcttttct tggtttcccg gcatcagcct ctgtcgttaa
    21901 atgggatgca aaaaaacgta tgaaacgaca acaacggctt gaaaagattg ctcaagaggc
    21961 agcggaacaa tcccatcggc agatcgtgcc atcagtagag ttattggaaa cgaaacaaga
    22021 tttatttgag cggctagatg attatgacgt ggtcttggtt gcttatgagg aatcagcaaa
    22081 gcaaggcgaa aaatcaaatg cagccaaaat tcttagtgaa acaaaaccag atagtcgaat
    22141 cttagctgtc tttggaccag aaggtggatt atcccgcgat gaagtcgatt attttgtaga
    22201 acacaaaggg atactttgtg gattaggacc aagaatcctt cgtacagaaa cagcacctct
    22261 ttatttatta agtgctgcta gctatcaatg ggaattaatg aatccttctt tcagctaacg
    22321 ttcttcatta ataaaagagt atcgacagaa agaattgaaa aaatagtcaa caatttgtat
    22381 aatagaaaca attatttata caatggatac gaaaaatcgt ttgaaaaagc ttttaaaaag
    22441 cgaacatttc cgtaaaaaaa cgtataactg cacggatttt gggacaatta tcaaacagat
    22501 atttgtcccg attcccgttt taccgaaaaa agaaaggggg atcgattcct gtgacaaaag
    22561 aagaaatttt aacgggaccc ggtgtcataa agctcgttag tcaatacatg ggtcccgaac
    22621 atgtagcatt tgttgagaaa gcatgcgaat acgcgactgc tgcacatgac ggacagttta
    22681 gaaaatcagg cgaaccctac attattcatc ctatccaagt cgcaggtata ttagcagatt
    22741 taaaaatgga tccccataca gtggctacag gcttcttaca tgatgttgtt gaagatacag
    22801 aaatcacttt agaagatctg agagaagaat ttggcgatga cgttgctatg ttagtggacg
    22861 gcgtaaccaa attagggaaa ataaaatata aatcccacga agagcagcta gcagaaaacc
    22921 accgaaagat gctgctagca atggctcaag atttacgagt tatcatggtc aaattagctg
    22981 atagactaca taacatgcgt acgttgaagc acctgcgaga agataagcaa agaaggatcg
    23041 ctcaggaaac tttagaaatc tatgcgcctc ttgcacatcg tctagggatc agccggatca
    23101 aatgggaatt agaagataca gcacttcgtt atctaaatcc aaaacagtat taccgtatcg
    23161 tccacttgat gcagacgaag agagaagaac gtgaaaaata cgtaagtggt actgttgaag
    23221 atattcgaat agcgacagaa gagctgggga tttttgcaga aatctatgga cggccaaaac
    23281 acatttattc aatctatcgt aaaatgaaag atcagaaaaa gcagttcaac gaaatttatg
    23341 acttgctagc tattcgagtg atcgtagatt caatcaagga ttgttatgct gtattaggag
    23401 caatccacac aaaatggaaa ccaatgcccg gcagatttaa ggattatatt gccatgccaa
    23461 aagctaatat gtaccaatct ttgcatacta ccgtgatcgg tccggcagga aatccggtag
    23521 aaattcaaat ccgaacacag gaaatgcatg aaatcgctga attcggggtt gctgcacact
    23581 gggcctataa agaaggaaaa aatgaaaaag tagaaccaga tggtatgacg aaacaattaa
    23641 gctggttcca tgagatactc gaacttcaag acgaaagcta tgatgcttct gaatttatgg
    23701 aaggcgtaaa aggagatatc tttagtgata aagtctacgt cttcacacca aaaggagacg
    23761 ttactgagtt accaaaagga tccggaccat tggactttgc atacagtatc catacagata
    23821 tcggtaacaa aaccactggt gcaaaagtaa atggcaaaat ggtgcagctt gattacaaat
    23881 tgaaaaacgg agatatcatt gagatcatga cttctccaaa ttcatttggc ccaagtcgcg
    23941 actggttgaa attagttgct actagcaaag caagaaataa gatcaaacgt ttcttcaaag
    24001 cccaagatcg agaagaaaat gtgatcaaag gccacgaatc cgtggtcaaa tgtattacag
    24061 atctaggatt tacgcctaaa gatattttga cgaagaacaa actgcaagaa gcactcgatc
    24121 gttttaatta tcaaacagaa gatgatctct atgcagctgt agggtatgga gaagttagcc
    24181 ccttgacgat ggccaatcgt ctgactgaaa aagaacgtaa agaacaaaaa atcgagcagc
    24241 aaaagcaaga agcagaagaa atcatgaatc agccgaaaaa agaacctgac aaaatgaaag
    24301 tacgtcatga aggtggcgtt gtcattcaag gggtagaaaa cttactaatt cgtatcagtc
    24361 gctgctgtaa tccgattcct ggtgatgata tcgttggtta tatcactaaa ggcagaggga
    24421 tatccattca tcgtcgagat tgtccgaatg ttcagcctga caaaccaaat gtagcagaac
    24481 gtttgattga agtcgaatgg gaagatacat cgaatacacg aaaagagtat gatgcagatt
    24541 tggaaattta cggctataat cgttcaggct tattgaatga tgtacttcaa acagtcaatg
    24601 cgctaacgaa aaatctcaac agcgttgaag cacggacgaa taaagataaa atggcgacga
    24661 tccatttgac ggttggtatc cagaatttat cccacctaaa gagtatcgtg gataaaatca
    24721 aagcagtacc tgatgtctac agtgtacgcc ggacgaatgg ataggaggac agatatgaga
    24781 gcagttgttc aacgggtaag taaagctgct gtgtcagtcg atcagcaaga aattggaaaa
    24841 attggctacg gcctacttgt tttattaggc attcatgaaa ccgatacgca aaaagatgtg
    24901 gactatctgg taaaaaaaat tgcacaaatg cgtatttttg aagatgaaca aggaaaaatg
    24961 aatattagtg tagaagatgt gggaggacaa attttaagta tctctcaatt cacactgttt
    25021 gcggatacga aaaaaggaaa tcgaccaagc tttgtggaag ccgcacgacc agaaacagct
    25081 attcctttat acgaatcatt caatgaagga atcagaagtc gcggcatcac agtcgctacc
    25141 ggacaattcg gagcagatat gtcggtttct ctcgtcaatg atggacctgt aacgatcatt
    25201 attgattcta aaaacaaata aagtaatctg gttttcacta gtaaaaacta tgaaacacgt
    25261 cgcttaagtt agactgataa actctaactt aagtggcttt tttgtctgca aaaagcgctt
    25321 cttttgtcag cagtcggaaa aaaagttaag cttaaattat acaagttatt ttttatagga
    25381 ggttgctgaa gatgaaagaa gtaccagtag tagatatcaa aatcacagat ttaaaaaaat
    25441 tgtatcaaaa aggatacaac atgttggagg agttacgcca tgaagcggac gctcccgtcg
    25501 tcaaagcaaa gattttcaat aaagaagcta tcacgatcta cggatcatca gcagcaaaag
    25561 tattttatga tccaaggaat ttcaaacgaa aaggtgctat gccaaaatta gtattgaaga
    25621 cactttttgg tcaaggtgga gtacagactt tggatggagc tgctcatcac catcggaaaa
    25681 atatttttat ggatctaatg acaccggaaa gaatggaaga ttatcatcgt atcttagata
    25741 agaatctgac acaagcactt gaagcacagc atggtcaatt tgaactattt gatttaagta
    25801 agatggtttt ctttacatct atttgcgagt gggcaggtat caatttatca gcgatttcta
    25861 aagatgaggt cgaaaaatta gcagaatatc aaatctctat gatcagcgga acgtttactt
    25921 ctccgattga tcacataaaa ggtgtcgaga atcgcaaaaa atcagaaaaa tgggcgcaag
    25981 gcttgattga agaagctcga caaaatcctg tggctggaaa agaaaatgtg gcattatatg
    26041 cttttgccaa tgccacagat ttagatggtc agcttttacc tctggaagtg gcagctgttg
    26101 aattattgaa catcatccgt ccaacggttg ctctaactgt gtgggcggca ttgatgggac
    26161 atgcactttt cagtagacca gatttgtatc agcaattaaa aaatgacttt tcgacgttac
    26221 aagatccgtt tattcaagaa atgagacgct attatccttt cttcccaatg ctacctgcga
    26281 tttcgctgaa agaagtagaa gtagatggtt atcgtatacc agaaggcagt tgggttattt
    26341 tagatttata tggaacagac catgatgaac gaacagttga agcgccagat tcctttatga
    26401 tcaaacggta tgtagggaaa gcaaaagata tttcctataa agaagaatat gagatgattg
    26461 cacaaggcgg gggaaatttt cgacaaatgc atcgctgtgc aggagaatgg atcactcttc
    26521 atagtctacg tgtgttttcc gatcagctag taaataagtt tgagttctct gtacctgaac
    26581 aagattggac gattccattc aatcagtttc cgacttatcc gaatagccga gcgctacttt
    26641 acaagaatta gattagcata aacttatcga aaaaaaggaa gatcaaacag tgctgatctt
    26701 ccttttttca tattactata aattgataag gtcaattgat caaaatccac gaaatgcttc
    26761 atcaatggtt tgataatctt cattggataa atgcaaatct aaagcttgga cattgtcaga
    26821 tacttgctct ggacgcttag ctccaggtat aactacagac actcgtggat tcttcatgta
    26881 ccaagctaaa acaagttgcg caggagtggc ttggtatctt ttagcaatgg ggcgaagtac
    26941 atcgacagcg gttaaaattt ctctgaaacg ttctccttgg aaatctggat ttctttttcg
    27001 aggatctcct tcaccaaatt gtttttcctc accaagttca tattttcctg tcagcaaacc
    27061 ggaagcaaga ggaaaatagg gaacaaaact gattttgttt ttttcaagat aagggaataa
    27121 ttctttttca gcctgccgat ggatcaaact gtatttatct tctactacat cgacatatcc
    27181 atctgcattc gcttctttca attgttctaa cgtgaagttt gacacaccga ctgctcggat
    27241 ttttcctgct tcttttaatt cgtgcaatgt agcaactgat tcattttttg gtgtgctttc
    27301 atccggaaag tggatataaa aaatgtcgat gtaatcagtt tgcagacgtt ttagtgcatc
    27361 ttccaccgat tgtttgagaa actcaggaga attatcaaat gttcgccctt tatttggtac
    27421 atgagcagct tttgtagcga tgacgacacg tgagcgatca tattcttttt ccttcagtac
    27481 ctcgccaatc agttcttcgg aacggccgtt tccgtaagca taagcggtat cgatcaaatt
    27541 gatcccgcta ttcaaagctg tacgaactac ttgttttcct gtctcatctt ccaaaccgtc
    27601 aaaaagatta tgtcctccaa cggcatttgc tcctaatcca agctgttctg cgtagacttg
    27661 tgaatgtccg attcttattt ctgccatagc tgattcctcc tttttgtcta gtctaaaaca
    27721 aaataccaaa aagctgaact aaaacgtttt tgtgagggga aatagtcaga tatctcttga
    27781 ctttgagact ggtttttagt aggttataag taatatcgaa tgtcaatgaa agagcgagta
    27841 agtttttgaa actttacaag agaggatcat cgaggctgaa aatgatctaa agtttcatta
    27901 gcctaaagac actctggaga tggacgagtg aaaagccgtc ccgcgtacga gcgttattcg
    27961 taagaggaaa gagaaatctt tcaaaattag gtggtaccgt gtatgaattt cattcaccct
    28021 tgttcatgat gaacaagggt gattttttta tttacatagc taagaaaggg agagaaaact
    28081 atgagtttcc aaagaccaaa aggaacaaat gatattttgc caggcgaatc agaaaaatgg
    28141 cagtttgtcg aagaaacagc acgtttatta ttcagagatt atcagtataa tgaaatgcgt
    28201 acaccgattt ttgaacacta tgaagtgata tcccgaagtg taggggatac aacggatatc
    28261 gtttcaaaag agatgtatga tttttatgac aaaggggaac gccatgtgac gcttcgacca
    28321 gaaggtacag caccaatcgt tcgttctttt gttgagcata aattgttcgg cccagagtat
    28381 gcgaaaccgt tcaaaacttt ttatatggga ccaatgtttc gctacgaacg ccctcaaaaa
    28441 ggacggttac gtcaattcca tcaaatcgga gtagaagcat ttggatcaga aaaccctgca
    28501 actgatgtgg agagcatggt gatggcactt gatttcttca aacagttggg gatcacgcaa
    28561 atccggctag tcatcaattc attaggtgat aaagaaacgc gtcaagccta tcgtcaagca
    28621 ttgatcgact atcttttacc ttttgaatca gagctgagtg aagactctaa acgccgcctt
    28681 catgaaaatc cattacgcgt attggacagt aaagacaaac gagatcaaaa atttgtggca
    28741 gaagctccat ctatcttaga ttatctaagc gagcctgctc aaaaacattt tgataccgtt
    28801 gtttccatgc tggatgcatt ggctgttcct tatgaaatcg acagtaatat ggttcgcgga
    28861 ctagattatt acacacatac gatttttgaa atcatgagtg acgcaccaaa aatgggggca
    28921 caagcaacga tttgcgcagg cggacgttat gacaatctag tggaagaact aggtggtcct
    28981 tcaacacctg gcttcggatt tgcaatgggt atcgagcgat tactcttgac tatggaggca
    29041 gaggaagtag ttatccctgc atttaatgag ttggatgctt acgtggtcgc actcggagac
    29101 gaaacaaata tcgaagcatt gaaagtggtc caagcgattc gaaactttgg tttttcagct
    29161 gaccgcgact tcatgaaccg taaagcaaaa gcgcaattta agacagcaga taaagcgaat
    29221 gccaaattag tattggtgat cggtgaagat gagcttgcta gtcaaacgat taatgtcaaa
    29281 gcaatggcaa gccgaaaaga aaaaagtttt ccattagaag agatatatga acattttgat
    29341 gaagtctatg atgaaatgac tttattcgag taggaggaaa aaaataaatg gcacaaagaa
    29401 cgatctattg cggattagtt tccgaacaac aattagaaca aacagttaca ttaaaaggat
    29461 gggtacaaaa aagacgagac cttgggggag taatctttat cgacctacgt gatcgtgaag
    29521 gaatcgttca aatcgtcttt aatcctgaaa tcaacaaaga agcatgggaa atcgcggata
    29581 aatgtcgcag tgaatacgtg atcgaagtga ctggggaagt tagaagacgc ggagaaaatg
    29641 cagtaaatcc taaaatggcc actggtgaat tcgaagtgat tgcaagtgaa atcgtgattt
    29701 tgaatcaagc aaaaaccccg ccatttcaaa ttgaagatga tcaagcaatc agtgacgaaa
    29761 tacgtttgaa atatcgttat ttggatctgc gtcgtccaaa aatgactaaa aacatcaaat
    29821 taagaaatgc gacaacaaaa gcgattcgtc attatttaga tgataatgac tttctcgata
    29881 tcgaaacacc ttacctaggg aaatctacac cagaaggcgc aagagactac ctagttcctt
    29941 cacgtgtcca tgctggacat ttctatgcgt tgccgcaatc tcctcaattg tttaaacaat
    30001 tgctgatgaa tgctggattc gaccgttatt atcaaatcgt tcgttgtttc cgcgatgaag
    30061 atttacgtgg agaccgtcag cctgaattta cgcaagtaga tattgaaaca acgttcttaa
    30121 cagcagaaga aatccaaact tacacagagg gattgattgc gaaggtaatg aaagaagttc
    30181 gcggtatcga agtcacattg ccatttcctc gtatgaccta tgatgaagca atggctcgct
    30241 acggcagcga caaaccggat acacgttttg atatggaatt gatcgatcta agcgatacag
    30301 tcaaagaagt agaattcaaa gtcttccaaa tggctcttga aaacggcggt gtcgtgaaag
    30361 cattgaatgc taaaggcgct gcagatcgct actcacgaaa agacatggat cagttaggtc
    30421 aatatgtagg acaattcgga gctaaggggc ttgcatggct gaaagtagaa gaagacggat
    30481 tgaaaggtcc aattgctaaa ttcatgggag aagcaacaga agcaatcatt aaagcaacag
    30541 atgcaaaacc aggtgacttg ctgatgtttg gcgcagataa aagtgaaatc gtcgctgctg
    30601 cattaggtgc tatccggaca cgtttaggaa aagaattagg actaattgat gaatcgaaat
    30661 tcaatttctt atgggtaact gattggccac aatttgaatt ttcagaagaa gaaggtcgat
    30721 atgtctctgc tcaccatcca ttcacgatgc caaaagaaga agatatcccg ttattggctg
    30781 aagaccctgc aaaagtctat gcagaagctt atgatatcgt cttgaacggt tatgaattag
    30841 gcggaggttc tatccgtatt catactcgtg agcttcaaga aaaagtacta gaaactctag
    30901 gctttacaaa agaacaaatg gaagaacaat ttggtttctt gttaacagct ttagattacg
    30961 gattccctcc acatggcggt attgcattag gattggaccg ttttgcaatg ttattagccg
    31021 gagaagataa tattcgtgaa gtcattgcct ttcctaaaaa cggaaaagca gcagatgtga
    31081 tgagtgatgc accaagtatg gtttcgcctt tacaattgtt cgaattgaat attgatgtaa
    31141 cgaatataga agaatagccg ataaaaaggt aaaaaggatt tgtcgaatac gcttcttttg
    31201 acaaccttga tttaattgaa aaacacttta taatgaagcc ataacatata aagcggggct
    31261 tttccatgaa aaaaacattc gaaaattggg cttatcatga ttacacgacc aagctttcgg
    31321 tatctatcgt ttatgcgttg atcgcatcag tcgcattgaa tttcttttat cagccaggac
    31381 atatttattc aagtggtatt actggtctag ctcagatttt gacgactttg tcaaaatcac
    31441 tgataggatt cgaagtaccg gtatcaacaa ctttgtattt actgaatata cctttgtttg
    31501 tattggcgtg gttaaaaatc gggaagaagt ttacaatttt cacttttatc acagtcactt
    31561 tgacctccct ttgtatccat attttaccgg aaacagtcct atctaccgat ccaatcatct
    31621 gtgcgttgtt tgggggggct gtgatgggac taggtattgg gctagcgttg agaaacggcc
    31681 tatcatcggg cggtctagat atcgtgagta tcacgattcg taaaaaaaca ggaaagtcga
    31741 ttggttctat ttcgatctac ttcaatgcat tgatcgtttt tgttgccgga attctatttg
    31801 gctggcaata tatgttttac agtacgttgt ctattttcgt cagtggaaaa gtaactgatg
    31861 tcgtttatac taaacaaaag aagatgcagg taatgatcgt aacgaaacat ccagaaaaag
    31921 tagtaaatga aatccaaaac tgtatgcgta gagggatcac gatcatcaat gaagcagaag
    31981 gtgcttataa gcatgataag cagacagtat tgatgacgat cgttacacga tacgaactgc
    32041 ctctacttag agaagcaatg aaagcttctg atccacaagc ttttgtaagt attgcagaaa
    32101 acgtccagat acttggtcgt ttctatgagg atggcattta gatcgagttt gacaaaaatt
    32161 catgaaatac tgctgtagac agacgttcgt ttgtctgcag tttttttcta ccatagtaga
    32221 atcagcaaag aaaaactgct tttttatttg aaattttctt aaagttgaaa aaaagcatgt
    32281 ttattttttt aaatttatgg gatgatagaa aaaaatagta gagaaaggac acgattctac
    32341 ttgctatttt cacttaatac ccgtatatta cgaatgaaaa aagtttatga aaagttggaa
    32401 tattgaatgg aaaaacaaaa aaggttaaaa aacagccgct acatcactgg gtttgatggg
    32461 ctccgttcat tagctgtggt gggtgttatc ttctatcacc ttctgccaac tagtatgaaa
    32521 ggcggctatt tgggcgttcc gatttttttc gtcgtatctg gttatttgat cacggatctg
    32581 ctgcggcagg aatgggaaca aaatggaaaa atcaatattt ggcaatttta tgtcagaaga
    32641 atgaagagac tctatccggc acttgttttt atgcttgtga cagcttcggc ttatatcact
    32701 ttgtttcagc gagggctgtt aaacaatctt cgaggagttg tggtcagcag cttactgtat
    32761 gtcaacaact ggtggcaaat caataacggt ttatcttatt tcgatcgatt tgctaatgag
    32821 tcaccgttta cgcatatctg gtctttagca gtagaaggtc aaaactattt ggtttggccg
    32881 atcttgtttg tattgttgat ggtatttgtt cgtaaaagaa aatggatctt ttatactgtg
    32941 ttaggtacat ccttcctctc cgccatcttg atgatgatct tgtatacacc aggaggcgat
    33001 ccaacccgtg tttattacgg taccgacact cgtctgtttt ctatatggtt gggaagtgcg
    33061 cttgcgtttg tttggccaag tacgcgttta aagaaaaaca tcccgaaaca agcgaaaaat
    33121 attctgaata tcgctggagg aatctcgctt ttggcactga ttctttgctt cttcttttta
    33181 gatgatcatt acaatttcat ctattacgga ggaatgctcc tagtgagtct gttatgcgta
    33241 gtgctagttg cagtgacagc acaccccgga gcaagtttga atcgatggct gacaaatcca
    33301 gtatttactt ggattggcaa acgaagctat ggcatttatc tgtatcagtt tccagttatg
    33361 attttttatg aagcaaaggt gactgatatt gccgatcatg ttttgttgca tactttagtg
    33421 gaaatcacat tgattctaat catcagtgaa ctttcttatc gatatgtgga gcgtccgcta
    33481 gcacgttttg attatggtcg tacattccaa gtgatgaaag gatggttcag caaaccgatc
    33541 atcagtaaga gcaaaccatg ggttgttcca ggcacattac ttgtagcaat tgcactcgtt
    33601 ggtttcgtta cggcaccgaa aaacgctgta acagccgatc aaaaacaact gcaggcaaaa
    33661 atcgctgaaa gtaaaaaatt agcagaagaa accagaaaca attcagaaaa caccactagt
    33721 tcggttgacc aagcgatcct tgataagtac gagttgtcca aggcacaagg gaataaggca
    33781 caaaaattag aactaacggc atttggtgat tcagttatgt tggatgctgc aacggatcta
    33841 caagaacttt atccaaaagt agtggtagat ggagatgtcg gacgacaatt atatgccagt
    33901 gtaccgtaca ttgaaaaatt aaaggaacaa gatttgttga aagacactgt tctgattgga
    33961 ctaggaacga atggctcatt ctcggaagct cagtttgata gtgtgatgga tgcaatcggt
    34021 gatcgaaaag tatactgggt caatgtccga gtaccgacga agcgctggca aaatgacgtg
    34081 aatgcgatgc ttgaacagat gacgaaaaaa tacgacaata tgacgctgat tgattggtac
    34141 agctacagta atgaccatag tgactggttt tatgatgatc aagtccatcc aaatcctgaa
    34201 gggatgacac attacattca cttagtcagc gaagccttgc taggaggaag ttcaagtacg
    34261 aacagcagtg agacaaacgt gacagaatga tagctacaaa aaacttcagg caaaaacatt
    34321 tgtttttgcc tgaagttttt ttatatttac cgtgttttta acattcatat agattcagga
    34381 agcaaaacgg ttgagtgtgt ctgtaaataa cgttcttttt gttttcgggt gagttttttg
    34441 aatgcagctt ctgcttttgt tgcttcgctt cttgaagaaa atacttctgc atggatcatc
    34501 ttaacaggtc ttcttttttg aagacgagta tatttagcac cagtaccatt gttatgttcc
    34561 tctaatcgtc tagaaagatc ggttgtatat ccaccataaa atgtctgatc tttacagaat
    34621 aatacgtaaa aataatgttc atttgccata gagcatctca cgaatctctg cagtgtattc
    34681 tccatccata ttgtaagtga tcaatggtgg agcgactttg aatccgtcta atttgccttc
    34741 tttgattcct tcaactaaca aaatatttgc ctcttttcca ggttttgggt aaacaaattg
    34801 gatcctttta ggtgcaattc gatagtcttc catgacctga atgatttcta agaaccgatc
    34861 aggacgatgg accatagtaa agcgtccatt tgtttttagt agcttacttg aaatatcgat
    34921 cacttcttct aacgtcgtat gaatctcatg acgggcgatt gccaggtgtt tattagggtt
    34981 cgttttattt gttggcagcc ctttgaaata aggtggatta cagacgacta agtcacaaga
    35041 attatgtcga acgacagata agctgtcttt cagatcgatg gtgtggacag tcatttgttc
    35101 atttaaatgg ttaagcgcga tactacgtct tgccatgtct gctagacgag gttgaagttc
    35161 gatagcgtcg atagccgcct gggttcgttt acttaaaaaa agtccaactg cgccatttcc
    35221 tgcacaaagg tcaacaatct tccctttttt aggtacacgg gaaaagtgag caagcagcac
    35281 agcatctaaa gaaaaagaaa acactttgga actttggata atcttgatat cttctgcgta
    35341 taattggtcg attcgttcgt cttcgtgaag catggattcc ctccaaaatg aaaaaaatag
    35401 tcgtctgtat tatactattt ttattaaaaa gaaccaaggt ggcttgtcaa acctctattt
    35461 tttatgcata ctatgaccat aagaagggaa aggaagagac tatgttttat cgatttatgc
    35521 gcggggtagt tcgagtacta ttagccttag ttaatggaaa tgcccgctat gagaataaag
    35581 aagttttacc gcaagatgag aattacatac tagttgctcc ccatcgtact tggtgggacc
    35641 cattatatct ggcggtagct gcagcaccca aggaattcag ctttatggca aaagaagaac
    35701 tgttcaaaaa tccagttctg cgatttatat taactcgatc caatgctttt ccagttaaaa
    35761 gagaaaatcc aggaccaagc gtcattaaaa cacctgtaaa gattttgaaa tcgacaaatt
    35821 tgagtttgat catgtttccc agtgggacaa gacatgctac agaacttaaa ggcggaatgg
    35881 cattgatttc cagaatgtct aaagcgaaaa tcgtgccagc tgtatatcaa ggtccgttga
    35941 cacttgggga tctgttcaag cgtcagagag tgacagtgcg tttcggcgaa ccaatcgact
    36001 tatcagatat caagaaaacg gataaagaag gtatggcgga gatcgaacga cgaacacaag
    36061 cagcttttga caaattggac aaagaagtga accctgattt caaatatgaa gtcaaaaaaa
    36121 aataaaatga taagtttatg cgtgggcggt cttttgaatc tactgtcctg ttcagttcag
    36181 actttttcaa tgaaaacgag ggagagacgt caagtctgcc ctctttttgc gttccaatat
    36241 gtaaaataga agacaggtgt catgtaatgg atcaaagtgt tataataatt agaaggacat
    36301 tttttgaggt gattgaatgc gttttttaca tacagccgat tggcatatcg gaaaaaaact
    36361 acaaggttat gacttgattg aagaccagcg tcatgtacta tcttctatac tagatatcgc
    36421 gaaagaagaa aaagtagagg caatcgtgat tgccggagac ttatatgata ggagtgtccc
    36481 agctgttgat gccgtagaat tatacaatga attgatggtc gattggaatt taaaggaaaa
    36541 gatcccgatt tttgctatat caggaaatca cgatagcagt acgagacttt cagcgggtac
    36601 gccatggttc agttattcga actatttttt gcgaacacag ctagcagaag catttgaacc
    36661 agtcgagttt aaaaacgtac aatttttctt tcttccttac tttgaaccaa ttgcagcgag
    36721 attatatttt gaagatgaca atatccgaac gatcaagcaa gcggtagcca aggtgataga
    36781 taaaatgcag gagctatttg attcagaaaa aaaacaagta ttgattagcc atttttttgt
    36841 aatgggaagt gtaaaatctg attcggaaac gaaaatcgaa gtaggcgggt tggattcgat
    36901 ccctggtgaa ctacttacac cgtttgatta tgtagcacta ggacatttgc ataatcaagc
    36961 tgctttgaga caggataatg ctcgctatag cggttcccca ttgaaattct ctttatctga
    37021 gatcaaccaa aaaaaaggcg tatggatcgt tgacctgaca acaggcctgg agttgaattt
    37081 tagggagatc gaacccctgc atgatattga agaaataaca gcgagtttca aagaattgct
    37141 ggatcctgcc ttttatcagt ccgtcaatcg ggagaattac atctatatct atctcactga
    37201 tagaacgatc atcccgaata tgatgaacca gcttcggcaa atatatcctc gtattttggg
    37261 gattgaacgg gcaaacggtc gagcagaaca aacaaagcgc aaacgaaaag tactagaaat
    37321 gaaagatcct caaaaattag cagaagcatt ttttagtgaa atgacggaag agcagctaac
    37381 tgcaaaccaa gaaaaatggc tcggagaaac gttgcaagaa atcatggaaa tggaatgatc
    37441 aagaatgaaa ccgaaaaaat tacaacttaa aaattttggt ccttttatca atgagaccgt
    37501 agatttttca cgtttgacag aagcaccgct ttttttgatc agcgggaaga caggagctgg
    37561 caaaacgacg atttttgatg ggatcacctt cgcacttttt ggtgaaactt ccggaagact
    37621 tcgctctgga aaagagatgc gttctttgtt tgctacacca gacgaagaaa caagcgtgac
    37681 tttttctttt gaacatcagc agatgagcta tgaaatcgaa cgaaaaccag aacaagtttt
    37741 agcaaaacga aaaggaaacg gaacaaaaaa acaggcagcc aaagtaacgt tgaccatttt
    37801 tgatgggaaa ggaaaagaaa taaaacaaat cacaaaacgt acagaagcag atcagttgat
    37861 cagagaactg atgaatctcg atgcgaaaca gttttctcaa atcgttttac taccccaagg
    37921 agaattccgt aattttttgg tttcatcaag cagtgataaa gagactgttt tacgtcattt
    37981 attcggtact caatttttcc aacagttcaa tgagcgatta aaagaaaaag caaaacaaca
    38041 gcaacaaaaa ttggatcatt tagagcaaga gctgcatctt ctgcaaaaaa ggtttgtttt
    38101 agtcaaagaa gaggaaccag cagcagggtt tgaagccgtt ttagcccaat ggacaaacca
    38161 tcaggcaata ctcgaaaaac aaatcacgga agaaaaagaa gctctaacgg aacttcagga
    38221 aaaacaaaag caactagaaa attcctacta tcgttttgaa agcttgaaaa aaagttatga
    38281 agaaaaaacg atattaataa acaagcaaaa ggaattagct gctcaaaaag acgaaataga
    38341 ggaaaagaaa cgatggattg ggtattatga atttacgcaa cgattagtcg aaccaatcca
    38401 gcgcctacaa gaaataaaag ttgaaaaaat agaactgtca caaaaaagta gtgagcaaac
    38461 aaagaaacta gcgatgacta cgcagaatta tgaagagtgg caaaaaaatg aagcaaaccg
    38521 cgtacgccga caaacaaaaa tcaaagaagc tgctcaaaaa ctgcaaaaca aacagatgat
    38581 ggtgccaatt gtcgaatcct tacgtagtaa aaaacaagac gcagaacaat taacaatttc
    38641 attggataaa gaagaattga atgccgagaa gctgtatcaa aatctcgcta tctatcagga
    38701 aagaactcga attcttcaag aaaatttact ggatcaggaa aaactgcaag aagatcgtct
    38761 tgcttttgga cagttaaaat atctagatga aaagcagcaa gaaatagaaa aacaaaaagc
    38821 aaaagacact gggtcgctcg cacagataag agaagaactc aaaaaagcaa ctgaagaaat
    38881 aacaaaaaat agtcagctat tgaaagaaca gacagaacaa gcagaacagc tgaaaagcca
    38941 atgggcaaag cagcaaattg ctcgtcttca gctttttttg cgtccagggg agccatgtct
    39001 tgtttgtgga tcaacggaac accccataca acaattaaaa cacgaacagc caaataagga
    39061 agatatctta aaagtagaac aacaactggc agaagctgag tctgctgtag aaagaactca
    39121 gcaaatcatt gccaaaagtg aagcacatga aaataatctt caacaacaat tatcagattt
    39181 agaacaaaaa atcatggcaa cgaatataca attggctgaa caagaagaac acttgcaaca
    39241 ggctttgaaa aaggcatttc ctgagataac agaacaaaaa acaaaaacaa ctcttgtagt
    39301 aatcgaacaa tctttagata gacgaaaaag caagatggcc aatgcaagaa tagagctgga
    39361 agaaataaga caacaagcag aaaagctcga acaacaatta gctgtctaca aacagcagca
    39421 gacagaaaaa aataatcagc tccagcaact gcaaggagaa atcaaaagtt tagaacaaca
    39481 attgcaagat acggatagta actgtttaga agaggagata cgacgacttg aaaaacagtt
    39541 agaagaagac tcgaatcaac tagctgttga gcagaaagca ggagtgcaat tgttgcaaga
    39601 tcttcatacg cttcggacac agcttgatct tcaacatgaa caaatagaaa aaatagatga
    39661 aaaaatagaa aaggaacaag aaagaatagc taaaaagtta gaaagccagt cgtatttttc
    39721 aacaattgaa gaaatctgtg catttgcaca acagcaagca caatataaag aaaaccaacg
    39781 tacagttact tcttatcatg aagagcaatt agtgacagct gaccggctgc gtcaattaga
    39841 aaatatccag ctaactgaga cattcccaga tacagaagag atcagccaac agttagaaga
    39901 aataagacgt atgatcgaaa taaagcaaga aaagatatac ggtttacaag aacaaaaaat
    39961 tagtaatcaa aaaatctacg atgaatgtct ttcgatttat cacacaagcc agacgaaatt
    40021 agatgagctt acgcaattac agcagctttc gcaaacattc aacggagaaa atcctaagaa
    40081 gactagtttg gaacggtatg tgcttcaggt ttatcttcaa gaagtgttac aagtagcaaa
    40141 tgatcatctc caacgtttaa cgaaaaatcg ttatcaattt gagctagcgg ataccattgg
    40201 cagttatcga gggaaaaccg gattagaaat caatatctat gatgatcagg caggtatgtc
    40261 tcgaagtgcg cataccctgt ctggcggtga gagttttatt gcagcacttt ctttagcatt
    40321 agctcttgcc gatgtgatcc agacacaagc tggtggtgta gcaatcgatg cattgtttat
    40381 tgatgaagga tttgggtcat tagatgaaga agctttggaa atggcaatgg aagctttaga
    40441 aacgatcgaa agtgaaggaa gaatgatcgg catcattagt catgtaagag aattgaaaga
    40501 acgagtatta caacaaataa gaattgatac agaaggtagc ggacaaagca aaatacgcta
    40561 tcaacttgga taaaaaggga gattggtaac tatgaaatgg agtattccag aaaaagtcat
    40621 tgcacgtgga cgtcaatact tgcaagaagg ccgagtgtta tcggttgtcc ctgaccaaga
    40681 agaaaacgtg tggcatgcag aagtcttggg cagtgaattg tatatggttg atttggatgg
    40741 tacagcaaaa gagatagatt actgccaatg tccctattgg gaggaacata aatattgtaa
    40801 gcatacagtt gctgtggaac tttatttacg gtcgaaaaat ctatctcgta tcatgaaaaa
    40861 agaccagcca atgctagaac cggtaaaagc aacaagtgag ggagaaatca ttgcaaaagg
    40921 tttttctcgt ctaaaaacac aaaacaatcc tcaagcggtg caacctttga ttattgaata
    40981 ccaagtagaa acgattgaga ctaatcagta tcacccagag ctttctattt tggcacttta
    41041 cttgcgtatc ggttcattgg catcaccgaa aaaaacatat atcgtaaaaa acatctatga
    41101 ttttttacaa gcttacacag aaaaagaaac ttacactgtt aataaacagt accagtttcg
    41161 tctagataaa cgggcgtttc aaaaagaaga tcaaaaaata ctcacgcatc ttgcaggaag
    41221 tgctcagacg catcaattat taggtacgaa cggcttacaa gtcaaaggaa aactagataa
    41281 aagatatctg cttctcccag tagaacaagc ccgcttcctg ttagagcaga tgaatcagac
    41341 tacacgtttg catctgcaga taaatgaaca aaacgatcaa ggaatacaat tttccgatca
    41401 aaacaaacct ttatcattca aagtggaaaa atttggagaa gattatttgc tgcaagcatt
    41461 gaatgatttt gattttttct ttatgcatta tcagtgggga gttatccaag ggacatttta
    41521 ttctctgacg aaatatcaac aaacggttta tcaaacttgg aaacaattga ttcgccgatt
    41581 ggagaaacca gaagtagtgt tcaagaaaaa agaattaccg tctttgttta aagagattat
    41641 ccctctgctg tcagagatcg gcgacgtagc tattgcccct gcagtagaag aggaagtagc
    41701 agatatcccc gtcgaattta ttttcttttt ccgaaaagca aaaggaaaaa tccaagctcg
    41761 agtcgatttc gtctatggtg aagtcatcta ttcgactgac ccgaagcatg aggtctcgac
    41821 agaacaggct tttcaggtgt tacgtgacac agtagaagag aaacgagtac ttgatctatt
    41881 cagaatgtat cgctaccaga aaaatgaaac tggttatgaa cgtccattgc caagcgggga
    41941 agaactatat gcctttttcc gcacagaact atctgtcttc cgtcagtttg gtgaagtcag
    42001 acttggaaga aaattgcgag agttgtattt agatgcgcat aaacatcaac cgaaaatcga
    42061 agtaaccgag accggttcat ggctcgatat tcgattcgat gtgacaggga tagaggagca
    42121 agaaatcgat catgtcctgc aaagcttgct gagaaatgat gctttttata cattagaaaa
    42181 tggtcaggtt ctttcttttg attcagaaga atttcaacaa acaagccaag tgttgcaaca
    42241 attacgggaa tcgatacgta cagaagaagg aacgatccat gtacctaaaa atcaaggatt
    42301 gatcattcaa aatcaattgg aaaaaagcaa tgctactttt agtgaatcgt tccaaacgat
    42361 ggtacaagat ctcattcatc cagaaagata ccaggcacag cttcccaaag gattgaatgc
    42421 aacgatgaga gattatcaaa agcaaggttt tcgatggttg aagatgttag gtcattatca
    42481 gtttggcggt attttagccg atgaaatggg acttgggaaa acactacaga caattgcctt
    42541 tttactttcg gaaaaagaag aacggaaaag cttctctgct ttgatcgtag cgcctgcgag
    42601 cttaatttac aactggcagg cagaggtgag aaaattcgcc ccttctttaa gtatccaagt
    42661 aatcaatggg aataaaaaag aacgtgaaga attactggct aaagacacag atatccgagt
    42721 gacttcttat gccagcttaa gacaggatct agctaattat cagtcgcaaa aaattgatta
    42781 tttgattctt gatgaggcac aaatggtcaa aaatagcagt acgaaaactg cacaagcatt
    42841 gagagaatta gctgtacctc agcggtttgc actgagtggg acaccaatcg agaataattt
    42901 agaagaattg tggtcattgt ttgcaacgat tatgccagga tttttcccga ctaaaacaaa
    42961 attcagggaa cttgccgcag aagaaattgc gcaaatgatt cgaccgttta ttttacggcg
    43021 agataaacaa actgtgttga aagacttgcc ggaaaaaaca gagatgaatc tatattctgc
    43081 acttacagaa gaacaaaaaa ctgtttattt agcttacttg cgtcaaatgc gtgaagaaat
    43141 cacatcaatg gattctgaag cattcaagaa aaaccggatc gggatacttg ctggtctgac
    43201 aagactgcga caaatttgct gcgatcctcg tctgtttatt gaagattacc aaggcggttc
    43261 cggcaagctc gaacaagtaa aagatctact ggtagctgcc aaagagaaca aacgaagagt
    43321 tttgctgttt tctcaattta cagggatgct gactatcttg caagaagagt tagccgagct
    43381 agggatctcg acattttatt taagaggcag tacgaaacca caagatcggt taagtatggt
    43441 agacgcattt aatgctggcg aaaaagatgt ttttctgatt tccttaaagg ctgggggaac
    43501 tggattgaat ctcacgggag cagatacggt catcttgtat gacctttggt ggaatcctgc
    43561 cattgaagaa caagctgctg gacgtgcaca tcggatcgga caaaaaaatg tggtagaagt
    43621 gtggcgtatg atctctgaag gaacgattga ggaacgcatg gattcactcc agcaagaaaa
    43681 acgcgaactg ttccaaaaag tgatccaagg taatgaagaa cagttgacga aactgactga
    43741 agaagacatc cgcatgattt taagtgtagg agaaatcgag gagtaagaga ctcgaaaaag
    43801 cgttcagtaa tgggtaagaa agcctttcta aagaagcgat tgtttatttg atttaaaaaa
    43861 tagcaaggag gctgggattc cattttatcc cagcttcctt gctatcattt ttttatttct
    43921 atttttaaag gttatacaaa gattgtcttc attgtctcta acagctgatc aaaagaagaa
    43981 atctcgatat cgcaaattgg agtctgttca attttgcgtt ctcgatggtt gaaccaaagc
    44041 gcttgccagt tagcactttt tgcacctaga acatcattgt cgtaattatc gccaacgtat
    44101 aaggtctctt ctggaagcat atgaaattct ttctcagcca gctgaaaaat ctctttttct
    44161 ggtttttgga aacctgttgc ttgagaaatg agcatattgc gggaaggaat ccaattgttc
    44221 aattgaagtt gcttcagttt ttttgtctga tggtcagtcg gcccatttgt gataattcct
    44281 aatgggacat tcttttcctt caagaaatcg agggtttttt tgacctcctc atgcaagcag
    44341 atattatcaa gttcttcctc gtaaattttt tgaaataaga ggccatcttc ttccgtaata
    44401 tgagggtagt ctaaatcttt tagtgattgg ctgatccgat gtgctcgcat atattctagt
    44461 gtccaatctc ctgccattac ttttgggaag ttttcatcac tatgatggcg gaaccggata
    44521 tatagtggat gcatatctgc atctgaaaca agcggaacga ctcttttgac cgcgtttcga
    44581 aatggctgct gctgatcata catcgtatca tcaacatcaa acacaactga tttaatcaaa
    44641 attttacacg cctttcggtt ttcattgatt ttttcacaaa tccttgacta ttgtaacaga
    44701 aaaaattgtc taaaaaagct gataaataaa ggtttttctt actatatttc tatttccttg
    44761 acagaataag gtttttatat ttcagttttt ttcactaaaa atcgtgaaac acgtcaataa
    44821 gtttgatgaa caaattaatc attatggtag aagtcgattg atttatttta atgcaatctc
    44881 tgtggaattt tcgaaagatt tattttttta atacagtctc aatataacta ttcaaacata
    44941 aaataacgtt atttgattta tttgtttata gtaaatttta tttagtaatc attgctttaa
    45001 aatactacgc ttatataaca gagaaaataa gcgttataat aaagaacagt attatttaaa
    45061 atgacagaaa acattactat taaagaaata aaaaacataa aaaatcttaa gaaatcggtt
    45121 tcatttagct tttgagataa aataatagta cagttttata cgctgtttca tatgtttaga
    45181 aaatttgaat tagatttgaa aactctaatt tttaaatgat aaaaaaagcg agaatgctgg
    45241 ttttactgta tattaacctt agataacttt cattttttta aaaaaattat gaaaaaaagg
    45301 tagctattta aaagttgatt atgtataata gaaacagatg ggagattatt atgatcttct
    45361 gttacaaaaa agtgattctt atcacgaaaa ggagtggtgc acgttgttaa cattatatac
    45421 ttccccaagt tgtacttcct gcagaaaggc tcgtgcgtgg ttgcaagaac atcagattcc
    45481 atttgttgaa cgtaatattt tttcagaacc attgaacagt tctgaattaa aagcgatttt
    45541 acaaatgaca gaagacggaa cagaagaaat catctcgaca cgttccaaag tattccaaaa
    45601 actgaacatg gatttagatg atctgccgtt acaagaatta ttggaacttg tgcaaaacaa
    45661 tcctggattg cttcgccgtc caatcatgat tgatgataaa cgtctgcaag ttggttttaa
    45721 tgaagatgaa attcgtcggt tcctaccgcg cgatgtacga caattagaat tacgtcaagc
    45781 acaattgatg gctggattat agaaggataa tacgaaactt ggaaaaga
//
LOCUS       DAPBAF010000022        42888 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.022, whole genome shotgun sequence.
ACCESSION   DAPBAF010000022 DAPBAF010000000
VERSION     DAPBAF010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 42888)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42888)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42888
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.022"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            6..305
                     /locus_tag="RD451_001395"
     CDS             6..305
                     /locus_tag="RD451_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDT7566663.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            378..1739
                     /locus_tag="RD451_001396"
     CDS             378..1739
                     /locus_tag="RD451_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HDT7566664.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFMSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLPFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGIITMPIYLYGATYLAPILSDLAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1761..2021
                     /locus_tag="RD451_001397"
     CDS             1761..2021
                     /locus_tag="RD451_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566665.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2035..2787
                     /locus_tag="RD451_001398"
     CDS             2035..2787
                     /locus_tag="RD451_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HDT7566666.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2881..3486)
                     /locus_tag="RD451_001399"
     CDS             complement(2881..3486)
                     /locus_tag="RD451_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDT7566667.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIKQAREWTDHLLTK"
     gene            complement(3539..4513)
                     /locus_tag="RD451_001400"
     CDS             complement(3539..4513)
                     /locus_tag="RD451_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HDT7566668.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DGPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4891..5610)
                     /locus_tag="RD451_001401"
     CDS             complement(4891..5610)
                     /locus_tag="RD451_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDT7566669.1"
                     /translation="MPKYEEIANILRERIRSKEYPLDSFLPNQVDLVKEFGASRMTIK
                     KAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEYEGLSLQMKRRHRSLKSQIIH
                     FDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVLEHTFMPVHLVPGLKKEHLLA
                     SIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAENDPVLEVQQVVYLKDGQPIE
                     YSSSRNRFDVRNYSVLDVRST"
     gene            complement(5737..7008)
                     /gene="celB"
                     /locus_tag="RD451_001402"
     CDS             complement(5737..7008)
                     /gene="celB"
                     /locus_tag="RD451_001402"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HDT7566670.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7161..8558
                     /locus_tag="RD451_001403"
     CDS             7161..8558
                     /locus_tag="RD451_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDT7566671.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWDHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSHLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKVIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGIIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8639..9079
                     /locus_tag="RD451_001404"
     CDS             8639..9079
                     /locus_tag="RD451_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HDT7566672.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9227..9553
                     /locus_tag="RD451_001405"
     CDS             9227..9553
                     /locus_tag="RD451_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HDT7566673.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9554..10303
                     /locus_tag="RD451_001406"
     CDS             9554..10303
                     /locus_tag="RD451_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566674.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10383..10838)
                     /locus_tag="RD451_001407"
     CDS             complement(10383..10838)
                     /locus_tag="RD451_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HDT7566675.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNLENSTDLDDEFLNYYI"
     gene            complement(11265..11540)
                     /locus_tag="RD451_001408"
     CDS             complement(11265..11540)
                     /locus_tag="RD451_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566676.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
     gene            11834..12649
                     /gene="thiD"
                     /locus_tag="RD451_001409"
     CDS             11834..12649
                     /gene="thiD"
                     /locus_tag="RD451_001409"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HDT7566677.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKNAQQETVNDYVLFESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
     gene            complement(12978..14429)
                     /gene="cls"
                     /locus_tag="RD451_001410"
     CDS             complement(12978..14429)
                     /gene="cls"
                     /locus_tag="RD451_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HDT7566678.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            14770..17436
                     /locus_tag="RD451_001411"
     CDS             14770..17436
                     /locus_tag="RD451_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HDT7566679.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNK
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            17800..18552
                     /locus_tag="RD451_001412"
     CDS             17800..18552
                     /locus_tag="RD451_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDT7566680.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(18574..19728)
                     /locus_tag="RD451_001413"
     CDS             complement(18574..19728)
                     /locus_tag="RD451_001413"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HDT7566681.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYGLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            19913..22354
                     /locus_tag="RD451_001414"
     CDS             19913..22354
                     /locus_tag="RD451_001414"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HDT7566682.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKQYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     NVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
     gene            complement(22684..23388)
                     /locus_tag="RD451_001415"
     CDS             complement(22684..23388)
                     /locus_tag="RD451_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566683.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
     gene            complement(23575..23820)
                     /locus_tag="RD451_001416"
     CDS             complement(23575..23820)
                     /locus_tag="RD451_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566684.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            complement(23837..24688)
                     /locus_tag="RD451_001417"
     CDS             complement(23837..24688)
                     /locus_tag="RD451_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HDT7566685.1"
                     /translation="MNSLTSTYRLSNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQTTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            24854..25858
                     /locus_tag="RD451_001418"
     CDS             24854..25858
                     /locus_tag="RD451_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HDT7566686.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
     gene            complement(26099..26455)
                     /locus_tag="RD451_001419"
     CDS             complement(26099..26455)
                     /locus_tag="RD451_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HDT7566687.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
     gene            26823..28010
                     /gene="tuf"
                     /locus_tag="RD451_001420"
     CDS             26823..28010
                     /gene="tuf"
                     /locus_tag="RD451_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HDT7566688.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            complement(28198..30789)
                     /gene="mprF"
                     /locus_tag="RD451_001421"
     CDS             complement(28198..30789)
                     /gene="mprF"
                     /locus_tag="RD451_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HDT7566689.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLISVLPMVGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDS
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(30815..31576)
                     /locus_tag="RD451_001422"
     CDS             complement(30815..31576)
                     /locus_tag="RD451_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDT7566690.1"
                     /translation="MTDIIVILYTVGDYVKKEKKYAKMPDGSEIYYEKSGQGFPLFLL
                     HGNDGSGRFFSEQVPVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEK
                     IDQADFLGFSDGANLALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVW
                     LLSLFRPSLRKNLLVIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKT
                     IPKASFVLVKEQGHELARKDPERFNREVLQFLSET"
     gene            31854..32375
                     /locus_tag="RD451_001423"
     CDS             31854..32375
                     /locus_tag="RD451_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HDT7566691.1"
                     /translation="MESYQIEITTAAKNYHMENYENLIKAIILTESKGKGTDLMQSSE
                     SLHGEAEIIDNPADSIDQGVKYLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHG
                     GENTVELAEAYSKDVLSPLLGNEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKM
                     NEKIIETYEKVFK"
     gene            32434..33294
                     /locus_tag="RD451_001424"
     CDS             32434..33294
                     /locus_tag="RD451_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HDT7566692.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLCGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            33479..35794
                     /locus_tag="RD451_001425"
     CDS             33479..35794
                     /locus_tag="RD451_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HDT7566693.1"
                     /translation="MNGLTQQEVVQKMASGQQNDYQEDASKSTKQIFSDNILTLFNFL
                     NFGIGICLLFVGAYSNMAYLAIIVVNIVIGIYQEIHARNLVRKLSIVSQSEVLVIRDG
                     KEQSISTKELVLGDLVKIGAGEQIPADLQVISGRAEANEALLTGESDLIVKETGAELL
                     SGSFLTSGSVMAEVIRVGADNYAVRLTSEAKTHKAIRSELVDSIRKVSKFTSFVIIPL
                     GIILFLEALFIRDASIKISVIASAAALLGMLPKGLVLLISIALTTGVTKLAKKRILVQ
                     DMYSIETLAHVDTLCLDKTGTITEGKMSIQRVEALHPLYEKAIPEIMGTYLAESSDNN
                     ITMRAMRDYFELSNRYDVTNKVAFSSDRKWGAMEFPELGVVYVGAPERLVEEDRLPDS
                     LKTAQANGYRVLMLGIAPNQQLNEEKPAFVEPVALFEIDDPIRKNAQETLAYLHEEGV
                     DLKVISGDNPFTVSNIARRAGLPNYDAYVDLSQITEEMEVREAAHRYTVFGRVSPQQK
                     KLLVNELKESGRTVAMTGDGVNDVLALREADCSIAMAEGDGATRQIANLVLLDSDFTT
                     LPEVLFEGRRVVNNVTKVSGIFFIKTIYSFILSIICAVTAIGFPFIPIQITLIDLAIE
                     GYPSFFLSFEQDKRKITYRYLPTALINALPNALLVVVNIIAVYLLGKTFAWGNAETTT
                     LMYYLLIGISCMAVVKACYPFNPLRIFLAVTTIVGIYVAAMLFHGILEVNLGLGESVG
                     YFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            35976..37817
                     /locus_tag="RD451_001426"
     CDS             35976..37817
                     /locus_tag="RD451_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HDT7566694.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            37841..38950
                     /gene="rpoD"
                     /locus_tag="RD451_001427"
     CDS             37841..38950
                     /gene="rpoD"
                     /locus_tag="RD451_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HDT7566695.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            39170..41269
                     /locus_tag="RD451_001428"
     CDS             39170..41269
                     /locus_tag="RD451_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HDT7566696.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
     gene            41465..42328
                     /locus_tag="RD451_001429"
     CDS             41465..42328
                     /locus_tag="RD451_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDT7566697.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            42433..>42888
                     /locus_tag="RD451_001430"
     CDS             42433..>42888
                     /locus_tag="RD451_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HDT7566698.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEK"
BASE COUNT        14097 a         7511 c         8869 g        12411 t
ORIGIN      
        1 aaaaaatgaa aaatcggtta attgtcgcat gtggaagtgg agtagcaacg agtcagacaa
       61 tcgctagtaa gatccaaagt atgttagaag atgacggcat cgcatttcct gtagaagcag
      121 ttgattacaa atcgattcaa aatgagcttc taactgctgg aatctatgtg tatgtcgcac
      181 aacctgatga ggaagtactt gaacaagcaa aagatttggg tattgaagta tttccaggaa
      241 ttccattttt aactggaatg ggtgtagaac ctatttatga cagtatcaaa gagttagtac
      301 agtaaaggag gattgttgga taaaaaagtt ggttcatagt tttatttact atatttagaa
      361 agaaagaagg tttatttatg gaagttttcc aaaccattat caattatgtt ttgaacttag
      421 gatcagccat ttttgttccc ctgattattt tgatacttgg attgttggca gggatgaaat
      481 taaaaaaagc attcatgtct gctttgactt tagggattgc ttttagcgga atgtctatgg
      541 tcattggcta tatgtctaac gcagtaagtc cagcatcaga agcattggct aaaaatacgg
      601 gaatcagttt gcctgcactt gatcttgggt ggacaggtgc agcaagcatc acatggtcgt
      661 ggagttatgc ttttatattt tttgcagtaa cgattggggt caattttgta ctgttacttt
      721 ttaattggac gaagacgtta aatgttgata tgtggaatgt ttgggggaaa gctttaactg
      781 cttatttagt ttattatgtt tccggtagtt tggctgcagg ctttcttact gcaatggtcc
      841 aagttatatt ggaattaaag cttggtgata tgtttcaaaa acatatacaa gatctcacag
      901 ggattccatt agtaacagtg actcatttta tgacatctgc cgctgtcttg ttgctgcctt
      961 tcaatatgat catggataaa attcctgctt taaataaacg agcggatacg aatgcattga
     1021 agaagaaaat tgggatcttc tctgaaaact ctgtaatggg attcattatt ggattggggc
     1081 ttggctttgc tgctgcgtat ggcgtttcag gttctcttaa tctagcgatc caaacagcta
     1141 cagcattaag tttgtttcct atgatctcta aaatgttcat gcaatctttg tctcctctag
     1201 cagacgctat gtcagaattt atgaaaaagc ggtttaagga tcgtgaagta tatatcggat
     1261 tggactggcc gatattagct ggtcgttcag aaatttgggt tactgctatt ttacttgttc
     1321 ctgtgtttat tggttatgcc attattttgc caggaaacca agtattgcca ttagcaggga
     1381 ttatcaacta ttcgattgcg gtcggcggat tacttttaac aggaggaaac ttggctcgta
     1441 tgctgatctt gggaatcatc actatgccta tttatttgta cggggccact taccttgcgc
     1501 caatactcag tgatttagca gaaaaaagcg gagcagtcga gggaatcaag aaaggacagt
     1561 tgatcacatg gtcatccata gaagggccgg agttcagggt tttatttgcg gaggcattta
     1621 ataggaatat tctcgctatt gtaggatgcg tgatttttct aggactgttt gttctacttt
     1681 ataaatatat gataaaagcg aaagtaccga gtgaacgtta tgctgaacta caaaaatagc
     1741 attgaaatgg tgggaaagta atgaaaagag aagagacaga taaaataaaa tggacagtcg
     1801 ctctttgtgg tacacttctg ctatttctat atggactctt tactcagaat atcatcatca
     1861 atctattggt catttttttc gcactagtga tctataaata tggaaatcac gttttattca
     1921 gagagtacga tgaaaaaaga aaacggaaaa tagaagaatc aatgaaaata aaagaagcta
     1981 ccaaagaaat attgagagaa aaaagtttta taaaaagata atggaggggt cattatgtca
     2041 gatggacgta tgttatttga gagagaacga caggacatgg cacgtatcgt aagagtgatt
     2101 ttcgaaagga aaaacacaaa tgtcgcagga gggaattttt cctttaaaac cactgatgat
     2161 caagggaaag actacatcat catgacgccg accatgatgt cagaagccta tctaggagag
     2221 atttctcctg cacaggttct agtagtagaa ccaagaacgc gtagaatcgt tgacggagtc
     2281 ggtcatttaa ctcgtgaaat caatatgcat gaagcgatgt atgagactaa tccagctatc
     2341 aaagctgtcc tacatgctca tgcgcctaat gcaatgttct gggcgactac tgggttgcct
     2401 atgcctaatt tgacagaagc cacagctaaa gtaaaagaga ttcctgtcat ggactttgag
     2461 cctaattgct ctgaagaact tgctgaattg acaagcgact atgtaaaaaa acagcatctc
     2521 gaattaccgc atatgttgct gctcaactct catggcgtat tgatcaacac aggtggagaa
     2581 tcaggaatcg aagctatcca taaagcactg caaatccttg atacagttga atggaatgca
     2641 gaaattgcct acaagcagac gatttttcaa gcattaggga ttactgacgg tttttattca
     2701 aaaggtgaga aaatcggggg attggaagag ttgaaacata aaacggctat ttataataaa
     2761 tctgttattg cagctggtgg agactaacct atctgacaca aaaaactacg actttcacaa
     2821 aatctgatcc agatcgatat ctgcttcagg ttgtattatg taagtcgtag ttcttttctt
     2881 ttatttagtt aagaggtggt ctgtccattc cctcgcttgc ttgatttcgt ccatcgtcaa
     2941 ctgatgacct gttacagtta gctgaatagt cacatttgct tggcgtgttt cgaattgatc
     3001 ggccaattct ttaaaggaag caggggaaac gattggatcg ttatcaccat aagaaatcca
     3061 gacggtttta tcctctaatg tggaacggct ttgatgaaca cctagagaca tcggatggaa
     3121 aaacaaccct ttatttagct cggtctcacg ctccaataat aaatgagcag cgatgtttgc
     3181 gccatttgaa tagccgacaa gcagccagtc acttaacggt atcagttctt tttcgctgat
     3241 ttctttgatt ttttcatgga gtttatctgt ttctttttcc aaactgtcca ggtcgaattg
     3301 attcaatcca ttacgcttga aaaaacgatt catcccatct tcttggaccg tgccacgaaa
     3361 agaaagcaat gtactgtttg gtgcaagaaa gtgagcgata tccagtaaag aatgttcatc
     3421 gccacctgtg ccatgaagta agatcaaatg cttgccactt gttccttttt caaaaatgta
     3481 ggtcattttg ttccctcttt tctgtttcta tagatgcaaa tgaagtagca tgaagagatt
     3541 attcacgttt tttatttgca tcacttgtat cgaaaggacg gacataagct tcaatggctt
     3601 cacgacgttc ttctaagaat ggaggaagag atagtttttc tcctgctgat tctgctggtt
     3661 catcttcaag gaatccagga ccatcagttg ctaattcaaa cagtacgtga tgagcggcta
     3721 ggaagtactc agattggaaa tagaaacgat cgacgaaacc agaatttggc aattcaatct
     3781 tattgattac ttgaatccag tattccaatg cttctttgtc tgctacacgc aatgctaagt
     3841 gatggatatt tccaaatcct tcgattgctt ttggcaagtc tgtccgatgt tcaataatga
     3901 tgcttgcacc atttccccct tcaccgattt caaataagta gaaatctcct gaatggtctg
     3961 tttctttgaa tcctaagatt ttttcaagaa tcaagcggat atgctctaat tgactgacac
     4021 ggacaaagac aggtccaagt cctgtgatcg caaactctgt cggtacattg ctgtttttcc
     4081 aaggaatgcc agctgctaca ccttgattgt tttcgtcaga gatcaattga taatactgat
     4141 tatcgaaatc ttcaaattcg atatattttt tgccgaaacg ttcattgatt gctgaatgag
     4201 taacgtcata tttttcaaaa cgttccaacc aaaagtctaa tgctgcgtca cttggcacac
     4261 ggaaagaagc acgagagatc gtatctgttc ctttttttcc ttttggctga tttggaaaat
     4321 caaagaaagt catatctgtt cctggcgcac cagtatcgtc tgtaaagtaa agatggtaag
     4381 tttcgatgtc atcttggtta actgtttttt tgattaagcg cattcctaaa atatctgtaa
     4441 aaaagcggta gatttttgta gcgctagatg tcattgctgt gacgtggtga attcctctga
     4501 tttgtgtatc catgataaat ttcctcctgt taacttacaa aaagtaagta gttgatttag
     4561 acatagtata gagggtgcat ctctattttg caattaattt gtcttctaaa gtatcaggaa
     4621 ggaatcaaga atggaaaaga ggagggacgg atcaataaaa taaaaagact tacgactagc
     4681 tgtatcgatt tcaaaaaaac tagctttaaa aagctaactt tagaatcatt acgggtggtc
     4741 ataagtcttt ttatgctgag ttattttttc atttttgagc taatgcttag gatagaatag
     4801 aatgttgatt tcacgatctc ttcttgttac ttgaaactgc ttaccactgt cacgatctct
     4861 tggtaaacgg ctttttcaca acctctttgg ttaagttgaa cgcacatcca gcacagaata
     4921 gttccgaaca tcaaatcggt ttcggctgga agaatattca atcggctgtc catctttgag
     4981 atagacgact tgctgaactt ccagtacagg atcgttttct gcacagttca aatattgctg
     5041 atcatattca tcacttttat ctgcagaaat agcacgataa gcccctgcaa aatggacatt
     5101 caattcttga tgaagatgat catagataga ggctaacaaa tgttcttttt ttaaacccgg
     5161 cacaagatgg actggcataa aggtatgctc taaaacatat ggctcgccat ctaagatcct
     5221 taaccggtga atattgtaga caggttgctc ggcatcgatc atcaatcgtt cttggatata
     5281 ttgattaggg aattcaacat caaaatgaat gatttgactc ttcaaagaac gatgtctgcg
     5341 tttcatttgg agactcaaac cttcatactc gttagcgggc gatgtgtctt tttgcataaa
     5401 tggatgattc aagattttcg ttcctgatcc tcgctgcgaa tagacaagtc cttccattgc
     5461 taagatattg atggcttttt tgattgtcat ccggctcgca ccaaattctt ttaccaagtc
     5521 gacttgatta ggcaaaaaac tatcgagagg atactctttt gaacggatac gttctcttaa
     5581 aatatttgcg atttcttcgt attttggcac gttattcacc tcttctagag tataacgaaa
     5641 gattatgctt ccgacaactc gaagtagcat ctggaacatt gtttattcga aaaaagaggt
     5701 catgacaagt ttttgtcaca accccttaat gatctattaa gcaatatcta aatctggttg
     5761 tttatctagt actttcagga atgggtacca gataaaggca acgatgacaa agtcgatgac
     5821 ttgcagcata ccaccaagcc atgaatttgt tgctaagaca ccgcttgcaa tgattggcac
     5881 agtccatgga acagagacgc cagttggtgc agggacaagt ccagcagcca ttaccaaata
     5941 attgaacgtc gttacgatta gaggtgccac aacccaagga ataaggattg ttgcattcaa
     6001 tacgatcggt agaccgaaga tcgctggttc atttacattg aaaataccag gtgctaaagc
     6061 taatcgtcca acatcacgat actgtttctt tttaagaaca aaggccatca ataaaacgac
     6121 agctaaagtc attccagagc caccaatacc aacagtgaag gtttccatga atggttttgt
     6181 gatgatgtgt ggtaattctt ttccatgttg ataagcttct aagttatcaa gcatcagtgt
     6241 attccaaatc gggtccatta cagagttgac gatgatttgt ccgtgaagtc cgaagaacca
     6301 taagaattgg acaaagaaca aagcaatcaa tgttgcaggt aaactacttc ccaaaccagt
     6361 taatggtttt tggatcactt cataaacgac gtcatgtaag ttagcattga aaataccagt
     6421 catcacagca ttgattacta agaaaatagt tagtgtcact acagcaggga tcaaagcggc
     6481 aaatgatttt gttactgcag gcggaactcc atcaggcatt ttgatctgcc agccgcgttt
     6541 cgtgattctg cagtagattt ctccagccaa gaaagcagcg atcattccaa tgaacattcc
     6601 ttttgcgcca agacgatcaa gtgaaagcac accagtcaca tcttcaccgc cagcggtttt
     6661 cattgcaaaa ggcgtaagaa tcaagaagct ggcaaaagac acggcaccac cgaaaatacc
     6721 ttcaacgtca taagattttg ataaataata gccgatacca aaagtaacaa aaaccgacat
     6781 gatgctcatt gttgcatttt gcccattacc gaataaattc gataaagttc cctttgttgc
     6841 gtcactgaaa aaaggcaagt tattgataac gacaacgatc gaaccgaaca tcgttaaagg
     6901 gaaggaaagc atgaaagcat cccgcagcac tgtaaggtaa cgattttgcc ctaataaatt
     6961 agctaagggc atgattttct cagaaagctt gtccataaaa ccgttcattt ttattcacct
     7021 caaatttatt tgcaatcgat tacatacaaa gtataacgcc aaaaatttta aatgtctagt
     7081 cattttcata aaaagtattg atttattttt tagggttcgt tatgattacg gtatcaagaa
     7141 aaaagagagg aagtaaaaaa atgaaaacct acacattccc agaaaatttt tggtggggtt
     7201 ctgctgctag cggaccgcaa acagaaggaa gagtaagtga tgatggtaaa ggagaaaata
     7261 tttgggatca ttggtatgaa ttagagcctg aaaaattctt cgatcaagta ggacctgaaa
     7321 aaacttcgca agtttacaca aaatacaaag aagatgttca gttaatgaaa gaaactggcc
     7381 ataacacatt tcgtacatct atccaatgga gtcatttgat tccagaaggg acaggtgaaa
     7441 tcaatcaaaa agctgtttct ttttatcgag attattttac tgaattgctg gataatggta
     7501 ttgaaccttt tgtgaacctt taccatttcg atatgccact accactgcaa gaaaaaggcg
     7561 gatggttatc aagagaaacg gtcgacgctt atgtttctta tgcagcagcg tgctttgaac
     7621 tgtttggaga tctggtcaaa aaatggttta ctcataatga accaatcgta cctgtagaag
     7681 gaggctactt gtatcaattc cactatccaa atcatatcaa tatgaaagaa gcggtccaag
     7741 taggctatca tgagaatcta gcaagcgcaa aggtaatcaa agcctaccat gaaggcggac
     7801 atgatggtga gatcggaatc atcttgaatc tgacaccaag ctatccgaga gatgaaacga
     7861 acccagaaga tgtaaaagcg gcgaagatcg ctgacgcatt cttcaaccga tcattccttg
     7921 accctgcagt gaaaggagag tttccacaag agttgatcga aattgtcaaa gaattggcta
     7981 taatgccaga gatccatgaa ggagacctag aactcatccg tgaaaacacg attgacctgc
     8041 taggaatcaa ttactatcag cctcgtcgaa tcaaagcaaa agaaactcca atcaatcacg
     8101 aacatagccc catgccagat gattattttg ataattacga catgcccaat aaaaaaatga
     8161 atccatatcg tggatgggaa atttacgaaa aaggaatcta tgatatttta acgaatacaa
     8221 gagaaaacta tggtaatatc aaatgctata tttctgaaaa tgggatgggg gtcgaaggag
     8281 aagaacgatt tgttaacagc gaaggaatta ttgaagatga ttaccggatc gagtttgtta
     8341 cggatcattt gaaatacgtc catcaagcaa tccaagaagg aaccaattgt gtgggttacc
     8401 acatgtggac atgtatggac aactggtctt ggacaaatgc ttataagaat cgctatggct
     8461 ttatcgctgt tgatttggca caagacggta aacggacgat caaaaaatca ggtcgctggt
     8521 ttaaaacggt ctctgaaaaa aacggatttg atgcctgata ttttttgata aaacgttcac
     8581 aaaatgtttg ttctaacact gtaatcgtgc tacactaaca gtgaaggagg cgtttacaat
     8641 ggtagatact tatcgtaata ttttagtagc aattgatggt tctgaaaagg cagaaaaagc
     8701 atttcttgag gcaatcacga ttgccaaacg aaatcaggca acgttgcaca tcctgtatgt
     8761 caatgaagta acaggcaatt actttggtga ttttgcattt gttacaacaa gccttcagga
     8821 agaattggat gaggttgcgg aaaaccagat gaaagaacat cgaaacttgg caattgaaaa
     8881 aggcctgaca gatatcgaga catatgttct ttacggttat ccaaagacac tgattgctaa
     8941 tttccatgaa tcgaaagaac caatcgatct gattgtcatg ggggcgacag gtctgaatgc
     9001 ggtagaacgt gcactagtag gttccactac ttcctatgta gtcaaccacg catcatgtaa
     9061 cgtcatggtt gtaaaataaa taaattaagg gaacagaaag caaaaaagca taacgcttct
     9121 tttgctttct gttcctttta tttttttgta aaaaattact ttacctgatg aagtaatcat
     9181 gctattctaa ttacaacgac agatggagta atatggagga aagaaaatga tttcaagtga
     9241 tggaatacgc ggatacaatg atgcgattat tttatcgatc cttaacaaaa acgattctta
     9301 tggatatgaa atttctaaaa cgattcgtga gaggacaaat gattcctatg tgatcaaaga
     9361 gacaacactt tactccgttt ttgcccgttt agaaaagaat caactgattg tttcgtatcc
     9421 tggagaagtg actcatggaa aaaagcggac atattataaa atcactgaaa tagggcgtaa
     9481 tcttttagaa gaaaaaaagc aagagtggct gacgacgaaa gacgtagtcg atcaattttt
     9541 ggagggaaat taaatggata caatccgtaa ttatttagac agtcttttta tcggagtacc
     9601 tcaaagtacc gagatagata agctgaaaac tgatttgttg gcaaatatgg aagaccatta
     9661 tcatgaattg atgggagaag gaaaaaatga acaggaggcc atcggtacag taatttcgac
     9721 atttggttca atcgatgaat tattagaaga actagatgtc gaaaaaaaac atcaagctga
     9781 cgagacggaa acaaacacag cttctattta tttaagcgaa gcagaaaact actggaaaga
     9841 atacagagcg gcaagtctcc aagtggcatc aggtgttcta ttcattagct tatcttttgc
     9901 aagttttctt ttcttttgtt cagcaggata tgtgttcatg ggtatttctt gtctgatttt
     9961 cggtatagca ttagctgtcg gtttttttat tgcttctggt atgaaaatca cacgtttaaa
    10021 tcactttttg caccatcgga aaatacctga aaaagtatta gcagaagcaa aagaaaaaga
    10081 agaagagtat cagcgaagtt ttggcttctc actgattgca ggaattggat tatgtatttt
    10141 ttcacttttc ccacttttgg cttctttaat gtggtatatg gatggtagta tcggtgcctc
    10201 tatatttttt gttacggtag gaacgggtgt cttcttgatc atttatggca gtctagtccg
    10261 tcattcttat cgtcaattca ctcaaagcgc ttattactgg tgaatgtatt cagatttgta
    10321 aaaatattct atttatccgg cgtagaaaaa aagactgtga cacgcttttg tcacagtctt
    10381 ttttatatat aataatttaa aaattcatca tctaaatccg tagaattttc tagattgctt
    10441 acccatgtaa aatcgttata gacagatttc agttgacttc tgcgccattg tacagggata
    10501 aaaagacgca tgctatcttc attgaatccg actaataatt tctttccgtc agtaatgatg
    10561 ggacgttgta acaaagtaaa atgcgagacg atcagatcga caagctctga ggtcgtacat
    10621 tggtcgattt ggtctttcaa atttttataa tcaatcgagc gtttagctaa tagatcgtca
    10681 aatccgtttt ctgttaatga caataaataa aatatctctt tccttgttaa aggctgttta
    10741 ggtgtgaaaa ttcgttctct gtaaggcatt tgatggtctt tcagccagtt tgccatcaga
    10801 tggtaactat gtgtgcgaga agaatagatc gtaagcataa aaaaactcct taaatagtcc
    10861 attaatttgt tagatctgtt gagataaata ataggtaagg agctgtgcat aagcattgat
    10921 caaaacaacc caaacatcat tagaaataac tttctaaagt cttaaacttg cgacgagaaa
    10981 caactagact aatagaaaaa atgtcttagc catttggctt cctgtttgtt tttttgctta
    11041 tgctgcagct cctcgggaaa gggttctaac aatttgaaga aggttgatga ttgatctagt
    11101 ttaaattgtg tgaaatttga aatctggtgt ttttactaga tgaatcacct aacaactatg
    11161 attataactt atagaacttc tgttttgcat tcggttttgt tatagttgtt ataaagtttt
    11221 attttattac agaacatttt taattaataa agaacagtta gaagttaaaa ttgctgattc
    11281 acatagagtt tatgacttct tggaaattct ttttcaatca gttttttcat ctgtttatga
    11341 aattcttttt tttcagtaaa cataaaggtt tgggtatcgt aaccttcttc atgtaggaaa
    11401 tagattattc ctttttctgt gttttgcgta taagctttta tactcctgtc ttttttgaaa
    11461 gaacagatcg tatagccatc tatttggtct ggtagtcgtt tgattttctt caaaatgact
    11521 tttttatcct caagtttcat ttttttcacc tgactttatt tttttcatat ggaaatcata
    11581 gcgcctttgg ttatatgaaa acaagaagga tactgaaata tatataaatc aaatagtggt
    11641 tatttattat tagaatagcg aatacaaata aacgaccact attttctgat ttattgcaaa
    11701 tgttttttca aataaatttg attaccaaga aaaggtagtg gtatatttac tgagggatac
    11761 tttgaaaaac atatgataga aacagtaaca gtattatgaa aaatcttttt ataaaaatgg
    11821 aggaatcgat ttgatggaag atcagtatgt acaagcaatg acgatcgcag gatcagatag
    11881 cgatggaagc gcagggatgc aagcagatat gcatacattc tttacaagaa atgtttacgg
    11941 tgtttctgtc atgaccgcat gtgttgcagg taattcttac ggaatcggag caagtgtgac
    12001 attgccaaca gattttatcg acaaagaatt tgaactgatt gcgaaggact ttcaaatacg
    12061 tgcagctaaa acaggtatgc tagcagattc aaagttgatt gagacagttg taaaaaatta
    12121 ccaaaaatat gattttggac cattagtcgt ggatcccgta atcgtaacga aacatggaaa
    12181 tcttttacta gaagaatctg ctttgcaaag cttgaaagaa aagcttgtcc ctttggccga
    12241 agtactgaca cctaattttt atgaagcaga aaagctgact ggacggacat tagcagctga
    12301 agaagatttt gtgcaagcag caaaagaact gcaagatatg ggtgcaaaaa acgttatgat
    12361 caaaggacat catgctaaaa atgcgcagca agaaacagtc aatgactacg tattgttcga
    12421 atcaggaaaa tcattttggt taaatgcacc attttatcct accgaccgga tcaacggaac
    12481 tggcgattcg ctatctgcat gtattgcagc tgagttagcg aaaggaaaaa cagttgaaca
    12541 agcgatccga ttggcaaaag actatgtaaa ccgtgcaatt cgtgaagaaa taaatgtagg
    12601 gcacaaatat ggccccatca atcattgggc agctggtgaa ttagagtaaa agaaagaagt
    12661 tgtgaaaaag ttgccctgca tcaagtaata agaacagcca agtaaaaaca gcttcttatg
    12721 tttttaactt ggttggactt attaccgcag atgcaagctt ttgaacaccg tttaagaaag
    12781 aggtcgtgag cctgccgtcc agctccgagt cacaaggaac aagttcaaaa aacagcttct
    12841 catgtttgtt gaatattgtg acttgtgacc gaggagttgg caggagaaca ccgtttgttc
    12901 ggaagaaggg actgtgacaa gatttttgtc acagtccctt taatcttagt atatttttct
    12961 ctacttgaat aaaaaaatta taggattgga gaaaataatc gagaaatttg ttgcttgaat
    13021 aatagccagt tagacatttc cttgactgtt tcagttgtca tggatgaaca atgtgtctca
    13081 tcttctttga actgagtagc aagttcttct aaaaactcag gatcgtaaat gacagcactt
    13141 gtttcaaaat tcaatcggta gctacgaata tcttgatttg ctgaacctac catgcagatt
    13201 tcatcatcca ttatcaatgt ttttgcatgg aggaagccgt tctcatagac aaggatttgt
    13261 acattttcct tgatcagctg ccgagcataa tattgtgttg ctcgataaat aaaaggatga
    13321 tccggtttgt tgggaatcat gattttcaca tctacaccag aggcagttgc gatttttaaa
    13381 gcagcaatga cactttcatc aggaacaagg taaggtgtct gtatccaaac acgtttttta
    13441 gcagaagtaa tcaatttgat aaatgaaagc ttgatttgtt ccctttcgtt attcggtccg
    13501 cttgaaacaa gctggatgga tgtatcagca agcttagatt catctcgatc tgctttttta
    13561 aagaaataat tcaaatgata gccgaccttt ttttcttcag gtaccgagac gttccagtct
    13621 gttaagaagc gaagctggag caaagaagaa gcggcaccga aaatccgtat atgcgtatcg
    13681 cgccaatagc cgaatttttt tgttgtattt acatattgat tggcaatatt gaaaccaccg
    13741 gtataactaa tctttccatc gatcacaacg atttttcggt gatcatggta attcaatcgg
    13801 aaacgaagta atgccctttg tgaggtaaca aatgtatgga catgtccacc atttttgatt
    13861 agacgattga aatcttttgc ttttgtgcca tgagagccaa atgcatcata taatattcga
    13921 acttccacgc cttctgcggc tttttcttct aaaacatgta agacttgctg gccgatatta
    13981 tctgtcacaa atgcgtaata ttcgatatgg atcgaatgtt tggctttttt tagatcttga
    14041 agcagtgaat ccaatttctc ttgtccgtct gtgagaagag tgacagaatt cattcttgtc
    14101 agcggcatac gatttaatga agagaagaag tcaacaaatt gctgtttgtc tttatcgccc
    14161 atgtcaggat cgtaatgttc aatggtatct cctctaaaag actgaaagtt ttctaattct
    14221 ttcaagtcac tttgtcggag atagaatttt ttcttatccg ttaatccacg tccgaaaaat
    14281 aaatataata caaagcccac cccaggaagg gcaaacaata ctaagagcca tgcccaaatg
    14341 gctgctacat ctcggggttt gatcaaaata gccaccaaag caataagtgc atttaataga
    14401 taaagggcgg ttataatact agataccaca aaaatgttcc tccttacata caataacatt
    14461 agtatagcat gatagaagaa agaagcctac caaggtgaat atacttttca ctcctttcat
    14521 gaaaatgtag gtaaatcggg ctaaagtagt tgctttttgt aggttaataa ggtaggatat
    14581 tagtacagtt gaatatctcc ttaggggagt aaccggcaac gtttgttgcg ataatatcaa
    14641 cagtaagtta accaaatggt tttctggtat tgtatgaaat ggtgagacct aagacaaatg
    14701 cgtatttgtc ttaggtctct tttttttcag acaggactag ggccaagatc aaaaaatggg
    14761 ggatgaaatt tggaaaacaa ggaacaagca caacaagcgg tctataaaga aacgatcgac
    14821 tcgttgatgc agcaaacgca gagctcaacc gatggattga gcaccacgca agcgaaggaa
    14881 aaattagaaa gagatggctt gaaccagcta aaagaaaagc cgaagaagcc aacttggaaa
    14941 ttgttcttag aaactttcaa agatgcaatg gttatcgtat tgctgattgt cgcactgatt
    15001 cagatggtca tgggtgacta catcgaattc ttagttattt ttgcagtatt gatgttgaat
    15061 tctataatca gtgttgtcca aacaaaaaaa gcagaaggtt ctttagaagc gttgaaaaac
    15121 ctttcagcgc ccgatgctcg agtgattcgt gatggtaagg aaaaaacgat tccggcaaac
    15181 gaacttgtgg taggagatat cgtgttgtta gacgcaggcg attatgtacc tgctgatgga
    15241 cgtttactag atgcgggatc attaaaagta gatgaaggta tgctgacagg agagtcgact
    15301 tctgcagaaa aagaagtaac ggatatcaca agtacggtac caatcggaga tcgtacaaat
    15361 atggtattca gtggaacgat cgtaacttac ggacgcggta aattcttagt gacttcaact
    15421 gggaataata cggagatcgg acaagttgct ggccttttgg aatcaacaac tgagcaagtc
    15481 actccgttac aacgaggtct ggataaattc agtaaaaaac taagtttggc tattttggca
    15541 ttgtctttat tgattttagg tatccaactg tttcgtattt atcttggaga aggtacagga
    15601 gatatgactg cagatatcgt cagcgcagtg atgtttgccg tagccgtagc cgtagctgct
    15661 attccagaag cattacagtc tatcgtaaca atcgtgttat ctttgggaac gaataaaatg
    15721 gcaaaacgtc atgccattat tcggaagctt ccagcagttg aaacacttgg ttcgacaagt
    15781 atcatctgta cagataagac tggtacattg acacaaaaca aaatgacagt tgttgactac
    15841 tttttaggta atggcgatac tggggatttc acaaatgacc cttcaaaatg gacagctgac
    15901 gaacgtcgct tgatcgaaat cagtgtttta gcgaatgatg catcgatcag tgaagacggt
    15961 actaaattgg gcgaccctac ggaagtagcg tttatcgact ttagtgaaaa attaaaccag
    16021 ccttatcagg aaatccgaaa caactaccca agacaagcag aacttccttt tgactcagat
    16081 cgaaaattaa tgtctactgg acacacaatt gataacaaaa attacttgtt tgttaaaggc
    16141 ggaccagata tcgtcttcca acgcagtaaa aaagtattgc taaatggtga agtcgttccg
    16201 atgacggatg aattgatgaa aaaattccaa gagcaaaatg aagctttttc aacacgcgca
    16261 ttacgtgtac tagcttttgc ttaccgtcca cttgataatt ttgatttatc atttgaagat
    16321 gaagacgatt tgatccttgt tggtttgctt gctatgatcg atcctccacg tgctgaagtg
    16381 actcaggcgg taacagaagc aagaagtgca ggaatcaaaa caatcatgat tactggtgac
    16441 cacaaaacaa cagctgttgc tatcgcaaaa caaatcggga tttttgaaga aggaaacctg
    16501 gctttgaccg ggacggaact agatgaattg acagaagatc aactaaacga agttttagaa
    16561 aaagtcactg tttatgcacg tgtttcacct gagaataaaa ttcgtatcgt tcgtgcttgg
    16621 caaaataaag gtcatatctc agctatgaca ggtgatggtg taaatgacgc accagcattg
    16681 aaacaagcag acatcggaat tgctatggga acgggtacag atgtggcaaa agatgcagca
    16741 gcgatggtat tgacggatga taactttgct tctattgtca gcgcagtaga agtaggacgt
    16801 aatgtgtttg ataatatcaa gaaagctatt tcttatctat ttgcaggaaa tttaggtgcg
    16861 atcattgcga tcatctttgc cttagttgct gactggtcca atccatttac agcattacaa
    16921 ctgttgttca tcaatttagt caatgattca ctgccagcaa ttgcattagg tacagaaaaa
    16981 gctgaacctg ctacgatgaa ccgcccgcca agagatccaa attcaggaat ctttacggac
    17041 aaaacattga tttctgtaac gtatcgtggt gtgctgattg ggattgctgt tatctttgct
    17101 caatggcttg gcatgcagca ttcacctgaa ttcggtgtag ccatgtcatt ttcaacattg
    17161 atttggtgtc ggacattgca aacattccca gcacgttcaa acacacaaac agctatccaa
    17221 gcagggttct tctctaacag aagtgtctta ctagctgtag ttgtatgtag cgcgctttac
    17281 tgcttaacaa tgatcccagg actgaaagaa gtcttctcta tcccatcagc atttggattg
    17341 acagaagtct ttacatgtat gggaatcgca cttgtgacaa ttgttttgat ggaaatcact
    17401 aaattgatca ttgtacgagt acaaggaaat aaataaaacg aatcaacgag gttgtgagcc
    17461 tgccgtttaa ttctgagtca caaggtgcaa tttcaacaaa cagcttctca tgtttgttga
    17521 atattgtgac ttgtgaccga agagttggca ggagaacacc gtttaaggaa gaagttgtaa
    17581 aatcagcatt ttgagctaat actgagggtc atctgattgg acactgttta ttcggaaaga
    17641 gggactttga cacgactttg gtcacagtcc ctttttttat ttatgataga cggaaagcca
    17701 atcattttat tattcatcaa aagagataga atagataaaa gaggagaatg atttattccg
    17761 aaaagtgaaa acatataaca aaaaattaga ggaaatcaaa tgaatgaaaa agaatgggat
    17821 gaatttgctg aagaatatta tgaaatccag caagaatcgc aagtaactat tgctgaagat
    17881 gtaaaaaatt atctgaaaac ggagaaagtc ctgcctgctg aaacagcagc agacgttgct
    17941 ggaggatctg gcagatttct ttccttagca aaagaaatta atcgctatga tttgatcgat
    18001 ttttcttcag gaatgctaga aaatgcaaaa aaagaagcag aaaaaaatga gttgccaaat
    18061 gtttccttta tcaaacagtc gttagaagaa tttatccaat caaatgagac atatgaaatg
    18121 gtttttacag cagcaaatcc agcattggta catcttattc aattagaaaa attgatgaaa
    18181 aagtcaagca aatggtgcgt gataatcaga gtagtggaat caatcgatga tgttttttat
    18241 cctatcgaaa agcaactagg aatgatagaa gaagatccta atacatcgcc agttgtaatg
    18301 gatcaatttg aaacatactt aattgatgaa ggattcaaag tgaagaaaaa agattttact
    18361 tattttacac aggaatcaat tactgaagaa ttgatgaagc tatactatga cgcgtacgca
    18421 aaagatcctg ttgtgaccag gtacattcgc aaactattca gtgaaaaacg agaaatcctt
    18481 agtacgacta agctgaccta tagactgctc ctttggtccg cagataaaaa aagaaccttt
    18541 cacgactcgt gaagggttct ttttatgatt ttattatatt ttgtagtaac gaatatcatt
    18601 ttcgatcttt gtaatcgaaa aaggtacatc tgaagtatat tctgcacatt ctccgtgttc
    18661 aggaagcgtc tcactgaaaa tcgtttcata ttcgtcaaca gtgatccgtg ttcgagaatc
    18721 tagcatctct tgatgagatt gtgcgaagag atattcttga tagttttctt ccagataacc
    18781 tgtaaaaaat tcacttactg caccagaacc gtagctgaat agaccgatgc gatctcctgg
    18841 ctgtagtgat ttcgaatttt ccagtagaga agttagcccc aggtataatg aaccagtgta
    18901 aagattaccg attcgtcggc tgtaacggat gctttcttca tagcgagcca taagacgttc
    18961 ctgattttct tcgtctgttt ggtctaatac gctttgcaat gccttttttc ccatcttagt
    19021 atacggaata tggaaagcaa tcgcctgata atcttcgagt cctcgacccg acaattcttt
    19081 atgtcgattc caaacttttt ggaatgattc gatatacgta gaattagata aaggaccatc
    19141 aacaacagga aattcgctat aatctggacg ccagaaatca tagatatctt ctgtcagaaa
    19201 tacgctgtcg tcttcaatcg ataaaatacg cgggttttga gtgatcatca tcgcaacagc
    19261 accgacacct tgcgtcactt caccaccgct tgccaagccg taacgagcaa tatcacttgc
    19321 tatgactagt acttttcgtt ctggatgatt tttgacatat tctttcgcca tgtgcaaagc
    19381 tgcggtgcca ccgtagcaag cctcttttac ttcaaaagaa cgagcaaaag attggatttt
    19441 cagtaaatgg tggataatta ccgcactcgc ttttgaatga tcaatcccgg attctgttcc
    19501 gacgatgacc atgtcgatta gctcacggtc tttttctgtt acgattttgc tggcagcatt
    19561 tgctcctagt gtaatgatgt cttcatttgc acgattgact gccatttggt cttgaccaat
    19621 ccctatatgg tattttgcag gatcatcccc acggctttct gccaactctg tcatatctaa
    19681 atataaatta ggaataaaaa aggaaagacg atcaatccct attttcattt caacacctct
    19741 ttacttatga taaaaaactt actttactaa ggtatcataa aaagattaaa agaaatataa
    19801 aaaagagaat atttaaggat tgttaaaatt taatcttaga aaaaaataac tggaacaaga
    19861 gctatttgtt tttacagcaa agaatggtat atttttgtag gaggtggctt acttgaaaga
    19921 agtcgttatg atagatgctg caagaacgcc gataggaaag tatcgcggaa gtttaagtcc
    19981 atttactgca gttgaattag gcacacttgt gactaaagga ttattagata aaacaaaact
    20041 gaaaaaagat aaaatcgatc aagtaatatt tggaaatgtc ctgcaagctg gtaatggtca
    20101 aaatgttgcc agacagattg ctttgaacag cggtctccct gtagatgtcc cagcaatgac
    20161 gatcaatgaa gtttgcggat ctggtatgaa agcagtgatc ttagcacgcc agctgatcca
    20221 attaggtgaa gcagaacttg tgatagccgg cggaacagag agtatgtctc aagcacctat
    20281 gctgaaacag tatcagtcag aaacaaatga atatggtgaa ccaatttcca gtatggtcaa
    20341 cgacggattg actgacgcat tttcaaatgc acatatggga ttaaccgcag agaatgttgc
    20401 aacacaattt tctgtgagca gagaagagca ggatcgctat gccttgtcgt cccagttgaa
    20461 agcagcacat gctgtcgaag ccggtgtatt ttctgaggag atcatcccag tcaagatttc
    20521 tgatgaagac gtgttatctg aggatgaagc agttcgtgga aatagtacat tggaaaaact
    20581 gggcacgtta cgtacagtat tctcagaaga aggaactgta acagcaggaa atgcttcccc
    20641 gttgaatgac ggtgcctctg tggtgatcct tgcatccaaa gaatacgcag aaaataataa
    20701 tctgccttat ttagcaacca tcaaagaagt agcggaggtc ggtattgacc caagtatcat
    20761 gggaatcgct ccaatcaaag ccattcaaaa attgacagat agatcaggaa tgaatttatc
    20821 aacaatcgat ctttttgaga tcaatgaagc atttgcagct tcttctatcg tagttagcca
    20881 agaactgcag ttagatgaag aaaaggtcaa tatatatgga ggagcaatcg cattaggcca
    20941 tccaattggt gcaagcggtg cacgtatctt gactacatta gcttacggat tgcttcgtga
    21001 acagaagaga tacggtattg cttcattatg tattggtgga ggtttaggct tggcagtctt
    21061 gttagaagcg aatatggagc aaacacataa ggatgtgcaa aaaaaaaagt tttatcagct
    21121 tacgccatct gaacggcgca gtcaattaat agaaaaaaat gtattgacac aagaaactgc
    21181 gttgattttt caggaacaaa cactttctga agagctctcc gatcacatga tcgaaaacca
    21241 agtgagtgaa gtggaaatcc caatggggat cgcgcagaat tttcaaatca atggcaagaa
    21301 aaaatggatt ccgatggcaa cagaggaacc atctgtcatt gcagctgcaa gtaatggtgc
    21361 aaaaatctgt ggaaatatct gcgcagaaac acctcagcgg ctgatgcgag ggcaaatcgt
    21421 tctatcagga aaatcggagt atcaagcagt gatcaatgca gttaatcatc gaaaagaaga
    21481 gctgattctt tgtgcaaatg aaagttatcc ttcaatcgtg aaacgcgggg gcggtgttca
    21541 agatatctct actcgggaat tcatggggag tttccatgca tacttatcta ttgatttttt
    21601 agtggatgta aaagatgcaa tgggcgctaa catgatcaac tcgattcttg agagtgtggc
    21661 aaacaagtta cgggagtggt tccctgaaga agagattcta ttcagtattt taagtaattt
    21721 tgctacagaa tcattggctt ctgcctgttg tgaaatccca ttcgaacgct tagggagaaa
    21781 caaagaaatc ggtgaacaaa ttgccaaaaa aatccaacag gcaggggaat atgcgaagct
    21841 tgacccttac cgtgcagcaa cgcacaacaa agggatcatg aatggtatag aagctgtagt
    21901 ggcagctaca ggaaatgata cacgtgcggt tagcgcttcg atccacgcct acgcggcaag
    21961 aaatggatta taccaaggat taacagactg gcagatcaaa ggggataaac tagttggaaa
    22021 actaacggtg cctttggctg ttgccacagt aggcggagct tccaatatcc tgccaaaagc
    22081 aaaagcatct ttagctatgt tagatattga ttcagccaag gaactagcac aagtaattgc
    22141 tgcagtaggg ttagctcaaa acctggctgc tttgcgtgca ttagttacag aaggaatcca
    22201 aaaaggccac atgggacttc aagctcgttc attagcgatc tcaattgggg ctattggtga
    22261 ggaaatcgag caagttgcga aaaaattacg tgaagcagaa aagatgaacc agcagacagc
    22321 tatacaaata ttggaaaaaa tccgggaaaa ataaaaaagc aatatcttta gaagaataaa
    22381 gcaagattta cagttatttt atttactgca gatcttgctt ttttctctat cagaaaatat
    22441 gtttattatt agaatttttt atagttaagg ttaggcatct taagaaatca ggcaactcca
    22501 agatatcttc aggtagaaga gaagtcgcct aacattgtag gatcataggt gatttgttgg
    22561 acaggtcaag ctgatatttg agcctgatgt tagaaggaat ttctttttac ttgctgtaga
    22621 aattattata tgactaaaaa ggctgggatt ttaaatccca gccttttatg acaaatagaa
    22681 tttttatcga tcagtaatcg ctgtcgctgc aaattgttcg atcaaaggaa tcaaagtcaa
    22741 tttgactttg tatttccgtt cgagtgcttt ttcgataacg aactcatttt cagtagtcat
    22801 agaaatagtt gctaatttac gaggttcatc agcatttttt tcattaataa ctacttcatg
    22861 ttcattttgt tctgtgtaaa atttaggata ctcagcaacg gcttttgaaa aatcagcaaa
    22921 acttaaagcg gcattcgtat cagttgagcg tgtattttca gttgtgtccg cttttggttt
    22981 ttccgttttt tcttctggca cactgactgt ttcttctgta actggtgtcg caacagcttg
    23041 cgcagttggt tcatcgtttt tcaatcgttg atcattccag taagacacga tttcaataag
    23101 aagattgtca cggaatcgtt cgaaaatccc gttttctcct gaacgaattc tctttaatac
    23161 agtattgaag ttgtcatcga ttggcacgtt gatccgtgta tcttcatttg ttttcccagc
    23221 taatccgatc gttaagattt gacggttttt gggatcaagc atgacttgta acggcaaacc
    23281 ataacgtcgc aagctctctt cttctagaga acggaataat tgtcctctta caccatccaa
    23341 tgaaggacgg aattgattta ataatttttg tttctgtttt ttcttcatat gttctctcct
    23401 tcgctcatac cctttcgatt ataagaaaaa aacagccaaa tgaaaaggag taatgcaaaa
    23461 aaacttgcgt atacgcaaat tacaacagaa aaatttgcgt attttcccgt tttttgaaag
    23521 aaaaataaaa aatggaacgg attatgtata tatacataat ccgttccatt ctttctattt
    23581 tttcggtatc aaggcaaaaa caggtagttc aggtgaataa atgacttcat gttcgtgcca
    23641 gggtttgacc attagcgaat gatcgaaccg ttttttcagt tcttcgatga tttgatcatg
    23701 tgtccagttt cttgcaggaa aatgttggat tttctctgca tcgatcaaaa agacaaaatc
    23761 ggaatgaaaa gtctgggtaa cttcttccga gagagaattc aagcgttcga ttggatccat
    23821 aaaatcacct ttcgacttaa aattgggtag tatctgggtc ttttgctttg ccgactacac
    23881 catctaactg atcgatttgt ttcatttctt cttctgttaa ttcaaaatca aataattcag
    23941 tattttcttt gattctgctt ggtgtcactg acttaggaag aggaaggaat tcgtgttgca
    24001 gcgaccaacg caaagcaact tgtgcaatcg tcttgtcatg tgcttcagcg atttgtttca
    24061 tttcaggcac atcgaagatt ttaccagtgc ctaatggact atatgcttcg aggatcatat
    24121 catgtttttt tgcatactca actacagttg tctgtaattc gcctggtgca aggaaaactt
    24181 gattgaccat cggcataatt tttgctgttt ttgctagtgt atctagatgg tggggtaaga
    24241 aattgctcac accgattgct ttgattttac ctgcttcata cagttcttca aatgctcgcc
    24301 atgtatctgc atttgcttgt tcccaattat cacgaaaagc aacagggttt ggccagtgga
    24361 tcaaaaacag atctaaataa tctgtttgga gcttcttcaa tgattcttca aaagaagaca
    24421 tcacaagttc atagctgtgg tttgcattcc ataattttgt tgtcaagaat atctcttctc
    24481 taggaattcc actttcctta atcgcttggc cgacgctttc ttcattcttg tatccttggg
    24541 cagtatcgat atggcgataa cctgcagcca gcgcttcttt aacagaggaa acagcgacat
    24601 ccccatcagg tgtttgccat gtgccgaatc ctactaccgg gatttcgtaa ccatttgata
    24661 gacgataagt gcttgttaat gaattcatac tttcagctcc ttttttattc gttcaactat
    24721 aagtgtagcg catttttcga aaaaaagaat ccattttgtt tctactcttg aaatttttgt
    24781 ttaaaagaaa atgattttga ttctggtatt tttgattttt tttccgtaaa ctaagacaga
    24841 agggaatgag aaaatggata tctatttaaa aaaagcaatt ctgcatatta ttgacagaga
    24901 aactggttct ccagtctttt cacaaaaaga gctggatctg acaaaagaat atattcgtga
    24961 ttttcttcaa aagaagatcc aaaaaatctc ttctgctcaa acaaaaactg gacaactagc
    25021 agaagaaagc atgatcgttg aatcacttaa aatcgctcaa gaaaattttg tggaagcaag
    25081 tgaagcaatc gttcagcggt ggttcgatat ctaccaagaa agtgaagaag cacctagtgc
    25141 agatgtattt gttgtcttgt atgaattaga tacagtgatg tacttatctt tattgaaagt
    25201 caattatcgt gaggcttaca ctcactttgt tgaagcagac gaagcaggga tcgacaaccg
    25261 cttgattttg aatcgagcaa ttctaggggc gaaaacacaa aaagcagatg aagcattcgc
    25321 tgtgaatttg actgattgga cctacgaatt aattgaaaaa aaatatgagt tttctggcaa
    25381 aaaagagctt tatttttctg gaagagtgat cgaaagtgtt cctgcacctt ctttagaaga
    25441 aaatgtaaaa gtgatccaaa aagtagccaa gcatcttgga aaaaaatttg agacagaaga
    25501 atttgatatc atggctgatt tgaaagaagc tgtctatgat acgatagaag aaaaaggtcg
    25561 gttggatcat gagatgattg cggaaaaagt cttcaaggaa aacatcacgg caaaaatggc
    25621 ttttaaagaa gaagtacaag agcaaggatt tgtcccagaa gcacctcctg taaaagaagt
    25681 acaagaaatt tctgagaaaa aatttggaaa acaaaaattc aagctatcaa acgggatcga
    25741 actgatcgta ccagtagatg tatatcgcaa cccagatttg attgaatttg tgaataatcc
    25801 ggatggtacg atatccgtga tgatcaaaaa tgtggatgaa gtattgaatc gtttataaaa
    25861 atgactagaa tattaggtgt tcaagtacca gtgatcagtt aaatgaattg tgtcaagaga
    25921 aggatcggaa aagacgaata taacaaaaaa agagcgtgag acaaaagtaa agaacacttt
    25981 tgtctcacgc tctaaacacg tataaacggc ggaagcagaa gcaactcctt cttatttctt
    26041 ggagttaaac gcttctgtcc cagcctcttt ttatctaata aaattttaag accatttact
    26101 aattatcgat tttttctgcc gcatttttag gcacttcaga agcctttatt tcttcccagc
    26161 ttaatacacc tttacgagga ttgactttga gtttaagata cgcattcatc tttaatggat
    26221 gttctctttc ttcgcgaagc gtcacctgtt ttttttcacc atctttatta taagccgctt
    26281 gcttgtaggt ataagtcgtg aatttctctc cgttatctgc ttgggtagct gacatttcgc
    26341 cattcgtcgt gatttttgta taataagctt cgccgccgta aaaataatga taagctgcaa
    26401 aacttccgcc gagaaatatg cctaaaacga caagtacgcc aattaatttt ttcatgtact
    26461 tcacctcttt ccttattatt aacgaaatag aagatttcgt ctattgaaag ttgttggcaa
    26521 cagctgaatt ttaaactttt cctcattttg ttcttattgc ttcaaaagaa agttaaggac
    26581 tatcttgaag tttttctcaa aaaacacatt tttttattta taaaaggtac ttttttcgcg
    26641 tataagacag acgagtgctc ttagttgact ttgaccaata ttgacgtata ataagcttag
    26701 ttcgaatctt acaaaaagta agtcggacgt attctttttg atttagtcaa aaaaagacta
    26761 taataaaaag gtgagagctg aaatttttca gtgatctata ttatttagga ggtttgtaaa
    26821 ttatggcaaa agaacattat gacagaagta aaccacacgt taacattggt acgattggac
    26881 acgttgacca tgggaaaact actttaactg ctgcgatcac tacagtatta ggcaaaaaag
    26941 gcctagcaaa tcctcaagac tatgctagta ttgatgcagc tccagaagaa cgtgaacgtg
    27001 ggattacgat caataccgca cacgtagaat atgaaacaga aaaacgccac tacgcgcata
    27061 ttgatgcacc aggacacgcg gactatgtga aaaacatgat tacaggggca gcacaaatgg
    27121 atggtgcaat cttagttgtt tctgcaactg acggtccgat gcctcaaaca cgtgaacaca
    27181 ttttattgtc acgccaagtt ggtgtaaaat acctgattgt tttcttgaac aaagttgatt
    27241 tagtcgatga tgaagaattg atcgatttgg tagaaatgga agttcgcgag ttattgagcg
    27301 aatatggttt cccaggcgat gacactcctg tgatcaaagg ttccgcatta aaagcattgc
    27361 aaggcgatcc agatgctgaa gctgctatta tggaattgat ggatacagta gatgaatata
    27421 tcccaacacc agaacgtgat acagataaac cattactatt gccagtggaa gacgtcttct
    27481 caattacagg tcgaggaact gttgcctcag gtcgtattga tcgtggtgct gttcgtgtcg
    27541 gtgatgaggt agagatcgta gggatcaaac ctgaaacaca aaaagcagtt gtaacaggtg
    27601 tagaaatgtt ccgtaaaacg ttagattacg gggaagctgg ggataacgta ggcgtgttgt
    27661 tacgggggat ccaacgtgac gatatcgaac gtggacaagt acttgctaaa ccaggttcca
    27721 ttactccaca tacaaaattc aaagcagaag tgtacgtgtt gacaaaagaa gaaggtggac
    27781 gtcatactcc attcttcaac aactatcgtc cacagttcta cttccgcaca actgatgtta
    27841 caggaacaat cacattgcca gaagatacag aaatggtcat gcctggtgac aacgtgacga
    27901 ttgatgttga cttgatccat ccaatcgctg ttgaaaacgg aacgacattc tcaattcgtg
    27961 aaggcggacg gacagtaggt tcaggtatcg ttacagagat cgaagcataa gaaacgcgac
    28021 tcgaatattt tggtaatgaa aaatgtttaa aataaaagag cggtccaaac aggatttctg
    28081 tttggaccgc tctttgttct tcaattgtat aagaagagat tgtagaagca tgaactttcg
    28141 ttttacttca gtctctttta ttcatcatga gagtgttcat ctatcggtat gcagttttta
    28201 atactttctt cgtatccatt ttttcaaacc acttattcta ccttgtgtct gctcaactgg
    28261 cgcattatca ataatcagca aagcaatcat aacatatgca atccaactat ctctagaata
    28321 tagagtataa cgtgagaccc agtttgtagc gtacttgctt ttatattctc ttaatccatg
    28381 gaaagaataa aaatgagaac caaactcgta aaccaagtat gcaatccttt cctgtaaaaa
    28441 actctttctg gaagttccga catttgaaag aggggccatc cctaaattga accattggat
    28501 atgttcttct ttcatatagg caaacaaatg caagaacaag aaatccatac tgccagaagg
    28561 tgctttttta gaatcatatc gcatcagatc aatcgttcct actttattgt tcgtgtaagt
    28621 aggcatgatc gttgcaaaag cgacaatttc ttcttgggta tttttgacaa ctgcaatagg
    28681 cgctctttgt agataatctt cagagaaaaa gcctaaagaa aacccttttt cctttcgtga
    28741 acccaaccaa ttatcagaga tatttttgaa agtactcatt tgctcagtag aaaatggtgg
    28801 ttgtaagaca tcaaatgtaa atccttctcg ttcgatccga ttcaagacag cacgagtgcc
    28861 cttcattttt ttccctgaag ttgtaaaact attcaggtct acataagctt cttcccccat
    28921 cttaatgaaa tcgtagccga attcatgcaa aatcataaca atctcttcgc ttgtttcgta
    28981 gaaaactggt aaatagcata gtcgatctgt ttcttcgata aaagcttcga ttgcttctgg
    29041 aaaatcttct ttcttaccag aaggatcacc cattacaata catttattat tgaagcaagc
    29101 gaattggaga agaacagttg gttcaccgtc tttttcatag gcaaacatcc gcttatcttt
    29161 taagaagatc aattgactat cggagtttcc tccataagtt gtaaggatct tcagggcctt
    29221 ttcttcatta aaggcttcgc caatctgttt cttttctcct tgaaggaaat gaacaaatag
    29281 aacgatcatg aaactaacag cgatgatggc caacaatccc gaaaaccaaa tcttttcaga
    29341 aggaaataag aaaaaggaaa taaaatggtg acgccgatga gggaaatccg gcagattgta
    29401 taccccaata acgatgtaaa gcaaggacag tgcaccaata atgattccat cgatcgtacg
    29461 ccactcccat gaatagatca attgttcccg aaataattcg tttttagaag caagaatgat
    29521 cagaagcaga atagacaaga aaaccaccgg tgtgaaacta aaatcactta ataaaacata
    29581 aagtaaagct agaacaatca agaagattgt aggcaaatat gctcgtttca cacgtgctgc
    29641 gatccctctg cccataatga ttaaaagaaa tcccaatagt atactaggaa attggataat
    29701 aaaatgaaat ttcaatgggt tcaaactatg aagccagcga aactctgtaa aagcttgcgg
    29761 gatagtggca gaaagtacta gcatgattcc agaaaagtat aataagacaa ccacgatttt
    29821 atgcgcaatt tctgttgcta attgtttagg gataccagaa taacgctgat caaaagtgga
    29881 accgatattt ttgaagaaaa agacgattcc aatcaaaaac ggaatgatgt agtagaacag
    29941 gcgatagagc aagatccaca caacgactat ttctcttggc acaccaatag cggacaaccc
    30001 gataatcatc attacatcga aactcccaat ttctcctgga atcatagaca cgattcctat
    30061 cactgaagca gcaatgaata atggaattgt ttgccacaga tcaatccgga tttccattaa
    30121 ataaccaaca gaaaggaaac taaacaggac accggtccat tccaacaatg aaactagcaa
    30181 tagctgtcct tgagttttaa gtgaggtacc accaaggaat cctttctttt tgaaagtagt
    30241 aaataaaaag acgacaggaa aatatagacc gccgccgatc aaccatatcc aatattgctt
    30301 caaaaaagga gcaactggcg tgaagactac aagtaaaaaa gaaagcagac tgtaaataga
    30361 aagtccagcc atcaaaaaca agaaaacttt cgataatgct tggatcacgt ttctgctctc
    30421 tttcttttgt ccatatagtt cagagcgaag ccccacacta acaaacccgc cgaaaccggc
    30481 aatattgttg atcgtattga tcagccagct tgtctcaaac aggtaacgag gattctgctt
    30541 ttgttcaagc atccgattca aaataatatc ataaccaacc ataggtaaca cagagataag
    30601 accaatcaat agcattagtc cgcttttcca tacaggtata gtggcaaacg tttctcctaa
    30661 ttgctggata gatagagttt taccgatgga catcaattca ccgacaataa tgacaatgac
    30721 agaaatcaaa aagattgttt tgaacagtcc taggtggttt ttcagccatt gtatggtatt
    30781 ttttaacaaa taaatcacct tctattccta atagttatgt ttcagaaaga aattgaagaa
    30841 cttctcgatt gaagcgttca ggatcttttc tagctaattc atgtccttgt tctttcacaa
    30901 gcacaaagga agcttttggt atagttttag ctatatacaa agaatgtttt agcttgatta
    30961 catctttttt tcccacgatg atcaaagtgg gggagttgat tttttttaaa tcattttctg
    31021 taagcccgat gtcatgcagc aaaagtttga taactaaaag atttttgcga agacttgggc
    31081 gaaataaaga gagtaaccat acccatgcat aatgaatatt actgatgact ctggcagaaa
    31141 aacgaacgcc tttaacaagc gtgtttccag aatttaaaat caatcgatga acttttttag
    31201 ggaagctgct ggcaaatacc agtgctagat ttgctccatc actaaatcca agaaaatctg
    31261 cctgatcgat tttttccagc aacatgatcg tattcagatc ctcggccatt aactgaaaat
    31321 tcaacataga tgcttcgttt gtcgaacgac catgtcctcg gctatctact agatacacgg
    31381 tatagtagcg ttcgagtaca gggacctgtt ctgaaaaaaa gcggccgctg ccgtcattgc
    31441 catgcagtaa aaagagaggg aagccttgac cgctcttttc atagtaaatt tcgctcccat
    31501 ctggcatttt tgcatatttc ttttcttttt tcacataatc acctactgtg taaagtataa
    31561 cgattatatc agtcattggg caattgtttt tactgaaaaa caacgatcat tttcgtaaga
    31621 tgtcaaaaaa tacaggaaaa ttcatttttt cttaaggcgt acacagaaat caaggaagaa
    31681 atagccaaga agataaagaa atagtaagat aaaaaaagat gtcaaaataa ctaggtgatg
    31741 aaatgaagcg aaaacgatta tctattatcc gtattctttt ttacatgatc attctgacgg
    31801 ttattggtgc ggtgttgttt ttatgaggaa gaacttatcg ttcggtaaaa cgagtggaaa
    31861 gctatcaaat agaaataaca acagctgcaa aaaattatca tatggaaaac tacgagaatt
    31921 tgatcaaggc gataatattg accgaatcaa aaggaaaagg gacagatctc atgcagagct
    31981 cggaaagtct gcatggagaa gctgagatca ttgataatcc agctgacagt attgatcaag
    32041 gtgtcaaata tttggcggaa atgatagtag aagcaaagaa acaaggatgc gatttatgga
    32101 cagctgtcca agcatataat tttgggaaag attatattgc ctatgtaaaa aatcatggcg
    32161 gagaaaacac agtagaatta gcagaagcgt attctaaaga tgtgctgagc ccacttttag
    32221 gaaatgagga agggaaacaa taccgatatt ggcggatcca gtccttgctt tacaatggcg
    32281 gctatctcta tcataatgga ggtaacatgt tttatcctga tattgtcaaa atgaatgaaa
    32341 aaataataga gacctatgaa aaagtcttta agtaaaatag caggaaatgt tcaatcatga
    32401 ataaaattaa atgaaagaag gagtgcgcaa atagtggaaa aaaggcaaaa aatggaaaat
    32461 caagaagtgg ggtacacaac caaagactgg atgttacggt ttgtgaaggg aatgtttatc
    32521 ggttcaggat ttatcttgcc aggagtcagc ggtggtgcat tagcagctgt ctttggcatg
    32581 tatgagcggc tgatttcttt tttagcccac cttacaaaaa atttcaaaga aaatgttttg
    32641 ttttttctgc ctgttggtct aggcggagtg acaggcatct ttctactttc ttttttagtc
    32701 agttttttat taggtgcgta tgaaacaacg atattatggt tttttgtcgg atgtatcgct
    32761 ggaactgttc ctgcgttatg gaaagaagca gggaaaaaag gaagagatac ttctgatgtg
    32821 atcatcatgg ttgttacttt tgttctggct tatttgtttt tattatgcgg cgctcaatta
    32881 tttgacgggc aagtcgatca gaattttgga acatggctga ttgccggcgg attgattggt
    32941 ttgggtatga tcgtcccagg attgagccct tctaattttt tggtgtatat gggattgtat
    33001 aaagcgatgg ctgacggatt taaagaagta cgacttgaag tgattgtgcc gatcggaatt
    33061 ggtgggattc tttgtgttct tggattgtca aaaatcatgg attacatttt ctcaaaggca
    33121 tatagcaagc tattccattt cattttaggt gtagtttttg cttcaacgat tatgatcatt
    33181 cctaccgatt acgcgggatt gggagttgct ggggtactag cttgtcctgt tctttttata
    33241 gccggtacag cactaggttg gtggatgagc cgtttggagg aacaatataa gtaaagatag
    33301 attgataata aaaacagcac acgggtgatt caaacaaaaa ggttggcatc ttttttgtaa
    33361 aatcattcgt gtgtttttct ataaatttta taaaaacaag ttgtttttaa tcttggaaca
    33421 cgctagactt aaacacgtga ttatttttga aagttggcgg aaaatggaga aaaagaaaat
    33481 gaatggactt acacagcaag aggtagttca gaaaatggct tctggccagc aaaatgacta
    33541 ccaggaagat gcatcaaaaa gtacaaaaca aatattcagc gataatatat tgacgttatt
    33601 caattttctg aactttggta ttgggatttg tctgttattt gtaggtgcgt attccaacat
    33661 ggcgtattta gcaattattg tcgtcaatat cgttattgga atttatcaag aaatacatgc
    33721 aagaaatctt gtacggaaat tatcgattgt ttcccaatca gaagtactag tgatccggga
    33781 cggtaaagaa caatcgattt ctactaaaga gctggtatta ggagatttgg taaaaatcgg
    33841 agcaggagaa cagataccag ccgatttaca ggttatatct ggacgggcag aagcaaatga
    33901 agctcttttg acaggcgaat ctgatttgat tgtcaaagaa actggagctg aattgctttc
    33961 tggaagcttt ttgacaagcg gttctgtcat ggctgaagtt atccgagtag gtgcagataa
    34021 ttatgctgtc cgcttgacta gcgaggcaaa gactcacaaa gctattcgtt ctgaacttgt
    34081 agattcgatt cgcaaagtat ccaaattcac tagtttcgtg attattcctt tggggatcat
    34141 actatttttg gaagcactgt tcatccgcga tgcttctatc aaaatttctg ttattgcatc
    34201 tgcagcagct ttgttaggca tgcttccaaa gggtttggta ttgctaataa gtattgcatt
    34261 aacgacaggg gtaaccaaac tggcaaaaaa acgaatcctt gttcaagaca tgtattcaat
    34321 tgaaacgctg gcccatgtcg atacattatg cttggataaa acagggacca ttactgaagg
    34381 gaaaatgagt atccagcggg tagaagcact acatccgctg tacgagaaag ccatcccaga
    34441 aattatgggg acgtatctgg cagaaagcag tgataacaac atcactatgc gggctatgag
    34501 agattatttt gagctttcta atcggtatga tgtgacaaac aaagtcgcat tttcttctga
    34561 tcgcaaatgg ggcgcgatgg aatttccaga actgggagtc gtgtacgtag gagcgcctga
    34621 acgtttggtg gaagaagatc ggcttccgga cagtctaaaa acagcccaag cgaatggcta
    34681 tcgcgtactt atgttgggga tcgctccaaa tcagcaattg aacgaagaaa aaccagcatt
    34741 tgttgagccg gttgctctgt ttgaaatcga tgatccaatc cgaaaaaacg ctcaagaaac
    34801 actagcttat cttcatgagg aaggtgtgga tctgaaagtg atttctggag acaatccttt
    34861 tactgtctcc aatatcgcta gacgtgcagg attaccgaat tatgatgcgt atgtcgatct
    34921 ttctcaaatt actgaagaaa tggaagtgcg agaagctgct catcgctata cggtttttgg
    34981 acgagtgagt ccgcagcaaa agaaattgct ggtaaatgaa ttgaaagaaa gcggcagaac
    35041 ggttgcaatg acaggcgacg gtgtgaatga tgttttggcg ttaagagaag cagattgcag
    35101 cattgctatg gcagaaggtg atggagcaac acgtcagatt gcgaatctgg tattgttgga
    35161 ctctgatttt actacattgc cagaagtcct gtttgaagga cgccgagtgg tcaacaatgt
    35221 gacgaaagtc tcaggcatct tttttatcaa aacgatttat tcatttattt tatcgattat
    35281 atgtgccgtt acagcaattg gatttccgtt tatccctatc caaatcacgc tgattgattt
    35341 agcgattgaa gggtatcctt ccttcttttt atcttttgaa caagataaaa gaaaaatcac
    35401 ttaccgttat ttgcctacag cacttattaa tgctttacca aatgccttgc ttgtagtagt
    35461 gaatatcatt gcggtgtatc tacttggaaa aacattcgca tggggaaatg ctgaaactac
    35521 tactttgatg tattacttgc tgattgggat cagttgcatg gcagttgtaa aagcttgtta
    35581 tcccttcaac ccattgcgca tcttcctagc agtaacgacg atcgtaggga tatatgtagc
    35641 tgcaatgctg ttccatggaa ttttggaagt aaacttaggg ttgggagaga gcgtaggata
    35701 cttctttgta ttcatgctcg taaatattgt tcttcgagta ttgtactgga aggctgatat
    35761 tcaaaatcag ttactgaaaa gagtagcaaa ttgatgctta atgagataga aatgtgttat
    35821 acttgaaaaa gcaatgaaat atgatacaat caaacatgta taattgtgtc ctttaaaatc
    35881 gcactgattt cagttagtgc gattttttac cggttattct cctgaaatat cttctgttaa
    35941 acccaaaaga tatcaataga gcagggggtg aaaaaatggc tcaacggatt cctcaagagg
    36001 ttatcgaaac agtacgcagt caaacgaata tcgttgaggt gattggacaa tatgtccagt
    36061 tgaaaaagtc tggtaaaaat tacttggggc tgtgtccttt tcatgaagaa cgtacaccgt
    36121 ctttttctgt tgcagaagac aagcagattt ttcattgctt tggttgtggt aaaggcggaa
    36181 acgtgtttac ttttcttcaa gaactagaag gtctaagttt tccagaagca gtggtaaaag
    36241 tggcagactt cgaacagata ccgttagaag atcaatggcg tcagcgtact atagctgtcc
    36301 aaaatcctga atctgctacg gggaaactga ttgctgctca tgaaaaagca gcggaaatct
    36361 atcatcacat gctattgcat acaaaagctg gacagccagc tttagaatat ttgcaaagtc
    36421 gtgggttgtc tttagaatta attgaagaat tcaacatagg ttttgcacct aatgagcgtt
    36481 cttttcttca gcaagtattc aagaatgaat caatttcaaa tgaattgtta gaacgctctg
    36541 gattgtttgt cacgcatgat gatggccgta tgtctgatcg tttttatcaa agagtgatgt
    36601 ttccacttcg taattctcaa ggccagacga tcggtttttc aggacgctgg cttgcacctg
    36661 aaaaagggca ggaaaaagat cagcccaaat acttgaatag tccagaaaca gaactgttca
    36721 ataaaagaca agttttattt aatcttgata aagcaagaag cgatatccgg aaaaacggag
    36781 aaattttgtt gttcgaaggg tttatggatg tgattgctgc atggcaggct ggtatcaaaa
    36841 ctggattagc ttctatgggg acaagtctaa cagctcaaca gatccaacaa atggaaaagc
    36901 tgacgaaaga attggtcttt tgctatgacg gagacaacgc aggttttgaa gcaaccaatc
    36961 gagggattga attgcttcgg caaaacagtc gattagcact ttctgtcgta gtcgttccag
    37021 aaaagcttga tcctgatgaa tatctccgta agtatggaga agcatctttc caagaattag
    37081 tggctcatgg gcgcgaaaca gtctttactt ttaaatcacg ttatttaaaa caagggaaaa
    37141 atttagataa tgaaaaagac aagatcgaat acctcgaaga attactagtt gaacttagcc
    37201 gagttgtttc accaatcgaa caagatatgt atctatctca actgtcaaca gagtttcaga
    37261 tcggcagaga gacgatacaa aaacaactgc gcgatcttcg aaggacaaat cagcaaaatc
    37321 gtcaagaacc tcaggaaagt caacacactc aggttacgag acaagaaact gcacggaaaa
    37381 agagaccttt gacgcaagta gaaaaggcag agcagattct attatatcgt gcatttaaag
    37441 aagtttctgt ccgtaatatt ttaaaagaac gagaatttca gtttattcat gatgcatatg
    37501 cagaagttta ttttttattc gatgcatatg tctcacaaca ttatgaattc aaccttgcag
    37561 agtttttaga ctttttgcaa gatgaaaatt taaggcggtt ggtggtggaa atcgaatatt
    37621 taccggtggc agaagaaagt tcgccacgag aaatccaaga cttgctagat gtgatcagca
    37681 aatctggctt agctgatgaa ataacattaa aaaaacaaat gcagcaagaa gccagacgaa
    37741 ctggaaacaa acagcttgag cttgaattga cgattgaaat catcaattta acgaaacagt
    37801 taaaacaagc caaatagcta ctcaaggggg gccttctttt atggcaaatg gaacagataa
    37861 aaaaacgtat gaagcagcag tagcagcttt catcaaagaa aacaaaccca aacgacaagt
    37921 tgtatatgat gatttatcca atcagcttgc tacaccattc actttgaatg cagatgaaat
    37981 ggacaaattg atccaaaaga ttgaagacgc aggtatcagt gtggtggatg aaaatggtga
    38041 tccatcaatt cacagcttga agagtgctga gaaaaaagct gaacaagcaa aaacagaaga
    38101 tctttctgcg ccaaccggtg taaaaatcaa tgacccggtt cgtatgtatc tgaaagaaat
    38161 tggccgtgtc tcccttttaa ctgcggaaga agaagtagcg ttagcattga aaatcgaaga
    38221 aggcgaccaa gaagcgaaac agcgtctggc agaagcaaac cttcgtttag tagtaagtat
    38281 cgctaaacgt tatgtaggac gaggcatgca gttccttgac ttgatccaag aaggaaacat
    38341 gggactgatg aaggcagttg aaaaatttga ctaccgcaaa ggatttaagt tttcaaccta
    38401 tgctacatgg tggattcgtc aagccatcac tcgagcaatc gctgaccaag cacgtacgat
    38461 ccgtattcca gttcatatgg ttgaaacaat taataaattg atacgtatcc aacgtcaatt
    38521 gctgcaagac cttggaagag aacctacgcc agaagaaatc ggtgcggaaa tggatcttcc
    38581 aacagaaaaa gtccgagaaa tcttgaaaat cgcgcaagaa cctgtttccc ttgaaacgcc
    38641 aatcggtgaa gaagatgact ctcacttagg tgatttcata gaagaccagg aagcaacaag
    38701 tccagcagaa cacgcagctt atgagttact aaaagaacaa ttggaagatg tactagatac
    38761 attgactgat cgggaagaga atgtccttcg cttacgtttt ggtttagatg atggccggac
    38821 gagaacattg gaagaagtag ggaaagtatt tggtgttact cgggaacgta ttcgtcagat
    38881 cgaggctaaa gcattaagaa aattgcgcca tccttctcgt tcaaaacaat taaaagattt
    38941 cttagaataa gcgtggacta ttgaccagaa gagaaatcag taaaactgtt tggtttattt
    39001 taaaagaaaa aaagcttgag actacgcagt ctcaagcttt tttttctata ggaaggaaat
    39061 tcattcatta tttttaagta aatcctaaaa ataagctatt ggcgtgacgt atagaatatg
    39121 atagattaaa tggtagcgta aacctagtaa aggagccgat cgctaagtga tgaaaaaatg
    39181 tccaaattgc ggatcgaaaa aaatggagca gaatactatc tgtccagact gcggtcatca
    39241 aataactgca gaagatcagc aaataaaaga atcaattgaa gaaacaaata cagatgcagc
    39301 tatgcaggat aaatcaactg aagatgcagt ctttcctgat acagaattaa acgatccaat
    39361 cgaatggtcg gaattgaaag atttacctct agaatctgta atggaattat tcgaaaaagc
    39421 agaaccagaa gacgaagaac cacctgctca cgatcaagta actaatatag agaaaaatga
    39481 acagaagaaa gcaactgttc atgagacttc ggaagaatca ggaaagaatc aagaagaaac
    39541 gcttgaatca aaacaaaaaa gaagagtagc tgaactgaaa gaaatcgtcg ataatgagga
    39601 agaaaattcg atactatccg cttatatcaa agcacatcgt gaagatacaa aagaagagca
    39661 cgcgaaagag ctgctcaaaa tgatcagtga aaaaattgca caggaaaaca aagtagagcc
    39721 agaaaaggaa caagaaactg aaaaagactc tgatagagaa aacgccacag gtaaagaaac
    39781 agtaaaaata aaagacgtaa aaacggatat cacagaaaaa actgaagtat ttactgaaaa
    39841 acaattagaa aaggaaaaaa cgaataaact gccggaagca gagaaaaaag aaatactcga
    39901 aaacacagac aaaaagtcaa cagagcccga tgaaataaat agtgaatccg atgctgaaaa
    39961 tcaatctgta agcaaagagg gtactgatct tgaagcaaaa atagaaaaag aagagaacca
    40021 gcctaagctg tttgaagcag aagcgaaatc aataacaatc gtgccagata ctgaaaaaac
    40081 acatcaagaa tcaaacttag aaaaaacaga tccagataaa gcgcaaaaga aaaaatcaaa
    40141 aaaagtacct tatctcgttt tagcagcagt acttctactc ggtggaggaa gctgggctta
    40201 ttatgaccat catcaaaaag tagaagccga agtagcagca gaagcaaaaa gacagcaaca
    40261 aatggaagaa cttcatgaga aacttgctgc cttttataca gatgatcacc atcaatttat
    40321 tcgtgcagat atgattcatc aagatttatc aaaactaaaa aatgatttat ccagtcttaa
    40381 gaatgaaaaa ggatattcag agttagaaac aacttaccaa gatatccaat ctaagatccg
    40441 agatatccaa aaagtgaatg agtggttcat agcacctgcc atcgtcgatg atcatctagc
    40501 agatgacatc aagttgaaag cagataaaga gatccaagca atcgaaacgg ataacacaga
    40561 ttttggaaaa ttgattcaac aagcacaaac agaagctaaa aatcaatatg ctgaattgca
    40621 aacagctaaa gaaaaaacag ctatagtctt taaagacgga aaagtagtgg attcagcaac
    40681 acgcgaccaa tacaagacgg caaaagaagc agtagaaaaa gtgaaaaata cagatctatc
    40741 tgctcagttg aatgaacaat tgaaacaagt agataagatg ctcactgata aagagaaaaa
    40801 agaagaagag gaaaagaaaa aagcagaaga agcgaaaaaa gcagctgaag aacaagcaaa
    40861 acaagccgct caagcagcag ctgcagctca agccgctcaa caagctgcgg tcgcacaagc
    40921 agcacagcaa gaagcggcat cctcgacccc ttcctcttca aactcagcga atcagccaat
    40981 caaatctgcc agagcaagtg atattgccga tgcatctaat ccagcatgga cgtgggcacc
    41041 aggtgtccaa agcaaagtga ttgctacatg tatccaacgt ggatatatcg ttgaaggagg
    41101 ttacagatta gaaaaagcca gaatcgaaaa tggggaaggc tattataatc tatatgccac
    41161 ttcaacaaaa tctgcattga tgaaaggcat tggagaaagt gctttgccat tttacatcgt
    41221 aaccatcaac tgtaaaactg gatggttcgg aggaaatggg agcaattaat tttaggcaaa
    41281 tgaaagaggc tgtgagcctg ccgtttaaca ccgtttattc gaaaaagggg agtatgacac
    41341 aactgttgtc atactccttt tttcaccttt ccaaaccaag gctcagctat tcaagtagat
    41401 aacattatgt tatgatagca aagaaatgta ttaagaaaac ctttcactat agagggagaa
    41461 aaaaatgaac gatttattag caactatatt tacaggtatt attattgatg aaaatgaaaa
    41521 aaactacttt gtccaaaaaa acggacaaac ctttggctta agcaaatcag aaggtgaaca
    41581 caaaatcggt gaagcagttg aaggattcgg ttaccaaaat caaaaacatg aaaatcggat
    41641 cactacacaa attcctaaaa gccgtatcgg tcattacgct tttggaatcg ttactgctac
    41701 acgaaaagat ttaggtgcgt ttgtcgatat cggtcttcca gataaagact ttgtcgtatc
    41761 tcttgatgaa ttgccgacaa tgacagagct atggcctaaa aaaggggatc gcttgatgat
    41821 ttcccttaga gttgatgcaa aagaccgtat ttggggcagt ttagcagatg aaaaaatatt
    41881 caaatcttta agcaaatatg gaacagaaga aatgaaaaac aaagatgtga taggaacagc
    41941 ataccgcttg aaattaacag gtacgtacgt tttaacggaa gatttctatc ttgggtttat
    42001 ccatccttct gaacgatata atgaacctcg tctaggcgag cagataaaag gtcgagtgat
    42061 tggtgtccga ccagacggtg tactgaatct ttcattgaag ccaagagcat atgaagctat
    42121 atcagatgat gcacaaatga ttttaaccat tttagaacgt tctgcagatc agcaaatcaa
    42181 ctttacagat aaatcggatc cagaagaaat catgaaagct tttggtatca gcaaaggagc
    42241 atttaagcgc gcattaggta atcttttgaa acaaggattg attacacaag aaaacggtgt
    42301 gacaaaacta gtcaaaaaat ctaattgaga atcccttgca tgtttttctt aactagctta
    42361 taataatttt aattaacata gtgttatatc tttttttatt tgtaattatt ataaattgtt
    42421 ggggttgagt aaatggtcat gaatgctatt tcggcgatga aaaaaacaaa acagcagcta
    42481 catgaagcgg ggtttaagct gacaccgcaa agagaagcta ctctgcttgt gcttttggaa
    42541 aatgagaaag agcatttatc tgcagaagaa atcttctttt tagtgaaaaa aaagagtccg
    42601 gaaattggac ttgctactgt ttatcgaacc cttgaaatct tgacagaatt gaaaattgtc
    42661 gataaagtaa gttttaatga tggattagcc cgttatgatt tgagaaaaga aggcgccaaa
    42721 catttccatc atcatttact atgcttgaac tgcggcacga tcgaggaagt agaagaggat
    42781 cttttacttg aagtggagca agtagtagaa gaacgttatc attttttagt aaaagatcat
    42841 cggctaacgt tccatggaat ctgtcaggaa tgctatgaaa aagaaaaa
//
LOCUS       DAPBAF010000023        41544 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.023, whole genome shotgun sequence.
ACCESSION   DAPBAF010000023 DAPBAF010000000
VERSION     DAPBAF010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 41544)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41544)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41544
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.023"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(25..1521)
                     /gene="lysS"
                     /locus_tag="RD451_001431"
     CDS             complement(25..1521)
                     /gene="lysS"
                     /locus_tag="RD451_001431"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HDT7566699.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKAGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(1632..2636)
                     /gene="dusB"
                     /locus_tag="RD451_001432"
     CDS             complement(1632..2636)
                     /gene="dusB"
                     /locus_tag="RD451_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HDT7566700.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVACREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(2637..3524)
                     /gene="hslO"
                     /locus_tag="RD451_001433"
     CDS             complement(2637..3524)
                     /gene="hslO"
                     /locus_tag="RD451_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HDT7566701.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(3741..5852)
                     /gene="ftsH"
                     /locus_tag="RD451_001434"
     CDS             complement(3741..5852)
                     /gene="ftsH"
                     /locus_tag="RD451_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HDT7566702.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(5942..6487)
                     /gene="hpt"
                     /locus_tag="RD451_001435"
     CDS             complement(5942..6487)
                     /gene="hpt"
                     /locus_tag="RD451_001435"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HDT7566703.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6487..7932)
                     /gene="tilS"
                     /locus_tag="RD451_001436"
     CDS             complement(6487..7932)
                     /gene="tilS"
                     /locus_tag="RD451_001436"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HDT7566704.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8052..8522)
                     /locus_tag="RD451_001437"
     CDS             complement(8052..8522)
                     /locus_tag="RD451_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein S1"
                     /protein_id="HDT7566705.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(8568..8993)
                     /locus_tag="RD451_001438"
     CDS             complement(8568..8993)
                     /locus_tag="RD451_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HDT7566706.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9060..9329)
                     /locus_tag="RD451_001439"
     CDS             complement(9060..9329)
                     /locus_tag="RD451_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HDT7566707.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9340..10935)
                     /locus_tag="RD451_001440"
     CDS             complement(9340..10935)
                     /locus_tag="RD451_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HDT7566708.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(10950..14471)
                     /gene="mfd"
                     /locus_tag="RD451_001441"
     CDS             complement(10950..14471)
                     /gene="mfd"
                     /locus_tag="RD451_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HDT7566709.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14488..15048)
                     /locus_tag="RD451_001442"
     CDS             complement(14488..15048)
                     /locus_tag="RD451_001442"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HDT7566710.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15401..16375
                     /locus_tag="RD451_001443"
     CDS             15401..16375
                     /locus_tag="RD451_001443"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HDT7566711.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            16545..17945
                     /locus_tag="RD451_001444"
     CDS             16545..17945
                     /locus_tag="RD451_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase/peptidoglycan binding
                     protein"
                     /protein_id="HDT7566712.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18023..18745)
                     /locus_tag="RD451_001445"
     CDS             complement(18023..18745)
                     /locus_tag="RD451_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDT7566713.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(18824..19330)
                     /locus_tag="RD451_001446"
     CDS             complement(18824..19330)
                     /locus_tag="RD451_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HDT7566714.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSINHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19453..21252
                     /locus_tag="RD451_001447"
     CDS             19453..21252
                     /locus_tag="RD451_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HDT7566715.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            complement(21320..22894)
                     /locus_tag="RD451_001448"
     CDS             complement(21320..22894)
                     /locus_tag="RD451_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HDT7566716.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
     gene            complement(23149..23658)
                     /gene="mreD"
                     /locus_tag="RD451_001449"
     CDS             complement(23149..23658)
                     /gene="mreD"
                     /locus_tag="RD451_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HDT7566717.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            complement(23662..24516)
                     /gene="mreC"
                     /locus_tag="RD451_001450"
     CDS             complement(23662..24516)
                     /gene="mreC"
                     /locus_tag="RD451_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HDT7566718.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            complement(24671..25309)
                     /locus_tag="RD451_001451"
     CDS             complement(24671..25309)
                     /locus_tag="RD451_001451"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HDT7566719.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            complement(25310..25960)
                     /locus_tag="RD451_001452"
     CDS             complement(25310..25960)
                     /locus_tag="RD451_001452"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HDT7566720.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGRFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            complement(25973..26872)
                     /gene="rsgA"
                     /locus_tag="RD451_001453"
     CDS             complement(25973..26872)
                     /gene="rsgA"
                     /locus_tag="RD451_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HDT7566721.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            complement(27037..29106)
                     /gene="pknB"
                     /locus_tag="RD451_001454"
     CDS             complement(27037..29106)
                     /gene="pknB"
                     /locus_tag="RD451_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HDT7566722.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            complement(29103..29843)
                     /locus_tag="RD451_001455"
     CDS             complement(29103..29843)
                     /locus_tag="RD451_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HDT7566723.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            complement(29856..31214)
                     /gene="rsmB"
                     /locus_tag="RD451_001456"
     CDS             complement(29856..31214)
                     /gene="rsmB"
                     /locus_tag="RD451_001456"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HDT7566724.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKMLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            complement(31214..32152)
                     /locus_tag="RD451_001457"
     CDS             complement(31214..32152)
                     /locus_tag="RD451_001457"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HDT7566725.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKKAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            complement(32145..32636)
                     /gene="def"
                     /locus_tag="RD451_001458"
     CDS             complement(32145..32636)
                     /gene="def"
                     /locus_tag="RD451_001458"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HDT7566726.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            complement(32651..35059)
                     /gene="priA"
                     /locus_tag="RD451_001459"
     CDS             complement(32651..35059)
                     /gene="priA"
                     /locus_tag="RD451_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HDT7566727.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            complement(35312..35617)
                     /locus_tag="RD451_001460"
     CDS             complement(35312..35617)
                     /locus_tag="RD451_001460"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HDT7566728.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            complement(35622..36236)
                     /gene="gmk"
                     /locus_tag="RD451_001461"
     CDS             complement(35622..36236)
                     /gene="gmk"
                     /locus_tag="RD451_001461"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HDT7566729.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYVNKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEKRMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
     gene            complement(36723..37007)
                     /locus_tag="RD451_001462"
     CDS             complement(36723..37007)
                     /locus_tag="RD451_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566730.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            complement(37025..37915)
                     /locus_tag="RD451_001463"
     CDS             complement(37025..37915)
                     /locus_tag="RD451_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HDT7566731.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFVLDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            complement(37935..38153)
                     /locus_tag="RD451_001464"
     CDS             complement(37935..38153)
                     /locus_tag="RD451_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HDT7566732.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            complement(38123..39823)
                     /locus_tag="RD451_001465"
     CDS             complement(38123..39823)
                     /locus_tag="RD451_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HDT7566733.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            40090..40863
                     /locus_tag="RD451_001466"
     CDS             40090..40863
                     /locus_tag="RD451_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566734.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            complement(40944..41513)
                     /gene="thiT"
                     /locus_tag="RD451_001467"
     CDS             complement(40944..41513)
                     /gene="thiT"
                     /locus_tag="RD451_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HDT7566735.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
BASE COUNT        11336 a         9009 c         7530 g        13669 t
ORIGIN      
        1 attccttaga cagcttttat tcgattatct cattgttggg aatagcaaaa catcccgaat
       61 tgattgtgca tcagttagca acattactaa tctgtcgatc ccgatgccta gaccaccagt
      121 tggcggcata ccgtattcta aggcttccaa gaagtcttcg tctacaccgt gagcttcgtc
      181 atttcctagt tcacgttctt tttcttgcgc ttcgaatctt tctctttgat caattggatc
      241 gttcagttct gtaaaggcat tagcaaattc gcgccccact atgaatagtt cgaatcgatc
      301 tgtgaatcga ggatcttctg gatttttctt cgctaaaggc gaaacttcga ctggatgtcc
      361 gtatacaaac gtcggttgtg tcaatgtttc ttcaacaaat gtttcaaaga attcattgat
      421 aacatgtccg acacccatag cttcggttac ttctacattg tgtttttcgg ctaaagctaa
      481 tgcttcttcc aatgtcattt cttgccagaa gtctacacca gtttgttctt tgattgcatc
      541 taccatatgg atgcgtttaa agtcactttc taagtcgaca gcttgtccat catatgtgat
      601 ttttgctgtt cctagtactt tttcagctgc gttacggata ataccttctg tcagattcat
      661 tacatcattg aaatcagtat atgctgtgta tgcttctaac atcgtaaatt ctggattatg
      721 tgtagtatca attccttcat tacggaaaac gcggccgatt tcataaactt tttccattcc
      781 gccaacaatt agtcgtttta aatgaagttc tagcgcaata cgcaaatata aatcaatgtc
      841 cagtgcatta tgatgcgtga taaatgggcg tgcggcagct ccacctgcct cattgtgcaa
      901 tactggtgtt tctacttcaa tatagccatt gccatctaaa tagcgacgga tttcgctgat
      961 aatttggctt cgtttcataa atcggtcaaa gctttcgcga ttactgatta aatccaagta
     1021 gcgttgtctg tagcgttgtt caatattcgt taagccatgg tatttatctg gcagtggacg
     1081 aagtgctttt gacaaaatcg tgatttctga agctttgata gaaacttcgc ctgtgtctgt
     1141 tttcatgatt tgtccagtta caccaaagaa atctccaagg tctgcatgtt tgaatacttc
     1201 ataggcctca tcacctactt ggtcttttct tacataaatt tgaatttggc cttcacgatc
     1261 ttgtagatgc gcaaatccag ctttcccttt tcctcggcga gtcatcatac gaccagctac
     1321 actagcggtc aatcccattt ctgctagttc ttcttttgtt cttggatcaa atagttcatg
     1381 caattcttct gagttgtgcg tgcgttcaaa tcgttttcca aatggatcga ttccatcttc
     1441 acgcaattgt tccatttttt gacgacgtac aagcatttga tcatttaaat cttctacttg
     1501 atgttgttgt tcctgtgtca caaaagttcc tccattctca tgttaatctc tttcctataa
     1561 tgccaatgaa acacaaaaaa agcaagccga acttggaatt tcggcttgaa aattcacgaa
     1621 aaacttagaa atcacaacgt ttgtttcaat agtacttttt ccgctttttc tacaaattga
     1681 tccagcaggt cattgatttc ttgctgtttt tctgtctgat tgattgctac tttcactttc
     1741 gctgctcgag gaatcccttt taaataataa gccgcatgtg ttctgaattc tctacaagct
     1801 actttttctc ctttgagatc tgctaagcgt tgtaaatgaa gtttagctgt agcaattttt
     1861 tcggctggtg ttggttcagg aatcagttcc cctgtttcga gataatgctg tgtgcggtga
     1921 atcatccatg gattgcccag cgctgcacga ccaatcatca caccgtctgc accgacatag
     1981 tcaagcatcc attttgcatc ttctggcgtt ttgacatccc cgttccccat aaatggaatc
     2041 gtcaaatgtt ttttcacttc tttcaatact tcccagtccg cttttccttc atacatctga
     2101 acccgtgtac gtccatgcat agcgatggca cttgctccag ctgattgtgc tgctaatgca
     2161 ttttctacag caaagacgtg ctcttcatcc caaccaatac gcatcttgat tgttactggg
     2221 atatttactg ctgaagaaac agcttggacc atttcgtata ctttctcagg atctaaaagc
     2281 cattttgctc ctgcttctgc tttgattact ttatttactg gacagcccat attgatatct
     2341 attatatcgg cagctgtgtt ttcttcgaca aattgagcag cttcaactag actatcttta
     2401 tttccgccaa atatctgtaa acttaatgga tgttctgttt cttcaatgtg gagcatctct
     2461 aaagtttttt tgtttctgaa atgaatacct tggtcactga tcatttcaca tacgactaag
     2521 cccgcaccaa attctttgac agtgactcga aatgctgaat ttgttattcc agccatcggt
     2581 gcaacaacga cacgattagg gatttccaca ttgccaattt tccatgtgtg ttccacttaa
     2641 atccctccta aggcttcttt cttcaatcca tctaattctt cttcgctata cttgtatttg
     2701 ttattacaga aagaacaaac cgcttctgca ccgtgatctt cgtctatcat tgcttggatt
     2761 tcttctgcac ctaacgcgat aattgcttct gcaaattttt cttttgaaca gtcacatttg
     2821 aattgaacag gcattttttc caaaatgttc aattcttctg taccaagcaa tcctttcaat
     2881 atttcttctg gtgtctgtcc ttcatctaag agggtagaga ttcttggtgt cgtttttaat
     2941 tgttcttcga tcttgctgat tgtttcttca tcggcacctg gcatgatttg gatcatgaat
     3001 cctcccgccg tcttgatgct gtcgtcagta ttgaccaata cactcagtcc aacagctgaa
     3061 gggatttgtt ctgagatagc aagatagtaa gtaaaatctt cagcgatttc tccagaaaca
     3121 atcggcgttt gcccagaaaa aggttctttt aatcctaagt cttttgtgac agtaaacatt
     3181 ccttgtgttc caactgctcc ccgcacatcg attttacctt cactatttag aggaagactg
     3241 agatgcggat ttttgatgta acctttcaca tctccctttc catttgcatc tactacaatt
     3301 cctgttgctg gaccatcgcc ttggattcga acagttagtt tgtcttctcc tttgagcgtc
     3361 gcaccaagta gcagactacc gaccaatgtc cgtcccaaag cagctgagga ggtgtgccaa
     3421 gtatcatgac gtctttgtgc ctccgctacg gtatttgttg cttgaacggc gtatgctcgg
     3481 acgaatccgt cgtgagcaag tgccttaacc aaataatctt tcatttgtta tgtactcctt
     3541 tttccgtttt taaactcata gtgaatcata ctagcaacta ctgctttttt caactttgga
     3601 atgcttcttt taaaaataat tcagaatcat ctagaaaaca ggacatcacc ctatttacaa
     3661 cttaaataaa gaaatctccc gaaaaccggt ttttgttccg gttttcggga gtcatatcag
     3721 atcaattgac ctatattttt ttatttgtat tgatcgtctg aatgattatc ttctgattgt
     3781 tgagaatctg aatcatgttc tgctttattt tcctcattca gttcatgttt tgcttcttca
     3841 aaatcacgtt tttcttccgc ttgtttttca gcgtcttttt cttccaaagc acgttttgct
     3901 tcttcaaaag ttttcgcttc tttttcgctt ggataatcat ttgactcagt accttcaggc
     3961 atcacaccgt gttcaaacaa tgacttgatt gctttggcat ccaatgtttc gaattccaaa
     4021 agtttttcag caatcagttt atgctgtgca cgatgagctt cgatgatttc tcgagcttta
     4081 tcatgagctt ccatcaagat ttttcgtact tcttgatcaa tctcgaaagc gacttgttcc
     4141 gagtaagctt ttgtttgacc atagtcgcgg ccaacaaaca cttgatggtt tccttcatat
     4201 tgaacaggac ctaaacgatc actcattcca tattctgtta ccatgcttcg tgctagagct
     4261 gtcgcttgct caaagtcatt ggaagcacca gttgattgga cattgaagat gatttcttca
     4321 gctgtacgtc caccaagtaa gcctacgatt tgttcaaaca tatcttcttt cgtcatcaag
     4381 aactgatctt cttttggtaa agcgatcata tatccgccgg cgcgtccgcg agggatgatc
     4441 gttactttgt ggacgacccg agcgcgactc aatactaatc cgacaatcgt atgaccagct
     4501 tcgtgataag caaccatttc gcgttctttt ttgctgatta cgcgatcttt tttagctgga
     4561 cctgcaatca cgcgatcttc cgcttcatcg atatcagaag catcgatttt ctttttattt
     4621 cttctagcag ctactaacgc tgcttcattc aagacatttt ctaaatctgc tccggcaaaa
     4681 cctggtgtct gttgagccac aactttcaag tcaacgtcat ctgccatcgg tttattccgt
     4741 gcatggactc gcaagattgc ttcacgacct tttacatctg gacgtccaac taaaatctgg
     4801 cggtcaaaac ggcctggacg tagtaacgct gggtctagta catcagaacg gttggttgca
     4861 gcaatgacga ttactccttc atttccgtcg aagccatcca tttctacaag caattggttc
     4921 aatgtttgtt cgcgttcatc atgtccgccg cccataccgg caccacgttg acgacctacc
     4981 gcatcaattt catcaatgaa aatgatagct ggtgcgtttt tcttcgctgt ttcaaacaaa
     5041 tcacgaacac gacttgctcc aacaccgaca aacatttcta cgaaatcaga acccgagatc
     5101 gagtaaaacg gtactccagc ttctccggca acagcttttg ctaataaggt tttacctgtt
     5161 cctggaggtc cttctaaaag tacacctgcc gggatacggg cacctaattc aacaaatcgg
     5221 cgaggatctt tcagaaattc aacaacttca actagttctt gtttttcttc ttccgcaccc
     5281 gctacatcag aaaaacgtac gcgattagct tttttgtctg cttctttggc ttttgattta
     5341 ccaaagttca tgacacggcc gccaccgcca ccgccgccgc cttgttgtcc catcatcatg
     5401 taaaagaaaa agatgatgat tacgattggc aagaagctaa gcaataggga aacccatata
     5461 ccgctgcttg attcttcttt tactgttgta gcaactttgt tttcttttgc cagttctgtt
     5521 acttggctca atgttgtatc atttggcaaa atgattgttg tgaaatgggt agtagtcgta
     5581 tctgttgaac ctaagatagc taacccaccg ctgttagcga cggtctgctg ttctttgtat
     5641 tcaccagtga tcttatatac accatttgca ggctgcactt caaattcttt gatcttgcct
     5701 gcttgtagtt gttctgtgaa ttttgagtac tcgatatctg acgatcgctg gccgttatta
     5761 ccaaaaatga aataaacgac cattaccatc gctaagatta cgaggacata atacaaggca
     5821 tttttcatca tgccgttgtt ctttttgttc atagttgccc tccctaagcg tcaatttaat
     5881 ttaacagttt tttatcaatc ctgaccattc tattgtacca taatttaatt gagatacagc
     5941 attaatttga ttgataaaca ctaggtttca atacaccgat gtacggaagg ttacgatatg
     6001 cttctgcata atccaagcca taaccgacca caaattcatt tggtacgttg aagccaacat
     6061 aatctgcttc gatatttact actcttcctt caggtttgtc aagtagtgta acaattttga
     6121 ctgattttgc tttgcggtat ttgaaaagat ccactaaata agcaagtgtt cttccgctgt
     6181 caatgatatc ttcaacgatc aacagatcgc gaccttctac attcgtatct aagtctttga
     6241 cgatttttac ttcccctgac gagactgttg cattcccgta gcttgaaaca tccatgaaat
     6301 ccaattccaa atacgtatcg atagaacgaa cgatatctgc catgaatggt accgctcctt
     6361 ttaagacacc tactactagg ggattggtgt tttggtaaat ttctgttaac tctttgccta
     6421 gttctttgca acgaacttgt atctcttctt gtgagatcaa aattctctca atatcctttt
     6481 ccaacatcag gttctccttc caattgcttc tttttgatat ttgtaaagaa gtatgtagtg
     6541 tattttatca gtttcttcac gaatactcaa atatgaaaag gcaaaaggta tcaagctata
     6601 tatatttctt ttggcatctg taatgatcca agcatgctgc ctttgtgaat taggtacttt
     6661 ctgatcgata aaatatctag atactttttt tgtgagattc tctgttaatt taatgcggtc
     6721 tcctgctttt cttttttcga catacagttg cacatcagca ggaatccaaa tgtcatgaga
     6781 aaatagagac catgaatctg ttgctttgat gtcccctgca ttttcaggtt tgaccagacc
     6841 aatccattct gtttcattca aatatattcc ttgttctgga atcagcaaca agcgctggtc
     6901 ttctgtctgg ctagttgctt gtttttcttt tttagagagt acaacaaaat gatactctct
     6961 tttcagtatc caattattgc caatactgag ttgccattgg ctttttttct gttgccactg
     7021 gtctaaaatc gactccattt gttgttcttt caaaataatt cctgtttttg agaatgcttt
     7081 gtcgaaaaag gagtaaaaaa aatagtatcg ttcagcatct gtcatttctt caatcatttc
     7141 tgcagaaaat cgaaattgtt cctcccactg ttcgacttcc ttttcgatca actgtcccat
     7201 atatttttga atgacttggt ctgcccattg gatctgttgc gaaaattgct ggaaatgtct
     7261 caacgcctgt gtattttctt gtttcaattg aggaactacc aaatgacgaa gccgatttct
     7321 ctggatatct aacaattggt ttgtctgatc ctcaaagtaa acaagctgcg attccgctgc
     7381 ataagtatat aggtcttctt tgctaaaact cagcaacgga cgaatcagtc tgcccgtagc
     7441 aaatggttgt acttctttga ttccagaaaa agtatttaac tgtcccccac gaacgatttt
     7501 cattaacacc gtctcgattt gatcatctcc gtgatgagca gtcatcaacg tgtcatattg
     7561 tccttcttcc atcacgcgag tgaattcttg ataacgaaag ttacgagctt ctgtttctat
     7621 ggcggatttg gctggatctt cccaaatact tacatataaa gggagattct tctcttcaca
     7681 atatgagcga agataggcag cttcttctgc tgattcttct cttaattggt gattgatgtg
     7741 gacgatacct aaagaaaaac cgatttggcg ttgcacttgt aaaagtaaat ggagcaaaac
     7801 catcgaatca acaccacctg ataccgctgc taaaattctc gatccttgtt gccagaatcc
     7861 ttgttcattc ccgtgccgaa taaatgactg ctgtaatagc ggtgcttttt tcccgccttt
     7921 ttcaacgttc atcctttcca caccctttct tcctaaaaaa aagagagcgg gaaaacgtct
     7981 aaaacgacaa ttaacctgcc ctctgttgat actatgaccc aaatagtcgc actatcatta
     8041 tttgcggctt tttagctgcg acgtccgcca cggccaccgc gctttccttc tgtgtttcgc
     8101 ttcaatgaag ataagcggtc atcgctatct ttcaaaaatg aactcatcaa tgaatcgaag
     8161 tcttcttttt gagctgaagg ttgactgcga gaaaaagatt ttttctgtgc tggacgattt
     8221 cggttgtcac ggggatcttt ttgttgatat tttttaggac ggctttcttc tccagattca
     8281 gcaggttgtt cctgcgcttt ccggatagat agtccgattt ttccatcatc atttactgaa
     8341 ataactttaa ctgttacttc atctcctaca cttaaaacat catggatgtc ttttacatag
     8401 ccatttgaca cttcgctaat atgaactaga cccgtttttc cagcacctag atcaataaac
     8461 gcaccaaaat ttgtgattcc tgatactttt ccttgcagtt ttgctcctac ctcgattgac
     8521 ataaaaaaaa tgttcctcct aattatttcc cttttttata ttcctgctta ttttgcagtt
     8581 gtagaactag ttgattgatc tgtttcattt gtcgagctgt ctgtatttga ttctaatata
     8641 ggataaactt tttcaccgtc ttttgagtaa aagaatttgc ttctggcaag tttagctaca
     8701 tactcatcat ctttcagcaa tgaaacatct tggtgcagct gatcaacgtc tgcgttgact
     8761 tctttcattt cagtatttgc ttcgactctc aattcgttca attgatgcat cctttgcatg
     8821 tcatggaaaa tctgcacacc tattatcgcg aaaatgacca aagcaccaac aaaaattgca
     8881 gccagtctgc gtcttcgaaa aatcagttga cgttgttgtt gctgaaattc agcatacttt
     8941 ttctttgcat attccgtatc tagcgcagcg attttattgc tttttttcgt cacttggatt
     9001 cgctccaatc tttttgattg tctttttcat tataccaata tcgtgaaagc ttgtctaatc
     9061 tatttctcta gtgtttctgt gcgattttca gaaataattt cgtacatttt ttgtgcatct
     9121 tcttttttgg ttgattcatg taattccgta attttcactt ccaacgtttt gttgccaaac
     9181 tggactttca aaatatcgcc tactttgaca tcactggaag atttcgccaa tttaccgttg
     9241 atttgaattc ttcctttatc agctacttct tttgctactg atcgtctttt gatgattcgg
     9301 gaaattttta aaaatttatc taatcgcata tcttattcct cactttttaa tttttttatt
     9361 taatcgcagg attttcttac caaaaggcaa cattagccat tctcgtactg taaacagacg
     9421 aagacgaatc actgcataaa tgaacacaga agccccgatc ccaactccta tcacgctgac
     9481 aaaaaaagca gtggaacgat gagttacagg accaaatact atattcaata caccataata
     9541 cagcagcagt actactgtca tacaaagaag gctgaacatc aacttccgtc caaaatgccg
     9601 ttctttccaa aaagcattta gctcttttgt ttcaattcga acaaaatacc aaagcgtcac
     9661 acctaatcct aaaagggtag acaggcttgc acctgctgtt cctaataaac cggtcagaaa
     9721 agaagtagtc aatcctttta ccaatagtcc ccatcctgcg ccttttaaag aagggcgaaa
     9781 cgagttcttg ctttgagcaa tactttgata agcttggatg actgcagtga aagcaatgga
     9841 aaaaacaaat aatacaagcg ctgcatttcc cgcataatct ttaaacaacg cataattgat
     9901 ataagggagc agcaaggcta atcccaaaga cgcagctaat gctaaagcgg tcgtcaatct
     9961 aagatagatt ttggctgtct gtaaaaactg acgatagatc cggttggtca aatgacgagt
    10021 caacgcaggc aggaatgtcg cacttaatgc agtggcaatc actaaaccta attgtactaa
    10081 aggctgacct cgatcataga ccccttttgc tatcttcgca ccgtattctg acagtccgta
    10141 aacttccaaa gcatttttta caaagaaaga gtcgatcagc tggaaaaaga taagcaatcc
    10201 actataaatc gaaaccagtc cgccttctac cagaaaacgc cggatcaagg gctttgacgg
    10261 ctgtttgaac aatggaaacc gtcggaagct taacgctcct ccatgaatct tttgttcata
    10321 gtagtgaagg atcccatatg cgcataaacc gccaaaaaca gctccactca ttgctgccgt
    10381 ccctgtttgg tacaccgtcc atccaagctt tctaaaagca aacgcactac agacaatcac
    10441 aaaaacacga acgaactgct caactacttg agaaacagca gttggttcca tcaagaatct
    10501 tccttggaaa ttccctcgat aaaaagatag accaggcatc agcaaaaagg taaaggaaac
    10561 tacttggatc agcggtttca attgtatgtc tcccatcatc caagcaatcc agctgctaaa
    10621 tgcaaagaca aacaaccaca aaaagacacc tgtccaaaat actaagggat aaagattttg
    10681 caaagcttgc tttcgctcga aaggattctt tctttctgca acgtactttg atatgaactg
    10741 cggaagaccg gataaagcta aagtcattgc tatcccataa attggataaa cttgctgata
    10801 aacataaaaa ccttcgtcgc cgactaagtt ttggagggga attcggtaaa gggcacttaa
    10861 tacttttgct atgaaagaag caatcgtcaa tacaaatgct ccttgcatga cgcgccgcat
    10921 ttctttatga tccaaatcat tgctccttcc tacgctgaca gatatttttg ctcacgcaac
    10981 gctttgacaa acttttggat ttcctgaagc catactgctt cttccatttg gttggggatc
    11041 gtcaagcgta tcaccatctg ttctttttca acgcctagac tggcttttag ttttgtcgct
    11101 gtcagtgctt cgaataactg ttccacacta tagcgttttg ttccaacttt acttagagta
    11161 aagactatat gcgcctcctg tttccttatc gtttctagga gcgctcgatc gccatccatt
    11221 ttgatctgcc caattgtcaa gagatgtgct acttcttctg gatattctcc aaaacggtcg
    11281 agcagatcat cttctagttc atctagcatt tcttgcgaat caagttcacg aattcgttta
    11341 tagatctcga ttttctgccg ttgatctgcc acgtatgttt caggtagata cgcatcgaca
    11401 ccgaggtcga tctcaacagt ggtcttctcc acttgactat tctttccttg tttacgagaa
    11461 acagcttcgc ttagcatttg agaatacata tcgaaaccga ctgcatcaat aaatccatgc
    11521 tgctgagcac ctaagagatt acctgcaccg cgaatggaaa gatcccgcat cgcaatcttg
    11581 aatccagatc ccagttctgt aaaatctttg attgcctgaa gacgtttttc actgacttcg
    11641 ttaaggatct tctgctgctc atacataaag taagcatatg cgacacggct gcttcttcct
    11701 acccgccctc gcaattggta taacgtggat aatcccatat aatcagcgtt ctcaacgaac
    11761 aacgtatttg cgttcgggat atctactcct gtttcaatga tggttgtagt gacaagaaca
    11821 tcatattgac cttcaataaa ttcaaaaagc gtattttcta attgcgcctc tgtcatttgc
    11881 ccatgagcat aaccgatccg tgcttccgga acgagttctt ggatttcttc tactttttgt
    11941 tcgatcgttt ctacccgatt atataaatag aatacttgtc cacctcgtcc catttctcga
    12001 tggattgctt cgcgaatagc cccaggattt ttttccataa catacgtttg gatcggataa
    12061 cgattcgcag gcggtgtttc gattactgaa agatcccgca cgcctaacat cgacatatgc
    12121 aaagttctcg gaatcggtgt tgcagtcaga gtcaaaacat ccacttgtgc acgtaactgt
    12181 ttcaatcgtt ccttatgttt tacaccaaaa cgttgttctt cgtcaatgat cagtagaccc
    12241 aaatcgctaa attcaatatc ttttgacaaa attcggtggg ttcctacaac aatatcaact
    12301 tgacctgtac gcagttgttc gatggtttct ttttgttgct ttcttgttct gaaacgactt
    12361 aatagcccga tatttacggg gaaaccttca aatctttcca gcatcgtttc atagtgctgc
    12421 tgtgccaaga tcgttgttgg aactaaaaag gctacttgtt tgctttcctt tatcgcttta
    12481 aaggccgctc gaagcgctac ttctgttttc ccataaccaa catcacctac gagtagtcga
    12541 tccattggtt tttctttttc catatcccgt ttgatctccg ctgcacttct caactggtca
    12601 tcagtttcag agtaggggaa ggcattttcg aattcttttt ggtaggcgtc atcaggtcca
    12661 aaagcatatc ctttttctga ctctcttgcg gcatataatt tgattagatc gtcagcgata
    12721 tcctcgattt ttgaagagac ttttcgcttg gttttcgtcc attcacttcc gcctagctta
    12781 ttgatgcgag gcgctttggc ttcagaggcg acatattttt ggatcagatt cagttgagta
    12841 acaggaataa acagtttgtc gtcgttttga tacaaaatag tcatatagtc ttggtgaacg
    12901 ccatctactt ctagcgtttc catcccaatg tatttcccga taccatgatt ggcatggaca
    12961 acgtaatctc ctgcttttaa ctcattatag cttttcaatc gctctgcgtt tgttactgtt
    13021 tgacgtctcg tttgtttttt cgtcgttttt tggaaaattt ctttttctgt gatagctact
    13081 attttttctt gaggaagttc aaaaccagcc tgcaaagctc cttcaactaa ttgtacctgt
    13141 cctctgatca atgcattttt ttctgtttct actactaata tgtcttcatc tcgaagcatt
    13201 tgttctgctt tgcgtattct gtcctttgtc ggaataaaga tcacaacagt ctgtttttgc
    13261 ttgcgccaac ggtccatttc tgttttcagc aatggcattt gtccgaagaa ctgttgcatc
    13321 gtccgatatt gaaaattatg gattgcttgg aaacgaagat ttcccatccc tttttggaag
    13381 agtgagaaaa aggttgtggt gaacttttcc ttctgcacga ttttttgtat atctgctgaa
    13441 aatgtctgct cagaaaacac ccgcaattcg ctgatttttt gagtctgcca ttctgccgct
    13501 tccctttcga tttcccgatt tgtttccatg attcgctgat aatcatcaac gactagtaaa
    13561 ctatttgaag ggaaataatc caagatcgtc acagattctt ggtaaagaag atctgagtag
    13621 aattttgctt cttctgtcgg gacacctgct tgccagcttg aagtcagctg accgaagtaa
    13681 tcttgcaaaa actcgcggtc tgcttcttct gtggtcgcag caagccgttt ttctagcatt
    13741 ttttgcattt gctctattcc atgttctaga tcctctggtc cgtagacttg ttcactcgtt
    13801 ggggaaaccc agatttcttc cgttttttcg attgagcgtt gtgtttctgc ttcaaaatac
    13861 cgcatagaat ctatctctac atcaaatagt tctacacgaa caggataggt tgtcgttaac
    13921 gggtaaatat cgataatgct tcctcgaata ctgaattctc ccggttttgc gaccatctct
    13981 tctcgtacat agcccatcaa agtcaattgg cgaggaagat tttccacgtc tatctcatca
    14041 ccaatatgcc aattcaattg cgcctgtagc caagttttct tattcggcag tcgtttgtgc
    14101 aaagatgcga ctggcaacaa atagatacct gctttttttt cttgaagtgc gttaagcgtt
    14161 gcaactctct cgcctcgcgc ttctggagaa gaaaaggcca tttcagcaga aagcacttca
    14221 tccactggaa ataaatggat ctgatcttgc ggaatcacat gttgcagatc ttctgctaac
    14281 tgattcgcat aatacaaatt tggcatcaga ataatcatgt ttttatttgt tttcttaaac
    14341 gctcgagcaa atagaagtgt tttcgctgag cccgctaatc ctgtgattag ttgtctaggc
    14401 attttttctt ctaaattgct gacccattct tttacttgcg gatcttttcc gactaattga
    14461 ataatatcca ttccttttcc tccttcctca attgaatcga ttcatcgcat ccacgaacga
    14521 atgcccttct atgagatatt cgactgcttt aacagattga cacatgcttt cttctatcaa
    14581 aggctgattt tctttgctga aaggactaag cacatgctgg actactgttt ttttcccttc
    14641 tggcctgccg attcccacct tgattcgatc aaagacattc gtattcaaat gggaaataat
    14701 acttttgata ccgttatgcc cgccggcact tcccttttga cggagccgga tttttcccac
    14761 tgccagatcc aaatcatcgt agattacgac taattcctct ggataaatcc caaaataagt
    14821 cattagtggg ccgactgcac gaccagattc attcatgaat gtttgtggtt tgactaaaag
    14881 gatcttttct ccattatgaa aaaattcggc aacttctgct tcgaacggat tttttttgaa
    14941 agtagcttga tgctcgcgtg caattttatc cacgaccata aagccgatat tgtgttttgt
    15001 atattggtat ttggtacctg ggtttcctaa cccgacgatc attttcattt ttgttttcca
    15061 cctaattcta aaaagcagca caaaaggctg gactgctaat tagcggtcca gtccatcgag
    15121 cttttttctt ttttacactt gtcaatgcat agtataacac aaaacaaggc gtttcggcta
    15181 aaagagaatc gttaataaat gataaagaaa ttaaaaattt cttcaaagtt taatgaaata
    15241 attgatatat aaaaatagtg aaataacgca catgtaagct tttacatata atacaacctt
    15301 gttatctgtt atattttata gccaaatagc gtgacatggg gcttgagaaa tgttagcata
    15361 agcatgggaa aaaacaaatc aatggaagga ttgatactaa atgactgcag ctgcagaaaa
    15421 aaaagatcat caaaaagtta ttcttgttgg agacggcgcc gtaggttcta gctatgcctt
    15481 tgctctagtt actcaaaata tcgctcaaga agtaggtatt gtggatatca atactgctaa
    15541 aactgaagga gacgcaattg acttgtctca cgctttggca tttacttcac ctaaaaaaat
    15601 ctattctgct acttacgcag acgcacatga tgctgactta gttgttatta cagctggcgc
    15661 accacaaaaa ccaggtgaaa ctcgtttaga cttagtaaac aaaaacctaa aaatcaaccg
    15721 cgatgttgtc acacaaatcg ttgaatcagg atttaacggt atctttttag ttgccgctaa
    15781 cccagtagat attttgactt actcaacttg gaaattctca ggtttcccta aagaacgcgt
    15841 aatcggttca ggtacctctc ttgactcagc tcgtttccgt caagcacttg cggaattagt
    15901 tgacgttgat gcacgtaacg tccatgctta catcttaggt gaacacggag attcagaatt
    15961 cccagtttgg tcacatgcaa atgttgccgg cttgcaaatc tatgaatggg taaaaaacaa
    16021 cccagaaatc gatgaagaag ctatggttaa cctattcttt ggcgtacgtg acgctgctta
    16081 cacaattatc gagaaaaaag gcgctacttt ctatggtatc gcagtagcat tagcacgtat
    16141 cactcgtgcc atcttagatg atgaaaatgc tgttcttcct ttatcagtat tcatgaatgg
    16201 cgaatatgga ttgaacgaca tctacattgg tgcacctgct gttatcaacc gtcaaggtat
    16261 ccaaaaagta atcgaaattc ctttaagtga cagcgagcaa gaccgtatgg ctgcttctgc
    16321 taagcaatta aaagaaattc tagatgaagc ttttgctaaa ctagacgctg aataatcttt
    16381 gaacatgacg gaaaacatct attcggtgtt ttccgttttt ttattttatc acccttatgg
    16441 tttctaaatt ttttcataaa gtagagataa ccttcgtctt ttcctctaaa ttatgctatc
    16501 atgagaccgt tccaccctaa acttttactt aaggagttgt cgatatgaca agatcttcgc
    16561 atcgaaaaaa atcgaaacat gttgctttgc tttcagttct tggtgttctc ttagtgctga
    16621 tcagctttta tacctatcgc agtacatact acacaaagca ttttttgccg aatacagaaa
    16681 taaatggaat aaatgtcagc aatctaacag tcgaaaaagc aaatgaaaaa ttaaaagaag
    16741 cttattctga taaaaaactg gctattaaag aagatggaaa agtctggcag gaagtaccaa
    16801 aatccgagct cggctacaaa gatgatttca cttcggagct ttctccgatc ctaaatgaac
    16861 aaaacggatg gacttgggga atgacttatg tctcagcggc agaaaaacaa gaaatagatc
    16921 ctgtcagtca aaaccaccaa aaactagaca ctaccgttca gacattgaca actaagctga
    16981 ctgatttgaa caaagaccgg acacctacta ctgatgcaac gatcgaaaaa gcaggtgact
    17041 ctttcgttat caagcctgaa gtcaatggaa atacgatcga cgtcgatgct gcggtcaaac
    17101 aattaaaaag tgcggtaaac tctggtaaag atacaattga attgactgaa ttcaaagaaa
    17161 aaccaaaagt aacatctgaa gacagctcac tgaaagaaca actcgcatcc atgaatgcta
    17221 tcgcaaatgt aaaagctact tacagtataa acggtgagac tttccagatc ccatcaagtg
    17281 atattatgag ttggctgacc tacaatgatg gaaaagtcga tttagataca gaacaagtac
    17341 gtcaatatgt aacagattta ggcacaaagt ataacacaag tacgaatgac acaaaattta
    17401 aaagtacaaa aagaggagaa gttacggtcc cagttggcac ttacagttgg acgatccaaa
    17461 cagacagtga gacagaagca ttgaaaaaag cgattctggc aggccaagat tttactcgtt
    17521 cacccattgt gcaaggtggc acaaccgctg atcatccatt gatcgaagat acgtatatcg
    17581 aagttgatct ggagaaccag catatgtggt attacaaaga cggaaaagtg gcccttgaaa
    17641 cagatatcgt ttccggaaag ccaactacac ctacacctgc tggagtcttc tatgtttgga
    17701 ataaagaaga agatgcaact ttaaaaggaa caaatgacga tggaacacct tacgagagtc
    17761 cggtaaacta ctggatgccg attgactgga caggtgttgg tatccacgat tcagactggc
    17821 aacctgaata cggtggagac ttatggaaaa cccgcggttc acacggctgc atcaacaccc
    17881 caccaagtgt aatgaaggaa ttattcggga tggtcgaaaa aggaacgcct gtattggtct
    17941 tctaacaaaa ataatatata aaaagaaagc acccgtacga ttggtacagg tgctttcttt
    18001 ttattatcta acaatgtgct acttacattt cagcagcagt aaagacttct gaaacatcat
    18061 catcgtcttc tagcttatct actagacgtt ccaattgctc tttttgttcc tcatttaaat
    18121 caatcgtcgt ttgtggaatc atcgtcaatt ctgcttgcgc caaagtgaac tctttttcca
    18181 actcatctcg tacagcagca aaatcttctg gtgcagtata aatctcgaat acttcaggag
    18241 aagtttgcag atcttctgcc cccgcctcta atacatcctc aaacatcgtc tcttcatcaa
    18301 cagtcaaccc atcgcgttca atagcgatat atcctttgcg gtcaaacaag taactgactg
    18361 aacccgtttc tcccagtgat ccaccgtttc gagtaaaagc tactcggaca tttgtcgctg
    18421 tccgattacg gttatctgtc aatgcatgga ctaagattcc tactccaccc ggaccatatc
    18481 cttcatacgt gatttcatcg taattcgttt catctacggc actcgtagcc tttttaatcg
    18541 cccgttccac attgtcgtta ggcatatttg cagcttttgc tttgtccaca acaagccgca
    18601 aagctggatt catagatgga tcaggaccgc ctgctttagc tgccatataa atttcacgag
    18661 aaagtttctg aaagactttc cctcgttttg catcttgggc attttttctt ccttggatat
    18721 tatgccattt actatgtcct gacatgattt ttcctccctt gttcttttga gaatacactt
    18781 ctattctagt actatttcac aaaaaaacaa agccacagcc aatctataaa cgcttcttga
    18841 atgccgcaaa aagcacacat aatatcacag cagtcagagc accgatcgaa tccaacatga
    18901 catcttggaa cataggtgtt cgtccaccgg tcatcatctg atggaattcg tccaaacctg
    18961 cgtaccctgt tgctgaaagc caagcaagga tcgctgtcag ccaccaaatt tttagcttgg
    19021 ggaaaacacc taaaaacaag ctgcctccca aaataaaata ggtaccgaaa tgtgcgccct
    19081 tccttaaaaa gaactctaaa aatttggcgt agcccagatg gttgatactc accatacttc
    19141 caccataatt aaaacgtata cccgctaatg tgtctttaaa tggctgatta ggcagccagc
    19201 tttctaatcg cgaaacttgt gattgctgtc cgtaagtttg agaagaactg taaaataaga
    19261 ttataacgac tatcagtgcg attactaaat aaatatttcc gtttttcatt tgtttttttg
    19321 aagaattcat aagtcacctc tgtattttat cttagacttt ttttgaagaa acaacaatca
    19381 ttttcataga gacttcttcc ataaaaaagt gctatactta attttgtatt acaatatgaa
    19441 gggagttttt tcatgagtta ttcattaaat tggaatctag attctatttt ttccggaggc
    19501 agtcattctg atgctttgaa ccaacggatg aagcaattgg aagaccaaat gaacgagtat
    19561 tatcaccgcg taacaaaatg gtcacctagt tctgacaatg cagagcagtt aaacgctatt
    19621 cttcaattgc aagaaacgat tacgaatggt tttacccaat gcagcagcta tattactgca
    19681 ttgctttctg ccaatgtcaa tgattcagat gcaaaggtct tatcaggcaa gctttacgca
    19741 atgctgcctc gtctgcaatc agccgaaact gtattgtcaa agaaatttgc agaaatatct
    19801 gacaatgatt ggaatcagat gctttctcaa tcttcgtttg aaacaattgc ttttcgttta
    19861 aacgagattc gtcgtgatgg ctcacaatta ttatcagaag ctgaagaaaa cattataaat
    19921 acgctttctt tagatggtct aaatgcttgg agcagtcatt atgatacgat tgtagccagc
    19981 atttcgattc ccttcgaaca agatggacaa gtagtcgaat tatctgctgg acaagccttc
    20041 aataagatga tgggcgatcc agatccaaaa gtcagagaaa cacttttcgc agcatgggaa
    20101 gaagcctgga aagaaaaggc acccctcttc acggatactt tgaatcattt agatggtttt
    20161 agactttctg actatgaact tcatggtgtc acagattttc tacaaaaacc attagagtac
    20221 aatcggttga agaaagaaac attgtctgtc atgtgggata caatccagaa aaacaaacaa
    20281 ccccttgtta attacttgac tagaaaagct aatcttttcg gtaaagaaaa aatggaatgg
    20341 caagatcaag atgcacctat tattttaggc gatttgaaag aaaaaacctt tagttttgac
    20401 gaagcagcag catttattat cgaaaacttt aacaaattca gtccaaaaat ggctaaattt
    20461 gcccaatctg cttttgaaaa gagctggatc gaagcagaag atcgtcctgg gaaacgtcct
    20521 ggtggttatt gtactgagtt accagaaaca aaagaatcaa ggatctttat gacctacagt
    20581 aattctgtta atgaggttgc gacacttgct catgaactag gacatgcttt ccatagcagc
    20641 acgatgtggg atttaccttc tttaaatcgc gaatatgcca tgaatgtcgc agaaacagca
    20701 agtacattcg cagaactgat cgtagccgat gctacattaa aagtcgcaaa aacaaaagaa
    20761 gaaaaaatca atttgctaga tacaaaactg caaaatgctt tagctatgtt catgaatatc
    20821 cattcccgat tcatttttga aaatcgattc tatgaagcac ggcaagaagg attagtctca
    20881 gaagataaga tcacagagat gatggttgag gcgcaaaaag aaggctatca aggagcttta
    20941 gctacttacc atccatattt ctgggctgca aaattgcatt tctttattga tgacgtaccg
    21001 ttttataact tcccatacac atttggctac ctctttagtt tgggcatcta tgcttacgcc
    21061 aaccaaaagg gagcaaattt tgaagaagaa tatatccatt tactacgcga tactgcctca
    21121 atgacgacgg aagatcttgc gaagaaacat ttgaatgtcg atcttaccca accagatttt
    21181 tggcaagcag gtatcgacat ggtgactgaa gatatccaaa cgttcatgga attgacagaa
    21241 gaatttatct gatttctatt ttatcacaat aaaaaaagag ttagtccaga atgggctaac
    21301 tctttttgat taatcattct tacatgctga cagcaaagtc aggggcaaac cattgaactg
    21361 aaccaacttt tacgctttcg cctggttgag gagcatggat atattgtcct ccgcctaaag
    21421 caatcgctac gtggtaagtt ccgccttgtg acccccagaa taacaagtct ccagcttttg
    21481 cttgagaaac tgaaattttt gttccagctg attcttgagg aactgtccaa ccaccgatgt
    21541 cacgaccagt tacttgcatg taaacatagc gtgtgaaccc tgagcagtca aagccacttg
    21601 gatctttacc gccccaaaca tatggagtac caatatattt gtaagcttct gctacgattg
    21661 ctgcaccatt cacacttcca gaaggagctg gagcaggtgt tacaggtttt ggttgttcag
    21721 gtgttggtgt tggcgttgga gccggagtac tacttcctgt gccgtttcct gtatcaacac
    21781 tttgatctgt tgatggtgtt gtaggcgcag gtgttgttga ttcttctgtt gttgaagatt
    21841 caggcactgt tgttgattct tctgttgctg aagattcagg cactgttgtt gattcttctg
    21901 ttgctgaaga ttcaggcgct gttgttgatt cttctgttgc tgaagattca ggcgctgttg
    21961 attcttctgt tgaagattca ggtgttgttg attcttctgt tgctgaagat tgtgtagctg
    22021 atgatgattc ttcagtcatt gaagattgtg tagctgatga ttcttctgtt gctgagcttt
    22081 gtgcagtaga tgaagcttga gtagcttgtg cttcagcctc tgcttgttcg cgtgcttctt
    22141 tttcagcttt ttcttgtgca gcttgttgac gagcttgttc tgctagacgt tgttgttcac
    22201 gaatacgagc ttgctctgct tcagcttctg ctttttgacg gttcaagtca gctttcttgt
    22261 cttcagcagt tgcttgttca gcagctaatg aagttttcag tacgttcaaa tcagcttgtt
    22321 tagataaaag atcgcctttt tgagattcca aagcagcttg gttttcagct aattctttta
    22381 gtttagcatc gttttcagct tttttgtctt ctacagcttt tttatcttgt ttttgttgtt
    22441 ccatcaagtc gttgtttgct tttaccatcg ttgtcattgc ttgaacgcgt ccaatagcat
    22501 ctgctaatga atcagcattc aatacagcat cgatgtagtt tgagcttgtg ttgcttactt
    22561 gtgcttcgcg tgcttgtttt tggattgtat cttcacgttt ttcaatacgt tcttgtaaat
    22621 ctgcaatgtc ttttactaat tgtgcagatt cttgacgcaa tgtatcttgt tttgctaata
    22681 ggtcttgtgc ttgtgtgttg atttcagaaa cttggctttc taaggcatcg atttgtgatt
    22741 gtgcatctgc ttgttgattt ttcaagtctg caatcttttg atcttgctgt tgtatctgag
    22801 aatcaaaatc gtccgccgcg gcagcgatcg gtgatgctac ggcagtcaag gtcattgaac
    22861 ataccattac tgctgatatt aaactctttt tcactcttca ttcctccgac tggcttaatt
    22921 taataaatat ctaaatatat ttaagtcttt cttaacgata taaaaattgt accatagcag
    22981 tgtgtcaacg atataatagt tatgttacaa aaatgtttca aaacaacttt taaaaatgac
    23041 aaaactgttc gtttcagaaa atgatcatga aaaagccgcg ttaagtctag catttcttaa
    23101 gataacaacg attctttttc gctttcgacc taaaaataaa aaaagaaatt attcatcact
    23161 gaataatttc ttaaagggaa aaatgaataa tacaaatata atcatgttca acagcagtgt
    23221 aggtcctaaa aaccttgtaa taaaatacgt gttatttact actgctaatt taaaaatcaa
    23281 ctggaccacc atcgtaaaca attcataacc cgtgacaaag atgatcatac tgaaaaattc
    23341 agtaaagatg ttgacatgga taacgtcttt cattacatac atcaaccata caattaaagg
    23401 gagagctact gcatagatac cgataacgcc aatatagtaa gcgtcataga tagccccgag
    23461 aacaatcgtg gtaatcagta aataacgttt ttcaaacgcc atactgcaac ataataatgc
    23521 caatatcaga aagtgggcat ttgacatata ggtgcctttc gaccactccc ctagcattct
    23581 tgttaaatga ccatctatca acatcaaaaa gaacaaaacg attggcagat agtacttcat
    23641 tgtttctttc ttcaacatgg actaatcctc cgctagccgt tggacaatcg tcacaactga
    23701 cacgtcatac atttctgcat aaggtttcac ataaacttcc cgatccagcc cataactatc
    23761 tggtttcgtt ttaataaccg taccgatcgg caagttagct ggagaattcc ctccaagacc
    23821 ggatgtctgg acaacatccc cttctttgat atccgtatca ccagttaatt gggtcaccac
    23881 taaggcatgg agcttttcat catagttttt aagcaaacca aacgcttcgc cattagccga
    23941 agatacccgt actggaaaat gattggagct ttcattagag gatgacagta attcgatttt
    24001 agacgaagcc gtattgacct cgatcactcg gccaatcaat cctttttgcg acatgactgc
    24061 catatttgct tcgataccgt ctttagaacc cttgtctacg atcagcatgt cctgccaact
    24121 gtcaggcgaa cgagtaatga catttgccgt tactttttcg taactagtca gcgtctgatt
    24181 caactcaagt tcttttttca acgcttcgat ttctctctcg taattcttgt tttgctgtga
    24241 aacgtcatca tagctatcga ttttttcttt tagccgctca ttttcggcat aagttgaaaa
    24301 aagattatgg acagaatcta ctccatttcg tacccaccgt actggggcag agattgtttt
    24361 atcaaccatt gcaacactgt cattaacgat ggattggaag aaattgggct ttccttcatt
    24421 cgctcgctgc gcagcggtca cacttagtat cgtcaccacg atgataacaa taaccaaggt
    24481 aataataata tttttattag gattgaactt cttcacaaag acacctcgaa ttaattagac
    24541 tcttgtgttc aattttatca ctaaatgccg tgaaacaaaa ggtaagttgc tcctcttaag
    24601 ctttttttta gcaaataata gattctgtca tttttagcct gaaagacaaa tttttttatt
    24661 tgtttatgga tcaatctttg ctttgaataa ctgcaatcat accatctgaa aaagaaaatt
    24721 ctgcggtatc tgaaagaaat tcgttacttg cataagatgt cggatattct acttctttat
    24781 tttccaatac atacttgctg ccttttaatg taagattcga gacgggagtc aagcagcaat
    24841 aagctaaata cttcatatct ggtatctgtc ttactatatg ctctccaggc aaataataag
    24901 acaaataatt ttgacaatct ctgataataa gctgatgggc aaagggtttg aagcgaggtt
    24961 ccatacctaa ccagagattg gctaaaagat gatccaatct tccgcccgta gctccaatca
    25021 aagtgacttc cgcttgcggg taacgttcaa atgtttttaa gatacctaac tgtgtatctg
    25081 tatcgtcttt ttctgcaggg gaacgggtat actctttggc ttttgcaaat acttccttct
    25141 gctcttcgtt cgacaatgaa tcaaaatcac ccactgccag atctactggg tagcctgctt
    25201 gaagcaggta cagcgcacca cggtctatcc cgacataggc atcgtatttg gacagcagag
    25261 actgcggcca gttttgcgga ttacctccag cagctaataa aattttcatt tagtctaatg
    25321 cctcttttaa tcgttcgatt tgtccgactg gattttcggc tccatagata tatgatcctg
    25381 caacgaagac atccgcccct gcatctttac agatttttgc tgtttctgga acgattccgc
    25441 catctacttc gattgcataa gtccaattgt tctctctacg tagatcagcg agttccgtaa
    25501 ttttttctac tgtttcttca ataaagcttt gtccgccgaa cccaggattg acagtcatga
    25561 ctagtacttg atcagccaaa ggcaaaacat gtttgatcat ggagactggt gttcctggat
    25621 tgataactac tccagcttta actcctaagc tttttgtcat ttgaagtgcc cgatgaatat
    25681 gaggagttgc ttcgacgtgg acagtaatga tatctgctcc agcttttgca aatgctggaa
    25741 tgtagttttc tggatcaacg atcatcagat ggacgtctaa cggtaattta gtaacaggac
    25801 ggattgcctg aacaatattt ggccctaatg tgatatttgg gacaaatcgg ccatccatta
    25861 catctacgtg gatgtaatct gcgcctcctt tttccactaa ctcaatgtct ctttgtaaat
    25921 tggcaaaatc tgcactcaaa atggatggtg ctatcttcat tcttgtttcc tcctattttc
    25981 gtttaccttc tttttttgca tacattggtt ttcttttttc gatttcttgt aagaattgca
    26041 aataattgtc gtaacgtgtc tgtgcgatac cacctgtttc tactctatgt tttacttcgc
    26101 agccaggttc tttagcatgc atgcactctc taaatttgca atggacagaa gcttctacaa
    26161 attcaggaaa ttgtctcggc agttctcctg cttcaattgt caaaaagtca atcgagctaa
    26221 atcctggtgt atctgctact aacccgccat agataggaat cagttccaca tgacgtgttg
    26281 tatgccgtcc tcttccaagt gcatcagaaa tctctcctgt tgctaaattc agttccggtg
    26341 atatttgatt cagtagcgtc gattttcctg ctccagactg acccataaag accgatagcc
    26401 gttctgggaa gtaacggatc agttctgtcg tatcacccgt atgattgggt acaatcaccg
    26461 gatagcctat tttagtatag gtttgcttga tctcttcgat tttttctggg tcgtctgaca
    26521 agtcggtctt tgtcaaaaaa ataatcggtt cgatcgactc gtattccaag gtaactagaa
    26581 agcggtcaag tagattataa gaaaatgcag gctctacgat acttgtgaca atgattccaa
    26641 gatcaacatt tgtgactggt gggcgaacta attgattttt tctcggcaag atttccagaa
    26701 gatagccgtc tgtttgattt tcactctcaa agatcacctg atctccgaca agcggcgtga
    26761 ttttccgatt ccggaaattt cctcttcctc ttgtttgata ggtctctccg tttgcgtata
    26821 catagtaaaa accgctgatt gcttttctga tttgtccttt gataagtgcc acctccgttt
    26881 ttgtttattt taccatacga agaggaaagt aggtgttatt ccatgcaaac ttctcaaagt
    26941 atatggcttg aaaattgatc aaaagagata gaaacacaaa aaagagaatg caacaaatca
    27001 atgtcgcatt cccttctgat atattttatt cagcacttat tttgaacttt ctgaggtgct
    27061 agctgatgaa cttgtggagc tggaagattc ttcttttgaa gagttgcttg tgctactgga
    27121 gctacttgag ctgctagaac tgtctgaaga gtctttttca gaactagaag acgctggatc
    27181 tggtccttta gagtaaatta cgttcacaac cattcctttg gtaattgtcg ttcctgcccc
    27241 tggtactgta cgaatcactt tatctttatc caccgtgttt gaatattcgg aagtctcatg
    27301 cccgatatat tctgcaccga cactagctaa ataactttgt gcttcgcttt ttgtatagcc
    27361 ggagatatca ttcaatttag gctctgttcc ttggcttacg acaaaattga tgtaagtttc
    27421 ttctgctaca acttcacccg aggctggatc ctgactgatg atcgaacctg atggtacagt
    27481 gtcgctatag tcataagtag cactaatatt attgatattg aatccttgtg taacaagcca
    27541 attacgaaca gtttcgtagt tttctcctac atgactactc aaagtcactg tttctggtcc
    27601 tttgctgact gtgaaagtaa tcgtgtctgt tttaggatcg acttctgtat cttctgatgg
    27661 agattgcgaa atgatcattc cgctttctac ctctgaactg aattcctctt ctttttgaat
    27721 caagtcagca gaaaacccta attctttcaa acttgcttcg gcatcttcat aacttttacc
    27781 actgtaatca tctaatttga tttttttcgt gccgctacta atatacagag tgacttcgcg
    27841 tttttgcttg actgtcgttc ccgctgccgg gtctgtcttc actacattac cttcttcgat
    27901 tttgtcatct gcaatttctt ctgtttttgt tgctacttct aatttcgctt ttgcgagtgt
    27961 ttctctagca gaagcttcag aaagatcaga aacatcagga acaacaactt ctcctcgccc
    28021 gccagaagca aagaatacag ctgttccgat tcctaaaaca gcaagaatag ctaataggat
    28081 cagccaccat tttttctgtc ctttcttttt aggatcaggc agaacttctt cctcctctgg
    28141 taaggtttcg ttttctggct tgtcttttgg cagaggcata gatttgaatg aatcaggcat
    28201 tggtgcatct tccgtaaggg gtgtgataac ttttgtttca ttatccatca catgaggctg
    28261 ccatttttct tcgtttgcac gagctggtga taatactgta gaaagatcat cagacatttc
    28321 ctcggctgac ttataacggt ctgcaggttc tttagccgtt gcccgtaaaa tcacgttttc
    28381 cagtgcttgt ggcacatttg gatcaagtgc ttttatagat ggaagatcat cttgaaaatg
    28441 ttttaaagca attgttacag cagattcacc atcaaacggt acgctacccg tcaacatctc
    28501 ataaaggatg atccctaaag cataaatatc tgactgcttc gttgccatac ttcctctggc
    28561 ctgctcaggg gacagataat gaacagatcc tagcatcgta ttcgtctgcg tgatcgatgt
    28621 ttcagataaa gcgatagcaa tcccgaaatc cgtgattttt acaacacctt cattatcgat
    28681 cagtacgttt tggggtttca aatctcggtg gatgatttga tggttatgag ctaaagaaat
    28741 agcagaaagg atctgctgca taatatttac tgctgtttca taaggaacag gataatgtgt
    28801 ttggatatat cgtttcaagt ccattccttt gacgtattcc atcaccagat actgcatgtt
    28861 gtcttcttca ccaacatcgt aaacactaac aatgtttgga tgaacgagtt ctgttgctgc
    28921 taaagcttct ctctgaaatc gtcgaatcgc agtctggtca ttttgaaagt caaatcgtaa
    28981 gactttaact gctacatcac gatccaagat taaatcgtgc gccaaaaata catttgccat
    29041 accaccgcta ccgatatttc cagtgatttg ataacggcca tttaattttt tgcccaactc
    29101 gatcatacac tgtcctcctt atattcgata agaagaacgg tgatattatc cgctccgcct
    29161 gcttcattgg cacgatcaat cagctcagtt actttatgag acaatgggcc ttcttgattg
    29221 atgatcgttc ctatttcttc ttcagacagc atgttcgtca agccatctga acataacagc
    29281 agtcgatctt ttagttgcca aagatgagta gaaacatcta cttcgactgt tccaggcatg
    29341 ccgacagaac gtgttaaaat atttttcctt ggatggttca ctgccatttc ttcgctgatt
    29401 tctcctgatt tgactagttc attgactaaa gaatgatcct ccgtcaattg catgatttta
    29461 tcttcacgaa tcaaataagc tctgctatcc ccaacattgg caatcgtgaa ccagtcatct
    29521 gacagagcgg ccgctacgat tgttgttccc ataccgttat attccggctg ttcttgtcca
    29581 cgctgataaa tcagcatatt ttcttcttga atcgattgaa tgaaccattg ggcgattttt
    29641 tcatcgtcaa cagcttcttg tttttcccaa gcttcgccta gattcgttac cgccatctga
    29701 ctggcaatgt ctccggcacg atgaccaccc atcccgtctg ctaatacagc aagcttgaga
    29761 cctgaacggc tggtaaatac actggcatag tcttgatttg tgttacgtcg tcttcctaca
    29821 tctgattgat attcaatctg cattttttca cctcattact ttttgcgcaa acaacaaatg
    29881 aaaaatccat ctgtgtaaaa ctgatgcgga tacaaagtca acattttctc ttcgattgat
    29941 gattgtagca taggattggt caaaacatca atcctctcaa aatcagggtg tctttccaag
    30001 aaagcagaaa caacgtcttg gttttcttct tttaagatcg tacaagtgct ataagtcaga
    30061 ataccggaag actttaaagt tggtgcgcag ctttctaaaa tttccaattg gatttttggt
    30121 aaattcgcta attcatccgg ctgtttttta taacgaatat ctggttttcg ccgaagcagc
    30181 ccaagacctg aacaaggcgc gtctactaaa atccgatcaa actgctctgc ttcgaactgt
    30241 ttactgactt ctctagcatc catcttttga gcgtagacag cagaagagac acctagacgt
    30301 gctgcattat cttcaatgag tttgactttg tgttcgtgta catctaaagc gaccacttct
    30361 ccaccgcatg acggatctaa aaaagaagca atatgcgtcg tcttacctcc gggtgctgca
    30421 caggcatcta agacatgatg ttcaggctcg atttgcatag acggcgctac aagcatcgaa
    30481 ctttcatctt ggatcgtcat gacgccatcg tggaacaatg agctagaagc taaatgccct
    30541 tttttcgcta ctataccgta tggactgact tggctttttt cagctgtgat ctcttcttct
    30601 tgcaaaacag tgatggcctg atctctggaa agtcggcgtg tatctactcg ggcactagca
    30661 tggctaggct gatatagcga taaaccgagc ttttcagttt cttcgtatcc gatttgatcc
    30721 accagtcgtt tcgtcatcca tagaggcagg ctgattttga cagaaagtct ttcgatagga
    30781 tcagcaatgc cttgcagatc tggtgctcct tgacgctgat aattcctcaa gacaccattt
    30841 acaaatttcc ctgtcccagg atttcctttt acttttgcga tttcgaccgc ctcgtttaaa
    30901 atagcatgtg cagggacttt atctaaaaat tctaattggt atacagaaag ataaagaagc
    30961 atcttgaccc agtcatccac tttttttgct ttagcgatca atggtgcaac gtaaaattcc
    31021 aatagtcgct gatggctaat cgtaccatag atcaattctg taaataaacc cacatctttt
    31081 tgatttagct cgctttgttt gatcatctca ttcaacaaaa gattcgagta ggcgccaccc
    31141 ttgttcactc gctctaatgt cagtaatgcc atatatcgta ctgatttttt cattttttta
    31201 gggatttttt tcattatttc acctgctgac caatctgaac ttgctgaccg cttccgttaa
    31261 ggaaatcatg tacggcctgt tttcctttac cagctggctg taattcattg atggctaaga
    31321 cggtctgttt accgcaagca atccatagat tttttttgtc tttccggatg atcgtaccag
    31381 gtgctttgtc tgtagtttct gccaatactt caaccgataa taatttccag cgtatgccct
    31441 cataggtcgt gaatgcaatt ggccaaggac gcattccgcg tacttggttg tcaatttctt
    31501 ctgcagtttt atgccaatcg attgcttctt gttcccgtgt gatgtttggc gaaaaagttg
    31561 cttctgactc gtcttgaggt actggttttt gtccatccaa aatattgggc aatgtttcta
    31621 gcaatagctt tcttcctaaa aggctaagct tttcaaacat cgtccctaca tcatcttgtt
    31681 tagtgattgg tatgctttct tgcgcataga ttccgcctgc atccattttt ttgatcattt
    31741 ccatgatcgt tacaccagtt tctttctccc cattcatgat ggcataatga acaggcgcac
    31801 ctccccgata tttaggaagt aaagaagcat ggacattgat tgcccctaat tttggtactt
    31861 gcaataactt ttcaggcaag aattggccaa atgccgcagt gacgatcaca tcaggcacca
    31921 attcaatgat ttcttccatt tctggcgaac cggagatttt ctctggctgc agcacacgga
    31981 taccgtgctt cagagccgct ttttttaccg gtgtcggcgt aattactcgt ttccgcccaa
    32041 ctggacggtc gggctgtgtt accactgcct ggatctcgta acctgattct atcagccctt
    32101 caagaatcgg cacagaaaaa gcaggtgtgc ccataaatac tagcttagtc atcaagatgt
    32161 tcctccatat attcttcaag ttcttcttcc gggatctgct gtatcatttt ctcaatgaac
    32221 aagataccgt ctaagtgatc gatttcatgc tggaaggcac gggctaaata gccaaaagcc
    32281 gtcacttcta tctcttctcc gtctcgatca taataacgca cggtcacttc atctgctcgc
    32341 ttgaccgttc catagacatg cggaatactg agacaacctt ctacgtcaag gctttcacct
    32401 tttgcttcga tgatttctgg gttaatcagt tcaaatttct cgccttcatc tacttcgatc
    32461 acagcaattc tcttgttttg tcctacttga ggagcagcga tccctattcc gtcattcgca
    32521 atcattgtct catataaatt gtctaataaa gcgattgtct cgtccgtgat tacatcgatt
    32581 ggctgagcag ttctttttaa tttatcatta gggtggatca atataggata gcgcataatt
    32641 tggccctttc ttaaataaag tttaatggtt cgttgtcaat tgccacaaaa agaccttgtc
    32701 gctgttcttt ctggcttcca ttcaaaattt catccaaaac atgaggaaga ttcggttcat
    32761 gtttatattt gatgattagt tgataataat atcggttttt cactctcaaa atcatgctgg
    32821 gcgttggccc taatagcaag ctttgagggc ttaacacttc ttttagctga ttggcaatct
    32881 gaaagatttt ctttgccgct acttgttctt caggatggct ggcggttatt ttcacagtaa
    32941 agtaataagg aggatagcct ccacgatgcc gtacatgcat ttcctgctga taaaactgct
    33001 cataattttg ttttttagcc aattctatgg cgtaatgttg aggattgaat gtttggatca
    33061 cgacttcgcc tgctttttcc gctcgccctg ctcgtcctga aacttgggta agcaattgga
    33121 atgtatgctc actagaacga aaatccggta aattcaggga ggtatcagca ttcaacaccc
    33181 caactaatgt cacttctgga aagtccaaac ctttagcaat catttgtgtc cctaataata
    33241 tatctgcttc ttttgcaccg aatttttgta aaatctgttc gtgtgcccct tttcttcgag
    33301 tggtatctac atccatacgc aaaatcctag cttgcggata aagttctcgg agttcctctt
    33361 ctactttttg agtacctgtt ccatagtagc ggattttatt gccgccacaa ttaggacagc
    33421 gattgggaat aggttcttca tgtccgcaat aatggcagcg cattgaacgt gtatccatat
    33481 gcagtgtaag agagatatcg caattaggac atggaagaac aaatccacag tccctacaca
    33541 tcacaaaaga cgaatatcct cgacgattga gcagtaggac agtttgttct tttttgtcta
    33601 atcgattttg tattttttcc tgcaaattag cagaaaaagt agaggtccga tgattctgaa
    33661 actcttcacg catatctacg atctcaatag ctggaagctg tgcagctgct ttggctcggt
    33721 ggtttaactg caataactga taaacgcctt tttgagctcg tgctcttgat tctaaagagg
    33781 gcgtcgcgct tcctagaact attgggcaat gatgatattt actgcgccaa attgctagat
    33841 ctctcgcatg ataacgcggt gtctcatctt gtttgtaact tgattcatgt tcttcatcga
    33901 taatgatcag cccgatattt ttcagcgggg caaaaatagc agatcgtgcg cctactacta
    33961 cttgcgcttc ttcccgctca atcttgcgcc attcatcata tttttcacct tgggaaagtc
    34021 cgctatgtaa gaccgcaact gattctccga agcgtccttt gaatcgctcg accatttgcg
    34081 gagtcaatgc gatttcaggc actaacataa tagccgtttt attttctgac aaaacatcag
    34141 cgattgcctg aagatatact tctgttttcc cgctgccagt gattccctcc agcaaaaaga
    34201 cctgatcttt ttgctgctga cctgctgtga tgatttgttc gacagcattt ttttgttctg
    34261 cattcagttc caatgccgtc gtttggtcaa atactcggtc tttataaggg tcgcgataac
    34321 gttctgattc tataaactcc agccagccct tttcttttcc ttgattcaag acagcagtac
    34381 tgattccttt atttttgaaa taagcaattg gttcttcttg gctcagttca gataaacaca
    34441 aaagaagttc tttttgtttc ttggcatttt gccgtaattt tgcccattct tcttcgattt
    34501 gcttttcagt taacaaagaa cggaccaaac gaatcgtttt tactttattt cgtgtatgga
    34561 cttcatattt gatatctact aattgctctt ggcgccagcg aatcaattga gaaaggctgc
    34621 cttcttcttc tgcttccttc caggaaatca cttctcgctg atcaaacaat acctgaactt
    34681 ctggtgtgtc tgccaaagga tagatcaatt tatcatattc tgctttcatc acactcggaa
    34741 gcatcgtttg tagacaagtg attttgaatg cgtaagtaat ttttttcata taatcagcta
    34801 atgaaagtaa ttcttcattg accaccggag caaggtctag caaacgaata actgccttca
    34861 aagatggatt agctgattct tctgattttt ggatagccat aacaaatcct tggacatgac
    34921 gattgccatt accaaaaggg acttctactc gcatcccgac ttgcaaagct gtttccattt
    34981 cagagggaac caaataagtg aatggctgat cggtctgcat agtaggtacg tccacaatga
    35041 cttcagctgt taatgtcatg gttcgtttcc tccttttttt gtcttttctt atcaagcgac
    35101 aaaaagttcc ttgcctattt tactagagat cgatggattt gtcttatctt ctgccaaatc
    35161 ctaacaaaaa attaacagca gataagaaaa aaaagaactg tgtcaaaaag ttcagacaca
    35221 gccttttcta ccagacaata agtggcgaat gtttgaaaag gaaacagctg ggtttgcttt
    35281 tctttttaga tgttcgctct atttttcttt attacatttt ttgctcttca cggatacgtg
    35341 attccaattc gtgttgttca cgctcttttt gtgcttgacg ttcctcttct tccatcttca
    35401 aacgttcacg ttttaattca ggatgtggat cattgactac atttcctgca tcgatttctt
    35461 ctaaagcttg accgacgctt tttactgaat caaaagaatc tagagtaggc tgtgcacttg
    35521 catccaattc atgcgcgcgt ttacttgcta aaatcactag agaatatttt gaatttacac
    35581 gatctaatag tgagtcaatt gaaggtttta acatcataag actacatctc ctttaacatt
    35641 ttaatatatt taccgattac gcgatctact cgaaaatgtt cactggcaat aatgtttttg
    35701 attcgttcaa ctgctagcgg cacttcatca tttacaacag catagtcgta aagagccatc
    35761 atttcgattt cttcttttgc aactttcatt cgtttttcga ttacttcatc tgcatctgtt
    35821 cctcggccta cgatccgtga ttttaattcc gctaaatctg gcggagtcaa aaagatgaat
    35881 acaccatcgg gcactttttc tttgacttgt tttgctcctt ggacttcaat ctccaagaaa
    35941 acatcttttc cttcatccaa tgtcttgttg acatatgaca aaggagttcc ataataattc
    36001 ccgacatatt ctgcgtattc cagcatctct ccagcttcga tcattgattc aaactcttct
    36061 ttgcttcgga agaaataatc aacgccttcg acctcccctt cacgcatttt acgggtagtc
    36121 attgagatcg aatactgaaa atcattatcc tcactctcaa aaattgcttt tcgtactgtg
    36181 ccttttccta caccggatgg accagacaac acgattaata atccacgctc tgacatgacg
    36241 acgtcctttc aactagtctt tttgtactta tcgtttattt tgcacttttt ttctgcaact
    36301 ttcaaggtta tctttaatta tagctagaaa ttggtaaaaa agctaccctg taccaagagg
    36361 tcgtaaaaaa gctgtcctgc atcaagtaat aagaacagcc aaacataaac agcttctcat
    36421 gtttttcgtt tggttggggt tattatcgca gatgcaagct tttgaacgcc gtgtataaga
    36481 ggtcgtgaag aagccgatta gtttcgagta tgaagaaaaa ttttgtgaaa atagtttctc
    36541 acatttttgc ataaatttgg cttaataccg agaaaatggt ttttgaacat cacttattca
    36601 aaataaaaaa agattgtgac acgaattttg tcacaacctt taaatgtatt cctagagcaa
    36661 agaagctaag cgaagaaatc caattctgtt tatttattgt atttctttgt tcagcatcct
    36721 tgctaaaagc ccatattgga caaagtattc actacaccca tgatctcatc ttttcgagaa
    36781 cgtgcttttt ctgtcggatc ttctacctct tctgtgtcaa ttcgaacaat aaatttccga
    36841 ttcatcgtca cgtaagcacc gtcgttgatc aaaataaaca gttcgttctc attatagtct
    36901 gcacaggcat ctttccatac gtcaaagccg tttttttcag aagggatatc ccgtttaacc
    36961 acagtttttc cacttaattc gtggaacgtt acgtcataat atttcattat ctctacctct
    37021 ttcgtcattc aatattttgt acttgttctc tgattttttc taagatcgtc ttagactgga
    37081 cgacttgatt tttaatttcg attgcatttg atttggaacc gatcgtgttg atttcccgat
    37141 tcatttcttg gatcaggaaa tctaattccc gacctacagg acattgtgct tcgataagtt
    37201 catctagttt ttgtacatgg atcgccagac gatccagttc ctcgtgaata tctccgcgtt
    37261 ccaacaagat ggctagctcc gtcaacaacc gttgctcatc gactttcgct ccaagaaatt
    37321 cctccagctt tttttgatac cttatttgaa attccttttc atagatttct acaaaactat
    37381 cgagtttttt tagtacttct ttgaattctt cagtattctt tttcaacact aaagctaaag
    37441 cttgaccttc tttttctcga ctcgcctcaa tagaatcaag tgcgcttttc aatgtatcta
    37501 gagctaactg tgccaattct tccatgctct cttccggttt ttcttctacc gttacgaagt
    37561 tttcgtccag cacgaagcgt tccgccatcc gactaattga cacttgattt tgactaccgt
    37621 atcgttgttg aattccgtct gtcaattgag tgataagtga atcaatcaat tcccagttga
    37681 tgacgatctg tttttcgttt ttgccaatat aagctagatt cacaaatact tcgattcgac
    37741 cgcggcttaa ctgctgttta ataagctgac gaaaatcgtt ttcaacaaag ttcaggattt
    37801 taggacttcg tatttgaaca tctagaaaac gctggttgac actttttatt tcaatatcta
    37861 actgatacgc ttttgtttcg cggatggctt tgccaaaacc agtcatactt ttcattcgac
    37921 agggtccttc ctcattacat attttctatt gctttttgca gttgttcaaa ctcttcgttc
    37981 gtcaatgtca ggcctttccc cattttttca tggtctggcg cccaatctcg aagatcgaat
    38041 tttggcgggc gaccattcca gctgactagg ttcagttctt tacgccaccc cttgttgttt
    38101 tctgacaata tagcgatttc ttctacgatt tcatatgaaa attcttgtgc catggttgtt
    38161 cctccttgag ataatataaa tataggatca gtaatgtgtc aactggttgc ttaagcaatt
    38221 catgctgcaa acgatccttg cgttttcctt gtagcagata atcaaaataa acagttttcg
    38281 tgcgctcatt ttgtattttt tgctggtatt ttcgatacct tcgccattct tcagtactta
    38341 attgaccaat ttgtgccaat aaatcatccg gcatactttt tatatcttgt tggcagatca
    38401 tttgaatcat catgtctact tgatagattt cattgggcag taaaaaatgt ttttttgcta
    38461 aaagttctag catcgccaat ccgcatgtct ctggtacgac cctgttctta tataaattac
    38521 gcagtttttg ccaaaatttt atgcttttga aaaaagataa ttctaactga atttcttttg
    38581 ttaagtaaga caaaaatcct cgccagtatg ttcttgcagg tttaacagaa tgaaatgtat
    38641 accagttccc atagtaatag cctaatcgtt ttttcatttc cagatagcct aattgtaaat
    38701 ttaattggtt cctttggcta tcaaaaagca gaaagctgcc tagtgtccac aatgtttgac
    38761 atttccaatg gataaaaatg tctggcatac gaattttttt cgctgggcct ggcccttgca
    38821 catctacgac aaatgcctct gttgctcctt tgttaatcgc aatatcaata ggtattttgt
    38881 tgcgataccc accgtctgca tatttatttt ttccgatctt tcgataagcc atagcgggat
    38941 aaaatgaagc agaggcgagt atccaatctg gtatttcttc tgtttttgtc tgttggatat
    39001 cagtcactac ttccgctagt tctggcagtt tagtagacac cgtatataaa cgtattttgg
    39061 gattatgttt gagtaaggac aaatccaaat tgtctttgac catcttttcc aatggagcag
    39121 aagaaacccc gccttcaatt agtgctgttt tcgtcatttg gcgtctttct cgatagaagc
    39181 gttcacgaag gtcttcaact gcagccattt ctggtaacgc aagcacttgt cttgtcgaca
    39241 gctttttcca taaattcaca gcttttttca tatctccttg taaaatcaat gcgccgttca
    39301 acgcacctac cgaggtacct gtgataatct caaagttgat atcatgttcc ttcagcgcct
    39361 gccacacacc aatctgataa gcaccgtgcg ctcctcctcc acctaaaaca agtgctgtat
    39421 gatagaccag ctttttattt aattgtgtgg ttccttgata gccgttttta tgaaaaatac
    39481 gcaaccattc ttctgataga ggagattgaa ataaaaaaca acagttttct ttaataaaaa
    39541 aacgagcgca agcttccata taccgaaaaa attttttcca ttcaaaagtt tcaccttcaa
    39601 tcaacagatt attaaaaata acatctcctc tacttttagc aatagtaaaa tagacggtat
    39661 attttttcga tactgcttta aaagcacatt gcttttttgc agaacgccaa aaagcgtctc
    39721 tactttcttg atgactttga aaaaatggaa ggggttgttt tgcttgctgg ataggcgaat
    39781 acagcgacat tttctgtgaa aagtaaactt tttttatctc catcgcgctc tcctttttct
    39841 tcaagtatac cagtacgtca taaaaaggtc atgagtctcg tattcgactt tgtagattcc
    39901 ataagaaaac aattcataaa acctccttta aataaaaaaa tacaaaaatc acaaaaatta
    39961 attgaaaatg agagtgtttt caatgaaaac gtgattttgt aatggaattt taaaataaaa
    40021 gaaacaagct tttttaatgc aaatgttgta aaataaaaga gattaagagg aaataagagg
    40081 aggaacatga tgactgagtc agtttatgta catattgata ccacaagtaa tgctgtttta
    40141 acaaaagggc tgactgctac tgactttgca aacagtatcg tgcattttcc tcaaaacttg
    40201 ctcttgcttg atccatctgc ttctgctgga gaatatgaat cccatacagg gctgaaagta
    40261 atccgtggta cagaaaatat tcagcgtttc ttttcctctt ctcgtaacag gcgtggattc
    40321 gatgaattga agtggatcga ctttactgat ttaacgatgc tgaaagaatt gacaccttta
    40381 gaaatttcag aattattata ttttggtcat atgaaaacac atcttcattc gccgtttttt
    40441 tataaactac agaataattt tgtatacttc gatcttaatg atcagctgaa tcggatttat
    40501 tatcgctatt tagatgaatt ttataggatt tttgctagta aattaagttc gatcttgtca
    40561 gataagatca atgtaaaaaa atcttttttc aaaaaagaaa cacctgttga aaaaatcagt
    40621 gtggaattat tgaaagaaat gcgtaatttg atgcaggaag ggatcatttt ttcttttgat
    40681 caagttggtt tgatcgatgg taaatatcgt atcccaatct atgtgattga agattatatt
    40741 tggaaattaa aaggcacccg gtatcgagaa gaggaaatca tcgctacttt aatctactct
    40801 gtcaccgatc gacactggca attggtagaa gatgccgatc tttcttatct gccattgaag
    40861 tagatctatt tcttatcaaa aaataaaaag gaaacaagaa actaggacat gattctgtct
    40921 caagtttctt gcttcttttt tatttacagc tcctgtcgtt tatctggcac aaaaatcgaa
    40981 ggagtcgttt gttggatccc taataaaacg atgatcgtta caatagctgt actcaacccg
    41041 ctggcaccat tcattacgaa agaaaagagc caaggattca tcccccatag tgcatacgct
    41101 ccccagaaaa ccactcctgc aataaaatgc caaaaatatc tggaaagtgc gccaatcaat
    41161 gcaccaaaca cgatgctttt tctaatttgt ttcgtattat cgtctacata gcctttttgg
    41221 acatttgaag ccatgagccc tgctgcgcct gcaaaagtat aggcaatcgg gtactcaatc
    41281 aacacttgaa cgacacttaa ataataaact tgtcccaacg gaaaatgtag gatgccccaa
    41341 atgaaacctg ccagcatccc tgcctttgtc cctcttctta acgcaaaaag agtcaatgga
    41401 atctgcccta atgaaataga aaaactgctg ccgatctgga tcggaatcaa cgacaacacc
    41461 atcgctaacg ctgcaacaat cgttccttct acccaaactc tattttttcc cataaaaaaa
    41521 cttcctcctt tgaataaaaa agtc
//
LOCUS       DAPBAF010000024        41075 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.024, whole genome shotgun sequence.
ACCESSION   DAPBAF010000024 DAPBAF010000000
VERSION     DAPBAF010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 41075)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41075)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41075
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.024"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(52..663)
                     /gene="rpsD"
                     /locus_tag="RD451_001468"
     CDS             complement(52..663)
                     /gene="rpsD"
                     /locus_tag="RD451_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HDT7566736.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            925..1776
                     /locus_tag="RD451_001469"
     CDS             925..1776
                     /locus_tag="RD451_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HDT7566737.1"
                     /translation="MRGYVQMEKSEGSLRRKSMNPVSPLFEKIDASIEKKANLFENSF
                     SRYAVRAVLACLFLTLGTAVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAEL
                     GTSNMLYMTVGVFRQRLALSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNF
                     MLESIAVKLAKPSATILVEGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLG
                     YEHVIANFPAFTLTYFASHGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQ
                     SKSSYVD"
     gene            1804..2439
                     /locus_tag="RD451_001470"
     CDS             1804..2439
                     /locus_tag="RD451_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HDT7566738.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            2459..3232
                     /locus_tag="RD451_001471"
     CDS             2459..3232
                     /locus_tag="RD451_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDT7566739.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            3640..4437
                     /locus_tag="RD451_001472"
     CDS             3640..4437
                     /locus_tag="RD451_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HDT7566740.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            4415..4828
                     /locus_tag="RD451_001473"
     CDS             4415..4828
                     /locus_tag="RD451_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HDT7566741.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            4812..7457
                     /gene="mutS"
                     /locus_tag="RD451_001474"
     CDS             4812..7457
                     /gene="mutS"
                     /locus_tag="RD451_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HDT7566742.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            7475..9583
                     /gene="mutL"
                     /locus_tag="RD451_001475"
     CDS             7475..9583
                     /gene="mutL"
                     /locus_tag="RD451_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HDT7566743.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRETGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            9605..10165
                     /gene="maf"
                     /locus_tag="RD451_001476"
     CDS             9605..10165
                     /gene="maf"
                     /locus_tag="RD451_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HDT7566744.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(10250..12238)
                     /gene="treP"
                     /locus_tag="RD451_001477"
     CDS             complement(10250..12238)
                     /gene="treP"
                     /locus_tag="RD451_001477"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HDT7566745.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            12461..13174
                     /gene="treR"
                     /locus_tag="RD451_001478"
     CDS             12461..13174
                     /gene="treR"
                     /locus_tag="RD451_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HDT7566746.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            13251..13697
                     /gene="msrB"
                     /locus_tag="RD451_001479"
     CDS             13251..13697
                     /gene="msrB"
                     /locus_tag="RD451_001479"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HDT7566747.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            13867..14469
                     /gene="ruvA"
                     /locus_tag="RD451_001480"
     CDS             13867..14469
                     /gene="ruvA"
                     /locus_tag="RD451_001480"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HDT7566748.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            14482..15483
                     /gene="ruvB"
                     /locus_tag="RD451_001481"
     CDS             14482..15483
                     /gene="ruvB"
                     /locus_tag="RD451_001481"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HDT7566749.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            15512..16090
                     /locus_tag="RD451_001482"
     CDS             15512..16090
                     /locus_tag="RD451_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDT7566750.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            16142..16624
                     /locus_tag="RD451_001483"
     CDS             16142..16624
                     /locus_tag="RD451_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HDT7566751.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            16741..17115
                     /locus_tag="RD451_001484"
     CDS             16741..17115
                     /locus_tag="RD451_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566752.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
     gene            complement(17793..19145)
                     /gene="brnQ"
                     /locus_tag="RD451_001485"
     CDS             complement(17793..19145)
                     /gene="brnQ"
                     /locus_tag="RD451_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HDT7566753.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
     gene            19292..19882
                     /locus_tag="RD451_001486"
     CDS             19292..19882
                     /locus_tag="RD451_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HDT7566754.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVLVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            complement(20010..21359)
                     /locus_tag="RD451_001487"
     CDS             complement(20010..21359)
                     /locus_tag="RD451_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDT7566755.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(21527..22267)
                     /locus_tag="RD451_001488"
     CDS             complement(21527..22267)
                     /locus_tag="RD451_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HDT7566756.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
     gene            complement(22280..23872)
                     /locus_tag="RD451_001489"
     CDS             complement(22280..23872)
                     /locus_tag="RD451_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327538.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HDT7566757.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            complement(24440..24736)
                     /locus_tag="RD451_001490"
     CDS             complement(24440..24736)
                     /locus_tag="RD451_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566758.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     gene            24912..25637
                     /locus_tag="RD451_001491"
     CDS             24912..25637
                     /locus_tag="RD451_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HDT7566759.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEMAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            25630..26472
                     /locus_tag="RD451_001492"
     CDS             25630..26472
                     /locus_tag="RD451_001492"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HDT7566760.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELIALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            26475..26996
                     /locus_tag="RD451_001493"
     CDS             26475..26996
                     /locus_tag="RD451_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HDT7566761.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(27249..27812)
                     /locus_tag="RD451_001494"
     CDS             complement(27249..27812)
                     /locus_tag="RD451_001494"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HDT7566762.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            28063..28332
                     /gene="rpsO"
                     /locus_tag="RD451_001495"
     CDS             28063..28332
                     /gene="rpsO"
                     /locus_tag="RD451_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HDT7566763.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            28520..30646
                     /gene="pnp"
                     /locus_tag="RD451_001496"
     CDS             28520..30646
                     /gene="pnp"
                     /locus_tag="RD451_001496"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HDT7566764.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            31156..31422
                     /locus_tag="RD451_001497"
     CDS             31156..31422
                     /locus_tag="RD451_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HDT7566765.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            31599..33557
                     /locus_tag="RD451_001498"
     CDS             31599..33557
                     /locus_tag="RD451_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HDT7566766.1"
                     /translation="MTGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGLSGINPDFVIGS
                     VSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLIIPAMIGGAALLA
                     DGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFMVQRFGTDIVGK
                     AFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKLGLFILGNIFLA
                     TTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQNPEAQQIKNLNP
                     FFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPRLKIMYPGNSIG
                     QMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALLYFYLIQNGHSR
                     WLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWEQGNIIRESSTE
                     DVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSILDKRPKRARVY
                     WFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQVIHDLMKQGRL
                     PKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAIKKIATSPETWF
                     GLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            33911..35212
                     /locus_tag="RD451_001499"
     CDS             33911..35212
                     /locus_tag="RD451_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HDT7566767.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYYYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKTE"
     gene            complement(35342..36712)
                     /locus_tag="RD451_001500"
     CDS             complement(35342..36712)
                     /locus_tag="RD451_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDT7566768.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(36894..37217)
                     /locus_tag="RD451_001501"
     CDS             complement(36894..37217)
                     /locus_tag="RD451_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HDT7566769.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            complement(37542..38150)
                     /locus_tag="RD451_001502"
     CDS             complement(37542..38150)
                     /locus_tag="RD451_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HDT7566770.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEEESTGEGGEPEVIGSTEE"
     gene            38480..39196
                     /locus_tag="RD451_001503"
     CDS             38480..39196
                     /locus_tag="RD451_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HDT7566771.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            39209..39904
                     /locus_tag="RD451_001504"
     CDS             39209..39904
                     /locus_tag="RD451_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HDT7566772.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            39988..40617
                     /gene="udk"
                     /locus_tag="RD451_001505"
     CDS             39988..40617
                     /gene="udk"
                     /locus_tag="RD451_001505"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HDT7566773.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
BASE COUNT        13393 a         7618 c         8582 g        11482 t
ORIGIN      
        1 aaagaccagc tatccaatag atagcggtct ttttcaagaa agcttttgaa attataagct
       61 ttggttgtag tattcaacga caagagcttc gtcgatttct ggatatagtt cgtcacgttc
      121 tggtaaacga gtcaatgaac cttccaattt ttcagcgtca aagcttacga atgctgggcg
      181 tccaacagtt gcttctacag cttcttttac tgttacgatg ttttgtgatt tttcacgaac
      241 tgagatcact tgacccactt ctacgtggta tgaagggata tcaacgcgtt tgccatcaac
      301 taaaatgtga ccatggttaa ctaattgacg tgcttgacga cgagtcgttg caagtcctaa
      361 acggtaaaca acattgtcta aacgttgttc tagtaagatc atgaagttaa caccatgttt
      421 accttctttg attttgctag cttttacgaa caagttacgg aattgacgtt cgttcattcc
      481 gtacatgtga cgaagttttt gtttttcagt taattgcatg ccgtattctg attgtttgcc
      541 acggctatta ggtccatgtt gacctggtgc gtaagggcga cgtgctaatt cttttcctgt
      601 gcctgacaat gagatgccta agcgacgaga aattttccat gatggtcctg tataacgaga
      661 cattaaaatt tcctccaatg aatataagtt tttggagtaa aataatccgt tgaaaaattc
      721 ataatcatat agtttgttct tcaatcttca cctttgcagc cgcggttaca caatcgaacc
      781 cgagacgggg caacaaacta gggatgagtt attatttttc tgctgcatta ttttacacaa
      841 attacagtat atgatagatc atccacgaat gtcaagataa ttagtacata aaaacgcttt
      901 acaaacctag gctgtcttta taaaatgaga gggtatgtgc aaatggaaaa aagcgaagga
      961 agtttaagga gaaaatcaat gaatccggta tcaccattat ttgagaaaat cgatgcttca
     1021 attgaaaaga aggcgaatct ttttgaaaac agcttttcac gttacgctgt tcgagcggtt
     1081 ctcgcctgtt tgtttttgac tttaggaacg gctgtggcat ttgcgatcgc gatgaagggg
     1141 gaagatatcg cgcatggtct aggaaagatt ttatacgcat ttatgttcag ctggggtctg
     1201 gtcatgattc tatacatgaa cgccgaatta ggaacatcga atatgcttta tatgaccgtg
     1261 ggtgtttttc ggcagagact tgctttaagt aaggcagcca agattctatt tgcctgtatt
     1321 tttttcaata tgattggcgg tatattatgt ggatttctaa tttctatgac tacgccattt
     1381 caagatttaa cgttggacaa ctttatgtta gaatcaatag cagtaaaact agcaaaacct
     1441 tcagcaacga ttttggtgga agggatgttt gcgaatatcg ttgtcaatac cgctgtactg
     1501 atcagcatgc ggatgaaaga ggatgtcgga aaagtgatca cagtcgtatt catcattttc
     1561 atttttgctt ttttaggata tgaacacgtg atagcgaatt ttcctgcctt tacgcttact
     1621 tactttgctt ctcacggaca gatggatgga atgacagtca gcaatgtgtt acataatttg
     1681 ttttttgctt tggcaggaaa ttatattggt ggcggtttag taatgggact gggatatgct
     1741 tggctgaatc agtcaaaatc atcctatgtg gactaaaaag tcgttcatta aaggggaagt
     1801 gccatggaag ttttagtttt tccaaaaaat gaggaaaaag cgttacaaat ggaaaagtac
     1861 atgaaaaatc ttttttcctt tgctggagta cctaagccgg aacgcgctct tttacaacaa
     1921 ccgttactgg atgagagcaa aaatttatct atttctgaag ttttagcttt tgttcattat
     1981 tattatgaac aaatcgaaag agagtatcag tatgtagcga tcgatttagt ccagaaaaac
     2041 atcaaacggc ttacatttga agacttagtc gtattgttgc cactagttca gaaaaaagaa
     2101 tggtgggaca gcatcgactc ttggagaaaa gtatacagca catggtgtaa agcctaccca
     2161 gagcagcgtg aagaagtctt tcaattgttt gaaaaaaagg aagatttttg gctacgtcga
     2221 atagcaatca cgttgcaatt aggttataaa cagcaaacag acacaggact attgatccga
     2281 gcaatagacg aagatcgtca aacaaaggaa ttctttatcc aaaaagcaat tggttgggca
     2341 ttacgcgatt atagtaagac cgatgccgat tgggtaaaaa gacagctgac aacagatttg
     2401 agtaagttag ctgttcgaga ggcaagtaag tatttataag aaagcgagac gacaagagat
     2461 gagacgcaaa ttatttgctt ttgatattga tggaacgttg ttagattcaa acaaacaagc
     2521 tttagatagc acaagagaag cattggaaaa attacgcaaa gccggtcatc tggtcacgat
     2581 tgctacaggg cggagccgat ttcatgcgca agagatcatt cgcgatcttg attttacgaa
     2641 ctacatttta tgtaatggag cggccggttt tttagaccat gaacaagtat ataagaattt
     2701 actagatcgc gaccagttgg atgcgttcgt tcaagaagcg catcatgagc agatcgatac
     2761 agcttttgtc agcttagaca atatcaagcg ttcttcttcc aatgatgtaa cggtgatgga
     2821 agaagcgatg cattctttcg gtgctgtctt gcctgaatta gatcagtttt ttgcagagga
     2881 acaagaaata taccaagcgt tagcattttt cgatcaaaca tatgatggga agttctcttc
     2941 atatgataaa attcgatttg tccgctggca tgagaacagt gtagatgtcg tacctaaaaa
     3001 tggttctaaa gcagcgacaa ttctgcactt agcagaacaa gtaggcatcc ctcatgaaga
     3061 catcatcagc tttggcgatg gacaaaacga ccgtgaaatg ttgcgcatgt caggaattgg
     3121 gatagctatg gggaatgctg tgccagaagt acaagcagaa gctaagatgg tcactgatac
     3181 aaacgatcag gatggaattt ggaaggcatt gaaagagtta agcgtgattt aaaagaggtt
     3241 gtgaaaaagc tgttctgcat caagtaataa gcccagccaa acaaaaatag ctcctcctat
     3301 ttttcgtttt tctgggctta ttaccgcaga tgcaagcttt cgaacaccgt ttaaggaaga
     3361 ggtcgtgaca gaagtggtca gtttcaagaa ataagaaggg atttacgaaa attgcttctc
     3421 aaatttttgt aaaattacgg cttatttctg aagaagtaga tgaaacaacg tttattcggg
     3481 aaatgggact gtgacaagat gtttgtcata gtcccatttt tttattttat ttttcaaaac
     3541 taagaaatac caggaaagag ttccttttgt ttgacctttt ctttcttatt gaaaacaact
     3601 ataatataga gtgatgttaa aagagaagag gaatttagtg tgcgggtatt gtttattggt
     3661 gatgtagtag gttcaatggg acgagagatg attactgaat atcttcctag attgaagaag
     3721 aagtaccgtc cgcaagtaac gattgtaaat ggtgagaatg ccgcttctgg acgtggaatc
     3781 acagaaaaaa tctataaaaa atttttgcaa gacggcgtag atgtcgtgac gatggggaat
     3841 catacgtggg acaaccgcgg aatctttgag tttgtaaatg aagctaaaaa gatggttcgt
     3901 ccggcaaatt ttccggaagg gacgcctgga caagggatgg tctttgtcaa agtgaaccaa
     3961 gtcgaactgg cagtgatcaa catgcaggct cgttctttta tggtggactt ggatgatcct
     4021 tttcgtaaaa tgaatgagct ggtagaagaa gccagaaaac gtacgccgat catttttgta
     4081 gattttcatg gagaaacaac aagtgaaaaa caagcaatgg gctggttttt agatgggaaa
     4141 gtttcagcag tggtcggtac acatacacac gttcagacaa atgatgcgcg aattttgcca
     4201 agaggaacag cgtatctgac agacgttggg atgacaggtc cctatgatgg tattttgggt
     4261 atgcgcagag aacctgtaat cgaaaagttt ctgactgcat taccaaaacg ttttgaagtt
     4321 gtggaacaag gccgatcgat tttaagcggc tgtatcttgg aattggatga tacgacaggt
     4381 catgcaaaag aaatccagct gattcagatc aacgatgatc gaccgttcat ggagtagaaa
     4441 gagaggcagt tttttgcagc aggagccgga aattcaaaaa gaagtaagga aactgacaaa
     4501 acttttaaga gagaatgaaa cgatcattcg ctacaaagaa cttgaagaaa agatccagca
     4561 aaaccagtat ttagctgagt tgagagaaaa aatcaaacaa gcgcaaaaag atgctgttca
     4621 ttttgcccac tatgacaaac cagcagcaga aaaagaagca atcaaacaag cggatcaatt
     4681 catgcaagaa tttgatcagc atccgcttgt tgtagcttat agaaaacagc tgttggaagc
     4741 agatgatctg cttcatcatt taacaactat gatacaagaa gaaatcaatg gacaaataga
     4801 ggaggaaaaa catgcctcaa aaaactaaaa atactcctat gatggaacaa tatctaagca
     4861 tcaaggccca ataccaagat gcttttttgt tctatcgttt aggagacttt tatgaactat
     4921 tttacgaaga tgcgatcaaa gcgtcacagc ttttggaatt aacgttgacg agcagaaatc
     4981 gaaatgcaga agaacctatt cctatgtgcg gtgtacctca ccatgcagca caaggatata
     5041 tcgatgcctt gattgaaaaa ggctataaag tagcgatttg cgagcaggta gaagatccaa
     5101 agacgactaa agggatggtc aagcgcgaag tgatccagct agtcactcct ggtacagtca
     5161 tggacagcaa aggattgtcg gcaaaagaca acaatttttt aacagctgta gttagtcaag
     5221 gaaatgaatt tggctttgct tatgccgatt taagtacggg agaattgaag acggctcggt
     5281 tgcatgatga agaagctgtt ttaaatgaag cctctgcatt gcagacaaaa gaactcgtat
     5341 taggcagtga gatcactgat acccttcgtg aacagctaag cgggcgttta gggctagtct
     5401 tttctcaaca aaatgagatg gaagaaaacg cggaatttag ctttttgaca agcgaactag
     5461 tcgatccgct ggaaaaagaa gcaaccggca aactattgac ttatttatcg gtgacacaaa
     5521 agcggagttt agctcatatc caaaaagcag tagaatacca accagatcat tttttgaaaa
     5581 tggattatta ttcaaaattc aacctagaat taagccaatc tattcggact gggaaaaagc
     5641 acggcactct tctatggttg ttagatgaaa caaaaacagc aatgggtggc cgtttactaa
     5701 aacaatggct agaccgtccg cttatccagg caaaacaaat taaagcaaga caagaaatgg
     5761 tcgcttcttt gctagacagc tattttgaac gtatcgattt gcagtcagca ttaacgaaag
     5821 tctatgatct ggaacgccta gcaggtcgag tagctttcgg taatgtcaat gggcgagact
     5881 tgatccagct gaaaacttct ttagaacaag tgccaatgat cagagggttg attgaaggaa
     5941 tcgatcaagg tcaatggcaa agtctgcttt cagaaatgca gccgatggac catctcgtcc
     6001 aattgatcga ccaagctatc caagatgatc cgccgttaca aataacggaa ggaaacatca
     6061 tcaaagatgg attcaatgag cagctcgata tgtaccgttc tgctatgaga aacggaaaga
     6121 aatggttggc agaacttgaa gcaaaagagc gtcaagaaac aggaatcaag aacttaaaaa
     6181 tcggatttaa ccgcgttttc ggttattata tagaaattac aaaagcaaat cttggaaatg
     6241 cagaactgga gaagtatgaa cgaaaacaaa ctttagcaaa tgcagagcgt ttcatcacac
     6301 cagaactaaa agaattggag acacaaatcc tcgaagcaga agaaaaatct gttgatttag
     6361 aatatcagtt gtttttagct gtgagagaag aagtcaaaaa ggctatccag ccgctacaag
     6421 tacttgcaaa agcaatcagt gcagtagatg tgctacaaag ttttgcaacg atcagcgaac
     6481 gctatcagta tgttcggcca gaacttgtca gtgacaagca tcagcttctg atcaaagacg
     6541 gacgacatcc tgtagtagaa aaagtattag gacatcagga atatatccct aacagcgtag
     6601 aaatggcaga agacgaaatg atcttgctga ttacaggacc gaatatgtct ggtaaaagta
     6661 cgtatatgcg acagttggca ttaactgttc tgatggcgca aatgggctgt ttcgttccgg
     6721 caaaacaagc agttttacct atttttgatc ggatttttac ccgaattggt gcaagtgacg
     6781 acttaattgc tggacaaagt acttttatgg tagagatgat ggaagccaat caagccctgc
     6841 gttatgctac gccaaacagt ttgattttgt ttgacgaact agggcgagga acagcaacct
     6901 atgacggaat ggcgttggcc caagcaatca tcgaatatat ccatcgtcat gtacaagcaa
     6961 aaacactctt ttctactcat tatcatgaac tgacggtact tgagaaagaa cttccgcagc
     7021 ttaaaaatgt ccatgttgga gccgttgaaa aagacggaga agttgtcttc ttgcataaaa
     7081 tgatggatgg acctgcggat aaaagctacg gcatacatgt ggcaaagatc gcaggattgc
     7141 cttccaatct actagaacga gcagcagata tcctgcatac gctagaaaat ggcgataacg
     7201 gacaccatac tgttccagct gaagtagaag agaaaactaa aacagccaaa caggagcaaa
     7261 taaaaccacc tgcagaaaaa gtaaatcaag accatataca agaccgtgta aaagaagaaa
     7321 accaacagct ttctttattc agtgaattat ccgaaaatga aacagaagtc attgaatcac
     7381 tgaagcaaat aaatttacta gaaatgacgc caatggatgc actaaacaca ttatatgaat
     7441 tacaaaaaca actgtaggaa gaaggcggat atcgatggcc aaaatccaag aattatctga
     7501 acgtttagct aatcagatcg ctgcgggaga agtagtggag cgaccagctt ccgttgtgaa
     7561 agaattagtg gaaaatgcaa ttgacgccgg cagtactcag attgatatct tagttgaaga
     7621 agcgggactg cggacgatcc aagtgattga taacggagaa ggcattttgg cagacgacgt
     7681 agagaatgcc ttcaagcggc atgcgacaag taagatccat aatcgcgacg atctttttcg
     7741 catacgaacg ctgggctttc gaggggaagc tttgccaagt attgcctctg tttctgaaat
     7801 gactctggaa acggcgaatc aggaagaaaa acaaggcacc tatctgtcgc tgaaaggcgg
     7861 agaagttatt gagcatcgac cagcaccact gcgtcaagga acgaagatta ccgtcagcaa
     7921 tctgtttttc aatacgccag cccgcttgaa atacgtgaaa acactgcaca cagaattagc
     7981 gaacatcggg gacatcgtca atcgactggc attgagtcat ccatcgattg cttttcgttt
     8041 agtacatgat ggaaacaaaa tgctggcaac tgctggaaat ggcgatctga aacaaacaat
     8101 tgcgggaatc tacggattat ctaccgcaaa aaaaatgctg aaaatcgaag gaaaagatct
     8161 agattttgag ttatttggct atgtttcatt gcctgaggtg actcgtgcca gtaggaatta
     8221 cttatcgacg atcatcaatg gacgttttat caagaacttt tccttgaata aagcaatcgt
     8281 tgcaggttat gggtcaaaat taatggtcgg tcgtttccct attgctgtat tggaaatcaa
     8341 aatggacccg cttttagtag atgtaaatgt tcatccgacg aagcaggaag tccggctgtc
     8401 gaaggaaaaa gaactaacag agctaattag taacgccatt caaaaagcat tgtctcaaga
     8461 aaatctgatt ccaagtgcag cggataatct acggtttaag aaaaaagtac ctgatcagcc
     8521 taaaacagaa caaatcgaaa tcgatttgtc ctacgctttt gaagaagaaa aacctaaaaa
     8581 gccaagtagt ttgaattttg atcgagagac aggtaccttt ttcgtagaag aactaaagaa
     8641 cacatttgtt gacagaattg ttgataagtc tgtggaaaat gttgaaaact attctggttt
     8701 ttctgaagaa aacaccactt atccagaaaa aacagcgaaa acggtggata agtttggtga
     8761 aaatgttgat aactttgtag aaaaaacagt ggaaaaatct gaaaagaaag aatttcccat
     8821 tgtggataac atggagaaaa caaatgaaga acaagcagat aaatccgtag aagaggatga
     8881 aaagatttac gaggaagaat tgacactcca tcctgaattt gatttcactc aaggaaacga
     8941 caaaacatta gaacaagcca tcaagaaatt agaaacggaa aaaccagtac aacgttttcc
     9001 tcagttggaa tattttggac agatgcacgg aacgtatctt tttgcccaaa gtagcgatgg
     9061 gttgtacatc attgatcagc atgctgccca agagcgcatt aagtatgaat atttccggga
     9121 aaaaattggg gaagtatctg atgatctgca agaattgctt gttccatttg tgttagacta
     9181 tccaaacagt gatgctttga aattaaaaga gcaaaaacac ttgctagaag atgcagggat
     9241 ttatttagaa gaatttggtc aaaacagctt tattgtacgg gcccatccta cttggtatcc
     9301 caatggagaa gaagaatcga ttattcggga gatgatcgat atgctgctga caactggaag
     9361 tgtgagtgta aaaaaattcc gtgaagcaac agcaatcatg atgagttgca aacgatcgat
     9421 taaagccaac cattatttga atgaagcaca agcacgtgtg ctgctgaagg atctggcacg
     9481 atgcgaaaat cctttcaatt gtccccatgg ccgtccagta ttgattcact ttaccaattc
     9541 ggatatggaa aggatgttca aacgaatcca agacccgcat taagtcaaag agaagaggga
     9601 aaacatgaag attgtattag catcccaatc accaagaaga aaagagttat tggctcatat
     9661 cgtttcagaa ttcgagattg aacctgctga tatcgatgaa acgccatttc cagacgaaca
     9721 gcccgtcgat tatgttcgta gaatggctga agaaaaagca cgaactgtct gggaacaaga
     9781 tgaaaaagaa gaccatttag tgattgccag tgacacgact gttgttctca atcaagagat
     9841 catgggtaaa ccagaagatc tggctgaggc tgaattcatg ctgaaaaaac taagcgggga
     9901 aacacatact gtatatacag ctgttgtttt aaaaacaaag gaacgagaag aacggatact
     9961 agcagaagca catgtcactt tttatccttt gacagacgaa gagatcaaac gctacttgga
    10021 gacgggggat tatgcggata aggcaggggc atacggcatc caaaatgctg cgagtgtatt
    10081 cgtcaaagaa atttctggag attattacag tatcgtagga tttccgattg gtgctgtcaa
    10141 tcaggcactg aaaacattca tttaaacaaa aaagcggact atctgatttt cgattgaaaa
    10201 tccatgatag cccgtttttt ttattgaaaa gattacttat ctactctgac taagatttta
    10261 cttcagcttt accgactgct tcgcccgggc gaacaagtcc tgattggtca agagaaagtc
    10321 ctgcaacttt ttcattattg gtcaaagcaa caataatgtc agttttcttg ccagcttgtt
    10381 ctatttctgg caaatccatt tcagcaatca gggtctctgg tgtgacaagg tatccttctt
    10441 tcacgaatac attgaaagga acacccttta gttcaacagt atctaatccc atgtgaacaa
    10501 gtacttccag cccctcatta gaaagaatac caatggcatg ttttgtttca aagacactcg
    10561 tcactttacc gtttactggt gcatagactt tgccgtttga cggttcgaca gcataaccgt
    10621 cacccatcat tttttgtgag aaaactgggt catttacttc agttatttcc ttgatggtcc
    10681 ctgcagcgac tgcgaataat gtttcttttg ttgcaactgc cgtaccagtt gctgaaacag
    10741 gttcgaaaga ctgtggcgtt gctgttgcgc catttgctgt ttgaagttgt acatcagcag
    10801 cattttcagg aacagcagga tcaatcttat tcaaaattcc ctgacgtcta aagatgatcg
    10861 tcaagccaaa tggaatgatg acagcaatga tcattgcgat gatgaaaggt acccatgttt
    10921 ctgcttggat agctagtatt cctggcaaac cgcctactcc gatcgcgtta gctcgaacac
    10981 ccatcaagtt agcaaacatg ccagctaatc cagagccgac cattgcagcg acgaaaggat
    11041 agacgtattt caaattgatt ccgaacatag caggttcagt tacgcctaag taacaagaaa
    11101 tcattgctgg aatcgagatt tgttcttctt ttttattccc acgatgtaag aagatgatgg
    11161 ctaagactgc agagccttgg gcgatatttg ataaagcaat catcggccat aaattcgttg
    11221 atccgaaatc tgcaatcagc tgcatatcga tggcattggt catatggtgg agaccagtaa
    11281 tcactaaagg agcatacagg aatccgaata cggcactaaa caaccagctg atagaagacg
    11341 tcaatccagt atttacgata tttgagatcc agcttccgac tgtccagccg ataggaccta
    11401 aaataacgtg tgcagctaaa acagttggta acaatgaaaa caatggaaca aaaatcatcg
    11461 agatcgactg agggatatat ttgcggaaga agatttctag atacgctaac ataaaccctg
    11521 ccagcatggc tggaataact tgcgcttgat aaccaatcat ctggacttga gcaaaaccaa
    11581 aatcccaaaa tggaatatct gctgcggctg tggaagctac actataagca tttaataatt
    11641 gcggagaaac taacgtaatt cctaaaacga ttcctaatat ttgtgtagta cccatctttt
    11701 ttgcaatact ccaagtgata cctactggaa gaaaatggaa aattgcttca ccgggtaacc
    11761 acaaaaaggc attgacacca ttccaaaact tcgagtgttc aacgattgtt ccaccaagac
    11821 tttcaaactg gataccttca agtacatttc tgaatccaag gatcaatcca ccgacaatga
    11881 ttgcaggaat cagtggtgta aagatttctg ctaaaacggc aatagcacgt tgaacgggat
    11941 gaaggttttg ttttgcagct gcttttcctt gttctttgga aaccccttca actccagata
    12001 ctgcaacgaa gtcgttataa aaagtagaaa catcgtttcc tatgatgact tggaactgtc
    12061 ctgcattcgt gaacatccct tttacgctag gtatatcttc gatcgctttt tcgtccgctt
    12121 ttcctggatc attcaggaca aaacgcatac gagtcgcaca atgactaact gcagcaatat
    12181 tttcttttcc gccgatatca tgtaacagct tctcggcatc tgcttgatat tttgccatat
    12241 caataaaccc ctttctctta acttgtctat gcaagttgtt tcttcattta ctatactttt
    12301 tttcggagag aattgcaagc gttttattaa aaagtacgag agaaaatgat atcgttttaa
    12361 aaagcttaaa ataagctttt cttaaaaata ggaacattga aatacaaaaa gagctgtagt
    12421 atagtgaaga aatgatggaa gaacgagtga gggaaaaaac atgaataagt tcaatgaaat
    12481 ttttttagat ttggaacaga aaattttagc gaaagaatat cctccgcatt cgcttttacc
    12541 cagtgagaac caattgatca aaatttatgg tgtttcacga gaaacaatta gaaaagcgct
    12601 gaatcttttg actacggaag gttatattca aaaaaaacaa ggaaaaggtt cgatcgtact
    12661 ggatcggaat cgcttcgact ttcctatttc tggattgact agctataaag agctacagga
    12721 gacccaacgt attccaagtg aaacgatcat ccatacgtta gaagaaacag aagtgacaaa
    12781 agcattgaac gagatcactg gctgggagat cggtgcgcct gtttggcatt tgatacgcga
    12841 aagaaaaatc aatggcgaag tagttatatt agacaccgat tatctattaa aggaaatcgt
    12901 tcctatttta actccagcac aagcacaagg atcgatctat gaatattttg aaaatgagct
    12961 ttctttgacg attgcttacg cgcaaaagga gatcacagta gaagaagtaa cggaaatcat
    13021 gaaaacagcg atggatcttc acgatgacac ttatgcagta gtagtcagaa gcctcgttca
    13081 tctggaagat acccgctgtt tcgagtattc tgagtcggtt caccgattag ataaattccg
    13141 tttcgttgag tttgcccgac gccgaaaagt gtaaatagtt caaaagaaag caaattgttg
    13201 gcatctgtcc actttggcgc tatgatagga tcacaaaggg ggcattttta atggataaac
    13261 caataagacc agaaaaagaa gaactgaaag aaaagttatc acccatggct tatgcagtca
    13321 cacaagaaaa tgcaacagaa cgaccattta gcgggaaata tgatgatttt tacgaaaagg
    13381 ggatctatgt agatatcgtc agcggtgaac cgttattcag ctctgcagaa aaatatgatg
    13441 caggttgtgg ctggccatca ttcagcaaac caataacgaa aagacaagtg cgcgaaaaag
    13501 ccgatttttc tcatggcatg catcgaatag aagttcgaag caaagaagca gattctcatc
    13561 tcggacatgt gtttaccgat ggaccagtag atcaaggtgg tctacgttac tgcatcaatt
    13621 ctgcctcact gaaattcatt ccatatgaaa agatggatga attaggttat ggggaattca
    13681 aatcacttgt agaataatgg aaatacacaa agagcggtac aatacgggga tttactcgat
    13741 cgtccgctct ttttttattc aagcgattgc tatttgaaag aaacgctccc tagactcctt
    13801 ttttcacaag gtgaaatgtg ctacaataaa gggaacgtat gtgtgcaaaa gaaagaggac
    13861 tagaatatgt atgaatatct gacaggtgtg gttaccttta tcaaccccta ttacatagta
    13921 gtagaaacca atggtatcgg ctaccagatc gcactaggaa atccttaccg ctacagtagc
    13981 aaactaaatc aaaaaataaa aatttatgtc catcaggtaa tacgtgaaga tgcgcatctt
    14041 ctgtatggat ttgattcgct agaagaaaag caactgtttt tgcgattagt aagtgtttca
    14101 ggaatcggtc cgaaaagtgc ccttgcaatc atggcaagcg aagaccactc cggtttgatt
    14161 caagcagtag aatccagtga tgtcacttat ttgacgaaat ttccaggagt agggaaaaag
    14221 acagcacaac aaatgatctt ggatctaaaa ggaaaattcg gtgagctgag tatcgataca
    14281 ccttttagtc tatttgatga agcaaacaca aaagacgcta cagctctatc tgaagcaatg
    14341 gaagctctct cggctcttgg ttacagtgat cgagaaatca aacgtgtaga aaaacaatta
    14401 aaagaagtag ataatcagac aacggatgag tatctacgcc aagcactcaa gctaatgatg
    14461 aaaaaataag gaggagacca aatgacagat gaatacttgt tatcaccaga atctggcgaa
    14521 aatgaactga gtttggaaaa atctcttcga ccacagctgc tttctcaata tatcggacag
    14581 agaaaagtca aacaagaact tcagatttac atcgaagctg ccagaaatcg ggaagaacct
    14641 ttagatcatg ttctgttgta cgggcctcct ggattaggaa aaacgacgat ggccatggtc
    14701 attgctaatg agatgaccgt aaatattcgt acgacgagtg gccctgctat cgaacgtccg
    14761 ggtgacttag tagcaatctt gaatgaactg gaagcagggg atgtcctgtt tatcgatgag
    14821 atccatcgat tacctagagt ggtagaagag atgctttatt cagctatgga agatttctat
    14881 gtagatatca tggtaggaca agggccaacc gcacatccgg ttcatttccc tcttcctccc
    14941 tttactttga ttggcgcgac gacacgggca ggtatgcttt ctgcaccttt acgagatcga
    15001 tttggcatca tttctcatat ggaatattat gacgaacagg atctgcagga gatcgtttta
    15061 cgttcttcgg atatttttca aacagagatc attgaagaag gggcattgga aattgctcgc
    15121 cgatcacgag gaacgcctag aatcgctaat cgcttgctca aacgggttcg tgattttgcg
    15181 caagtccaag gagacgggaa aatcgatcgt cctatagcgg atcaggcact tactttgcta
    15241 caggtcgatc aggctggatt ggattatgtt gaccagaaat tgttgcgaac aatgatcgag
    15301 ttatatggcg gcggaccagt agggttaagt acgctttcag taaacatagg agaagagcgt
    15361 gagacggtag aagatatgta tgaaccgtat ctgatccaaa aaggattttt aaagcgtaca
    15421 cctagagggc gaattgctac tgcttatgcc tatgaacatt ttggttacga ctatcatata
    15481 tgatttttgc ttttagattg gaggaaaatg aatgagtgat acaacacgta cgaaacaatt
    15541 gatcaaaaac gtattgattg atttgtgcca aacgcaatct tttcgaaaaa tcagcgtcca
    15601 aaaaatcgca aacgaagcaa aaatcaatcg acaaacattt tattatcatt ttacagataa
    15661 atacgatttg cttcgttggg tctattgtga ggatgcattg cattatttag atccacaatg
    15721 tctttcactt gataattggg aagagcaagc attgaaaatg ctgaaagcaa ttgctgagaa
    15781 gaaagaattt tatgcaaata ctgtgctttc tgacccagaa attttacaaa aagagttttc
    15841 tcaactgatc caaaaatcat ttatcaagat ttttgaacaa atggatgaag aaagacaact
    15901 ttctgcaaga gacaaactat tttatgctcg ttttttttct tacggttgca gtggtgtatt
    15961 agtcaattgg atcacgaatg aatatgaaga aacaccgatg gaaatcgcta tgcagctttt
    16021 ccgtttagcc aaggatacgg aattatattc ttatcgtctt tatgcaaaag aagagttgga
    16081 agaacagtaa tagaaaaatt ttttgttgga aaagcaataa tcgctaaaag gagatgggga
    16141 aatgacaaaa attttatttg tttgtttggg aaatatttgc cgttcaccga tggcagaagg
    16201 cttgctgaga aaacgaatag cattagaagg aagggaagca gaattttttg tggattctgc
    16261 tgctacaagc acgtatgaag ttggaaagac accgcaccct ggaacgaaaa aaatattaaa
    16321 ccaagaaaaa gtagatatga cgaatatggt tgctcggcaa atcacacccc acgattttga
    16381 aacttttgat tggatcattg gcatggatca agaaaatgta gaagaactga aacgaagagc
    16441 accacgctca gcgcagggga aaatccattt gtttttaagt agcattcctg gaaaagaaaa
    16501 agaaaatgtt cccgacccat actataccaa taactttgat gagacatatc acttgatcac
    16561 agaaggcctg aatcattggt ggaatatttg gattgatgaa aataaaataa caaacaattt
    16621 gtaaagttaa cgctttcttt ttaaggcgat gttagagcat ttccttgttt ttttgtaaaa
    16681 tgttaggtaa aataaaatta attaagtaac actttcttag ctaaaggagg agtgcattcg
    16741 atgaacgaag agacagtatc gccaatgaag aagcttacga agttagttac tcatacttcg
    16801 tatcaacttt ttgattcttt tgtaaatgac actgaagaac atgctaagaa tgtacgattg
    16861 caaggaaagt ttattcttga gctgcaaaaa gctgctactg aacatagtct agttatctta
    16921 caagtaagag caaatcgttt gagtagcaag tatgaaacga tctcaggctg ggtggcgaca
    16981 aaaacggtcg aaaaagaccg agtgatgatc cgcctacaaa acgaagagca gcagatccgg
    17041 atggttcctg tagaacaaat tgaaaaaata acaatccttt caccagcagg ggaacaggaa
    17101 cggttatcaa aataatttat accagataga aaagcacgta tgagcttgta ccatcaatca
    17161 ttactaatca aaaataaccg aatgctttaa gctgatatca gtaaaacgga acgttttagg
    17221 atgagtatca cagcatgaca gcattgggtt gattagttga atcgattgga tggtacaagt
    17281 ttttttgata aaaaaaggtc ctgctagccg gggagctagc aggataagga gttaaaaatg
    17341 aaaaagtgtt gttagggttg tttgttggta tgcttatata atagtcacta gttgtgaata
    17401 ttttgtgacg aaagttttcg aaagttgtta agtttttttg cgaaaactat ttttatatca
    17461 tatatatgtc taaaatctat attataaaag aaatgttgtt tgatcagctt ctcttcggta
    17521 ttagttcaaa acaaaacggc aaagtatatg gagctacttt gccgttttgt ttctctaata
    17581 ctcaggtcag tttatagacg ctcaataaac ggtgttcaaa agccagtttc tcggtattaa
    17641 gtcaaattta tgcaaaaatg tgagaagcca ttttcaaaaa atatttctta atactcgaaa
    17701 ctgagcggct ttttcacgac ctctcaataa acagtgttca agagacagcc tatcggcaat
    17761 aaggctgaac gtctctttca caacctcttt tatcaatctg ctacttcttc tttcttagcg
    17821 aaactccaaa tcagtccgat aacaaaaccg ataactgctg gtacgatcca ccccatcccc
    17881 aatttgaaaa acggcaagta gctttccgca acatataaaa gattttgaac aataggtgtt
    17941 tgtttgatag tttctgggca agcgttcaac ccatcaaaaa tcgaagcaat caatgtaaaa
    18001 taagtagtca ttcgataaac agccgtacgc tgcttaaaca aaggaccaac taacactagt
    18061 aaaatcagtg tcattgctaa tggatagatg aacatcaaaa caggcaacga aaattgaatg
    18121 atattcgtca agcctacgtt tgccgctaaa caaggaagga tactagcaag tgcaacaaag
    18181 aatgcgtaat ttctttgcgg aaacaaatct gtgaatgttt ctgcaaaagc tgtaatcaaa
    18241 ccaataccgg tcttcaagca agctaatata acgataaatg ctaataagat actgccataa
    18301 gtacctaaat aatgatcagc aatctgagcc agcgtgatcc cgccattttc acttagagca
    18361 aagctaccta agctcatagc acctaaataa gcgagcaaag tataaatgat tcccatcaat
    18421 ataatgctga tcgcaccaga tttgatcgtg tctttagcga tttcagcagg ttttgttaca
    18481 cccatgtttt ggattgttgt gacaatgatg atcccaaatg ctaaagcagc aagcgcatct
    18541 aatgtgttat atccttgagt aaaccctgtg aaaaaagcat gctcttgata atttggctga
    18601 ataggcgctt gatttacaga acctagtgga ttcaaaaaag caaggagaag caaagcacct
    18661 aataaaacca aaaatgcagg attcaggaac tttccaacat aatctaatat ctttgtcggt
    18721 tttcttgaaa accaccaagc cagcacaaaa aatacaatac tgaaaattgc tagatatagc
    18781 gtctgtctgc taggatcgat aaatggtgct aaaccaatct cgaaagatgt ggttgcaagg
    18841 cgaggtaaag caaaaaacgg tccgataact aagtaaagca agatggtaaa aaccatcgca
    18901 tatgtttgat ttatccgttt tgctaattca tatacacctg agcttttcga tacaccaatg
    18961 gcaatcaccc ctaagaaggg aagaccgata ccggtaacca agaaacctag attcgcccaa
    19021 aaggtagcag cgcctgcttc ttgacccaaa tgaacgggaa agataagatt tccagcacca
    19081 aaaaatagac cgaaaagcat ggagcctata aaaagatagt ctttaaatga taattttttt
    19141 gtcatacata actcctttac ggttttttta aaagtaacaa aatttcgaaa aatatgcaac
    19201 aattttcaga aaatttccta tataaaacga cggttattta ataacgtaag tgataaaata
    19261 aaagcgctga atcatctgag gaggaatcat cgtgacaaag tcgagattag aagcatttac
    19321 tgatggagtg gtagccattg ttttgagagt tcttgtatta gagatcaaga tccctaatac
    19381 atctagcttt cattctttat gggtcatccg aaatacatta ttagcttata ccatcagctt
    19441 tatatttgtt gcggtgatct gggtgaacca tcatcgtata tttcagatgg cagaacgaat
    19501 taattaccga gtggtctggt cgaatatctt tttgctcttt tggctgactt tatgtccttc
    19561 tgttactagt tgggtcgggc gtaaccctga agctttttgg cctgagatgg cttatgtctt
    19621 agtatacacg atgtggagtt tttcttttgg tatcttgatg aggcaaatca tgaaagcaaa
    19681 taaaccagat tcccatgtcg tgagagtttt gtcaaaggac cgtcgaagtc ttatctccat
    19741 gatgattaac ttatgcttga ttgccggtgt cttttttgta ccgttgatcg ggttattcgg
    19801 acgttttttt gtatctggta tttggatttt ttcctataaa aaagcagatg cctattatca
    19861 gcggttgttt ccggggaaat agaaaagagg ctgggacaga agcttttaac tccaagaaat
    19921 aagccgaaat ttcacaaaaa tttaagaagc aattttcgta aattccttct tatttctcga
    19981 agctgaccac ttctgtcaca actactttct tacttcttac gttcatattt catatgatag
    20041 attagtaata gaagcaagaa ccacacaggt gttagtaata aagcgattct cgtatctttt
    20101 cctaggaaca agacgacaca cacaaaggcc atgtaaagaa ataccagata attactaaat
    20161 gggtacaacg gcattttaaa tgaatgagct tttttgccga ggatactttt acgatatttc
    20221 atgtgcgtgt agacaagcat actccagata aacaagaaac aagtagtggc aatactgctt
    20281 actagtgtga atacttcact aggcatcacg taattcaaga taacagaaat gaaaatgacg
    20341 atagtagaaa atgtcaaagc attccctggc acatgatgtg ttgttaactt tttgaatttt
    20401 ttaggggcac tgccttcttg cgctaaagaa cgaagcatac gtcctgtact atatattgca
    20461 ctgttgcagg cagaagctgc tgcacttaat acgactaaat tgatcaagga agcagcaatc
    20521 gtgatcccaa tttccgaaaa tacttctaca aatggactgt tatctggatt caagctgttc
    20581 catggataga ttgccataat gacaaaaaga gatcctaagt aaaataagat gatcctgata
    20641 ggaatattat tgatagcttc cggcaacact ttttcaggat tttctgtttc tccagcgact
    20701 aatccaacta attctatccc agcaaaagca aaggttacca tttggaaagc taagataaat
    20761 ccttttgcac cagttggaaa gaatccgcca tgagaccata gattcgtgat actggctgtg
    20821 ccaatatctg tcgtatagtg ggtgaggatc atataagctc ctacgaggat aaaggcaatg
    20881 atcgctacaa ctttgatcaa tgcaaaccaa aactctaact caccaaacaa tgagacagcc
    20941 accatattca agcaaagaag aagacctaat gcaatcagtt caggaagcca ctgaggaaca
    21001 ccaggcgccc agtagcgtac atacattccg atggctgtta aatcggccat tgcaatcgat
    21061 acccagcaga accaatacgt ccagccagtg atgaaagccg cttttttgcc aagatattct
    21121 gcaacaaaat ccagaaaaga atggttattg gtgtttgata acagaagttc gcctaacgca
    21181 cgcataatga aaaaacagat gcatccagta ataagatagg cgagcaatat cgaagggcca
    21241 gctagctgga tagactttcc ggaacctaaa aacaaccccg ttccaatcgc tccgccaata
    21301 gaaatcagtt ggacatgtct atttttcagt ccacgctgca gttcttgctc ttcattcatt
    21361 tttaaatcat cctaactaaa aaagtttaat tacttccata ttaaaagagt tttctgaaaa
    21421 acacaactaa gattccaaaa ttttcagaaa tttacctttt atgagtaatt cataaaaaag
    21481 aactgcggta aacaccgcag ctctttgtcc caatcagcta ttgatcctaa gcatttaaaa
    21541 tacgtgaaag gaattctttt gtacgttctt ctttcggatg gacaaagata tcttctggtg
    21601 taccttcttc tgcaatcaca cctttatcca taaaaatgac acggtcagat acatcttttg
    21661 caaattccat ctcatgcgtc acgataagca ttgtcaagcc agtatgtgct aagtctttga
    21721 tcgtattaag cacttcgcca accatttcag ggtctaacgc cgaagtaggt tcgtcgaata
    21781 gcaatacatc tggattcatt gataatgccc gagcaattgc gacacgctgt ttctgtccac
    21841 cagataattg tgctggtttg gcttcgatat aacgatccat accaactttt tccagatttt
    21901 cgattgctac ttttttggca gtttctttat ctcgtttcag gacagttgtt tgaccagaca
    21961 tacagttttc caagacattc atattgttga acaggttgaa ggattggaaa accataccta
    22021 gattcgttcg atatttaggt aaattatatt taggagctaa tacattttct ccattataaa
    22081 tgatctcgcc gcctgttggt ttttccagta aattgataca gcgcaagaaa gtagatttac
    22141 cagaaccgga agaaccgatg atcgtcacaa cttcaccttt attgactgtt acgctgatat
    22201 ctttcaatac ttcattttca ccgaagcttt ttcttagatg tttgatttca ataatttttt
    22261 cattcatgat tcttcctcct tattcctgca aatttgaatt gtcgatttct tcaagcttgg
    22321 tataagctga aggaccatcg attttctttt ctaccgcccg caggattctg gtgatcgtaa
    22381 aggtcatgac taagtagatg atcccgacga tcgtaaatgt ttggaagaat tggaaattcg
    22441 caccggaagc agagtttcct tggaagaaca aatcagctac gccgattaca cttaaaactg
    22501 ctgtatcttt gatattgata acaaactcat ttcctgttgc tggcaagata ttccgtaaaa
    22561 cttgtggaat aacaactttt ctcatcgttt ggccatgggt cataccaatg gcttgcgcag
    22621 cttcgaactg cccttcatct actgcaaaaa tccccccacg aacgatctct gtcatgtaag
    22681 ctccagtatt gagagagaca ataaacaaag cggcaatcgt tcggttcaat gaaatgccaa
    22741 aagcgagtgc cagaccgtag aagatgacca ttgcttgtac catcatcggt gttccgcgga
    22801 atacttcgac atagatagaa agaagtgcat ttccgatttt ttggaagaag cgagtcagtg
    22861 catttcctga ttcaggtacc gaacggaaga caccaatcag taatccaagt gtagtaccga
    22921 caactgtccc gatcaatgcg atgaacaagg taagtccagc acctcgtaag aacatattgc
    22981 cgtattgttt ccaaatcgta gtgaaatcag aaatgatgcc aggtttttct tcactatcag
    23041 ttgcagcagg ctgatctttg actgcttggt ccataatttt ggttcgttca tcgttagaga
    23101 tgccagaaag aatctggttt actttttgga tatccgggtc gcctttacgc ataccaacag
    23161 aaatctgaac atcttccggg tttgtctgga agccatctgc accgctgaat tcaagcattt
    23221 ccaagtcttt gttcacacta gttgccgtta caccttccgg acgttcgctg acataaccat
    23281 cgatcattcc agaagctaaa gctgttctca ttgctgagaa attatccatt gcttgttgtt
    23341 tctgcacatc tggtatctga tcgatcacag tatagtggaa tgtatttaac tgagcagtaa
    23401 tctttgctcc agaaagatct gctaaacttt ttgcttttgc atatttgcta tctttttgaa
    23461 ctactactac taattgtgat tcgtaataag gatcggtaaa atcaatttct tttcgtcgtt
    23521 cagcagtagg gctcattccg gcgatgatcg cgtcgatctt gcctgattga agggcaggag
    23581 ccagaccatc ccatttcgtt tggacgatga ctaatttttt ccctaaacca tctgctactt
    23641 ttttagcgat ttgaacatca taaccgccgg cgtaactatt ttggccttga attggcaagg
    23701 cattattctc atctgtttgt tgagaccagt tgaagggtgc atacccagcc tccataccta
    23761 cgcgaaactc atcgctcggt gttttttcat ctgcatttgc cagagatccc acactgaata
    23821 gtgagaagac aaaagcaaat agtacggcaa ctgaaaccat attttttttc atttttttct
    23881 ccctttctga ttatatgata cacgagcggt ctagatgaaa tgcggtaaag ctttatctga
    23941 aaaaataaaa agcgaccgat ttatagatat aaaaaggccg ctaaaattcc ataaggtgat
    24001 aaacctctca caaaacatag cgcaacttag catcactgct aagacagtcc gcaagctctt
    24061 aacttgcgtc ccaacataca ctccaagcaa aaaagtgcac atttcggcga tcctccctat
    24121 tcctgcttct ccatgtttgc ttcactccac agggttaatg attctcgcga cctctacctc
    24181 attgattgag gcatctcgta ttcagttatt tatacaaaaa aagtttacga tactcgagag
    24241 gctttgtcaa tctataactg ctgttttttg aaaaaatact gataaatata gaaatcttta
    24301 cttttaccga aaaaacaatc aaaatgtgaa tcatctatcc attgcaaacg atagtataat
    24361 tatacacaaa aatgtatgta atacaataaa aaaagaacta gaacagaaaa tttcctgtgt
    24421 ccagttccat ctcgatcatt taagctgccg ctttctttgg ctcacgtcct aggatcgctt
    24481 gcaaaagaac aacgacgcca taaatggcta atattagata aatcaaactt gagtattggg
    24541 tgattcccca gccccatgtt cgatatacgg ctaatgtaat ggctaaaaca attgcggcaa
    24601 tcacgttgaa taaagcaaaa gcccaaagat ttccattttc tttgcgtaca agataaaaaa
    24661 cagagaaata aacgcttaac gctaaccagg cgatacaagc cagaataacg ccccaataaa
    24721 taaagaatgg taacatatcg attcacctca cttttataca gcagtattgt aacacgtttt
    24781 cattcttttg tcagtgaaca ttgtgataaa ttgttcaaat gcccataaca cttttttatt
    24841 cccatttttc tgacttttca acaataaatt tgttcgagta tgggctataa tggaaagtga
    24901 ggtgacaaaa catgaaacaa ttaacagtag acgaagcagc aaaagagata ttagcttatc
    24961 agcaaattac atttttgacc ggtgcagggg tatccacacc ttctggagtg ccagactatc
    25021 gatctttgtc aggaatctac cacgggatgg agcagccgga atacttgctg agtcatcaag
    25081 caatggtgaa tgaaccggat aaattctatc aatttgtcaa aaagatttat catcctgaag
    25141 caaaacccaa tatcattcat ttggaaatgg cacatctagc gaaagaaaaa aatgtttggg
    25201 ttgtttccca aaacatcgac ggtttgcacg caaaggctaa aagcccgcaa ctcgtcaatt
    25261 ttcatggaag tttgtatcaa tgtcattgtc gaaaatgtca acaaacggta gactggaaag
    25321 aatatcttca cagcgacaaa catcaagcat gcggaggaca aatacgccca gacatcgtgt
    25381 tatatggtga agggtttcaa gatggagtca tggagcaggc ggcttatgcc gtcagccaag
    25441 cagagctgat cgtcattgtt ggaacgagtt ttcaagttca tccgttttgt gatctggtac
    25501 agtttcgcca gccgtcagcc aaaatcttag taatcaatca aacgcctgtt tatttagcgg
    25561 agccttatac gtttattcaa gaagacggag cggttgtttt caaaaaaata caagaattag
    25621 gagcagatta tgactgaatt caaaaccgaa aaagaaaaaa tgattgcagg cgagctttat
    25681 tttgccaatg atcctgagct ggttgccgac cgtatgtttg caagaagtca aagccaaatc
    25741 atcaaccaag cagaatcagc ggaactgcga tcccaattgt tgaaagagac ttttggccgt
    25801 acagggaaaa aaatctatat ggagccagtt atcaattttg attacggata taatatattt
    25861 gttggggaga atttttatgc aaatttcaat tgtacatttt tagatgtcag cacgattgaa
    25921 atcggtgata actgcatgtt cgctccgaat gtccagcttt acacggcgac gcatccacta
    25981 catccagtga aacgtaacag cggtctggag tacgcaaaac ccattaaaat cggtaataat
    26041 gtttggttag gcggaggagt tatcgtcacg ccgggtgtca ctctagggga caacgtagta
    26101 gtcggcgcag gttcggttgt gaccaaatct tttcccgaca atgtagtgat tgcaggaaat
    26161 cctgctcgta tcatcaagac agtagaggaa gaactaacag aagagtctct tgaaacatta
    26221 cgtcataaga tcgatatgat cgatcgagag ttgattgctt tattagaaaa aagaatggat
    26281 acggtaacta aaataggaca agtgaaaaaa gaagaaaacc aagcagttta tgatgcaaaa
    26341 agagagcagc aagtattgga taaagttgtt agtctgctga aaaataaggg atataaggaa
    26401 acaataacag atacgtatgt tgatttgatg aaacactcgc gcgaatacca aaacaaaatg
    26461 aaggaggaat aagtgtgatc gaaggagaga cacggcgaaa acaaatcatg caaaccttgg
    26521 caaatacaga aaaaccagtg agtgctagca agtttgcgaa aacttttgga gtcagccgtc
    26581 agatcattgt aggcgatatt gctttactac gagctgcagg taaaagtatc gtggcaacag
    26641 caagaggtta tatcctcgaa acagaagaaa ccaatactgg gcacatcagt aaaatcgctg
    26701 tccagcatgg aaaagatcaa acagaagaag aactgagact aatcgttgaa aatggtggtg
    26761 aaatcattga tgtaattgtg gaacatcccc tttacggtga gttagcagga actttgcaca
    26821 tcaaaacgcc acaagatatc gattccttta tgagacgtta tcaaaaaagt aatgctactt
    26881 tgttatccga attaacaggc ggcatccatc tgcatacgat ccgctaccca gaaaagcata
    26941 tgctgaaaaa catcaaacaa aaactagctg aagcaggaat cctctacgaa ggataacatc
    27001 gtagctgcta ctttttatcc tagaaactat tctatcatct ctgagataaa cacccatatg
    27061 gaagaaataa gaaaaaataa gaaaagatgc gtatccaata cacagaattt tttggaattg
    27121 cgatttctag atgtctatct aaatttcgat tagtggagaa acataaaaaa gggaagtgca
    27181 gcttttgagc actccccttt tttataaagc tttcttgtag catagtatcg aaggaacctg
    27241 ccaattctct actcgatcac caatacgcct tcttttagtg caaatggatt ttgatcgttg
    27301 atgtggtcat agaacatcac accgttgata tggtcgattt catgttgaac gacgatcgat
    27361 tcataattct tcaaacgaat cttgtgtttt tcaccattca tatcataata agacacagtg
    27421 attttggcat ggcgaacaac atatcctggt acttctcgat caacagataa acagccttca
    27481 ccttccccta aacaagcatc ttgaacagaa tggctcaaaa ttttaggatt atacataaca
    27541 gtacttagag aaggtccatc tgcctctggg tcaggacttg gtacgtgaac agcaatgatt
    27601 cttttagaaa tatctaattg aggagcagct aagccaacac cgcctcgtaa gtgtagttct
    27661 tcagctttga ttggatcttg gctgtttttt aagaactcaa gcatctcttt tcctaaagag
    27721 atatcttctt cgcttaatgg aagagaaact tcttttgcaa cttcgcgtaa ggtcggattt
    27781 ccttcacgaa tgatatcatc cattgtaatc atggaatatg tacccctttc ttaaaagact
    27841 gtgtttcaag tctattttcg cattatagtt taccacaaaa atggaaaagt agtagtaaga
    27901 ttgtttgaaa actacctttt cttaatgatt aactacttga ttttcaaccc ggtttcaggt
    27961 aaagtatagc tgtgtgctct aggcacatga cctgccactt ggttaagcga atcaccaacg
    28021 ttttactcag tcgcagggga ataatcgaaa gaggtgaaag aaatggcaat ttcaaaagaa
    28081 cgcaagaatg aaatcatcaa cgaatacgct cgccatgaag gggatactgg ttctccagaa
    28141 gtacaaatcg ctgtattaac tgaagaaatc aaccacttga atgaacatgc acgcgtgcac
    28201 aaaaaagacc atcattcata ccgcggccta atgaaaaaag ttggtcaccg ccgtaacttg
    28261 ttagcttact tacgtaaaac tgacgttcaa cgttaccgcg aattgatcaa acgtttaggc
    28321 ttgcgtcgtt aattttagtc aaaaagagtg ggattcacat gaatctcact ttttttactc
    28381 gtatatcaat taagtaaaat tccgtgatca agctagatgg actcctacta accaaatgaa
    28441 agctgctcaa aagacggctt tcggcagttt tcatttgttt agtagcgtct tgctttcacg
    28501 agaaggaaaa ggagaagtta tgtcagaaaa acaagtattc aaaacgacat ggggcggccg
    28561 tcccttacaa atcgaagtcg gtcagctagc aaaacaagca aacggagccg ttttagtccg
    28621 ttatggagat acagtagtct taagtgcagc tgtggcctct aaagaagcaa aagatacaga
    28681 ctttttccca ttaacgatca attatgaaga aaaaatgtat gcagcaggga aaatccctgg
    28741 aggtttcatc aaacgagaag gccgtccaag tacggaagca acattgactg cccgtttgat
    28801 cgaccgtcca attcgcccga tgtttgcaga aggcttccgt aatgaagtcc aagtaacgaa
    28861 catcgtgatg agtgtagaaa cagactgctc gccagctatg gcagcaatgc taggttcttc
    28921 tttagcacta tcaatctcag atatcccatt tgacggccca atcgcaggcg tagaagttgg
    28981 tcgtgtaaat ggcgagtacg tcttgaatcc aacagtagaa caagcagaac aaacagatat
    29041 cgaattgact gttgccggaa cgaaacaagc catcaatatg gttgaaagcg gcgcgaaaga
    29101 agtttcagaa gaagacatgc ttggtgcatt gctgtttggt tttgacgcta tcaaagagtt
    29161 agttgctttc caagaagaaa tcgttcaagc agtagggaaa gaaaaaatgg aagtgacttt
    29221 actgcaagtt gatgaagtat tgaaaaaaga aatctttgat gcttcttacg ctacaatgaa
    29281 agcagcagta atgactgaag aaaaacttgc tcgcgaagat aatatcgagc aggtgaagat
    29341 cgatatccgc gaagcttatg ctgagaaatt tgcaggtcat gaagatgaag atcacttgtt
    29401 gaaagaagtt aaacaaatca cagaagatct tgaaaaagat gtcgtacgtg aattgatcac
    29461 catcgataag atccgtcctg acgggcgtaa attggatgaa atccgtccat tgtcatcaga
    29521 ggtcagctta ttgccacgtg tacatggatc aggtttgttc acacgaggac aaacacaagc
    29581 tttatcagct tgtacactcg cacctctagg agagcaccaa atcattgatg gtttaggggt
    29641 ggaagtcagc aaacgattca tccaccacta caatttccct caattttctg ttggttctac
    29701 aggacgtgca ggctctccag ggcgtcggga aatcggacat ggcgcattag gtgaacgtgc
    29761 gttagcacaa gtaatccctt cagaagaaga atttccttat acgatccgtt tagtagcaga
    29821 agtattggaa tcaaatggtt cttcttccca agcaagtatc tgtgctggca cattagcatt
    29881 gatggatgca ggtgtaccaa tcaaagcgcc agtcgccggt attgcgatgg gacttgtttc
    29941 tgatggtgaa aactatacga tcctaactga tatccaaggg ctggaagatc atcttggcga
    30001 tatggacttt aaagttgccg gtacaaaaga tggtatcact gctttacaga tggatatcaa
    30061 gattcaagga atcacagaac aaatcctaac tgaagcatta actcaagcaa aacaagcacg
    30121 tatggaaatc ttagaagaat tgacttcaac gattgctgct ccacgtgaag aattaagcca
    30181 atatgcacca aaaatcgaaa tgatccagat cgaacctgct aaaatcaaag atgttatcgg
    30241 taaaggcggc gatacgatca acggaatcat cgatgaaact ggtgtgaaaa tcgatatcga
    30301 tcaagatgga aaagtaagta ttgcttcagc tgatgcagaa atgatcaaaa aagctatcaa
    30361 gatcatcgaa gatttgacca aagaagtcaa agttggtgaa gtttatctag ggaaagttgt
    30421 ccgtatcgaa aaattcggtg cattcgtcaa cttgatcaaa ggaaaagatg gacttgtcca
    30481 tatttcccaa ttagcaaacg atcgtgtcaa taaagtcgaa gatgttgtta aactaggtga
    30541 tgagatcctt gtgaaagtaa ctgaaatcga taaacaagga cgcgtaaatc tgtcaagaaa
    30601 agcaatgttg aacgaagatg gttcaacgaa aaatgaagaa aaataattta attcatagga
    30661 ataatgtact tgtgatcgtg aaggtgacag ggggacaata attattcgaa aaaaggggac
    30721 tgtgacaaaa gccgtgtcac agtccttttt tttcgaataa acggtgttca aaagcttgca
    30781 tctgcggtaa taagtccagc caagttaaaa acattaggag ctgtttttat ttggctgttc
    30841 ttattacttg atgcagaaca gcttttttac aacctctcca ataaacgatg ttcaatcagc
    30901 tgtccctcga tattagctca aaaaacggca aaatatgagg aactattttt ccgtttgttt
    30961 ctctaatact caggtcaaac cgctgatttc acaacctctg attcacggtg ttccagaagc
    31021 agcttctacg gaaataagct gaacactttt gttacaactt ctttttttct ggagtttctt
    31081 ggcgcatatt tttggagtcc ttctgaataa agcgtaaaat aaaagtgaga aatatggata
    31141 aaggagggaa aggagatgct gaatttttta tggtcgttat ttatcggcgg tatattaggt
    31201 ttgatagctg gcgcaatttt aggaaaggaa gtcccgggag gcgtatctgg aaatatcatt
    31261 atcggttttt taggtagttg gctcggcgaa tttttactag gaccactggg accggaactc
    31321 ggcggttttt atttgatacc agcattattg ggtgcaattt tttgccttgc tctttattca
    31381 tttgtggcaa gacgtatcag agaacgtcca aagaaagaat aattttattc aaataagttg
    31441 acacttcagt gtgttacttg gataattaga agcaatttag gaaagcgggt gtcatggata
    31501 agaatatcat ctatcattca agcttaccta aaggatatcc atataacaag aaatgaggga
    31561 aaaacgtggc aacaacgcac aataccaaaa agatatcaat gactggcctg cttgtagcga
    31621 tgggagtcgt ctacggagac atcgggacaa gtccgcttta cgttatgaaa tcgattgttg
    31681 aagataatgg cggattgtca ggaatcaatc ctgattttgt tatcggatca gtctcattga
    31741 ttttttggac attgactcta ctgacaacaa tcaaatatgt cgtgattgca ttgaatgcag
    31801 ataaccatgg tgaaggtgga attttctcac tctacacact tgtccgaaaa ggtgggaaat
    31861 atttgatcat tcctgcaatg atcggaggag ctgccttact agcagatggg gtattgaccc
    31921 ctgctgtgac ggtaacgact gcgattgaag gcttgcgagg aattccgcag ttttttgacc
    31981 ggttcggtaa taaccagaac gtgatcgtca ttatcacttt agttattatt tttgttttat
    32041 tcatggtcca acgctttggt acagatattg tcggaaaagc attcggacca atcatgttcg
    32101 cttggtttac ttttttaggc gtaatgggat taatgaactt cagtcaagac tggacagtta
    32161 tccgtgcact gaatccttat tatgctatcc agctgctttt tagtgcagat aacaaattag
    32221 gcttgttcat tcttggaaat attttcctgg ctacgacagg tgcagaggcg ctttattccg
    32281 atcttggaca tgtcggcaaa cgaaatattc gtctgagctg gccttacgtc aaaatttgtt
    32341 tggttatcaa ttattttggg caggctgcgt ggttgttgaa tgtttatcaa aaccctgaag
    32401 cacagcaaat caagaacctg aatccattct tccaaatgat gcctcaaagt tggatcgtga
    32461 tcggcgttgc ttttgcaaca gtcgctgcag tcattgcttc gcaagcattg attacaggtt
    32521 cgtttacgct agtttcagaa gcaatcaagt tgaaactgct gcctcggtta aagatcatgt
    32581 atcctgggaa cagtatcggg caaatgtata tcccagcagt caatctgatt ttatggatcg
    32641 cctgttctct agtggttgtc acattccgaa cgtctcatca tatggaagct gcttacggtc
    32701 tatcgatcac tgtgacgatg ttgatgacaa cagcactgct ttacttttat cttatccaaa
    32761 atgggcattc tcgttggctt gcatatttag ttaccttttt cttcggtgcg atagaagtcg
    32821 ttttctttat ctcaagtgtt gtcaaattct tccgaggcgg ttttgtagcc gttctgattg
    32881 gtttgatcat cttagtcgtg atgtttattt gggaacaagg gaacattatt cgcgaatcgt
    32941 caaccgagga tgtgtctttg agagattata tcccgcagct tagagaatta cgtgatgata
    33001 cttctttacc aatctatcag acaaatgtgg tcttcttggt tcctgatatg gctgaagata
    33061 aagttggccg acagttcatc tattcgattt tagataaacg gcctaaaaga gcacgagtct
    33121 attggtttgt tcatgtggaa gtgacggatg agccatatac gaaagaatat caagtagata
    33181 tgatggacac tgattttatt gtccaagtga atctgttctt aggtttcagg gtccaacagg
    33241 aaatcaacgt atatgttcgc caagtcatcc atgatttgat gaaacaaggc cgtttgccaa
    33301 aacagccaca aagatactct ctgacaccag ggcgagaagt tggcgatttc caatttgtcc
    33361 tgattgatga agtagtttcc aatgtgacaa ctctaggaaa atggcaacgt caaatcatgc
    33421 aggcaaaact ggcaatcaaa aaaatcgcta cctcgccaga aacatggttt gggctagagt
    33481 acagcgaagt aaaacatgaa actgttccgc ttatcattgg aaatactcgg aaaacatggt
    33541 tgaaagagcg gttgtgaaag tagcgctttg acctgaacta atgtcgaatg tcagctactt
    33601 gaacaccgtt tatcagaggt catgaaaaag ctgtactgca acaagcagta agaacgagca
    33661 gataaaaaca gcttctcatg tttttcatct gtttgggctt aatgccgtag atgcaagctt
    33721 ttgaataccg tttttatcag aggtcatgaa aaagctgttt agcaacaagt aacgcaatga
    33781 ttttgaagtg ataaggagat gtggctgaaa aatgccgcat ctcctttttt attcctaaat
    33841 atgaatacgc attattttca atctttttgt agaaaaaggg tacaatagaa aaagagaaag
    33901 gcgggagaat atggttatca atttcattat tttatttttg atgattgcaa ttacttcatt
    33961 ttttgtagca agtgaatttg ctttagtgaa aatcagacga tcaagattgg aacaactaga
    34021 aaaggaaaat gtaaagaacg ccaagctagc tcttcatgtt acacaccatt tagataacta
    34081 tttatcagct agtcaattag gaattacgct aaccggtttg atcatcgggt gggtcggtga
    34141 aggatctgtc gcggctttac tagaaccagt gatcggtaaa ctacctttta gttcggctat
    34201 tagcagtaca atctctgtgg cgctgggatt tattttagtt acgtatatcg atgtggttat
    34261 tggcgaactg cttcctaaga gctatagtat cgtcaatacg gagaaggtcg tcttgttcgt
    34321 agttaaacca cttcattatt tttataaagt aatgtttcct tttatttggg tattgaatca
    34381 ttcagctgca gggctaggga agctattagg tgtgcgtctc gtatctgaag gagaagagac
    34441 attgtctcaa gaagagctga cattagtcgc attgaattct tatgaaaaag gagagttgac
    34501 caaagaagaa tattattatt tggaaaacgt gtttgaattt gatgatacct tggcaaaaga
    34561 tatacaagta gaccgtacgt ccatgcaagt attcgaagct tcagaaaccg tcaaagaagc
    34621 gataaaagct tcgattgaac aaggacatac tcgctatccg gttatcttag aatcaaaaga
    34681 caatgtttta ggttatgtca ccttgccaga tttgatcaag caatcttata aagatgacca
    34741 gctgacagta gaacagttga ttgaagagcc gatcgtaaca actgaaacga tccctataaa
    34801 aaaattattg acgatcatgc gaaaaaaggg taagcatatt gctatcttaa aagatgaata
    34861 cggagggaca agcggcttag tgacgattga agatatttta gaagaaatcg tcggggaaat
    34921 ccgagatgag acagatttgg acgaagcatt gatagcggaa cagtcagatg gctcttatat
    34981 catctccggc aaactaacat tagatgattt ccagcgttat tttcatgtag agattccaga
    35041 gtttgaagaa acgaatttta ctacacttgc gggctttgct tctagccgat ataaagaaat
    35101 aaaagcagga acaatcattg agattgcatc attccgtttc acggtattag aataccagca
    35161 tgcacatatc gattatttca aagtagagtc cacggaaaga aaaacagaat aaaagaaaaa
    35221 aggctgtgac attttttgtc acagcctttt tgttatctaa aaaacctgtt ttcggtaaac
    35281 gaagaagata ttttcaataa aagttttcat ttttagccgc aacgatttct tttaatcaag
    35341 gctatcttgc ttctgcatgt tctaatgtga aatgttcctc ttcacccatg tgtttcaatt
    35401 gtttcatcga acgcatataa gagtaaagca acacggcaac agaaccgatc caagctaaag
    35461 gagaagctgc tgctgctcct gggtatcccc acattcctgt aagaacgata gctgcaaaag
    35521 aacgcataag caattccatc ataccggcga tcgtagggat cttgctttgt ccaagccctt
    35581 gaagtgtgta gcgtaaaatg aacaggactg ctaagatcca gtaaagagac ccattgatat
    35641 tgaagtaggt ttgtgctaat tcaaatacac gtgtttctga tgggctaaca aacaattgaa
    35701 caaagaaatg accgaagaaa atgacgatag cacctgctaa gagactaaat ccgacactca
    35761 tcagtaaagt ttgacgtacc ccttgcaaga ttcggccata ttctttcgca ccatagtttt
    35821 gtgcagtgaa agttgccatt gcaataccaa atgacatcat cggctgattt gcaaattggt
    35881 cgatacgacc agcagcggct tgagcagcta cgacatctgt ccctagacta tttagtgctg
    35941 cttgtaacac gatagcacca acagcgatga tcgaagattg aaacgccatt ggcaaagcag
    36001 catttaggtg tacagcaaac tcttcttttt caaatttgaa atcttttttg cgtaactgta
    36061 acaaaggcat ttttttcttg atatacacta gacacagtac gctggaagaa acttgtgcga
    36121 ttactgtagc aatagctgca ccttccacac ccatgccaaa atagataata aagatcaaat
    36181 caagtacgac gttgatgatg accgcaatga tcagaaagaa tagtggtgtg cggctgtcac
    36241 caagtgcgcg aatgacatta gaaagcaaat tgaaactgac tgatgcaaag atccctaata
    36301 aaataattga aataaatgtt tgtgcttgat caagtatttc aggaggagtt tgcatcaatt
    36361 gaagcatcgg acgaataaac aggagactta ggacagttaa aatcacagtg acgacaagac
    36421 taatgacaac actagcagca aaacttttct tcagaccccg ataatctttt gcaccgtaac
    36481 gttgtgcggt aataatggct aaaccagctg ttaaaccttg ggcaaagcca atgatcaaaa
    36541 atgtcaggct tccagttgca ccaaccgctg ccagcgcatt tttacctagc gtctgaccca
    36601 cgatgatcat atcgatcata ttgtagaact gctgaaaaac atttccgatc agtaaaggaa
    36661 cagtgaacat caaaatcagt ttagcggggc ttccttttgt taaatcgcgc atcttttaaa
    36721 ctccttatat ctttaaaatt tagttagtag tatatagcgt ttatcctgag aataccaatt
    36781 agaaatcaat gataatttat gaaactccat aaaaagaagc caagaattga gtcaaagaat
    36841 caacaacttg gcctggtctg taaaataagg gacatccacg tttatctatc accttaatat
    36901 tgtctaatct cacttggtaa aaggatcgtt tctctcgtac cgtcatcata ggcgtatact
    36961 tgagcaggaa attggttcga ataggcaaac ggcaaatcaa tatccatttc cacattgctt
    37021 cctgcttgag aaaaatgcat cgtcactttt ccacgatttt cgatcaaatc aaaggttaat
    37081 atattttcta atggaatgac tcccttaaga tctaggtcaa taataaacca tatactgtca
    37141 atcaattcat ctggcaaact tgatacgaca ccaactgaag cgtaacggtt gcggctgcta
    37201 tcaaaacttt caaacatctg tttaacctcc ttcgaatcaa cgaatgtttt atttttataa
    37261 ttaatcctag gataaactag aaatacttac ttcaacgagg gttcattcta ataaagaatc
    37321 aggaaaaatg caacaataat tgaatacttt ttttcaaagt ataaattttt ataaaggtac
    37381 gataaaagta tgcgaggaaa agcttggtaa attaggattt ttcgtttgta aagccattta
    37441 caaaagtgga agccccatat gaaaataaac gattagaaat aaaaaaggcg tgttaaaagc
    37501 tgctgacccg ccgcttctaa caccacctga ttgtttcagt attattcttc tgttgaaccg
    37561 atcacttctg gttcgccacc ttcacctgtg ctttcttctt cttcactttg agcgactaca
    37621 gcagcgattt gctcttcact gtcggtcacg aatttgtaat cgtcgttttt tggaagatcg
    37681 gctactgtaa tagaatcacc taattccaag tttgtcacgt caacttcaat tcgttcaggc
    37741 aatttgtctg gtgtagcaga tacgactact gtatacaagt tttgagctaa cactccacca
    37801 gatttagcac ccactgattc gccaacaaga acgacttctg tttcgacttc tgtttcttcc
    37861 gacatgttta cagatagaaa ttctgcatgt tcgaaatgat tggtaaaagt gttcgtttgg
    37921 atcttgtgaa ccaatgtatt gactttttgt ccatcgatgt ccatcgtgat gactgtgttc
    37981 gctccatgtt cacgcaacaa tttgcttagt gtcaaaccat cgaatgagat aggggtactt
    38041 tctactttat acccataaac aacagctgga actttccctt cgtgacgaag tttgtttctt
    38101 aatgaacggg gacgtacttc tcttttactt acttctaatg atactgacat aaccaaaatt
    38161 cctccttaaa atgtgactgt ctgctttggt aacggacaga ttttatttaa gtgaattcta
    38221 aaggctaatc tcgtgcacat catcgaaggc agggcgctta aaaaagcgca aaaggagaga
    38281 tgcgcgcatc tccccttaga aagtcaggat tcaacttttc tccaccaggt cattacgctg
    38341 tgtatgagaa atccaattca ctttactatt taaccgtaac gtgaactgtt aattaagtca
    38401 aggaataact atgatgatgt atttgcaagc aagaatattc aaggtataat taattagtag
    38461 taataagaaa ggaaacagca tgcgtttaga taaattaata gaagaaaaat tagaaacgac
    38521 acgcaaggaa atgaagcggc tgtttgcttt gaagcaagtg atgatagatg gcacagtcga
    38581 atttcgacaa aatcgaaatg tagatagttt actgcatcaa atcgaagtag caggtgaaca
    38641 cttagaaaca aatgagtcct attatcttct caataaacct gaaaaagctg ttacagctgt
    38701 atcagatcca gaaaagacga cagtaatcga tctgattgca agtgccgatc gtttccaacc
    38761 attatatcca gtgggaagac tagatagaga tacaacagga ctattgctga tcacttcgaa
    38821 tggacaattg ggatatgaaa tgctacttcc agaaaaaaag gtttcaaaga cttatcaagt
    38881 agttgtgaac gaaagggtga caccggcaga cgtaacagca tttgaaaatg gaatcgtatt
    38941 cgctgatggg tatcaatgta agccggctga tttaaaaata ctcaaagcag acaagcacca
    39001 aagtacggtt ttattgacga tccaagaagg aaaattccat caagtcaaaa agatgttctt
    39061 agcccaagga aagaaagtga ccgcattgaa acggctaagc atgggaccat tggaattaga
    39121 tgaacagcta ggagtaggcg agtatcgatc gttgacatta gcagagatga aaaagttaag
    39181 tatttatttt aaataggagg tcaaaaagat gaaatataaa actttattgt ttgatgtaga
    39241 tgatacattg ttagattttc aattaactga agccaatgct ttaagtgctt tgtttgcaga
    39301 acaaggaatc acattgacac cagaaatcga aaccagctat aaggctttga atcatcattt
    39361 atggcaggag tttgaaaaag gcagactatc acgagaagaa ataataggca gtcgttttgg
    39421 gttacttttc cagcaatttg ggaaaacagt agatagtgat caaatggaaa aacgctaccg
    39481 ccactacttg aaccaaggtc atgatcttgt tccaggaagt ctagaaatcc tgaaaaaggt
    39541 ccatccgcat gctgatcttt atattgtgac gaacggtgtg tcgcacacgc aacatcggcg
    39601 attaacagat gcaggaatgc ttgattactt caaggatatc tttgtctcag aagctgtcgg
    39661 agcgcaaaag ccgatgaaag aattttttga tcatgtcttt tcccacattc ctaattttga
    39721 taaaaagcaa actgtgatca ttggtgattc tttgacttct gatatcaaag gaggaaatat
    39781 ggcagggatc gatacgattt ggttcaatag aaataaatta ccagaaatcg aagaaatcca
    39841 gcctacttat cgaatcgatt cattagagga actttattca ttattggaaa ttgaaaagga
    39901 ttaattttca gaaaaatata gcattttcgt gttttttcgc tataatagat tagaatgaaa
    39961 aaacggatac gaaagaggtt ttagtcaatg acaaaaagca agccaattat cattggtgtg
    40021 acgggtggat ccggaagcgg aaagacaagt gtcagccgtg cgattttcaa caacttcccg
    40081 gaccattcca tcatgatgct tgaacaagat tcttattaca aggatcagag ccatttgagt
    40141 tttgaagaac gattgaacac aaattacgat cacccatttg cctttgataa tgatctgctg
    40201 attcagcatg taggcgactt actgaactat aaagccattg aaaaacccgt gtatgactat
    40261 gtagcgcata caagaagtca ggcaacgatc attcaggaac caaaagaagt gatcattcta
    40321 gaaggaatcc tgattttaga agacgaacgt ctgcgtgact tgatggatat caaagtatac
    40381 gtagatacag atgatgacat tcgtatcatt cgtcgtatca aacgggatat ggaagaacgg
    40441 ggacgcacat tggactccgt gatcgaacaa tatttgacag ttgttaaacc gatgtatcat
    40501 caatttatcg aaccaacgaa gcgctatgcg gatatcattg ttccagaagg cggagaaaac
    40561 cacgttgcta ttgatttgat tacaacaaaa gtagctagtt tcttaaacca taaatagtgc
    40621 gcagcgaaac agttgaacgg actgcgaccg tttgaaaagc aaggattctg ctttttgaac
    40681 agtcaccagc caactgtttt tttatttata acaagaggtt gtgaaaacag catcttgacc
    40741 taagtattaa aaagaagaaa cggaaaatag ctgtttatat tttaccgttt tttgagctaa
    40801 taccgaaggt cagctgattg agcaccgtga agtagaggtt gtaaaaaagc tgtctttgca
    40861 tcaagcgata agagcatcca aataaaacag ctcctcacgt ttttcgttgg gttgggctta
    40921 ttatcgtaga tgcaagcttt tgaacaccgt ttaacgagag gttgtaacag aagtggtcag
    40981 atgcaataaa taagaagaaa cttacgaaaa ttatttctcg aatttgtgtg agatttcgac
    41041 ttattttttt gaagaagctc ttttgtcgca ccccc
//
LOCUS       DAPBAF010000025        40472 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.025, whole genome shotgun sequence.
ACCESSION   DAPBAF010000025 DAPBAF010000000
VERSION     DAPBAF010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 40472)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40472)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40472
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.025"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            208..1014
                     /gene="proB"
                     /locus_tag="RD451_001506"
     CDS             208..1014
                     /gene="proB"
                     /locus_tag="RD451_001506"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HDT7566774.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            1011..2258
                     /locus_tag="RD451_001507"
     CDS             1011..2258
                     /locus_tag="RD451_001507"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HDT7566775.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVIGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            2334..2678
                     /locus_tag="RD451_001508"
     CDS             2334..2678
                     /locus_tag="RD451_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566776.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(2795..3121)
                     /locus_tag="RD451_001509"
     CDS             complement(2795..3121)
                     /locus_tag="RD451_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566777.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(3736..4938)
                     /locus_tag="RD451_001510"
     CDS             complement(3736..4938)
                     /locus_tag="RD451_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDT7566778.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
     gene            5055..5570
                     /locus_tag="RD451_001511"
     CDS             5055..5570
                     /locus_tag="RD451_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HDT7566779.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(5769..6215)
                     /locus_tag="RD451_001512"
     CDS             complement(5769..6215)
                     /locus_tag="RD451_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HDT7566780.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(6262..7740)
                     /gene="msr(C)"
                     /locus_tag="RD451_001513"
     CDS             complement(6262..7740)
                     /gene="msr(C)"
                     /locus_tag="RD451_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HDT7566781.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(8094..8723)
                     /locus_tag="RD451_001514"
     CDS             complement(8094..8723)
                     /locus_tag="RD451_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDT7566782.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMKPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITMFE"
     gene            complement(8707..9171)
                     /locus_tag="RD451_001515"
     CDS             complement(8707..9171)
                     /locus_tag="RD451_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDT7566783.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(9658..10926)
                     /locus_tag="RD451_001516"
     CDS             complement(9658..10926)
                     /locus_tag="RD451_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HDT7566784.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(11157..11894)
                     /locus_tag="RD451_001517"
     CDS             complement(11157..11894)
                     /locus_tag="RD451_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDT7566785.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(11961..12530)
                     /locus_tag="RD451_001518"
     CDS             complement(11961..12530)
                     /locus_tag="RD451_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HDT7566786.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            12658..13530
                     /locus_tag="RD451_001519"
     CDS             12658..13530
                     /locus_tag="RD451_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDT7566787.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKVFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            13872..14744
                     /locus_tag="RD451_001520"
     CDS             13872..14744
                     /locus_tag="RD451_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDT7566788.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            14741..16699
                     /locus_tag="RD451_001521"
     CDS             14741..16699
                     /locus_tag="RD451_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDT7566789.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAATRPAQTNTVVKTETFAGGTIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVKEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(17031..17882)
                     /locus_tag="RD451_001522"
     CDS             complement(17031..17882)
                     /locus_tag="RD451_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDT7566790.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKKLEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            18005..18472
                     /locus_tag="RD451_001523"
     CDS             18005..18472
                     /locus_tag="RD451_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HDT7566791.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(18735..19217)
                     /locus_tag="RD451_001524"
     CDS             complement(18735..19217)
                     /locus_tag="RD451_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HDT7566792.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVIA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(19317..20180)
                     /locus_tag="RD451_001525"
     CDS             complement(19317..20180)
                     /locus_tag="RD451_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDT7566793.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGARLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYELVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            20778..21653
                     /locus_tag="RD451_001526"
     CDS             20778..21653
                     /locus_tag="RD451_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566794.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPQFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKTKETVKKDDFNEK"
     gene            complement(21798..21950)
                     /locus_tag="RD451_001527"
                     /pseudo
     CDS             complement(21798..21950)
                     /locus_tag="RD451_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
     gene            complement(22218..23549)
                     /locus_tag="RD451_001528"
     CDS             complement(22218..23549)
                     /locus_tag="RD451_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDT7566795.1"
                     /translation="MGKSSRKDIVFEKFGIVATKLGNQIHLRTLRDAFATFMPFMMLA
                     GFVTLINSVILEPTGFMGEIVDTSTLTTLQQIGTSIANGTLSITTLLVVAAVSYHMCA
                     SRNYTNHIAAVLVAISTFVVLTPMQMMFTPENADKAVEVTGVIPISYTGASGMFVGIF
                     VGLAATELFIKLSNNKKLQIQLSGNIPPAVLKSFNVLIPIIITITSFALLSFIIIQLF
                     NMDINKLITTIVTEPLSKITTGLPGFLLITSIANLFFGFGIHQAVISGSLLDPFLIQN
                     MQENMAAYANKEQIPHIINMAFKDTFAVMGGSGNTIALLIAIFIFSRRKDYKDFAKLS
                     VTPAIFNISEPIIFGLPIVFNISLIIPFVLAPIFSLTVAYFATAVGLINHVVVQIPWT
                     TPPVISGFLATAGDWRAAVLQILIIAASVFIYLPFLRIDEHVTTKLSENET"
     gene            complement(23698..24411)
                     /locus_tag="RD451_001529"
     CDS             complement(23698..24411)
                     /locus_tag="RD451_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016611336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDT7566796.1"
                     /translation="MKKIAKYMEIYLDIKKKIVNGEYKIGEKLPTGDELAVIYHTSKL
                     TVKKGVDLLVSEGVLRSRSGYGTEVVRTPIDNSRVLGPNEGLFSVVGEEHVDSEIHTF
                     SIELPSKKVADKLSISVKDYVYNIVRSRFIDCQPYSIEQTFMPLAVIPGLEPKHLKKS
                     VYAYITNELGLEIKTSHIRIKGDTANEFDAKILKIDPGEFMIEIDKVVALSSGKPFEY
                     SVSRHLYQDFVFEAVFVEK"
     gene            24586..26010
                     /locus_tag="RD451_001530"
     CDS             24586..26010
                     /locus_tag="RD451_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDT7566797.1"
                     /translation="MTTMKKLTFPDDFWWGSAWSAEQAEGKGETGKAETIWDRWFKEQ
                     PYRFYQRIDSSITTDHIHQYKEDIELMKKTGHNSFRVSISWARMFPNGGTGKVNPKAI
                     SFYRKLFSEMNNNGIKVFANLYHFDMPATLQDKGGWESREVVDAYVHYAETCFKEFGD
                     LVCHWFTFNEPLGPILGTYLEDFHYPNLIDFKRGAQAAFFTILAHAKAIQVFKELALP
                     SKIGVILNLSPTFPRSQNPADVKAAEIADLFYTRSFLDPMVKGNFSKKLILLLQEYNQ
                     LPEDYTKEDLVCIYENTAQILGLNYYEPRRVKSRSSMVDTSSPFLPEWFFEPHIMPGR
                     RMNEYRGWEIYEKGIYDLCMDIKNHYGNIEAFISENGMGVADEERFMDDTGQIIDDYR
                     IEYIKDHLAYLWKAINEGCNIKGYHLWTFIDCWSWINAYKNRYGLVSLDLTTQKRTIK
                     KSGEFYKQLSDTNGFRYDVDLLVE"
     gene            26309..27016
                     /locus_tag="RD451_001531"
     CDS             26309..27016
                     /locus_tag="RD451_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HDT7566798.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLIYAGSAQFITVSMLASHSPLLSIVLSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVILV
                     VTLIGCGLGVWIKHAFF"
     gene            27003..27326
                     /locus_tag="RD451_001532"
     CDS             27003..27326
                     /locus_tag="RD451_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HDT7566799.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRILPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLVGILSLS
                     LIRLL"
     gene            complement(27415..28452)
                     /locus_tag="RD451_001533"
     CDS             complement(27415..28452)
                     /locus_tag="RD451_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HDT7566800.1"
                     /translation="MSEKELMKVVGFYEGLSIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGAGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHIL
                     GKVVVSGPFNG"
     gene            complement(28773..29756)
                     /locus_tag="RD451_001534"
     CDS             complement(28773..29756)
                     /locus_tag="RD451_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="HDT7566801.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKEPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILDTFEKEHPTLFSEQ"
     gene            complement(30171..30941)
                     /locus_tag="RD451_001535"
     CDS             complement(30171..30941)
                     /locus_tag="RD451_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7566802.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMISGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            complement(30934..31869)
                     /locus_tag="RD451_001536"
     CDS             complement(30934..31869)
                     /locus_tag="RD451_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7566803.1"
                     /translation="MANALEINNLKKVYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDTDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYETKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            complement(32185..33834)
                     /locus_tag="RD451_001537"
     CDS             complement(32185..33834)
                     /locus_tag="RD451_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HDT7566804.1"
                     /translation="MGQREFIVLIIIAAVILLVALDIFSRLKLKETVRSKWEKIPYQP
                     RFDKEESLKEAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDQQLEKLIAFYQENPQLREKIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGLGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKLPTPLQEELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAILNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLDYPETLVETAKTEAALFDEKRQWHVLG"
     gene            complement(33951..36554)
                     /locus_tag="RD451_001538"
     CDS             complement(33951..36554)
                     /locus_tag="RD451_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HDT7566805.1"
                     /translation="MVNAHIIQHTHWDREWYFTNEDAIVLSDQVFTEVLDELERNPKV
                     NFCLDGQTSIVDEYLEINPQKLKVIQRLMKTGQLFVGPWYAQTDALLVDAESILRNLM
                     IGISDTILKYGDPMMVGYLPDTFGFNANLPTLLHQVEIDNFMCWRGLNFETMVPSPYF
                     IWKGLGDKFVYAMNFPFGYMTGMMTLDAIKDIPEFAKEKLDEAVEMLHMQGKNKDILV
                     PSGVDQKSMILNFDQVVEKLNKYSKFHNIISDYPSYVEVIRNKKELPEYKGELRQPVY
                     SRVHRSIGSVRTKMKIENFKLEQKILKRVEPLMLIAERNGIHISKGLLRRLWKKILQN
                     QAHDSIGGCVSDNVAEDIFHRIKEANEIADGIENLIVKRMADALKLKSNEVLVFNTTT
                     ENYSGSKIVHVVADSKKIHFKGSPYNIIEKEVYFPERKNAYRMIATGFEYFDEPAYYE
                     LDIKINVNVPALGYTVVEFEKNNEKLETAIEIDKTEISNNKYKLSFKDGQLNLIVGDR
                     QYLDFVHLIDSANDGDTYDYSPLEGDTELSLKLETAKVYKDSLQETLVVYGKAQLPKD
                     LKDRLSEKPEMEEISYEISFSLGESQIVEGTLKIHNTVYSHRMRLAINVLDKSEKSIA
                     QIQNGFIENTPDVIPPNWSETMVEKPVNLEIFDKSVSVAENDHYFTFYADGLKEYERI
                     ENQLIITLFSTTGELGKPNLAWRPGRASGDTTNEGHVMMETPLAQEIGEYKVTFGFNV
                     EEGRFNEFKVAKQAEKRLEQSISYQKQKLNVFIHRLDNKIWPLQNELDVPRKFSLIEL
                     PEDLIVSSIYPSYFHEQGFVLRLANPTEQEKIVPEAILSLGTVVNALENKQELTTIPP
                     YDYLSILINER"
     gene            complement(36566..37615)
                     /locus_tag="RD451_001539"
     CDS             complement(36566..37615)
                     /locus_tag="RD451_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HDT7566806.1"
                     /translation="MEFKKQGREILNHFQSGVSYMIPLVVAAGLLTSIAVIFGGTGVW
                     DQTDTFWGVLRMIGQTGLQFIVPMISAYIAYSIADRPGLAPAFITGMMCQNLGMGFIG
                     GMVAGLACGYLANALKKVKVPMQVISLKSIMLIPFVTTLVVGIILWYVLATPIQAMTT
                     GLTNWLEGMSGANAALMSAILGGMMAFDMGGPINKIAYAFGVASFSSGSFGPSTAMLL
                     GIAIPPFGMFLATILNKKLYDESERDNAKTAMIMGLVGITEGTIPFAVKDPLRVIPSI
                     VVGTAVACGLNGFFGVTQETMLSTFMAIPFVTNIPLYLVSIVIGGVVTALMVNALKSI
                     KYKKEQQVNSVEEGK"
     gene            complement(37641..37955)
                     /locus_tag="RD451_001540"
     CDS             complement(37641..37955)
                     /locus_tag="RD451_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HDT7566807.1"
                     /translation="MTKIVAVTACIAGIAHTYMAKANLEKFAKKKGLDIKVETQGAMG
                     IENKLSISDVSEADVVIFAVDTNVSERGRFDGKPILTVGTSEVVKDGEETIDEAIALI
                     NK"
     gene            complement(37971..38417)
                     /locus_tag="RD451_001541"
     CDS             complement(37971..38417)
                     /locus_tag="RD451_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDT7566808.1"
                     /translation="MISEKININNIVIDLNASDKKSVVEKLSKLLETNGFVSDHKQFQ
                     KDVFDRENHMTTGIGKNIAIPHGKSLAVIESTVAVAKLKRSVEWGALDDQPVDLVFLL
                     AIKDTDKGTNHLRILAELSGRLMDDEFVKRIKDSRNKKELVKALSF"
     gene            complement(38418..40340)
                     /locus_tag="RD451_001542"
     CDS             complement(38418..40340)
                     /locus_tag="RD451_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDT7566809.1"
                     /translation="MGIEFSERQMKILYFLIENEHTTYKELSEQLYVSTKTISKDILI
                     LKEIIQKMPDVQMLVQPKKGVSLIGKKETLRNLLSSHKINIADSPEDRLTYVFAKLLN
                     TNDSLKIQNLADELYVSRSTVESTMKDVRKRLNKHGMSLVSDRNGVRIKADEKSKRRL
                     MSEVVNYYWGGFTASNSKTDLLDLNINFIGEANNFLNKDILKKVAELLNRYMNKTQLK
                     FTDYEFQTLAIHLAIAIERIETSNFLSRSNNSEEEISKNTLILIKMIEKAFSIIVPID
                     EQAYVDIHITSIEKNAMNHDLDQTKLSYLDMGVELQELVRIKLNEFYPDEELINNLVL
                     HLNAAVKRLKLGVNIYNPYTDKIKYSFKRSFMISVDLLEEIEERFCIHFNEDEIAYVT
                     LHIQSLLDRYKPDKTKVILVCSSGYGTSKLLEQRINNGFADMVEIEDVLSINELQDRK
                     VTDELVISTIPIENTNFPVIVVSPLMLGADVRKVKQYLQLNEQTEDAFLNLLDKRFCF
                     FTHQIKDNQVNVLNIITKKLVKENYAKEGILEGAIKREKLSSTAMNDFAMPHIEVDFI
                     KKPVICVYVNPEGIDWDGTLVHSVFFFALNEKVKPELNKIYETFNEIASNHELLANLK
                     TSSSFEKLVYILKEGL"
BASE COUNT        12276 a         8197 c         6956 g        13043 t
ORIGIN      
        1 tactcctatt ctaacatatc cgaggctgta aaagactttc tttacaaatt cttcaagaaa
       61 ttctgctatc ttaaagtaaa ccattaattc gttctttttc caaacgactg caagttgtac
      121 aaaaaaacta ttttttacat gactttactc gtcaaaacaa gtagaataga acgaaattaa
      181 tgagtggata tttgattgag gtgtcacatg cgtaaagaaa ttaaaaatgc aaaacgaatt
      241 attgtcaaag taggaacaag tacattgatt tatcccaatg gaaatatcaa tcttgcggca
      301 atcgatcagt tagcttttgt cctttctgat cttagaaatc ggggaaagga agtgatctta
      361 gtctcatcag gagctgtagg cgttggtatg cataaattac atttgtcaga acgtccgact
      421 ttgattcctg aacagcaagc tgcggcggct gttggtcaag ccgaactgat gaatatctat
      481 aatcaaagat tcagtgtata taatcaacag acggcacaga tcctcgtgac aagagacgtg
      541 gtagattatc ctgaaagtcg taaaaatgtg aggaatacat tggaacagct tttgattatg
      601 gacacgatcc ctatcgtgaa cgaaaacgat actgtagcag tggatgaatt agatcatctg
      661 acaaaatttg gcgataatga tcagctgtca gccatcatgg caaaacttgt cgcggcagac
      721 cttttgatcg tcctttctga tatcgacggg ttttattcag ataatccgac tacaaatccc
      781 gaggctcaga tgtatcgcta tatcgataaa atcgatgaaa agattctggc acaagcaggt
      841 ggtgctggta gcacatttgg aacaggcggt atgcagagta aattaaaagc cgcttctagg
      901 atatttgaag caaacagcgc aatgatttta gcaaatggaa aaaatccggc aattattttt
      961 gatattcttg caggaaaaga agtaggtact ttatttaagg aggacttgaa atgactgact
     1021 tgatgcaatt aggacaacag gcaaaagata gcgcgcaaca actagcactt atgcctacaa
     1081 accgcaaaaa tgagctactt gttcaaatgg cacaaaccat caaaaagaat caacaagcga
     1141 tcattgaagc aaatcataaa gacttagaaa aagcagtcga aaacaatatc agtgaaacga
     1201 tgcaagaccg cttgcagctg acacctgagc gaatcaatgc catggctaca gagatcgaaa
     1261 aaattgcttc gttagacgat cctattggaa aagtagatga gatgtggacg aacaccgacg
     1321 gattgagaat cggcaaaaag cgcgtgccac taggcgtgat cggcatcatt tacgaatctc
     1381 gtccaaatgt cacgacagat gcagctagtc tagcattcaa atcagggaat gccgttatcc
     1441 ttcgcggtgg caaagaagca ttcttctcga atcaattatt agtccaatta ttgcagcaag
     1501 tactggtcag tgctggcgaa tctccttatg ccatccagtt tgtcgatgat acttctcatg
     1561 aaactgcagg acagttgatg cgattgacag aatacttaga tgtgctgatt cctcgaggcg
     1621 gagcaaaatt aatccaacga gtcaaagaac aggcaacggt acctatcatt gaaacaggta
     1681 caggaaataa tcacgtatat atcgataaag aagcacagtt atctatggca gtgaacatca
     1741 tcgtcaatgc aaaagcttcc cgtccatctg tctgtaacgc ggcagaaaca ttgctgatcc
     1801 attctgagat cgcacctttt ttcttgccag ctattgaaaa agaactggta gaacacgggg
     1861 tctctttacg tgcggatgct cgtgcgttag aatatctaga gacggctgct ttagcagaag
     1921 acacagattg ggatactgaa tatctagatt atatccttgc tgtcaaagtg gtcgattctt
     1981 tggatgaagc aattgcacat atcaatcggc ataatactaa acattcagaa acgatcgtga
     2041 cagatagtta tgcggctagt caacgtttct taaatgaagt ggacgcggcg gctgtctatg
     2101 tcaatgcctc cactcgtttt acagacggat cggtatttgg ttttggtgca gagattggta
     2161 tctctactca aaagttgcat gcccgtggtc caatggggtt aaatgaatta acttccacaa
     2221 aatatatcat ttatggcgat ggacaaatcc gcgaataatg tttcgtgtga aacattattc
     2281 ccgccttttg ccttttttct gtaaaggttc tatccaacta gaaaggtgtc aatatgtttg
     2341 aaattttaat gatttttttt atttacctta tttctctgaa tatcgctgct tttctgggag
     2401 tcggtatttt atcccttttc tttcaattca aaaaacgaag catagggagt caacgggaaa
     2461 aatggtcgca gtattttgac aaaatcgggc aaaaagggct ggttacacgc ttgcacatta
     2521 gttacatggt tgcattatgc ttattagcga caatcaatta ctattctttt ttcgatcatt
     2581 caatcgctta tacgattacg ctactgattg ctgggatttt tcacttatct tataaatatc
     2641 agctgaataa aaaccacttg aatcggactt tccgctaaaa aatatccgta cgataagtag
     2701 agtgccttga agatcggcaa aaaactgccg gactttttag aggctgtgac aaagattttg
     2761 tcacagcctc tttttccata taaacggcgt tcgcctacca gctgcctggt aaatctgttt
     2821 cctcttcgtt aagaagcgaa aatccgtcaa atgtttcgcc atcataataa cgaagcagct
     2881 catccatgga caagttcatc gttttttctt tttcttcttc cgctgattca gccagtagct
     2941 gttcccgata cacctgatac ataccagcta ttttttgctg catcgctttt ctagtttcac
     3001 cttccgcatt gattattggc aattctttga tatagccacg ataaatcaac cgatcatctg
     3061 aaaattcaat gggtaattca acgagtgtca acccgacttc ctgaaaatat tcttccagca
     3121 tctattatcc ccccattctt tttcttaaat gaattttagc ttacctactg aaaattttcc
     3181 agtttcatta ttttgagaaa aaaagggaat gtgacaaaaa tcgtgtcaca tccccttttt
     3241 ccgaataaat ggtgttcttc tgccaactcc tcaatcataa gtcacaatat tcaacaaaca
     3301 tgagaaactg ttttttgaaa ttgttccttg tgattcagag ttaaacgaca gtctcacaac
     3361 ctcttggtaa acggcgttca atcagctgac cctcggtatt agctcaaaaa acggtaaaat
     3421 atgagaagct atttttccgt tttgtttctc taatacttag gataaaacgc tgattttaca
     3481 acctctgtta aacggtgttc aatcagctgt ccttcggtat tagctcaaaa aacggcaaaa
     3541 tatgaggaac tatttttccg tttgtttctc taatactcag gacaaaacgc tgattttaca
     3601 acctcctgat aaacggtgtt caaaagcttg catctgcggt aataagccca accaaacgaa
     3661 aaatatgaga agctattttt gtttggctgt tcttatgact tgatgcagga cagctttttc
     3721 acaacctctg atttcttatt cttcttcatt tgtagcaaaa taattacggt gataaatgat
     3781 acaacataca ctgataagaa caatggcacc tgcaaaataa aacgcatagc tttcaccaat
     3841 atgttcacca atcacacctg caataaatgg tgctaaagct ccaccgaaaa agcggacaaa
     3901 actatagctg gacgaagcaa cgtttcgttg cagacctggt atttccatag caatcgtcgt
     3961 caacagtgta ttgataattc cttggaaaaa tcctgctaac acaatgctga tcggtacaag
     4021 gactggcata gaagttccag ctcctaataa cagcaaacaa ataatgaata agacaaatgc
     4081 tgctaaaatt gtccgataag tcgtaaactt ccgctcaaga gccggtgcaa cgaaaatcga
     4141 agcaatagcc agaagcacac cccagccaaa aaatacaaaa ccgacttcta attcagaata
     4201 gccaatcaat aaaaatggcg catacgcaag taaagtaaag aatccgaaat tatataacaa
     4261 tgcgattagt ccaactgaac gaagtttatg attgcttaac gctttgacac cttcccaaag
     4321 gcctactttt ctctttggtt tctcagtttc aggtaaaagt accgctaggg ctataaaacc
     4381 gcaaaacatc aaaaatgcta ccccaaaaaa tggataacgc catgaaccac tgcccaagac
     4441 cccaccgact agagggccaa cagccattcc gcagccaagt gctgcttcat acatcatgat
     4501 tgctttttct gtgttaccaa ctaaaatact gacgatcgtt gctaaagcag tagagacaaa
     4561 taaagcattc ccgacacccc agccggcacg taacccaatc agcattccga tattcccaga
     4621 taatccgcca agaccagcga atacaacgat gataaacaat cctgtcatca atgttttttt
     4681 caaaccgatc cgactagata agaaacctgt aaatagcatc accacaccag tgactaacat
     4741 gtaactagta aataacaggg tcgtttcagc tggcgtagcg tttaactgtg cagcaatcgt
     4801 ttttaagatt gggtctacta gacccactcc cataaaagcg atcatacagg tagctgctac
     4861 aactagcgct gaacttttcc cctttgtttc ttcatttgtt tgttcttgta tatctatttg
     4921 attctccaat atttccatcc ctttctctct attagcatca tacatgattt attttacatg
     4981 tcaatatgca catgtaaaac gtggaaactt tactgtgata taataaagaa aataagacga
     5041 gaggtaggat ttttatgaat actttagcct atatattatt atgcgtgctt ttatccaaac
     5101 cacgttctgg gtatgaattg aagcagctga tcacaatttt ttgggaagcc catcacagtc
     5161 agatctatac aacgcttgcc aagttagacc agcagggtta tgtgaccgtt ttggacaaag
     5221 acgagcactc tcaaaaaaag atctaccact tgactgatga aggacgtgct cttgtagagg
     5281 aatggatcaa agaggaaact cccgctccta cgcaaaaaga tgaatttcta gcaaaaatct
     5341 atgctttttc gacgctcgat aaaacaacag ctactggact gctattcact agagaacaac
     5401 agctgaacaa aatcatgcaa aaaaatcaaa aaaaattgaa tgacctctcg ctagacaaga
     5461 aacaagaatt tggacgttat gttgtgatcc agcgcagaat tatgctttgt cagcaggaac
     5521 tccaatggtg tcagcaagta agagaacaaa tgcagcagtt ttttgagtaa gggataaaca
     5581 gaacctttct agaaatatct attgaagagc aaattatctt caataaaaga gcaatacagt
     5641 tggaaaagaa aaagcgatcc gaacgacagg ccaaaaccta tcgttcggat cactattttt
     5701 ctagaactgc attcaagaga ctatgacaaa aagcatgcca aggccttttt tcaaataaca
     5761 gtgttccatc attcattact ttgaattgct tttagcacac ttcttgaaag cgggccaacg
     5821 atgatcaact gcaacggtaa agcggcaatc acattcattt tccaagcatt catataagca
     5881 gagaataatt gatcaggtat tccttgttcc atgatcacac cgaataaaga catacatgtc
     5941 accattccta aaaccatcaa gcatgaaata gttaagatca tttggacctt gctttctgga
     6001 tttactggta gtttaaaggc aatttttttc gccagcacac cgatgatgaa gacatccaaa
     6061 atgaaagcca ccacgaatcc aggcactaga ccaatcaaca aacttgataa atgaagatct
     6121 tgatgcagcc ataaattata cgcgctcatc cccaagacca tcaaaaaaca catcattgtt
     6181 gtaaaaatta ttccttcttt tttatttgta ggcaatctgt accactcctt taaatttgtc
     6241 acgaaaatca tcgtagcaca tttaaaaatt tctcgtaagt acttttttta ttttctgccc
     6301 ttttatttca taaacttcat cagccgtacg ctcgacaaag taagaatcat gagaagtaaa
     6361 caaaatcgtt cccggatata tttgcattag cttctctaaa gcttcgatcg ttgccatatc
     6421 aataaaatta gtcggttcat ctaacagcaa cacattactt ggcttagtaa aaagcaaagc
     6481 aatcgtcaga cgggtcgctt ctcccccact taatgtacat aacggtttcg tcaaagtttc
     6541 ctgagcaaac cctaagtgat tcagcaaact acggacaagc gattctgaaa actctgtttg
     6601 tctcatgaca aaacgaatga tggattcttc agatgtcatt tgataaccct tttgctgata
     6661 tacttgaaag cttactttcg gagagagaag gattccttct ccttgtttgc ggatatgttc
     6721 taataaggtt gtcttacctg aaccattttc accgacaatc gcgatttttt tacctaaaga
     6781 aaactgaaaa tcaccattta ccagtaatgt tctcccactt ctttccaatt ggacattttg
     6841 tcccatgatg ggatagcggc tgtggagttc aagagatttt ggtactggaa aacggatttg
     6901 tttcatctgc tgcggcttgg ttgtttctcc tattttttgg agtcttctct ctaatgtttt
     6961 cgcattcttt tggatggctt tttgtacact gtctttttgt ttagaggaag acaaccgatc
     7021 cagtctgatt tgttgctttt tctttttact ggacactttt tccaactttt ccgcttgttt
     7081 tttcttttct tggatcgatt tttccaatcg ttttttctct ttcatgatcg actctgcttc
     7141 tcgtagctga gtctttttct ccaattcctt ttgagtgaga taggcactat aattccccga
     7201 aaactctcgg atttctccgt cttttacttc ccagattttc gatgctagct catctagaaa
     7261 atagcgatca tgactaacaa aaaccagcgt accataataa taacgaagct cttcaatcag
     7321 tcgatcaata ctttttctat ctagatgggt tgttggctcg tctagaagca tcccttgttc
     7381 ataagaagaa agaagacgta tcaactcgat ctttcgttct tcccctccgc tccatttccg
     7441 ctctgaagtt tcttccagtc ttaactggaa atgactggct aattccaaat ttaggtcctt
     7501 tgcttcagcg agataggtta attgaggcag gtagttgaag gtgatctctg tttggatttt
     7561 cccatgatcg ggaaaaagtt caccggctat tagtttgagc aaagtcgatt taccgacacc
     7621 attttctcct atgatcccta tacgatcttg ctgatagaca cgaagagaat caatagatag
     7681 ttctagctgg ttgccaaagc tgacttgtag atttgttata tttactgcta aattttccat
     7741 atgttttaca ctcctatttc atgtaaaaca acaattatcg atactaaaaa agagcagaaa
     7801 aatctgtttg caaaaaaact gcatcacatc ttttcctact ctgaacgaaa taactatgac
     7861 taaatcacca aatctgtcat agctttcacc tattctactg tcgttcgaaa aaatggacat
     7921 actccatcca tgaaattgtt gtttatacat gtcttttgaa tttatttagt tgttattcaa
     7981 aagttcgaaa cgtaatttca tcgatgcagt catttttccg acctcctttt ttattaggtt
     8041 accacacacg attcaaaaaa agcaatagct actgaatagt aactgaaaac cttttattcg
     8101 aacatagtga tcttttctgg tgctaaacga acagactcgt aaccttcttc taccgctttt
     8161 cctattgata aaataataac tggaacataa cggtctttat ccaaaccaaa tgcctctgcc
     8221 aactgatctg cttcgaatcc accaattgga tttgtttcat agccatgatc acgcgcaact
     8281 aacatgaatt gcatagccgc taagctagaa tcgactttga ctacatcgtt catttcttct
     8341 cttgaaaaac tcttgtaata aggaatgatc gcagctaatt gttgatctct gacttctttt
     8401 ggcatcttcc ctgattcgta agcttggttg tagatttctt cgccatattc gtaacattgc
     8461 atatcgccaa aaatcatgac cattgcagaa gaagtatcat tttgtctcgt attgaaacgg
     8521 atcaaaggac gcaagatttc ttttgcttcc tcgctttcag cgaccacaaa gcgccatggt
     8581 ttcatattga cagaagaagg tgcagtcgtc gcttctttga tcatttccag catttcttcg
     8641 tgtgggattt tgtatgtttc atcatatacg cgaacggatc ttctaccagt cataattgtt
     8701 gaaaaatcat ttttttgttc cattattatt aacctctttc gtttctgttg ttatattgca
     8761 aagttgggta ttcaatttat ctaaaagtgt tagaaattgt ttcatttcta catcgctgaa
     8821 agccggggat agcacggaac ctgtatcttt atggtccatt tcacaatgct tgattttctt
     8881 ctgggctttt tctgttagcg ctacatacac ttcccggttg ttctgaggat ttctctgacg
     8941 cgaaacatag ccatttgctt ccaatacctt cagatgacga gtaactgctc cttgatcaat
     9001 ctgcaacttt tcttgcaaac tgctttgtag caatggattt tcttctttca gtctcatcat
     9061 gatctcgtat ctagtaagac ttataccgat attttcttca aagatctgga cgattttttg
     9121 atcggctaat ttgatttgat ataaaaggtg actaatctct tctaaagaca taatttcctc
     9181 ctttctaata attgactcgt caacgattga cttgtcaata atagaataaa aaaagaaaaa
     9241 agtcaaagaa tcagctgtgt aataaaaaaa acgctctcaa tagaaaagta tagagaaaag
     9301 aaattttttg tagaatgaac ggaaaaaatg ataaagaaag cacaacgcta aaaccaagat
     9361 tattgattct tatcaaacta tagaagatag ctcttctgca gtagataatt ttacaccgcc
     9421 aaaaatttcc gaaatcgcct tttgcaagaa tcccgtcgaa tattagaaat tggatcagta
     9481 tgcttaaaca gtaataaaaa agttatgaca agatgttgtc acaacctttt ttgagtaaac
     9541 ggtgttcaaa aacttgcatc tgcggtaata agttcaacca aacaaaaaac atgaaaatct
     9601 gtttttgttt ggctgttctt actacttgat gcagggcagc tttttcacta cctcttttta
     9661 ataaccataa aatcctattc cttcatatct ccagcccatc ggtgttagcc aatctctttc
     9721 cttagcactc aaggtatagt gatgggtacc agttttttca tttggattaa atagtcgata
     9781 aattggcttg gaaccaccag aataaaaact tagaccttca taacgccaac cgatttttgt
     9841 taaagagttg atctcagatt gtgccattgt gtaatgatgg tctccactgt aaggattgta
     9901 taaacggtag acaggttgtc cgctgtttgg tgcttgccaa gcaatccctt catattccca
     9961 gcctacagtt ggcagataat ttttttctcc ggcattcaat gtatataaat gttctcctgt
    10021 atgacggtta tacagacgat acatcggaga agttgaagtt ggtgctgtat catactgtgt
    10081 cagattatag gtttcgatta cattgttcaa tgtagaacca taattaggcg cagtggcata
    10141 acgacctgtt agccaagccg tagcatcttt gtaagagttc gtattgcttt tccatgcacc
    10201 ggaatagtag taaacgcctg gctgaaaaga agtcgtcttc aataccgtta cgttatcttg
    10261 caatgattct ttgtacgaag gatattttct aaaagcggca ttcaccgtaa tccattgccc
    10321 attcacatat tccgaagtag gcatcgtaac agattggcca ttatagcttc ctttaatccc
    10381 aaatagattg taattagggg cagaagccaa agtactgttc ccccagccac tttcaacgat
    10441 ggcttgagca atcatgactg atgcatataa gtcattggca cttgccaaac tttgtgcagt
    10501 tgaggcaata ctatcaatga acgcttgttg agaattagca gatgagcgag cataaaaagc
    10561 atagccagta tagttttcga attcagacaa atctgcttga tgggtatgtg tcaatgtttg
    10621 cccatctgtc aattggttcg tgatttcttc tgcattctct ggattgttct gagcttctgc
    10681 tgatgtactg tcttcggttt gtgtttgttc tgttgtttca gttgttggtt cttcggttga
    10741 aattgtattt tctgagacag tagctgactg caaagtactt tctgtatcgt tttcaattcc
    10801 tgtttctgaa gaactcgatg tctgagttgc gacagtttct gtcgattctt cagctagcac
    10861 tgttgtgttg gcaactgcta gatttcctaa aagaataacg ctaaataata aattctttgc
    10921 tttcatcttt tttctccttt gaattatgaa acttttccta aataacagtg taactaaaaa
    10981 agtaaaagca agtcaatgtc catatttaaa taacatttgt ttctttttaa taaatttgct
    11041 ttttctgcat aaaaagacgt aaatgaagaa tattcttctc cattcacgcc ttaaattgat
    11101 ggtcgtttga ataactattt aacaagtaat tctctctgga tattatccgt tatggattat
    11161 acttcctgtg tcgtcggacg gataatcatg ttgctgacag acatccggtc tggcgtttct
    11221 atcgcaaatg ctacagcaga agctatatct tcagatgtta atccccattc tttttgcgct
    11281 tcatgaagtt caagagcagc ctttttgtcg ctgatggttt gatataattc agtttgaaca
    11341 gctcctggag agatgatcgt agatttgatg ttattttgcc gttgctcttg acgtaatcct
    11401 tccatgattg cacggacagc aaattttgtt ccgcaataaa cggcggaatc aggataaaca
    11461 acatgtcccg ccacagaatc agttgaaatg atatgcccag atttttgttt ttccatgatt
    11521 ggaagtacgg cggaaattcc atttaacaca cccatgatgt tgatatcaag catattttgc
    11581 cattcatcac ggtgaccttc aactaatgga gcggttggca tgattcctgc attattgtac
    11641 aatacatcga ttcgaccgaa cttttccatc gctaaatcga taactgcttg gacttgtgca
    11701 aaatctctta catctgctgt ttgaatatat agctcagctt ctggtaaaga ttcttttatt
    11761 gcttttaggc gatcttctcg gcgtgcagct ataactagtt tagccccttt ttctgctaat
    11821 agcttcgttg ttgcttcacc gattccgctt gaagcgccca tgatgacaat cactttttct
    11881 gataaatcat tcattctatt ctcctcctgt tttgaaaaat ctcttgctta tactcactat
    11941 ctcttatttc atcttactgt tcaaataatc cgttcgacag gtttgacgat tttggcaggg
    12001 attcctgcaa cgatggtatt gtctgggaca tctttcgtaa cagttgcatt cgctgcaaca
    12061 atggcattct cgccaatcgt tacgcctggc agaatagttg ctcctgctcc gatccaagca
    12121 tttttcttga tgtggattgg ctttactgac aagcctcttc gttcttttgg atcggttaga
    12181 tggttcaccg tgatgaggtt gacacgagga ccaatcaata ctgaatcttc taaacagatg
    12241 ccacctaagt caacgaacat cacttgacga ttgataaaga catttttccc tatactaata
    12301 tgtttgccga aatctgtata aaaaggcagc agaacagtca ccgtatcatc tactttgtca
    12361 ctaatgatat tttctagccg tttgcggata tctgctggtt catggtaccc agtattcagc
    12421 gctgctaaag gctcttcgtt ttccgcttgg atctgatgga tcacttcaaa gagcggatcc
    12481 gttactcgaa tctctttatt gacgatttgt ttttcgatga ggcttgtcat tttgctccct
    12541 ccttttatcc ttactttata acggacggct tatgatgtct aatacttata aaacatactt
    12601 aactattcct tttaactata cttagtggta tgctttttta aaaacaggag ggaaaaaatg
    12661 gatattcgta tactgacgta ttttttagca gtagctagag aaaaaaatat cagccgagca
    12721 gcaaaatctc tgcatatcac gcaacctact ctctcaaaac aactgaaaga tttagaagaa
    12781 gaacttggtg tgacactttt cactcgaggc tcccgagaga tacagttgac ggattctggt
    12841 cgatatcttt attcaaaagg aaaagaaatc ttgtcgttgg tagaaaaaac ggcgaacaat
    12901 ttaacaaatg acgcaatcat ctctggagaa atctacattg gcggaggcga aactaaagca
    12961 atctctttca tttctgatag ccttcattcg ttgatcaagg cgcatcctga tatccagttt
    13021 catttatata gcgggaatgc agatgatatc atagacaaac tggatagcgg attacttgat
    13081 tttggactcg taatcgaacc gacaaacaaa caaaaatacc agtcatttcg actgccagcc
    13141 caagatcgtt ggggactttt gatacatcgg aatcatcctt tagcaaagca aacagtcatc
    13201 catccgcagg aactgaaaac tgttcctttg atcatttccc ggcaaacgtc agtggacagt
    13261 caactagctg aatggctagg tttcagcata gatcagttat cgatcgtcgg aacatataac
    13321 ttattgtaca atgcttcttt gatggtcgat aacgggactt ttggtgcatt agctctagat
    13381 gggatcatca atacttatgg gacggaaaaa gtattcatcc cactcgatcc gccattacaa
    13441 gcttcactga atctcatttg gaaaaaagac cagcctcttt ctcctgctgc tcgtaaattt
    13501 ttagatgtcc taacggagaa atacagttaa gtagagtttt tttccttcgc tttcagcttt
    13561 ttaacaacga ataagttaag caaaagatcc aatgattaaa taacataagt ttcttaattt
    13621 gttccttcct tttatttctg ataattccag taaattacta taattataaa aaaagaattg
    13681 acaaaacata actgtctata taaaattgat tacgttaaca ataattcgtt tcatgtgact
    13741 agatcatact aggcatgaaa aatctctgag gaacatggtt tccctaggag gtttttcgtg
    13801 tctatttttg tttggccgca atcaactggt ctagcaaacg tgaaaaccaa atcttcaaaa
    13861 agggtgcgcg catgaaaatc aaaaagatct ttaatcaaaa tgcagtattg gtagatgacg
    13921 gtggacagga aaaagtagct attggaaaag ggattggatt tgacagaaaa agaaatgatt
    13981 tgatttttga tcgtgatgtc gaacggatat ttgtcatgga accagaaggt caaatcaagt
    14041 tgcaaaattt acttaatcag attgatgaac gctttttatt tgcagcagaa acgatcattg
    14101 atcatgcgga aactgttttg atggaaaagt tgaatgaaca tgtattgatc gctttgaccg
    14161 accacattgc tttttctgcg gagaacatta ataacggtat cgtcatccgc aacaaacttt
    14221 taagagaaat cgaagtgctt tacagtgatg aattcagtat tgctcaatgg gcagtagagt
    14281 atctgacaaa agagcttggg attccatata cttatgacga agcaggatat atcgcaatcc
    14341 atattcacag cggacgaagc ggtcggaaca ataaccatcg cagtatccgt gaagtgacga
    14401 ttgtatctga catcatccat ttagtggaat cagaattgga aacagatatc cattcagaac
    14461 cattttcact gaattattca agactggtga atcatttacg actgcttcta caacgaaccc
    14521 atgcgcaaca atatgctgtt ttagacacgg aaatcgtaga aatggtcaaa cgaaaatacc
    14581 cagaaagcta taagatttct aaaaaaatcc gtgtgttgct gaccaaagaa taccagctcg
    14641 cgatcacgaa agaagaactg ggttacttgg ccatccatat cgagcgttta agaagcgcaa
    14701 tcgtacaaac aaatgttaac aatcatgagg aggaaaaaaa ttgaaagcat atctacaacg
    14761 aatgggacgt tcccttcaac ttccagttgc ggtcttacct gctgctgctt tactagtagg
    14821 gatcggaaac tggtgggcat cttatagtaa cgacattgtc gctcattttt tacaagctgg
    14881 cggtaacgca gttttaggtc aattaccttt gctgtttgcc gttgggttag cactagggat
    14941 gtcagtggac aaatcaggtg ctgctgcctt ggcaggtttg gtcgcatttg aagttccagt
    15001 aaatgtttta aaaactgatt cagtagctac tttattgaat atcaaaccag aatcagttga
    15061 tccatctttt gctcagatca gtaacgtatt tattggtatt attgccggat tgattgcggc
    15121 agctctttat aatcgtttcc acgaagcaaa attaccgatg gctttatctt tctttagcgg
    15181 caagcgtcta gtgccaatct tggctgcctt tgtcatgttg ctgatcagtg cagtgctact
    15241 gctcgtatgg cctccggttt actctgcttt agtttctttt gctaaattca ttttgagttt
    15301 aggctggggt ggtgcaggtc tttatggctt cttcaaccgt ttactgatcc ctacaggatt
    15361 gcatcaagca atgaactccg tgttctggtt tgacgtagca ggaatcaatg atattggtaa
    15421 atttttggct tctgaaggaa caaaaggcgt aacaggaatg tatcaagctg gatttttccc
    15481 aatcatgatg ttcgggcttc cagcaggagc atatgctatt tacagaaatg cacgtccaga
    15541 aaacaaagca aaaacagctt ccttgatgtt agcagcagct tttgcttcat tctttactgg
    15601 tgtaacagaa ccacttgaat tctcatttat gttcgttgct tggccattat atgtcttgca
    15661 tgcaattttc actgggattt ctttagcagt gagtgcattc ttccattgga cagcaggatt
    15721 tgcctttagt gccggatttg tcgattactt cctatctttg aaaaatccga ttgcgaatca
    15781 gccattgatg ttgatcgtcc aaggattagt aacagcagtg atttactact ttggctttaa
    15841 ctttgctatc aaaaaattcc atctgatgac tcctggccgc gaggaagcag atctttcaga
    15901 tgacgatact gcaacgacta attcagacaa taaatatgcg gcacaagcaa gcaaaatcta
    15961 cgctgcatta ggcggagccg acaatgtaac ttcgatcgat aactgtacta cacgccttcg
    16021 tttgcaagtc aaagatacag gcctgatcga tcaaaataaa atcaaagcca ctggcgtacc
    16081 tggtatgaag atcatcgacg gaaaaaatgc gcaagtcatc gtaggtacag aagtacaatt
    16141 cgttgcagat gagatggcaa aactacatgg tggtgctgca acacgacctg cacaaacaaa
    16201 caccgtggtt aaaacagaaa catttgccgg tggaacgatc gaacaagata tttacgctat
    16261 cgcaaatggg aaactgattc caatcactga agtttcagat gatgtattcg cggaaaaaat
    16321 gatgggtgac ggctatgctg tattaccaga aaatggagaa atcttctctc caatcgctgg
    16381 tacgatcaca aacattttcc caacgaaaca tgctgtcgga atccaaacag atgctggtat
    16441 cgaagtcttg cttcatatgg gcatcaacac tgttgactta aaaggcgaac cattcacttt
    16501 atatgtaaaa gaaggtcaaa aagtcgcaag aggtcaattg attgctttag ttgatcttgc
    16561 cgctattcaa tctgcaggca aaaacacgga tatggtcgtt gtattcacaa atggcgacaa
    16621 agtccaaagc ttagaaatcg aacccgcacg tgatgtaaaa gcaaatgata aaatcggctc
    16681 tgtttccaac aaagcctgag ccatcgtctt ccccagactt ttttatcgat aaacaaacag
    16741 gagctgagac aaaaatcttg tctcagctcc tttttccgaa taaaaacggc gttctcctgc
    16801 caactccgcg gtaataagtc cagccaaacg taacatatga agagctattt tttatttgac
    16861 tcttcttatt acttgatgca gaacagcttt tttacaacct ctgataaacg gtgttcaaaa
    16921 accagtttat cggtatgaag tcaaatttat gcaaaaatgt ggaaagccat tttcacaaaa
    16981 tttttcttca tactcaaaac taatcggctt tttcacaacc tctttataca ttattcctga
    17041 tccaatattt cttttaatgc tgcttcaaga gaagttaatg gttttcccaa tactttttct
    17101 aaatcatcag aggaaatagc taactgatcc tttttaatat catgttggat cgctaaaaac
    17161 atgtcagctg cttcttgagg gaatccggct tcttttagat tttcgacaaa cgctgcatca
    17221 cttgcttcaa taatttctaa ctttttacct gtcgcacgct ctaatgcctt ggctaattct
    17281 tcatagtcag ttagattgcc ggataattct aagatttctg gagagtcact ttctactagt
    17341 acttttgctg cagcttctgc atattcacgt ttcaatgccc aacctgtttt tccatttcct
    17401 gcagcataaa cgaattgacc agtttttaaa gcctgcccaa tgataggtaa ttcattctct
    17461 acataccaat tattccgtaa aaatgtatgg gaaatacctg aatccttaat cattttttca
    17521 gtgaattggt gatctggcgc taatacactg atcgagtgat cggcatctgc aaaacttgta
    17581 taagcgatat aagatacccc agctgcttgt gctgccttca ctacattctt atgttcggct
    17641 tgacgatttc ctggaacgcc agagacaaaa agcaatcgat ctattccttt caacgcttct
    17701 ttcattgagt ctaaatcatc ataatcacca atacgtatat taaatccagc ttctttcagt
    17761 gcttctcctt tttcttcact acgtactagt acatagattt cattttgtgg aaccatcttt
    17821 tttaagaatt ccagcgcata accaccaaaa cctccagttg ctcctgttac taaataatgc
    17881 atatttgcca ctccctattc tttttatttg ttaagattta cagctgtaca tttataaatt
    17941 acacctttat cataaagagt gtggtaagat aagtcaagca aaaaaaatga aaggatgaca
    18001 actgatgaag tattctctgc aatttagtga tgcaatccat gtacttgcct atattgaaat
    18061 gtttcaagat acccgatcac tttctagtga gatgattgcc agtagtatcg aaacaaatgc
    18121 agcaaatgta cgtaaaatca tgagtcagct caaaaaatcc ggtttgatct ttacaaaaac
    18181 cggaaaaccg cagccttccc ttgccaaaag tccagatcag atttctttac tagatgtcta
    18241 tcgcagcatc gaaggtaata cacagcttat ccaagtcgat ccaaaaacaa atccaaattg
    18301 cgtcgttggt gcgaatatcc aagaagcttt agaagaaagc tacgctcggc tgcagaaaaa
    18361 ggcagaagaa gaaatggcta agatcacact tgatagtctg atacataaaa tagccgtttt
    18421 ggaaaaagaa aaaagaccag aaaacacagg cctcgtagag agatttttat aattctctct
    18481 actgtgcctg catttttctg atcggaatcg tctacataaa ttcttttatt ctccggggga
    18541 caaaagcctt gtcatgcccc tttttcctct ctaatgctca ggtcaaagcg ctgaagtcat
    18601 gacgtcttga taaacggtgt tcaagtagct gaccctcggc attagttctg aaaaatgcaa
    18661 aatatggaaa gctatttccc atttttcctc tctaatgctc aggtcaaagc gctactttca
    18721 cgacctctat attatcatgg tttattgact accggtatcc agatttctcc catatatttc
    18781 ccgttggtaa ctcccatttc gactacagca tttggacccc caacataggc gtaatcttct
    18841 acttctctta aaacatgccc aaaggccgta ttcgtcaaat catttcttaa ttcttcaggc
    18901 gattctgcta aagcgattac aacaagatac gttccttttg ggaatgggat gattcgggta
    18961 gtgtttggaa catcctgact cgtttgaaca ccgacatagt acatcatttt cccgttatag
    19021 ggttcgttga ctgtaaagaa ataatgattt tcagcagctt gtttcaatgc atctattgtt
    19081 ccattaccga taactttttg ctcaaatgct tgtttctctg cagccaaacc gacaaaatcc
    19141 gtattgctac tcttcaattc cacaccaata cccgtcaccg taaaatctgg tttttcttcg
    19201 atcctatact ttgccatttc tcccaccctt tctattatat taagttcatc ttacataaaa
    19261 ttaaagggaa atgacacgat tacgctcttt tttctaggga tatttttatt ttttaactat
    19321 ttttttgctt tcactgcaat ccaaatctca ctgtaaacat tactgaaatc ctctccccat
    19381 tttgtaaaag agatctcggg agcttcgact aactcataat ctgaagaagg aagccattct
    19441 gcatagattt tcccccaagt atcttgtaaa gtttggggaa atggcccttt attaggaaaa
    19501 atggcccaag tgtgttcttc tatagcaagc atttctaaat cagcgtacgg attttctttt
    19561 gtcgtagcaa agccaatcat gtgcatcaaa ctgccctttt cttccaagcg ggctccatca
    19621 aatccataag aaacgttgat tacttgattt ggatataaat ctcctaactt atgcatctct
    19681 tccctttgag tctccgtgat cgtctgcgct aacttttgta tttcttgatt gactccttca
    19741 aatttgacag gaactttttt cgccacacct gccacataaa actgttcttt cttttcgata
    19801 cgaaattcca tcgattttcc tcctctgaca tcaataaaaa atgtcaagcg tggaaaagat
    19861 ttttgtatgc cgtatctgct gatttctgaa ggcagatatc ctgaccaatc acgaaaagct
    19921 cttgaaaaac cttcgactgt ttcatatcca tatctaaacg ccgtttctgt cactcttgat
    19981 ccatctagga gatcgcgatt agccaaagcc aatctacggt ttttgatata gtccattagc
    20041 gacatccctg caataaacgt aaagatgcgt tttaattgat attcagagat tcctgtattt
    20101 tcggctatta ttttatagga aagtccttct gtcaaatgtt cttcgatgta atcgatcaat
    20161 tggttcagat ctttaagcat atttatcttc ctccttgctt gcctttttat catattatca
    20221 aagaaagtca attacttgat gaatcaggaa ccaatttagt cagatgtaga aaatgttgta
    20281 tggatctaaa gaaaattctc aagcagcgtt tcgtaacgga taattggtat tatctgccta
    20341 tctatgtttt acctttagaa aaataaattt tggggaagac acattctaag taaacaaagc
    20401 ggtaaaaata tcttttattc ccttagttaa tccgcttact acctactgta caaagcaaat
    20461 tgttgttcaa actgctgatc agaacgctgc ttggattttt ctttgcgata catcatacct
    20521 cttttatcaa ttggaacaat tatttatttc taacaaaatc acttcatttt tgtcagataa
    20581 ataaaaaaca aaaaaagttc catctttaaa acacgctatt cttttacttt ttctcacatt
    20641 ctctaagaaa agaaaaggag aatgaatttt tgacaattcg agcaaaagtg attatcaaat
    20701 atgtaaaatc agctactttt ttcttaaacg tttctttata ctaaatataa ataagtgttt
    20761 catgaaagga gaactagatg aataattggc ttgagtattt tcctgaaaac gttttggaac
    20821 gcggttacag ctatcatctg cacggttttg tccgtcattt gaactataca agcaagtact
    20881 tgtccgcaac agtttctggc acggaagatt ataaggtagt gatcacttgg gatgaaaaga
    20941 ccaacatgac ttgtgattgt ctatatgcca tagaaggaaa aaaatgcaaa cacatggctg
    21001 ctgtcttatt cgcttacgaa gaacgtccaa taaaaaaatc caactactca ctttccgaac
    21061 tctcgtccct tgtttcctcc gctagttcct ctcttgtacg ggagctttta acagagattc
    21121 ttatagaaca tccgcaattt atcgaacgct tcaaagttaa gatgccattt catgcaataa
    21181 attattcaga taaattaaca actatcatcc ataaatacga tcatattatc aagaaaaaca
    21241 aaaacaggaa aacagcgaag ttcatcatgg agatgcgaaa gttcatccaa gaagcagttg
    21301 aatcgctcat tcagcaaaat gcctatcttc ccgcattcga attgatcaat gaagtgattg
    21361 ctactctcga aacattctat tgggagcctg aggatgaacg aacccttctt ctgatagagg
    21421 actgttatta tttatggaaa gaattattag cagaagcacc tcatgcagaa aaaaggcaaa
    21481 tgttctcttg gttcgtctgc caagtcgatc atactgacgc ctcttattca aaacgctact
    21541 ccataaaaat cctgaaagaa gactttcggg aaaaagaatt ttctaaccaa aagaaaaaaa
    21601 tagataaaaa aactaaagaa acggtaaaga aagacgattt caatgaaaaa tagcaagtaa
    21661 acgataacaa ccatcctaaa tccacaagaa atacagcaga ccttgcttta aaaacacgaa
    21721 tcatgcaaag gatgaagtaa agaagactta acgcgtaccc aatattagtc atttgactat
    21781 taggtacgcg ttttgtttta taagtcatga caaatttcct tcgttgctgg gtagattttc
    21841 cggcattgtt gatagatttt atgatacttt tctacatttt gtaagagagg ttccactgca
    21901 tctgtatatt ggataaaatt ctgacaacaa ctttcaggtg tgtcgaacca ctctaatctt
    21961 taaagataaa tattaaaata acgattaata atattaacag tctttatttt tcaccaccaa
    22021 aaacctatct ttgcatatac taaatagacg tatatacaca gataggtttg tcttgtgaaa
    22081 aataatgatt atccttacca aaaaatgttt gtttttctac atgttcgtac ttatcaaaaa
    22141 atatgatcct tattgaaatt actggctatt tatattccaa cgacttcttg tgttaatttt
    22201 tgttatctca tagtaaatta tgtttcattt tcacttaatt tagttgtcac gtgttcgtca
    22261 attcgtaaaa acggtaaata tataaacaca cttgcggcta taattaatat ttgtaaaaca
    22321 gctgctcgcc agtctccggc tgttgctaaa aatcccgata taactggtgg cgtagtccaa
    22381 ggaatttgca ctactacatg attaattaat cccacagcag ttgcaaaata tgctactgtc
    22441 aaagaaaaaa tcggtgcaag cacaaaggga ataatcagac tgatattaaa tacaataggc
    22501 aatccaaaaa taataggttc gcttatattg aatatagcgg gagttaccga taatttagca
    22561 aagtccttat aatcttttct acgactgaag ataaatattg caatcaataa agcaatcgta
    22621 tttcccgatc cacccattac cgcaaaggta tctttaaagg ccatattgat aatatgtgga
    22681 atttgctctt tgtttgcata agctgccata ttttcttgca tattctgaat caaaaacgga
    22741 tctaacaatg aacctgatat tactgcttga tggataccaa atccaaaaaa tagattagca
    22801 atagatgtaa ttaacaaaaa tcctggtaaa ccagttgtaa ttttacttaa tggctctgta
    22861 actatcgtgg taattagctt atttatatcc atattaaaca attgaatgat tataaatgac
    22921 aataaagcaa acgaggtaat cgtaataatg attgggatta atacattaaa agactttaaa
    22981 acagcgggag gaatatttcc ggatagctga atctgtagtt tcttattatt agaaagttta
    23041 ataaataatt ctgtagccgc taatccaaca aatataccta caaacattcc tgaagctcct
    23101 gtataggata taggtatcac acccgtcact tcaacagctt tatccgcatt ttcaggagta
    23161 aacatcatct gcataggtgt taatacaaca aatgtcgaaa tagcaactaa taccgctgca
    23221 atatgatttg tataatttct gcttgcacac atatgataag atactgctgc tacaactaat
    23281 aatgtagtta tgcttaatgt accattggca attgaagtac caatttgttg taacgtggtc
    23341 aatgtactag tatcgacaat ttcccccatg aatcctgttg gttctaagat cactgaatta
    23401 ataagtgtca caaatcctgc taacatcata aatggcataa atgtagcaaa cgcatctcgc
    23461 aaagttctta aatggatctg attccccaac ttagtcgcaa ctataccaaa tttttcaaat
    23521 acaatgtcct tcctgctact tttgcccata ttttttctcc tttatgctta ttgtaatcga
    23581 ttactttttc cacccaaata atacatcact tatcaaaaaa agtaaatact tttaattaaa
    23641 tatatatatc ttttttagta taaaaaaata agctctgaaa aaataatttt cccgagctta
    23701 tttttcaaca aaaacagctt caaaaacaaa gtcttgatat aaatgtctcg ataccgaata
    23761 ctcgaaaggt ttaccagacg atagagcaac aactttgtct atctcaatca taaattcacc
    23821 tggatctatt tttaatattt ttgcgtcaaa ttcattcgca gtatctcctt tgatacgtat
    23881 gtgcgaagtc tttatttcca gacccagttc atttgtgata taagcatata cagatttctt
    23941 taaatgtttt ggttccaagc ctggtatgac tgctaatggc atgaatgttt gctcaatcga
    24001 gtatggttga caatcaataa aacggcttcg tacaatatta tatacatagt cttttacact
    24061 gatacttaat ttatcagcta cttttttcga tggaagttca attgagaaag tatggatttc
    24121 tgaatctacg tgttcttcac caaccacgct aaacaaacct tcgtttggac caagaactcg
    24181 tgagttatca attggtgttc tgacgacttc agtcccatac ccacttctac ttcgcaaaac
    24241 tccttcggaa acaagtaagt ctacgccttt ctttactgtt aacttgcttg tatgataaat
    24301 aactgccaat tcatctcctg taggaagttt ctcaccaatt ttatactctc catttacaat
    24361 ttttttcttt atatctaagt aaatttccat atacttcgca atttttttca atggtgaccc
    24421 tccaatcaaa aacatatctt catctatact ttaacataaa taaaccgata aaatccacat
    24481 caaaattata cacacaataa aaaagatata tatatttaaa caaaactatt tactttaagt
    24541 tgtaagcggt gttatcatta agtggaaaca ggaggtaaaa aaattatgac aactatgaaa
    24601 aagctaactt ttccagatga tttttggtgg ggttccgctt ggtcagctga gcaagcagaa
    24661 ggaaaaggag aaacaggaaa agcagagact atctgggatc gctggtttaa agaacaacct
    24721 taccggtttt atcaacgaat cgattcctct attacaaccg atcacatcca tcaatataaa
    24781 gaagatatag aactaatgaa aaaaactggg cataactcct ttcgcgtttc tatttcttgg
    24841 gcacgaatgt ttccaaatgg cggtaccgga aaagtaaatc ccaaagccat ttctttctat
    24901 cgaaaattat tttccgaaat gaataataac ggaatcaaag tatttgccaa cttatatcat
    24961 tttgacatgc ctgctactct tcaagataaa ggaggatggg aatcacgtga agtagttgat
    25021 gcttatgttc attacgctga aacttgtttt aaagaatttg gtgacttagt ttgtcattgg
    25081 tttaccttca atgaaccact tgggcctatt ttaggtactt atcttgaaga ttttcattat
    25141 ccaaacctca ttgactttaa acgcggagcg caagcagcat tcttcactat acttgcacac
    25201 gcaaaagcaa tacaagtatt taaagaacta gctcttccta gtaaaatagg cgttattcta
    25261 aatttgagtc ctacttttcc tcgtagtcaa aatcctgctg atgtgaaagc agcagaaatc
    25321 gctgatttat tttatacgcg gagcttttta gatcctatgg ttaaagggaa tttttctaaa
    25381 aagcttatcc tgttattaca agaatataat cagcttcctg aagattatac gaaagaagat
    25441 cttgtatgta tctacgaaaa taccgctcaa attcttggac taaactatta cgagccacgt
    25501 cgcgtcaaat ctcgttcttc tatggtggat acatctagtc catttttacc agagtggttt
    25561 ttcgaaccac atatcatgcc tggacgacga atgaacgaat accggggatg ggaaatttac
    25621 gaaaaaggaa tttatgattt gtgcatggat atcaagaacc attatggaaa catcgaagca
    25681 tttatctcgg agaacggaat gggcgttgcg gatgaagaac gtttcatgga tgatacaggg
    25741 caaataattg atgattatcg gattgagtat atcaaagatc atcttgctta cttatggaag
    25801 gcaataaatg aaggatgtaa cattaagggg tatcatcttt ggacatttat tgattgctgg
    25861 tcatggatca acgcctataa aaaccgatat gggctggttt cactcgacct tactactcaa
    25921 aaaagaacaa ttaaaaaaag tggcgaattt tacaagcaat taagtgatac aaatggattt
    25981 agatacgatg tagacttgtt agttgaataa tattctaaaa ttccacttga agtgaacaca
    26041 ttagaaaaca agaataatga gaaataccaa taacaaatac tttttcttca tacttcattt
    26101 atacttgtca gtataagaga ctgtgacaaa tgtagtgatc ctcagaagtt aggtctggaa
    26161 atctaacttg agaagatttt tttaaactac gtccagtctt ttttatttgt ttaaaattga
    26221 agttgacaag tcttcattaa aaatttagaa tattcacaag tttgacgaca attatgaaaa
    26281 tttatgtcgt gctaaaggag ttttgttatt ggatgaaaag ttagatataa aaactgcgat
    26341 caaagacacg ttacctaccg tttttggtta tatcggtatt ggacttgcat ttggtatcgt
    26401 tgggaaagct gccgggtttc atccgctggt cgtcacgttg atgtccctgc tgatctatgc
    26461 tggttctgcc caatttatca cggtcagcat gcttgctagc catagtccac tgctctccat
    26521 cgttctctcg acctttctag tcaattcccg aatgattctg atgagtatga cgattgctcc
    26581 ttatttcaag aaaaatcggc tgcttcaaaa tctgctgatt ggcacattgc tgacagatga
    26641 aagtttcgca ctgggaatga ataaattgaa ctatactgga caaaagttaa actttcgttg
    26701 gatgaataca gctaattgga tttcttattt gacgtgggtg ggttcttctc ttgttggcgc
    26761 acttttaggg aattttatta ctgatccgaa aaagtttggt ttggatttcg ccatcgtcgc
    26821 tatgtttatc gggttacttt atcttcaagt catttctgat agaaacacct ctaaacgatt
    26881 acagttgatc ctgattggtc tcactttgat tctggtatat gtcggactga tttttatccc
    26941 aagtaactta gtgattttag ttgtaacact gattgggtgc ggattggggg tgtggatcaa
    27001 acatgccttc ttttgagttt acattgctga ctattttagg ttgtacttta gcaacttggc
    27061 tttctaggat cctaccattt gtcttactga aaaaattcga tttgccgcaa ccgttgcttg
    27121 agtatttaag ttttgtcccg atcgtcatta tgtctgcttt atggttcagc agtctattta
    27181 cccaaaatat cggacatctg ccgcagatca atctcgaaaa tgctttggct tcagttccta
    27241 cacttttagc tgctattctt tcaaaaagct tattggtgat cgtcttggta ggaattcttt
    27301 ccctttcgtt gattcgctta ttataaataa aaaaacaaga gcttatggca aattactgtc
    27361 atgcgctctt gtttttatca aagtcaaata agaaaaaaat cggcgtattc ttgcttatcc
    27421 gttgaacgga ccactaacaa cgacttttcc taatatatgt cctgtttcta cgtctttggt
    27481 tgcttgtttc aagttcttcg cattcatccc atctgaatag accttgctca atgtactgcg
    27541 gataatccct tcatttgcta aagcagcaat gtgcgctaaa gcttctcctt gcgtttcgat
    27601 ttcatagtta tagtctgttt tagcgaacat atactcccag tcgaagctga tagattggtt
    27661 tttccaaaca cctatatcta acggctcttt gatccctacg atcgttccca catgtccaaa
    27721 tggtcggaca aggtgtttga tttgatcaaa gtagcgggta atatcgaata atacagcgac
    27781 atactctact tgatcgattc ctaattcacg aaaactttta cttaagtcgt gatgataatc
    27841 gattggatag tctacacctg tttttttcag ccattcaaaa ttcttcggac ttgcagtcgc
    27901 gtagacttct aggccagccc aatgcgctag ttgattcaaa atcgaaccga cgcccccagc
    27961 tccgttgatc actaagattt ttttcccgcg gttggcattt tcttctggag tcagaccaaa
    28021 tttttcaaat aacaattcat aagcggtcaa tgaggtcaac ggcaaggctg cggcttcttc
    28081 atctgaaaga ttttttggtg caagagcgac aatacgttcg tcaaccagtt ggtattcttg
    28141 attgcttcct gctcttgtcg ttgtacctgc gtaaaaaacg cgatcgccga cagaaaattt
    28201 ttgcacttca tcacctacag caacaacttt cccgactcca tcaaacccta agatacgtaa
    28261 agcatttctt atcccgttat cttggcgaag tttcgtatcg acaggattaa cagatactgc
    28321 gttgactttt accagaagat cccgtgaact gggtacaggt atctgttctt tttcatcaat
    28381 aaagcttttt ggatcatcga tcgacaaccc ttcataaaaa ccgactacct tcattaattc
    28441 cttttctgac atacgaattc ctccttagct tcatcaagtt ggagcatcca tacagttttc
    28501 atttcaatat atatagtatg ctatttgttc cacttttatt catcataatt attctcttac
    28561 ttaaagtaaa ctatttgcac ttttttggtt aaaaaagagg ttgcgacaag acttttgtca
    28621 caacctcttt taaacggtgt tcaatcaact gaccctcggt attcgctcaa aaaacgacaa
    28681 aatatgagga gctatttttg tttggctgtt cttattactt gatgcaggac agctttttca
    28741 cgacctctaa ttcacggtgt tcaagcaaga aatcattgtt cactgaaaag cgttggatgt
    28801 tctttttcaa aggtgtctaa gatctctcgt acttcatcag tagatttcgt attcatcaac
    28861 tgaactcgca agtcatttgc tcctggaaat cctttgatat agattttaaa gaaacgatgt
    28921 agtcctgtga tggaacgcgg gatgatttct gaataatgat cttgcagatc tagttgcaga
    28981 cgaagtagtc cgatcagttc tttttctgta tgttccctcg gttctttttc aaatgcataa
    29041 ggattcttga aaatcccccg gccaatcatg atgccatcta cgccatattt ttcggccaat
    29101 tcttctcctg tctggcgatc tgggatatct ccgttgatcg tgatcagtgt ttgcggagcg
    29161 atttggtcac gtaaagcaat gattttaggg atgacttccc aatgtgcatc tactttactc
    29221 atctctttac gcgtacgcaa atggacagaa agattggcta tatcttgatg aagtaggtga
    29281 ctgatccatt cttccatctc agacatttcc gtatagccga tacgcgtctt gacgctgaca
    29341 ggcaaaccgc cagctttagc cgcttcaatc aattgtgccg ctacttctgg gcgaaggatc
    29401 aagccactgc cttttccacg ttctgctaca ttagggactg ggcagcccat gttgatatcg
    29461 attccttgga agcccatttc tgccatagca atgctcattt ctctaaaaaa ttctggcttg
    29521 tctccccaaa tatgggcaac catcggctgt tcatcttctg taaaggtcaa tcttcctcgt
    29581 acactgtctt ttccatctgg atgacagaaa ctgtctgagt ttgtaaactc agtaaagaag
    29641 acatccggtg ctgctgcatg ctttacgaca tggcgaaata caacatctgt tacatcttcc
    29701 attggtgcta aaacaaaaaa aggctttggc agctctttcc aaaaattagt agtcatttat
    29761 ttgttactct ccattctatc aagcagtgaa gtcgcaatct ttctcaaaaa cattgtcatt
    29821 atactaggaa acaaaaaaag aagcaaagtg aacagcttaa aagatgtttc tgattgagca
    29881 aaaaaagact gtgacaaaaa tcttatcaca attccttttc cggaataaat ggtgttcaaa
    29941 agcttgcatc tgcggtaata agtccaacca aacgaaaaat aggaggagct atttttgttt
    30001 ggctgttctt attacttgat gcagaacagc tttttcacaa cctctccact aaacggtgtt
    30061 caatcagctg accctcggta ttagctcaac aaacgacaaa atatgaggaa ctattttccc
    30121 gtttgtttct ctaatactca ggtcaaaacg ctgatttcac aacctctttt ctaacttctc
    30181 aatcctcttc ctttattgat caaataccaa gtaacggcgt acaaaacaac gatgaatagc
    30241 acaagtacga tcatcgatgt tgctactggc acatcgattg ttccaaggaa tccgtaacgg
    30301 aaaccggaga tcatataaac gatcggattg actttcgaaa cagcttgcca aaatggcggc
    30361 aacatagaga tggcatagaa aacgccacct agataagtta acggctgcaa gacaaatgta
    30421 ggcacgatcg atacatcgtc ataagactga gcaaaaatcc cgttgagcag tcctgctaac
    30481 gaaaacaaga ttgccgtcat caataatgta atgatgacca tgaaccatga atacacatga
    30541 agtggtacaa agaacaagga aatgatcgtt acgagagagc cgacgagaat actgcgaccc
    30601 actccgccaa tcacaaagcc ccaaatgatc acatgcgtag gaacaggcgc taccaagatt
    30661 tcttcgatgt ttttctggaa tttttgagag aagaaggacg aagaaacgtt ggcatacgaa
    30721 ctagtgatag cagacatcat aatcaaacca ggcacgatga attccatata tgaaaaacca
    30781 cccatgtcac cgatccgacc accgatcatt tttccgaaaa taacaaagta caaggatgtc
    30841 gtgatcacag gcggaaccag tgtttggacc cagatacgca aatagcggtt cgtttccttg
    30901 atagctaaac tttttaatgc agtaaaataa agattaaaca tttttctcct ccgtatgatt
    30961 attttcttct gtgattttca aaaacagttc ttctaaacga ttcgacttat tcctcataga
    31021 aagaactttg attccttgtc ttgtcagctg atcgaagatt ccgttcaccc cttgatttcg
    31081 ttcaacttcg acagcgattg tctgttcatc ttcaaatgta caagcgtatc cttcaatcac
    31141 aggtttggtc tcatatggcg ctaaatcaaa gataaatgtt tcaaattgca gtttggatag
    31201 aagctctttc atactagtat tctcgatcag ttcacctgat tggatgatcc cgatgttgcg
    31261 acaaagcatt tcagcttctt ctaaataatg cgtcgtcaaa atgatcgttg taccattttc
    31321 gttcaattct cggagaaact cccacatctc gcgtctcaat tcaatatcga ctcctgctgt
    31381 tggttcatcc aagatcagca aacgtggttc atgcatcaat gccctagcaa tcatcagtct
    31441 tcgcttcatt cccccggaaa gcatacgtgc acggacattt ctcttttccc aaagattgga
    31501 ctgcttcaaa tatttttcgc tgcgtttcat cgcttctttg cgagagacac cgtagtagcc
    31561 tgcttgattc acgacgattt gctggaccgt ttcaaaggga ttgaaattga actcttgcgg
    31621 gactaatcca atctgttgct ttgctcggac tagatccgta tccagatcat aaccgaagac
    31681 attcactttt ccagatgttt tattgactaa agaagtaatg attccgatcg ttgtagactt
    31741 cccagctcca tttggtccta atagcgcata gaaatctcct tctttcacgg aaagatcgat
    31801 tcctcgcaat gcttcgaccc cacttccata aacctttttc aaattattta tttcaagcgc
    31861 atttgccatt tatttcctat ctccttatag acatgattct ttattgtatc atggaataca
    31921 gcagatgaaa aaacaacttg gttccagcga aaaatcaggt tgctgggctc aggaaaatct
    31981 cctaatgaaa gacatcaatc ggacgaagtc agacaacctt ttcagaaaaa acaaatcgaa
    32041 gataaaggat tactattcat atgtgcaaca aaaggagcgt gagacaaaag taaagaacac
    32101 ttttgtctca cgctctaaac acgtataaac ggcggaagca aaagccaaga tttttgatcc
    32161 aataaatact ttcgatcact tcgcctatcc caatacatgc cactgccgct tttcatcaaa
    32221 taacgcggct tccgtttttg cggtttctac taaagtctct gggtaatcca aaactttcag
    32281 caaggcaatc gcatttcggg tccttgaagg tccttctttt aatttgaaat caaaactgat
    32341 tccttttcct tctgttactt gttcttcaaa gtggacattc tcacaataat tctttaaaat
    32401 ctctgtcaat tcgatatcat gtgtggcgac aaatgctaaa gatggatact ccgcaagcca
    32461 ccgaacgact gaagcggaag aagcaatccg ttcgatcgta tttgtccctt ttaaaatctc
    32521 atctacgaag cagtagcagc gttctttgga agccacttgg tccaacaaac gtttgatcga
    32581 tttgatttct gaaacaaaat aactgtcgcc ttcaaataaa tcatcttcga ttgccatgga
    32641 agtcaacaca tgtccaggtt gcagggtaaa ctgttctgca atcgctgttt ggatcgtctg
    32701 tgctagaata cagctgatgg ctatactttt gacatacgta gattttcctg atgcattgga
    32761 acccgtgact aatgtattct tctgccagtt gaccggattc actaccgctt cttttaacaa
    32821 tggatgatag atatctttcg ctgtcacacc gccctcagta aactctggtc ggcaagtgat
    32881 gggcatataa gtacggtaat tcaatattgc agcggctact tctaattctc ccagcaattc
    32941 ccacagcttg atggcttcag ttgaatgctt ttctaattta gtgagaacga aatgatagga
    33001 gataaatggc agcatgaaca tgatgttgac atattcaaaa atcaactctg cttcactccc
    33061 actcttcata cgaaatgaaa aacctaattt agggatgtct cttaatggtt tagtttgctg
    33121 tttcagctct tcttgaagtg gtgtcggcag ttttgctagc tgattggcgg ctgaaatcgt
    33181 tgaaaccaaa taactcatgc tattcagctc tgtttctagt gtttgtttct tcactagata
    33241 atagaccgta ttgaatacta acccaccgat tgccaaatag attcctagta cttgtcctaa
    33301 aagaagcaaa cccaaaccca ccagcggaag caagccaaga aaaataaata aacctacgcg
    33361 tccaatcttt ttactttttc catccgctag atattgtttt gcaaaattat gatctttttt
    33421 tcctaaacga gcgaattgat attggatttt ttctctcagt tgaggatttt cctgataaaa
    33481 agcaatcagt ttttctaact gctgatcttc accaaaatca aagctgcgta aacgttgata
    33541 caacgcttct gaacctacac tagaataggt actgttgatt ccttcgaata cttcgaacat
    33601 atccaggtca taccaagtaa gatcatcgat ttcgctatcc catgaacgga acttcttctc
    33661 cgtgagccat gcttccttca agctttcttc tttatcaaat ctcggttgat aaggaatttt
    33721 ttcccatttg ctacgaactg tttcctttaa tttcaaacgt gaaaaaatgt ctaaagcaac
    33781 taataaaata acagctgcaa taataattaa aacgataaat tctctttgac ccatatccct
    33841 ctccgttcct ttatttgtta gctttagtat agcactgttg cgctatttga aaagagggta
    33901 aaaaaacacc tttcaaaata aaaggtgttt ttttcttgta tattacatat ttatctctca
    33961 tttatcaaaa ttgacaaata atcataggga ggaattgttg ttaattcttg tttattctcc
    34021 agtgcattga caactgtccc aagggaaagg atagcctcag gtactatttt ttcttgttct
    34081 gttggattag ctaagcgaag aacaaatcct tgttcatgaa aataagaagg ataaatcgat
    34141 gatacaatta agtcttcagg taattcaatc aatgaaaatt tacgaggaac atcaagttca
    34201 ttttgtaatg gccaaatctt gttatctaac ctgtgaataa atacattcag tttctgcttt
    34261 tgataagaaa tagattgttc taaccgtttt tctgcctgtt ttgccacttt gaactcatta
    34321 aatcttcctt cttctacatt aaatccaaaa gtgactttat actcacctat ctcttgagct
    34381 agcggtgttt ccatcatgac atgcccttca tttgtcgtat ctcctgaagc tcgcccaggt
    34441 cgccaagcaa gattaggttt tccaagttcc cctgttgttg aaaataaggt tatgattaat
    34501 tgattttcta tacgttcata ctcttttaaa ccatctgcat aaaacgtaaa ataatgatca
    34561 ttttctgcca cagagacact cttatcgaat atttctaaat taacaggttt ctctaccata
    34621 gtttctgacc aattcggagg aatgacatca ggggtatttt caataaatcc gttttgaatt
    34681 tgtgcaattg atttttcaga tttatctaaa acattaattg ctaagcgcat acgatgcgag
    34741 taaacagtat tatgaatttt gagtgtgcct tcaacgattt gactttctcc cagactgaac
    34801 gatatttcat aagatatttc ttccatttcg ggtttttcag ataaacgatc ttttaaatct
    34861 ttaggaagtt gagcttttcc gtaaacaact aatgtttctt gtaaagaatc tttatatact
    34921 ttagctgttt ctaattttag agatagttct gtatctcctt ctaatggtga ataatcatac
    34981 gtatcgccat catttgctga atcgatcaaa tgaacgaaat caagatattg tctatctcca
    35041 actatcaaat tcaattgccc atctttaaaa gaaagtttat atttattgtt acttatctca
    35101 gttttgtcta tctcgattgc tgtttctaat ttttcattat ttttctcaaa ttcaacaaca
    35161 gtgtatccta gtgctggcac atttacattt atttttatgt caagttcata ataagctggt
    35221 tcatcaaaat attcgaaacc tgtagcaatc atccgataag catttttccg ttctggaaaa
    35281 taaacttctt tttcaatgat attataggga ctacctttga agtgtatttt ctttgaatca
    35341 gctactacat gcacgatttt cgatccacta taattctcag tcgttgtgtt gaaaacaagg
    35401 acttcattcg attttagctt taatgcatca gccatccgtt ttacaataag gttttcgatt
    35461 ccgtcagcta tctcattagc ttctttgatt cgatggaaaa tatcttccgc aacattatct
    35521 gaaacacagc caccaatact atcatgagcc tggttttgca aaatcttttt ccataaccga
    35581 cgaagtaggc ctttactgat atggatacca tttctttctg caatcagcat gagcggctca
    35641 actcgtttta gaattttttg ttccaattta aaattttcta ttttcatttt tgttcttact
    35701 gagccaatag aacgatgaac acgagagtaa accggctgac gaagttcacc tttatattca
    35761 ggtaattctt ttttgtttct gataacttct acataagaag gataatctga aataatattg
    35821 tggaatttac tgtatttatt caacttctct acgacttgat caaaatttaa aatcattgac
    35881 ttttgatcta cacccgaagg tactaaaata tctttgtttt ttccttgcat atgaagcatt
    35941 tcaactgctt catccaactt ttcttttgca aattcaggaa tatctttaat tgcgtctaag
    36001 gtcatcattc cagtcatata accaaatgga aaattcatgg cataaacaaa tttatctccc
    36061 aatcctttcc agataaaata aggagatgga accatcgttt caaagtttaa tcctcgccaa
    36121 cacatgaaat tatcgatttc tacttgatgc aaaagtgtag gcaaattcgc attgaaccca
    36181 aacgtgtcag gcaaataccc taccatcatt ggatctccat atttaaggat cgtatcactg
    36241 attccaatca ttaagtttct taaaattgat tcagcatcca ctaataaggc atctgtttgt
    36301 gcataccacg gtcccacgaa tagttgtcct gttttcatca gtcgttggat aaccttaagc
    36361 ttttgcggat tgatctccaa atactcatcg acgattgaag tttgtccatc taaacaaaag
    36421 tttactttag ggttcctttc caattcatct agaacttcag taaagacctg atcagacaat
    36481 acgatggcat cttcatttgt aaaataccat tctctgtccc agtgcgtgtg ttgaattata
    36541 tgtgcattta ccatatcaga ttctcctact ttccttcttc tactgaattt acttgttgtt
    36601 cttttttata cttgatggat tttagtgcat tgaccattaa cgctgtaacc actcccccaa
    36661 taacaattga tactaaatat aaaggtatat tcgtaacaaa aggaattgcc ataaaggttg
    36721 aaagcattgt ttcttgagta acaccaaaaa atccatttag accacatgct actgcagtgc
    36781 ccaccacgat gcttggtatt actcgtaaag gatctttcac ggcaaacggg atcgtccctt
    36841 cagtaatccc cacaaggccc ataatcatag ctgtctttgc attatctcgt tccgattcat
    36901 cataaagttt tttgtttaaa attgttgcta aaaacattcc aaatggcgga atagcaattc
    36961 ctaataacat ggctgtacta ggtccaaagc ttccgcttga aaaagaagca accccaaaag
    37021 catatgcgat tttattgata ggtcctccca tatcaaacgc catcattcct cctaaaatag
    37081 ccgacatcaa agcagcattt gctcctgaca tgccttctag ccaattagtc agtcctgttg
    37141 tcattgcttg aataggcgta gctagtacat accataatat gattccaaca actaatgtag
    37201 taacaaaagg aatcagcata attgatttta gactaataac ttgcatcggt acttttactt
    37261 ttttcaatgc attagctaaa tagccacaag ctaatccagc aaccattcct ccaataaatc
    37321 ccataccaag attttgacac atcatcccag tgataaaagc tggtgctaga ccgggacggt
    37381 cagcaattga atatgcgata taggctgaaa tcatcggtac gataaactgt aatcccgtct
    37441 gaccaatcat tcgcaggact ccccagaatg tatccgtctg gtcccaaaca cctgtgccac
    37501 caaaaatgac tgcaatagaa gttagtaacc ctgctgctac gacaagcggg atcatatagg
    37561 aaaccccact ttggaaatga tttagaattt ctcttccttg tttcttgaat tccattagta
    37621 actcccccac gatatatttt ttatttgtta attaatgcaa ttgcttcatc aatcgtctct
    37681 tcaccatctt ttactacctc tgaggtccct actgttaaaa tcggtttacc gtcaaagcga
    37741 cctcgttctg aaacatttgt atctactgca aatatgacaa catctgcctc ggaaacatcc
    37801 gaaattgaaa gtttgttttc tatccccata gccccctgtg tttctacttt aatatctaac
    37861 cctttcttct tcgcaaactt ttctaaatta gcttttgcca tataagtatg ggcaatccct
    37921 gcgatacatg ctgttactgc tactattttt gtcatatgaa attcctcctt ttaaaatgat
    37981 agagctttta ccaattcttt tttatttctc gaatctttta ttcttttaac aaactcgtca
    38041 tccatcaatc ttccagataa ttctgctaaa atacgtaaat gattagtacc tttatcagtg
    38101 tcttttattg ctaacaaaaa gacgagatca actggttgat catctaatgc gccccattca
    38161 acagaccgct ttaacttggc tacagccact gttgattcaa ttactgctag gcttttgcca
    38221 tgaggaatgg cgatattttt cccaattcct gtggtcatat ggttttctct gtcaaatacg
    38281 tctttttgaa attgtttgtg gtcagacaca aacccattag tctctaacaa tttcgataat
    38341 ttttcgacta cacttttttt atcagatgca tttaaatcta tcactatatt atttatattg
    38401 attttttcac tgatcattta taagccttct ttcaatatat aaactaattt ttcaaacgac
    38461 gaactcgttt ttaaatttgc taataactca tgattcgaag cgatttcatt gaatgtttca
    38521 taaattttat tcaattcagg ttttactttt tcattaagtg caaaaaagaa aacagaatga
    38581 acaagtgtcc catcccaatc aattccttct ggattaacgt agacacagat tactggcttt
    38641 tttataaaat ctacttcgat atgcggcata gcaaaatcat tcatcgctgt tgaagatagt
    38701 ttttctcttt tgattgctcc ctctagtatc ccttctttcg cgtaattttc ttttaccaat
    38761 tttttggtaa ttatatttaa aacgttcact tgattatcct ttatttggtg ggtaaaaaag
    38821 caaaatcgtt tatctaataa atttagaaaa gcatcttctg tttgttcatt taactgtaga
    38881 tactgtttta cttttctgac atctgcccct aacatcaaag gactaacaac aataacagga
    38941 aaatttgtat tttcaatcgg aatcgtgctt ataacaagtt catcagtgac ttttctatct
    39001 tgtagttcat tgatgcttag tacatcttct atctcaacca tatctgcaaa accgttattt
    39061 attctttgct ctaataattt tgatgttcca tatccgctac tacaaactaa tatcactttc
    39121 gttttgtcag gtttgtaacg atccaaaagt gattgaatat ggagtgttac gtaagcgatt
    39181 tcatcttcat taaaatgtat acagaatctc tcttcgattt cctctaataa atctacactt
    39241 atcataaatg accttttaaa agaatatttg attttgtccg tataagggtt atagatattt
    39301 actcccaatt tgagtctttt aactgctgca ttgagatgta atactagatt attgatcaat
    39361 tcttcatcag gataaaattc atttaattta attcttacta actcttgtag ctcaacaccc
    39421 atatctaaat aggaaagctt cgtttgatct aagtcgtgat tcatagcatt tttttcaatc
    39481 gaagtaatgt gaatgtcaac ataagcttgt tcatctattg gcacaataat tgaaaatgct
    39541 ttttcaatca ttttgattaa aataagtgta ttctttgaga tttcttcttc agaattatta
    39601 ctacgtgata agaaattgct tgtttcaatc ctttctatcg caatagcaag gtggatagct
    39661 aaagtttgaa attcataatc tgtaaatttc aattgtgtct tattcatgta tcgattaagc
    39721 aattcggcta cttttttcaa tatgtcctta tttaagaaat tattcgcttc accaatgaaa
    39781 ttgatattca agtctaagag atctgtttta ctgttagatg ctgtaaagcc accccaataa
    39841 tagttcacaa cttctgacat caaccttctt ttactttttt catcagcttt gatgcgcacg
    39901 ccatttcgat ctgaaactaa ggacatccca tgcttgttta gtctttttct aacatctttc
    39961 attgtgcttt ctaccgtcga cctgctcacg tataattcgt cagcaagatt ttgaatcttt
    40021 agagaatcat tagtattcaa taatttagca aacacataag ttagacggtc ctccggagag
    40081 tctgcgatat tgattttatg actggataat aaatttcgaa gtgtttcttt ttttccaata
    40141 agcgaaacgc cttttttagg ttgaaccaac atttgtacat ctggcatttt ttggattatt
    40201 tctttcaaaa ttaaaatatc tttgctaatt gttttcgtag atacatataa ttgttctgat
    40261 aattctttgt aagttgtgtg ctcattttca atcaaaaagt atagtatttt catttgccgt
    40321 tcgctaaatt cgatgcccat tatcttcacc tcctgaatac agcttaagtg tacaattatt
    40381 atctctattt tcatacagaa gaaagttctt gattaatgta gaagtttcta atattcttga
    40441 ttatttcaaa tcaataaaaa agcctgcaat at
//
LOCUS       DAPBAF010000026        39973 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.026, whole genome shotgun sequence.
ACCESSION   DAPBAF010000026 DAPBAF010000000
VERSION     DAPBAF010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 39973)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39973)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39973
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.026"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(104..1336)
                     /locus_tag="RD451_001543"
     CDS             complement(104..1336)
                     /locus_tag="RD451_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HDT7566810.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            1591..2160
                     /locus_tag="RD451_001544"
     CDS             1591..2160
                     /locus_tag="RD451_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDT7566811.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(2338..2778)
                     /locus_tag="RD451_001545"
     CDS             complement(2338..2778)
                     /locus_tag="RD451_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HDT7566812.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            2936..3700
                     /gene="map"
                     /locus_tag="RD451_001546"
     CDS             2936..3700
                     /gene="map"
                     /locus_tag="RD451_001546"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HDT7566813.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            3732..4655
                     /locus_tag="RD451_001547"
     CDS             3732..4655
                     /locus_tag="RD451_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HDT7566814.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            4731..5870
                     /locus_tag="RD451_001548"
     CDS             4731..5870
                     /locus_tag="RD451_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HDT7566815.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            5863..6663
                     /locus_tag="RD451_001549"
     CDS             5863..6663
                     /locus_tag="RD451_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDT7566816.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            6663..7490
                     /locus_tag="RD451_001550"
     CDS             6663..7490
                     /locus_tag="RD451_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDT7566817.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            7468..8202
                     /locus_tag="RD451_001551"
     CDS             7468..8202
                     /locus_tag="RD451_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDT7566818.1"
                     /translation="MLRIGRCEFVRSVCIATFNGGRYLREQLDSILSQLSAEDEVVIS
                     DDGSVDDTWDILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWL
                     ETKVKKITDYFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYI
                     GAGMAFRSSLKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIET
                     HSKLRQKISWRVHLITALIKRKWFKR"
     gene            8302..9168
                     /gene="rfbA"
                     /locus_tag="RD451_001552"
     CDS             8302..9168
                     /gene="rfbA"
                     /locus_tag="RD451_001552"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HDT7566819.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            9182..9754
                     /gene="rfbC"
                     /locus_tag="RD451_001553"
     CDS             9182..9754
                     /gene="rfbC"
                     /locus_tag="RD451_001553"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HDT7566820.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            9776..10804
                     /gene="rfbB"
                     /locus_tag="RD451_001554"
     CDS             9776..10804
                     /gene="rfbB"
                     /locus_tag="RD451_001554"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HDT7566821.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTNILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWKPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            10902..11753
                     /gene="rfbD"
                     /locus_tag="RD451_001555"
     CDS             10902..11753
                     /gene="rfbD"
                     /locus_tag="RD451_001555"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HDT7566822.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLQYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEELGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            11787..13820
                     /locus_tag="RD451_001556"
     CDS             11787..13820
                     /locus_tag="RD451_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566823.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFPLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMTAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFAALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            13864..15143
                     /locus_tag="RD451_001557"
                     /pseudo
     CDS             13864..15143
                     /locus_tag="RD451_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
     gene            15353..16159
                     /locus_tag="RD451_001558"
     CDS             15353..16159
                     /locus_tag="RD451_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7566824.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            16171..17391
                     /locus_tag="RD451_001559"
     CDS             16171..17391
                     /locus_tag="RD451_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7566825.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGEVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            17381..18967
                     /locus_tag="RD451_001560"
     CDS             17381..18967
                     /locus_tag="RD451_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HDT7566826.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLFINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAEPQNSNYVKVLEVTQQTKQDETIQQIPFNNFTGENETLSFPVSETT
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKELPEFVLTDISG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHHLLEENTRLD
                     HTLKTTTNRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSICIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVSREEVNQAEQLAKGTEAGFELRILCEQ
                     ERSFLVEAVAQNGQSWIIEM"
     gene            19006..21144
                     /locus_tag="RD451_001561"
     CDS             19006..21144
                     /locus_tag="RD451_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDT7566827.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEAQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRKENGHISLATNSALEIAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDVIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPADHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVRPGRISGFYEIAYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYSNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTVMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     TLEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPAYIAHDPFYNDNLTKEGIGDFSLRPD"
     gene            complement(21512..22495)
                     /locus_tag="RD451_001562"
     CDS             complement(21512..22495)
                     /locus_tag="RD451_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HDT7566828.1"
                     /translation="MNKQELHDFIGFRQPNICQIVAYKDGVEVYTDEWNGYKKDDTCH
                     IMSATKSIVSLLIGIALEQGLIKSIDDKVLDYFPEYKVKRGEKTIYAITIKHLLTMKA
                     PYKCKGDPWTKVCSSEDWTKTSLDLLGGRKGITGEFNYQTVCLHILTGLLYQTSKLTT
                     VDFANKYLFDPIGIPNHVNYYAETAEEHKQFTMDKSPKTNVWFCDPLNIGTAGYGLCL
                     SASDLAKIGVLCLNKGMYKGKQIVPPMWINEMFKPRTSALEDLQNMRYGYLWWVLDSE
                     NEIYSAIGNSGNVLYIDAKNNLVISITSYFKPMIIDRVAFVEEYLKPFILK"
     gene            22873..24264
                     /locus_tag="RD451_001563"
     CDS             22873..24264
                     /locus_tag="RD451_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HDT7566829.1"
                     /translation="MNKNGEWSAARRIFIILMDVIVYNAAIYSSFLLKFRGEIPLRNL
                     ETFQHSAIIISVIFIALNILLGAYVFYNRMISDIVFVTVIGQVLMTLGIMVVTFAGRW
                     FAFPRLVILLSFVLGTLFLSIYRILVYKLYLRVSRDKKVVIIGLEKDVAPAIQNFGSK
                     KNNKHKVEAVILDNYYANIKNMIKDIDIVYLASHIEETEKIKIYQLVTKNEKKLFLNT
                     TFENLTLINPNIMNFEDESIIETSGFRIQPEYELFKRLFDIIVSLVLLVIASPFMLFT
                     AILVKVTSPGPIIYKQVRITKNQKEFSIYKFRSMTATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNAENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLMLDLKILLQTIKILFDKMSSQGLEEDENVIS
                     LAEIAFPNEKIFR"
     gene            24280..25320
                     /locus_tag="RD451_001564"
     CDS             24280..25320
                     /locus_tag="RD451_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDT7566830.1"
                     /translation="MNNPKFSIIVPVYNAEATIGRTIDILKELDYEEYEVVLVNDGST
                     DQTQEIIQELIENDERFELITTTNQGPGLARNEGIRQSKGEYLLFFDADDTPVKTILS
                     DYDHLLEKSPKADLVVSSFVFRTMDEGRIVSEKENLVTECHYLTHEEFIKDMYQLMNE
                     QLMYVVWNKCYRSDILKNNQILFKTYNSCEDRIFNLHYYEYCHQVIMNPKVEYIYEFE
                     GGKGITNQYRPNKFETFKEFYSLANTVTDDINKDGMAALLLKGTTSVIFSIYSTSART
                     SKEKKDEAKQILSDPVIREAKQIAKTDSSAKKITKLLYNMPAPLFLSAVKVGSFVEVK
                     MPGLMAALKRVY"
     gene            25339..26424
                     /locus_tag="RD451_001565"
     CDS             25339..26424
                     /locus_tag="RD451_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HDT7566831.1"
                     /translation="MKRILHFQGRMGLGGAESFMMNLYRKIDRTNYQFDFLIYEDYAD
                     VQDYHSEIERLGGRIFVVPNPKKNIFKYLIEVNKLLKKESFSIVHNQVYFGGGINLWL
                     AKKNGIRQRIAHSHATEDGKSQNIVMNVLRKFLTKLLLQNATDYLAVSQEAGESLFQN
                     HPFEIVHNGIDLELYSKNSEAKVNKRKELDISMSTFVVGNIGRLEKQKNQSYLLEIFL
                     EILKMNSDSYLILVGEGSLRNKLKAKAVELDIEKRVKFLGERNDIPELLSVMDVFVMP
                     SLYEGLPMVGLEAQAAKLKLVLADTISKDTKLTNNVDFVSLDETPQEWAKKVIKEPYA
                     NKITQELKSYDVSYTTEQMESIYSRDH"
     gene            26457..27419
                     /locus_tag="RD451_001566"
     CDS             26457..27419
                     /locus_tag="RD451_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HDT7566832.1"
                     /translation="MKICYLILAYNDIGNLKRLVNRLNENAVFIIHIDKKTDIEPFIE
                     AFKSYDNVEFLCNKNRVKIYWGGFSIVQAEINLVKRALQNEKYLKYVLLSGADYPIKD
                     NEYIYNYFKKNSSVEFIRGIDLDQIKHKEFYYKHIDVYQKHDYPRINRNNTTAFKIFR
                     AIINRCLRMIKLPPKIRHHKFDLYHGSQWWALSKECLTELIQMYEQNQQDYLNFKIGM
                     FAPDEKFFHTLFFNSSFKNKNVIGGPDLPLELKNIEETTLQTSKLANIHIIDPSMNKW
                     FDERDIDQIKESEKLFVRKVKSDYSDKLLNRIDKEILKVGNIDE"
     gene            27412..28845
                     /locus_tag="RD451_001567"
     CDS             27412..28845
                     /locus_tag="RD451_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HDT7566833.1"
                     /translation="MNRIVPVLEKSLLSRDAFRVINLIICLLYFMPSTFNVTNIPMKI
                     AFAWGGIIVLYEVFIKKNFFKMRFSWLLIGAMISFILTIIINRENFLIPSIYNFGYLL
                     ITLIVIFPADFSQSEEEKKKKMVYFNNVFIIIIFLAALISIYQFIFLISYHVPTGTPG
                     LLARQGFIEHRLFGVYTSPNVGAMFGYTSIILSLISVLISKITKTIRVFYMMNFIVQI
                     FYITLSSSRGAQVVICSFLVLFLLLFANSKFRKSIREVLPVKIKWMVSILLVLLVYFS
                     FGTNYAKDFLATIPVSIDRKVEVIESNESDKTPLPEKEVILQHSSDNSEISAGRFTIW
                     KAALKVIRPTLLFGYGETDFYGNSDAKFLKKVDLDTTDVNELKRAHGNMHNGFLQVLV
                     SSGIIAFICIYAFYVLNIFSLLKTFFRSKVNYAFLGIVLIFILSIFIDEMVEAHVLFN
                     KRDVISIVFWYYLGSISYLYLKKGELI"
     gene            28842..29912
                     /locus_tag="RD451_001568"
     CDS             28842..29912
                     /locus_tag="RD451_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566834.1"
                     /translation="MKTAFIAWTPLHLINILNVYQNFYRESKGDLFIYSEFENARRYS
                     ERIKELGLFNDVVFVNHRKIGSSFKRKINLLTNHNQFFSDDLSVYDEIFIQGENYFTK
                     ILFSNVYKKNPDVKLNYIEDGLGTYLKKSIFSTSKNVQRVFKILNKNSIFKKKIDDYF
                     VYCPELLLYDVKNIKKIPKIDENSKLMKNIQSIFGIEEVFVGDKCIFFDQPLLSDGYG
                     IDETDIFAKVNSIFSGKKETLIKLHPRARTNRYGEKNILNSSLPFEVLLLENDFSSTL
                     LISPISTISFSPSMMFEKTINSIMLAKLILNEYTALSEDKKETLTNIVLFCEHYNRLS
                     EEKILLPENWAELRKLVEYGII"
     gene            29899..31320
                     /locus_tag="RD451_001569"
     CDS             29899..31320
                     /locus_tag="RD451_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HDT7566835.1"
                     /translation="MGLFNTLSKSKLVKSSFWYTIGNFFIKGISFITIPIFVNITTQA
                     EYGLINNFTSFVSIFSILVGLSLNSAINNASFDYKDDINEFMSSVLSLATLSLIVFLL
                     IGNIYFLFSNAFFDMNQLVFNLMLLQSFASFVISYIQSYFTINFNHFKYLILSFISTF
                     LNIAISVALMQTLYFDDKYVGRVVGGTLSFVLIGLVIYLRIMIKGAHFFDKKQWRYAL
                     KISLPLIPHSLANIVLAQFDRIMINSYLGPAAGGIYSYISNIGIILSVIWMSTNNAWV
                     PWFYGEMSKNNEKKVKKVSNYYLVVFTLITMIVMVVSIDLAKFMAPKDYYSGLSLVVP
                     ITLGYFFQFLYSLPVNAEFYEKKTSFIAIGTVASAIVNILLNMIFIPRLGIIAAGYTT
                     VFTYFLLFIFHYNIAKKITNKQLFDTKKICIIIIFVSIFSLILHILINQMLIRYVLTS
                     LLIISLVIYFLKIKNRIIDDYNS"
     gene            31333..32340
                     /locus_tag="RD451_001570"
     CDS             31333..32340
                     /locus_tag="RD451_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HDT7566836.1"
                     /translation="MFKGKTILVTGGTGSIGSEIVRQLLKYEPKAIRIYSRGEEKQFY
                     MQQELSNHTNLRFLIGDIRDSQRIDYACRDVDIIFHAAAMKHVPASEYNPMEAVKTNV
                     MGTQNVIDAAIKNNVKHFVGISTDKVVSPTNTMGATKLLSEKLIIAANQYKGKTETIF
                     SCVRFGNVMGSSGSVIPLFSKQIKNNKDITLTDVDMTRFMMSIPDAARLVLSAAMNSK
                     FGETYVLKMPAINILTLAQSLIKIYNDTHDEKYRGEIKVVGIRPGEKLYEELMTTDEI
                     ERSYENDKMYIIPPHYHATDELYKDYEKIKITAYSSDATELMSGQEFIRIAKENNVVT
                     W"
     gene            32352..33356
                     /gene="neuB"
                     /locus_tag="RD451_001571"
     CDS             32352..33356
                     /gene="neuB"
                     /locus_tag="RD451_001571"
                     /EC_number="2.5.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate synthase"
                     /protein_id="HDT7566837.1"
                     /translation="MKSEVYVIAEIGVNHNGSLDLALESIDKAKECGANAVKFQTFKT
                     NKLVSKKAPMAKYQKDNLKEDSSQFEMLKKLELSQSDFIRIKDYCIQNKIDFLSTPFD
                     EESADFLKQIGVQGFKIGSGDLTNLPFLRKIDMYGLPVLLSTGMADIHEVSEAVDCFI
                     DSPVTILHCTSNYPASSEDINLLAINTLKEMFGIPVGYSDHSLGYDVGICAVAMGAKV
                     IEKHFTLDKELPGPDHKASLDPQEFADFVKHIRNTEIFLGDGVKRAMPSELSTKEVSR
                     KSLVVTENLNVGDILTEKSLTIKRPGNGIAPKFLYQYIGKKVKRPISADSVLLEEDVE
                     "
     gene            33353..34501
                     /gene="neuC"
                     /locus_tag="RD451_001572"
     CDS             33353..34501
                     /gene="neuC"
                     /locus_tag="RD451_001572"
                     /EC_number="3.2.1.183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (hydrolyzing)"
                     /protein_id="HDT7566838.1"
                     /translation="MKKILIVSGTRADYGIYKPVAENLLQDNWDVSFVVSGMHLSHKY
                     GFTKELILADGFRISGEVQSLFLENNKGNMARSVALEINGFTNIFEQTSPDFVLLLGD
                     RGEMLAAAIACLYLGIKTAHIHGGEVSGTVDESIRHAITKIASVHFAATEKSKERLIK
                     MGEDSWRVFPVGAPRIDTILNNRLPSFRDIKEKYHLKFEKKKYVLQVFHPVVTELENI
                     EKQILALINSMEQQSQPIICILPNSDAGSEIIRKMYQKYLKTDIIYITNLEPEEYLTI
                     LKECKFMIGNSSSGIIEAASFKIPVINLGTRQNGREQSKNIINANLNENEIETALNKI
                     QDPQFIKSLKNVKNIYGDGNSSRRITKTLNQILNDGEDIKWIQKQIAY"
     gene            34474..35151
                     /locus_tag="RD451_001573"
     CDS             34474..35151
                     /locus_tag="RD451_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HDT7566839.1"
                     /translation="MDSKTNSLLKYTSDPYIIIGAGGHAKVIIETLRLENKLIYGFFD
                     DKQNKMQDLKYLGKINELNSWADSKKKIYKFIVAIGDCVVRKKIIKKLNMPSEQYGIA
                     VHPSAIVAKEISIGYGTVIFANAVINPDAVIGEHAIINTGSIVEHDCRINNYVHLSPG
                     VCLAGGVHVGVGTQIGIGSQCIQMKKIGSWCMIGAGSTIVKDIPSHSLAYGNPAKIKK
                     EGINFEF"
     gene            35141..36283
                     /locus_tag="RD451_001574"
     CDS             35141..36283
                     /locus_tag="RD451_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDT7566840.1"
                     /translation="MNSRILLSSPHMGGTEEKYVAKAFKDNWIAPLGENVDKFEESIT
                     KYTGSKGGASALSSGTAAIHLALRLLNVGKNDIVFAPSFTFIATVNPILYQGAVPVFI
                     DSEPNTWNMSPVALESALEEAERNNQLPKAIIVVNLYGQMADYERILAIANQFNVPVI
                     EDAAESLGSTYKGISSGLFGTIGIYSFNGNKIITTSGGGALVSSDKKYVEHSRFLATQ
                     ARDQAPYYQHSEIGYNYRLSNISAGIGRGQMEVLNDRVAKRREIFNRYKEAFSGIDRI
                     EMMPEVDGMVPNRWLSTLTINDYNSIDQVVNVINKLNEKNIETRALWKPLHLQPVFQG
                     VKMYYHDNNLSVSEKLFNSGLCLPSGSNMTDSEQEFVIDEFKKIFK"
     gene            36296..37273
                     /locus_tag="RD451_001575"
     CDS             36296..37273
                     /locus_tag="RD451_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDT7566841.1"
                     /translation="MNIGIIGLGSMGKRRLRLIQEHFNDILLCGVDTNEARRKEVEKE
                     FGIPTYNSLTEAKNLFEINSVFVCTSPITHEFIIKEALNLDCNIFTEINLLNEYYDEI
                     IEVAKKKDRLLYLSSTFLKRKEIQYIKSKVTHNKKISYQYHVGQYLPDWHPWEDYRNF
                     FVSNKKTNGCREIFAIELPWIIDTFGKVKSFTVMTQKLSNLDIDYSDSFTLIIEHETG
                     IVGTLSVDVVSRVAKRNLTIIGEKILIEWEGNPDSLFSWNEETSSMTDIQLYDEVMHD
                     NNYSHTIIEDAYLEEIKEFFTLLEKKMEPQYTFEKDKYIINLINDIEVN"
     gene            37273..38181
                     /locus_tag="RD451_001576"
     CDS             37273..38181
                     /locus_tag="RD451_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HDT7566842.1"
                     /translation="MMKVIFFGLGSIGKRHLKNLISYGKKNSINFDITAYSSSGKKEF
                     EEITYIQNRDDLDTHYDIAFITNPTFKHLETLNVIVEKVDYIFLEKPAFSESIDLTQY
                     NYDYKNIYVAAPLRYKNIMEVVRNSIQSKKVYSVRAICSTYLPDWRKGTDYRNNYSAF
                     KSMGGGVELDCIHELDYIINLFGFPKSVKKQFGKYSNLEINSNDLATYILRYDDKIIE
                     IHLDYFGRVPTRKFQLFTLDECINVDLLNNKISFEENIVKEMPESANDMYEKELKYFF
                     ENVVTGKENWNDLYHANEVLKIAEEK"
     gene            38182..38934
                     /locus_tag="RD451_001577"
     CDS             38182..38934
                     /locus_tag="RD451_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HDT7566843.1"
                     /translation="MEILFTICGRAGSKGFKNKNLKYLAGKPLVHFALAMIDIYQQKH
                     PEHNCTTCLNTDSNELVELTTKLNPSVKIVERKPELATDTVGKIEVIRDSFLQLERED
                     NIFDLIIDLDLTSPLREVSNLEELIDEHLKNLDKDVYFSVVSARRNPYFNMVKRIENE
                     VTIVNKSRYTSRQQTPEVFEMNASMYSFKPEFLKKSNYIFDGQCGIIKMRDYLILDID
                     SEEDFKWLEFLFPKFLEDSSELQDIYNYLYRR"
     gene            38939..39886
                     /locus_tag="RD451_001578"
     CDS             38939..39886
                     /locus_tag="RD451_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HDT7566844.1"
                     /translation="MSCYLITGGAGFIGSTLANHLGEEHVVIVVDDLSMGKVENLDMT
                     KNITFIEGDVAEKSLMEEIMKANKFDYIFHLAAVASVADSVARPVETHRVNFESVLMI
                     LELIRKYQPDLKRIVFSSSAAVYGDEPTLPKKEESVIRPLTPYAVDKFAAEQYVLDYC
                     HLYDVPGSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQIVGEATSFTLFGDGSQSR
                     DFVYIDDVIQALLLVANEEAALGKQFNVGTGKATTLLELIHAINEILGVELTLEYKEE
                     RSGDIHDSLADITKIQSIGYQPKYGILSGMTNYLKTEIN"
BASE COUNT        13342 a         6089 c         7806 g        12736 t
ORIGIN      
        1 aaaaaacggt ggggttgttt agcgaaataa aggatctaag ccaatagctt agatccttta
       61 ttctatgctt tatattattt tttgcatgtg tgcgaaagta tactcaagcc caatcgccat
      121 ttcggaaaat cggtactgta gagccatctt cacggattcc gtcgatatcc atcttgtcag
      181 atcctaccat gaaatctacg tgggtttgac ttctattcaa tccagcttct gctaattctt
      241 catcggacat ttctgtaccg cctttcacac tgaaggcata agcagaacct agtgctaagt
      301 gattcgatgc gttttcatca aataatgtat tgaaaaagat gatgccagat tgagaaatag
      361 gtgaagggtc aggtacaagt gcgacttctc ctaaacgacg cgcaccttca tctgtatcaa
      421 gcagttttgc taagacatct tctccttgtt cggcagaaaa atcaacaact tttccatctt
      481 taaaagtaaa tttcataccc gagatgatgg tgccagcata actcagtggc tttgtacttg
      541 aaatgtaacc atctactcga tgactgtcag gtgctgtgaa cacttcttcc gtcggcatat
      601 ttgccatgaa tttttctcca cgagcattat agcttccagc gccttcccaa agatggtttt
      661 taggcaatcc gataatgata tctgtaccgg gagcagtata gtgaagggca gaaaattgtt
      721 ctcgattcaa ttcttctgct ttttttgcta atttttcatc atgcttcttc catgctaaga
      781 cagggtcttc ttcatagaca cgagtcgttt tgaaaatctg atcccataat gcctcaactt
      841 gtttttcttc tggcagttct gggaagactt ttgctgccca ttgtttacca gccgcagcca
      901 cgacagtcca actgacttta tttgcttgag ttgccttgcg taaattcatt agtgctttgc
      961 cattcgctga ttgataagac gctactcgat ggctatctac accagcaaat gcatcgggat
     1021 cggcagaaac aacgctgatc ctgcttgctc ctttttcaag ccattcatcc gcttgatcga
     1081 ttttagattg tggtacattc tcaatacgat ccgttgcagc atgtaaaaga aattctcttt
     1141 ggatctggtc gtcagtccat tgaacgataa cctcagcggc tcctagttta taagcttctt
     1201 gtgtgatcaa tcgagcaagg ggtgcctgtt ccacgctgat ctgtaaaaca actgtgtgtc
     1261 ctttttctgt ggctacgcca gtttctgcaa ttaagcgtgc atattttttt agaagttcat
     1321 taaaatcaga taacataata aaaattcctc ctcaccattt tttctggtaa ctattagcat
     1381 gataccattt aattatgatt caaacaatga ggctttaaat aaaaaaagga ggttattttt
     1441 ttaaggttaa gtttcatgat atatgttact acttgctatt tcagcttgtg aagaaaatca
     1501 aaaactaatt ttgcatatca aaaaaaacat gttacaatga aattaatcaa tggtggaagc
     1561 gttataaaaa aattaaggag attaaaaaat atggcaagaa aaaagacgat tactagagaa
     1621 cagattttgg cagctgctta tgaagtagct gccaccgatg gatttacacg atttactgcg
     1681 agaaacatcg cgaacaaaat gaattgttcc acgcaaccga tttatcttga gtttaaaaat
     1741 atggatgact tgagacaagc tctttttgag cagatctatg atcatttaca atatgaagtg
     1801 ttcactgttg agcatacagg gaatacgatt atcgatcttg cttttaatta tatccatttt
     1861 gcaagaagag agaagaagtt gtatcgttca ctgtacttag aagaatatgg tggaggaaaa
     1921 gagatgcaga atttctctta tacttacttt gtgaatacag tgaaacgcga tccagcttat
     1981 gtgaatcttt cagaagagca gatcgaatct ttgtataatg ggacatggat catagctact
     2041 gggatcgcag ctttgatgtc ttcaagcatc atccatccaa ctgatgaaca gattgaaaag
     2101 atgatccaag acagtataga tgctatcttg aaattcaaag aaccaatcga aatcgattga
     2161 atatactcaa aagttccaca aatcagtagg taacaagaga tgtgtcaaaa taaggaaaag
     2221 ttcgtttttc ttacagcgta tgcattttta actcccgaag aactcttcca tgaatgcaat
     2281 gaataaaaga gccatacaga ttgaataaat ctggatggct cttttattgc aagtatatta
     2341 aatttttgcg actagttctt tagcgaaagc ttctaaattt tcgatatctt cttcttcagc
     2401 attcagatcc actttaacat tttcggctcc ttttgatgcg cctgtttttg caaaagcagc
     2461 atcgaaatca tccaccgatt tgcagaattc atcgtaaaaa gtatcaccag atccgcagac
     2521 accgtaaatt tttcccaata gatccaattc ttgcaagtct tcataaaagt ctacgatctc
     2581 atcaggcaga tcgccatcat cgtatgtata agtagctact acgcaaatat ctgcctcctc
     2641 gaattcatct gcatctactt gggtacattc gttgatttcg acttcgatat ccagattttc
     2701 aaatgcttct gcaacaatat cggcgatttc ttcagtgttt cctgtcatgc tagcatatac
     2761 gatttttgct aaagccatga tgtgcctcct cgtttataat tatttaacaa ttatgaatta
     2821 taccaaaaca tcattgaaaa gaaaataaaa cctagagaca cctggggaat gtcatttggc
     2881 taaatgtatg ccgctatgtt aaaatgagag ggatttgtaa aaaggagacg aaaatatgat
     2941 tactttaaaa tcagcacgtg aaattgaaat gatggcagaa tctggagctt tattagcaga
     3001 tgtacataaa aatctgcgtg attttataaa accaggaatc acaagttggg atattgaggt
     3061 atttgtcaga aactatatcg agagtcatgg cggaattgct gcgcaaattg gctttgaagg
     3121 gtatgaatat gcgacttgta tcagtataaa tgatgaaatt tgtcatggat tccctcgtaa
     3181 aaagcctttg aaaaacggtg atttggtaaa agtcgatatg tgtatcgatt tgaaaggcgg
     3241 catttctgat tcttgttggg cctatgtagt tggagaatct acacctgaga tcgaccgatt
     3301 gatggaagta acgaagaaag ctttgtacat cggtattgag caagcacaag tagggaatcg
     3361 gattggtgac atcggtcatg ctatccaaac ttatgtagaa ggcgaaaatc tagcgatcgt
     3421 tcgtgatttt attggtcatg gcgttggtcc tacgattcat gaagaaccag cagttcctca
     3481 ttacggagaa gctggaaaag ggttgcggtt gaaagaaggc atggttatca cgatcgaacc
     3541 tatggttaat accggaactt ggaaaatgaa aatggatcct aacggctgga ctgcgtatac
     3601 aagagacggc ggactttctt gccaatatga acatacattg gctattacta aagatggtcc
     3661 aagaattttg acatcacaag gagaagaagg cacttattga tctatccagt caataggtac
     3721 gggagaggta catgaaagtt tggaacaaaa taaaacaaaa tgaaaatctg atgcgcttta
     3781 ttgagacgac tcaaaagcgc atcactgatt cagaaatgag tacgacctct gtcgtcgttg
     3841 cttattattt actcttgtct ttatttccat tgattattgc ttttggtaat attttaccgt
     3901 ttctccacat cgatcaagag actgtactga cctatttacg agaagtgatt cctgagaccg
     3961 tttaccagtt tatcggtcct gcaatcaaag accttttgac acaaagttca ggaggcttgt
     4021 tatccgtttc tgcattagcg gctttatggt ctgcaagtca aagtatcaat gctttgcaaa
     4081 ttgcgatgaa taaagcgtat ggcgtagaaa atagaaaaaa ttttttgatc gtccgtttct
     4141 tctcactaat tgtcattgtc ttgttcatga ttgctattag tggggtaact atcgttcttg
     4201 ggttgggaca gctgattttg gatgctattc agccaatcgt acaaataccc gtgaacttta
     4261 tcgatcagtt ccaaactttg aagtggccaa tcacattggt agctttattt gtcatcatgt
     4321 tcttgattta tttaattgtc cctaatgctc agttgaagtt gaagacgatc attccgggca
     4381 cgatcttcgc tactgtcggc tggatgctgt tatcacaagt gtttagtatc tatgctaggt
     4441 attttgcaac gaggatcagc ggttatcaga tcataggaag ttttattgta ctcatgcttt
     4501 ggcttaattt tgctgctacg atcatcattt tgggcggaat catcaatgca gttgttcaag
     4561 aatacgtgac gggtcatcaa atcaaaaaac gtcgagatcc aagccgaaaa tggttcaata
     4621 aattgaaaac taaattttct cataaaaaaa agtagaaaca agagttctta ttgtaaattt
     4681 atatcagtaa tttataataa ttatgactct taattaaagt aggtgcccat atgcttgttt
     4741 cttttagtat ggttataaga ttttttctga caattttatt atcactgata ttaacacctg
     4801 tattcaaaat catttcagta caaacaggta tggtcgacaa accaaatgaa agaagaataa
     4861 ataaagttcc aatgccttca gcgggcggac tgcctatctt tatttcattt gttatatcga
     4921 ctttattctt attccgtaaa attatccctc aatcgtatat tgtaccgatc ttgattgctt
     4981 ctttagtaat catagtcaca ggagtgctcg atgataaata tgagctgaca cctaaacaaa
     5041 aaagtatagg gatcttgatt gcttctctta ttatttattt tgtagcagat atacgtattg
     5101 attccttcac gcttcctttt attggatata tccaactagg ctggcttagt tttcccgtaa
     5161 cgattttttg gatcttcggt atcacgaatg cggtcaatct gattgacggt ttggatgggc
     5221 tggcggcagg gatttcattg atcggtttaa ttacgatagg aatcattgga tattttttcc
     5281 tccatgcttc tacagtgtat attccagttg ttattttctg tcttgtagca agtattatcg
     5341 gtttttttcc ttacaatttt tatccggcaa agatttattt aggcgataca ggagctctat
     5401 tcctagggtt tatgatggcc gtcctttcac tacaagggct gaagaacgtg acttttgttt
     5461 catcgatttc tttgctgatc gtcatgggag tgccggtaac agacacgttt tttgctatca
     5521 ttaggagaaa agcaaaccgt gtttcttttt ctacagcaga taaaaaacat cttcatcacc
     5581 gactaatcag tttaggcttt actcataaag gtgctgtcct gacgatttat gcgatggctt
     5641 tgatgttttc tttcacagct atggtcatga attatactgg aagaatcgga acgatcatat
     5701 tgattattgc catgttgttt gctgcaattt tattatttga attgattggt ctgatcaatg
     5761 agaaacatca gtttatttta aaaacattgc gatttttagg gaataaagag taccgtacgc
     5821 aagtaaaaca gaaatatttg aagaaatgga accgtcatat agatgaataa caaattaaac
     5881 cagccgatcc ttattagtat tgtgacggca aacagtgata aaatttttcg gacactagat
     5941 aattttattt caactgtaaa agatgaaaca gcagtaaaaa tccgaatttt tgacaacaat
     6001 tcacttcccg agtacaaaaa aagactaaca gagtatagga aatatcccta catcgatatc
     6061 tattttcatg atgaaaattc cggatttggt tatggacata atcacaatct gatagctagc
     6121 gattctcgct atggcattat ttgtaaccca gatattttag tggatgaaga gacagttaca
     6181 gcattggtct tgttattgaa agaacatccg gaatgtgcga tgttagcacc taagattctt
     6241 aatgaagatg gaacaactca gcacctcatc cgtgagcagc tggctgtttt tgattacgtt
     6301 ttgcgctttg tgcctttcaa atgggtcaaa aaaaagtttg acaaacgact ggctgtgttt
     6361 gaatgccgag gattgcctac tgatgctaat agttatgtac ggatgatctc aggtagtttt
     6421 atggtagctg atattgataa atttaaagag ataaaggggt ttgatgagcg tttcttcatg
     6481 tactttgaag acaacgactt gtgtttgagt tttgaaaaag caggttacaa gttattgtac
     6541 acaccctttt atgcagttat ccatttttac gggaagggtg cgcatcgaaa tgcaaaactg
     6601 tttcgcgtgt ttttgacttc tatgatgaaa tttttcaata agtgggggtg gcgttttttc
     6661 tgatgaaacc agaaatatta gtagtcgttg tgctttatca gcaactattc agtcaatctc
     6721 cagcttatgg accattaagc aaagcactta gcgaaaagca aattcagctt attatttacg
     6781 ataatagtcc tcaaaggcag caaaatgagc tgtttgaaaa agaaaatatc gtttatcatc
     6841 atgatccgca aaatcctggt ttagcggtgg cttataattt tgcgttgtct caagcagatg
     6901 aaggaacacg ttgtctcgtc actctggatc aggatacgag gctagtcgac gattattttg
     6961 aactattgcg taaagtaacc tttacagatg aatgtgttgc tgcagttccg atgatttttt
     7021 ctgggagccg acaagtttct cccctatatt cagatcgtta tatcaatcgt acagctcaag
     7081 cagtagaagt tgaaggccca acagctgaac gaatcatggc aatcaattca ggtgttgcct
     7141 ggtctgtcaa atttctaaaa aagattggcg ggtttaatcc tgctttttct ttagattttt
     7201 tggatcattg gctgttttgg aaagtggatc agttggaaaa aactgtggag atccttcctg
     7261 tacgaatgga acatgatctt tcggttttag actatgaaaa agtttcaagt aatcgatacc
     7321 gttctatttt acaagcagaa aatcgatttt atcatgaata tgatcaaagg catttatcca
     7381 gtcaccgacg acaattattg ttaagaacag ctaaacagtt cttgaccgtc aaaaaccggc
     7441 atatctggcg gatgactttg cgctcatatg ttaagaattg gaaggtgtga attcgtgcgt
     7501 tcggtttgta tagctacctt taatggaggc agatatttaa gagagcagtt agatagtatt
     7561 ttatctcagc tttcagcaga agatgaagta gtcatttctg atgatgggtc agtagatgat
     7621 acatgggata tattaactga atacgcagaa aaagataagc gaatccagct tttttcgggg
     7681 cctcgtcaag gattgatcgc taattttggt tatgcgatcc agcagacgaa aggagatcta
     7741 atctttttgg cagaccaaga tgatgtttgg ttggagacaa aagtgaaaaa gatcactgac
     7801 tattttgagc agaatccgga tcagctagta gtagtttctg atttaatcat tgtggacagc
     7861 gagctgcaag agatccatga ttcgtatttt tcgtttcgaa attccaaaga aggatggctt
     7921 aataatgtga taagaagtca ctatattggt gctggtatgg ctttccggtc ttctttaaaa
     7981 cccgatattt tgccgatccc gtcagaagtg ccgatgcatg atatgtggat tggtttgctg
     8041 gggggaaaga agactgggtt cctaagagaa ccgttaactc tgtaccgaag acatgattta
     8101 aacgcgagtg agattgaaac acattctaaa ttacggcaaa aaatttcttg gcgtgttcat
     8161 ctgattacgg cgttgatcaa acgaaaatgg tttaaacgtt gataaaagat gtttaaatcc
     8221 ttaatatttc catgacaaat ataacaattg atgagataat aacaaagtga aatttgaaat
     8281 caaaaaggag agcagatatc catgaaggga atcattcttg ctgggggcag cggaacacgt
     8341 ctgtaccctt taacaaaggc aacatcgaaa caattgatgc cgatttatga caaaccaatg
     8401 atttattatc caatgtctac tctgatgttg gcgggaatca aagaaattct gattatttca
     8461 acgccacaag atacaccacg tttcaaggaa ttatttggaa acggaaatga tttaggactg
     8521 cagatcgaat atgcagtaca agaaagtcca gatggattgg cacaagcgtt tatcattgga
     8581 gaagaattta ttggagatga tagtgtctgc ttggtattag gggacaatat ttactatggt
     8641 ggcggtctgt ctaaaatgtt gcaacgagca gcttcaaaag atacaggcgc gacagtattt
     8701 ggctatcatg tcaatgatcc agaacgcttt ggtgtagtag aatttgatga gaatatgcaa
     8761 gctttgtcga ttgaagaaaa gcctgctcag ccaaaatcaa attacgctgt aactggcctt
     8821 tatttttatg acaatgaggt aatttctatc gctaaaggta tcaaaccttc agaacgtgga
     8881 gaactagaga ttacggatgt caataaagca tatttggata aaggaaaact atccgtagaa
     8941 cttatgggac gcggatttgc ttggcttgat acaggaacac atgaatcatt gcttgaagca
     9001 tctaccttta tcgaaacaat tgaaaaacgt cagaacttaa aagtggcttg tttggaagaa
     9061 attgcttacc gtatgggcta catcgataag gaacaattgc tggcccttgc acagccattg
     9121 aaaaaaaatc aatacggtca atatttattg aatttggccg ctgaataagg agtccttaca
     9181 gatgaaagta acagatacaa aattaacaga tgtcaaaatc gtagaaatgg acgtctttgg
     9241 cgatcatcgc ggtttcttca cagaaagtta ttcaaaagca aaatttgcag aacatggatt
     9301 gaaatatgac tttgttcaag acaaccattc actatcagct gaagctggtg tccttcgggg
     9361 gcttcatttc caaaaaggag aagctgcaca gacaaaattg attcgggtag tcactggagc
     9421 agttttagat gtagtagtgg atatccgcaa aggtagcccg acttatggtc aatgggacgg
     9481 atttatctta tctgaacata atcatcgaca gttgcttgta cctaaaggat atgcccatgg
     9541 attcgttact ttgacaccaa atgtgaactt cctttataag tgtgataatt actataatgc
     9601 agaagcagat gggggcatcg catttgatga tccagattta gcgattgatt ggccaattga
     9661 tccatcaaga gcgattatgt cggaaaaaga tcaccgtcat ccgacattaa aagaatttga
     9721 agcagaaaat ccatttgttt acggagaaat ctaagaatta aggagaaatt ttcttatgaa
     9781 aaacatcatt gttaccggag gtgccggatt catcggctct aatttcgttc attacgtggt
     9841 aaacaatcat ccagaagtgc atgtcactgt tttggataaa ctgacttatg caggaaacaa
     9901 agagaacttg gctggacttc ctagcgatcg cgtagaattg gtcgtaggag atgttgcaga
     9961 tgcagaatta gtggaccgtc tagtaaaaga agcggacgca gttgttcatt acgcggcaga
    10021 atcccataac gataattcat taaaagatcc tttcccattt gtacaaacga atatcattgg
    10081 tacgtataca cttttagaag cttgccgcaa gtatgatgta cgctatcatc acgtatctac
    10141 tgacgaggtt tacggcgatc ttccattacg tgaagacctg ccaggacatg gggaaggcga
    10201 aggagaaaaa ttcactgcgg aaacaccata taatccttca agtccatatt cttctacaaa
    10261 agctggttca gatctgttag taaaagcatg ggtgcgttct tttggcttac gtgcaaccat
    10321 ttcaaactgt tcaaacaact atggtcctta tcagcatatt gaaaaattta ttcctcgcca
    10381 agtaacgaat atcttaagcg gtattcgtcc aaaattatat ggcgaaggaa agaatgttcg
    10441 tgactggatc catacgaatg atcattcttc agcagtgtgg ctgattttga cgaaaggcag
    10501 aattggcgaa acctatctga tcggtgcaga cggtgaagaa gataataaga ccgtgatgga
    10561 attgatctta gaaatgatgg gtcaaccaaa agatgcgtac gaccatgtaa acgaccgtgc
    10621 aggacacgac ttgcgttatg caatcgattc gacaaaatta cgggaagagt taggatggaa
    10681 gcctgagttt acgaacttcc gtgatgggtt ggctgacacg atcaaatggt acgaagaaca
    10741 tgaagactgg tggaaaaaag aaaaagaggc cgttgaagca gcatatgcca aaaatggaca
    10801 ataatacaga gaaaatgtca ctgtattaat ggaaaaacac atgtgaggca ggcgctcgcc
    10861 tgtctctttt ttaaaataaa aatcaaggag cggataatca tatgttttta ttaactggag
    10921 gaaatgggca actaggtaca gaattgcgcc atttattaga tgaaaaaaat ctgcaatatg
    10981 tttcaacaga tgcaaaagac ttggatatca cagatgccga gaaaacaatg gcttacatca
    11041 cagaattaaa acctgatgtt attttccatt gtgcagctta cacagcagta gataaagcag
    11101 aagaagaagc aaaagaatta gatgagaaga tcaatgttga tggtacaaga aatgtagcac
    11161 ttgcagcaaa agctgtgaat gctcaattcg tctatatcag tacagactat gttttcgatg
    11221 gaaaaaacaa aaatgtagaa tacgaagtag acgaccaaac gaatccacta aatgaatatg
    11281 gtcgtacgaa attattaggc gaaaaagcag tagaagagat tttagaagac tattatatca
    11341 tacgaacttc ttgggttttc gggatctatg gacacaattt cgtcttcacg atgcaacgcc
    11401 tagcggaaac ccgcgacaaa ctgactgtag taaatgacca gtttgggcga ccaacttgga
    11461 cacgtacttt ggcagaattt atggtatatg tcatcgaaga aaaagcacca tttggtattt
    11521 atcatttgtc gaacgaaaat agctgttctt ggtatgaatt cgcaaaagaa atattgaaag
    11581 atacagatgt agaagttgca cctgttacgt cagaagaatt tccgcaaaaa gcaacacgtc
    11641 cgcagtattc agtcatgagc ctgaaaaaga cagaagagtt aggatttgtc ataccaactt
    11701 ggcaagaagc acttgcgcaa atgctggaag ctgccaaaaa aatgaataag taatttcctt
    11761 ttatcaaata gaatttggag catgatatgg aaaaacaaac aagaagtgca cgacgaaaag
    11821 aaaagccaaa agcgaaccag gcagattcga atttggtgct tgacctgttt ctaaaactcc
    11881 gctatcttat tggcgtttta gtcatcgtgg tcatcgttac ttttaattta aacggaagtt
    11941 cacttggtgt ttgggataaa tatgtgtcgc aaagagacga tgggaaaaaa actgatgtga
    12001 tttttggaca gaatcgggaa gtgcggtcag acgaatggct ggtgcagaca cctttttacc
    12061 tctcacaagc tgaagaggac tttccgttgg tgaacgagga ttattcatta aacggacaaa
    12121 acatgatcat tgcgtataat tctcctgtaa aggatattac ggttatcgga aaaccattca
    12181 actggggatt ctttttcctc ggaagagatc gaggactttc cttttattgg gcgatgaaat
    12241 tagtcgtcat ggtcttgctt ggattcgaag tactgatgat attaacgaag agaaaaaaag
    12301 ctctatcgct aatcggtgca tttgcgctga cattttctcc agcagtccag tggtggttca
    12361 tgcaacatgt gggcgatttg attttcttta ctttgggact gatgactgct ttttatcatt
    12421 atttctacaa tcatgataaa aaatggctac gaacgttgat gatgcttttg gtggttattt
    12481 tcggtattgg gtttatttta gtgatttacc cagcccatca agtgatgctg gcgtacttgc
    12541 tgatttttta ttttgttggc ctgcttattt actatagcaa gaaagtttca tgggatctgt
    12601 tggatgtagt gttgattgga ggggcagttt tatttattgg cggagtcatg gttcatttct
    12661 ggctaacgtc aaaagacgca ttgttagctt ctttgaatac cttatatcca ggaaaacggg
    12721 taagtactgg aggaaagtgg acgattggcg aatttttttc tttccttaca aattggaaaa
    12781 ttccttttga agatatcaac tattcgaata actctgaagt ggccctgttc tatcactttt
    12841 ttccaactgt attcctagca agtccatttg tgttatttgg caaaaaagat agcgaacaaa
    12901 agttactggg acgtattttg atgatttttt gtctgttttc tatcttttgg attaccgttg
    12961 ggttgccaaa atggctagca gaaatcactc tgctgtctta tgttcctcca ttaagagcca
    13021 tccttacttt tagttttgcg gcttgtttat tatcgatctg gtttatcgct tatatttgga
    13081 gagaagatgt tattcctatt tggtataaat tcattttgtt ggcagtaaat gcatggtctt
    13141 atttctatgc gattacgcat tcgaaaatgg ataattattt ttcggatttt gaaaccatcg
    13201 cagttgctgt gttgggaaca gtgattttag cttttgcatt atttggctgg agacgcttgt
    13261 tttacctcgc ttttgccgcc ttagttatcg tatctggctt tttcgtcaat ccagtcgtag
    13321 aaggtacagg agcgattttt gaaaaaacac tggcaaaaga aatccaaaaa atcgatcaac
    13381 aagatcctgg taaagtttgg ttgtctgaag atgaattata taacttcacc ccaacattgg
    13441 gagtgaaatc cttcaataca gtacgctttt atccagatat agctgcatgg aagaaaatcg
    13501 atccgaaaga agaatacgag aagtattata atcggtatgc tcatacaaga gcttttatcg
    13561 ctaaggaaga tacaaagttc attttagatc gtccagatat gttttcggtc acgttgaatt
    13621 ttgaagacgc agaaaaatta gggatcgact atgtgatcag taaacgacca ttaactgatt
    13681 acaaccaatt atatgaagcg cagttcacgc agctatatgg accggataaa gacggttata
    13741 tgatttttaa agtagaatat ccggattatc cagatgtacc acaaacacaa actcaggaaa
    13801 atcagctagt cgtacagtaa taggctagct gagaataatc ctgaaatgtt agtagaaagg
    13861 agagtggaga taattcaagc aatcgtacaa aaatttgtca acaaaatgag tgtcggtttc
    13921 ttgcttttgt tactgacgct agtctttttt gtttggacag cagggttagg ttttccagca
    13981 actttgttta tatataacaa tagttcatta cttatcgctt ttagtgtggc tattttgctc
    14041 attttaaatg tttataaagc aaaaggcgtc gattttcttt atctaggtgt tgcgcttgcc
    14101 cttttcattt tcttttctta ctttcgggaa ttaagaaatg agtctttatt tggagactta
    14161 ctgtttcctt tgattatttt attttgttta gtaattaaat ggatcgagtg gacaaaatgg
    14221 gatcgcggta tttatctgat tgtcttttcg gtcttcctcg gaatcacgtt tatcgtgtat
    14281 ttacagagat ccaagtacca gaaggacaaa gcatctgggc tccaggcaat tcgctttctg
    14341 atatttggat caatacgaat acaatcggaa gttctttgat gactcttgct ttattgatca
    14401 gtggatttgc cagttctttt gaacgatggt atgtacgaat catcggtgca gtagcagttg
    14461 ttgcagcttt tctcgggatt tgggtctgcc aatctagagg tgcattagtc gcgttgattg
    14521 tttttgcgat attggatctt ttacctaaat cgttgatgcg tgtcattcgt gcgccattta
    14581 ttgcttacac ggttacgatt cttttagctt tgccgatttc ttatctggcg gctgtctctg
    14641 aaaaagtcaa tttgtttacc ggtcgagaag atatttggca taaattctat cagacgctag
    14701 gagaaaaatc tgaacaaatt ttactaggaa tgaaaacatt tatcttccaa cgaggaaacc
    14761 aatttttagg aaaccacaat agttataatt ctattttgaa tatctatgga ttgataggat
    14821 ttgggattgc tgctttgctg cttatccttt ttattggtcg cttaacgttg aaagcagatt
    14881 tatccaacgg gcagatgact tttatctggg ccttttttgc ggtgatgatg cagtcattta
    14941 tggaggatac attgacttca taaccatggg ttccgattat ttatatcctg ttggctatgg
    15001 ccgttcatcg atatgatgaa ccagaagttg cggaggaatt ctatgttatg gaagaggcat
    15061 atgacgatat gacttatgat gatacatctt atgaggaaca accagatagc gctcattctt
    15121 ccaggatcca acgctatcat tgataggcac aaaatacgag agaggctgtg acaaccgtcg
    15181 cagccttttt tggtttattg caattgtcta gcatcttctg taaaatagaa acgttagaga
    15241 aaatcttgta tcatagaaaa ttaagaaaga aataagaacg cagctcggta ccaaaaatat
    15301 ggtaaaatgg cacttgactg taattcactg aaaatcgctt ggaggaacac aaatgtttaa
    15361 agatttgtat ttatttatga aggacattta tcagaacaga aaattattgc tacagttttc
    15421 gatcaatgac ttcaaatcaa gatatgcagg atcgttttta ggaatcttat gggcgtttat
    15481 caatccgcta tttactgtat tgatttattg gctggtattt ggtgttggac tgaaagcaca
    15541 aatgatcgat gcaaaatacc catttatcgt atatttagtt accgggatga ttccctggtt
    15601 cttcttctca gatgcatttg catcaactac ggttgttttt cgggaatata cttatttagt
    15661 aaagaaagtc gtattcaata ttcgtatctt gcccacgacg aaaatcctat ccaatctgta
    15721 cacccattta ttcttcattc tgattggcat agctgtcgcg cttataaatg gtatatatcc
    15781 ttcagcaatg tctttacagc tgatttatta tttattttgc atgtgtgctt tcttgacagg
    15841 attgacttgg ctgacggcat cgatccaacc atttttacct gatatcatgc aattaattac
    15901 gatcgtgctg cagttgatca tgtggacatt accgatatta tggagcccta atcagtttga
    15961 ttcaggtctt gtaagcatat tgaaattaaa tccgctgtac tatgttgttc aaggttatcg
    16021 tgagtcattt ttaagtgaag cttggttctg ggagcatgga acatatactt tgtatttctg
    16081 ggttttcacg ttagtaatgt tcgtaatcgg ctctgcagtg ttccgtagat tgaaaccaca
    16141 tttttcagat gtgctgtaag gagaatagct atgacagaat atgcaattag actaaaagat
    16201 atcacaaaat cttataatat gtacgcaaaa ccttcggatc gatttcgtga agccctcaat
    16261 ccttttaaga aatcctatca tgatgtattt tatgcgttga aaaacgtgaa tgtagaaata
    16321 aaaaaaggtg agatgatcgg tttcgtggga gaaaacggat cgggaaaatc tacaatgttg
    16381 aaaatcatta cgggagtact gacaccaaca tccggcacga tggaaatcga aggaaaaatc
    16441 tcagctttgc tagaactagg atcaggattc aatcctgagt attctggcta tgaaaatatc
    16501 tatttaaatg gaatggttct aggattttca agagaagaag tcgatgaaat ggtcgatgat
    16561 atcattgaat ttgctgacat cggagaccat atttatcaac ctgtaaaaac ttattcaagc
    16621 gggatgttcg ttcgtctagc ttttgctgta gcaatcaatg tgaatcccga tattttgatt
    16681 gtggatgaag cattggcagt aggcgatctt gaatttcaac taaaatgtat ggaaaaattt
    16741 acagaaatca agaactcggg aaagacgatt ttattcgttt ctcatgatat cagttcgatt
    16801 cgtcgttttt gtgatcgttc ctattggttg aaaaacggag aagtcgtcga atatggcgat
    16861 acgatggaag taacgacgaa ttatgaaaac tttttaaaga aaaaatcagt taaaacagtg
    16921 gatcggaata aaaaccaagt agaacggttc gccgctccag atatcgtcga cgtgacgaaa
    16981 gcggaattgt tggataaaga caaaaatccg gtggatatgc tggaacaagg agaaaaacta
    17041 tacgttaaag taacttatga agtaaaagat gatacaatca aaaatccggt tttaggaatt
    17101 gcgctacgaa cagtcgacaa tttttatgta tgcggactta atactctact agatggtatc
    17161 aagattcctt ggaaaaaagg agagaatatc ttttatctgg agtatgaaaa gttaggtttg
    17221 ttagctggtg aatattattt tgacgttgcg gtctttgaag aaaatgcaac ggttcctttg
    17281 gtatataaga caaagtacat gaacttgttt gtcagcggtt cttatatcgg agaaggcatc
    17341 gtggtcttag accataaatg ggaagaaggg actcatagca atgaaatatg attttgaaat
    17401 ggacctagat gaacaaagca gtgtgggaaa aattgccgca cagatcaaac caggaagtaa
    17461 agttttagag tttggtcccg gaaacggccg attaacgaaa catttaatcg gagcaaaaca
    17521 atgtgaagtg agcattgttg agttagataa ggaattgttc gattttgtca gcgaatttgc
    17581 tcaagatgga ttttatggtg atatcgaaag ttttgagtgg gcaaactatt atgctggaca
    17641 gacatttgat tacgtcttgt ttgcggatgt tttagaacat ttggtagatc ctggaaaaac
    17701 attgaagaaa gtcagagaat ttttgaatga agaaggagag atcctgatta cattccctaa
    17761 cttggcgcat aattctgtca tgatcgattt gttcaataac caattgccgt gggcttctta
    17821 tggtctccta gatgaaaccc ataattcttt ttatactcat gatggcttcc aaaaagtttt
    17881 tgaaaaagcg ggattattca ttaatattga agattatttg tacttagctg taggtgatac
    17941 agaattaaaa tcaacttatg aagaattgcc ggaagctgta cgctatgatt tcaaaatgcg
    18001 accatttggt gaagtctacc aatacttttt ctcattgatg aaacatccag tagcacaaag
    18061 ttccattgca gagccacaaa attctaatta tgtaaaagtg ttagaagtaa cccagcaaac
    18121 gaaacaagat gaaacaatcc aacaaatacc attcaataat ttcacagggg aaaatgagac
    18181 actaagtttc cccgtatcag aaacaacaga aagaatggtg tttcgcttcg cgcaacaacc
    18241 tagctttatc gaattcagcg cagaagctgc cggagaaaaa ctaacattta tcgattcgaa
    18301 tgctgtagtc aaaacagtaa atgattgtta tttgtttgat gggaaagaat taccagagtt
    18361 cgttctaacg gatatttctg ggaaagaagt gactatccat tgtcactatc gctttatcgg
    18421 ggaattgaca ccaacaatga aagaattgtt ggaaacgatt cgtcccatgg ctgaagtcac
    18481 aaagcagctt tctgagaaaa atgacgaatt agaaagagaa aatcatcatc ttcttgagga
    18541 aaatacaaga ctagaccata cgttaaaaac aaccacaaat cgctattgca cattgttgga
    18601 aagtgatgaa tggacaataa aacatagact aggacgacgt aagaaagaaa cttcgaaaaa
    18661 aatccaagaa aaagaacttt ctatatgtat tgacgagaaa atctgggatg cagaaacaaa
    18721 aatattaaaa atcatcggat ggggaatcgc taattcggat cgccagccct tgtcctataa
    18781 gttatcagct gaccaatcgc catttttcga agcaattcct gtttcacgag aagaagtcaa
    18841 tcaagcagaa cagctcgcaa aaggaacaga agcgggattt gagttacgaa tcctttgcga
    18901 gcaagaacgt tcattcttag tggaagcagt agctcaaaat ggccaatcat ggatcattga
    18961 aatgtaaata atgattaact tataaagata aggagtaaac gaatcgtgca aaaaaaagaa
    19021 attgccgtat ttatcgatca aatcactcgt gaacgggcca ctggcgattt gcttattgtg
    19081 ggctgggcaa ttgatgaagt gaccaaagaa atccctacga taaaggtaga aaaagaaaat
    19141 gtgattgctg aagcaacaca tgtcgtaaga ttggatatca atcatttata taatcttgat
    19201 gttaagaccc aaagcggttt taaggtacgt ttatcaggga aaatgagagg aaaagccatc
    19261 ttagacttcc aaacagcgag acatcaaaat ggcatagctg tgaaattaaa cggtaaatac
    19321 ccttatgatg acggcattga atcttcatgg gaaagaaaaa aaagattact gaaaaaaggg
    19381 ataaattatg caaggactca tggcgtaaaa aaagcgatcc gtcgggtcaa attggaattg
    19441 aagccaggat cgatcgacta tgcagagtgg atcagtcgtc atgagaaacc agatttgaaa
    19501 gagcaaagga aagaagcaca aggatttgcg taccgtccat tgatttccat acttatgcct
    19561 gtctataacg ttgaaatcaa atggctcgaa aaatgcattg attcggtact ggatcaaacg
    19621 tatgatcatt gggaactatg tatcagtgat gatgcttcta ctgatccagc tatccgaaag
    19681 tgtctggaat cctatcaagc aaaagatgat agaatcaaag tcgttttccg aaaagaaaat
    19741 ggacacatca gtctggcaac taattctgca ttggaaatag cagaaggaga atttatagca
    19801 ctcttagata atgatgatga attaccgcca tttgcattat atgaagtggc aaaagtgcta
    19861 aacgtacatc cagaactgga tgtgatctac agtgacgaag ataaaatcga tgcagatggc
    19921 aatcgctttg atccgcattt caaagcagac tggtcgcctg atacattgat gggaaataat
    19981 tatatctctc acttaggcgt atatcgaaca agcattgtta aagaacttgg cggtttccgt
    20041 aaaggctatg aaggttctca agattatgat ttggtccttc gtgtgacaga acaaatccct
    20101 gcagatcata tttaccacat tgaccgagtc ttgtatcatt ggcggacgat cccaggatca
    20161 actgcaagta atggcgaagc caaaagttat atctatgatt ccggagtgaa agcattgaca
    20221 gatgccctgt ctagaagaaa catcaaagga agcgtacgtc ctggcagaat ttctggattt
    20281 tatgagattg cttatgacgt cttgcaagag gatttggtca gtgtgatcat tccaacgaag
    20341 aatggctatg aagatctaaa aacttgtgtg gattcgatca tcgaaaaaac gtcttattca
    20401 aattatgaaa tcattattgc ggataacgga agtacagatc caaaaatgca agaattattt
    20461 gcagaataca agcatcagct gaaagaccgc tttatcgtag aattgattga cattccattc
    20521 aattattctc gaattaacaa tttagcagca gaaaaagcaa acggcaaata ctttttattc
    20581 ttgaataacg atacagaagt gattgagcca gattggatga cggtgatggt ttcttatgca
    20641 cagtttgatc gaatcggctg tgtaggagca aaactgtttt atccagatga tacaacgcag
    20701 catgcaggag tattattagg aatcggtggt gttgcagggc atgcattgaa taactatgat
    20761 cgaacacatt gtggttattt cggccgattg gtcattgacg tcaattactt agcagtcact
    20821 gcagcttgta tgatggtcaa ggcagctgac ttcaatgctg ttaacgggtt tgatgaaaca
    20881 ttagaagtag cattcaacga tgttgacttg tgcttgaaag tttatgaact gggtcgttac
    20941 aatgtctatg cacatcaagc agaattgtac catttcgaat ctaaatcaag aggttatgaa
    21001 gatactccag aaaaacaaag acgttttgct ggtgaaatca aaaaaatgca agataaatgg
    21061 ccagcatata ttgcgcatga tccattttac aatgataatt taacaaaaga aggaatcggc
    21121 gacttttcgt tgagaccaga ttaaactata ataaaaagct gttatgttgt gattcgctcg
    21181 cacataacgg ctttttatag ttttttgtca aaaaaaggca gaaggtgccg actcaaaaaa
    21241 ataagtcgag gttgggacag aagtgtttaa ctccgagaaa taagaagaaa ttcacgaaaa
    21301 ttgcttttca aatttttgtg aatttcggct tatttaagaa gaagttgctt ctgctcccac
    21361 cgtttattcg tttttaaaga atgagacaaa agtgtttctt acttttgtcc cacgctctta
    21421 ttcatgctca gagcgccaat agatacaaaa tcatagccaa agtttcacga accctagctg
    21481 tcaaagaatc gatattttat tttaatatag gctattttaa aataaatggt ttaaggtatt
    21541 cctctacaaa agccactcta tcaattatca tgggtttaaa ataagaagtg atggagataa
    21601 ccagattgtt cttagcgtca atataaagaa catttccact attaccaatt gctgaatata
    21661 tttcgttctc agaatctaat acccaccata aatagccata tctcatattt tgtaagtctt
    21721 ctaaagcact ggttctaggt ttgaacatct cgtttatcca catgggtggt acgatttgtt
    21781 ttcctttata catcccttta tttaggcata atacaccaat ttttgccaga tcacttgccg
    21841 ataaacacaa accatatcct gccgtcccga tatttagtgg atcacaaaac cagacattgg
    21901 ttttaggaga cttatccatt gtaaactgct tatgttcttc agctgtttca gcataataat
    21961 tgacatggtt tggtatccct ataggatcaa atagatactt attggcaaaa tcaacagttg
    22021 ttagcttact tgtctgatac aacaagccag ttaatatgtg taaacagaca gtttgatagt
    22081 tgaattcgcc ggttatacct tttcttcctc ccaataaatc tagtgatgtt tttgtccaat
    22141 cttcacttga acagactttt gtccatggat cgcctttaca tttgtagggt gctttcattg
    22201 ttagcaagtg cttgattgta atagcgtaaa tagttttctc cccgcgtttc actttatact
    22261 ctggaaaata atctaatact ttatcatcga tacttttgat taatccttgc tctaaagcaa
    22321 tgccaatcag caaagataca atacttttcg ttgctgacat gatatgacaa gtatcgtctt
    22381 ttttataacc attccattca tctgtataaa cttctacccc atccttatat gcgacaattt
    22441 gacatatatt tggttgtcga aaaccaataa aatcatgcaa ctcttgttta ttcataagat
    22501 attacctcac tttcttctat aagcataatg tcattaaaaa tcgatttcaa ttttttcgat
    22561 tcttcacgta atacaggtat tcttatggac tagacagcgc tttgggaaga tggattctct
    22621 gaaaaatata aaggttcact ttatgagtgg ataaaaaaag cagcaaatac ttcgacttct
    22681 ttaatttacc aacattagtg aaaatcgatt catctggaga tttgtaattt agagtccttg
    22741 tcttgattag aggtgtataa agctttttat tagacatttt taaattccat tacaatttgc
    22801 ttataaacta ggtttttaaa ggtgactatg gtaagataat agagatatta ttttgtgatt
    22861 aggagtgtat atatgaataa aaatggagaa tggagtgctg cacgacggat attcattata
    22921 ttaatggatg ttattgtata caatgcagca atatatagta gtttcttact gaagtttcgt
    22981 ggagagatcc cattacgaaa tttagaaact ttccaacact cagcaattat tatttcagtg
    23041 atttttattg cgttgaacat tttgttgggt gcatatgttt tttataatcg aatgatcagt
    23101 gacatcgtgt ttgtcacagt catcggtcag gtattgatga cactagggat catggtagtg
    23161 acttttgcgg gccgctggtt tgcttttcca cgtcttgtta tcttactttc atttgttctc
    23221 ggtacgcttt tcttaagtat ctatcgtatt ctcgtatata aactttattt acgcgtaagt
    23281 cgagataaaa aggtcgtcat tattgggtta gaaaaggatg tcgcaccagc aatccaaaat
    23341 tttggttcaa agaaaaacaa caaacataaa gtcgaagcag tcattcttga taactattat
    23401 gcaaacatca aaaatatgat taaagacatc gatattgtct atcttgcttc tcatatcgaa
    23461 gaaactgaaa aaatcaaaat ctatcaatta gttactaaaa atgaaaaaaa attgtttttg
    23521 aatacaacat ttgaaaactt gacattgatc aatccaaata ttatgaattt cgaagatgaa
    23581 agtattattg aaacatctgg atttagaatc caacctgaat atgaactatt caaacgtttg
    23641 tttgatatca tcgtttcact tgttttatta gttattgctt caccatttat gttattcaca
    23701 gcaattttag tcaaagtgac atcaccggga ccaatcatct ataaacaagt gcggatcaca
    23761 aaaaatcaaa aggaattttc aatctataaa ttccgctcga tgaccgccac agccgaagca
    23821 aaatctggac cagttttagc taagagcaat gatgcacgag taacgcctgt aggtaaattt
    23881 attcgagctg tccgctttga tgaattacca caaatcttca atgtgctgaa aggcgatatg
    23941 tcgatcgtag gaccacgtcc tgaacgtcct ttcttcgtcg atcagttcaa tgcagaaaac
    24001 ccttattact acttacggca taatgttcgt gctggtatca ctgggtatgc acaagtctat
    24061 ggaaaatatg tctctgatta caacagtaaa ttacgttttg atttacttta tatcaaaaaa
    24121 tattcattga tgcttgattt aaagatcttg ctgcaaacca tcaagatcct atttgataaa
    24181 atgtcctctc aaggacttga agaagacgaa aatgtgatct cattggcaga aattgctttt
    24241 ccgaatgaaa aaatctttcg ctagttggga ggcgtaaaaa tgaacaatcc gaaattcagc
    24301 ataatcgtac cagtatacaa tgcagaagca actattggtc gaacgattga tattctaaaa
    24361 gaattggatt atgaagagta cgaagtcgtt ttagtaaatg atggatcaac agatcaaaca
    24421 caggaaatca ttcaagaact gattgaaaat gatgaacgtt ttgaattgat tactacgacc
    24481 aatcaagggc ccggattagc aagaaacgaa ggaataagac agtcaaaagg agaatatctc
    24541 ttattcttcg atgcagatga cacgccagta aaaacgatct tgtcagatta tgatcatttg
    24601 ctagaaaaga gtccaaaagc ggatcttgtt gttagttcgt ttgtttttcg tacaatggac
    24661 gagggaagaa tcgtttccga aaaagaaaac ttagttacag aatgtcacta tctaactcac
    24721 gaagagttta taaaagacat gtatcagtta atgaatgaac agttgatgta tgttgtatgg
    24781 aacaaatgct atcgtagcga tattctgaaa aataaccaaa ttctatttaa aacttataat
    24841 agttgtgagg atcgaatatt taacttacat tattatgaat actgtcatca agtgatcatg
    24901 aacccaaaag tagaatatat ttatgaattt gaaggtggga aggggatcac taatcaatac
    24961 cgacctaaca agttcgaaac atttaaagaa ttctattcat tagcaaatac tgtaacagac
    25021 gatattaata aagacggtat ggcggcgctt cttttaaaag ggacaacttc agttattttt
    25081 tctatttata gtacctctgc aagaacttca aaagagaaga aagacgaagc aaagcagata
    25141 ttgagtgatc cagtgatccg agaagccaag caaattgcta agacggattc ttcagcaaaa
    25201 aaaataacaa agttgcttta caatatgcca gctccactat ttttatctgc tgtaaaagtt
    25261 ggaagcttcg ttgaagtgaa aatgccaggg ttaatggctg ctttgaagcg agtatattag
    25321 ttaatggagg aaaatataat gaaaagaatt ttgcattttc agggacgaat gggtttaggt
    25381 ggagcagagt ctttcatgat gaatttatat cgtaaaattg atcgtacaaa ctatcaattt
    25441 gattttttga tttatgaaga ttatgcagat gttcaagact atcattcaga gattgaaaga
    25501 ttaggaggcc gtatttttgt tgtacctaat cctaagaaaa atatttttaa atatttaata
    25561 gaagtgaata agttactaaa aaaagaatct ttttctatag ttcacaatca ggtttatttt
    25621 ggcgggggaa ttaatttatg gttagccaaa aagaatggaa tcagacagag aattgctcat
    25681 agccatgcaa ctgaagatgg aaaatctcaa aatattgtaa tgaatgtatt gcgtaaattt
    25741 ttaaccaaat tgttgttaca aaatgcaaca gactaccttg ccgttagtca agaagctggt
    25801 gaaagtctgt ttcaaaacca tccctttgag atagttcata atggtattga tttagagctt
    25861 tatagtaaaa attcagaagc taaggttaat aagagaaaag aattggatat ctcaatgagt
    25921 acttttgttg tgggaaacat tggacgatta gagaaacaaa aaaatcaatc ttatttgtta
    25981 gagatttttt tagaaatact aaaaatgaat tctgattctt acttgatttt agtaggtgaa
    26041 gggtcactta gaaataaact gaaagccaaa gcagtagaat tggatataga gaaaagagta
    26101 aaatttttag gagaaagaaa cgatattccc gagttattat ctgtgatgga tgtttttgta
    26161 atgccttctc tttatgaagg tctgccaatg gttggattag aagcacaagc agcaaaatta
    26221 aaattagtct tagcagatac tatttccaaa gatacaaagt taacaaataa tgtggatttt
    26281 gtatcattag atgaaacacc acaagaatgg gcaaaaaaag taataaaaga gccgtatgct
    26341 aataaaataa cacaagaact aaagagttat gatgtttcgt acactactga acaaatggag
    26401 agtatatata gtagagatca ttaaaaatgt tcaagatatt ttaggagtga ttatttttga
    26461 aaatatgtta tttgatattg gcatacaatg atattggcaa cttaaagaga ttggtcaatc
    26521 gattgaacga aaatgcagtt tttattattc atatagataa aaaaactgat atagaaccat
    26581 ttattgaagc atttaaatca tatgataatg ttgaattttt atgtaataaa aaccgtgtta
    26641 aaatttattg gggtggtttt tccattgtac aagcagaaat caatttagta aagagagcat
    26701 tacaaaatga gaaatattta aaatatgtat tattatctgg tgctgattat ccaatcaaag
    26761 ataatgagta tatttataat tattttaaaa agaatagttc agtggagttt attcgtggaa
    26821 tagatctaga tcaaattaaa cataaagaat tttattataa acatatagat gtatatcaaa
    26881 aacatgatta tcctagaatt aataggaata acacaactgc atttaaaatt tttagagcta
    26941 taattaatcg ttgtctgagg atgattaaac ttcccccaaa aattagacac cataaatttg
    27001 atttgtatca tggttctcaa tggtgggctt tgtcgaaaga atgcctaaca gaattaatac
    27061 aaatgtatga acaaaatcaa caagactacc tgaattttaa aataggtatg tttgccccag
    27121 atgaaaaatt ttttcataca ctttttttta attcctcgtt caaaaataaa aatgttattg
    27181 gaggaccaga tttaccactt gaattgaaaa atattgaaga aactacttta caaacttcga
    27241 aattagcaaa tattcatatt attgatcctt ccatgaacaa atggtttgat gaaagggata
    27301 tagatcaaat aaaagaaagt gaaaaattat ttgtaagaaa agttaaatcg gattactctg
    27361 ataaactatt aaatagaatt gataaagaaa ttttgaaagt tggaaatata gatgaataga
    27421 atagtacctg ttttagagaa gagtttatta agtcgagatg cgtttcgagt aataaattta
    27481 atcatttgtc tgctttattt tatgcctagt acttttaatg taactaatat cccgatgaaa
    27541 atagcttttg cttggggtgg aattatagtt ttgtatgagg tttttataaa gaaaaatttt
    27601 tttaaaatgc gtttttcttg gctactgatt ggagcaatga ttagttttat cttaactata
    27661 atcattaaca gagaaaattt tttaattcca tctatttata attttggata tttgctgatt
    27721 actttgatag taatttttcc tgcagacttt tcacaaagtg aagaggaaaa aaagaaaaaa
    27781 atggtgtatt ttaataatgt tttcattatc ataatttttt tagctgcgct aatatctatc
    27841 tatcaattta tttttttgat ttcttatcat gtcccaacag gaacgccagg attacttgca
    27901 agacaaggtt ttattgaaca tcggttattt ggtgtctata caagtccaaa tgttggagct
    27961 atgtttggat atacttctat tattttaagt ttaattagtg tattaatttc aaaaataaca
    28021 aaaacgattc gtgtttttta tatgatgaat tttatcgtac aaatatttta tattacactt
    28081 tcttcgtcta gaggtgccca ggtagtaatt tgttcttttt tagtattatt tcttttgttg
    28141 tttgccaatt caaaatttag aaagagcatt agagaagtac tacctgtaaa aatcaaatgg
    28201 atggtaagca tattattagt tctattggta tatttttctt ttggtactaa ttatgctaag
    28261 gattttttag caacaattcc tgtatcgatt gatagaaaag tagaagttat agagtcaaat
    28321 gaatcagata aaactccact tccagaaaaa gaagtaatat tacagcattc tagtgataac
    28381 tccgaaattt cagctggtcg ttttacgatt tggaaagctg cgcttaaagt tataagacca
    28441 actttgttat ttggttatgg agagaccgat ttctatggga atagcgatgc aaaatttttg
    28501 aaaaaagtag atcttgatac tacagatgtg aatgaactaa aaagagcaca tggaaacatg
    28561 cataatggat ttcttcaagt acttgtatca agtggtataa ttgcttttat atgtatctat
    28621 gctttctatg tgttaaatat ctttagttta ctcaaaacat tttttagaag taaagtgaat
    28681 tatgcgtttc ttggtattgt tttaattttt atactatcta tttttataga tgaaatggtg
    28741 gaggctcatg tacttttcaa taagcgcgat gtcatttcaa ttgttttctg gtattatttg
    28801 ggaagcattt cttacttgta tttaaaaaaa ggagaattaa tatgaagaca gctttcattg
    28861 cttggactcc tttacatttg attaatatat taaatgttta tcaaaatttt taccgagaat
    28921 caaaaggaga tttatttatt tattctgaat ttgaaaacgc tagaagatat agtgagcgta
    28981 taaaagaatt agggctattt aatgatgttg tttttgtgaa tcaccggaaa atcggttctt
    29041 cctttaaacg taaaattaac ttgttaacta accataatca atttttctcg gatgatttat
    29101 ccgtttatga tgaaattttt atacaggggg aaaattattt cacaaaaata cttttctcca
    29161 atgtttacaa aaaaaatcca gatgtaaaac taaattatat agaagatggt ttgggtactt
    29221 atttgaagaa gagtatattt tcaacaagta aaaacgttca aagagttttt aaaatattaa
    29281 ataaaaatag catcttcaaa aaaaaaattg acgattattt tgtctattgt ccggaattgt
    29341 tactttatga tgtaaaaaat ataaaaaaaa ttcccaaaat agatgaaaac agtaaattga
    29401 tgaaaaacat acaatcaatc tttgggatag aagaagtttt tgtcggagat aaatgtatct
    29461 tttttgatca acctttatta tctgatggtt atggcataga tgaaacagat attttcgcta
    29521 aagtaaatag tatattttct ggaaaaaaag aaactttaat taagcttcat cctagagcaa
    29581 ggacaaatcg ttatggtgaa aaaaacatat tgaattccag tttaccgttt gaagtcttgc
    29641 tacttgaaaa tgacttctct tcaacacttt tgattagtcc tatatctaca atttcttttt
    29701 caccatctat gatgtttgaa aagacgatca actctattat gttggctaaa ttaattttaa
    29761 atgaatatac agcattatct gaagataaaa aagaaacatt gacaaatatt gttcttttct
    29821 gtgaacatta taaccgtcta tcagaagaaa aaattttact cccagaaaac tgggcagaat
    29881 taagaaagtt ggtagagtat gggattattt aacacacttt ccaagtcaaa attagttaag
    29941 tccagtttct ggtatactat agggaatttt tttattaagg gaatttcatt cataactatt
    30001 cctatttttg taaatattac tactcaagca gaatatggtt tgattaataa tttcacttca
    30061 tttgtatcaa ttttttcgat tcttgttggg ctaagcctaa attcggcaat taataatgca
    30121 agttttgact ataaagatga cataaatgaa tttatgtcat cggtactttc tctagctaca
    30181 ctttcgttaa ttgtgttctt attaataggg aacatatatt ttttgttttc aaatgctttt
    30241 tttgatatga accaacttgt atttaatttg atgttattac aaagttttgc tagttttgta
    30301 attagttata tccagtctta ttttacgatt aactttaacc attttaaata tttgatttta
    30361 tcttttatat ctactttttt gaatattgca atctctgtag ctttgatgca gacattatat
    30421 tttgatgata aatatgttgg cagagtagtc ggcggaacac tgtcatttgt gttgataggt
    30481 ttagtaattt atttaagaat aatgataaag ggtgctcatt tttttgataa aaaacagtgg
    30541 agatacgctt taaaaatctc tttgccgcta atcccacatt ccttagcaaa tatagtttta
    30601 gcacaattcg atagaattat gattaattct tatttaggtc ctgctgcggg gggaatatat
    30661 tcctacatta gtaacatagg tattattcta agcgtaatat ggatgtctac taataacgcc
    30721 tgggttccat ggttctatgg tgagatgagt aaaaataatg aaaaaaaagt gaagaaagtt
    30781 agtaactatt atttagtagt ctttactttg attacgatga ttgtaatggt agtttcgatt
    30841 gatttagcaa aatttatggc tccgaaagac tattattctg ggttatcttt agtggttccg
    30901 ataaccttag gctatttctt tcagttttta tatagtttac cagttaatgc tgaattttat
    30961 gagaaaaaaa catcgtttat tgcgattggt acagtagcaa gtgctatagt taatatacta
    31021 ttaaacatga ttttcatacc taggttagga ataattgctg ctggatacac aaccgtattt
    31081 acgtattttt tactttttat ttttcattat aatatcgcta aaaaaattac gaataaacaa
    31141 ttatttgaca caaaaaaaat atgtatcata ataatttttg tatcaatttt ttctttgata
    31201 cttcatattt taatcaatca aatgttgatt cgttacgttt tgacatcatt attgataatt
    31261 agtttagtta tatatttttt aaagattaag aatcgaatta tagatgacta taattcatag
    31321 gaggagatat aagtgtttaa aggaaaaaca atattagtaa ctggcggaac tggttccatt
    31381 ggaagtgaaa ttgttcgtca gcttttaaaa tatgaaccaa aagctatcag aatttatagt
    31441 agaggtgaag aaaaacaatt ttatatgcaa caagagctct caaatcacac taatttgaga
    31501 tttttaattg gtgatatcag agactctcaa aggattgatt atgcatgtcg tgatgtggat
    31561 attatttttc atgctgccgc aatgaaacac gttccagcaa gtgaatataa tcctatggaa
    31621 gctgtaaaaa caaatgtgat gggaactcaa aatgtaatag atgcagcgat caaaaataat
    31681 gtaaaacatt ttgtaggtat cagtacagat aaagtagtga gtcctactaa caccatgggt
    31741 gcgacaaagt tattgagtga aaaattaata atagctgcca atcagtataa aggaaaaaca
    31801 gaaacaatat tttcttgtgt aaggtttgga aatgtcatgg ggtcaagtgg atctgttatt
    31861 cctcttttta gtaaacaaat aaaaaacaat aaagatatta ctttgacaga tgttgatatg
    31921 acacgattta tgatgtcaat accggatgct gcaagattag ttctgtctgc tgctatgaat
    31981 tcaaaatttg gagaaacata tgtcttaaaa atgccggcaa tcaatatttt aactttagct
    32041 caatcattaa taaaaatata taatgataca catgatgaaa aatatagagg tgaaataaaa
    32101 gttgtaggta tcaggccagg agaaaaatta tatgaagagc taatgactac agacgaaatt
    32161 gaacgctcat atgaaaatga taaaatgtat atcattccac cacactatca tgctactgac
    32221 gaactgtaca aagattatga aaaaattaaa atcactgcat actcttcaga tgcaacagaa
    32281 ttaatgagtg gacaggaatt tattagaatc gcaaaagaga ataatgtcgt gacttggtaa
    32341 ggagttttat gatgaaatca gaagtatatg taattgcaga aattggtgta aaccataatg
    32401 gaagtctaga tttagcttta gaaagtattg ataaagctaa agaatgtgga gctaacgcgg
    32461 ttaaatttca aacatttaaa acgaataagc tagtttccaa aaaggctcca atggcaaaat
    32521 atcagaagga taatcttaaa gaggacagtt ctcaatttga aatgctaaaa aaattagaat
    32581 tatctcaatc tgattttatt agaataaaag attattgtat acaaaataaa attgattttt
    32641 tgtctactcc ttttgatgaa gaaagtgcag actttctaaa acaaattggt gtacaaggat
    32701 ttaaaattgg ctcaggagat ttaacaaatt taccttttct tagaaaaata gatatgtatg
    32761 ggttgccagt tttattatct acaggtatgg ctgatattca tgaggtcagt gaggctgtag
    32821 attgtttcat agatagtcca gttactattt tacattgtac ttcaaattat ccggctagtt
    32881 ctgaagatat taatttattg gcgattaaca cattaaaaga aatgttcggg atacccgttg
    32941 ggtactccga tcattcattg ggatatgatg ttggtatttg tgctgttgcg atgggtgcta
    33001 aggtaattga gaaacatttt accttggata aggaactacc tggtccagat cataaagctt
    33061 ctttagatcc tcaggaattt gcagattttg taaagcatat tagaaacact gaaatatttt
    33121 taggtgatgg tgttaagcga gcaatgcctt ctgaacttag tacaaaagaa gtatcaagaa
    33181 aaagcctagt ggtcactgag aatttaaatg tgggagatat tcttacagag aaatctctta
    33241 caataaaacg tcctggaaat ggaatagctc ctaagttttt atatcaatat attggcaaaa
    33301 aagttaaaag accaataagt gcagatagtg ttctgcttga ggaagatgtt gaatgaaaaa
    33361 aatacttata gtaagtggaa cacgagctga ttatggaata tataaacctg ttgctgagaa
    33421 tttactacaa gataattggg atgtatcatt tgttgtttct ggaatgcatt tatcccataa
    33481 atatggattt actaaagaat tgatcttagc tgacggattt agaattagtg gagaagttca
    33541 aagtttgttt ttagagaaca ataagggaaa catggctcgg tctgtggcat tagagataaa
    33601 tggtttcaca aatatatttg aacaaactag ccctgatttt gtattattac taggggatag
    33661 aggagaaatg ttggcagctg cgatagcttg tttgtatctt ggaatcaaaa cagcacatat
    33721 tcacggaggc gaagtgtctg gtactgtaga tgaatcaata agacatgcca taacgaaaat
    33781 agcatctgtt cattttgctg ctacggaaaa aagcaaagag cgtttaataa aaatggggga
    33841 agattcttgg agagtttttc ccgtcggagc tcctagaata gatactattt taaataatag
    33901 attacctagt tttagagata taaaagaaaa atatcatcta aaatttgaaa agaaaaaata
    33961 cgttttgcaa gtatttcatc cagttgtaac cgaactagaa aatatagaaa aacaaatttt
    34021 agctttgatc aattcaatgg aacaacaatc tcaaccaatt atttgcattt tacctaatag
    34081 tgatgctggt agcgaaatta tcagaaaaat gtaccagaaa tatttaaaaa cggatattat
    34141 ttatattacg aatttagagc cggaggaata cctgactata ttaaaagagt gcaaatttat
    34201 gatcggaaat tcttcttctg ggataattga agctgcatca ttcaaaatac cagtaataaa
    34261 tttaggaacc agacaaaatg gacgagaaca atctaaaaat attataaatg caaatctaaa
    34321 tgaaaatgaa attgaaactg ctttgaataa aatacaagat cctcagttta taaaaagctt
    34381 gaaaaatgtt aagaacatct acggtgacgg caacagttct agaagaataa caaaaacatt
    34441 gaatcaaata ttgaatgatg gggaagatat taagtggatt caaaaacaaa tagcttatta
    34501 aaatatacta gtgatccata cattattatt ggggctggcg gacacgcaaa agtcattatt
    34561 gaaaccttaa gattagaaaa taagttaata tatggatttt ttgatgataa gcaaaataaa
    34621 atgcaagatc tgaaatatct tgggaaaata aacgaattga atagctgggc ggatagcaaa
    34681 aaaaaaatct ataaatttat tgtagctatt ggtgactgtg tagtaagaaa aaagattata
    34741 aaaaaattga atatgccaag tgagcaatat ggaatagctg ttcatccaag tgctatagtg
    34801 gcaaaagaaa tttcaattgg ttatggaact gttatttttg cgaatgctgt aattaaccca
    34861 gatgctgtaa ttggagagca tgctataata aacacaggta gcattgttga gcatgattgt
    34921 agaattaata actatgttca tttatctcca ggtgtatgct tagcgggtgg agtacatgta
    34981 ggtgtaggaa ctcaaatagg aattggttct caatgtatcc agatgaagaa aattggatct
    35041 tggtgtatga taggcgcagg gagcactatt gttaaggata ttccctcaca ttccttagct
    35101 tatggcaatc cagctaaaat taagaaagaa ggaattaatt ttgaattcta gaattttatt
    35161 atcaagtcct catatgggag gaacagaaga aaaatatgtt gctaaggctt ttaaagataa
    35221 ttggatagcg ccattaggtg aaaatgtgga taaatttgaa gaaagtatta caaaatatac
    35281 tggttctaag ggcggagctt ctgcgttaag ttcaggtaca gctgccatac atcttgcctt
    35341 aagactgctt aatgttggaa aaaacgatat tgtctttgct ccttcattta cttttatagc
    35401 tacagtaaat cctattttat atcaaggggc tgtaccagtg ttcattgact cagaacctaa
    35461 tacatggaat atgagccctg ttgcactaga gagcgcatta gaagaagctg aaagaaacaa
    35521 ccaattacct aaggcaatca tcgtagtgaa tttatatggt caaatggctg attatgaacg
    35581 aattttagct attgcaaacc aatttaatgt tccagtgata gaagatgcag cggaatcgtt
    35641 aggttctact tataagggaa tttcgtcagg cttatttggg acaattggga tctattcatt
    35701 taacggtaat aagatcatca caacctcagg tggaggagct ctagtgtcta gtgataaaaa
    35761 atatgttgag cattcaagat ttttagcaac acaagcaaga gatcaagcac cgtattatca
    35821 acatagcgaa ataggttata attaccgtct aagcaatatt tctgccggta tcggacgtgg
    35881 acaaatggaa gtattgaatg atagagtagc taaacgaaga gaaattttca atcgatataa
    35941 ggaagctttt tctggaattg atagaattga aatgatgcca gaagtggatg gcatggtgcc
    36001 aaatcgttgg ttgtctactt taacgatcaa tgattataat tctattgatc aagtagttaa
    36061 cgtaataaat aaactaaatg aaaaaaacat tgaaacaaga gctttgtgga aaccactaca
    36121 tttgcaacca gtatttcaag gggtaaaaat gtattaccat gataataatc ttagtgtgtc
    36181 agaaaagtta tttaatagcg gcttatgctt accttctgga agtaatatga cagatagtga
    36241 acaagaattt gttattgatg agtttaaaaa aatattcaag taggtgtgat attttatgaa
    36301 cataggaatt attggtttag gttccatggg gaaaagaaga cttagactca ttcaagaaca
    36361 ctttaatgat attttactat gtggtgttga tactaatgag gcgagacgaa aggaagttga
    36421 aaaggaattt ggaataccaa cttataatag tctaacagag gcaaaaaatt tgtttgaaat
    36481 aaattcagtt tttgtttgta catcccctat aacccatgaa tttattataa aagaggcttt
    36541 aaatttagat tgtaatatct ttacggaaat caatttatta aatgaatatt atgatgaaat
    36601 aatcgaagta gctaaaaaga aagatagatt actttatcta tcttctacat ttttgaagag
    36661 aaaagaaatt caatatatta agtctaaagt gacgcataat aaaaaaattt cttatcaata
    36721 ccatgtagga cagtatttac ccgactggca tccttgggaa gattatcgca atttttttgt
    36781 ttcaaacaaa aaaactaatg ggtgtagaga aatattcgct attgaattac cttggattat
    36841 agatacattt gggaaagtta aatcgtttac tgtaatgacc cagaaattat ccaatcttga
    36901 tattgattat tcggacagtt tcactcttat tattgagcat gaaactggta tagttggaac
    36961 tttaagtgta gatgttgttt caagagtagc taaaagaaat ttaactataa ttggtgaaaa
    37021 gattttaata gaatgggaag gtaacccgga ttctctattt tcatggaatg aagaaacttc
    37081 tagtatgaca gatattcaat tgtacgatga ggttatgcat gataataatt attcacatac
    37141 tattattgaa gatgcatatt tagaggagat taaagaattt ttcacgcttt tggaaaagaa
    37201 aatggaaccc caatatactt ttgaaaaaga taagtatatt attaacttaa ttaacgacat
    37261 tgaggtaaat taatgatgaa agtaattttt tttgggttag ggtcaattgg aaagagacat
    37321 ctaaaaaatc taataagcta tggaaaaaag aattctatta attttgatat aacagcttat
    37381 agtagcagtg gaaaaaaaga gtttgaagaa ataacgtata ttcaaaatag agacgatttg
    37441 gatacacatt atgatatagc ttttattaca aatccgactt ttaagcatct ggaaacacta
    37501 aatgtaattg ttgaaaaagt tgattacata tttttagaaa aacctgcttt ttctgagagt
    37561 attgatctta ctcaatataa ttatgattac aaaaatattt atgttgctgc tccactgagg
    37621 tataaaaata tcatggaagt tgttcgtaat agtattcaaa gtaaaaaagt atattctgta
    37681 agagctattt gttctactta tcttcctgat tggagaaaag gtactgatta tagaaataat
    37741 tattctgcct ttaaatctat ggggggagga gtagaattag actgtataca tgaattggat
    37801 tatattataa acctatttgg tttccctaaa tcagtaaaaa aacagtttgg taaatattcg
    37861 aatcttgaaa ttaacagtaa tgatttagca acatatatat tgagatacga tgataaaatt
    37921 atagaaattc atttagatta ttttggaaga gttcctacaa gaaaatttca attgtttact
    37981 ttagatgaat gtatcaatgt tgacttatta aataataaaa taagttttga agaaaacatt
    38041 gttaaagaaa tgcctgaatc tgctaatgat atgtatgaga aggagttgaa atatttcttt
    38101 gaaaacgtag taacaggcaa agaaaactgg aatgatttat atcatgcaaa cgaagtattg
    38161 aaaatagctg aggagaaata aatggaaatt ttatttacta tttgtggtag agctgggtct
    38221 aaggggttta aaaataaaaa tttgaaatat ttggcaggaa agcccctagt ccatttcgct
    38281 ttagcaatga tagatatcta tcaacaaaaa catcctgaac ataattgcac gacttgtttg
    38341 aatacggaca gtaatgagtt agtagaattg acgactaagt taaatccgtc tgtgaaaatt
    38401 gtagaacgta aacctgaatt agctacagat actgtaggga aaattgaagt gatacgtgat
    38461 tcattcttac aactagaaag agaagataat atatttgatt taattataga tttagatttg
    38521 acttcacctt tacgtgaagt ttctaatctt gaagaattaa tagatgaaca tctaaaaaat
    38581 ttagataaag acgtctactt ttcagttgtt tctgcaagac gtaatcccta ttttaatatg
    38641 gtaaaaagaa ttgaaaatga agttactata gttaataaat caagatacac atctaggcaa
    38701 cagacacctg aagtttttga aatgaatgcc tcaatgtatt cttttaaacc tgaatttcta
    38761 aaaaaaagta attatatttt tgatgggcaa tgtgggataa taaaaatgag agattatcta
    38821 attttagata ttgatagtga agaagatttt aaatggttag aatttttgtt tcctaaattt
    38881 ttagaagatt cttcggagct tcaagatatc tataattatt tatatcggag gtaaaaggat
    38941 gagctgttat cttatcaccg gtggggctgg cttcattggt tctaccttag ccaatcattt
    39001 aggagaagaa catgtggtaa tcgtcgtcga tgacttatca atgggaaaag tagaaaatct
    39061 tgatatgacg aaaaatatca cttttattga gggagatgtc gctgagaaat ccttgatgga
    39121 agagatcatg aaagctaata aatttgatta tatctttcat ttagcagcag ttgctagtgt
    39181 ggcagattca gttgcccgac cagtagaaac acatcgtgtg aattttgaaa gtgtattaat
    39241 gattttagaa ttgatccgca agtatcaacc tgatttaaaa cggatcgtgt ttagttcttc
    39301 agcggctgtt tatggggatg aaccgacttt accaaaaaaa gaagagtccg tgattcgccc
    39361 attgacgcct tatgcggttg ataaattcgc tgcagaacaa tatgtgctag attattgtca
    39421 tttatatgat gtacccggta gcgcagttcg ttttttcaat gtctatggtc caaatcaaaa
    39481 tccgaattct ccatacagtg gtgtgatttc tattctcgta gatcgctata agaaacaaat
    39541 cgtaggagaa gcaacttcat ttacattatt tggtgatgga agccagtcta gagactttgt
    39601 ttatatagat gatgtaatcc aagcattact tttagttgcg aatgaggaag ctgcactggg
    39661 gaaacaattc aatgttggaa cgggtaaagc aaccacactt ttggaattga ttcatgcaat
    39721 caatgaaatt ctcggtgtag aattgacact tgaatacaaa gaagagcgtt cgggtgatat
    39781 ccatgactct ctagcagata ttactaagat ccagtcaatt ggctatcaac cgaaatatgg
    39841 tattttaagt ggaatgacta attatttgaa aactgaaatc aattaaaaca tactaagata
    39901 agattagagg gtaaattcag gctctttgtc aataaggact gatgagtttt gtaaaatcaa
    39961 atctgggata gaa
//
LOCUS       DAPBAF010000027        39365 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.027, whole genome shotgun sequence.
ACCESSION   DAPBAF010000027 DAPBAF010000000
VERSION     DAPBAF010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 39365)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39365)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39365
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.027"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            <1..1075
                     /locus_tag="RD451_001579"
     CDS             <1..1075
                     /locus_tag="RD451_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HDT7566845.1"
                     /translation="YKKLLTDNIKKTKDFHFFTGDFNEMFLLYMFKTRYYLFGPFRAN
                     NIDKVFFKLKMNNLNVAMADRERLYNSLQNLTLYSLGDIRDILILVHYFFTGKIEDLF
                     HEPLIEYTENLSKTIEQIKIDNLLSQNYDPEIYLFLYENKILEYVKNGDIRNLENMVF
                     NLSNGIIPSVSGDTIRSEKNYSIIVFEKLAQTSITLGMDIIEAYQSRDALIQENELAV
                     SLPEVLKVRDSGIVYYTKEIGKTKIEHLSPLISSVVQFIGLNIYKRITVKEIANYFSV
                     SETKLRESFKNEMHITIYNYISKRKISTAKIMLKSNHTISEVSLGLGFSDSSHFSRVF
                     KKYAGVSPKQYQLGLVDNFNNIS"
     gene            1092..1526
                     /locus_tag="RD451_001580"
     CDS             1092..1526
                     /locus_tag="RD451_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566846.1"
                     /translation="MRLYHLRSLEELRKLDFNKKFFWEISDLSCFVESERLSNGNNSV
                     LNEYDKVVINKVKSLCEEARESISHINGSNFKQTLFNLIKLDAKISSYLFFLIHDEFM
                     DYQKLDQLIERESWEDYYVGLTFSEKLNNYKLIDYKYLSESN"
     gene            2143..6828
                     /locus_tag="RD451_001581"
     CDS             2143..6828
                     /locus_tag="RD451_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HDT7566847.1"
                     /translation="MVSKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLIGVGLVLGTT
                     ELVKAQDEISPSSPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTKNWEIRLQLDERLAKYVEKIQVDPKKGIGSSRRTFV
                     RINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKSLDEIFKEIGIDN
                     LKTDRLMYRIYLVSHQDDDKIVPGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVS
                     AKYEKPNTQTKDGSGSTGANGAIILDHKLTKNYNFSYSSSAKGTPWYANYKIDERLVP
                     YVAGIQMHMVQADKVTYDVSFESGTKVADLAIERREGHENYGIGSITNNDLTKLIDFA
                     NASPRPVVIRYVLQLTKPLDEILEDMKATAQVEENKPFGEDFIFDSWLSDTNKKLIQN
                     TYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAGT
                     GHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSNKLIAKDELKIQIVSP
                     GFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTSN
                     VTDSTKGIVTVKIGNRTFDVDVEFAVKASQAMENDATYVPITTTPETTVQSGKPTFDK
                     PDVPLAKDAFSISDVYNKYFGNASVDANTGIVTFTPAKGVGESEPITGTIPIKIVYQD
                     GSVGTTDLAVTVSKDIYENPGENIPAGYHKVTFTAGEGTSIESGTTVFAVKDGVSLPE
                     DKLPVLKAKDGYTDAKWPEEATQPITADDTEFVSSATKLDDIIENPGENIPAGYHKVT
                     FTAGEGTSIESGTTVFAVKDGVSLPEDKLPVLKAKDGYTDAKWPEEATQPITADDTEF
                     VSSATKLDDKSDADKYNPEGQKVTTELNKEPDAFEGIKNKEDLPKDTKYTWKEKVDVS
                     AAGNKKGTVVVTYPDGSSDEVEVDVTVTDNRSDADKYEPTVEGEKVEVGGTVDLTDNV
                     TNLPTLPEGTTVTDVTPGGTIDTNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSDA
                     DKYEPTVEGEKVEVGGTVDLTDNVTNLPALPEGTTVTDVTPGGTIDTNTPGNYEGVIE
                     VTYPDGTKDTVKVPVEVTDNRSDADKYEPTVEGEKVEIGGTVDLTDNVTNLPALPEGT
                     TVTDVTPGGTIDTNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSNADKYNPEGQKV
                     TTDLNKEPDASEGIKNKEDLPKGTTYAWKEKVDVSTAGNKKGTIVVTYPDGSSDEVEV
                     DVTVTDTRSDADKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYTWKEKVDVSTA
                     GNKKGTVVVTYPDGSKEEVEVTISVVDKKAPNKPQVDPITEGDQIVTGKTEPNAEVTV
                     TLPDGSQHHGTADKNGNFTVKVPKLEAGTKVIVTATDESGNTSEPTNVVVSSNKKDSG
                     KNGSKGSKTDNQGSNSNQDKNRGKSQSSKVFPKTGESDSNIFTISGGLILLGTLGLLG
                     YKNRKKENE"
     gene            6962..8305
                     /locus_tag="RD451_001582"
     CDS             6962..8305
                     /locus_tag="RD451_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDT7566848.1"
                     /translation="MEKIVIIGSNHSGLAAARFLNLSDSNYEVILIDKKSEISYLECG
                     TSLFIKGEVSNLEDLFYQNRMTLNSEIKKLFLETEVDKIDIQNKKISCVKKDGTRFSQ
                     EYDKVILATGSKQIMLDIPGNNLANIFSIKNFPNAKEIFKALDDSTIKKVGIIGAGYI
                     GVEIAEAIRKRGKEVYLFDVADRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYL
                     GRKKIEKIVTTSGTQYSMDMVVQAIGFLSNSPIGEKELLRDVSGAYLTNEYQQTNIKD
                     IYAIGDCATTFFTSINRSSVDFSISNALRTAYIATQHINNQDFTPSGSQFTNGFSIFN
                     YNFYAAGLNLKTARLLSESIDYIEIEDFIRPAFLRKNSRVKLRISFEKNTKRIVGVQL
                     CSQEDLSGLLSMFSLAIEEQITLDKLKMLDYLFHPSFSQPYNFILKAVTGLNIET"
     gene            8417..9868
                     /locus_tag="RD451_001583"
     CDS             8417..9868
                     /locus_tag="RD451_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HDT7566849.1"
                     /translation="MKKSLKLASAVILMSQLLIATPFHVLASENSTYKIAKERTETTE
                     MSNSDVTAESSELLTTSSSESSTTSNAESSTTSSSESSTTSNAESSTTSSSESSTTSN
                     AESSTTSSSESSTISSTESSTTSSSTSEITSSKVTKPNHIESSKKEAPKTEGQTKTFS
                     TPQQIESTESFQSQPILSGNEEIHFDKNESVENFIMKIGESARKIGQKYDLYASVMIA
                     QAILESASGQSQLAQAPNYNLFGIKGTYNGNFVIMVTNEDLGNGTLYTTQSKFRVYEN
                     YEESFEDYAKLLTKGISGNKDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNEL
                     IKTYDLTNYDKEVKGPQMSKTGYQVPIHNYSITSLFGNRGNEFHRGLDMAATQGEPIH
                     AVKAGKVVKAEFHYSWGNYVVIQHEDGSTALYAHQQQYLVKTGDNVLQGQIIGYVGST
                     GNSTGPHLHLEICKDSSLSQSMLVDPKTLLFGD"
     gene            10217..10849
                     /locus_tag="RD451_001584"
     CDS             10217..10849
                     /locus_tag="RD451_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HDT7566850.1"
                     /translation="MKERYGHLTVVEEITHNGYKKYRCLCDCGNETIVYRSNLLSGRT
                     KSCGCGNYKNRHKYKNLTNKTFGKLVAIKPTKLRSEGTVVWECQCLCGRKKLVSAKRL
                     LKGDVKSCGCLKSKKHHIENKKFGLLTAKYPLDNNCSWKTKWVCHCECGSMCEISYSN
                     LFFGHTQSCGCLKRQETRTCVEGTVIECLTSKLPKNNTSGVKGVYRSKEK"
     gene            11437..12876
                     /locus_tag="RD451_001585"
     CDS             11437..12876
                     /locus_tag="RD451_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDT7566851.1"
                     /translation="MYSYQEDAKVQKNRWWILIAISMFTFMSTLDGSIVNIALPTISD
                     DMGIPMNQAEWVVSVYLMIVCSCLLLFGKIGDSRGKIKVFRIGTLIFVLGSLLCGFNH
                     SLGILLFARVVQAIGASMTMATNAGIITEVFPIHERGRALGAIGAFVSLGSIAGPGLG
                     GLILSQFSWAYIFWINVPVGIVTMLIAEKFLPKDITMSGHTIDGGGFAAIAATIISFF
                     GAIFLGQESGFFHPVPLVLFVISVIAFVSFLKVEKKAASPLISFGIFKNKIFTMSLIT
                     ALLIFSSNFFVNVVIPFYLQNARGLSPSYAGLLMMVFPLMMVVGAPLSGYLTDRVGPE
                     ILVLVGLGLLSVTQVMYMFLSVDSPLWLYIVATAIMGAGNALFQSPNNTMVMSSVTIE
                     NLGLAGSMNSFARNLGMVSGISLSTTVLYQAMSAKMGQQVTNYIANRPDVFLYGMKIT
                     FLGSFVLCFVAFFLTIWRIKKQGGIQKNV"
     gene            13171..13389
                     /locus_tag="RD451_001586"
                     /pseudo
     CDS             13171..13389
                     /locus_tag="RD451_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251366.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            13638..13853
                     /locus_tag="RD451_001587"
     CDS             13638..13853
                     /locus_tag="RD451_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566852.1"
                     /translation="MNAGIADMNLIKKTLNDFTSNSISKGTGINLSTIKKLKSGERSV
                     EKLNLLDAIKITEFAMKNGKAEIEIWR"
     gene            complement(14070..14326)
                     /locus_tag="RD451_001588"
                     /pseudo
     CDS             complement(14070..14326)
                     /locus_tag="RD451_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(14513..15424)
                     /locus_tag="RD451_001589"
     CDS             complement(14513..15424)
                     /locus_tag="RD451_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDT7566853.1"
                     /translation="MKIKIERNQKEKSPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGVESFTEDFAKEYFSWKNNKEAIEKRMSNL
                     EQYLTENGLALIQDMVRADIPTSSEVQSVKILDVEKHSEEFIVSFLVEQHITEGKKTQ
                     SISSAYRVTIFEDENRNHLVTSLPTMIGKPDKAKYEAKQVENDSEIDAKTTEEITDFL
                     ETFFKLYPSASEKELEYYVENGAMRPINIDLKFSELENPVYLQNGKNFLVSTKIKYLD
                     NVSKTTSYFQYKLVLQKNGNWKIVDVK"
     gene            complement(15443..16447)
                     /locus_tag="RD451_001590"
     CDS             complement(15443..16447)
                     /locus_tag="RD451_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HDT7566854.1"
                     /translation="MNLKKVGVISLTFLTISFMGILMCVGLLFGEDSEGNGSSGTSPG
                     GTSVSEEVLKHRAMVEKYAKESDITEYIPILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNYGGGYLDHVGKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENGGWRYNYGNMFYCLLVKQYLTTTQFDDKIVQEIF
                     DEAFKYEGTAYVFGGSSPETGFDCSGLTQWCYAKVDLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTENYWRQHLIGAGRYK
                     "
     gene            complement(16444..18567)
                     /locus_tag="RD451_001591"
     CDS             complement(16444..18567)
                     /locus_tag="RD451_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HDT7566855.1"
                     /translation="MKKKLFRIVGIVFISILTLIVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALTLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRALAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEILSDLTKEN
                     PVSNNKKQSRMNLAGRKIGKVLDTQALVKDKTKQVKDQVRNTPTNLKYNLHKGIEKSK
                     KAPEEFKRGLFQEKADRVDLREKQRQRRNAKMDEKRKILSEATNRQGKRRANIPIDKA
                     AQPQKDMMLKKEAPKRIVRANLNPEIKRKLTSQEIISKGKSQSASKKNSFQQVKQRST
                     LPKQTNQKVQKRMNHRPKSRSGEKK"
     gene            complement(18572..21019)
                     /locus_tag="RD451_001592"
     CDS             complement(18572..21019)
                     /locus_tag="RD451_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDT7566856.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELIPYNYSFLSPEQKYQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLTEVAKQRIDLQTEALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKNLKKSFFSGFQEFVYGVNHHLMGDFVSLSNEEI
                     RRYTKLEKLMESKLARRFKVRRVTPSDLMYLIEHIYGEKGTPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPSRCLIEEKPRYLCMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKDSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEINILNLTSKPKNQGLLDPYVIMEKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSNQRGLLQVINELRKEGSPVAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDRQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDREDESNQKRLRDLENGQCLMQDLYGRVGVVQVHPVFE
                     ELFHAFDTRPPVQERME"
     gene            complement(21006..21395)
                     /locus_tag="RD451_001593"
     CDS             complement(21006..21395)
                     /locus_tag="RD451_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDT7566857.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEGAFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            complement(21455..21958)
                     /locus_tag="RD451_001594"
     CDS             complement(21455..21958)
                     /locus_tag="RD451_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HDT7566858.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELEGTPVGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCDDMSDVAYFLIVEAGDFGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFEYPY"
     gene            complement(21971..22195)
                     /locus_tag="RD451_001595"
     CDS             complement(21971..22195)
                     /locus_tag="RD451_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566859.1"
                     /translation="MSGTYLSIYQWFLTNAQSLVLLAIVVIGLFLGFKREFSKLIGFL
                     VIALIAVGLVFNASGVKDVLLSLFNRIVGA"
     gene            complement(22299..24209)
                     /gene="ltrA"
                     /locus_tag="RD451_001596"
     CDS             complement(22299..24209)
                     /gene="ltrA"
                     /locus_tag="RD451_001596"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HDT7566860.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
     gene            complement(24954..25091)
                     /locus_tag="RD451_001597"
     CDS             complement(24954..25091)
                     /locus_tag="RD451_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HDT7566861.1"
                     /translation="MKRGIVMGIVKDIFLVFGGSMLGVTVMCLMNASAAADRAMEKKG
                     K"
     gene            complement(25088..26272)
                     /locus_tag="RD451_001598"
     CDS             complement(25088..26272)
                     /locus_tag="RD451_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HDT7566862.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATACGLSRPYLNQIENGGV
                     TASIKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDARKIIQEILHLKFEYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPELTKKCQKEECISLFRTFKSYRSGELLKADEKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAFHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNRKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNRTTYIQDMVQNARLSDRHKKILEQQSMAIENL
                     II"
     gene            complement(26531..26821)
                     /locus_tag="RD451_001599"
     CDS             complement(26531..26821)
                     /locus_tag="RD451_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566863.1"
                     /translation="MVYDELIGEIYWVIGKIQSDPELEEQLRRLKFDIRKNGVKVAGD
                     PYLMNEETDARIEINQVIAEFERIADQAKEPDIRQYLLEMKAELEVNGITDE"
     gene            complement(26811..27953)
                     /gene="dcm"
                     /locus_tag="RD451_001600"
                     /pseudo
     CDS             complement(26811..27953)
                     /gene="dcm"
                     /locus_tag="RD451_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613853.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
     gene            complement(28029..28193)
                     /locus_tag="RD451_001601"
     CDS             complement(28029..28193)
                     /locus_tag="RD451_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566864.1"
                     /translation="MTEKEQVTKIVKKYNKSIADLSENATAKEFKTVIKYVADQANEK
                     QRKLVGLNKK"
     gene            complement(28186..28860)
                     /locus_tag="RD451_001602"
     CDS             complement(28186..28860)
                     /locus_tag="RD451_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HDT7566865.1"
                     /translation="MESNDSYLEYAKANKDKFISYIIKGKSPEVGRDAVFMAGSPGAG
                     KSEVAIGLAENYDNHVIIDADYFRTQFPDYNGKNSSLFQKASSWLVEQAFRYVLDHGY
                     SFILDATFAILSAEKNISRALKKHFRVTIFYVYQDPKIAWKFTQEREIAEGRHVPKKA
                     FINAFFKSRENIAKVKSKHPDVLLHIIIKDYTNNISEVHYATDNLELFLPLGYSRKDL
                     EVQLHD"
     gene            complement(28938..30278)
                     /locus_tag="RD451_001603"
     CDS             complement(28938..30278)
                     /locus_tag="RD451_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HDT7566866.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQEFRQFDI
                     SKLSLSTIEIVWSIKDLVCLLGSLAFSGAMILLYIHFFLDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTRETISYFPKICYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIDEVVAENGTLRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFILDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMARSKAMKEMSNYKTGENYAYLGLPPNFLIFDEYVAYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSELGYS
                     MMFGEVEKNFFMKHIKGRGYVDTGGSVISEFYTPLVPKGYDFLDSISKLEKMND"
     gene            complement(30361..30696)
                     /locus_tag="RD451_001604"
     CDS             complement(30361..30696)
                     /locus_tag="RD451_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HDT7566867.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLVKALTSDEKMFLIIHQGLL
                     GENSDSEEDSDVLDWLGEEESFFIVVEVNENLCRQAESILEEIGVEMPDAIEGFLNQL
                     VETKQLPSS"
     gene            complement(30706..31080)
                     /locus_tag="RD451_001605"
     CDS             complement(30706..31080)
                     /locus_tag="RD451_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HDT7566868.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTIGNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPNQGNPTNQNERKK"
     gene            complement(31093..31407)
                     /locus_tag="RD451_001606"
     CDS             complement(31093..31407)
                     /locus_tag="RD451_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HDT7566869.1"
                     /translation="MELKFVVPDMAETFGKLSYAGEGEIITEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            complement(31520..34747)
                     /gene="fss3"
                     /locus_tag="RD451_001607"
     CDS             complement(31520..34747)
                     /gene="fss3"
                     /locus_tag="RD451_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HDT7566870.1"
                     /translation="MYKKQKKKLCVLTILSLAVQAIVGAIAPTITFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGFKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIDDYQKKPTFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENAANIDYRVN
                     GNQLIITPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKESGDVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTTTIKAGETIYVTSKNAREKGQIILDKSGVETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDENGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELKYANQTVAPVTSNVKGQNQEVTGETTLTKEDKDTGDKAQGKAVFEGAEYTL
                     FTAKDGKAVKWSEAFKPELAKGTKGSDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYSLDETKYPVSIKKVDDSEKNAVITRNVTAKEQVIRFGFDFFKFAGSAAGTTETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDFVKSEYVFTITEQDQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLATWKDGNKELTSLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     DATKAAQEKDEKAKPVVIAETSATLANKEKTGTWKIQHKLTAEQVLNKTIVLFNYVYE
                     NKEAFEAGDKPVAKDVSLNNQAQTVSCTVEHHVSIQTKAHLENGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDGTNKEIWKSGKIDYEVNDKEFTKTVLAKKVDT
                     GKYPEGTKFTFAEINYDKDGNINGKHNEDLKEKSQTLTPKEVPTILSTPKQPETPTVP
                     SGSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            35535..35858
                     /locus_tag="RD451_001608"
     CDS             35535..35858
                     /locus_tag="RD451_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566871.1"
                     /translation="MFSFAFYMVWLQREVPTHIQGRLMSTITTITMVASPLGLALFGA
                     LFDWKTTQPRLRDSLIFLGGSLAIVILITGLVKLLKLDLKEAKIFSEEEYRETTLVEK
                     KESGN"
     gene            36022..36939
                     /locus_tag="RD451_001609"
     CDS             36022..36939
                     /locus_tag="RD451_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDT7566872.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            36932..37714
                     /locus_tag="RD451_001610"
     CDS             36932..37714
                     /locus_tag="RD451_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7566873.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMLAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LTLGTLSVPVALTFITRSTSVSLLLSFLYIMGTAFIPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            37715..38395
                     /locus_tag="RD451_001611"
     CDS             37715..38395
                     /locus_tag="RD451_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7566874.1"
                     /translation="MVLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            38388..39284
                     /locus_tag="RD451_001612"
     CDS             38388..39284
                     /locus_tag="RD451_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDT7566875.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWLDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDPFIRLTVANPIKPGTQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
BASE COUNT        12293 a         7476 c         7203 g        12393 t
ORIGIN      
        1 ttataaaaag ttactaactg ataatattaa aaaaactaaa gatttccatt tctttactgg
       61 tgattttaat gagatgtttc ttctatacat gtttaaaacc agatattact tatttggtcc
      121 atttagagca aataatattg ataaagtttt ttttaaacta aaaatgaaca atttgaatgt
      181 tgcaatggct gatagagaac gactctataa ttcattgcaa aatttgactt tgtattcttt
      241 aggagacatt cgagatattc tgattttagt tcattatttt tttactggaa aaatagaaga
      301 tctattccat gaaccgttaa ttgaatatac agaaaatcta agtaaaacta tcgagcaaat
      361 caaaatagat aatctgttat cacaaaatta cgatccagaa atatatctgt ttctttatga
      421 aaataaaata ctggaatatg ttaaaaatgg agatattcga aatttagaaa acatggtttt
      481 taatctgagt aatggaataa ttccaagtgt tagtggagat acgattcggt ctgaaaaaaa
      541 ttattctatc attgtttttg aaaagttagc acaaacgtct ataacattag gaatggatat
      601 aatagaagcg tatcaaagta gagatgcttt gatacaagaa aacgaattag ctgtatcgtt
      661 acctgaggtc ttaaaagtga gggattctgg gattgtttat tatactaagg aaatcggaaa
      721 aactaagata gagcatcttt ctcccttaat ttcttctgtc gttcaattca tcggcttaaa
      781 tatctataaa agaattactg taaaggaaat agctaattat ttttctgtaa gtgaaactaa
      841 attaagagaa agctttaaga atgaaatgca tattacgatt tataattata tctctaagcg
      901 aaaaatttct acggctaaaa taatgttgaa atcaaaccat actatcagtg aagtttcttt
      961 aggtttagga ttttcagatt cttcacactt ttcgagagta ttcaaaaagt acgcaggtgt
     1021 atctcctaag caatatcaat taggtttagt ggacaatttc aacaacatta gctgagaggt
     1081 tttattttat tatgagacta tatcatttac gtagtttgga ggagttgagg aaattggatt
     1141 ttaacaaaaa atttttttgg gaaatttctg atttgagttg tttcgtagaa tctgagcgtc
     1201 taagtaatgg taataatagt gtgttaaatg aatatgacaa agtagtaatt aataaagtaa
     1261 aaagtttatg tgaagaagct agagaatcta tcagtcatat taatggtagc aattttaaac
     1321 aaacattatt taatctgatt aagctagatg ctaaaatatc aagttattta ttctttttga
     1381 tacatgatga atttatggat tatcaaaaat tggatcagtt aattgaaaga gaaagctggg
     1441 aagattatta cgtgggtcta actttttcag aaaagttaaa caactacaag ttaatagatt
     1501 ataagtattt gagtgaaagc aattaattat tcatgtagag tactagacac tttaaatatg
     1561 gacaattcaa ttataaagaa aaagaatcaa taatttaatg aggctgtgac aaatgtcatt
     1621 ttttgtttcg ctaaaaacga gtgaaaaaat gttgataact ccaatcattc gtttaagatt
     1681 ctaggaatca ttcagaaatg ctgtgaaacc gatactttat aattataaag aaggtgattt
     1741 caaattccga agaaggaatt tgaagtcacc tttttactta tgtcacagtc tcattcagta
     1801 atgcgggata aggctcctta ttccgttatt tgaatactct gaagtttaat ctaagaaagg
     1861 gtaatatttt gaaaacatgc ttcatcgcat agaaatgaac ttaatttcag aaagaataca
     1921 tacatatctt tttatatgtt ttcagctgct gaatggttaa aaagcacaaa tatccgaaaa
     1981 aaacatgaag aaatgtactt tttttgttgt aatgttcatg aaattctcta agtaaattag
     2041 ttaacataag gttagtaaga ttcctattct gtgaataata cgtatcagat ttatctttta
     2101 ttcttactag gaaagtaatt attaagggag ttgatttgaa taatggttag caagaataat
     2161 aagagagtat ttctagaaaa aacaaagaaa cgagtattga agtacagtat caaaaaatta
     2221 agtgttgggg ttgcatctgt tttgattggt gttggtcttg tcttgggaac aactgaacta
     2281 gttaaagcac aagatgaaat ttctccaagc agcccacttg aaacagcgat aagctccgta
     2341 caagtaggtg acaaagtagc ttcggggaat acttttcagg agaatcctgg ttatacgaaa
     2401 aattataact tttcggattt acaatttagt cctcaagaac taactggaga cacactaaaa
     2461 ggcaatacaa ttggatttga agtttacgga aaacataata ttgcagcatc aactaaaaac
     2521 tgggaaatcc gtcttcaatt agatgaacga ttagctaaat atgtagaaaa aattcaggtc
     2581 gatccaaaga aaggaattgg atcttctaga cggacctttg taagaattaa tgattcgctg
     2641 ggtagaccta caaatatttg gaaggtcaat tatattcgtg caagtgatgg attatttgct
     2701 ggggcagaaa caaccgatac gcaaaccgct cctaatgggg taattacgtt tgaaaagagc
     2761 ctagatgaaa tttttaaaga gataggcata gacaatctca agaccgatcg tttaatgtat
     2821 cgaatctact tggtaagtca tcaagacgat gataaaattg taccgggtat tgatagtacg
     2881 ggctactttt taacagattc agatgatttc tataatagct tagatgtatc tgaaaataat
     2941 cctgaccagt ttaaacatgg atcagtaagt gcaaaatatg agaaacctaa tactcaaaca
     3001 aaagatggtt caggatccac aggtgctaat ggagctataa tcttagatca taagttaacg
     3061 aaaaattata atttctcata ttcatcttcc gcaaagggca cgccttggta tgctaattac
     3121 aaaattgatg aacgattagt tccatatgta gcgggtatac agatgcacat ggttcaggct
     3181 gacaaagtaa catatgatgt ttcgtttgaa tccggaacaa aagtagctga tttagcaatc
     3241 gagcgacggg aaggtcatga aaattatggc ataggttcaa taactaataa tgatttaact
     3301 aaacttatcg attttgctaa tgcaagtcca cgtccagtcg ttattcgata tgttttacaa
     3361 ttgactaagc cattagatga aatcttagaa gatatgaaag caacagcaca agttgaagaa
     3421 aataaaccat ttggtgaaga tttcatcttt gattcttggt tgtcggatac gaataaaaaa
     3481 ttaatccaga acacttatgg aacaggttat tattatttgc aagatattga tggtgatgga
     3541 aaccctgacg ataaagaaga gagcggagac acgaatccat atatcgggaa acctgaatta
     3601 gaagaagtat atgatgttga cacaacagtt aaggggaaag tattcatcca cgagttagcg
     3661 ggaacaggtc acaaagccca acttgttgat aaagaaggta ctgtattagc agaaaaaact
     3721 atcgctccaa atgaaaaaga tggggctcca atttcagata ctgtagaatt tgaatttacg
     3781 ggtgtagatt caaataaatt aatcgcgaaa gatgaattaa aaatccaaat cgtttctcca
     3841 ggttttgata aaccagaaga aggttcaacc gttattaagg aatcaccaaa agcggttgat
     3901 aaacaaaccg tggtagttgg atttaaacca gatgctaaag aatcaattcg gaataataaa
     3961 aacttacctg aagatgcaga gtattcatgg aaaacagagc ctgatacttc taacgttact
     4021 gatagtacga aaggtattgt aactgttaag atcggaaatc gaactttcga cgtggatgta
     4081 gagtttgctg taaaagcttc tcaagctatg gaaaatgatg caacatacgt acctataaca
     4141 acaactccag aaacgacagt tcaaagtgga aaacctacat ttgataaacc agatgttcct
     4201 ttagctaaag atgccttttc aatttcagat gtctataata agtacttcgg taatgcaagt
     4261 gttgatgcaa acactggtat tgttacattc actccagcta aaggtgtagg agaatcggag
     4321 ccgattactg gaacaattcc tattaaaatt gtttaccaag atggttctgt aggcacgacc
     4381 gatttagcag taactgtaag taaagatatt tatgaaaatc caggagaaaa cattcctgca
     4441 ggctaccaca aagtaacctt caccgcaggg gaaggaacaa gtattgaaag tggaacaaca
     4501 gtctttgcag tgaaagacgg cgtaagcttg ccagaagata aacttccagt gttgaaagca
     4561 aaagatggtt atacagatgc gaaatggcca gaagaagcaa ctcaaccaat tacagcagat
     4621 gatacagaat ttgtatcaag tgcaacaaaa ctggatgata tcattgaaaa tccaggagaa
     4681 aacattcctg caggctacca caaagtaacc ttcaccgcag gagaaggaac aagtattgaa
     4741 agtggaacaa cagtctttgc agtgaaagac ggcgtaagct taccagaaga taaacttcca
     4801 gtgttgaaag caaaagatgg ttatacagat gcgaaatggc cagaggaagc aactcaacca
     4861 attacagcag atgatacaga atttgtatca agtgcaacaa aactggatga taaatctgac
     4921 gctgacaaat ataatcctga aggtcaaaaa gtgactacag aattgaataa ggaaccagac
     4981 gcatttgagg gaattaagaa caaagaagat ttaccaaaag atactaagta tacttggaaa
     5041 gaaaaagtag atgttagcgc agctggaaat aaaaaaggga ctgttgtagt gacatatcca
     5101 gatggatcat ctgatgaagt tgaagtagat gttacagtga cagacaatcg ttctgacgcc
     5161 gataaatatg agccaacagt agaaggcgaa aaagtagaag ttggaggcac agtagatcta
     5221 acagataatg taaccaacct accaacatta ccagaaggaa caacagtaac agatgtcact
     5281 cctggtggta cgattgatac caacacacca ggtaattacg aaggggttat cgaagtaacg
     5341 tatccagatg gtacgaaaga tacagtgaaa gttccagtag aagtgacaga caatcgttcc
     5401 gatgccgata aatatgaacc aacagtagaa ggcgaaaaag tagaagttgg gggcacagta
     5461 gatctaacag ataatgttac taacttgcca gcgttaccag aaggaacaac agtaacagat
     5521 gttactcccg gcggtacaat tgataccaac acaccaggta attacgaagg tgtcattgaa
     5581 gtaacgtatc cagacggtac gaaagatacg gtgaaagttc cagtagaagt gacagacaat
     5641 cgttctgacg ccgataaata tgaaccaaca gtagaaggcg aaaaagtaga aattggaggc
     5701 acagtagatt taacagataa tgttactaac ttgccagcgt taccagaagg aacaacagta
     5761 acagatgtta ctcccggcgg tacaattgat accaacacac caggcaatta tgaaggtgtc
     5821 attgaagtaa cgtatccaga cggtacgaaa gatacggtga aagttccagt agaagtgaca
     5881 gacaatcgtt ctaatgcaga taaatacaat cctgaaggac aaaaagtgac tacagactta
     5941 aataaagagc cagatgcatc tgagggaatt aagaacaaag aagatttacc aaaaggaact
     6001 acttatgctt ggaaagagaa agtagatgtt agcacagctg gaaataaaaa aggtactatt
     6061 gtagtgacat atccagatgg atcatctgat gaagttgaag tagacgttac agtgacagat
     6121 actcgttccg atgcagataa atataatcct gaaggacaaa aagtgactac agacttaaat
     6181 aaagagccag atgcatctga gggaattaag aacaaagaag atctaccaaa aggaactact
     6241 tatacttgga aagaaaaagt agatgttagt acagctggaa acaaaaaagg tactgtagta
     6301 gtaacatatc cagatggatc taaagaagaa gtagaagtta ctatttctgt agtagataaa
     6361 aaagcaccga ataaacctca agttgatcct attacagagg gtgaccaaat tgttactggt
     6421 aaaactgaac caaatgcaga ggtgacagtt acattaccag acggaagtca acaccatggg
     6481 acagctgata aaaatggtaa ttttacagtt aaagttccta aattagaggc agggacaaaa
     6541 gtgatagtaa ctgcaactga tgaatctggt aatactagtg aacctactaa tgtagttgtt
     6601 tcttccaaca aaaaagacag tggaaaaaac ggtagtaaag gtagtaagac tgacaatcaa
     6661 ggtagcaaca gcaatcaaga caaaaataga ggcaaaagcc agtcctcaaa agtttttcct
     6721 aagacgggag agagtgacag taatatcttt actattagcg gtggtttaat actgttagga
     6781 acgttaggat tattagggta taaaaatcga aaaaaagaga atgaatagaa aatcaatttc
     6841 ttaagtcttc tctgagaaga ggaagaatct ttttcttcct ctttttgctt ttttatgatg
     6901 ggaaataagt gttagttaaa gatgaatata ctttttatag aaaggaaaag aatgtaatta
     6961 agtggaaaaa atagtaatta ttggttcaaa ccattcaggg ctagccgcag ctcgatttct
     7021 aaacttaagc gattcaaatt atgaagttat tctaatcgat aaaaaatcag aaattagtta
     7081 cttggaatgt gggacatcgt tatttataaa aggagaagta agtaatttag aagatctttt
     7141 ttatcaaaat agaatgacac taaattctga gataaaaaag ttatttctag agacagaagt
     7201 tgacaaaatt gatattcaaa ataaaaagat tagttgtgta aaaaaagatg gtacaagatt
     7261 ctctcaagaa tatgacaaag ttatattagc tacaggttca aagcaaatta tgctagatat
     7321 accggggaat aatttagcta atattttttc gataaagaat tttccaaatg caaaagagat
     7381 ttttaaagct ttggatgata gtactattaa aaaagtagga attattggag caggatatat
     7441 tggagttgaa attgctgaag ccataagaaa aagagggaaa gaagtatatc ttttcgatgt
     7501 tgcagataga gtgttgtcga cttattacga ccgtagtttt tcagataaag ttgaagaaat
     7561 actatcaaaa aatggaatac atctttgtct atcagaaagt cctaaaaaat atttaggaag
     7621 aaaaaagatt gaaaaaatag tcactacaag tggtacccaa tactctatgg atatggtcgt
     7681 acaagctata ggatttctat ctaatagtcc aattggggaa aaggaactct tgagagatgt
     7741 tagtggagca tatctaacta atgaatacca gcaaacaaat ataaaagata tatatgctat
     7801 tggggattgt gctacaactt tttttacgtc cattaataga agtagtgttg atttttctat
     7861 ttctaatgct ctaagaacag cttatattgc aactcaacat attaacaatc aagattttac
     7921 accttctggt tcccaattta caaatggctt ttctatattt aattacaatt tttacgcagc
     7981 aggtttgaat ttaaaaacag cacgattatt aagtgagtct atagattata tagaaataga
     8041 agatttcatt agacctgctt ttttgagaaa aaatagtcgt gtaaaattaa gaattagctt
     8101 tgaaaaaaat acaaagagaa tagtaggtgt acaactttgt agtcaagaag atttatctgg
     8161 actattatca atgttttctc ttgctataga agaacaaatt acattagaca aattgaaaat
     8221 gttagattat ttatttcatc ctagttttag ccaaccctat aattttattt taaaggcagt
     8281 aacaggatta aacattgaaa cataatcgtt actaaatgaa atcaagaaat atactgtatt
     8341 actcaattca ttgaaaatat ttatcataat ttttaataga aaacactatt aaagagaaaa
     8401 aagagaggta aatcaaatga aaaaatcttt aaaacttgca tcagcagtta tattaatgtc
     8461 ccaactcctt atagcaacac ctttccatgt gttggcaagc gaaaattcaa catacaaaat
     8521 tgcaaaagaa agaaccgaga cgactgaaat gagtaattcc gatgtaacag cagagagtag
     8581 tgaacttttg acaacttcat caagtgaaag tagtacgact tcaaatgccg agtcttcaac
     8641 aacttcatca agtgaaagta gtacgacttc aaatgccgag tcttcaacaa cttcatcaag
     8701 tgaaagtagt acgacttcaa atgccgagtc ttcaacaact tcgtcaagtg aaagtagtac
     8761 gatttcaagt accgaatctt caacaacttc aagtagtaca agtgaaataa cttcttcgaa
     8821 agtgacaaaa ccaaaccata tagaatcttc aaaaaaggaa gcgccaaaaa cggaaggaca
     8881 aacaaaaact ttttcgacac cacagcaaat agaatcaaca gaatctttcc aatcacaacc
     8941 aatactatct ggtaatgaag aaattcattt tgacaaaaat gaatctgtag aaaattttat
     9001 tatgaaaatt ggtgagtctg cgagaaaaat tggtcagaaa tatgatttat atgcttctgt
     9061 tatgattgca caagcgatct tagaatctgc cagtggtcaa agccagttag ctcaggcacc
     9121 gaattacaat ttatttggga taaaaggaac ttataatgga aactttgtca ttatggtaac
     9181 aaacgaagat ttgggtaatg gaacgcttta tacgacccaa tcaaaattta gagtgtatga
     9241 aaactatgag gaaagctttg aagattatgc caaattatta actaagggaa ttagtggaaa
     9301 taaagatttt tatgcaggag cattaaaagc taatagtaaa acatatcgag aagcaactaa
     9361 attccttaca ggacggtatg caacagatac acaatactat ttgaagctaa atgaattaat
     9421 taaaacctac gatttaacca actatgataa agaagttaaa ggtccacaaa tgagtaagac
     9481 tggataccaa gtgcctattc ataattattc aataaccagt ttgtttggaa atcgtggaaa
     9541 tgaatttcac cgaggacttg atatggcagc tacacagggt gagccgattc atgcagttaa
     9601 agctggtaag gttgttaaag cagagtttca ctactcttgg ggaaattacg tggtgataca
     9661 acacgaagat ggatcaaccg cgttatatgc tcaccagcaa caatacctag taaaaactgg
     9721 agataatgtt ttgcaaggac aaataattgg ctatgtagga agtactggga atagtactgg
     9781 cccacacctt catttggaaa tttgcaaaga tagtagtctt tctcagagca tgttagttga
     9841 tccgaaaacc ttattattcg gagactaaaa aaggtaatca atctgacaaa gtaacaagaa
     9901 aatggttgga ttcttagacc tttgatcagg atattgagac tggaattgat atctcgatta
     9961 cgatgggttt gacaaataaa acaagtccat tatcgaatat cgagtgtatt attgccgtct
    10021 ttatgctcat attttgagca ggtttcacta gatgaaaaca atttatctat cttgaggatt
    10081 tcgtgtacgt atcgttcagt cttgtattgt aaattagtca taaaatcaga ctaagaaaaa
    10141 ttggaaatat ttttttctga tttattaaaa gttaattgaa attatatggt acttctttct
    10201 tgggagggta ggtgcagtga aggaaagata tggtcacctt actgttgttg aggagattac
    10261 tcataatgga tataaaaaat atcgttgcct atgtgactgt gggaatgaaa cgattgtata
    10321 tcgatcaaac ttactatcag gtagaaccaa aagttgtgga tgtggaaatt ataaaaatag
    10381 gcataaatat aaaaatttga caaataaaac ttttggtaag ttagttgcaa tcaagccaac
    10441 taaactgcga agtgaaggaa ctgttgtttg ggaatgtcaa tgtctgtgtg ggagaaaaaa
    10501 gttagtatcg gcaaagcgac ttctaaaagg tgatgtaaaa agctgtggat gtttgaaatc
    10561 aaaaaagcat cacattgaaa ataaaaaatt cggattactt actgcaaagt atcctttgga
    10621 caataactgt tcatggaaaa caaaatgggt ttgtcattgt gagtgtggca gtatgtgtga
    10681 gataagttat agtaacttat tttttggaca tactcaaagt tgtggatgtt taaaaaggca
    10741 agaaacaagg acatgtgttg aagggacagt aatagagtgt ctaacgtcaa aattaccgaa
    10801 aaataataca agtggtgtta agggagttta tcgttctaaa gagaaataga ttgcgtatat
    10861 aactttaaaa aaaaagaggt actatttagg atcgtatgat tctattaaga gtgcagctca
    10921 agctagaaaa gatgctgaaa ataaattgtt tcaacctttg attgacaaat atcgaggtaa
    10981 tcattaatta ttgtggataa taattaacag tgatatataa acatctataa tatattattc
    11041 atactattga tatttagtat aatcctatgg aattgaatat catagcaatg tatttgaaaa
    11101 gcaaattgga aaacaaatag gtgcaacacc ataaatatga aaaaattggg aaaaagtaga
    11161 atggaaattt gcttacgtct cacgagatag ctcacactat taatctgaag aacaatgaag
    11221 tcgactttta gaaattgcta gaagaaagta aagcgaatta tcactagtta ctatagagta
    11281 agttcaaata aagcatctcc aacttacatg gttacatgag gatatcaaat cgaaattact
    11341 caagcttcct atggctagag tcgcgagaag ttgttgggca gtagacatag gttatattgt
    11401 tcttagctac acgatcatta gaaaggaaat cctattatgt atagttatca agaagatgca
    11461 aaagtccaaa aaaatcgctg gtggattttg attgctatat ctatgtttac cttcatgtcc
    11521 acattggatg gcagtattgt caatattgca ctacctacca tctcagatga tatgggcata
    11581 ccaatgaatc aagcggaatg ggtagtgtcc gtttatctga tgattgtctg ttcttgtttg
    11641 ttgctgtttg gtaaaattgg cgatagccgt gggaaaatca aagtatttcg gattggtacg
    11701 ctgatctttg tcttgggatc gctgttgtgt gggttcaatc attcgctagg tattttattg
    11761 ttcgcacggg tggtacaagc cattggtgct agtatgacta tggctacaaa tgccggaatc
    11821 atcacggaag tctttcccat acatgaacgt ggtcgggcat tgggagcaat aggtgcgttt
    11881 gtttcattag gctcgattgc tggaccaggt cttggcggct tgattttgtc ccaattttct
    11941 tgggcgtaca ttttttggat caatgtaccg gtgggaatcg taacgatgtt gattgctgaa
    12001 aaattcttac caaaagatat caccatgagc ggccatacaa tcgatggagg gggctttgct
    12061 gccattgcgg ctacgattat cagctttttt ggagcaatct ttttggggca agaaagtggc
    12121 tttttccatc cagtccccct tgtactgttc gtaatttcag tgattgcctt tgtcagcttt
    12181 ttaaaagttg aaaagaaagc agcctctcca ttgatttctt tcggtatttt taagaacaag
    12241 atttttacca tgagcttgat tacagccttg ttgatttttt cttccaactt ctttgtcaat
    12301 gtagtgattc ctttttatct gcaaaatgct cgcgggttga gtcctagcta tgctgggctg
    12361 ttgatgatgg tctttccttt gatgatggtc gtcggggcgc ctttaagcgg ctacctgacc
    12421 gaccgggttg gcccggagat tttggtatta gtaggcttgg gcttattgtc ggtaacccag
    12481 gtcatgtata tgtttttgtc agtggactct cctttgtggc tatacattgt cgctactgcc
    12541 atcatgggtg ccggcaatgc cttgttccag tcccccaata atacgatggt tatgagctcg
    12601 gtcactatcg aaaacttggg actggcaggc tcgatgaatt cctttgcccg aaatttgggg
    12661 atggtcagcg ggatttcgct ttctacgacg gtcttatatc aagcgatgtc tgctaagatg
    12721 ggccagcaag taactaacta tatcgcaaat cggccggatg tctttttata tggaatgaag
    12781 attacctttt taggcagctt tgttttgtgt tttgttgcct ttttcctgac tatctggcgt
    12841 atcaaaaaac aaggaggtat tcagaaaaat gtctgaaaaa accactgttg aagaattttt
    12901 ggaggcctgc gtatgggtga gtgggatttc catggatgat ggaagatgaa gtgaacttct
    12961 aaaagccgaa aaactcaagt attatcttca aaatactagt gctcaatgag atgcttgatt
    13021 tgatcacaag aagactgcga aagccgctgg caaccgcaag ctaggtatcc caccgatgga
    13081 ctacgtttta gaggctactg gttatgaata cggagccaac gctctcatct gcataagaat
    13141 acatcaccca gattatgtaa agattttcga tacttctgtc aaaaaatcat taagatagat
    13201 aaatgatttc cgtctagtca aattggttca gaatgtagac acacagatgg taagaagtca
    13261 ctcacaattc gagaatggac ttgtcctatt tgccgtatac atcataatcg aaacgtcaac
    13321 gatagtatca atattttgac caagggctat gaatacaagc attgccttag aaaacatcaa
    13381 gaaccttagg aacaacgggg atagcttggt taataagaga taccgctgtt taggcttgca
    13441 agtatactct tttatcaaga attccgtggc tttagtcatg agaggcttaa tactatgaaa
    13501 attttcttta gcatttttga tttaggttcc ttttctaatt ataataagat gaccactaca
    13561 gtaacctact gaaatatata aacagccact gtagtaccat tttcaaagta gtctatgaga
    13621 ggagaatctt cattcttatg aacgctggaa ttgcggatat gaatttaata aaaaaaaccc
    13681 ttaatgattt tacttccaat tcaatatcaa aaggtactgg tatcaattta agcacaataa
    13741 aaaagctgaa aagtggtgaa agatcagtgg aaaagctgaa tcttttagat gctataaaaa
    13801 taacggaatt tgctatgaaa aatggaaaag ctgagattga aatatggaga taattatcgt
    13861 ctagtgaatt acttgccact tagctgaatt taacgatcct tggtgcttga agggggagat
    13921 tcttgggaat agagcatact tgcaagccta tgtctttact aacaacgata tctcttatta
    13981 accaagctat ccccgtagtt ctaaggcttt tacttttatc taagcaataa tcgtattcaa
    14041 aggaaatttt tgacccttag aaagtctcat tttatcagac gtgagcttag gcattgctga
    14101 attttgttaa ttcggtttta ggttgtgctt tgagcataat atgaaagtat tctttatcac
    14161 gatttcattc atctaaggta atgtgatgtg attctgaaat tctttcaaag gcagtttttg
    14221 cataagctga cattacatca tcaatgacat gtttacaatg tttcactact aaaataaggg
    14281 ggtaaccaag aagaaaaact gaatgattat ttgtatctaa ttccatggta tatcaaccat
    14341 ttcctatata gactgattat gacatggatt aaaataaaaa ggcactatgt cttaattgtc
    14401 ggttttcgag ttaccgaatg gcattcatca cccacctata gaggatgggc gacttctgcc
    14461 tgaaataagt tacactactt ataacttcta ataaaattag attgagtcat tattatttaa
    14521 catcaacgat tttccagttt ccattttttt gtaatactaa tttgtactga aagtagctag
    14581 tggtttttga tacattatca aggtatttta tctttgtact cactagaaaa ttttttccgt
    14641 tttgtagata aactggattc tctaactccg aaaactttaa gtcaatattg attggtcgca
    14701 tcgcaccatt ttcaacataa tactccaatt ctttttcaga agctgatgga taaagtttaa
    14761 aaaatgtttc taaaaaatcg gtgatttctt ccgttgtttt ggcatcaatt tctgaatcgt
    14821 tttctacttg ttttgcttca tattttgcct tgtctggctt tccaatcatt gttggcaaac
    14881 tagttactaa atgattcctg ttttcatctt caaagattgt cactcgatat gcagaagaaa
    14941 ttgattgcgt cttttttccc tctgtaatat gttgctccac taaaaatgaa acgataaatt
    15001 cttccgagtg tttttcaaca tctagaattt ttacagattg aacttcggaa ctcgtgggaa
    15061 tatctgctcg aaccatatct tggattaaag cgagaccgtt ttctgtaagg tactgttcga
    15121 gattactcat tctcttttca attgcttctt tgttattttt ccatgaaaaa tattctttcg
    15181 caaaatcctc tgtaaaactt tcaacgccag aagtattcac taccttctct tttataacca
    15241 ctttttcatg agttgtatgt tgatcaatgg cggtgaaatt tttataaacg ccaaaagcaa
    15301 gactacaaga caataaaagc caaagggcaa gcaccatttt tcgatgctta cccacggata
    15361 caactcgttc ttttttcttt tttgggctct tttccttttg attccgttca atttttatct
    15421 tcattctttt tcctcttttc tcttatttgt atcggccagc tccgataaga tgctgccgcc
    15481 aatagttttc cgttagattc gtccacccca ctggatctcc tgcatgaaac atgcgattct
    15541 cccctgcgta aatgcccaca tgggtcacat aagtaccggc atcataggtt gaatgaaaga
    15601 aaactaaatc acctggtttg gcatctttta gatcaatatg agtcatggca tcatattgat
    15661 cctgagccac ccgaggaagt ttcaggtcaa ctttggcata acaccattgg gtcaagccac
    15721 tacaatcaaa ccccgtttct ggacttgagc caccaaacac ataggccgtt ccttcatact
    15781 taaatgcctc atcaaaaatt tcttggacta ttttgtcatc aaactgagtt gtagttaggt
    15841 attgcttcac taataaacag taaaacatat tgccataatt ataccgccac ccaccatttt
    15901 ccttaatcgc gattgggttg gggtaatcga ctttttgacc acctgatttt tcctttgaaa
    15961 aagattcagc taaagcaaaa ctatgcttct tcccgttttt cccgacatga tctagatacc
    16021 cgccaccata gttataggcc tgaataatac tatcttgatc acaccctagt tctttggaac
    16081 gcttaaccaa agacgcaaaa tagagacagc cttgtttgat ggatgcctcg gtacttaatg
    16141 aattaggtgg taatccggct gactcagaac tttgcataac gtcttccatt gtgccaccag
    16201 attccacttg aataatcgcc aaaagaattg gaatatactc tgttatatcc gattctttgg
    16261 catacttttc caccattgca cggtgtttca atacttcttc tgagacacta gttccgccag
    16321 gagaagtgcc agaactacca tttccctcac tgtcttcacc aaacaacaaa cccacacaca
    16381 tcaaaatacc cataaaagag atggtcagaa aagttaatga aataacaccc actttcttca
    16441 agttcatttt ttctcacctg accttgattt tggacgatgg ttcattcttt tttgtacttt
    16501 ttgattggtc tgctttggca gagtggacct ctgtttcact tgttggaaag aatttttctt
    16561 acttgctgat tggcttttcc cttttgaaat gatttcttga ctagttagtt ttcgtttgat
    16621 ttcgggattc agatttgctc tcacaatccg ctttggtgct tcttttttca gcatcatatc
    16681 tttctgaggt tgagctgctt tatctattgg aatattcgcc cttctttttc cctgacgatt
    16741 tgttgcttca ctcagtatct tgcgtttttc gtccattttc gcatttcttc gttgtcgttg
    16801 tttttctcgc aaatccactc gatccgcttt ttcttggaac agtccgcgct tgaattcttc
    16861 tggtgctttt ttcgactttt cgattccttt atggagattg tatttcaaat tcgttggcgt
    16921 attccttacc tgatccttta cttgtttagt cttatctttc accaaagctt gggtatccaa
    16981 aactttgccg atttttctcc cagccaaatt cattcgggat tgtttcttat tatttgaaac
    17041 tggattctcc ttagttaagt cagatagtat ttcgtgatcg ttcggtaatc gtgaattctt
    17101 tcgtagagaa gaaccggatg gcttaaattt ggattttgat tgttcctttg ccaacttatt
    17161 tccgactgct gcaccaccac caaaagccaa agctcgtccc acatttcgat tgagttgccg
    17221 caattttcga ttcattaaca tttgcggttt tcgcatgacg cgtcttccca ttgactggct
    17281 atcattactc tggaggttga acatactcat aatgtcgccc aatttgaaat agataccggc
    17341 aaaggtcaca atttgcagaa aagcaaccat gaaaaatgga taggttgccg aaatattgaa
    17401 aaacatcgtg gagatgctaa atgcagtcgt aatcaccaaa gtaacacccg ctcgcatcat
    17461 aatcgtattg aataaacgaa taatcgcctt ctttcctaaa ctttcataag tcggcaacat
    17521 ggacaataag aaactaattg gcagaaacat cgcaaagata atgaagagaa tttgcgagaa
    17581 caacataatc cctgttagaa gaaaaacaaa gaaggaaatg ccaatattga acaataccaa
    17641 aaagaccacg gtccctaaac ggttcatggt cttggtaata ctgagattcg cattgtcatt
    17701 gtcttcaatc tctgccttga ccgcttcttc ccgatctttg cctttgtttt catctggact
    17761 cacagataga atcttgttga cccggtcttc accaatttct tctatgttgg aatcatcaaa
    17821 ttgcagtagt aaccaaggtt gttggacttg aatcgaaaac aaactatccc gaatcaaatc
    17881 cacactatct tttccttggc tttctgaatt gggtacaacg atctcggttc caagggtaag
    17941 ggccgcttca ctaacatctg agctaaagtc attgattttt gtgatatagg taggcgcata
    18001 agcaatgaac gaacccgata gtagaaaaat catcacaaaa ttaatcacgg ctcgaactgc
    18061 tttcgtggtt tctcgtttta ataatccggt atacgccaca tacaccccca gagctaaaat
    18121 catcaataat agaaacccaa aataaaatcc ggaggtctgg agtccatttt cagtaatacc
    18181 agccaatgtt tggatattct ttccaatact ttcagccgta tccgaaatga aatctaattt
    18241 gtaagcctct tgaaccacat aacccgtggc gttcgacaaa tacaaactca ccgtccaaat
    18301 gaaattagta atggcataaa gaccatacat cacgcttttc cctaagccat caccccaatt
    18361 ccaaggcaac caatcccaag agctatccac aaagaaatct agttgatagt tgttcagtga
    18421 atatttggaa tatagatttc ctgcttcaac tgtatcatca actagccctg tcgcctcggc
    18481 taccgtacca actaaactca atagaactat cagagtgagt atgctaataa aaacgattcc
    18541 cacaatccga aaaagtttct ttttcatccc ctcactccat tctctcttga acaggtggac
    18601 gggtatcaaa ggcatggaag agttcttcaa agactggatg tacctgaacc acgcctaccc
    18661 gaccatacaa atcctgcatc aagcattggc cattttccaa atctcgtagg cgtttttgat
    18721 tgctttcatc ttctcgatcc aagccaaaga attccaaggt tttcttgatt tcatgaatat
    18781 cggtactgcg aaacgcaaac ttcaacccga tattattctt caagcgttca tccagtaaat
    18841 catcactatt ttgcgtgaca aagtaaaccc cggcattcat agcccgccca gcacgaacga
    18901 gcttattcga taatgttttc ccttgcgcta cttgaagaaa actccacgcc tcatctaagt
    18961 ctacaatttt gaagatttct cgattactat ggataaagtc caaggcaaaa gtggaaatga
    19021 cgattagcat ggaaacacta agcaattcca tggtggtata ttcttcaaaa gtggtttctg
    19081 catctggtaa aaccaaatcc gctacttgaa tgatatttaa ctgcctatct aaactaatcg
    19141 actgggtaat cgaaccatct gagaaaagca aatgggcaaa atcataatcg gtaaaggact
    19201 cgatgtgatc cgcgatattt tccgcaactg gtgagccttc ttttcgaagc tcattaatta
    19261 cttgtaataa tccccgttga ttgctttggg taaccgtccg aatggcctta cgcaacactg
    19321 gaaacttctc cccatctcga ctagaaattc ctgttaaaaa ggtcagaata tcaattgcta
    19381 gactttcaga atccttcttt ttctccataa tcacataagg atcaagtaat ccttgatttt
    19441 ttggcttact agttaagttg agaatattga tttcatccgc aatttctggc aaggtttctt
    19501 tccagccacc ccgttcccct tttggatcga caatcacagc ttgtccacca aaaaggacgg
    19561 cgtaataaac taagagattg ttactaaagg actttccgcc accgagtgaa ccgaggaatg
    19621 ccgctgctag cgcattggta actgaatcct tgaccccttg tgaggccaat gccggtttca
    19681 ggtaaacatt gcgccccgta tctacgttat aaccaaagta aatgccttcc aactccccta
    19741 acatctgagt ggcgccaaaa ccaagtccgg cgagaaaatc agacgtaaca tactggatat
    19801 aatcattcat gtatcgctta ctagaaggta agaattcttc atgtagcccc atcatatcgc
    19861 caaaaggccg gactagtttt acattggtat catcataaaa atctagcact tcatcacacc
    19921 ggcgctttag ttcatctact gattcggcac ttactcgaac cacatagctc agtttgtaca
    19981 tggattcttt ggactgatcc aaggtagttt ccaattcatc tacggaatcc aatgcatcta
    20041 agacattgga atttgtttca ttgtcagatt gataggcatg gttgtccaag tcttttaatt
    20101 cctttttctt attgcgaacg gtagcaagtg cctttttgtt cgtcacaatc tccacattca
    20161 tactagtgtc aattgggaat gtaaattgtt gttgctggta atagaaaagt tctgaggagg
    20221 gaaactccat ttcccccaca attgtattaa ttgttaagta cgctacatat gattcatgat
    20281 tctcatgttc catgcataag taccggggct tttcttcaat caaacaacga ctgggacgta
    20341 ataagtcgta acgtttcacc aaagtttccg acttcagctt tttctttggt agctgaaatt
    20401 catattcttc aaatggtgta cccttttcgc catagatatg ttcaatcaaa tacatcagat
    20461 cactcggtgt gactcgtctg actttaaatc ttcgagccaa tttactttcc attagttttt
    20521 caagcttggt atatcggcga atttcttcat tggataagga aacaaaatcg cccatcaaat
    20581 gatgattcac tccatagaca aattcttgaa agccggagaa gaaagatttc ttgagattct
    20641 ttagattgac ctcttcatct gtcgcaatca gtttgaagcc aataaaaaag cgataatcaa
    20701 tctgactatc gccaatcatg gatactaatg cctctgtctg taaatcaatt cgttgtttcg
    20761 ctacttctgt taatcgcccg gtaatttcct tttttgatcg ttcttgcgtg gcacgaatac
    20821 tactttctgt ggcaatttgt aaggcatgaa tcttgccttc acgattttgc gcaatcaatt
    20881 gacgaaagtt atcgtggact tgatatttct gttcaggtga caaaaaggag taattgtaag
    20941 gtattaactc atagtaggca aaacattctc cctcttgatt aaagacaaga ttattttcaa
    21001 tatacttaat cgggtacata gttcacactc cttaccagag taatgggttc gtcccatcgt
    21061 ttcttctgtt ctttgacttt ctttcctgcg aaagtgacct taaatcgtaa gtgatagcta
    21121 ataaaagatc gtaaaaatcc caatggtttc ttaccgtcaa acgttttttg cgacatgaac
    21181 caagtaactg ccaccggtat acctaagtat tttaaaaagg ccccctctat catagatagt
    21241 ggaggcacat gggcaaatac gatgacaaac agcaaggata aaacaaacca agccatctgg
    21301 ttaaaagtca caggaaaagg cagttgaaag tcattaattg cataaatgac cttttcaact
    21361 gcccaaatac tggtgtagct ttttattttc ttcatcaaat cattccttta aaaagaagga
    21421 tagtttagaa atcaactacc cttcaataat tttgttaata tggatactca aaaacacctc
    21481 gactcgttac caaataattg cctccaatct ccaagtctct accacacgca tcaaaatcaa
    21541 tatacgtctt caagtgttct ggtacttctc caaaatcacc agcttctaca atcaagaaat
    21601 atgctacatc actcatatca tcgcaatctg gataatagat aatatcatcc acatgctcta
    21661 ccatctcctc aaaagaattg aagaaagcat gttgaatctc agaagcaact tcaccaactg
    21721 gcgttccttc aagttcctcc gctaagccac acaaccgatt aatttcctca attggcgtat
    21781 actcatcaat ctcaaaggga agttcataat catgaattgc atattcctcg tattcgtcat
    21841 ttaacccaat tcgttctttc acttcatcaa aatcgacagg tggggtaaac cacgccccca
    21901 ccaattcacc ttcgttatat ttcccgaggt tcgcaatata aacacgcatc tgttccatcg
    21961 tgcttccccc ttacgcaccg acaattcggt taaacaaact gagtaagaca tccttcaccc
    22021 cagaagcatt aaagaccaat ccgaccgcaa tcaaagcaat caccaaaaag ccaatcagtt
    22081 tggaaaactc ccgcttaaat cctaaaaaca aaccaatgac cacaattgcc agtaagacta
    22141 aggattgggc attggttaaa aaccattgat atatggatag gtaagttcct gatattataa
    22201 atatctcaaa cttttccccc cattcacacg gagcgtgcga ctttcaccgc actccgcgtt
    22261 ccatcgtgtt tatattgaaa agtatttatg tagtagacct atatcaagtt taattcttga
    22321 ttgccagcta atactctata tttatttagt cttatgagct ggactttatt tagcttcaat
    22381 agagctatat atttttgtat tgtttcttct gttttagcgt gtattagacg gtgtaccgcc
    22441 tcttttacca aaataagatt tttataatcg tcatttccac cagctccagt tggtacaata
    22501 tgatgacaat gtatttcatt agcttgttga aattcttcca gagttatagc acattttcca
    22561 tgttgagcag aaaatagcga aattcgattg tctgcgtatt ctattgtgcg attttccaaa
    22621 gataatttca ttaactggta catcagtaat ttatcaacac ttagattggt gtggataaat
    22681 tttcttccct ctagagtgta gcaattcgct aaatacacct ttgccattgg ttttctgtgt
    22741 tggatatatc caacagggaa aataggttcg ccctcgccag caacataccg aagcatttta
    22801 gatttaccat atcttgttgc ctcctttgtc gtaagttgtc tgcctgtttt tctcaatctg
    22861 ccccttttgt ttgtacctaa tctgttagtg aagatagcca ttacagctct attcagtttc
    22921 atacaatcca gatttacatt cgttgcaatc tgataataat tttgcatacc taataccatt
    22981 gaattataaa gtcttgtttc ttctaattcc gttttccctt ttgagggaga agcaattttc
    23041 tttgcctgtg ataccagctt gtctttttgg tttttgaatt gtttatcact tatatgtgat
    23101 ttaacaacta acttctttct tctcggtatc attttaatct tgaaaccaag aaagtcggag
    23161 tatctttttc taacatttac aattcttgtt ttttcttgtg atacttccaa ttttaatcgt
    23221 tgttcaatcc attgagtgat tgctattttg gctttttcag cactttcctt gtagcggcag
    23281 aaaactctaa aatcatctgc ataacgaacc atatacattt cctttaactt tgttttcttc
    23341 atttctttgt aagcgttgct tttacatggg ctaccgcttt tattgatatg aaccacatag
    23401 ttttttgtaa caggattttc ctgccattgg ctttctaccc aatggtctaa ctcattaaga
    23461 acaatgtttg ctagtagtgg ggatattatt cccccttgcg gagttccttt ctctggatat
    23521 gttattgtac cgttagtcat tttgattgga gcttttaata tcctttttaa aatgaatatc
    23581 aagtgcttgt cccgtattcc catagcccat atctgtttta tcagcttgga atggttcacg
    23641 ttgtcaaaga aacccttaat atcaaattca atcacataat gtagctggct gatttgtagg
    23701 cggttatagg ttgcttttat tgcattttca actgacctat taggtctaaa accatagctg
    23761 ttttcactaa atttagcttc gcagattggt tctaatactt gttttataca ttgttgtata
    23821 agcctgtccc acatacaagg aatacctaga ggtctggttt taccatttgg ttttggtatt
    23881 tcttttcgcc tcactggctt aggtcgatac ccatgtggac tgcctgcaac aatgtatctt
    23941 acttttttga caactgtttc tgctggcaat ttgccaatat ctttaattat tgtaccgtct
    24001 gttcctgctg ttttactgcc tgcatttgct ttgatatttc gatatgccag taatatattt
    24061 tctctcgata ggataatatc cataagatga gtgaaaatat ctccattctt acttttggca
    24121 tataaatcat caaaggtgtt ttgcatttcg taatattcag cgtgtcttaa atcttctaca
    24181 cacaatgttt catttttatt tttaggcata aggcttcact cctttacttg aaattgagtg
    24241 agctttttta tcttactcgt aatccttatt gaaacaacat aatattttct aatatataca
    24301 cgacttgagg gcattcctcc attctcatta caagaatttc ttaggttcgc cctctgcttt
    24361 tcagcattag ttcaactgct tattgttctt cgtcagttta ttctcttgat gagaacccaa
    24421 tacctttcct cgttccgata atcttatcta tacatatata tccttaggtc actagctata
    24481 agcctgctgg cttgataccg cctgtaacgt tatatggcat ttcataacct atattcttac
    24541 tttgccacac cagctacgat ttctcgtacc tttgcatttc tacaaagttc aaatttagac
    24601 ccgtacattc gctgtttcgt cagttcctta tagaacattc taaccataga tattttatag
    24661 acccccgacc tgttggatac gctacccacc tctggatagt tttcgataga agatatatgt
    24721 tcatcaacta ttacggtatc tttcagccgt ctttaccgag cttcaaacat tctgagtttc
    24781 ctcatacaat gcttgtcgga ggctcagggc aggcgtttca gagcgttact tcatcattcc
    24841 acctgtcaga ttatcagttc tcctaataac caaacttttt cgttctttta ttagtgcctt
    24901 agcttttcac taaggaacga gtcgcacata aattttgtcc gaaattcatc ttgtcacttt
    24961 cctttctttt ccattgctcg atccgctgct gcacttgcat tcatcaagca catcacagta
    25021 acaccaagca tactgccacc aaataccaaa aaaatatctt ttacaattcc catgacgatt
    25081 cctcttttca tataatcaaa ttttcaattg ccatactttg ttgctccaaa atctttttat
    25141 gtcggtctga taagcgtgca ttctgtacca tatcctggat ataggttgtc cgattcaatc
    25201 gatccaactc cttagccatt ttccacgtag gggcgacttg tcggcctagc caattcaagg
    25261 ttcgttcaat ggtatacggt tttggctcgg aagttaattg aatctctttc cgattccgtc
    25321 caataaaacg cccccattgt tcattcaagg gccagttggt tcgcctttta ccttctactt
    25381 tatccgcaaa tcgcaagtaa cgattgataa tggaaaacgt ggtgctctca atgctacgac
    25441 cttttaacaa atcttgaatc gcatgaaaag cacggtcatt tttcagtcga atctcaaaac
    25501 gatttttcgt ctcagtttgg tctaatggaa tccctaactt gatatattgt tcatagtctt
    25561 tttcatacaa acagaaataa acctcactct tgagactgcc gatatataag gtattgccca
    25621 tgccgtcctt ttcatcagcc tttaaaagtt ccccggaacg ataactttta aaggtacgaa
    25681 acaaggagat acattcttcc ttctgacatt ttttcgttag ctcaggtata tccaatagcc
    25741 ccactcgatc attgattgcc aagtccaagc gtttcatcac gccaccggcc tttagacaat
    25801 cctcgaaaaa gtcgtaccag ctacgctttt gagcgagtaa aaaagtttca aattgtcggc
    25861 aacctcgccc ctttaattct aaaagcacac ctttatcttc ttcatgagac aacatcacca
    25921 caatatcacc catgacatac tgttcttgat aggagtaaaa ggcataatct tcatggagca
    25981 tatactcaaa tttcaaatgg agaatttctt gaataatttt tcgtgcatcc gttgtgggaa
    26041 agcgaatcct tacatagtca aacagtaacg tcaaaggcaa atcgggatta aagctttcca
    26101 gttggtcaaa aattttcctc atggttttta tagatgcggt tacgccacca ttttctatct
    26161 gatttaagta cggccgacta agtccacaag ccgtagccaa tttattttgt gaaacgccgt
    26221 attcgttgcg tcggtctttt aatagccgat aatctaaatt ccgttgtgcc aagttctcac
    26281 ctccaaattc aaggtgttaa ctttttcaaa tgagttaaca cctatacaaa ttacttacta
    26341 tctttgatac aacaagcatt cttaatggtt gcttacttat tttttgtgtt tttgtacccc
    26401 cctgttagat acgggggtga gacatcatgg tcggctaacg ccgtccatga acaggcacag
    26461 caccacggag gatttctgct tcgcgaatcc tccgcggtca gcgcctaaca gtcagttgtg
    26521 ttggtttagg ttactcatct gtaataccat ttacttccaa ctctgctttc atttctaaca
    26581 agtattgacg aatatctggt tcttttgctt ggtccgcaat ccgctcaaat tctgcaatta
    26641 cttgatttat ttcaattcga gcatccgtct cctcattcat taaatatgga tcgccagcga
    26701 ctttgacacc attcttgcga atatcaaatt ttaaccgtcg caattgttct tctaattctg
    26761 ggtctgactg aatctttcca atcacccaat aaatttctcc aatcaactca tcataaacca
    26821 tgtacatcca actcttttaa tcttctggca atatcaaaaa tgaccggaac tgttacagag
    26881 tttccggctt gcttatacaa ctgactatct gaattgactt gagaatctcg atcaaaagcc
    26941 caatcgggaa agccctgaag tcgccaacac tctctaggtg ttagcttccg aatttgatac
    27001 tgatccgtga cgatcgcttg ttggtctcct gttagtaagg tatgaacact ctgttttccc
    27061 agacgacctc ggcgacttgt ggaattagga aaagccagat tcacactgtc ttctggcttc
    27121 acctcttgat attctgtttc attttttcga atcatgattt ttgtaccacc ttgtttcgtt
    27181 gacaaggtgg gggcggttcc agtaacttca taaactcgat taccttgttc aaactttccc
    27241 ggtaatagtc ctgctacaga gattccatcc cttgctggca gtgcgatttt gattccttca
    27301 tcacctgtta aggttggcgc tacgccatct gaaccataga cttgtccacc cattcctcga
    27361 ttggaaggat tgatatttac caaatttctg atgttttgat cagatgttga agacggtcca
    27421 atgataggaa atacttgttc ggtacatgcg tctcgagaat gtccgataag gaatatccgc
    27481 tcccggcttt ggggaatgta ggcctttgag ttaagcacct accactccac gtcatacccc
    27541 aatccatcca gcgttcggag gatcgtctcg aacgtagccc ctccttcgtg attgagcaat
    27601 cctcggacgt tctcaaggaa taaaagctta ggtcggagaa gagtggtgaa ccgagcgatt
    27661 tcaaagaata aagtacctcg agtatcggaa aatctttgcc gctttcccgc aattgaaaaa
    27721 gcttggcacg gaaatccgcc gcaaaggatg tccactggtc cgagggattg aataaactca
    27781 tctgatacac ttgtgatgtc atgcatttcc acctccttac ttgtatcatg aattgcttta
    27841 taactacgtc tagcaaattt atcaatttca caaaaaccga tacaatgatg gctcgcctgt
    27901 tccataccta aacgaaagcc accaataccg gcgaataaat ctaaaaatct catacattac
    27961 ctcattcatt gcaaagaaaa aagccaagaa cattttgctc ttggctcata cattattaat
    28021 ttgtcctact attttttatt taatccaact aatttccgtt gtttttcatt ggcctgatcg
    28081 gctacatatt taatcaccgt tttgaactct tttgcagtag cattttccga taaatccgca
    28141 atgctcttat tgtatttctt tacaattttc gttacttgtt ctttctcagt catgtaattg
    28201 aacctccaaa tctttcctac tataccctag tggtaaaaat aattctagat tatccgtagc
    28261 ataatgaact tcggaaatat tattcgtata atcttttatt atgatatgaa gcaatacatc
    28321 tggatgttta ctctttactt ttgcaatgtt ctctcttgat ttgaaaaaag cgttaataaa
    28381 tgcctttttc ggcacatgac gtccctctgc aatttcacgt tcttgtgtaa atttccaagc
    28441 gattttaggg tcttgataaa catagaaaat cgtcactcga aaatgttttt tcaacgcccg
    28501 cgagatattt ttttcagcac ttaatattgc aaaagttgca tccagaataa aagaatagcc
    28561 atgatctaag acatatctaa atgcctgctc taccaaccaa gaagatgctt tttgaaagag
    28621 actagagttt tttccattat aatcaggaaa ctgggtgcga aagtaatccg catcaataat
    28681 cacatggtta tcataattct cagctaatcc aatggcaacc tctgattttc cagccccagg
    28741 actccctgcc ataaaaactg cgtctcgtcc aacttcgggg gatttccctt tgataatata
    28801 agaaataaac ttatccttat ttgcttttgc atactctaaa taagaatcat tactttccat
    28861 attaattatc ccctttcttc ctactatata aaagtattat acgttacttg aagtataaag
    28921 tcagtattga agatcactca atcattcatc ttttctaatt tactaattga atctaagaaa
    28981 tcataccctt ttggtacaag tggcgtataa aactcactaa tcacactgcc acctgtatcc
    29041 acataacctc gacctttgat gtgcttcata aagaagtttt tttcgacctc cccaaacatc
    29101 atggaatatc cgagttcact catacgaccc aaagccacgc gaaagttgaa ttgatcgcgg
    29161 attccgtctc ctaaatattt cgcatccggc ctttggcaag ccaaaatcag aaagaaacca
    29221 gattgacgac ccaacatcac gatttgtttg agcttattca aaatcaccgc actttctttc
    29281 gtcgttaaca tctccatata agccacgtat tcatcaaaga ttaaaaagtt gggtggaagt
    29341 ccaagatagg cataattctc tcctgttttg tagttagaca tttctttcat tgccttgcta
    29401 cgagccatca tacgttcata gaaatcttcc acacaagcag aaatttcttc cttttgtgaa
    29461 taaacatgag gcatcaccgt acctaaatca gctaaatctg catttttggg atcgaggata
    29521 aacaattctg catctgactt caatagtgct tcgataatgg tgaggaggaa ataggtcttc
    29581 cctccacccg tgccaccagc gattaacata tggggtaaag aatcataagc ccatacttga
    29641 tttttcatca atcgcagagt cccattttct gccactactt cgtctatccc aattcgattg
    29701 gcgatcatat catacagtaa agtatactcc acataggagt ctttgagttc cttttctact
    29761 aactcacaat acagtccgct ttctaacttc ttttccaatt ttaaaagctg atcttggtat
    29821 ttcccaagtg aaatttgaac gcgaatagac agtaatccat ctttcattcg ataacagatt
    29881 ttggggaagt aactgatagt ctctctggtt cggctactat tcaaatcttt gaaaaagcct
    29941 tcactttgag tttgtttcac ttcataccaa tggttctcta gaatcatccg agctagcttt
    30001 tgtcgatgcc acaagcttcg ccaatgatca agaaaaaagt gaatataaag caatatcata
    30061 gctcctgaaa aagcgagact tccaagcaga catactaaat cttttataga ccaaacgatt
    30121 tcaatagtag aaagtgatag cttagaaata tcaaattgtc taaactcttg aaaataaaag
    30181 acgctcatcc aaccgatgaa cagagcgagt agccagccaa gaacaaagtg ataaaccaag
    30241 tgctgatctc ctgcgcgtat gcgatgtcct ttgtacattt tgatggtttc cacctccaat
    30301 cgaaaaagcc caataggatt tcattaggca atttcaaaaa gttatgctag tcatttactg
    30361 ctacgaggag gggagttgtt tcgtttcaac caattgattt aaaaagcctt caatagcatc
    30421 cggcatctcc acaccaattt cttccaaaat ggattctgcc tgccgacata agttttcatt
    30481 tacttcgaca actataaaga aagactcttc ttctcctaac cagtctagta catcagagtc
    30541 ttcttcactg tcgctatttt ctccaagtaa accttgatgt ataatcagaa acattttttc
    30601 atcagaggtt aatgctttaa cgagttgttc ctcagtcagc tcgccttttc catattgatc
    30661 gagacaatct aaaatatgtt caacattaat ttccataatc ttcacctatt tctttctttc
    30721 attttggttc gtaggatttc cttgattcgg ctgccgcttc aagactaaat catccgcctt
    30781 aatgaaccaa ttaacggtag ttccttctcg aaaaacataa ttggcaacgg tatccacgat
    30841 tggattgacc aactctacct ctgcatcata agcaaactcg cgtaagggta cattagctgg
    30901 gatactaact tgaatcattc gcccttgtgc agaggatttt aaattatagg ttcgttcttt
    30961 tacctcatta ccaattgttc catcctcatt ttgcttccgt acttctcggc gtaatgcgga
    31021 aaaacgcaac ttcccaaatg ttaaacctga atctacgaca ataccttctg ttaatctcat
    31081 cttcttttcc tcctatgctt tcactaaatc atcaacatac aacacgtaat cagtaaaccc
    31141 acgattctca atctcatagc ctttggcaac caaatgggga ttcacggctt ttagcggttg
    31201 gtcttgatca aaatcctttt caccggcttc cgcagctact accacctcaa tatcatcggc
    31261 ccgttgctta ctggaataca aatgataact gcgaccaatc accgtagtat tccgtccata
    31321 tccttctgtt ataatttctc cttcaccggc ataacttaac tttccaaagg tttcagccat
    31381 atctggcacg acaaatttca attccatctt cttttcctct tttcattgtt agttttggat
    31441 acaaaaatag cgcgactact tttttaggag gcggtcgcgc acgttggttc ttaggattta
    31501 cttgtatcat ctcatcacct tagttccggc gattccagaa ataatagccc gccgtcgcaa
    31561 aaatcaaagt aaaaccaatg aacagtaaaa cattggaatt tttctccccg gtttgaggga
    31621 aggtcttcac tgtgggacta gattcttgag agccacttgg aacagttggt gtttccggtt
    31681 gtttcggcgt acttagtatg gttggaactt cttttggtgt taaggtttga gatttttctt
    31741 tcaaatcttc attgtgtttt ccattgatat tcccatcttt atcgtaattg atttccgcaa
    31801 aagtaaactt ggttccttct ggatattttc cggtatctac ttttttcgca agcacagttt
    31861 tggtgaattc tttatcattt acttcataat caatcttgcc agatttccaa atttctttgt
    31921 ttgtaccatc cggtaataaa gcatacagaa ttgtttcgaa agcttctttt gagccatcca
    31981 gtacatcatg agtaatcgac acatcatcaa acatatccac cacatcacca tgagtaaagg
    32041 tctgagaacc gttttctagg tgggcctttg tttggataga aacatggtgt tccactgtac
    32101 aactgacagt ttgggcttgg ttattcaagc taacatcctt cgctactggc ttatcgcctg
    32161 cttcaaaagc ttccttattt tcatacacat agttgaataa gacaatagtt ttatttaaaa
    32221 cttgttcggc ggttaattta tgctgaattt tccaagttcc tgttttctct ttgttcgcca
    32281 acgttgcgct tgtttctgca atcaccactg gtttggcttt ttcatctttt tcttgggcag
    32341 cttttgtcgc atccacatca atggcttgcg ctaccacata ccagtcttct ttgatttcat
    32401 gtagattgta actcaattta tcaactagct cggtagaatc cagagaagtt aattctttgt
    32461 ttccgtcttt ccaagtcgca agagaagtta aactatcttc ttcctcaggc aaatcataga
    32521 gcattaaacg gttcaaacta acagaaaatg ctttgttcgt cagcttctcg taaggaacgg
    32581 tcaccgtttt aattggttgt ttttggtctt gttcggtaat ggtaaagaca tactcactct
    32641 tcacaaagtc ttctttgttt tccttaaaag tagaacggat ttctaatggc gtaatctttt
    32701 gaaaaccttc tggggcttct acttcttcaa gtaaataatc cccataagga agattttcaa
    32761 acttgccata accatcaaac cctaattgct cgttataagc tgtggtcgct tcatcttcgg
    32821 cacctgtgat ttcattggtc ccttccaatg gcgacacttt aaaggtcaga tcattgaagc
    32881 cagtttcggt agtgcccgca gctgatccag caaatttaaa gaaatcaaag ccaaagcgaa
    32941 tcacttgttc ttttgccgta acatttcggg taatcacggc atttttttcg ctatcatcca
    33001 cctttttgat ggatacagga tactttgttt catcaaggct atatccttcg ggcgcttttg
    33061 tttcttgcca ataatactcg ttgatagcta aatgtttaac ggcaacttgg ttcttttcgt
    33121 ctaaagtcaa agtgaccgtt tcatcagaac ctttcgttcc cttcgctaac tctggtttaa
    33181 aagcctcact ccatttaaca gcttttccat ccttagcagt aaacaaggtg tattcagcac
    33241 cctcaaagac tgccttacct tgtgctttat ccccagtatc tttgtcttct ttcgtcaaag
    33301 tggtttcgcc agtgacttct tgattttgcc cttttacgtt actggtaaca ggggctacgg
    33361 tttgattggc atacttcaat tcgactttta caggtttgaa cgtattcacg aacccatgac
    33421 tagctttagt ttcggtcaca taataggttc ccaattccaa cgcattagca atctcttttg
    33481 gtgtttccgc atgaccgttt tcatccgtgg tcatttcttg aacgatttca ccggttggac
    33541 tgtctttgcg aatggcaaac gtattaccag ctaaggaata attgtcattc caaagatcac
    33601 tccctgtttc aactccgctt ttatccagaa tgatttgccc tttttcccgt gcgttttttg
    33661 aagtcacgta aatggtttcg cctgctttaa tggtggtagt catgggggtg gtatcaatcg
    33721 tataaggcgc cggtactgat ttttcggtaa tggttacttt tgtaccatga ggaatctcat
    33781 ccaatgtagc aatgccttct ttgtcagtag tcacgtcttt tgcaggtaaa gtttttccaa
    33841 agtctaaatg gaaaaccgtt cctggtacaa catcacccga ttctttatcg acttttttga
    33901 tctttaaaga accctccgtt tccacatcaa ttttgattgt gtaggtatta ggtttatcaa
    33961 tcgccccggc cattaaagtc tgttggccag cctttttata ggcgacaggt gttccggtac
    34021 cagcagattt cttaagcgtc agcacaccac tttcttttga attggcattt ggggtgatta
    34081 tcaactgatt accattcaca cgataatcaa tgtttgcggc attttccaca acctcatcga
    34141 actctgacaa attcagatta ttcgtatccg tcacagtagt cgattgccct aatactgttt
    34201 tagccgtact attatggaag gttggtttct tctgataatc gtcaatggct tgatttattt
    34261 ttgcctcaat ggctgcgata tttacggcac taccatctga tcgttttatt gagtgaaggg
    34321 tatacccatt aacttcttgc cagatcatct tctgtgccac aatatgagta tctgcatctg
    34381 tacctacttt tttccataaa acggaaacta atttggcttt atcggacata tctggtaacg
    34441 ggtttttctc atagccagga gtgaactcat tgtaaatcgg gactcctggt tcaatacaga
    34501 aaatatcttg tttaaagccg ttgtacactg cataatgcgg aacagtgact tctgacattg
    34561 gacgaccatc actaaaagtt ccttcaacag catattgatg tgctaaatct agttctacgg
    34621 ttaccgtttg tggatgggta atttcatcag caaaagtaat cgtaggagca attgctccaa
    34681 caattgcttg aacagccaaa ctcaaaatag ttaatacaca taatttcttt ttttgttttt
    34741 tatacatgaa atgttctcct ttcaaattaa gcacaaaaaa ataagatgct cgcttgaaca
    34801 tctttgttta taaagtcttt ttaaaatttt tattgactga atagaatgga tttgagaatg
    34861 aatgagccta aaaatttaat ctaaaatacg aaatatactg cctttaaatt agaacacatt
    34921 ttagaacaca aacatttcaa atttaatcaa atataataaa atatatttac gggaaaacct
    34981 ttataaatca aggtttttca aacttattca atgatacgaa gaaaaaacca ggtcttaaga
    35041 aagcccgtaa agcttcacag ttctcaaaac gttaattgcg attatcgttc gagttcacga
    35101 gttacgagaa tcgtactggg cgaagcaatg ctgagcgcag ttaccttaat cctaactttt
    35161 ctggcacttt ccacaatttg gaaagtgcct tttttgtgtt tttagctatg ttaataggta
    35221 ggattcttgg tctataatat cattcgatct ataaacaaac gggaaaaaga taaagtatca
    35281 tcaaacaata ttatttatcc gcttctgagg ttgtgacaga agtggtcagc ttcaagaaat
    35341 aagaaggaat ttacaaaaat tgcttctcat gtttgataaa tattgtgact tgtgaccgag
    35401 gagttggcag gagaacaccg tttattcgga agaagggatt gtgaaaagtc ttttgtcata
    35461 acctcttatt tggtagctaa ttgtaaatcc caaacggcat gtattatttt tcataagtcc
    35521 gtttttaagg attaatgttt tcttttgctt tttatatggt ctggcttcag cgagaagttc
    35581 caacgcatat acaaggacga cttatgtcaa cgataacaac gattaccatg gtggccagtc
    35641 cacttggatt agcactgttt ggtgcgctct ttgattggaa gacaacgcaa ccacgtctgc
    35701 gagacagtct aatttttctg ggagggagtc ttgctatagt tatccttata accggtctgg
    35761 taaaattact caagcttgat ctgaaagaag caaaaatttt cagtgaagag gaatacagag
    35821 aaacgacttt ggtcgaaaag aaagaatcag gaaactgata caagcgtata acaaactgcc
    35881 tgataatagg aaagacacgt attgtccgat tgtttttttt gacattcaat tggaaaattt
    35941 acactttctt tatacatttc tggctgcttt ctttataccc gtcaactata cttcactcat
    36001 caataagaaa gaaggataag tatggatttt ggaaatgaaa cggtcttgaa agcaactggt
    36061 ataaccaaaa aatacggtgc tgccaaagca ttagataaag tatcaatcga aatcaaacgt
    36121 ggaatgatct atggattgat tggggaaaat ggagcgggta agtctacctt tatgagaact
    36181 attatgggtt tgatctcgat tgatgaaggt tcgatcgaat tatttggaac gacggatttg
    36241 caggcagcaa gacgacgtat gggtcaatcg attgaaaccc ctgctcttta tccagaatta
    36301 actgcaagag ataacctacg tatccaagca gcgaacggcg gtgtgtcgga tagagaaatc
    36361 gaagacctgc tgaaaatgat gcgattggaa aatacaggga aaaagaaagc aaagaatttc
    36421 tctttaggta tgcgccagcg tttagctatt gcaaatgcac tgatcacgaa tccagaattt
    36481 ttgattttgg atgaaccgac gaatgggatg gatccagcag ggatggcaga aatgcgagaa
    36541 atcatccaac gtttggtaaa agaacggggc atcaccgtct tgctttctag ccacttgcta
    36601 gatgaattgt cacagatcgc cactcactat ggtattttgc atgaaggaca cttgatcaaa
    36661 gaattatcga aagaagaatt ggcacaagaa tctcgtcaat ttataaaaat tgacacttcg
    36721 gcgacggaac aagcagtaac ggttctcgac tctcttggtt atagggatta ttttgtacaa
    36781 tctagccgtg ttatccagct ttttgaagga attgaccaag tagcagccat caatcaagca
    36841 ttggtagaag caaaagttcc tgtggatggt attcacctag ttgggcaaaa actggaagat
    36901 tatttcttac aattaactgg aggcaatcca catgtttaat ctattaactg ctgaaaaaat
    36961 aaaagtatgg aagagccgta aaatgtgggt ctcactagga ctgatggtcg tacttccgct
    37021 tttttattct tggaacgaat ggtatatgca tacaaaatac ggcaatgaat taaaccaagc
    37081 aacggataca gtcatcaacg gtgcaacagg gattttaatg gtagaaaaaa tggctgcatg
    37141 gattcttctg gctttcgcag catttgcgtg cttttatatt ggggaagaat ttcaaaacgg
    37201 tacgattcgc aatacgttat ctttaggacg gaatcgaatg acttattatg tgtcgaaact
    37261 tctcgttacg cttttgatca caacacttgg cgtggttttg atcacgggac tagccatgct
    37321 tgcttacaca cttgctttcg gatttggtga agttgaggga atcaaaaact atggaaatta
    37381 tgttctaaaa gtatttcctg tattgcttct gctgacatta gggacattat ctgttccagt
    37441 ggctttgaca ttcatcacta gaagtaccag tgtcagtttg cttctttctt ttctttatat
    37501 catgggaacg gccttcattc ccggtgtttt cgcaaaaatc aaaggcttgg aatttctaac
    37561 ggagtggttt acggaaacgt ggctcatgta tacggacttt gcgcaacaag caacttattc
    37621 gcaagcaccg aaaatgattc tggtcagtct agtaacaatc gtggtatcat cagctctagg
    37681 aatgtttatt ttccaaaaat ctgacattaa gtaggtggtc ctgctggaaa ctattttgat
    37741 tatcgaagac gatgaagctg ttcattcctt actggaggag gttcttgaac agagatacaa
    37801 acttcttgat gcttattcag gtacggaagg aaaattattg ttaagcacat atcctgtcga
    37861 tttgatcctt ctagatctca tgcttccagg gctttcaggt gaagcattgt tagcagaaat
    37921 ccgacagaca tcgaatgttc cgatcatcgt tctttcagca aaaagcgatc aaagagataa
    37981 agtttccttg ttggcagcag gagcggatga ctatgtgacg aaaccatttg atatcgaaga
    38041 acttttgtta cgaatcggca tccaacttcg tcatcagact tctgtccaag taaaagatct
    38101 gtcgcaacgc atctattaca aggaaatctt actggacaaa gagtcgaggg atgtaaatgt
    38161 gaatggtgtg gctgtccatt tgacaggaag agaattcgat ctgctgaagc tttttttaga
    38221 acatccgaaa aaagtatttt cgcgagcaaa tctttatgaa acagtttggc aagaaccata
    38281 ttttgatagt gagaaaacag tgaatatgca tatttccaat cttcgaggga agctagcaaa
    38341 ggcacatgct gtgtatattc atacggtgtg gggagtgggg tttagatttg attaaatggc
    38401 tgttgcttct cgttgttatc tttatgggaa gttttatttt cttcctgcaa agggaaatca
    38461 agagattaac taagaaaatc gccactcttt ctgaacgaca agaatatggt ggtcgtcttt
    38521 cagtcgaatt tcgagaaaag aatctaatgg acctagtaga tgcactgaat acatggttgg
    38581 atgaaaatga acaaaaagga caagcatttc aagaaatgga agaaaacatc agactatcga
    38641 tcgtcggcct ttctcatgat ctcagaactc ctttgactgc tattaacggt tatgtacaat
    38701 tactggaaca ggtagaggat acggagaaac gggagaagta tttaacgatc atcaaacaat
    38761 ctgttgcaag attactcagt atgacggatc agttttatga tcttgctcga atagagacga
    38821 agcaaaaaga aatggatctc catacgcttt ctttttctaa agaggtggaa gaagtatttt
    38881 tctcttttta tgaacaattt tctgagaaaa atatcgaggt agcgttcgct gaacactcga
    38941 taaatacaac tgtattagca gatccgctca tgttgctgcg agtgctgcaa aatatcatac
    39001 agaatttatt gcgttatgca gatggacaag caaaggtgac attttcaaaa gaggatccat
    39061 tcattcgatt aacagtggcc aatcctatca aaccaggaac gcaaacctct gttgaaaaag
    39121 tcttccagcg tttttatacc gaaaatacca gccgcacaaa tacggaatct agcggaatcg
    39181 ggctttacct gtcaaaaaaa ttggtggaag gaatgggagg agagatgacc gctagattag
    39241 acgggggcat cttctccatc tccgtcaagt tgcggagggt ttaattatac aagattagtg
    39301 agaactagta gaaaaatgta ttatcttata tatatttaat agagaaaaaa gcctgtgata
    39361 taaat
//
LOCUS       DAPBAF010000028        39008 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.028, whole genome shotgun sequence.
ACCESSION   DAPBAF010000028 DAPBAF010000000
VERSION     DAPBAF010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 39008)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39008)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39008
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.028"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(178..735)
                     /gene="frr"
                     /locus_tag="RD451_001613"
     CDS             complement(178..735)
                     /gene="frr"
                     /locus_tag="RD451_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HDT7566876.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(738..1460)
                     /locus_tag="RD451_001614"
     CDS             complement(738..1460)
                     /locus_tag="RD451_001614"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HDT7566877.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(1596..2477)
                     /locus_tag="RD451_001615"
     CDS             complement(1596..2477)
                     /locus_tag="RD451_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HDT7566878.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(2576..3358)
                     /gene="rpsB"
                     /locus_tag="RD451_001616"
     CDS             complement(2576..3358)
                     /gene="rpsB"
                     /locus_tag="RD451_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HDT7566879.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            3717..4196
                     /locus_tag="RD451_001617"
     CDS             3717..4196
                     /locus_tag="RD451_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgR family transcriptional regulator"
                     /protein_id="HDT7566880.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            4413..5504
                     /gene="phnW"
                     /locus_tag="RD451_001618"
     CDS             4413..5504
                     /gene="phnW"
                     /locus_tag="RD451_001618"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HDT7566881.1"
                     /translation="MYKLLTSGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSSSFGVESVLSSVIRPEDTVLICSNGAYRQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQERDLL
                     FIVDAMSSFGGIPICVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            5497..5625
                     /locus_tag="RD451_001619"
     CDS             5497..5625
                     /locus_tag="RD451_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HDT7566882.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGTQLTDKEIR"
     gene            5629..6174
                     /locus_tag="RD451_001620"
     CDS             5629..6174
                     /locus_tag="RD451_001620"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HDT7566883.1"
                     /translation="MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEH
                     YLFKDLVKHSTLKPDTLETIERLRNAGINIGSTNGFNAPMMTIVAETAKKERYSPDFM
                     ATFEDVEGYGRPFPYMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEG
                     SSLMGISYDEYQKLEMGKKIV"
     gene            complement(6628..8319)
                     /locus_tag="RD451_001621"
     CDS             complement(6628..8319)
                     /locus_tag="RD451_001621"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HDT7566884.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDKEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMHHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(8739..9686)
                     /gene="arcC"
                     /locus_tag="RD451_001622"
     CDS             complement(8739..9686)
                     /gene="arcC"
                     /locus_tag="RD451_001622"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HDT7566885.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(9801..10820)
                     /gene="argF"
                     /locus_tag="RD451_001623"
     CDS             complement(9801..10820)
                     /gene="argF"
                     /locus_tag="RD451_001623"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HDT7566886.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(10911..12140)
                     /gene="arcA"
                     /locus_tag="RD451_001624"
     CDS             complement(10911..12140)
                     /gene="arcA"
                     /locus_tag="RD451_001624"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HDT7566887.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDAFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
     gene            12601..13302
                     /locus_tag="RD451_001625"
     CDS             12601..13302
                     /locus_tag="RD451_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HDT7566888.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
     gene            complement(13911..14927)
                     /gene="tsaD"
                     /locus_tag="RD451_001626"
     CDS             complement(13911..14927)
                     /gene="tsaD"
                     /locus_tag="RD451_001626"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HDT7566889.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIIAGGVAANQ
                     GLREGLQDALATKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(14924..15388)
                     /gene="rimI"
                     /locus_tag="RD451_001627"
     CDS             complement(14924..15388)
                     /gene="rimI"
                     /locus_tag="RD451_001627"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HDT7566890.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLAEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            complement(15395..15937)
                     /gene="rimI"
                     /locus_tag="RD451_001628"
     CDS             complement(15395..15937)
                     /gene="rimI"
                     /locus_tag="RD451_001628"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HDT7566891.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTVEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            complement(15921..16643)
                     /gene="tsaB"
                     /locus_tag="RD451_001629"
     CDS             complement(15921..16643)
                     /gene="tsaB"
                     /locus_tag="RD451_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HDT7566892.1"
                     /translation="MITLGIDTANQTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAID
                     QLFADLQISPKDIDRIAVSDGPGSYTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAAN
                     CIGVDNIIVPMFDARRKNVYAGAYRWKENRLETVLEDVHISASDLFTQLQKLNEAIYF
                     VGSDCHKFFSEIKEILPSAMINTVPAWDIPSGVTVAQLGALVEPVAEKQAFLPRYLKR
                     VEAEEKWLETHTPGDESYVEKI"
     gene            complement(16834..17814)
                     /locus_tag="RD451_001630"
     CDS             complement(16834..17814)
                     /locus_tag="RD451_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDT7566893.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPADGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            complement(17838..19322)
                     /gene="galT"
                     /locus_tag="RD451_001631"
     CDS             complement(17838..19322)
                     /gene="galT"
                     /locus_tag="RD451_001631"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HDT7566894.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLEDYPQVIAGVVKWPMSVIRLQSTEKNLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            complement(19334..20323)
                     /gene="galE"
                     /locus_tag="RD451_001632"
     CDS             complement(19334..20323)
                     /gene="galE"
                     /locus_tag="RD451_001632"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HDT7566895.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREILGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
     gene            20571..20738
                     /locus_tag="RD451_001633"
     CDS             20571..20738
                     /locus_tag="RD451_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HDT7566896.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            complement(20800..22611)
                     /locus_tag="RD451_001634"
     CDS             complement(20800..22611)
                     /locus_tag="RD451_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HDT7566897.1"
                     /translation="MKIGIIGAGPRGLSVAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNVLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSRGGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGAMAWPRLLTNENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLETPLAYQNEPFSEASRIFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPIIRTKELAALIDAGIFHLIEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(22608..22973)
                     /locus_tag="RD451_001635"
     CDS             complement(22608..22973)
                     /locus_tag="RD451_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 family protein"
                     /protein_id="HDT7566898.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            complement(23136..23531)
                     /locus_tag="RD451_001636"
     CDS             complement(23136..23531)
                     /locus_tag="RD451_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HDT7566899.1"
                     /translation="MVLWVINIILLLIVLAIILWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            complement(23549..24511)
                     /locus_tag="RD451_001637"
     CDS             complement(23549..24511)
                     /locus_tag="RD451_001637"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HDT7566900.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRFLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACGNLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            complement(24511..24723)
                     /locus_tag="RD451_001638"
     CDS             complement(24511..24723)
                     /locus_tag="RD451_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HDT7566901.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            complement(24744..25442)
                     /locus_tag="RD451_001639"
     CDS             complement(24744..25442)
                     /locus_tag="RD451_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HDT7566902.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            complement(25462..26004)
                     /locus_tag="RD451_001640"
     CDS             complement(25462..26004)
                     /locus_tag="RD451_001640"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HDT7566903.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            complement(26136..27140)
                     /locus_tag="RD451_001641"
     CDS             complement(26136..27140)
                     /locus_tag="RD451_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HDT7566904.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIVLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILLSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            complement(27137..28126)
                     /locus_tag="RD451_001642"
     CDS             complement(27137..28126)
                     /locus_tag="RD451_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HDT7566905.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVGKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            complement(28123..28929)
                     /locus_tag="RD451_001643"
     CDS             complement(28123..28929)
                     /locus_tag="RD451_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7566906.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKIALLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            29095..30051
                     /locus_tag="RD451_001644"
     CDS             29095..30051
                     /locus_tag="RD451_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDT7566907.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            complement(30128..30646)
                     /locus_tag="RD451_001645"
     CDS             complement(30128..30646)
                     /locus_tag="RD451_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HDT7566908.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(30734..30883)
                     /gene="rpmG"
                     /locus_tag="RD451_001646"
     CDS             complement(30734..30883)
                     /gene="rpmG"
                     /locus_tag="RD451_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HDT7566909.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            31111..31557
                     /locus_tag="RD451_001647"
     CDS             31111..31557
                     /locus_tag="RD451_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HDT7566910.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            complement(31752..33647)
                     /gene="asnB"
                     /locus_tag="RD451_001648"
     CDS             complement(31752..33647)
                     /gene="asnB"
                     /locus_tag="RD451_001648"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HDT7566911.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKIDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEKWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
     gene            complement(33972..34946)
                     /gene="bsh"
                     /locus_tag="RD451_001649"
     CDS             complement(33972..34946)
                     /gene="bsh"
                     /locus_tag="RD451_001649"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HDT7566912.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNGTPENHFSNQISLNVYSRGMGGLGLPGDL
                     SSVSRFVKATFTKMNAASGDSESESISQFFHILGSVEQQKGVCDTGERKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAVNMNKEDLDRHELVSYPVIKEQQINYVN"
     gene            complement(35280..35367)
                     /locus_tag="RD451_001650"
     tRNA            complement(35280..35367)
                     /locus_tag="RD451_001650"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(35333..35335),aa:Ser,seq:cga)
     gene            complement(35512..36078)
                     /locus_tag="RD451_001651"
     CDS             complement(35512..36078)
                     /locus_tag="RD451_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDT7566913.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            36334..37665
                     /locus_tag="RD451_001652"
     CDS             36334..37665
                     /locus_tag="RD451_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HDT7566914.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGGFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSALSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGLLLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLLGIREIFDSSGKLTT
                     DFIANSGIGATLINIGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
     gene            37631..37981
                     /locus_tag="RD451_001653"
     CDS             37631..37981
                     /locus_tag="RD451_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566915.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(38073..38492)
                     /locus_tag="RD451_001654"
                     /pseudo
     CDS             complement(38073..38492)
                     /locus_tag="RD451_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297629.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
     gene            complement(38493..38837)
                     /locus_tag="RD451_001655"
     CDS             complement(38493..38837)
                     /locus_tag="RD451_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HDT7566916.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVGWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
BASE COUNT        11318 a         8089 c         6766 g        12835 t
ORIGIN      
        1 ttaaaagatt cccactatct taagtattat agcaatatct aactgttttt cctatgaaat
       61 cattgttttt ttatttaaaa actgaatatt tttttctttt tttaattttt aaataaaaga
      121 aatataaata aaaacagagg aagcggaatg atccgcccct ctgtttttat gattttatta
      181 aacttccaat aattcttttt ctttatcagc agcgatctta tctacttctt tgatgctgtt
      241 atctgtcaat gtttgtacgt ctttttctaa tccgcgcaaa tcatcttcgg taatatcacc
      301 atttttttgt tgttttttat attcatcgat cgcatcacga cggatgttac gaatcgcgat
      361 ttttgcattt tctgcttctt ttttcacatc tttagctaat tcttttctgc gttcttctgt
      421 cagttgcggg ataactaagc gaatgacatt tccatcattg gttggactga ttccgatatc
      481 acttgccata atagcttttt caacatcttg aagaatgctc ttgtcaaaag gtgtgatcat
      541 taaaacacgt gcttctggaa tttggattga tgccatttgg ttcaatggtg ttggcgcacc
      601 gtagtagttc acagtaatac ggtccaaaag gctagcgttc gcacggcctg cgcggatttg
      661 cccaagttca cgttgaagat tttgtgctgc ttttttcatt ttttcttttg cttctgtcat
      721 aattgcatct gccattttta tttccccctt acagttgttc cgatattttc gcctaagatt
      781 gcacggcgaa tatttccgtg ttcatttaaa ttgaagacaa gcagtggaat atcattatcc
      841 atgcttagtg aacttgcagt tgaatccatg acttgtaatc ctttggcaat aacttccaga
      901 tgagtcagtt cttcaaattt tactgcattt gcatctactt tcggatcagc agaataaaca
      961 ccgtctacat tgtttttagc catcaggata acatctgcgc cgatttctgc cgcgcgtaat
     1021 gctgctgttg tgtctgtcga gaagtacggg ttgccggtac cgcctgcaaa gataacgatc
     1081 cgtccttttt ctaaatgacg ttctgcttta cggcgaatat atggctctgc gatttgacgc
     1141 atttcaatcg aagtttgcac gcgtgtcggt acacccacgt tttccaacgt atcctgtaaa
     1201 gctaaggcat tcataactgt agctaacata cccatgtaat cagcttgagc acgttccatg
     1261 cccatttgtg ctccgatttg tccgcgccag atatttccgc cgcccacaac gattgccatt
     1321 tcaacgccca gctcgtgaac ttctttgatt tcttggatga tttctttgat tactggtggt
     1381 ttgattccaa atcctgcgtc cccagctaaa gcttctccac tcaattttaa gactacacgc
     1441 tgatatttcg gtgtgaccat gttcattcct ccaatatttt ctattgccat tttaccatac
     1501 ttagatgatt tcgacactct aagactggtt tttcttgttt tgcttaaaaa aagggagcgc
     1561 acaaaccgtg cgttcccgtc tgttattcaa cagaattatt ttttcacttg gctcataact
     1621 tcttctacaa agttatcttc gcgtttttcg ataccttcgc caacttcgaa acgtacgaat
     1681 gttttaacag ttgcgccttt tgatgcaacg tatttttcaa cagtcatatc aggatcttta
     1741 acgaatggtt ggtccaccaa agcgatttct gctttgaatt tcttcaagcg tccttctacc
     1801 attttttcaa cgatattcgc tggtttgcct tcgttcaatg cttgttctgt aagaacagtt
     1861 ttttcatgtt ctaattcagc ttctggaatt tgtgattcgt ttacataacg aggattgata
     1921 gctgctacgt gcatagctac gtctcttgca actgtttcgt cagttgttcc atctagaaca
     1981 gtcaatacgg caatacgtcc gcccatatgc aagtatccac caaatgcagc attgtcgtct
     2041 ttttctacaa cttcaaagcg acggaagctg attttttctc cgataacttg agttgcttcg
     2101 atcaagtcag attcaattgt acctttatct gttttgattt tcattgcagc ttccatgtct
     2161 gctggtttgt tttcagcaac aagttctgca atttctttta ctaaatcttg gaacatttcg
     2221 tttttagaaa caaagtctgt ttctgagttt acttcaacga ttgctgcagt gttacctttc
     2281 acagcaactg aagccaatcc ttcagctgca atgcggtcat ttttcttcgc agcctttgcc
     2341 attccttttt cacgtaaaag atcaactgct ttttccatgt cgccttctac ttcaactaat
     2401 gcttttttcg catccatcat tcctacgcca gtcatttcgc gtagttcttt taccatttta
     2461 gctgtaacgt ctgccatgtt taactcctcc tgtgtgtttt tctttttaaa aaaagctgct
     2521 tcaaaggaga gtgaggcttg tcgcccagcc tttgaaacag ctccatcatt caaaattatt
     2581 ctgctgaaga attgtcgcct tcaacaacat ctacgatttc ttcgattgat gttgctgtgt
     2641 tttcttctgt gaaatcttct tcaactactt gatcttcacc ttggtttcct tcgatgaaag
     2701 catcagccat ttttgaagta atcaatttaa cggcacgaat tgcatcgtcg tttgaaggga
     2761 ttactacgtc gatttcatct ggatcgcagt ttgtatcaac catagctacg attgggatat
     2821 ttaatttgtg tgcttcttga acagcaatac gttctttacg tgggtcaacg atgtacatta
     2881 catctgggat tcttggcata tcagcgatac cgcctaagaa tttttcaaga cgttcacgtt
     2941 ctttgttcaa accagcaact tcttttttag gtagaacttc aaaagttcca tcttcttcca
     3001 ttgcattgat ttgtttcaaa cggctgatac gtttttggat agtatcccag tttgtcaatg
     3061 ttccgcctaa ccaacgatgg ttaacgaagt attgtcctgc acgagttgct tcttctttga
     3121 ttgcttcttg tgcttgtttt tttgtaccta cgaataatgc tacgccgcct tcttcagcaa
     3181 cgctcttcat gtaatcataa gctgcatcta ctaatttaac tgttttttgc aagtcaatga
     3241 tgtagattcc gtttctttct gtgaagatat atttcttcat ttttggattc cagcgacgag
     3301 tttggtgacc aaagtgtacg ccggcttcta gtaattgttt catagaaatt actgccatgt
     3361 ttgtttcctc cgatttggtt ttatttttcc tcttcttatc ttctaccttg ccggcaaact
     3421 ttttcaagca cctaccgaca atccaataag aatgtggatt tgctgatgca taaagcaccc
     3481 tcagctatta tacagacaaa agatccgtat cgcaagagca aatatacttt tctgctcaac
     3541 attcaatagt ttacctgaaa gataaaaaga attcaagaaa aacagtagat ttctctttgt
     3601 ttctttatta tcctttttcc ataaaataat tttaggtata aaagacgaat attattgggc
     3661 aatccttctt ttttttgtta tgatacatgt gaaatctttc gtaaaggaga aagaaaatgc
     3721 gcaaagctca aagacatttg ctgattaaac aagtcattga agaattcccg atccgtacgc
     3781 aagaagaact attaaacaaa cttgggcatt atggcgttac cgccacgcag gcaacgattt
     3841 ctcgagatat ccgtgatcta aaaatcgtga aggcacctga tgaaaatggc gtttcccgct
     3901 tcgtattgtt tcgcgaaaaa ggaactcctg agactaggac tgaggaagag gatcggctgg
     3961 ttcaaatgat tgaagacatt gtattgaaag tcgaacgagt ccactttttg acgatcgtca
     4021 ataccttgcc agacaatgct catttatttg catctgtttt agatgagatc aaacctccct
     4081 ctattgtcag tacaattgct ggattcgata cgatcatggt catctcggaa aatgaggagg
     4141 acgcaaaacg agtagaagaa tttcttcacc atccaactga agtatcactt ttttaatcag
     4201 agcacgtatt cctaatatgg aatgcgtgtt tttttatttt caatattttc cttattgaat
     4261 aaacctttac actctttaca aaaatacatc attttttatt caaatttttc aacaccttga
     4321 ttgaatcaca ataatcatca tttatattgg atgttaacaa gagcagcttc ttgctctttg
     4381 tgtatttcaa aaaagaaatg aaaggaaatc atatgtataa attattaact tctggaccat
     4441 tgacgacttc tgaaacagtg aaaaatgcta tgctgatcga tcattgtact tgggatcaag
     4501 aatacaaaga aattacacaa tggataagaa aaaaattatt ggatcttgct caagtatcgg
     4561 aaggaatata cacaacggtc ttaatgcaag gtagcagctc cttcggggta gaatcggtat
     4621 taagttctgt gatcaggcca gaagatactg tactgatttg ttcaaacggc gcatatagac
     4681 aacgaatgat caacatgtgc gaatgtctga aactgaacta taccgtttat gaggtatcgg
     4741 aacatcaaat cctccaagct catgtgatta cacagctgat tgaagagaat ccgtctatct
     4801 ccgcactagc aatggtccat agcgagacta cttccggtat tttgaataat ttggaagaga
     4861 ttgctgctgt cacacaagaa agagatcttt tgtttatagt ggacgcgatg tcaagctttg
     4921 gtgggatacc gatttgtgta gccgaactag ggattgattt tttgatttcc agctcaaaca
     4981 aatgtattca aggtgttcca ggcttttctt ttgtacttgc taataaagcg gaactggaaa
     5041 aacgaaaaaa tgttagccga agtttgtcac ttgatctata tgaccagtac cgcgtgatgg
     5101 aaaacgagaa tggcaaatgg cgtttcactt cccctaccca tacggttttg gcttttcaac
     5161 aagcgctgaa ggaactagag gcagaaggag gaatcgaaac tcgatattca cgttatctcg
     5221 ccaataatca tgtgctacga caaaaaatga cagagatggg gttccagcct ttcattcaag
     5281 aatatcaggg gccattcatc acctcttttc tttaccctaa ggactggcga tttgatttta
     5341 atcattttta tcagtattta aagcaaaatg gatttgtgat ctatcccggg aaaatcagcg
     5401 atcatgaatg ttttcgtatc ggaaatattg gcgagatcta tccggaagat attttggaac
     5461 tgacagcaat tatcaaagac tataaggaga acgttaatga ttaaaactgt aatttttgat
     5521 tgggcaggaa caactgtgga ctttggctgt atggctcctg tccacgcttt tagaaatgct
     5581 tttctagaaa aaggaaccca actgactgac aaagaaatcc gctaaccgat gggaaaatta
     5641 aaatgggatc atatccaaca gcttctttcc ctcccttctg tcaaaaaaca atggatagct
     5701 atttatggac aactacctca ggaaaaagag gtggaggaat tgtatcaaca atttgaacat
     5761 tatctgttta aagatttggt caagcattct accttgaaac ccgacacatt ggaaacgatc
     5821 gaacggttga gaaacgctgg gatcaatatt ggttccacga atggatttaa tgctcctatg
     5881 atgacaatcg tagcagaaac cgcaaaaaaa gaaaggtatt caccagactt catggcaact
     5941 tttgaagacg tcgaagggta tggtcgaccg tttccttata tgatccataa aaacatgcag
     6001 tacttcaaaa acaagtcggt tgatgaagta atcaaagtcg gagatacggt ctcagatatc
     6061 caggaaggga aaaatgccgg agtgttgaca gtaggtgtaa ttgaaggtag ttcgctaatg
     6121 gggatttctt atgatgagta ccaaaaatta gagatgggga aaaagatcgt ttaaaacagt
     6181 ctgttgctct tagattccaa caagccggcg ctgatatttg tgtaaacaat ttaaaagagt
     6241 taacagaata cattttgtac gctgacaaga atccagaatg acttttatac aaaataagag
     6301 gttgtgaaaa agctgtcctg tatcaagtaa taaaaacagc caagcaaaaa tagctcctca
     6361 tatttttcgt ttggttaggc ttattaccgc agatgcaagc ttttgaacac cgtttattcg
     6421 aaaaaaaaaa gggagctgtg acacgacttt tgtcacagtc cccttatttg caaacaaaca
     6481 gtgtttaaga gacaacctct ccactaaacg gtgttcattc agctgactct cggtatttgc
     6541 tcaaaaaacg ataaaatttg aaaagctatt ttctcttttg tttctctaat actcggatca
     6601 gaacgctgat ttcacattct ctttttctta catcttatct ggtgcatgaa gtcctagcaa
     6661 acgaaggtct tctttcaata atacagtcac tgcataaact agagctaagc gtgcttcttt
     6721 ttgttcatca tcagctaaaa tcttcgtatg agcatagtat ttgttgaatg cttgtgctaa
     6781 tttgattgca tgtttcgcaa tcactgacgg ttcgtatttt tccccagcag acaagaccgt
     6841 ttcagggtat ttttgaacta atttaaccac ttcccagctg gtatcgtcat tcaatgcata
     6901 gtctgctgtt tctgaaggga caaatcctgc tttttccaac aggctgactg cacgagcatg
     6961 tgtatattgc acataaggtc cagtttctcc ttcaaatcga acaacttctt ccaggttaaa
     7021 gtcaaatgta ttcagtcgat cgtttttcaa atcgtggaaa atgactgccc caaccccaac
     7081 ttgtttagct acagcatctt tgttttccaa atcagggttt ttctcgctga tttgttcttt
     7141 agcagattgg attgcttcat ttaatacttc ttctaataag acgatctttc ctttacgagt
     7201 tgataatttt ttaccacctt gcgtgatcaa accaaatgga atatggtgca tgtcgtcaga
     7261 ccagtcaaag cccatttcct tcaagacagc tttcaactgt ttaaaatgat agctttgttc
     7321 attccctact acatatagag attgtttgaa gtcgtaagta cgtttacggt acaatgcagc
     7381 agctaagtca cgtgtaatgt atagtgtcgc accgtctgac ttcttaatca acgctggatt
     7441 caggtcataa gcagataggt caacgatctc tgcaccttta tcctcgttca gcaaatgttt
     7501 ttcttctaaa agtttgacga tttcatccat cttgtcattg tagaaagctt caccgttcaa
     7561 cgaatcgaaa cgtacttcca gcagatcata gattttattg aattctttca tcgattcatc
     7621 acggaaccat tgccataatt gaatagcctc tttatcgcct tcttccagac gtttgaacca
     7681 agcacgagct tcttcattta attctggttc tgtttcagct acttcatgga attggacgta
     7741 taaacgaagc aattcattga ttggttctgc tttaacagct tcttctgtac cccatttttt
     7801 gtaagcgacg atcagttttc caaactgtgt tccccagtca cctaaatggt tgatgcggat
     7861 tggctgataa ccgatttttt ccataatgaa accgatcgaa ttaccgataa ctgtcgaacg
     7921 caaatgtccc attgagattg gtttggcaat attaggagaa gacatgtcga ttggtactgt
     7981 tccttgattc ccgatgttgc tatccccata atgttctttt tctttcacta ctgtttgcaa
     8041 aacttttttg ctgataagtt ctttattcat gaaaaagttc aagtaaggtc cgacaacttc
     8101 gattttttca aagttggcag aatcgatttt ttctgctaaa tctgcagcga tttgctgtgg
     8161 cgcttttcgg taaacttttg ctaatgaaaa ggctggaaat gcaacatctc cgtgttcagc
     8221 tgattttgga ttttctagta attgctcgac ttgttccagt gttaaatcat ctttgacagc
     8281 gtcatagaca gcttttgcga caagatcttt attattcatc tttattcctc ctaaagtgtt
     8341 cccttgattg ttaaacaaaa aaaatctcta gcgacggcat acttagtatg ccatcactag
     8401 agacgagatt tcccgcggta ccactccaat tgtcctaaaa aaggaccagc tccatctgat
     8461 atcggtagac gaccgtctgt ttaaaacaga attctccaag tgcgcttcgt tgtatcttct
     8521 tcattcggct tccaccactt ccgaattcgc tagccaagaa tgatacaagt actctcttgt
     8581 tcaacaaatc ttagtcttat taaactttct tgaattatat cagaaaaaaa aacgaaaggc
     8641 tagtcgtttc ataaaaaaaa aatccagatg gcctaaagga gaagaaatac cacctggata
     8701 gctataaatc atttcgtaaa tacgaaagac ttaacaaatt aatcagctac gataatcgtt
     8761 ccttcttcag aagctaaaag attctcgata ttttctaaag aagtgatgat tgccttagcg
     8821 tttggttttg cttcaacaaa tgcaatagct gcttctactt tcggaagcat gcttcctgga
     8881 gcgaattgct tttcatcaat gtattgtttc atttctgaaa cagtaacagt ttctaatttc
     8941 ttttgatctg gtttttggta attgacatac acattgtcta ctcctgtcaa tacgatcagc
     9001 aaatccgcat cgatgatttc ggctaatttt tctgaagcaa aatctttatc gattacggct
     9061 tctcgtcctt ctaatccagt agctgtttct acaacaggaa tcccaccgcc accaacagag
     9121 actgtgataa ctccttgatc gaccagcgtt tcgatgacac gtgcttcttt aatcgagatg
     9181 ggtttagggg aagcgactac ttttctccat ccacgtccag catcttcttt gaatgtcaca
     9241 gtggagtcag cattcatttg ttctttggct tcttcttccg tgtagaatgg accgactggt
     9301 ttacttggat ttttgaatga aggatcattt tcatccacaa taacttgagt gactaaagaa
     9361 accacatctt tatcgatccc tttttccttc agtacttcgc ccatggcgtt ttgtaaccag
     9421 taaccgatag atccttctgt cattgcaaca catgtatcta aaggcattgc cggtgttttc
     9481 tcagaatcag cagcttgctg ctgaatcaat aggttaccga cttgcggacc atttccgtgg
     9541 gagatgatca attcatctcc ttgttcgata aatttcacta aatactttgc tgtttccatt
     9601 aacgcttctt gttgggcttt tgcacttgca tccgtagaca agatggcatt gccccctaaa
     9661 gcgacaacta cttttcgttt ggccatttca ttcgtccttt cttcagttct accgaatttt
     9721 ctagataaca aaacgagcca gcgttttgtg attttccctc aatgctgact cgttttttcg
     9781 tgagatgaat gtggttatgc ttaaacgcga gggataaaca agttacctaa tgttgctgcc
     9841 atgatcgctt tgattgagtg catacgattt tctgcttggt caaattgacg agcatatttg
     9901 ctgcggaaga cttcatctgt tacttccatt tcagtgatgc caaagcgttc tttcatttgt
     9961 tcaccgtaaa cagtgtttgt atcatggaaa gctggcaagc agtgcaagaa gatcaaacga
    10021 tctgtgttgt gtgttttttc taccatttcc atattgattt ggtaaggttt caacaatttg
    10081 atacgttctt cgaatttatc ttcttcaccc attgataccc atacatcaga ataaaggacg
    10141 tctgctccgt ctacaccttt atcaacatcg tcggtaatca tcaattgtgc accggatttt
    10201 tcagcaaagc cttctgccat tttgacgatt tcttcttcag gttgtaattc ttttggtgca
    10261 acgatacgca tattcgctcc taaaattgca cctgtgacta ataaagagtt agccatattg
    10321 tttcgaccat ctccgcagta agcaacagtg ataccttcta ctgttccaaa gttttcttgg
    10381 atagttaaaa agtcagcgat catttgtgtt ggatgccatt catcagtcaa gccattccaa
    10441 actggaacac cagagaattc tgctagttcc tctaccattt tttgactgaa tccacggaat
    10501 tcgattccgt caaacatacg tcctagtact ttagctgtat cttctgtgga ttctttttta
    10561 cctaattgga tatcatttgc acctagatat tcaggatgtg cacctagatc gatcgctgca
    10621 gtagtaaatg cagaacgagt acgtgtagat gttttttcaa ataaaagcgc aatatttttt
    10681 ccttctagat agtgatgtgg gataccacgt tttttcaagt ctttcaagtg ttctgaaaaa
    10741 tcgatcaaat attgtaattc ttcttttgta aagtcttttt ctgctaataa gcttcttcct
    10801 tggaatactg attctttcat attaaacatt ctcctttaga ttgtttttat ttaagattaa
    10861 agaggaaatc ccgacggcag ctgacagtaa gactgccgtc aggaaacaaa ttacttcaag
    10921 tcttcacgga caagtggttg gctcatgcag cgtggaccac cacgacctcg tgacaattca
    10981 cttgaattga tttctaacac tttgatgcca tagctacgaa gcaattcgtt cgatacataa
    11041 tttcggttat aagtgactac aacacctgga gcgattgcca atgtgtttga tccatcattc
    11101 cattgttctc gaggtgcaac gatctcatct ccattaccag ttgggatcag tacaagatca
    11161 tctaatccaa gagcagcttt catcgtttcg tgtaagttat ctgaatgagt aatcttgata
    11221 tcatcaccat ctggttcgat tgtaaaggca tccatcttac cgtctttact ttgaattgct
    11281 ggatggatag tgaatttatc gtgatctacc attgtaaata cggtatccaa atgcatcatt
    11341 gcacggttgt tcggaatttt gattgccaac actttttcaa atcctgaatt ttttgcgaat
    11401 aggtggcgtg ctaatttttc taaagctttc gcattagttc gttgagaaat cccaacagct
    11461 actactttat cgcttaagat caattcgtct ccgccttcga tatgatctgg attttcacga
    11521 tccaaccata cttcgattcc tttatttgca aatcttggat gatgtttcaa aatatattct
    11581 gtaaacatcg attcacgacg acgtgcttca aaagtcatct tattgactgt catcccattt
    11641 cccattgatg cggaagggtc gcgtgtaaag tacaagtttg gcattgggtc catgtaaaat
    11701 ggatagtcat cgtctgctga cagatcatat agactgctag aacgtacttc gatatctttt
    11761 gtacgaaccc cagccatgat tttatctacc atttcttgcg tttccattga tagaaggaac
    11821 tcatgaagac cctctcttac agcattcgat gcaatatgag attcatccaa cattttattc
    11881 aagaattgtt ctttgacatt gcctgcgtca atcgcttctg ccgctaattt ttccaagtaa
    11941 agagtctcga cgccttcatt ttgcaatgtc ttcgcaaagt tgtcatgttc ttcttgagca
    12001 atcggaagat atggaatatc atcgaacaac agacgatcca taatatctgg tgtcaaattt
    12061 tccacttctt gtccaggccg tttcagtaaa actgtcttta atttccctat ttcagagaaa
    12121 acgtgaatag gtttatccat gttgtgttgc ctccttcttt ttgattacat gtataggata
    12181 tcctcctttt gtaatcactt tcataatttt gtctcattca aaatgagaca ttcctcacat
    12241 taatattcga taattaaata attaaacgtt tttctatttt taagcgtaat ttattcattt
    12301 tttattctgt atacactttc aaaaaaatat ttattcattg aaaaaatttt tttgaataaa
    12361 ttaaaaaaat aaattatatt atcgttgtta gcgtttacta tatgtattat tgttgttttt
    12421 tatacacaaa tcattcgctt caaaacaaat tattcaatac cattgtatat tttttacata
    12481 ataacaaatt atatttgtaa agtattaaaa cttgtttcta atgttggtat gttaaaactt
    12541 tacaaattct ttaaaaaaag tgacaataaa tatagtgaac aataaggaga ggacttttta
    12601 atgcgtgtta ataaaatcga ttttcacttt tcaaaactca gatatcaacc tgattttgaa
    12661 catttctcgg atgaagagtt ccaacagatc aaggaacata ctgttcttcg ttcttataaa
    12721 aaaggacaga tccttttcga cgatggtgat cccagacaac ggttgtatat cttgaccaaa
    12781 ggactcgttc gtttagaacg ttatgatgaa agtgcaactt attactacta tgactatgtg
    12841 aatacaaata acctttttcc tatgtcagga atgtttggag aagagaccta cacttataca
    12901 gctcaagcga tgactgatat tgaaacattc taccttcctg tttcctacta tgaaaaatta
    12961 gcacgaaaaa atcccgaaca gttgatctat atgatacaaa aaatttctaa agtagttgaa
    13021 atacatgaat tgcgtatcca aatcggattg acctctagcg cctttgaccg ggtaaaacaa
    13081 aatttattca ttttgaaaga agaattgggc gtaccaacaa aagatggtca tatcaccatt
    13141 ccttatccga tcaccttaaa agaattagca gtgaatagcg gcacgacacg tgaaactgct
    13201 ggacaagtaa tcaaacaact acgtgattcc gggctgttag attatgacaa aaagcgtttt
    13261 actttctgta agacagctac tactccagct atgagagaat aacgcgaaca aaaataagca
    13321 gtgaccctga taaatatcag ggtcactgct tattttcctc cctaaaactt ctgaaagatc
    13381 cggcagtttt agatcactgg acaagactca aagattttct atgtgtgttt cagttatgta
    13441 atattcactg tttgcaaaaa atactgttag attaactaga tgaagcgtct tgtcctcatc
    13501 cgatctagat tattcgatat tcctcgacaa taaacgatta ctcagtgagg gcaatcagag
    13561 gaacggataa tgataaataa gctgtaaaaa atagcaaaat aacaataatg attaaaagta
    13621 tgtaaaaaat agggctttga caaaaacgtg tcacagccct atttcgatta aacggtgtgt
    13681 acctgtcaac tcttcggtca caagtcataa tgttcataaa catgaggagc tgttttttga
    13741 aattgttcct tgtgaatcag agttaaacga caggcttacg aactcttgat taaacggcgt
    13801 tcaaaagctt gcatacgcgg taataagaac agccaggtca aaaacatgag aagccgtttt
    13861 tcctgggctg ttcttattac ttgatgcagg gcagcttttt cacaacctct ttattcagat
    13921 aaaaccaagc ttggatcagc attcaactga tagctagcaa aatttctttt ttgcatttcc
    13981 acatgtgctg ctgctccaat cattgcagca ttatctccac aaagtcgaag agggggaatc
    14041 actagttcta cctcagggag tttagttgcc aaagcatcct gcaatccttc acgcaaccct
    14101 tgattggccg ctacacctcc agctataatc agttgcttga ctggataatt ttgacaagct
    14161 cgaagtgttt tagtaatcaa tacatcgatc acacttgctt gaaagctagc tgctaaatca
    14221 tttttgtcta gatcttctcc acgctgttgt gcattatgca ccaaattgat aaatgcactt
    14281 tttaatccgc taaaactgaa atcataatta tcttcatgga tcatcgctcg cggaaaatgg
    14341 taattatctt ttccctgatg agctagctga tcgatttctt ttccgcttgg gtaagaaaga
    14401 cctaatactc ttccaacttt gtcataagct tctcctgctg cgtcatctct tgtctcccca
    14461 atgatttcat atgatccatc ttcttgcata tagactaatt ctgtatgtcc tccgctaaca
    14521 agaagtgcca tcaatggaaa ctggaatggt ttaaccagac gggctgcata gatatgccct
    14581 gccatatggt ttacaggaat aagcggcaat tggtgtgccc aagcaaaagc cttagctgca
    14641 gaaataccaa tcagcaacga gccgacaagt cctggtccat aagtgacagc gactgccgat
    14701 aaatcttctg ccgacacacc agcttctacc agtgcatctt ccaagcataa ggtgatttgt
    14761 tctacgtgat ggcggctagc tacttcaggt actacgccac caaaacgttt atgactgttt
    14821 atttgagaag caacgatgtt agataagatc tctgttccat ttctaacgac cgctacactc
    14881 gtttcatcac aacttgattc aatcgccaga atcaattctt cattcatttc atcgtctccg
    14941 tttttaactt tctgctcata atgatcgcat cttccgtcgg attgcgataa tatgatttcc
    15001 gtttacctaa tatacgaaac ttttctgatt cataaagttt tcttgctgct tcattagata
    15061 gacgtacttc taaaaaaaca tgcagcgaat cttttatttg ttccgtaatc agtaattgta
    15121 acaaatgccg tgcatgccct tttccttgtt ctgaaactgc aacagcaata tttgtgatct
    15181 cgacttcatc tattactttc gagtatccaa taaagccaca gatctggtta tcttcagcta
    15241 aaagcagata atcagagtga ggctgttgga tgtctgccaa aaactgcatt ttcgtccaag
    15301 gtgaaccatg tggataagca ttttcgctaa tcatccatac gcattctgcc aagtacgctt
    15361 catcaaaatc tttttttctg caaatcaact aatctcactc attttctaaa agttttatca
    15421 tatccaacgc atcttctttt gtttcagtgt aatatctttt tttgatcgtt gttgcttgaa
    15481 accccaattt ccgataaagt ctttgtgcat cttgattact catacgcact tctaatgaca
    15541 tcgtctcaca gcgattcatt atagcaaagt tctcgatttc gtcaataagc agcgaaccga
    15601 ttcgtttacg ctgatatgcc ggtcgaacgg caatattcgt gatatggcaa tctaaaccga
    15661 acgctcttga accgataaaa ccaatcattc ttccattatc aaagatacct agatatagat
    15721 gaggaagcgg tgacttcaat tctgatataa aggcactttt tgtccatggc aattcgccat
    15781 tatagacttc tcgttcgaca tccagcagct ctttgatatc ttctgtagtc aattctctta
    15841 gtacgtaacg acgatcgatt tgttcgactg ttttttctgt ataaatcatt ttatcttgaa
    15901 aaaagcttct ggcatacgct ctaaattttt tcaacataac tttcgtctcc aggtgtgtgc
    15961 gtctccaacc atttttcttc tgcttctact cgttttaaat agcgaggaag aaaagcttgt
    16021 ttctctgcaa ctggttcaac taaagcacct aattgagcca cagttacacc acttggaata
    16081 tcccatgctg gaactgtatt aatcatcgca ctaggcaata tttcctttat ttcagagaag
    16141 aatttgtgac aatcactccc gacgaaataa atagcttcat tcagcttttg tagttgtgtg
    16201 aacaaatcag aagcagaaat atgtacatct tcaagtacag tttctaatct attttctttc
    16261 cagcggtatg ccccagcgta tacatttttt cttcgagcat caaacatggg cacaataata
    16321 ttatccacac cgatgcaatt agccgcgatg gttttcagac tagatactcc tactagctct
    16381 ttatctaatg tataagcaat cgtttttgct gtcgttacac ctatacgaag ccctgtataa
    16441 gaaccgggac catcagaaac cgcgattcgg tcaatgtctt ttggacttat ttgaagatct
    16501 gcaaacaatt ggtcgattgc aggcatcagt gttacactgt ggttgcgttt gatatttgtt
    16561 tgtatttgtc caagaatttg ttcgtcttct accacaccga tcgccaaagt ttggtttgca
    16621 gtatctattc ctaatgtaat catatatttg atcctttctg ctatgacatt ctcgccttcc
    16681 attgtagcat acttttttat tctgaggatg aaaataccaa aggcaaaact agtacaataa
    16741 tacatgatta tctgctggcg ggcaaatttt gccccttcct gaaacacaaa aaagctgcgg
    16801 tatcactcca ttttcccaca gcttttccat cttttatttc gttgattctc gaataatcaa
    16861 ctctgtttcc acaataatct ttcttgaaac cggtgctttg gaattactta attgaagaat
    16921 cgtctccact gctagctctc ccatccattc ggtataaact tttacagtag aaagcgaggg
    16981 cgttacatat ttcgctacac tgacatcatt gaagcccatc acagaaatat cttctggtac
    17041 cactaaacct ttttcttgaa tcgctttcag tgcgccaatc gctaatgcat cattagctgc
    17101 aaaaagcgca tcaggaacat gcggattcgt ttttaaatac tgcttcactg cttgatatcc
    17161 tgactcgaca gaaaaatctg cttcgataat tggaccttcg tcgtagcctt tttctgccaa
    17221 aacttgttga aatgccataa ttctgggatc ttttagccgc tgatggtttt tcttcgtata
    17281 ttctgttcca gcaagcatag cgatatgttg cgctttatgg gagacaaagt gttcaatgac
    17341 tttttgaaca cttgacttaa agtcgacaac tagagagtcg attccttgag aagtgccgtc
    17401 agaatctacc aaaagcaagg cattttggga tcctttcatt tctaataact gagcttcgtc
    17461 gaattttcct agtgcgatcg ttccatctgc cggaagatca ctaatggaat cccacgtttc
    17521 tttcaataaa gtaacgtttg cttcttctgc ctttttttcg attcctaggc gaatagataa
    17581 ataataaaga tcttcaagct cttccgtatc gtcgtaccac tggatcaggc gaagcgtttg
    17641 cttagtattt gctgcatttt tacgatgttt cgtataattt aagcgttctg ctgcttcaaa
    17701 aattttttgc tttgtggcta agccaacgga aagatcagga tcatagttga gaactcttga
    17761 aacagtagca ggagaaactc ctgccaactg cgcaatgtct ttaattgttg ccatttgtct
    17821 ctcctccttt tttacgttta taaaatcgca gtaaatcgtt caaacgctgc ctgtcctttt
    17881 tcatctcgct tgaatactcc agcgtcttcc agtacacgtg caaaaacctg acctacagat
    17941 ttttgtacga catcggtgac cgtatctttc gtcaaatcag gatgttcttt ttttaattgt
    18001 tctgcccacg gacgatgata ttcagccatc tggttttctt ctcctaataa gaaatgctct
    18061 acttctacta gttctggttt caaacgaggt ggtaaaacag caagccccat tacttcgatc
    18121 aacccaatgt tctccttttt gatatgttgg acatctttat gtggatgaaa aatcccatca
    18181 ggatgttctt ctgaaacatt gttgtctcga aggacaaggt ccaactcaaa gtaattgtcc
    18241 cttcttcgtg caattggcgt aatcgtatgg tgtggtgtac catctgctga aaaagctctg
    18301 atagatactg tttcatccga atatgctttc catttttcca atactgagtt agctgcttca
    18361 ataagcaagt ttttctctgt tgattgcaaa cggatcacag acatcggcca tttcacgact
    18421 cctgcgatga cttgcggata atcttctagt ttgataagtt tttctatcgg tgcttttgcc
    18481 ataggaaatt catgacgtcc tgcctgataa tgatcatgag aaagaatcga tcctccaaca
    18541 attggtaagt cagcattcga accaacaaag taatgaggca agacttcagt aatccgaagc
    18601 agtctagcaa atgtttcctt tgtgattttc atcgggcggt gttgttctga taaaatgatc
    18661 gaatgttcat tgtaataagc ataaggggaa tattggaatc cccagctttc accgtctaga
    18721 ttcattcgaa taatccggtg attggtgcgg gctggatagt tcaagcgacc tctatatcct
    18781 tcgttttcca tgcaaagcat gcaggtagga tagtctactt ttaccgcctc gcgttctgct
    18841 gcgatttgtt ttggatcttt ttctggctta gataaattga ttgtgatttc cagttcacca
    18901 tactccgact ctgccggaaa tttgatgttt tttgcgatgg ctcttgtttt gatgtagtca
    18961 tttttcttac ttaaattaaa gaaatactca gttgcttcct ctgggctttt cgaatagtgc
    19021 tgtgcaaaga atgcattgac gactgaaggt ggcggtgtga gaaaatccat taattgcgct
    19081 tcaaaaatct cttgttctgc tggcaattct gaaagaacac cattttctct tgccttagcg
    19141 acaagctgat ccaataagtc tacagattct tccttaactg gtcttacttc aatgctttct
    19201 agagcatctt ctcctaccat ccctaaaaga cgattctgta aatataagcg gtccatttcc
    19261 atccatccgc cagcttcgat cgcaagtgtg gcaaaatcac aaatcgtttg actgattgac
    19321 atatctcatt cccctattct tcataaccat ttggatggct gacatgccaa tcccatgctg
    19381 ttttgataat cgctttgata tctgtgtatt caggtttcca gcccagaatc tctctcgctt
    19441 tttcacttga agcgactaat cggctaggat ctccagctct tcttggtgct atttctgctg
    19501 gaatttcttt tcctgtcact tctctagctg cttctagcat ttccttgact gagtatcctt
    19561 tgctgctgcc taaattgaag aagttgcttt catttccttc tttcaagtat tccaaagcta
    19621 aaatatgtgc agcaatcaaa tcttctactt gaacataatc tctgatacat gttccatctg
    19681 gtgtatcata atcgtctcca taaacagcca aggcttttct ttgaccaaga gctacttgta
    19741 aaatgattgg gacaagatgc gtttctggtg tatgatcttc tccgatagat gcatctgctt
    19801 ttgctccggc tacattgaag tagcgcaaag cgacatagcg catgccatat gcttggtcac
    19861 accacttcat cattttttcc atcatcaatt tactttcacc atacggattt ttaggattag
    19921 ctggtgtatc ttctgtgatt ggagactctt tcggctctcc ataagttgct gcagtagaag
    19981 agaatacgat tttattcacg ttgaactcgt gcatgacttc aagtaagatt tgcataccgt
    20041 atacgttgtt gttgaaatac atcaatggtt tttcgacaga ttctcctact aaagagcttg
    20101 cagcaaaatg gattactcct tcaatcggtt ccttttcaaa tacggaacgt agaaattctt
    20161 tatcccggat gtctccttca taaaaatgag catctggatg tactgcttgt ttgtgacctg
    20221 tgagcaaatt atctaccaca gctacttgat accccttttg aactagctgg tctacagcgt
    20281 gcgaaccgat ataaccggct ccgcctagta ctaaaattgt cataaaaaac actcctttga
    20341 ttagtaaaat tgtgtttgtt gattctatat aatttaaaaa acgaagttta cttttatggt
    20401 gaaaacaaac aaagtaaaat ttcgtaaatt catatggtaa atttataata aaacatttag
    20461 taaacatttt caaggatttt ttgcaaaggt ttacaaacaa acgtaaaact agcctttttt
    20521 tctcttttgt tccataatag atataacaaa taataaatga ggtggattca atgaaaaaat
    20581 ttgtatctgg aatattagta ggaagtctgg caacagccgc tgccgttgct ggtttggttg
    20641 cttctgtgaa aaaaacagtg atcgatccaa ttgacgaaaa agaagcaatg atcgaagaaa
    20701 accgtaaaaa agcaatgcgt aaacgcgttt ctcgttaata attatttaaa aatacgcatg
    20761 aagactttct aaaaaacaga taagtcatca tgcgtatttt tatttgtcag tcaatataag
    20821 ttgtgctatt ttatctgcct gtctcagatt ccatggatct gtataaggtc tagctactgc
    20881 tgcagttagc caatccacac cttcaacagg tattccatag caataaaagt cagactggat
    20941 ttcccctgaa gcatcaatca cgcgattcgt acctcgctca acatctatag cttctgaatg
    21001 ataacttcct gtattatctg aaaatgaaaa agggcgaaca agtttgtttt ccttcaaatt
    21061 ttttatgaca ggattacttg aacgagaaaa gcttgtttgt ggcaatcgag cttcaatcaa
    21121 atagcgactg ctgatttctt tatcttgtag agaaataaca tagcggttgt gcttttgctg
    21181 aatatcaaat ggcggttcga tcaaatgaaa aatacccgca tctatcagtg ctgctaattc
    21241 tttcgtccga atgattggcg gaccgatcgt taaaaagcta tttagatgag taaaccatcc
    21301 ccatagtatt tctttgtatt ccttagcaga aaaaacgtgc cattcaatag cctgccggat
    21361 tggatcacgc cagtctttta atgcatcaaa tgttgaagca aatgctcctg tgcaattgcc
    21421 tttttccgct tcttttatct gcccttcaat aaatattcgg ctagcttctg aaaagggctc
    21481 attctgatag gcaagaggag tttctaaata cgaccaatcc catctataag ggattagtgc
    21541 tggatgcttt ccgagacact cctctgaaga gagggagaga aaatcatgct caaaattttt
    21601 ctttggaatc ggcaagtgat attcttcgat gattttcttg taataaaaca actcaacgtc
    21661 ttttttcaga tagtcaaaaa atgtttcgcc agtcaaaaat cccgactgat gccattgctc
    21721 caggttttca tttgttagta accgtggcca tgccattgct ccgccttgct tttgatttct
    21781 tcctcgaggg taataaggga gcccccttct tgatccactg tatacaatcg gttccttgcc
    21841 tgatggatga tagaccagtt ttcccttttc gttctcgaag cgccctcctc ttgatactgt
    21901 aaacaatccg acataatcaa aaaaacttaa gcctagacct cttaaaaaga cattttcttt
    21961 aggcggtatc ttcgaaagat ctacatctgc aggattagaa ggaagctgat acagtaaaac
    22021 atttttcttt gcgtagtcta cccacactct ttcttcttct gtctcatcat tttcccagtg
    22081 accgcttgct aaaacaagct gatcgataga atagctttgc tgatctgtct gtaaaagata
    22141 accatctttt cttttgctta ctttttttac taaagaataa acaaactgaa tagaagctgg
    22201 aaattcttct tgcaactttg agaaaaacca gcgttgatag agtccgtata aacatcgagt
    22261 agattgctga tctttttcca gacgattgat ttcttctata attagttgct tatttttggt
    22321 taccgtctgt tcgatataat ctgtagcagg tcctttactc cattgaaaca agttgggtcc
    22381 ctgtgttacc aatcctccac tggacaatgt ttcatctgta aaaagcgtca cttgttgaga
    22441 aacagaattc attaataact ccggtggctg attcaaccgc caaactcgac ctccaggacc
    22501 attgggatcg aaaagaaaaa gttcaagaga atgtctgtcc tgattattat ggagaatcct
    22561 ttctgctaca cttaatcctc taggtccggc accaatgatc cctattttca tttgcatgcc
    22621 tccatttcga taaatttttt caataaaaca gcatggttct gatgttcatt ttttgcacca
    22681 taaacaaaag taatgactgg atgttctttc ataagttgac tgagtttaaa aatagcttgc
    22741 ttcttttctt cttcgaaaat caattcttgc tggtatttct ttgcaaatga agcaaatcgt
    22801 tctggtacat ggtcaaaagt tttgcgtgct tcattactag gtgcaatttc tttcaaccac
    22861 agatctaact gcgctttttc ttttgaaatt cctcgtggcc agaatctatc cacgagtatt
    22921 ctatagccat cctctttttc agcatcaagg taaacacgtt ttaatttgat catagttgtt
    22981 tccttctttc taccttttcg cttagcttat atatgtagat aatagcacaa aataaaaaaa
    23041 atgaacggca caactatcca ttgcgccgtt catgtgatct tggtcaaaat ctaatgattg
    23101 attcggtttt taaagctgtc atacaatcat ctgttttata cttttttact tttgattttt
    23161 ccagaccatc cgtcatatcc acccttaagt aaataaatct cttgataacc tgctttacgt
    23221 aatttatttg ctgtacggat gctcaaactt ttcttttgat cgtaaatata gacaggctgg
    23281 tcttttcgaa tagatcctaa tgaatctttc aaaacagtgt aagggatgtt tcttgcacct
    23341 aaaatatgcc cagcatcaaa cacatctttt tcgcgaacat cgattacttg tgcttttctc
    23401 attccttctc gaaattcttc ttctgtcaaa gtcgttgctg aacgtttggc cattactcgt
    23461 agatagactt cccaaaggat gattgcaagc acaatcaata gcaaaatgat attaattacc
    23521 cataaaacca tgtaatgcct ccgttttttt aagcaaattt caaggctaat gaggcagcac
    23581 caatgacacc agcttcatta ccaagctctg ctaatttgat ttttgttgat tctcttactt
    23641 gcgggaaagt aaattcttta aaatatttct ctacacggct acgtaaaaat tctcctgctg
    23701 ccgatactcc tccacctaac acgatacttg acggatttaa tgtattcccc aagtttccgc
    23761 aagctaaacc taagtagaag catacgcgat caacaaccat caatgcaaac ggatcgtctt
    23821 cttgagccat ttcaaagata tctttacttg ttacttcttc tccgttgtct agcattgctt
    23881 tcagttttga atcccctgcg tattcttctg ccaagaaacg acctaggcgt accacacctg
    23941 tagcgctaga tacagtttct aaacatccgc gtttaccgca agtacattcg aacccttcag
    24001 gatccacagt gatatgtccg atttctcctc cagctccgct cacgccgtga atcaaatttc
    24061 cgccagcaac gatacctccg ccaacacctg ttcctagagt aacgaataca acgtctggat
    24121 cgttttctcc agcacctttc catcgttcac ctaaagcagc aacattcgcg tcattatcga
    24181 tagcgaattt gattcctgtt cctgcctcga tcagtttttt cacaaattga acttctgtcc
    24241 agtttaagtt atacgcacca ataaccgttc cagcttcgct gtccacgctt cctggggtac
    24301 ccatgccgat tccgataaag tcttcggctt tcatattata taaattcaaa cgatgattga
    24361 ttgattcaat gatttcagga acgatatgct taccatcatc caaaatattg gtatcgatgc
    24421 tccatttttg ctgaatctct ccttctggtg ttaaaattgc aaattttgct gttgttccac
    24481 ctaaatcaat cccaataatc ttcttgtcca ttacaaattt cctttctttc ggctttcttc
    24541 aattcggtgc tctcttttta atatgcgcca cgctgtcatg tatgtatcat gatcaatcaa
    24601 acggctatca tacagattac gcaattcgat agtcattaat tcaatgtcat agatgcgtgc
    24661 acccacatag ataaagatgc caaatttttt gaacagctgc tgtacatcat ataagctctc
    24721 catctttaag cacttccttc atattataca agtaaaccat atttttttaa acccagtaaa
    24781 atacatatta caaaaagaaa tacaaaaact agtgtagaaa gaatcctttg gtgtatcgaa
    24841 tagcttgtct gttgtttcgg tagacccaaa acattcccta acactaatcc gccaattagc
    24901 ccaccgacat gtccccaaac atctacagag gtatccagaa gaccaaaaac aaatgtcaac
    24961 acaataaata aaagaaaatg tctgactagc tgctggatcg ctgggttatg tttaaaatga
    25021 aaccctaaga taaacaacgc accgaacaaa ccgaatatcg aagtacttgc accaccagac
    25081 agaacattcg cttcgttaaa agcaaagctt gctgtatttc ccattatccc gctgaacata
    25141 taaatcaaga aaaaacgcca atggccatag attgcctcga tttgctgccc cataaaatac
    25201 agtatcagtg agttcattac gaaatgcatc agtccaaaat ggatgaagat tggtgtcact
    25261 aaacgccacc attcattgaa gtgaacaaga taaggaccat acattccggc ataataaggg
    25321 atctcaagtc gcggaaataa ttccatcatg aggaagaccg ctgtctgtat ccctaaaaaa
    25381 gcataggtcc ataacggtcg tcttaaccat gcacgcaatt ttatttgctg ttgataattc
    25441 atgaaaacct cccatttcat tttagtcaat aaacaattgt tggatcttct gatcaaagct
    25501 ctccggttgc cattgttcat tcaattgttc acgaaaaaca aggctacatg tttttttatg
    25561 aaaattattt aaataccggt cgtaataacc accgccaaaa ccgattcgat aaccggctct
    25621 attgtagata atacctggta caatgaggag atcgatcatc tccggcaaat agagcttctc
    25681 tgattgtggc tcaagaacac caaaactcga acgtacaaga acggactgtt catccatttc
    25741 ataaaacgcc atctgacgtt tcggcaaagt tttaggtaca actattttct tttgttcttt
    25801 ttctgctcgt tggataaccg gctgtgtatc cagttcaaat tcattcgata aagtcgtccc
    25861 tatcactttt gctgacttcc agtactcgct ggcgaatagc tgtttataga ttcgctgttc
    25921 tttttccttt ttcttgccac ttttggccag atttttcagc ttttcgattc ctttccggcg
    25981 taatcttact ttcaattggt ccaaaaactc acccttcctt ctctcataaa atggtatagg
    26041 aaaaaaagaa aaatagcaat cgaactttca aataaatgca taaatagaat aaaaagaaga
    26101 cctagaaatg attggccttc cttttttaat gaatttcaac tgttcagcgc gtgtttttgt
    26161 ctgataaaaa gtgcatacag aaaatatggc gcaccaaaaa gggcaatcaa aattcctgta
    26221 ggtacttccc cacttagtag aatcactcta gcaaccatat ctgcactaag cagaaaaatg
    26281 gaaccgaaca aaccgctcag aacaaaggtc cagttatttt ctttacgtac gactagcttc
    26341 gcagcatgag gagctagtag tcctacaaaa gataaactac ctgtcaccgc tacactaccg
    26401 cttgccaaag caacagctaa caacaaaagg attttttgac ttttagccac gttaaggcct
    26461 aatccttgcg cgcgttcttg accaaatgat agcaatacaa tcctctgtgc ataaagtcct
    26521 cctagcggaa ttaagataac cgcccatgga agcaatgccc aaacataagg ccagctcgca
    26581 ccccagattg atcccgctaa ccatgcattc acaaatccat aattttcctt agataattgg
    26641 atcgtgcata gcaatgttaa tgcagaaagg ccggcattaa cggcaatacc ggacaataag
    26701 attcgattca tacccaaaaa gccatttcga tcataggccg caagatagac acagcaagca
    26761 gctaaaacac cacctagaaa ggctacaact agcaatagaa acggcagcga atagtgcgaa
    26821 aagaaaccta aataaagcat cactaaaaat cctgctccgg cattaatgcc caatatacta
    26881 gaatctgcca attcatttct tgttactcct tgcaagatat aaccagaaac gccaagacaa
    26941 gctcctgcta ataaactgat cagtaatcga ggaactcgaa attctctaac aatcagcgcc
    27001 aaagaagatg attctttccc tatgaacgtg gcaaaaagct gatccaggta aataaaaggc
    27061 gtaccaatca ttaaactacc tatagacagg atgacaagta caaaaagcaa gaaatagaac
    27121 gtccaatata tttttttcac cgttgttccc tccttacttg tatcagtaaa aacggaacgc
    27181 caatcaatgc aatgactaat ccaaaaggtg tttcaaaagg gggattgatc atcctcgctg
    27241 taaaatccgc caacataacc aatccaccgc caactaaaaa agagacaggt agaacataac
    27301 gatagtccgt tccaaccatt ccgcgaacaa ctggcggaac caacagccca ataaatgaaa
    27361 caggtccgac taacgaaacg gcaatggctg ctaacactgc aactagacag aaaacaatca
    27421 accgcgttcg tttaggatga cttccaagag ctaatgcatg tgtttcactc aaatgaatca
    27481 aagatattgc ttttcctaat gaaaaagaaa ccaaaacagc aagtatatat aaaggaaaca
    27541 atactgctaa ttgtttccat gtgatattgg cagctccgcc tacaaaccaa aaagcaagat
    27601 cctgctgcag attaaagaat tgggtaagtg cttggctgat agcagtaaaa aaagaactaa
    27661 tagctacgcc agctaaaatc agctgtaaag gattcatgcc cattttcgaa aactgcaaaa
    27721 aaccaaatac gagcaaagtt acagcaaaag aacctgccaa tgacattaga aacacagaaa
    27781 aatcagaagc tttaggccaa aaagcaaaac taagggccat tgccaacgaa gcacccgcgt
    27841 tgattcctag taagcctgaa tctgctaaag gatttcttgt cactccttgc atcaatgcac
    27901 cgctcaatgc aaaacaactc cctacaagaa atgctcccgc cacacgaggc aaacgaatat
    27961 ttcgtatgat ttggtgactt tgttttgatc tatcaaaatc aaacaacgcc tgccaaaaat
    28021 ctgcttttcc cacagtcgct gcgccatttg aaagagcaac aaaaaaaata atcaaaagaa
    28081 caaaacagac caaaagcagg agtctatttt tcttcatagt cctcataatt gatcctcctg
    28141 ctcttttggc aacaaatcat aggttagaaa aactggttta tttgttcttg gaagcgtgac
    28201 aatcgttgca tcaatctcaa atattttttt catacactct tttgtgatca cttcttcagg
    28261 tgtaccttct gtgatcaact taccgttttt cattgctaat aaataatctg aaaaacgtga
    28321 agcatgatta atgtcatgaa tcgacatcaa gatcgttgtt tgtttcattt gattgatttc
    28381 agtcaataac tgtaggatct ctaattggtg tgccggatct aaaaatgttg tcggttcatc
    28441 caagatcaag atatctgttt cctgagcaag cgccatagcg atccagacac gctgggtttg
    28501 tccaccagac agcgttgcga tatcccgcat acgaaatcca gctagacctg tagcatccaa
    28561 cgcccactcg attgcttcat gatcttgcgt gtccatgcca ctgaacagtt tttgataagg
    28621 gtatcgtccg taagatacta cttcttctac tgtcatacct gtagggtgtt cactagtttg
    28681 tgctaataat gcaatttttt ttgcaagttc ttttgaactg tatgtagaga tatcagagtt
    28741 attgacaatg atctttcctg atttcacagg tagtatacgg gtaaaacttt tcaataaagt
    28801 agattttcca cttccatttg gcccaatcaa actagtgatt ttcccttcag gaatcgtaac
    28861 agacatgttt tcaatgattt ttttgttttc gtagccggct gcaatgtcag ctgctcttaa
    28921 tctcgtcatt tcacccatcc tttcgctgaa aatcattctc aattatgacg ctgtttcaac
    28981 atttcgtcaa gcgctacttt catatctata gccaaatgaa gcggttgaca gcgttcgaaa
    29041 tatcaggaat aataaccaat gagaaagatt ctcaattatg ttaggaggaa agaaatgaaa
    29101 ttaaaaacaa aagtattcac attatctagc atattgctgc tggctggagt actgagcgct
    29161 tgctccccct cttcagataa agaaacagct acaactgcca attcgacgac ttcatccaat
    29221 agtactcata cagtcacaga tacacttgga cataaagtag agattccaaa cgcgcccaaa
    29281 cggatcatcg gcagttactt agaagactat ctgattgcac taggggaaaa acctatcgcc
    29341 cagtggactg ttggcagtgg ttccattcaa gattatctgc aagatgattt aaaggatgtc
    29401 ccaacgattt cttatgacct tccttatgag aaagtgttaa gctttgagcc tgatttgctg
    29461 ttgatttctt cttccgctac tgtcgaaggc gggaaatacg aacaatatag caaaatcgcg
    29521 ccaacttatg ttgtaaaaaa cggaacagat gtcacatggg aagaacaact aaaagatgtc
    29581 ggcaaagctt tggcaaaaga aaaagaggca gaaaagatca tttccgatta tcaaaaatcc
    29641 atcaagaaaa ctcgagaaga actagcagat aaaatcgaga acaagacagc tgcagtgttg
    29701 tgggtgacca acaactcagc ctttatggtc agcaaaaatc ggtcaagtgg aagaatcgta
    29761 tacgacgatc tggaatttgg tgttcctgat ctagtggaag aggtctccaa aaaagccact
    29821 tctgactggt ctgctgtttc ctctgaaaag ctagctgaat tagatgctga ctacatcatc
    29881 cttgtgaaca gtgacaaaga tgctgccatg ttcaatgaac caagctggaa gaatcttaaa
    29941 gcagtgacag acaatcatgt actgcaattc ggacctgaat ctagttggct atataacgga
    30001 cctattgcca gtcaggaaat ggtcaatgat atcaaagaaa aactaaattg attttaacta
    30061 aaaaaagcat cttcacgatt agtcgtgata tgcttttttt cttattaaca aactagacgc
    30121 atagatttta ttcttctttt gaagcaaccc tattttttac tctttcccat ttttgaaaac
    30181 gatgggcata tagattttct tgatccgtta tcccctcata ctcctctata agggcgaagt
    30241 ctgaaaaatc aatattccca atatacgtat cgccttcaaa cgtgctatcg atcaatgttc
    30301 gccagatccg accagtgtaa ggaagaagtt cttgaaaaat ccgactacca cccgaaacat
    30361 agatatcttc tgagatcgtt tgactatacg acaaaagttc atcgatcgaa tgcattactt
    30421 ccgcattttc tttcgtgcga aaatttggct gcgttgtcaa cacgatgata tggcgataag
    30481 gaagtgaaag atcccccatt ccttcatagg tctttcttcc catcactaaa attcgatcca
    30541 ttgtatgttc gcgaaagaaa cgcatatcat ttggcaatcg ccatggtaac aaaccatttt
    30601 tgccgatcag accattttta tcttgtgccc acatggaaat aaacatatta tccgctcctt
    30661 atgattttag atgttttgag ataaaaaaag tctcaattct ttgaccagca aggaattgag
    30721 aactttaaaa acattatttt gtttcacggt gcaaagtaac tttgcgttcg cgtgggcaat
    30781 atttttgttt ttccaaacga tcaggattgt tacgtttgtt tttgcttgtt agatagttac
    30841 gttctttaca agaagtacac tctaaagtga tgtttacgcg catgtttttc cctcccattt
    30901 ttacaagaat cctctaagat gactctcaga cttgattatc ttaccatgat tttttctaga
    30961 ttgctagtgt ttttcacgat tttgttaagt aaaactactt gacgataaat acaacggttt
    31021 tacttctcaa acaaaatctt tttctttttg tataaatacc cttacacttg tttatataga
    31081 ttatgttttt taataaaggg ggatactaat atgccatgga acatgaagga ctttcctgca
    31141 tcaatgaaaa acttagataa attgacaaga aaaaaagcaa tcgacatcgc aaatgcatta
    31201 ttagatgaag ggtaccctga taaccgtgcg atcccaattg ccattgatca agcaaaaaaa
    31261 tggtatgaag atgctagtga atcagaaaaa cgaactttcg aaaaagaaaa aaatccaagc
    31321 aagacggatg aacacgatac gaatcctcgt gctggaaaac tgcttgattc agatgtgatc
    31381 gtagaatatg aggaagaaca atggatcgtg aaatctaaag gggcaaaaaa ggcaagcaac
    31441 cattttgata caaaaaaaga agcaatcgaa aaaggaaagc aagtagcaca aaacaaagaa
    31501 tcaactttgt tcatttataa aaaagatggg acaaaagaaa aagaaatcga ttattgaaca
    31561 tatgtaaagg ggttgtgacg aaaatcgtgt cacaaccccc ttatgttcga aacaatggtg
    31621 ttcctctgcc aactccgaac cataagtcat aatatctata aaacgggaag agctgttttt
    31681 tgaaattgtt tcttatcact cagtgttaaa cggtaggaga aaacctcttt tttattgata
    31741 tttgattttc atcaaacagt cacatagtcg attgcttctg cttgcggaat cgtttcatct
    31801 acaaagtaga ctttatacca tgtcaagaaa ctgaagattg tccagatttt tctttgctct
    31861 tctttacgtc cttcgtgatg gtcatctagc aacttcatga ttttttcttg atcaaaaaat
    31921 tcttttgcaa aatctgcttc gaacaatgct ttgacttgtt cgtagccgtg ttcttctttc
    31981 aaccaagctt tgattggcac agggaatcct aatttcacac gattcgacca tttttccgga
    32041 agatgtttgt tcgcagcttg tctgaaaata tcttttgtgt tgttttgatt caataaaaac
    32101 ttacttggta tttgttgagc caatttcatg acttcgatat ccaataaagg tactcggact
    32161 tccaaagaac ttgccataga aagtttatct gcctttaaca agatatcttt tggcatccat
    32221 tgatgaagat cgacatattg catcttattg acttcatctt tgattccttc tgttttctcg
    32281 taatgaacag tcatgatttc atccacagat ggtgctgttt gatattttgg tgttaacact
    32341 tctgatgctt ctgattcttc gaacactcga gcatgaccga taaaatattc ttttgcagga
    32401 gcaagtgatt catataaatg gatccgtcca tggaaatttt tcatttttcc gattttacgt
    32461 cctaaattat agcgtgttcc ttttggtaat tttttcaatc cttgagcaat cacacggatg
    32521 aattttgaat tcgtatggaa tccatacgtt tggtatcccg caaacagttc atccgcccct
    32581 tctccagatt ggactacccg cacactttgt gaagcaagat ttgctaaaaa gtacaaaggt
    32641 acgcaagaag gatttgaatc aggttcatct aagtgatact ggatcaaagg gaatgctttg
    32701 aacgacatgt ctccgtcgat cactgctgct gtattatcta agtccaatag ttcggttagt
    32761 tttctggctt caatcgcttc attataggtt ttatcatcaa acccgattga gaaagaatga
    32821 tctggtttca atacagaggt tacataactg gaatcaaccc cgctggataa gaaagaacca
    32881 acttctacat cactgaccgt atgtgcttca atagaagctt gaacggtttc gtcgattttt
    32941 tcgatccatt cttgtcggga atgcgtttct tttgtttcaa aatctgcatc ccaatattgc
    33001 tgaatgtcta tttttccatc tttatacgta taataatggc cttcaggcaa acgatagaca
    33061 tctttgaaga atgtttcgcc gtttaatgga gaatattgga aagtcatata aggtttcaac
    33121 gcttctttgt tcaattcttt gttaaaatca ggatgaggca gaaaactttt gatttctgaa
    33181 ccaaacataa atgttccgtt catttctgca taataatatg gtttgatccc aaagtggtct
    33241 cttgcaccga ataactcatt cttttcatta tcccaaatag caaaagcaaa cattccgcgg
    33301 atcttttgca ataattctgt tccccattct tcgtaaccat gcaaaaggac ttctgtatct
    33361 gcatgtgttt gaaaaacgtg gccagctgca atcaattctt ctctcaaagg ctggtaatta
    33421 tagatttcgc cattaaaaat aatgatcttt gtccgatctt cattgtaaat aggctgagta
    33481 ccgccctcta agtcaataat acttaatctt ctgaatccta aagcaacatg tttatcgata
    33541 tattctcctg aactattagg tccacggtga acgattcgat ccatcattgt attaataatt
    33601 gtttttttgt tgtccttgtc gttaacaaaa cctacaatac cgcacattta actttcacat
    33661 cctaatataa aattactgtt tatttcattc atatgcatct tatcatagaa taaatagcgg
    33721 acgaatattt tctctcttac aatttcgtca cgtgaaaaca aaagatgaaa gtttctgttt
    33781 ttacagaaaa taaagtccca atatctaatt taccatgttt tcttttttga ggctacctta
    33841 ttctcttcgt gttaaaaaaa tattagtgga tgctatttcc aaaaaaacca gcaaaaaaag
    33901 acacgaccta aagatcgtgt ctaattatga ctgtatcaga aaatatgata ccaaacggat
    33961 ctattcatta attaattgac atagtttatc tgttgctctt ttatgactgg ataactgacc
    34021 aattcatgac gatccaagtc ttctttattc atatttacag cagtaatttg actgtcttca
    34081 tacgtacgat aataataaat ccctttatca acgttacagc aagaagaata aatcgtatat
    34141 tcgtattttc tttctccagt atcgcatact cctttttgtt gctcgactga gcctagtata
    34201 tgaaaaaatt gactgatact ttcagattct gaatcacctg atgcagcatt cattttagta
    34261 aatgtggctt ttacaaatcg agaaacagaa gagagatctc caggtaagcc caatcctccc
    34321 atcccacgac tataaacatt caagctgatc tggtttgaaa aatgattttc tggtgttcca
    34381 tttgatagcg agcgataatt gttcagatta aataattgat aatcaaatgg cggattattt
    34441 gtcaacacac cgacaggatt atcatataaa tgaagtccat ctttcatact ttcaattact
    34501 atcgattttt ctttatcagc taataaccag tgtaaaggtg acaagggtag tttttcacta
    34561 aaatcgatat tgactagatt gatagtagcc aataattctt tagcttcgtc tatggttgag
    34621 cattgcccta gtatccatgg aataaactca aatggtgcaa cgttatcttt tccttcttgt
    34681 aattctttat aatcagcatt gccaggaaaa ttcagtcctg ccatactcaa ccctttttca
    34741 tttgtagcct cataatagag tggatagttg gataccccag ctgctattcc tatcattgca
    34801 taatgtttat ctaaattttt tacctttcta aaatcgaaac gataatttct tggagtaata
    34861 gtgaccactt cattataaga catctcataa tcaaaattcc ttccaaaata atggtctttc
    34921 gttgcataag tgattgcggt acacatcgtt tcccgtccta aaacaaatcg tttttacact
    34981 tttatcttac atctagtatt ttttttatca aaaaaaggcc aaagaagatt gatttactag
    35041 catttataaa aaatagtact cagggggaat caaaaaatat tgtaggttaa aagtacaaca
    35101 ataaggggct gtgacaaaag tcttgtcaca gccccttatt ccgaacaaac ggtgttcaaa
    35161 agcttgcatc tgcggtaata agcccaatca aacgaaaaaa taggaaaagc tatttttgtt
    35221 tggccgttct tattacttga tgcaggacag cttcttcaca acctctaatc tttgatataa
    35281 ggaaggtaca ggatttgaac ctgcgcgccg gtattagccg gttcgccgga tttcgagtcc
    35341 ggtgcattac cactctgcca accttccgta agtactattt ttaaactttt ttcacgaaat
    35401 gtcaagccta tttctaatag ataaataaca gaaatcgctt tttttagcaa aaaagtccat
    35461 tgacagtttg cagccaacgg acttaccgat caaattcata ctgatagaac actatctgat
    35521 tatttcagga ttatctaatg ctaaaatcga gtcaattgtc cgtttgatca gtgcaatgat
    35581 ttgttcttct gttggatgca tgatgtttga tgacatcaat gacgctaagc cagtcactgc
    35641 tacccatgta ccagtatgca gagcatcgac atattcatcc gataattgat tgtatctttc
    35701 atcttcttta actatttcac ggaaataatt gtatgaaaaa tcatgcattt tctttccgtc
    35761 cccatgttca tcaatgtaca atgccatgta aagactatga tgcttttttg caaagtagat
    35821 atagttcaaa ccgagatcaa tgattttatc accagtacgt tcaataggga aaacatcttc
    35881 ttttagttgt tcaaagatag aatccagcaa cgtatttttt aaatcttcca tgtttttgaa
    35941 ttccagataa atcggctgtg tcgaaatccc catcttttta gcaatatttc tcgcagtaaa
    36001 tcctttaaac ccttcctttg caacaacatc ataagcagct tttagaattt gatccttggt
    36061 atagactttt cttctcatta aaactccccc acttctttac tgcagtatat gttgttttat
    36121 tgtaccctat ttttagcatt ttttgcaaac attttactca aaacgttata ttttaaattt
    36181 tttttcagtc ttctttaact tttttttgca aaattaaaaa aatttggtta aattcaatgg
    36241 gttcccttac atttttagtt ttgacctaaa tgatagttgt ccaaatcttt catttcaagt
    36301 tatagttaaa gaaaatgaaa aagaaggtgt gtaatggaaa acgaaactga cgttatttat
    36361 attcatcctc aaaaacgaat cgtttcacag aaaagaaagt atttttatct tggttttaca
    36421 ggtgtttttt ttctttttat tggcttgctt tctaatactc ctactgataa ttggagtgga
    36481 ttgctaacta ttcttacctc gccaagcaat cttttgacag attattttgc tttaggcggt
    36541 ttcggaagcg cattcataaa tgtagggatt ttgaccttac tttctgtgct tttagcttat
    36601 cggcacaagg tgattttaaa cggtccctta tttgcttcga ttctaacagt taccggtttc
    36661 tctttttttg gcaaaaacct ttataattct atctcaatca ttttaggtgt gtatctatac
    36721 gctgtatttg tcaataaacc tttttctcag tacatcatga tcggactgtt tggtagcgca
    36781 ttatcaccgg tcgttagtta tatcactttt ggtatgcgtt ttcctttact gataggtatt
    36841 ttattgggga atttagctgg catagcaatt ggtctacttc ttccgccctt agctgctcaa
    36901 actttagttt tccatcgtgg attcacactt tataatattg gattcacctc tgggttgatt
    36961 gcgatgactt ttactgctgt tttgaggtta ttcagctatt caatcgtcga aaatacattg
    37021 gttttcaatg aatatcactt tcctctcatt tggattattt ttggcttttt ttcgctgaca
    37081 gtcggaattg gtttctatta taattccttt cggcttttgg ggattcgaga aattttcgat
    37141 tcatctggaa aattgacaac tgatttcatt gctaattctg gtattggtgc tactttgatc
    37201 aacataggct tagttggtct gatgctgtct tcttatgttt tgctggttgg cggtcagtta
    37261 aatggacctg tcatcggtgc tattttatct gcggtgggtt tcagtgcttt tggttgtcat
    37321 ttaaaaaaca gttttccgat actagtcgga atatttattg cttctttgtt tggaactttt
    37381 catgagatca ccagtactgg catgcttgtt gcagctgtgt ttgggacagg tctcgcgccc
    37441 ataagcggtt tttacggcag tttttacggt gtaatagctg gtgtactaca tattgctctt
    37501 gtccataacg tcagcacttt gcacggagga ctaaatctat ataacagtgg tttttcaact
    37561 ggtttcgttg caggtatcct tgtaccgata ctagataact ttaccgctgt cagaaaggaa
    37621 aaaaagacac ttggaaaaag aattatcaaa aagaatcatc gatgagcttc ttacttattt
    37681 atattcccat gaaataactg aaatacgtat tggagtagaa tttgctgagg aagggctttt
    37741 catagagata cagggtacgg cagaaactca gccagaagat ttagatgtac ttgctgattt
    37801 gctgaacaat cctcgggacc ctagtatgga aatctattat caagaactat taggtaatcc
    37861 ccgacatgat cgggaagatt atcatctgtt aggtagtttg attgatgacg tggaaatcat
    37921 gtatgcccag ccgattatca atattaagat ctttcgacgt gcttctcatt cctattatta
    37981 accctatttt ctatttataa aagactgaat caaaaaagca gctcctgaaa gttcgattaa
    38041 aatctacttt caggagctgt tcaagcttga cattattgat tttccaatcc ttcatacact
    38101 tcatctgtta caggttctaa aaactctgaa ttaccagcag tgatcgccaa atgttcaaac
    38161 caactgtctt ttgtcgcacc atgccaatgt ttaatccctt tgtgcgttac gacgacatct
    38221 ccagccatta atcgtcttgc tggctttcct tcttcctgat accagccttc tcctccggtc
    38281 acaagtaaga tttgatagcc gtctttatgg acatgccagt gattgcgaca acctggttca
    38341 aaagttacat tacctacacc aacagaaact tcgggatcat tcactaacat attcagatag
    38401 ctttacccgg taaatacttg agcgtaagct tcgttttttt cacctgctgg aaaaatcacg
    38461 ccattgtgta tttcttcgtg ttttgtcgtc atttacgcct ctttcttatc ttcgctattt
    38521 tcttctaaat agatttcttt tgctaaacta aaagctgacc aagcttttgg ccatcctaca
    38581 taaaaagcta aatgggtaat gatttctgct atttcttcac tagtaatgcc attttgcttg
    38641 ccaatcttca gatgagctgg caattgttca aaatttcctc ctgaaattaa tgcagatatg
    38701 gtgatgatac tacgctgatg agcagataat tcttctctgg accatacttg tccaaataaa
    38761 acatcatcat tcaattctgc aaattttggt gcaaaatctc ctaattgatc tcgtcctgcg
    38821 gtttgttttt ctgccatttc tcttattctc ccttcacgac tgttaggtga ttcaactatg
    38881 gttctaaggc aactttattt tctattgttt cttcgcattt cattttaaat gtagtctttc
    38941 agcctgtcca atgcttagtt tattcagtcg atatgctttt taagcatagt tgctaacgct
    39001 ttttttat
//
LOCUS       DAPBAF010000029        36706 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.029, whole genome shotgun sequence.
ACCESSION   DAPBAF010000029 DAPBAF010000000
VERSION     DAPBAF010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 36706)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36706)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36706
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.029"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            <1..300
                     /locus_tag="RD451_001656"
     CDS             <1..300
                     /locus_tag="RD451_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HDT7566917.1"
                     /translation="DGLAPGAYQLVETQAPTGYELDATPVTFKIEKEQEVAIFLTKEN
                     RKVADSSDIRGNNPTSSGNKHLPKTGETIISQFILSILGVLLVFISIKFRKKRNI"
     gene            complement(724..894)
                     /locus_tag="RD451_001657"
     CDS             complement(724..894)
                     /locus_tag="RD451_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDT7566918.1"
                     /translation="MPRLTNYFLSCTNPKEIEFLVTDMNATYFQLTKHVLPNAKLVID
                     RLLGFSTPFKEA"
     gene            complement(1088..1267)
                     /locus_tag="RD451_001658"
     CDS             complement(1088..1267)
                     /locus_tag="RD451_001658"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566919.1"
                     /translation="MPMVIRLKKQRYTCKNCRSHWNAQSYFIRPRHSISNHVRHKITS
                     LLTEKVSLFFISKSC"
     gene            complement(1277..1501)
                     /locus_tag="RD451_001659"
     CDS             complement(1277..1501)
                     /locus_tag="RD451_001659"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566920.1"
                     /translation="MNGSIKKILRSIDKNLMITEVSYETLQKKKTLIVAAVLFPAPCV
                     CRNCGSAVVDGNRKLMVVKNKKKETIVHFE"
     gene            1654..2766
                     /locus_tag="RD451_001660"
     CDS             1654..2766
                     /locus_tag="RD451_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HDT7566921.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            complement(2844..3137)
                     /locus_tag="RD451_001661"
     CDS             complement(2844..3137)
                     /locus_tag="RD451_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HDT7566922.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            3305..3619
                     /locus_tag="RD451_001662"
     CDS             3305..3619
                     /locus_tag="RD451_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HDT7566923.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            3640..5619
                     /locus_tag="RD451_001663"
     CDS             3640..5619
                     /locus_tag="RD451_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HDT7566924.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            5632..5958
                     /locus_tag="RD451_001664"
     CDS             5632..5958
                     /locus_tag="RD451_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HDT7566925.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            5974..6492
                     /locus_tag="RD451_001665"
     CDS             5974..6492
                     /locus_tag="RD451_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566926.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            6492..7844
                     /gene="celB"
                     /locus_tag="RD451_001666"
     CDS             6492..7844
                     /gene="celB"
                     /locus_tag="RD451_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HDT7566927.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(7928..9433)
                     /locus_tag="RD451_001667"
     CDS             complement(7928..9433)
                     /locus_tag="RD451_001667"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HDT7566928.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLEFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(9525..10115)
                     /locus_tag="RD451_001668"
     CDS             complement(9525..10115)
                     /locus_tag="RD451_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDT7566929.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            10294..11940
                     /locus_tag="RD451_001669"
     CDS             10294..11940
                     /locus_tag="RD451_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HDT7566930.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYFQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            11989..12708
                     /locus_tag="RD451_001670"
     CDS             11989..12708
                     /locus_tag="RD451_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HDT7566931.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            13187..14134
                     /locus_tag="RD451_001671"
     CDS             13187..14134
                     /locus_tag="RD451_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDT7566932.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            14146..15066
                     /locus_tag="RD451_001672"
     CDS             14146..15066
                     /locus_tag="RD451_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDT7566933.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            15107..16564
                     /locus_tag="RD451_001673"
     CDS             15107..16564
                     /locus_tag="RD451_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDT7566934.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            16909..17523
                     /locus_tag="RD451_001674"
     CDS             16909..17523
                     /locus_tag="RD451_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HDT7566935.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            17516..19240
                     /locus_tag="RD451_001675"
     CDS             17516..19240
                     /locus_tag="RD451_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDT7566936.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            19237..20688
                     /locus_tag="RD451_001676"
     CDS             19237..20688
                     /locus_tag="RD451_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7566937.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(21161..23314)
                     /locus_tag="RD451_001677"
     CDS             complement(21161..23314)
                     /locus_tag="RD451_001677"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HDT7566938.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDREYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(23316..24362)
                     /locus_tag="RD451_001678"
     CDS             complement(23316..24362)
                     /locus_tag="RD451_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDT7566939.1"
                     /translation="MTQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            24512..25801
                     /locus_tag="RD451_001679"
     CDS             24512..25801
                     /locus_tag="RD451_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HDT7566940.1"
                     /translation="MVYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDACRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            25814..28516
                     /locus_tag="RD451_001680"
     CDS             25814..28516
                     /locus_tag="RD451_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HDT7566941.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            28501..29358
                     /locus_tag="RD451_001681"
     CDS             28501..29358
                     /locus_tag="RD451_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HDT7566942.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(29429..30328)
                     /locus_tag="RD451_001682"
     CDS             complement(29429..30328)
                     /locus_tag="RD451_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HDT7566943.1"
                     /translation="MVQLVCNCTERSTLVKITITLPMNHPETTIRDLLEKEWLVPRKV
                     RHFLRIRKNVWINQQPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDE
                     HLIIVDKPAGMKTHPNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKN
                     PFVLPILGRMLEQKMIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSA
                     LTHVTVNKVLSEQTQVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHAL
                     ELHMIHPFTQEKIVGKALPGLWE"
     gene            30497..32668
                     /locus_tag="RD451_001683"
     CDS             30497..32668
                     /locus_tag="RD451_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HDT7566944.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPAVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            32736..33077
                     /locus_tag="RD451_001684"
     CDS             32736..33077
                     /locus_tag="RD451_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HDT7566945.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(33353..35107)
                     /locus_tag="RD451_001685"
     CDS             complement(33353..35107)
                     /locus_tag="RD451_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7566946.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLSFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQCISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(35118..35954)
                     /locus_tag="RD451_001686"
     CDS             complement(35118..35954)
                     /locus_tag="RD451_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HDT7566947.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            complement(35956..36639)
                     /locus_tag="RD451_001687"
     CDS             complement(35956..36639)
                     /locus_tag="RD451_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HDT7566948.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLMPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
BASE COUNT        11843 a         6446 c         7481 g        10936 t
ORIGIN      
        1 gatggcttag caccaggagc atatcagctg gtagaaactc aagcgccaac ggggtatgaa
       61 ttggatgcga caccagtaac tttcaagatc gaaaaagaac aagaagtggc gatcttttta
      121 acaaaagaga atagaaaagt tgctgatagc tcagatataa gaggaaacaa tccaacaagc
      181 agtggaaata agcatcttcc aaaaactgga gaaaccatca ttagccagtt tatattgtca
      241 atattgggtg tgctacttgt tttcatcagt ataaaattta gaaagaaacg aaatatatga
      301 gctaaaataa aaaattgaat aagcatagtt tttaaaatca actagtaccc atcaattgaa
      361 tggaaactac cgattttaga aggggtatac aaacaaatat tagtatcgga gtagagaagg
      421 ttgaacccaa ccagtaaata agtaaagaca attttgtgct gcgttgagaa gtgaaaaata
      481 aacctttgta gtaatactag ttaataaaaa atatacaaaa acactgcgaa aatcattctt
      541 gagtttcgca gtgttttttg cctaatgact caagtttatt gggtaatact ttgattttct
      601 ttctacaaat aatcagcgat cagttgtaat tttttctcta gttttaatgg ctctttgtca
      661 ataaggagaa aaacaagtcg ggtcttttgt ctcggaaagc ttcaaccaac tcgtgaataa
      721 aggttacgcc tccttgaaag gcgtggaaaa accaagtaat cgatcaatca ccaatttcgc
      781 atttggtaga acatgtttgg tgagctgaaa gtaggtggcg ttcatgtctg taactaagaa
      841 ttctatttct ttaggattag tgcagctaag gaaatagttt gttaatcgag gaattttttg
      901 tgtaggtaaa ttttctcgat taatttttct gtctcgccat ccgcggaaat aaaactcagt
      961 ttatcctcaa cggaaacgtg agaacgaaat tcacaaccct caacactcaa gacagaattc
     1021 ttttggaaga ctttggtaaa tagcttctca actctttcaa tgtgcgaata acggttgtca
     1081 aagataccta acaacttttc gaaataaaaa ataacgacac tttttcagtc agtaaagaag
     1141 tgattttatg tctgacatga tttgaaatcg agtgccttgg acggataaaa taactttgag
     1201 cgttccaatg gcttcgacag tttttacagg tatagcgctg cttttttagg cgtataacca
     1261 ttggcatatg attatattat tcaaagtgga caatggtttc cttcttcttg tttttcacca
     1321 ccattaattt cctatttcca tctaccacag cagaaccaca atttctacag acacatggag
     1381 cagggaagag aactgcagca acgatcaatg tttttttctt ctgtaaggtt tcgtaagaga
     1441 cctctgtaat catcaaattt ttgtctattg atctcagaat ttttttgata gaaccattca
     1501 taaagcatat cgttctctca gttgtttatt ttgtggtgat ttaatcatac aagaaaacga
     1561 tatgtttttt tataaaaaca tgaataggaa aaatagttga caagaaaatg acaacgccat
     1621 atgatgttcc atagtattta caacctgtca tagatgactg taaaaaataa aagtaaaaag
     1681 aaaggacgac aacaggtgga tttttatcag tctctacaac tagatccgtt tattttaaaa
     1741 caaaaaatac gagaagcagc ttctaaaaaa gaaaagtgca tgtatatttg ttcattgttt
     1801 ttacgatcat tattcatcgt attgtttgcc atttgtttta tcattataat tacaacatta
     1861 tttgaatcga agcataaacc atacgctgtg gttttattct gtatgttgat gagtattcgt
     1921 tttgttgact ttggttataa gatttcccat tcgatcatag gtttagcaat cgtcatgttc
     1981 tcactattag tagcaccgta tgtccagctg atcaaatggt cagttatggg catgttgatt
     2041 cattttattt tactaagcag catattaatg gcaaccgcta gtgatcccaa aatggggaat
     2101 gcttctttgt acggcttttc atatctcttt attgtttatt cgttacctaa agattcgttg
     2161 aacaagaatt tctttacaca aacaagtagc ttattatttt tgtttttttg ttggttttca
     2221 gttcttcttt acagaaaaca tcgagaaaag aacaaagaca aaagcttgtt taaagagatt
     2281 tttttgaaag gcatgtattc gcaggaaaaa atttggatgc tcatctatgc atttggcatt
     2341 agtcttttga tcgttgcagg agagtatgtc ccttttcagc gattgatgtg ggcagggttt
     2401 gcattttctt ctattgtatc tagctatgga ttgatgtcga ttggtttcaa agaacgagca
     2461 gtagaccgaa tcattggctc attgattgga tgtgttttat ttattggtat cagccaattt
     2521 attcctttta actgggtcgg tatattaggt ggtctagctt taggtgtttg ttctacctat
     2581 agatataaaa cagtttttaa ttcttttggt gctttggcaa tcactgccag tttattcggg
     2641 gttccaggag cagtaacgat ccgcattttt gagaatatcc ttggggtatg tttaggaatc
     2701 atgtatattg gggtgactga aatacttatc cgaaaaataa gagaaaaaca cggtttgaat
     2761 cattagatga gatcgaataa aaaataagga aaaagtgaag atacacatgg atgataaatt
     2821 gctatcattc catgtgtatc tttttacggt aaatcagtga aacgttcgac tttcattttt
     2881 aatttatact ttttacggag ttcgtttatt tgagccatca tttcggattt gtgatgcttt
     2941 tcgattgctt cttcatcttt ccaacggtcg atcagtaaaa gagattctgg atcttctagt
     3001 ggaaagtaat agtcatattt ctcgtttcct tcttctgcac gaatcgcttt gacaatgttt
     3061 ctttcgacca tttcttctgc aaattttctg gcttgtccat ttgtacttgt atacaaaata
     3121 ttcactgtga tactcactaa atcccctcct gaaaaaattc tatcactagt atatcacggt
     3181 gccagaaatt attattcaag atatgataca cattttttcc gcaatgctac ggaaatatat
     3241 attttgaata gaaaacgctt acaagatatg cttggtttat aaaaataaaa ggagtgattg
     3301 atttatgaaa aaagcattga ttatttgtgc ggcaggaatg tcatcctcga tgatggcctc
     3361 aaagacaacg gatttcttta agcaaaaaag agaagaggta ctcgtagatg cagtttcagc
     3421 tacagaaggc gataatatga ttaagaatag tgattttgat ttatttctga tcagcccgca
     3481 aacgacgatg tttttggata aattcaaaaa attaggagaa tctgttggaa agcctgttgt
     3541 tagtatccct ttccaagcgt atgtcccaat ccctacaggc atccagaagt tagcagaggt
     3601 gatcgaagag aacatatgat ggaataggag tggatgataa tgaaacagaa ggaaaaattg
     3661 ctgttgagat atttgattga tcacaagaag gagtatgtca ccagtcaacg tttagcttct
     3721 gaattgttat tatctgatcg gacaatccgt aattacttgc agcggatcaa agagttagta
     3781 gaaaaaaacg gaggtaagat cattgctaaa ccaggttatg gctaccaact gcatatttta
     3841 caaagactga catttgactt gtttttgagt cggcaagaaa tagtacctgg atatgctaga
     3901 gaaccgcaag gattttatga gtccgaagat cgacaaaagt atatattgaa ccaattgctt
     3961 ttggaagatg ccattctttt tatggatgat ttggcagaag agctttatat cagtcgttcc
     4021 agtttgacaa aggacatgca agaaatcaag gagcgattga ttccatattc actaaaaatc
     4081 gtttctaagc atggtcaagg gacatggatc gaaggggaag aaagaaatcg acggcatttt
     4141 atcatggata ctttttttgg aaaccattat ggaaattcat tgaaagaata tttagggcaa
     4201 agccgttttt tcccagacat cagttttgaa gagctagtca ttatcattct cgatgaaaca
     4261 agagaagcta agttaaaagt ttcggatttt atcatacaga atctgacttt acacttggct
     4321 ttggggatca aacggctccg agaagggttt gaaatcaagg aattaggcat cgaacaagaa
     4381 gtttctaagc gagtagagta tcaagtggcg cagcggatcg ttcaacgtat tgaggtaatc
     4441 gcaggtgtat cgtttcccga agaagaaatt gcttatttga cattacatct catggctaag
     4501 tcgaatcaca aagaaaatca aaatgatcag gaactatcaa aggaattagc gaaagttctg
     4561 aaaagattgt ctcaggaatt tcatttttca ttagtagagg atctccagct tttcaatgga
     4621 ctactcgatc atttgtcacc gatgatgatt cgattgagcc gaggtattcg cattgagaac
     4681 ccattgactg aggagataaa gaaagaaaat cccaaagtct ttgacgcagt aaaaaggcat
     4741 ttcagcaaca tgccggcttt gaaaaactat accatcaatg aagatgaatg ggcctatttg
     4801 gctttgcatc tcatggcggc attggaaaaa gaaagagctg cgcataaact acatgcattg
     4861 attatctgtg caacgggtta cggcagtgcc caactattaa agaatcgcgt agtcagtgaa
     4921 ttcggtaaaa atattacagt ggtaagtgta aaaggctatt atgagatcaa tgaaacaact
     4981 ttaaaaggaa tcgacctgat tatttcttct attgatcttt cgacaatgtt tttcaaaatt
     5041 ccagttttac atgtcagtat ttttttgaat gaagatgatg ttcgtaaaat acgaaaggta
     5101 gttggagaat ctatacccta tcattcctca gatagaccga taccagcatt ttctctacag
     5161 caaaaaaagc agatttacac cgaacagttg tctgaaaaat ttttcaagac ttatacgtac
     5221 gaaccgaaaa aggaagaaat tcttcatgat ttgctgcaaa agctgagcat aaatgaagaa
     5281 gaaggatata taagagaaat gcgaaagcag atccagcaac gtgaaaatat gggacaaatc
     5341 atattcagtg atacagtggc agtcccacat cccgctgttc cagttggaat cgaaacaaag
     5401 gtagccgttg cattgattcc ttctgggatg cagtgggatc aatatcaaga aattcatttt
     5461 gtttttttag tttcgccttc ttatgtcgaa aatgaaggaa ttacggtcgt gactaaagca
     5521 atcgttaggt tagttgacca gctaaaagta cagcaggaaa tcttagctga acctattttt
     5581 gagaatttca gcagtaaatt tatcaaactg atcgaataag gaggaaaaca gatggctgaa
     5641 aaaataaaca gtgaaacact acaagtgact tcttttgata tcattttcca tagcggaaat
     5701 gcacggacac tgatacatga agcatttcgc tcgatgcgta aagagatgtt tgaagaagta
     5761 gaagagaagt tgcgacaagc aaatgaagag attcttcatg cgcatcagtc acaaactcaa
     5821 cttctgaaag aatatgccag cgggacaaaa atagaaatgg aaattatcat ggtccatgca
     5881 caagatcatc tgatgacgac gatgacatta ttggaagttg cacaggaaat gaattatttg
     5941 tatcaaaaaa ataaatagaa aggaaggatc attgtgcagg atacagtaaa aaggaaaatc
     6001 gaattagaaa aaaagcaact tagtttgaaa aacatgtatt tcaatcgtta tctaatcgta
     6061 cgttacctga ctgccttttt ctttttcatg aacatgcaat ggatgattct gcttctatca
     6121 gctaaaagtt taggaagtag tttaccgatg attctgattt tagctatttt gcctgcagta
     6181 ggagaacaag taaagcttta tcgaaaacac caaacgaacg ttccatggac aaagtggtat
     6241 tttttgttcc agagtgtctt taatttatta gtgattccag tgttgtttac ctcaggattt
     6301 acattcttgt atccttttat ggcaaataac aatggaggac agttatttgt tttcattctt
     6361 gttgtaagcg gtatttttgc cagtgcattt atacagtatc gtttaaagaa aatttcactc
     6421 aaccaagacc aacagtatat ccgtattaaa caatatgaaa aagcgttata tttaggaaag
     6481 gagaataact aatgtttgat tttttgcaga aatacctgat gggacctatg gggaaaattg
     6541 cgcaacttaa aatcgttcgg gctgtcatgg cagcggggat ggcttctatt cctttcacga
     6601 ttgtaggctc gatgtttttg gttttaaata ttttgccatt accgttccca tttttagaag
     6661 gattttttaa tgcaactttt ttcaaagtta gtgacttgta catgatcgtc aatacaatga
     6721 cgatggggat tttatctatt tactttgcca ttgtgtttgc ttatgaatta acgtcaattg
     6781 aacgagatga acaaaaatta aatgttaatc cgctcacggg ggcattacta tctgtttttg
     6841 cattctttat gtgtatccct gaattgatca tgactgatgg taaaatcagc ttgattgctt
     6901 ctatcaatga gacagaaact gtagtaaatg gtattaggat gggctctttt gtcgaacgtt
     6961 taggaacttc aggaatcttt acagctatta ttatgtcgat tattgcggtc gaattgtatt
     7021 gtatgtgtgt caagagaaat tgggtcataa aaatgccaga tgttgttccg ccaggagttt
     7081 ctcgttcttt cactgctctg atcccaacat ttgtcattgc gtttgtggtg atgatcatca
     7141 atggattatt agttgcacta ggaacggata tcttcaaaat gattgctatc ccatttgggt
     7201 ttgttacgca gttgacgaat acatggcttg gtgtcatggt gatttatttc ttgatccatg
     7261 cattgtggat cgtagggatc catggagcga atatcatcac ttctttcttg accccgatcg
     7321 tattagctaa tatggcagct aacgcacaag gcgcaaatta tccgttggca ggagaattca
     7381 acaattctta tgtaaccgtt ggtggatcag gtgcgacttt aggattgatc atctttattg
     7441 cattcctcgc gaaatctgat cagctgaaag tgttaggaaa agcctcactt gtaccaggat
     7501 tattcaatat caatgaacca atcattttcg ggatgccaat cgtctacaat ccctatttag
     7561 cggttccgtt tttcttagct ccgatggctt ctgctacact cgcttatttt gccattcggc
     7621 tggaaatcgt caaaccgatg cttgcacaga tgccgtggcc ttcaccagtc gggatcggag
     7681 catttgttgg tagtggtggt gattggaaag ctgctgtgtt agcagtcatt tgtgcaatca
     7741 tcgcattcat tatctggttc ccatttatca aattctatga taataaatta ttaaatgaag
     7801 aaagagaaaa ggcagcagaa ttagctagtg aaaagttaaa atgatttcta agaaaaaagg
     7861 aactgtgaca aaaaatcaca gtcccttttt ttcttagaaa tgggaaacca ctagtatata
     7921 aataccatta ttcttcaatc aaccgcttca cgattgcata atccccttca taaggttcat
     7981 ctacaccatt gattttttga tagggatcca cgccttttcc cgcaataacg actgaatctt
     8041 gcggagcgct ttctgctaaa gcgcgtcgaa tcgcttcagg acgatccatt tcataatgaa
     8101 cgatcaaatc tggattagta attgcttcat tgatttcttc cgcgattttt ttcggatctt
     8161 caaatgctgg gtcatctgcc gtcaaaaagg cgatgtcagc tgtttctgat agcacttttc
     8221 caaaatcatg tcgacgggag attgctttgt ttcctgggct gcctaataca acaattacac
     8281 ggccatctgg atgttcattt ttggcaaatt ccagcaatgt tttcaagctt agataattat
     8341 gtgcatagtc cacatagaca tgcgctccat tggattggat caattgatcc attcggcctg
     8401 gtacacgagc ttcttttaat ccgtcttgtg catcttgact ggaggcacct gttagtgctg
     8461 cggcaatgat cgcactggct gcattttctt ggttgaatcc tccagccagc aaaatatcat
     8521 aagcagtatc gcagatagct aagcgatctt catgagaaga taaagtaaaa ccgtgagtac
     8581 ctttatctga acggatcact tgataattgc tttcttccga acgaccataa gtgatcgttg
     8641 gaatctggaa tagatcggct gtttccctaa gtaaatcaaa atagtcactt tcatgattta
     8701 aaacaactgt ttttgaattc aagatcaatt gtcgcttgca atagaaatag tcatcaaatg
     8761 tcggatgttc gatcggactg atatggtcag gcgagatatt caagaagatt ccgacatcta
     8821 aagtcaagcc gtatacgcgt tgtgttttgt aagcttgtga agaaacttcc atcactagat
     8881 gagtcatacc attttcaact gcttctgaca tcatacgata taaatctaat gactcaggcg
     8941 ttgtcaaatg ggatttgaaa tatgttttgc catctaacgt tgtattcata gtagaaagca
     9001 atgctgtttt tttatttgtt gtgtgatcca agattgcttt tgtaaagtac gcagcagttg
     9061 ttttaccttt tgttccagtg aatccgatca ctttcaattt attttgcgga tagtcgtaaa
     9121 aagccatagc aagaagcgcc attgctttac ggatatccgt tacgatgatt cctactgctg
     9181 aattttcgta tggttgttct gatacataat attgaatacc ctgttcgatt gctgaatcca
     9241 aatattcttc tttgaaattc attcctttac agaaaaacaa agtagaagca tcagcttttc
     9301 ttgaatcata acttaactga agaaattcag ctttttctgg tacatcaaga tgccagcctc
     9361 ttgttgaaac aaattctttt aatagatttt cttttaatag taaatgacgg atgtcttcta
     9421 aagagaagct cattgattga tccctcgctt tattcaattt cttggtttat tatagcacac
     9481 tctttttaat atatcgtttg tttccgctat gacaaaatcc agctttattc aaattttctt
     9541 gacacagggg acaagcggat gagtattttc ataaacaatg aactgactgt aatagatagg
     9601 agaacgaata gtgtctccaa caatccaaaa acataataat tcaaaaagac gataagacta
     9661 ttggtaagta aaagtccttg cggcattgga agccgaaaaa atttgtggaa aataatcggc
     9721 ggtatcgtta taccgccatt tgaggccccg actgtgtaca atgtgtaaac cccaagactg
     9781 aacaaaagac ttcctgaaat cagtgaaaag aaatgtgagg agatcatttc cacttttgga
     9841 acaatctcta aaacaacagg aaaaagcaga cttcccgcta cagtcttaaa aaatactgat
     9901 tttcctaata ggacagcggc tagaagcagc atcataagat tgatgctcca aacagtaact
     9961 gagcgttgga tagaaaaggc cgtttcaact aaatgtccga tggcgcccac tccggcggaa
    10021 gctatatcgt gagggagcaa gaaccaattc aatccaactg tgataaagaa aagacctaaa
    10081 aatataacgg gtagtttttt tatttcttgt gtcattgata tctcctataa atgttagcca
    10141 taaaaggctg tatatttctt tactttacca aaaaaacgaa accgaattca aaaaaacaat
    10201 tgttcttata aaagttatat aaaatcgatt gccagtttct gttttaccaa ttaaaatgat
    10261 agtaatgttt tgtagaaagt tggaatctga ccgatggata atcaaagaaa accagcatta
    10321 gatcaattaa caccgcaaga aaaaatggca cgaggctctg cttggatgac cgccagtaat
    10381 atcatttcaa gattgctagg cgctgtctat atcattccct ggtatgcttg gatgggcgaa
    10441 aatgctaagg ctgccaatgg attattcaat atgggataca atatatatgc attgtttcta
    10501 ctgatctcta cagcaggaat acctgctgcg attgcaaaac aaactgcacg ctataattca
    10561 ttgaatgaat atggcacttc acgacgatta tttatccgtg cattacagat gatgggcggg
    10621 ctaggcctgt tgtttgcttt gttcatgtac atcgcctctc cttggctagc tcatgcttct
    10681 ggtggcggag aagaactgat tccaacgatg cgttctttga gtatcgctgt attggttttt
    10741 ccttgtatga gtgtgatacg agggtatttt caaggcaatc aagaaatgat gccttatgcg
    10801 ctgtcgcaga ttgtagaaca ggtggcacgt attttttata tgctattggc tacattcatc
    10861 atcatgaaag tcatggatgg tgactatgtg acggcggtca cgcaatcaac tttcgcggca
    10921 tttatcggta tgctagcaag tattcttgtc cttttgtatt ttttgaagaa acatcaagcg
    10981 tatacatcgg cgtttattca ctacagcgaa aacaaaataa atattgcaac gaaggaattg
    11041 ttgttagata ccgttaaaga agcgattccg tttattattg tgggttcagg ggtaacgatc
    11101 ttcaaattag tcgatcagtt cacttttatg aagatcatgt ctgcatccac cgagtattcc
    11161 aatgcacagt tactggatct tttttcgatt tttagtgcca atccagataa gttgacgatg
    11221 gtagttattg cattggcaac atcgatcgcg tctactgggt taccgttgat tacagaagct
    11281 gttacgttga aagatcgagt aggtctggca aaattgacaa gcggaaattt acagttgttt
    11341 tcatttttta tgtttccggc gacatttggt gttatgttac ttgcctatcc gctaaataca
    11401 ttattttata caccggattc tctaggaagt aatgtactga tccaagcaag ttttgtagga
    11461 ctcttcctag gactatatat gctagtttcc aacatgctgc aaggaatgtt tgaaaacaag
    11521 gcggcaatta attatttggt tattgggttt ctagtgaaac tccttcttca atacccagcc
    11581 attcgtttat ttgaagtata cggcccttta ttggcgacaa tgatcggatt tgctgtgtct
    11641 tgtaccttga tcttaaagag aatccatgaa gtagcccgct ttaaaccaag ttttgtctgg
    11701 cgcaggacat tgctgatctt tattcttacc ttgattatgc ttttggcttc gtggatcaca
    11761 aagatgattt ttggtgcttt tttaaacgaa gatagcaaat tccagtctct attgttgatt
    11821 cttgtagtag caggtatagg ggctttagtg tatggttatt tagctttgaa aatccgcttg
    11881 gcagaaagac tactaggacc aggaatagcg cgtttacgac ataaattaaa aataaaataa
    11941 gtgaatcaga agagctagat tgatgctctt ttgaaatggg ggaaacgcat gcgtttagat
    12001 aagtttttag cagatatggg acttggcagc cgcaaagaag tcaaaggatt gatcaaaaaa
    12061 ggaacgatcg aagtcaatgg acaagtggtg aaaagcgata aagcgcaagt aaatgaattc
    12121 gaagatgcgg ttacttattt aggagaaatc attacgtatc aaaaagattt ttactacatt
    12181 ttgcataaac ctgcaggagt catttctgct actcaggata atcatgatca aaccgtaatc
    12241 gatttattgg aagaccagga ttatcgggaa gatctttttc cagtcggccg attagataaa
    12301 gacacagagg gcctcttgat tttaacgaat gacggggtgt ttgcccatca gttactatca
    12361 cctaaaaaac atgtggagaa agaatatcta gctgaggtta gcggtataat gacagaagaa
    12421 gatatccgtt tatttgcaga aggactgatt attgatggcg atgagcagac attgccggca
    12481 aaactccaaa ttgatcaagt agatcaagag acagaaactt caattatccg tctgattttg
    12541 catgaaggaa agtttcacca agttaagcga atggtcaaag cagtaggaaa agaagtctta
    12601 tatttaaaaa gaatccgtat gggaaaattt tggctgccta aagatttgaa taaagggcaa
    12661 tatcgaccca tgaccaaaga agagctagaa caagtgagag aaaaataatt gaatggatag
    12721 ctaaaagaat aagcagagta gttgtagcgc catctgaaaa gcagacttgt ccgtctgact
    12781 ttcggatggc ttttttgtga aatttcggct tatttccgta gaagctactt ctggaacacc
    12841 gtttgttcgg aataagggac tgtgacaaga cttttgttac agtccccatt gttccttgtg
    12901 actcagagtt agatagtaag gacacgatct ccctaatact caggccaaaa cgctgaattc
    12961 acaacctctg ataaacggtg ttcaatcagc tgaccctcgg tattagctca aaaaacggca
    13021 aaatatgagg aactattttc ccgttttttt ctctaatact caggccaaaa cgctgatttc
    13081 acaacctctc ctatactttg tttcattttc cctatacttt gtttatttat tctcattatt
    13141 gaaagcgcta taattacgtt gcgaatgaat cgaaaggggt ttttagatga aaaaacgaaa
    13201 ggggttcaat cattttttta tgaatctatg gcgttataaa gcacttgtcc tgatggctgt
    13261 accgggtatg ctttggatga tttttttctt ttacatacct gtaatggcga atgtcgtagc
    13321 attcaaaaat tttcatattt cagcagatgg gttcttggct agcttgaggg aaagtccttg
    13381 ggtgggttgg gaaaatttca aatttttatt ttcttcggat caagcatttc tcatcactaa
    13441 aaatacaatt ttatataatg tagcatttat ccttttgaat ctgctgatct cagtcgtatt
    13501 tgcaatcatt atgagcgagt tgagaaataa acgactcgtt aaagtttatc aaacgatgtc
    13561 cttactacct tattttctat cttgggtcat tatcagttac tttgtttacg cttttttaag
    13621 tcctgacaaa ggaatattca atcagtggat cactggacat ggaggagaag ctgtcaattg
    13681 gtataatgaa ccgaaatatt ggccgtttat cttggtgttc attggtacat ggaaagggat
    13741 tggttataac agcattattt actttgcatc tgttatggga atcgatccga cttattatga
    13801 agctgctatg gttgatggag ctagcaaatg gcagcagatc aaacatgtga cgataccaca
    13861 acttattcca ctaatgacga ttttaacgat tttagccgta ggaaacattt tccgagctga
    13921 ttttggcctg ttttataaca ttcctaggaa ttccggtgca ttatatgatg tgactcaagt
    13981 tttggatacg tatatctaca atggcctgac atccacagga gattttggta tgacggctgc
    14041 tgcaggactt taccaatcag ttgtcggctt tgtcttgttg atgatcacaa atacgatcgc
    14101 ccgacgtttt gatagcgatt ctgcattatt ctaaggagga aaaaaatgaa aaaaaagaaa
    14161 gtggagagag tccaagtccg ctctttcaat aagacggcta attttttctc taatataatg
    14221 attgcactct ttgctatttc ctgtattttg ccatttatat ttgttatcgc catctctttt
    14281 accgatgagt ccatattgtc gactcacggg tacagttttt ggccagaaaa gttcagtata
    14341 tttggttata cgtacttgtt cgaccagatg caggataaaa ttttccaagc gcttttcgtc
    14401 actgtacttg ttactgtttt aggtacactg atcaatagca cggctacttc tttatatgct
    14461 tatgcgattt cacggtcaaa ctttccattc cgtcgttttt ttaccgtttt ttgtttgatt
    14521 acgatgttgt tctcaccagg gatggtggcc aattatcttg ttatgacaaa tcttcttcag
    14581 ttaaaagata cgatttgggc attgatcttg ccaatggctg tcagtccctt caatattatt
    14641 gtgatgcgca cattctttaa acgttcggtc tctgattcga ttattgaatc ggcacggatc
    14701 gatggagcta gcgaactgcg aatatttgtt cagatcgttt taccgttagc tgttccaggt
    14761 attgcgacaa tcagtttatt tgccgcattg ggttactgga atgactggtt caatgcttta
    14821 ctatacatcc aagatgataa gctagttcca ctacagtatc ttttgatgaa aatccaaagt
    14881 aatattcaat atctgacaca aaattcagga gcaggaagcc aattgacagg cggattagcc
    14941 tcagttccag gagaatctgc cagaatggcg atcgtagtca tctcgacgtt gcctattgcg
    15001 atcagctatc catttttcca gaagcatttt gtcaaaggtc taacaatcgg cggagtaaaa
    15061 gaataaagaa acaaaaatat aaatcataaa attaggagga agaaaaatga agttatggaa
    15121 gaaactagcc tttacaggtg tttcagcgtt gttgttggga acattagcag catgcggagg
    15181 ttctggttct aaagaccagg cagaagctag caattcggac actttgcaga tgtatcaaat
    15241 cggagataaa ccagataatt tcgatcaatt gatggaagta gcaaacaaac gaatcgaaaa
    15301 agagatcggt gtaaaagtca atatcaatta cattggctgg ggcgattacg aaaagaaaat
    15361 gaacgtcatc atttcttccg gggaaaatta tgatatcgcc tttgcgaaca actatgtttc
    15421 caatgcccaa aaaggagcct ttgctgattt gactgaatta gcgcctaagt acgctgaaaa
    15481 agcttataat gatttagatg aagcatatat taaaggaaat ctggtcaatg gaaaattata
    15541 tgctttccca gtcaatggaa atgtctttgc tcaacaagta cttactttta acaaagcttt
    15601 actagataaa tacgatcttt caattgatgg aatccaatct tacgctgatg cagaaaaagt
    15661 cttgaaggaa ttccatgaaa aagaaccaaa cacggcagct tttgccattg gacaaggctt
    15721 caaagtccaa gggaactttg attatccttt agggaatacg ttaccatttg ctattgatct
    15781 ggatggagat gattcgaaaa tcatcaacca atacgataat gaaacgtata tcggactgtt
    15841 acgtacaatg catagctggt acaaacaagg actcattcca agtgacgctg caacgagcaa
    15901 taaggattat ccactagaag gaaatacttg gctaatgcgt ggagaaacac aaggaccgta
    15961 tgattatggc gatacaattt tgacaaatgc agcaaaacaa gaacttgtct caaaagcaat
    16021 tactgttcca ctaaaatcta cagctcaagc acaaatggca aattttgtcg tatcaaatac
    16081 ttcaaaaaat aaagaaaaat cagtagaact tctagggctg cttaacagtg atccagaatt
    16141 attgaatggg cttgtttggg ggatcgaggg agaagcatgg gaaaaagtcg atggttcaga
    16201 tgataaaatc aaattgctag atggttatca gccaaataca catatgtctg cttggaatac
    16261 aggaaacaac aagattctat atacacaaga gtctattacg gatgacatga ttgccaaacg
    16321 tgatcaatcg attgctgatg cagaaacttc accgatttta ggattcagct tcaacactga
    16381 cagtgtcaaa acagaattaa gtaatatttc taatgtcatg aatcaatatt tagatggatt
    16441 gaatacaggg actgttgatc cagatgaaac attaccgaaa ttgaaagacg ctttggacaa
    16501 ggctggctat gataaggtat tgaaagaaat gcaaaaacaa tatgatgagt tccgacaaga
    16561 ataataatga ataaagacaa aggggttgtg acaaaagacg tgtcacaacc tcttgttccg
    16621 aataaacggt gttcaaaagc cagtttctcg gtattaagct aaatatatgt aaaaatgtgg
    16681 aaagccatat tcacaaaatt tttcttacta ctcgaaacta agcggctatt tcacaaactc
    16741 ttggtaaacg gtgttcaatc agctgaccct cggtattcgc tcacaaaacg acaaaatatg
    16801 aggaactatt tttccgtttg tttctctaat aatcaggtca aggtgctgat tgcccaacct
    16861 ttttttgtat aatgagaaag tataaactta atgtttggag gagaagatat gttagggaag
    16921 gttttggaag agttatttat ccggatctgg gtcattataa aactaacctt gtatttctgg
    16981 atatatacat ttgccggcgg gatcatcttt ggattaggtg cggcatggaa aacagtcaat
    17041 gaactatttt atttgtacgg attcgagtat aaagaaatca caataaaaag aggctggaat
    17101 atatataaaa gaaatttttt aagaggcaat ctgctattta gtttattttt atctggtact
    17161 gctttattga gttacaattt atatttatct gttcaaatca aagggctcat ttttttagct
    17221 attgatttta ttttactttt tgccttgctc tgcctatttg ctacttatca atacagtatg
    17281 attttagata gtgaatatac gatctctgtt cctaatctgc taaagctaag ttttatttcg
    17341 gttttttcca gcttttcgtc ttttctaaaa ataattattg gtagcggtat aattttaggc
    17401 gtgacttggc aattcaaagg attgatcctg tttggtgtca ttggtctttt gacggtttgg
    17461 aatggtacga tgacaacaca ttggcgtgaa gaattagata aacagttgga aagttatgaa
    17521 taagtttcgg attctatttt caaaaggaac cttactaaat cgtctgttgc ggaaatacgc
    17581 ggttatcatg atcggtgtaa cgatgactgc taccgttatt tttagtatcc atacttggga
    17641 acaaaatcaa aaacaggcag aaaacatgac aagtgatgcc gttcaaagca caagcagaat
    17701 gctgaatgat aaaacaacct tgagtaggat catcaaaaac cagcttgtag ggaattccga
    17761 aaagatcgaa aatgtgacga cctacttaac aaaacccata gatcagtatc tgatgtatgt
    17821 atacgaacag caaaacagta ccgatgaatt agtttctttc ccaaatcaaa tcaaagatct
    17881 ctacgcaaat tatgaagaac taagtgcgat atatatcgtg ttgaatcaac taccggagta
    17941 ttatgaatct tctagagaaa acaaaggtgg ggaaataaaa aaggggacac caaaattact
    18001 agacgccttt tatatcaagt tgcctatcac acaaggagga gctgagtcag gaagtatttt
    18061 tattggtttt caaaagaaag aactagatat gattttagaa aatctaacgt cattcaatgg
    18121 actctcttta tacatgattt ctggaacgac aaatcgacta tacacattcc atgataataa
    18181 aatagctaaa gaaacgtttg aaagacaaga aatgatcatc acagagagtc tgaagaaaaa
    18241 ttcacaattg ccgattgacg atctggaaaa aaacaatttt gttcaacacc aagaactgtc
    18301 tgatgattat cgtatattag ctgtactaga taaaaaaagt gtaaaaatcg aaacgggaaa
    18361 aaatcttgcc ccgctgatca ttggtatcat tattttagac aatatactgc ttatctttct
    18421 ttataaaaca ttcaaacgat attcacagca agtatctatc gtcatgcagg ccatggatca
    18481 aacagcagca gggaatttag agacgcggat cgacataaca aacacggaat atgaactgaa
    18541 ggaactttca atcggtatca acgaaatgtt ggatagcatc aatcagtttg tagaagacat
    18601 ctacaaatta gaaatcaaac agcaagacgc acatatgcgg gcgcttcaag cacagatcaa
    18661 tccacacttt ttatataata cattagaata tatccgaatg tatgcaatca gcgaaggaag
    18721 tgaagaatta gcagatgttg tgtatgcgtt ttccgctttg cttcgaaaca atacgaatca
    18781 agagaaaacg atcactttaa aagaagaact ggacttttgc gaaaaatatg tctatttgta
    18841 tcaaatgcgt tatcctaatc gagtagccta tcattttatg atcgatcctg atttggaaaa
    18901 gatcgaagta cctaaatttg tgatccagcc attagttgaa aattatttta aacacggtat
    18961 tgattttact cgattcgata atgcgctaag tgtcaaagtc ttgcaggaag gcaaacgggt
    19021 aaggatcatc atcaaagata atggaaaagg gatgactgaa aaacggctaa aacagattga
    19081 agaaaaactg tctcatccta aagtggaact tcacggttct atcggtctgc aaaacgtgaa
    19141 tgaacgttta cgtgccagct tcggcagcag ttattatatg tcgcttgaga ataatgagac
    19201 aggtggactg accgtttcta ttacattcaa ggagggatga gcgtgtatca agtgttattg
    19261 gtagatgatg aatacatgat tttgaatggg ttaaaaaaga taattgattg gcaaagttta
    19321 ggctttcaaa tagtagcaac agcagagaat gccaaagaag gactagctgt acttgaacag
    19381 cgacagattg atttagtagt aacggatgtg acaatgccag aaataaatgg actggaattt
    19441 attgaagcgg ctcaaaaaga acgtcataat tttgaattta tgattttatc aggataccaa
    19501 gaattcgatt atttgaaagg aggtatgcaa ttaggcgccg tgaattattt gatgaaaccc
    19561 gtgaataagt tcgaattggt tgaaagcctc aagaaaatca aaacacggtt agatcagcaa
    19621 aatgaacaaa aaaatcaaca agaaatctat caagaactgt tattcagtca atggttgaat
    19681 gaagaattgg atgaaataag tgaagaagaa ataataggac aaataagtga gaagcagcat
    19741 aggatagtat tgattcaact ggcaagaact catgatactc ttatcaatag atggttgcaa
    19801 gaacggcaac aaatctttta ctatcaacga aattacggag accgtgtatt gatcacgttg
    19861 ttgttggagg cagatgaagt tgatggcttc tgttgttttg ttcaagaaaa ctttcctgat
    19921 caggaatggc tgatcagtat cggggaagag acagattctt tggacaaaat ccctgaaaca
    19981 ttccaacaag cgaaagacaa tctacagttg catcaatttt atggagataa agacgagcat
    20041 gttttttacg cagtacaagc agaaacaaaa gatcaaacca tcgatttttc aagtttcaga
    20101 cgcgtgctgc aaaataaaca attggaagtc gctcaaaaaa tgatcactga tttttttgaa
    20161 cagtttcagt tagcagccat gatgccggaa gatatacgat attccagttt tttactgttt
    20221 atggagattc aacgggaatt gattgatctg gaagatgagg aatatttaca aggaatcgaa
    20281 aaaatccatc aggcaaaaac ggtgcaagaa cttcagcagc tacttctgtc attcatcaaa
    20341 aagcatcaga gacagaaaaa gtacagtgac aatgtggaaa aagtaatcgt aatcctgcac
    20401 cagcattatc aagaaccact tacactcaaa gaagtgtcag aaaacctgca tttaaatgtc
    20461 atgtatctag gacagctgtt caaaaaagaa acgaaaaaaa gtttttcagc ttatttgaac
    20521 catttacgta tggaaaaagc gaaacaactg cttttgcaca gtaatcaaaa catcaatgag
    20581 atagcaagtg agattggcta caacaacacc acgtatttct ctaaattatt caagaaaatc
    20641 gtcggcagat cccctaaaga gtaccgagaa aacagtggag aatcataaaa aaaaaagcca
    20701 atgtaatgaa ataacttata aaaaattgtc tagaaatcta attttgggct gttcttatta
    20761 cttgaggcaa ggcagctttt tcatgacctc tcgataaacg gagttcaaaa gccagtttct
    20821 cggtattaag ccaaatttat gcaaaaatgt ggaaagccat tttcacaaaa tttttcttaa
    20881 tactcgaaac taaacagctt tttcacgacc tctccactaa atggtgttca atcagctgac
    20941 cctcggtatt agctcaaaaa atggcaaaat atgaggaact attttgccat ttgtctctct
    21001 aatactcagg tcagaacgct gatttcacaa cctctcaata aacggtgttc aaaagcttgc
    21061 atctgcggta ataagaccaa ccaaacgaaa aatatgagga tctatttttg cttggctgtt
    21121 cttattactt gatgcaggac agctttttca caacctcttg ttaattatag tttgataagg
    21181 aaaaaggcaa atcttttgct tgatatttct tagggtgagg gatgatccct aattggtaag
    21241 agatcgtgcc gcctttcagc aaatcttgat gggtaaaata taatttcgta tattctctgt
    21301 ccatccgttt gattttatgg ataaattgtt gctgcggccg attaggcgtt gcttcaatcg
    21361 tcaattcctt tccatttgac aaaagcaaaa cagccttgtc aattaatggc ataccgataa
    21421 catattcacc ggttccaggc gtgacaggat aaaatcccag actattgaag atataccaag
    21481 cggccatact tccattgtcc tcatctccag ggtaacccat tggagaatcg tcgaaggtct
    21541 gagtcatcaa ctgtttaagc agtggctgtg ccatttcagg ttgtcctata taactgaaca
    21601 agtaaggata gtgaaaactt ggctggtttg aaatagctaa ttgtccaaat tctatcgcgg
    21661 ccatctcact catttcgtgg atctcaaaac catatcctcc tgggtcaaac gttgggggct
    21721 gattgcacag ctcaatgagt ttttctttat atctctcact gccaccatat tttccgatca
    21781 gtcctgaaaa atcgtgataa acagcaaagc tgctttgcca agcacttcct tctgcataat
    21841 cttgtcccca acgattagct gaaaatggtt ctctgaactt gccatcttta tcttttgaac
    21901 gcataaatcc tgactcatag tcaaagatat tttgatagtt caatgattgc tgctgatatt
    21961 tcttcgtcat ttcctcttct tctagtacct tggcaacttg gctaatacaa aaatcgctat
    22021 aagcatagtc taatgtgtga ttgactgatt cgtggtagtg attaggaaca tagccatatg
    22081 tcaagtaatc ttctgttcct tggcgtccat aatttggatg tttgctttga accgtagcac
    22141 ctttttccat tgccgttaga aattcaggca tcaagtctcg tcggatatct tttacagcag
    22201 catctgcaat gaccgcatcg atcaatgtcc caggcataag tccacgttca tcaggagaca
    22261 gccattttgg caaatagcca ctttctctat agctgttcaa aaaaccttcc agcatttctt
    22321 cgtatttttc tacagcaatc aaagaataaa gaggataaac cgttttatac gtatcccaaa
    22381 acccattatt tgtatagaga acaccaggtt ttatagatcg actagtcgta tcatagtgga
    22441 ttttttgccc actaggatca atttcataaa atgtttgtgg aaataaaaac acccgatata
    22501 aattatgata aaacgtccgc aattgttgtt gatcatggtg tgtgagctgt atacgatcaa
    22561 aataggactg ccattgttct tgactgtgag caaggtaagt ctctttgctt tggttttgtt
    22621 ctagttccag gttataagct gcttgttccg agctgataaa agatgtccca aatcggatag
    22681 tttgtttttt tgtctgttca aaatacaacg ggatcgagtc gctatttttg ttggaaacag
    22741 ctaactcatc aattgttaaa ggatattcaa atctcaatat aaaataaaaa gaaaaatcag
    22801 gatcttctga accagcaaaa tgtgtgattt ttccttccac tgtgtaagga tctataacaa
    22861 agagctgatg gcgtcccgga aaggataaaa gtaaaccgct gtcatttttg ctgtaatcaa
    22921 tagataagat tccgccatac atgctaggta tcaatgtaga acagatgcca taacgtaatt
    22981 gacagatcga cagatgagtc gggcaaaata tactttcttc tgggcggtaa gaactttgag
    23041 catggaaaag ggtgttctcc tgtagttttc cattgatcgg cgtaaacagc atatgactga
    23101 aatcacccat ccaaggactt ggttgatggg taagacggta gccttgaaaa acgcggtcat
    23161 caggatgaaa ccaccagctg ccgttttgat ccgtagtttg cggtgcaaaa taattcatcc
    23221 caaaaggaac gccagtataa ggctggcagt tcccattaga gaaatttggc tgattcgctg
    23281 ttgcatgtct agtatctatt tgaccgatat tcattttatt tctcctttgt tgattgtctt
    23341 ttgatgaatg aaactggaaa tttactatcg gatggtcgat cttttgtctc taaccaagtg
    23401 accaaagcat ctcccgcaag cttacctaac tgttcaaaat cttgtgcgat ggttgtcagt
    23461 ggcgggtcaa caagagctgc tgcttggata tcatcaaatc cgataattga aaaatcttca
    23521 gggatatgat aaccatgctg tctcaagaga ttcatggtct ggatagcgac aacatcgttt
    23581 tcacaaacaa aagcagttac ttcatactta gtgatataag aaagcaattc atctaatgtc
    23641 gcgcttttgt catccagtga agtgtggaaa gtcaaaccag ctttgtccaa tgcttcaagg
    23701 taaccaaggt aacgctgtcg aacggattgt ggatgagtct gcgtaccaaa caaataagcg
    23761 atttttgaat gtccctgttc gatcaaataa gaggcagcaa gcgcaccgcc ttggaaatta
    23821 tcggaaagaa cggtaggaaa aggtaactca tagatttttt tatctaatat gacgacaggg
    23881 aattctttca atgaaagctc aaaaagtaag tcaagatgtt gttctgtatc aagagcataa
    23941 taaatcaatc cgtcaaattc attgattagc tcttttgctg ttttattttg tagaaagtca
    24001 agcgtcgtca tcatgacatc aatctgttta tcttgcatca cagggttcaa tcccttgcta
    24061 aaatcaccaa cagacaaatc agcgacatat ggaagaagaa acagaatccg tcgtgttttt
    24121 gtaggagaag caagaatctg ttccggagaa gcggatttaa cgaaactgcc tttcccgcga
    24181 acgcgataaa taagtcctaa ttgctctaat tcagtcaatg cacgtttgga agtgattctg
    24241 cttactttat aggtacgtga aagttctttt tcagttggta gttggctgtc tacaggtaat
    24301 tcaccagtta aaatagccgt ttgcaaatca ttaaatattg tctggtacaa tggttgagtc
    24361 atataaacac ctcttaatga tatatcatat tcaaataata ccataatgga tgaaaaagta
    24421 aataaaaaga tattttttga aagcgtagac ataattggct gtatgaagta taatctttaa
    24481 agatatatca aatagaaaga aggttttatt agtggtttat aaagatatac caaaatcggt
    24541 gcagaaattt atggaagata tcacacaaaa atgtggggat atccatgcgg actgggcaaa
    24601 gaattttaca gcagcatttg ccaatactct gttgacaaca gtcaaaaagc aaaatgacgg
    24661 aaccaccttt ttattgacgg gagacattcc agcgatgtgg ttaagagact ctactgcaca
    24721 agttcgtcct tatttagtga ttgcaaaaga agatgaggaa ttagctgaca tgatcagcgg
    24781 gttagtcaaa aagcaatttt tttatatcaa tatcgatcca tatgcgaatg ccttcaacga
    24841 agaagctaac ggtgctggcc accaaacaga tcatacaaaa atgaacgatt ggatctggga
    24901 aagaaaatat gaaattgatt ctttatgcta cccaatacag ttggcctatc ttctttacaa
    24961 aaatacagga aaaactgatc aattcaatca atcttttatt gaaggtatca aaaaaatctt
    25021 ggacgtgttc aaaacagagc aagatcatga acactctcct tatacatttg tacgagacac
    25081 gacaagaaaa gaagatacgc tgatcaatga cgggcgaggt gcaaaaacag cttttacagg
    25141 aatgacatgg tctggtttcc gtcctagcga tgatgcttgc cgttatggat atctggtacc
    25201 atccaatatg tttgcggtgg tcgtgttagg ttatgtggaa gaaatttttc aaacgatact
    25261 cgatgataaa gaaattgtac agcaaacaca gaaattgaag aaagagatcc aagaggggat
    25321 tcagaatcac ggacgaacgg ttaatcaaaa agggcaaacg atttatgcat atgaagtaga
    25381 tggaatggga aacgccacag tcatggatga cagtaatgtg cccaatctga tcgccgcacc
    25441 ttacttggga tattgttctg aacaagagga agattatctg caaacaagaa gaacattgtt
    25501 gagtaaagaa aatccatatt tctatgaagg aaagtacgca aaaggaattg gatcctccca
    25561 tacgccagaa aaatacgttt ggccgattgc attagctatg gaaggaatga caacgtcaga
    25621 caaatctgaa aaagagcgga tattgaattt acttgtagca actgacgcag gaacacacct
    25681 tatgcacgaa ggattcgatg tgaacaatcc tgaaaattat acgagagaat ggttttcttg
    25741 ggcaaatatg atgttttgcg aattagtcat ggattacttt gatattagag tagaaaagta
    25801 ggaggtatcg taaatgaaaa agaaagtata tatcatttct catagccact gggatcgtga
    25861 atggtacatg gcttacgaac agcatcacat gcgactgatt gaattgatag acgatctact
    25921 agagctattt gaagttgatc cgtccttcaa cagttttcat ttggatgggc aaacgattat
    25981 tttagatgac tatcttcaag taaggccaga aaaaagacag gcaatccaac aagcaatcaa
    26041 tgaaggaaaa ttgagaattg gaccatttta tatcttgcaa gatgattttc ttatcagctc
    26101 ggaatcgaac gtgagaaata tgctgattgg catggaagaa agccgtaaat ggggaacccc
    26161 tgtcatgtta ggctattttc ccgatacatt tggaaatatg ggacagacgc ctcaattaat
    26221 gaaacaagct ggtatttcag cagcagcgtt tggccgtggt gtaaaaccaa ttggctttga
    26281 taatcaagtt ttggaagcag aaaactattc ttcccaatac tcagagatgt ggtggaaagg
    26341 ccctgatcaa acagcaatct ttggtctgct atttgccaat tggtatagca acgggaatga
    26401 gattccagta gaaaaagaag cagctcttgc cttttggaag caaaaattag cggatgcaga
    26461 acaatatgcc tctacgaacc acttattgat gatgaatggt gttgatcatc aaccggtaca
    26521 aaaagatata tcaaaagcaa tccatctcgc aaatgaactg tttccagatt acgagtttat
    26581 tcattctaat tttactgact atctggaagc agttcaaaaa gatgtgccag aagacttagg
    26641 ctcagtagaa ggagaattga caagtcaaga aacggatggc tggtatactt tagccaatac
    26701 agcatctgct cgggtttact taaaacaatg gaataccaag gtccagcgac agctagaaaa
    26761 tattacagaa ccacttgcga cgatggctta tgaagttagt ggaaactatc cccatgatca
    26821 attagattat gcttggaaga cattaatgca aaatcatcct cacgacagta tttgcggttg
    26881 ttcagtcgat tctgtccatc gggaaatgat acctcgtttt gaaaaagcag atgaagttgg
    26941 aaagtatctt gcacaagatt ccttagaaca gctgaccgca gcaatcgata cgaccggatt
    27001 cccaaaagac agctttccat ttgtcattgt aaatactgca ggaatggata aaactggtga
    27061 agcagaaata accatcgaat tagaaagaaa aagattcgct gaaggaatac ctgaacaact
    27121 atatcaagag ttagaaaatt tgcctaaacg taagtatcat gtagaaacaa aaagtggggc
    27181 cactatacca gctattttat ctgaagaaac tgtccaattt ggttatgatt tgccgaaaga
    27241 ccgtttccgt gtgccatata tggcaagaat gatcaaagtg actttaccat tagaaaacat
    27301 gccagcattt tcttgggaaa cattcgcgct tgtagaaggg gaagcgaaag cagaagaaaa
    27361 ggaaacaatg attcatcaga gtggacgaat catcgaaaac ggccctctac atttgacgat
    27421 tgaaaaaaat ggtaccatta caatggaaga tcgcaaaaac aaacgaaagt tgaataatct
    27481 gcatattttt gaagatatcg gcgatatagg aaatgagtat atctttaaac aacctttctg
    27541 tgatcagcca atcctatcca gtaacaaaga aaactctgaa gtaaaagtat tagtagatac
    27601 accggaaata gcaaaaataa gtattctaca ggaaatggaa atccctgttt ctgcagacga
    27661 gcgtttagaa aaagaacagc agatggttgt ggaatttcgt tatcgaaaag cagaacgatc
    27721 caaagaaaaa cgaatccttc aaataaaaac aatcatgaca atcagaaaag atagtaaaaa
    27781 aatcgacttt gaaacgactc tcgacaatca gatgaaagat catcgcttac gtgtcttgtt
    27841 tcctacaaag ttacatgtgg aacatcacga agcagatagt atttttgaag tggtgaagcg
    27901 cccaaaccat gtgtctaaaa gttgggaaaa ccccacgaat ccgcaacatc agcaagcatt
    27961 tgtcaatatt catgatgaag agtacggtgt aacagtcgga aactttggtt tgaatgaata
    28021 tgaagtaaca gaagacggac aaatcgcagt gacgctactt cgcagtgtgg gagaactagg
    28081 cgattgggga tattttccaa caccagaagc acagtgtcta ggtgagcatc ggttcaatta
    28141 cagcattgaa ctacatggac cagaagaaaa attctctact tatttgcatg catacgcagc
    28201 acagattcct ttttccactc aacaaatcaa acatcatgaa ggaacattga tttcaaaaca
    28261 acaatattta acgataaaaa gtgaaacgtt tgcaattaca gctttgaaac gcagcaagtt
    28321 tagtgataaa gtagtagtaa gaggtttcaa tatgtctagt catttagaaa aattggaaat
    28381 aactaaagac aatggaaaaa ctgtcatatt gaatctgctt gaagaaccaa cgaagcaagc
    28441 ggttgtccca ataatccaac cttatgagat tcggacaatc ggattcgagg aggaaaacga
    28501 atgtatggcg gaatagaagc aggcggaaca aaatttgtgt gtgcggtttc agatggtgga
    28561 gaaattttag aaaaattaag tatccctacc acaacaccag aagaaacatt ggatcaggta
    28621 tttgaatttt ttgatcgtta tgaattgaag ggaatcggga ttggctcatt cggcccgatt
    28681 ggtatcgaca aaacaaaaga taattacgga tacgttttgg caactcccaa aaaagggtgg
    28741 gcacaattcg attttcttgg cacaatcaag gaacgctaca atattcctgc tgcttggaca
    28801 acggatgtca atgctgctgc atatggggaa ttgaagcaag gagcagcaca aggaaaaaat
    28861 agttgtattt accttaccgt gggaacagga atcggtgcag gtgtcgtgat caatgaagaa
    28921 attttttcag ggatcgcaca tcctgaaatg ggacatattt gggtgaaacg ccatccagat
    28981 gaccattatg aaggtacttg tccttatcat aaagattgtt tagaaggatt agcagcagga
    29041 ccgtctattg aggcacgcac agggatcaaa gggcaagatc tgccgcaaga tcatcctgtt
    29101 tgggctattc aggcttatta tattgctcaa gcactgatca actatacgtt gacgttagca
    29161 cctgaaaaga ttattttagg cggtggggta atgaatcagg atcatctcct tcaaaaaatc
    29221 cgtcagcaat ttgttgaatt gatgggtggt tatatggaaa cacctcaagt aagtgaatat
    29281 atcgttcgtt ggggactgcc gaatgaaagt gggattatcg gtagtttgct gttagcagaa
    29341 cacgaacatc aaaagtaagc agacaaatta cacaaaaaga acagagtctt atcattatct
    29401 gctgataaga ctctgttctt ttttatttct attcccataa tccaggtaaa gctttaccga
    29461 ctattttttc ttgagtaaat ggatggatca tgtgcagttc taatgcatgg agcatcagtc
    29521 gttcagctgt tctattttgg tagagagggt ctccaacgat cggatgtccc ttatgagcta
    29581 aatgaactct gatctggtgt gtacgtccgg tttccaaaac acaatagact tgtgtttgtt
    29641 cagaaagtac tttgttgaca gtgacatgtg tcaaggcgct ctgaccattt ttatcatcta
    29701 cgaccctttt tctccgatca tggcgatctc gtccaatttt attggtgatg gtcatatctt
    29761 tggcaatttc tccccatacg atggcttgat atctccgata gatcattttt tgttccaaca
    29821 ttcttccaag tatcggcaag acaaatggat tttttgcaaa taaaacggca ccgcttgttt
    29881 ctttgtccaa gcggtggaca acgtaaggtc gttgctgttt agtgtcgaga taagcagcta
    29941 aatgattgag taaggtactg ttttctgtcg gttcatttgg atgagtcttc attcctgcag
    30001 gcttatccac tataatcaaa tgctcatctt catataaaac acggatgtgc ttcgcatctc
    30061 ctaattgaac ttcttgataa ttataatctg tttcttcgaa taacaatgtg atctggtcat
    30121 tgccctttac ttcatgatgg aacaaagcag gttgttgatt gatccaaacg tttttacgta
    30181 tacgcaaaaa gtgtcgaacc tttctaggaa ctaaccattc cttttcaagc aagtcgcgaa
    30241 ttgttgtttc aggatggttc ataggtaaag tgatcgtgat tttcacaagt gtactccttt
    30301 cagtgcaatt gcagactaat tgtaccattt ttaaaacata tttaagaaaa aacttacatt
    30361 tttctgttca ttcttatgtt actctacttg cactaacgta aaaaaacata ttgaactaca
    30421 acttaagcag gaagaaaaca ctctttcact atggtaaaat aagacgattg aatcaaatag
    30481 acaggagaag aagcaaatgg attttcaaag cattttagaa aagataaaag ctgctttgat
    30541 cagtttttgg cgttggatca gaccatatct cggacaattc catcgatggc gaaagcgcat
    30601 ctggaaaaaa tatcatgtga acaaattgat tttgctgatt ggtttgatct gtgtcttagt
    30661 gacaagtatc tacctcttta ttttagcaaa acaagcaaat gtcgaaacgt taaaatcagg
    30721 attaagccaa tcgacagtca tttatgataa gaaaaacgaa gaagctggca cactgtacgc
    30781 ccaaaaagga acatatgtag aattaaacgc gatttctccc tatatccaag atgcagtaat
    30841 ctcgacagaa gataggaatt tttacgagca tcacgggttt gatatcaaag ggattgcccg
    30901 tgcagcagtc cgaatggtct tgtctggcgg aacatcaggg ggcggaggaa gtacgatcac
    30961 tcagcagctt gccaaaaatg cgtatctgac attagaccaa acgtttgatc gaaaagcgaa
    31021 ggaattattt ttggcaatcg agatcgaaaa gaagtacagc aaagaagaaa tcttgaccat
    31081 gtatcttaac aatgcctatt ttggcaacgg ggtatggggt gtccaagacg cttccagaaa
    31141 gtattttgga gtagatgcaa cgaatgttac gctgtctgag gctgctactt tggcaggaat
    31201 gctgaaaggt cctggtattt ataatccgat cgatcaccca aaaaatgcga atgatcggaa
    31261 aaacacagta ctaagtgtaa tggaagaaaa cggaaaaatc acaaaagaac aagaacaagc
    31321 agaaagccag acagatatca gcgcgtatct taatgacaca tacgataatt cagattctgg
    31381 ttatcgttat ccttattatt ttgatgcagt gatcgatgaa gcagttaacg agtatggtct
    31441 tgatgaagaa gatgtcatga ataaaggcta taaaatctat acagctttag atcaggatta
    31501 tcaaaagcaa ttagaagcta cttatcaaaa cagtgcatta ttcccagcaa atgcttcaga
    31561 tggtgccatg gtccaatctg cttcagtagc tttagatccg aatacaggtg gtgtacaagc
    31621 actagtagga cgaagaggag atcatgtctt tagaggattc agctttgcta cacagatgcg
    31681 tcgttcacca ggatcaacga tcaaaccatt aagcgtatat acaccagcac tggaagctgg
    31741 atacaagcct tccagtatct tgaaagacga accgcaaagt tattacgatg cgcataattt
    31801 tgacgggaca taccaaggag aagtaccgat gtatcaagct gttgcacaaa gtttgaattt
    31861 gcctgctgta tggcttttgc atgagatcgg tttacaaaaa ggatatgata aagcagaaga
    31921 attcggcctg cctttagcaa aatctgataa gtattatggc ttagcccttg gtggactgga
    31981 aaaaggagta tctccattga tcatggcggg tgcttacagt gcatttgcca atgatggtca
    32041 gatgtatacg ccgcatctta tcacgaaaat cgttgattcg actggagcgg tgatcgtcga
    32101 taacacaaac aaaaaaccaa aacaggtcat atcaaaggaa acagccgatg aaatgaccag
    32161 catgcttctt ggtacatttt caaatggaac agcggctgct gcgaatcctg caggttatac
    32221 gatagcaggg aaaacaggaa ccacagaaac taatttcgat gccacaaaag caaatgacca
    32281 atggatgatc ggttacacgc cagacgtagt gatttcgaca tggatgggtt acgaagaatc
    32341 cagcaagctg cactatttgg aagggacaag tggaaatgtt gtcgggaaag tcttcaaatc
    32401 agcggcagaa ggcatccttc cgtatacttc aaaaacagga tttagtgtag cagatgccta
    32461 tgccacagga ggacaagtgg tagctgcaga tcaagttgga aacacaggaa attctaatgg
    32521 agagtctgga aattggcaag ataacttgaa tcaatatggt gaacaagcaa aagaagggct
    32581 gaaaaacttc ggcgatatgg tgaaagaagg cgttcaggga attggtgaag cggctaaaga
    32641 cctctggcgg aaatatcaag gagagtagcc cctttgaaaa cgaataaccc catgttacaa
    32701 tagagagtaa ctactaaaag aaaagagggc ataacatgtc aaacatctac gatagcgcga
    32761 atcaaatcga acgtgagatc cgtgaattac cagaattcaa agcgttgaaa gaagcgtacg
    32821 agaaagtaca agcaaacgaa gaagcacaca aactgttcaa agacttccaa gcgatgcaaa
    32881 tcgaattaca agaaaaacaa atgagtggac aagagttcag cgacgaagat gcaatgaaag
    32941 cacaagaaat ggctgtgaaa atccaatcag aagaagtaat caatgacttg atgcaaaaag
    33001 agcaaggctt cagtacaatc atcaatgact tgaaccgtat catcatgaca ccagttcgcg
    33061 acctttacag cgaataaaac tattttatga aacaacagag ggtgtgaaag agacgttcgg
    33121 ccttgagcga tgacaaaatt gcttcttatt gccgataggc tgtctcttga acaccattta
    33181 ccaagaggtc gtgagcctac cgtttaactc tgagttacaa ggaacaattt caaaaaacag
    33241 cttctcatgt ttgatgacta ttgtgacttg tgaccgagga gttggcagga gaacaccgtt
    33301 tattcagaaa taggagctac gacaaaagtc ttgtcatagc tcctattttt tgtcattcat
    33361 ttttcaagcg gtagaaatag cctttttgag ctaacagttt ttcgtaagta cctatttcaa
    33421 cgatttttcc ttcatcgatc acaacgattt tatctgcctc tttgatcgtt gaaagccgat
    33481 gagccacaat aaaagtagtg ggtgtttctg tcaggtaatt cagggcttgc tggatttttt
    33541 tctctgactg gttatctaaa gctgaggttg cttcatctag caaaatgatt tttggctgac
    33601 gtatcaacgc tcgtgcaatg gagatacatt gcttttggcc accagacagc ttgttgccat
    33661 gttcgcctac taaggtatcc agaccatcag gaagctggtc aatcagtgaa gaaagttgcg
    33721 cagcttcgat gacttcatct aaacgttctt ttgatacgtt tttcaagcca taagtgatgt
    33781 tctctttgat cgaagcggag aacaacaaag tggtttgagg aacaacggct aaataatttc
    33841 gcacacttcg catatccagt tcatccaaag gctgatcatc tagaaaaatt tttcctgaag
    33901 tcggctggat aaatccaatc aataagttaa ggagtgtaga ttttccagag ccagatggcc
    33961 caacaaaagc aattgtttct ccagctttca cctctagaga aaaatgatcg ataatcggtt
    34021 tgagtgagtc cggataaaga aaagaaacat cctcaaaacg aaaatttcca tccaaatgtt
    34081 ggattttttt cttaccgtga taagtttcta catcgccagc aatcaacagt tcgccaatag
    34141 aagtgataga ttccatgcct tttgaaatcg taggaatcag cgtgatcatt ccagaaacgg
    34201 aattgacgat cgtcgtgaaa tacgtctgat acatcacgac atcgccgggt tggatgcgcc
    34261 cttgtaaagc taatatccca gtgaaactca aacaaatcag ctgaaatatc tgaaaactag
    34321 cccagctgac tgatccgaaa acagattgca ggatatctaa gtggaatcct ttttcataga
    34381 tttgagtaaa atgcttattt aagcgagttg tttcgtgttt ttctaaccca tgagctcgag
    34441 caatcggtgc taattcgatc acttcgatca cttttgcaga agtctcttcc atttcttgcc
    34501 tgaagtctga gttggactgt ctgatccttt tacggaaaaa gagagtaacg aatgcggcga
    34561 gaggaacagt caataagaaa aacatgaaaa caacaggact tttataaagc gtgataccta
    34621 aagctacgaa taaattgaca gcgatattta atccgctgac aaatacttga gaggacaacg
    34681 tttggatagc ttctacatca cggatgatct ttgactggat tcgtccagat tgcaattctt
    34741 tttgataagg aatagatagt tcttggattt tcttgataag ggtcgctctt agtccagctt
    34801 ctacttgacg gatcgaagtg ctatggtatt ttacatgaaa ataattcgtc aatatatttt
    34861 gaccaatcag acaagccatc aaaaaagcgt tgaaataaat ggcctgcaac tgagaagaat
    34921 ctttcgatga agctgcattg attacattgg caatagcgat cggcattaac caagatggaa
    34981 gatgtttgat aataaaaaag agtcctgaca tggcaaaacg ccaataattt ccctgataaa
    35041 gatgcagcaa tgtctgaaaa gcatttgcat gatatttttg ataacttttc tgtattcgtt
    35101 cctccataat cttctcctta acaatcttgg taaataaact gcaagtgttc tattgcttca
    35161 ggaacataaa tctcaggagt agcttcaaga gtggcgtaca ttagaggacg ctcatatttg
    35221 atataatgca gtaccgggcg gaaatctaaa cagcccttgc caacaggtac catgcggatc
    35281 tttccatttt ccatgatata gtctttgaga tgaagcgctg taatataacc atgtaaattg
    35341 tccaaggcac ctcggatcac tttttcctga tcagcatgat tttctttatg catcaaattc
    35401 gcacaatcta aaatgatttt taaatttggt gaagctactt catcgattaa acgtttagct
    35461 aactgatagt tatagattgg atgattgatc cctgcttcaa cagcaacagt tacgccaaaa
    35521 ttttctgcat gagcgactaa ttcaatgata gaatttctgg cgatctgata agcttcttca
    35581 gtaaaatttt cttttgtgta accgacagag acactaccgg tttccgtagc aatcatcttg
    35641 gcttgatagg cagagcacag agcaatttgc tgtttgaaag ttgccaatgc ttgtgcacga
    35701 acttcttgat ttttgctgga taggttgata tagcatccta aaatggaaag ttcgatattg
    35761 tttttttgga agtattcacc aaaataggca gcactcccaa gtgtcatgtc agttaattta
    35821 agttgttcag gaaatgcttt ttgtggtgca aattggatat gggacaagtg aagctgtgat
    35881 actttttgaa cgatttcttc acgatttcga acatctaaat cgtgggcacg gatgcctaaa
    35941 tttaatggaa acatctcaaa ctcctttttg taaataatta gcaagaggca gacgggattc
    36001 ttttatcaat tcaacaatta ttcgggcaac tttatcagcg ccttctggac taaagtgggt
    36061 attgtctttt agtccttctg ggtaattttt acaagtatca ggcataagat gcaggtagaa
    36121 tttttttgtc tcttcttttg agaaggtctg gaacaattct tgtgatcttg agaacacatc
    36181 taaaagagga atatggtgtt tctcagcaaa tgcacgcatc gcttttggat agtctccaag
    36241 tatatctgga ttcaatgttc cgttttctaa gtaatctcgt cgcgtcacag atgtcagtaa
    36301 gaccatttgg acgttcgctt tttttgcgca ttcaaaaaat atctgcagat tttttaaata
    36361 gctaccgaag ggaagcgtac ctctttcttc ttggattttc tggtcgttat gtccaaattg
    36421 tacaaataag aaatcattcg gctgaaactg tgaagctaga cgggctaacc ttccttcctg
    36481 gataaatgat ttggtgctgc gtccattctt tgcttggtta ttgatctgga tctcgggtga
    36541 aaaataagca gagatttttt ctccccaacc tgtctcggga cgcttgtttt catctttttc
    36601 tgccgcagta gaatcaccgg caatatggat agtaggcatg ttatctcttc tttcataaag
    36661 gtttataggc aatgaagcag aacagcaaga gaagaagacg gagcaa
//
LOCUS       DAPBAF010000030        35955 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.030, whole genome shotgun sequence.
ACCESSION   DAPBAF010000030 DAPBAF010000000
VERSION     DAPBAF010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 35955)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35955)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35955
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.030"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(16..2568)
                     /locus_tag="RD451_001688"
     CDS             complement(16..2568)
                     /locus_tag="RD451_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HDT7566949.1"
                     /translation="MNWYRLTVEDVLKNYQTSTEGLSQEERQKRLTDQGYNEIKARQQ
                     TKRWKKIAKHFTDLLMIVLIIASFLKFASSEYIEGSIILFVVIVNGLVSYWQERKAEE
                     SLNGLKQLMGQEAIVLSNGMQEKIPAKELVKGDVIVLRAGDVVPADIRLIEAHDLLVE
                     ESILTGESEASEKSHAVLTEEESIGDQKNMGFSGTLVQSGSAVGVVVETGNTTEIGKI
                     NQALQSVEQQTTPLIKKINRLNKQIFQGILCLSLFLVIFTTFRYGMDWHILLSATIAL
                     VVSMVPEGLPAVLTMILSVGVHEMAKEKAIIKGLPSVETLGSMTVICSDKTGTLTKNE
                     MTVVDVAAKEEACVLSIMKNCQELKTKEEQKTENLSGNPTEVALIRHTETANLPLKKI
                     EAKIPFSSEYKYMATMHAEEKGAVIYVKGAPEVLFAKSTLSSAEQEAWSQTAAEFARK
                     GQRVLGFAYKKVDSKQELTHETLTQLTFAGIAGLIDPPKESAVKAVKECQQAGISVKM
                     ITGDHKDTAKAIAEQIGLKHTAKVLEGIDLDLMSDEELIQQVPIVDVFARTTPEHKLR
                     IVKALQKNGEIVGMTGDGVNDAPALKRSDVGIAMGIKGSEVSKQAADMVLGDDNFHTI
                     AKAVKEGRRILDNLQKTINFFLPTALAQGLILIWALMLNRPLPLSPVQILWVNMVTTI
                     TLSYALGFESPDPEIMKRPPRDPKQGILSGYHLFRIIYVSLLIMVPAYLLAMQFEGQS
                     LQQTILLQNIVLAQAVYMINCRELSKPSLNQGLLQNKALFLSLGILALLQGMVIFLPV
                     GQQLIGTVSLTMTQQLLIGANVILLFLVVEIEKGIMNKLFRKKEKTAREYSR"
     gene            complement(2682..4013)
                     /locus_tag="RD451_001689"
     CDS             complement(2682..4013)
                     /locus_tag="RD451_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDT7566950.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRAMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKENFGQIDELLPFGFAGMVVSFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKKAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQGGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFAGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            complement(3979..5457)
                     /locus_tag="RD451_001690"
     CDS             complement(3979..5457)
                     /locus_tag="RD451_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDT7566951.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLENPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            complement(5762..7597)
                     /gene="tdc"
                     /locus_tag="RD451_001691"
     CDS             complement(5762..7597)
                     /gene="tdc"
                     /locus_tag="RD451_001691"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HDT7566952.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEKVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     GQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKKIAKAMEKKLNEIIQ"
     gene            8067..9494
                     /locus_tag="RD451_001692"
     CDS             8067..9494
                     /locus_tag="RD451_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7566953.1"
                     /translation="MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSNLLHVCKTTLLN
                     DINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLSQNSLFLKTCLLYLEEDE
                     PDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPRFTEMERRLLLLNVSYRL
                     GGFNSWELPESFFERADRFIESVTENSGRFYDKENKEILSIGFAISFLRQQVCAVTID
                     SKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDF
                     QQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKF
                     YLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYI
                     VTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDA
                     VQYENIIPISINTIDRAIISAVQNK"
     gene            complement(9586..9951)
                     /locus_tag="RD451_001693"
     CDS             complement(9586..9951)
                     /locus_tag="RD451_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HDT7566954.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(9948..10313)
                     /locus_tag="RD451_001694"
     CDS             complement(9948..10313)
                     /locus_tag="RD451_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HDT7566955.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(10505..10753)
                     /locus_tag="RD451_001695"
     CDS             complement(10505..10753)
                     /locus_tag="RD451_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566956.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            10752..10880
                     /locus_tag="RD451_001696"
     CDS             10752..10880
                     /locus_tag="RD451_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HDT7566957.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            10937..12631
                     /locus_tag="RD451_001697"
     CDS             10937..12631
                     /locus_tag="RD451_001697"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HDT7566958.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKITNTLTQ
                     EEEYVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            12635..12754
                     /locus_tag="RD451_001698"
                     /pseudo
     CDS             12635..12754
                     /locus_tag="RD451_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349726.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
     gene            12731..12904
                     /locus_tag="RD451_001699"
     CDS             12731..12904
                     /locus_tag="RD451_001699"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566959.1"
                     /translation="MQAFEHRLPRGYEKAALHQVIRAAKLKQLLMFLTWLDLLPQMQA
                     FEHRLPRGYEKGV"
     gene            13282..14415
                     /locus_tag="RD451_001700"
     CDS             13282..14415
                     /locus_tag="RD451_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HDT7566960.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYA
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            14446..14766
                     /locus_tag="RD451_001701"
     CDS             14446..14766
                     /locus_tag="RD451_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YrhK family protein"
                     /protein_id="HDT7566961.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
     gene            complement(14795..15259)
                     /locus_tag="RD451_001702"
     CDS             complement(14795..15259)
                     /locus_tag="RD451_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7566962.1"
                     /translation="MVTYNWIKLREHPELVKQSANWFSSKWGVPAVVYEESIRTGIAN
                     KESIPQWYVVLDEKETIVGGAGVIENDFHNRPDLTPNLCALFVEPEKRKQGIAKRILA
                     EIRKEMHQLGYEKLYLITDHTTFYERYEWTFLTMVKEESGTTARLYQSDTIG"
     gene            complement(15391..16644)
                     /locus_tag="RD451_001703"
     CDS             complement(15391..16644)
                     /locus_tag="RD451_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDT7566963.1"
                     /translation="MDKFVAFMEKHFIPVASKIGAQRHLVAIRDSFMVSMPLMILGAL
                     AVMINNLPIPGFQELMNSIFGGESWKGFGAAAWNGTFAILSVLIAFLLAYHLANGYRK
                     DGVSAGVISLGSFFALGGALGMSSNGLFIAIIVGIISTEIFVRLSGNEKLIIKMPDGV
                     PPAVAKAFASLLPAMITISAFALVAAIFAAFGVDDIVGSFYTVVQEPFMGLANSYPSA
                     LLLAFITPFLWFFGLHGANMVDPLMQTINAPAIEANVNAIAAGHSAPFIVNKPFFDSF
                     VNLGGTGATLGLLLAIYLVGRKNKPYMVVTNLSIAPGVFNINEPTMFGLPIVLNPIMF
                     IPFILTPMVLVSVAYFATSTGLVPAATVMPPWVTPPIIGGVLATKSIAGGVLAAVNLV
                     LSILIYLPFVKVATIQERRKEALDA"
     gene            complement(16673..16990)
                     /locus_tag="RD451_001704"
     CDS             complement(16673..16990)
                     /locus_tag="RD451_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDT7566964.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIIDLYRR
                     LNA"
     gene            complement(17016..17336)
                     /locus_tag="RD451_001705"
     CDS             complement(17016..17336)
                     /locus_tag="RD451_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDT7566965.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDVINMADYGMMNGEKVLDQAEK
                     LINK"
     gene            complement(17800..19215)
                     /locus_tag="RD451_001706"
     CDS             complement(17800..19215)
                     /locus_tag="RD451_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDT7566966.1"
                     /translation="MKITIPKNFILGAASSAWQTEGWKGKKEGQDSFIDSWYKNEHFV
                     WHNGYGPAVATNFMEQYQQDVDLMKSIHLTHYRTSINWARFFTDYENCIVDEEYAQHI
                     SEMIDSLIEADVEPMICLEHYEVPAFLLEKYDGWSSRKVVDFYAKYAQIAFDRYGDRV
                     KNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNYHKVLATAKAVEIYRSGNYGGR
                     IGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDPMVKGYYTEEFLELCQKQSIYF
                     DPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNEETPFHPERYYEVFDLPGKKMN
                     NSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGREYEEQYMDEKGIVQDDYRIEF
                     IGQHLHYLIKATEEGANCEGYMLWAFTDCVSPMNAFKNRYGLVRIELNDERSRTLKKS
                     ASWYQTLIDKRELDLPDEIYK"
     gene            complement(19232..20548)
                     /locus_tag="RD451_001707"
     CDS             complement(19232..20548)
                     /locus_tag="RD451_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDT7566967.1"
                     /translation="MRGSGMSFMDKLANVLGNVATRINNLRYIMVIKNAFAALIPVII
                     TGAFGTLFSAMVFDSENGLAQISFLRFLEELKPIASAISYVTLSFLTIYAVFLIGIEL
                     AKLNKVDGVFPGIIAVMSYLSVNPTVYELVNENQTVIVENVLAKQYTDTKGLFLGMLV
                     SILSIELYCWLRKQKKLQLRMPDTVPTNVSASFSALFPTILTVSGIAAAGFIIKELTG
                     MYLYDIIYNVVQRPLEGVVQGLPGILLLMFIAQVFWVIGIHGNQMVKPIREPLLLAAI
                     AVNTEAFEAGKEVPNIITMPFWDMYMSMGGSGVTIGLLIAVLLVGKREDMKQITKLSL
                     APGIFNINEPVIFGMPIMLNPILAIPFILTPLITGTIGYFATALGFAAKAVVMVPWPM
                     PPIVNAYLATAGNIGAVITQLVCIIVSILIYLPFVKVANRVENDGI"
     gene            complement(20698..21396)
                     /locus_tag="RD451_001708"
     CDS             complement(20698..21396)
                     /locus_tag="RD451_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HDT7566968.1"
                     /translation="MEENKTLVEVTTDKILRYLKEMQLQVGDKLPNEYELSDYLEVGR
                     STVREAVRALASRNILEVRQGAGTFVSDKRGIANDPLGFSLIEDQDRMIRDLFELRYL
                     LEPKMAGLAAEYATKNQIVQMKKLTQKIETSFREGTQEHVQLDIDFHTMIAEASGNVA
                     LLHIIPIINESIALFNKNYDIQHLKIETIDIHTEIVQAIERRNALAAFDAMTVHMAIN
                     RRELQKIIGEKETN"
     gene            complement(21685..22641)
                     /locus_tag="RD451_001709"
     CDS             complement(21685..22641)
                     /locus_tag="RD451_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HDT7566969.1"
                     /translation="MEYRKSGHSGLKLPILSLGLWQNFGDYDPIHNQREILRGAFDMG
                     ITHFDLANNYGGPAGAAEKNFGRIFREDFQAYRDELIISSKAGYHMWEGPYGEWGSRK
                     SIISSCDQSLQRMGLDYVDIFYHHRPDPDTPLEETAEALMQLVRQGKALYIGISNYNG
                     EDTKKMTEILKRKEAPFIIHQMRYNMFSRALLEDDLSPVLEEEGLGAITFSPLAQGLL
                     TNRYLHGIPEDSRAHRKEIPFLSEEQVGSTLEKIKALQTIAVSRGQSLAQMALAWNLR
                     QKSVTSVLVGASRLSQLQESVRMMDNLDFSPEEELRIDQILE"
     gene            complement(22754..23587)
                     /gene="msrA"
                     /locus_tag="RD451_001710"
     CDS             complement(22754..23587)
                     /gene="msrA"
                     /locus_tag="RD451_001710"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HDT7566970.1"
                     /translation="MDEEQIFIQTLYNLILNPNTRDWERKVLIQTKNDIRENISVKEQ
                     LSKLEATLRPLAIRMNLTPDVMDFYLLITEGFDKEQKYDFSKHAMQDADYQERAVFAG
                     GCFWCMVEPFESKKGILSVLSGYTGGHVEKPNYDQVSGGYTGHVEAVEIIYDTREISY
                     SELLTIYWQITDPTDTFGQFQDRGKQYRPVIFYQVERQKELAEQSKQKLDSSGTFHQP
                     IVTKIEPAGTFWPAENYHQQFYKKQPKRYKKIQQARNQFLIYQRVKNKWQKNIRKNHF
                     D"
     gene            complement(23762..25396)
                     /locus_tag="RD451_001711"
     CDS             complement(23762..25396)
                     /locus_tag="RD451_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566971.1"
                     /translation="MKINKKVVILSGLIIVSSIYSFIFFKNTQSIYTTGDLSFHLSRI
                     KGLSTIFTSPINYETFNYTGYGVNYFYPFLTFFPAVMLYWMTKNLIVSYIIYVWLLNL
                     CTTLVAYHYGERFLKQKKAAFLFSCLYIFSAYRTVDIYYRSAIAEAIAITLVIPVLFY
                     AYQIISGKEEKYPSVKLALSMSLLVYSHVLSTLMSTALIIIFIFIRLVSKGFKNADFI
                     AIFKKLFSAAGMTLVLTSAFWYPMFEQMLYQKINKPSVTNLYAHASNVFDSLTEAMNN
                     DLTTYSMGLVGLLSLCIPLILFKKLTNIEKKIYYGTCLTWLATTSLVPWYLLQNTPAK
                     LLQFPWRILSLQIIFSSLILTMIFFKNRRYNKTRELFYLFMTVLLLITLTVSSKKNFN
                     QKIISQPGHIVVNKETVEAYTTKGMDYFLYDYSPIASLENKEHIIKHEAKIGSQWVNL
                     PYKTTGSSIIYRVTNEKSQVITLPVYAYLGTNVEINHQPVKEQVNANGLVQISGVKGV
                     ADIKVSTSYTVTTIISYLVTLTAYLCLFFKIVFHKR"
     gene            complement(25383..27251)
                     /locus_tag="RD451_001712"
     CDS             complement(25383..27251)
                     /locus_tag="RD451_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566972.1"
                     /translation="MISIIWFLFFFIFFSYLKVIKIDSFLVYHTSAMKNLTQNLLKKD
                     NSSILKIELKKENNKSMKISKKAFLLVVLILLSTLYSVNFMRNAQEIYTTGDLSFHLS
                     RIKGLSSIFEGPINYTTFNNYGDGLNYFYPFLTIIPAVVFYGISNNLILSYVLYIWLL
                     NICTILISFYYGEKFFKKIDAAFLFSCLYTFATYRTVDIYYRSAIAEAIALTIIPAVL
                     YYAYGLIFNREKKVIALSVSISLLVYTHVLTTLLCSALIACMIIVRLFLSKQIKNDIK
                     FVVVNLVKAVFLTCALTSYFWYPMLQQMNYQEIHSPFKTDLQLEALSISDSIIQALNN
                     DITTYTMGLLGLVALIFPLFILKEMEKKEKIIYVGVVSTWVCVTNLFPWFLFQKTPIS
                     LLQFPWRILGIQIFFSSMIITLVFMKKTMNKKYSWLIIGATVVFLLVTSIAAKENYAK
                     VIQSKHGHIVINEETLPRYTTSDMGGLYDYAPTEAIKERPHLEKHEVKVGESWEKGKY
                     KAADNNITYTVASNKKQKVTVPVYAYLGTQVKVNGKVVNDSYKKHGLVNVDVNAGENK
                     IEITTKYTPTALMALWISILTYCLVVYSSFKRFAPNKLKDSRYVTKKEINKKNENK"
     gene            27217..28854
                     /locus_tag="RD451_001713"
     CDS             27217..28854
                     /locus_tag="RD451_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566973.1"
                     /translation="MKKNKNQIIDIIFMLFLSFAYVIPLFMSKGIYHSVNQDTYFHLS
                     RIIGLDNVWSSPVNFNNFDHHGTMMNIFYPWLTLYPAFLFYKMMGNLVLSYNIYYFFI
                     TFLTMVVSYFSMKQIKNNRYISLLFSIIYTFSAYRAIDIFHRASLGEAVALTFLPLIL
                     MGCYEIYIRDYQKWYWLSIGMTLVVYTHLLSVAMVSVFIGGTLFLSFYFWDQKIARLL
                     SLLKATVLTFFLSAGFLIPFIQQSRAQELKVPLGKELSGMAPSDMLTHILNNNYNNYT
                     IGLFLFLGLIGAFIFIKKLTADDLFIFFLGVFVLFCSTNLFPWQLFNHTPVKSLQFVW
                     RLNGFSSLFIAYTMSIVIYYIFSTKNNSWKIMVFTFLALILHLSGVSNSIHANKDSLT
                     LIAPEDAVAIAENYNHTDYANKESIYHPDMINNDQYLLGNQEINPTTHFMSNKLTIEL
                     DNSNNKNTVLTTPIYRYKGQVASINGKLVQTKLSKFGTTELTIPPGINKVVITYQYTK
                     LAIASRYLSIVTLILFLLYRFTFSKQKQPRREVQHSH"
     gene            complement(28999..29739)
                     /gene="truA"
                     /locus_tag="RD451_001714"
     CDS             complement(28999..29739)
                     /gene="truA"
                     /locus_tag="RD451_001714"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HDT7566974.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYR"
     gene            complement(29930..30565)
                     /locus_tag="RD451_001715"
     CDS             complement(29930..30565)
                     /locus_tag="RD451_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HDT7566975.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIAWLSILHLKQ"
     gene            complement(30712..31953)
                     /gene="sstT"
                     /locus_tag="RD451_001716"
     CDS             complement(30712..31953)
                     /gene="sstT"
                     /locus_tag="RD451_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HDT7566976.1"
                     /translation="MLEKFLDMSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSC
                     LKAIAPILVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPIT
                     LQETVSEKAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSEST
                     KELVDQISIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLF
                     VALVVYPFLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKE
                     SYSISIPLGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGV
                     AGGSLLLIPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELG
                     ARKRSGEKIKLKDCLDGLSER"
     gene            32151..33149
                     /locus_tag="RD451_001717"
     CDS             32151..33149
                     /locus_tag="RD451_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566977.1"
                     /translation="MFLSNFFVRCLFLKKIKKESYGFLTIFVACIMMVLQRILISAVT
                     IPTYATNPGRFYIYTFLQTSVVIGANLIPLYMGYQYQKIARLKVLHYLSRFAFIFLIA
                     TLVCNIFFYVQAGSLNIRDYWLILTPISQNYFTYAVSCTLLFCSIPYTVGFLNKLSKT
                     TIKYLLLFLTIGLVGCSTLFNKDPFALQNGQSILWIFYLFLMGYGLKEWNWKEKVRYK
                     LPQVFISLIVLFGLIILMTQISLIIRGNTDTALRFSKPYSLFAMYYTFSSFLFLEMLS
                     DKLGIKGRGNFLAVFLIVTQVICNFPLVSYRVSTFMKREFPNSGKAWLINIGQFFI"
     gene            33162..35180
                     /locus_tag="RD451_001718"
     CDS             33162..35180
                     /locus_tag="RD451_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HDT7566978.1"
                     /translation="MSLLVIFLFYIQKIRFIHRFIEYFAFDSIEQLTQRWKKRIHWLF
                     VHKSYFLVAAFFYCFTFVQIFVLEPKEGWKETIQVALKIFTQRQAPMILTIIIIMGFF
                     FLLLLISNRFWYALTATLIINLLLTISTVIKMEMREEPVFPSDLKMLTGLSELLSMVS
                     PVLLIVGGLILLLLLITSIIVQRRLQKQYSLKIHWKRRFISIAVLLGCFSGVFFINHK
                     NSPSFLLFNLFKVNKTFFNQQGAVKDNGPVIQFLNNIDIKIMEEPAGYSKEKINGIMK
                     KYNTKADEINQTRSDWLNNQTIVLNLSESFSDPARVPNLTVPTDPIPYIKSIITEGTG
                     GLMLSVGYGGGTANMEWEGLTGLSISNLSASLVTPYTQLVERQKISPNITDLFDEKIA
                     IHPFTAALYRRKQVFDKFGFDRFYYLDSPDKLTYTDKIEQSPRISDDSAYKETLKALQ
                     SNTETSQFIQLSTMQNHMPYDDYYSELNYTAEGTAVIPNRRKELQTYMQGLHYTDTAV
                     KKFIQEIDKIDKPITFVFYGDHLPAIYSGNDSKKYGLEQHQTDYFIYNNKYSREQAAT
                     LNKEVVAPNNFGAMALEHANIKVTPYYALLTEVSNHLPALTIDPTESLSNRFNGKQVF
                     VTEDSQIIQEKNLTEKQKEILEDYRLIQYDLVAGNQYSATWATQKIKD"
     gene            complement(35240..35932)
                     /locus_tag="RD451_001719"
     CDS             complement(35240..35932)
                     /locus_tag="RD451_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HDT7566979.1"
                     /translation="MGLAFLLAGCTNGNESKKESTKETAKATVATTTTTSTESKSTAA
                     STETADTSTSSESSKTTETTQTSTSSSSVEASSSSSESSEQVEQTLWNADKSAQLEAF
                     MTKWGQTMGQQYKSYTNQMSVDLYGLKVPQAILNGEWKMAIGGVPVSAEWSESGTGQA
                     DYQITAVYSDAETEPYLKKHVYLFGFQQNQPKVLVTQQNQGNPDNYLYFNETANNELK
                     NGFNQIVYGQAN"
BASE COUNT        11340 a         7120 c         5916 g        11579 t
ORIGIN      
        1 tttttatagt aacggctagc gactgtattc tctagctgtt ttttcttttt tgcgaaacag
       61 tttgttcatg atcccttttt ctatttctac aactaagaat agaagaatca catttgctcc
      121 aatcaataac tgttgtgtca tcgttaaact tactgtaccg atcagctgct ggccgactgg
      181 tagaaaaata accatccctt gcaataaagc aaggatacct aatgaaagaa aaagcgcttt
      241 gttttgcaaa agaccttggt tcaatgacgg cttggacaac tctctgcaat tgatcatgta
      301 aacagcttga gctaagacga tattttgcag aagaatggtt tgctgtaagc tttgcccttc
      361 aaactgcata gccaataaat aggcaggaac catgatcagt agggagacat agatgatccg
      421 aaacaaatga taaccagata ggattccttg ctttggatct cttggtgggc gcttcatgat
      481 ttctggatct ggcgactcga accctagtgc ataagataaa gtgattgtcg ttaccatatt
      541 gacccataaa atctgtactg gggacaaagg tagcgggcga ttcagcataa gtgcccaaat
      601 caagatcaat ccttgagcta atgcagttgg caagaagaaa ttgatggttt tttgcaaatt
      661 atccaaaatc cgccggccct cttttacggc ttttgcaatc gtatggaaat tatcatctcc
      721 taaaaccata tcagctgcct gtttgcttac ttcactacct ttgattccca tagcaattcc
      781 tacatcggat cttttcaaag caggtgcatc atttacgccg tctccggtca ttccgacgat
      841 ttctccattt ttctgcaaag ctttaacaat tcgcagttta tgttctggtg tcgttcgagc
      901 aaagacatcg actattggca cttgctgaat caactcttca tcagacataa gatccaaatc
      961 gatcccttct aaaactttgg cagtatgttt taagccaatt tgttccgcaa tcgcttttgc
     1021 tgtgtctttg tgatcccctg taatcatttt cactgagatc cctgcttgtt ggcattcctt
     1081 tacagctttg actgcacttt cttttggcgg atcgatcaat ccggcgatcc ctgcaaaagt
     1141 taattgggtt aaagtctcat gcgtgagttc ctgtttcgaa tctacttttt tataagcaaa
     1201 tcctaaaaca cgctgacctt ttctcgcaaa ttctgcagct gtctgactcc atgcttcttg
     1261 ttctgcagaa gaaagagttg atttagcaaa taatacttct ggtgcacctt tgacgtaaat
     1321 caccgctcct ttttcctccg catgcatcgt tgccatatat ttgtattcag aactgaacgg
     1381 aatctttgct tctatttttt tcaaaggtag attggctgtt tctgtgtgtc gaatcagcgc
     1441 aacttctgtc ggattgccac ttaaattttc tgttttctgt tcttcttttg tttttaattc
     1501 ctgacagttt ttcataatgg acaacacgca ggcttcttct tttgcagcta catccacaac
     1561 tgtcatttca ttttttgtca atgttcctgt cttatctgaa cagatcactg tcatagaacc
     1621 taatgtttct accgaaggaa gtcctttgat gatcgccttt tcttttgcca tttcatgtac
     1681 tccaacggat agaatcatgg tcaaaacagc tggcaatcct tcgggtacca ttgacaccac
     1741 caaagcaatc gtagccgaaa gaaggatatg ccaatccata ccatatcgaa atgtcgtaaa
     1801 aataactaag aataggctca aacaaagaat gccttgaaaa atttgtttgt ttaatcggtt
     1861 gattttttta atcagaggcg tcgtttgttg ttcgaccgat tgcaatgctt gattgatttt
     1921 accgatttct gtcgtgtttc ctgtttctac aacgacaccg actgcagaac cagattgtac
     1981 aagcgttcct gaaaaaccca tatttttctg gtcgccgatc gattcttctt ctgtcaaaac
     2041 ggcatgactt ttttcagatg cttctgattc tcccgtcaaa atcgattctt ccactaataa
     2101 atcatgtgct tcgattaatc ggatatctgc tggaacgaca tctccggcac gtaagacaat
     2161 gacatctcct tttaccagtt ctttcgcagg gattttttct tgcatcccgt ttgatagtac
     2221 tatcgcttct tgtcccatca gctgcttcaa accattcaat gattcttccg cttttctttc
     2281 ttgccagtaa ctaacgagtc cattgacgat cactacgaat aaaataatac ttccttcaat
     2341 atattcacta gaagcaaatt tcaaaaaaga ggcaatgatc aacacgatca tcagcagatc
     2401 agtaaaatgc tttgctattt ttttccatcg ttttgtctgc tgccttgctt ttatttcatt
     2461 atatccttga tcagtcaggc gtttctgtcg ttcttcttgc gacaagcctt ctgttgatgt
     2521 ttgatagttt ttcaatacat cttctaccgt caatctgtac cagttcatcc tatcccctcc
     2581 tgtttaattg atactgttat tatacgcagg gaagtttttt caggcgtatc gattatttca
     2641 ggggggtctg aaataattcg ttttgcaaaa tgtatctggg cctaactgat atttctattg
     2701 cttattcttt tatatacaaa atttaagaat acaaaccaga taaccaataa aaaaggaata
     2761 aagcgtgtcg tgctttcgaa taacaagctg aaagcaattg aagtaaaaaa caccaacaaa
     2821 gcaagatctt tatatctttg tgtagtgttc cgtttctttt ctttaataaa ttgaacatgt
     2881 gcacacaaga tcgaagacca cacaaataga aaacaactcg ttgtcatgcc tgccaaaagc
     2941 tgaaaaaaca atcgactatc agctacaaaa aaatgtagac aaagaccggc aaaaaataac
     3001 attcctgtaa ttaaaatacc gtgtaaaggt acgcctttct tagaaagcgc acaaaaccaa
     3061 tggggcaaac ttttttcttt tgctgtttga tataaaatcc tgctagtact gtagactgca
     3121 ctatttgctg aggacaaaga agcaaccaaa atcattagat tgacaattgc tgctccgcct
     3181 tggcaatgga tcacttgcag catagtcact aaaggacttt cttttaaatc taaacaatgc
     3241 catggaacaa caaataaaat cgacaaaatc gttcctatat agaaaaagag aatacgccaa
     3301 ggcagacagt tgattgcttt tttcaaattc ttttgcggat cacttgtctc gccaacggtt
     3361 aagccgatca tttcaattcc agcaaaactg aataaaacca taggaaatga gactaccatt
     3421 ccagcaaagc caaacggtag taattcatcg atctgtccaa aattttcttt gattccgata
     3481 gactgggtat gaaaatctga gacactcaat cctataccca ataagataaa aaggaaaatc
     3541 cccaagatct tgatgattga gaaaaaagat tccaattcac caaaccactt gactgcaaca
     3601 aggttgactg ccattaagat cattagtgcg ctacctccgc ttatcaaagc tggtacatgt
     3661 acaaaccaga aatggatata caatcctatt gctgttaatt ccgcaagtcc agctccaagc
     3721 cagcaaagcc aataagtcca attgacaaaa aatgcccact ttttgcctaa ataatagtca
     3781 acgaaatcac tgatagagtt aaatgtacta tttgctaaaa ataaatcacc catggcccgc
     3841 atcaaaccat aaatagccaa accgcatatc aaataaacga gaataacagc tggccctgct
     3901 gatgcaattg cctttgctga acctaaaaat aatcctgttc caattgcgcc acctaatgcg
     3961 attaactgga tatttcgatt agttagagtc cgtttcattg ccggtttttc catcaagttc
     4021 acctttttct ttttcaagca gcatggcgac ttcctgttcc caagaaggtt tctttatttt
     4081 ttcaatacag agtggtacta caaacaaaat gacactgatg gctgtgactg caattagatt
     4141 gatccatgtt ccagctttca tcgtcagtcc gacagaaaat ccgattgccg caaataaaac
     4201 aataacgaca gtccaaactc caagattgct ctttttctct ttttttccaa ttctaaatgg
     4261 tcgattcaac tttgcatgtg tataacgcaa tctcaaaact gcgatcccca tgatgacata
     4321 gacgatacag tagataacag tagttgaatt tacgagcatc aaaaatgctt gattgacgcc
     4381 aggaatcagc aaataaaaaa gtgcaaagat tgagataatg acagactgag tcaaaataac
     4441 ggatttggat acgtcaaatt gattcgtctt ccaaaaattg aattttggtg gatacgcacc
     4501 ttttctagca ctttctgtca ctgtctttgc tggtcctgag gcccaagcag ataattggac
     4561 tgctacacca atgaagacaa gtaaactaaa cagattcaca ataagatgtg gcaaaccaag
     4621 aatttggcaa taaatcgaaa tagattgcgc gatattattc aattccattt gtccttttgg
     4681 tacgacattt gctacaacta aagcattcaa aatattgacg aaaaatataa aaattaacgc
     4741 ggcaaatact ccgcgaatat acgttttaac tggattttcc aatcgagtga tatacacaga
     4801 ggacatttcg ataccagtaa aaataaacat gatcggcgca aaataaacaa atgaggatgc
     4861 agtcgtagta tctggtatta atttgtccca tgaaaaactg cctaatgttc cggttggtac
     4921 gatcccaact ttgatccacg cagcaaaccc taataagagc atcatcgtca aaggcacgta
     4981 caatcctaac caaacaccga cttttccgcc gatttttgcc atatcaaatt tcaaattcaa
     5041 aaaagtgatg atccaataaa cgactaaaat gacaactaat gtaaatttgc tgttcaaacc
     5101 aagcggcaca ttatcgataa tattaccaaa caacggagcg agtgctgaag cgaccatcac
     5161 catcccagga aacatttgga cccataacag ccatgagaca acgaaccccc atttttttcc
     5221 tagagcattc gatacccaaa gttctggacc acctttttgg ggaaacattc cagcaaattc
     5281 accagagatc aatgagattg gaaaagcgta caataatact gcaaccagca tgtaaaaaat
     5341 catcgtccag ctcgttgctg ctacatctgg aatatttcgt acacttgcta caagggcgca
     5401 ggtcattccg ataaaggtca tggtcgtgat ttgctttgat gaaccagtat ctttcatctt
     5461 tattccttct ttcaatagcg acatatgttt ttgttttctt ttatttttgt tcaagaacag
     5521 aaatgacaag gtttcatcga ttcagtacaa aacccagtat caccgaaaca tccattgaac
     5581 gatcttagtg aactgggttt gatacatgaa acgaacgatc caacttatag aacgttttat
     5641 aaaaaagaat atcttggcga ggaatatatg aaaaacaggg ggaaatacaa ttgttttgat
     5701 gaagcaaata attgtctgtt ctccatatgt ctcttgttat tctttcacac aaaaatcagt
     5761 tctattggat gatttcgttt agtttctttt ccattgcttt ggcgattttt tttgtataaa
     5821 aattgaaaat tcgatcatca ttcaaataag gagtcatgat agccgcacgt agcagagtga
     5881 ttttctgttc ttttttccat tcttctttcg ttagacccat tctttcaaca aaacgaatcg
     5941 gagaatcacc gtaatcttct tgtgtaaatg tagtatgaga agtaataaac cgttcaccat
     6001 aaacatcgcc atccatataa gaagaccgat cgaacatttt ttcatttaat tcattgatag
     6061 cgttcaaatc tgtacagcct tgttctttga atacccaatt gaccatatta aaatcaggat
     6121 gattcaatgg atagacttcg attgtttttc ctttaacagt aaaagtcaga tgatcgagaa
     6181 attctctgaa tctttgagct gcctcgattg aagccccaat caattgacca tatccggtca
     6241 cattcaatgg caatacacga tgtgctgtcc agactgcggc ggcggttgct ccagcttttg
     6301 atccttccaa aatataagct cctaacatat ctggagcctt tactgatttt tcaaacacat
     6361 atggcgcgaa ataagaaatg atatttctca tatttttatg tttgattacg attcctccag
     6421 cagcataagg gacatagccc atcttatgag gatctatcgt gacagaatcc gcttctgaaa
     6481 tagctctgaa cccttcatat acctctttgt caatcgttac gcagtggtgg aaaacatgat
     6541 gttcttcaaa gaattcagct aaggaagcat acggcacaaa ttctcctgct tcgtttagaa
     6601 acagtgaacg cgcatagccg ccatatgcgg catcaacatg taaatagaaa tagatccctt
     6661 catcttttaa cctttctctt aattggacga ttttatctac actgtctact tgaccttctt
     6721 ctgtcgttcc tacgacagca accacaccta gaattgggat tttttgtcca gctaattcac
     6781 gaattgtttt ttccaaagca ttaatatcca ttcgataatc ctcttgaact gggatagcaa
     6841 ccatctgatc taagccgact ccgcaaatat ctaacgcctt catccaagaa tagtgttttg
     6901 tttgagggac cagccatttc cctaatcttt ggatattttt tccgctacgg gaagaagctg
     6961 ctttgacctc atccatttct tcgtccgtaa agctttcggt catttccaaa atttcttcaa
     7021 cagataaatt caaaagttcc cactcagaca tttttttcac tttttcaggc agcacttcct
     7081 tgacagctaa aggaatcgat ttgatgcaac gggcgtacca taatccttca agattagcaa
     7141 tagaaccatc tgctgcaatg tgtccccatc cgtctgtcat attgaataat gaagcaaaat
     7201 cctgtcctac ttctgcttcc atttgcgaag ttgccataga agattccaat gcaacattat
     7261 ttgggttcca cagcatcgca tagttgtaag ctaataaagc aggcatcaat gtttcagcat
     7321 tcatttgtcc ccagtaacgg cctgctgaat gccatgggat cgatcctgcg cgtaatcgct
     7381 gactgacttc atccaagacc tctatcatat ggtcgcgggt ggctagataa tctggagtga
     7441 gcttatctcc ttcgctaatt gcaggcatat ctgaaggaat ataattttct ctccatccaa
     7501 gatgttcatc taccatcttg ttcaacaaca ttttataaac tggtccattt tcagctttgt
     7561 cgcctataaa gacggccttg atatccatat ctttcatttt tcttccctcc atattttgtt
     7621 ggtcaatgtc ttgcagatac atgtgtttat ctgtaacacc tcttcactat agcgccaaaa
     7681 atgagaattt tttttttata acatcaaatc cacgtagatt tttacaaaca aaaataaata
     7741 aagtcggatt tttctgataa ttcaacgcaa aaaagcgaac aatttttcaa taaatcagtc
     7801 ttctaaaata gataacctaa aaaaagcgaa caaacaaata aaatgactgt ccttcattca
     7861 ctaaacatat ttttattttt ttatattgtt aaaaattcgc aatttatttt ttaatagaat
     7921 tatctgtttt ccaaatttta taacataaaa aacctttttt aacggcattt atatgctttt
     7981 tcagaaatta actgatgatt tcaaaaagaa aacatgtcat aatatttccc atattgtgca
     8041 aaaaaataca aggcggaggc tctactatga ttgaagaata tattgagaaa aatattttaa
     8101 gacagctgtt tttatgtggg caattctatg taaataaaga agtcaatcta gaaaagctct
     8161 ccaatctcct gcatgtttgc aaaaccactt tactcaatga tatcaataac ataaaaaaag
     8221 aatttgaaga acagatcgct tatacacatc gggaaaagga ccgttacact ttatattttt
     8281 cagaacatat acctcgatgc aagatcatgc agcaattgtc tcaaaattcg ttgtttttaa
     8341 aaacttgtct gctttatttg gaagaagatg aacctgatta tcttcaatta actgaatgtg
     8401 aattcatctc tgtcagcaaa gcttattcat taaaaaaaca agtattagct tattttaatg
     8461 actgcgggat cgaaatcgac cgctactccc ctcgattcac tgaaatggaa agacgtctgc
     8521 tgcttcttaa tgtgtcgtat cgtttaggcg gttttaattc ttgggagcta cctgaatcgt
     8581 tttttgaacg tgccgatcgt ttcattgaat ccgtaacgga aaatagtggc agattttatg
     8641 ataaagaaaa taaagaaatc ttatcgattg gttttgctat cagtttccta cgccagcaag
     8701 tgtgtgctgt gacaatagat tcaaaattta tcgaagaaat caaaaaacgt cctatttaca
     8761 attatgtcga atcagcatgg gaaaacactg atttccaaac ctattataaa aaagaagaat
     8821 tcgcctttat tttgacacta ttcaatcttt gtaattatgg tttccattct tatcagttga
     8881 ttgcggaaga ctttcaacag ctacaccaag tgtttattga caatactccc gaaataaaag
     8941 aactagttgc tacctttgaa tctcacttca atcaagaatt attcggaaac caaccgttcg
     9001 aacgtgcgct gattcatctg atgcgttcgg cttgggataa ctatcaatta ttcatgccag
     9061 aaaaatttta tcttttaaat gaggaacaga caaatttata taaagaagtc cagacaattt
     9121 tttccagctg gtccagccag ttaccttatg atctacggtt gaatcctaat tgcatgcggg
     9181 cttttgtgat cgaattgagc ggaattctcc gtctgacaaa agaacatctg actatctata
     9241 tcgtcacaaa ttcggatgtt cattatctga tttatcggga agccttggaa gctgtaacta
     9301 ctttcgattt tcaagttgca ccaacaattt attcaagtat atctgatata aagaagtatg
     9361 cgcagcagtc ctcaaaccgg gtattatgtg aacgtacatt atatacacca gatgcggtcc
     9421 aatatgaaaa tattattcct atttcgatca atacgatcga tcgagctatc atttcagctg
     9481 tgcaaaacaa ataaggggct gtgacaaaaa tcatgtcaca gcctcttatt tgttgaagat
     9541 gcccatttct gtaacaatct cttgatacac gtcaggctca caacctcact tattttggac
     9601 atctacgggt ccgatctctt tatttaaaaa ataagaaatg atggttcgga taactaccaa
     9661 cgccgctagt tggaaaatat cctgcaaggt aggtttgata atcgattcga tgatcccagc
     9721 tgaaacaaga atttccaaac ttagaagtat atagcctccc aacatctttt taatagcatt
     9781 gttctcgctg actcggtcgc tttgcacttt tgtatggaca aataaatatt tcaaaaaatc
     9841 cttgattgat agacaaacac cccaaaccaa taaacagata gcaaagatat caagtcccag
     9901 tacaagtttt tcgaaatatg gaagaagaaa ctgcatcaac tctgtcgtca tcctacctct
     9961 cctcttcttt gtttttcttt gtcttctatt tcctgattca agaaataaga aatgactgtt
    10021 cgaatgataa taataagtgc aagcttcaaa atatctgtcc aagtcggctt gataactgac
    10081 tcgatgatat cagcaacgac tagtacttcc aagcttaaca aaatataact tgctagcagt
    10141 tttcttgtat ctgcattacg agtattacgt tctgcatagt ttttcttgac atgagaccaa
    10201 tcaaaaagtt tgaatagaac aagaacgatc ccgacaatta agataccgat agaacaaata
    10261 tttaaaatag caatgatcca ttctagaaat tcaattaaat ttgagcgaaa catatacgct
    10321 acctactttc ttttaatttg ttcctattct tttattgtaa aagaaagtta ccttgttcgt
    10381 ctatttaaaa gttgttctaa tgataacggt tcgcttaaat ttttcttttt cactctccca
    10441 tttttctccc tccatccata aatcgtggaa gtatccaaaa caacgtagca agttaaaata
    10501 aggcttagtc cgtcatcagc ttttcaaaga agcactgtct cggtgctttt tttgtaccca
    10561 aatttctaaa aatagaacca tacacctcct caaatctttt cttcttacct accctatttt
    10621 tatttacagg aaaatcagac acttcttctt ttttgtcaaa atttcctttt tcttctcgtc
    10681 ctatcatttg gcattctaat aaaaacgaac tatccttgga tatagaaaga gaaaacaagg
    10741 aggcgttttt catgagtaaa aaattaatca aagtcggcat cggtttaggt ttgcttgccc
    10801 ttggcgctgc atatctagga aaaaagacag gactattcga agatgacagt catttatatg
    10861 atgaattcga atcaatctag catcctattt agttgaatca ctacggacat acttggaaga
    10921 cattggagga atcacaatga gaaaaagtaa agcaataatg attggtgccg gtattgccaa
    10981 tatggcagcg gctgtttatt tgattcaaga aggcaaatgg aaaggggatc agatcacctt
    11041 ttattcattg gatgatcacg gttcaaatga tggtgcaccg accgacactg tagtggatga
    11101 atattggaat aaaaaccatc cattagaaaa ccaaaaaggc tatattgctc gaggcggtcg
    11161 catgcttaat taccgtacct atgtagattt gatggatctg ttaagtcgaa taccttctgt
    11221 tactgagcca gggatgactg ctgaagaaga tacgagagat tttgatgcaa aacaccgaac
    11281 ctttgacaaa gcacgtttga tggaaggtgg caaaggaatc attgatggcg gaaaactggg
    11341 attcaataat aaagaccgta ttcttctgac taaactgatt gctatgcctg attcagaaga
    11401 agaaaaacta gacaatatca ctatcgaaga atatttcaaa gatgatccac acttttttga
    11461 aacaaacttc tggtttatgt gggaaacaac atttgctttc agaacacgta gttctgctca
    11521 agaattgcgt cgctatatgc atcaaatgat ttatgaattc actcaaatcg aacatctagt
    11581 gggcgtcaat cgaacacgtt acaatcaata cgaaagtatt atgcttcctt tgatcgagta
    11641 cttgaaagaa caaggatgca aaatcatttt gaaccgccgt gtcactgact gggaattcaa
    11701 agaaacaccg atgcaagatg aaatcactgt gactggtttg aaaattacca atacactgac
    11761 tcaagaagaa gaatacgttg tggtcgatga agatacagca gttattttca ctaatgggtc
    11821 cattacagat tcagctactt taggagatta cgaaacacca gctgtagaaa atatggatta
    11881 tggtgcagct tctagtctct ggaaaaaagc cagtgaacgt ttctacaact tgggaaatcc
    11941 tgacaaattc tttgctgatc gagatgcaag cgaatgggtc agctttaccc tgacgacgaa
    12001 aaaccatttg ttgttgaatg aaatcacccg tatcacgact caagaaccag gaaatgcctt
    12061 gaattcattt atttcaacca caccgatcac gccgttaggc caaaaagatg tcaatatgtc
    12121 tattgtcgtg catcatcaac cgcattttac gtctcagaaa ccaaatgaaa cagttatttg
    12181 gggttatttc ctttatccaa gacgacgtgg cgaatttgtg gataaacagt atattaaaat
    12241 gaatggaaaa gaaatgctag aagaactgat tggacaactt tcaaaagtag atcctggacc
    12301 agtgaatatt cgtgaaaaag aaacagaaat tttcgacagc gtaataaata atatccctgt
    12361 ctatatgcct tatgcttccg cgttgttcaa taatcgtgcc aaaagcgatc gaccaaaagt
    12421 cattcctaaa cattcgacca atctggcctt tacaggagaa tttgtcgagc agccttatca
    12481 gatgatcttt actgaacaaa gtgctgtacg ttctggagaa atcgctgctt tccattttgc
    12541 gggtattcct atgtcccgtc ttgtcaaaac accgcgttac gacaaagata ttcctactct
    12601 agctcgtgcc gcaaaaaaaa tgtttgaata atcaagaggt tgtgaaaaag ctgccctgca
    12661 tcaagtaata agaacaacca ggctaaaaca gcttcttatg tttttgattt ggttggactt
    12721 attaccgcag atgcaagctt ttgaacaccg tttaccaaga ggttatgaaa aagctgccct
    12781 gcatcaagta ataagagcag ccaagctaaa acagcttctt atgtttttga cttggttaga
    12841 cttattaccg cagatgcaag cttttgaaca ccgtttacca agaggttatg aaaaaggcgt
    12901 ttagtttcga gtatgaagaa aaattttgtg aaaatggttc ctcacgtttt tgcataaatt
    12961 tgacttaata ccgagaaact gatcccttct gtcataacct ctttttattt atgtctgttt
    13021 ctttttgaaa acaactattt tttcaacgtt tactctcttg ccaatccaac atcatctaac
    13081 ggatacaact atttcaatga ttaccattac actaaaaaat cggaaacaca cctctccgaa
    13141 cacaaataca taagactata gaatgtttca tttaagaaaa aaagcgtttc attatcaaaa
    13201 aggtaagatc tcctttaaaa tgaaattatc tgtagtacta ataatgcaga caattttatg
    13261 aatctgaaag gagcatctcc aatgaaagca gtcacttggc aaggaaaaca gaaaatggaa
    13321 atcagaaacg tagatgatcc aaaaatatta gaaccaacag atgcaatcat ccgtatcaca
    13381 gcaacagcca tttgcggctc cgatctgcat ctttaccatc atggtgaagc agttttggaa
    13441 aaagggtatg ttgtaggaca cgaaccaatg ggaatcgttg aagaagtggg atctcaagtt
    13501 caaacattga aaaaagggca acgtgtggtt atccctttta atattagttg tggtcattgt
    13561 catttctgcc tgaatcacat ggaaagccaa tgtgatgaat caaatccaga tcagttatat
    13621 ggcgggcttt tcggatttgg caagttgaac ggtaatcatt ggggtggtca agcggaatat
    13681 ctaagagttc cttatgcaga ctctacttca tttgttgtac cagataatga tcttcctgat
    13741 gaaaaagttt tatttctatc agatattttg cccacagctt attggagcgt tgaaaacgca
    13801 ggagtaaaaa aaggcgatac agttgtgatt ctaggttctg gtccagtcgg tctattcgct
    13861 caaaaattcg ctgttatggc tggagcagag cgcgtaatcg cagtagatcc agtacagcac
    13921 cgtctagata aagcggctaa ttacaatggg gttgaaactt atttcttaga agacacggca
    13981 caagctggaa cagaattgta tgaactggct aaaggtggcg cagatgtcat tatcgattgt
    14041 gtaggaatgg acggattaga gcctgtcaaa gaaaaagcga aaaatttagt aagcttacaa
    14101 agcggcacaa tctctccatt acagatggca tcgcaagctg tcaaaaaatt tggaacagtc
    14161 caagtaactg gtgtttatat gactccagct tcttcttacc cgctgcaaga attttttatg
    14221 cgggatatcg ctgtcaagca tggacaggca ccaattatcc atctaatgcc aaaaatttac
    14281 gcaatgattg cagaaggact attcgatcct acacaaatca ttactcattc gctgccacta
    14341 tcagaagcag cacaagcata tgagatcttt gacaaaaaag aagataaaaa tataaaagtt
    14401 gttttgaaac cttgaattca gtaaaaaata caggtgattt tctttatgcc caaaatcaaa
    14461 cgaaataccc atgagatcga aataggaaaa gaagaagata tcgaaatacg aggacgtcgc
    14521 ttccgcttct atttccaaaa tcgttacaca ttgatctcac tggctgtcga tttattaacc
    14581 gggattttct atatttttgg aagccttgct tccttaacta aaatccccga tcgatatggc
    14641 acctattttt atttggctgg tgctattttc ttgacgattc gtcctattct cagaatcgta
    14701 aggaacattt ttatttacga cgaaaaaaaa gcaatgaaga gaacaagcaa aaaaaaagag
    14761 gcatgagaat ttttcaaatc tcatgcctct tttttcaccc tatcgtatca ctttgataca
    14821 gacgagcggt cgtcccactt tcttccttga ccattgtcaa aaatgtccac tcgtatcgtt
    14881 cataaaacgt ggtatgatct gtaattaagt aaagtttttc gtacccaagt tgatgcattt
    14941 cttttctgat ttccgctaat atccgcttgg ctatcccctg cttacgcttt tccggttcaa
    15001 caaacagggc acaaagattt ggtgtcagat cagggcggtt atggaagtcg ttttcaatga
    15061 cgcccgctcc tccgacgatg gtttcttttt catctaagac cacataccat tgaggaatac
    15121 tttccttatt agcgattcca gtacgaatac tttcctcata cacaacagca ggaactcccc
    15181 attttgatga aaaccaattc gcgctttgtt ttactaattc tgggtgttct cttaatttga
    15241 tccagttata tgtaaccaat gtttaaacct ccgactaaaa taaaacgttt acaaaaatta
    15301 tacaagtctt tatgaaaatt agcaatgaca acaatagtga tgtaaaaaaa aaaacggaaa
    15361 acaatcactt gttctccgtt ttttgattaa tcaagcatct aaagcttctt ttcttctttc
    15421 ttggatcgta gctaccttga cgaacggtag atagatcaaa atagaaagaa ccaaattgac
    15481 agcggctagt acaccacctg caatactttt tgttgccaat acaccgccaa taattggtgg
    15541 agttacccat ggaggcataa cggtagctgc tggcactaaa cctgtagaag tcgcaaagta
    15601 agcaacacta actaagacca ttggtgtcaa aataaatgga atgaacatga tcgggttcaa
    15661 cacgataggt aacccaaaca tcgttggttc attaatattg aagacacctg gcgcaatcga
    15721 caagtttgtt acaaccatat atggtttgtt tttacgtcct actaaataaa tagctaacag
    15781 taaacctaaa gttgcacctg ttcctcctaa gttgacaaag ctgtcaaaga aaggtttgtt
    15841 cacgataaac ggtgcgctat gtccagctgc gattgcatta acgtttgctt caatggctgg
    15901 cgcattgatt gtttgcatca aaggatcgac catattcgct ccgtgtaaac caaagaacca
    15961 taagaatggt gtgataaatg caagcagtaa ggcagatgga taagagtttg caagtcccat
    16021 aaatggttct tggaccactg tatagaaaga acctacgata tcatcaacac cgaatgcagc
    16081 aaaaattgca gcaactaaag caaacgcaga gatagtgatc attgctggta gtaatgaagc
    16141 aaatgctttt gcaactgccg gtggcacacc atcaggcatt ttgatgatca atttttcatt
    16201 tccgcttaaa cgtacaaaga tttctgttga aataatccca acaataatag caataaacaa
    16261 accgtttgag ctcataccta atgctccgcc taaagcgaag aaagagccta aagaaatcac
    16321 acctgcggaa acaccgtctt ttcggtagcc gttagctaaa tgataagcaa gcaagaaagc
    16381 aatcaagaca gaaagaatgg caaatgtacc gttccaagca gcagccccga atcctttcca
    16441 tgattcacca ccaaaaattg agttcatcaa ttcttggaac ccgggaatcg gtaagttatt
    16501 gatcattact gctaatgctc ctaagatcat taacggcata ctcaccataa atgagtcccg
    16561 aatcgcaact aaatgccgtt gtgcaccaat ttttgatgct acaggtataa aatgtttctc
    16621 cataaatgca acaaatttat ccataaatct tccctctttt ctttactgta gattacgcgt
    16681 tcaatcgacg atacagatca atgatctctt ttgctaaatc tgtaaaagct atagatgtca
    16741 tcagatgatc ttgactgtgg accgtcaaaa gcgtgacttc aacgtgattt ccttgtgctt
    16801 cttgtgtcag catctctgtt tgagagtgat gtgcttggac taaagattcc tctgcatctt
    16861 tgattttttc atctgctaaa gtgaaatcac cttttttcgc agcagcaatc gcttccattg
    16921 catcgctttt tgcatttccg ccaaacatga tcagacccat gatggcttct agattttttt
    16981 gatcttccat ttattgtatc ctccgataat ttttattatt tgtttattag tttttctgct
    17041 tggtcgagta ctttttcacc attcatcatg ccatagtcag ccatattgat tacatctaaa
    17101 ggaatgcctt taggtgctag cttttcagca aattgatttt gcataaagcg tacttgcggt
    17161 cctaaaagta aaacgtctac atttttagat tctagttgat tatccgcatc tgaagcagat
    17221 acagcaaaga tgtctgcttc cattcctttt gcttctgctg ccttttgcat ttttgtgact
    17281 aggagacttg tactcattcc agctgaacat acaagcatga ttgttttctt ttccatttta
    17341 aacacgttcc tttctatact tacacttgta tataagcaag tagcgtgcca actttaaaag
    17401 cgctttaaaa agttgatatc atcacattta aggtctatac caagttgcat acacactaaa
    17461 aaagaaagcg cacactaaac acacaaatta atttttatta ccttttttct tttaacgtgc
    17521 acaaaaaaag ttgtgacaca aaacttgtca caactttttt caaataaacg gtattcaaaa
    17581 gcttgcatct gcggtaataa gtccaaccaa gttaaaaaca taagatgttg tttttacttt
    17641 gctattctta ttacttgatg caggacagct ttttcacaac ctctcaataa acggtgttca
    17701 atcagctgac cctgggtatt agctcaaaac gctggattca caacctcttt tatttcaaat
    17761 aaccagtaaa tacaatgaac atctacaaaa aacttctatt tatttataga tttcgtcagg
    17821 caaatccaat tctctcttat caatcaaagt ctgataccac gaagcagatt ttttcaatgt
    17881 tctgcttcgt tcatcgttca attcgattcg aactaatcca tatcgattct taaatgcatt
    17941 cattggtgac acacagtcag tgaatgccca taacatatag ccttcgcaat ttgcgccttc
    18001 ttctgttgct ttgatcaagt aatgcaaatg ctgtccgata aattcgatac ggtaatcatc
    18061 ttgcacgatt cctttctcat ccatatactg ttcttcatat tctcttccca taccgttttc
    18121 tgttatcagc caagggatat tatgataatt ttcttttaga tacatggcta tatcatacat
    18181 gattttcgga tagatttccc atcccctgga attattcatt ttcttcccag gtaaatcaaa
    18241 gacttcataa tatcgttcag gatggaaagg tgtctcttca ttccattgat aacgaggggc
    18301 gcgaacgcgt ttaggataat attgattgat tccaaggaaa tctactgtat gatgctgaat
    18361 cgtttctaaa tcctctgttg caggatcgaa ataaatcgat tgtttttgac acaactccag
    18421 gaactcttct gtgtagtatc cttttaccat cggatcaaaa aatactcgat tataaaacaa
    18481 atcatacata taagcagctt tttggtcttc tggagaattg gatcgagcat agaccatttc
    18541 aggatttaaa atacagccaa tccttccacc ataatttccg ctgcggtaaa tctctactgc
    18601 tttagccgtt gctaaaactt tatgataatt ccacatcatc cacttttttg tgttttgttc
    18661 atgcggccag cgaacagcat ccaaatagca acgcgtttgg ggaacgattg gttcgttgaa
    18721 tgtaaaccag ttttttaccc tatcaccgta acgatcaaag gcaatttgag catacttagc
    18781 ataaaaatca actacttttc ttgaagacca gccatcatat ttttccaaaa gaaaagctgg
    18841 gacttcataa tgttccaaac aaatcatcgg ttctacgtct gcttcgatca aagagtcgat
    18901 catttcactt atatgctgag catattcttc atctactata cagttctcat aatcagtaaa
    18961 aaaacgagcc caattgatag aagtccgata atgtgtcaga tggatggatt tcatcagatc
    19021 cacatcctgc tggtattgtt ccataaaatt agttgctacg gctgggccat acccattatg
    19081 ccaaacaaaa tgttcatttt tataccagct atctataaac gaatcctgtc cttctttttt
    19141 tcctttccaa ccttccgttt gccaagcaga agatgcagca ccaagaataa aattttttgg
    19201 aatagtaatt ttcatgattt cctcctgttt tttagatccc atcattttcc acacgatttg
    19261 ctacttttac aaatggcaga tagatcaaaa tagaaacaat aatacaaaca agttgcgtaa
    19321 taactgcacc gatatttcct gctgttgcca gataagcatt gacgatcggc ggcattggcc
    19381 aagggaccat tacaactgct ttcgccgcaa atcctaaagc ggttgcaaaa taaccaatcg
    19441 ttccagtgat aagaggcgtt aagataaacg gaatagctaa aattggattc agcatgatcg
    19501 gcataccaaa aataactggt tcattgatgt tgaagatccc aggagcaagg gataacttgg
    19561 tgatttgttt catatcttcc cgttttccaa ctaacaatac tgcaatcagt aaaccgatcg
    19621 tgactccaga cccgcccata ctcatataca tatcccaaaa tggcatagta ataatgttcg
    19681 gtacttcttt tccagcttca aaagcttccg tatttacagc aattgccgct aaaagcaacg
    19741 gttcccgtat cggcttcacc atttgatttc catggatacc aatcacccaa aagacttgcg
    19801 caataaacat caatagcaaa atacccggta acccttgtac gacaccttct aatgggcgtt
    19861 gtacgacatt gtaaatgata tcataaaggt acattcctgt aagttctttg atgataaatc
    19921 ccgcagccgc gatacccgat acagtcagaa tcgtcgggaa taaagcagaa aaactagcag
    19981 aaacattcgt tggcacggta tcaggcattc tcagctgtag tttcttctgt ttcctcaacc
    20041 agcaataaag ttcaatagaa aggatggaga ccaacattcc caaaaataac cctttcgtat
    20101 ctgtatattg tttagccaat acgttttcta ctataacagt ctgattttca ttcactaatt
    20161 cataaacagt tggattaaca gataaataag acatcactgc gatgatacca gggaatacac
    20221 catccacttt attcagcttg gctaattcga tccctatcag aaaaacagca tagatggtca
    20281 agaaacttag tgtgacatag ctgatggcag atgcgatagg ctttaattct tctaaaaaac
    20341 gcaagaaact tatctgtgct aagccatttt ccgagtcaaa gaccattgct gaaaacaatg
    20401 tgccaaaagc acccgtaata attaccggaa tcaatgcagc aaatgcgttt tttatcacca
    20461 tgatatacct taaattattg attctcgttg ccacgttccc taaaacattg gctaatttat
    20521 ccataaaact cattccagat cccctcattc ctgcttcttc tccttgacgt catctctttt
    20581 tgtctattag tcagcgctta catttcgatg aacagaaact atttactcct cttttttacc
    20641 aaatataaaa caaaaattca tctgatgtat ttatcataaa atacatcaga tgaactgtca
    20701 attagtttct ttttctccta ttattttctg taattctctc cgatttattg ccatatggac
    20761 agtcattgca tcaaacgcag caagtgcatt ccgcctttcg atggcctgaa cgatctctgt
    20821 atgaatatcg atcgtctcga ttttcagatg ctggatatca taatttttat taaacaaagc
    20881 aattgattca ttaatgattg ggataatatg cagcaaggct acgtttccgc tagcttctgc
    20941 aatcatcgta tgaaaatcga tgtctaattg aacatgttct tgtgtgcctt ctcgaaaaga
    21001 agtttcaatc ttttgcgtta attttttcat ttggacgatt tgattcttcg ttgcatattc
    21061 cgctgccaaa cctgccatct taggctccaa taaatatctc agttcaaata agtctcgtat
    21121 catccgatcc tgatcttcaa tcaaagaaaa accgagtggg tcattggcaa tccctcgctt
    21181 atcactgaca aatgtccccg ctccttgccg aacttcaagg atattcctgg aagctagagc
    21241 ccgcacagct tctcgcaccg tgcttcgccc cacctctaaa taatcggaca attcatattc
    21301 attcggcagt ttatctccta cttgcaactg catttccttt aaatatctaa ggatcttgtc
    21361 agtagttact tctactaggg ttttattttc ttccaaacca catacctcct tttcatctga
    21421 tgtatttttt cgtaattatt ataacacgtt tgaatcatct gatgattttt tgtatacaaa
    21481 attgattaat ccgttcatag acatacaaac gaagaagata tttaccataa aaaagactag
    21541 gataaaattc actcctagcc ttcgatcatt tttattttga acgacaaaaa atatgatgtt
    21601 caataacaga cgatcttcat tcgattcttg atgtcatctt ttgttttttt taatatatgg
    21661 ataaaaagtt tgattacatc gtttctattc tagaatttgg tcgattctca attcttcttc
    21721 tggtgagaaa tctaaattat ccatcattcg aacactttct tgtaactgac ttaaccgact
    21781 tgctccgacc agtacacttg taacagattt ttgtcgcaaa ttccatgcaa gggccatttg
    21841 cgctaatgat tgtcctcgtg atacggcgat tgtttgcagt gctttgattt tttccagagt
    21901 tgatccaact tgttcttctg aaaggaatgg tatttcctta cgatgtgctc tagaatcttc
    21961 aggaatacca tgtagataac gatttgtcag caacccttga gcaagcggac tgaacgtgat
    22021 tgcccctagc ccttcttctt ctaatactgg agatagatcg tcttctagta gtgcacgaga
    22081 aaacatattg tagcgcatct gatgaataat gaacggtgct tcctttcttt ttaaaatttc
    22141 agtcattttt tttgtatctt ctccattata gttggatata ccaatatata atgcttttcc
    22201 ttgtcttaca agttgcatca aagcttctgc tgtttcttcc aaaggtgtat cagggtctgg
    22261 gcgatgatga tagaagatgt caacataatc tagccccatt ctttggagac tttggtcaca
    22321 acttgaaatg atggatttac gagagcccca ttccccatat ggcccttccc acatatgata
    22381 acctgctttg ctagaaataa tcagttcatc acggtaggct tgaaaatctt ctctaaaaat
    22441 acgcccaaag tttttctctg cagctccagc agggcctcca taattattcg caaggtcgaa
    22501 atgggtaatt cccatgtcga atgcgcctct taaaatctct ctttgattat ggataggatc
    22561 ataatcacca aaattttgcc ataatccgag agataaaatc ggtaatttca aacctgaatg
    22621 accggattta cgatattcca ttttttcata acgtgcacta tctgcaatat acaatttttc
    22681 tcctcctcat caaatctttt taaaacgctt tcttttttct atttttagtt tactacattt
    22741 taaagaaaag gagttaatca aaatgatttt ttcgtatatt tttttgccat ttgtttttta
    22801 ctcgttgata gatcagaaat tgattacgtg cttgctggat ttttttataa cgtttcggtt
    22861 gttttttgta aaattgctga tgatagtttt ctgctggcca aaacgtaccg gctggttcga
    22921 tttttgtgac gattggttgg tggaaagttc ctgaactgtc tagtttctgt tttgattgtt
    22981 ccgctaattc tttttgtcgt tcgacttgat aaaaaatcac tggacgatat tgcttccctc
    23041 tatcttgaaa ttgtccaaat gtatctgtgg gatcagtaat ttgccaatag attgtcagca
    23101 actcgctata acttatttct cttgtgtcat aaatgatctc cacagcttcc acatgacctg
    23161 tgtaaccacc acttacttga tcataatttg gtttttcaac atgtccgccc gtgtatcctg
    23221 acaaaacaga taggatccct tttttcgatt caaacggctc gaccatacac cagaaacatc
    23281 cccctgcaaa tactgcacgt tcttgatagt cagcatcttg catggcatgc ttggaaaagt
    23341 catatttttg ctccttatca aatccttccg taatcaataa ataaaagtcc attacatcag
    23401 gcgtcagatt cattcggata gctaatggac gtagtgttgc ttctagtttt gataactgtt
    23461 ctttaacgga tatattttct cttatgtcat tctttgtctg aatcaatact tttcgttccc
    23521 aatctcgtgt attcggattc aaaatcagat tataaagtgt ttgaatgaat atttgttcct
    23581 catccataga ttctcctcct ttccgaagaa gacaagctag tgactttagc tgtaatttat
    23641 cataaagtga ggaaataagc gattacttca tccccctaca gatttttcgt ataaaaaaga
    23701 gagaatcctt atcgacagat tctccttttt aatcaattta ttttataaat gaaaagttaa
    23761 tttacctttt atggaaaact attttaaaaa ataaacataa atatgcagtt aatgtaacaa
    23821 gataagaaat aatagtcgtt actgtataac ttgtgcttac tttaatatca gcaactcctt
    23881 tgactccgct tatttgtacc aatccattag cattcacctg ctcctttaca ggttgatgat
    23941 ttatttctac attcgttcct aaataagcat atacaggaag tgtgattact tggctcttct
    24001 cattagttac tctatatatg atagaactac cagttgtttt ataaggaagg tttacccatt
    24061 gactgccaat ctttgcttcg tgttttatta tatgctcctt attctccaat gaagcgatag
    24121 gagaataatc atataaaaaa taatccattc ctttagtggt atacgcctct actgtttctt
    24181 tgtttacaac aatatgtccc ggctgagaaa ttattttttg attgaaattt tttttactag
    24241 aaacagttaa agtgattaat aacaaaacag tcataaataa ataaaatagt tctcttgtct
    24301 tattgtatct tctatttttg aaaaatatca tcgttaatat cagagaagag aatattattt
    24361 gcaagcttaa gatccgccaa ggaaattgta acaatttggc tggcgtattt tgcagaagat
    24421 accatggcac caaactagtt gtagctagcc aagtcaaaca cgtaccataa taaatctttt
    24481 tttctatgtt tgttaatttt ttaaataaaa tcaggggaat acataaagat aacagaccaa
    24541 ctagtcccat tgagtaagta gttaagtcgt tgttcatagc ttcagtcaga ctatcgaaca
    24601 cattagatgc atgagcatat aaatttgtca cgctaggttt gttgattttt tggtagagca
    24661 tttgttcaaa catcggatac caaaaagcac tcgtcagaac caatgtcatt cctgccgcac
    24721 taaataattt tttaaatata gcaataaaat ctgcattctt gaaaccttta gaaaccaaac
    24781 gaataaaaat aaaaatgata attaatgctg tactcattaa tgttgatagt acatggctgt
    24841 acactagcaa actcatactc aatgctagct ttacagacgg atacttttct tcttttccag
    24901 agatgatttg ataagcataa aataatacag ggataacaag tgttattgcg atagcttcgg
    24961 caattgcgga acgatagtag atgtctactg tccgataagc agagaaaata tagagacaac
    25021 taaataaaaa tgccgctttt ttttgtttta aaaaccgctc gccataatga taagctacga
    25081 gtgttgtaca caagttcaat aaccaaacgt aaataatata gcttacaatc aaattttttg
    25141 tcatccaata taacattaca gctggaaaaa aagtcagaaa gggataaaaa taatttacac
    25201 catatccagt ataattgaat gtctcataat taatcggact ggtaaaaata gtcgataacc
    25261 ccttgattcg agataagtga aaagaaagat ctccagtggt ataaatactc tgtgtatttt
    25321 tgaaaaagat gaaagaatat atactactaa ctataattaa tccactcaat attactactt
    25381 ttttatttat tttcattctt cttgtttatc tcctttttag tcacatatcg agaatctttc
    25441 aacttattag gtgcaaatcg tttaaaactt gaatacacca ctaaacaata agtcagaata
    25501 ctgatccata aagccatgag agcagttgga gtatattttg ttgtaatttc tatcttattt
    25561 tctccagcat ttacatccac attcactaag ccatgttttt tataagagtc atttacgact
    25621 ttaccgttta cttttacctg tgtacctaaa taagcatata ctggtactgt cactttttgc
    25681 tttttgttgc ttgccactgt gtaagtaatg ttattatctg cagctttata cttccctttt
    25741 tcccacgatt ctcctacttt tacttcatgt ttttctaagt gaggcctttc ttttatcgct
    25801 tctgttgggg cgtaatcgta taatcctccc atatctgatg ttgtataacg tgggagtgtt
    25861 tcttcattga taacaatatg accgtgtttt gattggataa cttttgcgta attttctttt
    25921 gctgctatag acgtgacgag tagaaacacc acagtagcgc caatgattaa ccatgaatat
    25981 tttttattca tagtcttttt cataaaaaca agcgttatga tcattgaaga aaaaaagatt
    26041 tggataccta agatacgcca aggaaactgg agtaagctta tcggtgtttt ttgaaacaaa
    26101 aaccatggaa ataaattagt tacgcatacc catgtagaaa ctacgccaac atagatgatt
    26161 ttttcttttt tctccatttc tttcagtatg aataaaggaa aaatcaacgc aaccaatcct
    26221 aataacccca tagtgtatgt tgtaatatcg ttatttaacg cttgaatgat actatctgaa
    26281 atagaaagtg cttctagctg caaatctgtt ttgaagggac tgtgtatttc ttgataattc
    26341 atctgctgca acataggata ccaaaaatag ctagttaatg cacaagtcaa aaaaacagcc
    26401 tttactaaat tcacgaccac aaattttata tcgtttttta tttgcttgct taaaaacaaa
    26461 cgaactataa tcatacaagc aatcaatgca ctacacaata gtgtagttaa gacatgagta
    26521 tacacaagta gacttatact gacagataaa gcgatgactt ttttttctct attgaatatc
    26581 aatccataag cataatataa aacagctggg ataatcgtaa gagcgattgc ttctgcaatt
    26641 gcggatcgat aatagatatc aactgttcga taagttgcaa aagtatataa acaactaaat
    26701 aaaaaagcag catctatctt tttaaaaaac ttttctccat aataaaaact aatcagaatc
    26761 gtacaaatat ttaataacca aatatataga acataactta atattaagtt atttgaaatt
    26821 ccataaaaaa cgactgcagg aattattgta agaaaaggat aaaaatagtt cagtccatct
    26881 ccataattgt taaatgttgt atagttgatt ggcccttcaa aaatagaaga taaccctttg
    26941 attcgtgaaa gatgaaaaga taaatcacct gttgtataaa tttcttgagc atttctcata
    27001 aaatttactg aatataaagt actaagtaag ataagaacta ctaaaagaaa tgctttttta
    27061 cttattttca tagatttgtt gttctccttt tttaattcta ttttcagtat actagaattg
    27121 tcttttttta ataagttttg cgttaaattt ttcatagcac tagtatgata tactagaaaa
    27181 gaatcaattt ttattacttt taaataggag aaaaaaatga aaaaaaacaa aaaccaaata
    27241 atagatatca tttttatgtt atttctaagt tttgcttacg tcatccctct attcatgtct
    27301 aagggaatct atcatagtgt caatcaggat acttactttc atttatctcg aatcatagga
    27361 ctagataatg tatggagttc tccagtaaac ttcaataact tcgatcatca tggaacaatg
    27421 atgaatattt tttatccatg gcttactctt tatccagctt ttttatttta taaaatgatg
    27481 ggaaatcttg ttttaagtta taatatctac tattttttta tcactttttt aacaatggtc
    27541 gtttcttatt tttctatgaa acaaataaaa aacaatcgtt atatttcgct gttattttcg
    27601 attatttata cattttccgc ctatcgtgcc attgacatat tccatcgtgc ttcattggga
    27661 gaagctgtcg ctttaacatt tttgcctttg atactaatgg ggtgttacga aatttatatt
    27721 agagattacc aaaaatggta ctggttgtct attggcatga cgctagtagt gtatactcat
    27781 ttactttctg tcgctatggt ttctgtattt attggaggaa cgttgtttct ttctttttat
    27841 ttttgggacc aaaaaatcgc tagactctta agtcttttaa aagctaccgt cctcaccttt
    27901 tttttaagtg cgggattctt aattcctttt attcaacaat ctagagcaca agaattgaaa
    27961 gtcccactgg gaaaagaatt aagtggtatg gctcctagtg atatgctgac acatatttta
    28021 aataataact ataacaacta tactattgga ttattcttat ttctcggatt gattggtgct
    28081 tttattttta taaaaaaatt aactgctgat gatttattta ttttctttct tggtgtattt
    28141 gttctttttt gttcaaccaa tttatttcct tggcaacttt ttaaccatac accagttaag
    28201 agtctacaat ttgtctggcg gttaaatggt ttttcttctt tatttatagc ctatacgatg
    28261 agtatagtga tctattatat tttttctact aaaaataatt catggaaaat aatggtcttt
    28321 acgtttcttg cactaatatt gcatctctca ggagtaagca attctatcca tgctaacaaa
    28381 gattcattaa cacttatagc acctgaagac gctgttgcta tagctgaaaa ttacaatcat
    28441 actgattatg caaacaaaga gtcaatctat catcctgata tgattaataa tgatcaatat
    28501 ttactaggta accaggaaat aaatccaaca actcatttta tgagtaacaa acttacaatt
    28561 gaattagata attcgaataa taaaaatact gtcttgacga cacctattta tcgttataaa
    28621 gggcaagtgg cttctattaa tggcaaacta gtacaaacaa aattatctaa gtttggcaca
    28681 actgaattaa ctattcctcc aggtataaat aaagtcgtta ttacttatca gtacacaaaa
    28741 ctagcaattg cttcaagata tttatctatc gttactttga ttttattttt actttatcga
    28801 tttacttttt ctaaacaaaa acaaccgaga agagaagtac aacattctca ctagattttt
    28861 atttaagaaa gactttttag ctgtacacat aaacaggcta aaaagtcttt ttttatattt
    28921 ctttaatttg cttcatacat tatttaacat cgatatttat actgtgaaac atgcgtttca
    28981 tccattatca aagtattttt atcgataata aacttcatcc aaaaacagac cttgtgcagg
    29041 gacggtttct cctgcatgtt gccgcacttt gctttcaaat atttcatcga ttgtttctat
    29101 cggcatggca cctgtgccga tttctagtaa tgtccccatg ataatccgca ccattttata
    29161 taagaatccg tctccgacaa aagtaaaatg aagcatttct ccctttcgtt cgatagataa
    29221 ttcatcaatc gtacgcactg tggatttttt tgattttttc aatgcagaaa aaccaatgaa
    29281 atcatgtgta cccactaatt tttcgcaagc tgcattcagc ttgtccatat ccaactcttg
    29341 agggaaataa aagctgtggt ttcgctcaaa tgctgaagga atcacgttgt tccaaacata
    29401 atagctgtat tttttgccca ccgcattata tcttgaatgg aagcgctcag gcatttcttc
    29461 gattcttttg atgacaatat cccgcggaag gtaacgattc ataaagtcga tcatttctgc
    29521 cagtccaatt tctgtgtttg ttttaaaatt tgctacttgt cctcgcgcat gggtgccagc
    29581 atctgttctt cctgatccaa taatttctat ctcttcattt gtcatctgat gcaatacttt
    29641 ttcgattttt ccttgaatgg ttttatcgtc atctccaagt ctttgccatc ctgaatatct
    29701 ttttccgtca tattcgattg tcaacttgat gtttctcata ttttagtggc tcctctgtct
    29761 tccatttggt cttctctcta cctttttaag attgtagcac aaaatatagc tccttgcttc
    29821 tctaagacag aagctataca agaaaactgt ggaaatatat atttcagaaa aacaaaaaac
    29881 agccaccgga tgaagtatcc gctgactgtt caatttgacg gctcaagttt tactgtttga
    29941 gatgcaagat actcaaccag gcaatgggca cataattaaa gaaaaaactg attctttggc
    30001 aaaaacctat tttattcagt aatggccaag aatttataga aggaattctt gccagtccat
    30061 aaatcgccgc aaaaagcaaa ctgatcacag acagtccaag gtataagtgg cttacgtcca
    30121 tttgcccatt ttttcgatag atcaagaaaa gaagaactgg aaacaataaa aaaccactgt
    30181 aacctaaacc tgatccgata ttatggaccc atgtcgagac attccacgaa gattcatggg
    30241 tattgatact gaacaaacct gtaaagatac aatcacctat accatagaac gcgatggctg
    30301 ctgtaactag ggtagctaac acacgagatg tactaacaaa tgcagcatac aatgcaggca
    30361 atgacaggat gaaaaagatc cctgaaacca cagaccaaat aagaaacgct tttcttacag
    30421 gactggaaac ctctccaaat acactgatca cgctcttcat ttgatctaat tcaggataat
    30481 acaatcctaa tacgtacgga gtcaaaaaat cactcagcac gcctaataat aaaaagaaaa
    30541 aaccaaattt acgtaaaaaa tccatgatac gcctccaata acaattacct atgcttttaa
    30601 ttgttattat aaacgacttt atcttgattt aacagaaacc tctatttaca cgaacatcta
    30661 tataactcat taaaaactcg aatcatttta aaaatactaa atatctaacg ttcaacgttc
    30721 acttaatcca tctaaacaat ctttcaattt gattttttcc ccacttcttt tacgcgcgcc
    30781 tagctctcct attgcagtaa acaacagatc acttgacgaa tttaaggcag tttccattga
    30841 atcctggata acaccgataa taaatccaat accgacgatt tgcatcgcga catcattaga
    30901 gataccaaac aaactacatg ctaatggaat caataacagt gaaccgcccg caacacctga
    30961 agctccacaa gcagctaaag cagacaaaat acataaaagg actttcaaaa caaaaggtgc
    31021 ttcaatccct aaagaatgta cagcagtcaa cgtcatcaag gaaatggtaa tcgcggcacc
    31081 gcccatattg atcgtagcac ctaacgggat cgatatggaa taagactctt ttgtcaattt
    31141 caatctttca gccaacatca tgtttatcgg gatatttgcg gcagaacttc gggtaaagaa
    31201 agcgggaagt gcgctttctt tcaaacaaaa gaaaatcaat ggatagggat tttctttaat
    31261 aaacaaaaac gtgaggaatg ggtacacaac taatgcgaca aacagcatcg taccgatcaa
    31321 aacaagtaaa agctgcagat actctgccaa tccagcgatt ccagtcgtag caattgattg
    31381 ataaaccaat cctaaaatcc ctatcggagc aaatgcaata atcacttgta cgacttgtga
    31441 caacgctata gatatctgat ccaccaactc ttttgtcgat tctgaacgtg ctcgaaaagc
    31501 tagtcccaac aatacagccc agaataagac gccaaggtaa ttcgcatcaa taagagattg
    31561 aacaggattt tgtgtgacat tcgtcaacat agtagataaa acactttcca aactttgcgg
    31621 tgctttttca gatactgttt cttgtaaagt aataggaaca gtaaaaattg aacttacaat
    31681 aactgctaca agtgcagaaa gcaatgttcc cactaaatat aagatcaaaa taggcttcac
    31741 gaatgtctta ttcccaattt tatgcttggc aattgacgcc atcgtcaaga aaaaaaccag
    31801 aataggtgcg attgccttca agcaactgac aaacaacgtt cccaatattg aaataaatgt
    31861 ccatgtgggg aaaaagatac caaacaatat tccgactaaa ataccaacaa caatacgttg
    31921 aactaacgac atatccaaaa acttctctaa caaatgacca ccctttcaca attttaacaa
    31981 tcattgtatc attttatgca aagaaactaa aggtataatt ttctaaaaat tctaacaata
    32041 caaacaacca tttcttgcta attttgtact ttttctgtct acacgttgtt ttttgagata
    32101 ttctaagtta ggatgttatt aatgggcaac ttatcaggaa acgttttctt atgtttttgt
    32161 ccaatttttt tgtgaggtgt ttattcttga aaaaaataaa gaaggagagt tatggcttcc
    32221 tgacaatctt tgtcgcttgt ataatgatgg ttttacagcg tatattgatt tcagcagtca
    32281 ctattcctac atatgcaaca aaccctggtc gattctacat ctatacattt ttacaaactt
    32341 ccgttgttat tggtgcaaat ttgatcccac tttacatggg ttaccaatat caaaaaatcg
    32401 cccgtttaaa agttttacat tatttaagtc gttttgcctt tatattccta atagccacac
    32461 tagtttgcaa tatctttttt tacgtacaag ctggcagctt gaatattcgt gattattggc
    32521 ttatcctaac acctatcagt cagaattact ttacttatgc tgtttcttgt actttgcttt
    32581 tttgtagtat tccttataca gttggatttt taaataaatt atcgaaaaca acaattaaat
    32641 atctactatt atttttaaca attggattag ttggctgctc tactctattt aataaagacc
    32701 cgtttgcatt acagaatgga cagagtattt tatggatttt ttatttattt ttaatgggtt
    32761 atggtttgaa agaatggaac tggaaagaaa aggtccgcta taagcttcct caagtattta
    32821 tcagcttgat tgttttattc ggtttgatta ttttgatgac acaaatttca ctcatcatca
    32881 gaggaaatac agatacagcg ctgaggtttt ctaaaccata ttctctcttc gcaatgtatt
    32941 atactttctc ttcgttttta tttttagaaa tgctatctga taaattaggt ataaaaggaa
    33001 gaggaaattt tcttgctgta tttttgattg tcactcaagt tatatgtaat ttccctttag
    33061 tttcttatcg cgtatctaca tttatgaaac gtgaatttcc aaactcaggg aaggcatggc
    33121 tgataaatat cgggcagttt tttatttgat atttattagc agtgtccctc ctagttatct
    33181 ttttatttta tatacaaaaa atccgtttca ttcatcgttt catcgaatac ttcgcttttg
    33241 attcgattga acaattaact cagcgttgga aaaaaagaat tcattggctt tttgttcata
    33301 aaagttattt tttagttgca gcattttttt actgctttac cttcgtgcag attttcgttt
    33361 tagaaccaaa agaaggttgg aaagaaacta tccaggttgc cttaaaaata tttactcagc
    33421 gacaagcacc catgatcctg acaatcatca ttattatggg atttttcttc ttactattgt
    33481 tgatttccaa tcgtttttgg tacgccttga ctgctacctt gatcattaac ttactgctca
    33541 ctatttcgac agtaatcaaa atggaaatgc gggaagagcc tgtctttcct tcagatttaa
    33601 aaatgctgac cggattgtca gaactattat cgatggttag cccagtctta ttaatcgtgg
    33661 gcggattgat ccttctccta ttattgatta ctagtattat tgtacaacgt agactacaaa
    33721 aacagtattc cttgaagatt cattggaaac gtcgatttat cagtatcgct gtattattag
    33781 gatgtttttc gggtgtcttt ttcattaatc acaaaaattc gccttctttc ttgctgttta
    33841 atttatttaa agtaaacaag actttcttta accagcaagg cgccgtaaaa gataacggac
    33901 cagtcattca attcctaaac aatatcgaca ttaaaatcat ggaagaacct gctggctatt
    33961 cgaaagaaaa aattaatgga ataatgaaaa agtacaacac aaaggcagat gaaatcaacc
    34021 aaacaagaag tgactggtta aacaatcaga cgatcgttct caatttaagt gaaagcttca
    34081 gtgatcctgc acgtgtccct aatctgacag tacctacaga ccctattcct tacatcaaaa
    34141 gcattataac agaaggaaca ggaggattga tgttatccgt cggttatggt ggcggaacag
    34201 ctaacatgga atgggaagga ctgacaggct tgagtatcag taacctgtct gcttcgttag
    34261 ttacacctta tacccagcta gtggagcgtc agaaaataag tccaaatatt accgatctat
    34321 tcgatgaaaa aatagccatc catcctttta cagctgctct ttatcgcaga aaacaagtgt
    34381 ttgataaatt tggttttgac aggttctatt atttagacag tccggataaa ttaacttata
    34441 cggataaaat agaacaaagc ccacgcatat cggatgattc agcatacaaa gaaaccttga
    34501 aagctttaca aagcaatacg gaaacgtcac aattcatcca attatccact atgcaaaacc
    34561 atatgcctta tgatgattac tatagtgaat tgaactacac tgctgaagga actgctgtca
    34621 ttcctaatag aagaaaagaa ttacaaactt atatgcaagg ccttcactat accgatacag
    34681 cagtaaaaaa attcatccaa gaaatcgaca aaatcgataa accgattacc tttgtttttt
    34741 atggtgacca tttacccgca atctatagtg ggaatgattc gaaaaaatat ggattagaac
    34801 agcaccagac agattatttc atttataaca acaagtatag tcgtgaacaa gcagctacgt
    34861 taaataaaga agttgttgct cctaataact ttggtgctat ggctcttgag catgcgaata
    34921 tcaaagtaac tccttactat gcgttgttga cagaagtatc taatcatcta cctgcattaa
    34981 caattgatcc tacagaaagc ttgtctaatc gttttaatgg aaaacaggtc tttgttacag
    35041 aggatagtca aattatccaa gaaaaaaatt taactgagaa acaaaaagaa attctagaag
    35101 attatcgtct gatacaatat gatcttgttg caggtaacca gtacagtgca acatgggcga
    35161 cacaaaaaat aaaagactaa caaataaact gagcaagggg ttgtgataaa agacatgtca
    35221 caaccccttg tttatctcat taatttgctt gtccataaac gatttgatta aagccatttt
    35281 tcaattcatt attcgctgtc tcgttgaagt aaagataatt atcgggattc ccctgatttt
    35341 gttgtgtcac caatactttt ggctgatttt gctgaaaccc gaatagatag acgtgctttt
    35401 tcagatatgg ttctgtctct gcatcggaat agacggctgt gatttgatag tctgcttgac
    35461 ctgtcccact ttctgaccat tctgcagaaa caggcactcc accaatagcc atcttccact
    35521 ccccgttcaa aatagcttga gggactttaa gaccatataa gtccacactc atttgattcg
    35581 tataactttt gtattgttgt cccattgttt ggccccattt ggtcataaat gcctctaatt
    35641 gtgcggattt gtctgcattc cacagtgttt gttcaacttg ttcgctgctt tctgaagagg
    35701 aagatgaagc ctctacagaa gaacttgaag tagatgtttg agttgtttca gtcgttttgg
    35761 aagactctga cgaagtagag gtatctgctg tttctgtact tgctgcagtt gacttgctct
    35821 ctgtgctagt tgttgtagta gttgcaactg ttgctttcgc tgtttctttt gttgattctt
    35881 ttttcgattc attcccgttg gtacaaccag ctaacaaaaa agctagacca attgttacta
    35941 aaatcctttt tttca
//
LOCUS       DAPBAF010000031        33787 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.031, whole genome shotgun sequence.
ACCESSION   DAPBAF010000031 DAPBAF010000000
VERSION     DAPBAF010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 33787)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33787)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33787
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.031"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            6..980
                     /gene="bsh"
                     /locus_tag="RD451_001720"
     CDS             6..980
                     /gene="bsh"
                     /locus_tag="RD451_001720"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HDT7566980.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTVTPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGEAKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
     gene            1710..2027
                     /locus_tag="RD451_001721"
     CDS             1710..2027
                     /locus_tag="RD451_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HDT7566981.1"
                     /translation="MLFYSNFILIVAILLLLNIWIFDRSRNASIGFRTKRSLSSKKNW
                     VYSQTIFYGGIVLISLLSSTLYSLNIIDVSTSNSISIIGIIIAAIITQLFLVFGEKKR
                     SKK"
     gene            complement(2231..2596)
                     /locus_tag="RD451_001722"
     CDS             complement(2231..2596)
                     /locus_tag="RD451_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566982.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            2804..3286
                     /locus_tag="RD451_001723"
     CDS             2804..3286
                     /locus_tag="RD451_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566983.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     FVVSRNFPALTVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSMFSLLPRLIIGP
                     NGLSESGLKDSAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            3483..4373
                     /locus_tag="RD451_001724"
     CDS             3483..4373
                     /locus_tag="RD451_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HDT7566984.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
     gene            4698..7169
                     /locus_tag="RD451_001725"
     CDS             4698..7169
                     /locus_tag="RD451_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HDT7566985.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGHQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKVIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLIKRNNTVAMTGDGVNDIL
                     AMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLVK
                     NIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNVM
                     EKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKFR
                     SQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLFE
                     RKNEKEQKPFSRVAKKFLSIFKREN"
     gene            complement(7272..9008)
                     /locus_tag="RD451_001726"
     CDS             complement(7272..9008)
                     /locus_tag="RD451_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HDT7566986.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNEDLLYVALPVKKSGQLEAILRIAEPTSGFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRACTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLNGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(9005..9709)
                     /locus_tag="RD451_001727"
     CDS             complement(9005..9709)
                     /locus_tag="RD451_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7566987.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            9840..10343
                     /locus_tag="RD451_001728"
     CDS             9840..10343
                     /locus_tag="RD451_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HDT7566988.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            10303..10641
                     /locus_tag="RD451_001729"
     CDS             10303..10641
                     /locus_tag="RD451_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HDT7566989.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            10662..12080
                     /gene="ffh"
                     /locus_tag="RD451_001730"
     CDS             10662..12080
                     /gene="ffh"
                     /locus_tag="RD451_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HDT7566990.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            12192..12770
                     /locus_tag="RD451_001731"
     CDS             12192..12770
                     /locus_tag="RD451_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HDT7566991.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            12774..13295
                     /locus_tag="RD451_001732"
     CDS             12774..13295
                     /locus_tag="RD451_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HDT7566992.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(13374..13928)
                     /locus_tag="RD451_001733"
     CDS             complement(13374..13928)
                     /locus_tag="RD451_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HDT7566993.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            14181..14456
                     /gene="rpsP"
                     /locus_tag="RD451_001734"
     CDS             14181..14456
                     /gene="rpsP"
                     /locus_tag="RD451_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HDT7566994.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            14468..14719
                     /locus_tag="RD451_001735"
     CDS             14468..14719
                     /locus_tag="RD451_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HDT7566995.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            14844..15635
                     /locus_tag="RD451_001736"
     CDS             14844..15635
                     /locus_tag="RD451_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7566996.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            15805..16326
                     /gene="rimM"
                     /locus_tag="RD451_001737"
     CDS             15805..16326
                     /gene="rimM"
                     /locus_tag="RD451_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HDT7566997.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            16316..17077
                     /gene="trmD"
                     /locus_tag="RD451_001738"
     CDS             16316..17077
                     /gene="trmD"
                     /locus_tag="RD451_001738"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HDT7566998.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            17213..17560
                     /gene="rplS"
                     /locus_tag="RD451_001739"
     CDS             17213..17560
                     /gene="rplS"
                     /locus_tag="RD451_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HDT7566999.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            17933..18595
                     /locus_tag="RD451_001740"
     CDS             17933..18595
                     /locus_tag="RD451_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010740290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567000.1"
                     /translation="MKQNDGRIIWKNQSELKLILTINEFIEKHGITSSRQYQKKLSEN
                     PNSAPSMWFINKKYGSWENLLISIGRENTGYGKWARMSEQELLEIVEAFIKCEKITSQ
                     RMYEQKSVGKNIPSLSTIKKMLGDIRPLFKEKNDGSRFTDFELLLELKNEIIRLKLQD
                     DLSMTKFRKLVQSPKLPSVDTIMKRTNKNWEELMAEIGFDYRRIKIYKQRNNLSKTKK
                     TK"
     gene            18674..21901
                     /gene="fss3"
                     /locus_tag="RD451_001741"
     CDS             18674..21901
                     /gene="fss3"
                     /locus_tag="RD451_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HDT7567001.1"
                     /translation="MKKPRFKNWRLLATLSLLCQTIGGSLGPTIAFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGVKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSEKAKLVSVLWKEAGTDVDTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     ESKINQAIADYQKKPSFHNSTVKTVLGQSTTVTDTNGLNLSEFDEVVENIANIDYRVN
                     GNQLVITPNANSKESGELTLKKSANTGTPVAYKMAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKETGNVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGAKVTIT
                     EKSVPAPYTIDTTPITATIKSGETISVTSKNTREKGQIILNKMGVETGTDLWNDKYSL
                     AGNTFAIRKDSPTGEIVQEMTTDEKGHAETPKEIANALELGTYYVTETKASNGFVNTF
                     KPVKVELNYVNQTVALVTSNVKGQNQEITGETTLTKEDKDTGNETQGKAEFKGAEYTL
                     FTAKDGQAVKWSEAFKPELVKGTKASDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYTLDETKYPVSIKKVDDNEKNAVITRDVTAKEQVIRFGFDFFKFAGSAAGTAETGF
                     NDLTFKVSPLEGTSEITDAEDEAITAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKADYTKSEYIFTITEKGQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLGTWKDGGKELTDLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     EATKAAQEKDEKAKPVVIAETTATLANKEKTGTWKILHKLTAEQVLDKTIVLFNYVYE
                     NKKPYEAGDDPVAKDASLNNQAQTVNCTVERHVSIQTKAHLEDGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDNTTKEIWKSGKIDYEVNDKEFTKTVLAEKVDT
                     SKYPEGTSFTFKEINYGKDGNINGKHNEDLKEKTQTLTPKKVPTTPSAPEQPEIPTVP
                     SDSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            22015..22329
                     /locus_tag="RD451_001742"
     CDS             22015..22329
                     /locus_tag="RD451_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HDT7567002.1"
                     /translation="MELKFVVPDMAETFGKIRYAGEGEVLTEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            22342..22716
                     /locus_tag="RD451_001743"
     CDS             22342..22716
                     /locus_tag="RD451_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HDT7567003.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTVSNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIMDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPDQGNSTNQNEGKK"
     gene            22726..23070
                     /locus_tag="RD451_001744"
     CDS             22726..23070
                     /locus_tag="RD451_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HDT7567004.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLTKALTYDEKMFLIMHQGLL
                     EVGNDAEEDFDVLNWLGEEESFFMVIEVNESLCREAETVLEEIGVEMPDAIEVFLKQL
                     VETKQLPIAVND"
     gene            23141..24493
                     /locus_tag="RD451_001745"
     CDS             23141..24493
                     /locus_tag="RD451_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HDT7567005.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQELRQFDI
                     SKLSLSTIEIVRSIKDLIYLLGSLVLSGSTMLLYIHFFQDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTKETISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDIIANRIGIDEVVAESGALRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFVLDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMTRSKAMKEMPNYKTGENYAFLGLPPNFLIFDEYVVYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFWVALGRMSELGYS
                     MMFGEVDKKFFMKRIKGRGYVDTGGSVISEFYTPLVPKGYDFLREISDIGGLNVNTEG
                     "
     gene            24553..25695
                     /locus_tag="RD451_001746"
     CDS             24553..25695
                     /locus_tag="RD451_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HDT7567006.1"
                     /translation="MTFLDLFAGIGGFCLGMEQAGHQCIGFCEIDDFARQSYKAIHDT
                     SKEVEMHDITSVSDEFIQSLGPVDILCGGFPCQAFSIAGKRQGFSDTRGTLFFEIARF
                     AAILQPKFLFLENVRGLLNHEGGATFETILRTLDGLGYDVEWQVLNSKAYVPQNRERI
                     FLIGHSRDACTEQVFPIIGSSPTSDQNIRNLLNINPSNRGMGGQVYGSDDVAPTLTGD
                     EGIKIALPVDDGISVAGMLLGNFEQGNRVYEITGTAPTLSTKQGGTKIMLRKNETEYQ
                     EVKPGNSVNLAFPNSTSRRGRLGKQSVHTLLTGDQQAVVTDQYQIRKLTPRECWRLQG
                     FPDWAFDRASQVNSDSQLYKQAGNSVTVPVIFDIARRLKEVKTDDL"
     gene            25720..25974
                     /locus_tag="RD451_001747"
     CDS             25720..25974
                     /locus_tag="RD451_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567007.1"
                     /translation="MIGKIQSDPELEEELYRLNFDIRKNGVKVPDDPYVIDEETDARM
                     ELNQVISELERIADFAKEPDIRQYLFEIKAELEIEGITAE"
     gene            26230..27414
                     /locus_tag="RD451_001748"
     CDS             26230..27414
                     /locus_tag="RD451_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HDT7567008.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATTCGLSRPYLNQIENGGV
                     TASTKTMRKIFDQLESFNPELPLTLLFDYVRIRFPTTDARKIIQEILHLKFDYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPDLTKKCQKEECISLFRTFKSYRSGELLKPDDKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAYHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNQKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNQTTYIQDMVNNTRLSDRHKKILEQQSMAIENL
                     II"
     gene            27411..27548
                     /locus_tag="RD451_001749"
     CDS             27411..27548
                     /locus_tag="RD451_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HDT7567009.1"
                     /translation="MKRGIVMEIVKDILLVFGGSMLGVTVMCLMHASAAADRAMEKKG
                     K"
     gene            27553..27774
                     /locus_tag="RD451_001750"
     CDS             27553..27774
                     /locus_tag="RD451_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567010.1"
                     /translation="MNFGQNLYQWFLTNAQSLVLLAIVVIGLFLGFKREFSKLIGFLV
                     IALIAVGLVFNASGVKDVLLNLFNRIVGA"
     gene            27787..28287
                     /locus_tag="RD451_001751"
     CDS             27787..28287
                     /locus_tag="RD451_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HDT7567011.1"
                     /translation="MEQIRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELKGTPIGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCNDMSDVAYYLIVEAGDLGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFELM"
     gene            28384..30231
                     /locus_tag="RD451_001752"
     CDS             28384..30231
                     /locus_tag="RD451_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HDT7567012.1"
                     /translation="MVGNKWYKCDLHIHSTASQCFQDKKVTAKEWVEECLNKGLDCVA
                     LTDHNTGENIDEYKKVAIENGLDFFPGVELTCGENGTHLLVLFDKSACTNDISDFLTK
                     MGIKREDWASAAACSMKSVLEVIDFAEHEGLLVIPAHIDEFNGISSAKFGNLGKIFES
                     ENIYAVQTVQKEFFENRSQMIPSSKRDTIYDSVNARYDGRVGKDTLESWYKSVVEAEK
                     NNMTFLSFSDNPHSKGNSKHGLWGIGTRYSYIKMKDEPDLGSLRDALMLGETRVHSDF
                     SNFSINENEVLLEKLSFSGTTLSTKEVVVEFSDNLTSIIGGRGTGKSCITRFLVYVLG
                     KEAELDQFSEIQSDYQNFAQIEHNGSGIFLKDTIVKLNIFYKGTKYQIIRTQDRHSIY
                     EFTQENGLVEKETERLRMISDKVSIYSQKQIYEISKNQTSILELLDGYNSDLISEYKN
                     EIETCVNEIRKLNWDIVSVKKEIQDKAKVELEIEDLKKQVEKLSHKSYKDVYDEYSKE
                     TDIYRELKRDVEALKEIPKNLTDSVDKIDFGNGIKVTDEIDEHRGELIKNLVTNRAKI
                     QTIINEMSDEIDSYRAELNKSDWKVNYNEVSKRYQRGIKNLVKSYLKMN"
     gene            30234..31130
                     /locus_tag="RD451_001753"
     CDS             30234..31130
                     /locus_tag="RD451_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDT7567013.1"
                     /translation="MLQNLDSLYQSLSKTEERLEEIIQQEIKLKDYQVEVDSAMSRMN
                     KSYQNFYSERSSSSREIFSDITGIEATIQPNRDFNNYVKELRACINKEDTFDSEFGSL
                     IDKLTKNSITNQDIYNDILDIRVSGESSIFSDKKLINSIRKLNDAQVLELQTLKPNDL
                     VVIRLELNGKKVSLSNASAGQKTSAILSMILAYGNSPLILDQPEDDLDSQLINNLIVR
                     SIITKKENRQILIVTHNANIPVNGDSEWLISMGDSKEISADQCGSVDEPNIKPRICTV
                     MEGGEDAFTNRAKRYGFKQIVE"
     gene            31180..31569
                     /locus_tag="RD451_001754"
     CDS             31180..31569
                     /locus_tag="RD451_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDT7567014.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEEVFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPSTLVRSVNYVSD"
     gene            31556..33058
                     /locus_tag="RD451_001755"
                     /pseudo
     CDS             31556..33058
                     /locus_tag="RD451_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            complement(33546..>33787)
                     /locus_tag="RD451_001756"
     CDS             complement(33546..>33787)
                     /locus_tag="RD451_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HDT7567015.1"
                     /translation="PPRKNMDKSEKLDHSLLGKQRKTVGTVFSSLEKLGCQNFNSRSV
                     KGLESRFESILLAYSVLLSRAQRRFEGTLRYSLGY"
BASE COUNT        11344 a         5677 c         7105 g         9661 t
ORIGIN      
        1 aaactatgtg tacgtctatt acttatgtaa caagtgatca ttattttgga aggaattttg
       61 attatgaaat atcttacaat gaagtagtca ctgttactcc aagaaattat aagttgaatt
      121 ttcgaaaggt aaatgatttg gatactcatt atgcaatgat tggtattgcc gctggtatag
      181 ctgactaccc tctttattac gatgcgacaa atgaaaaagg attgagtatg gctgggctaa
      241 atttttctgg gtatgctgat tataaagaaa tacaagaagg gaaagacaat gtatctcctt
      301 ttgaatttat tccttggatt ttaggacaat gctcaacagt aggagaagct aaaaaattgt
      361 taaaaaatat caatttagca aatataaatt atagtgatga acttccttta tcccctttac
      421 attggctatt agctgataaa gaaaaatcaa ttgtcattga aagtatgaaa gatggacttc
      481 atatatatga taaccctgtg ggcgttctta ccaataatcc ttcatttgac tatcaattat
      541 ttaatttaaa caattatcgt gtcttatcga gtgaaactcc taaaaataat ttttcaaatc
      601 aaataagttt gaatgcctat agccgcggta tgggagggat aggcttgcct ggagatttat
      661 cctcagtatc tcgttttgtt aaagcgactt ttacgaagct gaattctgta tctggagatt
      721 cagagtcaga aagtattagt caatttttcc atatcttagg ttcagtagaa caacaaaaag
      781 gtttgtgtga tgttggtgat ggaaaatatg aatatacaat ttattcttct tgttgcaatg
      841 ttgacaaagg aatctattat tatcgaacat atgaagacag tcaaattact gcaattgata
      901 tgaataaaga agacttagat agtcataagt taattagtta tccaattata gaaaaacaac
      961 aaattaaata tataaattag ttaatgtgtt gtgattgatt atttaatata gatataatac
     1021 aaaaaggcaa agatattttc aaaacatttt ttcttgatgt gatatccttg tcttttttgt
     1081 aatgttttta acttattgct tttgcaaaat ttatttacct gttttctgga tcaacgatag
     1141 tgtatattat gctatccttg tttggatttt aggacgttta aagaggcact tttttacata
     1201 acttaatcca tagacctttt aagcatgctg tgagataata ataaagaaga gtttaaagcg
     1261 caccccaaac cacttcccca taagtgtatt acgctttaaa ctcttttata tttgaattca
     1321 ctaagaagca taccatattt ttgaaaaaaa gtgagaaaaa aggcttataa ttaggattta
     1381 gagtaattaa ttagatgttt attttatagg actgatatta tagattacaa atagtatcgt
     1441 atttcgcaat cttaaaatta tcttcttact atgaataaga taataaaatt tgtatttgtc
     1501 ctttttaggt aacttatttt aatctatata cctttctgga tcaacgaaag tatactttat
     1561 atagtcataa cgccgatggt aactatgcac tgtaacgata atgctgctaa aatatctttt
     1621 tacgaaaaac atcacaagga aaaacttaac tatggtatta tctaaacata attttttcgg
     1681 tatttaatat ttaattagga gggaatattt tgctttttta tagtaatttt atcttaatag
     1741 tagcgatatt attacttctg aatatatgga tttttgatag gagtagaaat gcaagtatag
     1801 gttttagaac taaacgaagt ctgtcttcta aaaaaaattg ggtatactca caaactattt
     1861 tttatggagg aattgtttta attagtttac tttcttcaac actttattct ttgaatatta
     1921 tagatgtttc cacctcaaat tcaatatcta ttattggaat cattattgct gcaattatta
     1981 cacaactgtt tttagtgttt ggagagaaga aaagaagtaa aaaatagaaa aactagtgat
     2041 agttttggtg atagtgatat taaaaatcag aaaagataga aaaagcagga gatagataaa
     2101 atgctgatat ttcagcattt tttaagagta taaaagagaa aaaaagtaat aaatgtatac
     2161 atgatataag aaaaacatat atgtataaaa agaagaaagt agcttctctt tgtacatata
     2221 tggtttgttt ttatggatgc cgagcttttt tataagataa ggctaccgcc cataacgacc
     2281 caaggatttg tggaactaag taaatacctg caagaagcaa gatcagctgg gtcggtttta
     2341 aaggatgata gaagtaacgc cattcagtaa aattggcgca aaataaatag gaagtgacag
     2401 tagatataat attggcaatg aataaagata taatacgcct gttcctttga aaataatatc
     2461 cagcaaaaag agataaaaat atcaatgtga tgaacccgct tacggaatga taacgaaaat
     2521 caagcagtaa ggcgaaatgc acataaggaa caaaagataa aagcaacgga aggtttttcc
     2581 agcaagtttt tatcatcttt catcaccacc taacaagtgt tattattttg ttagttttat
     2641 tgtaaattga atcctgcaat aatcaattac tttttcatta tttctagatt aaatgaataa
     2701 actctcatgc cattatctct aaaaaaaaag tttttccccc taattttttt agatagaaaa
     2761 ttgtatagta tgatgagaga aaaagtagtt tgggggaacg ttaatgagaa gaaaagcagt
     2821 aatcgatcgg ctttatttat ttttttggtt ttttcctatc gttttgctac cttttacatg
     2881 ggtaaatgct gttgtacaag gtgcggagat attaggcctg atccaaggaa gcggatttgt
     2941 ggtttctagg aattttccag ctttgactgt tttctattta gtgataagtg taggtctctt
     3001 attaccaaaa tctctgatca atcactacaa ttggcagctg ctttactttt cttgcttatt
     3061 agtatttaca tctatgtttt ctttgctgcc tcgcttgatt atcggcccta atggtttgag
     3121 cgagagtgga ttgaaggatt cagcttattc ctccatgtat ttcttgacga tcaaaccatg
     3181 gttctattta gtaattgcct catttattct tgcaacattt ttttacttct ggacagaaat
     3241 caggataaaa agtgaacgat ctgtatctat aaaaaataac tattgatggt ggatcatcag
     3301 taaaaaagca tatgagctgc gtaaaatgca tgtttctcat atgctttttt tattattatg
     3361 taaagaatgc gaaaaacgtt tacatgattt ttacataact taactatatt tttacagcaa
     3421 ccatacgagg gatttacagt cgactgataa actttagttg taaataagaa aggagcaata
     3481 aaatgaaaaa agtattgttt actctaggta tgatgggaat tcttttagcc ggatgcggct
     3541 caggatcagg aaatacagat ggctctgcca cacaaaataa ttcaagtgac tcaaatgaac
     3601 aagtaaaaat cgttgcggta ggttcgacag cattacagcc gttagtcgat gcagcacaag
     3661 aaagctttgt acaagaaaat ccaaattatc aaatctctgt acaaggagga ggaagcggaa
     3721 ctggtttgag ccaagtcgaa gctggagcag ttactatcgg aaactctgat gtatttgcag
     3781 aagaaagaga cggagttgat gcttcaaaat tagtggatca taaagtagca gtggtcggga
     3841 tggcgccaat cgtcaataaa gatacagatg tcaaagatat caccaaacag gaattgattg
     3901 atatctttac aggaaaaatc actaactgga aggaagttgg cgggaaagat caaaaaatca
     3961 acgtcgtgaa ccgtgcaaac ggcagcggta cccgcgcgac attcgaaaaa tggggactgg
     4021 atggtgctac ccctgtgcag tcccaagaac aagattcatc aggaacagtt cggcagctgg
     4081 taagtcaaac accaggagca atcagctatt tagctttctc atatctcgat gattccacac
     4141 aagcactaag tatcgacggt gtagaaccaa aagaagagaa tgtagcagat aacagctggg
     4201 gaatctggtc atatgaacat atgtacacga acggaaaacc ttcccctgaa gtccaaaaat
     4261 tcttagacta catgatgaca gaagaaatcc aagaaggacc tgtcaaagaa ttgggctatt
     4321 taccaatcac aatgatggaa gtagaacgtg atcacgaagg aaatatcaaa taactagcag
     4381 ataaacatgc cacggtagtc gttactatta aggaaaaatc aactatgttt cccacatata
     4441 catttttcct ttaattgtga aaaatagttc ctcatatttt gccgtttttt gagctaatac
     4501 cgagggtcag ctgattaaac accgtttatt cgaaaaaaag agctacgaca tagaactgtc
     4561 gtagctcttt ttttgctata tgacaggaat gaaaggtgtt tgcaagctta atgtgaggaa
     4621 cactttccat atctgttcta tactggatag gagaagtttg gaaatatcca gaaaacgaaa
     4681 tcaatcgagg tagccacatg aagaataaat ggataaatcg aagtaaaaaa aagaaagtaa
     4741 cacaaagatc atcagataaa gtcatccgtc tttttccatc gtataaagaa ggattaacgg
     4801 cagatcaagt caaggaacga atagaaaaag gtgcagcaaa taattcagtc gatcccacat
     4861 tcaaaacaaa tcagcaaatc gtattggaaa acatatttac gtatttcaat ttgatctttc
     4921 ttatcttagc cattttgctt tgtttagtag aatcctataa gaacttgact tttttaccag
     4981 ttatcatagc caatacagga atcgccattt ttcaggaaat tcgatccaaa aagatcttgg
     5041 acgaactaaa tgttttaaat acagcaaaag tcaatgtcat acgggacggg atagaacaaa
     5101 caatagatat agaagacctt gtaatagatg acattgttat tttagagact ggacatcaaa
     5161 ttccagcaga tgcagaggtc gtggaaggaa aactgcaagt taatgaggct ttattgacag
     5221 gcgaagcaga tgaaataacc aaagaaatag gcgatccatt aatgtccggc agtttcattg
     5281 tttccggaaa agcttacgcc cgattagaca aagttggagc agattcgtat atttcccagc
     5341 tgacagtcaa agccaagaca atgggagaag gagaacagtc ggagatgatt gcttctctta
     5401 atcaattgat caaatggatt gggatcatca ttattcctat cggtatcctg cttttttctc
     5461 aaagttactt ttttaatgga aacacgatca aagaaagtgt cgttgcaatg gaagcagcat
     5521 tgatcggtat gatacctgaa ggactgtact tgctgacgac gattgcatta gcattaagtg
     5581 cgactaaact agcaaagcaa agagttcttt tacacaatat gaaaagcatt gagacattgg
     5641 caagggtaaa tgtcctttgt gtagataaaa caggaacgat cacagaaaat aaaatgtctg
     5701 ttcaaaaagt gatcgtctct aaaaaacaag aaataatcag tcagtcagat caattggaag
     5761 catgcattgc tgactatgca aaagcgatgg caggagacaa tgcaacaatg gaagctgtta
     5821 aagcatattt tacaaaaacc actgatcaat cctatcacca tgttattcct ttttcttctg
     5881 tccaaaaatt cagcagtgta gcgttggcag acaaggtgta tgttttagga gcgcccgaaa
     5941 tggttttgcg cgatcaattg ccggaatatg cggaagagtt tgtttctttc gctgaaaaag
     6001 gctatcgcgt gttggtcttt ggtgtgtacg atgggattct tgaagaacca gtattgacag
     6061 aagcagtcac accattaggc tatattctga ttgctaatcc tatcagaaaa gaagcaagag
     6121 ccacatttga ttacttcaaa aaacagcaag tagccatcaa agtgatttct ggagataatc
     6181 cgctcaccgt atccaatgta gctgtccaag cagggatttc acatgctgat cagtacgttg
     6241 atgcatctaa attatcagaa gaagaatatg aagcagctgt cgaaaaatat acagtttttg
     6301 gacgcgtcaa gccagaacaa aagaaaatct tcgttcaatt gataaagcgt aacaatacag
     6361 tagctatgac aggtgatggc gtgaatgata ttctagccat gaaagaagca gactgcagta
     6421 tagcgatggc ttccggaaat gaagccgcca tgcaggcctc acaagtggtc ttacttgatt
     6481 ctgacttttc acgcatgcca gaagttgttg cagaaggacg gcgcgttgtg aacaatattg
     6541 agcgatcagc cagcttgttt ttagtgaaga atattttctc ctttttgctc tcactgtttt
     6601 cagtgatctt tgctctgacc tatcctttag aaccatcaca aatcacattg attagtttgt
     6661 ttactatcgg acttccatct ttcttgcttg ctctagaaga aaacaaaaag cgaatcagag
     6721 ggaaattcat catgaatgtg atggaaaaag ctgtgccagg tggactaaca gatatgatcg
     6781 tagtcggtgc gttggtgatc tgcggggtga ctttgaatct aaataaaaca gatgtttcta
     6841 cagcatctac catgcttttg attgcagtag ggttcctcgt tctctataaa atctgttcac
     6901 cgctgaataa attcagaagt cagatcattc ttttctgtgc tagcggtaac tttttttcgg
     6961 tcatcttttt gcataagctg ttttcaatca ccggtatctc agctgtatca cttttgctgt
     7021 tgagcattct atttttctcg gcagattcga tttttaggca tttgaccaca ttggtagaat
     7081 atttgtttga acgtaaaaat gaaaaagagc aaaagccgtt tagtcgcgta gctaaaaaat
     7141 ttctatcgat atttaaacga gaaaattgac gaaaagtatc tcaaaaaaga gtaaaaaaga
     7201 acaaccactc gtgtatcttt cgaagcagga tgagtcatcc aactttaaaa cgcacgagca
     7261 gttgctcttt tttacatttt cggaatggta acggtgaaag tcgaacctgt tccaagatga
     7321 ctgtctacag taatcgtacc attaaggagt tgcacgtagt cttttacaat cgctaaccct
     7381 aatccggtcc cgcctgaatg tcggcttcgc gccttgtcta cgcggtaaaa acgctcaaag
     7441 atccgttcct gatcctcaat gtcgatacct ataccaaagt cttggacaga aaacgataga
     7501 tcatctgttg cctgatagcg gataataatc tcgctgtcgc tttttgaata ttggacagca
     7561 ttttcaatca gatttttgat aattggataa aggatatctg ttttagtagt aaatggttcg
     7621 ttctttccaa tcaatcgaat cgtcaaccgt ttcttttcga tgattggctg ataattttga
     7681 acgatttgct ggaaataagg ttctgtataa attgtctgga tctcgtaaga attctcgcca
     7741 tcttttgaca gctggatgat ttcccgaatc agtttatcta accggatcgc atctttttgc
     7801 atgatctcaa gaaaagaagt cagagtttgc gggtcatctt ttgcaccatc cagtaaagtc
     7861 tcggtaaaac caatcagtga agtcacagga gtttttaatt cgtgagagac gttgccaacg
     7921 aaatcctttt gtagcttttc taaacgtcgc actttcgtta agtcatacgc cacccctaga
     7981 atctgtccgg taccttctga attagtaaag tagcgcaaac tcaagtctaa tgtctgccga
     8041 ccttctgtaa gggtgatctc ctgatggatc agcggatgct caggagtcac ttgatgaatc
     8101 agctgaatga gttttggctc ttgaatgact tctgtgtacc gctgttcagg ttgatagctt
     8161 accacgttta aatgtagctg catctttgga ttaagcagta gtaaacgaga atcagcatca
     8221 tcaatcagga atacgccaat catcagttcg ttcagtaacg tatataattg ctcttctgtg
     8281 gtagtacacg cccgatacat cttactcatt tgttcgctca acgcattaat cgtctgatac
     8341 aattcttccc attgatcggg tgtttgcatg attacttccg cctgattagg attttgcacc
     8401 atttttttta gtacgggcag cacggttttc aatggctggt ttttttgata gatcagataa
     8461 tagatcattc ctgcaagaac aaggaagaaa gacagaaaga agaaaaagac ccaacggcga
     8521 aaactctcag ttctcggtaa aaaaccgctt gtcggttctg cgatacgtaa aatggcttct
     8581 aactggccac tttttttgac tggtaatgcg acatataaaa gatcctcatt caaagtagta
     8641 cttttgcgca aagcgctacc taggttccca ccattcaata cggctttgat ttcgggacgg
     8701 gagtttcgct gttcattcaa tgtttcattg tttgtgtcaa ataagatctt tccagtagca
     8761 tccattaaag taatccgttc gttcgactga tggacgaatt cttccaaagc agttttgttt
     8821 tgcgctgctt ggaggttttc gacatctaat tgccggatca gcagttgtgc tttttttgtc
     8881 aggtagcttt cttgctgttc cacgatctgc tgttgaaaat aatgggaaat caattgccag
     8941 ccaccaaaaa acaaactaac taaaagaata agaaagaaga gacgttcata aatttttttc
     9001 catttcatcg ttttggttcc tgaaacttat agccaaatcc tctaatagtc accaagtact
     9061 ttggatgttt tggatctcgc tcgatttttt ctcgcaaatg actaacgtgt acatctacga
     9121 ttcggctttg tcctgcgaag tcaaaattcc aaatgcggtc tagcaatgtg tctcggtcga
     9181 tcacacggtc ttttcgtttc atgaaataaa caagtaattc aaattctttc ggtgttagtt
     9241 caatcagatg gtcgtctacg gtcacttgat aattggtcaa atcagcagtg atttgtccaa
     9301 tcgatagata ttcaggctca gcttcatctt ttgattgctt acgaggttca atccgtctga
     9361 atattgcttt catacgggct aatacttcgc gaggactaaa tggtttggtc aaatagtcgt
     9421 cagcacctat ttctaggcca atgatccgat ccacttggtc atctttagcc gtcagcatca
     9481 aaatcggtgt ttcatttttt tcttgacgca gccgctgagt gatctccatg ccatccatcg
     9541 ttggaagcat cacatctaaa atgatgaaat caaatgattg ttctaatgct aattctaatc
     9601 cttcgcctcc atctgtggca ctggttacct tgtagccttc tttttccaaa ttgaacgtca
     9661 agagcgttac aatagaaggt tcatcatcaa caactagtat ttttttcatt caaatctcct
     9721 ttaaataggt ttcattctgt ttatatttta gcatagaatc agtacaaagg gctattttac
     9781 aaaagaaata aatggtataa taggaaggca ctttgctgaa tagaaaggaa gagcagtcaa
     9841 tgattggaat cagtgcatgt ttaggcggtc tggcctgtcg ctatgatgga cagaaaaaag
     9901 aagtaccaga attgatggaa ctagttgaaa ctggagaagc tgtcatggtc tgtccagaag
     9961 tgatcggcgg attaccaatt cctagagatc ccgctgaaat cattggtgga aatggattcg
    10021 atgtgtggaa agatcaagca aaagtatgga cgacaagcgg cgaagatgta acggaagcgt
    10081 acaaaaatgg cgcgatcaaa gcctatcaaa aattgcagga aaaacacatt gatctagtca
    10141 tcatgaagga aaaaagccct tcatgcggaa cccattcgat ttatgacgga agtttttccg
    10201 gaataaaaaa aaatggtgcc ggagtggcta ctgcttattt tattcagcaa aaaatgactg
    10261 tgctctctga tgaagaatgg ctgaaaacta gaggtgagca gaatggaaat cgaaaagacc
    10321 aatcgaatga acgcgctctt tgaattttat tcgaccttat tgacagaaaa acaaatgaac
    10381 tacatggaat tatattatgc agatgatttt tcattaggtg agatcgcgga agaatacgaa
    10441 gtaagccgac aagcagtata tgacaatatc aagcggacaa gcaagatctt ggaggattat
    10501 gaaaaaaaac tccatctttt ttctaattat attgttcgag aacaggtatt ggaaaatatg
    10561 actgcatata ttacagataa gtacccggaa gataaaaaac tacttgaata tgtacagcaa
    10621 attcaagcaa tcgaagaata aataaaagga atgaagaaaa tatggcattt gaaagcttaa
    10681 ctgaacgtct ccagcaggcg atgggaaaaa taagaaaaaa aggaaaagta tcagaagctg
    10741 acgtaaaaga aatgatgcgg gaaatccgcc ttgccttact agaagccgat gttaacttgc
    10801 aagtagtcaa agattttact aagcgcgtac gcgaacgtgc ggtaggggca gaagtgctgg
    10861 aaagtttatc acctgcacaa caaatcgtaa aaatcgttga tgaagaattg acgatcacac
    10921 ttggttctga aacagcagag ttaaataaat caccaaaaat accaactgtt atcatgatgg
    10981 ctggtcttca aggggcaggt aaaacgacct ttactggtaa attagccaat tatttaaaga
    11041 aaaatgaaaa tgctcgtccg ctcctaatcg caggggacgt atatcgacca gctgcgatcg
    11101 accaattgaa agtattaggt caacagctag acgttcctgt atttgatatg ggaactgaag
    11161 tcagcccggt agagatcgtc cgtcaaggga tggagttagc aaaagaaaag aaaaacgact
    11221 atgtattgat cgatacggca ggacgtctgc atatcgatga aacattgatg gatgagttga
    11281 aacaaatcaa agaattgacg caaccaaatg agattttgct tgttgtcgat gccatgactg
    11341 gtcaagatgc cgtcaacgta gctgatagct tcaaccagca attaggtatt acaggggtcg
    11401 tcatcactaa acttgatggg gatactcgag gcggggcagc actatcgatc cgctcagtga
    11461 caggcgcacc aatcaaattc atcggttctg gtgaaaaatt gactgactta gaagtattcc
    11521 acccagatcg tatggctagc cgtatccttg gtatggggga tatgctgaca ttgattgaaa
    11581 aagcgcagca agactacgac gagaaaaaag cggaagaact tgcacagaaa atgcgggaaa
    11641 attcattcga tttcaatgac tttattgaac agcttgatca agtgatgggt atgggcccac
    11701 tggaagatct aatcaaaatg atcccaggaa tgaatcaagt ccctggaatc gaaaacgtca
    11761 aggtagatcc aaaagatgtt gaacgcaaaa aagcgatggt ttattctatg acgccagcag
    11821 aaagagcaaa tcctgatctg ttgaacccaa gccgtcgtcg ccgaattgct gccggttctg
    11881 gaaacagtgt tgttgaagtg aatcgaatga tcaaacaatt caaggaatca agaaaaatga
    11941 tgcagcaaat gtccaaaggg gatatgaaca tcccaggtat ggaccaaatg tttggttcag
    12001 gcgtcaaagg aaaactaggc aaaatggcga tgaatcgaat gatcaagaaa aataagaaga
    12061 aaaagaaaaa acggaaataa gatgaaaaaa acagcttcgg tacagactga aaatgtctac
    12121 tgccggagct tttctatcag caatttttat tctttactaa tacaattact ctaaacgaag
    12181 aggtggcaca gatgagatgt ccgtggagtg aacaaacaga aagtatgcgg caatatcatg
    12241 atactgtctg gggtgttcct gaatatgatg accaaaagct gttccgaaaa ttgatgcttg
    12301 atattaatca agccggattg agctggcaga cgattttaaa taaaagtgaa gcattcgatg
    12361 aagcatatga tcgattcgat atcaaaaaag tcgcaaatta tggagaaaca aaaatcagtg
    12421 aactaatgga aaacaaagga attattcgta accgaagaaa aatcgaagca gccgtccaaa
    12481 acgccaaagc agtcttgaaa attcaagaag aaatcggcag tttttcagag tatctttggt
    12541 cgttttctaa tggaaaaatc gttgattctt cttatcattc acaagaagaa gtcccaacaa
    12601 caagtcctct ttcagatgaa ttagcaaaag atctaaagaa aagaggattt aaatttatcg
    12661 gaagcacaac aatctatgct tttttagaag ctgtcgggat catcaatgat caccttgaca
    12721 gttgtttccg caaagaagag gtcgtacgta tcggcagaaa gggcgaataa agcatgcgaa
    12781 aaatcatatt ttatggtgct ataagtttag atggctattt ggcaacgaaa acggatgatc
    12841 ttcaatggct ttttgacact ccaacaggta agcaaactac ttatgaagct ttttatgaaa
    12901 caatcgatac gaccatcatg ggcagaaaaa cttatcagga agcaaaaaaa tatttggaga
    12961 ccgaagcaat ttatccagag aaaaagaatt tcgttttttc cacccacgca caattacaat
    13021 tgccagatgc tgaggtcgta aacgaagatc ctgttgcttt tctaaaaaat ctacaaatga
    13081 cagaaggaaa agatatctgg gttgtgggtg gcggtcgatt gatcaaaccg ctattggaac
    13141 atcaaatgat tgatgaatgg tatatccaga ttacccctgt attattaggg gacgggattc
    13201 ctttattcca aaaaggaaca tatgaagcgc gttttgaaat gctagacacg acacgattcg
    13261 gtgaatttat cgaattgcat tatgtacgaa agtagaagta aataaaataa aaaaggcaac
    13321 tatatgcaga aatgtcctgt acatagttgc cttttttatt accgttatgc tttttactct
    13381 gttaatttgt tagaaaaatc tagatacgca tctaaaatcg tttggaagaa acttaatgtt
    13441 ccttcaacga tattaccatt ttcatcaatt agattcgcaa cgtttccgat atatgcttcc
    13501 ggttgctgca aggttggcac attcaaaaag acaagtgatt ggcgtagatg gtggtttgcg
    13561 ccaaagccgc cgatcccacc tggtgatgca gtaacgacta aacctggttt atgatcccaa
    13621 acactgtgtc cataaggtct tgagcctaca tctaaagcat ttttcaatac tgctggcaca
    13681 gaacggttgt attcaggagt aacgaaaacg acaccgtcta gtcccctcac ttcctcacga
    13741 aaacgagtcc attcagcagg agcctgttct ggagtttcga gatcctcatt gtaaaatggc
    13801 agatcatcga tttttacaaa tacactttcg tacccttcag gaagcaattt cgcaaaagct
    13861 tctgctactt ttttgttgta agaatctttt cttaaactac caataaaaaa tccaattttt
    13921 tttgtcatac gatttttcct ccttcaaact atctataata atcttacaaa agataagtaa
    13981 ctggagcaaa taaaaacact tactgacaaa agctacatag aagatagatt acttattttt
    14041 aacaaaaaag aagtctaaaa tcttctattt tctaaaaaaa atcgaattta atcaagctgt
    14101 aaagaaaaaa agctttacag ggtaaaaaaa aactgttaca ctacatcttg tgaataaaac
    14161 aatggaggtg gaaataaata atggcagtta aaatccgttt aaaacgtatg ggttctaaaa
    14221 agagtccgtt ttaccgtatc gtcgtagctg attcacgttc tcctcgtgat ggacgtttca
    14281 tcgaaactgt aggtacttac aatcctttga aagaccctgc agaagtagtt ttaaaagaag
    14341 acttagttct tgactggtta tcaaaaggtg cacaaccttc tgacactgta cgtaacatcc
    14401 tttcaaaaga aggcgttatg caaaaacacc acgaagctaa attctcaaag aaataaggtg
    14461 accggatatg aaagatttaa gcgacttagt cttaacaatc gttcgtccgc tagtcactta
    14521 tcctgatcaa gtcaagttag acgtcgtaga gtcgaaagac ttttacgagt acaatctaac
    14581 agtggctcct gaagatattg gccgtatcat tggaaaacaa gggcgtgttg ctaaagcaat
    14641 ccgcacaatc gtttacggtg ttcggatcaa tgcaccgaaa aaagtgcgtt tgaatatcat
    14701 cgatgataag gaaaagtaaa taaacgtgct gtactcgaat tttcgagtgc agcttttttg
    14761 ttttttttat taattgaaga aatgattatt tggcaaaaca agcaagaaag cgtatcctta
    14821 taggaggagg gagtgaacag ccaatgagaa agaaaatgtt atttattcca tttgctctat
    14881 tgttaagcgc ttgtagttcg gttactcaag aatcagacaa tacacatcta tcaagcagta
    14941 tatctgaaac tgttaccagt ccagaaaaaa gtagtaccaa aacggcttcc accactgaac
    15001 aaacaatggc tacctcaaat aatgagaaaa agactgcttt agaccagttg aaagaacaac
    15061 agccaaatgt tcccatgcct ctagatgtac cagtctcttc aggctatctc aatatcgcag
    15121 cgacacatac aaagcaaggt tattctattt tatattacag aacagatcgt cccctcgggt
    15181 tgaatgctga cgaattgaat caagaaacgc ctattgcaac ctatctatat caatatgggt
    15241 ttgcttctag tcaagaaaca atccaagttt tgcagccatt tgagatcgac acaaatggtc
    15301 agcaagtgga cttaggttct cgaatcacag ggtatcagca aggtgcagca ggttcaagtt
    15361 ttcttgaatg gcaagaagga aactggcgta ttcgaatccg tgggaataat atagaaggcc
    15421 aagatccctt actattagct aaagaaatcg tagcttattt ggaagaaaac agtctaccag
    15481 cacctgaaca atttggtaaa attactgttg atatgggtga tacgacgaat cgagccgtag
    15541 aagtaagctg gcaagaaccg aaaaatgcct atacgatcac tcatcaagat cctatgtctg
    15601 cgttgaagat ggcagtttct atgaagaggt tgtgaaatca gcgcgctgat ctgagcccat
    15661 catttaactc caagtcacag gaagtaatca aaaatagcac gccgcatttt tgcataattt
    15721 tggcttaata ccttaaaaga aaactagaat tgcctcttca cacatgctaa aataaaacag
    15781 acaaaaaaga aatggggata taagttgact gaatacttga atgtaggaaa aatcgtaaac
    15841 acacaaggta tcaaaggcga agtccgtgtt atctcaacaa cggatttccc agaagaacgt
    15901 tacaaaaaag gaacggtgct aacactattc caagacggaa aagcacctgt ggaattaaca
    15961 gtcaaaagtc atcgcaaaca taaaaatttt gacttattga gttttgaagg acatccttct
    16021 atcaatgatg tggaaaaata tcgggatggc atattaaaag tgtcaaaaga caactctgta
    16081 gatctagctg aaaatgaatt ctattaccat gagatcatcg gtctgcatgt attagaagat
    16141 ggaactgagt taggtaaagt aaaagaaatc ttgtcaccag gtgccaatga tgtttgggtc
    16201 gttcaacgtc cgaaaaaagc tgatatattg cttccatata tcgcttctgt cgtcaaagaa
    16261 gtcgatttag aagctggagt ggtccgtgta gaaattccag aaggactgat tgacgatgaa
    16321 gattgatgta ttgactttat ttccaagaat gtttgaaggt cctatggggg aatccatcat
    16381 cggtaaggct gtagataaag gattattaga tatcaatatc tctaacttcc gcgattattc
    16441 agataacaaa catcagacag tagatgatta tccatacggc ggtggagcag gtatgctgct
    16501 caaagtccag cccatctatg ataacatcca agccattgaa aaagctgcac cggatgtcaa
    16561 aaaaagagta attcttcttg acccagctgg taaacgattc gatcagaaaa tggcagaaga
    16621 attttcacaa gaagaacact tagtattcat ttgtggtcat tatgagggat atgatgaacg
    16681 tatccgcaca ttagtgacag atgaagtttc cttaggagat tatgtcctta ctgggggaga
    16741 attaggtgcg atggtcatga tcgatgcaac agttcggctt ttgccagatg tgttagggaa
    16801 tcagacttca gctcaaacgg attcttattc aaccggttta ttggaacatc cccaatatac
    16861 tcgcccggca gaatataaag ggatgaaagt accagaagta ttgacaaatg gaaatcataa
    16921 attgattgaa gaatggcaat taaaagaatc actaagaagg acctatcaac gtcggcctga
    16981 tcttttggaa acacttgaat ggacacctca aatgacgaaa tttttagaag aaatcaagaa
    17041 agaagaacaa gaaaaaacag cagatgaagc caagtgactt tttctaaaat cttctttaca
    17101 gtaggttgat aatatgttag tattttatgg tgagtgcaaa agcacttaac tattacgata
    17161 ttccgctgtg agaaaagctc ataagaatat ttggaataag gagaagaaaa ccatgaatcc
    17221 attaatcgaa gaattaacaa aagaacaatt acgttctgac atcccagcgt tccgccctgg
    17281 tgacactgtg cgtgttcacg caaaagttgt tgaaggtact cgtgaacgta tccagttatt
    17341 tgaaggtgtt gttatcaaac gccgcggtgc tggaatcagc gaaacttata cagtacgtaa
    17401 agtttctaac ggagtgggcg ttgaacgtac attcccattg catacaccac gtgttgcaaa
    17461 aatcgaagta gttcgctacg gtaaagtacg tcgtgcaaaa ttgtactacc tacgtgcatt
    17521 acacggaaaa gctgctcgta tcaaagaaat cagaagataa acacggaaaa cttccttgga
    17581 aatctgaaat ttgtgaaaag tccttgtata tcaagggctt tttctttttt ctctatcaca
    17641 gttttaagcc atttttggct gttttggacc atttttcaat catattccct taaaaattgt
    17701 cctagattgt ccgacattga ctatcagtgt cgtcaaaata gggcaaaatt tagtagtcag
    17761 cttgacgaca aatataatac gaaaaatacc aaaacattta ccgaatttag caacttttga
    17821 acccaagttt ctcaaagggt cagctattag caaaaaagac aaaacatgta cttttctact
    17881 aaaaagttga tgtgataggc ttctatctaa ataactatta ggagttttta tcgtgaagca
    17941 aaatgatgga cgtatcattt ggaaaaatca aagtgagtta aaactgattt taacaattaa
    18001 tgaattcatc gaaaaacacg gaattacatc tagccgtcaa taccagaaaa agctatcaga
    18061 aaatccaaat tctgcaccaa gtatgtggtt cattaacaaa aaatatggat catgggagaa
    18121 tttattgatt agtataggac gagaaaatac tgggtatgga aaatgggcta gaatgtcaga
    18181 acaagaatta ttggaaatag tagaagcctt tattaagtgc gagaagataa cctctcaacg
    18241 aatgtacgaa caaaaatcag tagggaagaa tattccttca cttagtacca ttaaaaagat
    18301 gttaggagat atacgtccac tttttaaaga aaaaaatgat ggatctcgat ttactgattt
    18361 cgaactgctg ttagaactaa aaaatgaaat aatccgatta aaactacagg atgatttatc
    18421 aatgacaaag tttcgaaaac tagttcaatc cccaaaacta ccatcagttg atacaattat
    18481 gaaaagaacg aacaaaaatt gggaggaatt gatggcagag attggatttg attatcgaag
    18541 aatcaaaatt tataagcaga gaaacaacct atccaagaca aagaaaacta aatagtatca
    18601 ctctaaatca gacgttcaaa attaaaattt ggacgtcttt tttattaccc aaaaacgaaa
    18661 ggagatttat tttatgaaaa agccaagatt taagaattgg cgtttgctcg caacactgag
    18721 tctattatgc caaacaattg gtggatcgct tggcccaacg attgcctttg ctgatgaaat
    18781 tactcatcca caaacggtaa ctgtggaatt ggatttggct caccagtatg ctgtcgaagg
    18841 tacatttagc gatggtcgtc ccatgtcaga agttaccgtt ccgcactatg cagtttacaa
    18901 tggtgtgaag caagatattt tctgtattga gccaggggtg ccgatttaca atgagttcac
    18961 tcctggttat gagaaaaatc cattgcctga tatgtcggag aaagcgaaat tagtttccgt
    19021 tttatggaag gaagctggta cggatgtgga tacacatatt gtggcccaga agatgatttg
    19081 gcaagaagtt aatggctaca cgcttcactc aattaaacgt tctgatggta gtgcagtaaa
    19141 tatcgcagcc attgagtcaa aaatcaatca agccattgcg gattatcaaa agaaaccaag
    19201 cttccataac tccacagtga aaaccgtgtt aggtcaatcg actactgtga cagatacgaa
    19261 cggcttgaat ttatcggagt ttgatgaagt tgtcgagaat atcgcaaata ttgattatcg
    19321 tgtgaacggc aatcaactag tgattactcc aaatgccaat tcaaaagaga gtggtgaatt
    19381 aaccctaaag aagtcagcta atacaggaac accggtagct tataaaatgg ctggtcaaca
    19441 aactttgatg gcgggggcaa ttgataagcc caatacctac acaatcaaaa ttgatgtgga
    19501 aactgagggt tctttgaaga ttaaaaaagt cgataaagaa acaggaaatg ttgtaccggg
    19561 aaccgttttc catttagact ttggaaaaac attacctgca aaagacgtga ccaccgataa
    19621 agaaggcatt gcgacattgg atgagattcc tcatggcgcg aaagtaacca ttactgaaaa
    19681 atcagtgcca gctccttata cgattgacac tacaccaatc accgcaacca ttaaatctgg
    19741 tgagactatt tctgtgactt caaaaaatac tcgcgaaaaa ggtcaaatca ttttgaataa
    19801 aatgggggtg gaaacaggaa ctgatctttg gaacgacaaa tactcattag ccggaaatac
    19861 gtttgccatt cgcaaagaca gtccaaccgg tgaaattgtc caagaaatga ccacggatga
    19921 aaaaggtcat gcggaaacac caaaagagat tgccaatgcg ttggaattgg gaacctatta
    19981 tgtgaccgaa accaaagcta gtaatggctt tgtgaatacc tttaaaccag taaaagtcga
    20041 attgaactat gtcaatcaaa ccgtggctct tgttaccagt aacgtaaaag ggcaaaacca
    20101 agaaatcact ggtgaaacca ctttgacaaa agaagacaaa gataccggta atgaaactca
    20161 aggtaaagct gagtttaaag gagctgaata tactctcttt actgcaaaag atggtcaagc
    20221 ggtcaaatgg agtgaggctt ttaaaccaga gttagtgaag ggaacgaaag cttctgatga
    20281 aacggtgact ttgactttag atgaaaagaa tcaagttgct gttaaacact tagcgattaa
    20341 tgagtattac tggcaagaaa ccaaagcacc tgaaggatat accttggatg aaacaaagta
    20401 ccctgtttcc atcaaaaagg tggatgataa cgaaaaaaat gccgtgatta cccgagatgt
    20461 tacggcaaaa gaacaagtca ttcgctttgg ctttgatttc tttaaatttg ctggatcagc
    20521 tgctgggact gccgaaactg gcttcaatga tctgaccttt aaagtatcgc cattggaagg
    20581 aaccagtgag attacagatg ccgaagatga agcaattaca gcttataacg agcaactagg
    20641 ttttgatggc tatggcaagt ttgaaaatct tccttatggg gattatttac ttgaagaagt
    20701 agaggctcca gaaggatttc aaaaaattac gccattagaa atccgttcta cttttaaaga
    20761 aaataaagcg gattacacta agagtgaata catttttacg attaccgaaa aaggacaaaa
    20821 acaaccaatt aaaacggtga ccgttcctta cgagaaactg acgaataaag cattttctgt
    20881 tagcttgaat cgtttgatgc tctatgattt acctgaagaa gaagatagct taacttctct
    20941 tgggacttgg aaagacggag gcaaagaatt gacagacctt gattctaccg agctagttga
    21001 taaattgagc tataacttgc atgaaatcaa agaagactgg tatgtggtag cgcaagccat
    21061 tgatgtggaa gcgacaaaag ctgcccaaga aaaagatgaa aaagccaaac cagtggtaat
    21121 tgccgaaaca accgcaacgt tggcgaataa agagaaaaca ggaacttgga aaattttgca
    21181 taaattaacc gcagaacaag ttttggataa aaccatcgtc ttattcaact atgtgtatga
    21241 aaacaagaaa ccctatgaag caggtgatga tccagtagcg aaagatgcta gcttgaacaa
    21301 tcaagcccaa actgtcaatt gtacggtgga acgccatgtt tccatccaaa caaaagccca
    21361 cctagaagat ggttcgcaaa cctttactca tggggatgtg gtggatatgt tcgatgatgt
    21421 gtcgattacc catgatgtac tggatggctc aaaagaagct tttgaaacaa ttctgtatgc
    21481 attacttccg gataatacga ccaaagaaat ttggaaatct ggcaaaattg attatgaagt
    21541 gaatgacaaa gaattcacta aaaccgtact tgcggaaaaa gtggacacaa gtaaatatcc
    21601 agaaggtaca agttttacct tcaaagaaat taactatggc aaagacggaa acatcaatgg
    21661 gaaacacaat gaggatctaa aagaaaaaac tcaaacttta acacctaaaa aagttccgac
    21721 aacaccaagt gcaccagaac aaccggaaat accaactgtt ccaagtgact ctcaagaatc
    21781 tagtcctaca gtaaagacat tcccacaaac aggggagaaa aattctaatg ttctgctgtt
    21841 tattgggttt accttgatct ttgcgactgc tgggtattat ttctggaatc gccgaaacta
    21901 aggtgatgtg atgaaacaac taaataggaa aaaccaacgt gcgcgaccgc ctcctaaaaa
    21961 aagtggtcgc gctatttttg tatccaaaac taaaaatgaa aagaggaaaa gaagatggaa
    22021 ttgaaatttg ttgtgccaga tatggccgaa acctttggaa agataaggta tgccggcgaa
    22081 ggcgaagttt taactgaagg atatgggcgg aatactacag taattggtcg tagttatcat
    22141 ttgtattcca gtaagcaacg agccgatgat attgaagtgg tggtagctgc ggaagccggc
    22201 gaaaaggatt ttgatcaaga tcaaccacta aaagccgtga atccccattt ggttgccaaa
    22261 ggctatgaga ttgagaatcg tgggtttacc gactacgtgt tgtatgtcga tgatttagtg
    22321 aaagcatagg aggaaaagaa gatgagatta acagaaggta ttgttgtaga ttcaggacta
    22381 acgtttggga aattacgatt ttccgcatta cgccgagaag tacggaagca aaatgaggat
    22441 ggaacggtta gtaacgaggt aaaagaacgg acttataatt tgaaatcctc tgcgcaaggt
    22501 cgaatgatcc aagttagtat cccagcaaat gtacccttac gcgagtttgc ctatgacgca
    22561 gaggtagagt tggtcaatcc aatcatggat acggtcgcca attatgtttt ccgagaagga
    22621 actactgtca attggttcat taaggccgat gatttagtct tgaaacgaca accagatcag
    22681 ggaaattcta caaaccaaaa tgaaggaaag aaataggtga agcgtatgga aattaatgtt
    22741 gaacatattt tagattgtct cgatcaatat ggaaaaggtg agctaacgga ggaacaactc
    22801 actaaagcat taacctatga tgaaaaaatg tttctgatta tgcatcaagg gttactggaa
    22861 gtaggtaacg atgccgaaga agattttgat gtactgaatt ggttagggga agaagagtcc
    22921 ttctttatgg ttatcgaagt aaatgaaagt ctatgtcgag aagccgaaac cgtattggaa
    22981 gaaattggtg tggaaatgcc ggatgccatt gaagtttttt taaagcaact agtggaaacg
    23041 aaacaactcc ctatagcagt aaatgactag cataactgct tgaaattgga tcaatgaaat
    23101 cctatgaagc ttttttcgat tggaggtgga aaccataaaa atgtacaaag ggcatcgtat
    23161 acgggcagga gatcagcact tggtttatca ctttgttctt ggctggctac tcgctctgtt
    23221 catcggttgg atgagcgtct tttattttca agagcttaga caatttgata tttctaagct
    23281 atcactttct actatagaaa tcgttcgttc tataaaagat ttaatctatt tgctaggaag
    23341 tctcgttctt tcaggaagca cgatgttgct ttatatacac ttttttcagg atcattggcg
    23401 cagtttgtgg catcgacaaa agctagcccg gatgattcta gaaaatcatt ggtacgaagt
    23461 aaaacaaact cagagtgaag gatttttcaa agacctcaat agtagtcgaa ccaaagagac
    23521 aatcagttac ttccccaaaa tctattaccg tatgaaggat ggtttacttt ctattcgcgt
    23581 tcaaatttca ctgggaaaat atcaagatca gcttttaaag ctggaaaaga agttagaaag
    23641 tggtctatat tgtgaactag tagaaaagga actcaaagac tcctatgtgg agtacacttt
    23701 actgtatgat ataattgcca atcgaattgg gatagacgaa gtagtggcag aaagtggggc
    23761 tttgcgattg atgaaaaatc aagtatgggc ttatgattct ttacctcata tgttaatcgc
    23821 tggcggcaca ggtggtggga agacttactt tttactcact atcatcgagg ctttattaaa
    23881 atctgatgcc gagctttttg ttcttgatcc caaaaatgcg gacttagccg atttaggtac
    23941 ggtaatgcct catgtctatt cccaaaagga ggaaatttct gcttgtgtgg aagatttcta
    24001 tgagcgcatg atgactcgta gcaaggcaat gaaagaaatg cccaactaca aaacaggaga
    24061 gaattatgcg tttcttggac ttccaccaaa ctttttaatc tttgatgaat acgtggttta
    24121 tatggaaatg ttaacgacga aggaaagtgc ggtgattttg aataagctca aacaaatcgt
    24181 gatgttaggt cgtcaatctg gtttctttct gattctagct tgtcaaagac cggatgcgaa
    24241 atatttagga gacgggattc gcgatcaatt taatttctgg gtggctttgg gtcgtatgag
    24301 tgaactggga tattccatga tgtttggcga ggttgataaa aaattcttta tgaagcgtat
    24361 caaaggtcga ggctatgtag atacgggagg gagtgtgatt agtgagtttt atacgccact
    24421 tgtaccaaaa ggatatgatt tcttaaggga aattagcgac attggtggat taaacgttaa
    24481 tacggaagga taaaataata gtatgtagcc taggagtgtc aagaatcctg ggcttttttt
    24541 acgaggtgat ttatgacatt tttagattta ttcgctggga ttggtggctt ttgcttaggt
    24601 atggaacaag cgggtcacca gtgtatcggc ttttgtgaaa ttgatgattt tgctcgccag
    24661 agttataagg caatccatga tacaagtaag gaggtggaaa tgcatgacat cacaagtgta
    24721 tcagacgagt ttattcaatc tctcggacca gtggatatcc tttgcggtgg atttccgtgc
    24781 caagcttttt caattgcggg aaagcggcaa ggattttccg atactcgagg tactttattc
    24841 tttgaaatcg ctcggttcgc cgctattctc caacctaagt ttttattcct tgagaacgtc
    24901 cggggattac tcaatcacga aggaggggct acgttcgaga cgatcctccg aacgctggat
    24961 ggattggggt atgatgtgga atggcaagtg cttaactcaa aggcctacgt tccccaaaac
    25021 cgtgagcgga tcttccttat cggacattct cgagacgcat gtaccgaaca agtatttcct
    25081 atcattggat cgtctccaac atctgatcaa aacatcagaa acttattaaa tatcaaccct
    25141 tccaatcgag gaatgggggg acaagtctat gggtcagatg acgtagcgcc taccttgacc
    25201 ggtgatgaag gaatcaaaat cgcattgccg gtagatgatg gaatttctgt agcgggtatg
    25261 ttactgggaa attttgaaca aggcaatcgg gtttatgaga taactggaac agcgcctact
    25321 ttgtcaacga aacaaggcgg aacgaagatc atgcttcgga aaaacgaaac agaatatcaa
    25381 gaggtgaagc cagggaacag tgtgaacctg gcttttccta attccacaag tcgtcgaggc
    25441 cgtctgggaa aacaaagtgt gcatacctta ttaacaggag accaacaagc agtcgtcacg
    25501 gatcagtatc aaattcgaaa gttaacacct agggagtgct ggcggcttca gggctttccg
    25561 gactgggctt ttgatcgagc ttctcaagtc aattcagata gtcagttgta taagcaggct
    25621 ggaaattctg taacagttcc ggtcattttt gatattgcta gaagattaaa ggaggtaaaa
    25681 acagatgatt tatgatgagt tgattgggga atctactggg tgattggcaa gattcagtca
    25741 gatccggaat tggaagaaga actgtaccgg ctcaattttg atattcgcaa aaacggggtg
    25801 aaagtccctg atgatccgta tgtaattgat gaggaaacgg atgctcgaat ggagctgaat
    25861 caagtcatca gtgaattgga acgaattgcg gactttgcta aagaacctga tatccgccaa
    25921 tacttgtttg agataaaagc agagttggaa attgagggta ttaccgcgga gtaacggcca
    25981 aataaaccac tgataggcac tgaccgcggg ggatttgcga agcagaaatc ctccgtggtg
    26041 ctgtgcctgt ttatggacgg cgttagccgg ccatgatgtc tcaccccccg tatctaacag
    26101 gggggtacaa aaacacaaaa aataagcaag caacgataag gaatggctgt cctatcaagg
    26161 ataataagca atttgtgtag atgttaactg atttgaaaaa gttaacacct taaatttgga
    26221 ggtgagaact tggcacaaag gaatttagat tatcggctat taaaagaccg gcgtaatgaa
    26281 tatggcgttt cacaaaataa attagctacg acttgtggac ttagtcgccc gtacttaaat
    26341 cagatagaaa atggtggcgt aaccgcatcg acaaaaacca tgaggaaaat ttttgaccaa
    26401 ctggaaagtt tcaatcccga gttaccttta acgttactgt ttgactatgt aaggattcgc
    26461 tttcccacaa cggatgcgag gaaaatcatt caagagattc tccatttgaa atttgattat
    26521 atgctccacg aagattacgc cttttactcc tatcaagaac aatatgttat gggagatatt
    26581 gtggtgatgt tgtcacatga agaagataaa ggcgtccttt tagaattaaa gggtcgtggt
    26641 tgtcggcagt ttgaaacttt tttactcgcc caaaagcgta gctggtatga ctttttcgaa
    26701 gattgtctaa aagccggtgg cgtgatgaaa cgcttagacc tggcaatcaa tgatcgagtt
    26761 ggcctgttag atattcctga tttaacgaaa aaatgtcaga aggaagaatg tatctccttg
    26821 tttcgtacct tcaaaagcta tcgttccggg gaactgttga aacctgatga taaagatggt
    26881 atgggcaata ctttgtatat tggcagtctt aagagtgagg tctatttctg tttgtacgaa
    26941 aaagactatg agcaatatat caagttaggg attcctttag accagaccga aacgaaaaat
    27001 cgttttgaaa tccgactgaa aaatgatcga gcttatcatg caattcaaga tttgttaaaa
    27061 ggtcgcagta ttgaaagtac cacattttcc attattaacc ggtacttgcg atttgcggat
    27121 aaggtggaag gcaaaaggcg aactaactgg cccttgaatg aacaatgggg gcgcttcatt
    27181 ggacggaatc agaaggaaat tcaattaact tctgaaccga agccttatac cattgaacga
    27241 acgttgaact ggcttggacg acaagtcgcc cctacgtgga agatggccaa ggagttggat
    27301 cggttgaatc agacaacgta cattcaggat atggtaaata atactcgact atcagaccgg
    27361 cacaaaaaga ttttggagca acaaagtatg gcaattgaaa atttgattat atgaaaagag
    27421 gaatcgtgat ggaaattgtg aaagatattt tattggtgtt tggtggcagt atgcttggtg
    27481 ttactgtgat gtgcttgatg catgcaagtg cagcggcgga ccgagcaatg gaaaagaaag
    27541 gaaagtgatg aaatgaattt cggtcaaaat ttgtatcaat ggtttttaac caatgctcaa
    27601 tctttagtct tactagcgat tgtggtcatt ggtttgtttt taggatttaa acgcgagttt
    27661 tccaaactga ttggcttctt ggtgattgct ttgattgcgg taggtctggt ctttaatgct
    27721 tctggtgtga aggatgtctt actcaatttg tttaaccgaa ttgtcggtgc ctgaggggga
    27781 atcacaatgg aacagatacg tgtttatatt gcgaaccttg gaaaatacaa tgaaggtgag
    27841 ttggtggggg catggtttac cccacccgtc gattttgatg aagtgaaaga acggattgga
    27901 ttaaatgacg aatatgaaga gtacgcaatt catgattatg aactgccttt tgagattgat
    27961 gagtatacac caattgagga aattaatcgg ttgtgtggtt tagcggaaga gcttaaagga
    28021 acgccaattg gtgaggtcgc ttcagagatt caacatgcct tcttcaattc tttcgaggaa
    28081 atggtagagc atgtggatga tatcatctat tatcccgatt gtaatgacat gagtgatgta
    28141 gcgtattact tgattgtaga agctggtgat ttaggcgaag taccagaaca cttgaagacg
    28201 tatattgatt ttgatgcgtg tggtcgagac ttggagattg gcgggaatta tttggttacg
    28261 agtcgagggg tttttgaact aatgtaaatc atttgttaga attgaccaga aatttctatc
    28321 gtacttttac ttttctattt gatatactga aatagaaaat atttgttgat aggggtgtta
    28381 ctaatggttg gcaataagtg gtacaaatgt gatcttcata ttcattcaac tgcgagtcag
    28441 tgctttcagg ataaaaaggt tactgctaag gaatgggtag aagaatgttt aaacaaagga
    28501 ctcgattgtg ttgcattaac tgatcacaat acaggggaaa atattgatga atataagaaa
    28561 gtggctatcg aaaatggctt agattttttt cctggagtgg aattaacgtg tggagaaaat
    28621 ggaactcatt tactagtcct atttgataaa agtgcatgta caaatgatat ctctgatttc
    28681 ttaaccaaga tgggtataaa aagagaggat tgggccagcg ctgcagcttg ctcaatgaaa
    28741 tcagttttag aagttattga ttttgctgag cacgagggct tgctcgttat tcctgcacat
    28801 atagatgagt ttaatggaat ttcttcagca aaatttggaa atctaggaaa gatatttgaa
    28861 tcagaaaata tatatgcagt acagacggtt caaaaagaat tttttgaaaa tcgctcacaa
    28921 atgattccct catctaagcg tgacactatc tatgatagtg tgaatgccag atatgatggt
    28981 agagttggaa aagatacttt ggaatcttgg tataaatcag ttgttgaggc agaaaaaaat
    29041 aatatgacat ttcttagctt ttctgataac ccacactcga aaggaaattc aaaacatgga
    29101 ctttggggaa taggcacaag atattcctat ataaaaatga aggacgaacc tgacttggga
    29161 tcacttcgcg atgctttaat gctaggcgaa actcgagttc attctgattt ttctaatttc
    29221 tccattaatg aaaatgaagt tttattggaa aaattaagct tttctgggac cactcttagc
    29281 acaaaagaag ttgtagtcga attcagcgat aatttaactt caattattgg aggaagagga
    29341 acaggcaaat cttgtattac aagattcttg gtctatgtcc ttggaaagga agcagaactt
    29401 gatcaatttt ctgaaataca aagtgattat cagaactttg cacaaattga acataatggc
    29461 tctggaatat ttttgaagga tacaattgtg aaactgaata ttttctataa ggggacaaaa
    29521 tatcaaataa taagaacaca ggatagacat tctatttatg aatttacaca agagaatggt
    29581 ctggttgaaa aagaaacaga acggttgaga atgatttccg ataaggtgag tatatactct
    29641 caaaaacaaa tttatgaaat ttcaaaaaat caaactagta tactagaatt actagatgga
    29701 tataactctg atttgatttc agagtataaa aatgagattg aaacatgtgt aaacgaaata
    29761 agaaaattaa attgggatat tgtttctgtg aaaaaagaaa tacaagataa ggcgaaggta
    29821 gagcttgaaa ttgaagattt aaaaaaacaa gtagaaaagc tatctcataa gagttataaa
    29881 gatgtttatg atgagtattc aaaagagaca gatatttata gggaactgaa acgtgatgtg
    29941 gaggcactta aggaaattcc caaaaatcta actgatagtg ttgacaaaat tgactttggc
    30001 aatggtataa aagttacaga cgaaattgat gaacaccgcg gagaattgat taagaattta
    30061 gtgaccaatc gggctaagat tcaaacaata attaatgaaa tgtcagatga aattgatagt
    30121 tatagagcag agctgaataa atcagattgg aaagttaact ataatgaggt ttcaaagagg
    30181 tatcaaagag gtatcaaaaa cttagtgaag agttatctca agatgaatta aaaatgttac
    30241 aaaaccttga ttctttatat caatctttat caaaaactga agagcgattg gaagaaatta
    30301 ttcaacaaga aataaagctt aaagattacc aagttgaggt tgactcagca atgtcaagaa
    30361 tgaataaatc atatcaaaat ttctattctg agagaagtag ttcctcgcgc gaaatttttt
    30421 ctgatattac aggaatagag gctactattc aaccaaatag ggatttcaat aattatgtta
    30481 aagagctcag agcttgtatt aataaggagg acacttttga cagtgagttt ggatctctta
    30541 ttgataagct gacaaaaaat tccattacta atcaagatat atataatgac atacttgata
    30601 taagagttag tggggaaagt agtatttttt cagataaaaa attaatcaat tctataagaa
    30661 aattgaatga tgcacaagtt cttgaattac aaacccttaa gccaaatgat ttagtagtta
    30721 tccgacttga actaaatgga aaaaaagtta gtttatcgaa tgctagtgct ggtcaaaaga
    30781 catctgcaat tctttctatg attttggcgt atggaaattc accactcata ttggatcagc
    30841 ctgaagatga tttggatagt caattaatta ataacttaat cgtaagaagt atcattacaa
    30901 aaaaggaaaa cagacaaatt ttaattgtaa ctcataatgc aaatatccca gttaatggtg
    30961 attcagaatg gttgattagc atgggagatt caaaagaaat atcggctgat cagtgcgggt
    31021 cggtagatga acccaatatc aagccaagaa tatgtactgt gatggaaggt ggcgaggatg
    31081 cttttacaaa tagagcgaaa cgctatggtt ttaaacaaat tgtagaataa cactagaggg
    31141 tgagacatat tattatgtcc gcccttttta ggaggaaaaa tgaaaaaaat aaaaagctat
    31201 accagtatct gggcagttga aaaagtcatt tacgcaatca atgattttca gttgcctttt
    31261 cctgtgactt ttaaccaaat ggcttggttc gttttatctt tactgtttgt catcgtattt
    31321 gcccatgtgc ctccactatc tatgatagag gaggtctttt taaaatactt aggcataccg
    31381 gtggctgtca cttggtttat gtcgcaaaag acgtttgatg gcaagaaacc actgggattt
    31441 ttacgatcct ttatcagcta tcacttgcga tttaaggtga cttttgcagg aaagaaagtc
    31501 aaagaacaga agaaacgatg ggatgaaccc agtactcttg taaggagtgt gaactatgta
    31561 tccgattaag tatattgaaa ataatctcgt ctttaaccaa gaaggcgagt gttttgccta
    31621 ctatgaatta gtgccttaca attactcctt tttgtcaccc gaacagaaat ttcaagtgca
    31681 tgataacttt cgccaactaa ttgcgcaaaa tcgtgaaggc aagatccatg cgttacaaat
    31741 tgccacagaa agtagtattc gcgccacaca agaacgatca aaaaaagaaa ttaccggtag
    31801 actcaaagaa gtagcgaaac aacgaattga tatacagaca gatgcattag tatccatgat
    31861 tggcgatagt cagattgatt atcgcttttt tattggcttt aaactaattg cgacagatga
    31921 agaagtcaat ctaaagagtc tcaagaaatc tttcttttct gggcttcaag aatttgtcta
    31981 tggagtgaat catcatttga tgggcgattt tgtttcctta tccaatgaag aaattcgctg
    32041 ctattctaag cttgaaaaat taatggaaag caaattggct cgaagattta aagtcaggcg
    32101 agtcacaccg agtgacctga cgtatttgat tgaacatatt tatggcgaaa aagggatacc
    32161 gtttgaagaa tacgaatttc agctaccaaa gaaaaagcta aaatcagaaa cactggtgaa
    32221 acgttatgac ttattacgtc caaatcgttg tttaattgaa gaaaaaccaa ggtgcttacg
    32281 gatggaacat gagaatcatg agtcgtacgt agcgtattta acaattaata caattgtggg
    32341 ggagatggaa tttccttcct cagaactttt ctattaccag caacaacaat ttacattccc
    32401 aatcgacaca agtatgaatg tagagattgt gacgaataaa aaggctttag ctaccgttcg
    32461 taataagaaa aaagaactga aagatttaga caatcatgct taccaatctg acaatgaaac
    32521 gaattccaat gtcttagatg ctttggattc cgtggatgaa ttggaaacca ccttggatca
    32581 gtcaaaagaa tctatgtaca aactgagtta tgtggttcga gtgagtgccg aatcagtgga
    32641 tgaactaaag cgacgctgtg atgaagtgct cgatttttat gatgatacca atgtaaaact
    32701 agtccggccc tttggcgata tgatggggct acatgaagaa ttcttaccct taagtaaacg
    32761 atatatgaac gactatattc agtatgttac gtctgatttt ttggcggggc ttggttttgg
    32821 ggctactcag atgctaggag aattagaagg gatttacttt ggctacaatg tggatacagg
    32881 tcgtaatgtt tacctgaaac cggcattggc ttcacaagga gtcaagggtt cagtaaccaa
    32941 tgcgctggcc gccgctttcc tgggttctct tggtggaggt aaatccttta gtaacaatct
    33001 cttagtctac tatgctgttt tgttcggtgg tcaagctgtg attgtcgatc caaaaggggg
    33061 tgcgaaacgt tcctacttga aaagagtagg cacagcactt cattaaatca atatttaatg
    33121 tgtgttggag aactaaacac acgaatagtc gaatgacggg gtaacgccct gaaaggctac
    33181 tttaatactc tgactggcag aaacttgagt aaacaaggct ctgtcagaag ctcggtgaag
    33241 tcggcagaca gacaccgtaa cagataatgc tgacgaaaga ttcccagagg tgggcgttgt
    33301 gtcctatatg ccggaagtct ataaaatatc tatggttaga atgtagatga gaggtctact
    33361 gacgaatcct tgaatgtaca ggtctatatc ggggctggat agaaatgtcc agtgacacaa
    33421 acagtgtcgc tactgtgggt gagtaagact ccgcatttat gaaaatccat ataacgttaa
    33481 aggcgttatc aaggtagcag gcttatagag gaaacctaag gatatacccg tggtgctagt
    33541 taattttaat atcctaaaga atatctcaaa gttccttcaa aacgtcgttg tgctcgactt
    33601 aatagaacac tgtaagccag taatatgctt tcaaatctac tctctagccc tttaacagaa
    33661 cgtgagttga aattttgaca acctaatttt tctaaggaag aaaaaacagt cccaactgtt
    33721 tttctttgtt ttccaagtaa gctgtggtct agtttttctg atttatccat gtttttacgt
    33781 ggcggaa
//
LOCUS       DAPBAF010000032        33672 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.032, whole genome shotgun sequence.
ACCESSION   DAPBAF010000032 DAPBAF010000000
VERSION     DAPBAF010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 33672)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33672)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33672
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.032"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            103..273
                     /locus_tag="RD451_001757"
     CDS             103..273
                     /locus_tag="RD451_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567016.1"
                     /translation="MKWKEKVDEAAEKLYDLVKSEKYNIEVNIPKKGGKAVQVKSKRP
                     TNHTKKWMAKNR"
     gene            493..1200
                     /locus_tag="RD451_001758"
     CDS             493..1200
                     /locus_tag="RD451_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDT7567017.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRGDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(1259..1903)
                     /locus_tag="RD451_001759"
     CDS             complement(1259..1903)
                     /locus_tag="RD451_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HDT7567018.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDQAKSFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGVPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSADHFKESIIELLNGQVQFEEGSVSYHEQLITDHI"
     gene            2030..2317
                     /locus_tag="RD451_001760"
     CDS             2030..2317
                     /locus_tag="RD451_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567019.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            2425..2745
                     /locus_tag="RD451_001761"
     CDS             2425..2745
                     /locus_tag="RD451_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDT7567020.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIT
                     LIGE"
     gene            2826..4139
                     /locus_tag="RD451_001762"
     CDS             2826..4139
                     /locus_tag="RD451_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HDT7567021.1"
                     /translation="MNHFWGRRLLTRDIEAIDCEEVNLPNYEKIAAVERLGNWILCHR
                     CGMRTSVIDGQLADYGYFCTHCLYLGRCDTQQDLYLFDQPEAKPREVVFFWTGQLTEK
                     QTEISKRILCHSEKRHHLIWAVTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNEL
                     FLRYRYVFPEEKITLLHGNTATAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYN
                     GDAGLAHAVQTAIKPDGRFIYLSATPDKKLLKEIKQTFDIHKLALRFHRRLLPEPVLV
                     FMNNWRQKCKNKKKIKSLVRIIHQLIKENHILLFCPSITMMHRLKATLQEALPRYEIT
                     DVSSRDNQRAEKVQKMREAKYDILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQ
                     IAGRADRKGPYTNSQVYFFYEEKTAAIRKACQEIKEMNEEGKKML"
     gene            4136..4855
                     /locus_tag="RD451_001763"
     CDS             4136..4855
                     /locus_tag="RD451_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HDT7567022.1"
                     /translation="MRCSCCSKDIFQNLTFSEIIGVSKYRLPQTCSVCRAQFHLLETR
                     GCSGCQKPIHFNLESTKKKVKSIPVYCSDCQEWKKKYPTYDFQHRAFFVYDENMKAWL
                     NQYKFMGDIRLAGTFAYKWTQIKKEYPTYIYCPIPLSEKRRTERGFNQVSEMLKAARI
                     PFQMLLKREKHLLAQAKNTRKERLEMPQPFELAVTFSKIQNKKILIIDDVYTTGQTLF
                     HAADCLQVAQPKIIRTISLAR"
     gene            4983..5534
                     /gene="raiA"
                     /locus_tag="RD451_001764"
     CDS             4983..5534
                     /gene="raiA"
                     /locus_tag="RD451_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HDT7567023.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTADAAALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
     gene            5756..8290
                     /gene="secA"
                     /locus_tag="RD451_001765"
     CDS             5756..8290
                     /gene="secA"
                     /locus_tag="RD451_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HDT7567024.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDVQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKAFLDRMKIGEE
                     DAVIQSKMLTKQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIIDFAGSTLVHEDSITLADIEGKTSQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKNAN"
     gene            8416..9517
                     /gene="prfB"
                     /locus_tag="RD451_001766"
     CDS             join(8416..8487,8489..9517)
                     /gene="prfB"
                     /locus_tag="RD451_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_139124933.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HDT7567025.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRRSLDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAAMQEEAETRI
                     NALDEKMKTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            9622..10308
                     /gene="ftsE"
                     /locus_tag="RD451_001767"
     CDS             9622..10308
                     /gene="ftsE"
                     /locus_tag="RD451_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HDT7567026.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            10292..11185
                     /locus_tag="RD451_001768"
     CDS             10292..11185
                     /locus_tag="RD451_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7567027.1"
                     /translation="MDTMIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFM
                     AVIMNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELK
                     KIQNEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEEAADLKNVSRSDYGGASSD
                     RIFQIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRW
                     PFFLEGGWIGLIGAILPILIITFGYAWFFQLINPSLLRSHYSLIRPQNIVWKINLLMV
                     GIGVIIGSLGSIISMRRFLKF"
     gene            11337..12785
                     /gene="cls"
                     /locus_tag="RD451_001769"
     CDS             11337..12785
                     /gene="cls"
                     /locus_tag="RD451_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HDT7567028.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWLLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDALGE
                     EVRDALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEVAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGKIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYTLQNRFLM
                     DWNSQHTKEVGYSPKFFPSIHTTGDIAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLVYDERMASRVRKAFFEDS
                     KISTHLTKEMYENRGIIIKMKEGLARLISPLL"
     gene            13122..13979
                     /locus_tag="RD451_001770"
     CDS             13122..13979
                     /locus_tag="RD451_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HDT7567029.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQTENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            14094..15014
                     /gene="pstC"
                     /locus_tag="RD451_001771"
     CDS             14094..15014
                     /gene="pstC"
                     /locus_tag="RD451_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HDT7567030.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            15014..15898
                     /gene="pstA"
                     /locus_tag="RD451_001772"
     CDS             15014..15898
                     /gene="pstA"
                     /locus_tag="RD451_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HDT7567031.1"
                     /translation="MNAKRSDKIATGVLYIVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVMKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            15913..16719
                     /gene="pstB"
                     /locus_tag="RD451_001773"
     CDS             15913..16719
                     /gene="pstB"
                     /locus_tag="RD451_001773"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002408906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HDT7567032.1"
                     /translation="MKKYNWNETNVITMPKEKEVALYTDDIHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYQGVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            16735..17493
                     /locus_tag="RD451_001774"
     CDS             16735..17493
                     /locus_tag="RD451_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HDT7567033.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGIDLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWDDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            17506..18183
                     /gene="phoU"
                     /locus_tag="RD451_001775"
     CDS             17506..18183
                     /gene="phoU"
                     /locus_tag="RD451_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HDT7567034.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            18406..19437
                     /locus_tag="RD451_001776"
     CDS             18406..19437
                     /locus_tag="RD451_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HDT7567035.1"
                     /translation="MQKKISIITIFFICVLTSWVIQHQAALYEVPVIEIEKVRIKEDH
                     QLITGKLMNSDQKGESIYLSVPYQKNQIETANIKARQMYLVQMHGDEWQLVAKKNDGW
                     LFFFTSIFIGAMLLIGGKQGLFALGSLIINIVLLLLLLLIFTKTEGISLLNKSILFVV
                     IGMIISILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNHWKDQGLRYEELNYLTRP
                     YRSVFLSSVLIGTAGGTLDTVITVIATLEELTKRQPEITAKQLWLSGRQVGRDVIGSM
                     TNILLFVYISGSVPSLLLYLGNQWSFKETIEQHLSLEFLRVIAGSLGIVLSIPISVLF
                     FLTVRRLKR"
     gene            19434..20201
                     /locus_tag="RD451_001777"
     CDS             19434..20201
                     /locus_tag="RD451_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HDT7567036.1"
                     /translation="MNVLIILVGILAISVLLIGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILALSVIGFLLIAVVILFFINGYNLKMRAAFVSILIFLFCFLLLLPITDFLAI
                     QGFTSVELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     LSFYQLRHSSFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDIPFQQVINEKSFVL
                     EYTMAILTTLSALIVLPLTCVTTAYLFTKKKEQLKME"
     gene            20301..21869
                     /gene="liaX"
                     /locus_tag="RD451_001778"
     CDS             20301..21869
                     /gene="liaX"
                     /locus_tag="RD451_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HDT7567037.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDKASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQALEAEIKELEASGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDDEIAQVQL
                     STTTGSIYLKDTDK"
     gene            22166..22486
                     /locus_tag="RD451_001779"
     CDS             22166..22486
                     /locus_tag="RD451_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HDT7567038.1"
                     /translation="MMKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVA
                     FGSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTREQTKKRKEAEKIDDDE
                     WSDF"
     gene            22486..22836
                     /locus_tag="RD451_001780"
     CDS             22486..22836
                     /locus_tag="RD451_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HDT7567039.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALLVAILM
                     SLVNVIVSEHNSRK"
     gene            23003..23941
                     /locus_tag="RD451_001781"
     CDS             23003..23941
                     /locus_tag="RD451_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HDT7567040.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            23956..24786
                     /locus_tag="RD451_001782"
     CDS             23956..24786
                     /locus_tag="RD451_001782"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HDT7567041.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLFLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGNLPDYDRSLGKNQQII
                     "
     gene            24830..25855
                     /locus_tag="RD451_001783"
     CDS             24830..25855
                     /locus_tag="RD451_001783"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HDT7567042.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHYLPDSIQAFTNMEDAVKDADAVLFVIPTKAIRSVAKELVPKLNTKPVI
                     IHASKGLEQGTHKRISDILLEEIPAEKRKAVVVLSGPSHAEEVAKHDITTITAASTDA
                     KAAKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGIGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQMMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            25870..26808
                     /gene="galU"
                     /locus_tag="RD451_001784"
     CDS             25870..26808
                     /gene="galU"
                     /locus_tag="RD451_001784"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HDT7567043.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYIMSLGKTLEAEGSKINHNPKGITEIKEEKKK"
     gene            26933..27373
                     /locus_tag="RD451_001785"
     CDS             26933..27373
                     /locus_tag="RD451_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HDT7567044.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTQDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIVTKVGGIGKTTAKATVAGKVGGTAMKFFKNKKHTETTGGK"
     gene            27376..27978
                     /locus_tag="RD451_001786"
     CDS             27376..27978
                     /locus_tag="RD451_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HDT7567045.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSSELTGIAKEKAQGLSQQAGDLAGNVKQKVSESAEEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDLKKPADELGSIAKDTSEDIMIDVKDAADKAGETVNEG
                     MSEAKPVADDTKEMLKMAKEDAKEAKKEMKDTMTDSTTNH"
     gene            complement(28041..29144)
                     /locus_tag="RD451_001787"
     CDS             complement(28041..29144)
                     /locus_tag="RD451_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HDT7567046.1"
                     /translation="MNNVKINELRQWMAQHQVELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVDRFDAISDILTGTDSYTDLTSIIQRLQLIKTVEEKDKLIEAGKWADVAF
                     EIGFKTVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGSTKVSP
                     NELVLFDLGVIWNGYCSDATRTVAYQKPTEFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLE"
     gene            29354..30355
                     /gene="ccpA"
                     /locus_tag="RD451_001788"
     CDS             29354..30355
                     /gene="ccpA"
                     /locus_tag="RD451_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HDT7567047.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            30710..31105
                     /locus_tag="RD451_001789"
     CDS             30710..31105
                     /locus_tag="RD451_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567048.1"
                     /translation="MPKKRRKTIVIILTILTIGIGGKFYMDKREMQRQKDLLAVEKQS
                     VKVLKNTFADIKEVKIEKSARNEMTGSYRIVILMTNKQDQSIYFSYSFWKERNEIGSY
                     GIVDEKKQKEGNTLNKVKVTYSNGNEESI"
     gene            31105..31356
                     /locus_tag="RD451_001790"
     CDS             31105..31356
                     /locus_tag="RD451_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567049.1"
                     /translation="MITDKQYSELSDAVYWLDPKHRDYVPEMQENLSFKINGTMYKIL
                     KIKNSFDGMQAMAVAPIVHSKLEKNFKNKKIPANFRVLK"
     gene            31399..31794
                     /locus_tag="RD451_001791"
     CDS             31399..31794
                     /locus_tag="RD451_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567050.1"
                     /translation="MSRKIRKLSLAILLIVILGIGGKVYMDKREAQRQKDLLAVEKQS
                     VKVLKNTFADIREVKVEEFKKNPVTGSYGALVTMTNNEGKSVYFDYSFWKERNELGGF
                     GIENRAVQKTGVTIKRVKVIFSNGQEELV"
     gene            31791..33047
                     /locus_tag="RD451_001792"
     CDS             31791..33047
                     /locus_tag="RD451_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipase"
                     /protein_id="HDT7567051.1"
                     /translation="MTINDKHYNDISEKVYWLDPKYPRYNEGYKKNSVKEFAGMEFQI
                     LQIKDSLDGMQAMSVAPIKNGKVDLSQVVIAFAGTNLSDWKDLETDARSIMNLYGNRP
                     GASFSEKATTNKILSVSGLKTAGQINSAIAFANEVKKEYGEAAISTTGHSLGGFLALY
                     VAAEKQWKNVGFNGPDPYDLLSPEAKKWVEENPGMLTNYRNHADFIGNFGGNGTGAEV
                     RISMETAFLNLLASHSLTSWKFDENGKLIIPENENNVKARKQQKENQATQLFSYQLQE
                     LNNIRKKLRLSGGRLTVNEQIYLDDTQARLVVEKLSAKMKSAMEEVIRINQRGIFELE
                     KKWQEGLRQARVVAPSLTEQEIIEALASVGATKENLVDSAKEVYLLRINKARRMGEAF
                     DTLAKEIQDKINEIVARDRELAQQFN"
     gene            33059..33382
                     /locus_tag="RD451_001793"
     CDS             33059..33382
                     /locus_tag="RD451_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567052.1"
                     /translation="MKLEELERDYRSERRQLEAQEDELIYFKNQGLRLMEQEEQRLHH
                     VLKNLALDNEPLFQARRSYSNYQEHYQQALQVERRKLYQQQDELERSYRQKIRQITME
                     KSSYE"
     gene            33375..33641
                     /locus_tag="RD451_001794"
     CDS             33375..33641
                     /locus_tag="RD451_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567053.1"
                     /translation="MNEFLMQLLKELEKNLHRSNVRSVGMGISQQIWAEKRLTDQNYQ
                     MTAEEAAQEFSNRHVHLKGSVKGQFAEKLTELFQRQEKKLKQFR"
BASE COUNT        11283 a         5790 c         7245 g         9354 t
ORIGIN      
        1 gttagttcga gagctctttt ttttgctttg ctaccttgtt ccttgaagat tctgctgaat
       61 taagatagag ttaagttaac tacaagaatt ggagggatcc acatgaaatg gaaagaaaaa
      121 gtagacgaag cagctgaaaa gttatatgat ttggtcaaat cagaaaaata caatattgaa
      181 gtgaatattc cgaaaaaagg cggaaaagcg gtccaggtaa aatcaaaacg cccaacgaat
      241 catacaaaaa aatggatggc taaaaaccgc taataataac aaaagatcca taagtcggca
      301 ttttcatcga ttttagggtc ttttgttatt ttctaggttg aacatatcta aaaaattgtt
      361 tctgacaata ggagtaggga gaacgatgtg tgtctaaatc ctctgttgat ggatagaaac
      421 ctttatcttt ttcagttgtg aatcaggtat ataccagtta taatagaaga aacgaaagga
      481 cgggtgtacg ttatgtcgaa tcaattacct gtatatatac agattcatga ccaattaaaa
      541 aatgaaatcg aacagggtat atggaaagtc ggagaccgtc ttccttcaga aagagaatta
      601 gcagtgaaat tcaatgtcag ccgtatgacg ttgagacaag caattcaaaa cttggcagat
      661 gaaggaatct tagaaagaaa gatcggttcg ggtacgtatg ttgcgcgaga aaaagtacaa
      721 gaaaaaatgt ctggtgcaac aagttttaca gaaattatgg aatcacaaaa tcgagtaccg
      781 tctagtcgga caatctctta tttcttgact tcgccaagct caagtgaaat ggaaaaacta
      841 aacttgagta aagatgacac gatcttgcga atggaacgta ttcgtttcgc agatgatgtc
      901 cctatttgtt ttgaagttgc cagtgttcca caaaagctga tcgatggcta cagcaaagca
      961 gagattactg aatcgttgta tcgcacgcta gaagaaaaag gcgggaaaaa gatcggtcca
     1021 gcgaatcaaa cgattactgc tgtgttggct tctgagaaaa ttgctgacta tttagaggta
     1081 aaacgaggag atgcagttct tcgtttgcgc cagatttctt attttgaaga cggtacgccg
     1141 tttgagtatg tgcgtacgca atacgtagga aatcgttttg agttttattt ggaaaaataa
     1201 aaaacaggtg atccctgatt ccttattaga aataaaagag aatcagaatc acctgttttt
     1261 atatatgatc agttatcagt tgctcgtgat aagaaacaga accctcttca aattggactt
     1321 gtccgttcag cagctcaatg atggattctt taaagtggtc agcacttttt tcatctacag
     1381 cacagatgac gctaacttga tcagtatatt ggatttcttt tataaaaaaa tgttggagtt
     1441 caagataatt ctgtaatttt cctagttgcg gatacgtgat catcacagag atctcctgtt
     1501 gcaaggtacc ttctacgatt ccaatgtcag acaatgcttg agagaccgca tgagtgtatg
     1561 ctcgtattaa tccgcctgtg ccgagtttcg ttcctccaaa atatcgagtg actactgcag
     1621 ctacattgat cagttgattt tttttgagga cttccaacat cggtacgccc gccgttccac
     1681 ttggttctcc atcatcgctg cttcgctgga tttcattttt ttctccaatg atgaaggcgc
     1741 tgcagttatg gttcgctttc caatgttctt tttttatttc ttgaatgaaa ctttttgctt
     1801 ggtcctctga ttctattcgt ctaagagaac agataaagcg tgattttttg atctcaatct
     1861 cactttgtcc attttctttt attgtacgat agcgctcgat catcttgtca cctctttttt
     1921 tcattttctt tattcagtat aaataaagtt ctaggttgtt tcaacactgt aacggttgcg
     1981 caattgctgt agtatgcgat aataaagaca aaggcaggtg gatctgggga tgcaggaacg
     2041 aatgaaaaag tacgatgcaa ttacgcatta tttgaagaac aatggcggct ctcaagtaac
     2101 gttgaccttt acccaatttg acgaactgct gtttcccagt aacggacttc ccaaaacagc
     2161 aagggaaagt acagattggt gggcaaatga ttataaacac cctgaaaaag gtgcctatgg
     2221 ctggataaat gcaggctatg aagtagttgt catcaatttg gacaaagaat atgtcgtgtt
     2281 caataaatta gtgaaatcta gttggctatt tgattaaata aaccgcgttt agaaaacgtt
     2341 gacaaatttc tttcttttta tataatagag taacagacgc gaagaaaacg tttgcatagt
     2401 ttgttttaaa aaggagagaa aagtatggct aaaaaaacaa tcatgcttgt atgttcggct
     2461 ggtatgagca caagtttact agtaacaaaa atgcaaaaag ctgctgaagc aaaaggaatc
     2521 gactcggata ttttcgctgt gtccgcttct gacgcagata acaaccttgc aaataaagac
     2581 gtggatgtgt tgttattagg cccacaagtt cgctttatga aagctgattt tgagaaacgt
     2641 ctggaaccaa aaggcattcc tttagatgtc atcaatatgg ctgattatgg tatgatgaat
     2701 ggcgaaaaag tgttagatca agcaatcacg ctcataggtg aataaataga acagtataac
     2761 tatcgaacaa gcgatccaaa aaatagatcg cttgtttttt cgtatatttt tttagggcga
     2821 agaatatgaa tcatttttgg ggtagaaggc ttctgacgag agatattgaa gcaatagact
     2881 gtgaggaggt aaatttacca aattatgaga agatcgcagc agtggaacgt ttgggcaact
     2941 ggattctttg tcatcgctgt ggaatgagga cgtccgtcat tgatggacag cttgcagatt
     3001 acggttattt ttgtacacat tgtctatatt tagggcgatg cgacactcaa caagatttat
     3061 atttgtttga tcagcctgaa gcaaaacctc gagaagtcgt ctttttttgg acaggacagc
     3121 ttactgaaaa acaaacggaa atctcaaaga gaatactttg ccattcagaa aaaagacatc
     3181 atcttatttg ggctgtaaca ggtgcaggga aaacagagat gctttatcct attttagtgg
     3241 aaactttaaa agctggagga agagtagcga tttgtacacc gcgagtcgat gtttgtaatg
     3301 aattgttttt acgctatcgt tatgtttttc cagaagaaaa aatcacgttg ctccatggga
     3361 atacagcaac ggcttatacc tttacttctt ttgttatctg tacgattcat cagctatacc
     3421 gtttttatcg gtcctttgat ttaatagtga tcgatgagat cgatgcgttt ccttataacg
     3481 gggatgcagg attagctcat gctgtgcaaa cagcgattaa accagacgga cgattcatct
     3541 acttaagtgc cacacctgat aaaaagttac taaaggaaat caagcagacg tttgacatcc
     3601 acaaacttgc tttacgcttt catcggcgtt tgcttcctga acccgtcttg gttttcatga
     3661 ataattggcg acaaaaatgc aagaacaaga agaagataaa atctttggtg cggatcattc
     3721 atcaattaat taaagaaaac catatccttt tattttgtcc aagtatcacg atgatgcatc
     3781 gtttgaaagc cacacttcaa gaggctcttc cgagatatga gatcacagat gtttcttcaa
     3841 gagacaatca gcgggcggaa aaagtccaga aaatgcgaga agcaaaatat gatatactgt
     3901 taaccacgat gatccttgaa cgtggagtca catttgaaag aatatccgtt atcgttttag
     3961 gagcggatca tccggttttt actaaatctt ctttggtaca aatcgcagga agagccgatc
     4021 gtaaagggcc ttatacgaac agtcaagtat actttttcta tgaagaaaaa actgcagcta
     4081 ttcgaaaagc ttgtcaggaa atcaaagaaa tgaatgaaga agggaagaag atgctgtgag
     4141 gtgcagttgc tgcagtaaag atatcttcca aaatttaaca ttcagcgaga ttattggtgt
     4201 ttcgaaatac agattacctc agacttgttc agtttgtcgc gcacaatttc atttattgga
     4261 aacaagaggc tgttctggct gtcaaaaacc aatccatttc aatctagaga gtacgaaaaa
     4321 gaaagtaaag tctattcccg tttactgcag tgactgtcaa gaatggaaga agaaatatcc
     4381 gacctatgat tttcagcacc gtgccttttt tgtgtacgat gaaaatatga aggcctggct
     4441 caatcaatac aagtttatgg gagatatccg actagcaggc acctttgcat ataaatggac
     4501 gcagataaaa aaagaatacc cgacatacat ctattgtcca atacctttat ctgaaaaaag
     4561 gcgaacagaa agaggattca atcaagtaag cgagatgttg aaagcagcaa gaattccttt
     4621 tcagatgcta ctcaaaagag agaagcatct gctggctcaa gcaaaaaaca cgcgaaagga
     4681 aagattggag atgcctcaac cttttgaact tgcagtcacc ttttctaaga tacaaaataa
     4741 aaaaatattg attattgatg atgtctatac aacaggacag actcttttcc acgcagcaga
     4801 ttgtttgcag gtcgcacagc cgaaaatcat ccgaaccatt tctttggcga gatgaattag
     4861 atgtggaaat ttgatagcga tttaatttgc aaataaccta gagttcgata taatagaatt
     4921 aagaagaggg aaagagtggt ccttctcctt cttgattgtg gtagacgaaa ggggtaattt
     4981 ttatgtttag atataatgta cgcggcgaaa atatcgaagt aactgaagcg attcgcgact
     5041 acgttgagaa aaaagtaggc aaactagaac gctatttcag tgacgcaccc gatgcaacgg
     5101 cgcatgtgaa cttaaaagtt tatacagaaa aaacagcaaa agtggaagta acgatcccat
     5161 taccttatct tgtattacgt gccgaagaaa cttctccaga tttatacgca agtatcgatt
     5221 tggttgttga taaattggaa cgccaaatcc gcaaattcaa aacaaaaatt aatcgtaaat
     5281 cccgtgaaac gggcatgaat actgcagatg ctgctgcttt attcaatgaa gaggacgaaa
     5341 acgaaaatga ttctgaatta gatatcgtac gtacgaaacg cctttcattg aaaccaatgg
     5401 atagtgaaga agcagtctta caaatgaaca tgctgggaca taacttcttt atttttgaag
     5461 atgcagaaac aaatggtaca agtatcgttt accgccgtaa agatggaaaa tacggactga
     5521 ttgaaacaga ctgatcagcc ttacttaaat aacaacgaaa acttgcagca gctactgaca
     5581 gctgccgcaa gtttttttga gtttcctcct cttttagatg aaatatgaat aaattatgaa
     5641 gttcttactt taatacgctt aagatatttc aattatctat aactaatgat aaaatgaaaa
     5701 gtaaagtcta catagtctgg ataatacaca gaaggaaaag gagattacac aacgcatggc
     5761 caatttgatt cgttcactta tcgaaaacga taagaaagaa ctaaaacgtt tagatagcat
     5821 tgcaaaaaaa gttgaagcat acgctgacca aatggcagca ttaactgatg aacaattaca
     5881 ggcaaaaact gctgaattca agggcagata ccaaaaagga gaaacattag atcaattact
     5941 tccggaagct tttgcagtcg tccgagaagc agcaaaacgt gtattggggt tatatccata
     6001 ccacgtacaa ttgatgggtg gaatcgtgct tcacgatgga aatatccctg aaatgcgtac
     6061 tggtgaaggt aaaaccttga ccgcaacgat gccagtatat ctaaatgctc tgactggcga
     6121 aggggtacac gtagttaccg tcaatgaata tttagcaacc cgtgactcga cggaaatggg
     6181 cgaactttat aatttcttag gattaacagt ggggttgaat atcaactcaa aatcttcgga
     6241 tgaaaaacgc gaggcttata attgtgatat cacttatagt acgaataatg aattaggatt
     6301 tgactacttg agagacaata tggtcgttta ccgccatcaa atggtacaac gtccgctgaa
     6361 ttatgccatt gtcgatgaag ttgactcaat cttgattgat gaagcgagaa cgccgctgat
     6421 catttcaggg caagcagaaa aatccacagc tttatataca agagcagaca acttcgtgaa
     6481 acgtttgaaa gaagaagaag attataaaat cgatgtacaa tcaaaaacaa tcagtttaac
     6541 cgaagcaggg atcgaaaaag cagaagaaac attcggtttg gataacttat acgacattga
     6601 aaatactgca ttgacccatc acttggatca agcattgaga gccaactata tcatgctttt
     6661 agatatcgat tatgttgtcc aagacggaaa agtactgatt gttgaccagt tcactggtcg
     6721 gatcatggat ggacgccgtt attcagatgg acttcaccaa gcaatcgaag ctaaagaagg
     6781 cgtagagatc gaagacgaaa cgaaaaccat ggcgacgatc actttccaga actatttccg
     6841 tatgtacaag aaacttgcgg gaatgactgg tacagctaaa acagaagaag aagaattcag
     6901 agaaatttat aacatccaag tataccagat tccgacaaat cgtccggtta tccgtgatga
     6961 tcgtccagat ttactttacc caacattaca aagcaagttc cacgctgtcg tgcaagatat
     7021 caaagatcgc taccgcaaag gtcaacctgt gttagtcgga actgttgcgg ttgaaacatc
     7081 tgagttatta tcagatatgc tgaatcaaga acgtattcct catgaagtgc tgaatgcgaa
     7141 aaatcacttt aaagaagcag agatcatcat gaatgctggt caaaaaggtg ctgtgacgat
     7201 tgctaccaac atggctggtc ggggaacaga tatcaagtta ggacttgggg taagagaact
     7261 tggtggtcta gcagttatcg ggacagaacg acatgaatct cgtcgtatcg ataaccagct
     7321 tcgaggacgt gcaggacgtc aaggagaccc tggtatgtca caattctact tgtcattgga
     7381 agatgatttg atgaaacgat tcggttcaga acgaatcaaa gctttcttag atcggatgaa
     7441 gatcggtgag gaagatgctg ttatccaaag caagatgctg acgaaacaag tagaatctgc
     7501 acaaaaacgt gtagaaggaa ataactatga cacacgtaaa aacgtcttac aatacgatga
     7561 tgtgatgcgt gaacaacgtg aagtaatcta taaacagcga caagaagtaa tcatggaaga
     7621 aaaaagctta tccaagccac taatgaacat ggtcaaacgg acaatcagtc gtgtagtaga
     7681 tgcgcataca caattagaga aagaaaattg gaatttggaa agtatcatcg attttgccgg
     7741 cagtactctt gtccatgaag atagtattac tcttgcagat atcgaaggaa aaacatctca
     7801 ggagatcaaa gagtatctaa acgaacgagc acaagaagta tttaatacca aagcggctca
     7861 actaaatggt ccagagcaac tgttggaatt tgaaaaagtc gtgatcttgc gtgttgtgga
     7921 ctctaaatgg acagaccata ttgatgcaat ggatcaatta cgtcagtcaa tcggcttacg
     7981 tgcttatgga cagaacaatc cattagtcga atatcaaaca gaaggctata agatgtttga
     8041 agatatggta ggcgccatcg agtatgaagt cactcgaatc tttatgaaag ctgagatccg
     8101 tcaaaacgta cagcgtgaac aggtttctca aggaacagct tctcactcag aagacggaga
     8161 tgccaaagaa aatagtaata ctagcgcgaa aaaacagcca atccatgtga acaaggtcgg
     8221 aagaaatgat ccttgtcctt gtggaagcgg gaaaaaatat aagaactgtc atggaaaaaa
     8281 tgcaaactaa tttctgacag caggattggt gagacaaatt ctttttttaa gaattcgtct
     8341 caccttcttt ctgttatttg ctgattctgt tagactagat ataatgaaaa aagtatagtg
     8401 aaagaaggaa aaaacatgga aatatccgaa attcgaaatc tcctgacaga aatgcaggaa
     8461 aaggtcacaa gtttcaggag gtctctttga cttagatcag ctggaagaag acatcgcgga
     8521 agcagaagca aaaatggctg aacctggttt ttgggatgac agcgaagccg cacaaaaagt
     8581 gatcagcgaa aataacgcta ataaagaaac ctatgaccaa ttccattctc ttgccgaaga
     8641 actagaagaa atcgaattga tggtggagat gctgcaagaa gaacctgatg cagcaatgca
     8701 agaagaagca gaaacacgta tcaatgcatt agatgaaaaa atgaagacgt atgaattatc
     8761 tatgctgtta gacggacctt atgatcgaaa caatgcgatc gtcgaattgc atccaggggc
     8821 tggcggaacg gagtcccaag actggggcag catgctttta cgtatgtata cacgttgggc
     8881 agagcagcat ggctatcaag tagaaacact agattatcaa gcaggtgatg aagcagggat
     8941 caagagtgtg accctgctga ttaaaggaca taacgctttt ggttatctaa aatcagaaaa
     9001 aggtgttcat cgccttgtac ggatttcgcc ttttgactca gcgaaacgac gtcatacttc
     9061 tttttgttcg gtagatgtga tgccagagct tgatgaaacg atcgatatag aaatcaatcc
     9121 agatgatttg aaaatcgata cgtaccgagc aagtggtgca ggtggtcagc acatcaataa
     9181 aacagaatct gctgtacgga tcactcactt gcctacagga acagtagtag ctagtcaggc
     9241 acaacgctca caattgaaaa accgtgagca agcgatgggg atgttaaaag ctaagcttta
     9301 tcaattagaa gtggaaaaga aagaacaaga agcagctgca cttcgaggag aacaaaaaga
     9361 aatcggctgg ggttcacaga tccgttctta tgttttccat ccctattcta tggtaaaaga
     9421 ccatcggaca aacgtagaga caggaaatgt ccaagcagtt atggacggtg accttgattt
     9481 atttattgac ggctatttaa aaatgcatct acaataagaa ctcattgtta aattgaaata
     9541 aaattgtaag attttgcaag catgttgaaa cattgccatg ctataatagc taaagactga
     9601 aaaagatatg gagagaacgc catgattgaa atgaaggatg taatgaagaa gtactcaaat
     9661 ggtacgaccg ctatccgcaa tctctcgatt gtcatcgaac aaggagagtt tgtctatgtg
     9721 gttggtccgt ctggagccgg taaatctaca ttcatcaaat tgatgtatcg agaagaaaaa
     9781 gcttcaaaag gaactttgaa cgtcgcaggt catgatctaa tagcaatcaa aaaccgcgaa
     9841 gttccttatc tacgcagaga aatcggcgtg gtgttccaag actataaatt attaccaaga
     9901 aaaacagtat atgaaaatgt tgcgtacgct atgcaagtta tcggcagaaa acctcgagat
     9961 atcaaaaaac gagtaatgga agtgctggac cttgttggtt tgaaacacaa agttcgagtc
    10021 tttcctagcg aattatccgg tggggaacag caacgtgtct ctattgctcg ggcaatcgtg
    10081 aatacgccta aagtacttat cgcggatgaa ccgacaggaa atctggatcc agaaaactca
    10141 tgggaaatca tgaaattatt agatcggatc aatgcccaag gaactactgt cgtgatggct
    10201 acacataaca gtacgatcgt aaatacgatt cggcaccgag taattgctat cgaaaacggc
    10261 cgcattattc gagatcaagc ggaaggggaa tatggatacg atgattagaa cctttttccg
    10321 ccatttatta gaaagtatca agagtttgaa acgtaacggc tggatgacag ttgcttcagt
    10381 cagtgcggta acgatcacgt tgactttagt cggtgtattc atggcagtta tcatgaatgc
    10441 aactaaatta gctcaggata tagaaggaaa cgttgatgta tctgtattcg tagatatcgg
    10501 tacaaaagac gaagagatga aaaagctaga aaaagaattg aatgacttag atcatgttaa
    10561 aaaagttgaa ttttcaagca aagaacagga attgaaaaaa atccaaaacg aaatgggtga
    10621 ttcctggaaa ttgtttgaag gtgacaataa cccgttatat gatgtgtatg tagtaagtgc
    10681 tactgatcct tcttatacaa aacaagtagc agaagaagca gcagatttga agaatgtttc
    10741 tcgttctgat tacggtggag cttcctcaga tcggattttc caaatcgctg gtgcagttcg
    10801 gacatgggga ttagttgcag cggcattgct gctgttcgta gcgatgtttc tcatttcgaa
    10861 cacgattcgg atcacgattt tgtctagaca gcgtgaaatt caaatcatgc gtttagtcgg
    10921 tgcaaaaaat ggatatattc gctggccgtt tttccttgaa ggtggctgga tcggtctgat
    10981 cggtgcgatt cttccgattt tgatcatcac atttggttat gcatggtttt tccaattgat
    11041 caatccatca ttattacgtt cccattattc attgattcgt ccacaaaata tcgtttggaa
    11101 aatcaatctt ttaatggtcg gcattggtgt gatcattggt tcacttggct cgatcatttc
    11161 tatgagacgt tttttgaaat tctaatacca caatataaat aaaatgagaa agttggacag
    11221 tttcgttcca gctttctttt tttattggct aggagaatag aaggaagcgg cttttttccc
    11281 tttactttaa aaaacaactt gggtattctt aagttggtag aagaagaggt gaagccgtga
    11341 aaattatcgt tgacaatttt tttacgatcc ttttgattat gaatattttg ctttccttta
    11401 tcatcgtttt tcgagaaaga aaggaaactg ctcaaacatg ggcatggctg ctcgttttga
    11461 tgttcattcc agttgtagga tttattttat atattttttt aggaagaggg atttccaaag
    11521 agaaaatctt tgatttgaag atccaaggga aaatcggtaa gaacctggaa attgaagaag
    11581 acaaacaggc attgatgcga gggctttatc ctcatccgcc tactggacaa gtagatgtga
    11641 aacaattgat ctatatgctc acggtatttg aaagtacgct ctatacgact aaaaatgaaa
    11701 tcactttatt tacagatggt cgtgaaaaat tcgatgcgct gattgaagat atcaagcagg
    11761 cagaagacca tatccacttc cagtattata tttatcgcag tgatgcatta ggtgaagaag
    11821 ttcgagatgc attgacagag gcggcaagac gaggggtaaa agtcagagtc cttcttgatg
    11881 catggggttc cacacaagtt tcttccagct tttttcagaa tttgaaaaaa gcaggcggag
    11941 aagtcgcatt tttctttcct ctatttgttc cgtatattaa tcctcggatc aattatcgca
    12001 atcatcgtaa aatcgtagtt attgatggga aaatcggata tacaggtggg ttcaatgttg
    12061 gaaatgaata tctaggattg gtaaagaaat ttggttattg gcgagacaat catttgcgta
    12121 tttacggaga agcggtgtat accttgcaaa accgtttttt gatggactgg aattctcagc
    12181 atacaaaaga agtaggctat tctcccaaat ttttcccgtc cattcacact actggtgata
    12241 tagctgttca aatcgtgaca agcggaccag ataccgaaca tgaacaaatc aaaatgactt
    12301 atttgaaaat gatttcgtta gccaaacggg agatattgat ccaaacgcct tattacatac
    12361 cggatggatc gattcatgaa gcactgaagt tggctcttct ttcaggcgta aaagttcata
    12421 tccaaatacc taacaaacca gatcatcttc tcgtttactg ggcaacgtat tctttcgctg
    12481 cagagctgat cgagtatgga gcaaggatcg aaacatatga gaatggattt attcatgcaa
    12541 agacgatgat tatcgatggt ggcattgttt cagttggctc agcaaatatc gatgttcgtt
    12601 catttcgctt ggactttgag gtcaatacac tggtttatga tgaacgaatg gcttcacgtg
    12661 taagaaaagc tttttttgaa gactcgaaaa tttctacgca tctcacaaaa gaaatgtatg
    12721 aaaaccgagg aataatcatc aagatgaaag aaggattagc aagattgatt tcgccgctcc
    12781 tttaaaacat aaaaaggaca tgagaaccat caacagatgg agatctcgtg tccttttcta
    12841 acggggccat ttctgagagt acgtcagaaa tggagaaagc gtctcgcatg agcgaaatta
    12901 actttggggt atctcttgtt ttttggggaa agcaagaaat aagctaatat atgctattaa
    12961 aagagacaca tttcaaagcc agtatagcat agaaactttt aatgagatag ttttttttac
    13021 aattatgaga atttattttg ttatttaatg attttgattc gttttcatca agtaatgaaa
    13081 atgataaaat aaacatactt taggattaaa ggagatttct aatgaaaaaa cttaaattat
    13141 tcttaccaat aataggatta gccattcttt tatcaggctg ttcaaagtgg attgatcgag
    13201 gagaatccat tacggctgtt ggctcttctg ctttacagcc tttagtagaa acagttgctg
    13261 aaacttacca gacagaaaat cctggaaaat tcatcaatgt acaagggggc ggaagcggaa
    13321 ctggtttgtc tcaagtacag tcaggagcag tcgacatcgg aaactctgat ttgtttgcgg
    13381 aagaaaaatc ggggatcgat gcctcagcat tagtcgatca tcgagtagca gttgttggga
    13441 tcactcctat tgtgaacaag gatattggcg taaaagacat cagtatggaa aacctgaaaa
    13501 aactatttac aggcgagatc aaaaactgga gtgaagtcgg tggaaaagat cagccagtag
    13561 ttatattgaa ccgcgcttca ggaagcggaa cccgtagcac gtttgaaaaa tgggtattgg
    13621 acggagaaac agctgttcag gcacaagaac aagattcaag cggaatggtg cgccagatcg
    13681 ttgccgacac acccggtgca atcagctatg ttgctttttc ttatgtttcc gatgatgtag
    13741 atacgttgaa tgttaacggt gtagaaccga cagatgaaaa tgtgacaacg aacaaatgga
    13801 cgatttgggc atatgagcat atgtacacaa gagatcatcc aaaaaaactg acaaaagaat
    13861 ttttagacta tatcttatct gatgaagtac aagataacat cgttggagaa ctaggttata
    13921 tccctgtttc tcatatgaaa gtcgaacgtg attggcaagg aaatatcgtt aaagagtaat
    13981 ctttacacaa aatttacaaa cttagctaaa cttttacatg ttattaaaac caaattgatg
    14041 ttcaatttgt acactgagtg agtatgttaa acctgattaa gggggagtca tctgtggaag
    14101 atgtgaaaaa agtattatta acaaaatcaa aacgttcaaa aatggaacag cgtggaaaat
    14161 tcatcagttt tttatgtatc gcgctgatcg tgttggttgt attatctatt ttttattttg
    14221 tagctagtaa aggattggcc acctttttta ctgataagat caatgtattt gattttctgt
    14281 ttggtacaga ttggaatcca agccaaatcg gagcaaatgg gaaaccaatg gtaggggcat
    14341 tgcctatgat cacaggttcg tttattgtga cctttttatc tgctatcgtt gccacgccat
    14401 ttgccattgg tgcagcagta ttcatgacgg agatctctcc taaaaacgga acgaagatct
    14461 tacagccggt catcgagctg cttgtaggta ttccttctgt cgtttatggt tttatcggtt
    14521 tatcagttat cgtgcctttt gtcagaagta tttttggcgg gacagggttt ggtatcttag
    14581 ctggtacatt tgtgttgttc gttatgatct tgccgactgt cacaacgatg actgttgatg
    14641 cattaaaggc agtaccacgg cactatcggg aagcttcatt agcgcttggt gccacaagat
    14701 ggcaaacaat ctacaaagtc gtgctacgag cagccgtgcc cgggatttta acagcagtcg
    14761 tttttggtat ggctcgtgcg tttggtgaag ccttagctat ccaaatggtc atcggtaatg
    14821 cagcattgat gccaacagga cttactactc ctgcttctac attgacgtcc atcttaacaa
    14881 tgggaatcgg aaatacaatc atgggaacag ttgaaaataa tgtgttatgg tcattagcgc
    14941 tgatcttgct attgatgtca ttattcttta atatcgtgat ccgtatgatt gggaagaaag
    15001 gagagctgaa ataatgaacg caaaacgctc agataaaatt gctacaggtg ttttatatat
    15061 agtttcgggg atcatcgtat tgattttagc agctttacta ctttatatct tagttcgggg
    15121 aataccgcac atttcatggt ccttcttgac cgaaccttcc aaagcctacc aagaaggtgg
    15181 tggaatcggg atccagctat ttaactcgat ttatttgctt ttgatcacga tgatcatcag
    15241 ttttcctatt tctttaggtg cgggtatcta tctttcagaa tatgctggaa aaaactggct
    15301 aacagatgtg attcgcacgt cgattgaaat cttgagctcg ttgccttctg tcgttgtcgg
    15361 tttattcggt ttcttggttt tcgttattca attccagtat ggtttctcga ttatttctgg
    15421 tgcattggct ttgactgtat tcaacttgcc tcttttgact agaacagttg aggagtcttt
    15481 acaagcggtc cattacacac aacgagaagc aggattggcc ttaggtttgt cacgctggga
    15541 aacagtgatg aaagtggtgg ttccagaagc gacaccaggg attttgactg gtgtgatcct
    15601 aagttctgga agaatttttg gtgaagcagc tgcattgatc tatacggctg gacaaagtgc
    15661 acctgcgtta gattttacga actggaatcc attaagtgtt tcaagcccga tcagcatttt
    15721 ccgtcaagct gaaacattag ctgtccatat ttggaagatc aatacagaag gcacgatgcc
    15781 tgatggtgtt tctgtttcgg ctggcgcttc tgccgtgttg atcattgctg ttttactgtt
    15841 caacttcggc gctcgtgcga ttggcaaacg attataccga aaaatgactt cagcctaagg
    15901 agaagaagca aaatgaaaaa atataactgg aatgaaacaa atgtcatcac catgccaaaa
    15961 gagaaagaag tagcactata tacggatgat atacatgtct ggtatggcga caatgaagca
    16021 atcaaaggag tggatctgga atttgaaaaa aataagatca ctgcactgat tggtccttcc
    16081 ggctgcggaa aatctacgta tcttcgttcg ttgaatcgaa tgaatgatgg gatcgctaat
    16141 acgaaaatca ctgggaaaat catgtatcaa ggcgtagata ttaatgcgcc tcaagtggat
    16201 gtttatgaga tgcgcaaacg gattggcatg gtttttcaac gtcctaatcc gttcagcaag
    16261 tcgatttatg acaatattac atttgctttg aaacagcacg gcgaaaaaaa caaaaagaaa
    16321 ttagatgaaa tcgttgaaac aagcttgaaa caagctgcct tgtgggacca agtaaaagac
    16381 agcttggaca aaagtgcctt ggctttatct ggcgggcaac agcaacgttt atgcattgct
    16441 cgtgcgatcg cgatgaaacc tgatatcttg ctgctagacg agccggcaag tgctttggac
    16501 cctatttcga caggaacggt tgaagaaaca cttgtaaact tgaaagaaga ctatacgatc
    16561 atcatcgtga cgcataacat gcaacaagca gctcgtatca gcgactatac tgcctttttc
    16621 tatctaggaa aagtaatgga atatgacaaa actaacaaga tatttaccag accaaaaatt
    16681 caggcaaccg aagattatgt gtccggtcat tttggttaag acggaggcct caacatgaca
    16741 aaagaaatta tttcatctaa agatcttcat ctgtattatg gaaagaaaga agcactaaaa
    16801 gggatcgatc taagtttcaa tcaaggggaa atcactgcga tgatcggtcc ttctggttgc
    16861 ggaaaatcca cttatctgcg ttctttgaac cggatgaatg acctgattcc gaatgtaacg
    16921 atcaccggaa gtgttttata taaagacaaa gacatctatg gtccaaaaac agatgttgtt
    16981 gaactaagaa aagaaatcgg catggtattc cagcagccaa acccatttcc tttttctatc
    17041 tatgaaaatg tcatctatgg attgaaatta aaaggggaaa aagataaaaa agtccttgat
    17101 caagtagttg aagaaagcct gaaggcagcg tctgtttggg atgatgtgaa agacaaattg
    17161 cataaaagtg ctttatcttt atccggcggg cagcagcagc gtgtatgtat cgcacgtgtt
    17221 ttggcagtta atccggaaat catcttattg gatgaaccaa caagtgcgct tgatcctgtt
    17281 tctactggga aaatcgaaag tatgctgtta gaattaagag agcggtatac gatgatcatc
    17341 gtgacccata atatgtctca agcttcacgt atttcagata agacggcatt ctttttagat
    17401 ggtcacttga tcgaatacaa cgatacgaag aagatattca tgaatccaga aaaacaagag
    17461 acagaagatt atatttcagg tcgatttgga taaggaggaa acggaatgct acgtacacaa
    17521 tttgaagaag aattgctgaa tctccataat cagttctacg aaatggggat gatggtgagc
    17581 agcgccgtgc acaagtcagt tcgtgcatac atcaaacacg ataaaatctt agcccaagaa
    17641 gttatcgaaa acgatataaa tatcaataac atggaaacac gcttggagaa gaaaagtttt
    17701 gaaatgatcg cattgcaaca gccagttaca actgatttgc gtatgatcat tacggtcatg
    17761 aaagctagct cggatttaga acgtatggcc gatcatgcgg tgtctgttgc taaatccacg
    17821 attcgcgtaa aagggcagac gagaataccg gaaatcgaaa aagagatctc cgatatgtcc
    17881 gattatgtga aaaaaatggt ggacaacgtc ctagttgctt atgtcaaaac agacgaaaaa
    17941 gacgcacgta cgatcgccaa tatggatcaa agagtcaatg actatttcaa tcgaatctat
    18001 aatgcaacaa tcaaaaatat gcaggaaaat cctgagacag tcatcagtgg aacagactac
    18061 ttgaatgttg ccagttatct agaacggatc ggagactatg tgacaaacat ctgtgaatgg
    18121 atcgtctact tggctacagg gaaaatcact gagttaaata cgaaccacaa tgagattttc
    18181 taaactgaag ctgtgattat gccgtttgtt tatgaaaaga ggttgtgaaa aagctgttct
    18241 acatcaagta ataagaacag tcaaacaaaa aatagctcct catatttttc gtttggctgg
    18301 acttattacc gcagatgcaa gcttttgaac accgtttatt cgggaaaggg tttgtgacaa
    18361 aacatgtcac aaaccctttt catcatttca tagaaaggat aaagaatgca aaaaaaaatt
    18421 agcatcatca ctatattttt tatttgtgtg cttacttcat gggttattca gcatcaagcc
    18481 gctttatatg aagtacctgt catcgagata gaaaaagtac gaataaaaga ggatcatcaa
    18541 ttgattacag gaaaactgat gaactcggat caaaaaggag aatcgattta tttatcggtt
    18601 ccttatcaaa aaaatcaaat agaaacagca aatataaaag cgagacaaat gtatctagtc
    18661 caaatgcatg gagatgaatg gcagctagta gcaaaaaaaa atgatggctg gcttttcttc
    18721 ttcacaagta tcttcattgg cgccatgttg cttattggcg gaaaacaggg tctatttgct
    18781 ttaggaagtc tcatcatcaa tatcgtttta cttttacttt tgttgctcat ctttactaaa
    18841 acagaaggga tttctctatt aaataaatct atcctgttcg tcgttatagg gatgattatt
    18901 agcatattgg ctttagatgg atggaataga agcagtataa tcaaaatttc agctgcagtt
    18961 acgagtgttt ttttagcatt ttttatttgt cttttgacaa tgaatcattg gaaagaccaa
    19021 ggactgcgct atgaggaact gaattatctg acacgaccgt atcgttctgt ttttctttct
    19081 agcgtactga ttggaacagc tggaggaaca ctcgataccg ttatcacagt cattgcgaca
    19141 ttagaagaat tgactaagcg acaaccagaa ataacagcga aacagttatg gctttcagga
    19201 aggcaagtgg gtcgagatgt gattggctcg atgaccaata tccttttgtt cgtctatatc
    19261 agtgggtcag ttccatcgct tcttttatat ttaggaaatc aatggtcttt caaagaaacg
    19321 atagaacagc atttatcatt ggaattttta cgcgtcattg ctggcagctt aggaatagta
    19381 ttatcgatcc ccatctcggt cctctttttt ctgactgtaa ggaggctgaa acgatgaatg
    19441 tacttattat acttgttggg attttagcaa tcagcgtgct acttattggc ggtacgcaag
    19501 gtatgtatat tcttttaggc ttattcatca atttagggat ctttttcctg ttgttattcg
    19561 gttatcatca gaagtggccg atactggcat tgtcggtcat aggattttta ttgattgctg
    19621 tggttatctt attttttatc aacggttata atctaaaaat gcgtgcagct tttgtgagta
    19681 tactgatctt tttattttgt ttcctactat tgcttcctat cactgatttt ttagcgatcc
    19741 aaggttttac atcggtagaa ctagaagaat tatctggctt agataagact ttagcgattg
    19801 attttagatt acttacgaga tcgttgcttc tgattagtct tagtggtgct gttttagatg
    19861 cgagtgtagc aatttctagt gggacattcg aagtatatca ggcaaatccg caattatctt
    19921 tttaccaatt gcgccattct agtttcgcta ttgctaaaaa aatattggcg tcaacagtaa
    19981 tgacacttct ttttgcattc atgggaagtt ctttagcgtt gatcctctgg tttattgatt
    20041 tagacattcc ttttcagcaa gtgatcaatg aaaaatcatt tgttctagaa tatacgatgg
    20101 ctattcttac cacattgtcc gcactaattg ttcttccttt aacctgcgtg actacagcat
    20161 atctctttac aaaaaagaaa gaacaactca agatggagta aaagttacaa cttaagtcct
    20221 atgacatttt tactgaatca gtgcataata tggatgtaag gaaaagcttg caaacaattt
    20281 tgcttaagga ggcaatttcc atgaaagaaa gagaacgtat tttagattta gtgaaaaaag
    20341 gaatcctttc gactgaagaa ggcttagatt tattagaaag catggcaact gaaaaagacg
    20401 aaaagcaaat caaaaaagaa gcagacaagg taactgctag tcataaagaa aaagataagg
    20461 caagtcaatt gatcgataaa cttgaaaacg gcgaagaaga aatttctgag ccagttgatc
    20521 caaaggaaag agaaagacaa gatcaagaaa acttagaaaa gatcttagat gaactagcaa
    20581 ctgaagcgaa taaaacttcg gcgcgtctag atgaagtaaa tgctcaattc gctgacaata
    20641 aggcagcacg caatgagaaa caggaagcat tgatgcagct gaatacaaaa gaagaattag
    20701 gcgagttgac agaagaagaa ttagcacagc gtcaggcgtt agaggcagaa atcaaagagt
    20761 tagaagctag tggcgataca ctgttagaag aacaattgaa attagaagca gaattaaaag
    20821 atatccgtaa gaatcaatgg tctgagaaaa aagaaacgtt tactgataag tttgaattgc
    20881 cagatgattg gaaagatcaa gcaacagata cactgaatca agtaggcgaa aaaatgtcag
    20941 aagctggatc acagttaggc aaattcttga agaaaacatt ccaaactgtt tcagaaacag
    21001 tgaatgacaa catggaatgg aaagatgtca gcttacgtgt ccctgggatt gcgacaacga
    21061 aatttgagca tgaattttac tatgaagctc ctgcagcaag tatccttgat atcaaggcag
    21121 caaacggaaa cgtgacgtta aaaacgtggg acagcaacga tgtgaaagtt gaagctaaga
    21181 tcaaacttta cggaaaaatg ggtgctgaac catttgaagc attctctgaa cggagccaga
    21241 ttgaggttaa tgaagatcat atctccttcc aaattccaaa taaacgtgtg cgtgcagacc
    21301 ttgttttcta cttacctaaa cgagtatacg accacgcagc tattaaactt ctaaatggca
    21361 acatcatgat tgaaacattg gaagctaaag atatttatac aaaatctacg aatggtaaca
    21421 tcatcgtgga ccaattaact gcaacgatgc tggaagtaga aggtgtaaac ggcaatatcg
    21481 atattcgaaa cgggaacatc ttagattcta ttatcgaaac agtaaatggt acagtgacat
    21541 ttggtgcgac agcagaaaat ctttctgtgt ctttagtaaa tggtgatgta cgtcttacga
    21601 ttaaagaaga taatttgaaa aaagtagaag caagttcagt gaacggaaat gtcaaagtcg
    21661 ctttaccaga tggcatcggt ttggaaggac atgctaaaac aagtcttgga agtatcaata
    21721 gccgtctgtc caattacgaa gtagttcgtg agaaaaaaga acggacaaac caaatgttgc
    21781 aattccgtcg tgtttcagat gatgagatcg cgcaagtgca actttcaacg acaacaggaa
    21841 gtatctattt aaaagataca gataaataaa gaggttgtga aagagatgtt cagccttgag
    21901 caataagaag cgattttgta aaatagcttc ccctatttta caaaattgtg ccttattgcc
    21961 gatagtctat ctcttgaaca ccgtttacca agagattatg aacctgccaa ttatcgccga
    22021 gtcacaagga ataatttcag aaaaagctcg tcacgtttta tgaatatggt aatttgtgac
    22081 cgagaatttt gcagaaagac accgattaag aagaaggttg tcacaacgat tttcttcatt
    22141 taaaatagta gaacagaggt gagacatgat gaaaaaaaag ttgacaaaat ctaataaaaa
    22201 tgttgttttg acagggactt tagcaggaat aggagaatac atcgggattg atccgactgt
    22261 tatccgtgtg ctttatgtat tcctgagctt agttgctttt ggaagtccaa ttattttata
    22321 cattttatta gctttgatta tcccatctgc gcgttctgca cgaacaaact atggacataa
    22381 caatgcatat tatgaaaaaa acaattatcg tgaacaaact cgtgaacaaa caaaaaaacg
    22441 caaagaagcg gaaaaaatcg atgatgacga atggagtgac ttttaatgtc gtactttcaa
    22501 cgtattttag ttaatacgtt aacattcata tcattggctg ttctttttcc tgcgatggtc
    22561 catgtgagca gtatttggac ggccgttctt gccagcttcg tattgtctgt gttgaatatg
    22621 tttgtcaaac cgattttgac gatactgtcc ctgcccttta cattagtcac attgggattg
    22681 tttacgtttg ttatcaatgc agcgattctt aaaatgacct ccttttttgt gggagcagaa
    22741 cattttagtt tttcttcatt cggtgcagcg ttgttagtag ctatcttgat gtcgcttgtc
    22801 aatgtaattg tcagcgaaca taacagtaga aaataaaaga aagctgtgcc gaactatcgg
    22861 cgcagttttt ttatttagaa tcaggaatgc gttttctatt acattggtaa ttaaataaaa
    22921 acgttttttt taattggtag tacttttggc tagacaatga taaaatgata gagaacactc
    22981 taatagaaat gaggtagcat gaatgtcaga agttgtaaaa gttagccaat tagtgaaaaa
    23041 attatctttg gaaatcgtga caggcgacga gaaaagctta gaccgtgtca tcgtaactgg
    23101 ggacatctca cgcccaggac tagagttgac tggttatttt aattattatt cccataatcg
    23161 tttacagcta tttggcagta aagaaatcag ttttgcggaa cggatgatcc cagaagagcg
    23221 tttgatcatc atgagaagat tatgtagtga agatatgccc gcatttatta tttcaagagg
    23281 attaccagct ccagaagaaa tgatccaggc agcaaatgaa aatgggatag ctgtactgcg
    23341 ttctcccatc tcaacttctc gtttattagg agaattatcc agttatttag atggtcgcct
    23401 tgcccctcga acaagtgtcc acggtgtttt agtggatgtt tacggattag gtgtactgat
    23461 tcaaggtgac agtgggatag gaaaaagtga aacagcgttg gagttgatca aacgcggcca
    23521 tcgattgatc gcagacgatc gagtagatgt ttatcagcaa gatgaattaa cggtgatcgg
    23581 agaaccgcct aaaatcctgg aacatctgat tgaaatccga ggaatcggga tcattgatgt
    23641 aatgaatctt tttggtgcga gtgcggtacg tggctctatg caagtccagt tggctgttta
    23701 tctggaagca tgggcaaaag ataagaaata cgaccgtctg ggctctgaag acacgaccgt
    23761 tgaaatcgcg gaagtgggca ttccacaaat aaaaatccct gtcaaaacag gacgaaacgt
    23821 tgcaatcatc attgaagtag ccgcgatgaa tttccgtgca cgtacaatgg gctttgacgc
    23881 aacgaaaaca tttgaagaaa gattaagtcg cttgattgaa gaaaactcag gcaacgacta
    23941 gcaaggagtg acaatatgtt agcacaaatc aatcgagttg cttttgagct tgtagggatt
    24001 cctatctact ggtatgcatt gatcatcgta tcaggtatca ttatcgctat gtggcttagc
    24061 agcagagagg ctgttcgggt aggattaaaa gcagatgatg tgacagattt tatgttgtgg
    24121 ggattgccta tctccattat tggcgctcgc ttatattatg ttttatttga tcttccccag
    24181 tatatagctg atccaatcca aatattcaat atccgttcag gaggcttagc tatttatggc
    24241 ggactgattg caggcgcgat cacgctgtat ttttttacta aatatcattt tatttctttg
    24301 tggacttttt tagatatcgc tgcaccaagt gtattattag cacaggcaat cggtcgttgg
    24361 ggaaatttca tgaaccacga agcatatgga ccagacacga cgcgaagctt cttagaaagt
    24421 ctgcatttac cgcaattcat cattgataat atgtatatcg aagggatcta tcgtcaacca
    24481 acatttcttt atgaatcact ttggagtttg attggattta ttttgctttt gtttttacga
    24541 aagaaaccac accttttgaa aaaaggcgaa gtccttttat gttatctaat gtggtatagt
    24601 ttcgggcgtt tctttattga aggattacgt acagacagtc tttacttttt aggtgtgatc
    24661 cgtatttctc aattattatc tgctgtgtta tttgtcggta cattgattct atttatttgg
    24721 cgcagaaaaa aaggaaattt accggattat gaccgctcat taggaaaaaa tcaacaaatt
    24781 atctgatttt tagagcgtta aaaatgaaaa aaatttcagg agtggtaaaa tgaattatag
    24841 agtagcggtt ttaggaccag gctcttgggg tactgctttg gcacaagtcc tcgccgaaaa
    24901 cggacatgac gttcggattt ggggacatcg tgcttcacaa gtagaagaaa tcaacaccca
    24961 acacacgaat caacgttatt taccagatca ttatctaccc gattccatcc aagcattcac
    25021 caatatggaa gatgcagtaa aagacgcaga tgcggtgcta ttcgtcattc caacgaaagc
    25081 aatacgttct gttgcaaaag aactagtgcc taaattgaat acaaagccag tgatcatcca
    25141 tgcaagtaaa ggattagaac agggaacaca taaaaggatc tctgacatct tgttagagga
    25201 aatcccagca gaaaaaagaa aagctgttgt tgttctttct ggaccaagcc atgcagaaga
    25261 agtagcaaaa catgacatca ctacgatcac agctgcaagt acagatgcaa aagcagcaaa
    25321 atatgtacaa gagctgttca tgaataatta ttttcggatc tataccaatc ctgatgtgat
    25381 cggtgtagag atgggggcag ctttgaaaaa tattattgct attggtgctg gcgctattca
    25441 cggcttaggg tttggcgata atgcaaaggc agcaatcatg acgcgcggat tagctgagat
    25501 cagccgttta ggtgtagcaa tgggtgccaa cccgctgacc tttatcggat taagcggaat
    25561 aggcgatcta gtcgttactt gcacaagtgt tcattctagg aactggcgcg caggcaactt
    25621 gttaggacaa gggcagcccc tagaagaggt gctagccaat atgggaatgg tcgttgaagg
    25681 tgtgaatact acccaagcag cgatggaact agcccaaatg atggaaatcg aaatgcccat
    25741 cactcaaaca atctatgaag tgctgtatga acaaaaagaa atcaaaacag ccgcaaaaga
    25801 aatcatgtta cgtgatggaa aaaaagaaaa tgaattctca ttaacaattt tttgaaggag
    25861 cgaatgtata tgaaagttaa aaaagcagtt attccagcag caggattagg aacaagattt
    25921 ttaccagcaa caaaagctat ggcaaaggaa atgttgccaa ttgttgataa accaacaatc
    25981 cagttcatcg ttgaagaagc gttgaaatca ggtatcgaag acatcttgat cgttacagga
    26041 aaagctaaac gaccaatcga agatcacttt gattcaaata ttgaattaga aacaaaccta
    26101 agtgaaaaag gaaagaccga attattgaaa ttagtagaag aaacgacaga tgtcaacttg
    26161 catttcatcc gtcaatctca tccaaagggt ttaggacatg ccgttcttca agcaagagcc
    26221 tttattggaa atgaaccatt tgtcgttatg ctaggcgatg atataatgga agacgaagta
    26281 ccattgacac agcaattgat cgatgactat gagcgtacac acgcttctac gattgccgtt
    26341 atgcaagttc ctcacgatga aacttcaaaa tacggaatca tcaacccagg ggaagtactg
    26401 gaagatgggt tatacaatgt caaaaacttt gttgaaaaac cagatccaag caaagcacca
    26461 agtgatttag ctattattgg gcgttactta ttgactccag aaatctttga tgtattatca
    26521 gaacaacaac caggtgctgg aaatgagatc caactaactg acgcaatcga tacgttgaat
    26581 aaaacacaac gcgtatttgc ccgtaaattc acaggtaaac gttatgacgt tggtgacaaa
    26641 tttggtttta tgaaaacaag tattgaatat ggtctgacac atccagaagt aggggcacct
    26701 ttgcgtgaat acatcatgtc tttaggtaaa acattagaag cagaaggaag caagatcaat
    26761 cataatccaa aaggaataac agaaatcaaa gaagaaaaga aaaaataatc tttttttcta
    26821 acgagcttca gctgctaatt gaataaaaag tagttgaagc tcgtttttat ttgtttaaaa
    26881 aacacgaaaa tgctatcctt atagaaaaga gagacaagaa gggagtttga tcatgtcagg
    26941 aggagaaatt gcaggattga tcgcagcaat cgcctttgcg atacttgtcg ttttcatcgt
    27001 tcgcgtattg ttgcaagttt ccaaaacttt agaaaaagta gaccagactg tcgcagaagc
    27061 aaatacgaca attgagatcg tcacacaaga cgtagatctt ttatctagac aagtagaagg
    27121 cttgctagtc aaaagtaatg agctgctctt ggatatcaat ggaaaagtcg caacgatcga
    27181 tccattgttc acagcagttg ctgatttaag tgaaagtgta tcggaactta atcattctag
    27241 taaaaacatc gtgacgaaag tcggcggaat cggaaaaacg acagctaaag cgactgttgc
    27301 cggaaaagtc ggtggaacag cgatgaaatt ttttaaaaac aaaaaacata ctgaaacgac
    27361 aggaggaaaa taagaatggc taaaaaaggt ggatttttat taggtgcagt agttggaggt
    27421 acagccgcag caatcgccgc attattgtta gcacccaaat ctggtaaaga acttcgggat
    27481 gaattggctg ctcaagcaga tgatttgatg gacatggctt cagattacac agatatggca
    27541 aaagaaaaat catctgagtt aacaggtatt gcaaaagaaa aagcgcaagg tctttctcaa
    27601 caagcagggg atctagcagg caatgttaag cagaaggtaa gtgaatcagc agaggaagca
    27661 ggaagtgaat cagatgatat cttgttaaac ctcaaagaac aatcagctga tttatctaat
    27721 cgtttcaaaa aaacagcaga agatctgaaa aagccagcag acgaattagg tagtattgct
    27781 aaagatactt cagaagatat catgatcgat gtaaaagatg ctgcagataa agcaggagag
    27841 acggtcaatg aaggaatgtc agaagcaaaa ccagttgcag atgacacaaa agaaatgttg
    27901 aaaatggcaa aagaagatgc aaaagaagct aaaaaagaaa tgaaagatac aatgacagat
    27961 tcgactacca atcactaaga ttactcattt ctagaataaa aaaggtgaga gcggaccagc
    28021 tctcaccttt tttattttca ttactctaaa acaagtaatt cttttggtgt agtcgtgaat
    28081 ggcacacaac catcacttgt cacatacaca caatcttcga tacgtacccc tactttttca
    28141 ggaatataga ttcctggttc aagagagaag cacatccctt cttcaatcac taagtcgttt
    28201 ccttctacaa gagaagggaa ttcgtggacg gttgttccga ttccgtgacc taaacggtga
    28261 ttgaaatatt cgccgtagcc atagctgttg atcacgtttc gtgcgatttg atcaagttca
    28321 cctgctgtca cacctgggcg aactgcctct tgtgcggcaa gctgtgcttc aagagtgatg
    28381 ttatagattt tttcttggaa ctcagttggt ttttgataag caactgtacg agtagcatca
    28441 ctgcaatagc cattccaaat aacgccaaga tcgaataaca ctagttcatt tggtgaaacc
    28501 ttcgtgcttc ctggtgtacc atgagggctt gcagcatttg ctcctgcaag gactaatgtg
    28561 tcgaaagaca tttgtgaaac accttgtttt tttaattggt attcgatttc tgcgataatt
    28621 gcttgttcag ttacgccttc ttttactgtt ttgaagccaa tttcaaaggc aacatcggcc
    28681 catttaccag cttcgatcag tttgtctttt tcttctaccg ttttgatcag ttgcagacgc
    28741 tggataatag aagttagatc ggtgtaagaa tctgtacctg tcaagatatc agagatagca
    28801 tcgaagcgat cgacagtcag agcattcttt tcaataccta cattaccagg ttgcccatag
    28861 cgtgcgcgaa gctcttttcc gatgatctcc caaggatttt cgctgtctaa gtagccacgt
    28921 acatcgtacg cccagctgct gttttgagca tcttcaactt ccagagcagg agtgaaaagg
    28981 aaaggatctt gttccagagg gataaaaaga gctagtacac gctcgtgagg atcactttca
    29041 tatccggaaa agtaagcgat gtggccaggg tcgctgatat aagccaattc tacttggtgt
    29101 tgtgccatcc attgacgtag ttcattgatt tttacgttat tcatttggca acctactttc
    29161 taaattaatt ttgtattcaa taattgtacc actgattgat taaaagacca acgttcttaa
    29221 aactgaaaaa agtaaaaatt ttcatgaaaa cagagataaa acggttgcaa ttgttgagat
    29281 tatttgatat cctattttag aaatgtaaga cgtattttca gaaaacatat aaaatatgaa
    29341 taggagaaca caaatggaaa agcaaacaat cactatctat gatgtagcga gagaggcaaa
    29401 tgtttcgatg gctactgttt cacgtgtcgt aaatggcaat ccaaacgtca aaccagcaac
    29461 aagaaaaaaa gtcttggaag ttatcgatcg cttggattat cgtccaaatg cagtcgcacg
    29521 tggcttggca agtaagaaaa caacaacagt tggggtaatc attcctgatg tcagcaatat
    29581 gttctttgcc tctttagcac gtggtatcga cgatgtggca acaatgtaca aatacaatat
    29641 catcttagca aactcagatg gcaacgatca aaaagaagtc aatgtattga ataatttatt
    29701 ggctaagcaa gtggacggcg tgatctttat gggtcaccat atcacagacg aaatccgtgg
    29761 agaattttca cgttcaaaaa cgcctgttgt actagctggt tccattgatc cagatgaaca
    29821 agtaggtagc gtaaacattg attatgtgtc agcaacaaaa gatgcagtaa ataaattagc
    29881 aaaaagcggc aataaaaaaa tcgcttttgt cagcggtgcg ctgattgatc ctatcaatgg
    29941 tcaaaaccgt ctaaaaggct ataaagaagc attaagcgaa aacaatctac catatagcga
    30001 aggattgatt tttgaggcac aatacaactt taaagatggt ctgtctctag ttgaccggat
    30061 ccataatagc ggtgcaacag ctgtctatgt ttcagacgat gaattagcca ttggtatctt
    30121 ggatggttta ttagaccgcg gcgtaaaagt accagaagaa ttcgaaatca tcacaagcaa
    30181 caattcttta ctgacagaag tagctcgtcc tcgtttgaca agtatcacac aaccattata
    30241 cgatttagga gcggtatcca tgcgcctatt gacgaaaatg atgaataaag aagaagtcga
    30301 agaaaaaacg attatcttgc cttatggaat cgaagaaaaa ggatcaacta aataataaaa
    30361 gatcaatcat ttaaaggttg ttccaaaagt ggtcaacttc tggaacaacg tttatacgag
    30421 aaagggggtt atgacaaaat tttgtcataa cccctttttt tttgtgactt taaaaaaaga
    30481 gaaaatggcg gaaacaaacc ttacgtccat cgtatacgac acaatctgtg cgtagatgct
    30541 acattttgtt cactactatc aaaattactt taaaatgaaa acgtgataaa aaagaaagta
    30601 gaaaagtaga taagtaactc taaaaaatcc aaaaaaatcc aggctcgatt gcgtacttat
    30661 cttaaaggag aaacaatcca tcatatataa cccgaaagga gacttctatt tgcctaagaa
    30721 aagacgaaag accatagtca tcattttgac cattcttact ataggaatcg gagggaaatt
    30781 ttacatggac aaaagagaaa tgcaaagaca gaaagattta ctcgcagtag aaaaacagtc
    30841 cgtcaaagtt ctgaaaaata cctttgcgga tatcaaggaa gtgaagattg aaaaatctgc
    30901 tcgaaatgaa atgacgggtt cataccggat agttattcta atgactaata aacaagatca
    30961 atcgatttat ttttcttata gtttttggaa agaaagaaat gagataggaa gttacggaat
    31021 agttgatgaa aaaaagcaaa aagaaggaaa tacgctcaat aaagttaaag taacttactc
    31081 taatggaaat gaggaaagta tttaatgatt actgacaaac aatatagtga attaagtgat
    31141 gctgtttact ggctagatcc taaacataga gactatgtac ctgaaatgca agaaaattta
    31201 agttttaaaa ttaacggcac tatgtataaa atcctaaaaa tcaaaaactc cttcgacggc
    31261 atgcaggcga tggctgtagc gccaatcgtc catagcaaat tggagaaaaa tttcaaaaat
    31321 aaaaaaattc ctgcaaactt tcgcgtactt aaataatgaa ggtgtcaata cttacataaa
    31381 aagaaaggag gcacgttctt gtcaaggaaa ataagaaaac tcagcttagc cattttatta
    31441 atcgtcatat tagggatcgg agggaaagtc tatatggaca aaagagaagc acaaaggcag
    31501 aaagatttac tcgcagtaga aaaacagtca gtcaaagttc tgaaaaatac ctttgcggat
    31561 atcagggaag tgaaggtaga agaatttaaa aaaaaccctg ttaccggaag ttatggtgca
    31621 cttgtgacaa tgacaaataa tgaagggaaa tctgtttatt ttgattatag tttttggaag
    31681 gagagaaatg aacttggtgg ttttggcatt gagaacagag cggtacaaaa gacaggagtc
    31741 actataaaaa gagtaaaagt aattttttct aacggacagg aggagttagt atgacaataa
    31801 acgataagca ttacaatgat attagtgaga aggtttattg gctagatccc aaatatcccc
    31861 gctacaatga gggatacaaa aagaactctg ttaaagaatt tgctggtatg gaatttcaaa
    31921 tcctacaaat caaagactca ttggacggca tgcaggcgat gtctgtagcg ccaatcaaga
    31981 acggtaaagt ggatctttct caagtagtga ttgcttttgc aggaacgaac ttaagtgatt
    32041 ggaaagattt ggaaacggat gcaagaagta tcatgaatct ctacgggaat agaccaggag
    32101 caagtttttc tgaaaaagca acaacaaaca agattttatc cgttagtgga ttgaaaacag
    32161 cggggcaaat caattcagcg attgcatttg ctaatgaagt aaaaaaggaa tatggagaag
    32221 ctgctatttc tactaccggc cattcattag gtggattctt agcattatat gtagcagcag
    32281 agaaacaatg gaaaaatgtc ggcttcaacg ggccggaccc gtatgatctc ttatcaccag
    32341 aagcaaaaaa atgggtggaa gaaaatcccg gtatgctcac caattaccga aatcacgccg
    32401 attttatcgg taattttggt ggtaatggca caggtgctga agttcggatc agtatggaaa
    32461 cagcattctt gaatctgctt gcttcccaca gtttaacctc ttggaagttt gatgaaaatg
    32521 gaaagctgat tattcctgaa aatgaaaaca atgttaaagc tcgaaaacaa cagaaagaaa
    32581 accaagcgac ccagttgttt tcctatcagt tgcaagaact gaacaacata cgtaaaaaac
    32641 tacgattaag tggcggccgg ctgacagtta atgaacaaat ttacttagat gacacacaag
    32701 ctaggttagt agtggaaaag ttatcggcaa aaatgaaaag cgctatggaa gaagttatcc
    32761 gcatcaatca aagaggaatt tttgagctag agaaaaaatg gcaagaaggc ttgcggcaag
    32821 cacgtgttgt agccccttcg ttgactgaac aggaaatcat agaagcatta gctagtgtgg
    32881 gcgccacaaa agaaaactta gtcgattctg cgaaagaagt ctatctgcta cgaatcaata
    32941 aggcaagacg tatgggggag gcctttgata cattggcgaa ggagatccaa gacaaaatca
    33001 atgaaatcgt ggcacgagat cgagaattag cacagcaatt caattaaagg agaagtagat
    33061 gaaactagaa gaattggaaa gagattatcg aagtgaacga agacaattag aagctcaaga
    33121 agatgaattg atctacttta agaatcaagg attacgattg atggagcaag aggagcagcg
    33181 actgcatcat gtattaaaga acttagcttt agataatgag cctctgtttc aagcaagacg
    33241 aagttattcg aattatcagg agcattatca acaagcccta caagtagaac gacgaaaact
    33301 ctatcagcag caagatgaac tagaacgttc ctatcgtcaa aaaatcagac aaataactat
    33361 ggagaaatca tcttatgaat gaatttttaa tgcaattact aaaagaatta gagaaaaatc
    33421 tacatcgatc aaatgtacgt tcagttggta tggggatatc tcagcaaatt tgggcagaaa
    33481 aacgattgac agatcaaaac taccaaatga ctgcagaaga agctgctcaa gaattttcta
    33541 accgacatgt acacttgaaa ggatcagtaa aagggcaatt tgcagaaaaa ctaactgaat
    33601 tattccaaag acaagaaaag aaattaaaac agtttcgtta gtaaagttat atagaaaaat
    33661 tttgtgaaaa tg
//
LOCUS       DAPBAF010000033        33505 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.033, whole genome shotgun sequence.
ACCESSION   DAPBAF010000033 DAPBAF010000000
VERSION     DAPBAF010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 33505)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33505)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33505
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.033"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            <1..189
                     /locus_tag="RD451_001795"
     CDS             <1..189
                     /locus_tag="RD451_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HDT7567054.1"
                     /translation="NSNGILRRNGLPKSIDFREVNQTFISSVSNQRNHIPRKSLNYRT
                     PIEIFLSYVQEAFYSSLI"
     gene            complement(1055..1585)
                     /locus_tag="RD451_001796"
     CDS             complement(1055..1585)
                     /locus_tag="RD451_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transferase"
                     /protein_id="HDT7567055.1"
                     /translation="MRLGLIIKNILNLPKTIYFNYKFLHISDAWRLPILVHRKVRITR
                     KSRGKIEIVLQSGKIVYLGFPVLNTAGNEETIISIEGILRIQGPAFIAQGAHIDIRKN
                     AVLDIGSKFNSTGKMSIICFKEIQFKDGCTVSWDTLFMDTDSHTIFELNTHRILNKNN
                     KIVIGKHCWIGAKSVI"
     gene            complement(1582..2199)
                     /locus_tag="RD451_001797"
     CDS             complement(1582..2199)
                     /locus_tag="RD451_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HDT7567056.1"
                     /translation="MIIVIAEIITDILYKLYEPFGFAVLLTILGLVYFMYATDGIAAG
                     EGYKRILMELYLHLKKDRKYRKVCALIFYTAMILFTTLINRTIWLNPLSDVMGDWWIY
                     KYNTTTGTKELSTACLENIILFIPYVYMVMSIKYENIKKPKIWSSIVYGGKIAFYFSA
                     IIEFLQLFLRLGTFQISDFVYNTLGGILGVILYKLILITKRDGER"
     gene            complement(2781..3002)
                     /locus_tag="RD451_001798"
     CDS             complement(2781..3002)
                     /locus_tag="RD451_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transferase"
                     /protein_id="HDT7567057.1"
                     /translation="MGSSERIKIGNNVFIGMKSRILKGVHIGNNVVIGANSLVNKDVS
                     DDCVVAGNLAKVIMSLDEYYKKINNMKNP"
     gene            complement(3180..4712)
                     /locus_tag="RD451_001799"
     CDS             complement(3180..4712)
                     /locus_tag="RD451_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HDT7567058.1"
                     /translation="MIINRKQNAKRNIITGTIFKLYQIIIPFFMRTLMIYQMGMEYAG
                     LNNLFTSIFQMLNLAELGIGAALTVSMYKPIAEDNRKEICALLNAYKKYFSIIGWIVF
                     TLGLLCIPFLRFLVKGSIPGNLNMTVLYLMYLINTVLSYWLFSYRKSLIYAHQRNDVI
                     NVSMLITFTFQFVMQAYVLIFLKNYYLYLLASILGQIVLNLMCAVVSQKMYPDYTPVG
                     ELEKETIDDIIKKVKGLVTNKVGGTILRSSDSIIISSFLGLSVLAIYQNYYFIISAIM
                     SIFAIIYESCIAGIGNSLIVESQEKNYIDFCDITTIIGWFLAISCACFITLFQPFMII
                     WVGSDNLMSISFVIFMIVHFFLYEIDQLIGLYKDAAGIWYADRFRPLITAMINIVLNI
                     ILVNWFGLYGVLAATIVSVLLVDLPWLLYNVFQNIFKFESAGKYVWKLISLCVIAFVA
                     SYLSYFACSYVNIGNFKVISLVINLVISVVISILVILLFNIRNKKFKYILKVLTSVLV
                     KR"
     gene            complement(4848..5933)
                     /locus_tag="RD451_001800"
     CDS             complement(4848..5933)
                     /locus_tag="RD451_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HDT7567059.1"
                     /translation="MKKICFISGVISRSGGTERVGSIIANSLSDLGYDVTILSFWNSG
                     EPYFGLDKTIKVDYMLNPKTEGKLYRTYLYPVWKLHKYICKNEFDIVIDIDTLLSLYT
                     TRAIKGTKCKLISWEHFNYWTMEMLKEKKRFKAKKLIKKYAKRLVVLTEEDRQKHIDE
                     YSLSEDFVITMPNPCISNIEYEYHYDKKRFLAVGRLVEEKNFADMISAWKIVEKKVDD
                     WDLIIVGKGELEKDLRQQIKDLNLQRVTIAGHSDHVEEYYKSASCYVLSSVYEGFPMV
                     ILEAQSYGLPVISYDCKTGPRDLVHHNFNGMLVEDKNIDQLAKSMIMFTKNTDLAMRM
                     SLNAYNNVQKFNLKEITKQWVALIENV"
     gene            complement(5948..6667)
                     /locus_tag="RD451_001801"
     CDS             complement(5948..6667)
                     /locus_tag="RD451_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HDT7567060.1"
                     /translation="MIPKKIHYCWFGGNPLPKKDRKCIESWKKYCPDYEIIEWNESNY
                     DLNKNRYMADAYKERKWGFVPDYARFDIIYNHGGFYLDTDVELIKSLDILRENHAYMG
                     FEGEIWVNGGIGFGAEEGHSVIKGLRDIYDSLSFYQNDGTLNLKPSPYYITDYLESIG
                     LVRDNSEQIINGLHIYPTDYFAAKDYDTGKIYKTSNTISIHQYNASWKTPKQKFVYRL
                     KSTIGQKKFNRLLALKKFLHL"
     gene            complement(6664..7974)
                     /locus_tag="RD451_001802"
     CDS             complement(6664..7974)
                     /locus_tag="RD451_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HDT7567061.1"
                     /translation="MRISIKRWSGADWTLFTLAFFAISIVLVYTFNAPRAILYLGDII
                     NIFVLLNALSFRRRKGIYASKNEMLIVLFLLVSICSSVINLENIGLIIWGIRNNTRMF
                     IVYINCATYLTIKDYYKVFAIIEKLFWISLPLCLIERFMVTYPTGTIVGDMIGGVFWN
                     YSGCNMPLNLILCVTVTVVTIGYFKGEKNFIHFILCVCAALFMSALAELKVFIPELFI
                     IFVAIVFTLKVDFKVVIKILSCVILVSIVLSFFITIFITLNDNGQSYADNFTIQGLLE
                     YASRDSGYDGVGDLNRITGISRVVDEIFNNNFRLVLMGVGIGNAEFTNFFVSEFYKSF
                     GNLHYQYFHHIWLFIEVGILGVSIFLFFIIKTFFNAKRSFMKDKDASLVKVIAIMSVF
                     FFVYNTTLRGETTGPLIYMILAMPEVVKRKEHYYSEKNTKGEIL"
     gene            complement(8001..8591)
                     /locus_tag="RD451_001803"
     CDS             complement(8001..8591)
                     /locus_tag="RD451_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
                     /protein_id="HDT7567062.1"
                     /translation="MEISSKEYLKAVLRMEKNLYIESKGQHTKLLKIMKSHPDYNAWR
                     YTRRMRITSYYYSKRKKNIIYAIMYIVSCRRMNSLGRKCGIECGENVFDEGVRFYHTQ
                     GIVINGNAIIGKNCYLYGNNCIGNDGIDPKCPVIGNNVRVCVGAKIIGNVKIANNVVV
                     AAGAIVIKDCLENGAILAGVPAKIIGYVNLTKVFLE"
     gene            complement(8909..9970)
                     /locus_tag="RD451_001804"
     CDS             complement(8909..9970)
                     /locus_tag="RD451_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDT7567063.1"
                     /translation="MNSSDLISVIIPVYNVEKYVGSCLESVCNQTYKNLDIIIVDDGS
                     KDSSNKICEDYALKDSRIRIIHKNNAGLGLARNTGLEHVKGKYVAFIDSDDFVAANYI
                     EAMLNGIKRSNADTCYAGYYEYYDDNNIISKPARYDSTIFTNNAIIEKVLLGMIGTEP
                     SYKVDFILPMSVWHALYSSEIIQQHNIKFPSERDYISEDIIFHISYLQHSKITSFIKD
                     CIYYYRCNNNNSLTHNFRDNEFDCNIELVKKIEGDLSYILENEIFVNKTRRLLLGRCR
                     TCIQKAVRYASFNKEFDLNSYLSKILMNDELIACIHSYPYKQNPIKQRIFNYFLLNQS
                     IIGVKTLAYLSGMGRNRRF"
     gene            complement(10538..11605)
                     /locus_tag="RD451_001805"
     CDS             complement(10538..11605)
                     /locus_tag="RD451_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HDT7567064.1"
                     /translation="MQRVLMIGNDSSVKGGITSIITQMLNFNWEKKNIEMTFIPSYKG
                     GNAIFKSLYFMYAFAKIIGISLLSKPNIIHMHMSYRGSFSRKYVLNKWFRLLNIPVII
                     HLHGSEFKKWYDSVSVKKQNQIRLLLRESDSTIVLGEKWKKIIKEIEPNCKTVVVENS
                     IVVPEYTIKWNSKMCRFLFMGVLIKRKGVHDLVEAVKNIAEQYPEKKFIFEIAGAGDE
                     EISLKELIEEYNLQSYFEFTGWVVGEKKEECYRRSNVMILPSYNEGLPISILEAISYG
                     MPVIATDVGDISSAVRDGENGYLFQPGDVSALTSAILKINDKDKYVKFSRCSKDLAIT
                     KFNDGNFFDRILNLYQKGSKE"
     gene            complement(11625..12104)
                     /locus_tag="RD451_001806"
     CDS             complement(11625..12104)
                     /locus_tag="RD451_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta(1,3)galactosyltransferase EpsH"
                     /protein_id="HDT7567065.1"
                     /translation="MIFITLGSQKFQFDRLLKAIDDLIEKGVIIESTFAQSGYSDYKP
                     LNYSYKAFLNRDEFTETMQKAEMVITHGGTGAIIGAVKKGKRVIAVPRLAKYGEHVDD
                     HQLQLIRQFDEMNIIYPCYELENLEDAVKETRVRMFNKYVSNTETIINSIEVLIEKI"
     gene            complement(12121..12582)
                     /locus_tag="RD451_001807"
     CDS             complement(12121..12582)
                     /locus_tag="RD451_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HDT7567066.1"
                     /translation="MNKKICFAASSGGHYEQLMMLKPLMEKYESFVITEQTEYSAESK
                     GEKTYYMRQVNRKEKFFLCTILINLFKSIIIYIKEKPDLVICTGVLAMIPICLITKMM
                     GKKLIYIESFAKVTSPTQTGKLMYHFADQFYVQWETMLQFYPNAIYLGGIY"
     gene            complement(12596..13846)
                     /locus_tag="RD451_001808"
     CDS             complement(12596..13846)
                     /locus_tag="RD451_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HDT7567067.1"
                     /translation="MKKKYNIAVAGTGYVGLSIATLLAQHHQVTAVDIIPEKIELINK
                     RKSPIQDEYIEKYLTEKELDLTATLDARSAYKSADFVVIATPTNYDSRTQHFDTSAVE
                     SVIEVVMDVNPDTIMVIKSTIPVGYTESVRETTGSKNIIFSPEFLRESKALYDNLYPS
                     RIIVGTDMTDERLLNAAHVFATLLQKSAIKENVDTLFMGFTEAEAVKLFANTYLALRV
                     SYFNELDTYAEMKGLNTQQIINGVCLDPRIGTHYNNPSFGYGGYCLPKDTKQLLANYA
                     DVPGNLIEAIVESNRTRKDFIADRVLQMAGYYNYAEYNQYDVNRENPVLIGIYRLTMK
                     SNSDNFRQSSIQGVMKRVKAKGATVVIYEPALKDGETFFGSKVINDLEQFKAMCDSII
                     ANRYDTCLDDIKEKVYTRDIFQRD"
     gene            complement(14224..15675)
                     /locus_tag="RD451_001809"
     CDS             complement(14224..15675)
                     /locus_tag="RD451_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HDT7567068.1"
                     /translation="MYKKSSRGWVKHIDFIILDLLCIQLAFYLSYVLRQVDWNPYVIP
                     MYQNMAVFIELADLLVIFMFEAYRGVLKRGYYIEFASSVKQAIMLVLLGSLYLISVQG
                     GNDYSRVVLFLMGGLYVVITYITRLLWKHYLKHKMKNEGNKSLIIVTSSSIAEVVIRN
                     VKEHNYKMYKINGVIIIDKSMIGEDVEGVTVVSDSKNAADYLCQGWVDEVFIILNKST
                     SCMKEFIERCSEMGLTVHLNLAKVSDSALGKQSIGRIGEYTVLTTSINVMTTQQAFIK
                     RTIDILAGIVGCIATGIIFIFIAPLIYINSPGPIFFAQERIGQNGKPFKMYKFRSMYM
                     DAEERKVELMKENKMSNNLMFKMEFDPRIIGNKILPDGTKKTGIGQFIRSTSLDEFPQ
                     FFNVLTGKMSLIGFRPCLKSEYEEYDYHHRARIAIKPGITGMWQVSGRSDITDFEEVA
                     KLDTEYIKNWSMGLDFKILFKTVKTVLQRGGSM"
     gene            complement(15996..16760)
                     /locus_tag="RD451_001810"
     CDS             complement(15996..16760)
                     /locus_tag="RD451_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HDT7567069.1"
                     /translation="MIDLHCHILPGIDDGAENLEASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIHRDEILFTDLD
                     DTYLLIEFPTLEVPLYAERLFFELLELGKTPVIVHPERNVHFREDPNHLLPFLDMGCL
                     AQLTAPSYVGVFGKDIQKTAKTMVKHNLVQMAASDAHGVSKRTFYLKECYEQIAKDFG
                     KEKVVQMKQVAKDLINGDEISYPVYEEVKKKKFGLF"
     gene            complement(16788..17486)
                     /locus_tag="RD451_001811"
     CDS             complement(16788..17486)
                     /locus_tag="RD451_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HDT7567070.1"
                     /translation="MARTQKQKAAQTHAVSLITLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVVYKTFQLNNAS
                     GLSTALSSSGSVADVIQRTPVENLSILPSGPKPPNPSELLSSPRMDQILSEARQLFDV
                     VIFDMPPVVAVTDAQIMSLKTDGTLLVVRENMSRKESLTKAKELLEMVQARVLGVVYN
                     GAEHSKDAGYYYGN"
     gene            complement(17498..18277)
                     /locus_tag="RD451_001812"
     CDS             complement(17498..18277)
                     /locus_tag="RD451_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein kinase"
                     /protein_id="HDT7567071.1"
                     /translation="MEETISLKEIFETLRKHLVIIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     EQIKDAISVNQAENSQMFSIQAISTNAVAAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLMTGLMLGMMVGVGLAFLLELLDRTVKDEKYVTDTLGFPILG
                     TVPEMSAKELNAGIRKKGTAPARPKATNDKTAPSRRSRSRV"
     gene            complement(18293..19237)
                     /locus_tag="RD451_001813"
     CDS             complement(18293..19237)
                     /locus_tag="RD451_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HDT7567072.1"
                     /translation="MARRRRKSRGKKIFLIILAVLIVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVATVSPEDK
                     QTTIVSIPRDTYVDIVGRDTKDKINHAYAFGGAAMAMDTVQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFPIGKITLNGDQALSYSRMRYEDPNGDYGRQGR
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMNFDEMKKIALDYREAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            complement(19283..20062)
                     /locus_tag="RD451_001814"
     CDS             complement(19283..20062)
                     /locus_tag="RD451_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567073.1"
                     /translation="MEKPFVKLLATVAVGTGAIVICLFGYHLNNQRQYHQRINYAESA
                     ITNQKDTVTSLSKEVDKLYSTKEKIFLNPEITEETVSNLSHKLSSIKLSADDYDIKES
                     ELPKEAAAIQEEKKAVLTQLEDAESKLKIQTAVNKLFTKNVSNWQQAVDDVIIKEKLA
                     SADVAHVRENMSFFKDSAWKTVVMQYLGFADTQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTALSQIEQIRNEKIRAAYATKAQTVAQQMGYSNISY"
     gene            complement(20442..22517)
                     /locus_tag="RD451_001815"
     CDS             complement(20442..22517)
                     /locus_tag="RD451_001815"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HDT7567074.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKEAKEVLTGLAGVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEVIPFEILDVKTGRASRGHRFLGEDVTFAHAKEYEEKLNEQFVIASPQKR
                     QEMIVTQANELAEKNHWVIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLEDVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGELPQSTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISD
                     VISKDTDRFGIGLSEGQQQVIDFIKGRLRQLLTTKNIRHDVIDAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAQLEKQSEVDPELFENDAEKELHKAVEA
                     MKASFADQTIHENYDQLVALRPLIENYFDQTMVMADEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
     gene            complement(22519..23436)
                     /gene="glyQ"
                     /locus_tag="RD451_001816"
     CDS             complement(22519..23436)
                     /gene="glyQ"
                     /locus_tag="RD451_001816"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HDT7567075.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRL
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARAVA
                     KIFVAEREKLGFPLLNKNTANPETVKEAE"
     gene            complement(23822..24640)
                     /gene="recO"
                     /locus_tag="RD451_001817"
     CDS             complement(23822..24640)
                     /gene="recO"
                     /locus_tag="RD451_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HDT7567076.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKEIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRHIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKYGGVICERHWSMDDHRYHADPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRELIDQLYDEYVGIHLKSKKFINQMKSWAHVLKTSEKDMSEKEKETPEKEE"
     gene            complement(24783..25682)
                     /gene="era"
                     /locus_tag="RD451_001818"
     CDS             complement(24783..25682)
                     /gene="era"
                     /locus_tag="RD451_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HDT7567077.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            complement(25697..26092)
                     /locus_tag="RD451_001819"
     CDS             complement(25697..26092)
                     /locus_tag="RD451_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HDT7567078.1"
                     /translation="MDLKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFGIL
                     ALFMGVIFQLDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKDMA
                     AGAVLVTACFTVIVGLILFVPKIYHLLFN"
     gene            complement(26076..26552)
                     /gene="ybeY"
                     /locus_tag="RD451_001820"
     CDS             complement(26076..26552)
                     /gene="ybeY"
                     /locus_tag="RD451_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HDT7567079.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLELPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISTER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            complement(26581..28773)
                     /locus_tag="RD451_001821"
     CDS             complement(26581..28773)
                     /locus_tag="RD451_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HDT7567080.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIVCGVTFSSVKQKAIDF
                     REGQVAEESIRANKTIENTEETEQRRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDTINKSYNGKVDKAKEDENIPKPTTEERIATLKKNFENVNAENVAFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEDQIQYLNVTTEQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNAGERTKYVLFYVTAMSVSVV
                     LMKFFQLFQTEQAAYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTVILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIIYQGMSFGD
                     ATTWLTLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICRQHHGTTLMRYFYVKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKSEVEKIKEEQEE"
     gene            complement(28797..29768)
                     /locus_tag="RD451_001822"
     CDS             complement(28797..29768)
                     /locus_tag="RD451_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HDT7567081.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            30473..31852
                     /gene="brnQ"
                     /locus_tag="RD451_001823"
     CDS             30473..31852
                     /gene="brnQ"
                     /locus_tag="RD451_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HDT7567082.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGANWV
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYNSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFHPMGNLNQSAADTYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKTPFVYQVTMLFAAVPAVLDM
                     LANSPALVSQQRVVASMLEFYHHHVPFAALGLGWMVPTLLGYAGSLLFYYAYRLSGYK
                     QEANELPEE"
     gene            32134..33474
                     /locus_tag="RD451_001824"
     CDS             32134..33474
                     /locus_tag="RD451_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HDT7567083.1"
                     /translation="MSYSEFTKELLDILDLNLIFHEDAFRKERINDETCFVFDGTLTY
                     QPEECFHCHYQNKQTIIKWGWKKVSILLNDVSNYKTILRINKQRFKCKHCGKTFLAED
                     SVSDRRCSIARRVKQAILELLSEPLSMSLIARMKHISPTTVIRILRSLRPKTVSLNQP
                     LPEVVCFDEFKSVKNVSGAMSFVMMDGKTHQLIDIVENRQLNPLRDYFLRYPRKVREQ
                     VRLVVSDFYTPYRTLVKECFPNARIVADRFHISQHIGRAFTNHRIQVMKTFKKRDRRS
                     KHLKKYWRLLQKNAWELKGQHRYWRPSFRDHLTEAEIVDRLLSYDDSLKRGYEVYQDF
                     LSAIRRQDVPEFVALLKEDYKELPEHYQPVFTTFKKYRTEIKRALRVPYSNGPIECLN
                     NHIKVLKRIAYGFRNFQNYQERIFLYRGKYFKKTKNTTQLTKARTTTRLDKIAV"
BASE COUNT        10084 a         6867 c         5059 g        11495 t
ORIGIN      
        1 aattctaacg ggattctgcg tcgtaatgga ctgccgaaat caatagattt tagagaagtg
       61 aatcagacat ttatttccag tgtcagcaat caacgcaatc atattccaag aaaatcattg
      121 aattacagaa caccaatcga aatatttttg agctatgtac aagaagcatt ttattctagc
      181 ttaatttgac aaatcatata atttaaaatt aacattgatt ctcctatgaa aatatctttt
      241 acctttctcc tgtgaaaagg aaatttcctt ttttatagtg ttattgatat aatcagaata
      301 ttcatcaaac tctgtatctg gagttaaaaa tctacagtaa catctataag ctttgctagt
      361 aatcttcttg ggttctctct ccattgtcaa gcaacatcaa aacacctact tactattcga
      421 ttcttttctg ccaaaaacga gtcagcatca ctcacaactt atgtgttgct gactccgact
      481 agtcctttgt tcaatatcaa cttattaaac agatataata tttttcttta tttcgtatac
      541 tccaagactt ccatctttct ttcatcttat ctctgaaaaa aacacagcaa agtgccctta
      601 ataaatatac attagaattt gcaaattttt tcatcttaag atatatccta ttcatattct
      661 ttacaatcct aatgggtgat tacaaatcta tttagttcaa gttctacatt ataaacacct
      721 ttcttgatag tatcatctgc tgcacaagcg atgtcgatcc acttattagg ggatttacgt
      781 gctcaaaagt ggctattcct tttgggaagt ccatccataa taatggtcca tggatttttt
      841 tagggtcttg tcgttcaaat ttctcaaaaa ctttattata cttccatagt tttataatta
      901 tttggtttca ctttggctcg ttcaaacacc aacttgtatt tcttttcaac gttcgaactg
      961 gagccccccc tataatctca ttattatttt catgactttt tactaccgtg gaattacaag
     1021 caacaacaat attatctgct aaatgaacac ctttctatat cacgcttttt gctccaatcc
     1081 aacaatgttt acctataact attttattat ttttattcaa aatcctatga gtattcaatt
     1141 caaaaatcgt atgtgaatcg gtatccataa ataatgtatc ccacgatact gtacagccat
     1201 ctttgaattg aatttcctta aagcaaatta tactcatttt tcctgtcgaa ttaaactttg
     1261 acccaatatc taaaactgca tttttcctta tgtcaatatg agccccttgt gcgataaacg
     1321 ctggcccttg tattcttagt attccttcaa tacttataat cgtttcttca tttcccgcag
     1381 tatttaatac tggaaagccc aaataaacta tttttccaga ttgtaatact atctcaattt
     1441 tccctctcga tttgcgtgta atccgtactt tacgatgcac caaaataggt aatctccacg
     1501 catctgaaat atgaagaaat ttataattga agtatatcgt tttaggtaaa tttaatatat
     1561 tctttattat caatccgagt ctcatctttc accatctctt tttgtaatca aaattagttt
     1621 ataaaggatt acacccaata taccgcccaa cgtattatat acaaaatccg aaatttgaaa
     1681 cgttcctagc ctcaaaaaaa gttgtaaaaa ttcaattatt gctgaaaaat aaaatgcaat
     1741 ttttcctcca tatactattg aggaccatat tttgggtttc tttatatttt catatttaat
     1801 agacattacc atataaacat atggaataaa aagaataata ttttctaaac acgctgtaga
     1861 taactctttt gttccagttg ttgtattata cttataaatc caccagtctc ccataacatc
     1921 agataaagga tttaaccaaa ttgttcgatt gattaatgtt gtaaataaaa tcatcgcagt
     1981 atagaatatc aaagcacaaa cttttctata ttttctatcc ttctttaaat gaagataaag
     2041 ttccattagt atacgtttat agccctcacc tgcagcaatg ccatctgttg catacataaa
     2101 atagaccagt cctaaaattg tcaataaaac agcaaaccca aagggttcat ataatttata
     2161 taatatatct gtaataattt ctgcaatcac tattatcata attatttctc caatatcaag
     2221 tatacactta tcgcttccaa ttacacatga tcatattaga gtgtattatc acattctcta
     2281 atattcaatt tatttttcct aaaatattcg aaataatcgt cttgataacg agtaagtatt
     2341 tttatacgat tgataacata gtaacaatat ttttaattat agtaaaaaat catctgcctt
     2401 tttcatccac ctaatcttat ttttcatttt attcaacatc cttaaataaa cttccgttcc
     2461 taagctctat aatatcttct taaaaaataa tattatggtg tcgttttcaa actcgtaatc
     2521 ttttacattg gaaaaataca tacttttctc aatgtagcaa ctcctatctc acagtattca
     2581 aaaattcttc aatattatga aatacttgtg catgttcttt aaataccttg tcagtctgtt
     2641 tataatcccc tactaaattt tgcattgctc ccaactcttc gacaaattgt catctccatc
     2701 tgtaaacagc cctaaaaact catataatgc tttttcatca atatttttcc catattattc
     2761 tcggtatagt ttcacaagtt ttacggattc ttcatattgt ttatcttttt ataatattca
     2821 tctagggaca taattacttt tgctagattt cctgcaacaa cacaatcgtc tgatacgtcc
     2881 ttgtttacta aactatttgc acctataact acattatttc ctatatgtac accctttagt
     2941 attctagact tcattcctat aaaaacatta ttacctattt tgatcctctc cgatgatccc
     3001 aaagcttctc catactactt ttaaaaccga tcaatcataa acatgagtca aaattgtaac
     3061 tccttcatat catctccaat ttcaacaaga gtcttcgttg gaacaaaaac tatacatcgt
     3121 tcgcctattc ggcagcctaa aaattgtagt tactttatat atcattctga tgtctcttct
     3181 catcttttta ccaataccga cgtaagaact ttcaaaatat acttaaactt cttattacgg
     3241 atattaaaca gaagaataac taaaatcgat atgacaaccg atataactaa atttatcact
     3301 aaacttatca ctttgaaatt tccgatatta acatacgaac aagcaaaata acttaaataa
     3361 gaagcaacaa aagctattac acacaaactt atgagcttcc aaacatattt acctgccgat
     3421 tcaaatttaa atatattttg gaaaacatta tataataacc agggtaaatc aaccaacaat
     3481 actgaaacaa tggttgccgc caaaactcca tataatccga accaattaac gaggatgata
     3541 tttaatacaa tgtttatcat tgctgtaatt aatggtctaa acctgtctgc gtaccatatt
     3601 ccagcagcat ctttgtataa cccaattaac tgatcaattt catataagaa aaaatgaact
     3661 atcataaata taacaaatga aatactcata agattatcac ttcccaccca gataatcatg
     3721 aacggctgaa ataatgtaat aaagcatgca caactaattg ccagaaacca acctataatt
     3781 gttgtaatat cacaaaaatc tatataattt ttttcttgac tttctacaat aagactgtta
     3841 cctatacctg ctatacatga ttcataaatt attgcaaata tactcattat ggcagaaata
     3901 ataaagtaat aattctgata aatcgcaagt actgaaagac ctaagaaaga tgaaataata
     3961 attgaatctg aagatcgtaa tattgtaccg cctaccttgt ttgtaactaa tccttttact
     4021 ttttttataa tatcgtcaat agtttctttc tctaactcac caacaggagt ataatcagga
     4081 tacatctttt gagaaacaac agcacacatt aagttaagaa ctatttgtcc caaaatagaa
     4141 gccaataaat acaaatagta attttttaag aaaatcagaa catatgcctg cattacaaat
     4201 tggaatgtaa aagtaattag catagacacg ttaattacat catttctttg atgtgcatat
     4261 attagactct ttctatatga aaataaccaa tacgacaaaa cagtatttat caaatacatt
     4321 aaatacaaaa ctgtcatatt taaatttcca ggaatcgaac ctttaactaa aaatctcaaa
     4381 aaaggaatgc ataacaatcc taatgtaaac actatccatc caataattga aaagtacttt
     4441 ttatatgcgt tcagtaaagc acaaatctct tttctattgt cttctgctat aggtttatac
     4501 atacttacag ttagtgcagc acctattccc aattccgcta aatttaacat ttgaaatata
     4561 gatgtgaaca ggttgttcaa tccagcatac tccattccca tctgataaat cataagtgta
     4621 cgcataaaaa agggaatgat aatctgatat aacttaaaaa ttgttccagt aattatattc
     4681 cttttagcat tttgtttacg attaattatc atatcatatg gctccaaact ttctattttt
     4741 tattgttacc taatactata taatttctaa aatcttgaaa tgtaataggt ttcttctagc
     4801 tctttgatta attacgctaa ttttcatgtt tggacaacca caaaaaacta tacattttca
     4861 atcaaagcaa cccattgttt tgtaatttct ttcaaattaa atttttgtac attattatat
     4921 gcgttcagtg acattctcat tgctaaatca gtattcttag taaacattat catgctctta
     4981 gctaattggt ctatattctt atcttcaacc aacatcccat taaaattatg atgtaccaaa
     5041 tctctcggac cagttttaca atcataagaa ataactggta atccataaga ctgtgcttct
     5101 aatataacca taggaaatcc ttcataaaca gaactaagca cataacaaga tgcagattta
     5161 taatattcct ccacatggtc tgaatgccct gctatagtta ctctttgcag atttaaatct
     5221 tttatctgct ggcgaagatc tttttctaat tcaccttttc ctacaatgat aagatcccaa
     5281 tcatctactt ttttttctac aattttccaa gcacttatca tgtcagcaaa atttttctct
     5341 tccactaatc gccctactgc aagaaatctc tttttatcat aatgatattc gtactcgata
     5401 ttagatatac acggatttgg catagttata acaaaatctt ctgataaact atattcatca
     5461 atatgttttt gacgatcttc ttctgtgaga accacaagcc tctttgcata tttttttatc
     5521 aattttttag ccttgaatct cttcttttct ttcagcattt ccattgtcca gtaattaaaa
     5581 tgttcccaag aaatcaattt gcactttgtt cctttaattg cccttgtagt atacaaagac
     5641 aacaaagtat caatatcaat tactatatca aattcatttt tgcatatata cttgtgcaat
     5701 ttccaaaccg gatataaata agttctatat aattttccct ccgttttagg atttaacata
     5761 taatcaacct taatcgtctt atctaaccca aaataaggct ctccactatt ccaaaagctt
     5821 aaaatagtga catcataacc taaatcagac aagctattgg caataatact ccctactctt
     5881 tcagttcccc cagaacgaga aattacacca ctaatgaaac aaattttctt caaagtactt
     5941 ttctccttta taagtgtaaa aattttttca gtgcaagtaa cctgttaaat tttttttgtc
     6001 caattgttga ttttaatcta taaacaaatt tttgtttagg tgttttccaa gatgcattat
     6061 attgatgaat gcttattgta ttactagttt tataaatttt tccagtatca taatccttgg
     6121 cagcaaaata atccgtagga tagatatgca ggccatttat tatttgttcg ctgttatcgc
     6181 gaaccaatcc aatagattca agataatctg taatataata cggactcggt ttcaagttca
     6241 atgtaccatc attttgataa aaacttaatg aatcgtaaat atcccttaaa cctttaataa
     6301 cagaatgtcc ttcttctgca ccaaaaccaa taccgccatt aacccagatt tccccttcaa
     6361 atcccatata ggcatgattt tcacgaagta tatctaacga cttaattagc tcaacatctg
     6421 tatctaaata aaatccacca tgattataaa taatatcaaa tcttgcataa tctggaacaa
     6481 aaccccattt acgttcttta tatgcatcgg ccatataacg gttcttattt aaatcataat
     6541 ttgattcatt ccattcaata atctcataat cagggcaata ctttttccag ctttctatgc
     6601 actttctatc ttttttcgga agtggatttc ccccgaacca acagtaatgt atcttcttag
     6661 gaatcataat atctctcctt ttgtattttt ttcactataa taatgctctt tccttttcac
     6721 aacttcaggc atggctaaaa tcatataaat cagtggcccc gttgtttcac ccctaagtgt
     6781 tgtgttatac acaaaaaaga ataccgacat aattgcaata actttaacaa gacttgcatc
     6841 tttatccttc ataaaagatc tttttgcatt gaaaaatgtc tttattataa aaaataggaa
     6901 tatcgaaact cctaatattc caacttctat aaataaccaa atatgatgaa aatactgata
     6961 atgaagatta ccaaacgatt tataaaactc actgacaaaa aaattggtaa actctgcatt
     7021 gccaatgcct actcccatta ggactaatct aaaattatta ttaaatattt catctactac
     7081 tctagagata ccagttattc gatttaaatc accaacacca tcatatccag aatctcttga
     7141 cgcatattct aaaagacctt gaattgtgaa attatcagca tagctttgtc cattatcgtt
     7201 caatgtaata aatattgtta taaaaaagga taatactatc gacacaagta ttacgcatga
     7261 taatatcttg atcactactt taaaatcaac ttttaaagtg aatactattg caacaaatat
     7321 tataaataat tcaggaataa aaactttcaa ttcagctaat gcagacataa aaagtgctgc
     7381 acaaacacat aaaataaaat ggatgaaatt tttttctccc ttgaaatatc cgattgtaac
     7441 aacagtaact gtcacacaca aaattaaatt caatggcata ttacaacctg aataattcca
     7501 aaaaactcca cctatcatat ctcctacaat tgttccagtt ggataggtga ccatgaatct
     7561 ttcaattaaa caaagtggca gtgaaatcca gaataatttt tcaattatag cgaatacttt
     7621 atagtaatct ttaattgtta aatatgttgc acaatttata tatactatga acatacgagt
     7681 gttatttcgt atcccccaga taatcaatcc tatattttct aaattaataa ctgagctaca
     7741 aatagaaact agtaaaaaca aaactatcag catctcattt ttgctagcat atattccttt
     7801 tctgcgtcta aagctaagtg catttaataa cacaaagata ttaattatat ctcccaaata
     7861 taaaattgct cttggggcgt taaaagtata tacaagaact atggagattg caaaaaatgc
     7921 caacgtgaac aatgtccaat ctgctcctga ccatcttttt attgaaatac gcatcgttat
     7981 tcaccttctt tcgctaaaaa ttattctaaa aatacttttg ttaaattaac ataccctatt
     8041 atttttgccg gtacacctgc aagaattgca ccattctcta gacaatcttt gataacaata
     8101 gctcctgccg caacaactac attgttagct atttttacat taccaataat ctttgcaccc
     8161 acgcatacac gtacattatt tccaattaca ggacacttag gatcgattcc atcatttcca
     8221 atacagttat tcccatataa gtaacaattt tttcctatta tggcgttacc attaataaca
     8281 attccttgtg tatggtaaaa tcttacacct tcatcaaata cattttcacc acactctata
     8341 ccacattttc ttcccaaact attcattctt ctgcaagaca caatatacat aatcgcataa
     8401 atgatatttt tctttctctt tgaataataa taagatgtaa ttctcattcg acgagtatac
     8461 cgccaagcgt tgtagtccgg atgtgatttc attattttta gtaattttgt gtgttgtcct
     8521 ttagattcta tatatagatt cttttccata cgaagaaccg cttttaaata ttctttactg
     8581 ctaatttcca ttcatatctc ctattaattc aatttatact taacaatttt attcggattt
     8641 cttgcaacaa gagcatcatt caatgctact gaatctacaa cgatggatat gttatcttca
     8701 tcgttgattc caccggatac aatattactt ataaaaatcg taacattttt tccaaaagaa
     8761 gggatgtccg tgatgtataa tgcccatttt ccgatatttc cagttattta aacctaacga
     8821 atttttacaa tagtacaagt atcacaatca ttaatatata actggaatat aaatctccaa
     8881 aaattcacta tagtacagtt ttttatgatt aaaatctcct atttctaccc attccgctta
     8941 aatatgctaa tgttttaacc ccaataatgg attggtttag taaaaaatag ttaaatattc
     9001 gttgtttaat tggattttgt ttatatgggt atgagtgaat acaggcaatc aactcatcgt
     9061 tcataagtat cttagacaaa taggagttta aatcaaattc tttattaaaa ctagcatatc
     9121 taactgcctt ttgaatacaa gtacgacagc gtcccaacaa aagtctcctt gttttgttta
     9181 caaatatctc attttctaat atatagctta aatcgccttc aattttttta actaattcaa
     9241 tattacaatc gaactcatta tctctaaaat tatgtgtcaa tgaattatta ttattacatc
     9301 tataataata gatacaatct ttaataaaac ttgttatttt tgaatgttgc aaatatgaaa
     9361 tatggaatat gatatcttca gatatataat ccctttctga cggaaacttg atattgtgct
     9421 gttgaattat ctcagatgaa tacagcgcat gccaaactga cattggcaat ataaaatcga
     9481 ctttataact cggctcagtg ccaatcattc caagcaacac tttttcaatt atagcgttat
     9541 ttgtaaatat cgtactatca tatcttgctg gctttgaaat aatattatta tcatcataat
     9601 attcataata tccagcataa catgtgtctg cattactcct ttttatacca tttaacattg
     9661 cttcaatata attagctgca acaaaatcat cagaatcaat aaaagcaaca tattttcctt
     9721 ttacatgttc aagtcctgta tttcttgcca atcccaagcc agcattattt ttatgaataa
     9781 tacgaatcct tgaatccttt aatgcatagt cttcacatat tttattagat gaatccttag
     9841 atccatcatc cacaattata atatctaggt tcttatatgt ttgattacac actgattcca
     9901 aacaacttcc tacatacttt tcaacattat atacaggtat gattacacta attagatcac
     9961 tcgaattcat ccttctatcc tttcactcac gttttctcaa ttagtcaatg acggcatcaa
    10021 cgattttctt aaattctctg aaaaaaatag actctgatct tgatgatgtg aatgacatac
    10081 tatcttcttc tagaaaaatt atttccttta aattatttat taaatcaata atatgatcct
    10141 cgtaagtatg ctttcccttg gaataatgaa aatatacttt tgtattacac aatattgcaa
    10201 ttttatttct taatatgatt atttcactca ttcattactg ccacatatac acaacttata
    10261 accaccccct gcaaagttta gggtaagtta tcagataata tcttcctctt catcatccag
    10321 aatacaaaat ctatttattt atagaaatat cattaatgtt tttatataat gtaccgtgct
    10381 tgtactcttg ctctattaca agcactaaaa cactactatt catttgaatt cttacacgga
    10441 taaaaattta catcgtctat ttcaatattt tttctctcta ttttattcac ttaataagtt
    10501 cattacataa tcgaaacatt ttttattttc cttgtcatca ctccttgctc cctttttgat
    10561 acagatttaa aattctatca aagaaatttc catcgttaaa tttcgttatt gccaaatcct
    10621 tcgaacaacg tgaaaatttt acgtatttat ctttatcatt gatttttagt attgcagatg
    10681 tcaacgctga tacgtcacca ggttgaaaca aatatccatt ttctccatca cgtactgctg
    10741 aagaaatatc tcctacatct gtagcaatta caggcattcc ataagaaatc gcctctagaa
    10801 tagatatagg caatccctcg ttataggacg gtaaaatcat cacatttgat cttctatagc
    10861 actcctcctt tttttctccc acaacccaac ctgtaaattc aaaatacgat tgcaaattat
    10921 attcttctat caattctttg agcgatattt cttcatcacc tgctccagca atctcaaaaa
    10981 taaacttttt ttctggatat tgttctgcaa tgtttttaac tgcttctacc aaatcgtgta
    11041 caccttttcg ctttatcaaa actcccataa acagaaatcg gcacattttt gaattccact
    11101 ttatggtata ttctggaact acaatagaat tttctacaac aacagtttta caatttggct
    11161 caatttcttt aattatcttc ttccattttt ctccaagtac aatcgtggaa tcagactctc
    11221 ttaacagcaa gcgaatctga ttttgttttt ttacagaaac actatcatac cattttttaa
    11281 attccgatcc atgaagatgg atgattacag gaatatttaa taatctaaac cacttattca
    11341 gcacatattt cctactaaaa ctccctctgt acgacatgtg catatgaata atattaggtt
    11401 tactcaataa agagatacct ataattttag caaatgcata cataaaatat aaagatttaa
    11461 atattgcatt tccaccctta taactcggta taaaagtcat ctcgatattc tttttttccc
    11521 aattaaaatt gagcatttgt gtaattatac ttgtaattcc accttttacc gagctgtcat
    11581 taccaatcat aagtactctt tgcataacgc tttactcctt atatttatat tttttctatt
    11641 aatacctcta tcgaattaat aatcgtttcc gtgttagata catacttgtt aaacatccga
    11701 actcttgttt ctttaacggc atcttctaaa ttttctaatt cataacaagg atagataata
    11761 ttcatctcat caaattgtct aattaactgc agttggtgat catcgacatg ctcaccatac
    11821 ttagccaatc gaggaacagc aatgaccctt ttaccttttt ttacggcccc aattatagca
    11881 cctgtacctc catgagtaat caccatttct gctttttgca tagtttcagt aaactcatcc
    11941 ctatttagaa atgctttata ggaataattt agtggtttat aatcactata accactctgt
    12001 gcaaatgtac tttcgattat tactcctttt tcaattaaat catcaatagc ttttaacaat
    12061 ctatcaaatt gaaatttttg tgaacctaat gttataaata tcattttttt ctcctattat
    12121 ttaatatatc ccacccaaat aaatagcatt aggataaaat tgtagcatag tttcccactg
    12181 aacataaaat tgatctgcaa aatgatacat caattttcct gtctgagtag ggctggttac
    12241 ttttgcaaac gattcaatat aaatcagttt ttttcccatc atttttgtta ttaagcagat
    12301 agggatcata gctaaaacac ctgtacaaat cacgagatcc ggtttttcct ttatatatat
    12361 aataattgat ttgaataaat taataagtat agtacacaaa aaaaactttt cttttctatt
    12421 tacttgtctc atgtagtacg ttttttcgcc ttttgactca gctgaatatt ctgtctgttc
    12481 tgttataaca aaactctcat acttctccat cagtggtttt aacatcatta actgttcata
    12541 atgcccccca gaggaagccg caaaacatat ctttttgttc atattaacct ctctatcagt
    12601 cacgctgaaa aatatctcta gtgtaaactt tttctttaat atcatccaag caggtatcat
    12661 atcgattggc aataatagaa tcacacatcg ccttaaactg ctctaaatcg ttgataacct
    12721 tacttccgaa aaaagtctct ccatctttca gtgcaggctc ataaatcacc acagtcgcac
    12781 ctttagcttt tacgcgcttc ataactccct ggattgaact ctgacgaaaa ttatcactgt
    12841 tgctcttcat ggtcagccgg tatataccga ttaaaactgg attttccctg ttgacatcat
    12901 actgattata ttcagcgtag ttgtaatagc ccgccatctg aagaacacga tctgcgatga
    12961 aatccttacg ggtacgatta gattcaacga tagcctcaat caaatttcca ggaacatctg
    13021 catagtttgc caacaactgc ttggtatctt ttggcaagca ataacctcca tatccaaagg
    13081 atggattgtt gtagtgagtt ccaatacgag gatcgagaca aacaccattg attatctgct
    13141 gagtattcag ccccttcatt tcagcataag tgtctaattc attgaaatag ctgactcgca
    13201 gtgctaaata ggtatttgca aacagcttta ctgcttcggc ttcagtgaat cccataaaaa
    13261 gagtatccac gttctcctta attgcacttt tctgcagaag tgttgcaaaa acatgagcag
    13321 catttaacaa gcgctcatca gtcatatcag taccaacaat aatacgagat ggatacagat
    13381 tatcatataa agccttgctc tcgcgcagaa actctggact aaaaataatg ttcttactcc
    13441 ccgttgtctc acggactgat tcagtgtagc caacaggaat tgtagacttg atgaccatga
    13501 tggtatcagg attcacgtcc atcacaacct caataactga ctcaacagca gaagtatcga
    13561 aatgctgagt acgactgtca tagttagtcg gtgtagcaat aacaacgaaa tctgcggatt
    13621 tataagcgct ccttgcatcc aaagtagcag ttaagtcaag ttctttttct gtaagatact
    13681 tttcaatata ttcatcctga attggagact tccgtttatt aatcagttca atcttttcag
    13741 ggataatgtc taccgcggtt acctggtgat gctgcgccaa tagtgtggcg atactcaaac
    13801 caacataacc ggtgccggct actgcgatgt tgtacttttt cttcacaata tctcctcttt
    13861 cctctcttaa gtatggagaa tgttactcct acggctattc atcatgtcaa aataacacag
    13921 cttagaatgt tgataaaata attttccaga atgtgataaa atctctttca tttataaacc
    13981 acacatctaa ttttatctat tctccacaag acatgtagag tattctttaa taacaagata
    14041 cgaccttact aaatacttca aaaaattatc atatttaatt cataaatata aatcttcatt
    14101 ttaaatgtat gcccaaaaat ttatctgtaa tgcgtcatca aaatctagat tccaaatctt
    14161 tatcaatttt tatccactca ttctaccact ttagtaatat tttctattta taacactttc
    14221 gtcctacatt gatccccccc tctgaagtac agtttttact gtcttaaata aaattttaaa
    14281 atctaacccc atactccaat tttttatata ttccgtgtca agttttgcta cttcttcaaa
    14341 atcagtaata tcacttctac cacttacctg ccacattcca gtaattcctg gcttaatagc
    14401 aattcttgca cgatgatgat aatcatattc ttcatactct gatttaaggc atggtcgaaa
    14461 tcctataagg ctcatctttc ctgttagaac gttgaaaaat tgagggaatt catctaaaga
    14521 cgtggatcta ataaattgac cgattcctgt cttttttgtt ccatctggaa gtattttatt
    14581 tccgataatt cttggatcaa actccatctt aaacataaga ttattgctca tcttattttc
    14641 tttcattaat tctacttttc tttcttctgc atccatatac atacttctaa acttatacat
    14701 cttgaacggt ttaccattct gacctatacg ttcttgtgca aagaaaattg ggcctggtga
    14761 attaatataa ataagtggag caataaagat aaaaataatt cccgttgcaa tacatccaac
    14821 aatacctgca agaatatcaa ttgttcgttt tataaatgcc tgttgagttg tcataacatt
    14881 gatacttgtt gtaagtactg tatattctcc tatacgacca atagattgtt ttcccaaagc
    14941 actatctgat acttttgcaa gattcaaatg tacagtaagg cccatttcag agcatcgttc
    15001 aataaattct ttcatacacg aagtactttt attcaaaata ataaagactt catctaccca
    15061 tccctgacat aagtaatccg ctgcattttt ggaatcagaa acaactgtca ctccctcaac
    15121 atcttcacca atcatgcttt tatctatgat aatgacacca tttattttat acattttata
    15181 gttatgctct ttcacattac gaataactac ttcagcaata ctactagatg taactataat
    15241 aagtgatttg ttcccctcat ttttcatttt atgtttcaag taatgtttcc ataagaggcg
    15301 agttatatat gtaattacaa cgtataaacc tcccatcaag aaaagaacga ctctagaata
    15361 atcatttcca ccctgaacac taatgagata caaacttcct aacagcacca acataatcgc
    15421 ttgctttaca gaagaagcaa attctatata gtaccctctt tttaatacac ctctatatgc
    15481 ttcaaacatg aaaataacta aaagatctgc cagttcaatg aagactgcca tgttttgata
    15541 cattggaatc acataaggat tccaatctac ctggcgtaag acatacgata gataaaaagc
    15601 aagctggata cacaataaat ctaaaataat aaaatcaata tgtttaaccc atccccttga
    15661 acttttcttg tacattcctt tttactcccc tctttttaat aaaataaatt gtattacttg
    15721 ttttctctcc taaatatctt tctgaaggat tattgactcg acaaattggc ttgtggatat
    15781 tcttatatat agaacatccg taagccaact taaaactcct taacaaaatt tttttactca
    15841 tattgtagat caaaacaagt atccaagaaa tcatatttta tttctttttt ctgcttactc
    15901 aacaacagct aaaagaaaaa tcatcataaa caaattcaac taagccaacg atccccttgt
    15961 gaaatcaagt tttttcttga tttacgaata aagagctaaa ataaaccaaa cttcttcttt
    16021 tttacctctt catagactgg ataactgatt tcatccccgt tgatcagatc ctttgcgact
    16081 tgtttcatct gtactacttt ttccttacca aagtcctttg caatctgctc atagcactct
    16141 tttaagtaaa aggtgcgctt agagacccca tgggcatcag aagcagccat ctgcacgaga
    16201 ttatgtttga ccatcgtttt ggctgttttc tggatgtctt tgccaaatac cccaacataa
    16261 cttggcgcag tgagttgggc caaacatccc atatctagga acggaagcaa atgatttggg
    16321 tcttcgcgaa aatgcacgtt gcgttctgga tggacgatta ctggtgtctt tcctagttct
    16381 aacaactcaa aaaaaagccg ttctgcatat aacggcactt ccagtgtcgg aaattcgatc
    16441 agaagatatg tatcatctaa atctgtaaat aatatttcat ctcggtggat gtcttcgatg
    16501 agcgttccgg taatacgtac ttcttgtcct tccaataacg tcaaaggcaa ctgtcttttc
    16561 tctaattcgg cttgtaacga agcgactaga gaaatgactt gtgatttttc attgctgtat
    16621 tttccattat tgtggtgtgg tgtgcataaa atatgcgtga tgccttgctg aatcgctttt
    16681 tcagccattg caatacttgc ttctaagttt tctgccccgt catcgattcc tggtaggata
    16741 tggcaatgta gatcgatcat ttctcttgtc tcctctcttc ttattcctta atttccgtag
    16801 taataaccag catctttgct atgttctgct ccgttgtaca caacacctaa gactcgtgct
    16861 tgtaccatct ccagcagttc ttttgcttta gtcaaggatt ctttacgtga catattttca
    16921 cgtacgacca ataaagtgcc atccgttttt aaagacatga tctgtgcatc tgttacggct
    16981 actactggtg gcatatcgaa tatcaccacg tcaaataact gtcttgcttc ggataggatc
    17041 tgatccattc ttggcgagct taacaattct gatgggttgg gtggcttagg tccactaggc
    17101 aaaatcgaca agttctcgac tggcgttcgt tggatcacat ctgctacact tcctgatgaa
    17161 ctaagtgctg tacttaatcc actggcattg ttcagctgga atgtcttata gacgacgggt
    17221 ttacgtaaat ctgcatcgac tagtagaact cgttgacctg atttagcaaa aacgactgca
    17281 atgtttgctg cagtggtgga tttcccttct ccaggacctg atgaagtcac gacaatcgtt
    17341 ttgatttgct gaccagctgc ggaggcaaac tggatattcg tccggatcgt acgatattgt
    17401 tcggcgattg gtgaagatgg gtttgttaat gtgatcaaac tgactgcatg agtttgtgct
    17461 gctttttgtt tctgtgttcg tgccattttt cttcctccta gactcttgag cggcttctgc
    17521 gtgatggggc tgttttatcg tttgtagctt ttggtcgtgc aggagctgtt ccttttttac
    17581 ggataccagc gttcaattct ttcgctgaca tttctggaac tgttcctaag attgggaatc
    17641 ctaatgtatc tgtcacatat ttttcatctt tcactgtccg atcgagtaat tccaataaga
    17701 atgccagacc tacacctacc atcattccta acattaagcc agtcattaaa ttcaatttat
    17761 tatttggcga aacaggtgtc gtattggcaa ctgcacctga aatgatcgag attttatcaa
    17821 cattcatcac atcttttgcg ttctcttgga aaacttgtga agttgtgtta gcgatctgtt
    17881 gagcagccac tgcattcgta cttattgcct gaatcgagaa catttgtgaa ttttctgcct
    17941 gattaactga gatggcatct ttgatttgtt cagcagtcat tttcacattg tcttctgttt
    18001 ctaaacgatc tttgacttca ttgagcacta aatcactgac gatcatatct ttatacgtat
    18061 tgatcatttg caggttcgta ttgacatcat tgacatttgc agtgtctgat tgtggcagtg
    18121 tcacgatcaa ttgtgcttgt gaactgtatt ttggtgtcaa gatgaaaaat gttacgattc
    18181 ctgagatggc caagccagca aacattgaga tgatgattat taccaagtgt ttgcgtaatg
    18241 tttcaaaaat ttctttcaag ctgattgtct cttccatttt ttctccactt tcctatttat
    18301 tctctagatt catttgatct tttaattctt ttttcacacg atcaagttct tgatcactga
    18361 ctttttgata ggagatatta tcttgcatga agccttctcc ttgcagctga tcttgcttaa
    18421 tcgtaccaaa tgcctcccga taatctaaag caattttttt catttcatca aagttcatgt
    18481 ctgttttcat attcgactct agagcattca aaacggattg atagttgctg acaccgttta
    18541 gactcaatac ttttttcgct acgccttcta cgatctttct ttggcgccct tgtctaccgt
    18601 aatcaccatt tgggtcttca taacgcatac gagaataaga taatgcctga tccccgttca
    18661 atgtaatttt accgattgga aagtcatagc catcttgtga gaaagtgagg tcattattga
    18721 cttcgatacc accaactgca tcaacgagtt cctttagtcc tttcatattg atagagacat
    18781 agtgatcgat tgggatgtct acatattttt gtacggtatc catcgccatg gcagctccgc
    18841 cgaatgcgta agcgtggttg atcttgtctt ttgtgtcacg acctacgatg tcgacatacg
    18901 tatctcgagg aatgctgacg atcgttgtct gtttgtcttc aggactgact gtggcaacca
    18961 tcatcgtatc tgatcttcct tgatcgaccc gacctaaatc tccagtatca atccccatca
    19021 atagaacaga gaaagattct tgtttgtcca gatcaactgg tttcgttcgt tctccttggg
    19081 ttcgttccac tgattcgtaa gttttctcaa tagaatgtga gagatccaga tataattttg
    19141 ctcctactcc tacaattgct aatactaata cgataagaac tgctaaaata atcaaaaata
    19201 tttttttccc tcttgatttt cttcttcgtc ttgccatagt ttcctccgtt tgctaacctt
    19261 gcttgaatca acgttttaac tgtcaatagc ttatattgct atagcccatt tgctgagcaa
    19321 cagtttgtgc ttttgttgcg tatgcggctc ttattttttc attccggatc tgctctattt
    19381 gactgagcgc cgtcaaatat tgatcgtaag tagcggtagc tgttacttga ccgtctttca
    19441 gcatcgtatc gaatagctga tctagttgcg tgacttgtgc aatttgggta tcagcgaatc
    19501 ctagatattg cataacgact gttttccaag cactatcctt aaaaaagctc atattttcac
    19561 gtacatgggc gacatctgca cttgccaact tttctttgat gatgacatca tccacagctt
    19621 gctgccagtt tgatacgttt ttagtaaata atttattgac agccgtctgg atcttcagtt
    19681 ttgattctgc atcctctaac tgcgttaaga ctgctttctt ttcttcttgg atcgcagcag
    19741 cttctttagg taattctgat tccttgatgt cataatcatc tgccgaaagt ttgatagaag
    19801 atagtttatg tgacaaattt gaaactgttt cttctgttat ttcaggattt aggaaaattt
    19861 tttcttttgt actgtacagc ttatctactt cttttgataa agaggtcacg gtgtcttttt
    19921 gattggtgat ggcagattct gcgtaattga tccgttgatg atattgccgc tgattattga
    19981 gatggtatcc aaacaagcaa atcacaatag cgcctgtgcc taccgccaca gtagccaata
    20041 acttgacgaa cggcttttcc atagattcac tcctaaatat tgatgataga taagtaaaga
    20101 tgtgattcat tcacatcaga atgagcgctt tttattttaa aagcataatt aaactaatat
    20161 attcatagaa atatttataa acaggttttc cctatataat cataccacat acagtttttt
    20221 tgactaggga aattcctaat ttaaaagtaa ataaaacagt aacaagatta taattaatcg
    20281 ttttcatttt tatttcctca cttttcatga gcgttttgaa aattcgaaca aagaataaaa
    20341 taacaaaaat tattaaaata gaattaataa cagctattta taacaaaaaa aacagagaca
    20401 cagcacgttt cgtgcatgct ctctgttttt caaacaaaag actattttgt gatgatttga
    20461 tccaagcttg ctaatgacaa agccatggca gctatttgac ttagttgtgt tagtcggttc
    20521 ttacgtactg ctggttcatc agccatgacc atcgtttgat caaaataatt ttcgatcagt
    20581 ggacgaagag cgacaagctg gtcgtagttt tcgtggatcg tttggtcagc aaaacttgct
    20641 ttcattgctt ctactgcttt gtgtaattct ttctctgcgt cgttttcgaa cagctcaggg
    20701 tctacttctg attgtttttc aagctgcgct tttttcgcta agttcacgac acgtgtcaaa
    20761 gcttccattg aaggtttgaa gtcttcatct gcaagatgtt gtttgaacaa ttgtgctgct
    20821 gcaaatactt ttgtcagatc tttttgttcc gcattcaaaa cagcatcgat gacatcatga
    20881 cgaatattct tcgttgtcaa taattggcgc agacggcctt tgataaagtc gatcacttgt
    20941 tgttgccctt ctgataaacc aatgccgaaa cgatccgtat ctttactgat aacatcgcta
    21001 atcgtttctt gcagaacaga caaaggaaag gcccattttt tcgattcgat gatccgaacg
    21061 acaccgtatg cttggcgacg taaggcataa ggatcgtttg acccgcttgg aatcatccca
    21121 actgcaaaga aagaaaagat gctatctaat ttatctgcaa tcgctaaaac agaacctact
    21181 gtagactgag gtagctctcc ttcactggat ataggcatgt aatgctcacg aatcgctgtc
    21241 gctacagcag gtttctcgcc tttcagaaga gcatattttt cgcccatgat cccttgtagt
    21301 tcaggaaatt cccctaccat gttggttact agatcaaatt tatagatttc agcagctcgt
    21361 tgcaaatcca tcaattcttc ctcagatagt cctacttgtt cgccaatgat acgggcaatg
    21421 acttgtaccc gttgcatttt ctcatagata ctaccgattt tttcatggaa agtaacagtt
    21481 tttagttttt caacgtattg gtcgattgaa gctttcttgt cttcattata aaagaattcc
    21541 gcatcttcta aacgagccgt caatactttt tgattgcctc gaaccacatc ttccaatttt
    21601 acccgatcac cattacgagc agaaataaaa tgaggaagca gcataccttg atcattccgt
    21661 acctcgaaat aacgttgatg ttctttcata gaagtgacta gtacttcttc aggaacagaa
    21721 agatattttt cttcgaagtc gccagaaaag acagttggat attcgactaa attgttgact
    21781 tcttctagta aatcttcgtc tagatcaata acccagtgat ttttttctgc taattcgttt
    21841 gcttgtgtaa cgatcatttc ttgtcttttt tgcggagacg caatgacgaa ttgttcattc
    21901 aatttttctt catattcttt tgcatgcgca aatgtcacat cttcgcctaa gaaacgatga
    21961 cctcgagagg ctctgcctgt tttgacatcc aagatttcga atgggattac ttcgtcatct
    22021 aacaatgcca cgatccagtg aatagggcgg atatattcaa aatcgtattc tgcccaatgc
    22081 atcgttacag ggaaagtcaa acttttgatc acccctgcta agcctgtcaa tacttctttt
    22141 gcttccttac catgagtgta tttcgttaca tagacatatt ccacaccttt taattctcta
    22201 aaagtgatag cgtctgtcgt cagaccttgt ccgcggacaa atccttccgc tgctttcgtc
    22261 cagtttccat ctgcgtccaa agcaattttt ttggctggtc ctttgacttc ttcttcactg
    22321 tccgcttgtc gttctggaat atttgttact ttgattgcta aacggcgcgg tgtggaaaat
    22381 gtttcgatcg tatcataagt caattggttt tcatctaaaa attttgctgt tttttcttct
    22441 aattgtttca tgcttggtgt gacaacatgg gcaggcattt cttccagccc gatttcaagt
    22501 aataagtctt ttgccatctt attcagcctc cttcacggtt tctggatttg ctgtgttttt
    22561 attcaacaaa gggaatccta atttttcgcg ttctgccaca aagattttgg ctacagcacg
    22621 agccatgttg cggatgcgag aaagataacc ggcacgctct gttacggata ctgcaccgcg
    22681 ggcgtctaat aagttgaatg tatggctaca tttcaagata taatcatacg ccggatgaac
    22741 aagattttca tcgatacagc gtttagcttc tttttcaaaa cgatcaaagt tgcttagtag
    22801 caagtcttgg tcgcttactt caaaagaata tttggaatgt tcatattctg gttgtttgaa
    22861 gatctcgcca tatttcacgc catcagccca ttctaaatca tagacacttt caacttcttg
    22921 gatataagaa gcaagacgtt ctaatccata agtgatctca gaagttactg gtttacaagg
    22981 cagtccacca acttgctgga agtacgtgaa ttgtgtgatt tccattccgt caagccatac
    23041 ttcccaaccc acaccggcac agcccatgga tgggttctcc cagttgtctt caacaaaacg
    23101 gatgtcgtgt tctaatggat cgattcctaa aaggcgcaag ctttctaaat aaagctcttg
    23161 aatattctca ggtgaaggtt tcatcaccac ttggaattga tgatgctgat acaaacggtt
    23221 tgggttttca ccataacgtc catcagctgg tcggcgagat ggctctacgt aagcagcatt
    23281 ccatggttct ggtccgattg cccgtaaaaa ggtatatggg ctcatcgtac ctgctccttt
    23341 ttctgtgtca taagcttgca tcagcatgca gccgtttgat gaccaaaatt tttgtaatgt
    23401 taaaatcata tcttggacgg tcaatttttt actcatctgt tttgcccctt tcaattttaa
    23461 agcgttgctg tcaaataaga atacaggaaa gaaaacgaca aaaaatccct atgtctgatt
    23521 acagacatag ggacgaataa ttcgcggttc caccctactt ccgaataaag attcggcagc
    23581 ttcatttatc gtactcgcaa gtgcctcttc aaaaatcgtt tgggtccggc tcccactctc
    23641 ccgaactcgc taaaccacgt gttttttact gatcttggtc aatgtacgta ttcattttgc
    23701 agttttcttg tttctataat agatcctatc actgaacgat ctatttaatc tatggttaat
    23761 aatagacgga actccctgtg tttgtcaaat ggttttgatt ttttgttgta tgttttattt
    23821 actattcttc tttttcaggt gtctcttttt ctttttcaga catgtctttc tctgacgtct
    23881 ttaatacgtg tgcccaagac ttcatttgat tgatgaactt tttgcttttc aaatggatac
    23941 cgacatattc atcatacagc tggtcgatga gttcacggat tgcttgtttg gtttcttctt
    24001 tcagatggat tccactaatt ttatcataag aaatagctga aaacatccga acgaaataaa
    24061 cagctcgagg atctgcatga taacggtgat cgtccatcga ccaatgtctt tcgcatatca
    24121 caccaccata tttggaagaa tagtcaaatt ttccttttgt ttccccgcat acgacgcagt
    24181 gtgtccagat tggtgcaatt ccgaagcgtt gcagtatttg gacttcaaaa atattcgtga
    24241 tgatttctgc atcgtctcct tggtccatcc gttgcagtgc ttgttgcgta aactggaaca
    24301 aatgcgggtc gtactgatga tcttcgattg ccgcatctac tagattcaat aaatatgtgc
    24361 catagccgct caaaaagatg tcttcttgga tgtgtcgaaa cgcatggaca tctttgacac
    24421 tgcttaaaaa tgacaaacct tcacttcgaa aattcccgat ataaactgct tcagtaaaag
    24481 ggagcaaagc cggagctaag ggctgatttt gccgatggat ctctttgata taaaacatca
    24541 ttttgccaga agattctgta aagattttga ctaatttatc tttttctttg taattacggc
    24601 tagataaaat caagcctttt gattctgcaa gctggctcat attctccctc ctaaaaaata
    24661 aatctggaaa agcagattct gccgatccag atcatttatg ttgcgatctt ccgcagcttt
    24721 tctcaacacg cggattttta ttcagtttat ttctatacct aatttacaag aagctcagaa
    24781 tatcagtatt cgtcttttcg gtagccgaag tcttgcagat agactttttt gtctcgccag
    24841 tctttttgaa ctttgaccca aagttctaga aagactttgt ctcctaaaag attttcgata
    24901 tcttttcttg ctttcgttcc tacttgcttc agcatttttc cgcctttgcc gataatgatc
    24961 cctttttggc tatctctttc gacaataatc gtagcctgga tatggatttt atcattctcg
    25021 tttcgcttca tcgaatcaac aacgactgcg acagaatgag gcacttcgtc tcgtgttaaa
    25081 aacaagactt tctcacggat caattcagaa acgatgaagt attcaggatg atcagtcact
    25141 tgatcatctg gaaaatattg tgggccctct ggcatttcac tgactaatac atccatcaaa
    25201 cgttcgacgt tgtttccttc tgtagcagag attggaatca cttgtgcaaa aggcatctgc
    25261 gttgaataat cttcgatgat tcccaacaac tcgtctggat ggattttgtc gattttattg
    25321 ataatcagat aaacaggaga atgcacgttt tttagacgtt caataataaa atcgtctccc
    25381 cgaccgcgtt tttgatcagc actaatcata aataagaccg cgtccacttc tttcaacgca
    25441 ctgtaagctg cttctaccat aaaatctcct aaacgatgct ttggtttatg gattcctggt
    25501 gtatcaataa aaatcaactg agcttctggt gtagtgtata ctccttggat tttatttcta
    25561 gttgtctgtg ccttgtcact catgatggca attttttgac ccacgattcg attcaataat
    25621 gtggatttcc ctacatttgg gcggccgacg attgcgacaa accctgattt atgttctggc
    25681 atatatgttc tcctttttaa ttaaacaaca aatgatatat tttagggaca aataaaatca
    25741 acccaacgat gacggtaaaa caagcggtca ctaaaactgc tccagctgcc atatctttga
    25801 tttttttccc aatcggatga aaatgaaaat ccgtaaacat gtccacgaca ttttcaaaaa
    25861 cagtattgat gatctctact atccatacga gaaaaacagc taaaagcagc cataaccatt
    25921 ctatccgatc aagttggaaa atcacgccca taaacaaagc gaggattccg aacgcaacat
    25981 gtttcctcat gttgcgttct tcctcaaaaa cagttttgac tccttggacg gcaaattcca
    26041 cggacatcag gaaatgtttg tttttctcta cgtttttatc ttttaagtcc ataggcatct
    26101 aagatctctt tctgtaaacc aaacatttct ttctcatcct ctggtgtcat atggtcatac
    26161 ccgttgatat gcaagaatcc atgaaccgct aaaaagccaa gttcccgatc atacgaatgg
    26221 ccgtaagctt ctgcttgctc tgcagcacgt tcagtagaga tcatgatgtc tcccagtaca
    26281 cgaggcaatg gattctctcc atcttcaaaa atcactggga tttcgtcttc gccctcttct
    26341 tccaaggcaa aactgatgac gtctgtcggt gcatcttttc cacggtaatc acgattgatt
    26401 acttggattg ctgcattgtc catgaaagta acagacattt ctgtttcttc tggcaactct
    26461 aaatatgatg ctgcaaattg cagcaagtcg tcgatttctt tcattttctc ttctgagact
    26521 tggtttgttt catccatgaa ggtaatatcc attatacatc gcttctttct attcttcttg
    26581 ctattcttct tgttcttctt ttatcttctc aacttccgat ttcattttag gatatttgat
    26641 ccgagaatgg aaggtactgc ttaaaccgct gatcaatgat ttttctactt tacggatttc
    26701 ttttaacgtc aatccactgt cgtccaattg tccatcggaa atacgctctt caataagatt
    26761 atggacaaaa ctttcgattt tttcgctcgt tggatggtcc attgcccgta ctgccgcttc
    26821 acaactgtca gctatattga cgattcctgc ttcacggctt tgaggttttg gtccaggata
    26881 acggaattgc tcttccgtaa cttccgggtt gcgttccttt gccttaacgt agaaataacg
    26941 catcagcgtg gttccatgat gctgtctaca aatatcgatc accatttgcg gcatattata
    27001 atcttccaat attttggcac catctgtcac atgtccaaag ataatatgtt tactgtcttc
    27061 tggcaataag aaattgtgcg gattttccgc tcctgaaggc aagttctcaa cgaaaaagct
    27121 ggcgtgtttg atcttgccga tatcatgata atagcaagct actcgagtta gtaaagaacg
    27181 tccaccgatt tctgctacag cattagcact tagattggct accatcatgc tatggtgata
    27241 cgtacctggt gcttcttcca gcaactgttt caataaagga tgattgggat tgctgagttc
    27301 atttaatacg atcacactat catcattgac catcaattca atataggggt gcagacctat
    27361 cgtcagcaag aatgaaaaca gtgcacctgt gaatccgcag actagcgtta accaagtcgt
    27421 tgcatcccca aagctcattc cttggtagat aatcaaaatg acatccatca tcacaggaaa
    27481 aataatgacc cacatagcag cggataaccc ttgttctgag atccgtttgc gtctgacgat
    27541 cgttgccatg agaccagaaa atacatagga catcaaaata actgtcagaa agttcgtgcc
    27601 aatcgaatca taaaaaatga aaagtgcgga tactgcttga aaaataccag ccatgatccc
    27661 tgctcttcga ttcaagaaaa agcttaaaac aagtggagca aaagccgcgg ggtaaaacag
    27721 cggaatataa gcagcttgtt ctgtttggaa gagttggaaa aatttcatta gtacgacgct
    27781 tactgacatt gccgtcacgt agaaaagtac gtattttgtt ctttctcctg cattttggaa
    27841 ttgaagtgaa ttataaatca gtacaccgat ttgaagcaaa acagctaaaa ccatggcaat
    27901 gagtgggaaa atagaagtcg tttgattcgt caatcctagt aattccaatt ttttcatcgc
    27961 tgaagcatca atttgatttc cttcgcgaac aataatttct ccttggaaga tcatcactgg
    28021 ttgtacagct tctcgtgcag attgttttaa ttcttctgtc tttttctcat tcaatacatc
    28081 attaactacg atgccttgat ccactaagta gcgaatcatt tgttgctgct ctgttgtgac
    28141 attcaaatat tgaatctgat cttctgcttc ttgtttaaaa gcttccaatt cgctttcacg
    28201 aacttgttta ctcatctgtt cgtcaatgag cttcaaactt tcatccctaa ctgtgtgaat
    28261 ttccgtttca gtcatttcaa atatcgtcga ataaaaattg ttcggcagtt tttggtaaaa
    28321 cgcaacgttt tctgcattca cgttttcaaa atttttcttc agtgtagcaa tccgctcttc
    28381 tgtagtaggt ttcgggatat tttcatcttc cttcgcctta tctaccttgc cattataaga
    28441 tttgttgatg gtatcattcg tcttatcgat caattcgaat aattgcttga tccgattgtt
    28501 ctggtcatct gccagatctt tttgataagt atattctgga gtcactgctt ctgctgccag
    28561 ttttcttctt tgttcggttt cttccgtgtt ctcaatcgtt ttattcgcac ggatactctc
    28621 ttctgctact tggccttctc tgaaatcaat ggccttttgt ttgacactac taaatgtaac
    28681 gccgcagaca atgataaaaa acaagaacag aaggaaaggc aatgctgcct ttccgagttt
    28741 ttcttgtagt ttctgcagtg ttttattcaa catgtgctta tcctcctaag caaagcttat
    28801 tcttgatgaa gatccgcctt ttcataagct ttgatgattt cggcaactac agggtgccga
    28861 acaacgtcac ttgcttcaaa attaacaaaa tcgatttttt tgatttgctt taatgttcgt
    28921 tctgcatgaa caagaccact tgtcgtccca cgaggcaagt ctatctgact tgtatcccca
    28981 ttgacaatca tttttgattg ataaccgaga cgggtcaaga acattttcat ctgagcgact
    29041 gtcgtgtttt gtgcttcgtc caagataacg aatgcatcat ccaatgtccg cccccgcatg
    29101 taagctaaag gtgcgatttc gatcacgcct cgttccatca atcggttcgt atgatccaat
    29161 ccaaaaattt ggtataaagc atcataaaca ggccgcagat aaggatccac tttttctttc
    29221 agatccccgg gtagaaagcc taggttttcc cctgcctcca cagcgggccg cgtcaaaatg
    29281 attttttgca cttcgccttt ttttagggca gcaattgcta atactacggc aagaaacgtt
    29341 ttccctgttc cggctggccc tacaccaaat acgatgtcat gtttggctac cgattcaacg
    29401 tatttctttt gaccgctgtt ttttacccgt ataggttttc cattacggtc tttgacgatc
    29461 tcttcctcat acatctcaac aaaataatct aatgtacctt tttgccccat tttcaatgcc
    29521 gtcacaacat ctggcgtact tacgtggatt cctcgtttga tcaattcctg taatgtccga
    29581 atgactgagg cagccaagga aatctgggat tgctcaccaa tgatctgaat gatttctcca
    29641 cgtgtatgga tggttgtttc cgttgtttcc tcgatcagtt ttatatgctt gtcgtgtgca
    29701 cctaaaagca tgctgacatc atcagcagct gtcaatctaa tctctaaaga actagactct
    29761 tccgtcaaaa atagacatcc cctttttttc gattcattct ttcctatttt accatactca
    29821 gaagaaacta tatagcaaat aagaaaaggt tgtaaaagag tcgcttaacc atacgtacca
    29881 agaaacgtta aaaaatagcc gtttccattc gctaaaggtc tcgttttgat aaaaagaagc
    29941 tgagaatgta agttatatga aagtggagaa caaaatattt cgtttcattc aacaagtatt
    30001 ctctaggtat ttttcctgtt tcaaaaaaag aaaacaaaat agttaaaata ttcttgcatt
    30061 tcaaaaaaaa caggtgtatt attacgtcaa caaataaaca tacagcaaag cgtcgaggaa
    30121 aacagtaggc tattcaacga tttattccca gtgagtcatg taagtgagaa atgacaataa
    30181 atcgaataga cgaacatcat ttccgagtca atgtcgaaaa cgtagatcat tgtggctgcc
    30241 tccattatca ggctagcgga taactttatc aaaaagcgtc cgtgaatgaa gaagcttttt
    30301 taagcgaaaa aaggtggtac cgttctagaa tctagagccc ttttcccaag tggaaaaggg
    30361 ctttttttta ttttaaggtg gtggttttca tggaatctga tattagtggc attactaatt
    30421 gctgcaacgt ttatatcgtc aatcaaaatg ataattattg gaggaaaaat ttatggaaga
    30481 aacaaaaact tattcatgga aacaactatt gatggtcagt tcacttatct tcgggatgtt
    30541 cttcgggtca ggtaatctaa tctttcctgt ccacttaggt caaatggctg gcgcaaactg
    30601 ggtcagtgct ggcgtaggat ttgctatctc aggtgctctt ttcccattac tagctatctt
    30661 agctgtagta gtgacaaaaa gtgatggtct gtatgactta gctaaacctg tcggaaaatg
    30721 gtatgctgcc ttgttcttaa tccttgttca tttgacgatc ggaccatttt tcggtacacc
    30781 acggacagct gctactgctt ttgaaatggc tgctaaacca tttttgcctg aaaaatataa
    30841 ttcattaggt atgtttttat tctctgctct tttcttttta cttgcttatt tccttactgt
    30901 ccatccaaca cggttggtca aatacgtcgg aaagtatcta aactccttgt ttcttgcatt
    30961 attagcaatc atttttgtcg tttctttatt ccatccaatg ggaaatctaa atcaatctgc
    31021 tgcagatact tatcaaacaa acgctttaac aaatggtgtc ctagaaggtt ataacacggt
    31081 tgatgcagta gctttgcttg ccttaagtgt cacttttgtc catgcagtcc gtgaccttgg
    31141 tttcaaagat aaaaaagtca cagaattaac ggcaaaagct ggtagcctga gcgttgcgct
    31201 agaagtcatg atctattttg gacttgttct tctcggtgcg atgagtttga ataagatgtc
    31261 tttatcagaa aatggcggaa ctgcactttc tcagatcact aatttttatt taggtaactt
    31321 cggcgctagc ttcttaggag tgatggtcac attaggtgtc ttcactaccg ctatgggact
    31381 cgttgtttct tttgcgcaag atttccataa actgttccct aaagtcagtt atatgacatg
    31441 gctgcggtta acgactttcg tctcttttgt cgttgcaaat gctggtttag acaatatcat
    31501 ccaatggtct ttaccagtat tgatgctttt gtatccattg tcgcttgcgt tgatcttgct
    31561 ttccttaaca gcaaaatttt tccaaaagac accatttgtc tatcaagtaa cgatgttgtt
    31621 tgctgctgtt cctgccgtat tggatatgct ggcaaattcg cctgctttag tgagtcaaca
    31681 aagagttgta gcaagcatgc tcgaatttta tcatcatcac gttccttttg ctgcattagg
    31741 acttggctgg atggtcccaa cgttacttgg ttacgctggc agcctactgt tttattacgc
    31801 ctatcgccta tcagggtata aacaagaagc aaatgaacta ccagaagaat aaccaaatca
    31861 aacacaattt aacataagaa atattaaaca ggaaaaaacc agctagatga aagaatccta
    31921 ttctttcgtc tagctatttt ttagttctct tttttacgcg cacaaaaaaa ctgcggacaa
    31981 tgattgtccg cagtttaaat gggctctata atatctagtg ttggtgacgc cttctgttgc
    32041 caatactttt tcttttttct aataaacgca aacagacacc ttgaaatcct ttagaataaa
    32101 gtcgacgaaa accattcaaa ggagtgtttc aagatgtcct attcagagtt taccaaagag
    32161 ttactagata ttctagacct aaatcttatc tttcatgaag atgcctttcg caaagagcga
    32221 atcaatgacg aaacatgttt tgtttttgat ggcacattga cctatcaacc agaggaatgc
    32281 ttccattgtc actatcaaaa taagcaaacg atcattaaat ggggctggaa aaaagtatcc
    32341 atcttattga atgatgtcag taactacaag accattctgc ggattaacaa acagcgcttc
    32401 aaatgtaaac actgtggaaa gactttttta gcagaagatt cagttagtga tcgtcgctgc
    32461 tccattgctc gcagagtcaa acaagccatt cttgagctat taagcgaacc tctttctatg
    32521 tctttgatcg cacgtatgaa gcacatttct ccgaccactg tcattcgaat acttcgcagc
    32581 cttcggccta aaaccgtttc tttgaaccag ccgttaccag aagtggtgtg tttcgatgaa
    32641 ttcaaatcgg tgaaaaacgt ctcgggagcc atgagctttg tcatgatgga cggcaagacc
    32701 catcaactga ttgatattgt ggaaaatcgg caactaaatc ctttacgcga ctatttcttg
    32761 cgctacccta gaaaagtccg tgaacaagta cgtctagtgg tttcagattt ctatacaccc
    32821 tatcgcacat tggtgaaaga gtgctttccg aatgcccgaa tcgtcgccga tcgctttcat
    32881 attagccaac acatcggtcg ggcctttacc aaccaccgaa ttcaagtaat gaagaccttt
    32941 aaaaaaaggg atcgtcggtc gaagcactta aagaaatact ggagactact tcaaaagaat
    33001 gcgtgggaat tgaaaggtca gcatcgctac tggcgtccgt catttcgaga tcatctgaca
    33061 gaagcagaga tagtcgatcg gctattatct tatgatgact ccttaaagcg aggctacgaa
    33121 gtctaccagg attttctttc cgctatcaga agacaagatg ttcctgaatt cgtcgcgctc
    33181 ctaaaagaag actacaagga gttgccagag cactaccaac cagtgttcac gaccttcaag
    33241 aaatatcgaa cagaaatcaa acgagcgttg cgagttccct attccaacgg ccctatagaa
    33301 tgtttgaaca accatatcaa agtactaaaa cgaattgcct atggctttag aaactttcaa
    33361 aactaccaag aacgaatctt tttatatcga ggaaaatatt ttaagaaaac taagaacact
    33421 acccaactga ctaaagctag aacaacaaca cggctagaca agatagctgt ctagccgtgt
    33481 gagtatctcg attattctat tgaat
//
LOCUS       DAPBAF010000034        32832 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.034, whole genome shotgun sequence.
ACCESSION   DAPBAF010000034 DAPBAF010000000
VERSION     DAPBAF010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 32832)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32832)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32832
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.034"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(680..753)
                     /locus_tag="RD451_001825"
     tRNA            complement(680..753)
                     /locus_tag="RD451_001825"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(717..719),aa:Ile,seq:cat)
     gene            complement(943..1968)
                     /locus_tag="RD451_001826"
     CDS             complement(943..1968)
                     /locus_tag="RD451_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDT7567084.1"
                     /translation="MKKKITITAMSLLTALFLLPINTFAYTINDEYNLAPNQGDSRLA
                     IPNKIILHETGIDAPARNVAANMKNNYNGSNSYTTDVIGDGGIVYRVGEQGYVSWGAG
                     NANPYAPVQIELQRTYDKALFEKNYRAYIEYTRDSAKKYGIPLTLDQGTSLFTKGIIS
                     HLWVTNYVWGNHTDPYGYLSQMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGA
                     ANPTLTDGTNHAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADG
                     IYRPDVNQAYNTSGNVGYHVSFNMRNFPSKKVYVMMRATNDPEGNTKGGAQDFHDKRW
                     YLNIPKR"
     gene            complement(1965..2189)
                     /locus_tag="RD451_001827"
     CDS             complement(1965..2189)
                     /locus_tag="RD451_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HDT7567085.1"
                     /translation="MNNKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIIT
                     GFGAFLGSVLGVSNRTYKMFSAESEEGGNK"
     gene            complement(2186..2479)
                     /locus_tag="RD451_001828"
     CDS             complement(2186..2479)
                     /locus_tag="RD451_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567086.1"
                     /translation="MINLGEWGAIAGSITAIVSLILLVIKPITASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHAEKLVEHTQQIKTLFRERRK"
     gene            complement(2517..2654)
                     /locus_tag="RD451_001829"
     CDS             complement(2517..2654)
                     /locus_tag="RD451_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HDT7567087.1"
                     /translation="MFSFSDVKMMYDWGCFTNEQVMVFVPLCITEEKADKIISKEESA
                     S"
     gene            complement(2656..3102)
                     /locus_tag="RD451_001830"
     CDS             complement(2656..3102)
                     /locus_tag="RD451_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567088.1"
                     /translation="MKNIWKYGRTGGEYAGKVLDDMLVSVPYTDQPPLEGIRADGEPL
                     TIADQMFDPKLNQWIILANALDHNDLNNLKAMYESLENENGDLKQINAKLMLSDVAIK
                     QENTALKEKADSLAQINSKMMLASLQNSKDISEIKEQLNPASKGGE"
     gene            complement(3099..3248)
                     /locus_tag="RD451_001831"
     CDS             complement(3099..3248)
                     /locus_tag="RD451_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567089.1"
                     /translation="MKAAYRPIEPYGFEQIIVNDEEHLPEECTEVEPPIPNWKPKFNY
                     WEGNK"
     gene            complement(3265..5367)
                     /locus_tag="RD451_001832"
     CDS             complement(3265..5367)
                     /locus_tag="RD451_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567090.1"
                     /translation="MASSLYNLALDFSKELNYTKAIMARQGDKGITVTVKPFLNGLQM
                     DTSGGTFTLKGTTPSNRYVDNVATSVTSEEVTFSLDGTFMSEAGYYKHCYVEYRKDNQ
                     ILTTQDIIFFSLGVSDISQGQADEYVSQLEELIRKYNETFDAFMAEIKGRVDSLNQQI
                     TDLTGQAKTLQDKLDALKEEISKLGNLQVMYSNSIDFGDYDYSGNPNLLSKLSYDLIE
                     NQNTSAGTLSKGENSFKYNKISAEVEGGVELYYKRRGIANWLPSNKTLVMTVKLRAGA
                     DYSPVDGKLILIRYRYVDSGTGKIVLDLPINSNSITQEWKEFSITGTTPTFSPQAYHP
                     WIQFRAQDGILGEIEMSYDIKIEEGSTATPFQPNLLAEPYNMCREYPNENIADHTVKF
                     PIESGDHQIYQGYTEEELMIGQTYTITLKGTKPASQTFVAYNHWTARLGELKPVDGLT
                     DVWSLTFTPTNVVASSPKLFRVYQYPQSTVGACRIDWLKIEKGDTRTPNISEYKYRGT
                     GMRDSNNPKDYVWDLAPEYVEDNLATDIKISEITGKANNYTDGKVSEINSQLTASINE
                     VDTTAKDAQTKANANATAIDELDNKIDERINDTATTTLTVTNGNTGSAKLYREGKTVS
                     IYFVALNGKSSGGNDSTILTIPEGYRPPISFEQLVGSIDRSTLNSAQLSIGADGAIKW
                     RRNSSYGSDYTFAITYTI"
     gene            complement(5391..7682)
                     /locus_tag="RD451_001833"
     CDS             complement(5391..7682)
                     /locus_tag="RD451_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDT7567091.1"
                     /translation="MIDNLITIYDKNDANNLAEHLYDTQGLGALSDWLTATVSNKLNG
                     AEIFQGTYPISGTNADLIVEGRIIQCYVDENRAKQRLRIYYAKTSVIGNTIEVKAEPI
                     FNDIRKSVLNKYDSGTEKITASQAWQNAKTLAKPVIPSQFSFSSLVDTLANVKIEKAN
                     FLEFFGGKEGSILDRFHGEFLKDNNTLRHEKRLGTDHKIKAIYTKNLTGLDLEIDAQS
                     VLVGVYPFISSSSEGEDEITLPEEVIFTDYVDDYPAGYVSFVDFKDKATDVATLREAA
                     KDWLKTNIDKQKPQVSGSIELVPLRHQRGYEKFVDLEKVSMGDGVDVYHPQLKVNMSA
                     RIVEYTFNVLTNSYDKLVVGNVKTNFLENTENNVSNLINDAIDQLKNGGEISDLLNDI
                     VDHQTDMITGQNGGYVLLDPKEAPSRILIMDTPDKNTARNVLQINNAGIGFSKTGING
                     TYETAWTLDGGFNASFITAGEIVGITIRGTTLISDGADYRTSIANGKMTWYSKKVNKD
                     IMELEARDYVSADAGIVSYTMKTGGGFMIRNPQGNLVFSTWDNGNNRPFLSFGAPNFR
                     YSNASYVTSGDGSSLSINGSAGNSWEFKVAGRTMKFTSDGMLTLPGCFFGSWEDGKLA
                     RFEQSTVQVYKDFTVRGTKNSTVPTEHYGQRLLNAYETPEYYFADYGEAVTGDDGKVR
                     VDIDPMFAETVNLSRYMTHVTPTELVLCAVTHEDIDHFIIETSKPNVLVRWNLVAHRL
                     GYEDIRLKEDTAYDSTVLDQKRF"
     gene            complement(7692..8429)
                     /locus_tag="RD451_001834"
     CDS             complement(7692..8429)
                     /locus_tag="RD451_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDT7567092.1"
                     /translation="MTDCIHSIIDGFPDYLHKLALAERPTIPSPKRQRVETSVLGRLG
                     GLVQDYSFEDMSFTLHYNYLEDVEDHQAFKQSFYIMRHWLNYAKKLEFSDDPNVYYVI
                     QTIDIGDAENDIVEWGEFDVNITAKPFARVQEDVPITVDKPQSFNLLNNSLEESFPKI
                     IITPSATSCQFILNDYVFSFEGLVVGTDVVIDSDLMLCYEEQSDGDILDRSNKMKTMQ
                     YPTLQVDINYFNCTGLSKIQIYRNGLR"
     gene            complement(8480..11899)
                     /locus_tag="RD451_001835"
     CDS             complement(8480..11899)
                     /locus_tag="RD451_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HDT7567093.1"
                     /translation="MAKKRTEAEVTFIANDDGLKSTLKEISAELTKNRAELKLEQAQL
                     QQTGSESDKLGSKLSSLEKQYELQSQKVEVTSQRLANAKKYYGENSTEVQKLERELIN
                     QQTAQQRLSNEIDKTSNALAQAKGEIQTYESTMQQLDSEQKNVQASASLIESEYKKWQ
                     ATAGQSASESEKLAKAQEYVSQQSENAEKTIDILRRQLEATQSEFGATSTEAMQMEAK
                     LNDAEREFEELGQAAKNVDTTNLDDIGSKIDMNNLMEASDVLSDIGDKLTELGKQAVD
                     SANSVGSSQSKIQANFGLTKQEAEELTNVARDIYYKGFGESLDQSTDALILVKRNLGD
                     LNNQDLQNITEQAMVLENTMGADMDETLRGVNGLMVNFGLSAQDAMDLMVSGTQNGLD
                     KTHELGDNMAEYSQLWSQMGYSADETFGMLQNGLDAGAYNLDKVNDLVKEMGISLTDG
                     RFEQNMDMFSESTRKAFEEWKNGGGTQKDVINSMIQDFSNMDGQYDQLNKASTIWSAL
                     GEDNAMKVVQSLTDVNHTFDDVSGSAQKMNEDSTTPLQELNGKIAELKDSLAPIGNTI
                     IDALEPVIDFLGKMADAFNNLPQPVQDYAVAIGGLTAAFTLLMPIIVGFMALGGPTTL
                     IIGAVITVIAGVIAIIKNWGAITDWFKGIWSKFTDWLGGTWESIKEGASSVWDGVKET
                     WSGFVDWVQDIWQGVSDWFGELWSGLVEGASNIWQGVQETWQAFVDWVSNIWNGVKEV
                     WSIIWADIVGIVQIPWTLITSLIQAGINIIVGIFDVAGQLLGAAWQAVWTPISDFLKN
                     TWDTMTQWVSIAWNGIVTTFHTIFDPVVAWWNGIWTAISTTASNIWNSISATASSIWN
                     SIKNTITSLVQAAATVIQNIWSTVSSWLGGIWNSISSTASNIWNSVTSSISNAINAAK
                     SAIQSVWNSISSWISGIWNGIKNTALNLWNGITSTISSKVNDGKNAISSGWSNLTGIV
                     SDIFNNVKSTIANIWEGIKKTVSAPIDWIRDKISSIFDNLNISIPHIPLPHFKLSGEF
                     NPLKGKIPTLGVDWYAKGSVFNSPNIIGVGEAGPEAVLPLKRSVLQEIGDRILSSTSV
                     SSRAQTIQPVNNYEFNFTIDGNADEVTMKQTTQQIIDSITKVQNDNASAWR"
     gene            complement(11916..12098)
                     /locus_tag="RD451_001836"
     CDS             complement(11916..12098)
                     /locus_tag="RD451_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567094.1"
                     /translation="MPKLLVETWVDVYSMLTDVFSMPSDLVLSDICLDDILQMAYNKS
                     AYEGWKNYAINQSQKN"
     gene            complement(12101..12463)
                     /locus_tag="RD451_001837"
     CDS             complement(12101..12463)
                     /locus_tag="RD451_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567095.1"
                     /translation="MNEDYSKIELNDGTILNLEPKLNIKKLLMINRDFNTDEFAKMTV
                     GKGSMDISVIQGAKAVYIAYRQANMTDYISFDEFIDKWDFDMATASYIYQLMMFKQAR
                     DAYQKEFEKANKEKKLQK"
     gene            complement(12483..13088)
                     /locus_tag="RD451_001838"
     CDS             complement(12483..13088)
                     /locus_tag="RD451_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDT7567096.1"
                     /translation="MAKTTTVTTFDNISIKRISFNFKNATNAISTDCNGQLDGETEMQ
                     RIVKKCGSTEVKSKSKPINMTVTITAHVPMEVYRRFNGLKQDERIKSGIYSYGPDSVG
                     EDFSLAAEIVDDFEEKNKLIGMLACTSNTGLTFSIENGADEVAALELETKVMQDEFGK
                     FYHEAIVAELEEDLTDQWMTNLSADVIKKTSVVTTTATQSQ"
     gene            complement(13100..13504)
                     /locus_tag="RD451_001839"
     CDS             complement(13100..13504)
                     /locus_tag="RD451_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567097.1"
                     /translation="MAKNSWELKINGHDELLVRMERYSSESERLINEALKSKGSAIAV
                     DRITEKIPVSEADLRRGHQHAKNSRPLKTQYINLGFIIRPTRKFEYLKYPDLGIGTSK
                     RNQPDEFMRRGLGLALDPITELLIRQFDKLNK"
     gene            complement(13497..13898)
                     /locus_tag="RD451_001840"
     CDS             complement(13497..13898)
                     /locus_tag="RD451_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567098.1"
                     /translation="MVIDNSKEKERLNKQISAIKTSLEEHFGLKLFQDSVGEDELPDD
                     FNYFILETGEIEMITEPKYSVGQNLYLTFYSENREDLTGDSLDIISLIQNRSIRFQRM
                     DPNHLKLENQDRYIDQLVFTFRRLLKSDCHG"
     gene            complement(13888..14241)
                     /locus_tag="RD451_001841"
     CDS             complement(13888..14241)
                     /locus_tag="RD451_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HDT7567099.1"
                     /translation="MANNRRLEETFNDGWLKILTQTTKRNELGKKIGVEDTEITSLKF
                     RNLSMRDSDITAMDAMGSKLTKKVKTPFHPIAKKFNKDQYFIVIDSMRYNVIYADYDN
                     FYIYFYLESVGEYGD"
     gene            complement(14231..14542)
                     /locus_tag="RD451_001842"
     CDS             complement(14231..14542)
                     /locus_tag="RD451_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567100.1"
                     /translation="MTPEQVTEELLIAVKDNIYVTWNEEDESIKKMIAKNAVYLQSKV
                     STTLSFSPESLEYGLLIERCRYDWNRALDEFEQNFASELLGFIQHYALQEYIAGDVNG
                     E"
     gene            complement(14539..15414)
                     /locus_tag="RD451_001843"
     CDS             complement(14539..15414)
                     /locus_tag="RD451_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567101.1"
                     /translation="MKYILCQPAINRFKWELEVCLTNLKKLGIKDIVLLFSRHDDQIP
                     IFFEKEYGVEVHVYDDLRDDKEYIPSIKPYLWWKYLEEDHSREDDRYFYIDSDVIFNK
                     RINLRKLPSKDDVWYCSDCCSYLSLDYIRSCENGENILKDMANIVNVTVESLETINTN
                     SGGAQWVINRPKANYWKKVYLDSNRLYRYLRGQKTNIKIWTAEMWAQLWNMMYFNIGP
                     KVHEELDFCFATDPIEKVKEVKILHNAGVTTNDEDLFFKGRYVTSTPFDEDLSFVNKK
                     KCSYAYVKAIKAVVR"
     gene            complement(15424..16584)
                     /locus_tag="RD451_001844"
     CDS             complement(15424..16584)
                     /locus_tag="RD451_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HDT7567102.1"
                     /translation="MTVKNLKGVTAASDQLMKAFKDGNEESFSAAMVSLSKEIQDKIL
                     EEATAKNQDQLVLMNRGQRVLTTQETKFYNEVVKNEGFAGVEELVPATVFERVFEDLE
                     QSHPLLQKITFVNTTGVTEWIVSRGVNPAWWGKLCEAVKKVLDNGFDVINMKQFKLSG
                     YIPVCKAMLDLGPVWLDRYVRTVLVESLRIALEQAIVDGTGKDMPVGMMRDMSKQTSG
                     EYAEKKAEPITALDAVTMGGLMARLSKFNIEGVNDPIYRNVNPSDVVLIVNPTDYWSK
                     VFPAKTVLTANGEYVQVLPVPVSDLQSTAVPEGKAVIGVASDYFMGVGSTLKIEASDE
                     YHFVEDERIYLAKQYANGQPKRNDSFIVLDISALGTTTTTTKPTTTTTTTQA"
     gene            complement(16584..17270)
                     /locus_tag="RD451_001845"
     CDS             complement(16584..17270)
                     /locus_tag="RD451_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HDT7567103.1"
                     /translation="MTTMKTFLAVKNEGAVPQIFIQGFIGSSWFFEGNTDKGIKNILD
                     SLGDQEEIEVVINSNGGDVFQGIAIGNLLKSNKAKVNVVINGLAASAASIIAMAGDTI
                     KIYNNAQLMIHRASTYGEGNVDDFRTIADQLESIDKSVKASYKTRFNGTDEALQELLE
                     KESFMDAETALSYGLVDEIIDAENSSGTEAKKEQSVEEILNDVKEKRAEKIAAFTAAL
                     NKTFGQGDVK"
     gene            complement(17233..18411)
                     /locus_tag="RD451_001846"
     CDS             complement(17233..18411)
                     /locus_tag="RD451_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDT7567104.1"
                     /translation="MGIFQKAVGYFTKKATVPLEEYFCKLQVDFVYRKFAIETCIDLI
                     ANAMSKAEFKSYEDGKNKKNDLYYRLNVAPNKKNNATEFRKKLIRRLIFYNEVLIVSP
                     SNNSSEIFIADSWDVTEYALKDDVFSQVQINNIVLDREFLESDVIYIKYADQQIRQLV
                     DAYYQAYGKLISSAMNVYKRSNARRYVLKGNLFRPQDNTTQDQINKMMTSQFKAFMEA
                     DNAGAVFQLQNEYTLEDFSGNFQSNSRDIKNLIDDIFEMTAAAFHVPKNLLKGDMSGL
                     SDQVDAFLMFEIIPIAELIQDAFNASLYEVEEYLSGNFVRVDTTMIKITSFKDLVDAI
                     DVGIRNGVFTINEGRERVGNDRSDKAMADEIFITKNNQQVSKGGEANDDNENISSSKE
                     "
     gene            complement(18431..20125)
                     /locus_tag="RD451_001847"
     CDS             complement(18431..20125)
                     /locus_tag="RD451_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HDT7567105.1"
                     /translation="MNQFLSYKHIENWFKAIEEGTIKVCKEQLLLKNYLEERVFTRED
                     IYFDKQMVEDSINIPAQYFPFELIPWEKFLQCFIYGVRWKKDKTLVFNRYLSLMGRGN
                     GKTGFASWNNFFLLTAKHGIKNYDIDIYANNESQAKTSFDDVFKVIKDHPDLDKKVFK
                     ATKEVIQNIATNSKLRYNTANARTKDGKRPGANRFDEIHENEDYSMINVATSGGGKIR
                     DYREFYDTTNGHVRGGPLDDIIEESKMILSGELGIDKDGAEFSSLFPFICRLDNDNEV
                     DDPDMWEKACPTINYNADLKRKMFQEYSQMQRNAGLRLTFMTKRMNRPMEDTRFAVAS
                     YDDVLHTKEKEFPEKMDEVIGTVDFADRRDFASVGLLGKYDKDVYFTQHTFIHESALR
                     LQNIKREVIDISIDQGKSQIVHGKNIEADYIVGWFLEMSNKYYIKKIAMDMYRAKILK
                     PALEEAGFTVEIVRSGSVTHGMLKDLVDDLFINQRLFFGDDAIMRWYCMNVYEEHISN
                     GNIRYEKIEPETRKTDGFFSFLHGLNFLDDIYDSAPVTVTNSSVENTGTGFTPLVF"
     gene            complement(20103..20417)
                     /locus_tag="RD451_001848"
     CDS             complement(20103..20417)
                     /locus_tag="RD451_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HDT7567106.1"
                     /translation="MFKNELSQNRYREKLRRSLISQLESQKTNIEPFLDNVDRYISLW
                     ETAISLEEDISENGIRLENGKKNESVALLVSVNKQMGLMLDKLAITPELVGEANESIP
                     EL"
     gene            complement(20520..20801)
                     /locus_tag="RD451_001849"
     CDS             complement(20520..20801)
                     /locus_tag="RD451_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567107.1"
                     /translation="MIINDNGREYDTEKIEEYSSYTQGLIKRLIYVRYVGIRDLLSDN
                     CCSKYKVNQVREALNKDNNVERIKNVFGYSIEEINYYIDFAEAFIPMVR"
     gene            complement(20806..21150)
                     /locus_tag="RD451_001850"
     CDS             complement(20806..21150)
                     /locus_tag="RD451_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HDT7567108.1"
                     /translation="MTEEFYRWLLQLIREDRLVKFYQSPKWRRLREKAMKRDHYECQE
                     CRRLGKYHRVENVHHIKEVKDRPDLALDLDNLICLCVEHHNEVHGRYLTALDKQEKKI
                     ESFANFDASERW"
     gene            complement(21410..22057)
                     /locus_tag="RD451_001851"
     CDS             complement(21410..22057)
                     /locus_tag="RD451_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567109.1"
                     /translation="MVGVVKFLGFTFDGYGTLGEWVGIILIVITIQQTSKYYWYSNSS
                     KIVSRITEGITKKDITVVGKYGFTITLLNEGKSETAIKFCGIIGKYNIFQRFIRKHWY
                     KYIYKYPVVKKLIEKYVDHEISYLNPTDLINQEFQNIGYLEKGLKIPIVNESLVTAMV
                     ANIKNSKKLEKRYKKCKKLKFSFLFLEYNGKEYYQDIYVLRGSNLYKDIKNKISV"
     gene            22267..22458
                     /locus_tag="RD451_001852"
     CDS             22267..22458
                     /locus_tag="RD451_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegP family protein"
                     /protein_id="HDT7567110.1"
                     /translation="MVKNLYFVIREATNGQYYFVIKSNNNEVVATSETYLTKYSAEQT
                     INSIKNGITKDSQVIDMTK"
     gene            complement(22451..22792)
                     /locus_tag="RD451_001853"
     CDS             complement(22451..22792)
                     /locus_tag="RD451_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567111.1"
                     /translation="MEVEQIKYQGMDRERLIDIIEQQRLELIQKEAVCKEYKKHLEQV
                     IEYHSVEKYRSVVQKNRATSPDSRQDVSISIKTPVFNSVKSEKLESISTALVEKAAEM
                     NSLANEVSRLI"
     gene            complement(22816..23052)
                     /locus_tag="RD451_001854"
     CDS             complement(22816..23052)
                     /locus_tag="RD451_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567112.1"
                     /translation="MYWRVYKMKIASEKIDQLTILVNQRIEDIIKEFEGEKIKNIKLT
                     LMDHKFELNSTKRKIVELIEEEIALQINEQQLAN"
     gene            complement(23327..23794)
                     /locus_tag="RD451_001855"
     CDS             complement(23327..23794)
                     /locus_tag="RD451_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HDT7567113.1"
                     /translation="MVLFDVKKYETPSAKDVDMERTKHNVAVFLSAYLSARCRVGQPR
                     EPKVTASYSLVPPSTADHIFEAERMLIDKEEAQEEFEYLHKLFVRGYSAIQHPHKPDV
                     TERRKKIFYDRYINGLPIYVTAQRNNTSEESVKVESNRIIIQFASSLELVAFK"
     gene            complement(23869..23958)
                     /locus_tag="RD451_001856"
                     /pseudo
     CDS             complement(23869..23958)
                     /locus_tag="RD451_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293000.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
     gene            complement(23979..24197)
                     /locus_tag="RD451_001857"
     CDS             complement(23979..24197)
                     /locus_tag="RD451_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567114.1"
                     /translation="MDLYDIESGATLSVESDHLIINFGGKRQIILWVVDDVLFPEIVH
                     DFEESKAVEFEIVKKVMELIEKYEEDSE"
     gene            complement(24184..24540)
                     /locus_tag="RD451_001858"
     CDS             complement(24184..24540)
                     /locus_tag="RD451_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HDT7567115.1"
                     /translation="MDLITQYSDIILKKIMMKIQKDKKSKERAELVKLEMAETGAGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLHQDRFKFVEKYKEILEEYLR
                     RTANDKKTRSIQHGFI"
     gene            complement(24540..24845)
                     /locus_tag="RD451_001859"
     CDS             complement(24540..24845)
                     /locus_tag="RD451_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567116.1"
                     /translation="MSVDKKATMKRIAELTKSESWQEDKEIVAEVQKLGKSMWTEKPK
                     RKTPRKIAIWHGDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEER"
     gene            complement(24842..25003)
                     /locus_tag="RD451_001860"
     CDS             complement(24842..25003)
                     /locus_tag="RD451_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HDT7567117.1"
                     /translation="MTTEEVIQMRIRNIQREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIRRLEE"
     gene            complement(25018..25377)
                     /locus_tag="RD451_001861"
     CDS             complement(25018..25377)
                     /locus_tag="RD451_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HDT7567118.1"
                     /translation="MNKYRNKKTVHRGIKFDSIAEAEYYDLALWQAEANGWKVKLQER
                     FELMPKFELDGKKYRKIEYIPDFTFYKNGKLVKVVDVKGMQTKDFKIKAKLFCHQYQA
                     PLILAKKYRNTFKEERF"
     gene            complement(25374..26225)
                     /locus_tag="RD451_001862"
     CDS             complement(25374..26225)
                     /locus_tag="RD451_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDT7567119.1"
                     /translation="MESLANAMEKLIRRVLVQSGKCPECSEPLYSWRAKNKDGSERCK
                     PTCMSCGYKALRVKEDIQTERIYNDSLKARALSFFQNGSVLTDKTLFKCKMENYHVVD
                     QETKIALEKAKSYTNEVLLNHPAHFILSGKSGSGKSHLSMATAWEILERSNYDKKILF
                     ISYQELLEQIKFSYNNTELRKEIEGSLIADIKTTDLVVFDDIGAELGSGVSNSRQFTN
                     NTLNTLLEARQNKATIITTNLSGPELREAYGERIVSRIFKNSEGYALKFQQTADKRIK
                     PVKGSIA"
     gene            complement(26242..27072)
                     /locus_tag="RD451_001863"
     CDS             complement(26242..27072)
                     /locus_tag="RD451_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HDT7567120.1"
                     /translation="MAEISWIKLKTTMFDDEKIRLIQAVPESDAIIVIWIRLLVLAGK
                     TNDDGLIYIQRNMPYTEEMLATLFGKNVNTVRLALTTLANFNMIDLSSDGLIAISNWE
                     KHQNIEGMDKVRLKNAERNRKYRERKRQERLKLENDVSVTSRDGTDKDIEEDKDIDKE
                     EKKGKYSDEHLRLAKKLQSNLTEDFPKEMNKVDIEKWADTIRLMEERDKASIEAIEYV
                     INWLPTNEFWFGNIRSAKKLREKFEKLKFEIKADKKNHKKQSQKLQYSNPSEYDDLPI
                     "
     gene            complement(27075..27761)
                     /locus_tag="RD451_001864"
     CDS             complement(27075..27761)
                     /locus_tag="RD451_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567121.1"
                     /translation="MFKPLIDSYSAVLKKFKGNDIGATINEEVNIERLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGREISLK
                     DESNTTVSDANILANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHSEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     ETIKKLRIGG"
     gene            complement(27767..28006)
                     /locus_tag="RD451_001865"
     CDS             complement(27767..28006)
                     /locus_tag="RD451_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567122.1"
                     /translation="MENELSTLDQYLADPDWGKSNLQLVANKYEKSIDEAIVALTDAA
                     SITADDSKWTKRDLGILKRGVNWLEDQYREETKEK"
     gene            complement(28332..28520)
                     /locus_tag="RD451_001866"
     CDS             complement(28332..28520)
                     /locus_tag="RD451_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567123.1"
                     /translation="MSYTLQQEHQILGLIKQRRKQLQDDRAALRKSDELSDRQAELIA
                     SELEDLRMLEIKNREIRL"
     gene            complement(28541..28825)
                     /locus_tag="RD451_001867"
     CDS             complement(28541..28825)
                     /locus_tag="RD451_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567124.1"
                     /translation="MQITIPDNLVVSELTTQITNAVLNSLDERLHLMNKSVELPPYPN
                     KSEVKKVLGIGDDKLTHWISLGLKTQQWSKLDIRIERSELQRFLKENFEF"
     gene            complement(28827..29015)
                     /locus_tag="RD451_001868"
     CDS             complement(28827..29015)
                     /locus_tag="RD451_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7567125.1"
                     /translation="MSQEFILKVRIQLAKYGKSQNWLADTIGISRPYMSDIMNGRRKP
                     DKQIKPIEAALAELEKEK"
     gene            complement(29018..29794)
                     /locus_tag="RD451_001869"
     CDS             complement(29018..29794)
                     /locus_tag="RD451_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HDT7567126.1"
                     /translation="MNTPQIFNFEQHEVRTVTIHDEPFFVGKDVAKVLGYQNGSRDIN
                     RHVDVEDRQNYQNGTFESPRGLTIINESGLYSLILGSKQPNAKKFKRWVTSEVLPAIR
                     KHGGYLTPEKVEEALLNPDTIIQLATKLKEERTGRLIAEQKIAEYEPKISYLDSILSS
                     TDSVTISQIAADYGMSPQQMNKLLHKLGIQKKVGNQWLLCKKHMRQGYTKSHTTEIPK
                     SDGGTKVVMNTKWTQKGRLFIYESLKKEGYIPEIDLLEEE"
     gene            complement(29921..30142)
                     /locus_tag="RD451_001870"
     CDS             complement(29921..30142)
                     /locus_tag="RD451_001870"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567127.1"
                     /translation="MKQNKKTPSAKGALITLNFKDQKFSAVVDEIHPQEHQKNSFATD
                     EKKTQKRSEKVLRIIQFLLEKIRHFGSLF"
     gene            30443..30787
                     /locus_tag="RD451_001871"
     CDS             30443..30787
                     /locus_tag="RD451_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7567128.1"
                     /translation="MLFERVKELCKKRGISISELENRIGFGKNSIYKWKTQSPKIETL
                     QKVADYFHVSTDYLLGRTDDPNAGVAPEERKLTVEEALASVMSSDGKPLTDNDREILS
                     AMIEAYLEKKDN"
     gene            30823..31218
                     /locus_tag="RD451_001872"
     CDS             30823..31218
                     /locus_tag="RD451_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HDT7567129.1"
                     /translation="MIINELGVKVEERENLDADGHYVACMNTIVIKANLSKYRRQRTL
                     LHELGHASKHHDNYFLYNLAFSLHSKMEYEADRFMIEKLLDRYIAKSELEPHNINYMK
                     FIEDNNLSVRFEPLVKELLKARIYCYAAL"
     gene            31271..31582
                     /locus_tag="RD451_001873"
     CDS             31271..31582
                     /locus_tag="RD451_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567130.1"
                     /translation="MIYTEFKEWLEKSTTGYETFIIKATNYQIEKNKNRPQKKRWDDK
                     KIDKAVLEMWKQVVTNLYQTIRKEKGVPLINGKEIWLEFIEEQGLIEFFNDSMAELEF
                     E"
     gene            31594..32742
                     /locus_tag="RD451_001874"
     CDS             31594..32742
                     /locus_tag="RD451_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDT7567131.1"
                     /translation="MAMIKQYKKKNGEKAWYFKTYLGIDPLTGKKKYTTKRGFRTQKE
                     AKTALSRLELELQKTGMPTSTNTTFKEAAELWLESYKKTVKESSYSRTKIIFNKHIYP
                     KFGNIKLSKINTAYCQKVVNDWSEKGTSKQYPLFINYMNKVFKYAINIGLTSDNPTLN
                     LLIPKPQIKTEKKLKLYTKEQLELFLNEVSQEQNPYFKNRDYTLFRLLAFSGCRIGEI
                     LALTWDNINFKTNEMAIKKTVARSDKYYISETPKTKKSNRIIYLDEKTIKQLKFWKLE
                     QRKYLFQLGFTKANYLFTNDENNFTINQSVAERYNIYRERAGLPYIGLHGFRHTHASM
                     LYEAGADHKEVQERMGHANIKTTMDTYTHITNSKKEETTQKLTNYINF"
BASE COUNT         9582 a         6635 c         4987 g        11628 t
ORIGIN      
        1 catgaaaaat cctccagtgt gttttttatt attctacaca ccttattttt tctgtctagt
       61 ctagtgtagc cgattcatga ctgacgtgcc ggacgcacgt agcgatcatc ggcgttatga
      121 ctatataaag tatactttcg ttgatccaga aaggtataaa gattaaagta ggctacctaa
      181 aaaggtagcc cggaacgaat tttatcacca tacttgtgaa aggagatatt ttttaagtta
      241 gtattaagat tgtgtaatat gatgatatct atattttata gtatcagtgc tataaaatca
      301 aaaataagtc actaattaac taccactcca attgtaagcc ttttttctca ctttttttca
      361 aaaatatggt atgcttttta atggcttcaa atataaaaga gtttaaagcg taacacactt
      421 atggggaagt ggtttggggt gcgctttaaa ctcttcttta ttattatctc acaatttaac
      481 ccaaatgtct ttctatttaa aaatcaaagt aaaacttttc aaatatacag aagtataact
      541 atgtgaaaca tcctttcatt aatccataaa aggatacata aaaaagccac tcatttgagt
      601 ggcaatgaag aaaagcttta gcttgtataa tactcttcaa aaaaattcta acacagaacg
      661 attcaaatgg ctacgttaat gtaccctgta ggactcgaac ctacgaccgg acggttatga
      721 gccgtctgct ctgaccaact gagctaaggg tactggttgt tgccacataa agccataaac
      781 aatcaaccag tagaatgtgt ggcaacaaac ctgttatcgc atagcttgga gtgtgactat
      841 ttatgggtga tagtgaagat atgcgataac atcactattt tatcgaataa tttttatagt
      901 tgtcaatata gttatgtact gctcctcaac gaggagctat ttttatcgtt taggaatatt
      961 taaataccaa cgtttgtcat ggaaatcttg cgcaccgcct ttagtgtttc cctctggatc
     1021 attcgttgcc cgcatcatta catagacttt cttactagga aaattacgca tattgaaaga
     1081 tacatgataa ccaacatttc cagaagtatt ataagcttgg tttacatctg gtctataaat
     1141 tccatcagct cttactcgag ctaattcttt cccagtattg tagtccataa tgaaaatata
     1201 ctcgtattta tagttagcaa tgtgccatcc agccacatgc aagtttgcgt tttcgatttc
     1261 cccaaactga tcaatgtggg cgtgatttgt tccatctgtc agcgtaggat tagctgcacc
     1321 agctcgtgtt ggatcaatga caggcttgtt ttcagaagtt gttggatttt catcggtaaa
     1381 tccatgagct aaatcataag caagcttttc tttgctaact cccatttgcg ataagtaacc
     1441 atatggatct gtgtggttcc cccaaacata atttgtcacc cacaaatgag aaatgattcc
     1501 ttttgtaaat aaagaagttc cttgatcaag agtcaatgga attccatatt tttttgcact
     1561 atctcttgta tattcaatat aagctcgata gtttttttca aacaatgctt tatcatatgt
     1621 gcgctgtaat tcaatctgta caggcgcata aggattagcg ttaccagctc cccacgaaac
     1681 atatccttgc tcacccacac ggtaaacaat cccaccgtca ccaataacat ctgtagtata
     1741 agaattgctt ccgttataat tatttttcat gttggcggct acgtttcttg ctggtgcatc
     1801 tattccagtt tcgtgcaaaa taattttgtt aggaattgct aatctggagt ctccttgatt
     1861 cggcgctaaa ttatactcgt cattaatagt ataagcaaac gtattaatgg gtaataaaaa
     1921 aagagccgtt aacaggctca tcgcagtaat agtaattttc tttttcattt gtttcctcct
     1981 tcttcgcttt cagccgagaa cattttgtag gttcgatttg atacacccaa cacactccct
     2041 aaaaacgcgc caaaaccagt aatgatgaca acacagatat ctgtgtactg ccaattgagc
     2101 gctttaccaa ctaaccccac gaaagtagct agtgcgggaa taattaccag tgcgaaccat
     2161 tttagtactt cgaacgtttt attattcatt ttcttctctc cctaaataaa gttttaattt
     2221 gttgcgtgtg ttctaccaat ttttctgcat gtgtatctaa tctttcatcg tgtttcttta
     2281 gttcttcatg aatcatcaat cgatctgatt tgctcgattc taaatcttta gtcagcaaat
     2341 ctaaattgtg acttactttt gaaagagtct cagtaatctt cgagaaagat gcagtaattg
     2401 gttttattac taataaaatc aaagaaacga tagcggttat tgatcctgct atcgctcccc
     2461 attcccctaa attaatcatg tgacaactcc ttgaatcaaa ataaaaagca catcaattaa
     2521 gatgcgctct cttctttgct aatgatttta tctgcttttt cttcagtaat gcacaacgga
     2581 acgaaaacca ttacttgttc gttagtgaaa cagccccaat catacatcat tttcacatcg
     2641 ctaaaactaa acatactact cacctccctt tgaagctgga tttagttgct ctttaatttc
     2701 tgaaatgtct ttgctatttt gtaacgaagc aagcatcatt tttgaattga tttgtgctaa
     2761 actatccgct ttttctttca atgcagtatt ttcctgttta attgctacat cgcttagcat
     2821 gagtttggca ttgatctgtt ttaaatcgcc gttctcattt tctaacgact catacattgc
     2881 tttgagattg tttaaatcgt tgtgatctag tgcgttcgct aaaataatcc attgattcaa
     2941 tttaggatca aacatttgat cagcgattgt taacggttcg ccatcagcac gaattccttc
     3001 aagcggtggc tgatctgtgt aaggaacgga tacaagcatg tcgtccaata cttttcctgc
     3061 gtactctccg ccagtacgtc catatttcca aatgtttttc atttatttcc ctcccagtaa
     3121 ttgaatttcg gtttccaatt tggaatcggt ggttcgactt ctgtgcattc ttccggtaaa
     3181 tgttcttcat cattcacaat gatttgctcg aatccgtaag gttcaattgg tctatatgct
     3241 gccttcatat cgattcacgc ttttctaaat cgtgtaagta attgcaaagg tataatccga
     3301 tccataactt gagtttcttc gccatttaat ggctccatct gcaccaatag ataactgagc
     3361 actgttcaaa gtagaacggt ctatcgagcc aaccagttgc tcaaaactaa ttggtggccg
     3421 atagccttct ggaattgtta gtatcgttga atcatttcca ccactgcttt ttccgtttaa
     3481 agccacaaaa tatatagaaa ctgtttttcc ttcacgataa agctttgctg atccggtatt
     3541 cccgtttgta actgttaatg tggtagtagc tgtatcatta atgcgttcat cgatcttatt
     3601 gtctaattca tctatagcag tcgcattagc attcgctttt gtttgagcat ccttagctgt
     3661 ggtgtctact tcattaattg aagcagtcaa ctgcgaatta atctccgata ctttcccatc
     3721 ggtataattg tttgctttac cagtaatttc agaaatttta atatctgtgg ccaagttatc
     3781 ttcgacatat tctggtgcta gatcccaaac ataatctttt ggattgtttg aatcacgcat
     3841 accagtacca cgatatttat actcactaat attcggggtt cgtgtgtcgc ctttttcaat
     3901 cttgagccag tcgatccggc atgcgcctac tgttgattgt ggatactgat aaacacgaaa
     3961 aagtttaggt gaactcgcca caacattcgt tggtgtgaat gttagagacc atacgtctgt
     4021 caacccatca actggcttta gttctcctaa acgagcagtc caatgattat acgctacaaa
     4081 ggtttgactt gcgggttttg ttcctttaag cgtgatagta tacgtttgac ctatcataag
     4141 ctcttcttct gtgtaacctt gatatatttg gtggtcgcca gattcgattg ggaacttaac
     4201 tgtatgatcg gcaatatttt cgttaggata ttcgcgacac atgttgtaag gttctgctaa
     4261 taagttaggt tggaatggtg tagctgttga gccttcttcg attttgatgt catagctcat
     4321 ttctatttcc ccaagtatcc catcttgagc cctaaattgt atccaaggat ggtatgcttg
     4381 tgggctaaat gttggagtag ttccagtaat actaaactct ttccattcct gagttatcga
     4441 attactgtta ataggtaagt ctaaaacaat cttgccagtt ccactgtcaa catacctata
     4501 tctaatcagt ataagttttc cgtcaactgg actatagtcc gctccagctc taagcttaac
     4561 agtcattaca agcgttttat tagatggtag ccagttagct atacctcttc gtttataata
     4621 tagctctact ccaccttcca cttcagctga tatcttatta tatttaaacg agttttcacc
     4681 tttagaaagt gttccagctg aagtattttg attttcaatt aagtcgtatg atagcttact
     4741 taacaaatta ggatttccac tataatcata gtccccgaag tcgatgctgt tactgtacat
     4801 cacttgtaag ttacctaact tagaaatttc ttctttcaga gcatctaact tgtcttgtag
     4861 cgttttagct tgaccagtta aatcagtaat ctgttgattt aagctatcca ctctaccttt
     4921 gatttcagcc ataaaagcat caaaagtttc gttgtacttt cgaatcaact cttctaattg
     4981 cgaaacatat tcatcggctt ggccttgcga aatgtcagac actcctagtg agaaaaaaat
     5041 gatatcttgc gttgttaaaa tttgattgtc ttttctatat tctacgtagc agtgtttata
     5101 atatcctgct tcactcataa atgtgccatc aagagaaaac gtgacttctt cactagttac
     5161 actagttgca acattatcta cgtaacggtt agatggtgtt gttcctttta aagtaaatgt
     5221 tccgccactc gtatccatct gcaagccatt tagaaacggt ttaaccgtca ccgtaatccc
     5281 tttatcacct tgacgagcca taatagcttt ggtgtagttt aattctttgc tgaaatctaa
     5341 agccaaatta tataaactgc tagccattta tatacctcct tgtcttcgtt ttaaaaacgt
     5401 ttttggtcaa gcactgtgct atcatatgct gtatcctctt ttaatctaat atcttcatac
     5461 cctagacggt gtgccactaa attccatcta actaatacgt ttggcttact agtttcaatg
     5521 atgaaatggt caatatcttc atgagtaaca gcacacaaaa ctagttctgt aggtgtcaca
     5581 tgtgtcatat accgacttag atttactgtt tcagcaaaca tggggtcaat atcaacacga
     5641 actttaccat cgtcacctgt aacggcttcc ccataatcag cgaaataata ttctggagtt
     5701 tcataagcgt tcaatagtcg ttgtccataa tgttctgttg gtacagttga gtttttagta
     5761 cctctaacag taaaatcttt atatacttgt accgttgatt gttcaaacct agcaagtttc
     5821 ccatcttccc atgaaccaaa aaaacaacct ggtaacgtta gcataccatc actagtaaat
     5881 ttcatagtcc taccagctac cttaaattcc catgagttac ccgcactacc attaatgctt
     5941 aaagaactac cgtcgccaga agttacataa ctagcattgc tatacctgaa attgggcgca
     6001 ccaaaagata gaaacggtct gttattacca ttatcccacg tactaaaaac caagttaccc
     6061 tgtggatttc taatcatgaa accaccacca gttttcatgg tgtatgatac aataccggca
     6121 tcagcactta cataatcacg tgcttctagc tccataatat ctttgttaac tttttttgag
     6181 taccaagtca ttttgccatt agcaatactt gttctataat cagcaccatc actaattaat
     6241 gtagtacctc taatagtaat tcctactatt tcaccagccg taataaacga ggcattgaat
     6301 ccgccatcta acgtccatgc cgtttcatat gttccattaa tgccagtttt agaaaaacca
     6361 ataccagcat tgttgatttg taaaacattc cttgcggtat tcttatctgg tgtgtccata
     6421 atcaaaatac gactaggcgc ttctttagga tctaataaaa cataaccacc attttgacca
     6481 gtaatcatat cagtttgatg atctacaata tcattgagta aatcactgat ttcgccaccg
     6541 tttttcaatt gatcaatggc atcattaatc aaattgctga cattattctc tgtgttttct
     6601 aagaagtttg ttttgacgtt tcctacaact aatttatcgt atgaattggt tagaacatta
     6661 aacgtatatt ccacaattct cgctgacata ttcactttta actgtggatg atacacatct
     6721 actccgtcac ccatcgaaac tttttctaga tcaacaaatt tttcatagcc tctttgatgc
     6781 ctcaatggta ctaattcaat cgaaccactc acttgtggtt tttgtttatc tatgtttgtt
     6841 ttcaaccagt ctttagcagc ttcccttaat gtggctacat cagtcgcttt gtctttaaaa
     6901 tcaacaaaag aaacatatcc agcaggataa tcatccacgt aatccgtgaa aataacttct
     6961 tctggtagag tgatctcgtc ttctccttct gaagagctgc taatgaatgg ataaactcca
     7021 actaaaacac tttgagcatc aatctctaag tcaagaccag ttaagttttt agtataaatc
     7081 gctttgattt tatgatccgt gcctagcctt ttttcatgac gtaatgtgtt attatctttt
     7141 agaaattccc catgaaatcg atctagaata gatccctctt ttccaccaaa gaattctaaa
     7201 aaattcgcct tttctatctt cacattagca agcgtatcta ctaatgacga gaaagaaaac
     7261 tgtgaaggaa taactggttt cgctaaagtt tttgcgtttt gccatgcctg actagcagtg
     7321 atcttttctg ttccactgtc atatttattc aacaccgatt ttcttatatc attgaaaata
     7381 ggttcagctt ttacttctat cgtattgcct attacagaag tctttgcata ataaatccgt
     7441 agacgctgtt ttgctcgatt ttcatctaca taacactgaa taatacgtcc ttctacaatc
     7501 aaatctgcat tagttccgct tattggataa gtaccctgaa atatctcggc tccgtttaat
     7561 ttattgctaa cagtagctgt taaccagtct gacaaagcgc ctaaaccttg cgtatcatat
     7621 aaatgttcag ctaaattatt cgcgtcgttt ttatcgtaaa tagttattaa attatcgatc
     7681 atctatttca cctaccttaa cccattacga taaatttgta ttttgctcaa accagtacaa
     7741 ttaaaataat taatatccac ttgcaatgtc ggatattgca tggtcttcat tttgttggac
     7801 cgatctaaaa tatctccgtc cgattgctct tcgtagcaaa gcatcaaatc actatcaatg
     7861 actacgtcag ttcctactac taagccttca aaactaaaca cataatcatt taagatgaac
     7921 tggcatgaag tagctgaagg agtgatgata atctttggaa aactttcttc taaactatta
     7981 ttcagcaagt taaatgactg tggtttatct acggttatag gtacatcttc ttgaactctt
     8041 gcgaatggtt tcgcagtaat atttacatcg aactctcccc attcaacaat atcgttttct
     8101 gcatccccaa tatcgatagt ctggataaca taatagacgt tgggatcatc agagaattct
     8161 aatttctttg cataatttaa ccaatgacgc atgatataaa acgattgctt gaacgcttga
     8221 tggtcttcca catcctctaa atagttatag tgcaatgtaa acgacatgtc ttcaaacgag
     8281 taatcttgta ctaagccacc taaccttcct aaaacagaag tttcaactct ctgtcttttt
     8341 ggagaaggta tggttggtct ttcagctaaa gccaatttat gcaaataatc aggaaatcca
     8401 tcgattatag aatgtataca atcagtcatt ttttcacatc ctttttaata ctaaaaaaac
     8461 aggagaaata ctctcctgtt taacgccatg ccgaagcatt atcattttga acttttgtaa
     8521 tgctatcaat gatttgttga gttgtttgct tcatagtaac ctcatctgcg ttaccatcaa
     8581 ttgtgaaatt gaattcgtag ttattcacag gttgaatcgt ttgtgcccta gatgaaactg
     8641 atgtgctact caagatacga tcaccaattt cttgcagcac agatcttttc aaaggtaaaa
     8701 ctgcttcagg tcctgcttcg ccgacaccga taatattcgg agaattaaac acactacctt
     8761 tcgcatacca atcaacaccc aacgttggga ttttcccctt caatggattg aattctccgc
     8821 tcaatttaaa atgtggtaac ggaatatgtg gtatagaaat attcaaatta tcaaagatac
     8881 tactgatttt atctctgatc caatcaattg gagcgctaac agtctttttg ataccttccc
     8941 aaatgttagc aattgtactt ttaacattat tgaatatgtc ggaaacaata cctgttagat
     9001 tggaccaacc gcttgaaatt gcattttttc catcgtttac tttagagcta atagtgcttg
     9061 taattccatt ccaaagattc aaagcagtgt ttttgatacc gttccaaatt ccgctgatcc
     9121 acgaagatat actattccaa acactttgaa tggcactttt agctgcgttt atagcattgc
     9181 ttatactact agtcacgcta ttccagatat ttgatgctgt agagctgatt gaattccaaa
     9241 ttccacctaa ccaactagat acagttgacc aaatattttg aattactgta gcagctgctt
     9301 gtaccaagct agtgattgta ttcttgatac tgttccaaat actagaagct gttgcactaa
     9361 ttgaattcca aatatttgaa gccgtagtac taatagctgt ccatatacca ttccaccatg
     9421 ccactactgg atcaaatata gtatggaatg tagttacaat tccattccaa gcgatgctta
     9481 cccattgtgt catagtatcc caagtgtttt taaggaaatc agaaataggt gtccaaacag
     9541 cttgccaagc tgcgcctaat aactgtccag ctacatcaaa aatacccacg ataatattaa
     9601 taccggcttg aatcaatgac gttattaagg tccatggtat ttgaacaatt cctacaatgt
     9661 ctgcccaaat aatcgaccat acttctttga ctccgttcca aatatttgaa acccaatcaa
     9721 cgaatgcttg ccaagtctct tggactcctt gccagatgtt ggaagctcct tcaactaatc
     9781 cgctccatag ctctccaaac caatcagaaa ctccttgcca aatatcttga acccaatcta
     9841 caaatccaga ccaggtttct ttaactccat cccaaactga tgaggcacct tcttttatac
     9901 tttcccaagt accacccaac caatcagtga atttactcca tattccctta aaccagtcag
     9961 taattgcgcc ccagtttttt ataattgcta taactccagc aataacagta ataactgctc
    10021 ctattattaa tgtagtagga ccacctagag ccatgaagcc aactattatt ggcattaata
    10081 aagtaaatgc agcagtcaat ccgccaatcg ctacggcata atcctgtact ggttgtggaa
    10141 gattattaaa cgcatcagcc atctttccta gaaaatcaat tactggttcg agtgcatcta
    10201 tgattgtgtt gcctatagga gctaatgaat cctttaattc agctattttt ccgtttaatt
    10261 cttgtaacgg agtagtagaa tcttcattca ttttttgtgc agatccacta acatcatcaa
    10321 atgtatggtt aacatcagtc aaagattgga caactttcat cgcgttatct tcgccaagtg
    10381 cagaccaaat tgtagaagct ttatttaatt ggtcgtattg accatccata ttgctaaaat
    10441 cttgaatcat ggaattaata acgtcttttt gtgttcctcc gccatttttc cactcttcaa
    10501 aagcttttct agtactttca ctaaacatat ccatgttttg ctcaaatcga ccatctgtta
    10561 acgatattcc catttcctta actaagtcat tgactttatc aaggttataa gcacccgcat
    10621 ctaaaccatt ttgaagcatt ccgaacgttt catcagctga atatcccatt tgactccata
    10681 attggctata ttctgccata ttgtcgccta attcgtgcgt tttatctaaa ccgttttgag
    10741 tacccgaaac cattaaatcc attgcatctt gagcgctcaa gccgaaattg accattaagc
    10801 catttacacc acgtaacgtt tcatccatat cagcgcccat ggtgttttct aggaccatag
    10861 cttgttccgt gatattttgt aaatcttgat tatttaaatc gcctaaatta cgctttacca
    10921 aaatcaatgc atctgtggac tgatctaacg attctccaaa acctttataa taaatgtctc
    10981 tggctacatt cgttaattct tcagcctctt gtttagtcaa accaaaatta gcttgtattt
    11041 tactctggga actacctaca ctattagcag agtccactgc ttgtttccct aattctgtaa
    11101 gcttatcgcc aatgtcgctt aaaacgtcag aagcttccat tagattattc atatctattt
    11161 tgcttccgat atcgtccaag ttagttgtat ctacattttt agcagcttgt cctaactctt
    11221 caaattcacg ttcagcatca ttaagcttcg cctccatctg cattgcttct gtggatgtag
    11281 cgccaaactc agactgtgta gcttctaact gtcgtctcag gatatctatc gttttctctg
    11341 cattttcaga ttgttgagaa acatattctt gggctttcgc taatttctcg gattcagaag
    11401 ctgattgacc agcagttgct tgccattttt tgtattcgga ttcaatcaga gaagcactag
    11461 cttgaacatt tttttgttca ctatccaact gttgcattgt agactcgtac gtctgtattt
    11521 cgccttttgc ttgagctagt gcattactcg ttttatcaat ttcgtttgac aaacgttgtt
    11581 gcgctgtttg ttggttaatc agttctctct caagtttctg aacttcggtg gaattttctc
    11641 cataatattt tttggcattg gctaaacgtt ggctagttac ttcaactttt tgactttgta
    11701 attcatactg cttttctaaa gaagataatt tacttcctaa cttgtctgat tcagaaccag
    11761 tctgttgtaa ttgagcttgt tctagtttta attctgctct atttttagtt aattcagcac
    11821 tgatttcttt taacgtagat ttcaatccgt catcgttagc tatgaatgtt acttctgctt
    11881 ctgttctctt tttagccatt ttttacctcc tttctttagt ttttctggga ttggtttatt
    11941 gcatagtttt tccatccttc ataagcactc ttgttgtaag ccatttgcaa aatgtcatct
    12001 aaacagatat cgcttaaaac caaatctgaa ggcatagaaa aaacgtcggt caacatcgaa
    12061 tagacatcga cccacgtttc aactaagagc tttggcattt ttacttttga agcttttttt
    12121 ccttatttgc tttttcaaat tctttttgat aagcatcgcg tgcttgtttg aacatcatca
    12181 attgataaat atagctggca gtagccatat caaaatccca tttatcgata aattcatcga
    12241 atgaaatata atcagtcatg ttcgcttggc ggtaagcaat atacacagcc tttgcacctt
    12301 gaataacaga aatatccatg gatccttttc ccacagtcat ttttgcaaac tcgtctgtgt
    12361 taaaatctct attgatcatc aataatttct tgatattcag tttaggttct aaattcaaaa
    12421 ttgttccatc gtttagttca atttttgagt aatcttcgtt catttcgcta cctccgtttt
    12481 ttttactgtg attgagtggc cgtagttgtc acaactgaag tttttttaat cacatcagca
    12541 gatagattcg tcatccattg atctgttaag tcttcttcaa gttctgcaac aattgcttca
    12601 tgataaaatt taccaaattc atcttgcata acttttgttt ctagttctaa cgcagctact
    12661 tcatccgcac cattttcaat agagaatgtt aatcctgtat tcgaagtgca tgctaacata
    12721 ccaatcagct tatttttttc ttcgaaatca tccacgatct ctgcagcaag agagaaatct
    12781 tcccctacgg aatcaggacc ataagagtaa attcccgatt taatacgttc atcttgtttc
    12841 aacccattga agcgtcgata aacttccatc ggtacatgtg cagtaattgt taccgtcata
    12901 ttgattggtt tagatttcga ttttacttct gttgaaccgc atttttttac aattctctgc
    12961 atttctgttt cgccatctaa ttgtccatta caatcagttg aaattgcatt tgttgcattc
    13021 ttaaaattaa aagaaattct tttaatactt atattgtcaa aagttgttac tgttgttgtt
    13081 ttagccattg ttgttcctcc tatttattta atttatcgaa ttgacgaatc agaagttctg
    13141 taattggatc aagtgcaaga cctaatcctc ttctcataaa ttcgtccggc tgatttcttt
    13201 tagaagtacc tatccccaaa tcaggatatt ttaaatactc aaattttctt gtaggtctaa
    13261 tgatgaaacc caaattaatg tattgagtct taagtggacg actatttttt gcgtgttggt
    13321 gccctcttct taaatctgct tcagaaacag gaattttttc tgtaatccta tccactgcaa
    13381 tagccgaacc ttttgatttc aatgcttcgt taatcagtcg ttcgctctcg cttgaatagc
    13441 gttccatccg cacaagaagt tcatcatgtc catttatttt tagctcccaa ctatttttag
    13501 ccatgacaat cactcttcaa taatcgtcta aacgtaaata ccaattgatc gatatagcga
    13561 tcttggttct ctagttttaa atgattggga tccattctct gaaaacgaat cgaacgattt
    13621 tgaatcaatg aaataatatc tagtgaatct cctgttaaat cttctctatt ttctgaatag
    13681 aaagttagat atagattttg acccacgcta tattttggct cagtgatcat ttctatttct
    13741 cctgtttcga gaatgaagta attaaaatca tcaggtagct catcctcgcc tacggagtct
    13801 tgaaagagtt tgaggccaaa atgctcttct aaggaagttt tgatagcaga aatttgctta
    13861 tttaaacgtt ctttttcttt agaattatca atcaccatat tcacccacac tttcaagata
    13921 aaaatagata taaaaattat cgtaatcggc atagataacg ttgtaacgca tactatcgat
    13981 tacgataaaa tattgatctt tattaaattt cttggcgatt ggatgaaatg gagtctttac
    14041 tttcttagtt aatttcgatc ccatcgcatc catagctgtt atatcactat ctctcatgga
    14101 aagatttcta aattttaaag aagtgatttc tgtatcttct acaccaatct tttttcctag
    14161 ttcatttctt ttggtagttt gcgtcaaaat ctttaaccaa ccatcgttga atgtttcttc
    14221 gagtctacga ttattcgcca ttcacatcac ctgcaatata ttcttgtagc gcataatgtt
    14281 gaatgaaacc taataactca ctagcgaaat tttgttcaaa ctcatctaaa gcacgattcc
    14341 agtcgtatct acatctttcg attagcaatc cgtattctaa gctttcagga gaaaaagaaa
    14401 gtgttgtact cactttactt tgaagataaa cagcattttt agctatcatc tttttaattg
    14461 actcatcttc ttcgttccag gtaacgtaaa tattatcctt cacagctatt agcaattctt
    14521 cagtcacttg ttcaggcgtc atctaaccac cgccttaatt gctttaacat atgcgtaaga
    14581 gcattttttc ttgtttacaa atgataaatc ttcatcaaaa ggcgtagaag tcacgtatct
    14641 ccctttgaaa aataaatctt catcgtttgt tgttactcca gcattgtgta agatttttac
    14701 ttctttaact ttttctattg gatcagtagc aaaacaaaag tctaattcct cgtgaacttt
    14761 aggaccaata ttgaaataca tcatgttcca aagctgtgcc cacatctcgg ctgtccagat
    14821 ttttatattt gttttttgcc ctctaaggta gcgatatagc cgattagaat ccagataaac
    14881 ctttttccaa taattcgctt tagggcggtt aataacccac tgtgcgcctc ctgaattagt
    14941 gtttatagtt tccaaagatt ctactgtaac atttacaatg tttgccatat cttttagaat
    15001 attttctccg ttttcacagc ttctaatata atcaagactt agataactac agcagtcgct
    15061 acaataccaa acatcatctt tagaaggcaa tttgcgcaaa ttaattcttt tattgaaaat
    15121 gacatccgaa tcgatataga aatatcggtc gtcctcacgc gaatgatctt cttctaaata
    15181 tttccaccat aaatatggtt taatcgaagg aatatactct ttgtcgtccc gcagatcatc
    15241 gtacacatga acttcaacac catattcctt ctcaaaaaaa ataggaatct gatcatcgtg
    15301 tctgctgaaa agcaatacga tatctttgat tcctagtttc ttcagattag ttaaacaaac
    15361 ttcaagctcc catttaaacc gattgattgc cggctgacaa agaatatact tcattctgat
    15421 cacctacgct tgtgttgtag ttgttgtggt tgttggtttt gtagttgtag tagtagttcc
    15481 caaagcgcta atatctaata caatgaaact atcgttacgt ttaggttgac cgtttgcata
    15541 ttgtttagct agataaatgc gttcgtcttc aacaaaatgg tattcatctg aagcttcaat
    15601 ttttagtgta gatcctacac ccatgaagta atctgaggct accccaataa ctgcttttcc
    15661 ttctggcaca gccgttgact gcaaatctga aactggtact ggcaatactt gtacgtattc
    15721 tccattagca gttagtacag tcttagctgg gaatacttta gaccagtaat cagttggatt
    15781 cacaattagg accacatcag aaggattcac attacgataa atcggatcat tcacaccttc
    15841 gatattgaat tttgatagtc gcgccatcaa accgcccata gttacagcat ctaaagctgt
    15901 aataggttct gctttttttt cagcatattc tccgctagtt tgtttgctca tgtcacgcat
    15961 cattccgact ggcatatctt taccagtacc atcaacaatt gcttgttcta atgcaattct
    16021 caatgattct actaaaacag tacggacata acgatctaac catactggac ctaaatcaag
    16081 cattgcctta catacaggaa tataacctga tagcttgaac tgcttcatgt taattacatc
    16141 aaagccatta tctaaaactt ttttaacagc ttcgcaaagt ttaccccacc atgctggatt
    16201 gactccacgt gacacaatcc attctgttac accagttgtg ttaacaaaag taattttttg
    16261 caatagtgga tgagattgtt ctaaatcttc aaatacacgt tcaaatacag tagctggcac
    16321 taattcttcg acccctgcaa aaccttcgtt tttcactact tcgttataga attttgtttc
    16381 ttgtgtagtt aatacacgct gaccacggtt cattaatact aattgatctt gattttttgc
    16441 tgttgcttct tctaaaattt tatcctgaat ttccttagat aagcttacca tagctgcgct
    16501 aaaagattct tcgttaccat ctttaaaagc tttcatcaat tggtcgcttg cagctgttac
    16561 accttttaaa tttttaactg tcattatttt acatctcctt gtccaaatgt tttatttaat
    16621 gctgctgtaa atgcagcaat tttttctgct cttttttctt taacgtcatt caaaatttct
    16681 tcaacgcttt gttctttttt agcttcagta cctgagctat tttctgcatc gataatttca
    16741 tcgaccaatc cataactcaa agctgtttct gcatccataa acgattcttt ttcaagaagt
    16801 tcttgcaatg cttcatctgt gccattgaat cgtgttttat atgaagcctt taccgattta
    16861 tcaattgatt ccagttggtc agcaatcgta cggaagtcat cgacatttcc ttctccgtat
    16921 gtggaagcgc ggtgaatcat caattgtgca ttgttgtaga tttttatagt atcgccagcc
    16981 attgcgataa ttgaagcagc actagcggct aagccgttaa tcacaacgtt aacttttgct
    17041 ttatttgact taagtaagtt cccaatagca atcccttgaa atacgtctcc accgtttgaa
    17101 ttaattacta cttcaatttc ttcttgatca cctagactat ccaaaatatt tttgattccc
    17161 ttgtcagtat tcccttcaaa gaaccaacta gaaccaataa atccctgaat aaaaatttgc
    17221 ggtactgcgc cttcattctt tactgctaga aatgttttca ttgtcgtcat tcgcctcacc
    17281 tcctttcgat acttgttgat tgtttttagt tataaatatt tcatctgcca tcgccttatc
    17341 agagcgatca tttccaacgc gctctcttcc ttcgttgatt gtaaatactc catttctaat
    17401 gcctacatca atagcgtcaa ccaaatcttt gaagctagta atcttgatca tagttgtatc
    17461 cacacgtaca aaattccctg acaagtattc ttctacttca tagagactag cgttaaacgc
    17521 atcctgaata agttcagcaa tcggtatgat ttcgaacatt aaaaaagcgt ccacttgatc
    17581 cgataaccca ctcatgtctc cctttagtag gtttttcgga acgtgaaacg ctgctgctgt
    17641 catctcaaag atgtcgtcta ttaagttttt tatatctctt gaattgcttt ggaagtttcc
    17701 gctgaaatct tctaatgtgt actcattttg taattgaaat accgcacctg cattatcagc
    17761 ttccataaaa gccttaaatt gtgatgtcat cattttattg atttgatctt gtgttgtatt
    17821 gtcttgcggt cggaataaat tccctttcag tacgtatcta cgagcgttag agcgcttgta
    17881 aacattcatg gcactagaaa tgagtttccc atacgcttga taatacgcat cgactagttg
    17941 cctaatttgt tgatctgcgt attttatata gataacatca ctttctagaa attctctatc
    18001 aaggactatg ttgttaattt gcacttgaga aaacacatca tctttcaatg catattctgt
    18061 gacatcccaa ctatccgcaa taaatatttc gctagaatta ttagacggag aaacgatcaa
    18121 tacttcattg tagaatatta atctcctgat cagttttttt ctaaattctg ttgcattatt
    18181 tttcttatta ggagctacat tcagcctata gtaaagatca ttctttttat tttttccatc
    18241 ttcatatgac ttgaattccg ctttactcat cgcatttgca atcaaatcaa tacaagtttc
    18301 aatcgcaaat tttcgataca caaaatcaac ttgcaattta caaaagtatt cttctaaagg
    18361 aaccgttgct ttttttgtga agtatcctac cgccttttga aaaatcccca ctttctcacc
    18421 tcctttcaag ttagaatact agaggagtaa atccagttcc tgtattttct actgagctat
    18481 ttgtgactgt tacaggagca gaatcataaa tatcatctaa aaaattcaaa ccatgaagga
    18541 atgaaaaaaa gccatccgtt tttctagttt caggttctat tttttcatag cgtatatttc
    18601 cattagaaat atgctcttca tatacattca tgcaatacca acgcataatc gcatcgtcac
    18661 caaaaaataa acgttgatta ataaaaaggt catcaaccag atcttttaac ataccatgtg
    18721 taacagatcc gcttcgaaca atttccacag taaaacctgc ttcttctaaa gcgggcttca
    18781 atatttttgc acggtacata tccatagcga tttttttaat ataatattta ttactcattt
    18841 caagaaacca acctacaata taatcagctt ctatattttt tccatgaacg atctgtgatt
    18901 ttccttgatc tatagaaata tctataacct ctcgtttgat gttttgtaat cgaagggctg
    18961 attcgtggat aaaagtatgt tgtgtaaaat aaacatcttt atcgtatttt cctagcaacc
    19021 caacgctggc aaaatctcgt ctatcagcaa aatcgactgt tcctatcact tcatccattt
    19081 tttcaggaaa ttctttttct ttcgtatgca gaacatcatc atatgaagca acagcaaatc
    19141 gtgtatcttc cataggtctg ttcattcgtt tggtcatgaa cgtaagtctt aaaccagcat
    19201 tacgttgcat ttgagagtat tcttgaaaca ttttccgttt taaatctgca ttgtaattaa
    19261 tagttggaca agctttttcc cacatgtcgg gatcatcaac ttcattatcg ttatccaagc
    19321 gacaaataaa tggaaacaaa ctagaaaatt ctgctccatc cttgtcaatt ccaagttctc
    19381 cagaaagaat catttttgat tcttctataa tgtcatcaag cggaccacca cgaacatgac
    19441 cattagttgt atcataaaat tctctataat ctcgaatttt accaccacca gaagtagcca
    19501 catttatcat tgaataatct tcattttcgt gaatttcatc aaagcggttt gcacctggtc
    19561 gcttcccatc ttttgttcta gcatttgccg tgttataacg aagtttgctg tttgtagcga
    19621 tattttgaat aacttccttc gtagctttaa atactttttt atctaaatca ggatgatctt
    19681 taattacttt aaatacatca tcaaaactag tctttgcttg gctttcatta ttggcataga
    19741 tatcaatatc ataattttta ataccgtgtt tagcggttag tagaaagaag ttgttccaag
    19801 aagcaaaacc agttttacca ttaccacgtc ccattaatga aagatatcta ttgaacacta
    19861 gtgttttatc ttttttccat cgaacaccat aaataaaaca ttgtagaaat ttttcccacg
    19921 gaattaattc gaatggaaag tattgtgctg gtatattgat tgaatcctct accatctgct
    19981 tatcgaagta aatatcttct ctagtaaaga ctctttcttc tagataattt tttagcaata
    20041 attgctcttt gcataccttg atagtgcctt cttctatagc tttgaaccaa ttttcaatat
    20101 gcttataact caggaattga ttcatttgct tcacctacca attcaggagt aatggcaagt
    20161 ttatccaaca tcaatcccat ttgtttgttg acagaaacaa gcaacgctac tgattcattc
    20221 tttttaccat tctccagtct aatgccgttc tcggatatat cttcttccag tgatatcgcc
    20281 gtttcccata aactgatata acgatcaaca ttatctaaga atggctcaat atttgttttc
    20341 tgactttcca attggcttat taaagagcgg cgtaattttt ctctgtagcg attttgagac
    20401 aattcgtttt taaacatttt agccctcctt tcatgataaa gttcgaaaaa atctcttttc
    20461 ctgacagccc cctccgtttc atcaccccca aaaaatttgc gatttatttt aagggggggt
    20521 tatctcacca tcggaatgaa agcttcagcg aagtcaatgt aataattaat ctcttcaata
    20581 ctatatccaa aaacattttt tattctttcg acgttattat ctttattcaa cgcttctctt
    20641 acttgattca ctttgtattt actacaacag ttatctgata acagatccct aatacctaca
    20701 tagcgaacgt atatcaaacg tttaattaat ccctgagtat aagatgaata ctcttcaatc
    20761 ttttctgtat catactctct gccattgtca ttgatgatca tgcacttacc acctttcact
    20821 tgcatcgaag ttagcgaagc tttctatctt cttctcttgt ttatctaacg ctgtaagata
    20881 tctgccatga acttcattat gatgttcaac acataaacaa ataagattat ctaaatctaa
    20941 agctaagtca ggtctatcct tgacttcctt tatatgatga acgttctcta ctctatgata
    21001 cttacctagt cttctacact cttggcattc atagtgatct cgtttcatcg ctttctctct
    21061 aagcctgcgc catttaggag actgatagaa cttaaccaaa cgatcttctc ttatcaactg
    21121 taataaccat ctatagaatt cctcggtcat gtcccatctc ctttcgcaat cttatttaat
    21181 acttagctat tcttttgcca tacaatggaa taacttcatt gctttccttc cgtttatatg
    21241 tatcgctctt tattggtctt ctatactttc gtactatctc accgttaccg ttttgcacag
    21301 tgattacttc atgcttctgt tctaagtatt gtggtctata catcgtcgtg cctcctttac
    21361 gcaaaataaa aagaccactc aaagagtgat ctacgaattt taaaaaatct catactgaaa
    21421 tcttattttt aatgtcttta tataagttcg agcctcgcaa aacataaata tcttgataat
    21481 attctttgcc attatattct aagaataaaa aggaaaattt caatttttta cattttttat
    21541 atctcttttc taatttcttg ctgttcttta tgttagctac cattgcagta actaaacttt
    21601 catttacaat tggtattttt agaccttttt ctaagtatcc aatattctgg aattcttgat
    21661 taataaggtc tgttggattg agataagata tttcgtggtc cacatatttt tcaataagct
    21721 ttttaactac agggtatttg taaatatatt tgtaccaatg ctttctgata aaacgttgga
    21781 aaatgttata tttacctata atcccgcaaa actttattgc ggtttcagat ttcccttcat
    21841 ttaataaagt tatagtaaac ccatatttac cgacgacagt aatatctttt ttggttattc
    21901 cttcagttat tcttgataca attttagaac tattagaata ccagtagtac tttgatgttt
    21961 gttgaattgt aatcactatc aaaataatac ctacccattc gcctaacgta ccatatccat
    22021 caaatgtaaa cccaagaaat ttaactacgc ccaccatttt ctatcacctc agaaataata
    22081 ttatcaaata atcttagata actaaacagg ggacttgtaa atttcagata attactcatt
    22141 gacttttccc attcatcctt tattgcgtct accctttccg ccacagcgac aaattgatat
    22201 tgtgaaattt tatacatagc ttataatttt aattatcagc gagtggtccg ctgaaataaa
    22261 ttataggtgg tgaaaaattt gtactttgtt ataagagaag caactaatgg ccaatattac
    22321 ttcgttatta agtccaataa caatgaagta gtagcaacta gcgaaacata cttgactaaa
    22381 tattccgctg aacaaaccat taattctata aaaaacggaa tcaccaaaga ctctcaagtt
    22441 atcgatatga ctaaataaga cgactaactt catttgctag ggagttcatt tcagctgctt
    22501 tttctaccaa agcagttgag atactttcta gcttttctga tttaacagaa ttaaatactg
    22561 gcgtcttgat actaatcgat acatcttgac gagaatcagg actcgttgct ctattttttt
    22621 gcaccactga tctgtacttt tctactgaat gatactcaat tacttgttcc aaatgttttt
    22681 tgtactcttt acatacagct tctttttgga tcaattctaa acgttgttgc tcaataatat
    22741 caatcaaccg ttcccgatcc ataccttgat actttatttg ttcgacttcc attcatttcc
    22801 cctccaatac ataaattaat tagctaattg ttgctcattg atctggagag ctatttcttc
    22861 ttctataagc tcaacgatct tcctttttgt cgaatttaat tcgaacttat gatccattaa
    22921 agtaagcttt atgttcttaa tcttttcacc ttcgaattct ttgataatat cttcgattct
    22981 ttggtttact aaaattgtta gttgatcaat tttttcggaa gcgatcttca ttttatatac
    23041 cctccaatac ataaattaat agacagcaac ggatgataga taataagaac aatttagaag
    23101 gagttgaaat tcacatcctt attcttaata tttccgctgc tgcctatcga agcttaatta
    23161 aacgatgagg gagatttcct cccttacatt ttattttgtc gatcctgttt cctaatcttt
    23221 cgacactatc ataatacaac gttgaatagg taagtgattg gtataaaaaa ggtataaaat
    23281 ggaaaccaaa ttggtaataa aagggtataa aaagtgtaaa aactggctac ttgaaagcaa
    23341 ccagttctaa cgatgaagca aattggatga taattctgtt tgattctact ttaaccgatt
    23401 cttcgctagt attattcctt tgagcagtta cataaatggg cagaccattg atataacgat
    23461 catagaatat cttcttgcgc ctttcagtca catcaggctt atgcggatgc tgtatcgctg
    23521 aatagcctcg aacaaacaat ttatgcagat actcaaattc ttcctgtgct tcttctttat
    23581 cgatcagcat tctttctgct tcaaatatat gatcagctgt agaaggtgga accaaggaat
    23641 aagatgctgt cacttttggt tctcgaggtt gccctactct acatctagct gatagatatg
    23701 ctgaaagaaa cacagcgaca ttatgttttg tgcgttccat atcaacatct ttcgcgcttg
    23761 gtgtctcata tttctttaca tcgaaaagta ccatcctctg attcccccaa ttatgatata
    23821 atacttatgt cggaaatatt attcatagtc ggaggaatcc gacttttttt attttgtacg
    23881 tgaaatgagt tctcctgatt tatacgcctc agcaaattca accaaagcta ctgccttcat
    23941 tctgtctttt tctctatccc acgctctaaa cttcggtatc attcgctgtc ctcctcgtat
    24001 ttttcaatca attccattac ttttttcact atttcaaact caaccgcttt tgattcttcg
    24061 aaatcatgaa caatttctgg aaacagtaca tcatcaacta cccacaaaat aatctggcgc
    24121 tttccaccaa aatttatgat tagatggtcc gattccacag atagtgttgc tcctgattcg
    24181 atatcatata aatccatgct gaattgaacg agttttttta tcatttgctg tcctcctcaa
    24241 atactcttct aatatttctt tatacttctc tacaaatttg aaacgatctt gatgaagttt
    24301 cttgctccaa tttgtttgcc gatccagctc acgcatctga tcgaaccctt tttgaatttc
    24361 gttgtaataa aattcaatgt ttgctgctgc tttccaatgc ctgctacttc gcactcctgc
    24421 tcctgtttca gccatttcta acttaactaa ttcagctcgt tcttttgatt ttttgtcttt
    24481 ctgaatcttc atcatgattt tcttgaggat gatgtcactg tattgtgtaa tgagatccat
    24541 tatctctcct ccacatacct aaactgtcgt ccttttgaat caatccataa gctcctagct
    24601 ctatcccaga taatgttttt gcttaatcca gtaatttcag ataactgttc agctgtacct
    24661 gttactagaa ttcgatcacc atgccagatt gcaatttttc tcggcgtttt ccgtttaggc
    24721 ttttcagtcc acattgattt accgagcttt tggacttctg caactatttc tttgtcttcc
    24781 tgccaagatt ctgacttggt taattcagca attcgtttca ttgtcgcttt cttatccacg
    24841 ctcattcctc caatctacga atttcccttc ttaagttctc tatgtgcaaa tcgattgcct
    24901 ttctcgccgt ttcattgacc atcactgcct ttgttcgttc tagatcgtca atttcacgct
    24961 gaatgtttcg aatacgcatt tgaatcactt cttctgttgt catgatggac cacctcgtta
    25021 aaaacgctct tccttgaacg tattccgata ttttttagct aatatcaacg gcgcttgata
    25081 ttgatgacag aacaactttg ccttgatctt aaagtctttt gtctgcattc ctttgacatc
    25141 tacgactttg acaagtttgc cgtttttata aaatgtgaag tcgggaatat actcgatctt
    25201 gcgatacttc tttccgtcta gttcaaattt cggcatcagc tcaaatcttt cctgaagttt
    25261 tactttccag ccatttgctt cagcttgcca caaggctaga tcgtaatact ctgcttctgc
    25321 gatagaatca aacttgatac ctcgatgaac agttttttta ttacggtatt tattcatgcg
    25381 atactacctt tcactggttt tatgcgcttg tctgctgttt gttggaattt cagcgcataa
    25441 ccttctgaat tcttaaatat cctagaaaca attctttcac cgtaggcttc tcttagttca
    25501 ggaccagata agtttgttgt gatgatcgtt gccttgttct gtctggcttc taagagcgtg
    25561 tttaacgtgt tgtttgtaaa ctgcctacta tttgataccc cactacctaa ttcagctcca
    25621 atatcgtcaa aaaccaccaa atcagttgtt ttaatatcgg ctataagcga tccttcaatt
    25681 tcttttctca gttcagtatt gttataagaa aactttattt gctctaataa ttcttgatag
    25741 cttataaaaa gtattttctt gtcataattt gagcgctcaa gtatttccca agctgtggcc
    25801 attgataagt ggctttttcc gcttcctgat ttccctgata gaatgaaatg tgcaggatgg
    25861 ttcagcagaa cctcattcgt atagcttttt gctttttcta aagcgatttt tgtttcttga
    25921 tccactacgt gataattttc cattttgcat ttaaacaaag ttttatctgt taataccgaa
    25981 ccattttgaa aaaaactcaa cgctcgtgct tttaagctat cgttatatat ccgttcggtc
    26041 tgtatatcct ctttcacacg taacgcttta taaccacaac tcatgcatgt tggtttacaa
    26101 cgttctgaac catccttatt tttagctcgc caactataca aaggttcgct acattctgga
    26161 cattttccgc tttgcactaa tactcttctt attagtttct ccatagcatt tgctaggctt
    26221 tccatgtgat gcatctcctt tttaaattgg caagtcgtca tattcactag gattgctgta
    26281 ctgtagtttt tgactttgct ttttatgatt cttcttgtct gctttgattt cgaatttgag
    26341 cttctcaaat ttttctctca atttcttagc acttctaata tttccaaacc aaaattcatt
    26401 tgtaggtagc caattgatca catactcaat cgcttctata gatgctttat ctctttcttc
    26461 catcaacctg attgtgtctg cccatttttc gatatctact ttgttcattt cttttggaaa
    26521 atcttcagtt aaattacttt gcaacttttt agcaaggcgt aagtgttcgt cagaatactt
    26581 acctttcttt tcttctttat ctatatcttt atcttcttct atatctttat ctgtaccgtc
    26641 acgtgacgtc acgctaacgt cattttccaa tttgagacgt tcctgtctct ttctttccct
    26701 gtatttacgg tttctttcag cattttttag ccttacttta tccataccct cgatattttg
    26761 atgtttttcc caattactga tggcaattag tccatcactg cttagatcaa tcatgttgaa
    26821 atttgccaat gtagttagcg ctaagcgaac cgtatttacg tttttgccaa acaatgtagc
    26881 aagcatttct tcggtataag gcatgttcct ctggatatat atcagaccat cgtcgttagt
    26941 ctttcctgct aaaactagta atcgaatcca tataacgatg atggcatccg actcaggaac
    27001 agcttggatt aatcgtattt tttcatcgtc aaacatagta gttttaagtt tgatccaact
    27061 tatctcagcc aaatttatcc tcctatcctt aactttttaa ttgtttcctg gtttaacttg
    27121 atccctttga tttgatattt atttttgaaa ttgatcacac ctattttgtg tttctctgtg
    27181 tgatggattc tgcagagtgc tgcaaatgtg tactctgaat gatcaacttc tttgcgcttt
    27241 cgtcttccca gcgctttgtc aaagtgatcg atatcagctc ctgttttgcc acagatgcag
    27301 cagactcttt ttgtaatgca tttgtagaag taatactctt gattcgctgg taaaatctca
    27361 tatccttctt tgaaaggaat atgatgttca aagatgaaat ctaggatgat attcgctaag
    27421 atattggcat cactcacggt tgtattcgat tcgtctttga ggcttatttc gcgccctgtg
    27481 acaccttcaa aacggaagta gaagaattcc ttccagaagt ccgttggcat gcctgtatcg
    27541 atgaaaatat cgcctatgag cgcatagatg aagtttcttt gctgtactgt gaaccgtcgt
    27601 ggatcaataa agcgaatttc aatgactcga tcgccatcat atccgtcata catcgttttc
    27661 agccgttcga tatttacttc ttcgttgatt gttgcaccaa tgtcgttacc tttaaatttc
    27721 tttagtaccg ccgagtatga atctattagt ggtttaaaca ctcatatcac ttctcttttg
    27781 tttcttctct gtactgatct tcaagccaat taacgcctcg ttttagaatg cccaagtctc
    27841 tcttggtcca tttactgtca tcagcggtta tggaagctgc atcagtcaat gcaacaattg
    27901 cttcatcaat tgatttttcg tacttgttag caaccagttg taaattcgat ttgccccaat
    27961 caggatcggc caaatattga tctagagtgg aaagttcatt ttccatatgt taaaatctcc
    28021 ttagttatga ttttttgagt gactcattgc tttggtcggc ggagtcactt ttttatttgt
    28081 tgccatgctt ttttcttttc gatatgttgc ttgcttaaaa taatagaacg gctatttgcc
    28141 caccaattat cagcaatcac tttaccgatt tttagcgctt cttctcgtgc catagttgct
    28201 cctttctttt gagtcaagca gattgattaa aaccatcaat gctgcgaaca agcttcctcc
    28261 gataatactt tggtgcgcta caatcactaa taaccccaaa atgaatccta taaaaagtgt
    28321 gtctgtcttc ttcataatct aatctcccta ttttttattt ctagcattct caaatcctca
    28381 agttcagaag caattagttc agcttgtcta tctgatagct catcggattt tctaagcgct
    28441 gcacgatcat cttgtaattg ttttctacgc tgtttaatca gacctagaat ttgatgttct
    28501 tgttgcaatg tgtaggacat aaaatcattc tcctttgcct ttagaactca aagttttctt
    28561 tcaaaaatct ttggagttcc gatcgttcaa ttctgatgtc taacttgctc cactgctgtg
    28621 tttttaagcc taggcttatc caatgtgtta atttgtcatc accaatgcct aaaacttttt
    28681 ttacctctga tttgtttgga tatggaggaa gctctactga tttgttcata aggtgtaatc
    28741 gttcgtccaa tgaattaaga acagcattcg taatctgtgt agttaattcg gaaactacta
    28801 aattatctgg aattgttatt tgcatgttat ttctccttct ctaactctgc tagtgctgcc
    28861 tcaattggct tgatttgttt atctggtttt ctacgcccat tcataatgtc cgacatatat
    28921 ggtctagaaa ttccgatagt atcagctaac cagttctgag actttccgta ttttgctaat
    28981 tgaattctga ctttcaaaat aaattcttgt gacatcgtca ttcctcctct aataaatcga
    29041 tttctggaat atatccttct tttttcagcg actcataaat gaacagacgc cctttttgag
    29101 tccattttgt attcatcaca acttttgttc cgccatcaga tttcggaatc tcagttgtat
    29161 gagattttgt gtaaccctgt ctcatgtgtt ttttgcataa taaccattgg ttgcctactt
    29221 ttttctgaat acctagctta tgaagtagtt tgttcatctg ttgtggagac atcccataat
    29281 cagccgcgat ttgactaata gttactgaat ctgtagaaga taagatacta tccaaatacg
    29341 aaattttggg ttcgtattct gcaatttttt gttctgcgat tagtcttcca gtacgttctt
    29401 ctttcaactt agttgctaat tggatgattg tatctggatt aagcaaagct tcttctactt
    29461 tttctggagt tagataacct ccatgttttc taattgctgg caacacttcg ctagtcaccc
    29521 aacgtttaaa tttcttagca tttggttgtt tgcttcctaa aattaaggag tacaaacctg
    29581 attcgttaat aatagttaac cctctaggcg attcaaaagt accgttttgg tagttttgcc
    29641 gatcttctac atcgacgtgt ctgttaatat ctctactacc attttggtac cctagaactt
    29701 tagccacatc ttttccaaca aaaaatggtt catcatgtat tgttactgtt cttacttcat
    29761 gttgttcaaa gttaaaaatt tgcggtgtgt tcatttttgc tcattccttt ctttgatata
    29821 attttgaata gaaagcgagg tgaaaatagt atggaagaat ttaatatgga tgtcgacgcc
    29881 ttattcaaac aaaccgtatt caagactgtt aataaagaat tcaaaataga cttccaaaat
    29941 gacgaatctt ttccaacaga aattgaatta ttcgaagaac tttctcagag cgtttctgag
    30001 tctttttctc gtcagttgca aaagaatttt tttgatgctc ttgtggatga atttcatcaa
    30061 caacagcact aaacttttgg tctttaaaat ttaaagttat taaagctcct tttgcggaag
    30121 gagttttttt attttgtttc atgatgtttc ctccttttct ttaaatatgt aagctaataa
    30181 aattagctaa tttttattga catttctatc caactgtctt atatttatat acagttaaat
    30241 aagcctagaa aaaccctaaa aattaacatt cttagtttgc cgacctcgaa ttcgtttatt
    30301 ttattaggtg tatttcttgt tgcttgttag cttattaaat tagcttacga gttaaatata
    30361 agacaattgg atagatttgt caactacctt tctatctttt tgtataaatt attatcgtac
    30421 gctctaggaa ggttgatttg acatgctttt cgaaagggtt aaagagctct gtaaaaaaag
    30481 aggtatttct atttctgaat tagaaaatag aataggattt ggaaaaaact ctatttataa
    30541 atggaagaca caaagtccta aaatagaaac tttgcaaaaa gttgctgact acttccatgt
    30601 atcaacagat tatttgctag gacgcacaga tgatcctaac gcgggagttg caccagagga
    30661 aagaaaacta accgtggaag aagctttagc atctgttatg agtagcgacg gaaaaccgct
    30721 caccgataat gatagggaaa tactatcagc tatgattgaa gcatatttag agaaaaaaga
    30781 taactaaata agtaggtgag tcatttggac agtcaaattg aaatgataat taatgaactc
    30841 ggcgttaagg tagaagagcg tgaaaacctt gatgccgatg gccattatgt tgcttgtatg
    30901 aataccatag taataaaagc taatttatct aagtatagaa gacaaagaac cttattacat
    30961 gaattaggac acgcttctaa acatcatgat aattattttt tatataactt agcattctct
    31021 ctccattcaa aaatggaata tgaggctgat cgcttcatga ttgaaaaatt attagataga
    31081 tatattgcaa agtctgaatt agaaccacac aatatcaatt acatgaaatt tatagaagat
    31141 aacaatttaa gcgttcgctt cgaaccactt gtgaaagaat tattaaaagc tcgcatctat
    31201 tgttatgcag ctctctaaaa ttttttaagc aaaaaagaac atacgttcaa aaatagaaag
    31261 gtgaacaaaa atgatatata cagaattcaa agaatggtta gaaaaaagca caaccggata
    31321 cgaaacattt atcatcaaag ctactaatta tcaaattgaa aaaaacaaaa atagacccca
    31381 aaaaaaacgc tgggatgata agaaaataga taaagctgta ttagaaatgt ggaaacaagt
    31441 cgtgactaac ttgtatcaaa caattcgtaa agaaaaagga gttccattaa ttaacgggaa
    31501 ggaaatatgg cttgaattta tagaggaaca aggactgatc gaatttttca atgatagcat
    31561 ggcagaatta gaatttgaat aggggtaata ttgatggcaa tgataaaaca atataaaaag
    31621 aaaaatggcg aaaaagcatg gtactttaaa acttatctcg gtattgatcc gctaactgga
    31681 aagaaaaaat atactactaa acgaggattt agaacacaaa aagaagcaaa aacagcactt
    31741 tctaggttag aactagaatt acaaaaaaca ggaatgccca caagtacaaa tactactttc
    31801 aaagaagcag cagaattatg gctagaaagc tacaaaaaaa ctgtaaaaga aagttcatat
    31861 tcaaggacta aaataatctt taataaacat atatatccca aatttggaaa tattaagctt
    31921 tctaaaatta atacggcata ttgtcaaaag gtagtaaatg attggagtga aaaaggaact
    31981 tcaaagcagt accctctttt cataaactat atgaataaag tttttaagta tgctataaat
    32041 attggtttaa catctgataa tccaacatta aatttactta ttccaaagcc acaaattaaa
    32101 acagaaaaga aattaaaatt atatacaaaa gaacagttgg aattatttct aaatgaagta
    32161 tctcaagaac agaatccata ttttaaaaac agagactata cgctctttag actattagca
    32221 ttcagcggat gtagaatcgg cgaaatatta gcactcactt gggacaatat taattttaaa
    32281 acaaatgaaa tggccattaa aaaaactgta gctcgttcag ataaatatta tatatctgaa
    32341 actcctaaaa ccaaaaaatc aaatcgaata atttatttag atgaaaaaac tataaagcaa
    32401 ctaaaatttt ggaagctcga acaaagaaag tacttatttc aattaggatt tactaaagct
    32461 aattatttgt ttaccaatga cgaaaataat ttcacaatta atcagtcagt ggcagaaaga
    32521 tacaatatat atcgtgagcg tgccggctta ccttatatcg gtctgcatgg ttttagacat
    32581 acacatgcat caatgctata tgaggcaggc gcagatcaca aagaagtcca agaaagaatg
    32641 ggccacgcaa atataaaaac tactatggac acatatacac acattactaa cagcaaaaaa
    32701 gaagaaacaa cacaaaaact aacaaattat attaacttct aagaaagtat ggtcaaaagt
    32761 atggtcaaaa aaaatcccat aatttacaaa aaagctccat cccttgctac acaagagata
    32821 gagcagttta tt
//
LOCUS       DAPBAF010000035        32123 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.035, whole genome shotgun sequence.
ACCESSION   DAPBAF010000035 DAPBAF010000000
VERSION     DAPBAF010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 32123)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32123)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32123
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.035"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     regulatory      complement(37..139)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(145..1116)
                     /locus_tag="RD451_001875"
     CDS             complement(145..1116)
                     /locus_tag="RD451_001875"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HDT7567132.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     gene            complement(1210..2583)
                     /gene="glmU"
                     /locus_tag="RD451_001876"
     CDS             complement(1210..2583)
                     /gene="glmU"
                     /locus_tag="RD451_001876"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HDT7567133.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(3086..3904)
                     /gene="purR"
                     /locus_tag="RD451_001877"
     CDS             complement(3086..3904)
                     /gene="purR"
                     /locus_tag="RD451_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HDT7567134.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            complement(4071..4895)
                     /locus_tag="RD451_001878"
     CDS             complement(4071..4895)
                     /locus_tag="RD451_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HDT7567135.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(4868..5548)
                     /locus_tag="RD451_001879"
     CDS             complement(4868..5548)
                     /locus_tag="RD451_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HDT7567136.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(5571..6509)
                     /locus_tag="RD451_001880"
     CDS             complement(5571..6509)
                     /locus_tag="RD451_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HDT7567137.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(6754..7617)
                     /locus_tag="RD451_001881"
     CDS             complement(6754..7617)
                     /locus_tag="RD451_001881"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HDT7567138.1"
                     /translation="MGERMELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADH
                     LFFEEITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAG
                     LGGGSTDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQ
                     VLPSMPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMG
                     NSLEDITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGF
                     CEEVYLVRTLQ"
     gene            complement(7759..10332)
                     /gene="mprF"
                     /locus_tag="RD451_001882"
     CDS             complement(7759..10332)
                     /gene="mprF"
                     /locus_tag="RD451_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HDT7567139.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLS
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            10473..11279
                     /gene="proC"
                     /locus_tag="RD451_001883"
     CDS             10473..11279
                     /gene="proC"
                     /locus_tag="RD451_001883"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HDT7567140.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLIDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            complement(11358..12914)
                     /gene="rny"
                     /locus_tag="RD451_001884"
     CDS             complement(11358..12914)
                     /gene="rny"
                     /locus_tag="RD451_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HDT7567141.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(13325..14374)
                     /gene="recA"
                     /locus_tag="RD451_001885"
     CDS             complement(13325..14374)
                     /gene="recA"
                     /locus_tag="RD451_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HDT7567142.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(14483..15724)
                     /locus_tag="RD451_001886"
     CDS             complement(14483..15724)
                     /locus_tag="RD451_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HDT7567143.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(15964..16542)
                     /gene="pgsA"
                     /locus_tag="RD451_001887"
     CDS             complement(15964..16542)
                     /gene="pgsA"
                     /locus_tag="RD451_001887"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HDT7567144.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(16751..17674)
                     /locus_tag="RD451_001888"
     CDS             complement(16751..17674)
                     /locus_tag="RD451_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7567145.1"
                     /translation="MLRRIKQTGEDERVAFETIGEKLRQARLNKKISLDELQQITKIQ
                     KRYLEAIDNDDFDQLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQ
                     PETVSTSRKAMHQEESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDT
                     ASSLKVEGSVEESSSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITD
                     ATKPVTLEFTAVNRVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNA
                     TIKANGESVPVNPGENNQSPKNVNLTLQYAE"
     gene            complement(18413..19699)
                     /locus_tag="RD451_001889"
     CDS             complement(18413..19699)
                     /locus_tag="RD451_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HDT7567146.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(19692..20960)
                     /locus_tag="RD451_001890"
     CDS             complement(19692..20960)
                     /locus_tag="RD451_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HDT7567147.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYSDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            21212..21673
                     /gene="mscL"
                     /locus_tag="RD451_001891"
     CDS             21212..21673
                     /gene="mscL"
                     /locus_tag="RD451_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HDT7567148.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(21732..22178)
                     /locus_tag="RD451_001892"
     CDS             complement(21732..22178)
                     /locus_tag="RD451_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7567149.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGE
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
     gene            complement(22271..22516)
                     /locus_tag="RD451_001893"
     CDS             complement(22271..22516)
                     /locus_tag="RD451_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HDT7567150.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(22631..23209)
                     /locus_tag="RD451_001894"
     CDS             complement(22631..23209)
                     /locus_tag="RD451_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDT7567151.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSVISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(23286..23816)
                     /locus_tag="RD451_001895"
     CDS             complement(23286..23816)
                     /locus_tag="RD451_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HDT7567152.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(23820..24680)
                     /gene="rlmB"
                     /locus_tag="RD451_001896"
     CDS             complement(23820..24680)
                     /gene="rlmB"
                     /locus_tag="RD451_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HDT7567153.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(24673..25068)
                     /locus_tag="RD451_001897"
     CDS             complement(24673..25068)
                     /locus_tag="RD451_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HDT7567154.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(25065..26477)
                     /locus_tag="RD451_001898"
     CDS             complement(25065..26477)
                     /locus_tag="RD451_001898"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HDT7567155.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(26474..27010)
                     /gene="cysE"
                     /locus_tag="RD451_001899"
     CDS             complement(26474..27010)
                     /gene="cysE"
                     /locus_tag="RD451_001899"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HDT7567156.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     misc_binding    complement(27096..27335)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(27332..28792)
                     /locus_tag="RD451_001900"
     CDS             complement(27332..28792)
                     /locus_tag="RD451_001900"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HDT7567157.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(28962..30119)
                     /locus_tag="RD451_001901"
     CDS             complement(28962..30119)
                     /locus_tag="RD451_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HDT7567158.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(30153..31523)
                     /gene="radA"
                     /locus_tag="RD451_001902"
     CDS             complement(30153..31523)
                     /gene="radA"
                     /locus_tag="RD451_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HDT7567159.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKTAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(31586..32113)
                     /locus_tag="RD451_001903"
     CDS             complement(31586..32113)
                     /locus_tag="RD451_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HDT7567160.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
BASE COUNT         8797 a         7066 c         5680 g        10580 t
ORIGIN      
        1 tcacaaagga ggaagcagct ttcgaaaata gtcaaacagc tgtttattca caattcctac
       61 gctcgcataa ccgatacagg tacgaagggt ttagaaatag attcaatctc agcccaattg
      121 gactcccctt tgtgagttta tttattattt attttttgtt tcaaacaatg gactaactgg
      181 tttgttttca tggatacgtt tgattgcatc tcccattagt ccgccaacac ttacttcatc
      241 gattttgtcg attttacgat cttctggaag atagatcgag tctgtaacaa ctagacgctc
      301 gatagctgaa tcttctattc tttgtaaagc agggccggat aatactggat gtgtacatga
      361 agcatacaca ctagttgcac cagcttcttt caaagcattg gcagccaatg tgatcgtacc
      421 tgctgtatcg atcatatcat cgatcagtac acaagttttg cctttgactt gtccaatgat
      481 attcattact tctgcaacat ttgcttttgg acggcgtttg tctatgatcg caatcggaga
      541 tttcaaaaat tccgctaatt tacgtgcccg tgtgacacca ccatggtctg gtgaaacaac
      601 gacaacatca tcgcctttga ttcctttttc taagaaataa ttggcaataa gtggcgcacc
      661 catcaaatga tcgactggaa tatcaaagaa accttggatt tggactgcat gaaggtccaa
      721 agtcagcatt cttgttgcac cagctttttg aatcatgttt gctactaatt tcgctgtgat
      781 tggttcccgt gcacgtgctt tacggtcttg acgcgcatag ccataataag gcatgactac
      841 gttgattgtt tttgcacttg ctcgtttcag tgcgtcaatc atgatcagca actccatcaa
      901 gttatcattg actgggctgc tcgttgattg aataacatag acatgcgatc cacgaatact
      961 ttcttcaatg tttacttgaa tttctccatc actaaattga gtaacagatg attttcctaa
     1021 ctcgacgccg actgctgctg caattttctc tgctaatggg cgattggaat ttaacgcaaa
     1081 aatttttaat cttgggtcaa agtaatgttt tgacatgggg acctccactt tctttttcac
     1141 aactctagaa ttctacctaa taaatagtag tcatattttt taaataaatc aagtgatttt
     1201 gcaaaagtct tagtttagat aagggagttt ttttgcatat ccttctttat tgacttgtct
     1261 tgctctcgca attgccagcg catattctgg aatattgtct gtaattgttg acccggcagc
     1321 aatcgaactg tttttagcta cctcgacagg tccgatgata ttcgtgctag aaccaataaa
     1381 gctgtggtcg ccgacagtcg tatgatgttt gttctttcca tcatagttga cgaagacaac
     1441 accacatccg acattgattt cttctcccag cgtagcatca ccaacataag tcaagtgacc
     1501 gactttagtt cctttgccga tttgagcatt tttcacttcc acaaagtttc cgatatggac
     1561 gttttcgcca atttcagctt ttggtcgtaa atgtgcataa ggtcccacat ctgcatgttt
     1621 cttgacatgg ctgctttcaa tgactgagtt ttcaatgacg acgtgatcct caatcctact
     1681 gtctacgatt tttgaatgtg acccgatgac acaatcagaa ccaatgactg tatttccttg
     1741 gatttgtaca cctgcttcga tcaatgtgtc tggaccgatt tctacgcctg catcgatgta
     1801 tgtcgttgct gaatcgacaa agcttacgcc attgaccata tgcatctggt taattcgctt
     1861 tctcatgatc tcatttgctt tagctaacgc gatccgatca ttgactccca ttgattcttc
     1921 aaaatcatcc gtttgataag cagcaactgt atggccttct tcttttaaga tttcgatgat
     1981 atctgttaga tagtattcac cttgagcatt gtttgttcca actttgctta acgcatcgaa
     2041 caaagcttcg ttgtcaaaac agtaagttcc tgtattgatt tcttgtacaa gagcttcttc
     2101 tggtgttgca tctttttgtt ccacgatttt ttctacgatc ccaatatggt cacggatgat
     2161 tcgtccatat cctgttgggt tttctgcttg tgccgtcaag atcgttgcac ttgcattttt
     2221 tccttggtga tattcaaaaa gattgttcag cgtttcagta gtcaataatg gtgtatcgcc
     2281 actgataact aacgttgttc ctttttttcc ttccaagaaa gaagcagctt gcaaaacagc
     2341 atgtcctgtt cccaattgtt ctgcttgtaa cgcatattta ctgcgttctc ctagttgtgc
     2401 tttaacttgt tctgctccgt gtccaacgat cgtaatcact tcatctggtt tcgtttcact
     2461 gacccgatta atgatatgtt ctaccatagg tttaccagaa acgggatgta aaactttata
     2521 taattttgac ttcatgcggg tacctttccc tgccgccaaa ataattgcat aacgtgcgtc
     2581 caactgcgtc actcctaaat atagtttgct gatttcagtt tatcccagta tacccatttt
     2641 ttcaacaaaa caagtgattt tcttttatcc cagcgttttc tggataaaaa aatagataga
     2701 ccataacggg cctatctatt tggtaaccgg tgctctcctg ccaactcctc ggtcacaagt
     2761 cacactactc ataaaacatg aaaagctgtt ttttgaaatc gtttcttgtg acttagagtt
     2821 aaacggtagg cttacaacct cttcattaaa cgtttttcaa tcagctgacc ttcggtatta
     2881 gctcaataaa cggcaaaata tgaggagcaa tttttccgtt tattgagcta atactcagga
     2941 caggacgctg atttcacaac ctctagataa acggtgttca aaagccagtt tctcggtatt
     3001 aagccaaatt tatgaaaaaa tgtggaaagc cattttcaca aaatttttct tactactcga
     3061 aactaagcgg ctttttcaca acctcttatt ctgaaaaata atttcctggc acaaccgtaa
     3121 tatttttcgt ttgagtatct acatctttga cataaagcag tgacgtataa tcatcgatgg
     3181 cgcgatgacc gttgaatttt gattcggcaa atacagtgat gccaacaagt tctgattcga
     3241 attcttcaat caagctcttc attccgttga ctgttccgcc gcctttcatg aaatcatcca
     3301 ctacaaggac acgtgaacca cgtttcaaac ttctcttaga cagttccatc ttttcaattc
     3361 tttcagaaga tccagacaca tagttgacac ttactgttga tccttctgtt atttttgagt
     3421 cccggcgtac aataacgaat ggcgcattca gataatagga cacagcttgg gcaataggta
     3481 cgccttttgt ggctacagtc attacagcat cgattttttc accaaggtat ttagaagcaa
     3541 tgattcttcc aacttgacgc agcagttcag gttctcctaa caaatcagag agataaacat
     3601 atcctcctgg aagcagacgg tcttgttctg atagacgttc tgctagagat tcaatatatt
     3661 ttttcgcctc ttcatatgaa atttcaggga tgaacaatac accacctgca gcacccggga
     3721 ttgtttccaa ggttccatac cctcgttctt taaatgtttt cttgatgatt cccaaatctt
     3781 cactgataga agatttagca gattcataac gttcggcaaa gcttgttaag gaaatcaatt
     3841 catgcgggtg attcaataaa tactgtgtca tgtcaactag acgttcactg cgacgtactt
     3901 tcacctattc caactccttt taagaaattt tatcgtttta cattatataa gtttttcttc
     3961 aaaaattcga gcattttatg aaaaaataag aaaatagttc ggtatttatt aaaataaaaa
     4021 gaagcctata aaaaattttt cgtttttata aggcttcttt tctttataat ttagttattt
     4081 tttcttctga aggcaaccaa tattcgtttg atgatattta caatcaggaa caaagcaata
     4141 aagactaatg tgattgttgc tcctggaggt gtatctagat aaaacgagct agttagtcct
     4201 gacagcatcc ctagaaatcc tacacaaaca ctgatagcaa tcacgacatt gaagcttttg
     4261 cctaatcgca taccgattgc tgcgggaaga accatgattg cggatatcaa aagtgcaccg
     4321 gcaatcggga tcatcacagc aatagccaca ccagtaatca cattgaacat catcgacatc
     4381 aaatgaacgg gtagcccatc cacgtgggcg gtatcttcat caaaagtcag aacatacatc
     4441 ggccgtttga ataaaaagaa caatataccg atggcaacga ataagattcc taaaaagatg
     4501 acttgctccc atgtaatggt cacgatcgaa ccaaacagat aggattggat acttgttgct
     4561 gaattccctc cgctcaaatt catcaatact aacgctagcg ccaaaccacc agccattaaa
     4621 atggcaatgg agatttctga ataggttcgg tagatcgttc gcagatactc caatatcaca
     4681 gctgctaata caacgactag catggtcgta agtgtaggat taaggttcaa aaagaatcct
     4741 aacgctaccc ctgctaaaga gacatgagaa agcgtatcag ccatcagcga ttgtcttctg
     4801 atcactaaaa acacacctag catcggggcg attccggcaa tgaagatagc ggcaagaaac
     4861 gctcttctca tgaattcata tgaaagcaac gccattgaga atcctccttt ctcaccagtc
     4921 ggatctgtct gtccgcatac tgtttgatat cttcatgatc atgggtgatc attagaactg
     4981 atttcccatg gacatgcgca ctatgtcgga gaagacgata aaattcattt ctggattctt
     5041 catccatacc tgttgttggt tcatcaagaa caaataagtc agggtcagta gcaaaaatac
     5101 gcgctaaact gattcgctgc ttttgtccgc cagacaattc acctattcgc cgatttcgca
     5161 tatcccacat ccctacagct tctaaagcac gctgtacatg ttgatgatct ttttcagaga
     5221 gacgcttgaa ccagcggcct cttggatatc ttcctgaacg gactaattcg atcaccgtac
     5281 taggaaaacc tgcattgaaa gatgcaactt gttgaggaat ataaccgata cttaattttt
     5341 ttccttcttg atttttctca gcaatcttta tcattccttt tgaaggtttc agtaatccta
     5401 acgatgcttt caccaaggtt gacttggctg ctccattttc tccagttaaa atgacaaatt
     5461 cacccgcatc tacatgataa gagacatctt ctagtacagg ttcatcatca tagtaaaagg
     5521 tcaaatcaga tatttcgata taacgcacct tacaacctcc attctaaaac ttaattgata
     5581 ctttctttta aagctttcag atttttttcc atgacagaaa tataattttc gcctgctttg
     5641 atttgttcat tagtcaagct ttctaaagga ttcaacactt ctagcttcac tcctgtttca
     5701 ttcgacaatg tctcagctac cttcgaagag gcattttctt caaaataaat cactttgatg
     5761 ttgtttttct tcacaaattc ttttagctca gctaagcgac ttggtgtggg ttcctgatct
     5821 ggtgaaacgc ccgaaatcgc tacttgtttt aagtcgtatt gattcgctaa ataagcaaaa
     5881 gcagcatgct gagtgacaaa tgtgcggttt gttgcatctt ttagctcatc ggagtatttt
     5941 tgatccagtg cttcaagctt tttgatataa gcatcggcat tcttcgtaaa agtttccttt
     6001 ttatctggat atttttcgcc taattcttca gcaatcgttc tgacttcttt tatagctaat
     6061 accggatcga gccaaacatg tggatcgtat tcatgtgaat gaccatgccc ttcttctgat
     6121 tcttcatgtt cgtctgcttc ttgcgattct aaacggtcga ttcctttagc tgcttcgatc
     6181 atcaaggtct gtttgctatc cactgaatcc tttaacgaat ccacaaaaaa ttccatgtct
     6241 gaactattat acacgaaaac atctgcatcg gaaatttctg ctctttcttt tgcacttggt
     6301 tcgaaatcat gcggctccgt tccagcaggg atcaaaagtt tcacgtttcc ttcatcccct
     6361 acgatctctt ttgtaaaatc atacatcgga taaaaagtcg taacgatcgt caaatcctct
     6421 tttttgtctg cttccttgtt cgtatttcca catgctgcaa acagtaaagc acctatcatt
     6481 accgtagctg tcaaaagata ttttttcatt tatatgctcc tttcaatgaa caaatcggaa
     6541 ttttacgatt tattaacgtg aactaatgta tcaaaataaa aaaacacagt caatagaaat
     6601 ccatcaattt ctgatttaag catgtatatt cttgattaaa tcgtaaaatg gatgagttgc
     6661 tgctcatatc tagccatttc actacaataa aaaactgaag aataccattt taggattcct
     6721 cagtttttca tcacctattt tacttcttat attttattgc agggttcgta ctaaataaac
     6781 ttcctcacaa aaacctttta acccattata tactctctgc gctcttgaat aatgttgaca
     6841 caaggcaaaa acggttggtc cgcttccact catcaatgca gcatctgctc cgtacttgat
     6901 catacgctct ttgatttgat ggatgactgg atgccgcttt cccgttatat cttctaaact
     6961 gtttcccatt tttttgatca tctgctgata atcttgctct cggatggctt cagcaagtcc
     7021 gtggatgtct tgatgttgga tggcttgcgt atctacttct ctaaacactg tacgtgtaga
     7081 gacactcatt cttggtttga ccaacacaac ccagcactgt ggcatagaag gtaatacttg
     7141 gatttcttcc cctttgccac cgacaaatgc cgtacttccg tagacacagt aaggaacatc
     7201 tgtaccgact tccaaaccga tttctgccag ttcttctaac gaacagccca gattccataa
     7261 ttggttgatc cctcttagag cagctgcaca gtctgtactt cctccgccta atccagctgc
     7321 tactggaata ttcttcttaa caaagatctt gacaccggtt ttgatattgt atttattttt
     7381 tagcaataaa gcagcttgat aaacattgtt ccgttcatct accggtaaaa atgctttatt
     7441 tgtttctaca atgattttgt cttctgttat ttcttcaaaa aatagatgat ctgccaagtc
     7501 tacgctcgac atcaccattt ccaactcatg atacccatct tgccgtctat ataatacatc
     7561 cagtcctaaa tttatcttgg ctggcgcttt ttcaatcaat tccatcctct cacccattcg
     7621 aaaagtctaa gtcgcaagta ttctatcata gggaaaaata aaagtatagc ttatgtctgc
     7681 ctagtggttg attttgtcat cgtttcaaca gctttcacag aattttctct tcataatcca
     7741 aacaagttct agtgattctt ataattctgt gagcacttct tctgccaaac tcggaacatt
     7801 tcctttttct tttcctatca gactgagtag ctgcatggta gcaaatccga aattacttcc
     7861 tttcctataa gcaaaataac gtccttccca atgatcgaca tattttaatt tcttttcata
     7921 agcagactgg aaggaataga aaaaattacc ataattatat acgatatgca tgactttttc
     7981 ttgaaagaaa gaaaaatctg tttctccaac attagctaat ggagctaagc ctagattggc
     8041 ttccgagtag cccattttct cgtatacaat aaacagattg gctaacagat agtcagctaa
     8101 ttcctcagat tctttaggta agacccgcaa caaatcatat cccgcctgct tcttcgtcat
     8161 cggctgagcg gtgatgaagc caacgacttt ttgatcttta cggacaatac cgacaccgct
     8221 agataataca tatgatttat caaatcgtcc cacagagaag tatttttctc gtgcaccttg
     8281 aagccatttt tgtgaaactt catttacagc ttgatgtaat tcttccggca gttgatcgta
     8341 ccaagtaaaa tggtatcctt ctttcatcaa acgttgatat tcaagttgct gactcagccg
     8401 agacaagtct tctgttgcta gatcaacaat ccctgcttca cctactttcg tgaagtgaaa
     8461 acccaattca tgaagcatca ctacgtagct ttctgatatc ttataaaacg caagctgata
     8521 gcctaaacaa tctgcttgtt tcataaactg attcgttgct gcccgcatca ttttaggatt
     8581 gccaactgga tctcctaaaa caaagcattt gtttcctttg atctgataac caaaaacgac
     8641 ttgatcttgg tcgtcttctt ggtaataaaa ataactgtaa cctgacaagc gaagctgatg
     8701 gcttgtagct gtgcctccgt atgtttccaa taaacggtca aaacggtctt tttcgtactc
     8761 actgccaagc ttcgtagtat cttcagctaa atattgataa agcgccacta aagctagcaa
     8821 tgagatgccc aaaccaataa gccctgagaa ccacacatca tctgaaggaa acaaaataaa
     8881 atgatttcct gttattcgac cgactaaaaa gcgtccgctg tgatagcctg caattgcgta
     8941 aacgataaac aaaaagccga acaagctagc atcaaagatt atagctcccc aagaataaac
     9001 gaattttgtt cgataaaatt cttttctgga taaccacaca gctaacagaa tcaagacata
     9061 taccaatatc aactgccaag ataacgtacg tgtgattgta tttaaaatac caaaagatag
     9121 taaagcaatc gtaggcagaa atgccttttt gacttttact gaaagtgctc tagcaaggcc
     9181 gagtaataaa aagccaacca atagattcac tgtctgatct aaaaaattga atgagaacgg
     9241 caataatact tgaaatagcc gactgattgc agacagatta gtgattgttg atagaagtac
     9301 catcatgatc cccgcaaaat agacagcact tacgagcacg atatgcgcaa ccttttggaa
     9361 aaacagtcgc ggaatgttat ctaaaaatcg attgattttg actcctgtat gtgtgatgaa
     9421 caatagaagt cccgtcataa aaggtagaac ataataaaac aaccgataat ataatagcca
     9481 aactactgct acatcttgcc gaacagacaa ttgactcatt cctaagatca tcaaaacgtc
     9541 aaaagtcccc attccacctg ggaccatcgt cagcattcct atcaatgtag caatcatgaa
     9601 cataggatag atcgaaagca tcgaaatatc tattctcatc aacttgccga tgatcaaaaa
     9661 taccgcaagg gctcccgtcc attgtccaaa ggatgccagt agcagaccaa gcaagccttt
     9721 tggataaaac tcgaagaaca atgtctttct ctttagataa gcaaaaaaga aaatgactgg
     9781 tgctaaaaaa ctaccgccga aaagccagat ccaatagctt cgaaaaatac tttctgactg
     9841 aataaaaaag acatcaataa atgtaagaaa cgaccataca gacaaaccag tcagcataaa
     9901 tagtgcgact tttgatacag tggctaaaac catttttcta tttgtctgct ttccataaaa
     9961 actagcccgc agacttgctc ctaccacacc accaaaaccg gcgagattgt tgatcgtgtt
    10021 tgttacccac gcagcaagaa gaaactcttt tctttccatt tttggttttc cttgtttttc
    10081 taagactctg atcgtcaccc aatcatacaa caacatcgga gtgacaccca gcagtccagc
    10141 cagaatcatg agcaggatcg tcatgcggct ttgttgtccc atcctttgcc aaatatcttg
    10201 ccaactcatg ccattagcaa tatttgcgac ttgatttgcc acaaagacta acacggagcc
    10261 gaaaaaaatc agttttaaaa tcagactatg ttcctttatc cattgcagca tcaagtatcg
    10321 tttatttttc acattttccc attcctaact tgtatacttt tgtgtcatac cccaatgtta
    10381 tcttatttat tttaattttt ccactttaga cctgttcttt gcttgcgatg atagaaaaag
    10441 aaagatatcc taatgctaaa ggagaggata acatgaaagt aggatttatc ggcacaggga
    10501 atatggcaca agctattatt gatggtttat taaaaaaagg aacagtctcg aaagaagagg
    10561 tgttcgtttc cagtggacat tttgaaaatg cacaaaaatt tgctgctgaa actggcgtcc
    10621 atgcatgcaa aagtaatcag gaagttgcat cacaatcaga tatcgttctt ttagccgtga
    10681 aaccaaaaat cattgaaaaa gtattggaag aactaagaga atatagccag aaagtcttat
    10741 tcatttctat tgcttcagga aaatcattaa tagatttaga aacagcgctt gaagatcctc
    10801 aggcctccat cgtacgtgtg atgccgaatg tcaatgtcag cgtaggagca ggcgtttctg
    10861 cgatttgcaa aaatgaagct gccacggagg aacagcttca gcaagctacg atgatttttg
    10921 aagcaatcgg cagcgtctat cctttagcag aatcagattt cagtacattc attggccttg
    10981 ctggcagctc acccgcattc gtttacatgc tgatcgatgc gatgggacgg actggtgtac
    11041 tgaatggttt gtccaaacag acagccactg agattgctgc aaaagcaatt atgggttctt
    11101 gtcaaaaatt cctttcaagt gataaaaatc catgggaact tgtagaccaa gtttcttctc
    11161 ctggcggtac aactgttgca ggtgtagttg ccttagaaga agcaggattc atcccagcaa
    11221 tcatcaaagg aatcaatacg acgatcgaga aagatcttga gatgttgaat aaaaaataat
    11281 gatagcaatg ttttttcgtg ccttacaaaa aaagaagagc tgtggctttt gccgcggctc
    11341 ttcttttgta ttttttatta tttagcataa tcagttgcac gagtttcccg aataacgatt
    11401 actttgatgt gtccaggata atccagttct tcttcgattc gtttacgaat atcacgtact
    11461 aaacgaacag cgtctaaatc cgagatttct tctggcttga ccattacccg aacttcgcgt
    11521 ccagcttgaa ctgcgtaact tgattctaca ccggcgaagc tgttcgaaat attttccaga
    11581 cttcttaaac gacggatgta gttttctaat gattcacttc gcgcaccagg tcttgctgct
    11641 gagagcgcat ctgctgcagc tacaaggaca gagataacag aagtagcttc cacatctcca
    11701 tgatgagaag cgatcgcgtt gattactact gggttttctt tgtacttggc agctaattcc
    11761 gcaccgatct caacgtgaga tccttcaatc tcatggtcaa gtgctttccc aatatcatgg
    11821 agcaacccgg cacgttttgc taattggata tcttcgccaa gctctgctgc taagatacca
    11881 gctaattttg caacctcgac cgaatgcttc aagacgtttt gtccataact agttctgaat
    11941 cgcagacgtc cgatgatctt gattagatct ggatgaagtg tatgagcacc gacttcaaac
    12001 gctgcctctt ccccgtattc gcgaatacgt tcatccattt ctttacgaga tttctcgacc
    12061 atttcttcga tacgcgctgg atggattcgt ccatcttgta tcagtttttc caaggtcatc
    12121 cgtgcgattt ctcttcggat tggatcgaat ccggaaagaa caactgcttc cggtgtatca
    12181 tcgatgatta aatcgatacc agtcagcgtc tcaagcgttc gaatattacg accttctcgt
    12241 ccaatgatac gacctttcat ttcatcattc ggaagggtaa cgactgaaac agtcgtttct
    12301 gaaacttgat ctgctgcgca gcgttgaatc gctaatgata ataagttttt cgctttgcga
    12361 tctgcttctt ctttggcacg ctgttcagat tcttttacca ttagagttaa ctcatgattc
    12421 agctcttctt cagtcgattt catgatgaca tctcgtgcgt cctcttttga taaaccagca
    12481 attttttcta gttctttttg ttgatcttca atcatttttt caacgtcttt ttctcgctct
    12541 tcaattaatt gctgttttga actaagtgct tcttctttac tttcaagtga gttctcgcgt
    12601 ttttctaacg agtcatcttt acgattcagc gtttgttcgc gttgaatcaa acgattctct
    12661 tgagatttta attctaactt actttctctc agctcacttt caacttcaga acggtatttc
    12721 tgattttctt ccttagcttc taacaatgct tcttttttta gagtttctgc ttcttttttt
    12781 gcactatcga tgattccagc agctgatgat tgtgcaccag ctatttcttt ctcgtgacgt
    12841 gactttgcga ccataaaccc taaaccaaga ccgacaatta aaccgatgat agcgaggaga
    12901 atgttgaata ccataaaatc cacctccata ctatcttttt catttttatc atctatacag
    12961 cttctatgat aaattattct aaactcgtca atatgcatct tcgcatatat gtgtacaaaa
    13021 aacatgcaca actttattct aatgtttgta ccccgtagtg tcaactttaa ataaacaaag
    13081 aaacggcttt ctacttattc attaaacgat ggtttttaaa ataaatgaca ctagtttcat
    13141 ataggtaaac ctttaaattg agaaactttt ctattaaatt attctttgta gatgaacaga
    13201 tatttttatt ttatgtaccc actcgtataa ttaaataact cacgatttct ttattcaata
    13261 aaaaaacggc aggtcaagga gagtacctac tcttcagacc agccgttttt gtttatcata
    13321 atttttattc ttctactaaa ggcaattctt cttgtccttt ttcatcttct gggacagcga
    13381 cttcttcacc aataccataa gctgctctaa ctagagcaga aacttctgcc atcatttcag
    13441 gatgattagc catatagatt ttagcgtttt cccgtccttg accaatccga tcttctttat
    13501 aagaatacca agcaccgctt ttatcaacaa tgtctttttc tactgccatg tctagaagtt
    13561 ctccttcttg tgagatccct aaaccataca tgacatctac ttcagcgatt ttgaaaggag
    13621 gtgctacttt gttttttacg actttgatct ttgtacggtt accaacaata tctgtacctt
    13681 gtttcaattg ttctgcacga cgtacttcca aacggatcgt tgcgtagaat ttcaatgcgc
    13741 gtcctccagg agtgatttct ggattcccaa acatcacgcc tactttttca cggatttggt
    13801 tgatgaaaat agcgattgtt tttgttttgt tgatcgaacc agagagttta cgcaatgctt
    13861 gagacatcaa acgtgcttgt aacccgacat gtgagtcacc catttcgccg tcgatttctg
    13921 ctcgtggaac taaagcagca actgaatcga ctactacgat atctacagcc ccacttgata
    13981 ctaaagcatc agcgatctct agaccttgtt ctcctgtgtc aggctgtgaa agaagtagtt
    14041 catcgatatt cacacctaat ttttgtgcat attgcggatc taacgcatgc tcagcatcaa
    14101 tgaaagcggc cgttccgcca tttttttgta cttctgcaat agcgtgtagt gcaactgttg
    14161 ttttacctga actttcaggt ccatatactt cgatgatacg tccacggggg taaccgccga
    14221 cacctaaagc gacatctaac gcaagagagc cacttggaat tgtagagatt tgttggtcga
    14281 ttttttcgcc caatttcata atagagcctt taccatagct cttttcaatt tttttcagtg
    14341 cagcatctaa ggctgcttta cgatcatctg ccaatacgat aatcctcctt atatttacaa
    14401 atcagagcaa catttcatta tccttatcat atctttttta gtgaaaaaaa gcaagaaaaa
    14461 accgaacaaa tattcgcatt tatcattttc ttaaaagctg ttttctcaaa agatcaaatc
    14521 cttgcataac cgcattatat ctgatagcag cacgatctct ggcaaagtga tatttttccg
    14581 aaaccacgcc gtctttagat gaaatagcga tccatactgt tcctgcagat tgaccttcta
    14641 acgtgtccgg tccagccact ccggtgaaag ctacactgta atctgttctt gctatctcac
    14701 gtgcttgaat ggccatctgc tccacacatt ctttgctgac tgttccatat tctgctaata
    14761 gctccggatc aatctccaga aaaccagctt ttgtttggag cgagtaggta acgaatccgc
    14821 ctggaaatac ttcagataca ccagcaatgt cgcctaatgc ggcttggaag gcgccggctg
    14881 tcaaactttc cgctgctgtt acagtctgct tgttttcttt cagtagttcc actacgactt
    14941 ttgctagcga attatcatcg ccgtatccat aaaaatattc ccctactcgt tcttggattt
    15001 tttcttctaa tgctaaaaga gcttgattcc ctgcctgaac atcatttgtt ttcactgtca
    15061 gtcgtaatgt cacttcattt ggtttggcat atggtgcgat cgttggattg atctgtgtct
    15121 caatcagatc ttttagctca gtgaccagtc gcgattcacc aatcccataa aagcgcaaaa
    15181 ctttagaaat tagtttttct tcagaaggaa aacgttcctc tagtaaagga cgtacttgtt
    15241 ccacaaacat tggtttcaac tcattaggcg gaccgggaag aaggatatac gcatgtgtat
    15301 ctgtttgata aaaagtccct aaagcaagcc ctgtacgatt tggtagagga accccgcctt
    15361 cgataatctg ggactgttgc agattgtttt tggtcatttt tcgatgggtt gtttcaaaat
    15421 atgccaataa ttttttgtat ccttccgtat tttgtatgag agacttaccg aggtgagccg
    15481 cagttgcttc ttttgtcagg tcatcttctg tcggtcctaa tccgccacat aagagtatga
    15541 gttcacttct tgtttcagct agagcaatca actcttctaa acgctgctga ttatctccta
    15601 caactgtttg ataataaact tcgataccta gatcagctag ctgttctgac aagaaagtgg
    15661 cattcgtatt cacgacttgt cctagtaaaa gttctgttcc gacagctatt atttctgctt
    15721 tcattacttc ccgctccctt atatagtata cgctgtattt ttatattttt ttatttaaaa
    15781 agagggcaag gagctgtgac aaaaatcttg tcacagctcc ttgttccaaa taaacagtgt
    15841 tctcctgcca aaacctcggt cataagtcac aatatacata aaacatgaaa agctgttttt
    15901 tgaaattatc ccttgtgact cagagttaga cggcaggctc acaacctctc cactaaacga
    15961 tacttacatt gatcctttga acacaccgct gtttttgatg aagtaatcca cacctgaata
    16021 gatagtaaag atcagacaag cataaagcat gatttgatct actggaatac cgatcaggct
    16081 gaatgggata ttattgataa acagcaagat aatagcaacc atttgtgtag ccgtcttgac
    16141 ttttcccggc caagctgcag ccatgacttc tccatgttcg acaagtagta aacgcaagcc
    16201 tgtgacggct aattcacgac agacaatgat cgctactacc caaccagggg cctttccttg
    16261 gtcaaccaac atgataaaag cagtcataac tagcatttta tctgccaacg ggtccgcaaa
    16321 cttgccaaaa ttagtgacaa ggcctcgcgc acgggcaatt tttccatcta accagtctgt
    16381 gatactagct aaagcaaaaa taactgcacc tactagctgt gtgacagcca gtgtggtgtc
    16441 tcctacgtta aattgtcccc aatctaaagg taaacctaca accaaaatga aaatcgggat
    16501 catacaaatt ctaagtacag ttaatttatt tggtaaattc acactatcga ctcctttctt
    16561 ccctattcta cgtgactatc agcgaagttt ccaccgatat tatttacttt tccaaatgaa
    16621 tttattcaaa ggagtatttt tattgaaatt gatctttttg aattaacgaa gaaggaccgc
    16681 gacacagatt tgtcacgatc cttctttttt atacctacaa gtaaacagat gcgtaaacta
    16741 atttatacga tcattctgcg tattgaagag taaggttcac attttttgga ctctgattgt
    16801 tttcccctgg attaactggt acggattctc cattcgcttt gatcgttgca ttgcttgctg
    16861 caccaatcgt gatggtcgca tttgttgctg tttccggtaa cacggtactc tgtgtttcat
    16921 ttgctgccag tgtcccttga taaacatagg cattgtctac tagcacacct aaccatacac
    16981 gattgacagc agtaaattca agggttacag gcttggtagc gtctgtgata tttactgcga
    17041 tggcactgcc agaatcttct cctgtagcta ttgccatttt cttttcttca cttgattttg
    17101 ttgttgattc tactgtagaa gactctttgg tctgcgtgct ttgctctgag gaagaggact
    17161 cctcgactga tccttctact ttaagcgaag aagctgtgtc tccgattatt ggatcagctt
    17221 gacgatcttg ccaagtcata tagcccacga caacgacaat cgccaaagca accaatccta
    17281 ataaaatgac aggaagactt gtccaaaagc gacttggatg cgattcttcc tgatgcattg
    17341 cttttctaga agtacttact gtttcaggct gcggacgttc agggaccgat cctgtcaatt
    17401 tgcttttccc atcaaaaaca tcgactaaat ggtctccatc ttctcctaca gcttcagcgt
    17461 attgccgaat aaatgcccgc acgtaaaatt taccaggcaa ttggtcaaaa tcatcattgt
    17521 cgattgcttc caaataacgt ttttgaattt ttgtaatctg ctgtaattca tctaaagata
    17581 tttttttatt caggcgtgct tgccgtaatt tttctccgat ggtttcaaaa gccactcgtt
    17641 catcttctcc agtctgtttg attctccgaa gcatctgctg ttgcaacgaa agacgttatg
    17701 tttgggtgct gtgacaaaag tcatgtcaca gctccttttt tccgaataaa cattgttctc
    17761 ctgccaactc ctcggtcaca agtcacaata tccaataaat ataagaagct gttttttgaa
    17821 cttgttcctt gtgactcgga gttaaacggc aggctcacga cctctttctt aaacggtgtt
    17881 caatcagctg ttcctcggta ttagctcaaa aaccggcaaa atataaggag atatttttcc
    17941 gtatgtttct ctaatactca ggtcaaaacg ctgatttcac aacctcttcc ttaaacggtg
    18001 ttcaaaagct tgcatctgcg gtaataagtc caaccaagtt aaaaacatta agaagctgtt
    18061 tttacttggc tgttcttatt acttgatgca gggcagcttt ttcacaacct cttggtacac
    18121 ggtgttccag aagtagcttc ttcggcaata agccgaaata tcacaaaaat ttgagaagca
    18181 attttcgtaa attccttctt atttcttgaa gctgaccact tctgtcacaa cctctttgat
    18241 tacttcgttt gattttattt taatataagt tgattaaaag agagcatgat ttgttttatt
    18301 ttctcactaa tttttccaac acaactaaga ataccataaa agctgatttt ggaggaggtt
    18361 cctactacaa gtctaaaacg aaatttaaga cttttcctca taaaatactg gtttattttg
    18421 gtctcatgta aaactcgctg aaggcctctt cacttataaa tgcttcccca gctgccagta
    18481 cgtctttcat ttggatcgaa tcgatgattt caggaagatc aaataaagtt cgatcgccaa
    18541 ataaactttg cgtaaattga ttggcaatat attcgatcga atttaatgat tggaaatatt
    18601 gtccaagcat tttcttcttc agcaaatcga gatttgtttc tgacacttcc ggatcatcag
    18661 cgaatccaag aatgatttct ttgacttttt ctgctgcttt ctctggttcg tccgtatctc
    18721 cgctgaagtc cgcaaagtga aattcacgat ccaagctgaa ttcaaaacca aagctgtcat
    18781 cgataattcc ttgattgtac atcgctagat agtttcgaga agtattgcct aaaatcattt
    18841 ggaacaacag attgattgct gttttatagc gtaacagttc tgttccttct tgcggcaatg
    18901 tgtctaatcc tttaatacca agtacaaatt tatctcgtgt aatggctgct tccaatgcac
    18961 tttgtttgat gatttctttt gtgttttcag ggaaataacg tacaatttct tgctttggag
    19021 ggaaattttt tgcttcttgg ttttcccgaa taagtttcat caatttctca ggctccatct
    19081 taccaactac aaataaaacc atattgcttg gctgataaaa cgtccgatag cacgtataca
    19141 agtcttgagc tgtgattttg tcgatacttt caaccgtgcc cgcaatatcg atatgcaatg
    19201 ggtgtgtagg atacaagtta tttagtatgc caaaaaacat ccgccagtta gggtcgtctt
    19261 catacatttg gatttcctga ccgatgattc ctttttcctt gtttacagtt tcttctgtga
    19321 agtaaggtgc ttgtacaaaa tcgatcagag tcgtcagatt cttttctacc tgatccgtcg
    19381 tagaaaacag atagctggtt ttcgtaaaac ttgtgaaagc attggcggaa gctccttgtt
    19441 tcccaaataa ttgaaagaca tcaccatctt ctttttcaaa caacttatgt tctaaaaaat
    19501 gggcaattcc atctggaact ttcacctttt ctttttcacc atagggaata aattcgttat
    19561 cgatcgaacc ataattcgta ctgaacaaac catatgtctt gtgatagtca tttttaggca
    19621 acaaatacac ggtcaaaccg tttggcagta cttcatgata aagtgtttca ttgatttgct
    19681 catattctgt tttattcatt tgcatttcct cctgctaaaa agaagattgc ctgcaattcg
    19741 atttgctcag ctacttgttg tatctctttg atcgttacgc tctccatacg tttcaaccat
    19801 tcttcatcag ataattttgt ttccggcagc cagctgtcca aaaaagaagc ttcgattgcc
    19861 gcttgcggag agtctagaga aagcagatat tggtttctca gcattgcttt tgtctgagac
    19921 agttccaact ctgttatttc accatttcgc aaactttcta attgctcgtg aatcagatga
    19981 agtacttgat ttcggttctt ttcatcgata ccggtttgga cactcatgaa tcctcggaac
    20041 gtatccacgc tactagaggc ataataagct agactttctt tctctctgac attcatgaaa
    20101 agtttagagt gaggaaaacc gccaaataaa ccgttaaaga ccattagcgc aaaacgttct
    20161 ggttcatcgt aatacacatt tgtctgataa gctaggttca gctttgcttg aacgattggc
    20221 tcacgtactt gtcgttcctt cacgatattc acttgaggtt gggtataaaa cagatctgga
    20281 taaactgttt cccgcgactc aaatggtaat tgcccaactg cttcagctgc tttgtccgga
    20341 tcaacatcgc cgacaacaaa aatgtcgatt tgatcatttg ccatcatttc ttgatagtag
    20401 gacgctagcg aactagcagt gatcttgtcc aaatcttcga ctacgcccaa ccctgggatc
    20461 ttttgttccg ggctgttttc aaaataaagt tcttgcaagg cataggaagc aaaagtttgt
    20521 ttatcttcct tcaaactttc caaatataga cgcagattgt tcttttccaa gtcaaacgtc
    20581 aactgatcaa actgatgatt tttaatattt ggataaaata aaacctcttt taaaaaatct
    20641 accgcttgag aaaaaaggtt tggatcattg acatattcac cattcacaaa actgatccct
    20701 gcgtttagcc aatgtaaatt tccttttttt ctaactgata atccaaagct tgcgccataa
    20761 agctctgcaa gttgcgcact taactttgtc tgatccgaat aattcaaact atttgtttcc
    20821 aacatgctgc tgagaagtga acgtttcgtg atgacttctt gttgcagacg cgcagtaaaa
    20881 cggataaaaa tccggatcgt tttgtattgt tttgttggta agacatgaag attcacgcct
    20941 tctgccaatt gatacaccat atttatatgc tccttttcac agttgattgc ccgcttactc
    21001 ttttaatggg tcaacctgcc ttttttactt attcctctgc ttgaaattta taagttcagg
    21061 caattcgccg ttttttctaa atgatgttac actttatagt atagcataga tgttttttat
    21121 caaaagaaac agacggctaa aagcgtatat tgttttttta ttttttattt ttcgatatac
    21181 taaagacaaa taaaagaagg gagggtcatt catgatcaaa gaattcaaag agttcatcat
    21241 gcgtggagat gtcttggatc ttgctgtcgg cgttgttatt ggtagtgcgt ttacaagcat
    21301 cgtaaaccaa gtggtgcaag gcttgatcac accactaata ggttggtttg tcgcaatgat
    21361 cacaggtact tctgatttag aaggagcact ttcaattctt gactggtcgc cgacaaaagg
    21421 cgtcacattt gcgtttggta acgttattag tgctatcatt acatttctga tcactggttt
    21481 tgtcttattc ttagttgtca aagcggcaaa ccgtgcgaag aatttacgct ccaaagaaga
    21541 gcaagtggaa gtggaagaaa ctcctactgc agaagattat cttagtgaca tacgcgatct
    21601 tcttgccaaa caagtggcag aagacaatac acatccagta gagcaaacaa atctttccga
    21661 tacttctaaa taataaagaa tctaaaaaaa agaaagccga ttttcagtgt cggctttctt
    21721 tttttagatt cttaacttgc tacttgttcc tttttcatgt cgatatgtgg aatatcatct
    21781 tccaaataca catctgagat tgccttgaat ccaaacgact cataaaaagc ttgtaggtat
    21841 tcttgtgcgc cgatcacgat tggtttttct ggaaaatttt tctggatcat gttaatcgtt
    21901 tcttgaacaa tctttcttcc taaaccatct ttacggttgt cctgatgaac aaggacacgt
    21961 ccaaaatgga tactctccgc ttcttcatat actcgcgtgt aggcaaggat cttcccatca
    22021 gtatcttgaa aaaacgtatg ccaagcttct ccatcaatgt catcaacttc ttgataagga
    22081 cactgttgtt ccacaacaaa aactgcgatt cgttctttga cgatcgcgta aaactctgct
    22141 gttgacaatt cttcaaattt ctttacctga tattccacta agcaaacgcc ccctgctttt
    22201 ttattcttag cataccgatt cgcacacaaa aaagcaaacg aaccttacga atctcaggct
    22261 cgtttgcttt ttaaactgct tcagttaaaa attcgatctc aactgtccga gtaagtacat
    22321 ctgaatagct gtaagatact cgttcaaaag aattttcttc aggatccaaa tcaacaacga
    22381 atactgaagg ataggtttct gttaaaacgc cgcggcgttc tgtttgacgc tttcttcctg
    22441 tctgagcaac caacatgatt gggctgccga tacgaccttc taaatctttc ttgattgaag
    22501 ctaaagttgt tggcatacag ttcacctcta ctatcaacta taccacatat ttttaaaatt
    22561 ttcaagttta ccataaaaaa aaaagaaatg caataaaaat aaataagaag ctcattaaga
    22621 tttttctaaa ttattcctca ttataaaatt tcaagtgttt ttttattttg agttttactc
    22681 tcccgtaagc gctcattact tgcttgtgat ccattgctaa acattcagcc atgtctacaa
    22741 aatcaacgcc ttgcatataa taatgaaaaa ttttagcttc tatttttgaa aactggattt
    22801 cgcaattttc gattgcttct tttaataaaa gatgctgaat tgctaaaggt tcttgcaatg
    22861 tgatctctgc taaaaagtct ggtccttctg tctctatttt ttggtcgatt gagacttcat
    22921 ctttttgatc acgacgcttc agcgcgttct gcttcctcaa cagagaatag atttgattgc
    22981 ttataacgct tttataataa cttccaaagc taacaccttt gcttttttcg taagttctca
    23041 atgcctgata taaagcgatc cttgcttctt gttcccaatc ctcagaaaca taatttctta
    23101 aataataggt gtttttcaaa cgtagtaaaa gtggaaaata tttttgatac agggcagcaa
    23161 atgcttcttc gtcaccatta cgtgcagcgc gcaataactc ctcagacata aaataattcc
    23221 tccataaatt cgtttatgga ggaatcttat catcaatgat tcatcgaact gattagaacg
    23281 atatgttatt tattttttct cattaaatcg tccaattttt gggacaattt ttttaactgc
    23341 tcttcattcc atggagaatt acgtcggaaa tcaataaaat gcatatcttt attttcttgg
    23401 gctattgttt tttccgtttt ttttatcgtc ttatataatt cataagcaga agttcgtaat
    23461 gctccttggg aaaagatcat ccactgttct gctaaatcgc ttgtcgccac tgtcacttgt
    23521 gtcaaacggt cattcagctg accagcgatt ctctcgatat aactgtcagc cgtttcgtct
    23581 tctttcgtaa aaacaacatc caactggtat ttcttataat tttgttggat gcccggaact
    23641 agttgggcat cgaagacaac gatgacttcc attccttcat atttcgcata atttgataaa
    23701 cgatgtaaaa gagcttctct tgcatccgcc attttgtcct gctttttaag ctggacaagt
    23761 tccggccacg aaccaatcat gttgtagccg tctacaatca acagctgttt tttcatggtc
    23821 tactccccct gacgttggga aaaagcctga tacataagca aaccagcagc aacactggca
    23881 tttaagctct ggacgtgccc ggtcatcggg atcgtcagca attcatccat ttcttttttc
    23941 aatcctggac tcattccttt gccttcatta ccaatgacta aagcaattga tcctttggca
    24001 ttccattttt ggaagtttgt gccggtcata tctgtgccaa atacccaaaa tcctgtttct
    24061 ttgagctgtt gcacagcttg taccaaattc gtcacgcgtg caacagggac atgttcgact
    24121 gccccagtgg aagtctttgt tacgataggt gtgattccaa ctgctcggtg ttttggtatg
    24181 atcacaccat cgacgccact tgcgtctgct gtccgtaaaa tcgacccaaa attgtgtgga
    24241 tcttcgatgc tatccaaaat caaaaagaag gggtcttctt ttttctcttt tgttcgttca
    24301 atcagttggt caagggataa atattcataa ggtgtaatcg caagaacgac tccttgatgc
    24361 acgccgtgat cgctcaaagt ttctaatttt tgtttaggaa cccatttgac tggcacagct
    24421 tgttcacgtg cgatttcttt cagttcttct actttttctc ctcgtgaatc ttcttgaaga
    24481 aagagtttat tccctcgccc ttgttgtagc gcttctactg cggcatggtg cccaaagacg
    24541 aaattatctt ctaatgcttc ttcattttga tcagaaactg actgatttcg tccagtttgc
    24601 tttttatttg aatatctatt ttgttttttg tcttcaaatc cacgtttcga ttgatgtttg
    24661 tttgttcttt ctttacccat ttttttcacc aactttctga atacaccagc ggatcaattc
    24721 ttccatccgc tcggtttgtt ttgtcaaatg cagatagccc atgagcgctt cgaaccctgt
    24781 tgcgacccga tacgtcgtaa catcagcatt ttttgcgctc gtatggcttt tagcatttct
    24841 tcctctgcga taataaagtt cttcttcttc tgtcaaaaga tgttcttcca gcatttgctg
    24901 aatcaaaaag gcttgtgcat tcgcagaaac ataattcgtt gccgcacgat gcagcttatt
    24961 gggttttgtt tctccttgat caatcaggtg gtcacgaaca tagatttcgt aaatcgcatc
    25021 tccaacataa gccaaggcta aaccgttcaa ttgtgtgtaa tctctcatgc ttctcttctc
    25081 catcgggttc cttgcggtgt atcttctaat aagatccctt tttctttcaa caaatcacga
    25141 atttcgtcgc ttcggacaaa atcacgattg cttcttgctt gatttcgttc ttcgatcaat
    25201 tgttcaatct cttcatctaa taactcttct gctgtaaata aaataccgaa gatcgaaagc
    25261 cattgcgaga ataaagcttc tccttgtgcc aagacagcgg cagaaacttt cggctggtct
    25321 agataagtgt tcagccactt agcaagctca tagaccactg tgatcccatt tgctgcatta
    25381 aaatcatcgt ccatttcttc gatgaatcgc tgttctaaat tttctaacaa agcgatttta
    25441 tccgcatcat ctgccaaatt ctctgaggca gtttcttggc ggaatttcaa attgtcaaac
    25501 gtattcttca gtcgttgtaa attggtggct gcttctttca tcgtcgtttc actgtagcgg
    25561 atcggacgac ggtattgtgt ggtcgccatg aagaaacgca agacttgtgg atcaacgttt
    25621 ttgatcattt catgtacagt gatgaaattc cctagagatt tactcatttt ttcatcgtct
    25681 tcgccaatcg ttacatagcc attgtgcatc cagtaattag cgaatttttt ccctgttttc
    25741 gcttcacttt gtgcgatttc attttcatga tgaggaaatt ctaaatcttg cccgccacca
    25801 tggatatcga tcgtttctcc taaatgtttt gttgccataa cggaacattc aatatgccaa
    25861 ccgggacgtc ctttgcccca tggtgaatcc caagaaatct cgccaggttt tgcttgtttc
    25921 cataaagcga aatctaatgg gtcttctttt tgctgctgtt cttcccctgt acgctgactt
    25981 gctccgactt ccagttcatc gatggattgg tcacttaatt tcccataatt ttcaaattta
    26041 cgggtacggt aatacacatc acctgaagat tcataagcat agcctttttc aaccaacact
    26101 tgaataaatg ctaaaatatc tggcatatga tccatgactc ttggatgcag tgtagcaggt
    26161 tcgacattca acgctttcgt atcttcttca aatgctcgga tgaaacgatc agcaacttct
    26221 ggtgctgtaa tacctaattc gtttgctgta cggatgattt tatcgtctac atccgtgaaa
    26281 ttcgatacga aatcgacttt atagcctcga tattcaaaat agcgtcgaat tgtatcgaaa
    26341 gcaatggtgc tacgagcatt tccgatatgg atataattat acacagtcgg tccgcagaca
    26401 tacataccga catgtccctt ttgtataggg atgaattctt ctttttttct ggtcaatgta
    26461 ttgtagattt ttatcattct gatctcctca ctttttctcc tttgattcga acgacttttg
    26521 ctggtactcc taccgctgta gcgtcgtctg gaacatcttt caacacaacg gcacctgcac
    26581 cgattttggc gttttttccg atcgttaccg gtcctaatat ctgcgcattc gcagagagca
    26641 tggctccttg tttaacagtt gggtgtcttt tacccgtttc ttttcctgtg ccgcctaatg
    26701 ttacgccatg gaataaaatc acatcgtcct cgatttctgc ggtttcgcca atgacgattc
    26761 ccattccatg gtcgatgaac acgccagttc caatcgttgc tcctggatgg atctcaacac
    26821 cagttaggaa acgccagaat tgagcattga tcttcgccaa taaaaagagc cggtgctgat
    26881 ataaaaaatg agagaaacga tgccaaaaca aggcatgaaa accagggtat gtcaaaacga
    26941 tctcagctgt cgaacgtgca gccggatcgt ttctctttgc tgcatcaatc gctcgggtaa
    27001 accaactcat gactttccac tcctttcgta agaattttat gtaggaaatc atcttcttat
    27061 aaagaaaaga agcgcctttt aaataagttt ccttatcaaa agacgctttc cgcgtggttc
    27121 cacttttctt cataatcaat gattatctct gacagctaac gcctgttata cgttcttggc
    27181 tactttgttt cctataaaac agtttttcct gttttctgtg tttcgccaag accactccca
    27241 gaggcatttc ggcaaccatt cattgatacc ttgcaccacc cggtatctct cttgtaatga
    27301 tcagctgctt acttttttct gttcatcgtg tttagttcag tacttgattt aaatgtgcta
    27361 atgatttttc acgaccaagc aattcgatcg tttcaggcaa ttctggacca tgcatttgtc
    27421 ctgatacagc tacacggatt ggcatgaaaa gattttttcc ttttacgcca gtttcttttt
    27481 gaacagcttt gatggcagct ttgacagttg gagcatctac tacttccatt tgttctagct
    27541 gtgctttgaa tgcgtggaga acagtaggaa ctgtttcacc agcaagtact tcttttgctg
    27601 cttcattcaa tacaggatgt tcattgaaaa atagcgtaga cagatcaacg atttctgcag
    27661 catagctcat ttgaggttga tacaggctaa cgatcttctt cacccattcg attgtctttt
    27721 catctgggtt ttctgctaca cgtccatcag cgattagata aggcagacac atgtcagtaa
    27781 atgcatctag atccattgct ttgatgtaat ggttgtttac ccattgcagt tttttcgcat
    27841 cgaaagctgc gggtgattta cttaggcgtt ttggatcgaa cattttgatc aattcttggt
    27901 gttcgaagat ttcgtcttcg cccacaggtg accagcccaa taatgcaata aagttgaaca
    27961 ttgcatctgg tagatagcct aattcgcgat attgttcgat aaattgcaag attgattcgt
    28021 cacgtttgct tagtttttta cctgtttcac tgttgatgat caatgtcata tgtccgaagg
    28081 ttggtggtgt ccagccaaat gcttcataga tcatcagttg ttttggtgta ttggcaatat
    28141 ggtcatctcc acgtaaaacg tgagtgattt tcatcaaatg atcatcgacc gcaacagcaa
    28201 aattataagt tggcatacca tcgcgttttt ggatgacaaa gtcgccaccg atattatcgg
    28261 attcgaacga aatagcgcct ttcaccatat ctgtaaatgc gtattctgta ttgcgaggca
    28321 cacggaaacg tacaacagat tctagacctt gtgcttcttt ttctgcttgt tcttcaggtg
    28381 tcaagttcgc acatgttcct gcgtaatgag gcatttctcc tcttgcgcgt tgtgcttccc
    28441 gttctgcttc taattcttct tctgtgcaat agcatttgta tgctcgattg ctagcaagca
    28501 gctgatcaat cagcggttga tagatttctt tacgttcaga ttgacggtaa gggccgtatt
    28561 ctccaggatt ttcaggagat tcatcccaat tcattcccaa ccaagcaagg ttttccaact
    28621 ggcttttttc gccatcttcg atattacgtt tttggtcagt atcctcaata cgaataataa
    28681 agtctccatc attgtggcgg gcaaacaaat aattgaataa tgcagttctt gcatttccaa
    28741 tatgcaggtg cccagttgga cttggtgcat agcgtacgcg tactttcgtc attttcttcc
    28801 tcttctttca aactagactt tgactaacag caaaaattcc gtcagttacg gcttctcaaa
    28861 tatcatttat ttaaagccac tcagcacaaa ttttaccttt tctaaggtaa atagtaaagc
    28921 caactggttg aatttcctta ccagttggct gaatttcttt tttattttga ttgtttagtc
    28981 tttttctctg tctctttttt attgtcgatt cctcgtcctg catgtgcagg tttagcaaag
    29041 atcatgcgtc cagcagctgt ttgaagggca cttgttacaa cgacttcgat acgttcattc
    29101 atgtaatgct gtccatcttc tacgacaacc atcgtgccgt catcaaggta ggctactcct
    29161 tgttggcgtt ctgtcccggc ttttactact agaacattca tcgtttcacc agggatgacg
    29221 actggtttta cggcatttgc caacgcattg atattaagaa caggtacatt ttggaattca
    29281 gagactttat tcaagttata gtcattggtt acaatgacac catctaaaag cttagccaat
    29341 ttgatcaatt tgctgtctac ttcactgata tcttcaaagt ctccatcgta catttcgaca
    29401 gatataccct cttctttttg caaggcattt aggatatcta atccgcgacg accacgcaca
    29461 cgtttcaaac tatcccctga gtccgcgatg tattgtagtt cgtaaagaac aaaattaggg
    29521 atcatcaagg ttccttctaa gaatccagtc tttgtaatat cataaatccg accgtcaatg
    29581 atcacgcttg tatccaagat tttatattta tggaaatttt ctcctgattt tcgttctaac
    29641 agttgactct caacttgact agctgtttct tgctcgattt ttttgcttcg tgaaccaaaa
    29701 actttcttcc attcttcgat tcgtgtcgtt cccattctca atcccagata gcctaagatg
    29761 atcatcagta aaatcggcaa tacactattg acgaatggaa tttccatatt gtaaagaggg
    29821 gtcgagatca caacacctaa agtcaatccg atgatcgcac cgatcgcacc gaagagaaga
    29881 taagtcaagc tgacctcact tagtttttgt tctacttgtt tgataatagc tgagatatgt
    29941 ttggccaaca gcaaagataa taaaaagaaa ataagtgcgc ctaacaggct gttggtaaat
    30001 gtattattca gccatccgtt tgactgttga ccgattgcct gccaagctga gggtaaaaat
    30061 gaaataccca agcttgcgcc gacaatgatc atcagcaaag taatgacacg tttttgcatc
    30121 gtttttcctc cgtttcgaca atcatttatt agttagcgga acacacgctt caacgtttca
    30181 gccaaagttg ctactccaac tatctcgatt ccttttggcg cttcccagtt acctaagttg
    30241 tttttaggta ggtatacttt tgtgaagccg agtttttgga cttctttgac tcgttgttca
    30301 atatgactga cacgtctgat ttctccagtc agtccaattt caccgatgaa acattccgtt
    30361 ggctgtgttc ctttttcttt atagcttgaa gcaatactga cagcgatagc taaatcaatc
    30421 gctggttcat ttaattttac cccacctgca gcttttaagt aagcatcttg attctgaaga
    30481 agcaacccag ctcttttttc cagcactgcc atgatcagag atacccgatt gaaatcaaga
    30541 cctgttgttg ttcgtttggc atttccgaac atagtaggtg tgactaatgc ttggatctct
    30601 accaaaattg gacgtgtccc ttccattgcc acaacgatag cagagccagt tgcaccgtct
    30661 aggcgttctt ctaagaaaat ctgtgaagga ttagcgactt cttccaatcc atgctcatgc
    30721 atttcaaaaa tcccaatctc attcgttgag ccaaatcggt tttttactgc tcgcaaaatc
    30781 cgaaaactat gatgttgttc accttcaaaa tataacaccg tatccaccat atgttctaac
    30841 attcttgggc cggcgatcga gccttctttg gtaacatgac cgacgataaa aatggctatc
    30901 ccatttgttt tagcggtttt gagtagttct gcagtggttt ctcttacttg gctgacactt
    30961 cctgccacac ttgtgatgtc tggctgcgtc atcgtttgga tggaatcaat gataacataa
    31021 tcaggggaga tatgttcgat ggcacgactg atttcgttca tatctgtttc agcgtataga
    31081 taaaattctg tgttgatact tccgaggcgt tccgcgcgta attttatctg ctctgcgctt
    31141 tcttcgccgg atacatataa gacttttccg cctatggctg ctaattgctg agaaacttgt
    31201 aacagcaaag tggatttccc gatacctgga tcgccaccaa tcaagaccat agaccctggc
    31261 accacacctc cgcctaacac acggttcagt tcttctaatt ttgttttgat ccgaggttct
    31321 tttttaggga cgacgtctgc gatttttgtt ggttttgctt tttctcctgt caaacttgtc
    31381 cgagttctgc ggtccgttgt atcttgttcg atttcttcga ccatcgtatt ccattttccg
    31441 caatttgggc agcgtcccaa gaacttaggc gacacatacc cgcaattttg gcaaacaaat
    31501 tgtacttttg atttttttgc cattgtaccg cctcctttta tcctaatcat gagacattaa
    31561 atcaagctta agtatcttta acgttttatt tactggaaga accaaatccg ccttgacgtt
    31621 gagcagtcgt ttgatcttga tctgctttta aaaacggcaa aaagatccct tggccgatac
    31681 gctcgccttt tttgatcact acatccttga aaccaaagtt ggtgaattgg aacatgatat
    31741 ggccttcatt tgcctcatta ttgtaataat cactgtcaat cacacctact ccgtttgtca
    31801 acactaaaaa ccgcttcaac ggattgcttg aacggttagc aagctgcaaa aattcatctt
    31861 ctcccatgta agctttgatt ccagtaggca cgagggttgg tttcaattgt ttttcatttt
    31921 ctgatacatc ttttttcaat ccatctgcga ctgtttccaa cccctttttc cagcctgctt
    31981 tccagatact tggaatcacg acctcttctg ctgcttcaaa atcatagcca gcagcatgat
    32041 gtgtagcgcg ctgcggtaga ttgatatttt gatctttata tttagaaata acttcaaatc
    32101 ctctttttct caccggtttt cct
//
LOCUS       DAPBAF010000036        28603 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.036, whole genome shotgun sequence.
ACCESSION   DAPBAF010000036 DAPBAF010000000
VERSION     DAPBAF010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 28603)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28603)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28603
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.036"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            237..1877
                     /locus_tag="RD451_001904"
     CDS             237..1877
                     /locus_tag="RD451_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent malic enzyme"
                     /protein_id="HDT7567161.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAVFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAATILEKYEDKITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQTILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     KGLTPGQIPFARKRSEFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQKLNREEITDIKEAVESAKWVPEYKSLED"
     gene            2031..3353
                     /locus_tag="RD451_001905"
     CDS             2031..3353
                     /locus_tag="RD451_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HDT7567162.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFLDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRNVKPSIPQLGVGLMVSL
                     TFFILGQICNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(3415..3846)
                     /locus_tag="RD451_001906"
     CDS             complement(3415..3846)
                     /locus_tag="RD451_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7567163.1"
                     /translation="MLREMRLGDAEALREINAEQLGYDVPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKHAEKRGIGKALMTGVEEA
                     KRRGISAIRLNSAEYRVEAHRFYERIGYHSDKMQKRFLKIL"
     gene            complement(3910..4746)
                     /locus_tag="RD451_001907"
     CDS             complement(3910..4746)
                     /locus_tag="RD451_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HDT7567164.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQAIVIVVLLINLYNAFVILQTLEGSGFKQVKITEKSF
                     FK"
     gene            complement(4936..5238)
                     /locus_tag="RD451_001908"
     CDS             complement(4936..5238)
                     /locus_tag="RD451_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HDT7567165.1"
                     /translation="MTEHNHSHEHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEE"
     gene            complement(5264..5695)
                     /gene="ruvX"
                     /locus_tag="RD451_001909"
     CDS             complement(5264..5695)
                     /gene="ruvX"
                     /locus_tag="RD451_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HDT7567166.1"
                     /translation="MRVMGLDVGSKTVGVAVSDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            complement(5692..5958)
                     /locus_tag="RD451_001910"
     CDS             complement(5692..5958)
                     /locus_tag="RD451_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HDT7567167.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPAYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            complement(6212..6937)
                     /locus_tag="RD451_001911"
     CDS             complement(6212..6937)
                     /locus_tag="RD451_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HDT7567168.1"
                     /translation="MSKKTTKAIVGIVAAVIAGALGISTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            complement(7303..7373)
                     /locus_tag="RD451_001912"
     tRNA            complement(7303..7373)
                     /locus_tag="RD451_001912"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7339..7341),aa:Gly,seq:ccc)
     gene            7490..8242
                     /locus_tag="RD451_001913"
     CDS             7490..8242
                     /locus_tag="RD451_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HDT7567169.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            8258..8737
                     /locus_tag="RD451_001914"
     CDS             8258..8737
                     /locus_tag="RD451_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HDT7567170.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(8988..10568)
                     /locus_tag="RD451_001915"
     CDS             complement(8988..10568)
                     /locus_tag="RD451_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HDT7567171.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(10561..11304)
                     /locus_tag="RD451_001916"
     CDS             complement(10561..11304)
                     /locus_tag="RD451_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7567172.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFVFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            complement(11480..12256)
                     /locus_tag="RD451_001917"
     CDS             complement(11480..12256)
                     /locus_tag="RD451_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7567173.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            complement(12504..13340)
                     /locus_tag="RD451_001918"
     CDS             complement(12504..13340)
                     /locus_tag="RD451_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HDT7567174.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            complement(13351..14280)
                     /locus_tag="RD451_001919"
     CDS             complement(13351..14280)
                     /locus_tag="RD451_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HDT7567175.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            14472..14825
                     /locus_tag="RD451_001920"
     CDS             14472..14825
                     /locus_tag="RD451_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HDT7567176.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            complement(14899..15555)
                     /locus_tag="RD451_001921"
     CDS             complement(14899..15555)
                     /locus_tag="RD451_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HDT7567177.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            15781..17715
                     /locus_tag="RD451_001922"
     CDS             15781..17715
                     /locus_tag="RD451_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HDT7567178.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            complement(17801..19024)
                     /locus_tag="RD451_001923"
     CDS             complement(17801..19024)
                     /locus_tag="RD451_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HDT7567179.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(19018..20916)
                     /locus_tag="RD451_001924"
     CDS             complement(19018..20916)
                     /locus_tag="RD451_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HDT7567180.1"
                     /translation="MVVKRGENTMKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQ
                     IDYIHQGVGYGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYW
                     GEIHERDQRMVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQF
                     FKIIVGTIIQKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYG
                     LIYSVLEPEKPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAML
                     WADLLPFKLGEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLW
                     LNKIFLLLALPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPN
                     FHTLTNEKYLKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKT
                     YGQFIVRNNVRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLY
                     ETGFAIECSPEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLM
                     TWENTFIPGLEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKN
                     NKKRLKLC"
     gene            complement(20910..22028)
                     /locus_tag="RD451_001925"
     CDS             complement(20910..22028)
                     /locus_tag="RD451_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HDT7567181.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            complement(22111..22944)
                     /locus_tag="RD451_001926"
     CDS             complement(22111..22944)
                     /locus_tag="RD451_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDT7567182.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVSATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            complement(22937..23854)
                     /locus_tag="RD451_001927"
     CDS             complement(22937..23854)
                     /locus_tag="RD451_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDT7567183.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            complement(24081..25205)
                     /locus_tag="RD451_001928"
     CDS             complement(24081..25205)
                     /locus_tag="RD451_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HDT7567184.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            25388..26296
                     /locus_tag="RD451_001929"
     CDS             25388..26296
                     /locus_tag="RD451_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7567185.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
     gene            26437..28050
                     /locus_tag="RD451_001930"
     CDS             26437..28050
                     /locus_tag="RD451_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDT7567186.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
BASE COUNT         8893 a         5622 c         4868 g         9220 t
ORIGIN      
        1 ttctatttat ctatctaaca tatcctttat tcttctactt ttctttcttt agcatataag
       61 agatacgcat agtaatcaag caaggattgt tgatataaaa agaacaaata ccgctatttt
      121 gatttctttt gactctatta ctcatataaa taaaatttat tatacctgct ctttttgact
      181 atatcctcat ctgactccta tacttcgttt gtattaaaac ttaggaggaa tcattcatgc
      241 ttacagggct aaacttatta aataatcctt ttctaaataa aggaacagct tttacaaaag
      301 aagaacgggc aaaatacgga atcactggta tgcttccaag tactgtccaa acattggaac
      361 aacaatctgt ccaagcttac ggtcaatact taagcaaaca gaccgatttg gaaaaacgta
      421 tcttcttaat gaatctattc aatacgaacc ggacattgtt ttataaattg atgggcgaac
      481 atttagttga attcatgcct gtcgtttatg atcctgtcgt tgcggattca atcgaacaat
      541 acaacgaaat tttcttgaaa ccacaagatg ctgtatttct ttcaatcgac gaaccagaaa
      601 atatcaaagc aagtttgaaa aacgcagcag atggacgcga cattcgtttg atcgttgtga
      661 cagatgcaga aggaatctta ggtatgggtg actggggtgt gaacggtgtt gacatcgcta
      721 tcggtaaatt gatggtctac actgccgcgg ctggtatcaa tcctgcacaa gtcttgcctg
      781 tatcaatcga cgctggtact aataacgaag aattattgaa taatccatta tacttaggga
      841 atcgtcatgc tcgtgtagaa ggcgaaactt actacgaatt cattgatcaa ttcgttcaat
      901 cagctactga attattccca gaattgttat tacattggga agattttgga cgaggaaatg
      961 ctgcaacgat cttagaaaaa tacgaagata aaatcactac tttcaatgat gatatccaag
     1021 gcacaggaat cgttgtacta gctggtgtat taggtggatt gaatatatca ggtgagcaat
     1081 tgaaagatca aacgatcttg acatttggtg ctggtactgc tggtgtaggt atcgcaaaca
     1141 tccttttaga tgaaatgatc cgtcaaggtg tacctgaaga agaagcacgc caacatttct
     1201 atcaagtaga taaacagggt ttattgtttg aagatacaaa aggattgact cctggtcaaa
     1261 tcccattcgc tcgtaaacgc tcagaattca ctaatgctga tgaattgaca aacttagaag
     1321 cagttgtaaa agcaatccat ccaacgatca tgatcggtac ttctacccaa cctggagcat
     1381 tcactgaaga aatcgtgaaa gaaatggcgg ctcatacccc acgtccaatc atcatgcctt
     1441 tgtctaatcc aacaaaattg gcagaagcaa aagcaaaaga tttgattgaa tggacggacg
     1501 gaaaagcttt agttggaaca ggtatccctg ctgctgatgt ggaatataac ggtgtaactt
     1561 accaaatcgg tcaagcaaat aatgcgttga tgtacccagg tttagggctt ggtttgattg
     1621 cttcaacagc tacacgagta aatgctgaaa tcatttctca agctagtcga gcattaggcg
     1681 gaatcgttga tgtaacaaaa ccaggagcag ctatcttgcc tccagtagca aaaatcactg
     1741 aattctctca aacgattgct gaaactgtcg caaaatcagt tgttgcacaa aaattgaatc
     1801 gtgaagaaat cacggatatc aaagaagctg ttgaatctgc taaatgggtt cctgaatata
     1861 aatctttaga agattaagat tgttatagta aaagaacata cagaaacttt gtatgacgtc
     1921 taaaaagaaa aaagcgactg cggcaaaaca gcagccagcc aactactgct cttttgccgc
     1981 ttctctttgg cttttttcat acgatacaga ataagaaagg atctgtaaaa atggcacaaa
     2041 aaacaacaac cgcaactgca gttgaggaaa agaaaaaaga agggttttgg tcaacaaaaa
     2101 ttaccggcgt aagtttgccc ctttatttga tcatggtcct tgtcctgatc attgcaatgg
     2161 ctttaggaaa attaccgacg aatatgattg gcccaatcgc tgttttggtc attttcggta
     2221 atttatttca ttttatcgga acaaaaatcc ctatagtcaa aagttattta ggtggtggct
     2281 ccgtttttgc gatctttgcc tctgccgcga ttgctacatt tgggatctta cctgagtatg
     2341 tagtaaaatc cacagaaaac tttgtcagca atatgggctt tttagacttt tatattgctg
     2401 ccttgattac tggtagcatc cttggtatga accgtaatct attgatgaaa gcttctgttc
     2461 gttttattcc cgttgcactt atttcaatgg tcgtctcctt ttttgccgta ggactcgtag
     2521 gtatgcttat cggaaatggt tttgcaaatt ccgttttata tatctcattg cccgcaatgg
     2581 ctggtggtgt tggagccgga gctgtacctt tatcaacgat ttatgcaaat gttttaggta
     2641 cggacgcttc ttctatcatt tcccgcctga ttcctgcgac agcaatgaca aatgtcctag
     2701 ctatcattgg tgcagcgtta gttgctcgtg cgggacaatc aatgccaaaa ttcaacggta
     2761 atggtaaatt aatggaaaaa ggcgaccttg gcgatggaaa acctagaaat gtaaaacctt
     2821 ccattccaca attaggtgtc ggtttgatgg tatcattgac tttcttcatc ttaggacaaa
     2881 tctgtaacta ttttgttcct aaagtccatg cttacgcatt catgatcatt atcgttgtta
     2941 tctgtaaaat cgcaaaccta ttaccagaat attacgaaga tgcagctatc atgttcaaca
     3001 acttgattgt caaaaacttg acagcagctg ttcttgccgg tatcggtatt gcgttattga
     3061 atctaaatgt attggcttct gctttgacat ggcaatttgt tgtcttatgt ttgacaagtg
     3121 ttatcgcgat ttcagtagtt tcaggatttg tcggtcgttt gtttggttta tatccaatcg
     3181 aatcaactat tactgctggc ttatgcaaca actcgatggg tggtacagga aatgtagctg
     3241 tcttatctgc agctaatcgg atggaactta ttgcttttgc tcaaatgggc aatcggcttg
     3301 gtggtgccat cgttttgatc atctcaggtt tcttgatgca attactttct tagtcaaaaa
     3361 aaatacctga tcatcaagta tcggcttgat gaccaggtat tttttgataa aaatttacag
     3421 gattttcaaa aatctttttt gcattttatc ggaatgataa ccgatgcgtt cataaaatcg
     3481 gtgtgcttct actctgtatt ctgcagaatt aagtcttatt gctgatattc ctcgtctttt
     3541 cgcttcttct acgccagtca tcaaggcctt tccgattcct cttttttcag catgtttaga
     3601 cacagcaagt gccataatat tgaacatcgg atcgctgaaa atcgattcat aggactccgc
     3661 ttgtacatag ccagctgctt ttttagaagt aggatcttca tagaccaaga aaaaattttt
     3721 ttctggctcc ttcaacagtt tcttcatttg tctcaccgta acggttaatg gtacatcata
     3781 tcctaattgt tccgcattga tttctcgtag tgcttctgca tctcctaaac gcatttcccg
     3841 caacatccaa atcaccagcc aatttttatt tttttaaatg aattttttta tcacagtata
     3901 ctcctttttt cacttaaaaa aagacttttc agtgattttg acttgcttga atccagatcc
     3961 ttctaatgtt tgcaagatga cgaaagcatt gtaaagattg atcaaaagaa ccacgatgac
     4021 aatcgcttga aaaataaagg tcactttttt tggagacaaa accctgctaa atcttgctcc
     4081 ccacaaacct ccaataacag cagcggggat aacataaaac aacatagata aatcaaagcg
     4141 cataaagcta cttgttaaag caatcgttac caattttgcc agttgagaaa agaaaatcgt
     4201 agatagagaa tatagtgttg cttcttttat tggcaatgca aacatcagca tcaacaaaga
     4261 aacattgact ggtccaccac caatacctaa aaaactagct aaaaagccca gaaccccccc
     4321 acatataagg taccaagtcc atgacgtcaa atgaaatttt ggctgatgat gcttggtgta
     4381 gaagaacgca aaaaccaagg tcaataccgt caaaaaaatt tggatcagct gcacatgctt
     4441 ctcgttttca aataactgta aaaaaacttc gaatacaatg ttgccgacta ctcctccaac
     4501 aacagctcca ctagataccc aaccgacaat ctgccaattc agtgatttcc cgcttgatac
     4561 ttgtcgcaca gtcgaaacaa tggacatcgt gaataccgca actgttgagt aaaaagaaat
     4621 ccctgcaaca gaatgggcgc cgataagatc aagaatcggt ttgatcaaca cgcctccacc
     4681 catcccggaa atagcgccaa ctgtgttcgc cagaacgatc accacaaaat aaatcagacc
     4741 aatcatcttg tatttccttt ctcttgttta tatcttttag cgattgttac tcttttcttt
     4801 tattatacag taaaagaaac aaacgaggct tcgaaagctt ttctactttt taaggaaatt
     4861 tagtgctaaa cgaaaaaacc gggctctact tttcagagag tccagctttt cttacacctt
     4921 atcgattctt ttgttctatt cttcttccgc catgaatgta ttgaatactt cttcgatcat
     4981 atcccattct gcgtctgttt cgatttgttc taactcgcct tctgttccat cttcgttttc
     5041 gatgtatgca taagcttgta attctacatc ttcatcttct gaaacaccag ctggatataa
     5101 aagaacatag ttacgtccaa attcttcttg tccgtcaact gttagcaaga tttcgtataa
     5161 tgtttcattt ccttggtcat ccaccaatgt gatgtgttcg tgtccttcgt gttcgtggga
     5221 atggttatgt tctgtcataa gattacctct tttcttttta ttattaaaat aattgcttac
     5281 ctgagccgtc taaataattt tgtaaaatca tcacagctgc taatttatcg atgacttttt
     5341 ttcgtttcgc tcttgaagta tttgcctgct ctactagcat acgttctgcc tgaacagtgg
     5401 ttagtcgttc atcttgataa tcaaccggca aggagaatag ttctttgatc ttctctccat
     5461 atgacatgga agcttctgcc cttggtccga tggaattgtt catattctta ggtaatccaa
     5521 ctacaaaacg gtctacttcg tactgcgcca ctaattcctt caaccgatca aaaccaaact
     5581 cttcttctgc ctcattgatt cgaatgattt ctactccttg agctgtccag ccaaagggat
     5641 cgctcacagc aacgcctact gtcttagaac cgacatccaa gcccattact ctcataaatt
     5701 cactccatga tttgagaggt agtctttgac aattacttcc atgatttcat cgcgttcgtg
     5761 acggcgaatc aaatttcgtg catcacgata acgaggaatg taggccgggt ctccagaaag
     5821 caagtagccg acaatctgat tgattggatt gtagcctttt tcttccaaag cccgataaac
     5881 aatcgctaat gtttcgctca cttctttttt gcgactatcg tcaaaaccaa aacgtacggt
     5941 ttcatctgta aaacccatga ttctacacct ctttcccgca aggtaattcc agcttacctt
     6001 ctacaccctt attttactcg aagaaaggga aaactacaaa caaatattcc aaacttctga
     6061 ataaattaag aaacacgatt tgtctgattt ttcctttttt ctgtggcttt ttcaaaagcc
     6121 ctctttccat aaagtatacg ctatatttct ttgaaagtat gtttttacac aattttttca
     6181 taaagttcat aaaaaattcg aattgctgct actaattctt cgttttcgtt gcttgccctg
     6241 tctcataatt gatggtgtag ccatcttgaa cattgtagat aaagacattg aattcaattt
     6301 ttttgtcttc aatgctttct gcttccaact gcacacctct tgctaccagt tcatttccct
     6361 cgaaatgagg agtgacacga tagcgtacat gatgatttgt ttccttgata tatgccgcaa
     6421 tatcattttc gtgggcaagc atgtacggag cattcaacga acgtgtccct gtcattaagt
     6481 ttttaatgtt attattttga ccagtcaact ggaaaccaat caaatggctg cggttgtata
     6541 accattgtcc gtcacttaat ttcttttgtt tccaacctgt cggatcaata tacaaaggtt
     6601 ctctcttttc agtaggaaac aagtcttttc ccaacatcgc attggcttgt cctactctgt
     6661 tcaatttgtc tatatttgaa tagctttccc atgtcccttt ggaaagacta agatcctctt
     6721 ttgtaaactc cggctgattc ccattgattt ctatttcttg atgttttcca tcatattctg
     6781 gcacatccgc tacttgagaa gcttgcggtg tggaatcaaa aatggttgta atttgttgga
     6841 agatatctga atctttttgt gtggtggaaa taccgagtgc ccctgcaatc acagcagcga
     6901 cgatccccac gatcgccttg gttgtttttt tgctcatttc tttactcctt tactaacagt
     6961 tccctaaatc ttaacatatg ttcccctata aataaatact ggaaagaaat agaaacagta
     7021 aaaaaataaa accagttttt agacggctta agaatacaaa aaaagagacg gattcatcgt
     7081 ctctactcaa tcacaaaaca ctatttacaa ggtatttatt atcattcaaa aaatttttct
     7141 taatactcaa aactaaacgg cttctgtacg acctcttggt aaacagtgtt caaaagcttg
     7201 catctgcggt aataagtcca accaagtcaa aaacataaga agcttttttg cttgactatt
     7261 cttattactt gatgcagggc agctttttca cagcctcttt taagcgggtg acgggaatcg
     7321 aacccgcgac atcagcttgg gaagctggga ttttaccact aaactacacc cgcgatacaa
     7381 aaacagtata cgcctctttc actccttcct caagtttttt tattctttac gcttccgata
     7441 tgttttgtag taaaataaaa ctaatcaatc aattattgga gaagatgcta tgacgggaaa
     7501 agaattagat ctgttgctgg acacttgttt actcgctggg aaaatcatga tggaaagcaa
     7561 tgcggagatg tatcgggtag aagatacgat gagtcgaatt gctttagctt ctggaaattt
     7621 ccgtttggtc agctatgtca ctcaaaccgg tctctttatt ggtcttgatc gtacctcgac
     7681 catccgaatg gaacaaatta ccaaccgttc gattaattta gaaaaagtag taaaagtaaa
     7741 tgatctttca cgtaaatatg ttgcttcaga gctaacatta gaagaacttt actgcgaact
     7801 gcaagcaatc gaccgagacc gttctttctt tcctgtctgg ttgcaaatcg ttagcgcggc
     7861 agtgatcagt ggaacaatta tggtgttatt tggcggaaag atgaccgatt tacctgtgac
     7921 tttagtcatt ggaggattgg gatacgcagc ttatctatat agtttgaaat tttttagaat
     7981 caaattttta tcggaatttt tatcttcttt attgattggc atagccgcta tctacagcgt
     8041 acgttttggc ttaggaagca atcaggatct aatcattatc ggatgtgtga tgcctttagt
     8101 tcctggagtt caaattacga acgctatccg tgatttgcta gctggacatt atgtctcagg
     8161 agtttctcgc ggaacagaag cgatgatgac tgctacgatg atcggttttg cgattgcttt
     8221 tattttccag cttttttatt aggaaaggaa cacaagtatg gggacgatat ttattcagtt
     8281 ttcttttagt tttttagcga ctgcggcatt tgccgttatt acaaatgtac ctaggcgttc
     8341 attgatttgt tgtggtcttt ctggtgcttt tggctggatg atctactgga tctgtgttca
     8401 aataggcgga tctgctgctt ttggttcatt gcttggttct ttaggagtag cattcatcag
     8461 cgatcttttc tctaaacgtt tgaaaatgcc cgtaacgatt ttcaatattc ccgggatggt
     8521 tcctctagtc cctggtggtt tagcttatca agcggttcga aatctcgtta ctgaatccta
     8581 tcgagaagcg gctcattatg cggtccaagc aattatgatt gctggagcaa tcgctttagg
     8641 tcttgtatta tcagaagtct ttaaccataa catccgtaat ttcaaagtaa agcgtgacgc
     8701 aatcatgatg aaacgaaaaa aacggctttt taaataaacg aagtgtaaca aagaaaaggt
     8761 tgtgaaagag acgttcagcc ttgagcgatg acaaaatatc tcacaaacat tgcgacaagt
     8821 aaccgcagga gcaataagaa gtaattatga gtattaaaaa aagttttgta aaaatagctt
     8881 ctcacatttt tacataaaat tgacttaata ctgagaaact gacttttgaa caccctctat
     8941 ctgtaaaaaa ggggctgcga catgattttt gtcacggccc ctcttcttta ttcaaatttt
     9001 ttccaaaacg ttcgttgata ataaacgatc catagagcgg aaagtattag aactaaaccg
     9061 atcacaggaa tattcactaa ccaaaatgga taaaacaaag ccaacattcc gtataagacg
     9121 ataagaataa tactgatgat caatgaaccc atcatagttg cgactaaacc caaacttcct
     9181 gaacctctgt taaataattg gttaatattg gtccagttca gcagcagcaa ccgataatct
     9241 ctagcgaaat aacgtagtga caataagtag cagccgaata aagaaccaaa tagcaagcta
     9301 gggataaaaa acaaaggcag ctgaaaagac agtccgctta ataatgcgat cccaccagtt
     9361 aaaaaactct gcaatatcca tccgaatctg aacttttctt ttaaatattg gttcatagag
     9421 attggcaaag aacggataaa cagaaaattt tcttgatcca aagaaataag attgctgata
     9481 aaagaagtct gattaactgt taagaaagcc aatgcgatcc ctaccaggaa aacaacaccg
     9541 attaacttat tatctaaatc agttaatttt atttcgcctc ctagggcaaa agcaagaata
     9601 aaaatgattg gagttaacaa ggaagaagaa agaacttgca taatcaaatt aggttctttt
     9661 actaattgag cattgtaact aaataaaagc tgatgcacat tttggttctt tttatgggtt
     9721 ctttttattt tgaactcact gtttgaatca gtcagttgct ctgtaagctt tggtactatc
     9781 agctgtttta cagcaaggaa aaatcccaga gccgtgatag ctagtattcc ccaacccaat
     9841 aaaccttgtt gagaaagtgg ctgactggca gcatcataga atggcaataa tatcgaaatc
     9901 ggatgccgat ctgttaactc attttcaata gtccccgttt gatgattcat ccacatgatt
     9961 ccagcaaatg cgatcagcat cgagctgcca agcaagatac tagaaactgt ttttctatgt
    10021 tttttaaaca ctgctgttcg agccaaacca aaaacaatca aactagccag acaaaaaaga
    10081 ataatcaaaa atagagaaaa caaaaggatt gagataatga tagtaagcaa aatccctaga
    10141 tcagctcgcc atccggttaa aataaacatg actagaagcg gaaaaacaaa aggaatgatg
    10201 gtcaaagcaa ctaccaaaat ctttgctgaa aaaacctgtt cttgtccaaa aggcagaggc
    10261 aaaaatactt gcaggtcatt tccttcaaaa aagatattat aaatgactga tatactttga
    10321 gttaaaccta acataccaaa aagtgccacg taataagtaa agaaacctgg caatttaaca
    10381 aagttcatag caaacatagc aaatccgtaa atcagtaaaa aaatcagccc tgaaaaaaga
    10441 ttttgagaca aaagatagat agttaatcgc tttccctttt ttcctttctc tcttgcttta
    10501 ttcgtgagct gtggattaac atataaaaga ttaactcgaa ttaattctaa taattgtcgc
    10561 ttatacatac ggtccatctc ctgtcgcttg ccttccagcc attttcaaat aaatcttttc
    10621 tagcgtttca tcaggtgagc cattcaataa ttcactaact gccccctgat aaatcaattc
    10681 acctttcttc aaaatagcca gtttatcgca taactgttgt gcggtatcca atacatgtgt
    10741 agaaaaaatg actgtttttc cttttgcggc atgagccttc atcatttctt tcaaatcaaa
    10801 tgctgcttga ggatcaagtc cttgcaaagg ttcatccaat acccaaatat ctggatctgg
    10861 cagcaacgtg ccgatcaaaa tcgttttttg acgcattcca tgtgaaaaac ttgcgattgt
    10921 ttcattttga tgactataca tatcaaaaag cgctgtcaat tctgctaaac gcttttcttt
    10981 tttttgtgtg tctaattcat aggcagctga aatcaagtcc caatattctc cagccgtcaa
    11041 ttgtaaaaaa atatctgggg aatcaggcac ataaccgatt ttttgtttga tactcaatcg
    11101 attttccgtc aatttcattc catctactaa aatcgttccc gatgatggtt caataatact
    11161 aactaaactt ttaatcgtag ttgattttcc ggcaccatta tgtcctaaaa atacaaaaat
    11221 ttccccttgt cttatcgaga gagacaagtc ttttaatgct tgttttttcc cgtaactttt
    11281 acttacattg atgaattcaa tcatttctgt actccttttg tttgttatta ctttttattg
    11341 tacccttcgt tattggtgga gtaaatgtca aaaagagtgc ataacaaaaa aggatagaaa
    11401 cgactaggct gctacttggg ttgttctctt ctacaggaaa acactcttct aacaggtaag
    11461 atatgagtct ttgttttctt taaaatgatt cattttctat cttttcttgc ataaaattct
    11521 ttagtttatc aatacttctc tttcccatct ctagttgttc tccatttgca aatgttacta
    11581 tttcgtttac tctgctaata gatgtaatgt tttcagtatt aatgatataa gcttttaaat
    11641 ctttacataa atactcatat tcgagtgatt ttttatattt tttaattgtg ccgtttacga
    11701 gaatctcttc atctttcaat actaggccta ttttattttt ataacctggc atgctcatta
    11761 gataaaggat ttcatcgtaa tggatatagt gatcgctatt accataacgg acagttgtcc
    11821 accttttttt cgtagcatgt tgaacaggat agttttcttt ttctttcaat aagtaacttt
    11881 ggatgctttt tttatttttt tcataagtga attcttttat caaataacca ctaggcgtaa
    11941 tctttcgatt aataacagtt attgctttat tcggatgaga cgttagataa acaattttac
    12001 acttttcatt cttttctcta agcatttcgc ctagttcgat accgctataa taggcgttca
    12061 aatcgatgtc taggaaaaaa atatctgagg aatagatttc attattttta atgaattcaa
    12121 caaattgtat aacgttcaat ccctgaacga tctcaaattt ccaaggactt aataaaattc
    12181 tggattcttc caaaatttct actagcattt tttcaaaaac caaactatca tccaaaataa
    12241 atatacgcgt taccataaaa agtacctcca ctcgatattt tactatcaaa atcatttcat
    12301 acaacttttc aacatacatg ttaggaataa attgtaattc tcttcacaat cttttccaac
    12361 acctttgaaa ccgatatcaa atactttcag gatgctgctt ctaaaataaa tatcaaacaa
    12421 atgaatacat catgcaaaaa aagccagaca accgacgtcc ttgcgtgtca gctgtctgag
    12481 ctatgtttat ttattttgtt cttttaaaaa gaacgataca catactgatt tttcggagca
    12541 gagactttct cagcgtttgt aacaactaca gatgggattt cacgcttgaa tggttgataa
    12601 tagtctgatt ggatggttcc ttctatttta taccattcat catttttaac cgttactcct
    12661 tccggcatat gcgtcaacaa accaaagact cctgaatctg ccacacaatg gataatgccg
    12721 aatcggaaca agaagatatc tgtattgcta tcgttcggtg tttggtaaac aaatccttca
    12781 tagctgattt ttttgccaat gaattcgcta gggtaattat aaattagctc cataacttct
    12841 aaatagtttt catctgtgat cttgatagtt tgcttatccc catacttttc tttcaactca
    12901 ttcatttggt ctaagtagtc tgatttgttg aaataaatac tggtatccgg ctttaagtat
    12961 tgtgtctgca tctccggatc ccctactgat tctttactta ctgggaaatt aaatcctttg
    13021 gcttctacga tcgtagtgtc gagactaact gttggaaaca acgtccccac gattactggc
    13081 aaagctagca gtacataagc gattccacgt tgataaggtt ttgacaaccc atggtcatga
    13141 tcgtgctcgt gtgccttttc ttctgctttt ccgtttttga cccacaaata cagctgaact
    13201 aaagccaaaa gagcagataa aatcattgaa agaatagcta agtagcgata atggacattg
    13261 atatattgat cgagtttgcc agaaacttgc aagtacatca tcaattcgaa atacccagat
    13321 aaaatcaaaa accgcagcat attttccctc ctaaataaat aatgtgaatc caataacgct
    13381 aagggcaatc agtccgatca gcgataaaat aaagcgtcct gtaaaatatc gtttcatcat
    13441 cagtagattt ttgatatcga ccattgggcc aaagaccaaa aaggcagcta caggtgctgt
    13501 gccgaacaga cttaacaaag aagatcctat aaacgcatct gcttctgagc aaagagacat
    13561 cgtaaaggcc aataacagca tgatgataat ggctaaaatc tttgttgagc cgagcgttag
    13621 cataattcta gttggtaaat aagtctgcat cgcagctgcg attaatccgc caatgatcaa
    13681 ataacgacct gtatcaaaaa attcgtcgat tgaatgtgtc aacacatgcc cagtttgatg
    13741 gatcagctga ttttttggtt cattcttctc actttgttct tcttcatgga catgatgatg
    13801 gtgattttct gctactttag acgtgatttt ttctttcaat acagcgtctt tttgaaaata
    13861 ggcaagccag acaccaatca caagggcaac aaaaaagctg cctatcaccc gccagcttgc
    13921 catctgccaa gaattgccaa atgcgataaa agtggaaaaa atcacgattg gattgatgat
    13981 cggagcagtc agcataaaag caaacgctgt gtgaactggt acgccttttt taacaaattg
    14041 atgaacgatc ggtacgatgc cgcattcaca tgaaggaaag aaaaatccta agatcgaacc
    14101 agtaaaaata gagaagatac gattttcagg aagccatctc ttcacacgtt ctggggtcaa
    14161 aaatacttgt aaggcgcctg agataagaca gcctaataat acgaaaggta atgcttcaat
    14221 aacgatcgat aagaaaatcg tactcatctg caaaaccgaa tttggaataa aagaaaacat
    14281 gagtttcctc ctttttattt ctagttcatt cgctttgcaa atatacgctt ttattcaaaa
    14341 aaaacaagtt gctctgtaaa tttttacaca actcttattt tttaccaaag cacttcaatt
    14401 gactttttct gttattccca ttaaattaag gtctcataca tatcacttct atcataaaag
    14461 ggagaataaa aatgaaacaa accactaact tgactgaagt tcaagacata ctgcaacagt
    14521 catccgttgc cgtcatttat ctttcgatgc ctaattgcag tgtttgtcac gctgttcgtc
    14581 cacgactaga ggaacttctc acacattatg atattccggc acttcatttg gatgcatttg
    14641 aaacaccaga agtagctagt aaatttgaag tgctgactgc gccagttgtc ctgatttttc
    14701 atcaaggaaa agaagtcttt cggcaagcac ggttcatcga ctttaaaaaa atccgttatc
    14761 tactagatga actgacagca gaagatgatt ccctttctta tgaagaaatc ttccgaacaa
    14821 aataatcgtt gtccaaacag aaaaaagcga ttgaacaagt gaaagttttg ccttcatttg
    14881 ttcaatcgct ttttattttt attctgctgt attttcggaa tgcgcatttg cgtcagaatg
    14941 caagaaatag atcaaggttt gcaattcatt cgtcaaatca acattttgga tcaatacatc
    15001 tgacggagca ttcaatcgag cagcggtaaa gttcaagatt cctttgattc ctgcttccgt
    15061 taactgattg actacttctt gtgctctttc agcgggtatc gttaaaattg ctacttcgat
    15121 ttgttggatc ttgatttgtt ctgacatatc ttccattgga taaacgggga taccgtctac
    15181 gatgcgccca acgatttcct cattcacatc aaaagcacaa ctgatacgta tgctattact
    15241 ttgatggaat ttgtatttta gtaaagcact tcccaagttc cctacaccga tcagcgcaac
    15301 atttgtcaat tgatcgtcgt ttaatgtctt tgcaaaaaag tgcataagat cttctacatc
    15361 ataaccatac ccacgttttc ctaattcgcc aaaataagaa aaatctcgac ggatcgttgc
    15421 actatctact tgaacggctt cacttaattc agttgaagac acttttttct ttccagcatt
    15481 atttaaaatc cttaaatagc gataatacaa aggcagtctt ttagctgtcg cctttggaat
    15541 aatatgatct ttcacgaaat gacctccacg tattgtctaa ttacatcttt gatttctcca
    15601 tcatagcagt atttatagga aaaaatcaat tccattgctc agatattgtg aaattttatt
    15661 ctttattcat ttatttatca tttctgcaaa tctcgcagta taatggaatt tatggtagac
    15721 tactaattga aaaatagttt tttatttgag gagaattcac aaagtagaaa agaggattcc
    15781 atgatattat tacaagccaa tcagattgct cgccattttg gtgcagaagt cttatttgaa
    15841 aacatacatt tagaaatcag tacaggcgct cgtgtcgctt tagttggcag aaatggcgct
    15901 ggaaaatcga ctttattaaa gatcattgct ggaattgaag cacctgatga aggaaagatc
    15961 gctaaaaata aaacagcgac tctcggatac ctcgctcagg acacaggact tgattccaat
    16021 gaaacagttt ggaacgagat gctgaaagct tttgaacaag ttagacaaat ggaagagcgg
    16081 atgcgcgagc tagagatttt cattagcgaa ggtacgccag acacacctgc ttatagttct
    16141 tatttaaaag aatacgaccg gctgcaacac gatttttcag atcgaaacgg ctatggttat
    16201 gaaaatgaaa ttcgttccgt attgcatggg tttaaattcg attcttcatt ttatgatcag
    16261 aaaatcgata ctttatcagg cggacagcgc acacgtttag ctttagctcg catgcttttg
    16321 caacaccctg acattttgat tctagacgaa ccaacgaacc atttagatat cgagacactt
    16381 tcctggcttg agaattatct gcaaagctat actggtgcat tattgattgt ttcccatgac
    16441 cgttattttt tagataaagt agtcaatgaa gtctatgaat taagcagaag aaaaatgcgc
    16501 cattacaaag gtaactattc gaaatatcta gatttgaaag cagaacagtt agcaagtgaa
    16561 tggaaggctt atgaaaagca gcaaacagaa atccataaat tagaagactt cgttgctcgg
    16621 aaccttgttc gcgcctctac cacaaaacga gcgcaaagcc gcagaaagac attagaaaaa
    16681 atggaccggc tggatcgtcc tcaaggggat gaaaaacaag caaactttct attcagtata
    16741 gaaaagcctt ctggaaatgt agtcttgcaa atcgaagatg ccgctatcgg atatgataat
    16801 gtcaccttat ctgaaccaat caatctagat atccgtcgtc aagaagcgat tgctctagta
    16861 ggtccgaatg gtatcgggaa atcgacgttg ctgaaatcaa tcattcacca gatccctttt
    16921 atccgtggaa aagaaacgct agggacaaat gtcaccatcg gctattacga tcaaggtcaa
    16981 gctgatctgc atacaaacaa gacgatccta gcagaattgt gggatgagca tcctaccact
    17041 ccagaaaaag agatccgaag tgctttaggt gctttcttat tttctggcga agatgtagaa
    17101 aaaccaatcc ctctgctaag tggcggtgaa aaagcacggg ttgctttagc caagttagcg
    17161 atgaacaaag aaaatttttt gattttggat gaaccaacaa accatttaga tattgacaac
    17221 aaagaagtat tagaaaatgc attgatcgat tatgacggca cactgctttt tgtttcccat
    17281 gaccgatatt tcatcaatcg gatcgcgaca aaagtcgtcg aactctctga aaatggcagc
    17341 aaagtctatc taggagacta tgattattat ttagagaaaa agcaggaaga agaagaaatc
    17401 gccgaattgt tggcacaaga tgagccagaa tctgctcctg ctcccacgaa caaatctgat
    17461 tattaccaaa gcaaagaaca gcaaaagctt atccgtagcc ttcaacgaaa aattactcag
    17521 gttgaagaag aaatggcgcg gatcgatgaa tggatcgatc agttggaaca agaaatggtc
    17581 gcgccagaaa acctggaaga tcacgtaaaa ctcaatgagc tgaaccaaga tttagaagct
    17641 gctagacaag atcaagaaac aaaattgacg gaatgggaag aactaagctt ggaattagaa
    17701 gaatatgaaa attaacgaaa aaaccaaaac agaaaccatt catgctgttt tggtttttct
    17761 ttttttattt tatcaaacaa aaattccata tttacctttt tcaccaataa gaagaccaat
    17821 tactagtcat tctcactaaa gcttctaaat aatagtaatc accccaaata caaggtgtat
    17881 ttaccccatt atttttgggc ttattataaa cagactgtgt taaaaagcca tcttcttctt
    17941 ccgttgtagc atatctttct ttcaattgtc gcataatttt ccaaacagca gactggtata
    18001 agttcttttc tgttttgtct aatagacctg attctattaa ttctaataat ccacaaacca
    18061 tgatcaccat actagatgta tctttttctt ctctgctaga atcatcaaag atcaaatccc
    18121 aataacaaat ggtatcttct ggcaaccgat tcataaaata attggctaat attttgctta
    18181 aatcaaaata tttttgttct ttcaaataac gataacttaa tgcaaaaccg taaatccccc
    18241 atgcttggcc tctagcccaa caggaattat cactataacc ttgatgcgta cttccatatc
    18301 ttggttttcc atctttgaca tccatataaa atgtatgata agttgaacca tcttctctta
    18361 ctaaataatc tgctgcattt tgaatatgag cctgagcagc ttttttatat ttttgatttc
    18421 cagtttcttc actcgcccaa tacaataatg gaagattcat gcaacaatcc atgatcattc
    18481 taccttgttg tgaaggatca ctaggatctc cccaagcttg tataactcct gccttctccc
    18541 aaaaacgctg aagtaatgtt tctgcagcat caattgaagc ttccttcatt tttcgatttc
    18601 ccgttatttt ataatctgct acggttgata aagaatacaa aaaaccaaga tcgtgatgat
    18661 tagtgataat ttgacagtca atcctgtgga taaaatctat atctgctttt tcagctgttt
    18721 gttgaaataa aggatcaccc gtcttctcaa ataacaacca attaattcct gtccaaaatc
    18781 cttctgtcca accaatattg tctcttaatg gataacgtcc ttttatagga cactcgcttg
    18841 ggaattgata ctgactgtta ctgatacgtt tgattaacct ctccgtgtgt ctgcgacaac
    18901 gctcgatctc attattccat tctttttcca ttaattcttt ataacattca tttatccatt
    18961 tttctggatg tattatctct tcaaacatca ctttatcaag catttcccca ccagccttta
    19021 gcataatttt agtctttttt tattgttttt attttggata gttagcccgg ttgtcccatc
    19081 aaaatcaatt ttgggacgat tgttccatac ttctaaacta taatcccgat cttgatgagc
    19141 aaccactcct gttccgagcc aatgggttcc ttttccaaat gtaccctcta atccaggaat
    19201 aaaagtgttt tcccatgtca tcaagtttgt attgggcaaa cccataatag ctgtggattt
    19261 tcgtttaata gtatcgtcac ttaaacagat aatacctgaa aagccagctt cactcaccct
    19321 atagttttcc ttgtcttctt ctatgattat tccttctttc tcaggagaac attcaatagc
    19381 aaaccctgtc tcatatagaa catattctgt atctaattct actttgtgta cgcgaatctg
    19441 ccagccttca aaaggaataa gccaagttct gatttttgcc tgtaaagtag gttcccatgt
    19501 agaggcaagt acctctttct tacatacaat gtctcgtaca ttatttcgaa cgatgaactg
    19561 tccataggtt ttgatgctct cattcttaaa actggtcgtg atatatgtgt ccgctcgctg
    19621 aatccctagc attgaatcca ttgccatttc tgctttcaat tgattcgctc gcggtatcga
    19681 aaaaccaaat tgactagaat aagcaaattt taaatatttt tcattggtca atgtatggaa
    19741 atttggccct aattgtcccg cattcaaaaa aaatgtatgt ccattatcat gttgtatgag
    19801 caaattggct tctgaaagaa gtttagttcc ttcacgaata ggcataggca tttctttagc
    19861 cgtccaatac tcatggtctt caggtagcgc caacaataaa aaaatcttat tcagccataa
    19921 tggagataac gtactattat agggttcagt caatgtcaat tgagggtagg tataaccaat
    19981 attcaggata cctttttcat caaatatttc tttttgcatc caccatctta tattccgatt
    20041 gactaacccc ttgatttcac ctaatttaaa aggcaaaaga tcggcccaca acatagctga
    20101 ccaaaagctt gaaactgcaa aacgataaat catgcttcga ccaaaaggca catttgcacc
    20161 atcttccgca aaaaaatgaa tatagtctct agaaaaatca atagctcggt tcttatatat
    20221 ctggctaatg ggcttttctg gttctagtac gctataaatc aaaccataat aatgaaatgc
    20281 aaaaggatta taataatctt ggcgacctct tgaactgtct cgataccagc cattttgaag
    20341 ataacaattt tctatattat caaatgcttc tttcagtgct gattctttaa ctggataacc
    20401 aaatttttgg ataattgttc cgacaattat cttaaaaaat tgccaattac catctgcaca
    20461 ttcatattca aaaatttgcg agaaccaatg aataatctgg cttttttctc ctgtatctaa
    20521 ttttttccat aataattgtt catgatgata taacgctaat aacattgcgg gcatttctac
    20581 catacgctgg tctctttcat gtatttctcc ccaataatcg ggatgggaag gatctgttcc
    20641 agcttttatt cctgatagaa ttaatttcaa ccatcgttca tctaattggt caattgcggg
    20701 ccccgctccc cataaaaccc gagagaatcc ttccattcct gcaattttat ttccatatcc
    20761 taccccttga tgtatataat caatttgtgc gccacttgct cgataaaacg gctggagtgg
    20821 ttgatttatc tttttaaata agtcaaagta atcctgtctg gtccttaata gtggtactgg
    20881 atgtttcatt gtattttctc ctctttttac taccaaatag ctaattccga ctgttctaat
    20941 cgaagtaagc cttcaataaa aaaataatca gaatagatca gtggcacatt ataagtcagt
    21001 tctctatggt atgcttctgc tccgcctcca atgatcccat cttcatccat attccaattt
    21061 gcatagtgct tttctgtctt ttggagtata ttgatagcag cttcatgata catttttgat
    21121 cgtacagagg aaacatatcc tgctaattcc agaagaccgc atgcagcgca tactccagca
    21181 ctggtatcaa tattcgaatc ttttacagca aaatcaatga gaggaatata accagttttt
    21241 tcgattttct gaataaaatt tactgctatc ttttctgcta tagctagata gtacggattt
    21301 tttgtgtaac gataacttaa cgcgaatcca tataaagccc atgcatttcc tctgctccaa
    21361 caagaattct cattgtatcc ttgcccgcca agtaaccgaa tatatttccc tgattctgca
    21421 tcaaattctg cgatatgccc ggttgatcca tctttcctca ctagatactt agctgttgta
    21481 tctgcatgct gccgagcaat tttagagaac ctcggatcac cagtttccct cgaagcccaa
    21541 tacagtaatg gtaaattcat catactatca ataatcatcc aaccaggttt atggtcattc
    21601 catgctacta aatagttccc tgaaatatta tagcgtccag caagtaccgt agctgcatgt
    21661 aaccctagtt gtcgactatg tttgttttga gactgttgat aatgtgcaat agccgatggt
    21721 aagaataaaa aacctacatc atgatgaacg tctgaaaaat ggtacagggc agattctaat
    21781 aattgttctt gttgtattgc tgcctctttg aacttttctc gttttgtctt gtgaaagagc
    21841 tgccataaaa taccactcca aaaaccattg gtccaccagt cgattcctct gtcctttatt
    21901 acgtctgtat attttccgtt gtaagaaata tatggaattt tattccccat tctgtctaat
    21961 tccgcatcta tcttttcaga agctacattc aaaatttttc ttgaccattc cttcgtctgt
    22021 tcattcatgg atatcccgcc attcttttaa tttttatgaa tgtggagttg ctcctagaac
    22081 gaactagatg gttaacattc gttatttttt ttacttattt gcagctccaa tgtcattctc
    22141 cttaaattta gactgcgccc acacataaat caagaccatt gggatcactg aagttgctaa
    22201 aattagcata attgcgccat aattaattgg ctcacctgta ctagaaaccg tcatattttt
    22261 gataattaag ggaaccgtat atttatcttt atctgaaagc atgactaatg gaaatagata
    22321 ttgattccaa cttcccataa agataagtaa accactagta ataatcgtag gtgataaaat
    22381 cggtacagcg attttcgtaa aaatcaccca ctcattggca ccatcgattc tggcagcctc
    22441 catcagtgct gtaggaaatt gactgctata ttgtcgcatc ataaacactg aagttgtact
    22501 ggcaatcgaa gggatgatca cacctgcata agtattcgat aatcctaaac gactcataat
    22561 gtaaaataaa ggaatcaatg tggtaaaaaa aggcaccatc ctagatagca taactgtatt
    22621 gaacaacagt ttattcccca taaaacgata ctttgctaat gcataacccg ccattgtaga
    22681 actggctgta gctgaaactg tactgattac agcaataaca atcgaattcc aaataatcaa
    22741 gggataatta tatctcgcca tgatggcttg ccagtttttt aatagcatat ccccaaactt
    22801 gaaattgatt ccgccactta aaatttcttg attactttgc gttgaagcta caatcatata
    22861 taaatatggc atcaaaaata ttaaggcacc aaacacaata atgacgtacg taaaaattct
    22921 gctttgtatc ttttgtttag tcatttttat cacctccgaa tttaaattga atagccgata
    22981 atataacaga tacaaacacc atcgtccagg caatagcaga ggcttttcca aaatcaacca
    23041 tttcaaaact tgttttatat aaattgactc ctacgaccaa agctgaattt tctggtccat
    23101 tggaagtccc aaagaatata tttgggatat tgaaattacc caagccattg atagtggcta
    23161 aaactgtggc cattaaaatg attggcttta gcatggggat cgttaataaa aagaattgcc
    23221 gaaatttcga tgctccatct atttcagcac tttcgtatat ctctttagaa atcccttgaa
    23281 gaccagctaa aaataaaata gtgttatatc ctacactaag ccaaatcatc gtgatgatca
    23341 ttgatattcg tatccaaaaa ggatttgtta accactgtac accgttaatt cctagcgcat
    23401 tcaaaaatcc attgaataac ccagtcggat tgaaaaaagt catgaatacg gaagctacag
    23461 ccaccgttga tgtaatggtt ggaatataat agacagttct aaaaaatcct tttcctttta
    23521 actgtgctga attcaataaa acagcaaagt aaatagctaa tagcatcgtt attggaattg
    23581 atcctgccat gataatcaaa acattcgtgt aagatttaat aaacaatgga tctcggaaga
    23641 tagctagata attgtcaaat ccaacaaatt caaatgagta gccaattttc ataaaactaa
    23701 aagcaaacga gataatgatg ggaatcaaaa tcgtcacaat aaagaaaata acaaaaggtg
    23761 tgaccaatcc ataagcactt tttttatgag acgtatctgt tgcttttttc ttgctgttct
    23821 ttattgtctt gcttggtaac gaagattgca tcatcgttaa gtcctcctaa tattttttaa
    23881 tcaccagtta attttacgcc gtacttatga gcaaaatttt ctgcttcttt tagatatgaa
    23941 ttttcaaaat cacctgtttg ccaatagtta tatgcagcgg tagtcaaata agacgtagca
    24001 tctgaataag tggctggtaa aacagtattt gatgtatttt cattgatttt attcaatagt
    24061 tcatagtatt tttgtcctcc ttagtagtca aactttttct cagctgcttc tgtttgatag
    24121 gccaatgagt tagatgtagc cacgcccagc tccagtgcgt tggctaagca ttcttcatct
    24181 gtcagcataa atgtaagaaa ttgttgtgcc acttgtggat ttttggcatc tttagggaca
    24241 taaaaacttg atcctcctga tactgcacct tttcctggat tttcttttga aaaaggaatc
    24301 agtggagcca tgcgccattt gtcagatgca tcaggaaaat tcaaagacat attcgtagca
    24361 taccagccgc cagcaacaaa cattgcagat tcttgaaatg ctttctcagc atcttgtgca
    24421 ccgtagaaat gtacaatatc tgagtcgatc atttctttga ttaactttgc agcatgtttc
    24481 gcttctttag tattcagacg gatatttcct tcttcatcaa gcaaagattg attctgctgg
    24541 gctagcatgt tgataaacaa ttcttggtcc ccagattctg gcaaggcaat tccaaaacta
    24601 ccagtttttt cttttaatgc ttttgccacc tggatatatt cttcccaaga actgatttct
    24661 tcaaaatcta cacctatttc agcaaatttt tttggttgat aataacaaag tgctggggta
    24721 aaatcactag cccaaggaat aatcgtttca ttactcgttt gttgacgcaa aatattcaat
    24781 ttttgatcat aaaactgatc gccatatttg tcataaaatc catattcatc agcactataa
    24841 aaagcatctt gaaatttttc cagcacacct gctgctgaag tgtctgccat ggagataata
    24901 tccggcatat cttcgtgtgt taccaatttt ggggtgatca tttgtactgt tgctgttccc
    24961 gaagctacat tcacaatttt taagtcaata tttgctccag ttttgcggtt atagattttt
    25021 gcagcatttt caacatagtt tgtcagtttg ccgtttgcga catatacttc taatgtagtg
    25081 gcttttttta tcattggatc tgcgatgttt gctgttactt cttcgttagt ttttccacat
    25141 gcacttaagc tgaataatag ggtaatgttt agcaaagcta tcaccaattt gtatcttttt
    25201 ttcatgtcta tcccttcttt cttttcaagt tcttatataa aacgctttca cttatgtata
    25261 ttaacggaat tagtaacaca aatatttata taaaaaaata ttttacttgt cgttttggct
    25321 tttcattttt gttataatag tcattaatta taaatagaaa gctttttata taaaaagaga
    25381 aaggaaagtg gttcttttgt taacaaacaa ccaatcctcc aatcttgtca aaaaaacact
    25441 aacctattcc atagataccc atcttcattt atctgctgct ccctattttc gactactaat
    25501 aaatgaaagc gctaatttat atgctgaatt tgcacataaa tctatagaac tagataatcc
    25561 ttccctttta ttcattgata aacagcaaga agtccaaatc ttttctactc aaaaggaaac
    25621 acaaactttt atcattatcc agttttattt tgatgagcaa ttattagcac atattacggg
    25681 acaatctttt tctatagatc aagaaataac atctatcatt acttttctga aaaatgaaca
    25741 gttcaaaatt gattatctaa aacatagtaa gccagctatt tcctatgatc aggaaatcaa
    25801 ttcttttttc atactatgcc aacagatgag cattcatttg ctttccttat tagttactta
    25861 ttgtctgcaa aaaattcaat tgtcttcctt accaaggcat tatcaacagg aacttgcttt
    25921 attgacaata ccttcaaatg agaaagtcat tcctaaaaaa aagcatattc tttattcaga
    25981 tgaattagtt gatccaatca tacgatattt agaagaacat ctttcagaaa attttttgct
    26041 tgaacaatta gcccaaattt tttttatcag tccagccagc ttaaaaaaac attttagaaa
    26101 agtgaatgga aaaagtgtta ttagctattt taaagaacta aaaatggaaa aagcaaaacg
    26161 tctcgtgcta gaaaatgaat taacctatac agaaattgca gatatattag gatttcattc
    26221 gatccatcat ttttcttcag cttttaaaaa atatacaggg ttatcccctt caaagtatta
    26281 tctatcctta aaatagaaaa aaatttttag gttttatcca caaattattt ctctatattt
    26341 tctgtctatt caaaataaac aataattttc cggcacaatt atttgctgtt ttttaccata
    26401 acatagtacg atcaacgtag aaaaggagat gtttttatga aagttgttgt cattggcggt
    26461 gtagctggcg gtccttcatt tgccactcgt ttccgtcgat tgaatgaagc gcacgaaatc
    26521 attatctatg aacgcggaga aaatatttct tatgcaagtt gtgctttgcc ttattattta
    26581 ggaggtgtga tcactgaccg tgactcgctg atcgaacgta caccagaaat attgaaaaca
    26641 aaaaacaaca tcgatgtctt tactaaacac gaagtaacag caatcgatcc ttctactaag
    26701 cgattaacag ttaaagacct atccacaaat gaagaaataa aaacagatta cgataagttg
    26761 atcatctctt ctggtgctag accagattat ccggatattc ccggagtttt tgaagcagaa
    26821 aacggctttg tcctccgtag tgtgacggat gcggatcgaa tcaaatcgtt ccttgaagaa
    26881 aaaaatccac aacatgtcgt cattcttggt gcaggtgtta tgggtctgga attagctgag
    26941 aatttcaagc atcgcggctt agacgtgact ttaatcgatc aattgccaca agtcgctttc
    27001 ccttatgatc cagaaattgc taatttagtt tatgacaaat tgctgaaaga aggattagcc
    27061 gttcatttag aaacaagagt tactgagatc cgtgataaag gtcgagaaat agtattatca
    27121 gatggctccg tcctttctgc tgatatgcta atttttgctg ttggtgtttc tccgaagaat
    27181 gaagtggtga aagcaaccgg catacaatta tcagatacag gtcagatcat tgttgatgac
    27241 cagttacaaa ccaatctgcc ggacatctat gcgattggcg atattatcga aacgactagt
    27301 gtagtgactg gtcagccgat ccaaagtatg ctttccagtg cggccaatcg tcaaggacat
    27361 atgctggcag atattttaaa tggtacgcct atgcgctatc gcggatatat tggtgcaggt
    27421 gtcgcaaaaa tctttgatca tacagcaagt tatgcgggaa tgacagaaca tgaattaaaa
    27481 gcatcaggca taacaaatta taaaactgtt tttatcactc cctttgacca tgcctatttc
    27541 tatccagaag ctacaagatt aaatctaaag ctgatttttg atgcagatag cggtcgtatt
    27601 ttaggtggac aagcatttgg agaaaaaggt gtcgataaac ggatgggaga actttctgta
    27661 gcaatcaccg gaaacttgac agtctttgat ttgcctgatt tggagttgcc ttactctcca
    27721 ccgtattcta ctacccgtga cccgttgaat atagctggtt atgtcgcaat caatcaaatg
    27781 acgaatatcg tagaaacgat caaagcaagt gatatacccg aaaacgattt gaaagaagcg
    27841 ttctttttag atatacgtga acctaataaa gcaccttctg gcagtatctc ggcaacaaaa
    27901 aatattccaa tgaatgagtt acgagatcga atcaatgaaa tcccaaaaga taaaaaagtt
    27961 tacattactt tcagaagagg attgaatact tatacttctg cccgaatctt ggcaggtttg
    28021 ggtatcaaag cgattttgat tgaagaataa aaaaacgacc gcggtgggta gccgcggtct
    28081 aggagttatt tttacttgag gagtaaaaat gaaaaagtat atagggttgt tggttggtat
    28141 gtatatagaa tagaagataa atgtgaagaa attgtgcatt atttcttcac atttattagg
    28201 ttatagttta agaaagttta aacattgcgc aatttaatta ttttagctgt ttcttttcat
    28261 aaaaaaacat gttgtgactc tgagacaaat catagtccat agtgatgtct ctagagtaac
    28321 tacgcctaat attacgaggc atcatattaa tctatcagca ctagtaccta aactagcatc
    28381 cctttcgaat attttttctt atataataaa gtttgctttc actcctctaa tctcaccaaa
    28441 tcgactggct tgcgttgtgt gatactagga actgattggt ttagaacgac ttttctattg
    28501 taatcatatt tttcgccatc ctcgttgtct tctaatcctt caatgaatga tccctaatgt
    28561 gtgtattaaa taatttaatt tttttgttcc tatttattta aca
//
LOCUS       DAPBAF010000037        28413 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.037, whole genome shotgun sequence.
ACCESSION   DAPBAF010000037 DAPBAF010000000
VERSION     DAPBAF010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 28413)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28413)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28413
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.037"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            8..81
                     /locus_tag="RD451_001931"
     tRNA            8..81
                     /locus_tag="RD451_001931"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:42..44,aa:Pro,seq:tgg)
     gene            101..173
                     /locus_tag="RD451_001932"
     tRNA            101..173
                     /locus_tag="RD451_001932"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:134..136,aa:Ala,seq:tgc)
     gene            201..274
                     /locus_tag="RD451_001933"
     tRNA            201..274
                     /locus_tag="RD451_001933"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:235..237,aa:Met,seq:cat)
     gene            288..361
                     /locus_tag="RD451_001934"
     tRNA            288..361
                     /locus_tag="RD451_001934"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:322..324,aa:Ile,seq:cat)
     gene            385..474
                     /locus_tag="RD451_001935"
     tRNA            385..474
                     /locus_tag="RD451_001935"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:421..423,aa:Ser,seq:tga)
     gene            487..560
                     /locus_tag="RD451_001936"
     tRNA            487..560
                     /locus_tag="RD451_001936"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:521..523,aa:Met,seq:cat)
     gene            579..654
                     /locus_tag="RD451_001937"
     tRNA            579..654
                     /locus_tag="RD451_001937"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:612..614,aa:Asp,seq:gtc)
     gene            656..726
                     /locus_tag="RD451_001938"
     tRNA            656..726
                     /locus_tag="RD451_001938"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:688..690,aa:Gly,seq:tcc)
     gene            740..813
                     /locus_tag="RD451_001939"
     tRNA            740..813
                     /locus_tag="RD451_001939"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:774..776,aa:Ile,seq:gat)
     gene            838..925
                     /locus_tag="RD451_001940"
     tRNA            838..925
                     /locus_tag="RD451_001940"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:872..874,aa:Ser,seq:gct)
     gene            947..1018
                     /locus_tag="RD451_001941"
     tRNA            947..1018
                     /locus_tag="RD451_001941"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:980..982,aa:Glu,seq:ttc)
     gene            1041..1130
                     /locus_tag="RD451_001942"
     tRNA            1041..1130
                     /locus_tag="RD451_001942"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1077..1079,aa:Ser,seq:tga)
     gene            1143..1216
                     /locus_tag="RD451_001943"
     tRNA            1143..1216
                     /locus_tag="RD451_001943"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1177..1179,aa:Met,seq:cat)
     gene            1235..1307
                     /locus_tag="RD451_001944"
     tRNA            1235..1307
                     /locus_tag="RD451_001944"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1268..1270,aa:Asp,seq:gtc)
     gene            1311..1383
                     /locus_tag="RD451_001945"
     tRNA            1311..1383
                     /locus_tag="RD451_001945"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1344..1346,aa:Phe,seq:gaa)
     gene            1388..1458
                     /locus_tag="RD451_001946"
     tRNA            1388..1458
                     /locus_tag="RD451_001946"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1420..1422,aa:Gly,seq:tcc)
     gene            1471..1544
                     /locus_tag="RD451_001947"
     tRNA            1471..1544
                     /locus_tag="RD451_001947"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1505..1507,aa:Ile,seq:gat)
     gene            1556..1627
                     /locus_tag="RD451_001948"
     tRNA            1556..1627
                     /locus_tag="RD451_001948"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1589..1591,aa:Glu,seq:ttc)
     regulatory      1816..1895
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01767"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitches modulate the expression of
                     downstream genes in response to levels of
                     S-adenosylmethionine. SMK box riboswitch (aka SAM-III)
                     shares no known similarity to SAM-I and SAM-II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF01767"
     gene            1893..3086
                     /locus_tag="RD451_001949"
     CDS             1893..3086
                     /locus_tag="RD451_001949"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HDT7567187.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            3216..4688
                     /locus_tag="RD451_001950"
     CDS             3216..4688
                     /locus_tag="RD451_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDT7567188.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            4771..5559
                     /locus_tag="RD451_001951"
     CDS             4771..5559
                     /locus_tag="RD451_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HDT7567189.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(5626..6294)
                     /locus_tag="RD451_001952"
     CDS             complement(5626..6294)
                     /locus_tag="RD451_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HDT7567190.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQIMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            6409..8121
                     /locus_tag="RD451_001953"
     CDS             6409..8121
                     /locus_tag="RD451_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7567191.1"
                     /translation="MKLILRHAKKYKVAVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            8124..9893
                     /locus_tag="RD451_001954"
     CDS             8124..9893
                     /locus_tag="RD451_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010762530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7567192.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENCKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFE"
     gene            complement(10098..10664)
                     /locus_tag="RD451_001955"
     CDS             complement(10098..10664)
                     /locus_tag="RD451_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HDT7567193.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(10664..11620)
                     /locus_tag="RD451_001956"
     CDS             complement(10664..11620)
                     /locus_tag="RD451_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HDT7567194.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(11620..12276)
                     /locus_tag="RD451_001957"
     CDS             complement(11620..12276)
                     /locus_tag="RD451_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HDT7567195.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            12646..14664
                     /locus_tag="RD451_001958"
     CDS             12646..14664
                     /locus_tag="RD451_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HDT7567196.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     misc_binding    14734..14940
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            15091..17505
                     /locus_tag="RD451_001959"
     CDS             15091..17505
                     /locus_tag="RD451_001959"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HDT7567197.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            17853..19406
                     /locus_tag="RD451_001960"
     CDS             17853..19406
                     /locus_tag="RD451_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HDT7567198.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(19787..21571)
                     /locus_tag="RD451_001961"
     CDS             complement(19787..21571)
                     /locus_tag="RD451_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7567199.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTDINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNFAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(21586..23307)
                     /locus_tag="RD451_001962"
     CDS             complement(21586..23307)
                     /locus_tag="RD451_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7567200.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLQIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            23407..24168
                     /locus_tag="RD451_001963"
     CDS             23407..24168
                     /locus_tag="RD451_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDT7567201.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
     gene            25135..25403
                     /locus_tag="RD451_001964"
                     /pseudo
     CDS             25135..25403
                     /locus_tag="RD451_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
     gene            26075..>28413
                     /locus_tag="RD451_001965"
     CDS             26075..>28413
                     /locus_tag="RD451_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567202.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTSNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGET
                     LQTGLTTGEDGKLAIDGLAPGAYQLVETQAPIGYELDATP"
BASE COUNT         8966 a         5077 c         6015 g         8355 t
ORIGIN      
        1 aattaaacgg gaagtagctc agcttggtag agcacttggt ttgggaccaa ggggtcgcag
       61 gttcgaatcc tgtcttcccg ataattataa atttaaacac ggggccttag ctcagctggg
      121 agagcgcctg ctttgcacgc aggaggtcag cggttcgatc ccgctaggct ccatttcatt
      181 taaataatga atatcttttt cgcggtgtag ctcagctggc tagagcgtcc ggttcatacc
      241 cgggaggtcg ggggttcgat cccctccgcc gcgattttta agagcctgga cctttagctc
      301 agttggttag agcagacggc tcataaccgt ccggtcgtag gttcgagtcc tacaaggtcc
      361 attgtggcgt tgtaagtttc atatggagga ttacccaagt ccggctgaag ggaacggtct
      421 tgaaaaccgt caggcgggta aaaccgtgca agggttcgaa tcccttatcc tcctttttca
      481 tattatcgcg ggatggagca gtctggtagc tcgtcgggct cataacccga aggtcgtagg
      541 ttcaaatcct gctcccgcaa ttaaaaacta aaaacactgg ttccgtggtg taggggttaa
      601 catgcctgcc tgtcacgcag gagatcgcgg gttcgattcc cgtcggaacc gccatgcggg
      661 tgtagtttag tggtaaaacc acagccttcc aagctgttgt cgcgagttcg attctcgtca
      721 cccgctttta gttttttatg ggcctatagc tcagctggtt agagcgcacg cctgataagc
      781 gtgaggtcga tggttcgagt ccatttaggc ccattagtac aaaatcttat tggttttggg
      841 gaagtactca agtggctgaa gaggcgcccc tgctaagggt gtaggtcggg aaaccggcgc
      901 gagggttcaa atccctcctt ctccgtttca atattttgtt ttacctggcc cgttggtcaa
      961 gcggttaaga caccgccctt tcacggcggt aacacgggtt cgaatcccgt acgggtcatt
     1021 aatttaatat agttttacat ggaggattac ccaagtccgg ctgaagggaa cggtcttgaa
     1081 aaccgtcagg cgggtaaaac cgtgcaaggg ttcgaatccc ttatcctcct ttttcatatt
     1141 atcgcgggat ggagcagtct ggtagctcgt cgggctcata acccgaaggt cgtaggttca
     1201 aatcctgctc ccgcaattaa aaactaaaaa cattggttcc gtggtgtagg ggttaacatg
     1261 cctgcctgtc acgcaggaga tcgcgggttc gattcccgtc ggaaccgttt ggctcggtag
     1321 ctcagttggt agagcaatgg attgaagctc catgtgtcgg cagttcgatt ctgtcccgcg
     1381 ccattatgcg ggtgtagttt agtggtaaaa ccacagcctt ccaagctgtt gtcgcgagtt
     1441 cgattctcgt cacccgcttt tagtttttat gggcctatag ctcagctggt tagagcgcac
     1501 gcctgataag cgtgaggtcg atggttcgag tccatttagg cccatttatt ttattggccc
     1561 gttggtcaag cggttaagac accgcccttt cacggcggta acacgggttc gaatcccgta
     1621 cgggtcatgg aagatacttt ttgagtatct ttttcttttt atctgaaaga atgattttaa
     1681 aaagcttagc agagttatct ttatggatga ttgtgctaag cttttttgga cagttctaat
     1741 gtaaaatatt tttatatttt ttaagcaaaa aaatgaaaaa atacgagcag aaaactgttt
     1801 tatctgctat acttggttcg ttgcaagttc ccgaaaggat ccgcaggacg gagatgcctt
     1861 gtaaccgaat ttaactaggg ggaatcatta taatggtaga aagacactta tttacatcag
     1921 aatctgtttc tgaaggacat ccagataaaa ttgctgacca aatcagtgat gcaatcttgg
     1981 atgcaatttt aaaacaagat ccaacagcac gagtagcgtg tgaaacgtct gtaacaactg
     2041 gtcttgtttt agtatttgga gaaatatcta cgacggcata tgtagatatt caaaaagtcg
     2101 tacgggaaac aataaaagaa attggttata cacgtgcaaa attcggattt gatggagata
     2161 cagcagctgt attggttgcg attgatgaac aatctcctga tattgctcaa ggagttgatg
     2221 aagcacttga gatccgggat gaagataaaa aagacgtatt agatgagatt ggtgctggtg
     2281 accaaggttt aatgtttggg tttgctgtag atgaaacacc agaattgatg cctttaccaa
     2341 tcgctttgag tcatcgtctg gtacgacgct tggcagattt gcgtaaatca aatgaattaa
     2401 cgtatttacg tccagatgca aaatctcaag taacggttga atatgatgat caaggacaac
     2461 cggaacgcgt agatacaatc gttatttcaa cacagcatga tgatgcagta gataatgaaa
     2521 caattcgtca tgatgtcatc gaaaaagtag tgaaggaagt tattccagct gaattattag
     2581 atgatcaaac gaaatattat atcaatccga ctggccgatt tgtcattggt ggtcctcaag
     2641 gggatgccgg attaacagga agaaaaatca ttgttgatac gtatggcggt tatgctcgtc
     2701 atggtggcgg tgctttttct ggtaaagatg cgacaaaagt tgaccgttct gccagctatg
     2761 ctgcacgtta tattgctaaa aacattgttg cagcagggct tgctcgcaaa gcagaagtac
     2821 agctagctta tgcgattggt gttgctcaac ctgtttcgat ctcaatcaat actttcggta
     2881 ctggaacggt tccggaagaa gaactgattg ctgcagtgag agaaaacttc gatcttcggc
     2941 cagcaggaat catcgagatg cttgatttgc gtcgtccgat ttacaaacaa acagctgctt
     3001 acggtcattt tggtcgtaca gatgtagatt tgccttggga acatacggac aaagtagatg
     3061 cgttgaaagc aagtttagca aaataagtta tattcagctg gaacgatcgc caagtggtgg
     3121 ttgttccagc tttttttatg gcagttaacc tcttgaaaaa gatagtaatt atttatctat
     3181 ttttagatcc tgtcataatg aaagggagga ataagatgaa aaaagaaaca aatgttactt
     3241 tggtcacagt gagtattttc attgcaacgt tcatgacggc tattgaaggt acaatcgtaa
     3301 caaccgctat gccaacgatt gtcggttcat tacatggaat ggaaatcatg aactgggtat
     3361 tttcgattta tttgctgaca aacgctatgc ttactccgat ttacggaaaa cttgcggata
     3421 aagtgggacg gaaaccaatc tttatttttg ggacattatt gtttattatc ggttcgttat
     3481 tttgcggttt atctcaaagc atgattgggt tgattgctgc tcgtgcgatt caagggatgg
     3541 gtgctggggc aatgatgcca gtagctttga cgatcatcgg cgatctttat tctattgaaa
     3601 agcgagcaaa agttttaggt ttgaatagtt cagcctgggg gattgccagt gtttttggac
     3661 cgcttgcggg aggattcatc gttgaaacga tcagctggca ctggatcttt tttatcaatg
     3721 tgccgatcgg aattctatta attattttga tttggctata tttaaatgaa ccaaaaatca
     3781 tacatgagtc taaaccaatg gatatttttg gtagttttag tttgatggcc atgcttgtct
     3841 cattgctgtt agggttccaa ttattaggag acgaaggaat gagtccgctt gtttctgctt
     3901 tgctgctagg tagtatcgta atgttaggta tttttgtttt tgccgaaaaa agagctaaag
     3961 atcctgtcat catgatgcat ttattcaaaa atccactatt tgttgtggtc aacttggctg
     4021 cagcattggc tagtggtttt ttgatgggaa tcgatgttta tatccctatg tggatgcaag
     4081 gtgtattagg gctgaatgca gcaattggtg ggctggtatt agcaccatta tcactagtct
     4141 ggatggtcgg ttctttcctt gcaagcaagt ggatgactca aatgaaaact cattgggtct
     4201 tgagaattgg actactaatc gcagctattg ggggcgcttg gttgtatctt atgcctttca
     4261 gaagtaacta tttatggttt tttgctatat caacggtcat cggtataggc ttaggtgtga
     4321 ccatgactac ctcgactgtc agtgcacaaa atagtgtatc tcgtgaccag cttggtgtag
     4381 caacttcttt taatacgtta gttcgaacaa ttggtcaaac agtcatggtt tctatttttg
     4441 gtttattgat aaatggggta actaaacgag aacttgcagc agcaaattta acaaatgatg
     4501 cagatatcat gaataaactg gtgaatccac aaacggctaa atatattgat gcggatattt
     4561 tgttaccatt aagaaaaatt ctttatgatg ggttacattc cgtttatcta gttggcttgt
     4621 tactcgtgat cattgctttg gtcttaacgc ttttcgttca tgaaaaaagt ggtaaaataa
     4681 aacagtagtt tcggttaaga tatgtacgta gccgaatcat tcaaatttaa agttattcaa
     4741 aaataacttc ttactaagga aggcgaaaat atggcattta ttcaagcaaa tatttattcg
     4801 aatgtgttag aaatggaagt caatctaaat gtgatactac cgcaaacaac aaaaaaggtg
     4861 attggcacca gttcagagca agagacaacg gatatacctg ttttatattt acttcatgga
     4921 atgggtggca atcatagtgt atgggaaaga cgtacgtcga ttgaacgtta tgtagcaaac
     4981 tacggattag ctgtcatcat gccatctact gatcttggct ggtacacaga tacagtttat
     5041 gacatgaagt attggacatt cattgcagaa gagctacctg agatttgtca tgaattattc
     5101 ccgcaattaa caagaaaaag agaaaaaaca tatgccgctg gattatcgat gggcggatat
     5161 ggcgcgttaa aactaggcct tgcaaaatca gaaaatttcg cagcagtaat ctctctttca
     5221 ggcgctgttt ctgtaggaaa tcgaatggat gatcttttga tggttcgtaa agcatctttt
     5281 tgggaaggga tctttggacc attggatcaa atcgaaggtt caaaaaatga tccgcaatac
     5341 ttattgaaag aactagtaaa aagcggaaaa ccagttccaa gattttatat ggcttgtggg
     5401 gaatctgatt ttctttatca ggcaaatcag gaaatggtat ctgctatgca ggaacaaggc
     5461 ttggcggtca cctttgaaca aggacctggc gatcataact ggatcttctg ggaccaatgg
     5521 attcaacgtg cattggcgtg gctaatggaa gaaaaataaa aaaagagtct taaaaagata
     5581 gctcctatag agatcacaaa catagtgatc tctataggag cttttttact gctcgttttc
     5641 tcttctttta ttttgttggc ataagccttc aatataggtt tgtgcactcg ttagaaagag
     5701 tgctttttca ttcaattctg catgggactg catactttct ttaaatccct ctaattgatt
     5761 ttcaactaca taattacgca taaatagaac tgtttctttc aaaaattcat ttccgtccat
     5821 aattttttgt cgaagctgct gttcatgctg ctgatccatt aactgtccaa tcaataaatt
     5881 gtggagagag gcaatggcct gatgactttg ggtgactgaa aatccttcac gaacaagtaa
     5941 ttggatcatt tgctccaaat gttctaatcg actcggaaaa gcgggcacag tattgatttc
     6001 taattctgcc ccacaaggga aacgtgtata aaggtcatag taattttcca tatactgcag
     6061 caactgttca ttccaaggca aagttggatc tggaagcgct aattcttctt ccattgtttc
     6121 agccattatt tgcaagagct gttgtttgtt tttgaaatac caatataaag caggtgcttg
     6181 aacatgaatt ctgtttgcga tgtttcgcat ggaaagctgc gaaagagctt gtgtttcagc
     6241 caggatatca aaggcggcct gaatgatgat tgcttgagaa agctttattt ccattttatc
     6301 aacctcgtgt attgcattat ctttttaaac atggtaaatt gttagtcggt ctaattttac
     6361 agtgttaaat tagtcctgtc aatttaaaca aaggggtgta atcaacgaat gaaattaatc
     6421 ttacgacatg cgaaaaaata taaagtagct gtttttattt ccttgctgtc cgtagcagtc
     6481 atggttgcag cagcattatg gcaacctaag ttactacagc aagtattgga agctattatt
     6541 acagaagata atgatgaaat gaaaacaatt ggtatttacc tgatcagtct ggctttgcta
     6601 ggattagccg caggtgtaac gaacacgatt ttctctgcaa aagtagctca aggcgtaagt
     6661 gcagatatcc gagaagaagc atttcgaaag atccagacat tttcatttgg aaatatcgaa
     6721 cagttctctg ctggaaatct tgttgttcgt ctaacaaatg atatcacgca aatccaaaat
     6781 ttagtgatga tttctttgca atcacttttt cgaattccat tcttatttat tggtgccttc
     6841 attttagcta tgatcacgat gccgcaatta tggtggatca tcgtagcgct tatcgttacg
     6901 gtatttctga ttacggcact ttcatttaca aggatgggca agcacttcat gatcattcaa
     6961 aaactgattg atcgtgtgaa tagcattgca aaagaaaact tactagggat tcgtgtagtg
     7021 aaatcttttg tacaagaaga aaaccaattg aagtcattca gcaaagtaag tgaggactta
     7081 acaaaacaca acatcatagt cggtacatta ttttctgtga tgatcccgtc cttcatgctg
     7141 gctgccaatt tggctgtggt tggggcgatc ttttttgtga gcgatcttgt taaagatgat
     7201 cctacgttaa ttggtggaat tgcttcattc atgaactact tgatgcagat tatgatggca
     7261 atcattattg gcggaatgat gatgatgatg acttcaagag cagccgtatc gctgaagcgg
     7321 attgcggaaa ttttagatgc tgaaccagat cttacttatt tagacgttcc agaacaagag
     7381 ttgacgggtt ctgtcacttt tgaccatgtt tcttttcgtt atcctggtga ggatacagat
     7441 acgcttaaag atatcagctt ttctatcaaa cctggagaaa tggttggtat cgtcggggcg
     7501 actggtgccg ggaagtcaac actagcacaa ttgatccctc gtctatttga tccgacagaa
     7561 ggcaaagttg aagtaggtgg tgtagatctt cgtcaagtaa atgaaaagag tttaagacaa
     7621 acggtttcct ttgttttgca aaaagcaatt ttattctcag gaacgattgc tcaaaacttg
     7681 cgccaaggga aaaagaatgc aacagaaaaa gagatggaac atgcttcttc tattgctcaa
     7741 gcaaaagaat tcatcgaaaa gttatctgat cgttacgaag caccaataga agaacgtagc
     7801 agtaactttt ctggtggtca aaagcaacgt ttatccatta ctcgtggcgt tatcggtaat
     7861 ccaaagatct tgatcctaga tgacagtacg agtgcactgg atgctcgctc tgaaaagctg
     7921 gtccgagaag cactcgatcg agatttgaag ggaacaacga cgattgtcat cgcacaaaaa
     7981 attgcttctg ttgtcaaagc agaccgcatc ttagtattgg atgaaggcag attagtcggc
     8041 gaaggaaccc atgaggaatt ggtagctgga aaccgtgtct atcaggaaat ctttgaaact
     8101 caaaaaggaa cggaggagta agtatgactg atctaataaa agcaagtaaa tttttctatc
     8161 actatttgaa gcggtacaaa ctctcctttt tctttatctt tatcacagtg atcattgcta
     8221 cctatctaca agtaaaggca cctcaataca tcggggaagc ttttcaagaa ttagctaatt
     8281 acgtaggagg cttgatgcaa ggcgtagacg ataaaagcaa atttgtttct gtaatatgga
     8341 aactcttgct gttttatgta ctagctagtg cagccaactt tatctatagt attttgttca
     8401 cacaagtagt agggaagtca acgaaccgaa tgcgtatcgg tctattcaac aaattggaaa
     8461 aattgacgat ccgtttcttt gattctcatc aagacggtga aattttaagt cgttttacca
     8521 gtgacttaga taatattcaa aatagtttga accaagcttt gcttcaagtc atcacgaatg
     8581 ctgttttact tgtcgggatc ttgatcatga tgttccgcca aaatgtagag ttagcttggg
     8641 ctacaattgc ttccactcca gtagccgttt tgatagctgt cttgattatc cgcaaagcac
     8701 ggaaatatgt ggatcttcag caagatgaag tggggaaact aaatggttat atggatgaaa
     8761 aaatcagcgg acaacgtgtc atcatcacaa atggcttaca agaagaaacg attgaaggat
     8821 tcttagagca taatcaaagt gttcgcgaag caaccttcaa aggacaagct tattctggtc
     8881 tactatttcc gatgatgcaa ggaatgtcac tggtcaatac agcgatagtt atctttttcg
     8941 gcggctggtt agcattaaat ggtgatttgg aacgttcggt ggcattaggc ttagttgtga
     9001 cattcgtcca gtattcacaa caatattacc aaccactgat gcagatttca tctggataca
     9061 gcatgatcca attagcgatt acaggggcaa gacgattgaa tgaaatattt gatgaaaaag
     9121 atgaagtcaa accagaaaac tgtaaagcat ttgatggtgt tgaaaaaggt cttgcgttgc
     9181 agcacgtaga ttttggttat tctccagaaa aactagtctt gaaagatgtc tcgatcaatg
     9241 tggacaaagg agaaatggtt gctcttgttg gtccaacagg atcggggaaa acgacgatca
     9301 tgaatctgct aaaccgtttt tacgatgtca atgatggttc agtagtcatc gatggaatag
     9361 atatccgaga ttatgatctt gatgcattac gtagacatgt aggaatcgtt ttgcaagaat
     9421 ctgtattgtt ctccggaacg atcaaagaca atatcacatt cggcaaaccg gacgcttcag
     9481 atgaagaagt catcaatgca gcaaaacaag cgaatattca tgacttcatc atgacgttag
     9541 aaaaaggtta tgatacagag atatccgaag aaaataactt attcagtaca ggtcaaaagc
     9601 agttgatcag tattgctcga acgatcatca caaatccatc tttattgatt ttggatgaag
     9661 caacaagtaa tgtagacacg gtaacagaag caaggatcca aaaagcaatg gatgaagcaa
     9721 tcaaaggaag aaccagcttt gtgattgctc accggctgaa aacaatcttg aatgcagata
     9781 gaatcgttgt cttgcgtgat ggggaagtca ttgaagaagg cagtcatcac gagttattag
     9841 cagaaaatgg attttatgcg gaactttatc ataatcaatt tgtatttgaa taaagaggtt
     9901 gtgaaaaagc tgtcctgcat caagtaataa gaacagccaa tcaaaaacag cttctcatgt
     9961 ttttgatttg gttggactta ttaccgcaga tataagcttt tgagcaccgt gaataaagag
    10021 gttatgaaat caacgctcta acctgagtat tagagaaaaa aacgcaaaac atatcattta
    10081 tgttttgcgt tttttattta tctttttttc tcaatacaat ataaaatagg cggctggttc
    10141 ttttggttga taaaccgata attcagcaca ttatatgttt cctgtggcag tttggaacaa
    10201 aaagaatcaa ccatatccag ttctttttct ccaccttcat gaccatagta gacgacaagg
    10261 atcaatcgtc cgcgaggcac aagtcgtttc aatatttctt ccatagctgt gcgtgtagtc
    10321 tctggcatag tgatgattgc tttatcactt tttgggagat accctagatt gaaaatccct
    10381 gctttgagat tttgttgttc agctatcact tctcctaacg tttcgtggcc ttgtagaaac
    10441 aatgagacac gttcttctaa ctgacgctgt tctagccttt cacgagtagc atcgattgct
    10501 tgttgctgga tatcaaaact atagacatga ccagtttttc cgatgtgttc tgctagaaaa
    10561 accgtatcgt ggccattgcc catcgttgca tctacgacgt gatcccctgg ttgcaagatt
    10621 tcttgcagta atgtatggct gaaatgcaaa gcagtttgca acatcagacg ctcacctttt
    10681 tccgtacatc atattttcct tggaagctat ctctgcgaag aagttcttca tcaattgcat
    10741 tcaagacttc ccattttttc aagctccaca ttggtccaat caaggaatcc cacggcgcat
    10801 cccctgtcaa acgatggatg atgatctctt ttggtatcat ttccagctgg tcgcaaatga
    10861 cattgacata gtcaggacgg ctcattaatt gaaggcgacc ttcatgatag tcccgcaaca
    10921 ttctcgtttt gcgcatcaga tgcatcaaat ggagcttgat tccttggata tctgaatcta
    10981 aaatggtgcg tctgacattt tctttcatca tttctaaact ttcgcctggt aatccgttga
    11041 tcaaatgcgt acaaacacgg atattatgtt tgcgtaattt agccacgcca tctaaataag
    11101 tttgataatc atgtgctcgg ttgatcagtt ttgaagtttc ttcaaaagtt gtttgcaatc
    11161 caagttctac ccataaatac atccgctcgt tcagttcagc aaggtaatca actacttcat
    11221 ctggcagaca atccggtcgt gtaccgactg ataatcctac gacacctggt aaattgacta
    11281 cttgctcaaa tcgttctttg attatttcaa ctggcgcatg ggtgtttgta aaattttgga
    11341 aataaacgat gtattgttgg acatgaggcc atttttgatg catcatgtcg atttctttct
    11401 ggaattggat tggaagaggg tcttcaggtg caacgatcat gtctcccgaa ccagatacac
    11461 tgcaaaaagt acaaccgcca tgggcaacag tcccatctcg attcggacag tcaaatcctc
    11521 catcgatcgg caccttgaaa attttcccgc caaactcatt tcgtaaagcg taattccaag
    11581 aatgatatct tttatttcct tctgaataag gaaaagtcat taaaagtcct tctttctgta
    11641 agagttatct atttgttttc ttttttctct atacactgga taagtcaggc acagccaaga
    11701 aagactgagt aagtaaccgc cgatgatatc agtaggaaaa tgaacgccca gataaatgcg
    11761 gcttatcccg acacttacta taataaacat catcagcaat tgaagcaatg tgcgtaaggt
    11821 tcttttttga acaaaagctg gaagcagaaa tagtaaagaa ccgtaaagaa tcatactgcc
    11881 tgctgcatgt ccactaggga aactgtaact tgtttcaact actaagtgcg ccaatgaagg
    11941 acgctctcgc atgaaaaata gtttgatcac cgggttgatg attccagcaa ttacaataaa
    12001 tccagaaacg aaccaaaatg tttctgccct ttttttctta taccacatcc ataaagccgc
    12061 acaagcaaat aaaatgatga cggtaagagg attaccgaat ttagtcataa agagttggta
    12121 gctgttcaga tcaggataag aagctctgac aatgcctgta aaccactgat cgaaaccaga
    12181 aagccacgac agatggaact ttacgatcca gcccaaaatg aaaaacagga caagaaagaa
    12241 gctaccagcc acctgaaatg atgttttata tttcatacaa ttcctccttt gaagcaatga
    12301 cttattatag catttttggt ccagcgaaaa aaacggtaaa gagataaaac caatgtatga
    12361 ttcctctttg aataaccaat attcttataa aaaaaataac tgtaatcgga aagacatttt
    12421 ttggtaatgc aaatgaaatg ttagggaaat aaaatcagtg tttttcgaaa tccttttaaa
    12481 caagaacgta gacgtaggaa gaacttgaaa atgaacagaa gttgttcatt acggtaaatt
    12541 acaatatgat tacaaaaaac aacaaagctc ttaaataact tttaataaat attaagagaa
    12601 gttataatta ttaataatag ataaattgaa gttggaggat agaagatgga aaacattgca
    12661 agaaaagaac ggagacgttt agaacagacc aaacgttttc gaaaagcaaa acgaggggca
    12721 gcaatcgtgg gaactgcgat ggtaggctgt tctgtcgctg ccccattagt acagccggtt
    12781 cctgttcaag cggatgaaac acctgttcag ttcggcgcaa gaatcaatac agcggcattt
    12841 atcacagaaa ttgctactta tgctcaacca atcgctcaag ccaacgatct atatgcatca
    12901 gtgatgatcg cacaagcagt tgtagaaagc ggttggggca gtagtgcgtt atctcaagca
    12961 ccttattata atctttttgg gataaaaggc agctatcaag gacaaaccgt ctacatggat
    13021 acgcttgaat ttttaaataa tcaatgggta aataaaaagg agcctttccg acaatatcct
    13081 tcttttgctg aatctttcaa tgacaatgcc tatgtactta gaaatacttc atttggcaac
    13141 ggttattact atgccggtac ttggaagagc aacacgaaat cctatacaga tgcgacagct
    13201 tgtttgacag ggcgttatgc gactgatcct ggttacgcag gcaaattaaa taatatcatc
    13261 gcaacttacg gattgaccca atatgataca ccagctagcg gaaacgcagg cggtggagcg
    13321 actacaggtg gcaataatac tggaagtgca ggtagtactg gcggttcaag caattctggt
    13381 aatacaaact caggttcagc aacttcgacc acttatactg tccaatctgg tgattctgtt
    13441 tggggaatct caaataaatt cggtatcaca atggatcaat tgatccaatg gaacaacatc
    13501 caaaacaatt tcatttatcc aggacaaaaa ctgacaatca aaggtagcca ggaaaatggc
    13561 tcttcgacga ataattccgg taacaatacc aattcttcag gaaatgctgg tacatcaaac
    13621 ggaggacaaa caactggtgc gaaatacact gttcaatctg gtgattctgt ttggaagatc
    13681 tcaaatgatc acggaattac gatggctcaa ttgattgaat ggaacaatat caagaacaat
    13741 ttcgtttatc caggacaaca gctaatcgta tcaaatggcg gttcttctaa tgctggagca
    13801 aatactggct caaatactgg gaatacaagt ggctctagtt cgtccagctc aagttcttct
    13861 aatacagctt caggaacgaa atatacagtt aaagccggag actctgtttg gagcgtctca
    13921 aataaatacg gaattacgat ggctcagcta atccaatgga acaatatcca aaataacttt
    13981 atctacccag gacaacaact gactgtttca aacagtggat caacaaacag cacgtcaggt
    14041 aatacaggtt cgtcaaccaa tacaaataac agcagttcag ttaatactgg cagcagttcg
    14101 tctcaaggca cttataccgt gaaagcaggt gaatctgttt ggagcgtggc aaataaaaac
    14161 ggcatcacga tggatcagtt aatcgaatgg aataatatca aaaacaactt catttatcca
    14221 ggacagcaat tgatcgttaa aggtggaact tcggcaaata caaatacagg ttcaactact
    14281 tctgcagcga aaccaaatac accgaatacg tctgctacga caagtacatc atccactggt
    14341 aatacgatgt ataccgtgaa agcgggcgag tcagtttgga gcgtagcgaa caaacatcat
    14401 atcacgatgg atcagttaat cgaatggaat aatatcaaaa ataatttcat ctatccagga
    14461 cagcaagtga ttgtgaagaa aggttcatct caatcaacaa accaacaatc agttactggt
    14521 tcgaaaacct atactgtgaa atctggagaa tctgtttgga gtgttgctga cagtcatgga
    14581 attacaatgg ctcaactaat cgaatggaac aatattaaga acaactttat ttatccaggt
    14641 caaacgttga ttgtagctaa ataaaatagc tgttcgaaga aataacgatt gaattccaca
    14701 aaaatatttg ttactataag gctacttaaa tatgacaaca cttgaaaagg aagtagtaaa
    14761 aagactgaag tttcagagag cgcatggctg gtgagaatgt gcacggatgc ttttgaactc
    14821 gcctttgagt tgcccttgct gaatacccga gtaagcaagc ggcggtgacg gccgttacaa
    14881 cgttcgaggc cttttcacta aggtaaaatt aggtggtacc gcgtagatta cgtcctataa
    14941 aaagagcaat ctttttatag gattttttta tttcttttgt gaagtttgag aaaacaaagc
    15001 aaaaggaaat aaaaataaac agattctgcc ggttttttcg ttatatttat aatagaaaca
    15061 agtgttttca atagaacagg aggacagcaa atgagttaca atcataaaga aattgagaaa
    15121 aaatggcaaa aatactgggc aaaaacgaat actttcaaca cccatgatga tcctgaaaag
    15181 ccaaaatttt acgcactgga tatgtttccc tatccatccg gtcaagggct acatgtaggg
    15241 catcctgaag gttatacggc aacggatatc ctttcacgtg tgaaaagaag tcaaggatac
    15301 aacgtgctgc atccaatggg gtgggatgca ttcggtctgc ctgctgaaca atatgcgcta
    15361 gatacaggaa acgatccagc tgagtttacc caaaaaaata tcgaaacatt ccgacgccaa
    15421 atcaattctt taggatttag ttatgactgg aatcgcgaag tgaatacaac tgatccggag
    15481 tattataaat ggacacaatg gatctttacg aagctttatg aaaaaggtct agcttatgaa
    15541 gcagaagtag cggtaaactg ggtacctgaa ttaggaacag ttatttcaaa tgaagaagtg
    15601 atcgatggga aaagtgaacg tggtggctat gatgtagtca gaaaaccaat gcgccaatgg
    15661 atgctgaaaa tcactgctta tgctgatcgc ttattggatg atctagaatt agttgattgg
    15721 ccagaaagca ttaaagaaat gcaaagaaat tggatcggtc gttcagtagg agcaaatatt
    15781 gaatttaaag tggctggtac ggataaatcc tataccgtat ttacgacacg accagatact
    15841 ctattcggtg caacttactc ggttcttgca cctgaactag atcttgttag agaaattacg
    15901 acccctgaac aaaaagctgc tgtagaagct tatatcgaag agacagctaa aaaatcagat
    15961 ctaaagagaa cggatcttgc aaaagaaaaa acaggagtat ttactggtgc ttatgcaatc
    16021 aatccagtta atggcaagga aatcccaatc tggatcgccg attatgtatt atcttcatac
    16081 ggcacaggag ccatcatggc tgttccagca catgatgaac gtgactttga attcgctcaa
    16141 actttcggac tagaaattct tccagttatc gaaggtggag atgttgaaaa agctgcttac
    16201 acagaagatg gtacgcacat caactctgaa tttctagacg gcatgaacaa acaagaagca
    16261 atcgataaaa tgaatgaatg gctagaagaa aatggcgtag ggaaaaaaga agtcagctat
    16321 cgcttacgtg actggctatt ctcccgtcaa cgttactggg gtgaaccaat cccaatcatc
    16381 cattgggagg acggaacagt cacagctgtc ccagaagaag agctaccatt acggttgcct
    16441 aagacaaaaa acatcaagcc aagcggtact ggagaatctc cattagcaaa tatcgaggag
    16501 tgggtcaatg tcgttgatcc tgtaacaggt aaaaaaggcc gtcgcgaaac gaatacaatg
    16561 ccacaatggg caggaagctc atggtattac ctgcgttata tcgaccctca taacaaaaaa
    16621 gaactagcag attatgaaaa gttgaagcgt tggctaccag ttgacatcta cattggtgga
    16681 gcagaacatg cggtacttca tttactatat gcacgattct ggcataaatt cttatacgat
    16741 atcggtgttg ttcctacaaa agaaccattc caaaaactat acaatcaagg aatgatctta
    16801 ggcgaaaaca acgaaaaaat gtcaaaatct cgtggtaatg tagtcaatcc tgatgatgtg
    16861 gtcgaaactt acggtgcaga tacactgcgc atgtacgaaa tgttcatggg gccattagat
    16921 gcttcgattg cttggagcga aaatggctta gaaggaagcc gtaaattctt ggatcgtgta
    16981 tggcgtttga tcgttgatga gaacaataaa atgcgtgacc gtatcactac attgaatgat
    17041 ggcaagcttg ataaagtgta tcatcaaaca gtgaaaaaag tgacagaaga ctatgaaaat
    17101 cttcatttca atacagcaat ctcccaattg atggtcttta tcaatgaagc ctataaagtg
    17161 gacgctctgc cttatgaata tatcgaagga tttgttcaac tactcgcacc gattgctcct
    17221 cacatgggtg aagaactatg ggcaatcctt ggaaatgatg gtggtatttc ttacgcacca
    17281 tggccaacat acgatgaagc agcacttgtt gaagacgaag tagaagttgt tttccaagta
    17341 aacggtaaag ttcgtgcgaa aagcaatgtt ccccgagact taggaaaaga tgagctagaa
    17401 aaagcagcat tagccaatga aatagtgcaa gaatatattg aaggcaaaac agtcagaaaa
    17461 gttattgcgg taccaaacaa gttagtcaat atcgttgcta attaattggc tctttgtcaa
    17521 taaggactga tgagttgtgc aaaatcaaat ctgggccaga atgaacttca ttctgtctca
    17581 gattttttgt tatttcaaat tgattaattg attgatcaaa aaggttttga ttttcatgtt
    17641 ctcaaacacg ttcaatgtct ttttcttctg aatggtcttg taagagatct ctgtaatcat
    17701 caaatttttg tctattaatc ttagtatttt ttgatgtata aactacctga aattgagagt
    17761 acataccaaa ttcataaatt ttttattagt gggactagtg attgtatgga ttttgacgca
    17821 taatgaatga agtatgagaa aaggagagac aaatggatca agaactattt attatcgaag
    17881 tattatcagc taaacaaaaa attatcgaga aagcgaaaaa aagagcgaaa agaataatgt
    17941 tcaagctttt aagcttagta tttttctctg gtttgctttt tttcggagct gtatcgttcc
    18001 tatatcgcca tatgagtgca gtagtccgtt cagctgaagg gatgcaaaaa ttaaataatt
    18061 tgtatcactt ttcgtgggga gttggcggaa taacaattgt tgtgcttatt gtttttcttc
    18121 tacttatttg gctccgttac catcaattgt cgcgtcattt cgatcaatgg cttagtcaaa
    18181 gagcacaaca gtttttacat aataaaccaa cttctcaaga tgatgactat ctttattttg
    18241 agaagacttc gacgagtcaa gcttttcgga tacaaaaaag tgattgccag ttattgctga
    18301 gatcacttga tgatttacct atctacttag gcgaaagcaa atcaaaattc ggaatgaaca
    18361 cattccatat ttttttacta gaaaacgaac ccagatggga aaaaagccag tcttcgcctg
    18421 gtggatacct gacaactaag atgagtacat tagtcactgg ttttttcctc attcttttag
    18481 ctggaacaat ctattatggg agatacactc agccaaaaat gtcttctcat ataaatgctg
    18541 cttctcacat gacaatgaac tcaactaacg atacgcatat acaaaagaca aatgaagggt
    18601 tgttagctga tcctaagcaa aaggtaaatt tgacaacaca aaagataaat gatctcaaac
    18661 ttgatacaga gacgcactct ctctatatga caacagatag tggtgctaat tgggtatttg
    18721 tgccgattga ttcgcaatgg ttgcgttttg gcgaatacac cctgacaacg gggctgattc
    18781 ctgaaggtta ttggatggac aacacatatg atatttccgc cgatttctca tggtttatct
    18841 attcttctgg ggatgatgta cgtctgctga cttcaagaga taatggtaaa acatggcaaa
    18901 cgtctattat cacccaatca gttcagccga tacgttatcg aaaagcggta ttttatggca
    18961 acgatggtct atttatctgt acatcagcca gtgggatgtc tgcagaaact ttgtacattt
    19021 acactactat ggatggcgga atcacttgga taaaaagtgg aagtacaatg atcaatcagc
    19081 cagtacaaaa tgtcagcttc gttacaactt ctttaggttt tgtttcgaca cgtgaaagtt
    19141 tgttttatac aaacaacgga ggacgctcat tcaaagaatc agttctgtcg attccggaaa
    19201 actatcagac aggggggata gatctttttc aatcaccaaa tgaagttact caaataagcg
    19261 cgaatacgtt agagacaaaa ttttatttgt tgaaaaaagg accaatcgat gcagggaaaa
    19321 tgtttgcctg cctcttccgt tcaactgata acggggaaac atggcaattc gttcagcaac
    19381 tatcgcaagt agaacaagga gattaaagaa gagagattgt gagcctgacg ttcagcaccg
    19441 agtcacaaga aacaaattca aaaaacagct tctcatattt gttgaatagt gtaactcgtg
    19501 attcggagtt gacaagagca acaagaagcg attttgaagt atagcttctc gtattttaca
    19561 agatcgtgtc ttattgccga taggttgtct cttgaacacc gtttattcgt aaaaagggat
    19621 tgtgacaagt cttttgtcac tacttaccga acgaaactga aggagctatc caaaaagtat
    19681 cattagtatt attctttgtg tttctagtgg caccactagt acatttaaaa aagctatcga
    19741 tcatggacta atcatacatg atcgatagct ttttagataa tgtttgttac gctatctgaa
    19801 attgactatt ataaagactg gcataaagcg ttggtgattg gagtagttca gaatgtgttc
    19861 ctttttcgac gatatcgcca ttcttcatta caaggatcat gtctgcattt tcaatcgttg
    19921 acaaacggtg tgcaatcaca aaacttgtcc tatcttttgt cacagcttcc attgcttgct
    19981 gaatcaatgc ttctgttcgt gtatctacgc tagaagttgc ttcatctaaa ataacgacag
    20041 gaggattcgc tagaatgact cgagcaattg tcaataattg ttgctgtcct tgagataacg
    20101 tgccgttttc gctagaaatg atcgtatcat atccgtctgg cagtgttcga ataaagtgat
    20161 cacattgtgc gatttcagcc gcttcgataa tttgttctct tgtggcatcc attttcccgt
    20221 aggcgatatt atcagctacc gttccttcaa acagccaggt attttgtaaa accatcccaa
    20281 aagaacgacg tagttctcca cgtgaaagct tggtaatatc aagaccgtcg aattcgatct
    20341 ttcctttatt cagttcataa aaacgcatca gcagattgac taaagtcgtt tttcctgcac
    20401 cagttggacc aacgatcgct accgtttgtt ttggctttac tgaaaaatcg acttgattca
    20461 tcaatatttt atctgatgtg taaccaaact gtacattttt gaaagctatt tttcctttcg
    20521 gttgttctaa aagtcttgca tctggaaggt ctggaatttc atctgtttca tctaatatct
    20581 caaatatcct atcgattgct gccattgcgg attggatcga gttgatcaca taagaagcgg
    20641 tagaaattgg ttcagaaatc tgattgatgt actgaagata agcttgtaag aagccgatcg
    20701 tcacaccacc tgatagaaca agcatagcac cgaataccgc acttatgatg aaggcgagtt
    20761 gattaatgaa acgaatggcc ggatagatag caaagttcat aaattgagca cgtttaaaag
    20821 cgttgtattg ctttttattt acttcgtgta tagcagcttc tgcatgagct tgctgattga
    20881 atgttttgac cactagatta ccagctaaga tttcttccat tcgattattt aaaacaccca
    20941 gttcatactg attctgttca gaaatctgtt tgtttttgtt cgcaatctta gttgtaacaa
    21001 ttgaactgcc aacgatcagc aataagacga gcaaagtaag cttgctttcg atataaaaca
    21061 gcatcagacc agcagcagct attgttacga cagaagtaaa aaattgattg atatctgtca
    21121 ataacacttg agaaagttga ttgagaccgg tagttgtccg actaatgatg tcacctactt
    21181 gatgattgtc aaaaaacgac atcggtaatg ttttgaattt ttttgtgatt tcttttcgca
    21241 ccctcaatgt gatcttttcg cttaacgctg ccattgtccg ttcctgaata aatgaagtga
    21301 tgctgcttaa gactgaacag ccgatcagca ataagacagg gaacaacaat gcttgtttga
    21361 tatcactgaa agaaagctgt ccaatacctg tttttcttat ttctgataag agatcatcga
    21421 tcccgattcc catgatcaag ggcatggcta cgactaatag gttcccgaat aaactgcata
    21481 gaaacaatcc gtaaaaatat ttatgttcag gtttgatcat tttccaaaaa cgtatcaaag
    21541 cacgcgtgtt caacgttttt ttcttttcca tcgtatccct tctttctata ttccttgtga
    21601 ttttgcaaac tcctgataag tttggcaatt agacagtagt tcttcatgag taccttgtcc
    21661 aacgattttt ccttcatcta aaacaatgat gttatctgct tgttggattg tactgaggcg
    21721 ttgagcaaca atcacgagag ttttctccga catgtgttta tgaagggctg ctcttaatgc
    21781 tgcatctgtt ttatagtcta aagcggagaa actatcatcg aatacataga tctctgctgg
    21841 tttgatcaac gctcgagcaa tacatatccg ctgtttctgg ccccctgaat aattagaacc
    21901 gccttgagca acaaagctgt ccaatccgtc aggaagggtg tccactagtt cttctaattg
    21961 agcgatcttg atcgctttag acaactcttc tgttgaggca tattcatttc ccatctgcaa
    22021 gttgcttaaa attgtcccgc tgaataagaa agccttctga gggacataac tgatgtggga
    22081 gcggatctgt tcttgagtca tttgagtaag aggaatacca ccaagggtta cttttcctat
    22141 cgtagggtca ctaagtctca agagaagttt cgccaaacta ctttttccag atccggtccc
    22201 gccaacgatc gctgttgttt ttcctttagg tattgtgaaa tcaatatctt ctagaactgg
    22261 atcagagatt tcagtatatt taaatgtgac atgttcaaaa gcagctgcat ttgtctgatc
    22321 aaaggttggt tcagctactg ttttgatcgt ctcttcctca atttcgatct ctgcttgcag
    22381 tatttcttct atccgtcgta atgaggcaaa cgatttaggg ataatgacca ataccatagc
    22441 tgcgatcatc aagtaagcaa gtgtcagcat agagtattcg actacagcag tcacgacacc
    22501 gatttgtaat gctccttctg ctacaagatt tccgccaaac cacaaaatag aagcataaac
    22561 gattcccatg agcaaaaaag caattggagt gacccaagca aatattcggt tcactttgat
    22621 catttgatta gcatagtcag caaagctctt attcgttcgc ttttcttcat atgattgatt
    22681 atcaaaggca cggatcatat taatcccagt aaagaattct ctcaatgtga tggtgatccg
    22741 atccattttt ggctggatac tcaaagataa aggtgcccct cgtttcatca gtcgataaac
    22801 aatccataca taaaaaacaa cagagatcaa tgtaacccat gttagtaata gagaataacg
    22861 aaacatcatg agaatggtga aaacgcaaat aaccggtgct ggtaagatca tttggcaaaa
    22921 taaaacaatc atttgctgga cattatcgac atcattcgtc attcttgtca aaagagatcc
    22981 agaactaaaa cgactgatat ccttcattga cagctgttgg aatttacgga aatatttctc
    23041 ccgcgtttgg aatccaaacc tagcggaagc caatgctgaa aagtaactag aggcaactgc
    23101 agcgattgtt cctagaaacg ctacaagcag catttcaact ccaatttttt ttataactga
    23161 ggcttcgcca cttgctatac ctgtgtcgat cagctttgct actaattttg gtacacctaa
    23221 tgtaccggcg atttgtaaac agatcatcac aaaggtaagg agagcgagtc ctttgttttt
    23281 ctgtaagaat gtttttaaga tagacatatt attcctcctt ttttcctgat acttttcgat
    23341 tctatacctt caagtaactt gaaggtcaat agaaaaaaga ataaactgaa aaagaggtga
    23401 gaaaaaatga aaaaaatgta tacgattggc caagtatcgg aactatttga tttgccaaaa
    23461 tcaacgatcc gctattggga tgaacaagga ttaatccgtt caagtagaca agaagagaat
    23521 gattatcgat tgtttgatat cgatgatatt tttatgcttt atgatatcgt tttttataga
    23581 aaattagata taccgatcaa acagatgaag aatttatatg gaaaaacatt gacggagtta
    23641 tatgagacac ttgatgaaac agaaagaaga atccataaag aactggtggt gatgaaacaa
    23701 aaacaaaaag agataaggga gcaaaaaaaa cagttgaaat tgatgatcga tacaaacgag
    23761 gaagaatttc ctgtagaaga gatccctttt gactgtatga tctcaacgga gtttgaagat
    23821 attgtggaaa tcaaaaaatt tctacctaac tattcaagct ttgggatgat gagtatgcca
    23881 gcttccagtt cacagacgat gtatggattt tttatcgacc ctagtgaagt acatttattt
    23941 actcaagacg tgatttggga gaaaaaagat acggctgttt atcgtcgatt cttattgaaa
    24001 tccgagatga accatgcgga acgtaataat attttagaaa tcagagaaag aatgtatgaa
    24061 aaaggatgga aaacaggaga agtgatcggc cagtatctat tgacgaatac ggatgaaaac
    24121 aatatcagaa ctgaatatta tcatgcatgg atagaaatga aaaaatagga aatatgtgtt
    24181 taagataact cgaaaatgat ggttgtttta gttataaaga aaaattttct ggttcgatta
    24241 cgggtttaat gtgggggatt attagtcgtg gatagataga attttagttt tttagaggaa
    24301 atatgtcttt aaaaatggaa tggttgcaat tcttagcgat atatacgatg taattgtcct
    24361 cttaaaaaag tatggaaaaa taattgtatt gggtgttatg tataattcat ggtgaactga
    24421 gactaatgag aagaaaaatt catattgtta tgagtgagat tgtatcagat gagaatgata
    24481 aattaaatag gtgcataaaa gcattacact taaaatacat tgttgcttac attattacaa
    24541 tatgttaata aggcaaaaat aaatagatgg attgaataaa catatttttt aatcaaatag
    24601 tccctactgt gactttcctc agctatcggt gatactaccg atagcatttt tttgcttata
    24661 aaataattat aagtatttag agatttttct tctaacattc ttcaaacaag aaaaatcaca
    24721 aaggttattg ttatttttat atattctttt taagaatgat tattttttta tagaaatttt
    24781 aaaaaataaa acacgttatt gatggatagt tagtttgtta tttggtaata ttatagaagt
    24841 tgactggtag tgatttattt ttcgttgttt tataaaaatg ttattttttg gaaaaattca
    24901 caaatatgta acgaatgttt ttctggaatt tgctgtgtta aaaagcagta tgactaatat
    24961 aaatactatt gtcatttatg caatttttta tggatagtaa ttttagaggg gaatcaatga
    25021 aggaagaata gaagggaaaa atagttgcaa atacgccagt tagcaaaaat agcaatacat
    25081 cttcaagctt taaaattcga gagaatcatc ttggtagtgg aatcaactac aacaaaagga
    25141 ttaaaccaat taatagatag aattaccaat ggaaaaatag aaaaggtagt tattctatac
    25201 aaaagttgtt taattcgctt cggttatgaa cttagtgaaa ccctttgcaa tatatggtac
    25261 agaatataga aattattgac attacagaaa atgatgaaga tttaatacag attgtcacta
    25321 tttgtagata ccttttacaa ggaaaccgag ccaataaagc taagaagatg attaaggagt
    25381 tgatggaaga cgatacaagt taagaaagta aaactacgcc caaataaaga gcaaaaagag
    25441 taattggacg tggaaaatgc aagaaatgaa ccatcgattc ggtggacagt ttattagtaa
    25501 tgacggtttg agaacatcca tgacgagaat gaaggaacat cctaaatgcg tttagttgaa
    25561 ccaagtgcca aataatatgg ccaaataagc gatcagttat cgatgaatcc caagtattct
    25621 aaactatata ttcattttga tgctaagcat tgatatattt ttttgggatt gatgaaggtt
    25681 aaccaataca gggactcact gatgaaattc tagagtctga ccttggtatc aacgatttag
    25741 tgattgtttc taatggaaaa gtataaaagt atataagtac attaacaaaa taactattag
    25801 ggttacgctc cagcttgtgc aaggcactgg caggaggaat cgtgaaatca taattatggt
    25861 taagccacac ggacaactaa aagtcataca aagctatcga atcaatcaac agaagacaat
    25921 cggcaatcat tagctttgtt tacagcttac attgcaacgc ttgagttgaa ccgaaaatac
    25981 gagggaggta acgcagccat tttgagttgg ggaatctttt tagaaaatta tcgggtacct
    26041 tgttgtttag tcaaaattat aagggggagt aatagtgagg aacaaatttc ataaactgtt
    26101 aagtatgttt ctagttatgc ttattgtgat caatcaattt gggaacataa cggttctagc
    26161 tgagtcttta gcagaacagc cagagcgttc gctgacgatc gaagttgatc aagaggaggc
    26221 tgctttgggt gagcagttcc agttgcgagt cagaggaaca ccagacctgc taaatgcatt
    26281 ggtcattgat aagagtgagg atttgattga aggggaagtg aagcaactca atgattacga
    26341 acgtctgatt acttattctt cccagcattc aggtaaatac gaattgaccg caagaagcgg
    26401 tgatattcaa tcaaatacgg tctcaataga aatcagtgta ccagaagaaa gcacaagtga
    26461 gtcttttaat gtaccagaag aaagcacaag tgaatctttt aatataccag aagaaagctt
    26521 aagtgaatct tttaatgaag ccagatcatc tgagccatct ataacgcagg aatctcagat
    26581 tgaaagacaa gaggagctct tgaattatga catcggcatc tctgctgagc gccccacttt
    26641 gccgagcagg catacacaaa cgttaaaggg atacattcaa ggaggcgctg gcgatattct
    26701 tgaagaatat ggggagatgg tcgtacgagt tcctagagca tcgattggct taattgagtt
    26761 cattagagtg gaggtcgctg atgattcacc tttaaagcca ctggcatttt accaagaagg
    26821 cacagacgtt gtttttccat ttacctttga ttatgaagga ttaaatgaag ccgctcagtc
    26881 gtatacattc agtatcacgt ttgaagttgc tttctttcaa tcaggcggta ctgagccaaa
    26941 taatgacttt caagtgagtc ttacttatgc tgagcgagca gcaaacacgg aattttcaat
    27001 tacgcctatt ccttcatcaa gacccatttt ttcgaaatta tactatggct ctagagaaat
    27061 cgacagccaa ggaaatcttg ggaatctgct gattgacggg caagacgtga ccaacagtaa
    27121 taaatttatt ttgcaggtaa attatgaagg atcacgaaaa gacggtgtag tggttaccga
    27181 tgtactaccg caaggaacaa ctttggcacc gaatccgact acatggagtt ccactggaaa
    27241 tagagaacct atttcaggtg gggttcggat cgcagaagta acgaatccag gtgaagcaaa
    27301 cgttagaact cattatgttt ccgaggaatt tgtggacaaa gtatctttta ataaggaaac
    27361 gaatacactt gttgtggact ttggtaatct agcagagggt caatcgtatt ttattgaata
    27421 tgctcttgaa gtgaccgatg tcgacttgtt caatgaagga agacaagagg atgggttttc
    27481 tcggaatcga gcgagtatga cctacaataa tcaggtaatg agccgagact accgcttgag
    27541 aatccctgaa agtaatcttc cggcaatctc tttaagaaaa agtgtggaca aaaatgttat
    27601 caatctcaat gaaaatgaac taacgtatac tctgcatgtc tcgatgtttt ctggaacaag
    27661 caatacgctt gttattgaag atgttttgga agaaggcatg gaatttgtgt catttctatc
    27721 agatattccc tctttcattg atgccgaagt caataatgga atagttcgtt tcagtgcgaa
    27781 taatacgatt ggtggtccga caagttttac cctctctttt aaggtcaatg tagaggcgta
    27841 tgcggtcggc gatcaaattt taaactttgc aacgcttgtg aatagtgaca atcgattgaa
    27901 tacgagtact gtaagaacaa ggaaaatcga tgggcgtatt aaagtaatta aaactgatga
    27961 gaatggccaa aggctggcag gagcaaaatt tgaaatttta tcaagcgatt cacaagtgat
    28021 acaagaaggt ataacggcag aaaacggaga atttttaagt gaaccgcttc ctgtaggtag
    28081 ctatcaagtc cgagaaacag aagcaccgga agggtatctt ttagatgcga cggtacatga
    28141 tgtttttata aatgaatact ccatagaaga agtgacgtta accattgaaa acatccttga
    28201 tacgggtggt gttgaactaa ttaaacatgc tgaaggcagt ggtgaagtcc ttcaaggagc
    28261 tgtttttgag ttacagaacc gagaaggaga aacgctacaa accggtttaa ctacaggaga
    28321 agatggaaaa ctggcaattg acggtttagc accaggagca tatcagctgg tagaaactca
    28381 agcgccaata gggtatgaat tagatgcgac acc
//
LOCUS       DAPBAF010000038        27771 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.038, whole genome shotgun sequence.
ACCESSION   DAPBAF010000038 DAPBAF010000000
VERSION     DAPBAF010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 27771)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27771)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27771
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.038"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(219..935)
                     /locus_tag="RD451_001966"
     CDS             complement(219..935)
                     /locus_tag="RD451_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HDT7567203.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(936..2759)
                     /gene="glpO"
                     /locus_tag="RD451_001967"
     CDS             complement(936..2759)
                     /gene="glpO"
                     /locus_tag="RD451_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HDT7567204.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(2773..4269)
                     /gene="glpK"
                     /locus_tag="RD451_001968"
     CDS             complement(2773..4269)
                     /gene="glpK"
                     /locus_tag="RD451_001968"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HDT7567205.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(4405..5865)
                     /locus_tag="RD451_001969"
     CDS             complement(4405..5865)
                     /locus_tag="RD451_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7567206.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(5855..7150)
                     /locus_tag="RD451_001970"
     CDS             complement(5855..7150)
                     /locus_tag="RD451_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDT7567207.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVEEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(7482..8159)
                     /locus_tag="RD451_001971"
     CDS             complement(7482..8159)
                     /locus_tag="RD451_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HDT7567208.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(8189..9280)
                     /locus_tag="RD451_001972"
     CDS             complement(8189..9280)
                     /locus_tag="RD451_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HDT7567209.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEKAYKELYLPSPLYNFLKARYQ"
     gene            complement(9381..9815)
                     /locus_tag="RD451_001973"
     CDS             complement(9381..9815)
                     /locus_tag="RD451_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDT7567210.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(10399..11856)
                     /gene="ascB"
                     /locus_tag="RD451_001974"
     CDS             complement(10399..11856)
                     /gene="ascB"
                     /locus_tag="RD451_001974"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HDT7567211.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENW
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIKDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(11853..13748)
                     /locus_tag="RD451_001975"
     CDS             complement(11853..13748)
                     /locus_tag="RD451_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDT7567212.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPIILLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSSVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(13806..15581)
                     /locus_tag="RD451_001976"
     CDS             complement(13806..15581)
                     /locus_tag="RD451_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HDT7567213.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARFPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKNISRYPLEIYLIRRFFPIHFQLRPNLAESAYFVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESWEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(15631..17127)
                     /locus_tag="RD451_001977"
     CDS             complement(15631..17127)
                     /locus_tag="RD451_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDT7567214.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     VIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRTWKEEDCAPVMLDGDEQCLQANTADYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(17321..18943)
                     /locus_tag="RD451_001978"
     CDS             complement(17321..18943)
                     /locus_tag="RD451_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HDT7567215.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESIKAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTIPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(19271..20584)
                     /locus_tag="RD451_001979"
     CDS             complement(19271..20584)
                     /locus_tag="RD451_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HDT7567216.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCVLMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLFGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFVGFMWILNVK"
     gene            complement(20829..21053)
                     /locus_tag="RD451_001980"
     CDS             complement(20829..21053)
                     /locus_tag="RD451_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567217.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(21073..21495)
                     /locus_tag="RD451_001981"
     CDS             complement(21073..21495)
                     /locus_tag="RD451_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HDT7567218.1"
                     /translation="MESVYRQERKSNRKKGQMMIQKTRVMLYVNDVEMICRFFVEKIG
                     AEISETIELPEEFKSIVLSISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETI
                     YENMEEPGEITDNNGILTFNFSDPEGNYFVIGKAESSD"
     gene            complement(21637..22347)
                     /locus_tag="RD451_001982"
     CDS             complement(21637..22347)
                     /locus_tag="RD451_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567219.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGGESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(22365..22862)
                     /locus_tag="RD451_001983"
     CDS             complement(22365..22862)
                     /locus_tag="RD451_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7567220.1"
                     /translation="MTPSDVDLLQQISIETFTDTFGKDNSPEHLADYLTQAYALEKLT
                     EELKDKETDFFLVSIDQEPAGYLKLNTGTSQSEEMADHFLEIERIYVRKKFKHQGIGT
                     FLLDTAIEKAKEKQKTAIWLGVWEHNDVALAFYRKKGFIKYSEHVFYMGDDPQTDYLF
                     IKQLF"
     gene            complement(22899..23351)
                     /locus_tag="RD451_001984"
     CDS             complement(22899..23351)
                     /locus_tag="RD451_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDT7567221.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(23486..24091)
                     /locus_tag="RD451_001985"
     CDS             complement(23486..24091)
                     /locus_tag="RD451_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HDT7567222.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(24541..25161)
                     /locus_tag="RD451_001986"
     CDS             complement(24541..25161)
                     /locus_tag="RD451_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HDT7567223.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(25163..26032)
                     /locus_tag="RD451_001987"
     CDS             complement(25163..26032)
                     /locus_tag="RD451_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase family
                     protein"
                     /protein_id="HDT7567224.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANEAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(26055..26462)
                     /locus_tag="RD451_001988"
     CDS             complement(26055..26462)
                     /locus_tag="RD451_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HDT7567225.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDKHKLAKLYEQVGLKFSELYVNDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(26481..27770)
                     /locus_tag="RD451_001989"
     CDS             complement(26481..27770)
                     /locus_tag="RD451_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDT7567226.1"
                     /translation="MGVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGGFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     VLLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFNNATATDVDTVAAALLYAWILSPVLKAF"
BASE COUNT         7895 a         6027 c         4574 g         9275 t
ORIGIN      
        1 tcatgtccta tccttattag aatacaaaga tattgttttc ctgacaggta ccgtttcata
       61 agcacaccaa ataaactttg tttattggct attcgactta ctgattagat accagctaca
      121 ctcacaaaac ataccccatt cttctaggtc ttatttattt tccacttaac tatagcaaga
      181 cacattttgg ttgtcaaact ttagtatgtt ttatagattt acaccattaa tgaatagaca
      241 cctaccgcga taattgctcc gatcattgga cctgcgattg gtacccatga atatgcccaa
      301 tctgaagttc ctttattagc tattggcaat accgcatgtg ctaatcgagg accaaagtcc
      361 cgagcagggt tgattgcata tcctgttggc cctcctaatg aaagaccgat ggctaagatc
      421 aatccaccta cagcgaatac gttcgttcca ggtgcaaatt cgttttgtcc aaaagctagc
      481 aacccaagaa ctaatacaaa tgtaccaatt aattctgtga tcacatttgc tggataattc
      541 cgtatagcag gacctgttgc aaacgttcct aaaatcgcgc tttcatcttt cgttgcattc
      601 caatgtggca aataagaaag ccaaacaaga atggcccctg caaaagctcc taaaacttgc
      661 gcaatgatga aaggaacgac aagattccaa ctaattgccc ctgtcatcgc catagctaga
      721 gagactgcag gattcaaatg agctgggccc atgaatccag aaatatagac agccattgtt
      781 acagcgagtc cccaaccaaa tgcgatgaca atccagccag aagcctgtgc tttacttttg
      841 tttaaattca cagccgcaca cacaccatct ccaagcaaaa ctaggatcag tgtcccaata
      901 aactccccca tgatttgagt catatcactg ttcatttatt tctccccctt tagttcccgc
      961 agatctgatt ctgcaatcaa tgcttctaaa cgtttagtct gttgcgcctt ctcctcttct
     1021 gtccattcaa aatatccagc aattgcatcg atcacaggtt gcttgatctc atcaagctga
     1081 tctcgttcaa acaacagatg atttgtacga cgaatgagat aatcgcctgg ggccaaaacc
     1141 atttcttctt ctaaaccata acgtaaccga gctgactcag cgagactcaa accaggataa
     1201 ggtgccattt cttttgctaa ttcaaagata cgtcgggcat tagtcccgta aaaatcagcg
     1261 atataagtag catcttcttc ctctaaaccg gctgctactc cttcttttgc taattctgtc
     1321 actgtttctt ctaatttagt tggatcgaag tttccacctg aaatctgata ttttttagag
     1381 tcgatttctt tcgtctctat tccgtattct tcttttaata attggcgtat caatcgcaaa
     1441 gctccttctg ccatcttacg gtaatcggtg attttcccac cagataaagt cagcaaacca
     1501 tctggttctc tttctaaaga actacctctg gaaatcgtag aaggtgcttt ttcatcacgg
     1561 ctgttttcca aatggttcaa cacgtcttct acttcagcac gagaaacttt gttttcctta
     1621 tattcactta ctgtatcgac aactttattg aagctcttgt ctgaaatcga tccattatct
     1681 ccaccattgt aatcagaacc agaattacca atcaacagtg gacgaagtcc tgcccagctt
     1741 gcttcgatat cattcaatgt gatatttgct tctggatagc gatgattgat cacatccaat
     1801 agataatcta catcttcttg tgtgactttc ggatccgtaa aatctccttg gtaatccgta
     1861 tctgtcgtac caaagtaagt cttgttttct cttggaatag caaaaaccat ccgcccatct
     1921 tgctttcctg tatcgaagta tgtgggttgc ggtacaggca gttttttcgc atctacaact
     1981 aaatggatcc ctttagttgg acgcatttta ggagagactg gacgcgtaaa attcaagttt
     2041 cgtactttat ctacccaagg accactcgta ttgatcacta attttgcttt gatttcgatc
     2101 acttcatctg tcagcaggtc acgagctttg acgccaacga tttgatcgcc atcatataaa
     2161 aagccaaccg ctttcatttt acttactaga taagccccat cttcggcagc ctttttgata
     2221 ttatcaatca ctaaacgggc atcattgttg cggaaatcta gatagacacc cgcgcctttt
     2281 agcccttctt ttttcaaaaa cggttctctt tccaatactt cttctggtgt cagcgtataa
     2341 ttctcatatt tggttcctgt cacatttgcc agtttgtcat aaaggtccat tgctactttg
     2401 accgagaaca tattgaaggt tgttgctcct tcgccctcat agattggcaa aagcattgga
     2461 tctggttttg ggatgtgtgg ggcaatactt tgtacgactg cacgttcacc aactgtgtca
     2521 gctactactt ccacatcaaa tgtcttcaga taacgaatac cgccatgaac aagtttggtc
     2581 gagcgagagg aagtcccttc tgcaaaatcc tgcatttcga tcaatcctgt tttgattcct
     2641 gatgctgctg actggactgc cacaccggca ccagtgattc cgccaccgat gatcaacaga
     2701 tccaattctt cttgctgcat tttttgaatg ctatcttgtc ttgtcttgtt tgaaaacata
     2761 tggatttcct ccttattcaa atgcttgggt agcttttact gcttttttcc aaccgttgta
     2821 aagtttttct cggcgctctt cctccatttg aacttcaaat agcttgccag cttcataaaa
     2881 ttcgcggatc tcgtctgtat ctttccaata accgacagct aatcctgcta aaaatgctgc
     2941 ccctagcgcc gttgtttcca agttttctgc tcgttggatc ggtacattca agatatctgt
     3001 ttggaattgc atcagatatt cattgtttgc tgcaccgcca tctactttca atacaggaat
     3061 cttgattcca gtgtcatctt gcatcgtatc gatgatatct ctcacttgat aagcaatcga
     3121 ctgtaaagta gctttaatga tatcttcttt tgtcgtacca cgtgtcaagc caaacatagc
     3181 ccctcgtgct gcctgatccc aataaggagc acctagccca acgaatgcag gaacaacata
     3241 aacctcatct tcgcttgtag agcgtttcgc tgcgtcttct gaatcgctag ctttttgcaa
     3301 catttgaagt ccatctctca gccattgaat cgaagaacca gccacaaaaa tacttccttc
     3361 taaagcatag taaacctttc catttatgcc gtaaccaatt gtcgtcaata aattattttt
     3421 ggataattgc ggtttttcac cggtattcat gacaataaat gaacctgtac cataagtatt
     3481 cttgaccatg cctggttcga atgccatttg tccgaataat gcggcttgct ggtctcctgc
     3541 catccctgaa attggtgctt cgcttccata aaaatgataa ccttgcgtat aaccataaac
     3601 ttctgagtta gaagtgactt ttggtaacat cactcgagga atatttagta aatctaaaat
     3661 ctcctgatcc caatctagct gatggatatt gaacaacatc gtccgactgg cattcgagta
     3721 atcagtaaca tgtgcttgtc catcggtcag tttccatact aaccaagaat cgatcgttcc
     3781 aaacatcaat tcgccttttt cagctcgttc ttgcgcgcct tctacatgat caagaatcca
     3841 gcgtatcttc gttgctgaga aataggcatc gatcactaac cctgtttttt cgtggaaaaa
     3901 ttcttgatag ccttcatttt ttaagttatc tgcaattcca gctgactgtc tggattgcca
     3961 aacaactgca tgatagattg gacgtcctgt atctttttcc catattactg ttgtttcacg
     4021 ctggttcgtt atgccaatcc cagcaatctg atttggtttg atccctgatt cgatgaacgc
     4081 tccggcaata actgactgta cagaattcca gatttcattt gcatcatgtt ccacccaact
     4141 ttcttgcggg aaatattgcg tgaactcttt ttgagaactg ccgatgtgtc ttcctttctt
     4201 gtcaaagata attgctcgtg agctagttgt accttggtca atcgccatga tatacgttga
     4261 ttctgtcatt gtgattccct ccattatatg caaacgcttt ctttaactac tcttatcata
     4321 ctactgtttt aaaaaaagaa actgtcaaaa ttttattctt tttttctttt tttgacagtt
     4381 ttttattatg aagctatttt ttaatcaatt cttttctttt ttcagcgtct ctattcttct
     4441 tttcaatcga ataatgtcgt aaggtgacgc aaattctgac agataatatt cacactgttt
     4501 tttgtttctc tggcaaaatg tgatcaccaa atcatattct ttaccttctt cataacttcc
     4561 aatctcaata ccgccgattc ccctcagttc tctgatcaga tattgttgaa aagcaatacg
     4621 ataaatcggc agactttcta aatcgattcc aatcactact ggttttgcaa tataaaaatc
     4681 gatcatcaaa agaacattgg catactggat catcaggtaa ctaagctcac tatcttcagc
     4741 tcttttcctc ggcaattgct gcaccgctgt ttcctgtaat ttcgccagta actgtgttaa
     4801 ggaatgcccg agcattttct gctgctgttc caaaagccga tcacgctcat agacttcgat
     4861 ctttccaaca aagaaaaacc attcattgtt gatctgggaa atttggtagc ctactgcctt
     4921 ttcttctttg attttcaaac gacgaggacg ataatgccat aacatcgttt cccgaatgta
     4981 agtatctaaa acagcggttg gtaacttttt gctccgtgtc aaatcatact gataaaatat
     5041 ttcttcgtct actatcgaaa aagaaacaaa aaagctgtaa aacatcattg tttcgtatac
     5101 attcagttct gctgctgttc gactaagatg catcacgatg attggatcga ttgcttgata
     5161 aagccggtcc gactgataga gtaatttctt ttctttcaaa gttgcgtacg tacttttttc
     5221 attcaatagt ctttttttcg taatcccgag ccagcaagca atctgtgctt ctgctgatgc
     5281 cgtaaacgtt gtttctaata cacggtccaa tcctagaatg aacggtcttt tttctggtgt
     5341 attttgcaaa aaaagcggtc gctgatcttc cgggatatat tggaatagtt cataataaaa
     5401 atatcgtatc tgtagctctt ctccgtataa ttgaccgttt ttgatttgta atccaaattc
     5461 ctctaagagc tggttcaatt ctttgatctt tcgaaaaaca gaagactcac tgatattaaa
     5521 cgctgtcgct aatcgaacga tggatacttg ctgatgttct aataaataga cgagcatctt
     5581 aaacttcaag ctttcctgca ataaaaacaa tagaattttt tccaaactta catcttcgtc
     5641 caacacaagc agcgcctgat actcatttcg ctgtacttct actttttttt ccatcattcg
     5701 gccaatcaat tcaatatctt ccaaatattg atcaaacgag gcttttgaca gttggacatg
     5761 ctctctcaaa ccattgatag aggctgttcc cccttgcaga acaaggtttc gcaaaatcag
     5821 gatctgtaac tgctcttttc tttctaataa tgcttcaatc ttcataggca gtattcgcca
     5881 cctttgacca caccatatct ggcacacggt attctggctg gaaaaatagc tcatgttctt
     5941 ctaactgttc aaacgtccat ccttcttcta ctgcaattgt cagttggtca agaaggtgga
     6001 acatctcttt tttgctttgg agctgtgctc caagaatctt tttttcagaa tcaaatagaa
     6061 atttgagttt aactttgctt tgatttattg ctgtaagctt gtagtctacg tatcctgttt
     6121 caattttttg gggataaaaa atgctctctt cttctgtcaa acctacgctt cctaagaaat
     6181 agccaaacca ctgattgccg actggacgat aggttccctg atcctttgtc tgtgagccac
     6241 taattgtctt gctgacattt cgtgctgtac ggacagcgtt atttactaga gaaacataca
     6301 ttttttcatt tgttggacga aaagttactt ggatcgcatc gccaatcgca taaacgtctt
     6361 tttgagacgt ttgcaagtag tcatctaccc agatcgttcc atcatcattc aatgttaatt
     6421 gttcttccca catctgattg tcgggacgag aatgattagc cagcaaaaca agatcatagt
     6481 tctcctttct tttttccgtc tctacaatag cggtttcatt ttcggtcaaa gacacaactt
     6541 gttcttctaa aaaaagtgaa agcccttgat ttttcatttc ctttactaac ggttctgtca
     6601 tttcaggatc tagataacga aaaagaattg actttcggct ttcgtaaaga tggatttgtt
     6661 tttttcttga tgccaaccct tcagctattt cgattcctgc ttgtcctgca ccaataattg
     6721 caattttctt tgcattcatg atcttttgct gaagagccgt tacgttttgt atctttttaa
     6781 ctgggtgaat aagcgttgat tctgcagaaa tatttcgaaa cttttgattt gaaccagtcg
     6841 ctagaatcaa acgatcaaaa tccaattttt ttcctcctgc taaaacgact tttttttctt
     6901 tcaatcctat tactgtcttt tctgtgtaaa catggattcg atagcggtca gtcagttctt
     6961 ctttcgtgat ccaagaaagt tgtttttcac tggtaacctt tccttttaat atcaaattga
     7021 acccgctggg aatccatcct aacttcgatt gcttttcaat caaatatatt tcacttgttg
     7081 gcatcaattg gcgaagataa atagccgcat gaatccctgc aaacgacccg ccgacaatta
     7141 caatgttcat ctgcattcct ctttcttata aggtgttcta ctgctaactt ctcaatcaga
     7201 aaacacagta ttcataactc gctttcaacc ttatgataca tagcgatgca gcagaatcaa
     7261 ccctctccat cataccgtgt tctaggtctg cttctcaata atgtactagt ggacctaatt
     7321 gaagagtatc atttctgaag agatgtttca aaaaatgtac tcttataaaa gaaaaaaact
     7381 cgccttttac gtacctctgt ccaaatagga aacagaaaag aacgaaaaga cgagttttag
     7441 cgtgtgtaat gtaatagtta gaatagacac atcatttatt tttaattctt taatgcttca
     7501 acaactgctt cgcctaattg atgagcagat tgaggatttt gccctgtaag aagccgccca
     7561 tcaatttgaa ccacttctga aaaagctgct ccagactgat agtttgctcc tttttctttc
     7621 aaagcatctt ctgctaagaa tggtacttca ttcgttgtac catttgcttc ctcttcttca
     7681 ttactgaacc cagtcactgt acgtccagct aaaatagatt ttccagactc atctgtaact
     7741 ggcaacaatc ctacaacacc gtgacaaaca gctgagacca gcccttcatt tcgatagatt
     7801 tgtgaagcga ctttcccaag atctattgct tctggaaaat cccacattgt tccgtggcca
     7861 ccagcataat aaaccgctgc ataatcattt gcatccacat catcaggacg taaggtattt
     7921 cccaaggccc gatttctgaa atcttcatct tcataatagg cccaatcgat ttcatccata
     7981 ttcaaaacac tttgcggttc taaaggtaca tatccgcctt taggactgac aaaatctgca
     8041 tcgatcccat tttttactaa tacatcataa aaatgagtca gttcacttaa ccacaaacct
     8101 gtaggacgct cgatcttttc gtacttttct acatttgtta atacgatcaa tactttcatt
     8161 ttcccatcct ctttctataa aaattgcgtt attgataacg tgctttcaag aaattatata
     8221 atgggcttgg caaataaagc tctttatatg ctttttcaaa aggtttcgtt acaaattcat
     8281 cctcacggtt ttccaataat ttctctgccc agtcaggatc gacgatcatt tgctgtccaa
     8341 ttgctgcaag ttctgcatat ttcaatacct gctctacatc ttcgcgattg cggatcccac
     8401 cgacaccaac taaagggatc tttccttgaa tcgtgttatg gaccacttca agaatcgatt
     8461 tatcgttgta tttatcagaa cgagctattc gatcatacat atttaatgaa acatgcagat
     8521 aatctagttt tgactcacgt aatcgttcaa gaagccagat cgtgtcttca aaacggatac
     8581 ctggtgtttc atattcttct ggtgagaaac gataccctac gatgaatggt tttttagcat
     8641 attgttcaac cgctgagaaa accgttgtta ataattcttc aataaaacga taacgatttt
     8701 ccaagctacc gccccattga tcctctcgtc tattcgaatg cggagagaaa aattgttgga
     8761 tcaaatacgt atttgctcca tgcaactcga ttccatcaaa tcctgattca atcgctctac
     8821 gtgtggcttt gccaaatgct tggattgttt caacgatttc ttcttcactc attgctcgtg
     8881 gtgtttccgc atcaggacgt tttgctgcaa ctgcacttgc agatacaggc tgttctccag
     8941 ataaagttgc tcgacttgtc attcgtccac cgtggaaaat ctgaataatc gcttttgcgc
     9001 cttctccttg gattgctttc gctagctcac ttaatcgagg aatcatttca tcatgagcga
     9061 tgctgagttc acctggccag ccttttccga tatcttggac atttgcagca ccagtaataa
     9121 cagcaccaag acctttagaa cgttgtttat aataagtgat ctcatcttcg gtgatcactc
     9181 cattgaaaaa gctgagttgt gtcgtcatag gcgacagcat caatcggttc ttcaattgaa
     9241 ctcctgaagg taaagtaatt gattgatcaa attgtgacat tgtcattcct cccataattc
     9301 gctctgatta acctatcgag aatcatctat cattaaacca ctcgattagt tgtacatgca
     9361 actaatttgc ttaaaaaatt ttattttttt tgtaacttat ctgttgcatc attcattgtc
     9421 tgggctaatt ctttacttgc ttcatttccc aaaactgctt tgtatgactg atgaagttct
     9481 tcccagctac catcgacttc cttagcaaat tggcgtcctt gttctgtaag ataaactaat
     9541 gacaagcgac cttcgctaac tgttttgacg tatcctttat attctaattt ttcaacaaaa
     9601 cgagcaatcg ttgatggggc ggaatagagc atttgtgcaa tatctttttg tggtattcca
     9661 tctttttctt ttaatatcaa taaaataaaa ccataagttg gtgccagacc tgtccttcta
     9721 aacgcttcat cagctaattt attcaacatg cgatctagct ttttcacgct aaagaaaaga
     9781 cattcatcta acgctttttc aattggcttt tccatttcat cccctccatt ggcgtacata
     9841 tcatagtatg atttttattt tttgtcaaaa aacacggaat aatgtccgcc tcctctgtct
     9901 agatttgaaa aaaagaagta gccatcttca aagaatttcg gcttgttttc gacaaaactc
     9961 cttctggaac accgtgaatc agaggttgtg aaaaagtcgt ttagttttga gtatgaagaa
    10021 aaattttgtg aaaatggctt tccacatttt tgcataaatt tggcttaata ccgaaaaact
    10081 ggcttttgaa caccgtttat atcagaggtt gtgaaaaagc cgtcctgcat caagtaataa
    10141 gaacagccaa acaaaaatag ttcctcatat tttgtcgttt tttgagctaa tgccgatggt
    10201 cagctgattg tacaccgttt attgagaggt cgtgagcctg ccgttgaact ccgagtcaca
    10261 aggagcaatt tcaaaaaaca gcttctcatg ttttatgact atggtgactt gtgatcgagg
    10321 agttggcagg agaatactgt ttattcgtaa agaaggggct gtgacaagac ttttgtcaca
    10381 gtcccttatt tccttttatt ataggatttc gccatttgat tggatgactt gtctgtacca
    10441 atcaaatgat tttttcttta accgtttctt tgtgccattc ccttcgtcat cttgatcaac
    10501 atagatatat ccataacgtt ttgacatttg tgaagtagaa gcgctgacga tatcaatgca
    10561 gccccacgac gtataaccaa ataaatctac tccatctttg atagcttcct tcatctgctc
    10621 aatatgctgc ttcaaatagt caatgcggta atcgtcttga acggttccat cttcttctac
    10681 tttgtctata gctccgagtc cgttttcagc tatgaacagt ggtttttgat acctatcata
    10741 taattgattc aaagcaattc tcaaaccctt aggatcaatc tgccagcccc attcacttga
    10801 tggaagatac ggatttttaa ttcctccagt tattaagttt ccttggaccc cttcccaatt
    10861 ttctggatga gcactgactg cactagacat gtagtagcta aaagaaacaa aatcaacagg
    10921 gtaggctgct aagatttctt catcacctac ttctattttt aagttgacac ctttttcttc
    10981 aaacattcgt tgcgtatacg ctggataata tcctcttgct tgaacatcac taaagaacaa
    11041 agaagttctt tgctgctcaa ttgttttttg aatatcatcc ggatcacaag aatacggaac
    11101 aagaagctga tagctgatca tacaaccgac ttgtgaacct ttgataattt catgacaagc
    11161 ttttgtagct aaagcacttg ctataaactg atggtgtgca ccttggtatt tcgcttgttc
    11221 caaatgggga tggttttctt caattactcc tacgctaaca aaagggtgat gttttacaca
    11281 gttgatctca ttgaaagtca tccaatattt tactttattt ttatagcgtt tgaatactgt
    11341 ttcagcgaaa cgaacgtaaa actgaataag ctttcgatta ggccatccac catattctgt
    11401 aaccaaatat aacggcattt cataatggga aagagaaacg actggctcaa tcccatattt
    11461 tagacattcg tcaaacactt gatcataaaa aaataatccc gcttcattgg gtgtttcttc
    11521 atcaccatga ggaaaaattc ttgtccatgc gatagacatc cgatagcatt taaaacccat
    11581 ttcagcaaat aaacggatgt cttctttaaa gtgatgatag aaatcatttc cgtgtctttt
    11641 aggataataa tacttgctgt tgggatcctg cgccgctttt acttgctgat gcgtcatcat
    11701 atgccattga tctgtccatt tttctttagg taaatcgctg tcgaatgtat acacatcaga
    11761 cacagataat cctttttcat ctacatccca tgcaccttca cattgattgg ccgctgtcgc
    11821 tccgccccat aaaaatcctt ctggaaattt tttcatatcg atccccctaa acttgctagt
    11881 tttcttgttt gattattttt cttatgacta gtaatgatat ttttgaatct actactattt
    11941 gtaacaataa ccattgtggt cggatcatat ccctctttga ttaattcttg caaatctact
    12001 tccatcaata aatcgccttt acgtactttt tttccatcag atactgcact ttgaaagtat
    12061 ttgccattta aattcactgt atcaataccg atatggatca gtatctctgc tccttcttca
    12121 ctgactaccc caattgcatg tttcgttgga aaaactgttg aaacttcccc gtttacagaa
    12181 ctgtagattt ttccgtccgt tggaatgatc gcaaaccctt ctcctaaaga tccactagca
    12241 aatgttggat cgtttacttc agataaatca attatttcac ctgctgcagg agtacttaac
    12301 actatatcct ttgaggattc ttcttcgatt tcatccttgt agccgaaaag aaaagttagc
    12361 atacaggaac tgatcatcgc taagaaataa ctagcaacta gccaaacaaa tccttcacca
    12421 atataaatcg ggaaagacaa aatacttctt gtagcaactg ccaaagcacc ggctcctgcg
    12481 gcaccagcta ctccaccaaa tatagctcca catatacaag caatgtaaaa tggtcgttta
    12541 tatttaagag tcacaccata aacagcaggt tcagtgattc caaataatgc tgtgataaat
    12601 gcagataaag ataaactttt tactttctta tttttcgttt tcaaaaatac cccaagtact
    12661 gctcctgctt gcgcagctac ggcagtcata catgctggac ctagcgtatc acgaccgtag
    12721 aaagaaagat tgttggtcat tactggtaca agtccccaat gtaacccaaa aatcactaac
    12781 acttgccaaa atccgccgat aacagcacca gataaaacag ggctaaagtt ataaacagct
    12841 aaatatccag ctgcaatcag ctgacttgca taatctgcaa ttggacctac aactaataaa
    12901 ataattggga ccatcacgat gatacaaatg aatggtgtca ataaatttcg aatactttcg
    12961 tgcaagcttt tgcgaatctt aggctcaata taagaaagaa cccatacagc taaaattgct
    13021 ggaataaccg tacttgtata ccttgctaga atcacgggca tccctagaaa tcgcaaggtt
    13081 atgctatcac tatatgcact gacaatcgta ggataaacga gagctgctgc aataaccata
    13141 gcgatgaaac gatctgtatt gaactttttt gcagcagtat atgccaaaaa tataggcaag
    13201 aaatagaaaa atgcatcagc tgctgcattc aaaatgatat aagttcctga ttcagtagtt
    13261 aataaattca aactcgtaca taaggcgagt actcctttga tcaaaccact tcctgccaag
    13321 acgcctaaag tcggggcaaa aacagcggcg atcatgtcta taaaagagtt taaaatgcct
    13381 tttttctcag ttcctctctt tccactagat gcatcatctt ctagtttcat ttgtttggat
    13441 aatacgtcat acacttcatt tactgcattt cctactacga cttgaaacat tcctccagct
    13501 tcgactacag tgatcacacc ttctagttgc tctaccttct ccttatctgc cttcttatta
    13561 tcttttaggg taaagcgtaa ccttgttgca caatggtaaa cattgctgac attttcttcg
    13621 cctccgacaa atcggacaat atctttcgct aattgtgaat agtccatttt tacttccccc
    13681 ttgttaatta atgccgtagc aatccttctt acaagataag tatagttctt agaaaacggt
    13741 ttctccattc aattagtacc ccttctaata gcgaacgaaa ctgtacaata gtgtgtatgg
    13801 tttacttagc cgagcaaatc actcactgct tgaaagaaaa caagtatatc gtttctctta
    13861 tagtcaaagg agacaaaaaa aacacgcttg atcttccttt gctgatgtat aagtggtatc
    13921 tcaagctgat actctgtgat ttttgtttct acttggcttt tgataagaca gcacaacaaa
    13981 gtctcggcat ttaacggaag cataactagg tcagaactag gagagattag ttgctgaatg
    14041 gaatctatct ttttatggat ttttatttga ttttcttctt tgtagtaatg atcaagcagt
    14101 tttgttttct ttttttcttc aactatggtc agcttttcac gcaaaatctg ataaatctcc
    14161 caagattcaa actcatctag aacactaggt agataaatca aatcatccca ctcaaaaata
    14221 agctcttgct cagtagtcaa aattgcatca tattccgtta ttttgtttga ttgatttttg
    14281 aaaagataca ctggttctat ccggcattct ttgatccaca tgttcatact ttgttgaatc
    14341 tgttttttta gtgtattcaa aatactaatt ggctggttac taacaatcag tatctcccct
    14401 tgttttcgaa aaggattcaa cgcttcggca agatacaaaa caaaataagc gctttcagct
    14461 aaattgggac gtaattgaaa atgtattggg aagaaacgcc gaattaaata aatttctaaa
    14521 ggataacggg agatgttctt ttgtacaaaa tgattcatgg tattatgtcc ggcatccatc
    14581 ctcgttttca tttgtttgat atgggttagc aaaaattctg tttcatggaa caataacgaa
    14641 acaggaagat ctaaaaaacg aataatcgtt tgctcaaatg ctcttagatt cttctctatt
    14701 tctttgtttt tttcatcatt aatcatcaaa taatttaact ctaatagtcg attttcaatt
    14761 gcttgttttt cttgattgga aaaagaatag ggtagttctg atgataactt ttttgtgagg
    14821 gtctctacca tcggaataaa taatgtatac ctgtttgttt tttctaaaag ttcttctctt
    14881 cgaagaatgg tcaaaacgag ataccgagaa aatcgtatga agtcctctcc tgaaacaata
    14941 taattatatg atataagaac ctcttttaat gtcttttgga cagtcggcat gatattggaa
    15001 aaaattgtac tgatttgttg aggaaacctt gcgtgttgga tcaccgtttc tgttccaaca
    15061 agagataaga aaattctttt tgaattttct tcagcaatga tttttagtcc ttttgtcgac
    15121 gaaacttcca gttctaattt aggattgcgc tcgatccaac gcaaaatcgt ttttatttgt
    15181 aatgatacgg ctgtttttga aagaaagaaa atgtctgcta tcttttgcat actgacatac
    15241 cctttttgaa acaataagta cgtcacaata gttgaagctc ggaaatccat gctggaatag
    15301 attttatgtt tcgtcacctc ttgtatgatt tgctgtttag tttcagattc aattgattct
    15361 aaaaaataac ctgaacgttt atttgactgg ataatgattt tcttctcgta gatagcaagc
    15421 atatttttga tttcagtttg gatcgttttc ttgttggtac ctaaagcttc agctaattct
    15481 tcgcttgtta tccaatgatt cttatttctt aatactacaa gaatttggag ttgtcgttta
    15541 tttaagtcca tttgcttaca cctcctcttt gttataaaca tacaggaaaa acctctcaaa
    15601 tgacaatagt cacttgcaga ggtttaaaaa tcatttgaag aaagatctat attcaaggtt
    15661 tttaccatta gactggataa tttgtttata atattcaaaa ctatcttttt tcaatctcct
    15721 aaagcttccg ctcccatcat tttgtctatc cacataaata aagccatatc gcttcctcat
    15781 ttcccctgtt cctgccgata cgatatcgat tggtccccac cataagtaac caatgatttg
    15841 gcaaccatct tttattgcct cagcaatttc ctgaagatgt atttttagat actcacaacg
    15901 ttttggatcg tggattcgat tcaattcatc tggtgcttca tctagtccaa tgccattttc
    15961 aactatgaat aatggtaatt cataacggtc tgtcaattca ttcatgacat aacgaaaccc
    16021 tagaggatca attggccaac tccaaggttc gggagatttt tccttcaaaa agggattatc
    16081 gaaaccattt gctccgccag tatctacgcg catttctgct tcttttttat agacagcgct
    16141 acgataataa ctaaatgcaa tataatctgc cgtgttagct tgcaagcact gttcgtctcc
    16201 atctaacatt actggtgcac agtcttcttc cttccatgtc ctgtaaatat aagctggata
    16261 atgccctcgg cacatgacat cggagaaaaa ccatgaattg cgtttaaatt gcagtgaacc
    16321 aaatacattc tctggatcac agtcatatgc ataagtcgct aatgcagaaa agctacacat
    16381 aatacccatc ttagcatttg gatcgatttt ctttaataat tgagtagcac gggcgttcgc
    16441 tagaaacata tgatgacagg cttgataaat cacttttttt gttagtgtag caatgggttc
    16501 aagtttatct ctagcaggga atgtaaccaa tccagcagct gcataaggca tacgaaaagc
    16561 attattgatc tcattaaagg tcatccaata tttcactttc ccttggtagc gttcaaagac
    16621 ggtctgcgca taaaattcaa aaaagtcgat taattttcga ttttgccacc ccccatactc
    16681 tcctaccaat gctaaggggg tttcataatg actaagagta attactggct cgatatcata
    16741 tcgatttaat gtattgatta gtctgtcata aaatacgaga ccagcctcat ttggcttctg
    16801 ttcgtctcct cttggaaata ttcgtgccca tgagatgctt gttcgaaaag cttttaaacc
    16861 taactccttc agtaaacgaa tatcctcttc aaatcgatga taaaaatcaa tcgcttcatg
    16921 agaaagataa tggagtgatt cgtctaaagc aatctcccaa atcttttttt cttcattcca
    16981 ctgaatacta ggatgctggt tcatgatccc gataagcgta tctgtcacat taggtaattt
    17041 gccgtcttcc aaccatgcac cttcacattg attagcagct actgctccgc cccataaaaa
    17101 attttctgga aatatttcct gatccataac tatctctcct cgctatcaac aatttcttac
    17161 ttgaagtata gctcgattca tcaaaacaag atattctaac tatttcggca gaagagaaga
    17221 aaaaaattga atgctactct tcatttttaa tatttatata taacaaatac ataagacgat
    17281 ccccgaaaga aaacactcgt taaccatcta agcaaacgat ttattttact tccaacacaa
    17341 atgcttcata aggtcgtaaa tcaactttgc cgtctggtaa ctgtttcaga ggataatttg
    17401 acacaataac ccttaaagct tcacgtggaa tagtgaacgt ctgcttttca ctggacatat
    17461 tacaaataac gagccattgc tggtcttcat atatgcgaga ataggcaaag acatgctcag
    17521 gcgtcttttc cactaattca tagtctcccc agacgatgat gtcatgtttt ctacgcaaat
    17581 cgatcaattt cttgtacata taaaaaacag aatcttgatc tgctaacgct tcttctgcat
    17641 tgatttcttt ataatttgga ttgactcgaa gccatggaat tccagtagta aacccagcat
    17701 gttcacgggc gttccattgc ataggcgtcc tagcattgtc tcttcctttc gccttgattg
    17761 attccaagat ttcctctttt gtaaatccag aagaaatcct ttcgttatac atattgattg
    17821 tctcaatatc ttttgcttcc gcgatatcat cgattgggca attcgtcatg cctaactctt
    17881 ctccttgata gatataaggg gtgcctttca tcatatggag caagatagca aacatcttgg
    17941 cactttcttt tcgatacaca tcgtcatttc cccaacgaga aacaattcgc ggaagatcgt
    18001 gattattcca aaataaacta ttccatcctt catcacctaa agatgtttgc catttggata
    18061 atactttttt cagttcagag atactcaagg gtttcaaatc ccatttgtct ttgccttctt
    18121 gctgatctaa tcctatgtgt tcgaattgga agaccatgga taattcattt cttttaggat
    18181 tggaataaag tttagcgatt tcggtagttg ctccccatgt ttcgccaaca gtcatcagat
    18241 ttttgtcacc aaaagttgct tgattcattt cctgaagata ctcatgcagt ttaggtccat
    18301 tacttgtgat ttctttatcc ggttctttgc caatcatatc gatcacgtcc atacgaaagc
    18361 ccccaatacc tttatcgatc cagaaattca tcatttgata aatctcttgg cgaacctgtt
    18421 tatttttcca attcaaatca ggttgacgct tgctatacaa gtgcagaaaa tattgccccg
    18481 ttttttcatc caactgccaa gcagaaccac tgaatattga gcgcaatcta ttaggctctt
    18541 ttccattgac cggatcacgc caaatataat agtcccgata aggattttct ttatttttac
    18601 gggcctcaat gaaccacgga tgttcatcag aagtatgatt caccaccaga tccatgatga
    18661 tacggatatt tcttttcttt gcttcttcaa tcagttcttc catttcttcc atcgtaccga
    18721 attctgccat gattgcttga taattactga tatcataccc attgtcatca ttcggagact
    18781 cgtatactgg agaaagccaa attgcatcaa tacctaaata cgccagataa tccaacctgg
    18841 aaataatccc ccgcaaatct ccaataccat cttgatttga atcttgaaaa cttcttggat
    18901 agatttgata aacaactgaa tggtgccacc atttttgttc catgattttc ctcctataaa
    18961 tggatgtttc tattttttgc ttaatcattt attttagtct ctctcactaa aaattgtaac
    19021 gctttcaaat agctattgca ccttgttatc ggtaacagaa taaaacaaaa aaacagctga
    19081 ggaaattccc tcaactgttt tttgaaagga ttgatttatg cagggaagaa tgctgatttc
    19141 acaacttctt tataaacggt gttcactcag ctgtcccttg gtattagctc aaaaaacggc
    19201 aaaatataag aaactatttt ttcgtttttt tctctaatac tcaggccaga acgctgattt
    19261 cacaacctct ttatttcaca ttcaatatcc acatgaatcc cacaaataca aagaacagac
    19321 catacatgat tggagatact tcttttcctc ttttagctgc taacatggta attggataga
    19381 agataaaacc taatgcaatc ccatctgaaa tactataagt caaaggcatg ccgatcaaga
    19441 tcaagaatga agggatcgca atctctaagt ttccccattc gatttgtcgc aaagattgtg
    19501 ccatcaatac tcctaccata atcaatgctg gtgcagttac ttgtgaagta acaactgata
    19561 gtaatggaga aaagaacaag cctaacaaga agaaaatccc tgtagtaata gctgtgatac
    19621 ctgaacgtcc tccaacggcg ataccagctg atgattctac aaatgcacca acaggagaag
    19681 taccaaataa ggaacccgca agcatagctg ttgaatcaga agctaaagct ttccctacac
    19741 gaggcatctt gttgtctttc atgaaacctg cttggtttgc taatccaact aaagttcctg
    19801 ctgtatcaaa gaaagtcaca agcaagaatg tcagcactac gacccacatt tgaagagaat
    19861 tgatgtcccc tacatgtttt aatgcaacta aaaatgttgg tttcaaactt ggtgctgcgg
    19921 caacaatttc agaaggcatt ggaatcaaac ctgtgaccag acctaaaatc gttgtagctg
    19981 ccatcccgat gaagatgcca cctggtacac gccgaacaag caagatagca gttacgacta
    20041 atccaaaaat cgtcaaccaa gtagaaccaa cgttgagtga tcctaatcct actaatgtag
    20101 attcattcga aacgatgatc ccaccttcgc tcagaccaag gaaagcgata aatagaccga
    20161 taccgccaga aatcgcatat ttcaaatctg ctgggatcgc atcaatgatc atttcccgca
    20221 gcttgaagat tgtgatcaaa ataaaaatca aagaagcaac gaatacgccg gctaatgctg
    20281 tttcccatgg aatccccatt cctaaacaaa cagaataagc aaaaaaagca ttgatcccaa
    20341 gagcaggtgc cgttccaatt ggataacggg ctaatacccc cattaaaaca cagccgatcg
    20401 cactggctaa tgcagtcgca gtaaacactg ctccttcatc cattccagaa gcacctaata
    20461 cagttggatt tacaaataag atataagcca ttgagataaa tgttgtaaat cctgccagta
    20521 cctcacgttt taccgtggtg ttcaattttt ctatttcgaa gtaggaaagt attttttcct
    20581 tcatcttcca tccccctaaa tccgaacatt ataaataaag tccgttaaaa tttcgattta
    20641 ttaataaaac aacgtgtttt atcatatact aaaacaaaac ataagtaaac aaaaaattcg
    20701 gattttaagc aaaatccgaa cgttccatct gattaaatcc ctttatctca aagttcatga
    20761 acattcactt tggattacaa gaatttcttt attgtgttaa taaagtttct tcattctagt
    20821 ctcaaaaatc aatagtgtga tttgatttta ccatttcgtt tctgttcttc tttgatgaat
    20881 tcttttgtat cgacaggatt cagattattt agtccgccaa aacctgtatc gaccattttt
    20941 ccccagcctt ttgtcttctt ttttcctgat ttgagattct ttgctcgaag cttctcacta
    21001 tgttttgctc gccgatactt caaataacct tctaatcttc ccattagatc cactgttttt
    21061 cctccttttt attcaatcag acgactcagc ttttcctata acaaaataat tgccttcagg
    21121 gtcagaaaaa ttgaaagtca agatgccatt gttatctgtg atttctcctg gttcttccat
    21181 gttctcgtag atagtttcaa attcatccgt aaaaaatact aaagaaggcg gtggtcctaa
    21241 tacctctggt gaaaacttct gcacaaatac ttttgggaat acgcctaatt ctaattcttt
    21301 tgagatgctg agtacaatac tcttaaattc ttctggcaat tcgattgttt cagaaatttc
    21361 tgcaccaatt ttttctacaa agaatcggca aatcatctct acgtcattga cataaagcat
    21421 cacacgtgtt ttttgtatca tcatttgacc cttctttcta tttgattttc tttcctgtct
    21481 ataaactgat tccattatat cacgaaagcg caaacacctt gtgtttgata ctattcaaga
    21541 aaaataaagc aatagtttct aggattgctt tcctccacaa acttttttta caaaaaaaaa
    21601 acggcaatga atgccgctct tcttatttcg attcttttat aattctgctt ctgattcatc
    21661 tttggttagt gtgtgtctaa cactagttac gccaaatgtt tgatcgattt tttccttcaa
    21721 cgcttcgatt gcctgtgcgc cacgtgccgc ttgttcagca ttgatggatt caatgaccag
    21781 caccgctgct tgtgtttctt ccgtcagcat cgttctttgg gcttcacgcc agttgagaca
    21841 gcgacagatc gctccttgtt catcatagta gatgatttct tccggaagtg ccggagcatc
    21901 ggaatctgca cctaaaggca ggaatgattc gccaccttgg gcttttccta aatgcagatt
    21961 tcctgcgatc ttttcgatat cttctccgcc gcaaggtacg ccaaaagaca aggaaatact
    22021 attatagata tctacaagcg gattgattgg gaaaaattcc cgttcttgat ttgcacgttt
    22081 cagtaaagct tcaatagaag aacgtgcacc ttttttagtc ttgaatgtgg taaatgcctg
    22141 acgccactga gcaatgactt cgttttggct gaatgtttct tctgtaaggt aatttcttgc
    22201 ttcttttgct gcctcattca ataattgatg atacgtttct tcactttctt ttgttacgtg
    22261 gttatcgata ccatttacgg ataagatttc gatggttgct tcaggaaata cttcccagaa
    22321 attggtatcc actattactt ttttcatctg ttcacacctc ttgattagaa taattgcttg
    22381 atgaatagat agtctgtttg gggatcatct cccatataaa aaacatgttc gctgtatttg
    22441 ataaatcctt ttttacgata aaaagcgagc gcaacatcgt tgtgttccca aacaccgagc
    22501 caaatggctg ttttttgctt ttcttttgct ttttcaatag ctgtatctag taaaaatgta
    22561 ccgatacctt gatgtttaaa tttttttcgt acatagattc gctcgatttc taaaaaatga
    22621 tcagccattt cctcagattg actcgttcct gtatttagtt tcaggtaacc cgcaggctct
    22681 tgatcgatac tcactaggaa aaaatcggtt tctttatctt ttagctcttc tgtaagtttt
    22741 tctagtgcat aagcttgtgt caagtaatca gctaaatgct ccggtgaatt atcttttcca
    22801 aatgtatctg taaatgtttc gatactaatt tgttgtagta agtctacatc tgaaggcgtc
    22861 atttttcgaa tttcgtattt attcacggct tcttcctttc aatagatcct tttattgcct
    22921 tttttgacaa aattccaatc ttcgctaaca ttcttgcata ctttatttaa aagatattcc
    22981 aattgttttg cttcttcgtc agaaagacca tttaatgcga ctgcattgga gtagttgttt
    23041 tctcgaatga tgaaaggata gatttctgct ccttttttag tcggatagag tttcttgatt
    23101 tttttatttt ctttatcttc caaacgttcg atcatcccat tggattctaa tttcttgatt
    23161 gctcgggcag tcgttgtacg atctactttg atcatttctg ctagtttttc ttggatgatt
    23221 ccaggatttt cgcaaatacg tactaaataa agatactgtc ctcttgttaa atcgacttct
    23281 ttgaattcga tattgctaat agaatctagc gctcgggcaa tcattccgat gtctcgaagg
    23341 atttcagcca tttcatccca cctttatttt gtttgtaaga ctagttcacc tctttttgtt
    23401 gcaaatgcaa ctattttcaa taaaaaaatc aagttctttt ttaataacta gtaaagtata
    23461 ttcttttctt cttttacgaa aaagctcaat cacaatagat ctggtttttg ttttctaaaa
    23521 taagtaactg tttcttcgtt gttcgctttt ctgatagctt tggcaactct tctatactaa
    23581 aaaatcccat gttggaagtt tcattattct caataaactt ggcctcttca ccgtggatcg
    23641 cacaagcaaa aacaagttta taatactgaa aaagctgtgg aatatctttt tgtttattcg
    23701 tatcaaaaac tgctcgcaac tgagtagttt ctactgttaa tcctgtttct tcatagactt
    23761 ctttacgcac attttcttca ggagacaatc ctatttcagc aaatccacca ggaagtgacc
    23821 attctttcgt ccgtttatct tcgattagta ggaccttgcc atcttttttg atataggcac
    23881 gaacatctac ttttggtgtt ggatgtcctt ctccaatcgt tgtgagcgct tttatttctt
    23941 cgaaagtttc ttttcctatt tcactgatca gttccaatga aatcgtccgg atctcctcaa
    24001 aacgctcttt atcaaataca tcttttccat aatatagacc agcttgagaa agtgcgagta
    24061 gtcttttgta ttgagccaac ttcttgttca ttctcttccc ttctttttta gcaaatgtat
    24121 gactatgtaa tcaagtatag aagactggtt taattacggc aaataaatat aatgaaatct
    24181 gcaataaata aaagaatgtt aaaaaactcg agaacaaaag acattcgact tctctggggc
    24241 tgtgaataaa tggcgttcaa aagcttgcat ctgcggtaat aagccccacc aaacgaaaaa
    24301 tatgacgagc tattcttgtc tggctgttct tattaattga ggcaggacag ctttttcaca
    24361 acctccccac taaacggtgt tctcctacca actcctcggt cacaagtcac aatattcatc
    24421 aaacatgaga agctgttttt ttgaaattgc tccttgtgac tcggagctga acgacaggct
    24481 cacgacctct cggtaaacag cgttcaaaag ccaatttttc gatattaagc catttctttg
    24541 ttacttattg tcattgattt ctttttctaa tttatccaat agtggagtgt aatccacttg
    24601 agtatagtct gttacatcaa attcatatag tgttcctaac tggaatttgt catattttcg
    24661 gtcggcgatg atctttttga atgcttcttt cgtaatatga ttggtccctt tcgttcgatc
    24721 ttccaatacg tcaccatagt gataatgatc catgatatag ctcaaatgac gatctgattc
    24781 acgatcacgt ttgtaccgac gttgccataa cacttcaaag tctgctgtta ggcgaatcgt
    24841 gatcacctga tatccgtatc tatctgctaa ttcttggagt cgtgcttttt gcttatcact
    24901 aaaaggatac tcggacacaa tcactttctt tcctgcttcc atatacaaat caagtgcttt
    24961 gtaatagaaa ggataaactt tcgtcctttc ttgttccgcc cgttcttcca aattgttaaa
    25021 cccgatggat tctgcatagt attccttgat ttcatcgagc gtgatggcat acatatctgg
    25081 aaatcgttcc cgtagtttat tcataagata tgtttttcct gtaccaggac taccagccag
    25141 aagaatgaaa tactttttca tctcatttat ttcctaagtt aattggactt tccaagttca
    25201 taaacagtcc aatcttatgc ttgacaattt cttttactgc ttcatttgct ggaatcacat
    25261 tatggcgaag agacttgttg atttctgttt cactaaaggt ttctttagct actttcgtcc
    25321 agttgactaa aagctccgtt ccaacattga atttgcggat cccgttattg atcaattcag
    25381 gataatcttc ttctttcaca cctgttcctc catggataac tagggggaca tcaactactg
    25441 catcgatttc tttcagcaag ggaatgttta cttctgtttt tgatttgaat tgtccatgat
    25501 tcgtaccgat agcaatagct aatgcatcca cgcctgtagc ttctacaaat ttcactgcgt
    25561 cttccggtct tgtatatacc ttgtcatttt cagcgacatg gattccttct tctgtaccgc
    25621 cgattgttcc aagttctcct tctacggaaa caccgtgcgc atgggcatat tctactactg
    25681 cttttgtctt caggatattt tctttgaaag gcagatggga cccatcatac atgacagaag
    25741 tatatccgct gtcgattgct tctttgatat catcaaagtc tcgggcgtgg tctaagtgca
    25801 agactgcatc aaccatttct tcttctgcaa tagctgtcat tacattgact aacacatgca
    25861 tgccgatata tttagcggta tcgacacttg tttgaataat gatcggcgaa cccatttctt
    25921 ttgctgcgcc tagcatagca ggaagcattt ctaggttatg cgtattaaaa gctccaactg
    25981 taaaattcaa ctcttctgct gtttttgtta cttctttcaa tgttgtatac atcttttatt
    26041 gccaccttat ctttttattt gtttcctttg atcgttactt gttttgcaat ttgtcgcatc
    26101 tcatccattt tgcccatgta gtaatcgatc ccttgatcat caccagcacg agcagcatct
    26161 gcacgcttct ggttatagag gctcatcagt tttttatacc catctccgat cgtctgttta
    26221 ttttccaaac tcttttctaa atattggatg gcttgatcgt tcacatacaa ttcagaaaat
    26281 ttaagtccaa cttgttcata aagtttcgct aatttatgct tatcttgggt agtggaaatc
    26341 tcttgtttca attgtgtaat ctctgattga atcttttcgg tcgcttctgg cgatagggct
    26401 ttttcttctt ttgccagaac ttttttcggt tctttttctt ttttcttaaa aaatccaaac
    26461 atcattttcc ctactttcaa ttaaaatgct ttcaaaactg ggcttaagat ccaggcatat
    26521 aagagtgctg cggctactgt atctacatcg gttgctgtag cattgttgaa tcccatcgaa
    26581 ttaaagatcg ttactagcaa agcgggcaat aatgtaataa agaaaccatg agcaataccg
    26641 ccaatgatcg ctcctcggcg tccgccaact gcgttgccaa atatccctgc tgtccctccg
    26701 gcaaagaaat tggttagcat accaggtaaa atcatcgcta agccgaacat gggcaaagta
    26761 aacatggcaa taatcgtacc aatcgttgtc gtaatgaaac ctaaaatgac agcatttggg
    26821 ctataaggaa agaaaactgg acaatctaag gcagggatcg catcaggaac taatttcata
    26881 gctatccctc gaaatgccgg cacgatttca cctaacagta gacgtacacc agctagcaat
    26941 acatacacac ccactacgaa ttggatggct tgtaaaaagg caaacatgat atagttttga
    27001 tctcctgata attcagaagc gaatggttcg cctgcaaata aaacagtgat gatatatagc
    27061 gggaccatca cgaccatgac agacaaataa gtatcttgca gaaattcgaa atgtgtcggc
    27121 aacttgatat cttcgatcga ctttttattt tcgcctttct caccaaaaag cttagcaaca
    27181 ccggcttcaa ataagtaccc gatcgtacaa aaatgaccta aagcaatatc atttgatcca
    27241 gtgattttac gaatgatcgg ttgcgctact gccggcatag caatggcgaa acaagctccg
    27301 ataaaaccac cgaccaagat caatacgatc cctcgcagac cggcaaaata gccaaagact
    27361 gtcgtcatcg ttgccatcca taaaattgct tgaccagtta aaaaaatgta cttccatttt
    27421 gtgaaacgag ccaaaataat attgaataca aaaatggcta agaacgtcag tgcaatatct
    27481 ctacctaaac ccaaatcatt cattgcttga ccattgatag attcaataga agggatgatc
    27541 ccttgcatat gaaatccttc agtaaagatt ttcccgaaat aagttaaact tccaacgatg
    27601 atgctcgaac cggcactcaa cacttgaaat cctaggagtg tctttaacgt gccagagatg
    27661 acttgtcctg ctgatttctt ctgcagtagt agacccaaca tagcaatcaa tgcaatggtg
    27721 atcgatgcct gagtcaaaat attttcgatg ataaaattga taacgcccat g
//
LOCUS       DAPBAF010000039        27531 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.039, whole genome shotgun sequence.
ACCESSION   DAPBAF010000039 DAPBAF010000000
VERSION     DAPBAF010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 27531)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27531)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27531
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.039"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(45..1511)
                     /locus_tag="RD451_001990"
     CDS             complement(45..1511)
                     /locus_tag="RD451_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HDT7567227.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
     gene            1898..2494
                     /locus_tag="RD451_001991"
     CDS             1898..2494
                     /locus_tag="RD451_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDT7567228.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAGEKEYMNDADRFRVFG"
     gene            complement(2552..3034)
                     /locus_tag="RD451_001992"
     CDS             complement(2552..3034)
                     /locus_tag="RD451_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567229.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(3140..3337)
                     /locus_tag="RD451_001993"
     CDS             complement(3140..3337)
                     /locus_tag="RD451_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567230.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            3632..4390
                     /locus_tag="RD451_001994"
     CDS             3632..4390
                     /locus_tag="RD451_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HDT7567231.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
     gene            4450..4878
                     /locus_tag="RD451_001995"
     CDS             4450..4878
                     /locus_tag="RD451_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567232.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            4924..4996
                     /locus_tag="RD451_001996"
     tRNA            4924..4996
                     /locus_tag="RD451_001996"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4957..4959,aa:Gln,seq:ctg)
     gene            complement(5146..5517)
                     /locus_tag="RD451_001997"
     CDS             complement(5146..5517)
                     /locus_tag="RD451_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HDT7567233.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            5732..5917
                     /locus_tag="RD451_001998"
     CDS             5732..5917
                     /locus_tag="RD451_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567234.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            complement(6000..6188)
                     /locus_tag="RD451_001999"
     CDS             complement(6000..6188)
                     /locus_tag="RD451_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567235.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(6212..6475)
                     /locus_tag="RD451_002000"
     CDS             complement(6212..6475)
                     /locus_tag="RD451_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567236.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            6633..6890
                     /locus_tag="RD451_002001"
     CDS             6633..6890
                     /locus_tag="RD451_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HDT7567237.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            complement(6961..7152)
                     /locus_tag="RD451_002002"
     CDS             complement(6961..7152)
                     /locus_tag="RD451_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567238.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(7293..7613)
                     /locus_tag="RD451_002003"
     CDS             complement(7293..7613)
                     /locus_tag="RD451_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567239.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            complement(7636..8070)
                     /locus_tag="RD451_002004"
     CDS             complement(7636..8070)
                     /locus_tag="RD451_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HDT7567240.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            8405..9043
                     /locus_tag="RD451_002005"
     CDS             8405..9043
                     /locus_tag="RD451_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HDT7567241.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNSISDINLIYSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPV
                     QAEQPVVQETVQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTAT
                     NGRYIGRYQLDSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            complement(9367..9450)
                     /locus_tag="RD451_002006"
     tRNA            complement(9367..9450)
                     /locus_tag="RD451_002006"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9414..9416),aa:Leu,seq:cag)
     gene            9978..10478
                     /locus_tag="RD451_002007"
     CDS             9978..10478
                     /locus_tag="RD451_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7567242.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            complement(10668..11012)
                     /locus_tag="RD451_002008"
     CDS             complement(10668..11012)
                     /locus_tag="RD451_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HDT7567243.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(11166..12086)
                     /locus_tag="RD451_002009"
     CDS             complement(11166..12086)
                     /locus_tag="RD451_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDT7567244.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            12273..12764
                     /locus_tag="RD451_002010"
     CDS             12273..12764
                     /locus_tag="RD451_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HDT7567245.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            complement(12788..15163)
                     /locus_tag="RD451_002011"
     CDS             complement(12788..15163)
                     /locus_tag="RD451_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HDT7567246.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            15489..16115
                     /locus_tag="RD451_002012"
     CDS             15489..16115
                     /locus_tag="RD451_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDT7567247.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            16138..16842
                     /locus_tag="RD451_002013"
     CDS             16138..16842
                     /locus_tag="RD451_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HDT7567248.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            17034..17867
                     /locus_tag="RD451_002014"
     CDS             17034..17867
                     /locus_tag="RD451_002014"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HDT7567249.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            18064..19992
                     /locus_tag="RD451_002015"
     CDS             18064..19992
                     /locus_tag="RD451_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HDT7567250.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            20130..20585
                     /locus_tag="RD451_002016"
     CDS             20130..20585
                     /locus_tag="RD451_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HDT7567251.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            21055..21324
                     /locus_tag="RD451_002017"
     CDS             21055..21324
                     /locus_tag="RD451_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567252.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            21724..21978
                     /locus_tag="RD451_002018"
     CDS             21724..21978
                     /locus_tag="RD451_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HDT7567253.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(22067..23113)
                     /gene="holA"
                     /locus_tag="RD451_002019"
     CDS             complement(22067..23113)
                     /gene="holA"
                     /locus_tag="RD451_002019"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HDT7567254.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(23151..25424)
                     /locus_tag="RD451_002020"
     CDS             complement(23151..25424)
                     /locus_tag="RD451_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HDT7567255.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRLSGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            complement(25417..25956)
                     /locus_tag="RD451_002021"
     CDS             complement(25417..25956)
                     /locus_tag="RD451_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HDT7567256.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            complement(26092..26310)
                     /locus_tag="RD451_002022"
     CDS             complement(26092..26310)
                     /locus_tag="RD451_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HDT7567257.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            complement(26307..26552)
                     /locus_tag="RD451_002023"
     CDS             complement(26307..26552)
                     /locus_tag="RD451_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HDT7567258.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            complement(26668..27396)
                     /locus_tag="RD451_002024"
     CDS             complement(26668..27396)
                     /locus_tag="RD451_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HDT7567259.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
BASE COUNT         8536 a         5358 c         4694 g         8943 t
ORIGIN      
        1 aggaactgct gcaaataagc aattcctgtt tttatgttca ttgattaatg aatagagccc
       61 attagttttt tgattggttc tttcacagta aatagcaaga taccaccgac gattgctact
      121 gcaccgataa taccgaagta agcagattct gttcccggtg tgtagaagcg tgcaatttgt
      181 gcattgattg cttgtgaaga agcatcagct aagaaccaaa tagcgattgt ttgtgattca
      241 aatgctcgtg gtgctaattt tgttgtcaca gacaaaccaa ctggtgaaag acacaattca
      301 gcaataacca cgatgaagaa acttcccaac aaccacaatg gacttacttt tccacttgta
      361 ccataaagca tacccggcaa catcaatagc aagtacgata atcctgcaaa taaaagtcca
      421 agagagaatt tcactactgt agatggttga cgttcaccaa gtttcgtcca catcgttacg
      481 aatactggtg tcagaataaa gatgaaaatt ggattcaatg attgatacca gcttgcttgg
      541 atcgttacac caaatagcgt agattgtgta cgttcactag caaataaagc taagatagat
      601 gaaccttgtt cttgtaatga ccagaaaatg attgctgcaa ggaataatgg gatataagcc
      661 catactcttg gtttttcttc agcagttaca tcttttgaag tcagcatttt gataaagtaa
      721 tacaacggta agataatccc caatacactg attgtattga caaaaaagtc aattgtcaga
      781 tgaccagtta gttgtgcccc gccgaatact gcagcgataa caacaagtgc gatgatcaag
      841 ttacggatga atcctttacg ttcttcagtt gtcaaaggat tcggcggtgt tgtacccact
      901 ccgtctaatg tcttgcgtcc ttggatgatg tattgtaata atccaaagaa catcccaata
      961 gcagctaaag agaaccctaa atgatagtta tattcttgac cgattgtacc aacgattagt
     1021 ggtgctaata atgcccctaa gttgacaccc atgtaaaaaa tcgaaaatcc tgcatctctt
     1081 cgcaagtcag tctttgaata aagatgtccg accatgccag aaacatttgg tttcaaaaag
     1141 gcggttccga taataatcaa tgccatcgaa acaaacaatg tacttacacc aaatggtaaa
     1201 gccaagacga tgtggccaag cataatgaaa actccaccga agaatacagt gcgttttgct
     1261 cctaacactc ggtcagatac ccatccgccg acgatactag acatgtagat caaagatccg
     1321 tagatcgaca tgatagctaa tgctgttgct cgtggtaatc caagtccccc gttggcaact
     1381 gtatcgtaca tataatagat aagtaatgca cgcataccgt aataactaaa tcgttcccac
     1441 atctcagtga agaacaaagt tgacaatccc ttcggctgcc cgaagaagcc cttgtcttgc
     1501 tgtttttcca taatctatac cccaattctt taaattttca gaaaatatta tacatcttta
     1561 ccgaaaaatt taactaaaaa acttatttaa gaaatataaa ctaattttct ataaaagcaa
     1621 gtaattttta atggcaatat cataaaaaaa agaagataga gatttaataa ttatatatca
     1681 gctgtttttt tcaaataagc aaaaattcct aaaacacaac aatgaaagcg ataactaaga
     1741 aaatccttac ataacgattt ttcttattaa aattgttttt tgaacttcgc ttattttttg
     1801 tgagcatatc tgtttactta ctttttgtaa ggtgctatac ttcatttcgt aatcaattaa
     1861 aaaaatgcaa aacgcaaatc aaaggagaaa ttttattatg acaactttta ctgacacttt
     1921 gaaaaaccgc cgttcaatct atcatctagg acgtaatgtt tcactttcta atgaagaatt
     1981 aacaactttg atcaaagaag caattaaaga aagcccaact gctttcaatg ctcaatcaac
     2041 acgcgcagtt atccttttcg gagatgcaca tgaaaaactt tgggaaatca ctgaagaagc
     2101 acttcgccca ttgactccag cagaagcttt cccaaataca caaaacaaat tagctggttt
     2161 caaaaatggt tatggtacag tattattctt caaagatact gacgtggtaa aaggtctaca
     2221 agaacaattt gaattatatg cagacaactt cccagattgg tcagaacaat caaacggaat
     2281 cgcaacagct aatacttggg tagcattagt tgataaagga ttgggcgcaa acttgcaaca
     2341 ttacaaccca gttattgacg aagcagttgc aaaagaatgg aatatccctt caaactggaa
     2401 actacgttcg caattagtat tcggttcacc agaaacaccg gctggggaaa aagaatacat
     2461 gaacgatgcc gatcgcttcc gcgtatttgg ataattttat ttgaaataaa aaacagaggt
     2521 tgtgacaaac atcttgtcgc aacctctgtt tttattctgg atcaatcata atatcaatct
     2581 ctgcctcatc gtttaagcgt tgggacaaaa atggaactaa ttcttctaat gatgcagaaa
     2641 atttcagcat cggtcctcgc catccgtttc ggaaaaaatt catttttacg attttagaac
     2701 cttttggctg atataataca attttattga tctcagaaaa aggaacacct tttttgtcaa
     2761 agctattcaa aacaagtcct tcttctgtga ttcctctact gtccaacaaa aaactaataa
     2821 aaatcattgc tgacaagatc ccttttgcca attcatctgc tgtaggatga ctgatgagtg
     2881 tataccaaat gactagtgac actaagaagg gtatcaccaa gtagacccat cgatttcgca
     2941 cagtccgata aataatttct tttcgaacca gccaaagaaa taaaaacatc acaacaacga
     3001 ataaaaacaa tagaaccgta aagaatgtta ccatgacaac tcgcctcgct ttttcttctc
     3061 cagaaaatag gaaaagaata ctgatttacc ttctcaaaga aattggactt gcagcacgcc
     3121 gcacgtccaa ttgttttctt tattcaaatg tatcatattt tgcaacaacc atgcttgctt
     3181 tttcatctaa taattcttgg tcctctgcag cacattgggc aactttgacc acggcgcagt
     3241 ttgtcatttt tgatacaact tcaccaatga ccgtttttgt aaaaccaatt ggtttgcatg
     3301 catattgttc tcctaaatta atcatttctt ccgtcatcaa aatcctccta aactgctgga
     3361 acttttctcc acattaccac tgctatttct ttggagattt aactcattga tttttattta
     3421 cagttaaaaa tcaaccttac aggcattata gcgtactgtt ttcgttttca caattaaaac
     3481 agctgttgta tttagaagaa tttttttcaa aaaattaaaa catattcctt aaaaactaat
     3541 tatttcctac atattaaaat ataatacttc catttccaat aaaaatacat ttataatagg
     3601 aaagataaac agctgaaaag ggagatttca aatgaagaaa aaaacgttca aaaaactatt
     3661 gtttctaggg ggcacagctg ctcttttatt aagcggtaca agttattacc tacatatcca
     3721 ttctccagaa catacaatga acactgcaca aaaaagttca acacaaaaaa cgaaaaagac
     3781 aaaagagaaa gcagaagttt tactagatgt tccattagag agccagtttg attctccttc
     3841 tttagaaaat ggctgtgaag tcacttcgct ttctatgctt ttatcttttt atggttatga
     3901 aacaactaaa aaccagttag ctgagcaatt ggattacgtc cctgttttca atgcagatgg
     3961 gactcatggc gatcctaatg aaggatttgt tggtgatatc agtggcggag actgggctat
     4021 ggtcgtctat gttcccccag ttgcctccct tgctcagcaa atcgtccaaa cggattatca
     4081 cacttttcca aaaaccgatg ctcaactcga tgatatcaaa aaagcactat ctaaaggaaa
     4141 tcctgtctgg acttctgtga ctatcaattt tgaagtccca gatgaaactg attttatgac
     4201 ttggaccaca aataatggag aagtaagagt cactcctctt gttcatgctt gtgtagtcac
     4261 tggatatgac aaagaaaata tttatgtcaa cgatccctat ggtgtaaaaa atcgagcagt
     4321 accgatcaac gatttttcgg cgattttcac tgcaatgggt ggacagatgc taactttgga
     4381 gaaaagctag taattcaaac aaaaatccct tatactcaag ataccaaacc tttgaaggga
     4441 gcgtagataa tggaaaaatt cacacataaa aaaatggatc caaatgaaat tccgattatt
     4501 tttgtccgtg actgcaaggg aaatgttcaa ggtaaagtct ctattaatga gtggaacgag
     4561 cgtcgcagac ctgctaccct caatgaactg gaaatcaaat tgtatcgtca atctcttgtt
     4621 tattacgcag atcaagagta cgagaaagcc accgatttat tgaaatttct aattgctcga
     4681 acagagtata ctcgctttga atatattgaa cgtttagcaa acatctatca tattatgaat
     4741 gaacctgtca aagaatatca gttattggac accgtcttgt cagtagcaga actgattgcc
     4801 cttcctgctg gattagaaaa gaaactagta cgccgccttt tacgagtaaa gcaacaacta
     4861 tccgatcaag aaaaataact tgcgtttttt taggaaagtg ctatgattat tttgttgaat
     4921 aaatgggatg tagccaaact ggtaaggcac ttgactctga atcaagcaat tgtaggttcg
     4981 aaccctgcca tcccaatttg atgtgcttgc tgaaaaaatg aaccccctgt aaaagaacaa
     5041 tctttttgca gggggattat tgtattattt ttactacttg tatttagttt acataattaa
     5101 attatgaata ataaaatcgg gcgtattctt aatacaaaaa ctgatttacc caataattgc
     5161 taatgctttc tccggaactt tttctctagg aacttcctca tacgtttcta tgtgtgctcc
     5221 tttattgcta attttcaaat aatgattttc ttttaacaca gaaagaccat taaattcaac
     5281 cgttcgttct ttcccattgg catcagcagc tttctgcaca taccttgctg taccatattc
     5341 atttacttcc tctggttttt gtgtctttac atagacctct cctttttcaa ctaatggatt
     5401 tagctgatca agtataccag ggatttctcc ataacttcct tcagtataat atttcagtcc
     5461 aaatagcaaa ataccactaa tcgccgccag tccaatcaaa tatttaatca ctttcatctt
     5521 tctacctcct tgttatatat tcagtatatg ggtcagttaa agaaattcca tccgtcccaa
     5581 gttggagatt tttctcctac tttagaagcg agaatcgagt gtttttttag taaaaatgat
     5641 cgttatttga tattattgac gtgtggataa atcagttttt ctcgttttgt ccatgtaaaa
     5701 aatcatgttg atagcaaagg atgtgttcaa aatgaatcaa gaagaattat ttcaaaaagt
     5761 caaggaaatg attaagaacg gcaatttcga tggcgcaaaa cgatttatcg aagaacataa
     5821 agaacaatta ggaccttata aagagaaagc ccaaaatctt ttaaaagatg taaatatcga
     5881 cagtgtcaaa aacaaattta aaaatctatt caaataagta aaactttcac ttttgtaaaa
     5941 tcaaaggagg acaatgctgc tgcatcgtcc tcctttggtt cttttctgaa tacttcatac
     6001 taaaataaac gtgtcggatc gtaatgataa gtcacattgc cgttcagtga ggcttttccc
     6061 accacatatt tacgattctc caacttcagc cacgcttctc gaaaagccat taattcttct
     6121 ctttttacat caatcttttc gatttttcca tcgatcaaat cttgaataag ttgttcatat
     6181 ggattcattt ttttcctcca tctgctgtca atcaataagt tgtaaaaata ggttcatatg
     6241 cttttttggt atctagatct tctctgactt tgactgtcgt ataaataatt ttttctactg
     6301 ggatactata ataacttcct tcaccattat tgaatcggtg aacgtctttc tttgctaaaa
     6361 taccatttat tttattcgtc agtacacgtt gttcgacact gttacttaca acatagtaaa
     6421 tcacccgaat attattgatc aaatgcaaat cgatttctaa cactacatga tccatgaaaa
     6481 tcccactcct tctttcactt tgattatagc aagtttctcc tctaatttca aaatcgatac
     6541 agattttacc ggataaatcc acaaaactgc ttgcgccatt tcgcacaaag tgttattttg
     6601 tatcatggac tttatttatc ggaggcaata gtatgatcgc gatcggtcaa tttgtttttt
     6661 atattccttt ttttattatg ataagcattc ttttctatta cataaaatgg acaaaaaaga
     6721 agttttcagt tttactggcc tctttacctg ctgtatattt tacttatcaa attttttctt
     6781 ttaggcattg ggaaacaacg tctgtattaa taacacacat catcgaattg acgctttcag
     6841 taatttttct tattatttgg atctattttt tatataagaa tcagaattga atccctcgca
     6901 tgtttaaaaa gaaaacgatt aaagatgcag caaatttctg ccgatcttta atcgtttttt
     6961 ctattctgtt ataccaaaaa aatgtttgaa tcggtgaagg atcgttcctt gttttaattc
     7021 tataaattct tgtgcgatcg ggtacttttc ttccaaattt tctttgttct tttcgatcag
     7081 gcttttcgct tcttcatatt ttttatctgc acatagtgct tttacttcct gtaatacttt
     7141 tcctgcttcc atttgcctca ccctcttgcc attttattgc tttaagtttt atttaagtta
     7201 tacgcattat tctagtttca tcccaaataa ccttttttca tttttactcc tcgaactaat
     7261 cagttttcta aaggctgatt ggttcgtctt ttttattttt cctccatttc attctgctct
     7321 tctgttaatt tatctaatgc tttgattgat gctgcggctc ttgcataatc atagctgtat
     7381 aattccataa atttatcagg cagaacaaac cacgctggat gataaccgtt agctgtgaca
     7441 gggaatcctt tatcttgttg gttatctcca tcccatctca gagcaacacc tttttttcct
     7501 ttccacttta ctaaagcgat cgagtatccc ttctttgttt gtgtgccgtc ttcaataatt
     7561 gctaaaattt ctattttttc ttttggcgca cggacttctt gaggacgaac cattttctat
     7621 tcctccctta tctcattact tcacgaccaa cacactgcaa ggggcatgtg atacgacata
     7681 agaagcggtc gatccaacta atgcttgttg tatagcacct tttcctgtcg ctcccataac
     7741 gatcaaatca atattttctt gtccagggat gacattggca atcaaatttc ttggatctcc
     7801 agtttcaact attgcgtgga tctcagcaat gccgtactct ttggcatcat tgattttttt
     7861 cagcatggct acttctgttc tttgtttttc atctgcatag atttttgaaa aggcataggc
     7921 actatgggtc agctcaactt tgttgatgat tgacacgata aataagtggg cttcattgtc
     7981 ctttgctaag tcaagggctt cagcgaacgc tttgatcgat tgtcttgatc cgtcaactgc
     8041 taccatgatg ttctggtatc ttttactcat tggaaccgcc tcctttttct tttattgtaa
     8101 catctcaagc aaaaatacaa aaaatatacg caatatgtaa ataaaatgat gaacaaaagc
     8161 aatttctttc aagttattta tacatttctt ttctcatcag aacacctgtt ctaatcccat
     8221 tatttctgca ttatgtgaaa ttcctcatca tttttcacat cgagcgaaca tcattctgtt
     8281 acaaaaaacg tggatttgtc ataaattgtc atgcttcttt tacctatgaa atattttcac
     8341 gtgttaaagt attcctcgtt gaacacaaca aataaaactt tttaacgaat aaaggagatt
     8401 tttcatgaca tcacttaaaa ctttactttt tggaacaact ttggctgccg gcgctgcatt
     8461 cttcatggga acgactgctc atgcggacga agcttatacc gttcaatcag gtgatactct
     8521 atcaacgatt tctcaaaaat acgttggtga taactccttg atcaatgcca ttgcagaatc
     8581 aaattcaatt tctgatatta acctgatcta ctcaggacaa caattaacaa tcccaacaga
     8641 aggctctgca caagcagctg ctgaacctca agcagccgtt caagaagcac cagtccaagc
     8701 tgaacctgtt caagctgaac aacctgttgt acaagaaacg gttcaaacgg aaacacaagc
     8761 agcgcctgtt gctgaaacac aacctgctcc tgctgtaaca gaaactgctg ctactccagc
     8821 aagtacaagc tctgcaaaag aatggatcgc acaaaaagaa tcaagcggtt cttacacagc
     8881 aacgaacgga cgttacatcg gccgttacca attagattct tcttacttaa atggtgacta
     8941 ctctgctgca aaccaagaaa gagtagcaga acaatatgtt acttcacgtt atggttcttg
     9001 ggaagcggcg aaagcattct gggaagcaaa cggttggtac taagattcat tatttgaacg
     9061 tttaaacaca ttcaaaatat agtaagaggt catgcgattt attctttcgc atgacctctt
     9121 tttgagttta agtttagtct ttattcctta actatcgttt gccagtattt cttgtatcag
     9181 aatctataaa tctactattt gaatcaatct attaggtttt aaactgtccc accttcacac
     9241 aaattttttt tgatttattt gaatctggtt ccgttgttta aaatttttcc tatattcttt
     9301 tagataatat gttattttct ttctcatcgc tccaggtgta ccttctcttt ataaaaaaac
     9361 aaattatgcg gctaagaaga ctcgaacttc cacgaggtca ccctcactag cgcctgaagc
     9421 tagcgcgtct gccaattccg ccatagccgc atcacatctt ttagtttagg attacatgtg
     9481 ttttttgtca agaacatatt tttgttcttt ttcatttctg tacgccctcc cttatgccat
     9541 ctacacaaat aattcatccg agcaactcca tcatctattg agggttggtg aaaaaatctg
     9601 ttttatccat atgatcgatt tcaatgttaa acgaacgact ctgggattag taactatttt
     9661 atttttttct tcatttcttt tttcctcttt ttctcgattc agctatcttc tttcatttgg
     9721 atattgatta tttcttctgt tgattactat ccttctggaa ttctagacgc tgaagtaatt
     9781 cacgttttct ttcttctaga gatcataagt aacgaatgaa cgaacttcaa ataatttttt
     9841 tattgtaatt catatttgta ttgttcgatg attcttaata cgatatgaca caataaataa
     9901 aaataggcat ggctatttac aacaatagtg ctatagtaga aaacaaatga ataaggttac
     9961 ttaaagaggt gaatacgatg aaactgatca aactatggga agcagattta aagaaagctt
    10021 atcagctaca aactagcttt ggaccaaatg agagtggatt tatcaacaat gcttatggct
    10081 atacatttgc tgaattttta gattatgtaa aaaaatgcga aaaaacgtct ttaggaatcg
    10141 atcttcctga gagttacgtt cccgcaaccg tctttatttt agaaagtgat gaacatgagt
    10201 atgtaggaat ttttaatttg cgccataaac tgaacgaaac attaagaaac ggcgctggcc
    10261 atattggtta cggcatctcc cctaattatc gtaaaaaagg atatgccaca caaggattag
    10321 cattagtact acaagaggca aaaaaaatcg gcattgatga ggcacttttg tctgtaaata
    10381 aaaaaaatct tggcagtctt aaagcacaac aaaaaaatgg ggctgcgatt tatcgtgaag
    10441 atgagaaaga atactatacg aaaatcaaac tgatgtaaaa aagaaggatt ccaaaaggaa
    10501 agggatttga atgtccttta tcaatagaac acatttattt aattaactta taatatagca
    10561 gacaaaattt tataaacaaa gaaacctttt atctcttttc ttctagaaag gataaaaggc
    10621 ttttttgttt ttcctatttg cttctcatag ctagtcagcc aagatttcta tcgtatcccc
    10681 aacgcaatcc gtgcataacg gctcatctta tctgtcgtcc atgctggata ccagactagt
    10741 ttgacttctg ctttcgttac ttctggcact tcttttaatg cgtcatggat agattctgtt
    10801 aaaatatctg ctaatggaca gcccatagtt gttagagtca tcttaatgac tgtttctcca
    10861 ttttcaggat tgaattctat atcataaatc aagcctaaat tgacgatgtc gattcctaat
    10921 tcaggatcaa tcaccatttc caaggcagca agaatacgtt ctttgattag ttctatttct
    10981 tgtccagacc gttcttggtt tgcttcgctc atcgtacgac actccttaac acgattttta
    11041 tttatcatac tcttttttta gctgcttgta aatgagaatt tagaagtaag attctcgttt
    11101 aaatttataa aaatgttctt attagatgta atagattaaa tttattctaa aataaacctg
    11161 attcctcatt ttttttgtga acgatttttt atttctggca atacgccagt tgttcgatac
    11221 attttttgtt cgttttcatt tgcaaaccgg ccaaatactg aatgagttgg taaaatattg
    11281 ataaatgcat cgtcgtcgat ttcatgaacg atctgatcaa gatcatacat ttcgtagcgg
    11341 gtgatgacca tcatgatcat gttcccttgt ttttttgaat agccaccgac agacggcagt
    11401 aatgtcattc cacgtaccat ccgttttgct agttcttctg ttacctcttc tggcttgacg
    11461 gtaacgatca ttgctgttac tttttgatga ctcgtgtgga tggcatcaat tacttgagtc
    11521 attgcataaa tggaaataat cgtatacaag gcactttccc agttaaagaa gaagcctgcg
    11581 atgactacaa tgataccatt tagaatcagc atgtagtttc cgactgtttt tccagttgtt
    11641 tgtgaaagta caagagagat gatatccatc ccaccagttg taaagcccat ttttaaagat
    11701 aatcctacgc caagacctaa taaaacaccg cctactaggg cattcatcaa aatattatca
    11761 gtgatctgtc cgactggaag cagcatcgtc atcaccgata cacatacaac attcacaaaa
    11821 ctaaggatcg ttgctcgttt tcctactttg agaaacccta atacaaacac agggatattc
    11881 aaaagaaaaa taaatgttcc tgtgtctatc ttgatatgaa accattcata taaaagcgag
    11941 gaaatgattt gagcgatccc attcatccct gcagaaaaga cattggctgg aatcaaaaaa
    12001 taatttaaag cgaccgcagc ggtcaatccg gttatcaaaa taaccactat tttctttaat
    12061 ctttcatttt tatgatacgc agtcataatt ttactcacaa gcacctctcc cctactttgg
    12121 tattccaaat gtaagaataa cagtttatct attaaaataa aatacttcga actcaaatga
    12181 gaagaatttt agcaaacagg taagaatctg ccctaatcct atgataagat agatgtatgg
    12241 taaatattta tatgtatatc aggagggttc ctatggcaaa agatgctagc ttcgacattg
    12301 tatcagaagt caatacagaa gaagtaaaaa atgcgattca gcaaacaaca aaagaattgt
    12361 ccaatcgctt tgacttcaag gattctacag tagaaatcaa attagagaac agcaatctag
    12421 ttgtattgag cgatgatgat ttcaaaatcg aacagatcaa agatgtatta tttggtaagc
    12481 tgatcaaaag aaatgtgcca atcaaaaata tccatttttc cgaatcagaa cacgctctag
    12541 gtggcaaagc tcgacaaact gccgatttgg tcaacggaat cgatcgtgaa aacgcgaaga
    12601 aaatcactac agctatcaaa aatgaaaaac tgaaagtaaa agcacaaatc caagaagatc
    12661 agattagagt gacaggtaag aaccgtgatg atctacaagc tgtgattgct ttattacgta
    12721 aacttgactt accaatcgag ttgcaattca ctaactatcg ttaatcaaaa aacgaggctg
    12781 acgtctgtca ttcctcgttt ttttgattta ctgcttcttt tgataaccaa aaacgctgta
    12841 ttccttcttc caattcccca acacttcgta cttctcttgc tgtttgccaa tgttgtggga
    12901 ataaacgtcg ataagaaaaa ctagaaaatc gttgatctgc caatacaacg attccttgat
    12961 ccgccatgcc acgaatcact cgaccaccag cttgcaagac tttgttcatt ccaggaagct
    13021 gataagcgta agcaaatcca aggtgttcct tctcatcata atatgatttg atcagttcct
    13081 gctcatgatt catctgcggc aaacctacac ctacgatcat actgccgatc aatcggtccc
    13141 ctctcaaatc gattccttct gaaaaaatcc cgccaagtac gcaaaatcca atcaatgttt
    13201 cagcgggatt tgtttgaaat tttgttaaaa atcgttcgcg ttcttcctca ttcatgtccg
    13261 tttcttggat tagcacattg ctgtcgggat attgctgtct gaatgcttcc accgcaagat
    13321 ctaaatattg ataagaagga aagaaaacga aataattccc gacctttcca tcagcaaaag
    13381 catgaatcgt ctctactaat tttgccagac tgtgttccct ttttcgataa gtcgtctcta
    13441 ggtaatttgc gatgaaaact tgctggtttc cttctgggaa aggactcggc agtttgtaag
    13501 ccagactttt ttgtcccccc agtgtttcct gataataaga gagtggtgaa aaactagcag
    13561 aaaaaagaat actgcttttt cctttatcca acgactgctc aagaaacaag cttggatcaa
    13621 tacaaaactc ttttactatc agatcgcgat acgttttttc gactgttgtt tcgtagtgat
    13681 catcataaaa ttcactgacc ttcaaaaaat gaagcaaatc aaaataataa ggaagcaatt
    13741 gttcttgtga tgggtgctca ggaaattctg ccagccattc tttaattttt tcgcttaatt
    13801 gataacctgc ctttactaaa gattcagccg gtgctttttg atgatgataa tcccaatgat
    13861 cttcttttgc tatttctcgg atcgaatcaa attcttttaa tagtttgttg aaacggcgat
    13921 gaagtttttt gaattccttt ggtatagctt ccttacttcg tttcgttttt tcataagata
    13981 gttctgccga atacatctct cgggaacgat tcaccaaatt atgtgcttcg tcaatcaaaa
    14041 acagatagtc ctcgtttttt tcatcttcaa aaaaacgtct taaataaaca gttggatcaa
    14101 ataaataatt gtaatcccca atgattacgt cacaccagat actgacatct aatgatagtt
    14161 cgaaaggaca aagtgtatgc tttcttgcat aagtttcgat gacttcacga gtgatctgat
    14221 tctcatgatt caaaagatcc cataaacctt cattaatccg attgtaataa ccattggcat
    14281 atgggcactg atctggatta caggtcgtct catctaaaaa gcagatcttg tctttcgccg
    14341 tcaaagtgac actttttact tcagctcctg tatcttttaa tgctgtcata gcatcttcag
    14401 ctacttgtct agttattgtt ttagccgtta gataaaagat cttttctccc tcttcttccc
    14461 ctacagcttt caaagcgggg aataacgtag agattgtttt tcctgttccg gtaggtgctt
    14521 ctacaaacaa tttctgtttc gtacggatcg ttttataagc agctaccgct agttcacgct
    14581 gacctttcct atactcatca tgggggaatt tcaaagccat caaagaggca ttgcgtacag
    14641 tgcgccagtt ttcttgaaaa acaagccatt ctttataatc ttcagtcagc tttttaaaaa
    14701 aagtttctaa ctgctctctt gtctgatgtt caacctttct cgtgatcact tcttctgccg
    14761 tctggaagta agtcaattgc agatttattt cttgtaaatc atgttcttga ctatagatat
    14821 aggcatacac ccttgcttga tgaaagaaaa gttccacttg ttctggttct aaatcttcaa
    14881 atcgtggttc ggaggttttg atttcatcta tataataaat accgtctctt ttgaaaatac
    14941 cgtctgcacg gccttcaacg atcaggtaat attcatctaa ttgaactgtt gtttttaaaa
    15001 agacttcttt ttcatagttt tctcccgcat ctttttggag cttgcggtgg attctcgctc
    15061 cttctaatgc agtatggtta ctttttttac gattgtcgat acttccacgt cgcaaaataa
    15121 attctactaa gtgccgcaca gatatttttg actgtttgat catttccacc acctctttct
    15181 ctctaagatt acctgaaaaa acctagttta gcaaaaagag ctctctttcc aaacataaaa
    15241 aaacaccctg ctgattaggc agggatatag gatatagaat ttggattttt ggatgaatct
    15301 aatgtaacaa ggacatatta aaatgctatg aaaacttact ttccttctct ttagaatatc
    15361 caaatacttt tcatatagtc tgataattca gataagtaaa gagaaataag tacctgtttt
    15421 tgtttcctag caatgaatgc gttatactaa tggatgaaag aagttttggc tatcaaggag
    15481 gaatgcacat gcatatcgaa agattaaaaa caggaatgat tgaagaaaac tgttatttgg
    15541 tctacaacga agaagcactt ttgatcattg accctggaga agatgcggaa cgaatcaaac
    15601 aagaaatcaa aaaaacaaac caacagccgg tagcgatttt gcttacccat actcactacg
    15661 atcatatcgg tgcagtggaa cctttacgcg cgtattatca aatcccagtt tatgtcagcc
    15721 cactagagca aaaatggcta ggtgatccga ttttgaatct ttctggactc ggtagacatg
    15781 atgatattgc tgatgttatt gtctcgcctg cagaatatga atttgaaatg aaaacttata
    15841 ctttaggaaa catgtctttt cgcgtcgtcc ctaccccagg gcattctata ggaagcgtca
    15901 gctttatttt tgatgatttt gtcgtttctg gcgacgccct gtttagagga agtatcggta
    15961 gaaccgatct gtatacaggg aatttagaac aattacttca tagtattcgg acccagctgt
    16021 ttgtattacc tgatgaattt gcagtctatc caggacatgg cgatgcaacg acgattgaac
    16081 aggaaaaaag gacaaatcct tttttcaatc gttaaaacga cttaggagga gaataaaatg
    16141 acagaaacta cactttatat cgtacgacac ggaaaaacga tgttcaatac aattgaacga
    16201 gtacaaggct ggtgtgatac acccctcaca aagcaaggac aagaaggcat tcattattta
    16261 ggtcgcgggt taaaaaatgt cgacttttca tttgcttatt ctagtgacag tggtcgtgca
    16321 atcgaaactg cccgtattat tctaggagaa cattctaagg gaaaagaaat tccttatttt
    16381 attgaaaaaa ggattagaga atggtgtttc gggtctcttg aaggtggata tgacatggaa
    16441 atgtggggtg tgatccctcg tgtattgaat tttaaaacat atgatgaaat gtttaccaca
    16501 gaagtttctt ttgaacaaat tgctaatgct gtatacaact tagataccgc tgggtgggcg
    16561 gaaacttatg aaacattgcg agaccgtgta tggacaggat ttgaagatat cgcccatcac
    16621 tgcgaaaaaa atggtggtgg aaatgtttta gtcgtatctc atggtttgac gatcgccttt
    16681 ttgcttaatc tgatcgatcc taaacagcct gttcgtgctg ggcttttaaa tggcagcgta
    16741 acaaaggtca cttatgcaaa cggtcgattt tctatccacg gcatcaatga tacgtcttat
    16801 atcgataacg ggaaaacaca tagtcgcgac tcgtttctat aatggggata ttttaatttt
    16861 taccagagaa tcataaaagg caaagtctga acgagggctt tgtcttcttt tttctcttcg
    16921 tgtacttatc tgctttattt ctcaagtttt tcttaatatt aaaaaacaga ttgggtttct
    16981 caaaaaataa cggtatacta taagatgtat cttaattggg aaggaaggaa tttatgtttt
    17041 ttgcaaatat tatcaaagca gtgattctcg gtattattga aggaataacg gaatggctgc
    17101 ccatcagtag tactggtcat ttgatcctag cagatgaatt catcaaactg gatgccagtt
    17161 cacaatttat gtcgatgttc aatgtcgtta tccaattagg ggcgatcttg gctgtcgtcg
    17221 ttctttattt tcacaagtta aacccatttt ctccaagtaa atcaacggta gaaaaaaaag
    17281 atacgtggac actttggttt aaagtgatcg ttgcttgcat accagccatc atcattggtt
    17341 tgcctttgga tgattggtta gaagcaaatt tccacaagtt cttaccagtt gccattgttt
    17401 tgatcgttta cggtattgcc tttattattg tcgaaaaacg caacaaaaac aaaacacctc
    17461 gttggacttc tctgaatgac tttacgtacc aagcagctct tcttgttggg ttattccaag
    17521 tcttggcact tgttcccgga acatcccgtt ctggcgcaac gatcctagga tctatcttga
    17581 ttggtgcttc gcgttttgtc gctacagagt tttcattttt cttagggatt cctgtcatgt
    17641 ttggcgcaag cggcttgaag atcgtcaaat atttagctga agggaattca ttcaaaatgg
    17701 aagaaactgt tgttcttctt gtaggaacat tcgtatcttt tgtggtttcc gtcttagcta
    17761 tcaaattctt actaagctat ttgaagaaaa acgactttac cgcttttggc tggtatcgta
    17821 ttatccttgg tatcattttg attggttatt ggtttattgc aatgtagaaa aaaccagaac
    17881 acttctctta tttgagaaat gttctggttt tttattttct ttaataataa tcattataaa
    17941 taataaaaac aacatcaagc ttaatcacca aatgataacc attatcgttc tcatttagct
    18001 gttattatta tcaattacat ttttattatg ctatccttgt tttgacaagg aggtctaata
    18061 acgatgacta atcagaaaaa agcttttgca gcaacaatcg gctgcctttt atttatgatc
    18121 ttcggtttta tcttcgaccg attctctctt accatcaccc cactttttta tatcagtgcc
    18181 attatcatcg gtggatataa acaaacatcg gaaggcttga aagaattgtg gaatgatcgg
    18241 acactgaatg tggatttatt gatggcttta gctgctattg gtgcctgttt gatcggtaat
    18301 tactttgaag gagcaatgtt gacattcatc ttttgtttaa gcggtgcatt agaggaatac
    18361 acaactaata aaagtcaaaa agaaattact gctttgatga atcttcaacc acaaaaagcc
    18421 caattattaa aagaaaatgg acaaatgcaa gaagtagatg tttctcaact aaaggtggat
    18481 aacttggtat ttgtcgctaa aggagcagct gttccgatag atggcttttt agaaagcaca
    18541 caggcaacga tcgatgagtc tgcattaagc ggtgaatctg tgcctgtaga aaaatattta
    18601 ggcgatgaga tgtatgcagg aacgctgaat caaggaaatc ccatcacgat tcgagtaaca
    18661 aaaacgagtt ccgaaactgt ctttgctaag attatccaat tagtagaaga agcgcagaat
    18721 acgccaactc aaacagcttc atttatcgaa cgaatcgaaa ataattatgt aaaattgatt
    18781 ttgcttgctg ttcctctaat gatccttctc ccccactttt tcctaggttg gagttgggat
    18841 gaaagctttt atcgaggaat ggtattatta gttgtggctt ctccttgtgc gcttgtcgca
    18901 tctgctacac cagcttctct agctgctctt tcaaattctg caaaaaatgg gattttaatc
    18961 aaaggcggta tccatttaga aaagctttct gaattaaaag cgattgcctt tgataaaaca
    19021 ggaacgctca ctaaaggaaa accagttgta actgacagct ttttctttga tgaaaaggat
    19081 ttggcacaac aacttcttgt tgctatggaa caaaaaacga cgcatccact tgctcatgcg
    19141 attttgcaat atttcgattg cacaatacct gaagaaatcc aatacttacc aatagaagaa
    19201 attactggtt ttggattaca aactacctat ttaggtgcgc aatggaaagt tggcaagcac
    19261 gcatatgatc ctgagacgat gataatcagc aaagagattg cggaaatgat cgaacgtttg
    19321 gaaaatcaag gcaaaaccgt gatttatctt tctaaagatc agcagttaat tgctgtttta
    19381 ggtctgctag atattccaaa agcaaatacc caacaagtaa tttcctactt taaatcccaa
    19441 aacatccata caagtatgat aaccggcgac cattctggca cagcaaaggc cattgctgaa
    19501 caagtaggga ttgaacatta ctatgcaagc tgtactccgg aagaaaaaac acaactagtc
    19561 aaaaaagaga atgaacttta ccaagtaaat gcgatggttg gtgatggagt caatgatgcg
    19621 cctgctttag cagccgcttc tttaggtgtc gctatggggc aagggacaga tgccgctatg
    19681 gatatcgcag acatcgtctt aatgaaaagc gacttaaata aatttgtcta cagtcatcgg
    19741 ctatctttaa aaatgcggcg gatcatcaaa caaaatatta ttttttcgat tcttgttatt
    19801 ctcttgttga ttgcttctaa cttcctgcaa tttttaaatc tacctcttgg agttgtagga
    19861 cacgaaggaa gcacaatatt ggttattctg aatggcttgc gtttactaag acctttacct
    19921 gatctttctg attcttcaaa aaaatgtaag tcttgtccac tatacaaagc gcggctgtct
    19981 tctgtcaaat aagcaaagtg tttttttatg attttgttta ttttatgaaa aaaacagctt
    20041 atgaataggt cttgaaggat gaattcctac ttttgtaact ttctaaaaac atgttatgat
    20101 tgtttcgaag aaagtgagga atatatttca tggaaagttg gcttttttta ggaattattt
    20161 tacttgtagc aattttagct aaaaatcaaa gtctgatgat agcggcagct tttgttttga
    20221 ttatgaagct cataccagcc tcccgttcct ttttcccttg gcttcaaggc aaaggaatca
    20281 atattggggt gacgatcatc acagcggcta ttctaatccc tatcgcaaca ggagaaatcg
    20341 gtctacgtga tctattagaa gcctttaaat cccctattgg ctgggtagct gttttttgcg
    20401 gtgggctagt ggctgtctta tcttccaagg gtgtaggatt gattgcttct gatccacaaa
    20461 tcactgttgc acttgttttc ggcacgattt taggtgttgt cttcttaaga ggaatcgccg
    20521 ccggaccggt cattgcttct ggtatcactt actgtatctt acaagtattt gctttaggaa
    20581 aatagaacaa attttgtcta ttttaggaga ttcttaacac ccccaattta ctgatccgtg
    20641 atatactgac aacgaggtga tacaatgttc gaaaaattaa agtatttcat aggaacaatc
    20701 ggctggtttc ttctagcggt acttttgatt ctgggcttag cttatctatt atttcctgat
    20761 ttgatacaaa atgtgtttga tactgctttt tgattgacct attaaaacga tataggggat
    20821 gctcctgcga tgcaggggct ttttttaatc aatgttttgt aataatttag gccgtgccaa
    20881 tgagacttcc tatagaattc gatgctcttt tttctttttg gctcttctgc tcttttttgt
    20941 tatactagat tacagtggac aaaagaaaga atgatcgcat ccacttcaac gaatatcaaa
    21001 atggaagaat tagtgcctgt tttcaggtta ctttgaaaag aaaggaagac gcttgtggaa
    21061 acttttgaag gtcttttaat tgatacgtac gttttacaag aacagccaat gatgctgact
    21121 gggatcaact tgcagcttga ggaccgtgtg atcaatggcc tgcttaaaga tcgctatttg
    21181 gcaaaatata tcttacgttt gcccctaaat aaatatgtgc tggaagtaag tggcaaatgg
    21241 aaccgtcgga accagttggt cataaaaaaa atgttgataa aaaatatcga tgaatacatt
    21301 aaaataatcg gtacaccaga atagccttta ctgatcaaag gatactggtt ataaaataac
    21361 tgcagtttct taatagaaaa acaaagaaca acagggaatc gtatcccttt tcaaaaaaaa
    21421 ctttgcaaac ggttctcttt gttatataat aacttagtac caaacattcc cattcaaact
    21481 ttgtttaaat agataaataa aaatctagtt tggtttgacg ctattgcctc ccacaatagc
    21541 gtctttttga tttttttcag cttgtactat ccgtttttac tgaaaaaaaa tcctaataaa
    21601 agactgttaa ggaaaaaaac ttgtcatgtt catattgcaa agcacgctgc ctttaggtat
    21661 aataatgaat gttgaattat gcggtaacac gcgtaagaac ttaagttatc ggaggtgaaa
    21721 ctaatgccaa acattgaatc tgcaatcaaa cgtgttcgta caagcgaaaa cgctaatgtg
    21781 aaaaattcat ctcaaacaag cgctatgcgt actgcaatca aaaaatttga agatgctgta
    21841 gcttcaggtg ctgacaacgt agatgcgtta tataaagaag ctgttaaagc tattgatatg
    21901 gctgaatcaa aaggtctaat ccacaaaaac aaagctaacc gcgacaaatc tcgtttaagc
    21961 aaaaaaatcg ctaaataaaa gaatcggctt cggccgattt ttttatttgt caaaaaaagg
    22021 acaaaaacaa acgaccttcc cgcatgcttt gccctcgtct ttcttcttat cgatttctta
    22081 acaactgccc tgtgcgcaaa acgaatagtt gaaaacttaa ttctttttcg atttgtcccg
    22141 ttttgatttg ataatccatc tcaactaatt gatcaaacaa ctgtaccagc aaatgttcat
    22201 cgaatttttt tacttcctgc atggcaagtt ttacacgata tggatggatt ttcaatgttt
    22261 cagcaatatt tgcctgctga taaccaatct ttacaagaaa ttttgtctgt aaaaataaac
    22321 gtaattgaga aagcaaaatc gcattaattt tgattgtttc ttccccttgc ataactaaat
    22381 cttcgtataa acgcaaagct tgttccgtct tcccttttaa aatatattgg gtcatgtcaa
    22441 aaatattatg ttctaacgtt ttaggaacta attcttctac ttctcttacc gtgatttgct
    22501 gttgattttg tccataaagg accaatttct gtaactctct catcattttg gataaatcta
    22561 agtcggtcaa cctcaagaat aaatcaattg cacttcgttc cattttgatt gaggaattct
    22621 ctaaggtatt catcagatat tgacgtactt ctttttcatt caactgttgg acattgatga
    22681 taattgctgt ttttttcaat tgtttcgtta cttttttccg ttcatccaac ttttcatatg
    22741 gcgcaaagaa tactaataca gtcgattcta atggttcttt caaataagcc gtcaataaat
    22801 cagtattttg ttcgattcca ttgtttactt tttcacctgt taaaaaataa ggattctcta
    22861 cgaatactaa ccgttgatct ccgaaaaacg gcaacgtctc tgcttcagct actacctcat
    22921 ctaaacttgc attttccatg tcaaaactta aaaaatttaa gtcatcttcg ccctctaatt
    22981 ggattttttt gacaatttct gtccgaactt gatcttggag aaacttttct gttcctaaaa
    23041 tcaagtaaca agatgcaagt ttttctttac gtattttttg taactctgct tgtatactca
    23101 aattactcac cactttcaaa aattatccta ccatgagcag atgagaatta ctagtctatc
    23161 attgtttcca ctagcccatg aggatgaaaa actggatgcc agcgataggt gatcattcct
    23221 tgttgatccg ttcgccatgt ttttatctga ttttcttcta gtgtctccaa tacttcgctg
    23281 tgcgggtgac cataacgatt atttacgccg caggatataa tcccatgttt tgcttcaata
    23341 tgggaaagaa aatctgtgtt acttgacgta cggctaccgt gatgacctaa tttgactaca
    23401 tcggctttca gattaggata aatcaaaagc aattgttttt ccattgcttg attcaaatct
    23461 cctaaaaata aaaagcgcct attgttatat tccatccata gaccaatcga atcttcattt
    23521 cttccctctc ccttttcaaa aggagtcaat acataaagat cataataacc gctgagcctg
    23581 tccccatgtt tgatttcaat gatctcagta ccattttttt gagcttcaga taaatgcctt
    23641 tgtaatggct catttcgtcc agcgccccaa ccgatataaa tttttttgat agtaaaatgc
    23701 tgagataacg tgggtaattc tcccacatga tccgtatcgt cgtgtgtcaa gatgagttta
    23761 tcgattacac ttatcccctg accttttaga tatggaacga tatttctttc agcaggagga
    23821 cgtatcatac cttgcgccca cttttctctt tcaaagtgta actgacctcc agtatcgatc
    23881 aaaatcgttt cttttcgaaa aggactttgc aaaaagatac tgtctccttg accgacatcg
    23941 ataaaagcga tcgttgaaga aaagcgtaaa aatggcaaag tcaaaaaaat aaaagaaaaa
    24001 agaccaacat aaaacaagtg tttcacaggt tgttctttca acctatccat acaaatcagt
    24061 aatccgaaaa tatacatccc agatagcaca aggggcaaac gtcctataat gagagacgac
    24121 cctgaagaaa aatcgattat tcgctcaaat aagattaatc cctcttctat cagcaaaagt
    24181 aaagtttccg gcagccagcg attgaagagt gtgagaaata acacaccagg aagaaaaaga
    24241 aacttgaata ccggtgcaat cagtaatgta aaaagactac ctaaaatagg ccactcataa
    24301 aaatgccata caatcaacgg catcgtgatc atagtaaaca ggacgtgaga ggccgttttt
    24361 ttcaaccaat ctccatcaaa agaaatcagg ataaacaaaa aactcatgaa aaaactaagc
    24421 tgtccacccg catgaaaaag aaatcgagga tcaaatagta aaagaagcca aaagacaact
    24481 gcaaataagt ccatggtgga ataatgctta ttcagcaatt tgactagcaa tcgcaataaa
    24541 aacagcaaac tagcacgcaa aacagaaata gaacttcctg caatagaaac ataacagata
    24601 gttagtagac tcaacggaat aatactgacg tgtagtggcc atccgatacg tcgaaataaa
    24661 taatacagcc accctaaata aaattggatg tgtagacccg atagactgaa cagatgcagc
    24721 aaaccactct ccctaaaaat ttcttctggt tctctgaatc ctgcatcttt atagccccat
    24781 aataaagaat taatatatac acttgttttt tgcggaaatt cagattggac aaaggagata
    24841 aaagatcctc tttttctctg aagccagttt cgccagtgat tttgcatggt gatctgttca
    24901 atcttttgaa tttggaaccg tccagaaatt ctatggttcc tgaagtaagc ttcttggtca
    24961 aaattataaa gattccgctt ttttgctgga gagatgaact cgccttcagc agtcaattct
    25021 attccctttc ctcggaagtt aagccatgtt ttcaattctg cttctgtgtt tacttgataa
    25081 gaaagctgga gcttttgttt attctctgat aaccttcctt ccattgtcaa aaaattacca
    25141 tttgcacgaa tcgtatctgt aaatacagta atttgcgcag atgttgtttt ttcctctaaa
    25201 aatgaatact cttgtagcct ataagaaatg gataccgtta tgctacacaa aatacacaag
    25261 tacgcgataa aacgtccttc ttttagcgaa aaccataaaa aaattccggc aagaagcaaa
    25321 cgataacccc aattgtcagt gtaatacaac aaacagataa tcatcgacgt aattgccgga
    25381 aaaatcaacc gatttcgaac atgcctttct aaaacgctag acatgttttc ctgttaattc
    25441 attttgaagt tttgaaaaat gctgtgagtc taaagcaact tggtgtacag atacacctaa
    25501 ttgttcgatc aacgcttggg cataaggatc atttcgatag tcatggagat aattgatccc
    25561 tttcacacca gcttgcaaca aagcctttgt acaggccaaa catggaaaat gtgtgacata
    25621 gatttctgaa ccttccgtcg ggataccaag ttttgcacac tgtaggagtg cattcatctc
    25681 tgcatggatc gttcgcaagc agtgtccatc cacgacgtaa cacccttcat ctatgcagtg
    25741 gacatctcca ctgactgctc cattatagcc gccagcaatg atcctttttt ctcgaacgag
    25801 tgtcgctcct acttctaaac gtgtacacgt actacgtaaa gataacagta ctgcctgagc
    25861 cataaagtac tggtcccaag gaatgcgttc attatgtgac ttatcagtaa ctttttcttt
    25921 attcgtatcg catgcttttg aagatttttc taacatgttt tatattcctc cgttttttca
    25981 agttgattaa aaagtactca ttgcttaaac aaaatattct ttaaatataa cgaatcatcc
    26041 tgtctgacaa aagatcctac ccttcactgc cgaaatgaag tccgtcatcc attagcccat
    26101 tataaaaatt cttcgaatcc atttgttcaa gaaattccgt ataaaaatcg atacttcaca
    26161 atcatggcgt tttgctactt ctgtgagaac agagatatat tctttgatca acttgttatt
    26221 ccgatatttt tgttttgtct catcgactgc tggtggcgtg ataaagaaag catgatcaga
    26281 actatagtct tttttcagct gaactatcat ccactgcaga ttttttggta cgtttcttta
    26341 gaaagttgtt tatgctctgc tagatcattc gtcccaatga gaataaatac tttatctgct
    26401 gtatagctaa gtacatcttt ggcaaagcgt tctcgtagag cttgactgtt attgccgctg
    26461 acagccgtat tcataatatg aatcccagat attttatttt ggagatagac attcagcatt
    26521 ggttttttta atgtttcttt gcgaacaatc aagctatttc ctatccaaaa atactacctc
    26581 ctcgtcctgc caagctctta gaattggatt attcttagta tccattagcg tccatttatt
    26641 gctcgtgcca gtcgattttg aatcattcta tttaattgta acgaagtttt ttagtttttc
    26701 aactgtcttt tcaccgatac cagaaatctc ctgcaggtct tccactttct ggaaggatcc
    26761 gttttcttct ctaaatcgaa tgatttcttg cgctttgact gatccgatcc caggaatctg
    26821 ctgaagttct gatggagtgg ctgtattgat atttattttg ggaggctcgg aatctgctgt
    26881 aggctgtttt ccttccgagg atgccaactg atcaagatgt tctggcagct cttcacctac
    26941 agcagggata tataggactt gctgatcttc tatcttcgca gaaaagttga ttcgatcgct
    27001 atccgcttct tctaataatc cacctgcacg ctttagtaca tcatagaccc gttcttctga
    27061 agaaaaggaa tagataccag gctccttcac acttcctttg atatcggtgt acatgacctt
    27121 tggacgagca tcctcttcta catcgtttcc ttcagctgat ggatcttctc cactggaact
    27181 aaacgaagaa agtatttctt ttgcagcagt ctcttctgtt tctctataaa atagcaaatt
    27241 tgataataaa aaaccacttg cgatacaaaa gataagaact atcatagaca tccaaatgat
    27301 caatttgggt gaagctagta ttttcttgct gattttttct atcattgttc ttttttcaaa
    27361 gaatgaccag taaaaatcat tcattactcc tttcatttaa aattgaagaa acagtgagct
    27421 ctggcaaaat cgtcccttca acatctaatt acgtcaattt tttcttttgt ttttattttt
    27481 atcgtgaaga tttttgacga aaaagagggg ttgtgacaga actcgtgtca c
//
LOCUS       DAPBAF010000040        27054 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.040, whole genome shotgun sequence.
ACCESSION   DAPBAF010000040 DAPBAF010000000
VERSION     DAPBAF010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 27054)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27054)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27054
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.040"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            4..243
                     /locus_tag="RD451_002025"
     CDS             4..243
                     /locus_tag="RD451_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567260.1"
                     /translation="MARPVLEAMDMDTLTKGRYVQLLARGYSPKDVFKSLSKGTDMEK
                     ERLRKEFDYWRTHNGIKDLKPARPVIKRKKKITQD"
     gene            310..549
                     /locus_tag="RD451_002026"
     CDS             310..549
                     /locus_tag="RD451_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567261.1"
                     /translation="MNYEEIENRKKVSKEMEEKLLKMMKQKHLKRLSVMQYINDMKIT
                     GKEKACLLGSMKNFEQLRRTYVKTGSNCQLLLEVS"
     gene            676..1365
                     /locus_tag="RD451_002027"
     CDS             676..1365
                     /locus_tag="RD451_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase"
                     /protein_id="HDT7567262.1"
                     /translation="MNKNNKTLFNPYVGVIIVFLLFSYFAYQGYQKDKIAEKVDGVTK
                     TIHIQEQAKTYQDNLTSLTDISKRQLITNQKQALEKDLKGEIAGKLVFSSTGFILPVF
                     QGANSDTLSLGVASTYYLDTEMGNGNYILAGYNVDTPSVLLSDMTDLSEGEEIDLIDA
                     HYKYQYEVSKRGKISDYSQVVQSKENNSFLSLPKAGKKPLLTLLAFQANNMKKCDVIQ
                     CELVNVEKINK"
     gene            1371..2537
                     /locus_tag="RD451_002028"
     CDS             1371..2537
                     /locus_tag="RD451_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HDT7567263.1"
                     /translation="MSHIQELVEKLINKMSAIFLLLLVSILYLIWTVGLNPPTILFIY
                     DNAAQLVTFFVGCLFLLNLYKVKRNDLFFIAAGILFYLFFSFFRSYRGDTFYGDLIVP
                     TIIAIILIVKWTKFTVIDRSLYLVVFYVFLLVTVYRVFTEIPVPEGQSIWNPSNKLSD
                     IWINTNTIGSSLMTLALLITGFASSFGKWYMRLLSLPALILAGATIWVCQSKAALYAL
                     VIFIILEILPKKVFRNTHLSFWMYAAVSVLALPISYFAAMSDKVHLFTGREEIWRKFY
                     ETLGEKTGQIFVGMKPFFFHRGNQILGNHNTYHALVNHYGLIGFVLSIILLLSFLWLL
                     VRKRELTNGQLTFLWAFLAIMCQSFMEETLTTISWVPIVFLMLAMATHQYKTTR"
     gene            2619..3290
                     /locus_tag="RD451_002029"
     CDS             2619..3290
                     /locus_tag="RD451_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HDT7567264.1"
                     /translation="MKKWLFGFLGVALIVVCSVFGYVSYQKHEGEVFKQNIEKKMPVD
                     QINAHAKSYKEDATNVNNDMSLGQMLSIQKEAIEMGVNKQVFAQIQIPALGLALPIFK
                     GANQYTLSLGAATYFYEDAEMGKGNYVLAGHNMEMPGVLFSDIQKLSLGEVMDLVSND
                     GVYRYKVTRKFIVPEYFKLIDGVPEENSFLSLPKKGEKPLLTLFTCVYTSQGKERYVV
                     QGELQ"
     gene            3343..5319
                     /locus_tag="RD451_002030"
     CDS             3343..5319
                     /locus_tag="RD451_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HDT7567265.1"
                     /translation="MAINRYVKKAGMIVGMLGIIAGCFQGYRAYAEDVTQKTPPERVN
                     ITVHKLMYDQSTQLNVDIDGIKNDGYTHDQYPTGVTKYNKADYGDVEFTLGNITDQVL
                     PTEDSDLTNAKVDEIVKDVEDKGSNSEYVKNATNKITSAVDENGEITFADQPAYVNSK
                     GNVYVVYESKSAAGLVTQKAKPMVVIAPMTDNTGSGFLKDIHLYPKNIVSKLSFELTK
                     FGDDGTAQSKQTPLKGAKFELYKGEPGKGTKLGELVSDDQGKLTATDLTLGKYYFVEV
                     PSEVVVGSDQEPTADQYLLGADARNDAHNKLTFEITNDGVTSDLKASYVNYKAPVIDK
                     TVTNGTGQEHSFQIGDAVNYQGTIHIPTDIAGGADGITVNGVKSETSPYSVFKWGDTA
                     GQGLSYVAAKANIKVTNKDGSVVLKENTDYKIQNSENGFVIDFIVNNGQVSDTVASLH
                     GQDLQMTYNMYVNDSAAVANPLTNSVDFVYNNNPFNQEEHHEKTKADVVTYGAKFLKV
                     DSGLFGTGIKATPLEGAEFAAKNAEGKYYGGLVDTDKDGVKEAVWVDDVANAAILKSD
                     KEGHFEITGLTEGDYSLEETKAPENYQKLTKEISFKVDKDSYKEENRITIKNNQKASV
                     PMTGSNGFQTYVLISCLLLGAGALSAVVYFKKKA"
     gene            5334..6086
                     /locus_tag="RD451_002031"
     CDS             5334..6086
                     /locus_tag="RD451_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HDT7567266.1"
                     /translation="MIIRKPKKKRIMGKWIIAFWLLSAVGVLLLMPAEASVAKYQQNQ
                     QIAAIDRTGTAAETDSSLDVAKIELGDPVGILTILSISLKLPIYDGTSDKILENGVGI
                     TEGTGDITGGNGKNPLIAGHSGLYKDNLFDDLPSVKKGEKFYIKVDGEQHAYQIDRIE
                     EVQKDELQRNFVTYLEPNPNEDRVTLMTCTPKGINTHRFLVYGKRVTFTKSELKDEEN
                     KKQKLSWKWLLGSTVFLSVMIIGSLFVYKKKK"
     gene            6102..6863
                     /locus_tag="RD451_002032"
     CDS             6102..6863
                     /locus_tag="RD451_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567267.1"
                     /translation="MRNRKWLFVCAAALFSFTAYTQLTFADRQESTDSTEQTIQTSDS
                     STIQSSDETVDSSTVDSSEEPKIAEDDQIVKQTIHVQKIISSEQLDNQGQKLEKQEGV
                     NGAKFSVYDVSDILQKMDVKDLTTDQIESQLKDRVKKLSSDQLKLISNGETKTIDQQT
                     GVFEFSVEVQANQKQAYYIVNESSPENISNSEDILLLTPVSDKNGEFLKDVWIYPKSE
                     ASQPKEEVKKIVSTGVKKNFFENCWDFVTHLFSRD"
     gene            6876..7136
                     /locus_tag="RD451_002033"
     CDS             6876..7136
                     /locus_tag="RD451_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567268.1"
                     /translation="MKLIKLLLFNFSCLTAVFLYCGLLFSKLSILPSYQLYLMRILNI
                     PAASMPLDIMEKLIRNPLFTTINLIVIVGISLVIYKKEGMKG"
     gene            7133..9223
                     /locus_tag="RD451_002034"
     CDS             7133..9223
                     /locus_tag="RD451_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HDT7567269.1"
                     /translation="MNFKHSWTRRLKYVFPIMMMLGTLFGLKTANVFAEKVIVDPSNP
                     IQNVKNNFIIPKDVPNAKTNITVNGASKVYKYHVDANKGGFTDDYVGLVEGNKNIRYP
                     SFQKEYGETNLVLEGVTTNTKVNIDYGKIGTYNGKKVNIKLVLSNIHLYSDTLPWNLL
                     DNNYTKTHFRDDGYKNTNGAMSKSKKRTVLWISDNLFSGIVYHSTQMNVQLVATYEDG
                     SPVQFSGDTFISFNSLNPAGGKSTDLKGEYAHYDKMNTTDWYVRKDTVLSEFKSFYNN
                     LNVVGGHPGGSSKLTQADNDFNNLHDKLGDPKFGQGTVSFKISEANPTFVIGSSNVQT
                     WFTLSSATIFSVVPDQPEKTGVDKNGNNVNDKMLQVGDTIQYRIKQKVNRLGVDLLAV
                     YDRFELIDNLPKEVNYVDAHVESGTNKKFDVSGEVTYDKTKHQVKYAAKADTLKNRMK
                     YNGETYELVINVKVNELANQNSVAKNQGTSIINKVEKDTNIITVYFPKIPVKEVQQNG
                     KDVNGRNDGKKGTPTAPLNAGSEVQYLVTQKWHTKGVDAASDHYKQFSIQDPIEARLT
                     YKEGSAQVIDKSKGKDITSEGTLTYDSNSRTLKWEASADFLSNNLLDGREIQLIFTAK
                     TPLQSEKNIDNQAVVAVDNVSNKTNVVTIGVDPNLPQVIVPKTGSTHLVTISAVSLLL
                     LVLATFSYAVLRYI"
     gene            9250..9714
                     /locus_tag="RD451_002035"
     CDS             9250..9714
                     /locus_tag="RD451_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567270.1"
                     /translation="MKKLIIVVTSLIAMIVILVGCSNEKNKQINQDNGVLKSGTMWKE
                     EVGGLVYNLKIIDETTWEYSESVWHPDPVQITVKRQKDYKGLERYKIVDSAGVREFIN
                     KSDSLFIVVPYEKNGVKKIIFLGSSKDEKRTKEKLIHDGSQSNKYKLQKTSE"
     gene            9711..9953
                     /locus_tag="RD451_002036"
     CDS             9711..9953
                     /locus_tag="RD451_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5415 family protein"
                     /protein_id="HDT7567271.1"
                     /translation="MIASLFICPEGGITVAKAKTPFEKAASKILERRGVSETQWKQEV
                     LEKAQFDLLRGKDKDLEGYIYQREREKLVFDEIIKH"
     gene            9971..10273
                     /locus_tag="RD451_002037"
     CDS             9971..10273
                     /locus_tag="RD451_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567272.1"
                     /translation="MFESITMNFLTQPKVVAAVDIFRALQTAATSLKNNLMIFAAAAA
                     VASIVIGGLFFLFGRRGAENGKMHVGYVLMGVGVILAAASIVVSLFGLFGQTPQGL"
     gene            10343..12397
                     /locus_tag="RD451_002038"
     CDS             10343..12397
                     /locus_tag="RD451_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567273.1"
                     /translation="MYFTIAGNTKTDKELIKKATKEVGKRTSFLPKTIKYSVIETEEQ
                     LHVLGKVLEHESRSSVKLTLTLHDTEGKIEKAGTEYVFGPLDYQISEGFYPTLMDLIR
                     LDVFKETDETMSVEESYRNEKLLQVLEEELESDQRKVNQGSEVEVNEEVPWERPIFPK
                     KESKEKETVYVDEQADIPTQKSIFEEENDVMGQLEVDPFEETMEDEETAEVEVDPVEA
                     NEESTWTEGDSQEYIEPLISEEVEKNEIEIQKATVFDYILDQYPPEHEWMKEKNKLFL
                     NELYSKYQLPQTYQAFLESKEELISQGKGTLLEQLESVQSTNWHELAQEDLLATFEER
                     QQETDQEINEYATEQSSNWERTKEELNKEEQRVIEEEVQKIKERYEKKRDNAYSLCIE
                     KINNFTKTNQEALSKEKENLLKERIKERKEEFYRGLRTDKLKISKELNEQLNKLYQTT
                     TEVLMERHGQIQQELQAQIPKWKKEYEIQQQELKEQEEKQRQEEKEREQLELKKREQH
                     LAEQKVAIEKQRLEQEKEKEAAARKERQEQMDTLRQAQLNYLAQPQPVAAVQTPVNNQ
                     ANLTPSPQRSFNGWMVGCIASLSLLLGGGTVFAFNHINQSSQADSVATTASIKEEAQE
                     QARKEYEQQLEELLNRTNQSTAESSMENSKESDPSKAKEGSSDSTVHSNTSESSESNE
                     VK"
     gene            12397..15006
                     /locus_tag="RD451_002039"
     CDS             12397..15006
                     /locus_tag="RD451_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HDT7567274.1"
                     /translation="MRIRETTRRKDKRFNLEKNRYLSHFYRYTPSGEELPEKHDKRIS
                     QKIFYSGLAYLPLNYVVTRIPEAFHRFEIIPGSLQGVNIFQLQEMPQLFHFDSTGFWN
                     PLTPTTSLGTRLVVSTICVVPAVLMGLKMDMWFRPLADGQKGDNRLKTLKEIQQIYPQ
                     IPESKGSFPGYGGIPITHYKKYWYIQTDTVNTCIVGTSRSGKGQIEVLATIDNLSRAE
                     RQSSMVVNDPKTELYVASKDELEARGYDVYAFNITDPLQSMSDNPLALIVKYWKRGDI
                     DTATQLTNTFTNTIYYDANASDNKYFNENAQKAVNALIFALLEQADQTGDYSKLTPNN
                     LVELLSEIGGFNYQDPDNEFKQLNALDEFMNQLPPGNIAKKQYGATKIGSDKAKGNIL
                     STAITGLNPFTLTKIAKMTSQSTIDYKSIGFPKYLDLKLHESLLNQRIVVEFYHQGKK
                     FHEERVKVGYRGFCEINFDCHLEQGDHVCLKYDHRGKEYVAWYEFSQRVLKDEEGNIV
                     YRKKRGETHLPELEKEAVLTLDEDKSNLLVESIRMHYTDKPMAIFMLTPDYDPSNHII
                     VSIFLSQLYKELSTQCVKTKGDKCHRRIHFILDEFGNMPPMDNMEGIMTVTAGRNMLW
                     DLFIQSYQQLYAKYGEQNAAIIKENCQTHIYIMSTDDNTIEEFSKKVGNKTVEQENST
                     INSLGMNTHINRNVDSDRILTPERISTFLEGETIVLAPLKRQDLKGHKIRPYPIFNHG
                     ETNLPYAYQYIEDFNPSWDINDIDIHCTHADLDLKALQIDYDYFLPDIYARRLYHNMH
                     DQIEEEAKENIFIKIVQSLDNSTAQKLLIQFYEEKQIDRLQEYLEKLRQNEEITEVIR
                     KRLLLEAEKAVKE"
     gene            15003..17375
                     /locus_tag="RD451_002040"
     CDS             15003..17375
                     /locus_tag="RD451_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567275.1"
                     /translation="MIIGGIFSGIADWWSGLFGDGDADPKTVTKVLQDYGNYLQYQDV
                     FSWICNTFLWGLIKGLYNLNTLLEKTIYQSFDLKDLLNAAGVNELFQSLISKVLALFC
                     VVTLIYLGLKFFMSKHPPKIKNILVNLFMAMILIFGGSSLIDEGLNISKNFYGDVTAA
                     NKADKTGSPAFQIIQNNVIDVSTLLENDPNKVEHIPTDKRNALTAKNFKTANINGIIT
                     PDQAKKMSESSDISTVQKDRLKALQYRLELDDNGKEIPVQISDEGLAKYVYTSGYRRY
                     ISSPGIILAGESSLSVAYLFILFTIVTCIIELVFKKFYLVIAASTDFETGQRMKSAIE
                     DISQSFLLLAFTILELRIYTLMLSGIGDLHAAGKINGFLYVVALIVLTIALFKGSQSV
                     TKIFGVDTSLKNGSNSLLSMFALGNVAKNVGSGAKNLASAGKSGLSNLNDIRKNGFGN
                     RKDVTPDNGEEQSDDKATTVPNSKKTVSEMFGKAKNGVSKAAEGLGYVNERGLKGTAE
                     DLTEKAKDTLEEKLDGTRAKELAEAVKNPSETLEKQKEKASEVKEGLKDAYGEGQVNA
                     AVKANTTTEKENQEGAAIPSAKDHQDELHSNENSEEGQNGQLPKTDPEQYRYKSNINS
                     ENEKRISDLPKRNQEVQTDDDSIDLPNDNGVEVGTEKSTKIGLPKAQNLPMKDSRLNQ
                     FKENDQSFVHQSTAGNVQMKPSRLPENGNLTTVSYNLSESGETGNASVQNVVTREAAP
                     EPIQRVHTGYKPANVAFTAPTKINVTRETKNRNNALKEQLLRDIKQDIKP"
     gene            17427..17759
                     /locus_tag="RD451_002041"
     CDS             17427..17759
                     /locus_tag="RD451_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567276.1"
                     /translation="MDKYSNMKNPPRFSGEWKFFAFFFLDLLTLGGCFFWAKMVNNLV
                     HLPLFFALLNYGLWIAIALVIVWRPYNNPGQRQIFAIIESIFFADKNHYHALDPNRNY
                     HGTYKEDE"
     gene            17760..18353
                     /locus_tag="RD451_002042"
     CDS             17760..18353
                     /locus_tag="RD451_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567277.1"
                     /translation="MRVKGQNSVERKSILQFGKPEERSILDLFPYKSCTEEGVLITRE
                     DHFQRYYRVVSTDVEGLNEQEKLERMNQLTTVMRTYVPTIKLVSLTTETDLTEQIVQK
                     RQLLDKNRMEQSLGRNLQRLKKYEKKLVEEIQELKRAEQERPDLSFFFVIEGKTIKDL
                     QTRNRQLMRSSGILGLKPLYKKELIKILYRMNNMNDE"
     gene            18516..20540
                     /locus_tag="RD451_002043"
     CDS             18516..20540
                     /locus_tag="RD451_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HDT7567278.1"
                     /translation="MLEAIKTAFSPQNDQKVLDPLKQLGNREIEIVKSKGYDLDFLKQ
                     VMPQGGLNFDEEYVTYGNGYSRCVTVYHYTKNPTLFWLANLMNNPHTVATLDVSTDEK
                     QKVIDQINRALDELNDRSDNERKATDRNKSAEEYLELAEYARKLTSNGEISKQVKVRV
                     HVYGNTIQEVDERAQELIENLKGMDYRAVTYLHKTKRDWQSMFTMFDEQAEWFGNIKG
                     QSLPSLNIGGGFPFHHQTLKDPGGTQYGETMTGGPFVWNATYKNSVRLSTNTLLLGMM
                     GAGKSTVLKMIAEAHLAAGDFIWGFEKGKDFIPFLKEYNGIMVRLDGSDGMINPLEIF
                     ATRTYDEASSLYDDGSVKDLKINEAASYQTHLDKVVYQVQLVSPQLKGTMKAEFKTYL
                     NRFYEEYGTVPRGFTSSNSRSNTDTQVTGKDPEAYPTFKEFLAFLGQLELPGASQEKK
                     NRKEEMESIVESLCETYGMIFDGHSTIRHLDQQQLVFFDIDSITGLDRGVQQCQMYMA
                     MTLIWNQALIQGRRQRRLIKEKQMEEQDFKRFLAMIDECHNAINPDFIETVNYVTNFQ
                     REMRKVEAMTVLATQSPQEMVPENMSSDNFSKLKKVFEFSSTKIFMRMDESILRHIEG
                     LVGKSMTNSELESIPQQNQGDAVINFGSKETIRVHFSPNKRQLKLFDGGK"
     gene            20540..21745
                     /locus_tag="RD451_002044"
     CDS             20540..21745
                     /locus_tag="RD451_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HDT7567279.1"
                     /translation="MENQNESLIKQYVKRRAKRRLFLWVFGTSAGLITILITVFVTLF
                     LILAAGSIDNSDSDSSSGGEAFTGEYSEGLPIYKEIKGRGPFSDEIAQYAVGAAVKYK
                     LLPSVILSQYGYESAFGTSASARNDLNYFGITWFDGCLFPKGTARGIGGIEGGWYMKF
                     PNSKAAFSYYGFMVATQSNFNACVGNKSPGASLLILGRGGYAAAGITEDSPYYTGCMS
                     IITSNKLTEYDEFAIKHWGEGGNNNGTITGEWTNPFPGSSLDKSSFSGGQLFGTNPGG
                     EFRPNGFHDGLDFGSVDHPGSEIHAVHGGKVVYVGNPGISGLGACVIVINYDGLNMVY
                     QEFANSTGNSRVKVGDQVKVGQVIGIRDTAHLHLGFTRMDWRQAQGHAFIDDGTWIDP
                     LPFLNSSKK"
     gene            21761..22405
                     /locus_tag="RD451_002045"
     CDS             21761..22405
                     /locus_tag="RD451_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567280.1"
                     /translation="MENKTLKIVLTAAISVSLIGNIALFWQLKEEQAANTYKIEEVAK
                     NASEKLKKNSSEAQAKIDKLNQTINEKNQEIDQLKQQDGTKAKEEVTEAQRKTAEEFG
                     QLAIDKSLSRNELTEKLKDVATQEVIDKLSPTDDDHQHDDYGSYSFTLGDVQTYAQTS
                     SVKEEQNFVVFVDYTIGNPQFKDVKPQKIKGGLTVTDKQVDGQWKVIDFSYFTR"
     gene            22416..23222
                     /locus_tag="RD451_002046"
     CDS             22416..23222
                     /locus_tag="RD451_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567281.1"
                     /translation="MSKKKGERQRFKKRKSYLQWLGIFMILGFLILASPIYTNQKVDI
                     PDEVSTNAFLNTKELTMVSKEKGANQQLVFEFSIDDEDQSLLKELANLNYRVEVKTAK
                     GDYQAIRAKVIKVSDDYFAVKLAHVPEEYIAMRLTIIPEKIDPKVDMQEPQDLIYYVH
                     EDKVKDQVKDEDYEQHAINYKVKGYKKEQKAAQKQMESFQATIDLNEELVKKLKEQLP
                     YQVADDQENTENKINSYQQEIETSKTQLKDQEEIIQKLQEKIDRMTKEKI"
     gene            23244..23474
                     /locus_tag="RD451_002047"
     CDS             23244..23474
                     /locus_tag="RD451_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567282.1"
                     /translation="MKRTNLADKDTFAEQKVLIKAYLKVVKAKEICREVNLSNTTISE
                     LKNGRKNLDTLKFRSFEALYIAAKKYFTADNK"
     gene            24020..24295
                     /locus_tag="RD451_002048"
     CDS             24020..24295
                     /locus_tag="RD451_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567283.1"
                     /translation="MDLLIRNIEEKYINKIDKRCEELTVKTGKKWSRNQYLKVLIEND
                     FDHALLNYKKDQFDRLLEKFVDIQTYNTKTLEEYIATNNQLIGLLIE"
     gene            24337..24759
                     /locus_tag="RD451_002049"
     CDS             24337..24759
                     /locus_tag="RD451_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567284.1"
                     /translation="MAKATRKHVYLYDMHIEVLDEIISTHEDISNYSEAVRHLCMMYD
                     PKIEEKINPIQIKLNAMGKEISILTEMVSEFADLHLKDTGILIGTNSTVYQEAKERVE
                     GKIKSNKTKKYSPQLKKPVNESVHARVDPFDPTKILKR"
     gene            24778..26370
                     /locus_tag="RD451_002050"
     CDS             24778..26370
                     /locus_tag="RD451_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567285.1"
                     /translation="MNKSPAVILTCQFTLPNKKSFSTYIDYMTREKALEEKERRTPDE
                     EQELQRIKNALEDFYIPEGETFSESKTDKEFSETSNEAQSLMEHGINFDKLEEQDFTK
                     YLSYMTRHYALEQKKELTQREQKEYQRLNQAMKKYQTEPHKKASGNLPGVFSMASDEV
                     KGSDLKEIKQIFQRGQQKGSIIYQDVVSHDNSYLEKMGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNTKHIHIHFAVVEKENTRKPYTEVENGVSYIVPKG
                     KRRQATLDAMKTNYVHELERFSYEKDRMIGMEKRNLLTRKSDLRNTLTKVVKEPARYD
                     RHAMNLLNEVYKTLPDKRSEWHYGDEKRTKLSPYTREKLDELTKYVLTKEPEYQEYIQ
                     ISKSLKEEAKSLYGESKRESKDAEKNALFDLKKRTGNAILTELKKQDSQIKPLIESMD
                     QMQSIYNERSFRTLKQLPTNEYKYSYEEFMKRRKQFQQRVVTQRSLRQLNRTINAHEE
                     KYHASKAYEEQQRRIQMEQERQ"
     gene            26391..26726
                     /locus_tag="RD451_002051"
     CDS             26391..26726
                     /locus_tag="RD451_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567286.1"
                     /translation="MKQYLDQWKVIEGSLREERIEQLPDCLEKEHLFQIREMLRNEQF
                     DPNQFLVVEYPATGVYCCNHVKGEKYFIIQEYEGKLAPYYTTWEMNEEGINNFPCKSI
                     EESISLTEC"
     gene            26867..>27054
                     /locus_tag="RD451_002052"
     CDS             26867..>27054
                     /locus_tag="RD451_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567287.1"
                     /translation="MAHSTIGVVVEKSRDNLVFVTEIQTGRSFVVTDKAAKAYRSGDI
                     LALNLITKTFVDAVENYP"
BASE COUNT         9969 a         4232 c         5493 g         7360 t
ORIGIN      
        1 tagatggcgc gaccagtttt agaggcgatg gatatggata ctttgacaaa aggaaggtat
       61 gtacagctgt tagctcgtgg ttattcacct aaagatgtat tcaaatccct gtctaaagga
      121 acagatatgg aaaaagaaag attacgaaaa gaattcgatt attggagaac ccataatgga
      181 atcaaggatt tgaaaccagc acggccagta attaaacgaa agaaaaagat aacccaagac
      241 tgaagtgtag agcgtatgtg atcataggct tttttatttt tgcaaaaaac aagaaaggta
      301 ggaaaactca tgaattatga agaaatcgaa aacagaaaaa aagtgtcgaa agaaatggaa
      361 gaaaagttgc taaaaatgat gaaacaaaaa caccttaaaa gattatctgt catgcaatat
      421 atcaatgata tgaagataac aggaaaagag aaagcttgtt tgttaggttc aatgaaaaac
      481 tttgaacagt tgaggcgaac ttatgtaaaa acaggttcca attgccaact attattagaa
      541 gtttcttgac gattatgata tgaaaatgat caattatgat gtggcattgt tattgaataa
      601 aaagaatagt aaaatttaac atggtttatc ttggttagat gtaggtaaat taattcatat
      661 atagaaggta gatagatgaa taaaaacaat aaaactttat ttaatcctta cgtgggcgta
      721 atcattgttt ttcttctttt tagttatttt gcttatcaag gttatcaaaa ggacaaaatc
      781 gctgaaaaag tagatggtgt aacaaaaaca atccatattc aggaacaggc taaaacctat
      841 caagataatt taaccagttt aacggatatt tctaagagac aactgattac taatcaaaaa
      901 caggcattag aaaaggatct caaaggtgaa attgctggaa aacttgtttt ttcttctaca
      961 ggatttattc tccctgtttt tcaaggagcg aatagcgaca cgcttagttt aggagtagct
     1021 tctacttatt atctagatac tgaaatggga aatggaaatt atattcttgc tggttataac
     1081 gtagatacac caagcgtttt attatccgat atgactgatt tatctgaagg agaagaaatt
     1141 gatctaatcg atgctcatta caagtatcag tatgaagtct ccaaaagagg aaaaatttct
     1201 gattacagcc aggtagttca atctaaggaa aacaattcct ttttatcctt gccaaaagca
     1261 ggtaaaaaac cactactcac actgttagcc tttcaagcaa ataatatgaa aaagtgcgat
     1321 gtgatccagt gtgaattagt caatgtagaa aaaatcaata aataagggaa gtgagtcaca
     1381 ttcaagaact tgtagaaaaa ttgatcaata aaatgagtgc catttttctg ttactgttgg
     1441 tatccattct atatttaata tggacggtgg ggttaaatcc tcctacgata ttatttattt
     1501 atgataatgc tgcacagtta gtgacgtttt tcgtaggctg tttgtttctt ttgaatctgt
     1561 acaaggtaaa gagaaacgat ctattcttca ttgcagcagg cattcttttt taccttttct
     1621 tttctttttt tagaagctac cgaggagata ctttctatgg tgatctgatc gttccgacaa
     1681 ttattgctat tattttgatt gtaaaatgga cgaaatttac tgtaattgat cgtagcttgt
     1741 atcttgtagt attctatgtc tttttactcg taacggttta tcgagtattt actgagatac
     1801 cagtaccaga aggacaaagt atttggaatc catcgaacaa attatcagat atttggatca
     1861 atacaaatac gataggtagt tctttaatga cattagccct tcttatcaca ggatttgcta
     1921 gttcatttgg aaaatggtac atgcgattgc tatcattacc agcgttgatt cttgctgggg
     1981 caacgatttg ggtttgccaa tcgaaagcag cattatatgc gcttgttatc ttcattatct
     2041 tagaaatttt acctaagaag gtttttcgaa atacacactt gtccttttgg atgtatgcag
     2101 cagtttcggt tctagcttta ccgatttctt attttgctgc aatgtcagac aaagttcact
     2161 tatttacagg acgagaagaa atttggcgca aattctatga aacattaggc gaaaaaacag
     2221 gacaaatatt tgtagggatg aaacctttct ttttccatag aggaaatcag attctaggta
     2281 atcataatac gtatcacgca ctcgtcaatc actatggatt gattggtttt gttctatcga
     2341 ttattctttt gcttagtttc ttatggttgc tcgtaagaaa acgtgagctg acaaatggac
     2401 aactaacatt cttgtgggct tttttagcga tcatgtgtca atcgttcatg gaagaaacat
     2461 taacgacaat cagttgggtg ccaattgtat tcttaatgtt agcaatggct acacaccaat
     2521 ataaaaccac cagataaatg aaatagaata gtaataagag aaaacacttt ttcgttgtga
     2581 aaaagtgttt tttgttttgt ctgaaaggag gcagatggat gaaaaaatgg ttatttggtt
     2641 ttttaggagt cgctttaatc gtcgtttgca gtgtgtttgg ctatgttagc taccaaaaac
     2701 atgaaggaga ggtgtttaag caaaatatag aaaaaaagat gcccgtagat caaatcaatg
     2761 cacacgcaaa gagttataag gaggatgcaa cgaacgtcaa taatgatatg tctttggggc
     2821 aaatgttgtc catacaaaaa gaagcaatcg aaatgggcgt caataaacaa gtatttgcac
     2881 aaattcagat tcctgcactt ggtttagcat tgccaatttt taaaggggca aatcaataca
     2941 ctttgagtct tggagcggct acttattttt atgaagatgc cgaaatgggt aaaggaaact
     3001 atgtcctagc aggtcataac atggaaatgc caggtgtttt attttctgat attcaaaagt
     3061 tgtcattagg ggaggtgatg gacttagtta gtaacgatgg cgtctatcgt tacaaggtaa
     3121 cgcgtaaatt tatcgtacct gagtacttta aattaatcga tggcgttcct gaagagaact
     3181 ctttcttgtc tttaccaaag aaaggagaga aacccttatt aacgttgttt acttgtgttt
     3241 atacgtcaca aggaaaagaa agatacgtgg tacagggaga gctacaataa caagaattta
     3301 atcaacgcga gtcgttgaaa tatgaaatga ggagagtaaa aaatggcaat aaatcggtat
     3361 gtaaaaaaag ctggaatgat tgttggaatg ttaggaatca ttgcaggctg ctttcagggg
     3421 tatcgagctt atgcagaaga tgtcacgcaa aaaacgccac cagaaagggt caatatcacg
     3481 gttcataaat taatgtacga tcaaagtacg caattgaacg ttgatattga cggaatcaaa
     3541 aatgatggtt atacgcacga tcaatatcct acaggtgtaa cgaaatacaa caaggcagat
     3601 tatggtgatg ttgagtttac gttaggaaat attacggatc aagtattacc gactgaagat
     3661 tctgatctaa ccaacgcgaa agtggacgaa atcgttaaag atgtagaaga caagggatct
     3721 aacagtgagt acgttaagaa tgcaaccaat aaaattactt cagctgtaga tgaaaatggt
     3781 gagatcactt ttgctgatca accagcctat gtcaattcca aagggaatgt atatgtggtt
     3841 tatgaaagta aatccgctgc tggattagtc acacaaaaag caaaaccaat ggttgtgatt
     3901 gcgccaatga cagacaacac aggatcagga tttttaaaag atattcattt gtatccaaag
     3961 aacattgttt ctaagttgag ttttgaatta acgaaatttg gtgacgatgg cacagctcaa
     4021 agcaaacaaa cacctttaaa aggggcaaaa tttgagttat acaagggcga acctggaaaa
     4081 ggaacaaaat taggagagct tgtatcggat gatcaaggaa agctgactgc aactgatttg
     4141 acgttaggaa aatactactt tgtggaagtt ccttcagaag ttgtagttgg atcagatcaa
     4201 gaaccaacag cagatcaata tttattaggc gcagacgctc gcaacgatgc gcacaataaa
     4261 ttaacctttg aaattacgaa tgatggcgtg acaagtgact taaaagcttc atacgtaaac
     4321 tataaagcac cagtgatcga taaaacagta acaaatggaa caggacaaga acattctttc
     4381 caaattggtg acgcagtaaa ttatcaagga acaattcata tcccaacaga cattgcaggc
     4441 ggagcagacg gtatcacagt aaacggagtg aaaagcgaaa cttctcctta cagtgtattt
     4501 aaatgggggg atacagcagg acaaggactt tcttatgtcg ctgctaaagc aaatatcaaa
     4561 gtaacaaata aagatggatc tgtggtatta aaagaaaata cagattataa aatccaaaat
     4621 tcagaaaatg gctttgtgat cgattttatc gtgaataatg gccaagtaag tgatactgta
     4681 gcaagtttac acggacaaga tcttcaaatg acttataaca tgtatgtaaa tgacagcgca
     4741 gctgttgcca atccattaac aaatagcgtg gatttcgttt ataacaacaa tccatttaat
     4801 caggaagaac accacgaaaa aacgaaagct gacgttgtga cttatggtgc aaaattctta
     4861 aaagtcgata gcggactatt tggaacagga atcaaagcaa caccgcttga aggcgcagaa
     4921 tttgctgcta aaaacgcaga aggaaaatat tatggtggat tagttgatac ggataaagac
     4981 ggtgtcaaag aagcagtatg ggtagacgat gtagcaaatg cagcgatcct aaaatcagat
     5041 aaagagggtc attttgaaat cactggttta actgaaggag attactcact ggaagaaaca
     5101 aaagctcctg aaaactatca aaaattaaca aaagagatct ctttcaaagt agacaaagat
     5161 tcatacaaag aagaaaaccg aatcacgatc aaaaataatc aaaaagcttc cgtaccaatg
     5221 actggtagca acggttttca aacgtatgta ttaatctctt gcttgttgct aggagcaggg
     5281 gcactttctg cagttgttta ctttaagaag aaagcctaga aggatcaaaa ccaatgatta
     5341 tcaggaagcc taagaaaaag cgaatcatgg gtaaatggat cattgctttc tggttacttt
     5401 cagctgtagg tgtcttactt ttgatgcctg ctgaagcgag cgtggcgaaa taccaacaaa
     5461 atcagcagat tgccgcaatc gatcgaacag gaacggcagc agaaacggat tcttctttgg
     5521 atgttgctaa gattgagtta ggcgatcctg ttggtattct tacaattcta agtatttctt
     5581 taaaactacc aatttatgac ggaacgtccg acaaaatttt agaaaatggt gtaggtatta
     5641 cggaaggaac tggtgatatt acaggaggaa acggtaaaaa tcctttaatc gcaggtcata
     5701 gtggacttta taaagataat ctttttgatg atttaccttc agtaaaaaag ggagaaaagt
     5761 tttatatcaa agttgatggt gagcagcacg cttatcaaat cgatcggatt gaggaagtgc
     5821 aaaaagacga actacaaaga aactttgtca cttacttaga accaaatccc aatgaagatc
     5881 gagtaacgct aatgacatgt acgcctaagg ggatcaacac acaccgtttc ctagtgtatg
     5941 ggaagcgagt aacctttaca aaatcagaat taaaagatga agaaaataag aaacaaaaat
     6001 tatcttggaa atggctttta ggaagtactg tttttctttc agtcatgatc attggttcgc
     6061 tatttgttta taaaaagaaa aaataaagga gggtaaccaa catgagaaat agaaaatggc
     6121 tatttgtttg tgcagccgct cttttttctt tcactgccta cacacagttg acgtttgcag
     6181 acagacaaga aagcacggat agcacagaac aaacaatcca aacgtcagat agcagcacga
     6241 ttcaaagcag cgatgaaacc gtcgattcgt caacagttga ttcttcagaa gaacctaaaa
     6301 ttgctgaaga cgatcaaata gtcaaacaga ccattcacgt tcaaaaaatt atttcttccg
     6361 aacaattaga caaccagggg caaaagcttg aaaaacaaga aggagtaaat ggcgcgaagt
     6421 tttctgttta tgatgtatcg gacattttac aaaagatgga tgttaaggat ctcactactg
     6481 accaaattga atcccaatta aaagatcgag tgaaaaaact atccagtgat caactgaagc
     6541 taatttctaa tggagaaaca aagacaattg atcaacaaac aggtgtcttt gaattctcgg
     6601 tagaagtaca ggcaaatcag aaacaagctt attatattgt caatgaatca agtcctgaaa
     6661 acatttctaa tagcgaggat attttgctat taacacctgt ttctgataaa aatggtgaat
     6721 tcttaaagga tgtgtggatt tatcctaaat cagaagcttc gcaacctaaa gaagaagtaa
     6781 aaaaaatcgt atctactggc gtaaagaaaa acttctttga gaattgttgg gattttgtta
     6841 ctcacttgtt ttctagagat taaggaagaa ataaaatgaa actgatcaaa ttattattat
     6901 tcaatttttc ttgtttaacc gcagtctttt tgtactgcgg tttattattt tctaaactat
     6961 ctattttgcc aagctaccaa ctatacctaa tgaggatttt aaacatacca gctgcttcca
     7021 tgccgctaga tattatggaa aagctcatta ggaatccatt atttactacg atcaatttga
     7081 tcgttattgt cggaatttca ctagtcattt ataaaaaaga ggggatgaag ggatgaattt
     7141 taaacactcg tggacaagac ggttaaaata tgtttttccc ataatgatga tgttaggtac
     7201 attgtttggg ttaaaaacag ccaatgtctt tgctgaaaaa gttattgtcg atccgtcaaa
     7261 tccaatccag aacgtaaaga ataattttat tattccaaaa gatgttccta atgcaaaaac
     7321 aaatattact gtaaacggag cgtcaaaagt ttacaaatat catgttgatg ccaacaaagg
     7381 tggttttaca gacgactacg taggattagt ggagggaaac aaaaatatac gctatccttc
     7441 tttccaaaaa gaatacggtg aaacaaacct tgttttagaa ggcgtaacaa ccaacaccaa
     7501 agtcaatatt gactatggaa aaatcggtac gtataacggg aaaaaagtca atatcaagct
     7561 agttctatct aatattcact tatactcgga tacgttgccg tggaatctac tagataacaa
     7621 ctatacaaaa actcattttc gagacgatgg ctataaaaat acgaatggtg caatgagtaa
     7681 atctaaaaaa agaacagtac tttggatctc agacaatctt ttctcaggaa ttgtttacca
     7741 ttcaacacaa atgaatgtgc agctagtagc cacatatgag gacggtagcc ccgttcaatt
     7801 ttcaggagat acatttatca gttttaactc tttgaaccct gcaggaggaa aaagcacgga
     7861 tcttaaagga gaatatgccc actatgacaa aatgaatacg acagattggt atgtcagaaa
     7921 agatacggtt ctttcagaat ttaaatcttt ctacaacaat ctgaacgtgg taggtggcca
     7981 cccaggagga agctctaagc tgacacaagc ggataatgat ttcaataatt tgcatgataa
     8041 attaggagat ccgaagtttg gtcaaggtac tgtgtccttt aaaatatctg aagcaaatcc
     8101 gacgtttgtg attggttctt ctaatgttca aacctggttt actttatctt ctgcgacaat
     8161 ctttagtgtt gttcctgatc aacctgaaaa aacaggggtt gataaaaatg gaaataacgt
     8221 gaacgataaa atgttgcaag taggagacac gattcaatat cgaatcaaac agaaggtgaa
     8281 tcgattagga gtggatttac tagcggttta cgatcgattt gagttaatcg ataatttacc
     8341 aaaagaagta aattacgtcg atgcacacgt tgaaagtggt acaaataaaa aattcgatgt
     8401 atctggtgaa gtgacctatg acaaaacaaa acaccaggta aaatatgcag cgaaagctga
     8461 tacattaaaa aatcgaatga agtataacgg cgaaacttac gaattagtga tcaatgtaaa
     8521 agtcaatgaa ttggccaatc aaaatagtgt agccaaaaat cagggaacgt cgatcattaa
     8581 taaagtagaa aaggatacaa atatcattac cgtttatttc cctaaaattc cagtgaaaga
     8641 agtacaacaa aatggaaaag atgtaaacgg acgaaatgac ggtaagaagg gtacgccgac
     8701 agctccttta aacgcaggat ctgaagtaca atatctagtc acacaaaaat ggcacacaaa
     8761 aggcgtagac gctgcgtcag atcactacaa acaatttagt attcaagatc caattgaagc
     8821 tcgtttgaca tataaagaag gttctgcgca agtaatagat aagagtaaag gaaaagatat
     8881 tacttctgaa ggcacactaa cctatgatag caattcaaga acgctgaagt gggaagcttc
     8941 cgctgacttc ttaagtaaca atcttttaga tggacgagaa attcagctga tatttacagc
     9001 taaaactcca ttacaatcag aaaaaaatat tgataaccaa gccgtagtag cagtagataa
     9061 tgtttctaat aaaacaaatg ttgtgacaat tggggttgat cctaacttgc cacaggtcat
     9121 tgttcctaaa acaggttcta cacatttagt aacgatttca gcggtcagct tactattact
     9181 tgtgttagca acttttagtt atgcggttct gagatacatt taaaataaaa aaacgaaaga
     9241 atgaataaaa tgaaaaagtt aataatagta gttacttcct tgattgccat gattgttatt
     9301 ttagtcggat gtagtaatga aaaaaataaa caaattaatc aagataatgg cgtattgaaa
     9361 tcaggaacta tgtggaaaga agaagtaggt ggtcttgttt ataatttgaa aattatagac
     9421 gagactacct gggaatactc tgagagtgta tggcatccag atcctgtaca aataacagtc
     9481 aagaggcaaa aagactataa aggtttagaa agatacaaaa tagtagattc agctggtgtt
     9541 agggaattta taaacaaatc tgattcttta tttattgttg ttccctatga gaagaatggc
     9601 gtaaaaaaaa taatttttct tggatctagc aaggatgaaa agcgaacgaa agagaaattg
     9661 attcacgatg gatcacaatc caataaatat aagttacaaa agactagcga gtgattgcta
     9721 gtctttttat ttgtcctgaa ggaggaatca cagtggcaaa agctaaaacg ccatttgaaa
     9781 aagccgcgtc taaaatctta gaacgccgcg gtgtatctga aacacagtgg aaacaagaag
     9841 tccttgaaaa agcacaattt gacctattac ggggaaaaga caaggactta gaaggatata
     9901 tctatcaacg tgaacgtgaa aagcttgttt tcgatgaaat tattaaacac taaaaggagc
     9961 gaacaatttt atgtttgaat caattacaat gaatttttta acacaaccga aagtagtagc
    10021 tgcggttgat atttttagag cattacaaac tgccgcaact agtttaaaaa acaatctgat
    10081 gatttttgct gctgctgcgg ccgttgcttc cattgttatt gggggtcttt tcttcctatt
    10141 tggacgaaga ggagctgaaa atgggaagat gcacgtaggc tatgtattga tgggggtagg
    10201 agttatttta gcagcagctt ctattgtggt ttcgttattt ggattgtttg gacaaacacc
    10261 tcaaggatta taagaaagta aaaaagtagg agtaagaagt agtcgatact ttttactcct
    10321 tttttatgaa aggagaatac tcatgtactt tacgattgca ggcaatacca aaacagataa
    10381 agagttaata aaaaaagcaa cgaaggaagt aggaaagcgt acttcttttt taccgaaaac
    10441 aattaaatat tctgtcattg aaacggaaga acagctacat gtgttaggga aagtactgga
    10501 acacgaaagt cgatcttctg ttaagttgac tctcacgtta catgacacag aaggaaaaat
    10561 agagaaagct ggtacagaat acgtttttgg cccactggat tatcaaattt cagaaggttt
    10621 ctatcctaca ttgatggatt taatccgcct tgatgtgttt aaagaaacgg atgaaactat
    10681 gagtgtggaa gagtcttatc gaaacgaaaa acttttacaa gttttagaag aagagttaga
    10741 gagcgaccaa agaaaagtga atcaagggag tgaagtcgaa gtaaatgaag aagtaccatg
    10801 ggaacgacca atatttccaa agaaggagtc aaaagaaaaa gagacagtct atgttgacga
    10861 acaagctgat attccgactc agaaatcgat atttgaggaa gagaacgatg tgatgggtca
    10921 attggaggta gatccctttg aagaaacaat ggaggatgaa gagacggccg aagtagaagt
    10981 tgatccagtt gaagcgaatg aagagtcaac atggactgaa ggggattctc aggaatatat
    11041 tgaaccactt atcagtgaag aagtagaaaa aaacgaaata gagatacaaa aggcaactgt
    11101 atttgattat attttggatc aatatccgcc agagcatgaa tggatgaaag aaaaaaataa
    11161 attattttta aatgagcttt attcgaaata tcaattaccc caaacctatc aagcattttt
    11221 agagagtaaa gaagaattaa tctcacaggg taaaggcaca cttttagaac agttagagtc
    11281 tgttcaatca acaaattggc atgagcttgc acaagaagat ttattagcca cttttgaaga
    11341 acgtcaacaa gaaacagatc aagaaataaa tgagtatgcg acggaacagt catctaattg
    11401 ggagagaaca aaagaggaac taaataaaga agaacaacga gtgattgaag aagaagtaca
    11461 aaaaattaaa gagcgatacg aaaagaaacg cgacaatgcg tattccttgt gtatagagaa
    11521 aattaataac tttactaaaa ctaatcaaga agctttatcg aaagaaaaag aaaacttgtt
    11581 aaaagaacgt ataaaagaac gaaaagaaga gttctaccga ggtttacgta cagataagct
    11641 aaagattagc aaagaattaa atgaacaact gaataaactt tatcaaacaa cgactgaagt
    11701 tcttatggaa agacacgggc agatccagca agaattacaa gcacaaattc caaaatggaa
    11761 aaaagagtat gaaattcaac aacaagaatt gaaagaacaa gaagaaaaac aacgacaaga
    11821 agaaaaagag cgcgaacaat tagaactaaa aaaacgtgag cagcatcttg cagaacaaaa
    11881 agtggcgata gaaaaacaac ggttagagca agaaaaggaa aaagaagcag ctgctcgtaa
    11941 ggaacgtcaa gaacaaatgg atacattgcg acaagcacag ttgaattatc tagcacaacc
    12001 tcaaccagta gctgctgttc aaacgccagt gaacaaccaa gcaaatttaa ctccttcacc
    12061 acagcgttcc tttaacggat ggatggtggg atgtattgca agtttaagct tgcttctagg
    12121 tggaggaaca gtatttgctt ttaatcatat caatcaatct tcacaggcag attctgtagc
    12181 cacaacggcg tcaatcaagg aagaagccca ggaacaagca agaaaagagt atgaacaaca
    12241 attggaagaa ttattgaatc gtaccaatca gtcaacagca gagtcaagta tggaaaatag
    12301 caaagagagt gatcctagta aggctaaaga aggatcaagc gattcaactg tacactcaaa
    12361 cacttccgaa agttcagaat caaatgaggt gaaataatgc gtattagaga aacaacgaga
    12421 cgaaaagaca aacgattcaa tttagaaaag aataggtatc tttctcattt ctatcgctat
    12481 actccttcag gagaagagct accagaaaaa catgacaaac gtatttctca aaagattttt
    12541 tatagtggct tagcttatct tcctttaaac tatgttgtta caagaatacc agaagcattt
    12601 catcgatttg agattattcc aggaagttta caaggagtga atatttttca gttacaagaa
    12661 atgccgcagt tattccattt tgattcaact ggtttttgga atcctttgac cccaacaaca
    12721 agtttaggca cacgtttagt tgtttctacg atttgtgttg ttccagctgt acttatggga
    12781 ttgaaaatgg acatgtggtt tcgtccgcta gcagatgggc aaaaaggaga taaccgatta
    12841 aaaacgttaa aggaaatcca acaaatttat ccgcaaatac cagaatcaaa gggaagtttt
    12901 cctggttatg gcggaatacc aattactcat tataaaaaat actggtatat tcagacggat
    12961 acagtaaata cttgtattgt tggtacttcc cgctcaggga aaggccagat agaagtttta
    13021 gcaaccattg acaatttgtc tcgtgcagaa agacaaagtt caatggttgt taatgatcca
    13081 aaaacagaat tatatgttgc tagtaaagat gaactagaag ctagagggta tgatgtgtat
    13141 gcatttaata tcaccgatcc actgcaatca atgagtgata atccattggc actcatcgtg
    13201 aaatactgga agcgaggaga catagacaca gcgacacagt taaccaatac tttcacgaat
    13261 acgatttatt atgatgccaa cgcttcagac aataaatact ttaacgaaaa tgcgcaaaaa
    13321 gctgtcaatg cgcttatttt tgcgttattg gaacaagcgg atcagacagg ggattactcc
    13381 aaattaacac cgaataatct cgtcgaactt ctttctgaga ttggtggttt taattaccaa
    13441 gatcctgata atgaattcaa gcagctcaat gctttagatg aatttatgaa tcagttacca
    13501 cctggaaaca tagcaaaaaa acaatatggg gcaacaaaaa ttggttctga taaagcgaaa
    13561 ggcaacattc tatcgacagc gatcacagga ctaaatccat ttacactgac gaaaattgcg
    13621 aaaatgactt ctcaatcaac cattgattat aagtccattg gttttccgaa gtatttggat
    13681 ctcaaactac acgagagtct gttaaaccag cgaattgttg tagagtttta tcatcaagga
    13741 aaaaaatttc atgaggaacg tgtcaaagta ggctatagag gtttttgtga aattaacttt
    13801 gattgtcatt tagaacaggg agatcatgtt tgcttaaaat acgatcatcg aggaaaagaa
    13861 tatgttgctt ggtatgagtt ttctcaaaga gtattgaaag acgaagaggg aaatatcgtt
    13921 tatcgaaaaa aacgaggaga aacccatttg ccagaattag aaaaagaagc cgttctaaca
    13981 ttagatgagg ataaaagtaa cttattagta gagtctattc ggatgcacta taccgataaa
    14041 ccaatggcta tttttatgct cacacctgat tatgatccat ctaaccatat cattgttagt
    14101 atttttctta gtcagttgta taaagaatta tctacgcaat gtgttaagac taaaggagat
    14161 aaatgtcacc gtaggattca ttttatttta gatgaatttg ggaatatgcc accaatggat
    14221 aatatggaag gaatcatgac agtcacagct ggtagaaaca tgttgtggga tttgtttatc
    14281 caatcctatc agcaacttta tgcgaagtat ggggaacaaa acgcagcgat tatcaaagaa
    14341 aattgtcaga cacatattta tattatgtcg acagacgata ataccataga agaattttcc
    14401 aaaaaagtgg ggaataagac ggttgaacaa gagaacagta ccatcaattc attaggtatg
    14461 aatactcata tcaatcgcaa tgttgattca gatcgcatct taactcctga aagaatttct
    14521 acttttttag aaggtgaaac gattgtactc gctcctttaa aacgacaaga tttgaaaggt
    14581 cataaaatac ggccgtatcc tatttttaat catggggaaa cgaatcttcc ttatgcttat
    14641 caatatattg aagatttcaa tccatcgtgg gatatcaatg atatagacat acattgtaca
    14701 catgcggact tggatcttaa ggctttacaa attgattacg attattttct acctgatatc
    14761 tatgcacgtc gactttatca caatatgcac gatcaaatag aagaggaagc taaagaaaac
    14821 atttttatta aaatcgttca atctttagac aactcaacgg cacaaaagtt acttattcaa
    14881 ttttatgaag agaagcaaat agatcgtttg caagaatacc ttgaaaaatt gcgtcaaaat
    14941 gaagaaatta cagaggttat aaggaaacga cttttgctag aagctgaaaa ggcggtgaaa
    15001 gaatgatcat tggaggaata ttttccggca ttgccgactg gtggtcaggc ttatttgggg
    15061 atggggatgc agatcccaaa accgtaacga aagtcttaca agattatggt aattatctgc
    15121 agtatcaaga tgtattcagt tggatttgta atactttttt atggggtttg attaaagggt
    15181 tatataatct caatacttta ctagaaaaaa caatttatca aagctttgat ttaaaagact
    15241 tattgaacgc cgctggtgtt aatgaactgt ttcaaagttt gattagtaag gtattggctc
    15301 ttttttgtgt cgtcacatta atttatttag gcttaaaatt ttttatgagt aaacatccac
    15361 caaaaatcaa aaatatcttg gttaatctat ttatggccat gattttgatt tttggtggta
    15421 gttctttaat cgatgaaggg ctaaatatta gtaaaaactt ttacggagac gtgactgcag
    15481 caaataaagc agataaaact ggttcacctg cttttcaaat tattcaaaat aatgtgattg
    15541 atgtgagtac gttactagaa aatgatccga acaaagtaga acacatacca acagacaaaa
    15601 gaaatgctct cacggcgaaa aattttaaaa cagcgaatat caatgggatt attacacctg
    15661 atcaagctaa gaaaatgtct gaatcaagtg atattagtac agtacaaaaa gatcggttaa
    15721 aggcattaca gtatcgacta gagttagacg ataatgggaa agaaatccct gttcaaatta
    15781 gtgatgaagg tttagcaaaa tatgtgtata cttcaggcta tcgccgatac attagtagtc
    15841 caggtattat tttagctggt gaatcttctt tgtcggtagc ctatttattt atcttgttta
    15901 cgattgttac ttgcattatt gagctggtat ttaaaaaatt ctatttagtg attgccgcgt
    15961 caacggactt tgagacagga caacggatga aaagtgctat agaagatatt tctcaatcct
    16021 tcttgttatt ggcatttacg attttagaat tacgaatcta tacattaatg ctttcaggta
    16081 tcggtgattt gcatgcggca ggaaagatca atggattctt gtatgttgtc gctttaattg
    16141 tattaaccat tgcgctattc aaaggctctc aatcagttac gaaaattttc ggcgttgata
    16201 cgagtctgaa aaacggcagc aattctcttc ttagcatgtt tgccttagga aatgttgcga
    16261 aaaatgtggg tagcggggct aaaaaccttg caagtgctgg taagagtggt ttaagcaatt
    16321 taaatgatat tcgtaaaaat ggatttggta atcgaaaaga tgttacccct gataacgggg
    16381 aagaacaatc agacgataaa gctacaactg tacctaatag taagaaaaca gtttccgaaa
    16441 tgttcgggaa agcgaaaaat ggtgtttcta aagccgcaga aggtcttggt tacgtcaatg
    16501 aacgtgggtt aaaaggaaca gctgaagatc ttacagaaaa agccaaagac accttagaag
    16561 agaaattaga cggcacgaga gctaaagaat tggctgaagc tgtgaagaat ccatccgaaa
    16621 cactagaaaa acaaaaagaa aaagcttcag aagtcaaaga aggactaaaa gatgcgtatg
    16681 gtgaaggaca agtcaatgca gcagtaaaag ctaatacaac aaccgaaaaa gaaaatcaag
    16741 aaggtgcagc gattccttca gccaaagatc accaagatga gttgcattct aacgaaaatt
    16801 cagaagaagg acaaaatggt caattaccaa aaacagatcc agaacaatat cgttataaat
    16861 ctaacattaa ttctgaaaat gaaaagcgca tttcagattt accaaaacga aatcaagaag
    16921 tacaaacgga tgatgattcc atcgatctgc caaatgataa tggggtcgaa gttggaactg
    16981 aaaaatcaac gaaaattggt ttacctaagg cacaaaattt accaatgaaa gatagtcgtt
    17041 tgaatcaatt caaggagaat gatcaaagct ttgttcacca atcaactgca ggtaatgttc
    17101 aaatgaaacc aagtcgtttg cctgaaaatg gaaatctgac aactgtttct tacaatttat
    17161 ctgaaagtgg ggagacaggg aatgcgtccg ttcaaaatgt tgtgacaaga gaagctgcac
    17221 cagaacctat tcaaagagtt cacacaggtt acaaaccagc aaatgtggca tttactgcac
    17281 caacaaaaat aaatgtgaca agagaaacaa aaaacaggaa caatgcattg aaagaacaac
    17341 tattgaggga tatcaaacag gatatcaaac cataaaaggc ctacaagtta ggcctttttt
    17401 ctatgtatga aaaggagaaa tcatttatgg ataaatatag taacatgaaa aaccctccaa
    17461 gatttagtgg agaatggaag tttttcgctt ttttcttttt agatctatta acgcttggtg
    17521 gctgcttttt ttgggcgaaa atggtcaata atcttgtcca cttaccactc ttttttgcac
    17581 tcttgaatta tggcttatgg attgcgatag cgttagtgat tgtttggcga ccctataata
    17641 acccaggtca acgacaaatt tttgcgatta tcgagtctat tttttttgcg gacaagaacc
    17701 attatcatgc gttagatcct aaccgaaatt atcatggtac gtataaggag gatgaataaa
    17761 tgcgagtcaa aggacaaaat tcagttgaaa ggaaatccat tttgcagttt ggaaaaccag
    17821 aagagcgctc tatcttggac ttatttccgt ataaatcctg tacagaagag ggagtcttaa
    17881 ttactagaga agatcatttt caacgttatt atcgtgtagt ttctacagac gtggaaggat
    17941 taaatgaaca agagaaacta gaacgaatga atcagttgac caccgtcatg cgtacgtatg
    18001 tgccaacaat taagttagtt agtttgacca cagagacgga tctaacggaa caaatcgtgc
    18061 aaaagcggca attattagat aaaaatcgta tggaacagtc cttaggaaga aatctacaac
    18121 gattaaaaaa atatgaaaag aaattagtcg aagaaatcca ggaattgaaa cgagcagaac
    18181 aagaacgtcc tgacttaagc ttctttttcg tcattgaagg aaagacaatc aaggatttac
    18241 aaaccagaaa ccgtcagtta atgcgatcta gtggcatttt agggttaaaa ccactctaca
    18301 aaaaagaatt gatcaagatt ctgtatcgaa tgaacaatat gaatgatgag taggaatgga
    18361 gaagagagaa tgaaatatcc gttgatatgg ttagaaaaag atgttccgaa ggaagagacc
    18421 actagaaaat ttcctcacac tttaagcctg ggtaagttgg gaaaagggca atcttttaac
    18481 caagtaaaga atcaaacaag aagaggtgac tgtacatgtt agaagcaatt aaaacagctt
    18541 tttcaccaca aaatgatcaa aaagtacttg atccattaaa gcaactagga aatcgggaaa
    18601 tagaaattgt aaaatccaaa gggtatgatt tagatttttt aaaacaagtg atgccacaag
    18661 gtgggttgaa ttttgatgaa gaatatgtga cctatggaaa tggttattca cgatgtgtga
    18721 cagtttatca ctacacaaaa aatcctactc ttttttggtt ggccaatctc atgaacaatc
    18781 ctcatacagt ggccacactc gatgttagca cagatgaaaa gcaaaaagtg attgatcaaa
    18841 tcaatcgtgc cttagatgaa ttaaatgatc gatcagataa tgaacgaaaa gcgactgacc
    18901 gaaataaaag cgcggaagaa tacctggaac tagcggaata tgctagaaaa ttgacttcta
    18961 atggggaaat ttctaagcaa gtcaaagtga gagtacatgt ttacggaaac acgattcaag
    19021 aagtagatga acgagcgcag gaactgatcg aaaatctcaa agggatggat tatcgtgcgg
    19081 tgacttatct gcataaaacc aaacgagatt ggcaatcgat gtttaccatg ttcgatgaac
    19141 aagctgaatg gttcggaaat atcaaagggc aatcactacc atcgttaaac attggcggag
    19201 gtttcccgtt ccaccaccaa acgctaaaag atccaggagg gacacaatat ggggaaacca
    19261 tgacaggcgg cccatttgtc tggaatgcca cgtataaaaa tagtgtacgt ttatctacca
    19321 ataccttgct tctaggaatg atgggagctg gtaaatcgac cgttcttaaa atgatcgcgg
    19381 aagcccattt agctgcagga gactttattt ggggctttga aaagggaaaa gactttattc
    19441 ctttcttaaa ggaatataac ggtattatgg tgcgtttaga cggatctgac gggatgatca
    19501 atcctttaga gatctttgcc acacggacgt atgatgaagc atccagttta tatgacgatg
    19561 gttcagtcaa agatttgaag atcaatgaag cagcgtccta tcaaacgcac ttagacaaag
    19621 tagtctatca ggtacagtta gtgagtcctc agctaaaagg aacgatgaaa gcagaattca
    19681 agacctactt gaatcgtttt tatgaagagt atggaacagt accacgcggt tttacttcct
    19741 caaattcgcg ttcaaatact gatacgcaag tcacagggaa agatccagaa gcttatccga
    19801 cgttcaaaga atttttagcc tttttaggac aactggaact accaggggct tcccaagaga
    19861 aaaagaatcg gaaagaagaa atggagtcta tcgtggaatc cttatgtgag acttatggca
    19921 tgatttttga tggtcatagt acgattcgac accttgacca acaacagttg gtcttttttg
    19981 acattgactc tattacaggc ctagatcgag gggtacaaca atgtcagatg tacatggcca
    20041 tgacgttgat ttggaatcag gcattgattc aaggacgaag acaacgacgc ttaattaaag
    20101 aaaaacaaat ggaagaacaa gacttcaaac gcttcttggc gatgattgat gagtgccata
    20161 atgcgattaa tccagatttc attgaaacgg taaattatgt cacaaacttc caacgagaaa
    20221 tgcgtaaagt agaagcaatg actgttttag ctacacaatc cccacaagaa atggtgccag
    20281 aaaatatgtc ttctgataac ttctcgaaac tgaagaaagt ctttgaattt tcttctacga
    20341 agatctttat gcgtatggat gaatctattt tacgtcatat agaaggatta gttggtaaat
    20401 caatgacgaa ctcagaatta gaatccattc ctcaacaaaa tcaaggagac gctgtgatca
    20461 attttggctc aaaagaaacc attcgtgttc attttagtcc gaacaaacgt caattaaaat
    20521 tgtttgatgg aggaaaataa tggaaaacca aaatgaaagt ttaatcaaac agtatgttaa
    20581 gcgtcgtgca aagcggcgct tatttttgtg ggtgtttggt acttctgcag gtttgattac
    20641 tattttgatc actgtgttcg tgaccctatt tctaatactt gcggcgggct cgattgataa
    20701 ttcggattca gattcaagca gtggtggcga agcttttaca ggagaatatt cggaaggctt
    20761 accgatttat aaagaaatca aaggaagagg ccctttttct gatgagattg cgcaatatgc
    20821 cgtaggtgca gcagtgaaat ataaattatt accaagtgtg atcctttcgc aatacggtta
    20881 cgaatcagcg tttggtacat cggcgtccgc aagaaatgat ctcaactatt ttgggattac
    20941 ttggtttgat ggttgtctgt ttcctaaagg aactgcacga ggaattggtg gcattgaagg
    21001 tggctggtac atgaagtttc ccaactcaaa agctgcattt tcctattacg gatttatggt
    21061 agccacacaa tccaatttta atgcttgtgt aggaaataaa agccctggcg caagcttatt
    21121 gatcttagga cgaggcggtt atgccgctgc aggaattacg gaagatagtc cgtattatac
    21181 aggttgtatg tcaattatca cttctaataa attaaccgaa tatgatgaat tcgccatcaa
    21241 acattggggt gaaggtggca ataacaacgg cacgattact ggtgaatgga cgaatccatt
    21301 ccctggcagc agtttagata aaagttcctt cagcggtggt caattatttg gaacgaatcc
    21361 aggcggtgaa ttccgtccga acggcttcca tgatggatta gattttggtt cagttgatca
    21421 tccaggaagt gagattcatg cggttcatgg cggaaaagtc gtgtacgttg gcaatcctgg
    21481 tatttcaggt ttgggcgcgt gtgtgatcgt gattaattac gatggcttga atatggtgta
    21541 tcaagaattt gcaaatagta caggaaattc tcgagtgaaa gtaggcgatc aagtgaaagt
    21601 tggtcaagta attgggatac gagatacagc acacttgcat ttaggattta ctcgaatgga
    21661 ttggcgtcaa gcacaaggac atgcattcat tgatgatggt acatggatcg atccgttacc
    21721 atttttgaat agcagtaaaa aatagatcag gagaaaaaat atggaaaata aaacgttaaa
    21781 aatcgtctta acagctgcaa ttagcgttag tttaatcggc aatattgcgt tgttttggca
    21841 gctgaaagag gaacaagcag caaataccta taaaattgaa gaagtggcta aaaacgcgtc
    21901 tgagaagctc aaaaaaaatt cctctgaggc acaggcgaag atcgacaagt taaatcaaac
    21961 catcaatgag aaaaaccaag aaatcgatca gctgaagcaa caagatggca caaaagcaaa
    22021 agaggaagta actgaagcac aaagaaagac ggcagaagag ttcggtcaat tggccattga
    22081 taaatcatta agcagaaatg aattaacgga aaaactaaaa gatgtcgcaa cccaagaagt
    22141 gatcgacaaa ttaagtccta cagacgatga tcaccaacat gatgattacg gaagttactc
    22201 ctttacatta ggtgacgtgc aaacttacgc tcaaacaagc agtgtaaaag aggaacaaaa
    22261 ttttgtcgta tttgttgatt atacaatcgg caatccgcaa ttcaaagatg tcaaaccaca
    22321 aaaaataaaa ggtggattaa ctgtcactga taaacaagta gatggtcaat ggaaagtcat
    22381 agactttagt tatttcactc gttaggagga agaaaatgag taagaaaaaa ggagaaagac
    22441 aacgtttcaa aaaacgaaaa agttatcttc aatggctggg aatctttatg attctcggct
    22501 ttttgattct tgctagtccg atttatacga atcagaaggt agatatacca gatgaggtaa
    22561 gcacaaacgc atttttaaac acgaaggaac tgacgatggt ttcaaaagaa aaaggagcga
    22621 accagcaatt agtttttgaa ttttcgatcg acgatgaaga tcaaagctta ttaaaagaac
    22681 tggctaatct taattatcgt gtagaagtaa agacagctaa aggggattac caagcaatac
    22741 gagccaaagt gatcaaggtg tctgatgatt attttgcagt gaagttagca catgtaccag
    22801 aagaatatat cgccatgcgt ttaaccatta ttcctgaaaa aattgatcca aaagtggata
    22861 tgcaagaacc acaagatctg atttattacg tgcacgaaga taaggttaaa gatcaagtga
    22921 aagatgaaga ttatgaacaa cacgcgatca attacaaagt gaaaggatac aagaaagaac
    22981 aaaaagcagc tcaaaaacaa atggaatctt tccaagcaac cattgatttg aatgaagaat
    23041 tagtgaagaa gctaaaagag caattgcctt atcaagtcgc agatgatcag gaaaatactg
    23101 aaaacaagat taatagctac cagcaagaaa ttgaaacatc gaaaacgcaa ctgaaagatc
    23161 aagaagagat cattcaaaaa cttcaagaaa aaattgatcg tatgacaaaa gaaaagattt
    23221 agaaggacag gtggagtgaa aaaatgaagc gaacaaactt ggctgacaaa gatactttcg
    23281 ctgagcagaa agtattgatt aaagcctatc tcaaagttgt aaaagctaaa gaaatatgtc
    23341 gagaagtgaa tttatctaac acaacaatat ctgagttgaa gaatggtcga aagaatttag
    23401 atactttaaa attcagatca tttgaagctc tatatatagc tgcaaaaaaa tattttacag
    23461 ctgataacaa ataaaaaaca ggagtatttt atgtgaaaaa agtatataaa aaatgcttat
    23521 gaatcagcta tatcacctta accatttgtt aatgagatgg gagaaaacat taaccacgat
    23581 tctaacgcaa acatcaagca cataaaacat ttaacactcc tcctttctgg ctgaagattt
    23641 caaccaaaca ggaagacagc gtatcaatta tagcatacac tttttcttaa attcattttt
    23701 catatgacaa aatatttcct tctaatcgac aaagttagaa ggatttttta ttgtctaaat
    23761 acacaaataa ccttaatttt taaagagcat aaggaaacgt gatatcactt tctcacgaaa
    23821 ggtgttaggt aggctgtgcc taccacgttt ctaagaaaga taaatgatat caaaattttg
    23881 gatttgtgtg tagatttgtg ggtaggatga aagcgaatgt gggcagtaaa ataagcgttt
    23941 gtgtgtagca aaatcaaaaa atgtgtaggg atatgtgtag ctacacatat ccctacacat
    24001 aataaatttg gaggaaaata tggacttatt aattagaaat attgaagaaa agtatattaa
    24061 taaaattgac aaacgttgtg aagaacttac ggtcaagact ggcaaaaaat ggagtcgaaa
    24121 tcaataccta aaagttttga tcgaaaatga ttttgatcac gctcttctga attataaaaa
    24181 agaccaattt gatcggttgt tagaaaaatt tgtggatatt caaacttata atacgaaaac
    24241 tttagaagaa tatattgcaa caaataatca attaattggt ttgttaattg aataataaaa
    24301 atagtattgt gaatttataa aaggaggaaa tcaattttgg caaaagcaac aagaaaacat
    24361 gtatatcttt acgatatgca tatcgaagta cttgatgaaa taatttctac tcatgaagat
    24421 atatctaatt atagtgaagc agtcagacat ttgtgtatga tgtatgatcc aaaaatcgaa
    24481 gaaaaaataa atccaattca aattaaattg aatgcaatgg gaaaagaaat ttctatttta
    24541 accgaaatgg tttcagagtt tgcggatctt catttgaaag atacaggaat actaattggt
    24601 acaaattcaa cggtttacca agaagcaaaa gaacgtgtgg aaggaaaaat taaatccaat
    24661 aaaaccaaaa aatattcccc tcagttgaag aaacctgtga atgaatctgt tcatgctaga
    24721 gtagatccat ttgatccaac gaagattcta aaaagataaa agtagaaggg aaacatgatg
    24781 aataaatcgc ctgcagtcat tctcacttgt caatttacct tgcccaataa aaaatctttt
    24841 tcaacataca ttgattatat gacaagagaa aaagcgctgg aagaaaagga acgacgcacg
    24901 ccggacgaag aacaggaact gcaacgaatc aagaatgctt tagaggattt ttatattcct
    24961 gaaggagaaa ctttttcgga gagtaagaca gataaagaat tcagtgaaac gtcgaatgaa
    25021 gctcaatcgt tgatggaaca tggaatcaat tttgacaagt tagaggaaca agattttacc
    25081 aaatatcttt cttatatgac ccgtcactat gcgttagaac aaaagaaaga actgacgcaa
    25141 agggaacaaa aagaatacca acggttgaac caagcaatga aaaaatatca aacagagcca
    25201 cataaaaaag cttcaggaaa tcttcctgga gttttttcta tggcttcaga cgaagtgaaa
    25261 ggaagtgatc tgaaggagat caaacaaatc ttccaaagag ggcaacaaaa aggctcaatc
    25321 atttatcaag atgttgtctc tcacgacaat tcgtatcttg aaaaaatggg cttgtacgat
    25381 cccaaaacag ataccttaga tgaagaagga ttaaaagcag ctggaagaaa aatgatggag
    25441 acattattcg agaaagaaca attgaatgaa acaggttact ggatggcaac gattcaccgt
    25501 aacactaagc atatccatat tcattttgca gttgttgaaa aagaaaatac gcgtaaacct
    25561 tacacggagg ttgaaaatgg tgtgagttat atcgtaccga aaggtaagag aagacaagca
    25621 acattagacg caatgaagac caattatgta catgagttag aacgtttttc ttatgaaaag
    25681 gatcgaatga ttggtatgga gaaacgaaat ttattgacgc ggaaaagtga tttgcgtaac
    25741 accttaacaa aagtggtaaa agagccagcg cgttacgatc gacacgcaat gaacttatta
    25801 aatgaagtat ataaaaccct acctgacaaa cgttcggaat ggcattatgg ggatgaaaaa
    25861 cgaaccaaac tttcaccata cacaagagag aaactcgatg agttaaccaa atatgtgtta
    25921 acaaaagaac ctgaatatca agaatatata cagatttcaa aatcattgaa agaagaagca
    25981 aaaagtcttt atggggaaag caagagagaa tcaaaggatg cagaaaaaaa tgctctcttt
    26041 gatttgaaga agcgcacagg aaatgccatt ctaacagaac tgaagaaaca ggatagtcaa
    26101 ataaaacctt taatagaaag tatggatcag atgcaatcta tttacaatga acgatccttt
    26161 cgaacgctta aacagttacc aacgaatgaa tacaaatata gttacgaaga attcatgaag
    26221 cgcaggaaac aattccaaca aagagttgtc acgcaacgga gtttgcgtca attaaatcga
    26281 acgattaatg cccatgaaga aaaataccac gcaagtaaag cctacgaaga gcaacaacga
    26341 agaattcaaa tggaacaaga aagacagtaa agacagtagg aggaatagca atgaaacaat
    26401 atttagatca atggaaagtc atagaaggat cattaagaga agaacgaatc gaacaacttc
    26461 ccgattgttt agaaaaagag catttgtttc agataagaga aatgttgaga aacgaacagt
    26521 ttgatccaaa tcaattttta gtcgttgagt acccagctac tggtgtgtac tgttgtaatc
    26581 atgtgaaggg tgaaaaatat tttatcattc aagaatatga gggcaagtta gcgccttatt
    26641 atactacttg ggaaatgaat gaagagggga tcaataactt cccgtgtaaa agcattgaag
    26701 agtctatttc actcacagaa tgttagttgt taagtgaata aaagaagtaa aagagtcctg
    26761 aacataattt gtccaggact ctttttttca atgaattgtt ttccgccaat tcattgagtg
    26821 gtgcgatttc cgtctacatt atatcaaaag aaaggaggaa aaagaaatgg ctcattcaac
    26881 gattggagtt gttgttgaaa aaagcagaga caatctcgtt tttgtgacag aaattcaaac
    26941 aggtagatct tttgtcgtca cagacaaagc ggcaaaagct tatcgaagtg gcgatatttt
    27001 agcgttaaat ctgattacaa aaacgttcgt tgatgcagta gaaaattatc catt
//
LOCUS       DAPBAF010000041        26574 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.041, whole genome shotgun sequence.
ACCESSION   DAPBAF010000041 DAPBAF010000000
VERSION     DAPBAF010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 26574)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26574)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26574
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.041"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(324..893)
                     /locus_tag="RD451_002053"
     CDS             complement(324..893)
                     /locus_tag="RD451_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HDT7567288.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYETLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(967..2256)
                     /locus_tag="RD451_002054"
     CDS             complement(967..2256)
                     /locus_tag="RD451_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567289.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFCFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESENKSKLTKVLYQEWLRYVI
                     GIHDRLIEEVRYYQETLEKFPNSKDKLYQFRLAIQQAFAHPAVEWGMLLLKTLQERGY
                     LDVHPPEVKIVFFFRYEHQEARRLAGVLNKTLRHRKRISIHVCTRNKPPRYADLVITD
                     HFFPLDHNEDQKTYLYHPSFGIERLLTDINYWLGKNR"
     gene            2610..3458
                     /locus_tag="RD451_002055"
     CDS             2610..3458
                     /locus_tag="RD451_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HDT7567290.1"
                     /translation="MIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGTFSRVQCTPD
                     LLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLEAMAENHATI
                     DNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDDELLLLLDKF
                     EKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAIQLGISPRGS
                     LSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKKQIIHTLVAQ
                     IPVPVR"
     gene            3472..4545
                     /locus_tag="RD451_002056"
     CDS             3472..4545
                     /locus_tag="RD451_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HDT7567291.1"
                     /translation="MEKIKDYFINFVLFLVYFIIVLFALVFNNSLGWFLLAFFTLYVS
                     WSLISLSSFLKKLSVTCTLQPLVYRKKSMQVIFSIAKKRTFSLPLPRLQIGFPAIFAE
                     KKQEILILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFRKSAKREISFPVTVL
                     PAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNRIDWKLSAHTQEWLY
                     REYDYQEEECSPLFCFWGSHSPKFEPLLDLYFSLWHLRKEKQPELLILGNRAFHGKDP
                     GHTYFASLEAGDEKAFFAHLKKYAKKQIVLFVPENSPEVSEAIETLSKDRTVYLVYFV
                     EKQLMVQEKDKICSLPGGEWIDD"
     gene            4535..6706
                     /locus_tag="RD451_002057"
     CDS             4535..6706
                     /locus_tag="RD451_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HDT7567292.1"
                     /translation="MTIKWEKWLCGVYSFVILSVGAPIFVVANQLQNSYLLILTIGVL
                     CLIVCCIPKKWVRLLLSLPVMIGCLFLYFPSKTFSLLWILQFFSSVTEEFFHLSQGKL
                     YYLPEKTAFFLIMLLIYLFITLTVDYDYLYAPFLSLMAYFMMLTVFREKDLLYEMIAV
                     VTVLFVYLAARQFFSMRLLSGNTRFQSLTTVLLICFLTISAILPLYLPKVHQSLEETS
                     EPIREYLNDEGLYDTLHEYQLTGSARTGFSENDEQLGGPLYDNGEVVFTANQKGNGYW
                     KIENKNHYTGSGWIEDQDAPIQPIQEFPVDITSYQTVMEDKENITLTLKKQAFLPYPY
                     GNTTLTDFSLASGQTLYYLPESQRFIPVPNESTRSATLQTERLVFTREELKSSQLKAD
                     DLENQQTNLQLPKSLPKRIEDLAVELTKNEATLIRKVEAVEQYLKTSGNFRYSKTDTG
                     HTPKEHDYVDYFLFDSKVGYCDNFSTSMVVLLRTLGIPARWTKGFTNGLRTGTDNQGN
                     EEYSILNSHAHSWPEVYFPGFGWLPFEPTPSFANPMGSQPVAETTETVQPAIEQPNES
                     ENMAETISSERSEVIPSEETTLTPAYKIVLFSLGVCLYVLLFFLLLFRKSLRWTSYLI
                     YLHFFASTNTIAYQKLLNHLETLVPRKPAESLQEYSLRIEQEFKLDLRFIRLTTQYEA
                     EIYGRQADPVNFDKKTYLEITHIIRKTVYKKVLTKGSRFKK"
     gene            complement(6818..8974)
                     /gene="copB"
                     /locus_tag="RD451_002058"
     CDS             complement(6818..8974)
                     /gene="copB"
                     /locus_tag="RD451_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HDT7567293.1"
                     /translation="MHMGHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHMGHNHG
                     DIANSKQMDHSMHMDHDHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGMEFPFQ
                     VTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYIYSVYS
                     FIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPESVKRL
                     TKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGIKKQAN
                     DKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAKWLFYV
                     ALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAAKNGLL
                     LKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGALEANAN
                     HPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKNQQVKIVNEKEVERLGLNVEQ
                     ALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVMLTGDNK
                     NAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLARASIGM
                     AIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILAIPLAA
                     GILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIK"
     gene            complement(9117..11303)
                     /locus_tag="RD451_002059"
     CDS             complement(9117..11303)
                     /locus_tag="RD451_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HDT7567294.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKSKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGLIAVADQIKLEAKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMSSSLASIAQTIELSRVTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLSLNRHMKK"
     gene            complement(11303..11512)
                     /gene="copZ"
                     /locus_tag="RD451_002060"
     CDS             complement(11303..11512)
                     /gene="copZ"
                     /locus_tag="RD451_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HDT7567295.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            complement(11525..11965)
                     /locus_tag="RD451_002061"
     CDS             complement(11525..11965)
                     /locus_tag="RD451_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HDT7567296.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYHPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            complement(12039..12512)
                     /locus_tag="RD451_002062"
     CDS             complement(12039..12512)
                     /locus_tag="RD451_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation family protein"
                     /protein_id="HDT7567297.1"
                     /translation="MGRENRPSQGRSKKSPAFRIQAKKWFLQEQQSFMVSNPSWIVEG
                     NYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLKRKINKKSRPDMPESFSEKLNRK
                     YLEFLSFIWHFEGNNEPKIQQLIQVANARNKLIILKTRREKQEFLTKLKIESKNN"
     gene            complement(12822..14288)
                     /locus_tag="RD451_002063"
     CDS             complement(12822..14288)
                     /locus_tag="RD451_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDT7567298.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
     gene            complement(14599..16683)
                     /gene="cadA"
                     /locus_tag="RD451_002064"
     CDS             complement(14599..16683)
                     /gene="cadA"
                     /locus_tag="RD451_002064"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HDT7567299.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQETKKVVKELEPDVKVTEIDKEKVSEHGNEKKRNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTAEGLMTVNPEDVLIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     RAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDPTGIDPKKFMQYVASAEQFSTHPIAQSVLEGYAGPLL
                     PTANIQEFAGEGILAEVDGKQVLVGNHKLMERFEISFPSSQEIGTLLYLAIDQSYSGY
                     LVIADTLKEDAVDALVQLKQAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDK
                     VQRLEEILQSNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQP
                     SKIAEAIHLAKKTLKIVKQNIVFAIGIKILVLSLGAFGFASMGDAVFADVGVTVLAVL
                     NAMRSLHVKNKR"
     gene            complement(17207..17566)
                     /locus_tag="RD451_002065"
     CDS             complement(17207..17566)
                     /locus_tag="RD451_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HDT7567300.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            complement(17596..17937)
                     /locus_tag="RD451_002066"
     CDS             complement(17596..17937)
                     /locus_tag="RD451_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567301.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERLDQRPSGKLIQHTLVTKENTEEIQKKFAEYLMLEAK
                     KRRIKSIFAQF"
     gene            complement(17934..18608)
                     /locus_tag="RD451_002067"
     CDS             complement(17934..18608)
                     /locus_tag="RD451_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HDT7567302.1"
                     /translation="MKKRILFIGDSITDAGRYRAEATDLGKGYPLLIAGKLISQYPTM
                     EFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTAEICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIAYGFSKYTREDGVHPTIGGHEIIAQSWIDAIVAVDFFSGDKNE
                     RKKSEK"
     gene            complement(19403..20701)
                     /gene="asnS"
                     /locus_tag="RD451_002068"
     CDS             complement(19403..20701)
                     /gene="asnS"
                     /locus_tag="RD451_002068"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HDT7567303.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKITFLQLRDGTAFF
                     QGVVVKSEVSEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            complement(20741..21931)
                     /locus_tag="RD451_002069"
     CDS             complement(20741..21931)
                     /locus_tag="RD451_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDT7567304.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNSEIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYPLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            complement(21952..22479)
                     /locus_tag="RD451_002070"
     CDS             complement(21952..22479)
                     /locus_tag="RD451_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HDT7567305.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEEADHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            complement(22526..25315)
                     /locus_tag="RD451_002071"
     CDS             complement(22526..25315)
                     /locus_tag="RD451_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HDT7567306.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGIGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLIQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            complement(25462..25662)
                     /locus_tag="RD451_002072"
     CDS             complement(25462..25662)
                     /locus_tag="RD451_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDT7567307.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            complement(26114..26434)
                     /locus_tag="RD451_002073"
     CDS             complement(26114..26434)
                     /locus_tag="RD451_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567308.1"
                     /translation="MKKRLLWCLLFLSLSLTSQPVFAEETQRSPITGTRLYKNVYVQT
                     TDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
BASE COUNT         7471 a         5626 c         4665 g         8812 t
ORIGIN      
        1 gtcaaggaca atcggaatag catacggaaa gaagttctgc accttataaa atttgtcaaa
       61 aaaactgttg ccattccaag tgaaaaaaag atcaatgaat caactagaaa actatataga
      121 agagcaaata aaaaagcact caaattgagt gcttttttaa gctcactatc actaaaacta
      181 tcactaattt tatttataag cgaacatgtt tctatcactg attttttaaa tctagcgaaa
      241 aacccttatc ttaaaggcgt tcgttcaatt ctttggcaag gtcttcaaag cctggcttgc
      301 ctagaagtgc gaacatggtt ttcttatagc tcatgtagaa aaattttctt gatgatgatt
      361 ttatccatca attgagattg actgttttgc tctcctatga tttcagctat gattgtccga
      421 ttttgcggtt ttcttcttaa ctggtagttg attttcccag tttccatcaa ctcgctaagc
      481 atatccacga ctccgccaaa tccggtcttt ttcgtaataa aacctagtgc taccattcgt
      541 tcatctagat tttttgctgt aatcgtcaca ccagtaatga gcgagtgctg taatgtttgg
      601 gccagctctt ccatcccttc agcattggat acgacggaag ctgttttgtt aataggttct
      661 tcgtttattt cttttggttc tttcctctcc actttcactg tttgacgaag gacatctagt
      721 tcttgcaaga gcgtttcgta ttgttcttgg gtcagcatca cgccagctac tttttcacga
      781 ttaaatatat atacgccagt tcccgcgtct cgcgcttgag caaatacatc catcggcgat
      841 cgtttcactt ctgtgatcga agatgtggga acttctaatt tctttaattc caatggattt
      901 cctcctttac taatcgcttt ttattatagc acagactgac ttgttttgat cttttttcca
      961 aaggttttat cggtttttgc ctaaccagta attgatatcg gtaagaagtc tttcgatacc
     1021 aaatgaagga tggtacagat acgttttttg atcttcgtta tggtctagtg gaaaaaaatg
     1081 atcggtgatc actagatctg cataccgagg cggcttattt cgagtacata catgtataga
     1141 gatccgtttt cgatgtctta gcgttttgtt cagtacccca gcaagtcttc ttgcttcttg
     1201 gtgttcatag cgaaaaaaaa agacgatttt cacttcagga gggtggacat ctaaataccc
     1261 tcgttcctgg agtgttttca gtaaaagcat cccccactct actgcggggt gtgcaaatgc
     1321 ttgttggatc gctagccgaa attgatatag tttatctttg gaattgggaa atttttctaa
     1381 tgtttcctga taataacgaa cttcttctat cagccggtca tggataccaa ttacgtaacg
     1441 aagccattct tggtaaagta cttttgtcag ctttgatttg ttttcgctct caaattcgct
     1501 attcagccaa aacagcgaat caagcttttc agtcacaatc gtcaatttcc gatagtcttg
     1561 tgtctcttct atccgtttcc accgcttttc agtaatctgg ttacagctca agcgcaaaat
     1621 tgctagataa tttttttctt ttattggcaa aatctgctct tctctaaata gcaattcagg
     1681 aaacaattca aagaatagtg ttcgactgtc tcctaaaatc tcgatttctg ccggatcctt
     1741 tctttgcttc aataattgga tgaacatctc agaaaaggac tgctctccat catctgcaaa
     1801 aaaatgcgga aaatctttca aaaagcaaaa cagcagatat cttacttttc tttctgaacc
     1861 aaagatctgt gcttttttat aagaaaaaga aaggtggtac tcgccaaacc actttctcaa
     1921 tcgctcttgc gtagaacgat cgtacttctg ctcgtaaggt tcattcaata gcagattttt
     1981 cagtaaacaa aacgggggtg attggatcag aaaaacaaac aagagataag gttcgctata
     2041 tccttgatca taaactaact gaacggtttt cttatgaaga atcagctgga tgggacagtc
     2101 gctttccgcc aaacgtttca gatgccgatc cactgtttta acatcgattt tcagttcttc
     2161 agctaaatca gcttttcgcc agatcaaatc tttcattaga ttgattagtg aaaataaatt
     2221 ctgtgcattt tttgataata gtttttgcca tctcatcgat catttctcac ctgatttcta
     2281 aacatattgt ttgatcaaaa tgggttcact cctaaaaaga taaaaaactc cctttctatt
     2341 tatttaaata cgcaaatttt cctcattatt tttaatttta ctcaatttaa tcgtattctc
     2401 atttcaaaac gaatgtactt taaaaaaaca taataaaatc actttgcttg taggatgtat
     2461 tcccttccat tacaatgaaa taaatagcaa ttttatgaga aggtgatgtg aaaatggaag
     2521 aaaaaatcga agaatccaaa caaaaaatcg atcagttgat acaagaatta gaaaaagcgg
     2581 tcatcggcaa acgttcaact atccaattga tgatcgtggc cctattagca ggtggtcatg
     2641 tcttattcga agatattccc ggtgtaggta aaacgttact ggtcaaagca ctagcaaaag
     2701 ctgtacaggg aaccttcagc agagtccaat gtactcctga tctgctgcct agtgatattc
     2761 ttggtttttc cgtatacaat tcacaatcaa aagagtttga atttcgtccg ggaccgatct
     2821 ttaccacgat cttgttggca gatgagatca atcgcacgac tcctcgtact cagtcagcac
     2881 ttttagaagc aatggccgag aatcatgcaa cgatcgacaa caatacatac cctctagaca
     2941 atcatttttt tgtcttagct acgcaaaatc caatcgagta tgaaggaaca tatcctttgc
     3001 cggaagcaca gctcgatcgt tttttattcc gactacaaat cggttatcct tcttttgatg
     3061 acgaactttt gctactttta gataaattcg aaaaagtgtt ggataactta aatgaagtat
     3121 tgaacagtta tgaaatagaa gaaataaaaa caaatgtggc gaatgtcttt gtcagtcccg
     3181 aagtggcatc ttatgccttg cagttagtgt cagcaacaag aagccatgct gccatccagc
     3241 ttggcatcag tccacgagga agcctttcct ttattcaggc agcaaaagct tatgctttaa
     3301 tccatgggag aaattacgtc acgcccaaag atttgcagga tttagttcct tacgtgtttt
     3361 cccatcgcct gattttttac gatcgttcat tgaaggaaga cgaaaaaaaa caaatcattc
     3421 atactcttgt tgcacaaatt cctgttcctg tgaggtagat tgaggtagat aatggaaaaa
     3481 atcaaagatt atttcattaa ttttgtgtta tttctggtat atttcatcat tgtgcttttt
     3541 gctcttgtat tcaacaattc tttaggctgg ttcttgttgg ccttttttac tctttatgta
     3601 tcatggagct tgatttcatt aagcagcttt ctaaagaaac tttcggttac ttgtacattg
     3661 cagccactcg tttatcgcaa aaaaagtatg caggttattt tttccatagc aaaaaagaga
     3721 actttttctt tacctctccc tcgtttacaa atcggcttcc cagcaatctt tgcagaaaaa
     3781 aaacaagaga ttttgattct tacaaataaa ccgcaagaag tccaattgct ttggcagcca
     3841 aaagaaagag gatgccatga aacattaact gtcattttta cagcctatga tagtctagga
     3901 cttttcagaa aaagtgcaaa aagagagatc tcttttcctg tgactgttct gcctgctttt
     3961 tgtaagattc aagcagaaaa attacagaga gttctggaaa aaaaacagca gctgaacgcg
     4021 taccaaagag gtcttgattt tcgggaacat cgcgcttatc gtccaggtga ttctttcaac
     4081 cgaatcgatt ggaaattgtc tgctcatact caagagtggt tataccgtga atacgattat
     4141 caagaagaag aatgttctcc tcttttttgc ttttggggtt cgcacagtcc aaaatttgaa
     4201 cctctgctag acttgtattt ttctttatgg catttgagaa aagaaaagca gccggaactt
     4261 ctgatattag gcaaccgcgc ctttcatggc aaagaccccg gtcataccta ttttgcttct
     4321 ttggaagctg gcgatgagaa agcttttttc gcacacctaa aaaaatatgc aaaaaaacaa
     4381 atcgtcctct ttgttcctga gaattctcct gaagtctcag aagctattga aacattgtca
     4441 aaagatcgaa cggtttatct tgtttatttc gtagaaaaac aactcatggt ccaagaaaaa
     4501 gacaagatat gttcattgcc aggaggtgaa tggattgacg attaaatggg aaaaatggct
     4561 gtgtggcgtt tactcctttg tgatactaag tgtaggtgct ccgatatttg tagtagctaa
     4621 tcaattgcaa aacagctacc ttcttatcct aactattggt gtcctatgcc ttattgtctg
     4681 ctgtattcct aaaaaatggg tacgtttgct gctttctttg ccagtaatga taggttgttt
     4741 gtttttgtat tttccttcga agacattttc cttattatgg atcttacagt ttttttcgtc
     4801 agtcacagag gaattcttcc atctatccca aggtaaactt tattatttgc cagaaaagac
     4861 agcttttttt ctcataatgt tgctgatcta tttatttatt acattgaccg tggattacga
     4921 ctatttgtac gcaccctttc tttctttgat ggcttacttc atgatgctta ccgtttttcg
     4981 ggaaaaagat ttactgtacg aaatgattgc ggtagtaact gttttgttcg tgtatctggc
     5041 agcaaggcaa tttttctcca tgcggttgtt gtcgggaaac actcgattcc agtcattgac
     5101 tacagttctg cttatttgtt tcttaactat tagcgctatc ttgcctttat atcttccgaa
     5161 agtacaccaa tctctcgagg aaacgagtga accgatccga gaatatctta atgatgaagg
     5221 gctttatgat acactccatg agtatcaatt aaccggaagt gcaagaacag gcttcagtga
     5281 gaatgatgaa cagcttggtg gacctttata tgataatggc gaagttgttt ttacagcgaa
     5341 ccaaaaagga aatggctatt ggaagatcga aaataaaaat cattacaccg gttctggatg
     5401 gatagaagat caggacgcac ccatccaacc aatccaagaa ttccctgttg acatcacgag
     5461 ctaccaaacc gttatggaag acaaagaaaa cattacattg accctaaaaa aacaagcttt
     5521 cttaccttat ccttatggaa atactacctt gactgatttt tcattagcta gtggacaaac
     5581 gctttactat ttgcctgaaa gccagcgatt cattcctgtc ccgaatgaat cgacacgttc
     5641 tgcaacttta caaacagaaa ggttagtttt tacgagagaa gaattaaaaa gcagtcagtt
     5701 aaaagctgat gatttagaaa atcagcagac aaatcttcaa ttgccaaaaa gtttgcctaa
     5761 acgtattgag gacttggcgg tcgaattgac caaaaatgaa gcaactttaa ttcgtaaagt
     5821 cgaagctgtc gaacagtatt taaaaacaag cggaaatttc cgctattcca aaacggatac
     5881 cggacatact ccgaaagaac acgattatgt ggattatttc ctctttgatt caaaagtcgg
     5941 ctattgtgac aacttttcaa cttctatggt cgtccttctt cgaacacttg gtatcccagc
     6001 tcgctggaca aaaggtttta caaatgggct cagaacaggc acagataatc aagggaatga
     6061 ggaatacagc attctcaata gtcatgctca ttcttggcca gaggtatact ttcctggatt
     6121 tggctggctt ccatttgaac caaccccttc atttgccaat ccaatgggtt cacaaccagt
     6181 tgctgaaaca accgaaaccg tccagcctgc tatcgaacaa ccaaatgaaa gcgaaaatat
     6241 ggcagaaact atttccagtg agagatctga ggtcattcca tcagaagaaa caacactcac
     6301 accagcttat aaaatcgtct tattcagcct tggggtgtgt ttatacgtct tgttgttctt
     6361 tctattgtta ttcagaaaat ctctgcgctg gacaagttat cttatctatc ttcatttttt
     6421 tgcttctact aatacgattg catatcaaaa acttcttaac catttggaaa cattggtacc
     6481 gcgcaaaccc gcagaatctt tgcaggaata tagcctgcga atagaacaag aattcaagct
     6541 agatctgcgt ttcattcgat taactactca atatgaagca gaaatatatg gacgacaagc
     6601 agatccggta aatttcgata aaaaaaccta tttagaaatt acgcatataa taagaaaaac
     6661 ggtatacaaa aaagttctga caaaagggag ccgcttcaaa aaataagata aaatttctgg
     6721 agaatctact tctggaatgc cgagaaccag ctgcttgagt atcgattatt cgaaaaaaag
     6781 gttgtgacac gttttttgtc acaacctttt ttcattatta tttgattttc aatgtcaaag
     6841 catttagagc tacaactacc gtacttaacg acatcaagac agcaccaact gctggactta
     6901 atatgatacc aattggcgca agaattccgg ctgctagcgg aattgcaaga atattgtaac
     6961 ctgcccccca ccagaggttc tggatcattt tctttcgcgt ttgcttggct agatcaagaa
     7021 aatgcaaaat atcttttgga tcgctgtttg tcaatacgac atccgcagaa tcgattgcga
     7081 tatctgtccc tgcaccgatt gccatcccga ttgaagcacg ggctaaactt ggcgcatcat
     7141 tgatcccatc acccaccatg attacttttt tcccttggtc aaggtatttc tggacaacag
     7201 cttctttatc atctggtaat aaaccgccat aatattcttc gatccctaaa taatctgcta
     7261 ctgcttgggc agcgttttta ttgtcaccag taagcatgac aggagtgatt tttctttctt
     7321 tcaatgttcg gataaattct tttgcttctg tttttactac gtcacctaaa gcaacgattg
     7381 cagctagatg attttctaaa atcaggaagc tgatggtatt tccttgttct tggtaaggtt
     7441 tcaataatgc ttgttctacg tttaatccga gacgctcaac ttctttttca ttaactattt
     7501 tcacttgttg gtttttgact gttgcctcta gcccaactcc tgaaagattt tttagatttt
     7561 cggcttgata aggcttgatt tcatgttctt tcaaataatt cataatacca acagccaatg
     7621 gatgattggc attcgcttcc aatgctccta aatattgaag gatttcattt ttattgaacg
     7681 catcatcaag tacttcgaca cccgttacag taaattttcc ttctgttagt gttcctgttt
     7741 tgtccagcat gatcacatct agatcattgg cttgctccag tgcattgcgg tttttcaaaa
     7801 gtaatccgtt tttagctgct attgatgtag agcgagcaac aactaatggg atagctaaac
     7861 ctagagcatg aggacaggcg atgataaaga ctgttaccat acgttctaat gcattaggaa
     7921 gatctgtcaa gaacaaccag gcgatgaatg ccaggatacc cacaattaat gcgacataaa
     7981 acagccattt tgccactttg tcagataatg actctagctt ggatttttct ccttgtgctt
     8041 ttcgcaccat ttccataacc ttcgctagat aaccattttc accagttcca gttacttcga
     8101 tttcgatcgt tccatcccca ttgatagaac cgccaatcac tttgtcattg gcttgttttt
     8161 tgattcctct tgattcgcca gtcacagctg attcgtcaac aattgtttca cctttcaaga
     8221 ttacaccatc tgttggcatt ttatcaccag accggacgat caaacgatca ccttcgttta
     8281 cttctttcaa tgaaactgtc tcttcttttc catctttcgt caagcgtttt actgattctg
     8341 gcagtaattc tgctagtttt tgtaaagcat tgctggcatt cgacacagca ttcatttcaa
     8401 tccagtgacc tagtagcata ataacgatca aagtagccaa ttcccagaag aaatccatga
     8461 cgtgtgtatg tggattgagc agatttgcga taaacgaata gacactataa atatatgcaa
     8521 ctgtaatccc catcgcgatc agtgtcatca tagcaggact tttttgtttc aattccatct
     8581 tagctccact taaaaatggc tgaccgccat agataaatag tatagttgct aagatcaata
     8641 cgagccaatc agaaccagga aacgttactt gaaatggaaa ttccattccc atcattggtg
     8701 aaaaaagaat gattgggata gctaggataa gcgatagcca aaatttttgt ttgaaatttc
     8761 ccatgtgcat ggaatgatcc atgccgccat gatcgtgatc catgtgcatc gaatggtcca
     8821 tttgtttgct gtttgctata tctccatggt tatgtcccat gtgcatggaa tggtccatct
     8881 ggctatggtc atgtttcatc tccatctgtt tttcatgaga ttctgtactt tctttgttta
     8941 ctacttcttt tttatgttca tgtcccatgt gcatggaatg gtccatctgg ctatggtcat
     9001 gtttcatctc catctgtttt tcatgagatt ctgtactttc tttgtttact acttcttttt
     9061 tatgttcatg ttttttctcc atatcgttcc cattcatttt tactccatcc cttctcttac
     9121 tttttcatgt gccgatttaa gctcagggag ttcaacaata cactgacgga actaaacgcc
     9181 atcgctcctc ctgcaatgat tggattcaaa aagcctagtg cggcaaaagg aataccaatc
     9241 gtattataga caaaagccca gaaaagattt tgtttgattt ttctcaatgt caccctagac
     9301 aactcgattg tttgtgcaat ggatgccaaa ctgctactca tcagcgtcac atcggctgtt
     9361 tccatcgcga tatccgttcc acttcccatt gccataccaa catcagctaa tgctaaagcc
     9421 ggtgcatcat tgattccatc gcctgccata ccgacttttt tgccatcttt ctgaagtttt
     9481 tctacgtagg ctgctttatc ctctggaagt acttcagcaa agatatgctt tggatcaata
     9541 ccaacttgtt taccaatcgt ttcggctgcc agtttgttgt ctcctgtcag cataaaaaca
     9601 tctaatcctt tattctggag ctgcttgatt gcttgtttgg cttctagttt gatttgatca
     9661 gccacggcaa tcaacccgat cacttgcttt tcatcagcta aaaacatgac tgtttttccc
     9721 tgctgttcta attctaacgc gtgttcttgg tattcatcaa atgataggtt caattcaatt
     9781 aatcgtttac gtgtacccgc aaaatagcgt actccgttaa tcgtaccgct gattccagca
     9841 cctgggtgag ctgtaaaatc aatcatatcg tatgttgctg cttcttgcag ttttccgtat
     9901 tccacgattg ctttacctag tggatgttca gaagcttgtt ctaaagtata aaaaatagat
     9961 aggacttctt tagaaccgac tagatctgta actttgggct ttccttctgt aatcgtccca
    10021 gttttatcca aaacaatgct gtctaagtga gcagctgctt ctaatgcttc tccgccttta
    10081 attaaaattc catttcgtgc accaacaccc gttcctacca taatagctgt tggagtcgct
    10141 aaacctaatg cacatggaca cgcaatgact aatacagaga cactatggat caatgcgagt
    10201 tgccaatcac cagtgatcaa acctgtagct atgagcgtga taaacgcgat gactaatacg
    10261 atcggaacaa aaatccctga gatccgatct gcgatttttt ggattggggc tttgctccct
    10321 tgagcatctt ccaccatttg aatgatttgc gctaatactg tctgcttgcc gacttgtgtg
    10381 acttccatgt gtagcagacc attcgtattg attgtcccgc caaaaagcgt gtcatccgga
    10441 ttcttttcta caggaagatt ttcaccagta agcatacttt catctatcgc actgcttcct
    10501 gaaataattc gaccatctgc tggaatctgc tcaccaggac ggatgactag ttgatcacca
    10561 acgactactt cttcaatcgc taacgtttct tctttcccgt ttcttatcac ttgggcggtt
    10621 tttgtttgaa gagacatcaa ttgtttgatt gcattacctg ttttcgtttt tgctgtatgt
    10681 tccaaatatt tgccgagcaa aatcagcgtg atgatcatac tgctgctttc aaaataaaga
    10741 tcttgggggt gtccacggaa aaatccgttg taaatgctca atgcaaaggc agccgatgtt
    10801 ccaattgcta ccaatacatc catatttggt gctttcgact tgattgcatg gtacgcacct
    10861 ttataaaaac gagcaccgac ataaaattgg acaggagcag acagcactaa ctggacgatt
    10921 ggaaaatgaa aaaagtgaac aatcgccgca tggcttccta acatcatagc aatcattgac
    10981 aacatcaacg gcaaagtcaa aaccgtactc aatataagat cgaatagcat ttttttcaaa
    11041 tacgcttgct tttcttctgc aattttttgt ttgtgggctt catcgtacaa aattgcacca
    11101 tagccgatgt tttctacgct ttggattaat ttttcagtgg tcgtcccttc atatttgaca
    11161 cttgcttttt cagtggccaa gttgactgtg gcattgacca caccaggttg tccgttcagc
    11221 tctttttcga tcctagcaga acaatttgca caagtcatac ctgtaatgac gaacgtatcc
    11281 attttggttt ctgctgttgc catcaaatca cctctgcttt ataacccaat ccattgattg
    11341 cttgacaaat cttttcggat tgaacttttg tttcatcaaa cttgaccgta ccgtttgctt
    11401 ttttcaaatt tactttcact ttttgcacgc cgtcaagtgc gcttactgtt tcttctactc
    11461 ttgctgcaca atgattgcag ctcatacctt cgattgaaaa ttgttgtttc attttttctt
    11521 cctcctattg atgttgttta cattcacatt gacctgggat acagttacat tcgatcgtat
    11581 ctactggttg cttttgttcc agttgtttca aaatctcatt gatatcttct tgagtcaaag
    11641 tggcttcttc tactagatcc gcaatcgtct ctccaatcct ttttgcacag atatgggaaa
    11701 aaagattttc cgtcgcactg cgaactgttt ccatctccga gacagctgga tgataaatga
    11761 atttttttcc ttcttgttct gtccagatca cttctttttt taccaaacga cccagcaaag
    11821 ttttgatcgt tgctggtttc caatccatcg aatcagctaa gatctgcgtg atttcttggg
    11881 ctgtcgtctg tccaagtgtc caaataacac gcatgatctc ccactctgaa tcactaatct
    11941 ttactggcgt tttgactttt tccatttatt tcacaccttt cgtttacaaa tgtaatcatt
    12001 aacttatgaa tacagattac acttgtaaac aaaaactgtc aattattttt gctctctatt
    12061 ttcaatttag ttaaaaattc ttgtttctct cgtcttgttt taaggatgat cagtttattt
    12121 cttgcattag ctacttggat cagctgctgt atttttggtt cattgtttcc ttcaaaatgc
    12181 cagataaaag ataaaaattc taagtatttc ctgtttagtt tctccgaaaa tgattcaggc
    12241 atatctggcc gagatttttt gtttatcttt ctttttagag aacgccaaac tactcggtag
    12301 atggcgagat aacgcggcac tttaagccaa atgatcttat ctgcttcttt aatcctttcc
    12361 tctaacgtag aagtataatt tccttcaacg atccatgacg gattagatac cataaacgat
    12421 tgctgttctt gcaaaaacca cttttttgcc tgaatgcgga aagccggtga tttctttgat
    12481 cttccttgcg agggacgatt ttcccgaccc actttgtcca atcacgatga tcttcattct
    12541 tctccctcac ttctctttgg aatttggttc gatcatacca cttataacgc cgcaaaaaaa
    12601 caagggactg tgacaaaagt cgtgtcaaag tcccttgttt cgaataaatg gtgttcaatc
    12661 agctgacctt cagcattagc tcaaaaaacg gcaaaatatg aggagctatt tttgtttggc
    12721 tgttcttatt acttgatgca ggacagcttt ttcacaacct ctgattcacg gtgttccaga
    12781 agtagcttct gtcacaacct cttgtaacaa gtatttctat tttaaggctg aaccactgtt
    12841 tctggttcag taatttcttt gtttttgtct cgacgagcaa ttgctggcaa gatcatacct
    12901 aataagatca agacaattgg tgtgatgata ttcgtgaata attggaacca ccatgcttta
    12961 ggatcagcag tataatctac ttttggcacc attcctagga tacatgcaaa cgcagtgaag
    13021 gcaaagcacc aagcaccaaa gataaaaccg atttttggat ttttaacaaa tttatattca
    13081 gaattgaatt tcttataagc tttattcaac atcatatatg ccaagaacac ccataggtaa
    13141 cgcattggca tgacaactga gttcaagttc gtcaaccatt ttactaattc attcatatct
    13201 ttgataccaa agatcggcaa caaaataatg attcctacta gtatacctgt cagaagataa
    13261 ccattcacca atgtaccttt acgattacgt ttacgtagcc agtttggtac aaattctgga
    13321 tccgcatctg ctaacaagat ttttagtggt gcatcaattg aaaaggctaa tgcggagatt
    13381 tgtccaatca tgtttgtcaa tgcgtaaatg atcatcaatg agttaccgat accatagtaa
    13441 ttacctaaaa tttgaaaagc actgtatgcc ccatttgcca tcaagtcttt agggatatta
    13501 tcgctagcaa acagcatacc cattgcgact gagcctaata cagcacaaat ccctaccatt
    13561 gctgctaaga agatcatccc tttaggaaat tcctttgcag gatttcttgt agagttgaca
    13621 taaggggata ttttttccgc ccctccaact gcaaatacta gcatcgaaac ggttgtgaaa
    13681 taactgaaat caaatgttgg aatatatgtt ttcacttgat tcatatgtgg tgtggcaaat
    13741 tccatcgttg gattgatgaa cggtgccgtt acagctaaaa gaataaataa gatcgacatg
    13801 acgaacatcg ctgttccggc cagtccgcca atcactttca aagtagaaag tccttttgtt
    13861 gataaatata aaaaggcaag aaatataata agtgaaataa ctgctaccat ttgtactgac
    13921 atcgtattta cgatatttcc atttccttgg actgcccaac caccagcaat cagaattgct
    13981 tgaggctttt gtgccaaata aggaatatgg acgacccagt aagtccaagc ggcatagtat
    14041 gccagtcgtt tattagatgt cgtattttcg acccatgaac tgacgcctcc tttactatcc
    14101 ttgaaggctg atcctaattg tccaacgatc aatgcgtatg gaataaaata aatggccaaa
    14161 atcaatagcc aagaggtgac aactgatact ccttgctgag catagttatt aactacattc
    14221 cccatgcccc aaaccatgtt aaatgcaatt aacgcaacag taaaccagcg taattgtttg
    14281 ttgttcattc gttctctcct ttatgataaa aatttgttat ccagatgtaa tcatattcaa
    14341 tttttaacaa acttacaaga cagtgttatt ttatgtgtgt attcttttat ttaatacaca
    14401 tcgttttttc atattttttc catcaaaaaa ataagttatt ttcttttatt tcattgacct
    14461 tattgaattt caagctattt tgaattttct gcaaaattaa aaacattagt tattttataa
    14521 tcctatctat tttctttaca tttttcatta agaaaaggat ataaaaaaaa gaggacgttc
    14581 attcgtcctc ttcattgatc aacgtttatt ttttacatgc aagcttcgca tggcattcaa
    14641 aacagctaat actgtcaccc caacatctgc aaatactgca tctcccattg atgcaaaacc
    14701 aaaagcacct aaggaaagta ccaaaatttt tatcccaata gcaaagacaa tgttctgttt
    14761 gacgattttc aatgttttct ttgctaaatg gattgcttct gcaatcttcg atggttgatc
    14821 attcatgatg actacatctg ctgcttcaat tgcagcatcg cttcccaatc cacccattgc
    14881 gattcctaca tctgctcttg ctagcaccgg tgcatcgttg attccatctc cgacaaatgc
    14941 ggtcttttta ttgttacttt gtaagatttc ctctaaccgc tgcactttat cttctggaag
    15001 caattcgcta tatatcttgt ccacgcctac ttgcttcccg atatgatcag caattttttt
    15061 cgagtcgccc gtcaacatga ctgtgttttt cacaccagcc tgttttaatt gaaccaatgc
    15121 gtctacggca tcttctttca aggtatctgc aataacaaga taaccactgt aactttgatc
    15181 gatcgctaga taaagcaatg taccgatttc ttgacttgaa ggaaaagaga tttcaaatct
    15241 ttccatcaat ttgtgattac ctactaatac ttgtttgcca tcaacttcag ctaagatccc
    15301 ttcacctgca aattcctgga tattagctgt tggtaaaagc ggacctgcgt agccttctaa
    15361 aacagattga gcaatcggat gtgtagaaaa ctgttctgca cttgcaacat attgcataaa
    15421 tttctttgga tcaattcctg ttggatcgat cgtctggatc gaaaagtcac ctttcgttaa
    15481 tgtgccagtt ttatcgaata ccactgtctc agtttgtgca agcaactcca agtaatttga
    15541 accttttact aatacaccga ttttacttgc tcctccgata ccgccaaaga aactaagtgg
    15601 cacggaaatc actaatgcac atggacatga gatcactaaa aatgtcaatg ctcgatagat
    15661 ccattcagaa aacgccgctc tagaaacaac aagtggaggt aaaacagcta ataaaacggc
    15721 caatcctaca acgactggtg tgtaatagcg cgcgaattta gtaatgaaat tttcagctgg
    15781 tgctttttta ctgctggcat tttctactaa ttctaataat ttgctgatag tagaattttc
    15841 ataagatttt tctacttgaa ctaaaaatgg tttattttta ttgataaatc cgcttaatac
    15901 tgtttcacca acatatacag atttagggac tgattctcct gtaagtgctg acgtatcgac
    15961 taatgattct ccttcgatga tcgttccatc taacggtaca cgttcaccag gcttcacaag
    16021 tacaaactga ccgatcagca cgtcttcagg gttcacggtc atcaatcctt ccgccgtctg
    16081 cacgtgagct gtttctggac ggatcgccat caattcgcga atcgattttc ttgaatgact
    16141 gactgccaat ccttggaaat actcgccgat ttgataaaat agcatcactg ctacggcttc
    16201 tggatattca ccgatcaaca tagcgccaat cgtagcaaca gacataagaa aattctcatc
    16261 aaagattttt cctttgacga tattcatcac tgccttcttc actacatcat atcctatcag
    16321 cagataaatc aataaatacc ctatcaagcg aattggttca ttaaaatcaa ataatagcaa
    16381 taaagcgata cctgcaaggg aaaataaaat ccggaacagc gtatttctct ttttttcatt
    16441 tccatgttca gatacttttt ccttatctat ttctgttact ttgacatctg gttctaattc
    16501 cttcactact ttttttgttt cttgttcaat cgtagccaaa tgatcttcct ctgcgtcaat
    16561 cgttagtttt ccagaagtga agtttaccgt tgcttccttg actccattga ttttctgaac
    16621 tcctttttcg attttcattg cacagttcgc acaatctaaa ccttctaatc tgtaactttt
    16681 cattttaatg acctcctcgc ctcaacatat gaatatctct tcataactaa ttataaatga
    16741 atggttattc atatgtcaag gtatccgaaa gaaaaaatga aaaacatctg catcggaaaa
    16801 tttcttccat acagatgttt tggcttattc tttctttttc tcttcgatca ttgccactgc
    16861 tcttatccaa cccgcacttg ccttcttgat cttgacagga tagcaactaa gtttgaagcc
    16921 tgttgctggc aatttgtcta aattcattaa tttttcgata ggacaatatc ttttttcaat
    16981 ccctgcaaaa tgtccttccc agatatacga agctccacta cgctttcaaa aatatagaaa
    17041 gagttcttta atgaaaatta tttcaacttt ccataaacag taaccccata taaataaaag
    17101 acgtaaaagt cacatagaag aacttataca ggaaaacgca tagagtcagg tgaaatacat
    17161 gtatcccacc tggctctatg ctttatctaa cctttattat tctcttttat acaatttctg
    17221 caccgaatgg catcaacgcc aatcgagcaa gtttgaaaga ttgcttggca aaaggtatcc
    17281 ctatgatcgt gatacataga aggatgccgc tgacgacatg tgcgagagca attggtaggc
    17341 ctgaaacgat cagccagatg atattaacga tcaatgacat gccagactgg tgataaatta
    17401 cttctttgcc aaaaggcgca aaagaaaggg aggcgatctt aaaacattgc ataccgattg
    17461 ggatacctat gatcgtgata caccaaagta tccccgctgc taaccagcta agaccaccga
    17521 ttagtccgcc gaatataaac cagatgacat ttcctaaaca actcattgta tttctccttc
    17581 tattactgtt tttgattaaa actgggcaaa aattgatttt attcttcttt ttttagcttc
    17641 cagcatcaag tattctgcaa attttttttg gatttcttcc gtattttctt ttgttactaa
    17701 tgtgtgttgg attagttttc ctgatggtcg ctgatccaat cgttcttctg actgttgcac
    17761 gtccgcttgc gcaaatccga taatccgttt ttcttttgtt acagcaacga gcaatagttt
    17821 attcttatca tttaggtcag ctgccgtttt tgcttttacg aatgattctg gatgatcagt
    17881 aatcagctga ttgatttgag gtaaatcttc ttttactgcc caccttattt ccatcatttt
    17941 tcacttttct ttcgctcatt tttatctcca ctaaaaaaat cgactgcgac aattgcatct
    18001 atccagcttt gtgcaatgat ctcatgtccg ccaatcgttg ggtggacccc atcttctctt
    18061 gtatatttcg aaaaaccata agcaatccct aaagcattga atataccatc taaaggaacc
    18121 agcaatgcgc catattcctt agcaagttta cgaacaattt ggattttagg gtctaagtct
    18181 ttacgccagc catgacggtc gtcggttata ggaagtacaa acggctccat caagatgatg
    18241 ttgcagattt ccgctgtttg aagttcattt agtaattttc gataaacgga ttcaaattgc
    18301 tgagcagatt tctcagttcc gaatatagcc tgatcgctag tattatgcca ggtatcattg
    18361 attccgatca aaatcgatac atagtcaggt tgtaaagcta aacaatcttc ttgccagcgt
    18421 acttgcagat ctgcaatttt gtctcctcct atcccacggt tcatgcattc aaattccatc
    18481 gttggatatt gggagattag ttttccggca atcaaaagtg gataaccttt acctagatca
    18541 gttgcttctg ctcggtatct tcctgcgtct gtaatgctat caccgataaa taatatacgt
    18601 tttttcattt gtcaaaaact cctttttgaa taaaacgatg attttcttcc ttatattatc
    18661 ccataagccc tatcaagacg aaagagaaaa tatatgtata aaaaatgaca ccagcctagt
    18721 tccttcaaac aattgaatga acgctcatca agtgtctagt tttttatgct atttttttct
    18781 taacgtgccg gattcccctt gattccttcg ttgtttggtc cagagagatc gatcacaccc
    18841 aagcttccgt caatcagacc actgatgacg ccatcgaaac atatatttat aggctcatct
    18901 aagacttcta gtaaatgtcc ctttactaat atctcttcta gattgcttgg gatagattgg
    18961 tcataacttt atctggtccg atgatttcaa gggtgaattg aacttacata tggattattg
    19021 catgctgaaa atacggacct actccatctt cgaatgttac tattagtttg ttttcaggtg
    19081 ctagatgctg ctttatttca acagcagaag catcatcaaa tcagatttcc atttgaatta
    19141 ccttctttgt aaatgtttga ttgattgcga tttcgttata gaaccttgtg aatcaaatag
    19201 caatttcttt tgctttcttc tcttgtctgc tggaaacttc cattatcccg tatttaaaaa
    19261 aaagaactgc gagagttcgc agttcttttt tttaaataaa cgttgctctc cggccacaag
    19321 tcacaatagt catcaaacat gaaaaactgt tttttgaaat tactccttgt gactcggagc
    19381 tgaacggcag gcgcacaacc tcttatggat aaattcggtt caacaaacgt gggaatggaa
    19441 tagcttcacg tacatggtcg ataccagcaa tccaagtgac tgttcgttca agacctagac
    19501 caaaaccaga gtgcggaaca gaaccgtatt tacgtagatc aagataccat gaatattctt
    19561 tttcatccaa accgtgatta cggatttgtt ctagcaagaa atcatagtcc gttgcccgtt
    19621 cgcttccgcc aataatttca ccgtaacctt ctggtgcgat catatctgca caaattacca
    19681 cgtcttctct tgttggatgt ggtttcatgt agaatggctt gatggctttt ggatagttta
    19741 ggataaagac aggctgttcg aatgaattcg caatgaacgt ttcatgaggt gaaccaaagt
    19801 cttcgcccca ttcgatgtca tcaaatccat ttttcttcag taattcgatt gcatcatcgt
    19861 aagtaatacg agggaatggc aattttgtat aagtttttaa gacttctttg tctcgtccta
    19921 gtacatctaa tgcgtattcg caatgatcta aaacattttg tactaagaat gctacatatt
    19981 gttcctgtac ttctaaactt tcttcttgat gagtgaaagc catttctggt tcgatcatcc
    20041 agaattcgat caaatgacgt cgtgtttttg atttttcagc acggaaagtc ggaccgaatg
    20101 aaaagacttt tccgaaagcc atagcagcag cttccatgta taattggcca ctttgagata
    20161 aataagcttt ttgatcaaag taatttgttt cgaatagatc cgtagtgcct tctggtgcag
    20221 aaccagtcaa gatcggcgga tcaattttga caaaatgatg ttgattaaag aattcatacg
    20281 ttgcacgaat gatttcattt ctgatctgca taatcgcatg ttgtcttgaa gaacgcagcc
    20341 ataaatgacg atgatccatc aagaagtctg ttccgtgttc ttttggtgtg atcggataat
    20401 cgtggctctc gcttaccact tccacatttg taattccgat ttcataacca aattttgaac
    20461 gactgtcttc acggatttct ccagttacta acacggatgt ttcttggtgt agatttttag
    20521 ctgtttggaa aacttcttcc gacacttcgc tttttacaac tacaccttgg aaaaaggctg
    20581 ttccgtctct taattgtaaa aatgtgattt ttccgcttga tcgcttattt gcgacccaag
    20641 cgccgattgt tactgtttct cccacatggt ttttcgaatc gatgatttga atttgttcca
    20701 cgtatgactc tccttttata ttccttgaat ttcttcagga ttaattttga cttttactct
    20761 caataaattg cttgattctg cgtaccgctt cttctaacgt agcgcgatca gtagcataac
    20821 tcatgcggac attttctggt gccccaaagc cttcgccagt cacaagcgct acccctgttt
    20881 cttctaaaag atcttctacc cattgtgtga cattttcata tttacacatg cgtagcgttt
    20941 cttttacatt aggaaaaaga tagaaagctc cttgcggctt ttcaagagaa acacctggca
    21001 gttctgccac aagcggatat aacgtattca ggcgttcttc aaaggcgttc cgcatttctt
    21061 ctactgtatc ttgctcacct ttcaatgctt caacagctgc atattgactg actgctgtcg
    21121 gattactggt tgactgggaa gcaacagcaa tcattccatt gatgatctca gaattcccca
    21181 ccgcataacc aatgcgccag cctgtcatcg catatgtttt agacacgcca ttgatgatga
    21241 tggtctgatt tttgattgct tctgaaatcg ttgcaattgg agtaaactca ttgccattat
    21301 aaactaaacg accataaata tcatcagcaa ctatcaaaat atcatttttt actgcccatt
    21361 caccgattgc ctgaagttca ttcttgctat aaatcattcc agtcggattc gatggagaat
    21421 tgatgattac ggcttttgtt ttttctgaac gtgcttgttc tagctgttca acagtaactt
    21481 tccagctatt ggattcttcc cctttcacaa agacaggaag tccttctgcc agttttactt
    21541 gctcaccgta actgacccag taaggcacag gaatgatgac ttcatcttgc gggtcaagga
    21601 tcgtttggaa aagggtatac aaagcaaatt tcgctccgtc tgttacgact gtttgtgaag
    21661 gttcatagac aagtccatag tttttcttca gataatcaac gattgcctgt cgaagctctg
    21721 ggattcctgc tgttggtgta taatagctag ctttcccatt gcggattgct tcgattgctg
    21781 cttcttggat gttttctggt gtcgcaaaat ccggttctcc cacagtcaaa ctcagcacat
    21841 ctctgccttt tgcttttaat gccttggcct ttgccgcagc tgccaaagtg acagacggtt
    21901 ctaatcgttt tgttcttttt gataactcca tcccattcat tcctttacct tttaaattcc
    21961 cttgattgtc ttgacttcat ctccagattc aaagccaatc aggtaataat tcagtttccc
    22021 atttgtttct tttcctacta cttcccacac aggctgatca tcatacatcc ctaaagcagc
    22081 tttttcgatt tggatttcag gatgggccgc agcaattgtc tgttttgctt cgttttcagt
    22141 cagtcccttt gtttgatcca atacttttac tttttcacca gatttaggaa tgataacggc
    22201 gatttctttt cctttatcat ttgtacctgt cagtgaaaag tatgtcttct ttcgagtaaa
    22261 ccaataaaaa tgatcggctt cctcaagatt tgcatatttc tttgcgattt ctactgcttc
    22321 tttcttcgcc tgcaccgccg gacgactgga acgcaagtaa aaaatcgagc tgatcacgat
    22381 gaccgctaat aaaaatacga tcaagccaag taacacgcga ttaatcgttt tttcctttgt
    22441 ctgttttttc ttcaagggtc gtcgctcctt tatcttcatt ccttttcatt atagcagatt
    22501 ttaattatga aaaaagacag ctcctctaac ttccttcttc atttttcttt aagaattcat
    22561 ggatgtcctg atagatttcc tccatagcta gctctttgat cggtactttt ttcggtaatg
    22621 catggatgat ccgtgcacca tattttgcag tgactagtct tcgatccaaa ataagcaata
    22681 cgccacgatc tgtctccgtc cttatcaagc gacctaatgc ttggcgtaac ttcaaagctg
    22741 ctttaggtac ggattcctgg taaaaaggat tgatcccctc tgattctaaa taagcgttcc
    22801 tagctttgac catcgggcga agcggattat cgaagggtaa acgtgtgact acaacgatct
    22861 gcaaagcatc cccaggcaaa tctacacctt cccaaaagct gtcagcgcca aacaatacgc
    22921 ttttttctga caaaatgaag cgtttcaaaa gcttctcccg gcttccgcca aacccttgag
    22981 ctagtatttc tcgtcctttt tctagcatag acagatgcat tttctgatag accttctgca
    23041 aaacatcatg agaagtgaat aacacaagta ttggccgatc ttcttgttcg atcagacctg
    23101 taagtgctgt ctctaaataa tcgatatatg cttgattgct gacttgatgg acggcaggtg
    23161 cctcttttgg cacatagatc cttgcctgtt tctcataatc ataaggagag gcaatcactt
    23221 taagaggtgc tgcttcaatg ccaagccgct tagagagata gtgtcgatta gggccgatct
    23281 tcagcgttcc tccaatataa agaatacgat catatcgagg ataccaaaca gtcgacggca
    23341 acatagccgc ttgaaaatca tggagatgaa aaatcatctg ctgcgctgtg ttcccaggaa
    23401 cgaaccaatg gatcaaatga tctcgccagt cttccagcca ttgatccatc agcaagtact
    23461 gcttgtctaa ttgatcaaat aagctatata aacttgctaa atcgatccgc atctggtttg
    23521 tccagctttc ttggataatc tcaaaagtca gacgcatttg tgactgtagc tgctggatct
    23581 cctgataaaa aagctgcagg tgatcaatgg ctgtcccaga ttccagtggc agctgatcca
    23641 acatctcttt tgtcatcatg acttcttctg gatactgtcc gttaggttgc ttgccgctca
    23701 ctaaactcat taatccttct gccatacaaa tctgtgcttc gcatagcgca gaaagttctt
    23761 ctcgataaat cgataaccag cgtaaggctt catgttcttt cggtaaatag ctttgtattc
    23821 ggtcaaacag ctgatttggt tcttctaatt gctggatttg tttatggaaa tagttaatac
    23881 ttaatcgttt gtcatttact ttttcagcga tttccggcaa atgatgtact tcatcgatca
    23941 acaaaaatgg actagctgga agcaatggtt cttttcgctg tgtttcttgt attaaaaacg
    24001 catgattgac aatcaaaaaa ttactttgcc tgattttctt ttgcaagaaa cgaacaaagt
    24061 cttgttcgta aaatgactga tttcttgcta aaaatccaat acctctgtgc gcgatatctg
    24121 caaagaatga atggttcaaa tttgttaaat gtaattcatc caaatcaccg gtcttcgttt
    24181 gcgtcagcca aactaagacc gccatttgat acaaagcata ttgtttttgt tctggcggtt
    24241 ccacaagtgt gcctttaaaa cgctgtaaat caatatagtg gcgatagctt ttgataatta
    24301 caggttgtat gggctgatct agcaattgat tcagcaatgg aatgtctttt tctatgatct
    24361 gctgctgcaa aactagcgaa acggtactga tgacagcggg tttttcaggt gtagccaaat
    24421 aactcaatgg cagcagataa ccgattgttt tacccattcc tgtagctgct tcgatcatca
    24481 aatcttttga ttcatctttt gtgaaatggt cgtagaccgc attcatcagt ctgttctgtt
    24541 cttttcgata catcagtgtt ttaccaaaca ttttttcttt tgcttgtttt tttcttggat
    24601 atgtccgctc gccataatgg acggatgtga atagttccac ttcttttttc tgcaaagcta
    24661 gcccatcgac gatttctaat gagggatcaa gtggctctgg tttttctttc atttcttcaa
    24721 tcacatgata aatgaaacga ctcgtatcca tacctgtgtg tctacttaat cgcgcaatct
    24781 gctctaacgt gatgattggc aattttctca tccgttcttc gatcagcaaa agaagttgac
    24841 ccgtcacttc ggcatcacta tctgcctgat gaggattctc atgaataaat ccaaggcttt
    24901 ctgacaaatc agctaagcga aagcttggtt ccgtcggcaa gaaaatttgt gcaagttcta
    24961 ctgtatcgat gcctggtatc ttcaaactag gaagtccgca tcgcatgagt tcatggttca
    25021 aaaaattata atcaaaataa atattatgcg cgacaaatat ggtgtctgcc aaaagattgt
    25081 aaatcgtttg ggcgacatct tcgaaataag gcgctttttg gacgcgttga ttcgtgatcc
    25141 ctgttaaatg ctggatttgt tttgaaatct tccgccctgg atgaatatcg atcgaaaaac
    25201 gtgaagtgat ccgacctgat tcaatcatga cgcagccaaa ttggatgatc cgatcttctt
    25261 ttggattcgt cccagtcgtt tcgatatcaa cgactgcata agttcttggt ttcaaaatat
    25321 cttcctcttc tcctgcctct aatgttcttt tgaaattata ctacaaagtg cagaaaaata
    25381 ctctcatcgc tttttaaaga aaatagacaa aaacgcccag acacgcaaat gtctgggcgt
    25441 ttatttttta gtataggtta attaagcttt agtaacgttt gttgcttgag gtccgcgttg
    25501 gccttcttca acatcgaaag ttactgcttg gccttcttct aaagttttga atccgtcgcc
    25561 ttggatagct gagaaatgaa cgaatacatc gtttccgttt tctgcagtga tgaatccaaa
    25621 tcctttttct gagttaaacc attttactgt acctgtttcc ataataaaaa tcctccttgt
    25681 gtatcaacac atattttgca attacttgaa tggtgtatat ctggaagatg tttatttgaa
    25741 acaagctacc acagattacc gaacaaaaac tactcctata gtatatcata ccgtttacaa
    25801 aaaagctaga gtttttcgac tttttttatt aaaaaaagtt ttctcagcga ttacataaag
    25861 tgaaaaaccg aacttttttt aaaataaacg acatattgtt cagttggtgt ttttttgctc
    25921 tgatgttctt ctttaaacta aaaaaattat tctttctgac tacttatcgg ttctgtttca
    25981 acggtcgagg ctggggaaga ttctttagta ggtctgatgt tctcatggta tttctgatag
    26041 cctatgacag ttaccagaag aacaaggcaa accaatacga tcaacgagat tagtttttct
    26101 tttttgctca tatctatacc tcataaataa caggatgatg tccatcatat ttctgagtat
    26161 gagtaaaagc aaaagctgca gctgtagaat gtaagaaatg ccagcaactt tcataatcac
    26221 aggtcggaca gtaccaaaag taaccaaatc ttggctgcaa agaccgttct tctgtttcag
    26281 gaatcgcaga atcaagatct gttgtctgta cataaacatt tttgtacaga cgtgtgcctg
    26341 taataggaga ccgctgtgtt tcttcagcaa aaactggctg acttgttaaa cttagggata
    26401 gaaacagcaa acaccataac agtctttttt tcataaagac ctccttatcg ataagttttt
    26461 cccaattaaa atcatatctc aagaacgccc gttattcaca ttttgttcat aaatgatgtt
    26521 ttttgtatca taatcgtcaa aaagaggtcg tgaccacgtc acaacctctt tttt
//
LOCUS       DAPBAF010000042        25500 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.042, whole genome shotgun sequence.
ACCESSION   DAPBAF010000042 DAPBAF010000000
VERSION     DAPBAF010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 25500)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25500)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25500
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.042"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            131..3658
                     /locus_tag="RD451_002074"
     CDS             131..3658
                     /locus_tag="RD451_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HDT7567309.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3655..7377
                     /gene="addA"
                     /locus_tag="RD451_002075"
     CDS             3655..7377
                     /gene="addA"
                     /locus_tag="RD451_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HDT7567310.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7446..7787
                     /locus_tag="RD451_002076"
     CDS             7446..7787
                     /locus_tag="RD451_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7567311.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8096..9139
                     /gene="pheS"
                     /locus_tag="RD451_002077"
     CDS             8096..9139
                     /gene="pheS"
                     /locus_tag="RD451_002077"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HDT7567312.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIVRKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9144..11564
                     /locus_tag="RD451_002078"
     CDS             9144..11564
                     /locus_tag="RD451_002078"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HDT7567313.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11734..12744)
                     /gene="trpS"
                     /locus_tag="RD451_002079"
     CDS             complement(11734..12744)
                     /gene="trpS"
                     /locus_tag="RD451_002079"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HDT7567314.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            12998..13735
                     /locus_tag="RD451_002080"
     CDS             12998..13735
                     /locus_tag="RD451_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HDT7567315.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            13749..14564
                     /locus_tag="RD451_002081"
     CDS             13749..14564
                     /locus_tag="RD451_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HDT7567316.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            14577..15224
                     /locus_tag="RD451_002082"
     CDS             14577..15224
                     /locus_tag="RD451_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HDT7567317.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            15240..15896
                     /locus_tag="RD451_002083"
     CDS             15240..15896
                     /locus_tag="RD451_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HDT7567318.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            16058..16879
                     /gene="racE"
                     /locus_tag="RD451_002084"
     CDS             16058..16879
                     /gene="racE"
                     /locus_tag="RD451_002084"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HDT7567319.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            16882..18237
                     /gene="rph"
                     /locus_tag="RD451_002085"
     CDS             16882..18237
                     /gene="rph"
                     /locus_tag="RD451_002085"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HDT7567320.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            18238..18756
                     /locus_tag="RD451_002086"
     CDS             18238..18756
                     /locus_tag="RD451_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDT7567321.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            18863..19363
                     /locus_tag="RD451_002087"
     CDS             18863..19363
                     /locus_tag="RD451_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HDT7567322.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(19643..20563)
                     /locus_tag="RD451_002088"
     CDS             complement(19643..20563)
                     /locus_tag="RD451_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HDT7567323.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            20728..21741
                     /locus_tag="RD451_002089"
     CDS             20728..21741
                     /locus_tag="RD451_002089"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HDT7567324.1"
                     /translation="MQIDWNNLGFSYIKTPWRFIAKWKDGQWEEGELTEDNYLTIHEG
                     SPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLMPMVPEKMFVDAVK
                     QVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVFCTPVGAYFKGGLK
                     PTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCVYLDPATHTKIEEV
                     GAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIEGDIFIDDLDQFAE
                     AGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGIQFGDIEAPEGWIE
                     VVE"
     gene            complement(21851..22606)
                     /gene="fabI"
                     /locus_tag="RD451_002090"
     CDS             complement(21851..22606)
                     /gene="fabI"
                     /locus_tag="RD451_002090"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HDT7567325.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            22826..23266
                     /gene="fabZ"
                     /locus_tag="RD451_002091"
     CDS             22826..23266
                     /gene="fabZ"
                     /locus_tag="RD451_002091"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HDT7567326.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            complement(23381..24142)
                     /locus_tag="RD451_002092"
     CDS             complement(23381..24142)
                     /locus_tag="RD451_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDT7567327.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            24331..25425
                     /locus_tag="RD451_002093"
     CDS             24331..25425
                     /locus_tag="RD451_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HDT7567328.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
BASE COUNT         8447 a         4425 c         5384 g         7244 t
ORIGIN      
        1 tttgcgtata cttaaaaaag tagaaatatc agaaccttaa aaggatataa tttgaagaat
       61 atagaacaaa tgttcagtat tttttgatat aataaaggag caccgtatca tgtgttgaag
      121 gaggaaaagc atgtctttac aatttattct tggaaacggg aaaaaagatc accgtcaagt
      181 cttgatcgac gaagcatccg cttggctcga ccaggatgca agtaaccaag tatttttcct
      241 tgttcccaac tacagcaaat tcgaacagga acaagaaatt ttagcggaga tgcgaagaag
      301 aagcggaaaa aaaactttca gcacaacaaa cgttcaagta tttagttttt atcgtctggc
      361 ttggtatttg ctgcaacaga caactcttct tacaggaaat gaattatcag aatcaggatc
      421 tgcaatgatc ttgcgacaga ttttagaaaa aaatgaggaa gaattaacaa tctttcgcgg
      481 agaaatcaat aaaagagggt ttattcgtca attacaagaa ctctacagtg aattgcgtac
      541 aggaaatatt caaccagaag acctgatgct tttatttggt gattcaccta atgcagaaga
      601 ccagcaactt aaaatgaaag acttgaagct gattttttca gcttatgaca gcgaattgac
      661 tcaacgtgca ctaacaaatg aagatgcact atctatacta gcaaattata tgcagacaca
      721 agatttcaac aacgtcaaat ttattgtcag tggtttttct cgaatcaatg gtcaagagta
      781 tcaattactg caggcaatga tggaaaaggg gcaattggtt gtcgatttat tgctggatcg
      841 tccttataca gcggatcttc cagaagtact tacgctcttt catgagactg gaaagcttta
      901 tttccgtctt tttcaaagtg caagagaacg gaaagtccct atattagtgg accgatttgc
      961 accagagcag actcgtccga cagagcttca actgctgcaa acaatgtggg aagagacatc
     1021 tagccaaaag aaagcggcag tacacaaaat agggggacaa gagcatctcc atttgtggga
     1081 agctgaaaat ccaactgaag aagtccgaca attagctgtt gaaatcagac gactagtcag
     1141 tgaagaaaac taccgttatc gtgatatcca agtgctgaca aaaaatatgt ctttatatgg
     1201 aaatatcctt cggccgatct ttcaagaaat ggcaattcct ttttatatcg atgaagaaca
     1261 aatgatggaa aatcatccgc tgatcgaatg gatcaacagt ctgttcgctc ttgaccgcta
     1321 ttcttatcgg ctaagtgata ttatgcgttt tttcaaaact gaattatttc tgtcgacgga
     1381 agcagaaacc gaacttgatg aatggaaaca agagcgagat gaattcagga aaaaactgga
     1441 catcactgaa aatgtagcac ttgcttacaa ttatcaagga acttattgga ctcgtgaaaa
     1501 agactggcag tttgtggcgt atgattttga agcagaacag attgaagacg tacagtattt
     1561 ggaagaacag tcaaatacga ttagacgatt atttcagaaa gctgtaccag tatttttgaa
     1621 aaaaataaag aaaagcaaaa caggacaaga ggccgcaaat gttttttatc aatttttgat
     1681 ccaaagtggc gtacagcaac aattattgtt ttggcgtaat caggaagtag acagaggaaa
     1741 cttagaagcg gcaagaaacc atgagcagac atggggagcg ctgattgatc tgttggatga
     1801 atatgtagta atttatggtg aatcggcttt tgactggtca ctgttccaag aaatcattac
     1861 aagtggtcta gaaaatctaa gttatggtaa aatccctacc gcaatcgacc aagtgcgaat
     1921 caatcgtttg gaattagttc gaccaaatca agctgccgtc acttttgcat tagggttgaa
     1981 tgatcaagtg tttccagacc gaaaagagac aaaaggattg ttgtccagtg aagaacgaga
     2041 agtattaaat caggccttgc cagatggaca gtttttattc gacccatcaa aggaaagtat
     2101 ctcttttgag cctttccaag cctatcttgt ttttctttcc ggaacagatc gattatatct
     2161 tagttatgca caaagctatg acacagatgg ttcgctgaag atgtctcctt atttgcgtag
     2221 aatcacagaa tatttatctg ttcccgtcga gagaaaagag catttgacga tcgaaagcga
     2281 ccctaattgt tatgtaggga cttacagaag cggaatcaat acagtcaata ggatttatcg
     2341 attagcttta gatgaaaaaa aacctgtacc aaagcactgg caaaagctca aagaattagt
     2401 actgaattcg tcatggcgaa attttgcttt acagattttt gaaagtcagg aacatttaaa
     2461 tgttcctgtt tcgatgccag aaaaaatggc ggaagagctt tatggaaaag agatttatac
     2521 ttcaatttca cgtatggaga atttttataa ttgtgaatac aaatacttca tgcaatttgg
     2581 tttgaaattg aaagaacgaa ctgtttatgg tctaactcca gcagcaactg gtgattttta
     2641 tcatgaatca ttggatcgtt tcttcaagct actgttttca aaccaattat ccttagtgaa
     2701 tatgtccgat gcgcagcgta gagactttac tgaaaaagtg ctgcaggaag tattcggaga
     2761 acttcggttt gagatattgg atagttctgc aagaatgaac tatatccgct accagttagg
     2821 acagacgatt caaaaagtga catgggcttt gcaaaaacag agcaaaaata caggcatgca
     2881 tcctcttcag acagagattc tatttggtca gattgctgga gcaaaaggta tcacaggtct
     2941 ggaattaccg ttgagtaatg gtggaaaact ccatgttcga gggaaaatcg atcgaatcga
     3001 tgtagcttct gaacaagaag atacttggct aagcgtcgtt gattacaaat ctagcggacg
     3061 ttcattcgat gtcacagaag cttattatgg catggctatg caattattga cgtatctgga
     3121 cgtagcattg atggatgcgg tacgtttgac tggaaaggcg gctgttaaac cagcaggatc
     3181 atattattta catgttcata atcctgtatt gacggagaca gatgatgtag agaagaatac
     3241 attgaaaaaa tttagttatg atggcgtttt tgtcgatgat cccgctcttt tagaagtact
     3301 agatcattca ctggaagcaa aagaacaatc actgatctat ccagtgaaaa aaaatgcgaa
     3361 agatgaatac caaaaaggta gtttcagtaa agacaaattt ttcacggaag aagaactgca
     3421 actattcatg gcgcataatc gggaaaatat gcggttagct ggagatgcga ttacttccgg
     3481 agaaatcaaa ctaaatccag cttataaaga taaacagcgg attgcctgcg aattttgtcc
     3541 attcagaagc atctgtacgt ttgatgtgat gctgaaagaa aataattacc accgtctgga
     3601 gaaaatagat aaggaagaag cactgcgtag aatattgaaa aggagtgaag aagagtgaat
     3661 caaattcctt taaaaccgca aaatgaacga ttcacagatg atcagtggca agcgattttt
     3721 gatcaaggag ataatctatt agtctctgcg tctgccggat caggtaaaac tacagtgctt
     3781 gttcgaagag tgattgaaaa actaaaaatg ggttttgata tcgatgaatt attgattgtg
     3841 acatttactg aagctgccgc aagagaaatg aaagaaagaa ttcaagaggc attacaagaa
     3901 tccgtcaata gcgaaagtga ccctgtacgt agacagcatt ttactaagca gttagtttta
     3961 ttgcccacag cgaatatctc aaccttacat gctttttgcc tgacagttat tcgacgttat
     4021 tattacttaa ttgatattga tccagtcttt cgcatgttaa cagatgaaac agaaacgatc
     4081 ttgatgaagg aggatgtgtg ggacgagctg agagaagcac tttatgcaga aaatgatgaa
     4141 cgatttttcc aattaacaat gaatttttct aatgatcgtt cagatgacgg cttgacgaat
     4201 ctggtgtttt ctctttatga gtttgcccgt gccaaccctg acccccaaaa atggctagaa
     4261 cagttaagcg ataattatcg tttgcctgag gggctagcga aatctcgatt atatcaaaaa
     4321 caaatccgtc ctttagtttt ggcagatata taccaatgtg tacagttata tgaacagatg
     4381 actcagttag cacaaggtga aggattagaa aaaatgcatg agcaagtagc tggagaacaa
     4441 cagcagatca agaatatcta tgaagcgttc tcgcaagatc ggttagaaga agcttatgct
     4501 ggtttggaac aactaacttt ttcaactttt aagagcagtc ggaaagcaga attgaaagaa
     4561 atttccaatg aagtcaaggg catgagggat aaagcaaaaa aactgattca gcagataagt
     4621 aaaagttatt ttcctgtttc cccaagccaa atggaagaat taacggacaa agcactaccg
     4681 ttagtcgaag aaatgacaaa agtcacgcaa agcttcatgg acggtttcag tatgcgtaaa
     4741 cgggaaaaag gtgtgctgga tttcaatgat ctggaacatt tagcgttgca gattctcaca
     4801 gaaaaaacga aagatgtatg gctgccaagt gaagcttcaa aacattatcg aaaaaaattc
     4861 aaagaagtaa tggtagatga atatcaagac gtgaaccaat tacaagaagc cattttatac
     4921 tggctaagag aacccgatga tacaaaagga aatatgttca tggttgggga tgtcaaacaa
     4981 tccatctatt ctttccgttt agcagatcct agtttattta tcgggaaata cgagaatttc
     5041 tcaaagaaag aaggcggacg tcgaatcgtt ttggctgaga acttccgctc tagaaaagaa
     5101 gtcctttctt ttacgaatct tatttttgaa caactaatgg atccagcagt gggtcaaatc
     5161 aattatgacg aagcagccaa actgatccaa ggattttcag actttccaga gaatgaacag
     5221 tttgagccgg aaatcatgat ctatgaaaaa gaacaggaag aatcagagat tgagattccg
     5281 acggatgata tactggaaga caaaacagaa ggcgaacttt ttatgacagg actaaaaatt
     5341 cgtcaattaa ttgattcctc ctttatgatt tatgataaaa aatcaaaaaa aagtcgtccg
     5401 atagagtaca aagacattgt tctcttgaca cctacaaaga agaacaactt aacgatttta
     5461 gagattttca aaacattgga tattccatta gagatgaatg atgctcaaaa ctattttcaa
     5521 gcgacagaaa ttcgcacgat gatctcgctg ctacaattaa tcgataatcc ctatcaagat
     5581 attccgcttg cggctgtatt gcgctcaccg atcgtgggtc tgattgaacc agaattagcc
     5641 agcattcgat tagctaaccg tgcacatact tactatgatg ctgtgcttgc ttatcaagca
     5701 tcaaacgaag atgaattagc agctaagctg gaacattttg gcaagcaact agagcattgg
     5761 cgagaacttg ctcgccgttc ttcgatcact gacttgttat gggatatcta ttatgagacg
     5821 ggatatctag agtatgtggt cggtctgcca gcaggggcac agagacaagc caatctttat
     5881 gcattggttg atcgtgccaa agcttacgag caaagttctt tcagaggatt ataccagttc
     5941 gtgcgtttca ttgaaaaaat gcaagaaaaa gataaagact tagcagaacc agtcatttca
     6001 atagaagata atgctgttcg cgttatgacg atccatgcaa gtaaaggctt ggaattccca
     6061 gttgtatttt tgttagatat gacaaaggag ttcaacttac aagacttgcg caatcggtat
     6121 gcttttgaag aaaaacttgg agcaggaatt cgctatatgg atcctgaaac acgagtgtta
     6181 tatgatacgt taccgtttca agccatcaaa ttggcaaagc aaaacaaatt gttgtcggaa
     6241 gaaatgcgta aattgtatgt aggattgact cgggcagaac aaaagctttt cattgtcggt
     6301 tcctataaaa ataaagagca aatgatccaa acgtggtctg aagcagctga tcatgaggag
     6361 ttagtttttg atcctgcgct acgtttgaag ggcagaagca gcttgatgaa ttggattggt
     6421 tacggattga tccgtcatcc tgaaatgcag aaatacttag aggaagaaat ttcgacttct
     6481 cttcttcaac attcaaatgc acagttttct atttcatgga tgaatcagca atcgatcatt
     6541 gaacaaagac agttgcttgc tgaaaaagaa ctggttaact tagatcagca gatgaaagaa
     6601 gatgaaactt tattagcaga ttcgttacaa aaacgtctgg catatgaata tccttatcaa
     6661 gcttcttcac aaaccacaag ttatcaatct gtatctgaaa tcaaacgatt attcgaagat
     6721 ccagatgata cacaagaatc acgtttgact ctggaaagca gtcagaacaa agcagcatcc
     6781 cgtcaatttc gttatacgca agaacaacta gcagaaccaa aatttttgca aaaagatcgg
     6841 caagtgtcag cagctgctgt tggaactgct acgcatgctt tgttacaatt actgccatta
     6901 gagatgccaa ctacagagag tatccatcaa aaattacagg aattggtaag gaaacggtta
     6961 gtagacgaaa aagtcgcgaa aaaagtagat gtttcttcta ttatatggtt ctttcaaaca
     7021 gaacttggtc aacagctgat tgccaacaaa gaaaacgtaa aacgagaaca acctttttcc
     7081 atgctgcttc ctgctgacga agtatttcaa gactatccaa atcaagaaga tgaactatta
     7141 atccacggaa tcgtcgatgg atacctagaa gaaaaagatc atctcaatat ctatgatttt
     7201 aaaacagatt ttattttaca tccggatgat ccagcagaaa tagatgcaat cgtccaaaaa
     7261 tatcaaggac agctaagact ttaccaacaa gcaatgtcag aagctttgaa taagccagta
     7321 gaaaatgttt tcctaatttt gcttcgagtg aaacaaatta taaacattaa caaataatta
     7381 taattgagca aacttgactt atgttttgta aggattatgc tatactctgg gaagaggtga
     7441 gtatgatgga gctaacacag acagaattcg ttttatgccc taaatttgaa aaaacattct
     7501 ctattttagg aaaaaaatgg aacggattga ttatcgatgt actactcgaa aacggtccgc
     7561 aacgctttgt tgagcttgcg gcaaaaatcc cgatggtcag tgatcgagta ttagtcgaac
     7621 gcttgaagga attagaaaaa gaaggaatag tcactcgaaa ctttgcctgt agcgaaaaga
     7681 gccgttcaga atatctcttg actgaaaaag gagcagactt gcaaaaagcg atgcgtcaaa
     7741 tacaagtttg gagcgaaaaa tggatcacag aggaagaatg cggttgattt tgtaaaaaaa
     7801 atcttgtaaa ctatagtcca tacgaataag taaagaacga tgacgaaaaa gagtagtttg
     7861 gctaaaccag ttcagggaga tctgtcgcag actgaaagca gatcctgtgt ttgaaaaatg
     7921 aagttcactt tccgagttcg tctgataaaa tcagaccggc aattgtcgtt aacgaagtaa
     7981 gagtgcggtg taagtcattt atccgcaaat taggatggta acgcgaagac ctcgttcctt
     8041 aacaggaatg aggtcttttt gttttgtatt tggaatttaa aggaggaaca agcacatgtc
     8101 tctacaagca caattagaga gcttgaaaga agcaacgctc gtcaaaatca cagcggcaca
     8161 agatttaaat gaattaaatc aaatacgtgt tgaaacgtta ggaaaaaaag gaccgatcac
     8221 agaagtatta cgtgggatga aagatctaag tccagaagag cgaccaaaag tcggaagttt
     8281 cgcaaatgag atccgagatc ttttgacaga agagatcgtg cgaaaaaaac aagtattaga
     8341 agaagaagcg ttaaatgcag ctttggcaaa agaaacaata gacgtgacac tacctggtag
     8401 aaaagtaaaa catggtacac gtcatatcgt gacacaaatc atggaagaaa ttgaagatat
     8461 ttttgtgggt atgggctatc agatcgtaga aggatatgaa gtagaatctg atcattacaa
     8521 tttcgaacgg atgaatctgc caaaagatca tccagcaagg gacatgcaag atactttcta
     8581 tatttcagac gagatattga ttcggacaca tacttcacca gtccaagcac ggacaatgga
     8641 aaaacatgat ttctctaagg gtgctctacg aatgatctcg ccagggaaag tcttccgcag
     8701 agatacagat gatgcgaccc acagtcatca gttccatcaa attgaagggc tagttgttga
     8761 taaaaacatc acaatgggcg accttaaagg aacattagaa gtcgtaatga aaaaaatgtt
     8821 tggggaagat cgtgaaattc gtttgcgtcc aagttatttc ccatttacgg aaccatcagt
     8881 agaagtagat gtcagctgtt tcaaatgtgg tggtgccggt tgtaacgtat gtaaatacac
     8941 tggatggatc gaaattttag gagctggcat ggtacacccg aatgtgttga agatgtcagg
     9001 aatcgatcca gaagaatatt caggctttgc tttcggcctt ggaccagacc gcgtagctat
     9061 gttgcggtat ggagtgaatg atatccgtaa tttctatcaa aatgacttac gtttcttaag
     9121 tcagttcaag ggggagtaag aaaatgttag tttcatataa atggctcaat cgttatgtag
     9181 atttatcgaa tgtaacacca aaagaattag cggataagat gtctgtgaca ggaatcgaag
     9241 tagagggagt aacggttcca gaagaaggct tgaaaaaaat cgttgtcggt gaagtcaagg
     9301 aatgcgtacc acatccagat tctgatcacc tttctatttg tcaagtcgat attggcgaag
     9361 acgaactgtc tcaaatcgtt tgtggagcgc ctaatgtgaa ggttggaatc aaagtgattg
     9421 ttgcacttcc taactcacgt atcgctggta atgtaaaaat caaaaaagga aaaatgcgtg
     9481 gccaagtatc aaatggcatg atttgctcat tacaagaaat tggctattca gatagtgtta
     9541 taccgaaaga atacgctgaa ggtatctatt atatgccaca agaagctgta aatggcgatc
     9601 cagtttttcc ttatttggat atggatgatt cgattattga attatctatc acaccgaatc
     9661 gtgcggatgc attgtcaatg cgtggcgtag cttatgaagt tggggcaatt tatcgtcaga
     9721 ctcctacatt cgatgacgaa aagctggtag aatcctcacg tcctgctagc gataaaattc
     9781 aagtggaagt tgaagataaa gaagcagttc ctgcttatca aatcagaatc attgaaggag
     9841 taagaatcca gccaagtcct caatggctgc aaaatctttt gatgaacgaa ggcattcgtc
     9901 caatcaacaa tgtagtagat gtgacgaact atattttgct tttattcgga caaccactac
     9961 atgcatttga ctacgacaaa ttgaaatcaa aagagatctt tgtccgccgt gcaaaagaaa
    10021 atgaaacatt agtaacacta gatggagaat ctcgggaatt gacaactgac aatctcgtca
    10081 ttactaacgg caaagaacca gttgctttag ctggtgtcat gggagggtta gactcagaga
    10141 tcacgaatga aacaacaaca gttgcactag aatctgcttt atttgatcca atttcgattc
    10201 gtcgtacagc aaaacaattt aatttgcgta gtgaatcctc tgcacgtttt gaaaaaggaa
    10261 tcaaccatgc gactgttgga gaagccagtg aggttgctgc agcaatgatc gtttctcttg
    10321 cgggtgggga agttctacaa ggcgcggtca aaggctcaga gatcaaagca gaagacgtat
    10381 cagtgaagat ttcacttgaa cgcatcaatc aatatttagg aacatctctt gtcgttaaag
    10441 aagtaaatga gatttttgaa gcacttggat ttagctatga agaaaaggag tatgtttatt
    10501 ccgtagtagt accaccaaga cgctgggata tccaaatcga agcagatatt atcgaagaag
    10561 ttgctcgtat ttatggatac gaccagttgc catctacact tccaagtgga gaaacggttg
    10621 ctggaagctt gtcaaaagaa caagaaacta ctcgtaaaat tcgtacaatc tttgaaggaa
    10681 gcggattgag cgaagcaatc agttatgcat tgacaacaga agaaaaatca agacagtttg
    10741 ttataaatga aagtaatatt acacgtttgg actggccaat gagcgaagaa cgttctgtat
    10801 tacgaatgaa tttgatcagc ggactattag atgatatcag ttataacact gcccgaaaaa
    10861 atacagagat tgctttatat gaaattggtc gggtgttctt ccaagaaaat gatccacgta
    10921 cacatctgcc gcaagaagta aaacatgcag caatcgctat ttctggtatt tgggaagaaa
    10981 aagattggca gacgaaagct caaaatgtag actttttcac catcaagggt cttttagaaa
    11041 acttatttga acaactaggc atcactgaag atgtccatta tcaaacagtg acagaaatga
    11101 aggaaatgca tcctggaaga actgctgcga tttaccttgg cgaaaaattt attggttttg
    11161 tcggtcaagt gcatccaacg attacaaaaa gttatgatat tccagaaaca tatgttgctg
    11221 agtttgattt atctgctata gtggaagctg ctcaaaaagg gatcgttttc gaagcagtga
    11281 caaaattccc agcagtcagc cgggacatcg ctttgcttgt aaaagaaact gtgacaaatc
    11341 aggaattaac agaagttatc cgttctgctg ccggaagatt tttaacagat atccaattat
    11401 ttgatgtcta tcaaggagaa aacattgaaa aaggacataa atccatggcg tatagcctga
    11461 cattcgtcaa cccagaagca acattgacag atgaagaaat caataaagca atggaaaaag
    11521 tcgaaaaagc gttggtagaa aacctagagg caagtattcg ctaagaagga aaatatagta
    11581 agtaacgatc aagtagcttt tgaagaccat acatttgaaa aaaagatgtg acacaacttc
    11641 gtcacatctc tttttttgat tttaaaaaag gaatagcaca gagacgagat aaaaaaacag
    11701 gcctttacag cctgcttttt tagagtaaat gaattaatgg aagtaattga ttcccattgc
    11761 tgattttact tcagaaagtg tttgtgcagc tactttagca gcttcttcac tacctttacg
    11821 taagatttcc ataacagctg aaggatcttt ttccaattct tctcggcgcg cacggatcgg
    11881 tgcaaattca gcttccaata catcaatgag gtatcgtttg atctttacat caccaagtcc
    11941 gccgcggcgg taatgagctt tcatttcttc aattgcttct ttatctgttc cgaatacatc
    12001 caagtaggtg aagaccatat tcccttctac ttgtccagga tcttgtacat ggatgtggtt
    12061 tggatcagta tacatactca tgactttttt ctgtaagaca tcggcaggat cggagatata
    12121 aataccgttt cctaacgatt tactcatttt gccatttcca tcgattccag gtaatctacc
    12181 cattcctttt ggtgggaata cgccttttgg ttccaccaag acttcaccat atgtatgatt
    12241 gaagctttgt acgatttcct gtgtctgctc tagcattggt ttttgatcct caccaacagg
    12301 tacaagattc gctttgaatg cagtgatatc tgctgcttga gaaacaggat agataaagaa
    12361 tcctgtaggc acgctttcac cgaatttttt ttgttcgatt tctgttttga cagtcggatt
    12421 gcgccgaacg cgtcctacgc tgactaagtt caaataatac atggttaatt cagctaattc
    12481 cggaatttgt gattggataa ataaagtaga ttttgcagga tctaatccca cggctaaata
    12541 gtctaaagca acttgcaaga catttgatga aaccttctca ggatttttag cattatctgt
    12601 cagtgcttgc atgtcagcaa tcatgacaaa cagttggttg tcttcatctg cctgcatagc
    12661 cactcgggtt tttagagaac cgacgtaatg ccctaaatgc agcttcccag ttggtcgatc
    12721 tcccgttaaa ataatatttt tcaaaaaaga cacctcttta cgatttgtaa gtctgagcac
    12781 ttaatatctt accgtttttc ctgaaaagaa acaacagttc ctaaggaaaa aacaaggaaa
    12841 gaggataaaa taactaatag attagaaatg gaagaaatat ttatgggaga ataaacgttc
    12901 taagaaactt tacaaattac taaactatca gatataatgt attttattat acatctttaa
    12961 aagaaatctt actaaataat aatgggagtg taattctatg gcaatgatta aatttgatca
    13021 cgtggataaa tattatggca agttccacgc attaaaaaat atcaatctcg aattcgagaa
    13081 aggagaagtt gtcgttgtca ttggtccttc tggttcagga aagagcacga tgcttcgctg
    13141 tatcaatgga ttagagacga tctcttcagg taagctgctg attaatgata ctgacttgca
    13201 tgataaaaag acaaaactga cagaagtccg aaaaaacatc ggcatggttt tccaacattt
    13261 caatttgtac ccaaataaaa ctgttctgga aaacatcaaa ttagcaccaa tcaaagtgtt
    13321 gaagcaagac caggcaactg cagtcaaaaa cgcggagaaa tttttgaaaa ctgtcaatat
    13381 gttagataag aaagattctt atccttccat gttatccggg ggacaacagc aacgggtggc
    13441 aatcgccaga ggtttagcga tgaatcctga gatgctgctg tttgatgaac ctacttctgc
    13501 tttggatccg gaaatgattg gtgatgtatt agacgttatg aaaaaattgg ctcatgacgg
    13561 tatgtcaatg attgtcgtga cacatgaaat gggctttgcc aaagaagtgg cggatcgtgt
    13621 tatcttcatg gctgatggag aagtattgga agacagcaga aatgtgagag actttttcga
    13681 aaatccaaat gaagtccgag cacagcaatt tatcagtaaa gttatcaatc attgatagga
    13741 ggaaaaagat gcgcaggtta aaaaaaatac gcctgatttt ccttttaggc attgcttttc
    13801 ttgcactagc cggatgtaaa ggaaatgggt tggcaaatga agatatttta gagcgaagca
    13861 aatctaccaa tgaaatcatc tggggtgtca agtatgatac tcgattattt ggaatgatgg
    13921 atattgagag cagaactgta caaggatttg atgtagatat tgcaaaagca atcactaaaa
    13981 agatccttgg tgacaatgga aaaacagaat ttgttgaagt cacttctaaa actcggattc
    14041 cattattgaa aaacggaaat atcgatgcaa ttattgcaac gatgacgatc acagatgaac
    14101 gaaaaaaaca ggttgacttt tcagatgtct atttcgatgc tggccaagct ttgttggtaa
    14161 agaaaggaag ccaaatcaaa agtgtagatg atttgaatgc ttctacaacg gttctagcag
    14221 tcaaaggttc tacatcggct gcgaatatcc gacagcatgc accagatgca aaaattttag
    14281 aattagaaaa ctatgcagaa gcatttactg ctttacaatc tggtcaggga gacgcgatga
    14341 ctacggataa tgcgattttg ttagggattg cagatgaaaa tccagagtat gagttagttg
    14401 gtggaacgtt tactaatgag ccttacggga ttgcgatcaa caaagggcaa gaaaacttct
    14461 tgaaagctgt taaccaagcg ctagaggaaa tgcatgcaga tggcacatac gataaaatct
    14521 atcaaaaatg gtttccaaat gaaactgaag gaaaagtaga gtaaggggga gaggcaatga
    14581 gcgaattgat acaaacttat ggaccaatct ttgtcgacgg gttcaagatc acattgtttt
    14641 cgagtgtctt agcacttgtg tttagtttga ttatcggaac gttaatggca atcttccaat
    14701 tatcaaagaa taaagtagtg agcgccttag caaaggcata tgtagaattt tttagaaaca
    14761 ttccattatt aatcatcgtg atgttttttt atgttgtcgt accgatttat tggtttaatc
    14821 tagatggatt ccaagcaggt acgattggat taacgatcta tacatctgct tttattgctg
    14881 aaacagtacg ttcagggatt caaaccgtac caaaaggtca aacagaagca ggactatctt
    14941 ctggttttac ctattcagaa atcatgcgtt atattgtttt accgcaagca ttcaaaatcg
    15001 ttatcccgcc attaggcaac caatttatca acctcgtaaa aaactcatct attttagcaa
    15061 tcgtagctgg tttagatttg atgtatcaag gagacttgat cgctagtgaa acattcaata
    15121 ccttcgatac gtatatcatc gttgggttat tttacttagt tatcacgcta ccgttatctt
    15181 acttaatggt ttatcttgag aaaaaatggg cggttcgttc atagaaggag gggaaataca
    15241 tggattttag cggcgctttt tcatggatga atatccgttt tttattggaa ggattaaagg
    15301 ttactgttga agtttcattg ttttcgatca tttttagttt cttgatcggt ggtctgacag
    15361 gtgtgattcg ttttgcgaat atccctttct tttccaaaat ccttggtgta gtgattgata
    15421 ttatacggaa tcttccatta ttattgatca ttttcttcac ttactttgcc ttacctcaaa
    15481 tcggcattca gatgaacatc ttctggtccg ctgtcgcagc attaacgatt tttgagtcag
    15541 ctatgttgtc ggaaattttc cgagctggac tcaatgctgt tccaaaagga cagatggaag
    15601 caggattatc aacgggactg acttatgtag aatcgatgcg aacgatcgtg ttaccgcaag
    15661 catttaaatc aatgatcccg gcaattgtga gccaattgat ttcactgatc aaagatactt
    15721 cattagcagt aatcatttct ttacctgaac tttctcatca ggcacgtatt atttatggac
    15781 agaacaccaa ttatgtgctt ccgatgttca tcatcatgac acttatgtac ttcgtggtat
    15841 gttacgcgct ttctctgctt tccggttact tggaaaagag acggtacagt tattaataga
    15901 tgattctttt agcggttgtg gcaaactaaa gtcacaaccg cttttcctct ttccattcga
    15961 aaaaaagaga tttcgattgt tttaagcaag taagagcact tgaaaattca cgctaaaaag
    16021 tacacaatag ggaggataga atttattgaa aaaaaggatg atacgattga cagataatcg
    16081 ccctatcgga tttattgatt caggtgtcgg cggcttgact gtagtaaaag aagccctgaa
    16141 acaattaccg aatgaaaata ttttatttgt aggagacaca gcacgctgcc catatggccc
    16201 tagacccgcg gaacaggtaa tccagtatac ttgggaaatg acggattatc tggtggagca
    16261 aggaatcaag atgctggtga tcgcctgcaa taccgcaact gcggtggctt tagaagaaat
    16321 caaagctgct ctttctattc cagtcatcgg tgtgatcctt cccggtacta gagcggcagt
    16381 aaaaaaaaca caaaataaac aagttggcat tatcggtacg attggtacgg taaaaagtca
    16441 agcttatgaa aaagcactga aagagaaagt accagaattg actgtgacaa gtcttgcttg
    16501 tcccaaattt gtttcagttg tcgaaagtaa tgaataccat tcatcggtgg cgaaaaaaat
    16561 tgtggcagaa acattagctc ctttaaccac taaaaaaatc gatacattga ttttgggatg
    16621 cacccattat ccattattac gccccatcat tcaaaatgta atgggagaaa atgttcaact
    16681 gatcgattct ggagcagaaa cagtaggtga agtatctatg ctgttagatt atttcaattt
    16741 gagcaattca ccgcaaaatg gtcggacatt atgccagttt tatacaactg gctctgccaa
    16801 acttttcgag gaaatagctg aagactggct tggaatcgga cacttaaatg tagaacatat
    16861 cgaattggga ggaaaataag gatgcgtcat gacgggagaa aagcccaaga gcttcgcaaa
    16921 ctggagcttc aaacaaatgt tttcaaatat ccagaaggat cggtagtgat ccgttttggt
    16981 gatacaacag ttatttgttc tgcaacaata gaaaattctg ttcccccttt tttgagagaa
    17041 acaggaacag gatgggtgac agcagaatat agtatgctgc ctcgagcaac gagtacgaga
    17101 aatcgtagag aaagcagcaa agggaaactt tctggtagaa caatggaaat ccagcgtctt
    17161 attggtcgtt ccttgcgtgc agtagtagac ttggaaaaat taggagaacg tagtatcatc
    17221 gtagactgcg atgtgatcca agcggatggc ggtactagaa cagcaagtat cactggggca
    17281 tttgtggcat tgaaattagc cattgaaaaa cttttaagag aaaaagaatt gtcagaagat
    17341 ccaataaaag aacatcttgc tgcagttagc gtaggaatct taccagatgg gacttgcgtc
    17401 acagatttgg attaccaaga agattccgca gcacttgtag acatgaatct tgtaatgaca
    17461 gaatctggaa aattcgtgga gattcaagga actggagaag aagcaacgtt tgatggtgaa
    17521 cagttgaatg aaatgctctt ttttggaaaa aacgcgattg aagatttgat caaagagcaa
    17581 aaacatgctt tgctaacaga gtttgctcaa aatgatgagc ggatagaaga aacaaaaaca
    17641 atcatcattg cgacaagaaa tccaggaaaa gcagaagagt ttcgaaatat gttcaaagaa
    17701 gcgggatatc atgtaaaaac attacttgac tatcctgaat tgccagatgt ggaagaaact
    17761 ggcagcacat ttgaagaaaa tgcccgatta aaagcagaaa cgattgcaca attgcttgat
    17821 cagccagtct tagcagatga ttcaggtttg aaagtggatg ctttaggcgg tatgccagga
    17881 atctattctg cacgttttgc aggggaacaa aaaagtgatg cggggaataa cgccaaatta
    17941 ttatatgaat tgacagatgt gccggatgaa aaaagaacag cacaattcca ttgtacgtta
    18001 gtattcgcgg cacccaaaaa agacagcctt gtagtagaag cggaatggcc cggtcgagta
    18061 gcccgtatac catctggcga aaatggcttt gggtatgatc ccttatttat cccagaaggt
    18121 aagaaacaaa cagcagcaga attatcgagc gaagaaaaaa acaagatcag tcatcgggct
    18181 caagcaatga aaaaattgag tgccgagtgg aaacaatggc tggaaggaga gagatagatg
    18241 cggtatttag tagtaagtga taatcatgga gacagagata tcctcgttga cttagtagat
    18301 cgttatcgtt ctgaagtgga tatctttttc cattgtggtg attcggaatt agaagcttct
    18361 gacccattat gggatacatt ccaagtggtt caaggtaatt gtgattatgg accaggattc
    18421 gaacagaaaa aagtgatcca aactggtcag gatacagtat tcatgactca cggtcattta
    18481 tcgaatgtcc gatttggttt gacacagtta gcaatcgaag ctcgagctgc aactgccgat
    18541 atggtgtttt ttggtcatac ccatcaaata ggctgtgaga tggatcagaa aatcctgttt
    18601 ttgaatcctg gtagcatttc tcagcctaga ggcccgatcc aaatcccatc atatgctctt
    18661 atcgaaagtt tagatgacca aatttctgtt caatactata accgtgccca tcaggcagtt
    18721 gaagagttgg ccttttcttt ttcgagagag cgctgaataa aaaaactcta atttttaata
    18781 aaaataagct ttattttatg aattttgcat ccggtttcgg taaaatagta gtgttgaatg
    18841 aaatagaaat ggaggccatc agatgattgg acctatagta agagaaatgc tgctggaaaa
    18901 tcaggaaacg tttttgattc ctgcagaaaa tgtggcaaat gttatgtatc atcatccatt
    18961 gtcccatggt ttacttgtgt tatcgaaggt cggttattcc aaaattcctg tattaggaaa
    19021 agatgatcac tttgtaggac tagtaagttt atcagatgtg gtcaataaaa tgattgactt
    19081 gcaaacaatc agcatggacc cgttagaagg actaacggtt gctgatgtga cagaaacaga
    19141 tgttccgaca attgatgaaa attgggaact agaagaagta ctccatttgt tagtcgattc
    19201 gcctttttta ccggttgtca cagaagatcg gattttcaaa ggaatcatta caagaaaaga
    19261 gctgcttaaa gccgtaaact tcatggtgca tgaattagaa cgtcgtaata tattgtctcc
    19321 gaaaatcgaa gaattaaaag aacaaatcga tatcgtgagc taaagaacga gaaactaaaa
    19381 gataatcaaa aaataagtag aaaaaacagc gtaccagttt tgactttatc ttgaaaaaga
    19441 ggctgggaca aaagcgttta actccaagaa ataagaagga attcacgaaa attgcttttc
    19501 aaatttttgt gaatttcagc ttatttccga aggagttgct tctgcttccg ccgtttatac
    19561 gtgtttagag cgtgggacaa aagtgttctt tacttttgtc ccacgctctt tttagtgaga
    19621 ttcgttgcat cgtttgtcca aattattttc cgacagcaat tggactgttc ggaatcgtga
    19681 aaccagaagc tgtcaattct ttgacatagg agctcaagaa ctcttctttt aaggcatatt
    19741 gttttccgtt caatgcgtag cagaccgtac gaatcgcaaa attgctgttt ccaagatcca
    19801 ctaatccaaa gatagaaggt tcagtttgga gctcttcttg gtatttttca gctaatgtac
    19861 gatttactcg atcaatgatc tcatagattt tgtcatatcc ttcttcagga acaatccgaa
    19921 tatctaaaag tacttgcata tttgcacgag agagattgct gatcgtggtg atgtttcgat
    19981 tcgggatgaa atggacagta ccatccgttg ctttcagctg aagggtacgg ataccaacag
    20041 atacgacggt tccttcaatc gttaagtttg ctagcttgat gtagtcccca acatccatct
    20101 gttgttccat gataataaaa aatccggtaa taacatcact catgaaccct tgggcaccaa
    20161 gaccgattgc cacacctgca attccggcac cagccaaaag tgatccgatc ggcacaccga
    20221 tagcagataa aattgcatag ataaaaaaga aaccaagggt ataatgaaaa atagtattta
    20281 aaagactatg taaagtcttt aagcggctct cgtttagaat ggctttttta gaatactgat
    20341 taaaagactt atcaatcaga tattttccca cacggtgaag aatccaaaaa aggacgatca
    20401 aaaaaatcag atataaactt ttttggataa aggcagccaa aatggcgtcc caatcaatcc
    20461 cgtcccaaaa ccgctgaaac gcatttactt tgctgacagc ttgatctgtc aatgtctcgc
    20521 cagaagagtc tgtcgtaccg gcagttgcta ataatgaaaa cataaaatcc tcttttctaa
    20581 aatttgattc tttctgtatt gtaccaagaa gttttcaaaa aaggaaatag caaaaataac
    20641 tataatgaag gaaaaaagct gaaaataaaa tgacaaataa tatggataat gataaaatgt
    20701 ggagaaaata acgaaggtgg taagtatatg caaatcgatt ggaacaatct aggtttttct
    20761 tatatcaaaa ctccttggcg ttttattgcc aaatggaaag acggacaatg ggaagaagga
    20821 gaattgacag aagataatta cctgacgatt catgaaggct ctccagcgct tcattatggt
    20881 cagcaatgtt ttgaaggtct aaaagcttat cgtcgaaaag acggcaaggt caatctcttt
    20941 cgacctgaac aaaatagtcg acggatgaat caaagtgcta gacgattgct gatgccaatg
    21001 gtccctgaaa agatgttcgt tgatgctgtc aagcaagtgg taaaagcaaa tgaagatttt
    21061 gtgccgccct atggaacagg cgctacatta tacttgcgcc ctttactgat tggggtcggt
    21121 gaaaacattg gtgtccatcc agctccagaa tatttatttg tcgtcttctg tacgccagta
    21181 ggagcgtatt tcaaaggtgg actaaaacca acgaatttta ttgtatctga ttacgatcgt
    21241 gctgctccta aggggactgg tgcagcaaaa gtcggcggaa attacgcagc gagtttactt
    21301 ccaggaacag aagcaaaaga actggattac tcagattgtg tttatcttga tccagccaca
    21361 catacgaaaa tcgaagaagt aggtgcagca aatttctttg gaattacaaa agacggaaaa
    21421 ttcatcactc cgcaatcgcc ctctatctta ccaagtatca cgaaatattc cttgttgcag
    21481 ttagctgaag aacgactagg actgcaagca attgaaggag atattttcat tgatgatcta
    21541 gatcaatttg cagaagctgg tgcatgtggt acagcggctg ttatttctcc aatcggtggg
    21601 atttatcaca ataacaatct tcatgtattt tatagtgaaa cggaagtagg accagtaaca
    21661 aaacggttgt atgatgaatt gacaggtatt caatttggag acatagaagc accagaaggc
    21721 tggattgaag tcgtggaata atttcaaagt aatgagttga aaaaaacgta aaaagaaaaa
    21781 atcaggaaga gactttaaaa agttttttcc tgatttttat atgttttact ttaaagaatg
    21841 caacaaaagt ttatgaaaga tggacacctt tgtcaacgta gataatatca ccgatgattc
    21901 cgctggaaag tgggctgatt aagaaagcac aagcattacc gacttcttcg atcgtcacac
    21961 cttgctgatc aggcgtacga gattcagata actggatcag tttttgatag tctttaacac
    22021 ctgtgacagc taatgttttg attgccccag ctgagattcc attgacccga attcctttag
    22081 gcgagaactc agctgccaaa taacggatag cagcttcaag agaagctttc gcaataccca
    22141 tcatgttata attcgggatt gcgcgttctg aacctagata agtcatgcta acgatcccgc
    22201 tgtttggtgc aagaaacggt tgtgcgtatt ttgatacagc aattaaagag tagctgctga
    22261 tatcttgagc taattgatag ccgtctctgg aaatatcaga cacatttccg gacaattctt
    22321 ctttgttggc gtaagcaact gcatggacaa ggccgtggat ctccccagca tattcaccga
    22381 tggcattcat tgctttttcg atgctttcgt cgctagaaac atcacattct acagtgaatg
    22441 cttcttcgcc gaccaatttg actaatgatt ttttcattcg ttcattttgg taagtataga
    22501 taatttctgc cccttgtttc aacattgctt cagcacaacc ccaagcaatg ctttttttgt
    22561 tagcgacgcc cataatgacg attttttttc cttctagaaa tgacataatg actctccttt
    22621 gtttctgata aaaatttgat agtcgtaaaa aaatagagaa taatagctaa aataacttct
    22681 tgatttctta attattagtc aaaatgtttt gattgtcaaa ctattttttc ttaaattaaa
    22741 aaaagattgc taaatattta ggaatatgat actttgatag tcaaagtaat gaaaatggca
    22801 attgcctgaa agaaggagtt taattatgtc ttacgtatta tctgctactg aagtaatgga
    22861 attgattcct aatcgttatc ctatttgtta tattgattat gtagatactt tagaaccagg
    22921 aaaaaagatc gttgcgacaa aaaatgtaac aatcaatgaa gattttttcc aaggtcactt
    22981 tcctgacaat ccagtgatgc cgggtgcgtt gattctagaa acactggcac aagcaggttc
    23041 gatacttatc ctaaaatcag aagagtttct aggaaaaaga gcttatatcg gtgggatcaa
    23101 taaggccaaa ttccgtcaaa aagttgttcc aggagatgtg ctgaaatgtc attttgaaat
    23161 caccaaaatg aagggatcag tcggtacagc gttatctgca gcatatgtag atgataaaaa
    23221 agtctgtgag tgcgagttca cgttcatcgt caaccaaaat gcttgactat aaaacctgat
    23281 atagcaaaac aaaaggaagc ttacttgctt tttatgtaaa aagaagacgc ctgaatccta
    23341 gcatacgttg tcatctatgc aggattcaga cgttattttt ttatttttgt tttgcttctt
    23401 gcagtatatt gattttatcg atttttactt cttcttttgg tttgtctgaa ctatctgttt
    23461 cgatatttgc aatagcatcc acgacatcca ttccttcaat cacttggccg aagacagtat
    23521 aatggccatc tagtgaagga taaccgccgt ttttataagc gtcgatgatt gcttgaggat
    23581 agtcgtcttt taaaagacca tcatgcatat catctgtatt ttgaacgata aagaactggc
    23641 tgccgttact gttaggatct tgtgagcgag ccatagataa cgcacctctt atattataaa
    23701 ggtggttgtt gatctctgtt tcaaatcctt ctccccaaat gctttcccct ccagtgccat
    23761 cgcctttagg atcgccacct tggatcatga aatctttgat gacgcgatgg aaagtcagtc
    23821 cgttgtagta accgtctttt gcatgtgtca taaagttttc aaccgctttt ggtgcgtgtt
    23881 cgggaaataa tttgattttg attgtgcctt tattcgtcac catttcgacc agatcttcat
    23941 tttcggcgac atctttcgtc aattgtggta attccaatgc gttcaaatcg acgctactgg
    24001 cagtcgtgct ttccgcagta gatgtacttt ttgaactttc tgtagacgaa ctagaagaag
    24061 tcgtgttgtt tgcagaacaa ccagcagcaa acagcaatgc tgctgctaaa ctaatactta
    24121 aaataacttt atttttcttc ataactgttc ctttccaatt tactattttg ttatctttaa
    24181 tgataacaaa atagagggaa aatacctact taaattattg gaatttatca tttattttaa
    24241 aagaaaaaga aaaggtgtag accatttact ttgtgtttgc tataatgtaa gtggatacaa
    24301 aaacgaaaag atgcaggagg aaatggtaat atgggaaaat taggaatctc gatttatcca
    24361 gaacggtcaa catttgaaaa ggacaaagcg tacttggatt tagctcataa gtatgggtat
    24421 aaacgggttt ttaccagttt gctgcagatc aatgatgata aagaaaaagt tctttcagaa
    24481 tttaaagaag tagttgatta cgcgaatagc ctaggcatgg aagtaatggt tgatatcaat
    24541 ccagcgttat ttgaacagtt ggagatttct tacgatgact tatctttttt ccataagatg
    24601 ggtgcctacg gggtccgctt agatatcgga ttcacaggag cagaagaagc aaaaatgacg
    24661 cgcaatcctt ttggtatcaa aatcgagatc aatatgagtt cgggcacgaa ttacgttgac
    24721 aacatcatga gttattcgcc aaacacggat aatttattag gttctcataa tttttatcct
    24781 catcgatact ctggtttagg atacgaacac tttgtttttt gttcagaaaa attcagaaaa
    24841 tataatttga atacgatggc attcgtcaat tcgcaatctg ctgagtttgg cccttggcct
    24901 acgcaagatg gcttgtgcac gctggaagac caccgagatc ttgaaattgc gacacaagtg
    24961 aagcatttaa tccttacagg attgattgat gatatttcta ttggaaatgc gtacgcaagt
    25021 gaagaagaat tgaaagaaat ggcagaagca tttaacgcgg attatccaac attgaaagta
    25081 gatacggaag aaggtattac agaaaacgaa cgaatctgct tgtttgataa ccttcatagt
    25141 tatcgagggg atcgctcaga atatatcctt cgttcaacga tgactcgtgt atactacaaa
    25201 gataaagatt tcccgcctca taatacgcga gatatgcatc atggggatgt actgattgac
    25261 aatgaagggt acggtcaata caaaggagaa acacaaatcg ccttgaagga tatgaaaaac
    25321 gacggacgtg tcaatgttgt aggaagaatc tccgatgacg aattattcct ccttgacttt
    25381 ttgaaaccat ggtcaagctt taaattaatt gaaaataaaa aatagataat tagttattgc
    25441 agaaataatc cgctagaaat agccagttat ttctgctttt ttattttgtt tttttatagg
//
LOCUS       DAPBAF010000043        24337 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.043, whole genome shotgun sequence.
ACCESSION   DAPBAF010000043 DAPBAF010000000
VERSION     DAPBAF010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 24337)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24337)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24337
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.043"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(132..2477)
                     /locus_tag="RD451_002094"
     CDS             complement(132..2477)
                     /locus_tag="RD451_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HDT7567329.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLLFAA
                     LGIGIGAGYFAYLVEDTQLPTKKELQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIVLSAQVEKHFSKNEIITTYLNVSPFGRNNKGQNIAGVQEAAR
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSEAYYQKAQQTIQNKGYTIHSTIDKDIYAALQTGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLVGSES
                     RVSDYATTWQEGKNAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINEKITTPFKDVISSLNGNLGNA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSQARIRSANYLANLINQAY
                     QANPEIFGTDEKFDLSSDVMKKKVSGFTGQTAGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANPETKESDDKDD"
     gene            2756..3658
                     /locus_tag="RD451_002095"
     CDS             2756..3658
                     /locus_tag="RD451_002095"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HDT7567330.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAFMAENGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGAEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKVIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     ISMFKAQAFDPEVFPELLAEEVTL"
     gene            3869..5644
                     /locus_tag="RD451_002096"
     CDS             3869..5644
                     /locus_tag="RD451_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HDT7567331.1"
                     /translation="MLNILNPLIDQLKKKHTYFILGIAVLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIHYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     IFASILVALAFKPIVKNKYLLLSIYFYFLFSPISFTHEYSTRTYRNALVIPAVEIIIA
                     CLLAIYYRKYGSSRKLLPWFLGLSVAFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEVKKLKKRLFLLSKREWLKLSLFLLPIVGFSIVYQWIEYKNETTYGIATIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALAASPTFHTVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYHKGT
                     IKKKKEFYLMGSGDGKTMSDLPIVFDFLQSGYAYAWRYKDFHQGGNYSFGTQEQVKQA
                     QELLNLPLMENWIDSNEPRTPNFQLTKSAKVANVIIKIYQVLAIPVLIASIAGILLMI
                     LGTVFAKADRAYYSSSLIVVTGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIVVTSMLVFSKLNLKKALSSK"
     gene            complement(5710..7296)
                     /locus_tag="RD451_002097"
     CDS             complement(5710..7296)
                     /locus_tag="RD451_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HDT7567332.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVTQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQNEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHAALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFIVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADHIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQLLQETVEEIE"
     gene            7547..7771
                     /locus_tag="RD451_002098"
     CDS             7547..7771
                     /locus_tag="RD451_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HDT7567333.1"
                     /translation="MVSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            7913..9664
                     /locus_tag="RD451_002099"
     CDS             7913..9664
                     /locus_tag="RD451_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDT7567334.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGIFSLFAVALVQLVPPKVIGIIID
                     EIADKNLSIKIISWWILLLILAAFLQYLFRYIWRTNIWGSAARLERELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGRSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     RMWEKQQLEAKIEGGEA"
     gene            9664..11448
                     /locus_tag="RD451_002100"
     CDS             9664..11448
                     /locus_tag="RD451_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7567335.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGVYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYVRVRLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFVAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     ALTLFGIDALHSPVEVGLIYAFTTYVQEFFNPMSQMMDFLSTFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQAITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPAITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLAKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGV"
     gene            11783..12635
                     /locus_tag="RD451_002101"
                     /pseudo
     CDS             11783..12635
                     /locus_tag="RD451_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
     gene            12732..14618
                     /locus_tag="RD451_002102"
     CDS             12732..14618
                     /locus_tag="RD451_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDT7567336.1"
                     /translation="MGKYQELARKIVENVGGKENINGLTHCITRLRFKLKNEEKANDE
                     ILKNMDGIVTVMRAGGQYQVVIGNHVPVVFEEVIKAGNLTFDEAVSTEKMRPFDMLID
                     GISGCFQPFLAILAADGMIRGLTAFLVFLGAFDRGSGTFVMFDNIGDSVFQFMPVIIG
                     LTAARKFKVNEFVGMLLGAALMNPSLSLEALSGAAEAPLTTIFSGTIFEAPIYQTVFG
                     IPWIARNYASSVIPIIFIVLLASQIQKPIKKLVPEMIANFFVPFFTVLITMPLGFLLV
                     GPVFTFATDILMAGFETLLALSPVIYGAIVGFFWQILVMFGLHWAIVPMGLMQFSVNG
                     WQNIMTPVAVVSFGQTAALTALYFKLRNPKDKAIAIPAIVSGIVGITEPAIYGFTLPR
                     KKIFIFTCVGGALGGAYSGLMNLTSWNQGGLGIFTIPNYIRPDGDLTDVINVLIGIAI
                     AMVVSFALTFFFWKEEADETDDRQKRSGKEIVKTPIQGQIAPLNAAKDAAFAQGTLGR
                     GILIYPEKGEVRAPFDGTVMSLFPTKHAIGMVSEAGLELLIHVGLDTVQLEGKYFESL
                     VQQGERVKQGDLLLRFDKKKIEEEGYSLETPVIVINYMDYLDILENQGETVGPDDALI
                     TALT"
     gene            complement(14659..15561)
                     /locus_tag="RD451_002103"
     CDS             complement(14659..15561)
                     /locus_tag="RD451_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDT7567337.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQEIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIQDTLSLIHHDQLQKAKQLMLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNHVPILALTSIGDST
                     LSSMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVD"
     gene            15791..17194
                     /locus_tag="RD451_002104"
     CDS             15791..17194
                     /locus_tag="RD451_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HDT7567338.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMAMMTEPTMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     ELIDRLYDEDNGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLPADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMDELFIAHQQYLPQFKETISRLKAEGIEVQ
                     DELARELSSNTHVMEEV"
     gene            17191..18627
                     /locus_tag="RD451_002105"
     CDS             17191..18627
                     /locus_tag="RD451_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HDT7567339.1"
                     /translation="MMGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGEDRFP
                     VITGKKKMFEFDENHFYPAKIAIDMYHHYKEDIALFAEMGFKTYRMSIAWSRIFPMGD
                     EKEPNESGLKFYEDVFKECQKYGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENL
                     CRVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEEGENEEQIKYQAAHHELVASA
                     IATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPA
                     YALKEMERNGIQIKMEPGDAALLKEHTVDFISFSYYSSRVSTTDNELLEQTAGNIFAS
                     VKNPYLEASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDY
                     RIDYLAAHIQAMKDAVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNEGN
                     GTLARSKKKSFNWYKKVIDSNGENLSND"
     gene            18772..19698
                     /gene="trxB"
                     /locus_tag="RD451_002106"
     CDS             18772..19698
                     /gene="trxB"
                     /locus_tag="RD451_002106"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HDT7567340.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYEGVSRFGTENAYGIVQDIKDHGSHKEVICEDKTYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNIPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            19911..21638
                     /locus_tag="RD451_002107"
     CDS             19911..21638
                     /locus_tag="RD451_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HDT7567341.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLNDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDDEAEHSGLITIIGEEVDAAYLEEIKAV
                     TIDHELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAMRLGEKEGADLLIATDPDADRLGAAVRLPNGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYYAEKTISVTMSGQEGSAKISALMEKFREEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGNSSEDAAEKVAAYE
                     AIIKKMTEE"
     gene            21654..22004
                     /locus_tag="RD451_002108"
     CDS             21654..22004
                     /locus_tag="RD451_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDT7567342.1"
                     /translation="MEKVVNFRSQSFFKLEVNGLPDTQKTKVEKVSQLFKMLSDPTRL
                     KILLYLKDGEQNVTAITQAVEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHV
                     LDILNQTLKHVEHQ"
     gene            complement(22098..22958)
                     /locus_tag="RD451_002109"
     CDS             complement(22098..22958)
                     /locus_tag="RD451_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HDT7567343.1"
                     /translation="MSSDSTEIITFFVISDSAGETATKLAQATMAQYPTVEFNLFRRT
                     FVTDEKTLMQALQDALKEKALVLHTLINQELIEMTRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEETD"
     gene            23050..23478
                     /locus_tag="RD451_002110"
     CDS             23050..23478
                     /locus_tag="RD451_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HDT7567344.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            23640..23816
                     /locus_tag="RD451_002111"
     CDS             23640..23816
                     /locus_tag="RD451_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HDT7567345.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            23843..24289
                     /locus_tag="RD451_002112"
     CDS             23843..24289
                     /locus_tag="RD451_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HDT7567346.1"
                     /translation="MSLLSRLNDDMKTAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
BASE COUNT         7708 a         4353 c         5186 g         7090 t
ORIGIN      
        1 gtttttcaca tttttacata aatttgtctt aatatcgtag atgtaagctt ttgaacacca
       61 tttattcgga aaaagggagc tgtgacaaga tttttgtcgc agctcccttt aattctgatt
      121 aatctattag atcaatcatc tttatcgtct gattctttgg tctctggatt cgctctagca
      181 taagctgaag cggtgttcca gtaatctgta tagttttcat cagtaccgcc tacgccgaat
      241 ttaaaggcgc ttttcttcgg accatttttt gcccaaagtg actccactgt ttttcctggc
      301 gtttggatgg attttttatt gacagtaact tttccagctg tttgtcctgt gaacccagat
      361 acttttttct tcatcacatc ggatgataag tcaaatttct catcagtgcc gaaaatctca
      421 gggtttgctt ggtaagcttg attgattaga ttggcaagat aattagccga acgtattctt
      481 gcttggctgt ccattccagt attgtcatcg tgtcctgccc aactactgat agtgatagat
      541 ggagttgaga cgatcagcca tgaatctcgg tattcattgg tagaaccagt ttttccgacc
      601 caatctgcat ttcctagatt tccgtttaag cttgagatga catctttgaa tggtgtagtg
      661 attttttcat tgatcacact acgcatcatg tcattcatga tcgatgccgt tgcttcggaa
      721 taaatacgga cagaattact ttcatgttta taaatcacat tacctgcatt atctgtgatg
      781 gaatcaatga tatagccttc ttcgtagact ccaccatttg ctaaggcctg gaatccattt
      841 gtctgttgaa gcgtcgttac atctactgtc cctaaaggag ccgattcaac gccccaatta
      901 tcatttgctg ggtagttcat cttcgccaag tagtgctcgt aagcgtattg tttcgatcca
      961 ccggaattca acacatcttg atataagtga taagctggga tattgttgga ccattccagt
     1021 gactcacgga cggtttggaa ggtgttcgac ccttcattgg tcgcattgac gattttctca
     1081 ccagcatttt ttccttcttg ccaagtcgtt gcataatctg atacacggga ttctgatccg
     1141 acaagtccca tatcgattgc aggaccgtaa acaagaaccg gtttgatgga tgaaccagct
     1201 tgacgttctg tatcaaaggc gtggttattt tgattctggc tgtaattccg accacccacg
     1261 aagccataga tacgtccggt tctgttatcc atcaatacat ttccagtctc cacttggcta
     1321 ccagcaccat catctaacat gtagccataa ttttctacgc cggtttgtaa tgcagcatag
     1381 atatctttat cgatcgtcga atggatcgta tatcctttgt tttggatcgt ttgctgtgct
     1441 ttttgataat aagcttcact gaccgatgaa tctgacatat cagcattatc tttttctgcc
     1501 aattgttgtg caataatcct tgttgcttcg ttcatcacgg tataatacaa gaattctctg
     1561 tcagtctgtt ccgcgatttg ttgtgggaga aagtcttttg taagatcata ggctttcgct
     1621 tcttcgtatt gttctttcgt aatttgtcct tcacggtaca tactgaataa aacaaaatct
     1681 tttctggcaa gaccggcaga aagatcttct tttagcgcgc ctgtattcgt gtatggacta
     1741 tacgtgatag ggctttgagg caaaccagcg atataagcag cttgtggcag agtcacatcc
     1801 tttgcatcta caccaaagat tcctctagca gcttcctgga ctccagcaat attttgcccc
     1861 ttattattcc gaccaaatgg tgagacattc aaatacgtag taatgatctc attttttgaa
     1921 aagtgttttt ctacttgtgc agaaagaacg atctcgtttg ctttacgttt gaatgttgtt
     1981 tcatcggtta ggatctgttg tttgactaat tgctgtgtca aagtggatcc tccagacgag
     2041 ccgatgccag tcgcttctga aactagtgct cgtaaaacag ctttagggac ataaccttga
     2101 tgtttatcga agtattcatc ttctgtactg ataatcgcgg ttttcaataa aggcgaaatc
     2161 ttatcagatg aaatagtcgt ccgcatcaga tctgtctgga tttttgatat ctctgtatta
     2221 tctgcataaa caatctttga cgtttccgta atgtttccta gttctgtctg cagttctttt
     2281 ttagtcggca attgtgtgtc ttcgacaaga taggcaaagt agccagcacc tattccgata
     2341 cctagagctg cgaacaacaa aagaagaaca gtaataaaaa cagtcaatga ttgaaacact
     2401 ctaaaaataa tcttaggaac aaaccatttt tctttttttc ttctattctg tttttttcga
     2461 gtatttttgc gtggcaaaag ggtcacctca actaatggtt ttatttcgct aattatagca
     2521 aataatagga caaaaaaaca gacaaggctg tttttgacag gaatttcttt ttcgaatgag
     2581 ataaaacgtg aggaaatgat cttttttatg aaagagttct taagcttttc tttagggaaa
     2641 gtttcagtta ctatggagaa cagggcaaag aaaaacaaac cattttcttt gtacatcatc
     2701 ttatcaatat acaggaattg ttcgaaacaa ttgcctttca aggaggaatc catccatgtt
     2761 attaggctca catgtcagca tgagcggaaa gaaaatgctg ttaggcgcgg cagaagaagc
     2821 agccagttac ggatcttcga cctttatgat ctatacaggc gctcctcaaa atactagaag
     2881 aaaagctatc gaagagatga atattgatgc cggaaaagca tttatggcag aaaacggact
     2941 aacaaatatc gtcgttcatg cgccttatat cattaatttg ggaaatacga tcaaaccaga
     3001 aatgtttcca tttgctgtac aatttctgag agaagagatt gtccgtgcgg aagctttagg
     3061 tgctactcaa atcacccttc acccaggcgc tcatgtagga gcaggggcag aagctgggat
     3121 tgctagaatt attgaggggt tgaatgaagt tttgacaaaa gaacagacgg cacagatcgc
     3181 tttggagacg atggcaggga aaggtacgga aatcggtcga acatttgagg aattagcgca
     3241 aatcatcgat ggagtaaaat tgaatgaaaa attatccgtt acttttgata catgtcatac
     3301 gaatgatgcc ggatataata taaaagaaga tttttcaggt gtaatggaag agtttgataa
     3361 ggtcatcgga ttagatcggc ttaaagtact gcatatcaat gattctaaaa atccacaagg
     3421 ttctcataaa gatcggcatg ccaatatcgg ttttggaaca attggatttg acacattgaa
     3481 caaaatcgtc catgatccaa tgtttgacaa catttcgaaa atattagaaa ccccatatgt
     3541 cggtaaagat aaaaagaaag cttacgcacc atatggaaaa gaaatttcca tgttcaaagc
     3601 gcaagcattc gatcccgaag tgttccctga gttattagca gaagaagtca cactttaagt
     3661 tttctacctg acagcaacaa aaaaggattg ggcagtctgc cttgtccttt tttgtttaag
     3721 aaacaaagga gtgctttttg cattcgtttt cgccatgctc cttttgcccc ctctttttaa
     3781 attcagacaa acagggtata ctgatagaaa agtaaaaaac gaaaagtttc acaaacaagt
     3841 agcaaaacgt gattgaaagg acgaaaagat gctgaacatt ttaaacccct tgatcgacca
     3901 actaaaaaag aaacatacat actttattct tggcatagcc gtattattta caattattcg
     3961 gttgtattta tatagtaaag caatctatgg aacagatatg tcggcgacct atgatgatca
     4021 gctgctgatt cactatgctc aaaatatttt ggatggtaaa tggctagggg agtatacgac
     4081 tacaacactt tccaaaggaa tctcctacag cttattttta gtacttgcac ataaactgca
     4141 tctttcttat gcagttttgt tcggcatgtt cagtattttt gccagtatat tggttgcact
     4201 cgcgtttaaa ccgattgtga agaacaagta tcttctttta agtatctatt tttatttttt
     4261 gttttctccg attagtttta cacatgaata ttccactcga acatatcgta atgccctcgt
     4321 gattccggct gttgagatca ttatcgcttg tttattagct atttattacc gcaaatacgg
     4381 ttctagcaga aaattgctgc catggttttt agggctttct gtcgcttttc ctttcttttg
     4441 gttcattcgc gaagattcta tctggcttct tccttttact gtagtagctt tgggtatcag
     4501 tttcgtccag atcttgctag ggcaagactt ttctttcaaa gaagtaaaga agttaaaaaa
     4561 acgactcttt cttctctcga aacgggaatg gctgaaactt tcattgtttt tacttcctat
     4621 agttggcttt tccatcgtct atcagtggat cgaatataaa aatgagacaa catacggtat
     4681 tgcaaccatc aatgaccgtt ccagtggaga atttggacgt ttgatgaaac aactgatccg
     4741 aatagatgat gaaacgaact tgaataaaga aaacagtgag atatgggtct cacatgctgc
     4801 actaaataaa gcattagccg catctcctac attccatact gtttctaccc gtattgacga
     4861 attatatacg actcacgcgt ggactcaagg tggaaaagta aaagaattac ccggagatat
     4921 catcttttgg gcattgcgag atgtggtaag cgaatctggt tattaccaaa acaatgcaaa
     4981 agaaaccaat gatttttgga aaaaagtcaa ccaagaatta gaagaagcct atcacaaggg
     5041 aaccatcaaa aagaaaaaag agttctatct gatgggatca ggagatggaa agacgatgag
     5101 tgatctgcca atcgtattcg atttccttca atcaggatac gcttatgcat ggcgatataa
     5161 agatttccat caaggaggaa attatagttt cggaacgcaa gaacaagtca aacaggctca
     5221 agaattatta aaccttccgc taatggagaa ttggatcgat agtaatgaac cgagaacacc
     5281 taatttccaa ttaacaaaat cagcaaaagt cgcgaatgtc atcataaaaa tttaccaagt
     5341 tctggctatt cccgtgctga ttgcttcaat agcagggata ttacttatga tactaggaac
     5401 cgtatttgca aaagctgatc gtgcctatta tagttcctct ttgattgtgg tcaccggatt
     5461 aatactgaca caattggttt ttcttttcgg tgtctcatgg ttttgttctt atgcgccaga
     5521 aaaaaaggac tattttttaa gtgtctacac tggtgcaggc gtgccattaa cgcaattcat
     5581 cgtagtaaca agcatgctag ttttcagtaa attaaatctg aaaaaagctt tatcttctaa
     5641 ataaaaagac ccttggtagc tagattttta acctaactat caagggtctt tgtgtggaaa
     5701 aatcagtttt tattcgattt cttctaccgt ttcctgcaaa agctgttcat attttttgtt
     5761 tcctttatat aaatcaccaa tcgtccatgc caacaggaga aggacaagaa caatgattac
     5821 ataagcgatg tgatcagcca atgctagttg agcggaagtg gcttgctcgc cgaagaaact
     5881 ttcgatctgt cctggtaatc ctcgtaagtt caagtaagtt agactaatca cagagaacca
     5941 gccaagaagt tttacgatga atgaattttt aaatcggcta cccatctccg cttggctgtt
     6001 ggtcatcatc agtaaaggaa tcatcgaaaa tggcaacgca aaagccaaga acacctggga
     6061 ttcattcatt aagttattca aagcggcatg ttcttcgatc gttccttttg tacttgtaaa
     6121 caaaacacaa atcaatacag gaatcacaga aagcaatcgt gtgaccagtc ttcttagcca
     6181 aatcgggata cgcatatgga tgaatccttc catgatgact tgaccggtca acgtaccagt
     6241 aatagtagag ttctggccag aagcaagaag tgctacagca aataaagtgg acaagatacc
     6301 agattttgct acagcaatca aaataccatt gctcatagct gatggatcag ataaagcttc
     6361 atacagacca aaaaaggaag gatcttggac agaaccggtt ttgaagacag cgacacccat
     6421 gatcaatagc agtgcattga ctagaaaagc cattgacaac tggatattag aatcccaagt
     6481 agaaaaacgt acagcttgtg ctacatcttc ttcgttttgg tgatcgatct tccgagtttg
     6541 tgaaactgct gaatgaagat ataagttatg cggcatgact gttgcaccaa taatccctaa
     6601 agctccagtc agcggagttt cgccgccgat gaccggtgag tctgagaatg tatgactgtt
     6661 agggataaag ccagcaaata aactgtgcca atctgggtta gacaagccaa cttgatagac
     6721 aaaaacgaat aaaatgacga aaattaagca gacaaccagt gcttcgatct tacgaaaccc
     6781 gacttttgtc agtagtaaga gaacgaaaac atctaataca gtaataaaga cggcaatcac
     6841 caatggaata tcaaaaagta agtagagggc gattgctgca ccaatgactt ctgcgatgtc
     6901 tgttgccata atggctaatt cagtcaagat ccataaaatg acacccaatg tcttacttgt
     6961 ccgtgctcgg attgcttggg ccaaatccat ttgggtcacg attcctaatt ttgctgccat
     7021 atactgtaaa agcatagcaa ttagactaga catcaaaata actgacatca ataaatattg
     7081 gaaattttgt ccaccagtga tcgaagtgga ccagttacct ggatccatat aaccaactgc
     7141 tactaatgca cctggtccag agtaagcaag aagtgtttta aaaaaacttt ttccctttgg
     7201 tacatccact gttccattta cttcagctaa agataaacca tttgtatgtt caataagtcg
     7261 atgcttatga aattgtttgt tggattgatt attcaagaaa aaaccacctt tcctatttat
     7321 ctacgattac attctacacc tcagaaagaa aaaattaaag aaaaagattc ggtatgccta
     7381 attttttttc gtggtgtgtc ttgctggtta atgaaagaaa ttttgttctt ctctaaaaaa
     7441 accactattt tttgcatgaa actaaagaat acgcctttct tttttcaata aactttagta
     7501 aaataaatca ttgagagcaa ttcggaaata gaaaggagag atttatatgg tatcaacagg
     7561 tattgtcgta cttattgcta ttattgcttt gctaatcggc gcagtaggtg gctttttcct
     7621 agcgcgtaaa tatatgaaag actatttaga aaaaaatcct cccgttaatg aggacatgtt
     7681 gcgatcaatg atgatgtcaa tggggcaaaa accatctgag aagaaaattc gccagatgat
     7741 gcagcaaatg aagaaccaag ggaaaaaata ggttctgacc caaagacttt ttgcgggctg
     7801 attttttcag tccgtttttt atttcgtaat ttgttagact attcagacta ttcagcaaaa
     7861 aagacaagca cagacaatcc tatgctcttg ataaagacaa aggaggagta aaatgtcgat
     7921 ttttagaaaa ttaggttggt tttttcgtca ggaaaagaaa cattatttaa ttgggatttt
     7981 ctccctattc gcagtggcct tggtacagtt agttcctcca aaagtgattg ggatcatcat
     8041 tgatgagatc gccgataaga atttatcaat aaagatcatt tcctggtgga tcttattatt
     8101 gatccttgca gctttcttac aatatctttt tcgttatatc tggcggacga atatttgggg
     8161 aagtgcagct cggttggaga gagaacttcg gcagcagcta ttcaaacatt ttacagaaat
     8221 ggacaatctc ttttaccaaa aatatcggac tggagatttg atggctcatg caacgaatga
     8281 tttgaatgca atccagaatg tagcaggagc tggaatcttg acctttgcag attcagtgat
     8341 tacgggcgga acaacgatca ttgcgatgat tttgtttatt gattggcgct taacactgat
     8401 tgcgctgatt cctctgcctt tgctagccgt tacttcacga gtgctggggt caaaactcca
     8461 cgatgctttt cgtgattcgc aagaagcttt ttctagtatc aatgataaga cacaagaaag
     8521 tatcactggg atcaaagtca ttaaaacatt tggacaagaa aaagaagatc tcgcggattt
     8581 tgaagaaaag attgaagatg caattattaa aaacaaacga gtcaattttt tagactcctt
     8641 atttgatcca ttcattacct tgattatcgg tctgtcttat gttgcaacaa ttattttagg
     8701 tggaaagtat gtcttggaag gcacgatctc aatcgggcag atggtctcat ttattagcta
     8761 tatcggtatg cttgtttggc cgatgtttgc gattggtcga ttgttcaacg tattggaaag
     8821 aggaaatgct tcttatgatc gcgtcaatga acttttgcat gaaaagacgc atatcgtgga
     8881 acaactgggt gcagtgcaga ccccggcaaa aggcgagctg aatgtagcta tttcctcttt
     8941 taactatccg aaagaagaat caccagcatt agaacaaatc aaatttgcga tccaagaagg
     9001 agaaacatta ggtattgttg ggaaaactgg tgcgggaaaa acgacaatca tcaaattact
     9061 gatgcgtgaa tacgatgatt atcaagggaa aatccaattt ggcggacgtt cgatcaaaga
     9121 atattcattg aatgctttat taggatcaat cggttatgtg cctcaggatc acttcctgtt
     9181 ttcgatgacc attcgagata atatccgttt ttctaatcca aaactttcag aagaagaagt
     9241 agagcatgcg gcttctttag catttatcaa caatgaaatc aaggaattgc caaaaggtta
     9301 tgatacctta gttggagaac gtggagtctc tttatctggc ggacagaaac agaggatttc
     9361 gattgctcga gcattgatca aaaatcctga attgctgatc ttagatgatg cactttctgc
     9421 agtagatgcc aaaacagaag aagctatctt gcataattta aaagaaataa gaaaagagaa
     9481 aacaaccatc attgcagctc accgtttaag cagcgtgatg catgcaaaag aaatcattgt
     9541 tgtcgatcaa gggaaaatca ttgaacgagg aacccaccac gagctgcttg cattaggtgg
     9601 ctggtatgaa cgaatgtggg aaaaacagca attagaagcg aagatagaag gaggcgaggc
     9661 ctgatggatg aaaattatca atcggaatgg acaaaatcga ttccacttaa agaacagaag
     9721 aagatcatca aacgactgat gaagttcgcc aaacctttta gaagaacgtt catcgttgct
     9781 atcttatttg cgtttgccct gtctgtgatc aatgtcctat tgccaaggat catccaaact
     9841 tttatggatg atcatctggc taaacagtca gctacgacac aagttatttt gttttttgct
     9901 ggtgtgtact tgtttggagt catagtcaaa agtatcattt ggtttttcca atggtatttg
     9961 tattccatgg cttcattgaa gacctatcag tatgttcggg taagattatt tgaaaagctg
    10021 catacactag gtatgcgtta ttttgaccag acaccggcag gatcgaccgt ttctcgagtg
    10081 acgaatgaca cagaaacgct atttgaattt tggtatgtct ttttgatggt attgactggg
    10141 atctttgcag tcgtttcttc tttcgttgcc atgtttcaaa tcaatggaga aattgccttg
    10201 tggactttgg tgttcttgcc gattttagga atcgtcatct ggtattacca gaaattcagt
    10261 tctcgtattt accgaaatat gcgggaaaaa ttaagtcagc tgaacacgaa attgaatgaa
    10321 tcgatttccg gcatgcgtat tatccagcag tttcgccaag aagctcgttt agctaaagaa
    10381 tttgaacaag tgaacaacga gtatttagac acgcgctatg cgatgatcaa aacgaattcg
    10441 attctgttaa gtccaatcat caattttctc tatgcattgg cgattgcgtt ggcgttgact
    10501 ttgtttggga tcgatgcgtt gcattctccc gtagaagttg gactgatcta tgcatttacg
    10561 acctatgtcc aggaattttt taatccaatg tctcaaatga tggacttttt gagcaccttt
    10621 acagatggga tggttgccgg tagtcgtatt ttgaaaatca tggatacaga agaatatgca
    10681 ccgcaacaaa atcctggagc agatcaagcg attacttcag gtaagatcga gtttcgcaat
    10741 gtaagctttt cttatgatgg agagcacaat gtattgaaca atatctcttt tgtcgctaat
    10801 ccgggtgaga ccgttgcatt agtggggcac accggaagcg gaaaaagctc gatcatcaac
    10861 gtattgatgc ggttttacga attttatgaa ggccaaatct tgattgatga tcatgacatt
    10921 cgagaatatc caatggaaga gttacgtaag aaaatgggat tggtcttgca agatgccttc
    10981 ttgttttatg gagatattgc aggaaatatc cggatgatga atccagctat cacagacgaa
    11041 cagattcgcc atgcagctga gtttgttcaa gcaaacaagt tcatcgatga attaccaaaa
    11101 ggatatcact caaaagtgat cgaacacggt gccagctatt ctagtggaca acgacagctg
    11161 atcacttttg cgcgaacaat cgtgacagat cctaaaatac tagtattgga tgaagcaaca
    11221 gcaaatatcg atactgaaac cgaaggattg atccaagaag gattggcaaa aatgcgacaa
    11281 ggacggacaa cgatagcgat tgcccatcgg ctgtccacga ttcgggatgc agaattgatt
    11341 ttagttttag acaaaggtca tatagtagag cgtgggaatc atgaaacact tctagcgcaa
    11401 aatggtttgt atgcagatat gtacaaactg caaagcagtg gtgtgtaaaa agaggttgtg
    11461 acagtagcat agtagcattt tgccctaagc gctagagtga aaataaaaca gagcttcgca
    11521 gattcttcat ctgtgagcgt tagtggcgta gtcacccgat ttaaaaaaga cgacgacagc
    11581 tagtcaaaag cggctaataa ccactaagaa agcgttgaca aaagcgtttg ctttcgataa
    11641 tataaagaaa acgatacaac ttggatagtg attgcctgat gcaagctaaa cctgatgagt
    11701 ctcccatggt tccatggacg gctttttggg tttttctttt tgttttggat acagccctat
    11761 atatcatgga aaggagcaaa acatgctgat tgagaaagta ctgaataaca acgtcgtaat
    11821 aaccagggat gaaagaaatc aggaaatgat cgtgatggga aaaggtttgg cattcaaaaa
    11881 gaaagtgggt gacccgattt ttgactcatg catcgacaaa aaatttcagt tgacaaatga
    11941 cgggctttca caacagttcc aagaattggc acaagcgatt cctcttgagt acttagaaat
    12001 ttcttgtgaa atcattgaat atacaaaaga ggctctacaa gtccagttga atgattctgt
    12061 gtatattgca ttgacggatc atttgtatac ggctatcgaa cgtcacaaaa tgggaatatt
    12121 tgtaccaaat gtattgctgt atgatatcaa acaactattt cctaaagagt atgccatcgg
    12181 gaaaaaaaac agtgaagaaa atctcggata aataccacat caagttatca gaagatgaag
    12241 ccggatttat cgcattgcat ttagtcaatg cacaaggcat tcaaagccaa caagacaata
    12301 cctacctgtt cactataaca atacaggata ttctaaatat cgtccgctat tactataaga
    12361 ttacatttga tgaagattca gtccattttt ttcgattcgt cacacactta cgtttttttc
    12421 tgacacgcgt cctagatgga gaaaaatcag aagtgggaga agtttctgag gaattgtttc
    12481 aggttattca aaaaaaatat aaggatacgt ttggttgcgt tgagaaaata gcagactttt
    12541 tagccgagac gttcaactac cagatgtcca cggacgaaaa aatgtattta acgatccata
    12601 ctgcgcgttt agtgcatgag aatcgttgta aataaataaa aaaaggagga taaattaaca
    12661 agaacgtatg aaataagggt agtgacattc agttggctaa accttccact aataaattgg
    12721 agggaataga aatgggaaaa taccaagaat tagcgagaaa aatcgtagaa aatgtcggcg
    12781 ggaaggaaaa tatcaatggt ttgacacatt gtatcacaag gcttcgtttc aaattaaaaa
    12841 acgaagaaaa agcaaatgat gagatcttga aaaatatgga cggtattgta acggtaatgc
    12901 gagcgggagg gcagtatcaa gttgtcatcg ggaatcatgt gccagtcgtg tttgaagagg
    12961 ttataaaagc aggaaacctt acttttgatg aggctgtttc aacagaaaaa atgagaccgt
    13021 ttgatatgct tattgatgga atatcgggct gtttccaacc attccttgct atcctagctg
    13081 ctgacgggat gattcgtgga ctgacagcat tccttgtctt cttaggcgcg tttgaccgcg
    13141 gttctggcac atttgttatg tttgataata tcggtgattc tgtattccaa tttatgcctg
    13201 ttattatcgg tttaacagct gcccgtaaat ttaaagtaaa tgaattcgta gggatgttgc
    13261 ttggcgcagc attaatgaat cctagcttgt cgctggaagc tttgagtggt gcagcagaag
    13321 caccactaac gaccatattt tctggcacta tttttgaagc acctatttat caaacagtat
    13381 tcggcattcc ctggattgcg cgtaactacg cttcttctgt cattcccatt atctttattg
    13441 tgttgttagc tagccaaatt cagaaaccaa ttaaaaagtt agtacctgag atgatcgcga
    13501 atttcttcgt tccattcttc accgttctta ttacaatgcc tttaggtttt ttactcgttg
    13561 gaccagtatt cacattcgca actgatattt taatggctgg atttgaaaca cttttagcac
    13621 tttcgccagt tatttatgga gcaatcgtag gcttcttctg gcaaattctg gtgatgtttg
    13681 gtctccattg ggcaatcgta ccaatgggat tgatgcaatt ttctgtgaat ggttggcaaa
    13741 atattatgac acctgttgca gtagtgtctt ttggacaaac tgcagcactt accgcactct
    13801 actttaagct tagaaatcca aaagacaaag caattgcaat accagccatt gtttctggta
    13861 ttgtggggat tacagagcca gctatttatg ggtttacatt gccacgtaaa aaaatattta
    13921 tttttacctg tgtcggtggt gcgttagggg gcgcgtatag tgggttaatg aatttaactt
    13981 cttggaatca aggtggacta ggcatcttta caattcccaa ctatattaga ccagatggtg
    14041 atttaacaga tgtgattaat gtattgattg ggatcgccat tgcgatggtg gtatcctttg
    14101 cgctgacttt tttcttttgg aaggaggaag cagatgaaac agatgataga cagaaaagat
    14161 caggtaaaga aattgtaaaa acaccgatac aaggacaaat cgctccactg aatgcagcaa
    14221 aggatgcagc ttttgcacaa ggaacactag gtcgaggaat cttgatctac cctgaaaaag
    14281 gagaagtacg tgcccctttt gacggaacag tcatgtccct gtttccgacg aaacatgcaa
    14341 tcgggatggt ttctgaagca ggtctggaat tgctgattca tgtcggattg gatactgttc
    14401 agttggaagg gaaatatttt gaaagcttgg tgcagcaagg agaaagagtg aaacaaggcg
    14461 atctgttgct tcgcttcgac aaaaagaaaa tcgaagagga aggatacagt ttagaaacac
    14521 ctgtgattgt catcaattac atggattatt tggatatttt ggaaaatcaa ggggaaacgg
    14581 tcgggccaga cgatgcactt atcaccgcac tgacctgaac ggttaggtga aagaatggac
    14641 taggcttaac tattcttttt agtccacttc tttattttca aaattgaaag gctctttcat
    14701 gatggctgag ctgatagggc gtttatcaaa tttttgtcct acagaaatta gatggactaa
    14761 attctgttga taattttctg caaaaacaca actatataac acgtctagaa gataacaaat
    14821 cgatgtattg atcgtaaaat taccaatttt cgaatacagt cgttcgcgtg tcgtaagtcg
    14881 caaagcggct gtactcattg aagatagcgt tgaatcaccg atactggtca aagctaaaat
    14941 tggcacatga ttttgtttca atatttctgc ggtacgaagg atcacattgt tttcacccgt
    15001 ataagaaatc agaatcccac acatatcact tgtgcaattg tacgcttcat agaacgattc
    15061 accaaaagtg gtgacaatcg tgacatccat tttgatgcgc ttcattttca gcatgaaatc
    15121 ttgagaaatc aaagtattcg agttactggc gaaaatcacg attttttttg cttgaagcat
    15181 tagttgtttg gctttttgca gttggtcatg atgaatgaga gaaagtgtat cttgaatcgt
    15241 catctgttct aaagaagcca ttttatttgc gatcgtcata ataccgtctg tggtggaaaa
    15301 aggaagattc gcatctacgt cttgaaaatt cccttcaaga taggctgttt cagctaaaaa
    15361 agcattacga aaactgaccc agccatcaaa acccattttt tttgctacac ggatgagtgt
    15421 ggacgggtgg acataacatc gctcagcaat ctcttggatg gtcatttcgc caagtgctgg
    15481 agaatcgctt aagagaaact gaatcacttc attttctgaa ggagaaaagg agatttcttt
    15541 gattttttca cgtaataaca tgtagatacc ttcttcttgt ttttttacgt aaatcataac
    15601 ttttttgaaa atgatttgta aacggattta tgttatatag cttaataaag acattttttg
    15661 acaagatatt tacaaaaatc cagaagaaaa cactaacttt tgtaaatgtt actggaaaga
    15721 aacgaatttc tattgtttgt tttgtttaca aaaaagataa taaaagtgta aaaagtaaag
    15781 gagtgagaac atggcaaaag gaatcaaaat cgctacgatt ggtggaggca gcagttacac
    15841 ccccgagttg atggaaggat ttatcaaaag atatgaggaa ttaccgatac gagaaatctg
    15901 gctcgtagat gtagaagaag gaaaagaaaa gcttgagatc gtcagtcaga tgtctcagcg
    15961 tatgtgggat gcttctccgt atgaagtcaa aatctatgca actctggatc gggaagaagc
    16021 attgaaagat gcggattttg ttacgactca gtttcgtgtc ggtcaattag atgcacgaat
    16081 caaagacgag cggatcccta gttattatgg gatgattggg caagaaacaa atggtgctgg
    16141 cgggatattc aaagcttttc gtaccgttcc agtggttttg gcaatcgttg aagacatgaa
    16201 gcgtttatgt ccaaatgctt ggctgattaa tttcgcgaac ccaagcggga tggtgacaga
    16261 agcagttatc agatatggca aatgggataa agtgatcgga ttatgcaatg tgccagtaat
    16321 ggcgatgatg acagaaccaa caatgcttgg caagaaaaaa gaagagctga tctacaagtt
    16381 tgccggtcta aatcacttcc attggcacaa agtagcagat aataaaggaa atgaccgcac
    16441 ggcagaattg attgatcgtt tatacgatga agacaatgga ttgccgaaaa atatctttga
    16501 catcccgttt ttcaaagaac aattaaaaca aatgaacatg atcccttgtg gctaccaccg
    16561 ctattactat cgtgaagaag aaatgctgga acatgcttta gaagaatatc aaacgattgg
    16621 tacaagagcg cagcaagtga aagaaacaga agcagagctg tttgaattat acaaagatcc
    16681 agaattggat cataaacctg aacaattgca aaaacgaggt ggtgcttatt attcagatgc
    16741 tgcctgtgaa acgattgctt cgatctatgg aaataaagaa acacagatcg tggtatctac
    16801 aaagaatgat ggagctgttc ctgatctgcc ggcagattgt gtagtagaag tcactgccta
    16861 tgttggcgca caaggcgcac gaaatgtagc gtttggttcc cttcctgctg ctgaaagagg
    16921 ctggttgcaa gtaatgaaga atatggaatt gctgacgatc gaagcagccg tgactggtga
    16981 ttatggaaca gctttgcaag cgtttacgat caatccgctt atacgatcag gaaagacagc
    17041 aaaacggatc atggatgagt tgtttattgc acatcagcag tatttaccgc aattcaagga
    17101 aacaatcagc cggttaaaag cagaaggaat cgaagtccaa gatgaactgg caagagaatt
    17161 atcaagcaat acacatgtaa tggaggaagt atgatgggat tcagaaaaga ttttttatgg
    17221 ggcggagcta cagcagccaa tcaatgcgag ggcggttatg atgaaggcgg acgtgggtta
    17281 gcgaacgtag atgttgtgcc aatcggagaa gaccgttttc ctgtcattac tggaaaaaag
    17341 aaaatgtttg aatttgatga aaatcatttt tatccagcaa aaattgcgat cgatatgtat
    17401 catcattata aggaagatat tgctttattt gcagaaatgg ggttcaagac ttatcggatg
    17461 tccattgctt ggagtcgtat ttttccaatg ggcgatgaaa aagagccaaa tgaatctggg
    17521 ttgaaatttt atgaggatgt ctttaaagaa tgtcaaaagt acgggatcga gccgcttgtg
    17581 acgattacac attttgattg tccgatgcat ttgatcaaag aatatggtgc gtggcgttcc
    17641 agagaactcg ttggttttta tgaaaatctg tgccgagtca tcttcaatcg ctataaagga
    17701 cttgtcaaat attggttgac attcaatgag atcaatatga tccttcatgc accattcatg
    17761 ggcgcagggc tgtattttga agaaggagaa aatgaagaac aaatcaaata tcaagcggca
    17821 catcatgagt tggttgcaag tgccatcgca acgaagatcg ctcatgaagt agatccggag
    17881 aacaaagtag gctgtatgct ggcagcagga gcatattatc catacacttg caatcctgaa
    17941 gatgtttggg cttctagaaa gtcagatcga gaaaattatt tcttcattga tgtccagtca
    18001 cgaggagaat atcccgctta tgcattgaaa gaaatggaac gaaatggcat tcagatcaaa
    18061 atggaacctg gggatgccgc attgctgaaa gaacatactg ttgattttat ctccttttct
    18121 tattattctt ctcgagtttc gactactgac aacgaactct tggaacagac tgcaggaaat
    18181 atctttgctt ctgtcaaaaa tccatatctg gaagcaagtg aatggggttg gcaaattgat
    18241 ccattaggct tgagaataac gatgaatgat atttatgatc gttatcaaaa accactattt
    18301 attgtagaaa acggcttagg tgcagtcgat acgcccgatg agaatggtta tgtggaagat
    18361 gattatcgaa tcgactatct ggcagcacat atccaggcaa tgaaagatgc agtagaatta
    18421 gatggagtcg atctattagg ctatacgact tggggatgta ttgatttagt atcagctggt
    18481 acaggtgaga tgaagaaaag gtacggattc atttatgtcg atcgtgacaa cgaaggaaat
    18541 ggcacattag cccgttcgaa gaagaaatca ttcaactggt ataaaaaagt aattgattca
    18601 aatggagaaa atctttcgaa cgattgatca atgatttata aaagtctatt gtttttcagc
    18661 ggatttttcg agtataataa agctattcga gaaacgcaag cagaacaata gacttttttt
    18721 cgcattggct gtaaagtatg cttacttgat taagtaaagg agaatctaca tatgtatgat
    18781 gtaatcgtta ttggcgcagg gcctgctggg atgactgctg ctttatatgc ttcacgttca
    18841 aacttatccg tattgatgat cgaacaaggc gctcctggcg gccaaatgaa caatacggca
    18901 gaaatcgaaa actatcctgg tttcgattca atcatgggtc ctgatctagc ttataagatg
    18961 tatgaaggtg tttcaagatt tgggacagaa aatgcttatg gaatcgtgca agatatcaag
    19021 gatcacggca gccacaaaga agttatttgt gaagataaaa cttacgaagg aaaaacagtc
    19081 attatcgcaa caggctgtat ccaccgtaaa ttaggcgtac ctggcgagga agaatttgct
    19141 ggacgtggcg tttcttactg tgcagtttgt gatggtgcat ttttccgtaa caaacgtcta
    19201 gtagtgatcg gaggaggaga ctcagcagta gaagaagcca tctatttgac acaatttgct
    19261 tctgaagtag tcatcgtcca ccgtagagat gaattacgtg cacaaaagat catccaagac
    19321 cgtgcatttg cgaatgaaaa aatttccttt atgtgggata cagtcgttga cgaaatcgtt
    19381 ggaaatgaaa tggtagtgac aggtgtgaaa gcacgtaatg tcaaaactgg caatgagttt
    19441 gatttggcag cagacggagt attcatctat gtaggattgg atccattaac tgcaccattt
    19501 agagaagctg ggttgacgaa cgaagccggc tggattccaa cagacaacga aatgaagacg
    19561 aatataccag gcgtttttgc catcggagat gttcgtgaaa aagatttgcg acaaatcact
    19621 actgctgttg gtgatggtgg gattgctgga caacaagtgt ataaatactt ggaatcttta
    19681 gaagaaacaa ctgcataagt ttaaaaagag tgaaagaacg gtttcaattg ttcttttact
    19741 cttttttttg cgtgaaatct actgaatccg atttatgcga atacttgtaa ccgtgcttga
    19801 taaaagaatc ttttcttgat ttaagcgttt tttggtcctc atactttcat atctaataag
    19861 tgaatgctat acttattaag aaccatattt cagaaagagg tgttattttc atgtcttggg
    19921 aacaagtgta tgaacaatgg gtacatgaag aaaatttaga agaaaactta aaaaaacaat
    19981 taaatgatct gggtgaagat cctgaaaaac ttgaagatgc tttttatgca ccgttggaat
    20041 tcggtactgc aggcatgcgg ggaatcttag gacctgggat caatcgaatg aacatctata
    20101 cggtaagaca agcaacagaa ggacttgcac gtttcatgga tacacaaggt gaagaaacaa
    20161 aacgccgagg tgtcgctatc gcttatgact cacgccatca atcaccagaa tttgccatgg
    20221 aagcagccaa aacattagca catcacaata tcccttctta tgtattcgaa agtttacgtc
    20281 caacaccaga gctttctttt gcagtccgtc atttgaagac gtttgcggga atcatggtaa
    20341 ctgcatccca caatccagca gcttacaacg gatataaagt ctacggagaa gatgggggac
    20401 aaatgcctcc tgcagacgca gatgcattga cgaaatatgt ccgtgaagtc agcaatccgt
    20461 taaaagttga agtattatct gacgacgaag ctgaacatag cggattgatc acgatcatcg
    20521 gagaagaagt ggatgccgct tatctagaag aaatcaaagc agtaacgatt gatcatgaat
    20581 tggtggaaac aatgggtaaa gatttgaagc ttgtgtacac accacttcac ggaacaggaa
    20641 aaatgttggg cgaacgtgcg ttgaaacaag ctggattcga acaattcgta ctagttccag
    20701 aacaagctgt cgcagacccg gatttcacta cagtcaaatc accgaatcca gaagaacact
    20761 ctgctttcga gtatgcgatg cgacttggcg agaaagaagg cgctgactta ctgattgcaa
    20821 cggatcctga tgcagaccgt ttaggcgcag ccgttcgttt gccaaatggc tcctatgaag
    20881 tattgacagg aaaccaaatc ggagccctgt ttgctcaata tattttggaa gcacaccaat
    20941 cgcgaggcac tttacctgaa aatgcagcgg tattgaaatc aatcgtttct agcgaattgc
    21001 ctacagcaat tgcggaacac tatggggcta ccatgttcaa tgtattgaca ggattcaaat
    21061 tcattgctga aaaaattcaa caatttgaag aagatcattc ccatactttt atgttcggat
    21121 tcgaagaaag ttacggttat ttagttaaac ctttcgttcg cgacaaagac gcgattcaag
    21181 cattgctctt attagcagaa gtagcagctt actataaaaa acaaggcaaa acattgtatg
    21241 acggcttgca aacgattttt gaaacatatg gctactacgc agaaaaaacg atttctgtga
    21301 caatgagcgg acaagaaggc tctgcaaaaa tctctgcttt gatggaaaaa ttccgtgaag
    21361 aagcaccgac agaatttgcc ggagcaaaag tcatccaaac agaagacttc aaagagttga
    21421 cgagaacaga ccgtgaagga aacgtagaaa aactaacgac accgccatct gacgtattga
    21481 agtatacgct ggaagaaaat ggctggatcg ctatccgtcc ttcaggaact gagccgaaaa
    21541 tcaaatttta tatcggtgta aaaggaaact cttcagaaga cgcagctgaa aaagtagccg
    21601 cttatgaagc gattatcaaa aaaatgacag aagaataaaa aaacttgaga ctgatggaaa
    21661 aagtggtaaa ctttagaagt cagtcttttt tcaagttgga ggtgaatgga ttgccagaca
    21721 cgcaaaaaac aaaagtagag aaagtcagcc aactattcaa aatgttgagt gaccccactc
    21781 gtctcaaaat tctgctgtat ctgaaagacg gggaacaaaa tgtgacagca atcacccaag
    21841 cagtagaaat ggaacaatct gctgtatcgc atcaactgcg tttattaaga gaaaaccatg
    21901 tcgtcaagtc ccatcgtgag ggaaaagcga ttttgtatag tcttgatgat tctcacgtac
    21961 tggatatttt gaaccagacg ctcaaacatg tggaacatca ataacgatag gtgcaaatag
    22021 agacaaactg gactgtatca acgaatcttc ttcgctgaca cagtccagtt tttttaagaa
    22081 aaagacaaga aaaactgtta gtctgtttct tcggtggttt cagttccata ataactatga
    22141 tcttctaggt ctaaagcatt caaaataagt gaagctgttt cttcgataga taaagaagcg
    22201 acattgatta ctacgcagcc caatttttca taaagatcat tcgcaaaatc gagttcagct
    22261 cgtatttttt cgatatcgga ataagcagta tcaggattta atccgtaaga gcgcatccgt
    22321 tctttacgga tattgtttaa aatatctggg ttattcgtca gtcccacgat ttttttagga
    22381 tcgatctccc aaagctgttt gggaatatgt gcttgtggga tcaaaggtag attggcaacc
    22441 tttaaatttt tgttagctaa aaacaagctc aaaggcgttt tggaagttct ggatacgcct
    22501 agcaaaacga catctgcttc tagaaaccca cgaggatctt tcccgtcatc gtattttaca
    22561 gcaaattcca ttgctttgat ccgtttgaaa tagttctcat tcaataaatg aagggcgcca
    22621 ggttgccgaa tgggcttgat accagttaag cgctcgattt ctgatatcgg cggagtcatc
    22681 acatcaaaac taaataattg atgttcttca caaaaagaac gcgtcatctc gatcaattct
    22741 tgattgatca atgtgtgtag gacaagggct ttttctttta gtgcatcttg cagtgcctgc
    22801 atcaatgttt tctcatctgt cacaaatgtt ctgcggaata aattgaactc aacggtagga
    22861 tattgggcca tagtggcttg cgctaatttt gtcgcagttt ctccagcaga gtcagagatg
    22921 acaaaaaaag taatgatttc tgtagaatcg gaagacatgg ataaaacctc acttgcattt
    22981 tttttatgtt tattatacca tactctagaa tgtgtacttc gtaatcattt tgatttggag
    23041 gaataagtca tgaaaaaaca gacattgatt gaacaatcac tagaaacatt gaaaaataac
    23101 ggttttaaat atactaaaaa aagagaagca ttgttaactt atttagtgaa gcgcaatcgc
    23161 tacgtatccg ctaaagaagt ttttgactat atgaatcagg aattcaaagg agtaagttac
    23221 gatacgattt atcgaaatct ccatgatttt gcagaaatcg atttactgga agaaaccgat
    23281 ttaaatggag agatgaagtt tcgttttcat tgctgtcaag gggaaatcgg ccatcaccat
    23341 cactttatct gtacggtgtg cggaacaacg aaagaaatcc atatgtgtcc aatgaattat
    23401 ttcgaagaac agctcggtgg atgtacgatc gaagggcata gattcgagat tttcggaaga
    23461 tgtgaaaatt gtcaataagg atttaaataa aataacattt gataatttta aaaaaaagca
    23521 agatttcctt gacggtcaaa acagcattag atataatatt tacaggacag tcttgttttt
    23581 tgagatatat ttcaataaca attacggtta ctttttaagc tcggagggag ggaattaaca
    23641 tgtcaaaaac agtcgttcgc aaaaacgaat cacttgacga tgctcttcgt cgcttcaaac
    23701 gttccgtgtc aaaagcgggt actttacaag aatctcgtaa acgtgaattc tacgaaaaac
    23761 caagtgtaag acgcaagaaa aaatctgaag cagctagaaa acgcaaaaaa ttctagttct
    23821 gtgatgaatt ggagttggta gtgtgtcact actaagtaga ttaaacgatg acatgaaaac
    23881 agcgatgaaa gcgaaagata aggaatcttt acaagtcatc cgaatgatca agtcatctat
    23941 acaaaacgag cagattaaag aaggtcacga cttgacagaa gaagaagaat taacggtgtt
    24001 gtctcgcgaa atgaaacagc gacgtgattc tttgcatgag tttgaagaag caggacgtga
    24061 cgatttagct gaaaaagtaa aaagtgaaat tgtgatagtc gaaaaataca tgccggaaca
    24121 actttccgac gaagaaattc gacaacttgt tcaagaagca atcacacaaa ctggtgcttc
    24181 atcaatgaaa gaatttggca aagtcatggg tgcgatcatg cctaaagtca aaggaaaagc
    24241 agatggaaac caagtaaatg ccattgtgaa agaactatta caatcttaat tttatcattt
    24301 aaaggctctt cgtcaatgag tgttggtgaa gaaattc
//
LOCUS       DAPBAF010000044        23079 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.044, whole genome shotgun sequence.
ACCESSION   DAPBAF010000044 DAPBAF010000000
VERSION     DAPBAF010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 23079)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23079)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23079
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.044"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(203..658)
                     /locus_tag="RD451_002113"
     CDS             complement(203..658)
                     /locus_tag="RD451_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567347.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            complement(812..2020)
                     /locus_tag="RD451_002114"
     CDS             complement(812..2020)
                     /locus_tag="RD451_002114"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HDT7567348.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            complement(2132..2464)
                     /locus_tag="RD451_002115"
     CDS             complement(2132..2464)
                     /locus_tag="RD451_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HDT7567349.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            2612..3487
                     /locus_tag="RD451_002116"
     CDS             2612..3487
                     /locus_tag="RD451_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDT7567350.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            complement(3569..4150)
                     /locus_tag="RD451_002117"
     CDS             complement(3569..4150)
                     /locus_tag="RD451_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpiB family protein"
                     /protein_id="HDT7567351.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(4156..5415)
                     /locus_tag="RD451_002118"
     CDS             complement(4156..5415)
                     /locus_tag="RD451_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HDT7567352.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            complement(5417..6463)
                     /locus_tag="RD451_002119"
     CDS             complement(5417..6463)
                     /locus_tag="RD451_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567353.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            complement(6698..6973)
                     /locus_tag="RD451_002120"
     CDS             complement(6698..6973)
                     /locus_tag="RD451_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HDT7567354.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(7216..8526)
                     /gene="der"
                     /locus_tag="RD451_002121"
     CDS             complement(7216..8526)
                     /gene="der"
                     /locus_tag="RD451_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HDT7567355.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            complement(8708..9937)
                     /gene="rpsA"
                     /locus_tag="RD451_002122"
     CDS             complement(8708..9937)
                     /gene="rpsA"
                     /locus_tag="RD451_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HDT7567356.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            complement(10072..10752)
                     /locus_tag="RD451_002123"
     CDS             complement(10072..10752)
                     /locus_tag="RD451_002123"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HDT7567357.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(10801..11436)
                     /locus_tag="RD451_002124"
     CDS             complement(10801..11436)
                     /locus_tag="RD451_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HDT7567358.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            complement(11502..12905)
                     /locus_tag="RD451_002125"
     CDS             complement(11502..12905)
                     /locus_tag="RD451_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HDT7567359.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATKQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWETILLNLFKKNMEH"
     gene            complement(12892..13923)
                     /locus_tag="RD451_002126"
     CDS             complement(12892..13923)
                     /locus_tag="RD451_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7567360.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESEVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            13954..14175
                     /locus_tag="RD451_002127"
     CDS             13954..14175
                     /locus_tag="RD451_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HDT7567361.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(14340..15077)
                     /locus_tag="RD451_002128"
     CDS             complement(14340..15077)
                     /locus_tag="RD451_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HDT7567362.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(15230..16570)
                     /locus_tag="RD451_002129"
     CDS             complement(15230..16570)
                     /locus_tag="RD451_002129"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HDT7567363.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            complement(16807..18330)
                     /locus_tag="RD451_002130"
     CDS             complement(16807..18330)
                     /locus_tag="RD451_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HDT7567364.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            complement(18708..19319)
                     /locus_tag="RD451_002131"
     CDS             complement(18708..19319)
                     /locus_tag="RD451_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDT7567365.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     regulatory      complement(19442..19567)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(19649..20365)
                     /locus_tag="RD451_002132"
     CDS             complement(19649..20365)
                     /locus_tag="RD451_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HDT7567366.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     gene            complement(20371..20940)
                     /gene="scpB"
                     /locus_tag="RD451_002133"
     CDS             complement(20371..20940)
                     /gene="scpB"
                     /locus_tag="RD451_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HDT7567367.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            complement(20924..21721)
                     /locus_tag="RD451_002134"
     CDS             complement(20924..21721)
                     /locus_tag="RD451_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HDT7567368.1"
                     /translation="MASKEKEERVNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDI
                     PIATITEQYMNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFGTDDEELWEE
                     DPREELVTQLLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKK
                     IDLIRAMQKILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESP
                     SKSEVVTTFMALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            complement(21691..22062)
                     /locus_tag="RD451_002135"
     CDS             complement(21691..22062)
                     /locus_tag="RD451_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HDT7567369.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            complement(22081..22968)
                     /gene="xerD"
                     /locus_tag="RD451_002136"
     CDS             complement(22081..22968)
                     /gene="xerD"
                     /locus_tag="RD451_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HDT7567370.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
BASE COUNT         6479 a         4932 c         3916 g         7752 t
ORIGIN      
        1 gtaagataac aaaaaatctg agccagaatg aggttcattc tgacccagat ttgattttgt
       61 acaacccatc agtccttatt gacaaagagc ccaaaaatct tgtcacagtc ccttattctg
      121 aataaacggt gtggaagaga cagcctatca gtagtaataa gacacatctc tttcacagcc
      181 tcatttttgc gtaaaaatcg atttattcga aaaattcccc gtatacatct tctacacgtt
      241 gatctggatt gatcacgata tacaagttac ctgttttttc gctgattttt gttgattgat
      301 attgattgtc taatccttct gttcctttat ctagatatgg gaagtacaca agatcaggtg
      361 tgccatttcg gtaaaggatt tccattcgct cgatatcttc gtatttcaat gcgcgattaa
      421 acatgcccat ttccagtccg cctaggttga tatcatgtgt cgcaactgcg tccccttcat
      481 ggaagatttc gattttaaat ccagcacacg gatggatttc aacaaattca ctgccattga
      541 ttcgtccaaa acttgttgtg atttgtttga tccaaagatc gccgatatga cggcggttga
      601 tcgtccaggt ttctccattt ctaaaataaa attttagcgc tgtcatttct ttactcatta
      661 aaaagactcc tttatgatgt aatttattct tgtactacct cagtttagca caaatttatg
      721 taagtggtca catcttatgt tttttcttct aatgacgtat ctgcccactt taagtagcca
      781 acaaagctga gcagatacag tctagtgttt tttaaatcaa tttttctttc gataaaaaat
      841 ccaaaacctg ttttttatca ttttttattc tttgttctac gacggctttt tcagctaatt
      901 gcaaagcttc actaacccac ttaccaggtt tttttccagt ttcttctagc aagattttac
      961 catctactgc taattcgctt aatgacttga taggtaaacg atcataggat tctcctacgg
     1021 catccatctg aggtgtttcg tcaaaataga tcatcaattc ttctacttgc agtgcatgtt
     1081 ttttgcctaa gaagtacaat tcgaatggtt ccaaagctcc agtttctcgt tgtcgtagtc
     1141 cttggacaag tgcttgaacg tctttaatca tttggttaga acacttccac gatttcaaaa
     1201 aggaacgaat ctcattttct tttagatcca gttggctgat caataatgcc catgcttggc
     1261 tctcttcttt caatgggacg gatggtaatt cagcaaaacg taaaagtgct tcgccttctt
     1321 ctttcaaacc gggacagcaa atgtagcact ctgtttcaat aaatgcatgg attcccgcgg
     1381 cccgttcatt tcccaagagc atcttgatga attccacatt tatacgttct acagatattt
     1441 tacctaatag ctcgtggttt tctttgatgg cgtagaaggt ttcttcctct aatttgaacc
     1501 ctagttgact gacaaaacgc aacccgcgca tcattcgtaa ggcatcttca tggaaccgct
     1561 catgaggatt gcctacagct cgcaagatct gttcttctag atcttgcaga ccatcgaaca
     1621 aatcgatgat ttctccatct tctttcaaag caaacgcatt gatcgtaaaa tctcttcttt
     1681 tcaaatcttc tgccaacgaa cgaacgaatt cgacatgatc tggtctacgg tagtcctgat
     1741 aagttgattc cgtccgaaat gtggtgatct catattgttc atcattttct aataccaaca
     1801 cagttccatg ttcgatccca atatctatcg tttttggaaa aagctgtttg atttcttctg
     1861 gaaatgcgct tgttgcgata tccacatcat ggattggctg gttcagcaag atatcacgaa
     1921 cacttccacc tacaaaataa gcttcatatc ctgcattctc taattttttc agaactggaa
     1981 ttgccttttg gtattccaga ggtaattgtt ttaatttcat ttttccaacc tttcctgcgt
     2041 gtttcttgtc ctgagataaa gactcagttg catggtgact gtttgacaag tccgtttcag
     2101 agtcttcaag gccaggacca cttcatcttg tttactcgtc cttacgctca aagcgattat
     2161 ggtctctttg attgaatttt tccatgtttt tttcaaaaac ttcagttaag tcgatattca
     2221 atgaattagc catgatcatc gtaacgaata aaacatcacc aagttcttct gctaccgagt
     2281 taactggttc agaagccttt ttgctttttt ctccataagt gtggttgact tctcttgcca
     2341 attcacctac ttcttcagtt aatcgagcca tctgagctaa tggagagaaa taccccacct
     2401 tgaattgctg gatatattca tccacttcct gctgcatact gtataaagaa cgctttttat
     2461 ccatcttttt ccctccaaaa ctatcttacc aaaactttaa cgcaaatcct agataagagc
     2521 aattgagaaa atcgaatttc catgctacat ttaggaagga atttctaaat ggaaattctg
     2581 tgaaaataca taattgaaag ctggaattca tatggtcaaa cgaaaaacag taaaagaagt
     2641 tctttttatc attataggaa caagtattta tgcatttggt cttgtttact tgaacatcgc
     2701 taatcattta gcagaagggg gagtctcagg gatcaccttg atcttaagag ctttatttgg
     2761 tattgatcca gcttatacga ctttattaat caacatccca ttgattttac taggaggaaa
     2821 gatcctcggt aaacgttcct tggcctatac tgttctaggt acactttctt tgtcattctt
     2881 tttatggatc tggcaaaggg ttccactaga aatcaattta cagcatgatc tactgatcgt
     2941 ttctctactt gcgggtttag ttgcaggtgt aggaagcggg atcgtctacc gcatgggtgg
     3001 aacaacaggc ggcagtgata ttatcgctcg gattttagaa caaaattacg gcatcactat
     3061 ggggcgttcc ctattggcat ttgatatcat cgtcttactt gcttcattaa cctatatcga
     3121 cttgaaacgt atgatgtata cgttgattgt ttcgtatgtt ttcagtcgtg tgattgattc
     3181 gatcttagat ggcggatatt ctgcaaaagg tctacttgtc gtctccaaca aaagcgaaga
     3241 gattgcacca ctactgatga ccggtctgca aagaggtgtg actttccttt ctggagaagg
     3301 cgcattctct ggtaattcaa aaaaaatcat ctatatggtc gttagctcta gtgaattaac
     3361 tgaagctaag aggatcgtcc acgagattga cgaaaaagct ttcctttcaa tcatcaatgt
     3421 gcatgaagtg gaagggcaag gctttactta tttgaagcca cagacaagat tactgaaaaa
     3481 actataagaa aaaagacaaa gataggctat gaggaaagat tccacatcca gctgaccttt
     3541 gtctttttta gtactatact atttttaact aattgttatg ttcacttacc cggttacttt
     3601 tcttttgtgt ctgcaaaagg atctttcggt taacttcatc agataatttc aaaaaagcat
     3661 ccctatctcc atcttctagt gcttgatcga tttgagcata aagcattttt agttttgcct
     3721 cttcttcttt ttcttgaaaa tatcgttcaa ttaattcagt atcttcttca ctgactgaag
     3781 aatcccaaga agaaaatgga ttgtcttcta agatagatag atattctctt gtctgccaag
     3841 cattttcgaa tatacattcc acatataaag gctttttcca attcaaacgg atttcatgaa
     3901 aaatctggtc tgtgtccgta aattcttttc cctgcaaaaa caatttcatg ggttcccctt
     3961 caacagatag atcactgatc tgcagtcctc gatccgcaaa attcgcccct tcaacaaagt
     4021 ggacattgct taaaatcgct tcatgattgg caagataatt caagatccaa aaaacttctc
     4081 ttcggctaaa agatacatga ttgaccatcc acgttaaaaa attcttcttt tcccgtacat
     4141 caattagcat ttttctcacc tctctgttag gtcatctaat aatgacagtg cctccatatc
     4201 tcctggttca agtgttaaat aataagtcaa taattcttgc gctcttttca gctgcccttc
     4261 ttctcttaag aaaaaggcat actctttcaa gaaatctggt tcatgtgata gttcatgata
     4321 agcctgttca tagtgtacag ctgcaacggt aaagtcttct aattcattat aagcatgggc
     4381 taggttccat tctgcataag gattagcagt ttcttccatc tgattgatca cttgtatcac
     4441 atcttcatat ctttcatcat ccaagtaaag attacttaaa gtaagtaatg tttcatcttg
     4501 tttgtctcct acttctaaag ctttcagtaa aagttcttct gctcgctgtc tatcatgcag
     4561 acggaaagca ttttccgagg ccaggtgata aagttcgact tggtaaggat tttctttgat
     4621 tccttcttct aacactgttt gtgcttcttc aatcatttct tcttcttgaa gagcttgtcc
     4681 tagatataga tataacgatt gataatgcgg attaacttct cgaagttctt ccagatagtt
     4741 gattgcctgc tgattttctt tcaattgaag attcgtaaaa gctagctgga acagtcgatc
     4801 atctgtcctt tcttctttca gtgcttcttc taaaggtacg atagctgctt cgaattctcc
     4861 ttgcatactt aaggattgtc ctaaacgttc ctgcatcgag attcctgaaa tttcatttat
     4921 cccgcttgcc aacaatgttt cataaaccac tgctgcctct ttgaaacgat caactgaaaa
     4981 atacaattca gctagcgcaa actggatcaa tggttcatca ggaagcaacc cagctgcttc
     5041 tttcaatttt gcttcactca cttcagggat tccgataact tggtacaaat cagctatcgc
     5101 caataagctt tgcggatagt aatcactttg cttatccact ttttccaggt attcaaaagc
     5161 taagtcgatc tcattatctt cgattgcaat ttctgctaac gggatgttca gtccgtcatt
     5221 ttctgggtat tggttgatca gttgttcaaa aatctgtttt gcttcgatca aaaagccaat
     5281 agccagcaat tcttcgccta gttcagctaa tatatctgct gggtcttctt ttaatgcttt
     5341 ttctaaaaag atttgtgctt gtgacaagtc ttcatctgat aaagcttgca acattttttc
     5401 gctatttgta ttcatttcaa ttccctctta tctcactgac gatttgttga aataccgtca
     5461 ttgttctcaa taattctttt tcgtttggat gttggtatcc gtctattata cctatttttt
     5521 ctaaaacaag tatttttttg cttttttctg ccaaaaaaag aactttttcc aaatactcca
     5581 tctttgaaat ctgttccagc cagtggattg gatagccaag caagtccagc cacacaaaaa
     5641 agttttttag ttggaaatca aaaggatatg cttggagatt ccacacgaaa tgaaacatca
     5701 ttcctaaaaa ttttttcata ctagcagaaa gtagatggcc attttcggtc agataaaaag
     5761 cttgttcaaa cagtttacca taatttgaca ggttttctgc ctctaattga taaaaataga
     5821 tcatttcttc gatcatcccg gcaaacggcc gagtcgttaa ttgcttttta tttggatagt
     5881 ttttatacag attttgcaaa aaacgatgat cacaaatcat tccgcaacag ataaaagtca
     5941 aaaagtcaat ctgctttccg tccacctgcc gctcgctgat tgtttgatca taaacgatgc
     6001 gttctggcag attgatggtt tgcagcacta cacgatttgg tagctgcaaa atcgtccgct
     6061 gcggtgttaa tgctcggctt agagaacgga tcgatacagg gatcatccat agtgatgaat
     6121 caagggttgt atgtttttga aaaaaacctg ccagatccat gatcccttca tttccaaatc
     6181 cgatgataaa catggattga ttttcgggat agcgtttgac gaaatcaagc aggttcttta
     6241 attctgttaa atgattgcat tgagtgttgg cacaaatata ccagtcattg tttgcttgat
     6301 ttgcaaataa cgggttgatc ttatctgcaa acaaatcata atagcgctga ttcgttaaaa
     6361 ataagattgg ctgatcaatg gaaagttctc ttagctgact gactagcgtt tctccgtaaa
     6421 acactttcgt caacgcatct tctacttgat aatcaagttc catacgcatc cctcctcttc
     6481 ttatttttat tttaccatta gtaagcaaat tctagaaaag ataagagcaa agctcacctc
     6541 ataacttgga aataaataaa aattaaataa aatacatgtg ttttctatgt atgacatacg
     6601 gattcggaat ctctgtctct tatttattcc ttttctgcta ggaaataaaa agaaaagcac
     6661 ttgtagccct agagccacaa gcgctttttc aactgtctta tttaacagcg tcttttaatg
     6721 ctttacctgg tttgaatgca ggtactttgc tagctggaat ttcgatttct tcaccagttt
     6781 gtgggttacg acctttgcga gctgcgcgtt cgcgaacttc aaagttacca aaaccgatta
     6841 attgaacttt ttcgccgtta gctaaagcat cttgaatagt tgaaaataca gcatctactg
     6901 ctgcagttgc atctttttta gttaaatcag tagctgaagc aactttttcg attaattctg
     6961 ctttgtttgc catggataga ttcacctcct ccacaagaga tatgatagaa atatcattta
     7021 gttaaaactt tctgagtggt ccagaagttt aaaaagaaat attgattaac ttcaatattc
     7081 tgttatcacg atatcatatg aaccgcttaa tagcaaggtt tttaccaatt ttcacatgct
     7141 ttttttagtc atagaaacgt aacaaacgaa actgtctttt tcttttgaaa aaaaaacgtc
     7201 gatatggtaa aatgcctatt ttctcctacg agggataatt cggatggacg tcccttcaaa
     7261 agtaaatgct tttctgattt gattttctaa gaaacgttca taagaaaaat gcatcaattc
     7321 ctcttcattg acaaaaacga caaatgtagg tggtttgaca gcgacttgtg tagcataaaa
     7381 aatcttcagg cgttttcctt tatctgttgg tgttggattg attgctacag catccataat
     7441 gatatcattc aacacagccg aagagatacg aagattctgg ttcatactta cttgttcgat
     7501 catttcaggc agacgttcca accgttgttt agtcactgca gaaacaaaaa cgattggagc
     7561 gtaatcaaga taccggaatt catcacgaat ctcttgttcg aaatcacgca ttgtattggt
     7621 ttctttcttt acaagatccc atttattcac gacgataata attccacgac cagcttcatg
     7681 ggcgtaaccc gctactcgct tgtcttgttc ccgaatccct tcttcagcat tcagtaccat
     7741 caaaacgata tcagaacggt caatggcacg cattgcacgc atcacgctgt atttttcagt
     7801 attttcgtat acttttccgc gtttacgcat accagctgta tctatcatta agaatttctg
     7861 accactttca gaaacgaagt gggtgtcgat tgcgtctcgg gtcgttcctt caatatccga
     7921 aacaattaca cgttcttctc ctaaaatcgc attgatcaaa gaggatttac caacatttgg
     7981 gcgaccaatc aaactaaact taatcgtgtc gtcgtcctct tcttcagtct cttcagagaa
     8041 atacttcact gcttcatcta aaatatcacc aatccctagt ccatggcttc ctgaaacagg
     8101 ataaggatcg cctagcccta aggaataaaa ttcatagata tcgtttctca tttctggatt
     8161 atctacttta ttgactgcta aaatcactgg tttattactt ctgtataaaa ttttcgcaac
     8221 catctcatct gcgtctgtca cgccttcgcg tccgctgact acacaaatga ttacatctgc
     8281 ttcttcaatc gcgatttctg cttgatgctt gatctgatcc ataaaaggtt catcgccaag
     8341 atcaattccg cctgtgtcga tcacgctgaa ttctcgacct aaccattcac cttttgcata
     8401 aatacgatca cgagttactc caggagtatc ttcgacaatc gagatacgct caccagcgat
     8461 gcggttaaaa atcgtagact taccgacgtt cgggcggcca acgattgcaa ttgttggatt
     8521 tgccatatta tttcctcctc acaagtttcc aatctcactt agtttaacga atgcattgcc
     8581 aactttcaag catagattgt caattaaacg aagtattttt attccttatt gaaatactaa
     8641 tcgcttttca aaagaaaaac tgagacaaaa gcagctgctt tcatctcagt cacagataca
     8701 aaatcaatta tttttcagaa tcatcggttg ctttttcttc tacttcttct ttcaacgcat
     8761 cacctaaaat gtctcccata gtaaatccag tattttcttc tggtaattca taagactcaa
     8821 cattttttgg ttcttcttct gaagctggtt tttcttctaa agctttgata ctcaatgcaa
     8881 tacgatgttc ttctggatgg atctctaata ctttcacttt cacttcgtca ccttcatgaa
     8941 gcacttcatg tggtgtcgca atatgtttat gtgaaatttg agagatatgg actagccctt
     9001 ctactccagg gaacacttca acaaaggcac cgaagcttgt caaacgttta actgttccgt
     9061 ctaatactgt gccaactgga gcttttgtat cgatttctga ccaaggtcca ggctgtgtgt
     9121 ctttgattga caaggaaaca cgttcttgtt caggattgat agacaacact ttgacattta
     9181 catcatcatt gacagccaat acatcacttg gttttgctac atgactatgt gaaatctctg
     9241 agacatggac tagaccgtca attccgccta ggtcgacaaa tgcgccaaaa tcagtaagac
     9301 gtgcaacacg tccactgaga acatctccct catggatagt tgaaagaatt tcttttttct
     9361 tttcttctct ttcgttttcc actaccgctt tatgcgataa gatcaaacga ttttctgatg
     9421 gttcgatttc gatgatttta aagctcaatg ttttgccttt atagtctgaa aagtctgcaa
     9481 caaaatgatc ttccaccatt gatgcaggga caaaaccacg tacaccgacg tcaacgacta
     9541 aaccgccttt gacaacattt gtaacaggtg cttcgatgac cttgccctct tggaaatctc
     9601 tttcgatatc ttcccaaact tttttagcat ctaaacggcg ttttgaaagt aggtagctgc
     9661 cgttttcttt atctttgccg atcgtactga taacgactaa atctaataca tcaccgactt
     9721 ttactacttc gctgatatct tctaccggca aagttgataa ttcttttgcc ggaacgactc
     9781 cttcaactcc agccccttcg attccgacaa tcacttgttt gtcttcaatg actaaaactt
     9841 cgcccttaac aacatcgcca acttttactt cttgtacgct tttcattgcg tcttccattg
     9901 actggttgtt ctcttgattt tgatcaaatt ctgtcataac acttgtcctc ctaaccaaca
     9961 ttctgccgta agtacggtac tgtttttagt ttaattgatt attcaaaaaa aataaagcga
    10021 tttcgttcgt tttccttgaa aaaacaattg tttttcattt tttttcttaa tttaaaaaag
    10081 aagataacct tttttcaaaa caacagcttt tattgctgca acgacttctg gaatcgattt
    10141 gccagtcgta tcgatacgaa cagcatcctc tgcttgcttc agcggagaga cgtcccttgt
    10201 tgaatcataa tggtctcttt cctgtatctc tttcgtcagt gtttcaagat cagtcggaat
    10261 tcctttttct tggttctctt tgaaacgtct ttctgcacgc tcacttacgc ttgctactaa
    10321 aaagattttc acttctgcat tcggtaatac agctgtcccg atgtctcttc cgtccatgac
    10381 aacgccaccg cgttccccta tttttcgttg gacagcaact aattcttctc tgacttttcc
    10441 atgtgcagag acttcagaaa cagcttttgt gacatctggt tgacggattt ctaaagtcac
    10501 atcttttgat gctatgaata catgctgtcc atcttcttgt tgcgaaaaag agataggata
    10561 ctttttgatc agcgaaacta gcccttcttc atctgaaaaa gatacattgt tcgtaatagc
    10621 taaataagtt actgcgcgat acatggcacc ggtatctgta taaatataat tcaattcttt
    10681 tgctaatatc ttggcaacgg tacttttccc agatgaagca ggcccgtcga ttgcaatact
    10741 gatttgtgtc atgatataac tcctttttct cagaaaaaaa gccgcaaagc gcggctatta
    10801 ttatttaatt cttaattctt gaccagggta aagcataaag ttgtttggat ctaagccatt
    10861 caattcaaac aattgatcag tggtgatccc tgcacgctca gccacttgtt ttggaccttc
    10921 gcctgcttga acagtcgttg ttgaaccggc tgcagctgat gaagaaggtg ttgtttctgc
    10981 tgcattgctg cttgaatccc ctgcttgata agttgcctca cttgaggaag tcggtgttgt
    11041 ctctgctgca atactgcttt ctgacgttac acctgtatct tgagacacag tagattcttc
    11101 cgcgattgta ctagattcta ctgttgaagt ctcagttgac tcctcttttg ttgtacttgt
    11161 agaactttct actactgatg tcgaagtttc agaagaagtt gctgctgttg cattgttgct
    11221 tgatccattt ctgatccaga aataagcacc tgctggaata gcgatacata agaccagtaa
    11281 aatcaaaaat agcgaaagaa ataatgtatt tcctttcttt tgttgtctct gagaacttct
    11341 tgatgaaact tcatcatctg tatcgtagat tggttgttcc catggttctt gtgtttcgtt
    11401 attttctgta gattgatgtc tatcttttct gctcactgtt ttacctccta aactctatcg
    11461 tgtgtattat accataggaa aaagtgtctt gtcctaaaaa atcaatgttc catgtttttt
    11521 ttaaataaat ttagtaaaat cgtttcccaa tgaagttgtt cagtcttaga aaaaagcttc
    11581 ctctttggca gaagttctgc ttttgctcca tcaatatcac aacaattctg cggcttttcg
    11641 gagagttttt cgccaaaata agctaagatg aattttctgc ggcagttttc ttcattaata
    11701 tagcgaagca tctgctgcag gcggaattct ttttcttttt cctgacgttt gagccgttcc
    11761 acccaatttt ctggtttttc agactgctgg atcagctcca tccatttttt ttgcagctca
    11821 tcaaagggag cttgctttgt ggcatattcc aaataaagct caaaactttg tcgctgttct
    11881 ctagaaagtt gattaaagaa ataatggata cgttcatccc cactttgata aaaaagaatt
    11941 gctgcacttt cttcctgatc tctgcctgct cgaccgattt cttgtacata gttttctaga
    12001 ctgtctggca aatcataatg gaccacataa cggatatcag atttatcgat ccccatacca
    12061 aatgcattcg tagcaatgag aaactgcagc tgatttttta caaactgctg ttgaagttgt
    12121 cttctttgag ctgcatcaag accaccgtga tagtatccaa ctgtaaaacg ttccctgaat
    12181 aaatgataca atcgttcgac ttcttttttt gttgcacaat aaatgattgc cgctccttgt
    12241 gctctttcca tgaagtgttc aagttcttgt tctttttgct gcgttttccg aacaaaaagc
    12301 gagatatttt gccgattgac tgattgtctg atctcttttg gtggtcgatc aaatagtaca
    12361 tgacgtatat ctcttgctac taaatctgtt gctgtcgccg ttagtgccag tgtgaccggg
    12421 tttcctaaaa gctttcggat ttttcctaac tgttgatatt ctggacggaa atcaactccc
    12481 cattgagaca cgcaatgagc ctcatctact acatataacg caatattttg ttttttcaga
    12541 tgctctaaaa gagaaggatt agtcaacatt tcgggactca aaaacaaaaa tttatattgc
    12601 gatagatgac ggaggacgta tcttctttca gattgcgaaa gtaaactatt gaaagcagct
    12661 actcgtttct cccctcgttt ttgtaattgc gtcacttgat cttccattag agaaagcagc
    12721 ggtgacacga tgatgaccag accttccatt aaataccccg tcaattgata gcaaaggctt
    12781 tttcccgttc ctgtaggcaa aatagcgaga gtatcttctc catcaagcaa cgcctgaata
    12841 atttcttctt ggccgggacg aaatgaatca aatccaaaat atttttttaa ttcatttatt
    12901 aacattctgt atcgcttcct ttctcaatag atagatttga tacaaacgaa attctccata
    12961 atctaattgt ccatctacat tccattcgct aaagcgccac tctcgcacgg aatccttatt
    13021 tggttccaaa cgttcgattg tttctgcaga gagaatccac tcgtatggaa aatcatcaaa
    13081 aaacaaggcc cactcaataa gatgatctgt tactgttcct ctttttaaat gacggattgc
    13141 catgatctgg tcaattgtct gaccattcat aaacatctgc ttggtgatca tcatgctttg
    13201 attgaaattt tgctgtaata atgaatcgat caaagcgtgc caaagcgaat ctggccgttt
    13261 ttcgatttgt gctaacaaaa ggtggataca tctgctttgt tgcagataaa cctctgactc
    13321 atcattgttt tttgccagct gataaggaag cagccctgtt cgctcatttc cagataattg
    13381 gttagctaaa aaatctgctg cttcttctgg tatctccgaa aacagctgca ccaaactctc
    13441 atacgcagta tcaattaaaa tttcacgtgg caattggctt tcactaagcc atttttttag
    13501 ttggaaagta taaaaaggac ttgtctctgc tggaagatag tcttgaatac ccgttgccag
    13561 attagaaatt acttgaacag caaatttaat gagccgccaa ctagtttccc ctgttctgcc
    13621 atagcggtca aaacgcaaac cagtatgttc tatttgatgt tcggacaaca tatcagcccc
    13681 tgcaggcgtt agctttgctt cattttcatt tatttcgatc caaccttgct gcgcaatttt
    13741 ttgcaaaatt tgataaaact tatcctgctt caattctgga aaactgttat ggataaacaa
    13801 aagttcgtgg gtaaatccat aaataagtac tgaagtcgtt cgttttccca caaggagttg
    13861 gtaaagagaa ctaatccgca gcttgtgtcc tgatgaaaat agcgataaaa taaaaacaat
    13921 catattattc tccttaagtt aggatggtta gaaatgtcac tactatgtaa acttgtacct
    13981 gaacgctgta ttgcatgcgg tctttgtcaa atcgaagcgc cagatatttt cgattatgat
    14041 gaagaaggaa tcgttttatt tgcccaagaa ccagaggctc atcaacagtt cgtgatgccg
    14101 gaagaagaaa catatgtaaa aaaagcgtat caaaaatgtc cagttcgagc gattttatta
    14161 gaaaataaaa tataaatata aacgaaactt taaaaacgta cactaagttc tctaaacttg
    14221 aaaataagcc gggatctgtt tctcttgttc cgtgaaatcc cgacttattt tgaaagattc
    14281 atttgctatc tatagttaat tgactagttt tttcacggac cctataggac ccatttatat
    14341 tatttcaact ttttcagcca gttttccaat gtattgacga tcacagtttg ctggtctgcg
    14401 ttagaaattt ctgcctctcc atctcctttt tgctcaccat agctgccaaa acctccatga
    14461 tttccgccat tgattgatac atactctgtt ctttccggta aatactgctt agcttcttga
    14521 taagcttcct gattcaatac tttatctttt gtcgccgtga tcgataaaac aggaacagct
    14581 gattctgtca atgttccttt tttgtcggga taacttgcca tgaagaatac cccttttaaa
    14641 tgtttgtctg aatgattctt attgacataa cgacttgcca ttacgccacc taatgaatgg
    14701 ccaccgatca cataatcgga atttggaaaa tcttctttga ccttatccgc tttgtttccg
    14761 cccatcactg ctagatcaag tggcattttg acaatagcga ctgaaaagcc gttttttgct
    14821 aaatcttgcg cccaaatact ataactttct ggctctacga gagcaccagg ataaaaaata
    14881 agtaatggag actttccatg attctttttc tctccttcaa aaaataagta atcttctttg
    14941 ttttttcctt cttttaccaa cacttgcgct tctgacgatg gttcgtacgt attttgctgt
    15001 atatagtaat aaccggctcc accgagtaat cctaaaatga tgactaagcc aattagtatt
    15061 cgtctaaata ttttcacttt ctcccacctt ttctatctga gtgacccctt tttcttaatc
    15121 aagtatgatt ataccttaaa aaaataagag agaaatgcaa actttccagc atcaaataaa
    15181 aaaagacgga atatccattt gaatatccgc cctttttgta tgtttatttt tatttagcac
    15241 ataaacgata cacagcttct gcataaattt ccattgcttt atacatacta cttaattccc
    15301 atcgttcatt cgcctggtgc ataaagtcag gagtatcagg gaacatcgca ccgaatgcca
    15361 cacactggtt catcgtacga gcaaaagtag cgccgcctga tacaaacggt tcagtcatgt
    15421 ctccagtaat atcgcgatat gtccccaata gatttttcac taactcactg tctagtggca
    15481 cgtataatga atcaaggaag tcaaattctt cataagtcaa cccatatttt tctgctgttt
    15541 tagttaattt agctactaaa tcatctttct tgaatgtaac agggattctc atatctacac
    15601 cgatttttgt ttgttctggt gtgatttcca aacttgcaaa gttcatcgtt agctcgccgg
    15661 attgttcatc ttctgttttg cccacgacag cttcaccagt tgcattttct tgaactaatt
    15721 ttcctaagaa attgattggg ccaaaatcaa atacttctga aagagcaatt gccagacgag
    15781 aaatagcatt cactccttgt gctgcatctt tcgcgtggat acttttacca agaacgacga
    15841 tgccttcacc ttgttcttcg aaatcgaatt cgtgtttttt caatgcttct tttacttcag
    15901 aaagcttttc tccagagtaa ggagctgcat caggaacaac attcaacgct cctccagctt
    15961 ttacagaaaa ctcgttcgtt cctggtcctg tcaagtaagc ttgcaataag cctttttctg
    16021 cataaattaa aggaaattca gcatctggcg caaatccttg cgtaattcct tcttcttttt
    16081 cgttatattt ttctaaacaa cgccataaat tttcttcatc tgtaccaaag ataaaacgaa
    16141 tacgtgtctt gaattccacg ccagcatcaa tcaaagcttt gacggcatac attgccgcaa
    16201 tagaaggacc tttgtcatct tgggatccgc gaccaactaa ccagccgtct tttatagttg
    16261 gatcgaatgg ttttgtttcc caattatttt cgtcccctgc tggaacaacg tccatatgac
    16321 acaagatacc gaataattca tctccagagc caatctctga ataaccgtaa tagccttctg
    16381 gatctttaaa tgttctaaat cctagctttt cactgatttc caatacttta tccaaagctt
    16441 caatcacttt tttaccgaag ggatgtcctt gtcctgaatc tgcttcatct agtacggaag
    16501 gaattcggat caattcgctc aatgattcta atgcttgttc atgatgttgt tctgtcacaa
    16561 attttttcat gatattatcc tcctaatatg ttaaaaaggg tcatgtcaaa ttcctccgac
    16621 acaacctctt cttctcaaat aatgacgttt taagcctgct ccatcagcaa gcagaatgtt
    16681 cttaacaaat gatgaaagaa aaaacactca ctgaatggag ctattgactt gtccacgtgc
    16741 ttatcgatag ccgtttatcg gtttcttcat tcttatgata gaccttgtac ctgtatttgt
    16801 ctaggtttag aacattgctg ctacacctag gatcacacag atggctacaa ataatatcgc
    16861 aattaattta ccggtaaatt tccaccacac tgaaacatcg aaacgagcaa ttgctacagc
    16921 acccattacg atagcagatg ttggtgtaat taagtttact aaaccagatg cagattgata
    16981 agcagtgatt actaaatcct taccgacgcc ggcaaattca cccataggtc ccatgattcc
    17041 cattgttgca gcagctaagc cggaagttga aggaatcaag aatgacatag ggatatagaa
    17101 aataaatgta ataatgatga atacacttga agataatgaa cttaatcctt gttcgcccca
    17161 atgtaagatg gtgtctgtga ttaatccatt gttcataacc acttggatac cacgagcaac
    17221 agctactacg attgctacac cgatcaaatc agaagcacca gctaaaaatt cagagacaaa
    17281 ttcagactct ttcatgccat aagtgattgc tactacgatg gacattacta agaataacat
    17341 agtaatttct gggaagtacc agtcacctaa tggaagcatg cttttaccta gaaccgtacc
    17401 tagtaccgga aggtttgtta accagtttgt caatgattca aaaatcgtga aattcgcatt
    17461 caaggttgtc caaggaatca aactgatgat catgatacca aaagtaataa agaacaatac
    17521 attaacatgt ttttgttttt tcgtgattac ttcttgacga ccgattgctt caatatcgaa
    17581 atgcttcata tcttctttac gttggttgta tactaatgat tttgttggat ctttttcgat
    17641 ctttgatgca taacgataca catatacaat agaaatagct aacaaaataa cgaacatcaa
    17701 gaatcgaaga ccaatacctt cacccatcga aatcccaaca gcttgtgaag ctacgcctgt
    17761 tgcaaaagga tttaccgttg aagctagaca gcctacttga gaccctacta atacgattgc
    17821 tacagctact actgtatcaa agcctacagc catcatgact gggatcagta aagcatagaa
    17881 tggaatcgtt tcttctgcca ttccgtaagt agagccgcct aatgcaaata acagcatcaa
    17941 tactggaata agcatttttt cttttccttt gaatttcttc acaactgaag caatcccggc
    18001 atctagtgcc cctgttttgt tgataatacc taaaaatcca ccaacaacca aaatgaagaa
    18061 agagattggg attgcagcag gtgtttcttt agttagctcc cccgctggta cacctagcat
    18121 cccattgatt ggcgccatga aaatatccca cagcccttga ggattttgtt gtactcgttc
    18181 atatgatcca gcgacgatgt tgcctgcatc gtctacacta tagtgcccag ctggtataaa
    18241 ccaagtaagt acagcgatta ctgcaataat aataaataag accgtatacg ctgaaggcat
    18301 ttgaaatttt ttcttttttg tttgttccat cttcttcttc ctttcttttc cgttagagac
    18361 aacaattttg gctctaatgt tattttatca aaaagagtat cagaacaaaa ataataacac
    18421 gcattttgta aaacttttgt tcaaaaagtt cgtttttccc tattccctcc tcttttttca
    18481 ggtttttaaa gctttcttct ttttcattgt agcgtttcct tttttttata aacaaacatt
    18541 ttcgtctttt aaaaggagaa gaatttcaca tttgcaaaga attgattgat ttttatgcat
    18601 aaatcaaaaa aatactcaaa acaaacaaat aaaacgttta cattattgca tgtcttgtat
    18661 ttttttccaa aaaaaaagac caagaaattt cttgatcttt ttgatattta tttgactgct
    18721 gtatgacgtt gttcgaactg atgttgtttt cgacttaacc atggaagaag ttgcgcatgc
    18781 agcactaaaa agacagcact cacgatgaat cctttgatca agttgaaagg aacgatccca
    18841 atcagtacat agtttgctaa agacatgccc agcatctgtg ttgcgttcag ccctaaaaac
    18901 attaagtaaa gaggcgtaat aacgaaataa tttgcgatac tcataaaaat agttagagcg
    18961 atggttcctg taatgacacc taaaaatttg tttcttcctt tatgctgttt ctttacacta
    19021 aagaaataat aaatcgggaa tgtaaagatc gttgttgata agaaactagc agtgtctcct
    19081 accaaattat ccggagaaaa acctgtagtc agcagatgta atactgaacg caagaacgct
    19141 gttgcaactc cggccgctgg accgaataag aacatgctga tcaataccga gatatcacta
    19201 aaatcgatct tcaaaaaact aaaagccggc atgatcggaa aagcaaaata ctgtaaaact
    19261 aatgcgatcg cagcaaacat cgctactgca accattttct gtacacgggt gttcttcatt
    19321 tgaaatcctc ctgttaggac tcctcttcag cgaacttttt gacgtttctc tccaaatgaa
    19381 aaaactctat tttccaggga aaatagagtt agagttattt gatcaagcgt cgtcaaataa
    19441 gctctatctt ctttatccag actatactgt cggtatcgga atttcaccga ttcagctatt
    19501 tttttgcaaa ataggtcgtg gactataacc accggtcggg aatttcaccc tgcccctgaa
    19561 gacgaacctt atataatttt tgtttacata ttcattatac atatctattc aaaaaacgca
    19621 acatctaaca cttataaaaa gtaagtgttc attttgagtg gttcagcaaa ctgctgactt
    19681 cttttttgtt cagttcacgg taatccccag gacgtaggcc ttgtaaagtc agatctccgt
    19741 atttttcacg ttttagtttt tgcacaggaa gaccaactgc ttgaagcata tttttcactt
    19801 gatgattacg tccttcgtgg atcgtcaatt ccacgatact gtggtttgtc ttaggatcca
    19861 ctgataaaat ttggaattta gctggagatg tttttcgtcc ttcgatcttt attccttttg
    19921 tcaaaggtgc aagcatcgat tttgtagcga tcccttttac ctttgcaacg taaactttat
    19981 ccacttcatg ttttggatgt gtcaggcgct gagcaaaatc tccatcattt gtcagtagca
    20041 agatccccga agtatcgtaa tccagtcgac ctacaggata gatacgttct tttaccatcg
    20101 gcaaaagatc cgtaacaact tttcttcctt tgtcatctgc aacagcagaa ataactcctt
    20161 taggtttgta caataaatag taaccgtatt cttcttgata aattgggact tcatccactt
    20221 ccacagtgtc atgtttccca acttttatcc ctaattccct tacaacttgt ccgtttactt
    20281 ttacacgtcc tgcaaggatg aattcttctg cttttcgacg agaagtgatg ccagcgtggg
    20341 caattacttt ctgcaatctc tccattacaa ttattctcct ttattcattc catcaaagaa
    20401 tagatctggt gacacgtctt cttcaagtga aatttccatt tcttgtgtat caggcagttc
    20461 ttctaatgat ttcaaaccaa aataatctaa gaagtagcca gttgttccat ataatatcgg
    20521 ccgacctggt ccttctactc tacctttttc ttcaatcagt ttatgggcag ctagacgctg
    20581 taccgctcct gaaacctgaa ctcctcgaat ctgctcgatt tcagctcttg tgattggctg
    20641 tttataagcg atgattgcta aggtttcgac ggcggcttga gataatgtgt ttgatgtccc
    20701 ttgcgcatat cgcttaagta agggagccag ctctttttta gtcgttaata cataatggct
    20761 ttccgtttca aaaatatgca aagctgagtg cgagttttga gtgtaagatt cttttaattc
    20821 tttcactaaa cttgtgactt ctgcttcgct gagatttaac agtccgctta attcttcatt
    20881 actgatccct tcctcgccaa caataaaaag aagggcttca agttcactta atttcgtcat
    20941 gttcggtatc tcctactgct ggataaagca taattgattc atagttttct ttttgttgcg
    21001 caatgatctg cccttttttc atcaattcta gcaaagccat aaaagtagtg acaacttcac
    21061 ttttagaagg tgactcaaaa aaagaatcga aagtacagcc atgcgcattt ctttttatac
    21121 gctcttcgat aaataccatt cgttcttcga tcgttgtgtc atcgggcgtg atcgtttttt
    21181 ccactttttg agaaaatttc ttacgttcta agattttctg catggcacgg atcaaatcga
    21241 tttttttgac ttgtcctcgc ttcaacggct tttcagcatc cgctaaccca tcgatgttca
    21301 taggttcttt tgtgtaataa agacttcgtt cctctgcttt ttctgtcagt ctttcagctg
    21361 catatttata tttacggtat tctaaaagct gagtgaccaa ttcttctcga ggatcttctt
    21421 cccataattc ttcatcgtct gtgccgaatt cttggacagg aagcaatgtc ttgcttttga
    21481 ttgccatcaa tgtagcagcc atcactaagt attctcctgc aacagctagc tcgagtgttt
    21541 tcattgtatg gatataattc atatattgct ccgtgatcgt agcgatcggt atatcatata
    21601 tatcgatttc catttgctga atcagatgaa gcagcagatc gagaggaccc tcgaatacat
    21661 ctaatttaat attgatctcc gtcaactcat tcactctttc ttctttttct ttgctagcca
    21721 ttttccaatg taaggctctg tgatttcagt tgcacggatg gagacatccg ggtacttttc
    21781 ctgtaattca tctaacattt gaaagcccat attctcaccg cgataagacg gattcaaaga
    21841 aatgtcatgg atgatcagct gatcgttcgt tgcccagtaa ataccaataa tcccttgaat
    21901 gttggttgaa ccttctggcg taaagaaaaa aagttcataa tcgtcttcag attcgtacgt
    21961 atcaatctcc ttcaacaaag aagttttacc tgtcagtttc ttatggaaac tcaatagtcc
    22021 catagcaatt ttacggtttt ctttccggta atgtgttaac atcttctcac cttcctatga
    22081 ctaagccctt ggaaaatgct gcttataaac atccgtcatt cttttcttcg tgatatgtgt
    22141 ataaatctga gtcgtagaga tatccgcgtg acctaacaat tcctgtactg tccgcaaatc
    22201 agctccattt tctagcagat gtgtggcaaa gctatgccgc agcgtatgtg gtgttacttc
    22261 tttgtaaatc ccagcctctc gtactaactg cttcagattt ttccagattc cttgccgaga
    22321 aagacctttc ccatgattat tgacaaatac atgcatttca gatgcgtcct ttacaagtaa
    22381 tggacgtgct tcgtctaagt agcgttccag ccattggatc gcataatcac ctaaaggaat
    22441 gatccgctct ttatctcctt ttccaactgt ctgtaccagt ccaagagaaa gatgaagatc
    22501 tcccaatttc aatccaatca attcactgac gcgcatccca gtagcataca tgacttccaa
    22561 gattgcacga tctcttatcc ctaacgtttt tgtcgtatca ggtgcttcaa tcagcttttc
    22621 tacttctgtc agagtcaatg tacttggtaa tttctgtgct ttcttcggcg tatcgatatg
    22681 ttgcatcgga tcatgatcag tgatacgctc ttgccgtaaa aactgatgga atcttctgag
    22741 acttgagatc atccgagtaa cagttgctgt cgcttttttt tcttcatgca acttctccag
    22801 aaaacggatg actaaaaagc gatcgacatc ctgccatgaa gcaattttct gctcctgtag
    22861 aaaatgcaag tactgttcca aatcacgttc atagctttgt cgtgtattgg cggacaatcc
    22921 ccgttcaata ttcaagtagt ggagataatc gttgatttgc tctttcataa taatccccct
    22981 catgcctctc tatcatatca gataccgctt cattctgata gtctttttcc ataatctgag
    23041 caaagaaaaa gccgtctaga cactcagacg gactggttt
//
LOCUS       DAPBAF010000045        22744 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.045, whole genome shotgun sequence.
ACCESSION   DAPBAF010000045 DAPBAF010000000
VERSION     DAPBAF010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 22744)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22744)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22744
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.045"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(50..1423)
                     /locus_tag="RD451_002137"
     CDS             complement(50..1423)
                     /locus_tag="RD451_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDT7567371.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            complement(1423..1818)
                     /gene="rbsD"
                     /locus_tag="RD451_002138"
     CDS             complement(1423..1818)
                     /gene="rbsD"
                     /locus_tag="RD451_002138"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HDT7567372.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            complement(1846..2763)
                     /gene="rbsK"
                     /locus_tag="RD451_002139"
     CDS             complement(1846..2763)
                     /gene="rbsK"
                     /locus_tag="RD451_002139"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HDT7567373.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            complement(2871..3884)
                     /locus_tag="RD451_002140"
     CDS             complement(2871..3884)
                     /locus_tag="RD451_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HDT7567374.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            complement(3965..4564)
                     /locus_tag="RD451_002141"
     CDS             complement(3965..4564)
                     /locus_tag="RD451_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HDT7567375.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKEIVNNGTLSPHTAASILTNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTDN
                     MLTITKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            4750..5451
                     /locus_tag="RD451_002142"
     CDS             4750..5451
                     /locus_tag="RD451_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7567376.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            5461..8172
                     /locus_tag="RD451_002143"
     CDS             5461..8172
                     /locus_tag="RD451_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7567377.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKVAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            8623..10251
                     /gene="treC"
                     /locus_tag="RD451_002144"
     CDS             8623..10251
                     /gene="treC"
                     /locus_tag="RD451_002144"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HDT7567378.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(10311..11492)
                     /locus_tag="RD451_002145"
     CDS             complement(10311..11492)
                     /locus_tag="RD451_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDT7567379.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            11744..13267
                     /locus_tag="RD451_002146"
     CDS             11744..13267
                     /locus_tag="RD451_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HDT7567380.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKNGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAGNESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            complement(13336..14064)
                     /locus_tag="RD451_002147"
     CDS             complement(13336..14064)
                     /locus_tag="RD451_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7567381.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(14077..15357)
                     /locus_tag="RD451_002148"
     CDS             complement(14077..15357)
                     /locus_tag="RD451_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HDT7567382.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            complement(15498..16100)
                     /locus_tag="RD451_002149"
     CDS             complement(15498..16100)
                     /locus_tag="RD451_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HDT7567383.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFVLEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            16345..16551
                     /locus_tag="RD451_002150"
     CDS             16345..16551
                     /locus_tag="RD451_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567384.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            16863..17582
                     /locus_tag="RD451_002151"
     CDS             16863..17582
                     /locus_tag="RD451_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HDT7567385.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(17663..18346)
                     /locus_tag="RD451_002152"
     CDS             complement(17663..18346)
                     /locus_tag="RD451_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HDT7567386.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            18564..20750
                     /locus_tag="RD451_002153"
     CDS             18564..20750
                     /locus_tag="RD451_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HDT7567387.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
     gene            21096..21506
                     /gene="spx"
                     /locus_tag="RD451_002154"
     CDS             21096..21506
                     /gene="spx"
                     /locus_tag="RD451_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HDT7567388.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
     gene            21520..21876
                     /locus_tag="RD451_002155"
     CDS             21520..21876
                     /locus_tag="RD451_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase"
                     /protein_id="HDT7567389.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
     gene            22549..>22744
                     /locus_tag="RD451_002156"
     rRNA            22549..>22744
                     /locus_tag="RD451_002156"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT         7801 a         4027 c         4420 g         6496 t
ORIGIN      
        1 aagactgaaa tatgtgataa acatctcata cttcagtctt tttcattaac tattcataag
       61 acattaggtc ttcatcaaac ccgctaacga gagtagtgat cattgctacg actagactaa
      121 cagccagtcc tgctaagtac cagaaaaaag taccggaaat gaatgcaggc aatgtggtca
      181 gactaccaaa tacaaaagcg atcgctttca cttgggcaaa tcccattaca gctccaccag
      241 cagctgcacc aatgcaagca gcaacaaatg gttttttcaa tgggatcgca attccgtaaa
      301 cagttggttc ggtcactccc gcaagtaaaa tcgaagcaaa agcagaaccg gagatcgaac
      361 gggtttttga acgtttactt cgcagaaata cacctaaagc tgcaccagcc attccaaaat
      421 tggctgctcc tgtcaacgga acgattcggt cgaacccata agcagagata ttactgatca
      481 tgacagggtt tacagcccat tggataccaa atattaccaa aatattccaa ccaccagcga
      541 tgattgcgcc actgatcggt ccgttaatat ccatcatcca agtaattgcg gcagctaaac
      601 cttcgccaag gtaaacaccc gcaggcccga ataccattaa cgtcaaagga accgtgataa
      661 ctaatgaaag taaaggtaca aatactaatt gcatattttc gcgaatatat tttttgagga
      721 atttttcaac aaaagaataa aagaaaatac ctaaaatcgc cggcatgaca gtagacgtat
      781 actgcatcag tactacagga atccccagaa aatcagtagc tgctttgcca ctgtctgaaa
      841 gtaaagaggt cagattcggt tcaatcagtg ctgcagcaat gacagccgca atatatccat
      901 tcactttaaa cgttttggca gcagaaaaag caagaaagat tggcagaaaa taaaagacgg
      961 cattcgacgc agcagacaaa atatgataag ttccgcttgt ttcactaagc cagccaatcg
     1021 tagtcgctaa aacaaccaga ccttttaata taccagaacc ggcaaacagc ggaatgatcg
     1081 gcgtaaagat ttccgatatc aaaccaaata gtttttcgat cggatttagc ttttctttcg
     1141 gagctgaatg atcgatttga cgcgtcaatt ccttgtaagc aggagccaat ccctgatcca
     1201 tgattatttc tgcatatcta tcgagtaaaa tgaaatactt aatggaaggg atttgctgtt
     1261 ttaatttttc tgcattggct actggctgtt ttttcaattt gatacgaagc cgagtcgcac
     1321 atggaaggac agaatcaata ttgtcttttc ctcccaactg ttcaatcagc atatgaatct
     1381 gctcggacag taccatctgt tcaggattca ttgtcgtttc cattagaaga ccactccact
     1441 cactaatata atattggcgt aaggtgtcat ttcgcctgta cgaataaatg catgacagtt
     1501 attcaactct tttttcattt cttcatgtgg gataaagcta atcggtgtat ctggtaacaa
     1561 taatttgatt ttttccaata tttccgggtt cattgtcttt atttcttccg ccaattcaat
     1621 cgattgtacc tcaagttctt ctaaaacgtt ttctaaaaca gataaaaaac ttggaagacc
     1681 gtttgagaca gccaaatcta ttttttcagt accaaagggg acaggcatgc ctgcatcccc
     1741 gatacttaat ttatcaaagt gccccatttg tgcgattact cgtgaaatat ctgaattgat
     1801 tacttttcct tttttcatgt ttgtttcttc ctctcattgt taattttaga ctgctgattg
     1861 ttctaaagct tcgcggtaag ggatagaagg ttgcgcacca taagactgca cagcaacaga
     1921 agaggctaga tttccataaa ggatcgcttc tttcaagtta ctaaggtctg gctgaagtgt
     1981 gctgcttaat gcgccaataa atgtatcacc tgcggctgtt gtgtcaacgg catccacttt
     2041 aaaagcaggg acgataccgt gttctttttc tgtatgatag aaagcgccgg cactgcctag
     2101 tgtaatgatt actgttccaa tacctaattc atggagtttt tcggctgctg cgaccaaact
     2161 gttatgatct gtcactctga ttcctgtaat gatttctgtt tctgtttcat ttggtataat
     2221 gatatctgtc ttttcaagta gttcagtagg aatcgtttca cgagctggtg caggattcag
     2281 gatcgttgtt tttcctgcgt cttttgcaat agaaaaagct aggatcgtcg catctaagct
     2341 actttcaaac tgagcaataa taaagtcact gtttgtaatc agttgcttgt tttttaggac
     2401 ttcttgttca tggaaagcat tatttgcccc tgcatggatc aagatactat tttctcctgc
     2461 tgcgtctacc ataatcattg cttgtccggt tgtggcgcct tggatttcag ctatcccaga
     2521 tgtatcgatg ttttcttttg tcagtagatc taataactgt tgtccttcgc tgtcagcccc
     2581 aacgcctcca ataaaagatg tccgtgcgcc tgaacgtttg gctgccactg cttggttggc
     2641 acctttacct ccgccagcgt gaaaaatctc atgcgcatgc atcgtttcgc ctggcttggg
     2701 catgttggtt aaacgaaggg tagtgtccat attaatactt ccaattactg taaccgtgtt
     2761 cattttacaa acctccaact atctcattta ttttgatggg aaaattattt tttaaaacgt
     2821 tttagtaaaa cgttttaata gttcgataaa aatatagcac accttgaaag ctatttcaag
     2881 ggtgcagttg aaaatctttt ttctaatcgt acaggtaatc ttttttcttc ccattctttt
     2941 tctgggaatt ggatccgatc taacaataac ttggcagatg tttgtcccaa ttcgaagatt
     3001 ggttgtgcga tcgttgtcag tttcggcttg atatactcgc acatatctat attatcatag
     3061 ccaataatgc tgtagtcttc agggatgctt tttccagctt cctctaatcc gcgatataat
     3121 ccaaaagcta attcatcatt taaagcaaac acaccagttg cagcagaatc aagaagttct
     3181 gctgtgatct ggtagccacc ttgttttgag aactgtgtag gtaagaggat cagttggtcg
     3241 tgagggattt ggtaaacatc aagagcagat ttaaacccct caatccgagc gtggacattt
     3301 tccggtggat tttcaggata gacaagggcg atcgtttgat gtcctagact aagcaagtgc
     3361 atgcccgcta ggtaaccacc gcgaaaatcg tctgttcgta cggcatcact aaatccttca
     3421 gattttttct gatccaaaac aatgaagggc cggccttgtt ttttcaaatt ttcgttgatt
     3481 gcatctgtag agacagcaga agtcgcgata atgaatccat ccacacctcg acgtgtgagc
     3541 tcggctagat attcgatttc tttttgatga tcagaatcag cattacataa tatcgtgacg
     3601 aaattctgct tatacaagat atcctcaatt cctcgcatca gtgtactgaa gaatggattc
     3661 gtgatatcag gaacgagtac accaattgtt ttcgtttcct tggtaatcat ttgtctagca
     3721 aaatagtcag gctgatagcc taattcttct ttggcagcta aaactttctg aacagttttc
     3781 ggactgaatt tctccgtatt tccatttaat atcaaggaga cagttgtgat tgaaacgccg
     3841 gaaagtttag cgacttcttt gattgtgatc ttttttttca ccatgttcat actcctatct
     3901 aaatcctgtg gttattttcc catgaaatca aaaagaagta aatgaaaatc acgtgtgcca
     3961 gtacttattt gctttgttgg atagcttcga ttatttgttt cgttgagcgt actcgtgcag
     4021 ttttcggaaa tatctttttt atgaacaatt gatgggattc tttgtcacga tcactgcaag
     4081 catcttcagc aagcacgata tggtacccgt gttgaaaggc atctaatgca gtagcatata
     4141 caccgtttgt tgtcgctaca ccgcttaaaa tgatagtttc gattccacgc cggcgaagtt
     4201 gaagatcaag agaagtacca aaaaaagcac ttggattgta ttttgtgata gtcaacatat
     4261 tatctgtatc tttcaaagaa tccttcaaaa gtaaatcagt gaattctgga ggtacagaag
     4321 cagtcattcc acccatatca gtttgttgac tcaaataagg gaaagtggag atgtctacgt
     4381 tcactaaaac tttcaaggca gcggtacgtt tcaatgttct tactaacaaa tcattgtttg
     4441 tcagaataga tgctgcagtg tgtggagaga gtgtaccgtt atttacgatc tctttttgca
     4501 tgtcgatcgc gacaaaagca gtttttgata aatcaaaaat catattttcc tttaaatcat
     4561 tcatgatgtt ccttctttca aataacaatg ttttttatgt aagtaaatca taaatcgttt
     4621 atttgtcaac taaattaaag gattcctttc tttagtctag agaaattcag tggtaaaata
     4681 aataagtgtg agaaaacgca ttcgatgcat agatatagcg agaaatatcg tgaaaatgga
     4741 ggaatcagag tgaagtatgt cgaagtaaaa aatgaataca aacgatacaa aatgggagaa
     4801 acgaccatta cagcaaatga cgatatttct ttttcaattg aaaaaggcga attagtgatt
     4861 atacttggtc caagtggagc aggaaagtca acgattctta atattttagg tgggatggat
     4921 acacctgatg aaggtcagat cattattgat gacacagata ttgcgcaatt ttcagataaa
     4981 cagcttactg cttaccgacg aacagatgta gggttcgttt tccaattcta caatctcgtt
     5041 cctaatctaa cagcaaaaga aaatgtggaa ttggcaacgg aagtttctcc tgatgcgctt
     5101 gatcctgtag aggtattgag gcaagtgggc ctagctcatc gattgaataa ctttccgtcc
     5161 caattatcag gaggcgaaca gcagagggtt tcaattgctc gtgcactagc taaaaatccc
     5221 aaacttcttt tatgtgatga accgacaggc gcgctggatt ttgaaacggg caagcaagta
     5281 ttgaaattat tgcaaaacgc tagcagacaa cacggcaata ccgttttgat cattacacat
     5341 aattctgctt tagcgcccat cgctgataga gtcattcaca ttaatgatgc taaagtaagg
     5401 tctgttgaat taaatgatca tccttcatcc attgatgaga ttgtatggta gggggatttt
     5461 atgaaaacaa gaacatatct taaagcaggt tttcgcgaaa ttcggcaatc taaaggacga
     5521 ttcattgcaa tcatccttat tgtcatgcta ggaacacttt tatttgtagg tgtcaaaact
     5581 gctggacctg tcatgcaaaa aacgatggat cactatgttg gtacagcagg actttctgat
     5641 ttgcaaatcg tttctactgg tggcttgaca caaaaagata ttgctcaagc agaaaagatc
     5701 ccagatgcaa aagtagaaac aggaaaacag atctattatt ccaatactgg caaaaacgaa
     5761 gtgattcaaa tattttctta taacaaaaat aacaagcaga acaagctaca attaactgat
     5821 ggaaaactcc cggaaaaacc aaaccagctt gtattggatg aaaaagcgga agatgaaggg
     5881 tataaaatcg gtgatattta tcagattgat tcagatgaat tgaaagaaaa agagtatacc
     5941 atcacgggct ttgtccgttc tccattgttc atcaacaatt tggagagagg atacgcgaac
     6001 gtcggaaatg gtagcgtcga ttattttgtc tatttacctg aatccgtttt taaaacagat
     6061 atttattctg tcttatatct tgattttaca aacgtaaaga atttgaatac gtacagcaaa
     6121 gcttacaaag ataaaatgga gcaaaatcaa gaaaaggcag aaaagtattt acaagatcga
     6181 cccgaagaac gcttagaaga gctgaaaaaa tcggccaacg aagaattaga accggcacag
     6241 caaaaaatag cggatggcaa agcacaaaca acgcaagcaa gaacacggtt agaagatgct
     6301 aaaaaacagt tagcgcaaca gtcagcaact atccagcagc ttcctgaagc gcaacgaaca
     6361 atcgctgttc aaacattatc tcaacaagaa gctcaacttg ctgaacaaga aaggcaatta
     6421 gttgagaaag aacgtgaact ggcctctgca gaggaagaat tgaatcgaaa tgcagaaaaa
     6481 attgaaaatt taactaaacc atcataccta tacaatgaac gttcagaaaa tgtcggtttt
     6541 caagaatttg gtgatctgtc tgatcgtatc gctgcgattg ccaatgtttt tcctgttttc
     6601 tttttcttta ttgccgcatt gatcaccttt acgacaatga cacgtatggt agaagaaaac
     6661 cgcagggaaa tcgggacatt aaaggcgtta ggttatacga aagttgaaat cgcaaaaaaa
     6721 tatgcaatct atgcaagtct agcctcaggg ataggtattg ttttaggaac gatattagga
     6781 acgaatcttt tgccaaggat catttttgag ctgtctaacg agcggtatga tattgggagt
     6841 gcgcttattt tttatgactg gccgccgatt ttacaagcag ctgccgcatt cttcattgcc
     6901 gcatttggcg ctgcaatgat cgttttattc aaagatttaa gagaacggcc tgctgcattg
     6961 cttcaaccga aagcaccgaa gccagggaaa cgcatttttc ttgaatacat cactccgctg
     7021 tggtcacgcc ttagctttaa tcaaaaaatc agttaccgaa atctcttccg atataagtca
     7081 agaatgctta tggcgattat cggaattgct ggatgtgccg ggctgatggt tgcaggcgtg
     7141 ggattgaaag attctctaag ttctgtttca gccaaacaat ttggaccgat cattgactat
     7201 caagcaatcg ttacattgga ttcatccacg gaagatagtc gtcaaaaagc agcggatatg
     7261 ctgcagaagc aagaaaaagt aaatgagatc ctagctattc atactcaaac cgtagaattg
     7321 agaaaaaaag gacatgcttc gcaaagtctg acagtgatcg taccaagtaa aacagctgat
     7381 ttggatcgtt ttatccattt aactgatctt gaagagaacc cacgctcctt gcctaaaaca
     7441 ggaatcgcta ttacgcaaaa agtagcagaa ctatttgact tatctacagg agatcatatt
     7501 tcgctttatg atgaagatca aaaagaatgg aaagtcgaag taaaagaaat cgtgaaaaac
     7561 tatctaggta gctttattta tatgtcccct gaatattatg cttcagttac tgatcaatcg
     7621 atgatggata atgcattttt gctgcgtaca gataagatga caacaaaaga agaagaaatg
     7681 ctttccgaga aactgcttgc cacagacgct gtgacaaata cgtctttcat gtccaaacaa
     7741 atcgaaacgc aagaagaatc aatggcgaac ttagactcgg ttgtcttaat ctttgtcgta
     7801 ttatcaggac tgctggcttt tatcgtcttg tataatctaa ctaatatcaa tatttccgag
     7861 cgtgtacgcg aattatctac aataaaagtc cttggatttt ttgataaaga agtcacgatg
     7921 tacattgttc gagaaaatat catctttact cttttaggaa tcatcggagg atttggtgta
     7981 ggatatatat tgactgactt catcttgcaa caagcgtcta tggagaatgt catctttcca
     8041 ttagtgatca catggtgggc ttatgtctta tcagcaggat taactatcgt atttacggtt
     8101 attgtgatga ttgttaccca tttcaaatta aagcatatcg atatgattga tgcgttgaaa
     8161 tcgaatgaat aaaaacagag gttgtgaaat cagcggtttg acctgagtat tagagaaaca
     8221 aacggcaaaa tagtttttca tattttgccg ttttttgagc taataccgaa ggacagctga
     8281 ttgaacacca tgaatcagag gttgtaaaaa agccgtcctg catcgagcaa aaagaatact
     8341 caaataaaat tagctcctca tgttttacat ttgagaagac tgattgccgt agataaaagc
     8401 ttttgaacac catttataga agaaacaaga atattttgct attttaaaca agaggataga
     8461 caaatacatg tctgatctct tgttttttat tgggcaacag acctcttaga atgtataaag
     8521 ataaatttta caaacgcttt cggttcagtt ataataataa atgataactt gtatatataa
     8581 gttgtggtag gtaataaatc agttgaatgg aggtaaatat ccatgacatt taaagacaaa
     8641 gtcatttacc aaatctatcc caaatcttac aaagacagta atggtgatgg aattggagat
     8701 ttaaaaggaa tcaaagaaaa actcccgtat ctgaatgatc taggcatcga catgatttgg
     8761 ctaaacccta tttatccaag ccctcaaaaa gacaacggtt atgatatctc tgattacaca
     8821 gccatcgatc ctatctttgg tacgatggag gaattcgaac agctaatagc cgaagcaaag
     8881 aaataccgga tagaaatcat gctcgatatg gtgctgaatc acgtttcgac agaacatgaa
     8941 tggttcaaaa aagcactagc aggggaccag cattatcagg acttcttcat tttaagagaa
     9001 gagccaacgg attgggtatc aaaatttggt ggaagtgctt ggtcgccatt tggagatacg
     9061 gggaaatatt atttgcactt atatgatcgg acacaagctg acttgaactg gcggaaccaa
     9121 gcagtaagag aggaactatt caaagttgtt cgtttttgga tggaaaaagg ggtaaaagga
     9181 ttccgtttcg atgttatcaa tgttatcggt aaagacgaac aattgaaaaa taataaagaa
     9241 aatgatggca aacctgaata tacggacaaa ccaatcaccc atacgtatct aaaagaattg
     9301 aaccaagcaa cgtttgggac ggattccact atcatcacag tcggtgaaat gagctctacg
     9361 acgatcgaaa attgtatctt gtatacagaa cctagtagag aagaattatc aatggtcttt
     9421 aatttccatc atttgaaagt cgattatgaa aatgggaata aatggtctac tcctccattt
     9481 gattttgcag aattaaagcg actatttcat acatggggag aaaagatgag tgagggtaac
     9541 ggctggaatg ctctattttt taataatcat gatcagccac gtgcgctcaa tcgatttgta
     9601 gctatcgatc agtatcgaaa acaaggagca gagatgctag caaccatgat ccatttgaac
     9661 cgtgggacgc cctatattta tatgggagaa gaaatcggca tgatcgaccc agactattca
     9721 tcgatttccg actatattga cgtagaaagt ttgaatgctt ataagttact ccttgaacaa
     9781 ggattcacag aaaaagaagc gtttcgtcgg atcaaagcaa aatctcgcga taactctcga
     9841 acacccatgc aatggtcaga cacagaacaa gcaggattta ctacagggaa accttggtta
     9901 aaagttggag gcaagctaga agagattaat gtagaaaaag aactatcttc tgaagattct
     9961 attttgtcct attacaagaa attgattcgg ctgagaaaaa catatccaat cgttgcacaa
    10021 ggagattatc atgcttatga agcaaatcat ccggaagttt atggctttct tcgccaattt
    10081 gaaggacagc agctgcttgt attaacaaat ttctatgata aagatacaag gatcgccatc
    10141 ccagaaggat tcacagaagc caatattctt atcgataatt attccgatac tgttcttcat
    10201 caaagtctgg agctaaaacc ataccaggca attgctttgc tgaaaaatta aaacaaaaac
    10261 acaaaacgtc gttcctacga gctattctcg taagatcgac gttttgtgtt ttatttaaaa
    10321 taatcttctt cagaaaatga agagttttca tactctcctt tatcgccata aaatttattg
    10381 tagcgttgtt tgaatttacg gaaaataaaa gtaacgagta atttgactaa cgtatagata
    10441 ggaataccaa aaataacgcc cacaattccc attagatcac ccatgacaag taaaacgatt
    10501 aagatcgtaa tcggatggat ctgtaaacga tcacccatta ctcgaggaat caccaagtca
    10561 ccgtggagaa gttgtacggc aaaccagaca atgacaaatt tgacagccat aaaagtagag
    10621 tcttggaatg caatgatcaa acctggaaag aaggcgataa acggcccaat atatggaatg
    10681 atacataaca acccagcaga aatagctaaa acactagcaa attctaatcc gatcagtaag
    10741 aaacaaaccc agtagactgc tccaaggata aatgaagcaa tgatttgccc ctttagaaat
    10801 gaacccaatt gttgattagc aatctttgtc aaatttttaa aatctgtacg aaatgctggt
    10861 gggacaatcg ctaaaactga ctgataaaat ttttgaggat ctctcaaaag gaaaaaagcg
    10921 acaattggac cagtaaataa agtaataaaa atagctgtaa cagttgaaaa aatgttgctg
    10981 atccgttgtg cgccactttc ccaataattt ccaataaatc cagctatatc agacgtcacg
    11041 tcgtcaatag aagcgaaaaa ttgattaaat gaatcggcaa aaggtgtttt ctccaaaaat
    11101 tgtcggagac tctcttgaaa atcttgaaac aaatctggca aactactgat caatgtcttt
    11161 gcctgttctt caagaaaagg aataagccat atgcttccaa gccccaataa aaataaaata
    11221 atcacataaa cgataatgac tgacaagttc ctcgaaaggt gcttgctcaa acgtttgatg
    11281 actggttcca aaagataata caagatcagt gcaaacaata atgggggcaa gatagtagcg
    11341 ataatgattc cgacaggctt gaatataaac gagatctgat ggaaaaaata aatgatcagc
    11401 gcaagtaaga taactattcc taaaacatag taagaggttt ttcctcctaa aaagcggatc
    11461 aaacgattcg ttgtatctgt ttcttttttc actctttttc ctcctttatc tataaattca
    11521 ttatagacaa aagcgggtat aaaaggaaaa tgatagaggt tgattgcaaa aatatcgtca
    11581 atcattcata taaactttct catcaattaa aataagaaaa cgcttgacag ttcttttaac
    11641 catatgataa attaaatcct gttgctaaaa cgtaactatt acggtttgcg aaaagcgaat
    11701 cggaacattc aaatgaaaga agatgagaag aggagtgtca taaatgaaac gattgatagg
    11761 tatattggcc atgctggttt tagcaggtat gttaactgct tgcggggcaa gtgggaaagc
    11821 cgaggacagt aaagaaaaat tgagcgtgat gacgaccttt tatcccatgt atgattttac
    11881 aaaagcaatc gtcggggatg aaggagaagt agagttattg attccagcag ggactgattc
    11941 ccacgattat gaaccttctg ctaaagacat ggcaaagatc caagatacag atatctttgt
    12001 ttataatgat gaaaacatgg aaacatgggt ccccgcaatc caaaaaacat tacaagaagg
    12061 caatgtccat acgataaaag cgacagaagg tatgctttta cttccgggaa gtgaagaagg
    12121 acatgatcat gaccatgaac acggggaaga aggccataca catgagctag acccacatgt
    12181 atggctagct ccaagtttag caatcaagca ggtagcaaac atacgtgatc agctgattga
    12241 agcttaccca gaaaaacagg aagtatggac aaaaaatgca gcagcctata ccgagaaact
    12301 tcaagcactc catcagcttt atcaagaaac ctttaagcaa gcaaaacaaa gatcttttgt
    12361 cacgcaacat gctgcattca actatctagc gttagaatat ggattgaatc aagtatcgat
    12421 tgctggtctt tcttctagtg aagaaccgtc tgcggcgaga attgctgaac tgaaacactt
    12481 tgttaaagaa catggaatca actatattta ttttgaagaa aacgccaaag atagtattgc
    12541 cagaacgtta gcaaacgaag caggtgtatc tttagaagta ttgaatcctt tggaaggatt
    12601 gacgaatgaa caaatagaaa atggagaaaa ctatctttct atcatggaag caaacctcga
    12661 agcgttgaaa aaaacgacag agacagaaaa cccgctagaa gatactttga cccccaaaaa
    12721 agaaaagagc gtctacaacg gttattttga agacgaggat gtacaagatc gctctctttc
    12781 agattgggca ggaacttggc aaacagtaga tacgtatgta gaagatggga cttttgatcc
    12841 tgtttttgaa tataaagaaa aattgaatca ggataagaca gcacaagaat ataaagaata
    12901 ttatacgaag ggctatcaaa cagatattgc ttcaatcaag atcagtgaga aagagatggc
    12961 atttacgttt aagaatggaa caacgaaacg ttcaaattat cgttatgtag ggaaagaaat
    13021 cttgacctac gaggcaggaa accgtggcgt aaggtatcta ttcgaagcag aagataagga
    13081 aagtggcgct tttagatata ttcaattcag tgatcacacg attgcaccgg ctgactccga
    13141 acattttcat ttatatgcag gaaatgaaag tcaagaagta ttgctgaaag aaatggagaa
    13201 ttggccaaca ttttatccag atacaatgga tggacgtgaa attgcacagg aaatgctttt
    13261 gcactgatag gcaaaaaaga accgaagggt ttggatcggc tggtcattta gtcggtccaa
    13321 actattcggt tctttttatg aaatcaattt ctttaatcca cggatagagg ctgggatggt
    13381 ctcgccgttt gccaacgtga cttctctggt ttttttatta atcgaccgca cattttgtgt
    13441 attgataaca taggatttat gacaacggat aaaattccga tgcattttct cgatttcttt
    13501 gatcttctca tagaattgta attgggcatg agtcaaatgg acttccagtt tatgtggcgc
    13561 tcctagcgaa gtagaaaaat attggatgtc tttgatcggt aaaaatttga tctcatcatt
    13621 aaactctatt ttgaagatat ctttttggat ttgggacatt tgaaaatctt cgaaaatttt
    13681 gctcaggata tgctcgacat tttcttttaa atcataaaga tcttctttga cgatataatc
    13741 agtcggttcg atgttgcttt ttaagatttt catcgacatt tccgtatggg aagtcacata
    13801 gattattttt cctaaaggat ctaattcacg gatcaattta ccgatcgcta caccatccat
    13861 ttcactgtct tctagttcga tatctaaaaa gtaaatacca aaagaagaag ttctgatctt
    13921 ggctgcattg agaagttctt ccggatcaga ggtagaaata tggacataac tgtctaagtt
    13981 ttcaatcatg attctatttt tgatcaccgt tgataaaact tctaattgtt ttggatcgtc
    14041 ttcacaaata taaatgggaa tcatatcatt actcctttat tttatttgta tataaatcgt
    14101 ttgagaaaaa cgctggtttt caattgatgt ttcaaggaaa agataaggat tggtctttgt
    14161 caattcatcc aagataaaca agccaaggcc ttcgtttttt ggatttgttt ttgttgagaa
    14221 ccctttttgt ttcaactggt ttaacggtaa tgtatttgtt gttgtattga tcacacgaat
    14281 catcacggaa tgattcttct tgagtatggt caattcgatt tttttcttct ttgcagcact
    14341 agctccttca atcgcattgt ccaagataat accaagcata cgtacaaggt ttaccgtatg
    14401 tttcgtatcc agttcgattg gctcaggaaa atgaagctgg acgatcaacc ctttttcctg
    14461 tgccatcatg agttttaatg acagtaaact acggatctca ggaactttca tattatccaa
    14521 catacttaga ttggccggaa aaaggttcat catctggcgt gtaggtaata tcgtttgatc
    14581 ataataagac cgtaatcctt ctaagtcgcc ttctgaaata tagctgtgaa gagaaaaaag
    14641 cagattttgg taatcatgtt tgaattctct caagtcttga tagttttttt ctagatcttt
    14701 gatataatcc tgttgcatcc tgacttgttg ctctaataac tgatcagcta atttcttatt
    14761 agagattttc caataataaa ccaagatgat caggccaaca cacagatata gaatgaaaaa
    14821 actcgtattc aaagctaaga catcaggtgt ttcaccagaa aaacgggtat aaaaaataat
    14881 gatatagtat gtaaataata tcaatgtccc gatcgtaccg atcatacggc ggtccacagt
    14941 gtgaaaccaa gtctctaacg atttttttaa acaaaaagct aataaagcag ataaaaaagc
    15001 ggataagaca atgtgaaaat actgcaatga atctcctggt tcaataaccg aagatttcaa
    15061 aacaaaaaaa tcgccgatgc ttgttaagtg atctcctaaa agcgacgtca ataacccaaa
    15121 aggaagcgcg taaaccaatt gttgacgcga agtcgaaaag aagaaaaaag taagcatcag
    15181 cattcctata gcaattagag cagtaaaaat ccctaaaatc gaatagaccc atccaatcaa
    15241 aatacaagaa atcagaatga ctcccgcaaa cagatatttg tatcggatgt gatggtcaat
    15301 caataagata caaattgtgt aaatcaaata ttgcaacgct atggaccata aaaacataaa
    15361 gtacagctcc cattgatttt taccaaatta tagcacaatt ggcgtattat ttttttaatt
    15421 tttcagggat tttgaattca gaactcatac caaagcagca gccagataca aaaaagtcag
    15481 ataagttagt taattgttta atgattgttt ttttcatgaa agattcctcc aaaattcatc
    15541 aagtagtttg taataggaag caacgtagct atttctaaaa caatcccaag tagcaaatag
    15601 gtagaaaagt aagaagctga gaaaaataac gtaatgagag aaaaaattag aaacatgctg
    15661 atcgccttct ttaataatgg gggacgtttc tcgggttcaa tgggattgat tgctgtacct
    15721 cttgatccat agcgaagcag taacaaaaag cagctgatta acaaaaagac catcattggg
    15781 aaggagatag tcaattgcag atgtttcatc accaagggaa cgccccataa ataaagtagt
    15841 gtccacagca gacaaacgaa ttcagagtcg gaatgcaatc cataagcata tctgcggatg
    15901 cagatataag aaagaaaggt gattcctgtt tccgcccatg agcctgtcac cagagaaaag
    15961 actagaacga ccgctagttt tccaagatta ttcaataaaa cttctaagac aaattttact
    16021 tggacataca ccatatcttc ttccgatttg tctccgctga ataaggcttc taataatttg
    16081 ttcacaactt tatctttcat ctcatacgta cctccaccac aaattttatg ctaaaaaaaa
    16141 taaaaaacgt cttttgtttc ataaaaagtg gttttgacat caaaaccgtc atgatctcct
    16201 aaaaaaatct tcgttttcca agaaccttac caaaaaaagt gacagttttg atacgaaaag
    16261 tactttttat gacaagtttg tgctttttcg agtgatttat gttaaaaaat tactgacctt
    16321 ataaaaggtg atggagggat tcttatggaa aatgaacaat tgtttgaagt cggcgaaaca
    16381 tatgcattta aatctgattt atttgaatca ccaataaaag gaaaaataga aaaaatctat
    16441 gaaaatagtg tgatgatacg tgtcatgaaa tgcgcagtag aagacaatga taccgctcat
    16501 aatctgcact ggcagttagt tgtacgcaaa tcaagtacaa tagaagaata aaaacagata
    16561 aaatgttgag agcataaaga ggttgtgagt ctcccgttta gctctgagtt acaaggaata
    16621 atgttaaaaa acagcttttc atgttttatg aatattgcct tgtgaccgag gtgttggcag
    16681 gagaatactg tttatttgaa aaaagggctg cgacaagact tttgtcacag cctttatttt
    16741 catgaatagg agttactttt ggctactttt agagaagtag cttttaagga gcagataaag
    16801 tcaaggcttt tatttctata aatgaagtag taaaatgaag aacagatttt attacaggaa
    16861 ggatgccgat aattgtgatc attgttgcag gaacgatcgg tgcagggaaa agcacactaa
    16921 ctgaaatgct tgcccaagat ttagaaacaa aaccttttta tgagaacgtg gaagataatg
    16981 aagtattgcc gctattttat tctaatccag aaaagtatac ttttttatta cagattttct
    17041 ttttgaacaa acgctttttg gcaatcaaag atgctttcag ccatgatgac aacgtactag
    17101 accgctccat ctacgaagat agtatgctgt ttcatttgaa tgcagattta gggcgtgttt
    17161 ctgaagtaga agtaaagcag tatgaaggtc ttttagaaac gatgctgaag gagttagaag
    17221 aaatttcgcc acaaaagaaa ccagatctac tggtttatat tcgtgtatcc tttgaaacta
    17281 tgttagcgag aatcaaaaaa agaggccggg aatatgaaca gctagaacaa gatcctgaac
    17341 tctattccta ctataaagaa ctcaatcgac gatacgaaga gtggtatgaa cagtttgata
    17401 tatgtcccaa aatagtgatc gatggggaca aatatgattt cgtagccgat ccggcatgtg
    17461 gagaacaaat cgtacaagaa atcaagatgc gggcaaagaa aatgacagaa gaggcagatg
    17521 cccagtcgat ccgctacact acaaataacc cgaaagcaaa gggaatcttt acaactaaat
    17581 aatataaaaa ctaagcaaat tgctcactcg cagatatttc tctgtgagca gcatcttgct
    17641 tagttttttt gattcattga gatcaaatag tgaaccgatt cgtatgataa aattgccata
    17701 aatgaaatgt ctgagtgagg gccatgatca aaaataaaat ggaaacgatc aaaatcgaat
    17761 gggcgccaaa cagatgatga cagaaaacaa ggacaatagc tcctgcgata aaggcaagaa
    17821 cgacacttag atagtggaaa aatcgatcaa aatctgcttt ttctttagaa atacaataat
    17881 catataagtt cgttgctacc ccttttaaat ttccagttgt aaataaatta gtgtaggcac
    17941 gcccgttgat tttatcaaaa gctacccact ggatcgatgc agtaaaagca atcaaaatcg
    18001 ttactaatgc gggatgctca tggacgggtg tcaaactaac aaagaaaaaa atcactgctt
    18061 cataatatag aacaaacaag cgccagaaat gtttttcttt ttttctaaaa taatcaatta
    18121 gatactttgt tagaagaatc cctaagaaaa agaaaagggt agacaatact tttttaccaa
    18181 cacttagcca ttctccgtca aatgcttgga tgatcgatag aatgatattg ccagtttgag
    18241 cagaggcaaa agcaccatat tggatataag tataactgtc catggctcct ccgataaatg
    18301 tcagcaaaag tcctattgta cgcccctcgt gaaaggaagt ctgcattttt ttcatcacct
    18361 tttatgaata tttttgtctt ccttatctta gcataaacga ttgaaaaaaa ggaaaaattt
    18421 tcagaaaact aaaatcatat cgcttcccat tttcattttt agaaaggtct gttagtataa
    18481 agaaaaaata gacaacgaaa ctttaaataa ccaacttgaa ataaacaaat tcaaagaaga
    18541 aagatgggaa ggaaatcaat cagttgaatg aaaaagaaat tctccgatta caaaaagaat
    18601 tgaaacgctg ggagaacaag tataaaaagc ttcaacaagt ctttcggcta caagaagaaa
    18661 tcattgctac ctatgaagcg gcttatggcg aagcacccgg acttattgag gaagaagtac
    18721 aagtaaaaga aagtgaagga aacagctctt tctttaaaat gatggagaaa cgttcctata
    18781 atcgcttcaa tcaagaacaa aaagcagcta tcacatatga tatgaagaaa catcttcgaa
    18841 tcatagcagg agctgggagc ggcaaaacgc aaacaatctg tgcaaaagct gtttatctga
    18901 tgacgcaaaa acaagtagac gaagaacgca tactaatgat cacttttaca aggaacgctg
    18961 caaatgaact aaaaaaacga gtagataatt tcagccagag aaaaaccgct gtccatatcg
    19021 gaacattcca tagtatcttt tttaggatat acaatgaaat ttgtcgaaaa tttcctgaag
    19081 tagcaatgca aggaatacaa ggagactttt caaaggatac tgcacaaaaa gtgaatgctg
    19141 ttttgcaaca gctgatacgt aaatataatc tttatatatt tgatcaatat ggagaaaaaa
    19201 cgattgcttc tcggttagac tattggcaga atatgaacct ttcagtagaa gaaatggttc
    19261 agttagttaa agaaaaatat gattccattg ataagaatgc acgacagccg atatcagaac
    19321 gactgtatgg attgctcacg gaactccaag aacaaaaaag aagccagcaa ttgctagagt
    19381 tcaatgatgt actccaaaat ctgaaaagcg ctttggagaa tgaggagatc cagcattata
    19441 tcggccaaaa atatgattat ctattcattg atgaatttca agatactaat ccacttcaat
    19501 gggaaatcgt gaaacggatg acaaaggaaa acaggatcaa gttgattgtt gttggagatg
    19561 atgatcagag tatctatgga ttcagaggat cagagccagc atacatcaag aactttgaaa
    19621 aagaatatcc taccaaaact cttttcttat taactaatta tcgttctcgg gcagctattg
    19681 tccaaggagc aaatagattg atcagctata ataaaaatga tcggatacca aaggcgatga
    19741 ttccagcaca aaaagaagca ggtgttatgg aagcctattt gttttctgat actaaagcag
    19801 aaagtcagtg gctaatcaaa caaattcaga catttattca aaaaaatggg aaatataagg
    19861 aatcaatcat attataccga tcagcttcac aaacgcagca gcttgtccaa tctctgctga
    19921 aaacgaatat tccttttgta ctggaagcag atagtccata tgaaggtatc tttggtatca
    19981 agtctttcca acatttctat caaaaaattg ttcattggca aacagcactg aatctgcaaa
    20041 agaaaaatca ggcctaccag caattgctcc ggcagctgat ggcagactgc tacctgaaaa
    20101 aaagtgaatg cgatcaatac ttttctccta aatatcaaaa tatagccgtt gcagattata
    20161 ttttgtcgat aagccccaat ttaaaatcga aatctgcaga aatccgagag tttgaggaag
    20221 cgttgcgtaa aacagaccag catcaagaaa tctattcgct tgttcaaagc tatcttcatc
    20281 tgccacgtat agctaaggaa atcgaccaga gtgatcaaga atggatacga gaagaagtaa
    20341 agcagcatgc tactttcaga agactccaag ccttatcgca agaaacccaa gcgacagcta
    20401 aagaattaaa aacccgcttg attgcttaca gacaaggaaa acttgatgca ctatgtatcc
    20461 agagcattca caaaagtaaa ggtcttagtt accgaaatgt ctttttgatt ggttgtaacg
    20521 aaggaagttt gccttataac ggagcgacag aaaagaaagt aatcgacttt aatgaaataa
    20581 aagcagaacc agtaacgacg atagaagaag aacgaagact attttatgtt gcgatgacta
    20641 gagcaagaaa tcgtctgtat ctatgtgtac ctcaaatgaa aaattcaaga aaattgaaag
    20701 tatcgagatt tatcaaagaa accgggagtc gtgtgaaaaa aggaaagtga tagaagagag
    20761 ggtgtgacag aagtggtcag tttcaagaaa gaagaaggaa tgtacgaaaa ttgcttctca
    20821 aatttttgtg aaatttcagc ttattttcga agaagctatt tctggaacac agtttattcg
    20881 gaaaagggag gtgtgacaag aattttgtca cacctccctt atttattttg aaaatgagaa
    20941 tactattatc aaaatagaga atatatagaa aaattctcat tattcaaacg taaataatca
    21001 gttattttga ttttttttat attttattag ctaataattg gtattttaaa agaaattact
    21061 gtagaattgg attataatta aaaaggagtg agaaaatgat aaaagtatat acttcgccta
    21121 gctgtacttc ctgtagaaaa gcaagagcat ggttgcaagc gaatcaactt gaatttgaag
    21181 agaagaatat ttttgccgaa ccgttaacag aaagtgagat caaaaagatc ttggcagcga
    21241 ctgaaggagg agttcaagat attatttcca ctcggtcgaa aatttacgaa aagctgggca
    21301 tagattttaa cgaattaact ttaaagcaaa tgatcgtctt attcaaagaa tatccttcat
    21361 tattgagacg acctattttg attgatgaaa aaagaatact aatcggattt aatgaagatg
    21421 agatccggtc atttgtccct cgtgaaattc gatgtgttgc cagaaatctg atctatttac
    21481 aaaacaataa catcttaaat tcatagggag ggagccttcg tggaagtgaa agtctatgga
    21541 tcagcgcact gtgtaacaag tctgaaggcg aaacaatggt tagaacacca tcaattgcct
    21601 tatcaatttg ttgacttaga agaacgcgat ctaagtacag aagaagcaga agaattatgc
    21661 agttttgaag aagtgcaagc agaacagcta tttgcgactt ggtctgaggc ttttcacaac
    21721 attgcgattg acctttcctg tgtaggaaaa aaacaactga tttttttatg cacacaacat
    21781 accaatctcc tcagacgtcc tttgattatt atcgatgaag ttctatttat tggatacaat
    21841 gagcagttga tggaacagct tatcttaaat aaatagactt taactgtttt aatcaagtca
    21901 ctgagcattt catacagttg taacagtcga acacttagca tcaagcgtgt tatgtgttct
    21961 ttttttgact ttatttttct actatagaga catgctcaat ttatgtggtc aaaattcaaa
    22021 tctaggtggg gatatagagt taaaaatata ttgacatgtg taaatttaca tgatatattc
    22081 atttctgttg ttttaagtag caaagcaata aaatagtatt ttaaaaaaca tataaaatag
    22141 ttgttgacat gttagaaatg acatgataag ataactgagt tgttaaaaaa gaaccacttg
    22201 tgaagcttga ttctatcgaa aaaaacttca aaaaagttct tgacaaataa caaatgataa
    22261 gttatgataa atgagttgct gtaagatttc gaaaaacgaa atcaaaaaaa cttttaaaaa
    22321 agagttgaca attacttgtc tctctgatat gatataaaag ttgctacggc agccaaaaac
    22381 gaatcgggga acactcctga tgaagtagac ctttgaaaac tgaacaaagt aagacaaacc
    22441 aaatgtgtag ggcgtcttga ttcaattcaa gacaacaaac attttttaac aagcaagcaa
    22501 tatgctagca aacaaattga gcttaacaat cgcaagattg ttcgaacttt ttatgagagt
    22561 ttgatcctgg ctcaggacga acgctggcgg cgtgcctaat acatgcaagt cgaacgcttc
    22621 tttttccacc ggagcttgct ccaccggaaa aagaggagtg gcgaacgggt gagtaacacg
    22681 tgggtaacct gcccatcaga aggggataac acttggaaac aggtgctaat accgtataac
    22741 aatc
//
LOCUS       DAPBAF010000046        22028 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.046, whole genome shotgun sequence.
ACCESSION   DAPBAF010000046 DAPBAF010000000
VERSION     DAPBAF010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 22028)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22028)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22028
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.046"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(61..1371)
                     /locus_tag="RD451_002157"
     CDS             complement(61..1371)
                     /locus_tag="RD451_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HDT7567390.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     INFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1383..2801)
                     /locus_tag="RD451_002158"
     CDS             complement(1383..2801)
                     /locus_tag="RD451_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDT7567391.1"
                     /translation="MLSQNAVTANTVKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            complement(3041..4609)
                     /locus_tag="RD451_002159"
     CDS             complement(3041..4609)
                     /locus_tag="RD451_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HDT7567392.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(4613..4894)
                     /locus_tag="RD451_002160"
     CDS             complement(4613..4894)
                     /locus_tag="RD451_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HDT7567393.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAAGAFSLYRVRMRKGA"
     gene            complement(4891..5814)
                     /locus_tag="RD451_002161"
     CDS             complement(4891..5814)
                     /locus_tag="RD451_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pectin esterase"
                     /protein_id="HDT7567394.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(5811..6689)
                     /locus_tag="RD451_002162"
     CDS             complement(5811..6689)
                     /locus_tag="RD451_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HDT7567395.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPTVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIETLLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(6676..8013)
                     /locus_tag="RD451_002163"
     CDS             complement(6676..8013)
                     /locus_tag="RD451_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HDT7567396.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTSAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(8016..9119)
                     /locus_tag="RD451_002164"
     CDS             complement(8016..9119)
                     /locus_tag="RD451_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HDT7567397.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(9193..10701)
                     /locus_tag="RD451_002165"
     CDS             complement(9193..10701)
                     /locus_tag="RD451_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HDT7567398.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(10667..11359)
                     /locus_tag="RD451_002166"
     CDS             complement(10667..11359)
                     /locus_tag="RD451_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HDT7567399.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(11381..12355)
                     /locus_tag="RD451_002167"
     CDS             complement(11381..12355)
                     /locus_tag="RD451_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDT7567400.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            12655..13527
                     /locus_tag="RD451_002168"
     CDS             12655..13527
                     /locus_tag="RD451_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDT7567401.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(14109..16307)
                     /locus_tag="RD451_002169"
     CDS             complement(14109..16307)
                     /locus_tag="RD451_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7567402.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEVEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLFSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            16539..17531
                     /locus_tag="RD451_002170"
     CDS             16539..17531
                     /locus_tag="RD451_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDT7567403.1"
                     /translation="MVTIKDIAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNLAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            17591..19012
                     /locus_tag="RD451_002171"
     CDS             17591..19012
                     /locus_tag="RD451_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HDT7567404.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSFPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            19005..20504
                     /locus_tag="RD451_002172"
     CDS             19005..20504
                     /locus_tag="RD451_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HDT7567405.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            20543..21937
                     /gene="uxaC"
                     /locus_tag="RD451_002173"
     CDS             20543..21937
                     /gene="uxaC"
                     /locus_tag="RD451_002173"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HDT7567406.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYLTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
BASE COUNT         6671 a         4494 c         3822 g         7041 t
ORIGIN      
        1 atcattaaaa aaaataaagg tcaagctaaa atattattta agcttgacct tattataatt
       61 tcaacgattg tcaaaagtat tgtttgcagc tgtgttgcca gtttctatag ataaatcaca
      121 gcttttgaaa cataagtttt gtactgcttc gattcgcccg aattcttttg cagttatttg
      181 gcaatgagaa aagcagacat cttctatagg cttttcagga aatgctacta aatcaaaagc
      241 tcgggaagga agtgagtaac ctggagaaag gcatgcctgt acgtttttga tgtgtatgtc
      301 tttgactttc gtcatttgct ttgattcagg tatttcttca gccactgctt gccaactttc
      361 tggcatttga gcaaggtcat tgctattttt tctattgtat tcattatgcc agtccattat
      421 ccaagaaaaa ggaaattgta catcaatcat attcagattt tctaccctga tattttcgat
      481 cactccccct ctttcttttg aagatttcat tcgaatacca cagtctgact gaaaaaaatt
      541 gatatcgtga atatatacgt cactaactcc agcactaact tcgctaccaa tagttacacc
      601 gtatcctgaa cggattttac atctagcaac ctcgattctt gatgattttc gattgactct
      661 tgcaccattg ccatctctgc cagacttaat agcaatacaa tcatcaccac aggccaaatc
      721 acattcatag acacgcacat ttgttgaaga atcaatatca atcccatctg tacttggtcc
      781 atcattgttg cggatgatta ctttttctac taatacatcg ttagaataag tgatttgcaa
      841 gttccaaaaa cctgatttct gaaaaatcaa atcacgaaca acaacatgtt ctgcatgata
      901 cagtaaacaa gcgcgtggac gtttaatagc ataatccgca atccaacgaa gtcccttttg
      961 atcgtattca gctcttgtcc cgcttttttg atcttttccc caatacagct cccaccaatg
     1021 gtctccttga ccgtcgatta ttccttttcc ttctataaga atatctttcg ccgagagaac
     1081 attcaaaatc gctgctggcc atttcatttc tacgccggct actcgtgtat cgatttctgg
     1141 aaatgcttcg atatctgttc tccccttgag gactgcacct tcttcaaaga taagatgact
     1201 cttatctttt aaaaaaaggg ctccgactaa ataaatgcct tttggaataa atacaggtaa
     1261 gtgttctttc gcaccttgat cgattgcttt ttgcagtatt attgtatcat cttgttgagt
     1321 gtcgtttgtt ttaaagttca aagcattgat aatccctttt tttgtccgca atacgtttct
     1381 ccctatcttt cattgatttt tttcaattct tcaccaataa atacagtttt tgaacgattc
     1441 agtgggtaac ctactagcaa aatgattgcg gatacaaata agcagaatgc tggtaacaag
     1501 tttgccatcg tataaatcct ttcttgtact aaaactgatt ggatggctcc acctgttgta
     1561 gacgattggt aaccaatgag tgccagcata aatccgccta ccgctcctgc acatgcttgt
     1621 cctacttttc tcgcaaaaga atttactcca tatactgttc catcttctct taagcctgtc
     1681 ttatattgat gataatcaat cacgtcagta atgaatgccc agaccatcaa attgaataaa
     1741 ccagatccta aagtagcgat aaataaaaga atcagatata cccatgcatt tgttatatga
     1801 aggaaataca tcagcaagta catacatgaa gaagcaagta acgcaaatac gcttgcttcc
     1861 tttttaccaa ataattttgt cagctttgta gcaaatggtg ctaaaactac tactgttccg
     1921 taagtaaata aaagagcaac agacattgct tgtttattat ggaagtaatc attgaataaa
     1981 taagtcatat tcgtcccagc taaaatctga ttgatcacaa tgaaaatgtc aacaatgact
     2041 aaaataatca gtgctcgatt agctaacaaa ccttttacca actgagaagc agatactttt
     2101 tcgtttttga caactcttac tctttcagta gtcaatttac aagttaacat atatgcgaca
     2161 aatgctattg cagcacatcc gattgaaatc caaaaaaaat gattccctga aacgacttgt
     2221 tgtccactct tgttatgggt atacattaaa atcggaatga agaatcctgt agttgatccg
     2281 ccaatcgcag aaccaatgct tcggaacgtg gacaacgagg tgcggtcatt aggatttgag
     2341 ctaattgctg ctgccattgc tccatacggg atattgattg ttgagagaaa aatcccataa
     2401 acaatgtatg aaacaaaaat ataagcaatc ttcaccgtca ttggaagatg ttggacgaat
     2461 ggcaaaaaca aaatgacagt cactaagcaa aatggatact tcatttttct gatccaagga
     2521 ataaatcggc cagtttctgt taactctgag acatcacata atcttccaac catcacatca
     2581 gcaaacgcat ccaaaattct cgaaatcaag aataacgtac ctacgattgc ccctgaaacg
     2641 ccaagaacat tcgtataata aatcatcaag aaactattga ctaaacctaa aataaaacag
     2701 ttacctagat caccgaacat gtagcctatc ttatcggaaa tcccaaattc ctttttttct
     2761 ttttttactg tatttgctgt aacagcattt tgtgaaagca tttgaattcc tcctacctct
     2821 tctagtaaac gttttcaaaa ttataactct ttttttcttg tttttatatt cacaatgttg
     2881 gctttttatt gcattatctt gacagataaa aaacaaaaaa taatctaaaa acattgatgc
     2941 ataagattga taactttttt tacataacaa tatatacaaa caaaaaaatt cactaactag
     3001 tgaaaataag ttagtgaacc tcatttatta aagaattaaa ttacagatga tcttttccat
     3061 catacttgaa aaactcaaaa tcagcataac ttcctctttt tttatttaga tcatgcactg
     3121 ctatcccgat aaaatttcca gtaaaccctc ctgagagtat acacatgttt ttttgcggac
     3181 ctactttctt ccattcttca gttgatacgt ctttcaaatg aaactgtgct gtctctttct
     3241 ttacagtgac tttcaaaaaa gtcttctttt ctgtgagtgg aatcgtccaa tcttctattt
     3301 gtgctactcc gttttctgat tctatcatac gtaggcattt tcccttgtcc tcattccaag
     3361 taacataaca ataaatataa ttggattcat ttaagtacag taccagtcca gccatctgat
     3421 taaaattatt aggcatgtat tcaaatgctg tctccgcatc aaaagtaaaa tccgtttgcc
     3481 gaatagctaa caaatgatgt tcgaaggtag attgaagaga ttcaccggaa atcagacgta
     3541 aaaaacctgg tctacatttt gtatcacacc aatcagcatt tggcaaaatg cgtctggcat
     3601 tccagttctt ctttagctct ccttcaaatg tatccataaa ctgatgatct ttttcttgtt
     3661 gtacctcttc atttgtctca atcattattt cttccatcgg agttgtctgg ctatctttaa
     3721 gtcttaacca atcgtcggac gtccaataca cttcttgaat agcggtttct cttcccaaaa
     3781 tagccgcacc gtttaatggt ctggtacaaa gatatgtcat gtaccatctt cctgacgggg
     3841 tttgtactaa gctcccatgt cctgtacatt gcaatgtaga agcaggtttg tcactagctg
     3901 tcagcatagg aaaaccagga tcaagctcgt aaggaccagt aatattcttt gctcggcaaa
     3961 ctgtaactga atgtcctctt cctgtaccgc cttctgccgt catcaaataa taatacccgt
     4021 tacgaaaata caaatgtggt gcctccgttt tcgctaattc tgtacctgca aatattttat
     4081 agatgggacc atcaagcttc ttcttctctg catcatattc ttgtaatacg ataccgctgg
     4141 atttattcgg tgtgtccaga cgataatccc atagttcatt gacaagccat ttttttcccg
     4201 tttcaagatc atggaacaaa gaaggatcaa agccgttact atttaaataa attggttcgg
     4261 accaaggacc tgtgatctca gatgcagtga tcaaataatt gtggacatct ttaaacggac
     4321 ggcctgcact tttgacatct gtgtaaacaa gataaaacaa tccatcagca taactgatct
     4381 gtggcgccca tatacttcca tttgtaggat ttccttgcaa agatacttga gtggtcaaaa
     4441 tatccgttgt atgtgaccag ttgactaaat ttttcgactc atatactcgg attcctggaa
     4501 gccattcaaa agaggagaca ataatgtaat accgctcttt cactcttaat atattaggat
     4561 ctggattgaa tcctcttaaa ataggatttt tcactttgat agtctgcatg attcaggctc
     4621 cttttctcat tcttactcga tataaactga atgccccagc tgctaaaaaa gcaagtgaaa
     4681 taaacaacac aacggcaaac agaccagtca tgtcctgtaa taatccaaat gtattttcta
     4741 aagacaaagt tgaatgatct acagcaagcg actgataact ttttttaaac tctgacgcag
     4801 acatattact taaagtaact gctaacccgc caaagaaaat caaagataga ctgccaccga
     4861 ccattcctag caatagttcc cattttcttt tcatttctga accccctgct tttctaaatg
     4921 tatccattca ggtcttttga tcgatgtttc ataattgtta ttacgttcag agaatttgac
     4981 agtctgttca tttttcttgt catcccaatt atcccaacca gttgggtgaa catgcccacc
     5041 tatcttacac gcttcaaata agacatttgc atacggacgc cacggtcttc ctaaatagac
     5101 gtttctagta tcaggttctg cagtcaaggt acagctttca aaacgatacc ctgttttttg
     5161 atttttcggc gtagatgctg ctgtgatgta tccaggattt ttactggcta agctatggat
     5221 atgacactga tgaaaaacgg catctgcccc accaaatatg aaatccaccg ttccttcaat
     5281 ccagcaatat tcataggtct gacgacaata ctcaggattg gcagaagccg gtgtacaaaa
     5341 aggagtacca tctttttgca aatcaggcaa cggacccgtg cataaggtat cctgataacc
     5401 agatagtcga cagtttttta aagatacgcg atctcctgaa ttgaataaag caacagcctg
     5461 tcctaccttt tctcctggac ctgctgtatt ttcgatgtga agattttcta atacgacatt
     5521 cgatccttct aagaaaaaag tagcacttcg gaaagtccct aactggctac cgtcaagata
     5581 ctcctgtttt gcaaaacgat taccggagat aactactgtt cctgctccca caagtttaaa
     5641 attggataat ctgctttcta tatattcatc atatcttcct tcttttacta tcaagacctt
     5701 tggatggcta tccggcaggc ctgccaaata atcgattcct tcttggatag tttcaaaatc
     5761 cgtcggggta tctatagcat tctttccaat tatcagtttg tctttcatcc tcataaatgc
     5821 tcccttatga attgtttcca aatatttctc atttcttgtg tttccatatg accgcctgtt
     5881 aaagaaaaag aagaaaagtt ttctggacta cccattgatt gatacttttt gtccagccct
     5941 tttctcagct tcagtacgcc ttcgtccaag cacatcgtat cgttttttcc aactaagcta
     6001 agacgagggc gcggagcgat tttttcttgg attgctaacg ttgtataagc tgtcaataga
     6061 tttggcacat agtaataaaa cccatgatga tctaggcggc gatgtagcaa aagtgtttcg
     6121 atgtccacct gtgccgctag atcaatacaa actttgacac gagaatccaa tgctgtcacc
     6181 caccagctta ataagcctcc catagaaaga ccaatcgttg cgagccgttg agtatctgtg
     6241 tcttcccttg tctccaaata atcgatcaag ctgatcacat cataaatacg cattccccat
     6301 aacgtttttc ctgttaataa aaattgtttg aacaactcgc tttcagaaat acctccgcgt
     6361 tcttcaaatc cccaagcatc aatcgaccaa acagcatatc ccattcctgt cagtacttct
     6421 gcaaaagatg gagaagctaa gtaaggagca ccatggatca attcactttt cccgactgaa
     6481 aaatctccgc cgtgagaatg caggtaaagg accgtcggaa acggtccttc tttttctgga
     6541 taagcataga gggctggtac tgtttccaat tcatttaagt acaattgata gtattcaagc
     6601 ataaaaccgt tttgtttttc tcggtataat cgttttccac taggggtatg tctgctagat
     6661 ggagcaccta aaaaatcatt caactgcata agcaaagttt ttacgaacaa ccagttcatc
     6721 catattttct gattgatttg attggaattt ctcaatactg atttctttag tattttctaa
     6781 tagaaatgct ggtccctcgt gattttcaat cgacatctgg ttaaaggaaa ccttacccgc
     6841 aaagccaata taaaatcctt gtctgctcat ttcctctatt cctgtcatca tagcaggaac
     6901 accgggaact gcatcttggg ccatcgagac atcgatattg tcaaatgtga tttcttgtat
     6961 gaattgttcc gctaatccat aaataaaacc tgcagaagca tggacattcc ttgccgtgat
     7021 attcgaaaaa tggatccttc tgaatgctga tgtccgttca tctatcggat aagccttttt
     7081 ttcccataca tacggttctt tccctcgcgg accacagaaa taataaagat tcagtataaa
     7141 tggacacatc acattatcca tgactatatt ggatactcga atatcttcaa cgatcccgcc
     7201 tcgacctcgt ctagatttca atcgtattcc tcgatcagtt tcttggaaga tacaatttga
     7261 aatggtaata ttacgaatac taccactcat ttcacttcct aatacgacac cgccatgtcc
     7321 atggaccatc gtgcaatttg tgatcgtgat attttcgcaa gcgatccttt cgtacgtatc
     7381 ttcagtccct gccttgattg caatacagtc atctcccacg tcaatatggc aattactaat
     7441 acgcacattt ttgcatgatt ctggatcaat tccgtctgta tttggtgaat ccgctgggtt
     7501 caagatcgtc aagttatcaa acgttgcatt actgcaaaga atcgggttga tcgtccaact
     7561 tggtgactgg atcaatttaa tatctttcac agtaattcga tgacagttat ggaaactcat
     7621 caatttagga cgaggataag cgagattatc tggttcattt ctaaaagtat gccaccattt
     7681 ttttccattt ccatctaatg taccgaaacc agtgacagag atgttctcta cattttgagc
     7741 atagatacag gaagcataaa cttttcgatg gactccttcc caacgtgaat gaacaacagg
     7801 ataatctttt ggatcgtcag agaatttcag aaccgctcct gcgcttaaat gaagttcgac
     7861 attgcttttt aaaaataaag ctcctgttag aaattcacct gctggaacaa ctacggtccc
     7921 gcctccgtca cttgctgcag catcaatggc ttgttgtatt gcttcagtat tcaattcatc
     7981 aattgatgcg ccaaatgtca aaatatcata catatttata atgcctccac ttcaatcaat
     8041 gcttgcaaga atgcaccaac gcctttttga tcattacaaa taattggttc actgatgtag
     8101 taagcatatg aaccatctcg ctgatctgct ccgcctaacc ctgctacttg acagttttta
     8161 ttcaagttca gccagccttc ttttgtttcc agaacaaatt catcaagtaa tccttgatgt
     8221 gatttcttca cttgtggaag ccattcttct ttgttcagca gtcccaaacg tattccttta
     8281 gccattgcgt aaacaaacat actactgccg gaagcttcca gataatttcc tttccgtttt
     8341 gtttctgttg ttacttgata ccatgtcccg ctgttttctt cttgatatgg aagtaatgca
     8401 gccagtgtct tttctagaat ttctttcagc aaagaacaat ctgtttcttc atgaagtaat
     8461 tcataggtat ctgctgcagc catcaaatac cagccaatcg atcggctcca aaaatgatgg
     8521 gatagacctg tttttggatc agcccatggt tggaccttct tttcatccca tgcatgaatc
     8581 agcaaatttg tttttggatc gaatagatgt ttataactga tttcaaactg tctcaaaaca
     8641 tcttggtaat ctttttcttc actaaaattc tggataaatt cagcataaaa aggagaaccc
     8701 atatataagc catccaacca aatttgataa ggataaattt ctttatgcca aaaagctcct
     8761 tcggatgtgc gtggatggtt tgccaactgc tgggaaagga gttctgctgc ttttttatat
     8821 ttttcttcgc ctgtttcttt gtacaataaa aagaaaagct ttcctgtatt tacatggtcg
     8881 atattgtatt cttcaacgct gtagccacgg atcgttccat cttcttgcac gaaatagtcg
     8941 atattgtctt ttatgaaatc aaaataaatt ttttcttggg ttcgttccca aagtaattgg
     9001 aaccctttaa gtacgacgcc atagtcataa gaccattttc ctttatacca cttttcttca
     9061 tataagcgag gtgttctttc catgatactt tttgctaatt tctttgacca gttttccatt
     9121 atttgctctc ctttaaaaat taaaatagga tttgggacaa ataccaagaa gtatttgtcc
     9181 caatcgtcta tattactgtg ccgctgcttt gtatgcttcc tcgtactctt gtgtgattcg
     9241 atcgcctcct tgtgctttcc agtcttctac agcttttttg aatccatctt cgtcaagctg
     9301 tcccatgatg tattgcaccg tagcatcaat gacgattttt tcaatttctg atcctacttc
     9361 attgttcgtc ggtgaatcca atggcacaga aggatccatt acagcaaatt cttcattttc
     9421 tttgatcaat tgattagaga attctttttc agggtctgta tctttgaaag agaacgtcac
     9481 ttcactagga cgagagcttg ataacggttg cacctcttgt tgccaaagat ccatatcgat
     9541 aaattcgata gaaccatcat cattcaattc ataatgcgtt ccttcgatac cgccagtcat
     9601 caatttatac acatcttctt ctaaaagatc atcaacaaat tgaagtaatt tcttcaattg
     9661 tgcttcgtct tttacttgag atttgggaaa tgctagcaag ccgccaatac catttccttc
     9721 tgaccaaaca tgataaccgc cgccttcacc atctgagatc ttgtttacag gcactaattc
     9781 catatcatct tgaatacctt gacccatcgt cttcagattc ttgatatcca ccattccagt
     9841 gtagattcca gttcttcctt gtgcaaattg ttcttgctga tcagtctttt gggtaactgc
     9901 aaagtcttgt gccaaatagc cattctcaaa tagatctctt gaaaaattca aagctttcat
     9961 atactcttct gtatcaaatt ctggagtgaa tttgccatta tcgtctacag cccagccatt
    10021 tggtgctcca aaataagaag tgaaaagttt aaagctggta taacgaatat cactaggcgc
    10081 acgatcgcca aaaccaactg tgtcgtccac accatttcca tcaggatcgt tttctgtaaa
    10141 ttgtttagct acttcataaa gctcatccat ggtagttgga acatctagtc ctagattatc
    10201 caaccagtct tttcgaatga ctaagccagc acgagcgtag tctttttgta tcggtacgcc
    10261 gtacaaggca ccgtcgatac tcgcagcttc gattctatct tcagaaattt gacttaaatt
    10321 tttatagtct tttaaatatt ctgatacatc ccagaatacg cctgatttta acgcattgcg
    10381 gacagaagag tttttcaaca tcgcaatttg aagtgtaacg atatctccta gttcatcaga
    10441 agccaatgca gttgttaatc tttcttcttt tgaagcatca ggaatccagt tgaatgtcag
    10501 ttccgtatcg gttttttctt cgatcaagtt cacaatcgtg tctgtaggcg gtgaagcatg
    10561 atgcaaaata tttaaccaag tgattttagc ttttccatct tctgtctctg aagaactgtt
    10621 acttgaactg ctgccgcatg cggcaagtgc tagaattcct gcaaaactaa gacctaattt
    10681 tacgagcgtt gcttttttca taaattttct ccttcactgt tttaataata tttttgtttt
    10741 cttctgtttt ttctgtatat gagttcttcc attccaaatg gcaaaatata gaatttgctg
    10801 tccacgtgac tgcggaaaag aagagactgc caccgataaa ggttaaaaca cctggcattg
    10861 tttggatgat catcagataa atccctacca tacttaatat caacactaat gagtaatgaa
    10921 gatgtgagaa tccgaataaa aatgccattt tcattttgaa aaaatatcct ttccaatcat
    10981 aatgagccat gattgggaaa atatagagtg ctgagagcac atatatgaac gcagcaatat
    11041 acaaagcgat cctaagatac caattgtgta tgaaagaaag atccacaagt aaaacaatcc
    11101 cgatggcgcc atatatccag ctcatcagca aggtttcacg atagttttct ttaaaatatg
    11161 tgaagtacgt tttcgtcaaa ggaaacgttt cttttgagcg cagccatttt ctaatcactg
    11221 caaccatcgc atacgatgca ggaccgaaag taaaaactcc caaacctgcg atgactaaac
    11281 cgccccacag aaaattcaaa taaaccaact gtaaaatacg atttagcctt ccgtttattt
    11341 tatctaatga ctgcagcata tctttccctc tctttctatc ttagtaaacg ccgtcttctc
    11401 ctagcttttt ggcaatctta ttagctaaaa ttaccataaa caatcctacg acccctttaa
    11461 acaatcccat tgctgtactg aaacttaact gtccattctt caatccagct gtataaatat
    11521 aggtgtcgaa aatttctgca acgcttcgat tcaatgaatt caataacaag tacatatgct
    11581 cgaaccctaa gtctaatgtc tgaccgattt ttagaatcag caaggtaatg attactggac
    11641 gaattgccgg caatgtaaca tgccatgttt tgcgtaagcg tcctgctcca tccatttctg
    11701 cagcttcata caactgtgta tcgactgcag ttatcgctga aaggtagatg atcgtagacc
    11761 agcccaactc tttccagatc acttgtccga tatatactgt gcgtgtccat tcaggggatg
    11821 ttagaaaact gattttttca aatcccattg ttgcaaggaa ttcattcaat acccctccgt
    11881 caacattcaa aaatacataa gtaatcgaaa caatgattac ccaagacatg aagtgaggga
    11941 tgtaaatgat cgtttgaatc ccgtttttca atcgtttgtt cgttacttca tttaatagta
    12001 aagacaaaat gattggcatc ggaaaaaaca cgaagatatt taatccgaac aagatcaacg
    12061 tatttcttaa taatgtaaag aatgtcggtt ctgtaaacaa acgaatgaaa tgtttgaaac
    12121 cgacccaagg acttcccatt attcctaaaa atggttgata atcttgaaaa gcaataacga
    12181 gtccccccat aggaagatac ctaaaaatca agaaataaag gactcccggc agaatcatca
    12241 catataaaaa tttattcgtt ttgattcctg caattatttt ttttcgtctt ctgagctttt
    12301 cttctttttt cgatagcgtc agttgaaatg gttcttgttt ctttacactt tccataagcc
    12361 cctccttagt tttgtgaatg tttgctgctt atgacttcat gatagataac tatctgaatt
    12421 acgtatataa tcatttttat cgtaagtaaa aacgcttaca tagcaatgat ttttgtgcta
    12481 tacaaaacga taaagtgtat tttttcacaa ataaactacg catagcaaac cttctatttt
    12541 tttctatctg acacttagca taggaaatga ttatatacgt aatctttcac cgatgataaa
    12601 ttgaacatat agaaacagaa acatttaatt tattttgagg aggagcctat ctatatgaaa
    12661 aagaaagtct ctataggaga aagaagtttt acacttttca acaatacgtt tctaattttg
    12721 ctagctttga tctgtatcgt tcctttttta aatatcatcg ctacatcttt tgcttctaca
    12781 caagaagtcg tcgcgaaaaa gtttatcctt tttcctacta ccttttcttt agacgcgtat
    12841 cgctacattc tttctacgcc gaccattttt agagcacttg ctgtttcgat tggtgttaca
    12901 ggtgtcggaa cgatcgtcag tatgtgtgca acttcactga tggcctacgg tctttccaga
    12961 aagtatttgt ttggtcgagg tttcgtcaac tttcttgttg tattttctat gttgttcagc
    13021 ggggggatga ttccaacgtt cttagttgtt cgttctctag ggctggtcaa ttcttactgg
    13081 gccatgatcc tgcctgtggc tgttaatgca atgaatatga tcattatgag aaactttttc
    13141 caagccttgc cggatagttt ggaagaatca gcaaaaatgg atggttgcac agattttggt
    13201 gtatttttca aaattatgct gccattagct ttaccgtcta ttgctactat ctcgcttttt
    13261 tatgctgtta cttactggaa cacttatatg actgctattt tgtatatcaa cgattcatct
    13321 aaatggccga tacagattct tttacgccaa atcgtcattg tatcaagtgg gatgcaagca
    13381 gaaagtagtg ccgttgatgt gattccacca gcacaaacag ttaaaatggc tgttatcgtt
    13441 attgcaacag tgcctatgct gattgtttat ccttttgttc agaaatattt tgtcaaagga
    13501 gcactcgtag gttctgtcaa agggtgatta tgtactgaac gcaaaatggt agttgtgtca
    13561 gaagtggtca gcttcaagaa ataagaaggc atttacgaaa attgcttctt aaatttttgt
    13621 gaaatttcgg cttatttttc gaagaatcta ctcctggaac accgtgtatc agaggttgtg
    13681 aaagagacgt tcagccttga gcgatgataa aaactctcac aaacattgcg acgagtaacc
    13741 cacaggagca ataagaagcg attttgaaaa atagcttccc atatttcaca aaattatgcc
    13801 ttattgtcga tagcctgtct cttgaacgcc atttattcgt aaaaaagaac tgtgacaaga
    13861 cttttgtcac agttcttttt gcgtgcttag ccttgaaatt taactatcca taaatacaaa
    13921 tactagggtt attctaactt cttttattgc ttgaatcagt ccacaagaaa aacagcctct
    13981 tgattaaacg gcgtttatct tgttgattct gcggcaataa aatcagccag cagcaaaaca
    14041 tgaagtgctg ttttttgctg tcctctttta ttgcttgaat cagatcacaa gaaaaacagc
    14101 ctcttgattc acaaatattt ttttcgatat tctcccggcg taatcgattc cttcttttta
    14161 aagaaacgaa taaaattttg cggatttcga tattgcaatc tttctgcaat ctcttttacg
    14221 gagaggttag tctctttcaa ccattttttt gctacctcta aacgatgatt ttgaacaaaa
    14281 tcaccaaatt tttctcctgt ttccttttta aatacattac ttaaatagtt agggttataa
    14341 tgcaacctat cagcgatcac atctaaagac agatcacgat catattctgt gtagacgata
    14401 tgcataatat tctccgacaa atttttaaat tcatgatcag tgattgcttg agagcattct
    14461 gtgattggca gaactaattg ttctaaaaca agtttttcta gttctttggg atgataattg
    14521 ttcagtgctt ttacataaat ttgtttcatg ttatcaaagt tttttgaatc tactcccaat
    14581 aactgtccta attgaacgag ttcattgatc aagcggaccg aaactacttc ccgactcaaa
    14641 ggatttttat tttgtgcaaa caatgcatca atcaattcat gtactaaatt cttcacttcc
    14701 tgatttccag aacgaatggc ttcaaacaat cgattttgtt cttctatcgg atatctaata
    14761 agtgtttttt catgagcagc aggaacgatt tcctgataaa aaataattga acttggacca
    14821 gtatttacac gataatacag ggcttctttt gcccgatcaa ccgattgctt gctttcattc
    14881 agcgtttcga accggttact gatgcctata ctgatagtta aattcaagta ttcttttaca
    14941 cgtttttgaa tgagtcggca atactccatg acttttttgc ttgcttctgc atcatcttta
    15001 tccattcgat aaatagtggc ttgcatttct tcattcaaaa cgatcggcag cattcgattt
    15061 tcctttggca caatttccgt gatcatgttg ttgatcgcta aaagtagcaa atcacgctcc
    15121 ccaccgtgac tatcttctaa cagatcgatt tgaaccaaag ctgtataata gcagtcattt
    15181 tgagaactat aaccaaattg ctgcaaccgc tgatctagtt ctcgcctttc tactcgattt
    15241 ctaaataaac taagtacaaa tagcgtttcc agctgtggct tttgggtaac taagtgtgca
    15301 cttaacgctt ctttttctcc tatgatccga ctgactgatt gagcgaccaa atctagttct
    15361 ttcccactga atccttttga tttaagattc agacgttcct gtatttgaga aatcggacgg
    15421 gcaaatctgt ccgaaaataa gtaggaaaaa agaccaatga gtcctaccag tgttaaagac
    15481 actgcaacta gcccgattct cagattgcgg atcattgcgc caattgcact agagtcaact
    15541 tctaatctgt aaatccaatt attataatct gatttcagta ctatatacgt tttatctttt
    15601 tctcttatca ctttcagctg attgtaatct agatccacgt ccgttaatac agttggttgc
    15661 tctttatttt ttactgtctg agtagtaaaa aggttgccaa cttcgttttc aatagaaagt
    15721 atgtcttctc cactttcacc aacaacttgt tctattgtat gtttctctat cgtagcaatt
    15781 cccaatgcat atttttcttt ttcaaacatt ggcaaagaaa tcaccatttc gattcctttg
    15841 tttttctttt gccaaaataa attatttttg ttatttatgt acttctgttg atacttttca
    15901 acttcctctt cggtcagttg actcaacgat ccattgatta ctccccattt accagccaaa
    15961 ctgactaaat cataattatt atcatccata acaatcgttt ctataaaatt tagttctttc
    16021 ctgatttcag aataagtgga gtaatctgta tatgtcagcg gatgcttgaa tatgtccgag
    16081 aaatttttgg tcgaaccata cgtagaaaac gaatattcaa tcgttctaat tttccattca
    16141 acgttagttt taacttgcct gagcaaattc tttttgtctg ttaaataact cgattcgatc
    16201 gattcatagg tattctggta aatgaataaa ctaaatccta tgacaagtac ggctcctaat
    16261 aaaaacatcg gtaaaaatat tttataaaat actgtacttt tcttcatttt cttcctctcc
    16321 tccttttaaa ataaaaggct ttcatttttc tgtaaaattg atactcatct aattaaatga
    16381 gcattccccg ctttcaagaa tagcataatt aaaaataaaa atccaagtaa tttttaacgt
    16441 gtgcaatctt ttcatatcaa agatctattg acttatcgta gttatcgtaa tatgatgaat
    16501 gcgttaacaa aaagtgaaaa agtaaggaaa atgatggaat ggtaacgatc aaagatatcg
    16561 ctaaagcagc tggcgtttct catacgacag tttctcgtgc tttgaataac agcagtttaa
    16621 taaaaaatga aacaaaacaa aaaatacgac aactagctaa ggaaatgaat tattcgccaa
    16681 actatagtgc aaaaggttta gtgaatcaaa aaaaatatct aatcggacta tttttctcaa
    16741 gtttgcataa aggaacttca tcaaatttcc tagcagattc cattgcaggc atccattcag
    16801 tattagacac aaattacagt ttatctgttg aaagtatcga tgttgttgat ttaacagaaa
    16861 tcaacctgca acgctacgat ggactgatcg ttatgagtca aagtgatgat gatcagcctt
    16921 tcatcgacta tctcaaagaa aaagaatttc ctttcgttgt tgtcaatcgt cacatcaatg
    16981 atccagcggt tatcaacgtc actgccgatg atgcggccgg tgttatgcag gcagtagatt
    17041 acggtattgg atgcggacat acgaagatcg cttatattgg cggaaagaaa aattttcgtt
    17101 cgacaaaaga acgggaaaaa ggggtattga aaagtctaaa aaaagcgagc atccctgtca
    17161 atctagccta ttttttaaca ggagattaca gcttagaaag cggcctccaa aacatggaat
    17221 acctattatc actttctgac ctgcctactc tggttttttg cggcaacgac gacatagcga
    17281 ttggtgcatt gagagctgta catttagctg gcctccgtgt tccccagaac atttctctga
    17341 tcgggttcga tgattctcca gtcgtctcct atctcaatcc gccgcttacc accgtacgta
    17401 agcctttgaa agaaatgtgt caagaaggaa caaagctttt actagatttg atcgaaggca
    17461 ggacgatcga acaatctaaa attgagctct ccaccttgtt gatccttcgt gagtcgatca
    17521 attacttgta aactacaagt aattttatat aaaaatgtta acgtgtgcat aacacagaaa
    17581 ggaagtttat atgaaaaaac tgacaaaaga attagtgaaa aaaaacgaag cacctgtaaa
    17641 agttcttcag tttggtgaag gcaattttat gcgtggattt attgattggc agattcagca
    17701 gctgaataac caacaattgt ttaaaggtaa tgttgcaatc attcaacctt tagaacaagg
    17761 tcttggaaat atgatgaacc agcaagataa tttatatacg gtcattttac aaggactcag
    17821 caatggcgaa atcgttgata cttccgagat tatcaccgta gtagaacaaa tgatcaatcc
    17881 ttatgatgaa tgggatgctt atctatctct agcagaaaat gacgacttgg cctatatcgt
    17941 ctccaataca acagaggcag gaatccaatt cgtggagact gataatttaa cagatactcc
    18001 cccacagagc ttcccgggca aactgacagc ctttttatac cgacgtttca aattaaacaa
    18061 agctggcttt accatcattc cttgcgaact gattgacaga aacggcgaac gtctaaaaga
    18121 aatcatttta cgctacgcag aaaaatggga tttagaacct gcttttgttg agtggttaga
    18181 aaaagaaaat gttttctgtt gtagtttagt tgatcgcatc gtcccaggtt atcctcgcga
    18241 agatgcaggt gttttcaatc aacggcataa ctatgaagat caattgatgg tcaaagcaga
    18301 accattcatg ctttgggtga tcgaagggcc taaagaattg gagaatcaac taccattcaa
    18361 acaggctggc ttgaatgtca tcatcacaga tgatatgact ccttatcgtg aacgtaaggt
    18421 gcatttgctt aatggaccgc atacagcgat ggtccctctt gctttgttgg cggaattgga
    18481 aactgtagaa gaagtaatga aagatccttt attctccgca tatgttgatc agttattcaa
    18541 tctagaattg attcctatgc tttctttacc taaagatgaa ttagccattt atgctgacca
    18601 aatcaaagaa cgtttcttga atccttttgc ccatcacaaa ttagaagcga tttcattaaa
    18661 tagtgtttca aagttcagca cccgtctgct tccagtgttc aagaagtata tcgaagaaca
    18721 aaatcaggta ccaccgttaa tcactgtttc actagctgcg ctacttctta tgtatcgagg
    18781 cgatcaagta aagccacatg atgatgaaaa gacgataagc gaatttactg atgcttggtc
    18841 tgataatgga acagctattc ctcgattatt gcaaaacgct gcgctttggg gagaagattt
    18901 gtctcaaata ccgaatgtga cagatacagt tcaagaaata gctgcaaaga tcgatcaaaa
    18961 aggtgtccgg tcagtattac aagaaatgaa aggaacgatg gtccatgctt gaaaccctgc
    19021 aaccaacaat gaaattaaat cgacgagaca gtgtggtcgt cgcattaacc cctattccaa
    19081 aacaaacaca actgacgatt gatcagcaaa cgatcaccac tcttgaagat atcccgcaag
    19141 gtcataagat tgcattgggt gatttgaaag ctggagacaa cgtgatcaaa tatggctatc
    19201 caatcggtca tgtgacgaca gacgtaactg ccggtcaatg gctgcacact cataatgtaa
    19261 aaaccaatct ttctggtgaa ttggattatc gatatgaaaa agatgtccat ccaagtcatt
    19321 acctttttga gaaccgaaca tttcaaggtt acttgcgaaa aaatggaaaa gtagggattc
    19381 gtaatgattt gtttttagta cctaccgttg ggtgtgtgaa tggcattgct gaactgatcg
    19441 tcaaacagtt caaggaaaaa catccagatc tgggacagtt tgaccatatt acgattttaa
    19501 agcatcctta tggctgttcg cagcttggaa aagatcatca aaatactcga gaaattttag
    19561 cggacgcagt aaatcatccc aatgccggag gagttttagt atttggatta ggttgtgaga
    19621 acaatacagt tcctgaattc aaaaaaattt taggtgaata tgatgaagaa cgagtgaaat
    19681 ttctagtggc tcaagatgtt tacgatgaga tcgaacaagg tgtggctcta ttagaagagc
    19741 ttttaacagc ggcggaaaat gaccagcgca tatcagtccc gctctctaag ttgaatgtcg
    19801 gtttgaaatg cggcggttct gatggtctat cgggaataac tgctaatcct ttacttggtg
    19861 cattttctga ctacttgatt gctcaaggag gcagcacgat cttaacagaa gtgccagaaa
    19921 tgtttggcgc agaacaagta ttgatggcac gagcggaaaa tgaagaagtt tttgactcaa
    19981 tcgttgactt gatcaatgac ttcaaacagt atttcttgtc ttacggggaa ccagtttacg
    20041 aaaacccatc tcctggtaat aaagcaggtg ggatcactac attagaagat aagtctttag
    20101 gctgcacgca aaaatcagga agctctcctg tcgttgatgt gctacaatat ggcgaaaaaa
    20161 tcagaaaacc agggcttagt ttattgcaag ctcccgggaa tgatcttgta gctgcctctg
    20221 ctcttgcttc atccgattgc cagttggtct tgtttaccac aggaagaggg actccgtttg
    20281 gctcatatgt cccaacggtc aaggtatcta cgaatacaac tctttttgaa cgcaaaggtc
    20341 attggatgga ttttaatgca ggcgtcttat tagaacaacc aatggaagta atcttagaat
    20401 cgtttgttca aaaaatcatc gctgtagcta gtggagaaga aacgaaaaat gaacaaaatg
    20461 acgttcgaga aattgccatt tttaaaaacg gagtaacact ttgattttca taaaacagta
    20521 taaaaagaaa gaaggaagat ttatgttttt atctgatgat tttttattaa aagacgattg
    20581 ggcgaaaaag ctttaccatt cctacgcaaa aaacatgccc attattgatt atcactgtca
    20641 cttagatcca aaagaaattt acgaaaacaa caatttcagc aatctgacag aagcttggtt
    20701 aggaggcgat cattacaaat ggcgcttgat gcgagcttgc ggcgtgcctg aagaaaaaat
    20761 cacaggaaat gcttctgatt ttgaaaaatt tttagcttgg tgtcaaaccg taccaaaaat
    20821 tatcggaaat ccgctttaca gttggtcaca tcttgaattg aagcgtttct tcggtattga
    20881 cttgttgata aatgaagaaa atgcagagaa aatttggaca caagcaaatg aaattttggc
    20941 agctcctgat tttcgccgtc gggaaatcgc aaaaaaatcg aatgtagaag tgatttgtac
    21001 aacagatgat cccgcagacg acttgcacta tcatcagttg cttgctcatg aagaaccaga
    21061 tttgaaggtt ctaccttcat tccgtccaga taaagcactc aatattgaaa aagaaggatt
    21121 taatgcatgg gtcacactac tggaagaagc agctgaccaa acgatcacca cctatcaaga
    21181 actgatagaa gtcttagggc agcggataga atacttccat caacatggat gtcgtgtttc
    21241 cgaccacgct ttagacatct tacgctataa agaagcggat gaaacagtat tagaagagat
    21301 ttttcaaaaa gcacgagcta acaaactatt atcttcagat gaaatcgatg cttatcttac
    21361 agaaacactg atacatttga cccacttcta tcattctcat aattggacga tgcagctgca
    21421 catccatgct tatcgtaact gtaatacaca aatgttggaa aaattagggc ccgataccgg
    21481 ctatgatgga atgaatgatc tttctttgac tattcctctg caaaaattat tgaaccgtgc
    21541 agaagaaacg gatcagttgc caaagacgat cctttattca ttgaatccga atgactatcc
    21601 tgcgatttta gctttgatgg gctgtttcca aaaagaacag aatggaaaac tgcagttagg
    21661 ttctggatgg tggtacaacg atactcgagc tggtatgcgc gatcaattga cacaatttgc
    21721 tgatggtagt gctttgggga attttgtcgg catgctgaca gattcaagaa gtttcctgtc
    21781 ctacactaga catgaatatt tccgtcgtgt tctttgtgaa tttttaggcg aaatggtcat
    21841 gcgaggagaa gcacctgaag atgaacaact tttaggaagt ctagttcaag cgattagtta
    21901 tacaaatgct aaaaattact ttggcttttt tgcctaattg attaatagta acagtaacga
    21961 atcaaaaaca ggatagtgaa ataacggaat ccgtttatcc acgttttaga gaagaagacg
    22021 gaccaaat
//
LOCUS       DAPBAF010000047        21958 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.047, whole genome shotgun sequence.
ACCESSION   DAPBAF010000047 DAPBAF010000000
VERSION     DAPBAF010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 21958)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21958)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21958
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.047"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(133..306)
                     /locus_tag="RD451_002174"
     CDS             complement(133..306)
                     /locus_tag="RD451_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDT7567407.1"
                     /translation="MIFLLTVNGPTNSNFYGAGSTDLLVTWLYLTVTKIDYNLASVIG
                     ILIFIYMQKFIYY"
     gene            754..3116
                     /locus_tag="RD451_002175"
                     /pseudo
     CDS             754..3116
                     /locus_tag="RD451_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase family protein"
     gene            3484..4407
                     /gene="truB"
                     /locus_tag="RD451_002176"
     CDS             3484..4407
                     /gene="truB"
                     /locus_tag="RD451_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HDT7567408.1"
                     /translation="MDGLLPLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEKKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVERFKRVDITDEVWQKVKNGMRLDYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            4411..5352
                     /gene="ribF"
                     /locus_tag="RD451_002177"
     CDS             4411..5352
                     /gene="ribF"
                     /locus_tag="RD451_002177"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HDT7567409.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGETWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            5704..6489
                     /locus_tag="RD451_002178"
     CDS             5704..6489
                     /locus_tag="RD451_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDT7567410.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWVNNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENNKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            6502..7353
                     /locus_tag="RD451_002179"
     CDS             6502..7353
                     /locus_tag="RD451_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transporter"
                     /protein_id="HDT7567411.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(7477..7929)
                     /locus_tag="RD451_002180"
     CDS             complement(7477..7929)
                     /locus_tag="RD451_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7567412.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQFREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNYVVNFSQWINEKLLIQTDISLVS"
     gene            complement(8394..8762)
                     /locus_tag="RD451_002181"
     CDS             complement(8394..8762)
                     /locus_tag="RD451_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1801 domain-containing protein"
                     /protein_id="HDT7567413.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            8912..9394
                     /locus_tag="RD451_002182"
     CDS             8912..9394
                     /locus_tag="RD451_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA editing protein"
                     /protein_id="HDT7567414.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            9431..10441
                     /locus_tag="RD451_002183"
     CDS             9431..10441
                     /locus_tag="RD451_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HDT7567415.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPTWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQSSEKYQKVWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTIRHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(10556..11269)
                     /locus_tag="RD451_002184"
     CDS             complement(10556..11269)
                     /locus_tag="RD451_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567416.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIRQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLIDVTVIDN"
     gene            complement(11459..12049)
                     /locus_tag="RD451_002185"
     CDS             complement(11459..12049)
                     /locus_tag="RD451_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HDT7567417.1"
                     /translation="MKTAITFLLEEYADWEGAYITSTLNQNEKWQNKTASIQSEVTSI
                     GGLKTKIDYLIEQIPEKVDLFIMIGGNSWDIKNHHLYQIIDKLLKTDVPVAAICGAVD
                     YLAQSGLLQGYKHTGNAQFPWLESENYQNKEDFIEQQAVKDRNLITANGTAPIEFTDL
                     ILQAVHFETEEIREKTIRLYKLGFYDYYKKYGDPFS"
     gene            12533..12760
                     /locus_tag="RD451_002186"
     CDS             12533..12760
                     /locus_tag="RD451_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HDT7567418.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            12776..13941
                     /locus_tag="RD451_002187"
                     /pseudo
     CDS             12776..13941
                     /locus_tag="RD451_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
     gene            14175..15218
                     /gene="hrcA"
                     /locus_tag="RD451_002188"
     CDS             14175..15218
                     /gene="hrcA"
                     /locus_tag="RD451_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HDT7567419.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEDKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            15312..15875
                     /gene="grpE"
                     /locus_tag="RD451_002189"
     CDS             15312..15875
                     /gene="grpE"
                     /locus_tag="RD451_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HDT7567420.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            15926..17755
                     /gene="dnaK"
                     /locus_tag="RD451_002190"
     CDS             15926..17755
                     /gene="dnaK"
                     /locus_tag="RD451_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HDT7567421.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            17906..19072
                     /gene="dnaJ"
                     /locus_tag="RD451_002191"
     CDS             17906..19072
                     /gene="dnaJ"
                     /locus_tag="RD451_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HDT7567422.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(19154..19819)
                     /locus_tag="RD451_002192"
     CDS             complement(19154..19819)
                     /locus_tag="RD451_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7567423.1"
                     /translation="MELDFSSPYYVVVGQLSDNQQLCQERINPLLELLERVFSYYGQA
                     LLTVHRQQIIILVNRISRASLLSLLDKIQTKFNKMYQLQLNFGIGSLCYTEQETPQSF
                     LHAKQVCEWIAFHQSVNEIRFFEDLDLGIVLPAIPSDQRTLYVKRILKSLTEEEVHLF
                     KKTLACFSKNNGSIKNCSEELFIHKNTLQYRLNKFHSLTGYTPRNYDDYHILKLAFLL
                     VQT"
     gene            19795..19968
                     /locus_tag="RD451_002193"
     CDS             19795..19968
                     /locus_tag="RD451_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567424.1"
                     /translation="MEKKNQAQLSEGGIDYVLDIINEPMVLSYAMEQVERLLVCAGKQ
                     AMRLIRLGEKIRR"
     gene            complement(20196..20402)
                     /locus_tag="RD451_002194"
     CDS             complement(20196..20402)
                     /locus_tag="RD451_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018596002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7567425.1"
                     /translation="MICKASSGDEMAVKEILKFYDGYISKLCLRPFYHSESGKIIMQV
                     DEELKGEIHTDMMKAILKFEIGVK"
     gene            complement(20428..20847)
                     /locus_tag="RD451_002195"
     CDS             complement(20428..20847)
                     /locus_tag="RD451_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009588541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDT7567426.1"
                     /translation="MRTSSFEHIVRLQFNSLMLIVIKNKVKSRNRQLARHSKREVLFC
                     EIAETKQVERGTIDTCFYDCVSFKVLHFTIYVSDETLGTVLHRLSEKQRSAILLRYFQ
                     GMNDREISELYHVSRSAICSRRTRGLRKLKMLLSERK"
     gene            21351..21704
                     /locus_tag="RD451_002196"
     CDS             21351..21704
                     /locus_tag="RD451_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7567427.1"
                     /translation="MRKKEDKYDFRAFGLAIKEARLKRGLTREQVGALIEIDPRYLTN
                     IENKGQHPSIQVLYDLVSLLHVSVDEFFLPANNLVKSTRRLQIEKYMDSFTDKELSLM
                     ESLASGINEARNIED"
     gene            complement(21764..21931)
                     /locus_tag="RD451_002197"
     CDS             complement(21764..21931)
                     /locus_tag="RD451_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HDT7567428.1"
                     /translation="MCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIKQFKVTV
                     ITEPDAKTQSR"
BASE COUNT         7387 a         3745 c         4510 g         6316 t
ORIGIN      
        1 aaatcagggg ttgcgggatt tttttgtttt cattaagacg tattacctaa gagttccatg
       61 actttagtct tgcggcgtgt cagctaacca aaaaagagaa aaagaaaagt aaaaaattcg
      121 actttctttt ttctagtagt atataaattt ttgcatatag ataaagatca agataccgat
      181 aacggaagct agattgtaat ctattttagt gacagtcagg tatagccaag taactagaag
      241 atcagtggaa cctgcaccat aaaagtttga gtttgtcggt ccgttgacag ttaaaagaaa
      301 aatcacgttg aagttattga tatttccgat tacgccgctt cgatttggtc acgatccaaa
      361 ttttggataa tccctgtaga aattagcata gtagctggga taccaattca catattgaca
      421 aagataacag agacttttac ataaaacgga tcaatcagga aaggaattgc tcgatccagc
      481 cccagttttc cagcaatgtg ttaactggcc cagcgtcatt cagcaaatta tgcatgatga
      541 ggagcgaaat gaactgcgga acagccattg tgataacgac aagttttttg gatcaatgta
      601 aaaaacgtca gcgaaaggaa aaatttcgtg gttttttata cctgttcatt tggctagata
      661 taaaatccaa acaaatgaac agaagtgctt attaggtttc aattgggagt atctgcgcta
      721 gaataagagt aataatgaaa aggagtgtta tgtatggatt attctagtaa agaatacttt
      781 gataaaatga cggcttggtg gcgtgctgct aattatcttt ctgttgggca actttatctt
      841 aaagataacc ccttactgag acgtacactg aaacccgaag atgtcaaaaa acatccaatc
      901 ggtcattggg gaacgattcc tggccaaaat tttatttatg tccatttgaa ccgagtcatc
      961 aataaatatg atttgaacat gttttatatt gaagggccag gacacggcgg acaagtcatg
     1021 gtatcgaatg cttatttaga tggaagttac acagagatct atccagaagt aacggaagat
     1081 gagacaggaa tgcaaaaatt attcaaacga ttttcatttc ctggaggcat tgcttctcat
     1141 gcagcaccag aaacaccagg ttctatccat gaaggcggag agcttggata ctctctttca
     1201 catgcagtcg gagctgtatt agacaatcct gaagtaatct ctgctgtcgt gattggtgat
     1261 ggtgaagcag aaaccggtcc tttagctgga agctggttct caaatgtctt tatcaatcca
     1321 gtgatagatg gagctgtttt accgatcctt catttaaatg gtgcaaaaat agccaaccca
     1381 acgatcttgg cacgtaaatc agatggagaa ttagcaaatt actttaacgg acttggctgg
     1441 gaacctttct ttattgaagg aaatgattca gaaaaattaa atcctgttat ggctgaaaaa
     1501 atggatcaag caatcgagaa aattaaatcc atccaaaaag aagctcgcct gaagacagca
     1561 acagatgtcg tgatgccaaa atggccagta ttgatcgtac gcacaccaaa aggatggacc
     1621 ggtccaaaag aatgggacgg ggaaccaatt gaaggaacct tccgagcaca ccaagtaccg
     1681 attcctgtag atcaagaaca tatggatcat gcagatgctt tactccgttg gctgaaatcc
     1741 tatgaaccag aaaaattatt tgatgcacaa ggacgtattt tagaagaaat cagagaaatc
     1801 gcgcctactg gtgaccaaag aatggcaaaa aatcctatca ccaatggtgg aatcgatcca
     1861 agaccgctta ttatgccaga ttggaaaaaa tatactttgc aatttgaaaa accaggctcc
     1921 gttaaagcag aagatatgac cgaacttggt aaattcgttc gcgagatcat tgagaaaaat
     1981 ccagaaaatt tccgtatatt tggaccagat gaaacaaaat caaaccgatt gaatcaagtt
     2041 ttcaaaacga caaatcgcca atggatggaa aaaatcgaac cagaaaatga tgaatggctt
     2101 tcgccatctg gtcgcgtcat cgacagtcaa ttatcggaac accaagatga agggttctta
     2161 gaagggtacg ttctgactgg acggcatggt tttttgcaag ttacgaatca ttcttgcgag
     2221 tggttgactc tatgttgact cagcacttca aatggatgcg gaaatcacat gacctttctt
     2281 ggcgaaatga ttatccttcg ctaaatctca ttgcaagctc aacagtcttc cagcaagatc
     2341 acaatggata tagccaccaa gatccaggaa tattgacaca tttggcagaa aagaaggcgg
     2401 agttcatccg tgaatatctg cctgcggatg caaatacatt gctcgcagtc atggataaag
     2461 cattccgctc gtcagaaaaa atcaatttga tcatctcttc caaacatccg cgtgctcaat
     2521 tttactcagc agaagaagca gccgtcttag tgaatgaagg cttgaaaatc attgattggg
     2581 cttcgacagc aaaagaggag gaacctgaat tggtcattgc tgctgcagga acggaatcta
     2641 acttagaagc attagcagct gtaactttgc tgctggaaga attcccaaaa ctaaaaattc
     2701 ggttcatcaa tgtcgtagat ttattgaaat tacgtcatcc aagtcaagat ccgcgtgggt
     2761 tgagcgatga agaatttgat caatatttta caaaagacaa accgatctta tttgctttcc
     2821 acggttatga aacattggtc cgcacgattt tctttgatcg tcataaccat catttaatga
     2881 ttcatggcta caaagaaaat ggagatatca cgacaccatt tgacatgcgt gtagtaaatg
     2941 aacttgatcg ttatcatttg gcaaaagacg cagctttaaa aatcaaagga agtcaagcag
     3001 aagattttgc gaaaaaaatg gatcagaaat tacaagaaca tcaaaactat attcgtgaaa
     3061 atggtattga tctgccagaa gtattggatt ggaaatggaa aaatcttgac caataaaatg
     3121 ataaaatcga tcccgcaaaa tagaattttt tacattgatt aagaaactga aaaaataaat
     3181 aaaaaaaacg gaaaaaagac tggaagaatg gccagtcttt tttttcgttt ttgggaagtg
     3241 aaaaccaaac tatttacctg taagccaccc ataaatccaa tcaaatggtg caaagaaaaa
     3301 atcttccatt ctattccctc ctttaaaaaa gcataacatg atttctattt acgtgagcat
     3361 gaattttgtt acgtttttat tgccgaaaaa taaaaaccgt tcattatgat gtcaaattcg
     3421 tcagtaattg atgcaatgtg ttataataat tcagttaaat caaaaatgaa atggagaaaa
     3481 gacatggacg ggttattacc tttatggaaa gaacgcggaa tgacaagtca tgattgcgta
     3541 ttcaaattaa gaaaaatctt acatacgaaa aaaatcggac atgggggtac gcttgaccca
     3601 gacgtagacg gtgtgttgcc catttgtatt ggaaaagcca caaaagttat cgaatatttg
     3661 acagattctg ggaaaatcta tgtaggcgag ataactctag gtttcagtac aacgacggaa
     3721 gatcgatccg gagaacgggt agaaacaaaa ccagtagata tgtctttatc tgaaaaaaaa
     3781 atagatgaag tgatggcttc atttattggt gagatcaccc agataccacc aatgtactca
     3841 gcggtaaaag tcaacggtaa gcggttatat gaatatgccc gcaataatga aacagtggag
     3901 cgtcctgtta gaaaggctca gatttaccgt tttatccgga caagtgaatt gacaagagac
     3961 gaagtgacag gaaccatttc ttggcgcttc gaagtagaat gcgggaaagg aacctatgtc
     4021 cgcacattag ctgtagatac aggcaagaaa cttggttacc ctgcgcacat gtctgatctg
     4081 acccgaacag caagtgccgg tatgtcccag aaggatgctc tgacattaga agaagtagct
     4141 caagctgtga aaaatgggac aatcgatgat tgtttgctgc caatagaaaa aggagtggaa
     4201 cggttcaaac gagtagatat tactgatgaa gtatggcaga aagtaaaaaa cggtatgaga
     4261 cttgattata ctgtatttgc gctcccagaa atgccgtcag aagaaattgc tttgttttat
     4321 aaaggaaaag ttgtcagtat ttatcagcca aacccgaaag aaaaaaacaa attaaaacct
     4381 agtaaagtat tgagaaatga ggaataacga atgaatatca tcaagatcag acatccttac
     4441 caatcagaac aaattccaga agacgatgtc gttttagtgc tgggattttt cgacggcgtg
     4501 catatcggac accagaaagt cataaagaca ggtatggaaa ttgcacaaaa agaaggattg
     4561 aaattagcat tgatgacttt caatcagcat ccatctattg tctttaaaaa gatcgatcct
     4621 agcagcgtga aatatttgac tagccttaag caaaaagaag aaaaaatggc cgctttgggt
     4681 atagattatt tatatgaagt tgattttact tcttcttttg ctcatttagc accgcaggaa
     4741 tttgttgatc aatacatcgt agggttacat gcaaaatatg ctgtttccgg ttttgattat
     4801 acgtatggac caaaagacat tgcagatgtc gctcattttc ctgaatatgc caaaggaaga
     4861 ttcaaaatcg tcacagtttc taaagaagaa gaacaaggtg aaaaaatcag ctctacccgt
     4921 attcgtggat tactagacag cggacaagta aaagaagcag caaaactatt aggttgcaca
     4981 tatgaggtag aaggggtagt tgtccatggc gatgcacgag gcagactact aggattccct
     5041 acagcaaatg tcaaagtaaa gagcacggtt catttgccta aagaaggtgt ttatgtgtcg
     5101 gaaataaaaa ttggggaaac atggtatcca gccatgggtt caattggaca taatgataca
     5161 ttcggtgaag gacgggagct gactgtagag ttgtatattt tggactttaa tcaagatatc
     5221 tatggtgaac atgtcgcggt acgctggaat caatttttaa gagatcaagt gaaattttct
     5281 agtgtagagg aattgattga acaactcaag gaggatgaac aagcaacagc tgaatatttt
     5341 tctcagcaat aaaacattat gcataaaatc tcttgtttat gtataactag caattacaat
     5401 aaaatgggtg ataaataagc ccaggaaagg ggctgtgaca aaagtcttgt cacagccttt
     5461 ttttccaaat aaatggtttt tcagaagtag cttcttcgga aataagccga aatttcttga
     5521 agctgaccac ttctgtcaca acctctttct ttatagaaat aaaaggacac tagcaattca
     5581 tgaaaacgat tgctagagcg tatcatttgc tttagactat atatcttggt gtacactcac
     5641 tttaaggcgg aaataaaagt tatccgtaat aacaggttta ggtatgaaaa aggagtgggt
     5701 actatgtaca aggaattaga aaacaaagtc gcagtagtaa ctggtggctc aaaggggatt
     5761 ggaacagcga ttgctcaacg attcgggaaa gaaaaaatga atgtagttgt caactataac
     5821 tcggataaag aaggagcaga aaaagcagtc aaagcaatcg aagaggcagg cggaaaagca
     5881 gtctctgtac aagcagatgt cagttctgaa gaaggaatac agcgtttact tgatacggct
     5941 ttagaaaatt ttgggacact ggacgtttgg gttaataatg ctgggatgga aaatcagcat
     6001 ccaacccatg aacttagcct tgaagattgg gaaagagtgt taaaagtcaa tttgactggc
     6061 gtttttatcg gaacgaaagc ggctttaaat tactttacag agaataataa aaaaggaaat
     6121 atcatcaata tgtcttctgt tcatgaacag atcccatggc caacgtttgc tcattacgct
     6181 gcttcaaaag gcggggtaaa attatttacc gaaacggtag caatggagta tgcaccgaag
     6241 ggaatcagaa tcaatagtat aggccctggt gctatccgta cacctattaa tgcggcaaaa
     6301 tttgatgatc ctgaacaaaa agaactcttg gaaagtatga tcccactagg acgcgtaggt
     6361 gaaccaaaag aaatagcggc gacagctgca tggttggctt cagacgaatc cagttatgtt
     6421 acaggtatta cactatttgc agatggtggg atgactttat atccttcttt ccaaggtgga
     6481 aaaggataag ggtgaataaa aatgggttta ttgattgcat tgatcccggc agttggctgg
     6541 gggatccagc cactgatttt gaaaaagatt ggtggcagac caacaaatga gatattagga
     6601 actggtattg gagcggtgct tgtcggctta ctcgttcaat tattcgcttc tccagctggt
     6661 atttcagtga ctacattttt gattagttta ctttctggtg cattttgggt tattggacaa
     6721 acaggacagt atacatcttt caacttgatt ggtgtttcta aaacgatgcc aatttcgact
     6781 gcattacagt tagtcggaac ctcgttgatt ggtgtcttcg cttttggaga atggtctgga
     6841 agtatgggga aaatcattgg agcagcagca atcattcttc ttgtatttgg ttctgcttta
     6901 acggcaatca gtgatgatcc tggaaaaaaa ggcggtatca caaaaggaat tagtctatta
     6961 gcatcaacaa gtattggtta ttgggtatac agtgcattgc ctaaactagt tgatgcaagc
     7021 ggactttcca ttttctttcc gcaaatgatc ggtgtctttt taggggcagt gatttatgtg
     7081 attttccgta aaccaaccgc attttctgaa gacaagagtt ggaaagcaac gatcgttgga
     7141 gccatcttta gtgtgtcagc attggcttat attttttcag caaatgaaaa tggggttgct
     7201 actgcatata tcattacaca gctaaacgta gttatctcta cattaggcgg tatgtacatc
     7261 ctgcatgaaa ataagacacc aaaagaaaaa aaattaacga ttatcggatt attgctgatc
     7321 gtagtaggaa gcatggtcac ggtctttatt tgaggataaa gatggtaaaa tttcatttat
     7381 taaaaaaata tttgtttgaa ccaaacagta agtacttata aaaaaatagc gctagaattt
     7441 ccaacatctc tggaatttct agcgcttttt aattgtttaa gatacaaggg aaatatctgt
     7501 ctggatcaat aatttttcat tgatccattg actaaagttt acgacataat tgaagttacc
     7561 accgattagt atctccgcat gattgtcttt ataaagatcg tattgtaaaa gacggtcttt
     7621 tttatttgcg taaacatcgt tatggtactg gactaattgt tctcggaatt gattgattgc
     7681 tgtaaaatca cgatattgaa ggttgaaacg catcgtgatt ggtgcattta gcatgaatcg
     7741 ctgcatttct tttgctgctt cctctgcttg atctccgtat aggaactcaa aaagattacg
     7801 ttcagaaaat ttccattgcc cgccaacctt tgttcctttt agttttcctt catgaagata
     7861 atttctgata gaacgtgtag taacacctaa ttgttcggct aattcattta ctgagtaaaa
     7921 atctttcaat gttcaccctc ctatgtgaat ggttctactg acttagttga tatttgctta
     7981 atcacgaaat gtagaaagaa cgattttaat taaggtcatt gtaaaaatca agtcagaaaa
     8041 ttctaacttt tatttctcta aagaaattcg ttctctccta aagtgatatt atatttaaat
     8101 atacctgaaa ataatgggca gtattatgaa agatcactga tattttctcg tattttttcc
     8161 ttattcaaaa gttttgcagg aaaattgctg aaaaaataat tttactaagt agaaaattca
     8221 aagccattca atcagtgatt tttttcagca caagaaagac tccttataaa aatagcagat
     8281 actttgtcaa ttaagtgttt aaccagggat gataaaaagg ataggattga acaaaacctg
     8341 tataaggtga tgaatagttt cctcgccagt aaaaggttta ttcgtataaa gctttatcgc
     8401 caaaatttat catgaccttt tttatcttca atattaaatg aaatcaattg ttcaatcaat
     8461 tcccagttga ttacactttt ccaaggaact ttgatgacgt tatccgtata tacgtagcct
     8521 gcttcttgga tatttttttc aagggcacga atcgctgctt tttccggtgc gatagaaaaa
     8581 tgatttttag caaaactaaa tgcaataata aaggtaccat ggtcagtaaa cataggttgg
     8641 ttccatttta cagttgtgtc tagctgggga tacgtttctg ttatcttagc aaaaaggtct
     8701 ttgatctttt gttgatgttc tttttctttg atttgattga tgatcggctg aaatttttcc
     8761 attctaaaac gcctccatta agtggtttga tttattttac cagaaaaaca atagttatgt
     8821 ataaaaaacg aacaaaacac aagtaatgtt gtaaccgcta tatttatatg ataagatgtc
     8881 tcaaataata aaatagaaaa gagacataaa aatgattgac ttggcaaaga aattcttaca
     8941 cgaaaatata tattttgagt tgtatcatca tcgagccatt tatacaaatg aagatgcttt
     9001 ggtaataaag aaagaacaag gatttacagg tacagagacc aaaagcttat tcttaaaaga
     9061 taaaaaagat aataactacg tatatctgac ttttactacg aaacaaacgg atttcaaagc
     9121 attagggaag atcgtcggta aaaggctttc tattgtttca tcagaacgca tggaagaaca
     9181 aacgggacaa aagcagggcg ctgtttctcc gtttggttat gaaaaacaga ttccgattat
     9241 tattgatgaa gagctcttat caaatgaaaa acttgttttt gcaccaggta gaccagatca
     9301 aacgatggtc atccaaacgg ttgacttaaa caaaatcatc cagctacttg agatgccgat
     9361 atttttgatg ccggcaaacg aaaaaaacaa ttaaccaagt aaaatagtgc atacttggag
     9421 gtgaagcaac atgataagtt atccattatt agaaagaaat gcaacgattg gggttactgc
     9481 accatcctca ggcgtatcag aggaacacca ttcgttactc gaatcagctt taaagagaat
     9541 ggaagaaaaa tctttccaag tagttactgg aaagacgctt tggacgcaag ataaggaaaa
     9601 atcaggtcca gcaagaaaac gagcagatga attcaatcaa atgatgcaag atgaaaatat
     9661 ccaaatgatc tttccgactt ggggaggaga attattgatt gagattctcg attttgtcga
     9721 ttttgatgct ctacaaccaa aatggatagt aggttattca gatattagta cgttgctact
     9781 tgctgtcaca ttaaaaacag ggatagccac tgcacatgga actaacctta ttgatttaag
     9841 aggagagtac ttggatgaaa cgacagcaat gtgggaaagt gtactgaaaa caagagaagg
     9901 agaatcgatt ctacagcaat cttctgaaaa gtatcaaaaa gtgtggcccc atgagcattc
     9961 atcatcttct gttttccatc tcactgaacc aacaaattgg caatcagtca gcggagatgc
    10021 agtaaggatg aagggacgat tattaggtgg ttgtattgat acgatcaggc atttaatcgg
    10081 tactccttat ggagatgtcc aatcttttaa aagaaagtat aatgatggaa agccgatctt
    10141 gtggtttcta gaaaactgtg agctatcgtc agttgattta agaagatcac ttgttcagat
    10201 gaaactggca ggctggtttg atggcagctc ggggatcatg ttcggtagaa gtgcggcaga
    10261 ggatttgtta gattataaaa tgaaggatgt atacgaagat ctgtcaaagg aattaaaact
    10321 accgatcttg tatgatattg attgtggtca tgtaccgcca caactgacat tgattaatgg
    10381 tgcctatgca gaagtagcgg tagaagatag aaaagcgact gttttgcaaa cgtttattta
    10441 aaaaattttt tcctgccttg gagtctatca aagaccaata aatctaaata gaaaagaaag
    10501 tgaaagaagc tgacaaaatg ctgtcagctt ctttttgtat aacatattag aaagtctaat
    10561 tatctataac tgtcacatcg attaactgtt tcacgtcatt gggatttcct gtaggaatag
    10621 ctactacaga tgcattatca atgatttctt gagttgtttc tctaatgaac gctggataag
    10681 atgtttgatc tgcaggcatt tgccaatgtg aaggaactgg ataactagtg attgtcccgt
    10741 catggttact tgaatacact aaaactccct ggtaactgta tttcccagtg agcataacca
    10801 catctttcgg atagactgca ctccctgcat cataaggggc gataggtgtt cctgcaggat
    10861 aatgaataac atgtaattcg aaatcacccg atgtatctct aaaagtatta cctctaatag
    10921 ctagccaaac acgtgcgtac tcaatttgta gatcagaata tcctgctaac ggatctattg
    10981 actgagaaga ctgtgaggag gttgtgtcta ttgttgaaga agaaatattt gtctcaactg
    11041 tactactaga tgtagaagaa gtattgggct ctgagacttt actgcttgtt gaagatgtat
    11101 tcgtttcagt agaagctgat ttctgagtac ttgatttttc agctgaactg gtttgtctga
    11161 ttgaactttt gtctgtggtc gcagatggat cactattttc tttactagga gacgtacatc
    11221 ctacaaggaa taaagagacc aacaataaaa taaaacctaa ctttttcata taaaatacct
    11281 cattattttt ttaataccag tatagcataa tcctgaattt ttgaatccgt aaaaccttgt
    11341 ctatgaatat aaatagagtg tatcttcttt gataaatgtc agaaaaagtg tgacaaataa
    11401 tcatcagtaa aattacttgt cacactattg ataaggagta tttaattgaa gagaatgatt
    11461 aggagaaagg atctccgtac tttttatagt aatcatagaa tccaagtttg tatagacgaa
    11521 tcgttttttc tcttatttct tctgtttcaa aatggactgc ttgaagaatc aagtctgtga
    11581 attctatagg agctgttcca ttcgcagtaa tcaaattacg atctttcaca gcttgttgtt
    11641 ctataaaatc ttctttattc tgataatttt ccgattctaa ccaaggaaat tgcgcatttc
    11701 cggtgtgttt gtaaccttgc aataatccgc tctgagctaa ataatcaact gccccacaaa
    11761 tagcagctac tggtacgtct gtttttaaca atttatcgat tatttgatat aaatgatgat
    11821 tttttatgtc ccatgaattg ccaccgatca taataaaaag gtcaactttt tcaggtattt
    11881 gttcgattaa gtaatcgatt tttgttttta atcctccaat ggaagtgacc tctgattgga
    11941 tagaagcagt tttgttttgc catttctcat tttggtttag tgtgctagta atataagcac
    12001 cttcccaatc ggcatattcc tctaatagaa acgtaatcgc agttttcatt ttcaagctct
    12061 cctttactat ctataacaag gacaacagtt ttaacctaca gacattcatt aaaattgggt
    12121 agcgacagcg aaaacaacaa ttcttaagtt ttagacagag tatacagata gtcaacttaa
    12181 ttaaatacga actaaataaa aatgacaggt aatcattttt gtttaccagc attataacat
    12241 tttgcataca tggatgacaa aagaaccaat tcccacttgc ttgagtacaa tattaaaaga
    12301 aactggaagg caaaaagtaa ttatagaaac gaaaaataaa tcatatcggg cactcagaca
    12361 tgaaaacaac cctagagata tataactagg taaccagttt aatgaaagaa aaaatcatcc
    12421 aagaagtcga ttcttggatt ttttagtgga tttgttcgcc aaatacgttt agtatgcgta
    12481 tatgagaggt tgtaagcaaa gcgttgtggt ctgagcactt aaggaggaat ctgtgaaaat
    12541 agcttttcat atttttgcag attttgactt aatgccgaag gtcagctttg cgattaccgt
    12601 ttatcgagag gctgtaaaag caccgtgtag ctccgatgac aataagcaag catttttaga
    12661 gctaggtttc cttgattcta aatatgcggc ttatttcaat gagttggtgc ttgaacgcga
    12721 ttttaagaag gtcgaaaaca ggcacgactt ttcgacgtaa ggagaaagaa tttcaatgat
    12781 agaaacaata aatcccgcag aaaacaaggt ttctgcgtac attcatatcc cattttgcga
    12841 gcatatctgc tattactgtg attttaataa agttttttta gaagggcagc cagtagatga
    12901 gtatgtggaa atgctgctga atgaaatgaa aataatgcta gaaagtcatc cgacagcgaa
    12961 tttagaaaca ctttacgtag ggggcgggac accaacttct ttatctgcta aacaacttga
    13021 tcgactgtta tcaggtgcta gagagatcct gccttttcaa aatggtaatg agtttactgt
    13081 agaagcgaat ccaggtgatt tgacccgtga aaaacttcaa gtaatgaaaa actatggcgt
    13141 caatcgttta tccatgggag tgcagacatt tgataatcgc ttattgaaaa aaattggacg
    13201 taaacacacc gcagaagatg tgtatcaaac tatgcaattt ttagaagcag aaaattttac
    13261 caatgtaagc atcgatttga tttatgcatt accgggacaa acactagaag gatatctgga
    13321 tactttggaa aaagctttgg ctttggatct gcctcactat tctttgtact cattgatcct
    13381 cgaaaacaaa acaatgttca tgaactgggt acgacaagga agactcgaac tgcctgatca
    13441 ggaaacggaa accagaatgt ttgaagagac gattgaagca atggaaaagc atggacgtca
    13501 ccaatatgaa ataagtaact ttgggctctc cggacatgaa tctcaacata acctcatgta
    13561 ctggaacaat gaccactatt ttgggtttgg agctggtgct agcggttatc ttggagatat
    13621 tcgttaccgc aacaaaggac caatccaaca ctatttacgc ccattacgag caaatgaacg
    13681 cccggtattg gaagaagaaa aattgacacg aaaaaatcaa atagaagaag aaatgttctt
    13741 aggactaaga aaaaaacagg gattactaaa aaacatttct atgatcgcta tcaaaaaaca
    13801 attgaatcgg tgtacggtga tgtgctaagg gaattagagc aagaagggtt acttgttaat
    13861 gaagaagacc gtgtttattt gacaccaaga gggacctttt tggggaacaa tgtgtttgag
    13921 cgctttttgt ttgaaaaata gtttaaagaa tatttgtttt ttatctgaat ttaaataaaa
    13981 aaagttcaaa aatacaataa aggactattg aaacgttgat ataactggat ttacatcaat
    14041 tatttagaat tagcactctt gtgtttagag tgctaaaaaa tggagtcttt ctcttgacag
    14101 gagaagggct tcttgctata tttataagtg gattagcact tagaatatat gagtgctaat
    14161 gagaggtgag gaagatgtta acaaagcgac aaaacgacat tttacgtctg atcatccaac
    14221 actatacgag tagtggcgtg cccgttggtt ccaaaacatt gatgtctgag ggagtcaagg
    14281 ccagctcagc aacgattcgc aatgatatga aagcattaga agatgaagga ttgctgttga
    14341 agactcactc ttcttctggg cggattccat ctgctttagg ctatcgttat tacgtggatc
    14401 atttgttaaa acctgctcgc gtagcagaag atgatttgct gctgattcgt cagtctctag
    14461 gcagagaatt tcatgaaatc aatgagatta ttaagcaatc tgctgagata ttatctgagc
    14521 tgacaagcta tacgactttt tcattgggac ctgaaataaa agaccgccga ctgactggct
    14581 ttcgtatcgt acccttgaat aatcgacaga ttattgctat cgtcgtaaca gatatgggga
    14641 atgtagaaag ccaagtgttc actcttcccg aatatatggg aagtcaggaa ctagaaaaaa
    14701 tggtacagat tgtaaacgac cgtctagtcg gagatcctct gatgacggtg taccataaac
    14761 ttcgtacgga gattccgatg attcttcata aatatttcca aacgacagaa gggatgtctc
    14821 agttatttga caccgttctt ggtcatgttt ttgaagataa ggtttatgtc agtggacaaa
    14881 tgaatctctt ggattatgag ccccgtcaag atcttgatca gttcaaatcg atgttttctt
    14941 ttatgaaaga ctcagacgga cttacacaaa tgatcactcc gatggatagc aatattcata
    15001 tcaagattgg tgctgaatta ggcaatgatt tattgcagaa tatgagtatg attcaagcaa
    15061 gttacgagat agatggtcat ggaagaggta caatagcctt gttagggcct actagtatgc
    15121 cttattctcg gatgttcggt ctagtcgatg tttatcgaag agaactagca gctaaacttg
    15181 ctgattacta ccgttcgctt gacttgtcaa actcgtaatg tgaataacga agctatttgc
    15241 agctgatcgt tctctctttc ttagtaagag caatcaaaca gctgactgaa taatgaaagg
    15301 aagactgtat cgtgaaagaa aatcaagaag aactagataa agaaatgaca gatgctcagc
    15361 cagaaccgga aatcgatgtc gaagctgcag aagattcggg tatttcagaa gctgaagcgg
    15421 aagaattcga aacagcgaaa ttaaaagctg agttagaaga aatggaagat aaatacttgc
    15481 gggctcgtgc tgaaatcgca aatatggcaa atcgaggaaa aaatgagcgt gagcaattac
    15541 aaaaataccg ttcacaagat ttagccaaaa aattacttcc atcaattgac aacctggaac
    15601 gtgcattagc cacagaagtg tcagatgatc aaggggcagg tttgaaaaaa ggcgtggaaa
    15661 tggtcttgga aagtttgcgt aacgcactgg aagaagaagg aattgaaaaa atccctgcta
    15721 aaggagaagc ctttgatcct aatcttcatc aagcagtaca aactgttcca gcgactgaag
    15781 atacaccagc cgatacgatt gtagaagtac tacaagaagg ctacaaatta catgatcgcg
    15841 tgttaagacc aaccatggtc attgttgcac aataattgtg cggatataaa acttacactt
    15901 tcaattaaag aaggagacgt taattatgag taaaattatc ggtattgact taggtacgac
    15961 taactctgca gtagcagtat tggaaggaaa cgaagcaaaa atcatcgcta acccagaagg
    16021 aaaccgtaca acaccttctg ttgtatcatt caaaaatgga gaaatccaag taggggaagt
    16081 tgcaaaacgt caagctgtga caaacccaaa tacgatttca tcaatcaaac gccatatcgg
    16141 tgaagcaggt tacaaagtag atgtagaagg taaatcatat acaccacaag aaatctcagc
    16201 aatgatcctt caatatatca aaggattcgc agaagactat ttaggtgaaa aagtcgaaaa
    16261 agcagttatc actgtgccag cttactttaa tgatgcacaa cgtcaagcaa caaaagatgc
    16321 tggtaagatc gctggtctag aagtagaacg tatcgtcaat gaaccaactg cagctgctct
    16381 tgcctatggt ttagataaaa cagatcgcga cgaaaaaatc ttagtattcg accttggtgg
    16441 cggtactttt gacgtatcta tccttgaact aggagacggt gtctttgatg tattgtcaac
    16501 agctggcgac aaccatctag gtggggacga ctttgataac aaaatcatcg actacatggt
    16561 agcagaattc aaaaaagaaa acagcattga cttgtctcaa gacaaaatgg ctttacaacg
    16621 cttgaaagac gctgctgaaa aagcgaaaaa agatttatct ggcgtatcaa gcacacaaat
    16681 cagcttgcca tttatcacag caggagaatc tggaccattg catttggaaa tgacattgac
    16741 acgtgcaaaa tttgatgaat taacagctga cttagtagaa cgtacaaaag taccagtacg
    16801 tcaagcgcta aaagatgcag gtttatcaca atcagaaatc gacgaagtta ttttagtcgg
    16861 tggatctact cgtatccctg cagttgtaga agcagtacgt aaagaaacag gaaaagaacc
    16921 aaacaaatca gttaaccctg atgaagtagt tgctatgggt gctgctatcc aaggtggcgt
    16981 gatcactggt gatgtgaaag atgttgtttt acttgacgtt acaccattgt cattaggtat
    17041 cgaaacaatg ggtggagtgt tcactaaatt gattgaccgc aatacaacga ttccaacaag
    17101 taaatcacaa gtattctcaa ctgcggcaga taatcaacca gcagtagaca tccatgtatt
    17161 acaaggtgaa cgcccaatgg ctgctgacaa caaaactcta ggaagattcc aattgacaga
    17221 tattccagca gctcctcgtg gtattccaca aatcgaagta acattcgata ttgataaaaa
    17281 cgggattgta aatgtatctg cgaaagatct aggtacacaa aaagaacaaa aaatcacgat
    17341 caaatcttct tcaggtctaa cagacgaaga aatcgaacgt atggtaaaag atgcagaagc
    17401 aaatgcagaa gcagataaag ctcgtaaaga ggaagttgac ctacgtaatg atgtagatgc
    17461 attgctattc tctgtggaca aaacattgaa agaattagaa ggcaaagtgg acgaagaaga
    17521 agtgaaaaaa gcagaaacag ctcgcgatga attgaaagcc gctgttgaag caaacaacat
    17581 cgaagaaatg aaaactaaac gcgatgcatt gaacgaaatc gttcaaaact tgactgttaa
    17641 actatacgaa caagcggcac aacaacaagc tcaagaaaac ccagaagcag ctcaaggcgg
    17701 agcagatgat gtcgttgatg ctgattttga agaagtcgat ggcgacgata aataatcagt
    17761 tcactgaatt tcgagagaag gccaaagttg ctactttggc tttttctttt gaaaaatagt
    17821 ttgaagtatc ggtttttgtt tcaaacaaaa tatgatatga taacaagcga cgtgaaaatg
    17881 atgagaacca ataggaggaa agcctatggc aacaaaacgt gattattatg aagtcttagg
    17941 gctctcaaaa ggagcatcag aagatgaaat aaagaaagct tatcgtaagc tttcgaaaaa
    18001 ataccatcct gacatcaata aagaacctga tgcggaagaa aaattcaaag aagtatcaga
    18061 agcatatgag attttaagtg acccgcaaaa acgcgctgca tatgaccaat acgggcatgc
    18121 aggcacagat ccaaattacg gtgctggtgg agctggtggc ggatttggtg gattcggcgg
    18181 cttctctggt ggcggcttcg gtggttttga agatatcttc gactctttct ttggaggagg
    18241 cggtcggtca gtcgatccaa atgcgcctcg tcaaggtgct gatttgcaat atacggtcga
    18301 cttgtctttt gaagaagcga tttttggtgt agaaaaagaa atcaagtata atcgggaaga
    18361 aatctgtcat acttgtggtg ggaacggtgc aaaaccaggc acacaaccaa ctacttgtca
    18421 taaatgtcat ggtgcaggta cgattaatgt agaacgccaa acaccacttg gacgagtgat
    18481 gagccgtcaa acttgtgatg tttgtcatgg gacagggaaa gaaatcaaag aaccttgtcc
    18541 aacctgtcat ggctcaggac atgagaagaa agcacattca gttaaagtga atgtaccagc
    18601 tggtgtagaa gaaggacaac aaatgcgttt agctggtcaa ggagaagctg gagaaaacgg
    18661 cggaccattt ggtgatttgt atgtggtctt ccgtgtagaa gaaagtgata tctttgatcg
    18721 tgaaggttct gaaatttact atgaattgcc tttaagtttt gtacaagcag ctttggggga
    18781 tgaagtccaa gtaccaactg tccatggaga tgtgaaattg aagatccctg ctggaacaca
    18841 gacaggtacg aacttccgtt tacgtggaaa aggcgctccg aagttacgtg gtggtgcaac
    18901 aggcgaccaa catgtcaaag taaaactgat cacaccgaaa aatctaaatg aacaacaaag
    18961 agaagcatta cgtgcattcg ctgaagctgg cggcatcaaa gttgaagaac agcaagaaga
    19021 cggtttcttc gataagttta aagatgcttt tggcgggaaa aagcggaagt agtttttcta
    19081 gtaaaaacgc taagtcatta ataattaaaa accagacgaa caatcatatg ttcgcctggt
    19141 ttttttgtag ttgtcatgtt tgtaccaaca aaaaagccag ctttagaata tgataatcgt
    19201 catagtttct aggggtataa ccagtgagag aatggaactt gttcaatcga tattgcaagg
    19261 tgtttttatg aataaataat tcttctgagc aatttttgat gcttccgtta tttttactga
    19321 agcatgccaa agtcttcttg aacaaatgta cttcttcttc tgtcaggctt ttcaaaatac
    19381 gttttacata taatgttcgt tgatctgacg ggattgctgg taaaacgatc ccgaggtcta
    19441 aatcttcaaa aaagcggatc tcgttcacag attgatggaa agctatccat tcgcaaactt
    19501 gtttggcatg aaggaaagat tgcggtgtct cttgctctgt ataacaaagc gacccaattc
    19561 caaagtttag ctgtaactga tacattttat taaactttgt ctggatttta tcaagcaatg
    19621 atagcaatga ggctctggaa atccgattga ctaggataat gatttgttgt ctatgtacag
    19681 tgagcaaagc ctgtccgtaa taagagaaga ccctttcgag caactccaat aaaggattga
    19741 tccgttcttg acacaattgc tgattgtcag aaagttgtcc cacaactaca taatatggag
    19801 aagaaaaatc aagctcaatt aagtgagggt ggtatcgact atgtacttga tatcatcaat
    19861 gaaccgatgg tactttctta tgcgatggaa caggtagagc gattgcttgt ttgtgcagga
    19921 aaacaagcga tgcggctgat acgattaggt gagaaaataa gaagataaaa atacacggtc
    19981 ccttcatggc gaccgtgcat ttttggtttt tattaaattt tatatctaat tttcaattat
    20041 ccgcataaac actatacatt caagcatttt gaagtataga aaaacactca tcttaccacg
    20101 aatttaccac gattgaatga gccttgatat gaccgtaaaa ctactaaggg agataacacg
    20161 aaactgtgta tctcccgatt tttttataca gttgattact tcactccgat ttcaaatttc
    20221 aatattgctt tcatcatgtc tgtatgaatt tctcctttta gttcttcatc aacctgcata
    20281 atgattttac cactttcaga gtggtaaaaa ggacgcaagc ataatttaga aatataaccg
    20341 tcataaaact tcaaaatctc tttaactgcc atttcatctc cgcttgacgc tttgcaaatc
    20401 aattcaaaag agggatagcc ataatcttta cttcctttcg ctcaaaagca tttttaactt
    20461 ccttagtcct ctagttcttc tactgcaaat agcagaacgt gatacatggt acagttctga
    20521 aatttctctg tcgttcattc cttgaaaata acgtaataaa atcgcactac gctgtttttc
    20581 tgatagtcta tgtaaaactg taccaagtgt ttcatcagat acataaattg taaagtgcaa
    20641 gactttaaat gatacacaat cataaaaaca ggtatcaatc gttccacgtt caacttgttt
    20701 cgtttcggct atttcacaaa acaatacttc acgtttagaa tgtcttgcaa gctgtctgtt
    20761 tcgacttttc actttgttct taatgacaat cagcattaaa gaattgaact gtaatctgac
    20821 gatatgctcg aaagaagatg tcctcataat ctcaccccct ttctgtctag gaaaggaagt
    20881 gagccttgct cgtttatctc ctttcactct tagtcccaat gtgaaagggg gatttgttgc
    20941 attactgata aataaacttt gtaaaaaagt tctgaatagc caaaaaagca tataaacaga
    21001 tttatttctc tgtttacatg cttctgttat tctatctata tgatttataa aaccacattg
    21061 gtggacgtac ttatctattg cagatagacg actttttttg acaagaaccc aatgtaagga
    21121 aatttattgt atatgatgta cttcatggcg acgttgacct ccaacaaacc gccatttgga
    21181 agtaatatac aatattttaa cagcgtaaat agcactacca tataacggtt ttttttattg
    21241 gcgtttagta gtgcttttta ttaaatataa acctataaac catataacac gtttttctat
    21301 acctgttttt aattcagtag gaacaataaa atgtatagag gtggtctact atgcgtaaaa
    21361 aagaagataa atatgatttt agagcctttg gtttagccat taaagaagct cgattgaaac
    21421 gaggtttaac tcgtgaacaa gtgggagcat tgattgaaat tgacccacgg tacttaacta
    21481 atattgaaaa taaagggcaa caccccagca tacaagttct ttatgacctt gtatcgttac
    21541 ttcatgtttc cgttgatgaa tttttcttac ctgctaataa cttggtaaaa agcacccgac
    21601 gattacagat agagaaatac atggatagct ttacagacaa agaactatcc ttaatggaat
    21661 ctttagccag cggtatcaac gaagcaagaa acatcgaaga ctaattaaaa gaatccatac
    21721 ataacggaaa gagccgataa aatgagattg tattaatctc attttatcgg ctctgcgtct
    21781 ttgcgtctgg ctctgtaatc acagttactt tgaactgctt tatttcaatt aaattttctt
    21841 gtctgcattt cggacaatag agggggaatt tttttaattc agtatcttcc cttatcttta
    21901 atcgtgtttt atttccacat acaggacaca atatccactt gtagtttata ataactat
//
LOCUS       DAPBAF010000048        21924 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.048, whole genome shotgun sequence.
ACCESSION   DAPBAF010000048 DAPBAF010000000
VERSION     DAPBAF010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 21924)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21924)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21924
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.048"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            283..522
                     /locus_tag="RD451_002198"
     CDS             283..522
                     /locus_tag="RD451_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567429.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
     gene            complement(884..1144)
                     /locus_tag="RD451_002199"
     CDS             complement(884..1144)
                     /locus_tag="RD451_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567430.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVVGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(1329..1826)
                     /locus_tag="RD451_002200"
     CDS             complement(1329..1826)
                     /locus_tag="RD451_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HDT7567431.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANFNINAF
                     SFINN"
     gene            complement(1956..2666)
                     /gene="budA"
                     /locus_tag="RD451_002201"
     CDS             complement(1956..2666)
                     /gene="budA"
                     /locus_tag="RD451_002201"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HDT7567432.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            complement(2679..4343)
                     /gene="alsS"
                     /locus_tag="RD451_002202"
     CDS             complement(2679..4343)
                     /gene="alsS"
                     /locus_tag="RD451_002202"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HDT7567433.1"
                     /translation="MDEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVGKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAELTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            complement(4548..5210)
                     /locus_tag="RD451_002203"
     CDS             complement(4548..5210)
                     /locus_tag="RD451_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HDT7567434.1"
                     /translation="MKEQRFDKNVYMEFFYWLYQSLASSLCFWCVNILYIAAAFLLSI
                     DGRNVFSFIFSLLFIGPGCIVMIGMTEELAKEKSFSPVRLFIKTFRQFWLKGFFYWLF
                     AWIVSVIMIFDCFFFIRFSYGKWLIPLFVLLACLSVSFSINYWYFQVRNPASKPNQVL
                     RIAFYYTLKKWYVSLLDFLLLTSLFLFFFVKPQWCILLGPSIVFGLIYFNNRKLMRTM
                     DL"
     gene            complement(5220..6035)
                     /locus_tag="RD451_002204"
     CDS             complement(5220..6035)
                     /locus_tag="RD451_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDT7567435.1"
                     /translation="MPFIQWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQW
                     IPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDI
                     LFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWSLVLLQAFNAFGVFLLKQYYSSIP
                     DSLCESARIDGLSEWGIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENK
                     TIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMKE"
     gene            complement(6297..6740)
                     /locus_tag="RD451_002205"
     CDS             complement(6297..6740)
                     /locus_tag="RD451_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HDT7567436.1"
                     /translation="MLDPVDTEKYETILLPRKEKWGLLILENSVLAKKDVITKEDFAN
                     VPLLISKRPEIQRMFADWLGIKKEQLLITGTYNLIFNVFALIENQVGAALVIEGAVSH
                     LSKRVTFVPLDPMIETNCMLVWKKNRILSPVVNELIHRFKEAFEQ"
     gene            complement(6874..7212)
                     /locus_tag="RD451_002206"
     CDS             complement(6874..7212)
                     /locus_tag="RD451_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDT7567437.1"
                     /translation="MYQVKKSRSIAMELRLLKYFWTIAEEGTISQAAEVLHLTQPTLS
                     RQLKELEEELGTELFVRENRKMILTEAGYFLKKPSRRNFRFNESNHSRIREQKKTIIQ
                     RPIYDRLCGS"
     gene            complement(7200..7577)
                     /locus_tag="RD451_002207"
     CDS             complement(7200..7577)
                     /locus_tag="RD451_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDT7567438.1"
                     /translation="MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDL
                     KWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKEIAEMQECL
                     ERLQGKIKKYDRVLSRNKMECIK"
     gene            7801..8994
                     /locus_tag="RD451_002208"
     CDS             7801..8994
                     /locus_tag="RD451_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDT7567439.1"
                     /translation="MTTYQRKVLLSTSAGIALENMDIMFLAFSLSSMITSFHISGTQA
                     GFISTITNLGMLIGGIFFGIIADKYGRVKVFSQTVLLFSIASLLMYFASNIYLVYLFR
                     FIAGVGAGGEYGACMSLISESFSKKQIGRASSVAGIGAQVGAALAAILAAVIIPTFGW
                     KMLYVVGVLPVLMVLFIRRGLTEPKEFKSVQSAEKKTKLSRLFESKHLAWQTCGLSIM
                     VTVQIAGYFGLMNWLPSIMQNRLGLSVSGSSLWMVSTILGMSLGMMTFGIIMDKLGPK
                     LAFSLFLICSSLSVYLLVLAHSQWSLVAAAVIVGYFINGMYGGYGAVISSLYPTEIRA
                     TANNFIMNLGRAVGGFSSIVIGFLMDHYSLTAVILFLSGIYLVSLLVLTTLTGVTALR
                     ESLQH"
     gene            complement(9160..9582)
                     /locus_tag="RD451_002209"
     CDS             complement(9160..9582)
                     /locus_tag="RD451_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7567440.1"
                     /translation="MQTFLTKVSQKKIKMIHLLLETERWCSIEELQNELKVSSKSILN
                     YLTDLEELFQKYPDKVILKNENNRRFSMEKQENFPIYIIYLHFYRKSYNYHLIEFMYQ
                     HPEKNLEDYADAQYTSVSTVFRYAKLLVKYFEMTDVKE"
     gene            9977..10171
                     /locus_tag="RD451_002210"
     CDS             9977..10171
                     /locus_tag="RD451_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567441.1"
                     /translation="MVAGSLLSGCGATTSTTQSTSSDQASSSSTTISESTADSSKEQE
                     QIEKKKEEKQKAEKAALEKK"
     gene            10168..10662
                     /locus_tag="RD451_002211"
     CDS             10168..10662
                     /locus_tag="RD451_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567442.1"
                     /translation="MTEAESALSQAEANPTKENYATASAAIQALPENKQELTSRLAAI
                     DSTIKAKEAEEERKKQEEIARQQAEQAQQEAIAQQQAEQARQEAIAQQQAEQARQQSA
                     AEQASQQAQAAAPEQNNEQTVYVTPTGSKYHTHKCGNGTYTPATLSEAQARGLTPCSK
                     CYGN"
     gene            complement(10824..11996)
                     /locus_tag="RD451_002212"
     CDS             complement(10824..11996)
                     /locus_tag="RD451_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HDT7567443.1"
                     /translation="MNKSRIRILDIFMAIILVVGIGIFSYPFVEDSLNDFLAQQMIIH
                     YQKQASNKNSEEIKKQQEKMTKKNQQLAEQNVSPGIGSFNQAVDAKALKDLPSNAFFM
                     EHMLGVIEIPKINVSLPIFDQTTEIFLQKGTSLLEESSYPTGGKNTHAVLSGHRGLPE
                     AKLFTDLPKLKKGDQFFIQINGKTLAYQVEKIQVVLPDEVDSLGIQKGRDLVTLLTCT
                     PYMVNTHRLLVTGHRIPYQAKEAKKAIQGIDQWKKWKFFIWFIGILLGSIGLVWLLIA
                     YLDSLAIAKRNYPLSFYVKNTNGRPIEGMVFSVKTLNGKHYITREKVPFVKASDEYGL
                     VRFSDLKGRNYRLQHEELLLKIHVKHKHSKQFSMKLKKGRYKLRKEKEVYYLIEKE"
     gene            complement(12202..13017)
                     /locus_tag="RD451_002213"
     CDS             complement(12202..13017)
                     /locus_tag="RD451_002213"
                     /inference="COORDINATES: protein motif:HMM:NF033902.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HDT7567444.1"
                     /translation="MTGFDENTGVALYDPAESALTFTTDTEGSISVNGLIDGNYTLVE
                     TKAPDGYQLTNPQKETTFIVKNGKLQQTTGIIHGADEANLGNPNGVVNRENTTTDNTI
                     TVENVQNYGDFHFIKQDVNTQEKLADAEFSILRAKDPTVKLMKKIANLASGEYPYAWS
                     DEVTGSDWEEVKLISDSEGKFSIEGLKQGAYCLQETKAPEGYALPKNEAAYTEFTVDD
                     DPTTSDETTIDNQPKGILPSTGGMGIIVFILVGTALVGGAVIYFKKRHQETEA"
     gene            complement(13167..13613)
                     /locus_tag="RD451_002214"
     CDS             complement(13167..13613)
                     /locus_tag="RD451_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HDT7567445.1"
                     /translation="MKNIKTKIWTFLGTAIMLLPFVLGLGTAEVSAAVSPTPENVTVN
                     LHKLKFTSAPENQINNGTELTFPNSEPLNGVEFNVYDITATYYPSKDTAVPADATPFA
                     SVTTSGEGLANLTLPGKSDGKDAVYVFVETPKPGVETSPNIVLSLP"
     gene            complement(13610..14614)
                     /locus_tag="RD451_002215"
     CDS             complement(13610..14614)
                     /locus_tag="RD451_002215"
                     /inference="COORDINATES: protein
                     motif:HMM:NF037639.1,HMM:TIGR04226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HDT7567446.1"
                     /translation="MTDSSNHKLTTIHLYPKSEQKIPAALTLTKTVENKQTDFADGDK
                     VPYLITVTIPENINEIGTYTIKDTADPQLWLEPETIDFLIGGDKIHTFHTQKIKHGFV
                     LSDSGKDLSSFAGKKLTIRYQMTLKENSEKTTFDNDVRLTTDNQTVETHLAIQTGGKQ
                     FVKVDRQTKQKLADAQFLVKKNDQYLAQENGINHWVAKDDSRATIFTSSKDGTFSVHG
                     LSFGSYELVEIKPPKGYILSQSTILFEVEKGSYDPLHPIPLEIINEPKANPTNNGKTP
                     VQMQTNGPSNEKNGGSFPKTSEEMLGGFSILGLLLVLSTGTAWFYKKQQKGNNRREIK
                     "
     gene            complement(14654..14983)
                     /locus_tag="RD451_002216"
     CDS             complement(14654..14983)
                     /locus_tag="RD451_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HDT7567447.1"
                     /translation="MFESDKMPSISQNDGINIPDNFQGVKGLNGVTFAIYDVSDEFYK
                     LRSEGSSVEDAQRKLAQKSDSEKILAENVTKTVDEEEGIASFSASDKDEQGRDAVYRF
                     TEIKTSD"
     gene            complement(15109..17436)
                     /locus_tag="RD451_002217"
     CDS             complement(15109..17436)
                     /locus_tag="RD451_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HDT7567448.1"
                     /translation="MKMIKKTQNKIQRICQKHFVSRLKAVSKRKYLHPIMISIILIFT
                     FLGSLSSIYVNVYTETSNFANQTTEETNSPPYSEIQSIESTNQSSNNETTSTTSSTQL
                     IDPTEKEITAAKAAGEKAYSETGRSQTFSTVAATANFNGHTIPDGYTVIYAKDGVIVA
                     VNGSMSADKTALQGVTKAIAFIDNRPDIHNLFIGSTVNGTTITFPKSIYMGVATAGNT
                     IDSVTPNADKSYSFTPSTWGGLPAGGGMSTFSIGIQLANDIPFTGYSIKNGQIVDGKG
                     NVSNFPTYQAATVQVNANRTGTFSYTVNGGAAKIGTYGTTLSGIHVGDKVVITPTAVT
                     GYSFAQTNGSFTALESNVDTVTYTGKQTPITIKYQDYFGQMIAPSKIMNLTYGSAAQD
                     LTTNTPTINGYTFTAVSAIETKNQSAMSVLASLDTNGNVIVKDANGKQISEVILYYKT
                     NATVSINANGSKYYDGLSVVPIVKYAFNDKTESTSLLNNDLSIDQITWNPTDFKAMNE
                     KGVEVTAPTEIGTYTSWQLTKSGLAKLAARTNYLFTIVQTSDVYTIKQISGAVELSGS
                     KTYDGKAGVPSIHVKLAEGVTSSLTPVQVALSSMDYTADAQSAKNMVNAGSYTIKLTN
                     SGIDKVKAANPKLSFTDIANTSGTYTIYKANAVITVDDAAFNYDAQSHSISVGNLHVT
                     GVVLGESLDYTLTVNSRTDIGSQIVTISLGEGSVNNNYTIIATDTAKLTINPTLLLPS
                     TGGIGLLPFVFLGLIFIFSGFFYFIHRKKKAGEQR"
     gene            complement(18279..18572)
                     /locus_tag="RD451_002218"
     CDS             complement(18279..18572)
                     /locus_tag="RD451_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HDT7567449.1"
                     /translation="MVYTYTEQEKMKVLDTFMNDGKVKQVPSSTKKKYILLKEVLKRF
                     DHGVTYTETEVNSILLNVFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
     gene            complement(18975..20153)
                     /locus_tag="RD451_002219"
     CDS             complement(18975..20153)
                     /locus_tag="RD451_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDT7567450.1"
                     /translation="MEKTDRFKKQISSTGRITWYFQAYRTTRRGFNSKREAQLAYLEM
                     EKQQRLKKKIVASNDKFSVVGEQWFQYYRSLNEQKEITYDKREEQLKIIVRWIGDKKL
                     SDLTPECLQELLFTLKECGVNGTNVGYAKNSLQSLIQVLNMIFKYCQRKNLISENPMK
                     SVRMPKYQLTVTDLKEAINNIEDKFLTVDELRTFLNYGIVHEELPMSVLFHVLFYTGC
                     RVSEALALQPGDIDFKRNEILFYKQTAVKGKSKDFRIETTKTVSSARRVLVTPLVMEK
                     LQQLIKALGEMRQHYRFIIEETYLFVYLDSSKRGVPYRREYVNDHVKRCVNRSGINKP
                     FHTHLARHTMASLVAEHCSWEVLKDRLGHTDQTTSKIYRHLTSNEKVKPLIAFSSLES
                     "
     gene            complement(20257..20571)
                     /locus_tag="RD451_002220"
     CDS             complement(20257..20571)
                     /locus_tag="RD451_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7567451.1"
                     /translation="MELEVKTNVNSLEIEFYSILQKKLEDYTEKLLAVSHLPLVLTNT
                     DLKRLFQISDSTLNRLVKLGEFPPCWYGIRGHYFRDDVLEWMRKSDSNDYREKLRLLR
                     SL"
     gene            20678..20893
                     /locus_tag="RD451_002221"
     CDS             20678..20893
                     /locus_tag="RD451_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567452.1"
                     /translation="MKQGIADIKIIKEILEKSTANAIAFGTGINLSTVKKLKSGERAE
                     EKLNLADAIKITEFGMKNMPTKIEIWK"
     gene            complement(21193..21435)
                     /locus_tag="RD451_002222"
     CDS             complement(21193..21435)
                     /locus_tag="RD451_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7567453.1"
                     /translation="MKQNKRYIPFIPLTTIKAAASGDSIAMSIVLSKYQNYISRLAMK
                     PVYEEEKGMVMYVDEYMRRQLETKLIEKILEFDTTR"
     gene            complement(21422..21850)
                     /locus_tag="RD451_002223"
     CDS             complement(21422..21850)
                     /locus_tag="RD451_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDT7567454.1"
                     /translation="MGDSEETHIQHTFDSFCKKVVCNEALNIQKKYARFRQRQISMEI
                     LEQKGLGTEFYYLEPNLNSSGTFIVLGMKIFISNEELANAIAALPSQRQEIIFMSFFI
                     GLNDREIGDIIGKSLGSVWYQRQMALEELGKYLGVKYEAK"
BASE COUNT         6454 a         4314 c         3706 g         7450 t
ORIGIN      
        1 ctatcctcct agcaactatt taaataccca aaaaaattac ctctagataa tatcatacct
       61 acgttttcac ttataaattt tttcataaaa aaagcgttta gaggcataat cgttaataca
      121 gatggtaacc aatgtatctg gtttgaactg ggatatcacc ctctccatat atgtattact
      181 aagactaata gatactataa aagacttgat agttttgcat tgattttgcc taatactgag
      241 cataggtgta tgctaaacga tactataagg agtgtgtaca taatgaaaag aattctgttt
      301 atcagtttat caaatttatt gttacttact gcttgtggga cttctgcatc aaagaacata
      361 ccttcagata cgcaaatttc gaatagtatc gattcaacaa tttctacaaa tgagaaaaat
      421 tctccggtag aaacttccga tataaaagtt tctacctctg caaaaaacag ggtaaagaaa
      481 ctgtcagcac gtctccttta tttcaaacaa actctgaatt agcttcttca tcttcttcag
      541 caaataatga tgatagtttc gcgtttactc ctaactaaat gcaaccttta caaatgcttt
      601 acgataacaa gcctgagcta aatgatcctg atatcagttt tgcatttttt gaaatgattg
      661 gatcggatga tctttttaaa actactagtt tgtctatccg aaaataggac agttctggca
      721 gtataggttt ttatcgagtt tctccaccag gcctcgttac agagacagat tctctaggcg
      781 aaccttttga ataaatcaaa aatcatgaac aatcactgcc aactaaataa agtgccttca
      841 aaagcttggt cttctcgctt ttgaaggcac tttatttaaa tctttatgaa actaaagtat
      901 gttcatattt gttgctatag ttatatagat attctgttgt ttccaactca taaacgtgag
      961 tatattttgc cactactttt ccgcattttt ctaatatttc attgcgatcg acgtcatgat
     1021 attcgtctac gcagatcaca acacaatttt ctaatttact gattacttct ccaaccactt
     1081 tttgtttcaa gccaataggt tggcaaatat atttttttcc taaaatgata gtttcgttat
     1141 tcatatttca tccatcctta atgtttttcc attatttaaa atgataatac cattaaaata
     1201 tgattatgaa aatcaataac acttgtgatt ttataaaaaa ataaaaaaac cgaaaaacag
     1261 aaatgcccac tgtctttccg gctcttttta ttcttgattt ctcttctttt ttgtttcaat
     1321 agacgatttt agttattaat aaatgaaaaa gcatttatat taaaatttgc taataaaaga
     1381 tctacatatt tttctagaaa tgcttgatcg atttcatcat accctttcgt tactccgcaa
     1441 tcgatatcta aaacaccgat taaattacct tcttttacca ttggcactac gatttctgat
     1501 tgtgcggctg aatcgcagga aatgtaattt gcatgggttt tgacatcatc aacgatcaat
     1561 gtttcttgtt tttcagctga ttctccacaa actccttttc ccatcttgat acgtgtgcaa
     1621 gaaactcgcc cttggaacgg tcctaaaatc aattcattac catcgaataa ataatatcct
     1681 gcaaagacag tctcaggcaa agtctcattc aacaatgcag atgaatttgc taaatttgct
     1741 aaccagttat cttctgcttc taataatcct tgttgctgta ataataaaat ttcgtatgca
     1801 tcttttttct gtttttctgt ccacatgata aaaaccgctc ctttttgatc tatggagaag
     1861 attatagctc agtttttttg taaacgctag gtttcctcct caaaaaaacg agatacgtca
     1921 ggttaatcac cttgaacgca tctcgctgtc tttttctatt ctgcttgttg gatttctgct
     1981 gctaaatcag cataatcaat cgtttcgtga acaaaagtcg gatcatcaac tggaaaatgc
     2041 tgtacaaggg acgagatgcg gctaatctca acttttcctt cagccacttc aaaatccatt
     2101 acatgtccgc caaatgtatg tgtatcatcg ataaaatgca agtgaaatcc cgctgcagca
     2161 actccttgga ataattcagg cgtaaagaac ccgactaatg ttccttggac attgctttgt
     2221 tggaattctg gttgagactc tgaaattttt gctagtcttc tgtaaggttt ttcttgcttc
     2281 ggcatgatac ggatgtgcat atttttgaat aatccagtta tcttcactgc caaaaatagg
     2341 ttttccccgg cttctcttac taatatgtct tttttcaatt gttctccatc tgcagttttt
     2401 gagacagaaa aactagtatc tggcgtaaaa tctgtaattg ctgcataggg ggtaagttca
     2461 cttccatcta attgggcaac tgagccatct gatcttcctt gataagctac gccatctaaa
     2521 aagatgactt caccatcaag cccatgcaat gttcccaatc ccagagttcc tttttctaat
     2581 atatgagcaa tcgtttctgt tccatccatc aagccagcca tcaaagctcc taatgtcccg
     2641 tgctggtata agattttttc agtcatgtcg acacttcctt aatagaattg atctggtaag
     2701 attgtttctc ccaatttctc attatcacgg taatcaatcg gaatatcaat aattacgggt
     2761 ccttctgtcg caaatccttc ttctaaagct ttttctaatt cctctacact tgtagctcgg
     2821 attcctttag cgccaaaagc ttctgcatat ttcacaaaat caactggacc aaagtctaca
     2881 cctgacgccc gctgatattt cattttttct tggaactcta ccatattgta gtgtccatca
     2941 ttccaaatca aatgaacgat attcaatttt ttacgtaccg ccgtttctaa atcctgggca
     3001 gagaataaaa atcccccatc gccggaaact gatacgattt gtgtatttgg acgcaccaat
     3061 gcagcagaaa tcgcccatgg caatgcaaca ccaagcgttt gcataccatt actgaataac
     3121 aaatgacgag gttcataact tctaaagtgg cgtgccatcc aaatataatg actacctaca
     3181 tctacggtaa cagtcatatc atctgttact tttgactgaa gcgtgttaat aacttctaaa
     3241 ggatgcaaga tacctgcttc tccttttgat tgaacaatgt cccgctccgt taattctgct
     3301 tgaagagatg ctaaatattc ttttgcatct tctgacactt gttgaggctc taatgaacct
     3361 gtcaataaat caagagtggc tgagatatca ccgatcaatt ctctttcagg ctgcataaaa
     3421 ggatcgattt cagctggcgc ttcatcgatc acaatgatcc gcgcatcttt ttccgcattc
     3481 cagtttcttg cttcatattc gattggatca tagccaatag caataactag atcacttcgt
     3541 ttcaaaagca tatctcctgg ttggtttcta aataaaccca cacgaccaaa gaaatgcgct
     3601 tctaattcac gtgagatcac tccagctgct tggaatgtct ctacaacagg caatgctgtc
     3661 tttccaacta attgcctgat ggctaacgtt tctttttcac ttgatcctcg catacctact
     3721 aatagtaccg gtagttttgc ttctctaatg cgttcagcta ggtaacggat atcatctgca
     3781 gaagcagaac ctaatttagg atcgctcaat ggcttgatga cattcccttg gacaggtgca
     3841 tccactacat cttgcgggat actgataaag ctcgcgcctt tttttgaact cttagccata
     3901 cgataagcat tggcaatcac ttctgaaatt gtttctggat cttggatttc tgcactgtat
     3961 tttgtgattg gctggaacag tgctgcatta tccatgcttt gatgggtcaa cttcaataga
     4021 tcgcttcgtt ttacttgtcc ggcaattgct aaaactgggt caccttctgc tgtcgctgtt
     4081 accaaacctg tagctaagtt actagcacca ggaccacttg ttgcgataac tactcctggc
     4141 tctcctgtaa tacgtccgat tgcttgtgcc ataaatgcag cattttgttc gtgacgagtc
     4201 acgattaatt caggaccttg atcctctaat tcattaaata caccatcgat ttttgcacct
     4261 ggtataccga atacataatc aacatgatga ttaatcaaac tttctactac agatttcgaa
     4321 ccttgtttca ttttttcgtc cattgaacat cgtccttttt atgctttatt tttaattatt
     4381 agttagaaat aatcacaaat aattgataca gtttctaaac ctgtttcatt caaaagtata
     4441 gcacgtttta tttcatttgt ttagccatat gtttcaaaaa atgaaaaaga atgacagttt
     4501 ttacataaaa actgtcattc ttaattgaaa gtttcaattt ataaagtcta cagatccata
     4561 gttctcatca atttacgatt gttgaagtaa atcaaaccaa atacgataga aggacctagt
     4621 agaatacacc attggggctt tacgaaaaag aagagaaaca aacttgtcaa tagtaaaaaa
     4681 tctagtaaac tcacatacca ttttttcaac gtatagtaga acgctatccg tagaacttga
     4741 tttggtttcg acgctggatt tctcacctga aaataccagt agttgatgct aaaggaaact
     4801 gataaacaag caagtaaaac aaacaacgga atcaaccatt ttccataaga aaaacgtata
     4861 aaaaagaaac aatcaaaaat cattatcaca ctaactatcc aagcaaatag ccaataaaaa
     4921 aatcccttta gccaaaattg gcgaaacgtc tttatgaaca aacgtactgg tgaaaaactt
     4981 ttttcttttg ctaattcttc tgtcatacct atcatcacga tgcaacctgg accaataaaa
     5041 agtaaagaaa aaataaagga aaagacattc cttccatcta tcgacaaaag gaacgcagct
     5101 gctatataca agatattgac acaccaaaaa caaaggctac ttgccaatga ttgatacaac
     5161 caataaaaga attccatata aacatttttg tcaaaacgct gctctttcat aatcacctcc
     5221 tattccttca ttcctgatga agcgatccct tctacaaaat atttttgcat cgctaaaaat
     5281 ataaaagcaa caggaagaac agaaacaact gaggcagcca tgattaatgc gtactctgca
     5341 tcaaatagcc caataaacat tttcaaccct aactggattg ttttattttc cgtagaagac
     5401 aaataaatga atggccccat ataatcgttc catgtattaa cgaatgtgat gatcgtcaaa
     5461 ctggcaatcg ccggttttgt aagaggtaaa atgatcttgc gatagattcc ccactctgat
     5521 aagccatcga tccgcgcact ctcacataaa gaatctggga tactactgta gtattgcttc
     5581 aacaagaaca caccaaaagc attgaacgct tgtaatagca ccaacgacca caacgtatat
     5641 gttaaaccca cttttctcat cataatgaac tgcgggatca tataagactg ccaagggaca
     5701 gcaatcgtgc cgatatatgc taaaaataaa atatcgcgcc ctttaaaatt tagtttagaa
     5761 aacccgtaag cagcaaaact agaagtaaac aactgaatca acgtgatcac aacgcttaaa
     5821 aaagctgtat tcttaaaaaa tgtcactaaa ggaatacgag accaaataac cagataattc
     5881 tctaaatgcc aagttttagg gatccattga atcggaatcg tgaacacttc attatttgct
     5941 ttgaatgaag cagaaaccat ccataaaaaa ggaatgatcg tcaataaagc taatacaatc
     6001 agcagaatca tacccaacca ttgaataaag ggcatgtttt ttgaacgaat ttttgctttt
     6061 tttctttcat ttcgaacacc tccaaagtta taatcttcat ttctttgtaa tgattacaat
     6121 ccagaacaac ggttattata gctgattcat ttccgttctt cttatgtttg taagcgctta
     6181 tttaacaagt tatgtaaatc tctttatttt ttttgattta aaaatgaaaa aatacaaaag
     6241 caagactgtc atacgtctcg cttttgtatt gaaatttctt cgattagaga tacttattac
     6301 tgttcaaaag cttctttgaa acggtgaatc aattcattga ctacaggtga taaaatccga
     6361 ttctttttcc agactagcat gcagttcgtt tcaatcattg ggtcaagcgg aacgaatgtc
     6421 actcgctttg aaagatgact tacagcacct tctatgacta aagcagcacc tacctgattc
     6481 tcaattagcg caaatacatt gaaaatcaaa ttgtacgttc ctgtgatcag caactgctcc
     6541 ttttttatgc ctaaccagtc agcaaacatt cgctgtattt ctggacgctt tgagatcaaa
     6601 agaggtacat tcgcaaagtc ttcttttgtt atcacgtctt tttttgctaa aacagaattt
     6661 tctaaaatga gcaatcccca tttttccttt cttggtaaca aaatcgtttc gtatttctct
     6721 gtatctactg gatctagcaa aatcgctaaa tctaacaggc ttttttctag tcactccgtg
     6781 atatcatcac ttgttccgct gtggatatga aattgaacgc tgggataatc acggatcaac
     6841 ttttctagta atagtgccaa tgtattcgaa ttatcagctt ccacacagcc gatcgtaaat
     6901 cggccgctga ataattgttt ttttctgttc tcgaattctt gagtggtttg attcgttaaa
     6961 tctaaaattt cttctgctcg gcttttttag aaaataacct gcttctgtca agatcatttt
     7021 gcggttttcg cgtacaaaca gttctgttcc tagttcctct tctaactcct tcagttgtcg
     7081 gcttaaggtt ggttgtgtaa gatgtagaac ttctgcggct tgagagattg ttccttcttc
     7141 tgcaattgtc caaaaatatt ttagtaagcg taactccata gcgatgctcc ttgatttttt
     7201 tacttgatac attccatttt atttctagat aacacacgat catatttctt gatttttcct
     7261 tgtaaacgtt ccaaacactc ttgcatttca gcaatttctt tcgtcaaaag ttcactttct
     7321 tcaatcaaaa gcttacgccg ctcaaataca gttgcttctc cttcgctaga taggcgaata
     7381 tattcaatca aagactcgat cgataatccg gcatttcgca tacagatcgt aaagtcgacc
     7441 cattttaggt cttcttctgt ataatcacgg attccgcctt ttgtccgatt aactggtgga
     7501 atcaacccga ttcgttcata atagcgcaat gtatcggccg aaatgccctt ttcttcactg
     7561 acttgtttga tattcatctg atcactcttt ctcttaattt cttgccactt tacttatgta
     7621 ttttatttat tctacaactt taagtgtact ccaagtcaat actcatttct attaaaacta
     7681 agctggatta tctatatcgg ttgtttgtgt attatttcaa ataaaaaagt cttgtttttt
     7741 tattcttttt tggatatact tttaacaatt tagggaaatt ttaggaaaag gggtataaaa
     7801 atgacaacgt atcagcgaaa ggtattatta tcgacatcgg cgggaattgc tttagagaat
     7861 atggatatta tgtttttagc tttttcatta tcttcaatga ttacttcttt tcatattagt
     7921 ggtacgcaag cgggtttcat ttcaacgatc actaatttgg ggatgctcat tggaggtatt
     7981 ttttttggca tcatagctga taaatatgga cgtgtgaaag tattttctca aacggtcctt
     8041 ctgttttcga ttgcttcttt attgatgtat tttgcttcaa acatctactt ggtttatctc
     8101 tttcgcttta tcgcaggtgt aggagcggga ggagaatacg gggcgtgtat gtccttgatt
     8161 tccgaaagtt tttcaaaaaa acaaattgga cgagcttctt cggttgctgg tattggtgcg
     8221 caggtcggtg cggctttggc tgcgatttta gctgctgtga tcattccaac gtttggttgg
     8281 aagatgttgt atgtcgtagg tgtactgccg gtgttgatgg tcttgttcat tcgtcgcggc
     8341 ttgactgaac caaaggaatt caaatctgta caatctgccg aaaagaaaac caaacttagc
     8401 agactgtttg aatcaaaaca tcttgcttgg caaacatgtg gccttagtat catggtaact
     8461 gtccaaattg ccggctattt tgggttaatg aattggctgc cttcaattat gcaaaatcga
     8521 ttagggcttt cggtttctgg gtcttcattg tggatggtca gtactatttt aggcatgtct
     8581 ttggggatga tgacttttgg cataatcatg gataaattgg ggcctaaact agccttttct
     8641 ttgtttttaa tttgttcatc cttatctgtc tatctacttg tgttagccca tagccagtgg
     8701 agtttggtag cagccgctgt gatagtcggc tactttatca atggcatgta tggtggatat
     8761 ggcgcagtga ttagtagttt gtatccaaca gaaatccgcg cgacggcgaa taatttcatt
     8821 atgaaccttg gacgagctgt tggtggtttt tcttctatcg tcatcggttt cttgatggat
     8881 cattatagtt taactgccgt aatcttgttt ttgagcggta tttacctagt cagtctgctg
     8941 gtcttgacaa ctcttactgg tgttacagca ttaagggaaa gcttgcagca ttgatagttg
     9001 agtctgtaaa tgacaagaaa gaggtgtggc aaaagcttgc atctgcggta ataagaccag
     9061 ccaaatcaaa aacatgagac actgtttccg tttggctggt cgtattactt gatgcagggc
     9121 agctttttca actgctaatt tccttctatc tggcggcgac tattctttga cgtccgtcat
     9181 ttcaaagtac tttactaata acttagcata acgaaaaact gtggatacac tcgtatattg
     9241 agcgtctgca taatcttcca aatttttctc aggatgttga tacatgaatt caatcaaatg
     9301 ataattatat gattttctgt agaaatgaag ataaataatg tagattggga agttctcctg
     9361 cttttccata gaaaagcgcc gattattctc attcttcaaa atgaccttat caggatattt
     9421 ttggaacaat tcttctaaat ctgttagata attcaagata gacttacttg ataccttcaa
     9481 ttcgttttgt agttcttcta ttgaacacca acgttctgtt tcaagcagta aatgaatcat
     9541 tttaattttc ttttgagaaa cttttgttaa aaaagtctgc atattttctc ctcctgtatc
     9601 tactttacta tactacatac aagaaaaaaa acggatacaa atatcatatt gtcacaccgt
     9661 caatagtgca taaacctgtt attatttctc tttttttcct aagtattcta ttgatatgaa
     9721 tcatttaatc gtttattata taaatgtcaa taatctaata ataaaataac gtacatattt
     9781 tattattgca tacttaataa cagaactata gcaaaaaatc ccgtgtatca acacgggatt
     9841 agattaagtt tcctcaatca ctattcataa cacaattatt ataacaagta agtaaacaat
     9901 tgaaaaggac atttattgaa aacggttgtt ttttacttaa ggaggaaatt tagcgaaaaa
     9961 attagttgca ttgtttttgg tcgcaggaag tttgttgagt gggtgtggtg ctactacgtc
    10021 tactactcaa agcacaagtt cagatcaggc ttccagcagc agtaccacga tctccgaaag
    10081 tacggcagat tcatcgaaag aacaagaaca aattgaaaag aaaaaagaag agaaacaaaa
    10141 agcggaaaaa gctgcactag aaaaaaagtg acagaagcgg aatctgcttt gtcacaagct
    10201 gaagcaaatc ctacaaaaga aaactatgca actgcttcag cagctatcca agcgctacct
    10261 gaaaacaaac aagagttgac aagccgtctt gctgcaattg attccacaat caaagcaaaa
    10321 gaagcagaag aagaacggaa aaagcaagaa gaaattgcac gacaacaagc agaacaagcg
    10381 caacaagaag caatcgcaca gcaacaagca gaacaggcga ggcaagaagc aatcgcacag
    10441 caacaagcag aacaggcgcg acagcaatca gcagctgaac aggcctctca gcaggcacaa
    10501 gccgcagctc ctgagcaaaa taatgaacaa actgtctatg tcacaccgac cggttcaaaa
    10561 taccatacac ataaatgtgg aaatggtacg tatacccctg ccactttaag cgaagctcaa
    10621 gctcgtggtt taaccccttg ctccaaatgt tatggaaact aattcaaaag ttatactata
    10681 ataataaaat tcttctgaaa cataaaaaaa tagaagatgg cgttccagat agtaaaccaa
    10741 aaataacagt ttacacgtcc atttcgtcag cttctctctt ttttcattta gtctgttccc
    10801 tctgcttttt tggacatctt cattcattct ttctcaatca aatagtacac ctctttttct
    10861 tttcgcagtt tatatcttcc ttttttcaat ttcattgaaa actgtttcga atgtttatgt
    10921 tttacatgga ttttaagcag gagctcctca tgttgcaagc gatagttcct gccttttaaa
    10981 tcagaaaatc tcactagtcc gtattcatca gaagctttca caaatggaac tttttctcta
    11041 gtaatatagt gtttgccgtt gagcgttttt acagaaaaga ccattccttc gattggtcgt
    11101 ccgtttgtgt tctttacata aaaagataaa ggatagtttc gcttagcgat ggccaaagaa
    11161 tctaaataag cgatgagtag ccaaactaag ccgattgatc caagtagtat accgataaac
    11221 caaataaaaa atttccattt tttccattga tcaattcctt ggatcgcttt ttttgcctct
    11281 tttgcttgat aaggaatacg atgccccgtc acaagcagtc gatgtgtatt gaccatataa
    11341 ggagtacagg taagcaaagt cacgagatct ctgccttttt ggatacccaa agaatctact
    11401 tcatcaggta agaccacttg gattttttct acttgatacg ccaatgtctt tccattgatc
    11461 tggatgaaaa actggtctcc ttttttcaac ttaggcaaat ctgtaaataa ttttgcttct
    11521 gggagtccac gatgcccaga aagaacggca tgggtgtttt tcccgccagt cggataagaa
    11581 ctttcttcca ataatgacgt tcctttttgc aaaaatattt ccgttgtctg atcgaatata
    11641 ggtaagctga cattgatttt tgggatttcg atgactccaa gcatatgttc cataaaaaag
    11701 gcattactag gtaaatcttt taatgctttt gcatcaactg cttggttgaa actgcctatc
    11761 cctggtgata cgttttgctc tgccaactgt tggtttttct ttgtcatttt ttcctgctgt
    11821 ttttttattt cctctgaatt cttattcgat gcttgctttt gataatggat gatcatttgc
    11881 tgggcaagaa aatcattcag tgaatcttct acaaaaggat aagaaaagat cccgatccca
    11941 acgactaaaa tgattgccat gaagatgtcc agtattctta ttctgctttt attcatcatg
    12001 tccacctatt ttctaatatg tatatgaaga ggttgtgaaa tcagcgcctt gacctgagta
    12061 ttagcgaagc aaacggcaaa atagttcctc ctattttgcc gtttgttgag cgaataccaa
    12121 gagaccgacc acttgtcaca acctttctcc ccatttgaat cactatcgtt tatttatcgt
    12181 atgatttttg tttccaatag tttaagcttc tgtttcttga tggcgttttt tgaaatagat
    12241 cactgctcct ccaactaaag cagtacctac caagatgaat acgatgatcc ccataccacc
    12301 agttgaaggc aagattcctt taggttggtt atcgatcgtt gtttcatcag aagttgttgg
    12361 atcatcatct actgtaaatt cagtgtacgc agcttcattc ttaggtaatg cgtagccttc
    12421 tggtgctttt gtttcttgaa ggcagtatgc cccttgtttc agcccttcga ttgaaaattt
    12481 cccttctgaa tcagaaatca atttcacttc ttcccagtca gaacctgtga cttcatctga
    12541 ccaagcatat gggtattctc ctgaggcaag gtttgctatt tttttcatta atttaacagt
    12601 tggatctttt gctcttagaa tagaaaattc tgcatcggct aatttttctt gcgtgttcac
    12661 atcttgtttg atgaagtgga aatcaccgta gttttggaca ttttctacag taatcgtgtt
    12721 atccgtagtt gtattttccc gattgactac accgtttgga ttcccaagat tggcttcatc
    12781 tgcgccatgg atgataccgg ttgtttgttg caattttccg ttttttacta taaaagtagt
    12841 ttctttttgt ggattggtta attgataacc atctggtgct tttgtttcaa ctaaagtata
    12901 attgccgtct attaatccat tgacactgat ggatccttca gtatcagttg tgaatgtcaa
    12961 cgctgactca gcaggatcat agagagcgac accagtgttt tcatcaaaac cggtcacgaa
    13021 ttgattctct gaatttttga tctggaattg cgcccctgct aacttatcta cccctgaaaa
    13081 gttcccagct ttctggattt tgatattgct ttctttgatg acatttttag catataggtg
    13141 aatcgtgtct aaaggtttgt cagggtctag ggtaagctta acacgatatt tggcgacgtt
    13201 tcgacaccgg gctttggtgt ttctacaaag acgtatacag catctttccc atcagattta
    13261 cctggaagag tcaggttagc taatccttca ccagaagtcg ttacacttgc gaagggtgta
    13321 gcgtctgctg gaactgctgt gtctttactt ggatagtacg tagcagtgat gtcatatacg
    13381 ttgaattcaa cgccgttcaa cggttcgcta ttcggaaatg tcaattccgt tccgttgttt
    13441 atttgatttt ctggtgctga agtgaatttc aatttatgca aattaaccgt aacattttct
    13501 ggtgtaggtg atacggctgc agaaacctct gcagttccta ggccgagaac gaaaggaagc
    13561 agcatgatag cagttcctaa aaacgtccat atttttgttt tgatgttttt cattttattt
    13621 ccctcctatt gtttcctttt tgttgttttt tataaaacca agctgtccct gttgaaagga
    13681 ctagcaataa ccctaaaatt gagaaacctc caagcatctc ttcgcttgtt tttggaaagc
    13741 ttcctccatt tttttcattt gatggaccat ttgtctgcat ctgaactggc gtttttccat
    13801 tattcgtcgg atttgctttt ggttcgttga tgatttccaa tggtatagga tgaagcggat
    13861 cataactgcc tttttcaact tcaaagagaa tggttgattg actcaatata tatcctttag
    13921 gcggtttaat ctccactagt tcgtaacttc caaaagacaa tccatggaca gaaaatgttc
    13981 catctttact ggaagtaaaa atcgttgctc ttgaatcatc tttggctacc caatgattta
    14041 tcccgttttc ttgcgctaag tattggtcat tttttttgac tagaaattga gcatctgcta
    14101 gtttttgttt cgtttgccga tccactttga caaattgttt gcctcctgtt tggatggcaa
    14161 gatgtgtttc tactgtttga ttgtcagtcg tcaaacgtac atcgttatca aatgtcgttt
    14221 tttcactgtt ttctttcaat gtcatttggt aacggatcgt taattttttt ccagcaaacg
    14281 aactaagatc ttttccagaa tctgataaga caaaaccatg ttttattttt tgtgtgtgaa
    14341 atgtatgaat cttgtctcca ccaatcaaaa aatcgatcgt ttctggttct agccataact
    14401 gaggatcagc tgtatctttg atcgtatagg ttcctatctc gttgatgttc tcaggaattg
    14461 ttacggtgat gagataaggg actttatccc catctgcaaa atctgtctgc ttattctcta
    14521 ctgtttttgt taatgtgagt gcagcaggta ttttttgttc gctctttgga tacaagtgga
    14581 tggtcgtcaa tttatgatta gatgaatctg tcacaggaag cacaacgaca aatggtgctg
    14641 atttttcttt tacttaatct gaagtcttta tttccgtaaa tcggtaaaca gcgtcacgac
    14701 cttgctcatc tttgtccgat gcactaaaag aagcaatgcc ctcttcctcg tctactgttt
    14761 ttgtcacatt ttctgccagt attttttcac tatcactttt ttgtgctagt tttctttgtg
    14821 cgtcttccac actacttcct tctgaccgca gcttgtaaaa ttcatccgag acatcatata
    14881 tagcgaaagt aacgccgttc aaccctttta ctccttgaaa gttatccggg atatttattc
    14941 cgtcgttttg actgatactt ggcatcttat cgctttcgaa cattcgatta tgcaaagtaa
    15001 atgtaatagg tgattctcta gctgacacag tcggagaacc tataaaaaag accagtagga
    15061 taaaaaagag aacagcaaat atatccacac gtacattttt tgtttttttc atcgctgttc
    15121 acctgctttt ttcttacgat ggataaaata aaagaagcca gaaaaaataa agatcagtcc
    15181 taaaaagaca aagggcagta gacctatccc acctgtcgaa ggaagcaaga gagtcggatt
    15241 gatcgtcaac ttagcggtat ctgttgcgat aatcgtataa ttattgttta cacttccttc
    15301 gcctaaacta atcgttacta tttgtgatcc aatatctgtc cggctgttaa ctgttagggt
    15361 ataatccaat gattcgccta agacaacacc ggtaacgtgg agatttccaa ccgaaatcga
    15421 gtgactttgg gcatcataat taaaggcagc gtcatcgaca gtaatcactg cgttagcttt
    15481 atagatggta taagttcctg atgtgttggc tatatcagta aatgacaact tgggatttgc
    15541 tgctttgact ttgtctattc cgctattcgt tagtttaatt gtatagctgc cagcattaac
    15601 catatttttt gctgattgtg catctgctgt gtaatccata ctgctaagtg ccacttgtac
    15661 tggagtaagc gaactagtga caccctctgc tagcttgaca tggattgacg ggacacctgc
    15721 ttttccatca tatgtcttac tgccactgag ctctaccgca ccgctgattt gcttaatcgt
    15781 atagacatca gatgtctgca cgatagtaaa taaatagttt gttctggcag ctagtttagc
    15841 tagtccgctt tttgtcaatt gccaagacgt ataggttcca atttcagtag gcgcagttac
    15901 ttcaactccc ttttcattca tcgctttgaa atcagttgga ttccatgtga tttgatcaat
    15961 actgagatca ttgtttaaaa gggatgttga ttctgtttta tcattaaagg catatttaac
    16021 gatcggtaca acagaaagac catcatagta cttactgcca tttgcattga ttgatactgt
    16081 tgcatttgtc ttataatata ggatgacttc agaaatctgt tttccatttg cgtcctttac
    16141 gattacattt ccatttgtat ctaaactagc taaaacactc attgctgatt ggttctttgt
    16201 ttctatcgct gaaacagctg taaaggtata tccgttgata gtaggcgtat tagtcgtcag
    16261 gtcttgtgca gcacttccgt aagtaagatt cattatttta gaaggagcaa tcatctgtcc
    16321 aaaatagtct tgatacttaa tagtgattgg tgtttgtttg cctgtatagg tcaccgtatc
    16381 gacgttactt tctagggctg tgaaagaacc gtttgtttgt gcaaaagaat agcccgttac
    16441 tgctgttgga gtgataacca ctttgtcacc cacatggatt ccagataatg tagtcccgta
    16501 cgttccgatt tttgctgctc caccattgac tgtataagaa aaagttcctg tccgattcgc
    16561 attgacctga accgttgctg cttgataggt tggaaaattt gaaacatttc ccttaccatc
    16621 aacgatctgc ccatttttga tcgagtaccc cgtgaatgga atatcatttg ctaactgtat
    16681 accgattgaa aaagtactca tacctcctcc ggcaggaagc cctccccatg ttgagggtgt
    16741 aaaagaataa cttttatccg cattgggtgt aactgaatcg atcgtatttc cagcggtagc
    16801 cacccccata tagatacttt ttgggaatgt gatagtagta ccatttactg tggagccaat
    16861 aaacagatta tggatatctg gacggttatc aataaaagcg attgctttgg ttacgccttg
    16921 taacgcagtt ttatccgcac tcatcgatcc gttaaccgca acaatgactc catctttggc
    16981 atatatcact gtatatccat ctggtatggt atgtccgttg aaattcgcag tggccgcaac
    17041 agtactaaat gtctggcttc tacctgtttc tgaataagct ttctcccctg ctgcttttgc
    17101 tgctgtgatt tctttttctg tcggatcaat cagttgagtc gaggatgtgg ttgaggttgt
    17161 ctcgttgttg ctagactgat tggtgctttc tatggactgt atttcagaat agggtggact
    17221 atttgtctcc tctgtcgttt ggttagcaaa atttgacgtt tctgtataaa cgtttacata
    17281 aatacttgat aagctcccta agaaagtaaa aatcaagatg atcgaaatca taatgggatg
    17341 taagtatttt cttttagata cagctttgag tctagaaaca aaatgttttt gacatatacg
    17401 ttggatttta ttttgagttt tcttaatcat tttcatccct cctctcaata aaaaatcatc
    17461 aaataatcct ttacacgtta ttctaaattt aatttttatt attttattga tgtatagaaa
    17521 gtttggggct ttttttctct ttttattcta aggttatttt agtcttgtcc tttaatacaa
    17581 agattttatt tttaaataaa aaatactctt tttttacgat tattgaaaaa aaaagataaa
    17641 acttgattaa ttgaagtatt gcttaaattt ggaagctatg agggaagaat aaaagagtta
    17701 ggacgggatt atctactatt tttctttgtt ttaaatattt gttatctttg aacataaaag
    17761 agaaatgtgt cgactgcagt gttgtgtccc tcatcacgaa taaacggtgt tcaactagct
    17821 gatcttgtat tcacttaaaa aatggtaaag tacgagttgc tattccccat tttcaatttt
    17881 ctaacgctca ggacaaaata ctgttttcac aacctcattg gaataaaagc atatatattg
    17941 tttcaagaac gaaatcttgt tatcttttta aagggcatct gtccaaaatc taattttagg
    18001 aggtacgttt tggtatttat tcgtacaaat aaaagagaat tatctttatt catgtaacgc
    18061 atccaattga ttttttcatg tacgctcctg gaacgatttt actgacgatt gcttatttaa
    18121 ctgcgaatcg ctcattagct tttatcatag ctatccatat tttgaataac gttcttggct
    18181 ttgtattata gatacagatg acaaaaaaag ttcaagtatg cggtgtagaa ccaatatcgc
    18241 atacttgaac ttttttcaat gagtataaat taaaacttct aattttcaat tcccatcatc
    18301 tgatatgccc gaccgtctga acttcttttg aaaaagccaa atgtgattag ataacgtctt
    18361 tgttcgacat aatcgccact agaaaatacg ttcagcagta tcgaattaac ctctgtttct
    18421 gtataagtca ctccatggtc aaagcgtttc aagacttctt tcaataggat gtatttcttt
    18481 tttgttgaac ttggtacttg ttttactttt ccatcattca tgaatgtgtc taaaactttc
    18541 atcttttctt gctccgtata agtataaacc atcttctttc tccttttgat tctaagaata
    18601 ctccatttat gttagaatat tctggatttt ttattaaagc ggttactctt aagaaagata
    18661 ttatcatagt gctctttttt ttactactac ttataggtag atttattcta atccattatt
    18721 ctcccctacc aataattaaa gaaaaaactg gatcagggtg ttcaaattac atgctaagaa
    18781 aaaagaaccc ttgaatacca agggttcttt ctcagtctga taacaatgat taacgacgga
    18841 tttctttgat acttgtgaaa agtcgttaaa gtattgatat aaaaggattt ttattacctc
    18901 tgactacata ttgactaatt tgttaaaaaa tcgtttttca agaatcctgt aataccagtg
    18961 ctttcaccgt ttttttaact ctctaaagaa ctaaaagcaa tcagaggttt taccttttca
    19021 tttgacgtta agtggcgata aattttcgaa gttgtttggt cagtatggcc taagcgatct
    19081 ttcaagactt cccagctaca gtgttccgct actaagcttg ccattgtatg acgagctaaa
    19141 tgagtatgaa atggcttatt aattcctgag cgattcacgc accgtttgac gtgatcattt
    19201 acatactctc gacgataagg aacaccacgt ttactagaat caagatacac aaacaaatat
    19261 gtttcttcta taataaacct gtaatgttgc ctcatctcac ccaaagcctt aatcaactgt
    19321 tgtagctttt ccataactag aggagttact agaactcgtc tagcagaact aactgtctta
    19381 gtagtttcaa ttcgaaaatc cttactctta cctttaactg ccgtttgctt atagaacaga
    19441 atttcatttc ttttgaaatc tatatctcca ggctgtagag caagcgcctc gctgactcgg
    19501 cagccagtgt aaaatagaac atggaaaagt acagacatcg gtaattcctc atgaacaatg
    19561 ccataattca aaaaagttct caattcatcg acagtaagaa acttgtcctc aatattattt
    19621 atggcttctt ttaaatcagt taccgttaac tgatattttg gcattctcac agacttcatt
    19681 ggattttcac ttatcaaatt ctttctttga caatatttaa aaatcatatt tagaacttga
    19741 ataagtgatt gtaaactatt tttggcatag ccaacatttg ttccattaac gccacattcc
    19801 tttaaggtaa aaagcaattc ttgaaggcac tctggtgtca aatcagacaa ctttttatca
    19861 ccaatccatc gaacaataat ttttaattgt tcctctcgct tatcataggt tatttccttt
    19921 tgttcattta acgaacggta atattggaac cattgctcac ctacaacact aaacttgtca
    19981 ttgcttgcaa caattttttt cttaagcctt tgttgtttct ccatttccag ataagcgagt
    20041 tgcgcctcac gttttgaatt aaagccacgt cttgttgttc gatatgcttg aaagtaccat
    20101 gtgatcctac cagtagaact gatttgcttc ttgaatcgat ctgttttttc catttattga
    20161 ttcctcctat tttgaaggaa cccaacaagc agaaaccctt tggaaatctt tctatctatg
    20221 tcatcattgt accgcatctt agaaagaaaa tgtaacttat aaagatcgaa gtagtcgcaa
    20281 tttttctcga tagtcattcg aatcactctt tctcatccat tctaaaacat catcacgaaa
    20341 atagtgtcct cgaatcccgt accaacaggg aggaaactca ccaagtttta ctaaacggtt
    20401 cagtgtacta tcacttatct gaaatagtcg ctttaaatca gtatttgtta ataccagagg
    20461 taaatgactg actgcaagca atttttccgt gtaatcttcc agtttttttt gtaaaattga
    20521 atagaactct atttccagag aattaacatt tgttttaact tccaactcca tcacccttct
    20581 ctctcaaaat caaaacgacc accacggtac cccttaaaat tgtaaaaaaa cactccagta
    20641 ctccatcaaa acggactaga aaagaggaat ttttaatatg aaacaaggaa ttgcagacat
    20701 aaaaataatt aaagaaattc ttgaaaaatc tacggctaat gcaatagcat tcggaacagg
    20761 aatcaacttg agtacagtaa aaaaacttaa aagtggagag agagctgaag aaaaattaaa
    20821 tcttgccgat gctattaaaa tcacagaatt tggcatgaaa aatatgccaa ccaaaatcga
    20881 aatatggaaa tagtagtttt tctgatctat cagctgtttt gccaaagcac ataggaatct
    20941 cacctccccc cagtaatggc gggccgattt ggttacggaa gtatcattat cgtagtcgcg
    21001 attctcatat taaaatttgt cgcttaaaag ctaaccttgt catggcgtaa ctagagaatc
    21061 aaaatctaca tgtactgata gatttgctat tcatttgtca aagagcgcta ggctattttc
    21121 agcctatgga aatcctttat tttgacccga taaaaaactt ccatagaatg aaaaggaaag
    21181 ggaaaaaata ctttaacgag ttgtatcaaa ttcaagtatc ttctcaatca attttgtttc
    21241 cagttgtcta cgcatatatt catctacata cataaccatt cctttttctt cttcataaac
    21301 tggtttcatg gctaaccgtg aaatataatt ttgatatttt gacagaacga tggacatggc
    21361 aattgaatca ccagaagctg cggctttgat tgtcgttagt ggtatgaatg gtatatatcg
    21421 tttattttgc ttcatatttg acacccaaat actttcctag ctcttccaaa gccatttgtc
    21481 gttggtacca aacactgccg agacttttcc caataatatc gccaatttca cgatcattaa
    21541 gaccgatgaa gaaggacata aaaatgattt cttgtctttg actaggtaat gctgcaatcg
    21601 catttgccaa ctcctcattg gaaataaaga ttttcatacc aaggacaata aaagtaccac
    21661 tactattcaa atttggttcc aaataataga actctgtacc taaccctttt tgttccaata
    21721 tttccattga tatttgccgt tggcgaaatc tagcgtactt cttttgaata tttaacgcct
    21781 cattgcagac tactttctta caaaaactgt caaacgtatg ttgaatgtgg gtttcctctg
    21841 agtcgcccat aatattctcc ccctcaaaaa attcattcaa ctcgttttac ttctatccct
    21901 ttccattatt actacaatct agga
//
LOCUS       DAPBAF010000049        20361 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.049, whole genome shotgun sequence.
ACCESSION   DAPBAF010000049 DAPBAF010000000
VERSION     DAPBAF010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 20361)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20361)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20361
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.049"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            292..1431
                     /locus_tag="RD451_002224"
     CDS             292..1431
                     /locus_tag="RD451_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HDT7567455.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLARHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHSIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
     gene            complement(1498..2073)
                     /locus_tag="RD451_002225"
     CDS             complement(1498..2073)
                     /locus_tag="RD451_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDT7567456.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQVGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
     gene            complement(2078..3052)
                     /locus_tag="RD451_002226"
     CDS             complement(2078..3052)
                     /locus_tag="RD451_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HDT7567457.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPVDIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGLDGLGDTNFPMVLAKQAESL
                     HAVDFLTDYFKEKTDTSVIALGPLTNIASALKNSPSVGKHMDRFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFEKLKQPIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIDESICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFFRKFLTVLLNAQEETIMKDLERLKMG"
     regulatory      complement(3076..3120)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            3335..4303
                     /locus_tag="RD451_002227"
     CDS             3335..4303
                     /locus_tag="RD451_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDT7567458.1"
                     /translation="MVIFYFILILIFIGISYHFLSYFYAKKLVRAGVQRGYDWYEETG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGIPKTIKSYDGLKLAGQMFLQPTQQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLIPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPDASIILHGSSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMIMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMD"
     gene            4416..4694
                     /locus_tag="RD451_002228"
     CDS             4416..4694
                     /locus_tag="RD451_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HDT7567459.1"
                     /translation="MEIKEEKNRLALFNDEQQEIGEMTWSDAGPDIMIIDHTFVDPAY
                     RGQKLAEKLVYTGVELARREGKKIIPSCPYAKKEFEKKPEYHDVLRQS"
     gene            4812..5048
                     /gene="secG"
                     /locus_tag="RD451_002229"
     CDS             4812..5048
                     /gene="secG"
                     /locus_tag="RD451_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HDT7567460.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAVWMILLFVLAFLSSK"
     gene            5151..5906
                     /locus_tag="RD451_002230"
     CDS             5151..5906
                     /locus_tag="RD451_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDT7567461.1"
                     /translation="MKRVKQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKAD
                     YTVYAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFA
                     VRALEEESVIGGGFFCSPLSPVETNVPENFEKYVRQVLKIAGKSEKEINEKAVSYRSL
                     AEHQLMDIQDQAAIAESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQW
                     YPESGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            5909..8266
                     /gene="rnr"
                     /locus_tag="RD451_002231"
     CDS             5909..8266
                     /gene="rnr"
                     /locus_tag="RD451_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HDT7567462.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILVEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSDEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDIVGRRDLRDQLIVTIDGEDA
                     KDLDDAVTVKKLENGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHEIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILEMMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKARNGKSGKRE
                     GKQAGKRSEKNGKKNKRYSDSKQTFGKKKGKKPFYKGVKKKKKKK"
     gene            8288..8752
                     /gene="smpB"
                     /locus_tag="RD451_002232"
     CDS             8288..8752
                     /gene="smpB"
                     /locus_tag="RD451_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HDT7567463.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIVRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            9054..9773
                     /gene="atpB"
                     /locus_tag="RD451_002233"
     CDS             9054..9773
                     /gene="atpB"
                     /locus_tag="RD451_002233"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HDT7567464.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMMTSLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            9826..10041
                     /gene="atpE"
                     /locus_tag="RD451_002234"
     CDS             9826..10041
                     /gene="atpE"
                     /locus_tag="RD451_002234"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HDT7567465.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVIALILVFAV"
     gene            10132..10656
                     /gene="atpF"
                     /locus_tag="RD451_002235"
     CDS             10132..10656
                     /gene="atpF"
                     /locus_tag="RD451_002235"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HDT7567466.1"
                     /translation="MLNQLAIAEVGNAMLGNIIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            10643..11185
                     /locus_tag="RD451_002236"
     CDS             10643..11185
                     /locus_tag="RD451_002236"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HDT7567467.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYEYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMDYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLEKMRNQLNR"
     gene            11208..12764
                     /locus_tag="RD451_002237"
     CDS             11208..12764
                     /locus_tag="RD451_002237"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HDT7567468.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEETLNSAIQEYKDMFLATKGNNSST
                     EDKLKSIQNA"
     gene            12778..13680
                     /locus_tag="RD451_002238"
     CDS             12778..13680
                     /locus_tag="RD451_002238"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HDT7567469.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMYQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            13703..15109
                     /gene="atpD"
                     /locus_tag="RD451_002239"
     CDS             13703..15109
                     /gene="atpD"
                     /locus_tag="RD451_002239"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HDT7567470.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            15123..15545
                     /locus_tag="RD451_002240"
     CDS             15123..15545
                     /locus_tag="RD451_002240"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HDT7567471.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
     gene            16014..16244
                     /locus_tag="RD451_002241"
     CDS             16014..16244
                     /locus_tag="RD451_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HDT7567472.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            16341..17642
                     /gene="murA"
                     /locus_tag="RD451_002242"
     CDS             16341..17642
                     /gene="murA"
                     /locus_tag="RD451_002242"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HDT7567473.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNCPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            17655..17831
                     /locus_tag="RD451_002243"
     CDS             17655..17831
                     /locus_tag="RD451_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HDT7567474.1"
                     /translation="MSNQRYILLTLIKILVVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            17966..18262
                     /gene="yidD"
                     /locus_tag="RD451_002244"
     CDS             17966..18262
                     /gene="yidD"
                     /locus_tag="RD451_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HDT7567475.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFRLTRNKKDKKEPDYKKVVKNTGSTER"
     gene            18326..18709
                     /locus_tag="RD451_002245"
     CDS             18326..18709
                     /locus_tag="RD451_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7567476.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVTPTYQGKGIGGKLLETAFQKLSQLASNQTRIIIRTGTTS
                     SAALHLYQKMGYVEIGRVKDYFIHH"
     gene            18878..19762
                     /locus_tag="RD451_002246"
     CDS             18878..19762
                     /locus_tag="RD451_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HDT7567477.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKTQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLD
                     GDKTFSKLGTAVQMAWRYCERKGLDKNAYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLVGAAANYLAVRQGEN"
     gene            19876..20112
                     /locus_tag="RD451_002247"
     CDS             19876..20112
                     /locus_tag="RD451_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HDT7567478.1"
                     /translation="MMSKKNKDIEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYG
                     PKEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            20200..20280
                     /locus_tag="RD451_002248"
     tRNA            20200..20280
                     /locus_tag="RD451_002248"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:20234..20236,aa:Tyr,seq:gta)
     gene            20287..20358
                     /locus_tag="RD451_002249"
     tRNA            20287..20358
                     /locus_tag="RD451_002249"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:20319..20321,aa:Gln,seq:ttg)
BASE COUNT         6759 a         3566 c         4425 g         5611 t
ORIGIN      
        1 tttttttgca actagcttct gtatatgatg tttacaaaga atggtacaag aaaagatcat
       61 ccttgaaaaa ggaaagctaa caataactag catcatataa gagcttttaa ggatagaaca
      121 gtagaatagg aatctatggg caagtcctct cgtataaata aaataggagg gaagtagcag
      181 catatttttc ataaagtggc tctctttctt catttttact ttggttgctc ctatttgaaa
      241 attcgagcac actcaaatac aataaaaaga aatggcaagg gagaggatta gatgaaaaaa
      301 gaagaaaaaa tcgcgatttt acaagagatt atccgaatta aatcagtgaa tggaaacgaa
      361 ggtgaagtag cagcctattt gaataagctt ttggcaaggc atgacataac aggagagatt
      421 gtttcttaca gagatggtag agataatttg attgctcgtt accaaaaggg ccaatcagga
      481 aaagtgttag gcctatctgg acatatggat gtcgtggcgg ctggtgatga atcgtcttgg
      541 acctatgcac cctttgcagc agaaatccat gggaaccgtt tgtacggacg tggtgctaca
      601 gatatgaaga gtggcttggc agcaatggtg attgccatga tcgaactgaa agagtcagga
      661 aaaccattta acggaacagt caaattatta gccactgtcg gagaagaagt gggtgaacta
      721 ggtggggaac agctcacgaa agcaggctat gtagatgact tagatgcctt gatcatcgga
      781 gagccaacca attacagttt gatgtatacg cacatgggat caatcaacta tacagtcacc
      841 tcgcacggaa aagaagcgca tagctctatg ccagaccaag gttataatgc aatcaatcac
      901 ctaaatgaat tcattacgaa agcaaatgct gaaatgaatc acctcgctga aacaatcgag
      961 aatcctgtcc taggaaaaac aatccataat gttacattga tcagtggcgg gaatcaagtc
     1021 aacagcatcc caagccatgc gcagctccaa gggaacattc gatcgattcc agaataccca
     1081 aatgataaaa tcattgcatt gctgcaatca atcgtcaatg aattgaatca agagacagac
     1141 tatcatttgg aattgatgat cgattacaac aaaatacctg tcaaagctga tccagattct
     1201 cctttgattc attccattca gcaacaattc agccagccat tacctttagt tggagcggca
     1261 gcaacaacgg atgcagccga atttacgaaa gctaaccatt ccttcgactt tgtcgtcttt
     1321 gggcctggtg tcgttacttt gcctcatcaa gtagatgagt atgttgaaat cgataattat
     1381 ttggatatga tcgaaaaata tcaaggaatt attttatcct acttagcgta agattttttt
     1441 aataaatgaa aaaacagagc cagattagca ttattttgct aatccagctc tgtttattca
     1501 gcctattttt ctttttgaat atatcaagcg ttggggcaac atagtgatga ctaatgaaac
     1561 aacgacgata gacaacaagc gatcaaggta gtctgtaccc acctgtacca agatcacact
     1621 tgttgtctga cttaaaccta acccatgtaa tagctgaacg atcatactgg atcctgagga
     1681 ggtgatcccg ccaaataact gaacggtaat gatcgaagaa acgatcgttc caggtaccga
     1741 caaaatcaaa gcgagtaata acagtttcaa gctgttttta tctttgccga gatatcttgg
     1801 caaaatcaat ccagcaagca agcctgtgag aatttggatt ggcgaataat acagagaaaa
     1861 aatatctgta gtcactccac ttaaaatacc gctggacaat cctgtcagca ttccaggtac
     1921 aggcccaagc aatgcaccag caaaaatcgt tccgatagaa tcgagataga ttggcaaacg
     1981 aagccataaa gcaatcgttc ctccaatata attgatccca atacacaaag ccatcactgt
     2041 aagtacgcga gttgccattt tgtttttatt cattttgtta gcccatcttt aacctttcca
     2101 aatctttcat aatcgtttct tcttgtgcat ttaaaagaac ggttaaaaac tttcggaaaa
     2161 aaagacgagt atctactttt gtcataattt tactgttagc aggtttctgc caaaattcat
     2221 aacgatcaac caatgtttgt ccgcgactta ttccttgagt ttctacagca gtgaagcttt
     2281 taaagccttc acagatggac tcatcgataa aataagcaac agctaatgga tcattgatga
     2341 cacatcctaa gattctttct tgtttccagt gaaagtcaaa ataaaaacga gtgatcgctt
     2401 ttagatactc tccctcttca ggattcattt ggcagcaata ttcaaggata gtcggtgtca
     2461 agacgatttc tcttgtcaca tctaacccaa ccatttctat cggttgtttg agcttttcga
     2521 atacataaga agctgcttca ggatcacacc agtaattgta ttcagcaact ggtgaacagt
     2581 taccatggct tttgtaagtt ccgcccattg agacaaaacg atccatatgt ttcccaacag
     2641 atgggctgtt tttcaaagca gaagcgatat tggtcaaagg ccccaaagca atgactgatg
     2701 tatctgtttt ttctttgaaa taatcagtca gaaaatcaac tgcatggagc gattctgcct
     2761 gtttggctaa gaccatcggg aaatttgtgt cccctaatcc atccaaccca tgagtgtctt
     2821 gcgcactaat gaaaggttgc ttcaaaggtt tttccattcc ttgataaaca gggatatcta
     2881 aacgatcaca gcgctccaaa catttcagca cattctgcgt accgatatct acagggacat
     2941 tcccgcaaac gacggtaata gcaactactt cgatatcagg ggatttgaca gctagtgata
     3001 aagctaaagt gtcgtcgatc cctggatcgc aatcaataat tactttacgc attatttcca
     3061 atctcctttc tttagagata cttagttttt tattctggga agtttccgaa ccagtccaag
     3121 acgagtgtct tgtttataat gcacgaaatt agtatactgg cttttattgt gaatgtaaat
     3181 gctctcttac aagtaaatct attgagaaga actttaagta aatgatacaa tgaaaaagaa
     3241 atggaattta cgtgtgccga agaaaaagaa tcctattgat cggtatattg tataataaat
     3301 agattatagt ttggcagaaa gcggcgggtg tacgatggtt attttttatt tcattcttat
     3361 tctgatattt ataggaatca gttaccattt tctttcttat ttttatgcaa agaaattagt
     3421 aagagcgggg gtacagagag gctatgactg gtatgaagaa actgggcacc gcttgatgga
     3481 tcctgctgca gtcacgtcag tagaaaaaaa gcgacaaaaa ttagaagaag agtgtgaaag
     3541 cttctgggaa caaggaatac cgaaaacgat caaaagttat gacgggttga aactagctgg
     3601 acagatgttc ctccaaccaa ctcagcagaa taaatgggtc atttgtgtac atgattatcg
     3661 aagtacaggg aaaagagata tgtctcatat aggtaaaaga tatgcagaga aaggattcaa
     3721 cgttcttata cccgatttac gtgcgcatgg agaaagtgaa ggagaaatca tcggaatggg
     3781 atggctagac cggctagatt taattgcatg gatccaactc atcttagatg aacaaccaga
     3841 tgcatccatt attttgcacg gcagttcgat gggcgcttct actattatga tggcaagtgg
     3901 tgaaaagctt ccatctgcag tcaaaggatt tatcttagac agcggatatg tttctgttta
     3961 tgcggaattt cggtatatgt taagtaaaat cacggtcttt cctaaaaaaa tgatcatgag
     4021 atatgcgaat cactatgctc agaaatacgc aggttattct ttaaagcaag catcagctac
     4081 aagacagctt ggtagtaacc atttgccttt gttagtcatc catggtgaaa gagatcattt
     4141 tgttcctaca gaagcagcat acacgattca aaacgctacg gcaggggata aagcattact
     4201 gcttgttcca gaagcagaac atttggaagc atcgatgaaa gatccgaaaa cctattggac
     4261 agtgattttt tcatttattg aacaaagaat aacgatggat tgattttctc ttcctttttg
     4321 taagcaacac gaggataaat aattgtttat agaccatgag actgttaaaa taaggtagga
     4381 ataaaaaaat atcagttatt tgaggagtgc ggcatatgga aatcaaagag gaaaaaaatc
     4441 gtcttgcttt attcaatgat gagcaacaag aaatcggaga aatgacatgg tcggatgcgg
     4501 ggccagacat catgatcatt gaccatacat ttgtcgatcc agcatatcgt ggtcaaaaat
     4561 tagctgaaaa gctagtgtat actggagtag aactagcaag acgagagggg aaaaagatta
     4621 tcccttcatg cccttacgca aaaaaagagt ttgagaagaa accagagtat catgacgtct
     4681 tacgccaatc ataataataa cagctgaaag atttgcactt tcagctgttt ttccatttat
     4741 atagagttgt cacggagttt tatctatgat aaagttaaag agacgatatc ttttgggaag
     4801 gaggctgcta tatgtataat ttaattttgg gaatcgtgat cgttttatcg attgttatgg
     4861 tcattgcgat tatgatgcag ccaagcaagc aaaatagtgc agcgagtgca tttaccggcg
     4921 gtgcggatca actattcggc aaacaaaaag ctcgcggctt tgaagctgtc atgcagcgat
     4981 caactgcagt catgggagct gtctggatga tcttattatt tgtcctagca tttttatctt
     5041 cgaagtagtc gaataagcct ctcgcacaac ggcgggcggc tttttttatt gcaaagagaa
     5101 cgcttaagaa gaagttatga aagaaactat ggtaaaatga ggcgaaagag gtgaaacgag
     5161 tgaaacaatt accaaaaccc ctttatgcaa aacatggaaa acgagcagtt ttgctgcttc
     5221 atgcgtactc aggaagtcca aatgatgtcc ggatgctcgc acggttttta gaaaaagcag
     5281 attatacagt ctatgcgccg ctatttaaag gacatggaac gatggagcca tatgatatct
     5341 tgcaagaaaa agcagaaagc tggtgggcag atactaaaaa agctatccat tttttacagt
     5401 ctgaacagtt ttctgatatt gccgtattgg gattatcgat gggtggcatc tttgctgtac
     5461 gggcactaga agaagaatca gtaattggcg gcggtttttt ctgttcgccc ctgtctcctg
     5521 tagaaacaaa cgtgcctgaa aattttgaaa aatatgtacg tcaagtgctg aagatagcag
     5581 gcaaatcaga aaaagaaatc aatgaaaaag ctgtgtctta ccgctcgtta gctgaacatc
     5641 aattaatgga tatacaagac caagcagcaa tcgcagaaag tagactatca gatatccaac
     5701 agccaatatt tttagctcaa gctgggaaag atgaaatgat cgacccaaat ggtgtatttg
     5761 aaacggcacg caaattgagc cgccaacgag tgacacttca atggtatcct gaaagcggtc
     5821 atgtgattac agttggcaca gcaagacgcg aattagaaaa agacgtgttg gaatttttag
     5881 aaaaattacc ttggaatgag gaataaatat gacaaaagaa acaataaaag agaaaattct
     5941 ctttttcatg gaaagcagtc gcaaacgtag tttttctatg gaagaaatcg ctgaaggtct
     6001 aggctttcaa aaaagcgatg attttaaatt actagtacaa acgattgctc aaatggaaag
     6061 agaacagagt atcgttttca ataaaaaagg aaaagtcaaa cttcctttaa aaccgatctt
     6121 ggtcgaaggg acatttcggg caaatgaacg aggatttgga tttgtaacga ttgatcccga
     6181 agaagatgat atctatatcc cgaaagaagc gactggcttt gcaatggatg gggataccgt
     6241 agcaattgat atcatgaagc gagcaaatac agatatggat cgcggagcag agggaaaagt
     6301 agtggagatt cgagaccgag cgactactca gttagccgga gaatttgttg cttattcaga
     6361 cgaagagata caggaaacgg atctttatgg tgtggtcatc ccgaaagata gaaagcttaa
     6421 ccaattcaaa gtgtatgcag cggcagaggg agttcgtcca gttgacggaa gtattgtatt
     6481 gatcgaactg acccattacc ctgaaaaagg gtatgcaact agtttagaag ggataatcaa
     6541 gcaagtgatt ggtcataaga atgaccctgg catggatatc ctctcgattg tcgtggctaa
     6601 cggtattcct acaaaatttc ctgatgatgt gttatctgag gcagatgaag ttccagacca
     6661 gatcagcgaa aaggatattg ttggacgcag agatttaaga gatcagctca tcgttacgat
     6721 tgatggagaa gatgcaaaag atctagatga tgcagtgacg gtcaaaaaat tagaaaatgg
     6781 taattatttt cttggagtac acattgcaga tgtatcttac tatgtgacgc aaggcagtca
     6841 actggacaga gaagcatacg aaagaggaac aagtgtctat ttgaccgatc gagtgattcc
     6901 gatgatccca caacgtttat ccaatggtat ctgttcattg aatccccatg ttccacgact
     6961 caccatgagt tgtgaaatgg agatcgatcc aaatggacaa gttgtctctc atgagatttt
     7021 tccaagtgtg atccaaacaa cagaacggat gacctacaca gctgtcaatc aaatcttaga
     7081 agatcaagat gaagaaacga tgcaacgtta tgctcagctc gtgcctatgt tccaagaaat
     7141 gggtgaattg catcgaatcc ttgaaatgat gcgaatcaaa cgtggagcga tttcttttga
     7201 ggatcgtgaa gcgaagatcc ttgttgatgc tgaaggacac ccaaatgata tccagctaag
     7261 aagcagaggg ataggtgaac gcttgatcga atcctttatg cttgctgcca acgaaacggt
     7321 agctgaacat tataataaat taaatcttcc gtttatttat cgaatccatg aacagccaaa
     7381 agaagaaaaa atgcagcgct tctttgattt tgcttcagct ttgggcattc tggtccgagg
     7441 aacgaaagga acgatcacac caaaagattt acagcatgtg atcgaaggag tagaagacaa
     7501 accagaagct gcagttatca atactatgtt gctaagaagc atgcaacaag cacgctattc
     7561 agaagacaat tttgggcatt atggcttagc ggcagattac tacacacact ttacatctcc
     7621 tattcgacgc tatcccgatc taatcgtcca tcgtctgatc cgttcttaca gtgaagataa
     7681 aagtgaaagc aatcaaagtt cgtgggctgc ggaacttcct gaaattgcag atcatagttc
     7741 taagatggaa cgtcgtgcag tagaaacaga acgtgaagta gattccatga agaaagcaga
     7801 attcatgatg gacaaagtgg gagaagaatt cgatgggatc atcagctctg ttgtgaaatt
     7861 cggcctgttt atcgaactgc cgaatacagt agaaggattg atccatatca atgaattgaa
     7921 acaggactac ttccattttg ttgaaaatca tttagctctt gtaggtgaaa gaactggtct
     7981 gacttttaaa atcggacaaa aagtgcgcgt aaaagtagtc aaagctgatc cagatgaacg
     8041 agcagtggat tttgaactcg tttccgcaga agaggtcact gcgttggaac gtccaaaagc
     8101 acgcaatgga aaatctggaa aacgagaagg aaaacaagca ggcaaacgct cagaaaaaaa
     8161 tggcaagaag aacaaacgat atagtgatag taagcaaacg ttcggtaaga aaaaagggaa
     8221 aaagccattt tacaaaggtg tcaaaaagaa gaaaaagaaa aaataaaatg agttggagga
     8281 aacagctatg ccaaaaggcg agggaaaact aattgcacaa aacaagaaag ctcgccatga
     8341 ttattcgatc atcgacacga tggaagcagg gatggtcttg caaggaacgg agatcaagtc
     8401 gatacgaaac agccggatca atctgaaaga tggatttatt cgcgtccgca acggggaagc
     8461 tttcttgcat aatgttcata tcagtcctta tgaacaagga aatattttta atcatgatcc
     8521 gttgcgcacg agaaagttat tattacacaa gaaacaaatc gttcgtcttg aaaacgaatt
     8581 gaaaaacact ggaatcactg ttgttccttt aaaagtctat attcgtaacg gctatgccaa
     8641 ggtattgatt ggtctggcaa aagggaaaaa atcgtatgat aaacgggaag atttgaaacg
     8701 aaaagatatc gatcgacaaa ttgatcgaac attaaaaaat ttctctagat aatttcatta
     8761 tcctttttcg catattcggt gcttttgctt ttacttaatg ataaaatttg ttagcattta
     8821 atctgataaa acatgattat cacaggtttt ttcttagatc aggagcaccg tgcatgggga
     8881 aaaattcgct tcgtttttga ctgaaataaa aaagtgtcta attttcatga aaatgttttg
     8941 aattttctgt ttcatggtgg tatgataccg tgtggttaga aaccgattgg aaaaaaccag
     9001 atacgcacat gaattgattt tatgtgaatt tcggggaaaa gaggtgaaat ggattggatg
     9061 aacgctcgct aacgtttcac attggaccaa tttggtttga tggtacagtt tgtataatgg
     9121 tgttactgac ctgtttgatt gttttcttct tagcttactt ttttacaaga aatcttaagt
     9181 tgaaaccaac aggcaaacaa aatgcgatag aatgggtcat tgattttagt cgaggaatcg
     9241 taacagataa tctgcctaga aaagaattga gcaatttcca tttgttggca tttacattgt
     9301 ttttatttgt ttttgttgca aacaacatag gtttagtaac aaaaatcgtc ttacctaacg
     9361 aaacaacact ttggaaaagc ccgacagcag acccgtttgt tactttaact ttggcattta
     9421 taatgatctt acttactcac ttattcgggg tgaaaaagtt aggcttcaaa ggatatttcg
     9481 taaattcgtt cttgaaaccc tatagtttta tgtttccgat gaaactgatt gaagaattta
     9541 caaacttatt aacacttgct ttacgtcttt atgggaatat ttatgcgggg gaagttttgc
     9601 taaccttgat tgcaaaaatg atgacaagct taggctggtt ctcattacca ttagcaattc
     9661 cattagagat ggtctggatc gcgttctcct tgtttattgg gagcatccaa gcatttgtct
     9721 ttgtcacttt gtcaatggtt tatatgagcc ataagattga agtagaagaa taatactcgg
     9781 ttaaaaaaca aactactatt tatctatttt aggaggaaaa caattatgaa ttatatcgca
     9841 gcagcaatcg caatcatggg agcagcaatc ggagccggtt atggtaacgg tcaagttatc
     9901 tctaaaacaa tcgaatcaat ggctcgccaa cctgaaatgt ctggtcaatt ccgtacaaca
     9961 atgtttatcg gggtagctct agttgaagct gttcctatct taggggtagt tatcgccttg
    10021 attctagttt ttgccgttta attgaatcag tattaaggca gaaacaacat cgtttgttac
    10081 tgctttttta catggaaact agaaatactc caaagaaagg aaggctcgcc tatgctgaat
    10141 caattggcaa ttgcagaagt tggcaatgcg atgttaggta atatcatcgt tgtcagcggc
    10201 tcatttttga tactactggc tctcttgaag cactttgctt ggggaccaat cagcgatatt
    10261 ttgaaaaaac gtgaagacaa gatcgccaat gatttagatt ctgcagaaca atctcgcatc
    10321 aactcagcga aaatggaaca agaacgcgaa caacaattgt tagcctctcg ttctgatgca
    10381 gctgatatca tcaaaaatgc gaaagaaagt ggagaattaa gccgccaaaa tattttgaag
    10441 gatgctcaag aagaagcagc tcgtctaaaa agcaaagccc aagctgatat cactgtagaa
    10501 cgtgattcag cgctgaactc tgtaaaagac gacgttgcag aactctctct tcaaatcgcg
    10561 gaaaaaatct tgaacaaaga attatctcca gaaatgcatg aatcattaat caatcaatac
    10621 attgaaggtc taggttcttc aaatgaaact agataaatat acagtaggaa gacgttacgg
    10681 gaaagcttta tttgaactgg cgatcgattc aaatcaagca gaagaaatct atcaagatct
    10741 cgtaagttta cgtcaaatct atgaacaagt acctggatta gggaatatgt taagtgatgt
    10801 tcgtctagaa cctcatgaaa aacgagaaat catggacaag cttgtcagcg gttatgatgg
    10861 aatcgttaaa aactttttag aagttgttta tgagtataac cgaatggatg accttttgtt
    10921 catgattgaa gaatatgaac gtcgatatga tgaacatcaa gggttactat tgggaagtgt
    10981 cacaacagca gtcccacttt cagacgaaca acgaatacaa ttagaaaaga atgttgcaaa
    11041 aacaatggac tatcaatcag ttgaattaaa acaaatcgtt gattcttcta ttattggtgg
    11101 cgcgattgtt gaagccaacc atcgagtaat cgacggaagc attcgcacgc aattagaaaa
    11161 aatgcgtaat caattaaaca gatagtacaa agaggtaggt gaatcgaatg gccatcaaag
    11221 cagaagaaat tagtgccttg attaaagaac aaattgaaaa ttatcaaaac gtgctttcag
    11281 tcgaagaaat cggtaccgta acttatgtag gtgacgggat cgctcgtgca catggtttag
    11341 aaaacgcgat gagtggtgag ttgcttgaat tttcaaacgg ctcatacgga atggcgcaaa
    11401 acttagagtc aaatgatgta ggtatcatta tccttggcga tttcgagtcc attcgtgaag
    11461 gagataaagt aaaacgaaca ggtaagatca tggaagttcc agttggagag gccttgatcg
    11521 gtcgggtagt caatccgcta ggtcaaccaa tcgacggact aggtgaaatc gttactgaca
    11581 aagctcgtcc agtagaagcg atggcaccag gtgttatgca acgtaaatct gttaacgaac
    11641 caatgcaaac agggctaaaa gcgatcgacg cccttgtgcc aatcggacgc ggacaacgtg
    11701 aattagtcat cggtgaccgt aaaacaggga aaacttctat tgcgattgat acgatcatca
    11761 accaaaaagg tcaagatatg atctgtatct atgtagcaat cggacaaaaa gattctacag
    11821 ttcgtacaca agttgaaaca ttgaaaaaat atggcgcaat ggattacaca atcgttgtga
    11881 atgccggtgc gtctcaacca gcaccattac tttatatcgc accatatgct ggtactgcaa
    11941 tgggtgaaga attcatgtac aacggtaaac atgtattgat catttttgat gatctttcaa
    12001 aacaagctgt tgcttatcgt gaactttcct tgctacttcg ccgtccacca ggtcgtgaag
    12061 cttatcctgg ggatgttttc tacttgcact cacgtttatt agaacgtgca gcaaaattaa
    12121 gtgatgatct aggcggcggt tcaatgactg ctttgccatt tgttgaaaca caagctggag
    12181 atatctctgc ttatatccca acaaacgtta tctcaatcac tgacggacaa atcttcttag
    12241 aaagcgactt gttctacgcg ggtactcgtc cagcggttga tgccggacta tctgtctctc
    12301 gtgtaggggg ttctgcgcaa atcaaagcaa tgaaaaaagt tgctgggact ttacgtctag
    12361 acttagcaag ttatcgtgaa ttagaagcat ttacacaatt cggttctgat ttggatgcgg
    12421 caacacaagc aaaactaaat cgtggacgcc gtacagtaga aatcttgaaa caaaaactgc
    12481 atgcaccgct agctgttgag aaacaagtag tgattttgta tgccttgaca catggattct
    12541 tggacagtat ccctgtagac agtattttag acttcgaaca tgaattattc gaatatctgg
    12601 ataccaatca ttcagatatt tttgaaacaa tccgtacaac aaaagatctt ccagaagaag
    12661 aaacgttgaa cagtgcgatt caggaatata aagacatgtt cttagctaca aaaggaaata
    12721 attcctctac agaagataaa ttgaaatcca ttcaaaatgc atagtgaggt gagatgaatg
    12781 ggtgcttcat taaatgaaat caagacacgt atcgcttcaa cgaaaaaaac gagccaaatc
    12841 acgcgggcaa tgcagatggt gtctgcttct aagttgacaa aatctgaagc ttcttcacag
    12901 aagtttcagg tttatgcaac aaaagtaaga gaaatcgtta cgcatttgac tgctactcag
    12961 ttaaatgata ttgcctcaga aaatcctaga ggggatatca attacaacag catgctgctc
    13021 agccgtcctg tgaagaaaac cggttatatc gtcatcactg cagatggcgg tctggtcggt
    13081 ggatataaca gttcgatatt gaaacaaacg atgtctattt tagaagaaga ccaccaatca
    13141 cccgatgatt acgtgatgat cgcaattggc ggaactggtg cagacttctt taaagcacgc
    13201 ggtatcaacc tagcatatga gctgcgcaat ttatctgatc agccaagctt tgatgaagtc
    13261 cgcaaaatcg taaatatggc aacaactatg taccaaaacg aagtattcga tgaattatac
    13321 gtatgttata accatcatat caattcgcta actagtcagt ttcgtgtaga aaaaatgctg
    13381 ccaatctcag acttagatcc agaagaagca acgactttcg aacaagaata tatttttgaa
    13441 ccttcaaaag aagaaatctt gtctcagtta ttgcctcagt atgctgaaag tttgatctac
    13501 ggtgcgatcg ttgacgccaa aacagcagaa catgctgctg gtatgacagc aatgaaaaca
    13561 gcaactgata atgctgctaa tatcattgat gagctgacgg tttcttataa ccgtgcaaga
    13621 caaggggcta ttacccaaga aattaccgaa attgttgccg gagcttcggc actagaatag
    13681 tattgagatt ggaggaaaaa agatgagttc aggcaagatt gttcaagtaa tcggtcccgt
    13741 tgtcgacgtg gaattttctt tagaccaatc cttaccagat atcaacaacg cattagttgt
    13801 ttataaaaat gacgaaaata aatcaaaagt tgttcttgaa gcagcgttag aattagggga
    13861 cggagtgatc cggaccattg cgatggaatc aacagatggt ttacaaagag gaatggaagt
    13921 cattgataca ggcaaagcaa tctctgttcc tgtaggtaaa gaaacattag gtcgcgtatt
    13981 caacgtacta ggagatacga tcgatttaga aacacctttc ccagaagatg cggaaagaag
    14041 cgaaattcat aaaaaagcac cagcctttga cgaattaagt acaagtacag aaattttgga
    14101 aacagggatc aaagttatcg atttgcttgc cccatattta aaaggtggga aagtcggact
    14161 attcggtggt gccggtgttg gtaaaaccgt actgatccaa gaactgatcc ataatatcgc
    14221 ccaagaacat ggtggtattt ctgtatttac cggtgtaggt gaacgtactc gtgaaggtaa
    14281 tgacttgtat tatgaaatga aagattcagg agttatcgaa aaaacagcca tggtgttcgg
    14341 acaaatgaac gaaccaccag gtgcacgtat gcgtgttgct ttgactggtt tgacgattgc
    14401 ggaatatttc cgtgatgtag aaggtcaaga tgtactgttg tttatcgaca acattttccg
    14461 tttcactcaa gctggatctg aagtatcagc cttgttagga cggatgcctt ctgcggttgg
    14521 ttatcaacca acattggcaa cagaaatggg tcaattgcaa gaacgtatca catctacgaa
    14581 aaaaggttcg atcacatcga tccaagcaat ctatgtgcca gccgatgact acactgaccc
    14641 ggcgccggca acagcattcg cccatttgga tgcgacaacc aacttggaac gtaaattaac
    14701 agaacaaggg atttatccag cggtagatcc attggcttct tcttcaagtg ctttagcacc
    14761 tgaaatcgtg ggagaagaac attataaagt agcaacagaa gtccaacacg tattgcaacg
    14821 atatcgtgaa ttacaagata tcattgctat cttaggtatg gatgaattat ccgatcaaga
    14881 aaaagtgtta gtttctcgtg cccgcagagt ccaattcttc ttgtcacaaa actttaacgt
    14941 ggctgaacaa tttactggtc ttccaggttc atatgtccct gtagaagaaa cagtgaaagg
    15001 attccgcgaa atcttggaag gcaaatacga tgatcttcct gaagaagctt tccgaagtgt
    15061 tggccgaatc gaagacgtcg tagaaaaagc gaaaacacta ggctactaga aaggggtgcc
    15121 ccatggatca atatttaaca gtaaatgtgg taactcctgc cggtttggtc tatgatcacc
    15181 atgcagctat cgtcgttgca cgtacgacag ctggtgagct tgggattttg cctaaacatg
    15241 caccaatcat cgttccattg acgattgatg aagttcgtgt aaaacgaaca gattcagata
    15301 cccacgtcga ttggatcgct gttaatggcg gaatcatgga agttcgtgat aatgttgttt
    15361 caatcgttgc tgatagtgcg gaacgtgaac gtgatatcga tgtatctcgt gcggaacgtg
    15421 caaaacaacg cgcagaacgc caaatcgaag aagcaaaagc aaaacaagat acgaacgaat
    15481 tgaaacgggc aactgttgcg ttgcaccgag caatcaatcg tatcaaagta tctaagcact
    15541 cataaaatga gatgcggatg tttatccgtg tttaagaaca gtaaaaagag gttatgacag
    15601 aagtggtcag cttcaagaca taagaaggaa tttacgaaaa ttgcttctca aatttttgtg
    15661 aaatctcagc ttatttttcg aagaagctac ttctggaaca ccgtatatca gaggttgtga
    15721 aatcagcgtt ttgtcctgag tattagagaa acaaatggaa aatagttcct catattttgc
    15781 cgttttttga gctaataccg agggtcagat gattgaacac cgtttatttg gaataaggga
    15841 ctgcgacaag acttttgtct cagtcccttt ttttgcatat ttttagcatt tatttcctaa
    15901 aaaatgtaag gggattccta tatttttaag tatacttgtt tttcctttta tacattttat
    15961 ggtattatca ttttattagt tattataaaa caatcgttag aaaggacgtc attatgcaag
    16021 tatacggaat tgatgcggtg cttcgaatcg tgagtcattt ggcgtttatc tacttagcct
    16081 tctggtcttt acgttcgtta cgcattgaaa cttttttcag accaatgcat aatacgcaaa
    16141 ttagaatggc aatcgtactt ttttcaattt ttttagggta cactgcaagt aattttttct
    16201 tagaagttat cgctttatgc cgaaatcttt tcgttagcct gtaaatttta aaaaaaggta
    16261 ctattttaaa agcaaggatg ttataataga aaagattttg agtaagtgta tgctcattgg
    16321 aattttttgg agggaacaac atggaagaga tcatcgtaag aggtggcaat caattaaatg
    16381 gaacagtaag aattgaagga gctaaaaatg ctgttttgcc tattttagct gctagtttgt
    16441 tagcagaaga aggtattacg acattagaca acgttccgat tctttctgat gtcttcacta
    16501 tgaatcaagt gattcgtcac ttaaacgtag atgtagattt tgatgaacaa aagaatcaag
    16561 taacaatcga cgcttcaaga caattagaaa tcgaagcgcc ttatgagtat gttagtcaaa
    16621 tgcgtgcttc aatcgttgtg atgggtccgc tacttgccag aaatggacat gcaaaagtag
    16681 ctatgcctgg tggatgtgcg attggtaaac gaccaatcga tttgcattta aaaggatttc
    16741 aagctttagg agcaaaaatt attcaaaaaa acggctatat cgaagcaatt gcggatgaat
    16801 tgatcggtaa cacgatttat ttagatttcc ctagtgtggg tgctactcaa aatatcatga
    16861 tggctgccgt aaaagcaaaa ggaacaacca tcattgaaaa cgtagctcgc gaaccagaaa
    16921 tcgttgattt agcaaacatt ttgaataaaa tgggcgctca agtctatgga gctggtactg
    16981 aaacaatgcg tattgaaggc gtggatcatt tacatgcagt caaccactca atcgtacaag
    17041 atcgtatcga agcaggtacc tttatggttg ctgctgcaat gacacaaggc aatgtgctga
    17101 ttgcagatgc tatctctgaa cataactgcc cattgatttc taaattgatc gaaatgggtg
    17161 cagaaatcat tgaagaagaa ggcggagtcc gtgtcatcgg accaaaacat atcttaccta
    17221 cagatgtaaa aacgatgcct catcctggtt tccctacaga tatgcaagct caaatgacag
    17281 ctatccaatt agttgcagaa ggtacaagtg tggtgactga aacagtgttt gaaaatcgtt
    17341 tccaacattt agaagagatg cgccgtatga acgctcatgt caaaatcgac ggaaatgtag
    17401 caatcatgga tggaaaccat gaattgcaag gtgcagaagt atatgcaaca gacttgcggg
    17461 cagcagcagc attagtttta gctggcttga aagcaaatgg aatcacacgt gtgcgtaact
    17521 tgaattatct agaccgtgga tattataatt tccatatcaa actacagcaa ttaggtgcag
    17581 acgtcgaacg tgtagacatg gatcaaactt ctgctgaaaa aacagcacaa acgattgctt
    17641 aaggaagtgg ctgaatgagt aaccaacgat atatcttatt aactttgata aagattttag
    17701 tggtgatctt attgcttatc cttctttttg tggccggaac gatgatcgga tatggtgtca
    17761 tcggtggcgg caatccattt aaagtattcc agccaagttt gtggattcat attcgagact
    17821 tttttcattg ataaataaga atcacagtgg ttctagtcga tatgaagtga gccatgaagc
    17881 agaacatgat aaaagaaaac agaagggaac gttgacgtta gtcgcgatcc ctttttttag
    17941 taaaagaaaa gaaggaatct aattgatgaa gaagatattg atttatttag ttagaggata
    18001 tcagcgcttt atttcgcctg catttccacc tagctgccgt tattacccaa cctgttccaa
    18061 ttatatgata aaagcaattc aaacccatgg tgcgctaaaa gggacggtaa tggggactgc
    18121 acggatctta cgctgtcatc cttttgtcaa aggcggtatc gattatgtac cattgacatt
    18181 ccgattaacg cgaaataaga aagataaaaa agaaccagat tataaaaagg ttgtgaaaaa
    18241 tacgggtagc actgagcgat aaagaaaaag aggaaattta ttgtcaaagt aacaactccg
    18301 caactactta tatgggggac aaaaaatgat cgaagaacta aacaagaaag atttaccatg
    18361 gtccttgtta ttagatgcag atcctgataa agaaaaagtt caagtatatg tttccagagg
    18421 gagtggctgg atatggaaag aaaaagaaaa aacaataggt gtactgatct atgtggcaag
    18481 ggaaaaagaa tacgaaatcg tcaatgtagc agtaacccca acgtatcaag gaaaggggat
    18541 tggcggaaaa ttacttgaga cagcttttca gaagctttca cagctagctt caaaccaaac
    18601 tcggatcatt atacgtactg gcactactag tagcgctgcg ttacacctct atcaaaaaat
    18661 gggctatgtg gagattggtc gagtcaaaga ctattttatc catcattaat ctgagcccat
    18721 ttttgaaaat ggagatcaat taagggatca agtgatttta gcaattcact tacctaaaaa
    18781 tagctttaac taataaactt tcaattcgag aaaatgcttt caaatgctaa atagatacat
    18841 tacaatagct ttagcaaaca aaaaggagaa tatttttatg ggaatattag tttttgattt
    18901 tggtggatcg gctgtcaaat atggttgttg ggatggcaaa gagattaaag gtaagggaca
    18961 atttgcaacg cctgaatctt gggaagaaat gaaaacgcaa ttatttcaag tttataaaaa
    19021 aatactcgtt tcttttgaag tcgaaggaat tggaatcagc tctcctggag tagtgaataa
    19081 tgagaaacag gtgattgagg gaatcagtgc gattccttat attcatggat ttaatatttt
    19141 ccgagatttg gaaactctgt ttcaactccc agtaacgatt gaaaatgacg ccaactgtgc
    19201 cggaatggct gaattttatg aaggtgctgc ccgtgattat caagatgttg cttttgttgt
    19261 ggcaggaact gggattggcg gggcgttgtt cacgaaagga caaataaata aaggggcaca
    19321 tctttacggt ggagaatttg ggttgatgtt cttagatggc gataagacat tcagtaaact
    19381 tggtacagcg gtacagatgg cttggcgtta ttgtgaacgc aaaggtctcg ataaaaatgc
    19441 ttataccgga aaagatgtct ttgaattagc agaaactgga gatgcaatag caaaagaaga
    19501 agttgagagt ttttatacgt atcttacaaa gggattattc agtattcaat tttcgtttga
    19561 tccagaagtg atcgtattag gcggcggggt ttctgcaaaa gaagggctca ttgatgagat
    19621 caaaagccga atgaagaagc tgacagaaca attcgatctg catgatttcg aaccgcagat
    19681 tttattatgt gagtacagaa acgatgctaa tcttgtaggt gcagcagcaa actatctcgc
    19741 tgtacgtcaa ggagagaatt aagagcttta gagaaggtgc agcttgcata aaagaagaga
    19801 atgaaatgaa taggagattt ttacctaagg aatgttttat ttgctgcagt atgataaaat
    19861 atctgagagg tgaaaatgat gtcaaaaaaa aataaagata ttgaagtgcg tatagaagaa
    19921 gtgaaaaaag atatcaaagg taagaattat gaagtcactc agttatttat agggaaaaaa
    19981 atgattggtg agatcttagc ctatgggcca aaagaatatg aaattttctt tggtgaagaa
    20041 gattttggaa aagaaaaaag tcttgaaaat gcgatagaaa cagtgattcg acactggaat
    20101 ctgcacgaat aaaaaaatat caaaaaaact ttcaataaag ggttgcaaaa atctggaaaa
    20161 ttaggtatta taactaagtc aggttgatac aaacctttcg gaggagtagc gaagtggcta
    20221 aacgcgacgg actgtaaatc cgttccttag ggttcagtgg ttcgaatcca ctctcctcca
    20281 tttcattggg gtatagccaa gcggtaaggc aagggacttt gactccctca tgcgttggtt
    20341 cgaatccagc taccccagta t
//
LOCUS       DAPBAF010000050        18956 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.050, whole genome shotgun sequence.
ACCESSION   DAPBAF010000050 DAPBAF010000000
VERSION     DAPBAF010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 18956)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18956)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18956
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.050"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(<1..563)
                     /locus_tag="RD451_002250"
     CDS             complement(<1..563)
                     /locus_tag="RD451_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF443 family protein"
                     /protein_id="HDT7567479.1"
                     /translation="METVRLWIFMKNFRSALRYVILESKSGYYLIDTDHYTFWGGYLF
                     PIFNWIIPHKVMKINLPAEEINRLILNKDLQRKREKEHSNVAWIGPAFAVVTSSIVGP
                     MLESIYSDFSIGIRYLFVTLSIAVLLCIKGYVSKKNKDILTLIGVNNLSSTKIILFPE
                     SIKEGSRLLIIFIMLILFSVLFGVMFI"
     gene            complement(750..1400)
                     /locus_tag="RD451_002251"
     CDS             complement(750..1400)
                     /locus_tag="RD451_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567480.1"
                     /translation="MFIKGGQKMCFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLR
                     AGLITFISIVGFFLFTVIVFIWRTTAPPLPEITYGEFPFSLEYEIDEERILIEDTVIA
                     EFIGSFRGNVTTQPRRSWSIKLLNNSGELKAFHYEFLIIESEDVTITLSSGSAGYFMN
                     DGGSKPQLTVRDRIAGFMHFSHYDLEEARKILAEYGITLINWEYAPPIRNFFNDYY"
     gene            complement(1943..2878)
                     /gene="whiA"
                     /locus_tag="RD451_002252"
     CDS             complement(1943..2878)
                     /gene="whiA"
                     /locus_tag="RD451_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HDT7567481.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            complement(2912..3910)
                     /locus_tag="RD451_002253"
     CDS             complement(2912..3910)
                     /locus_tag="RD451_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HDT7567482.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAINR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            complement(3907..4791)
                     /gene="rapZ"
                     /locus_tag="RD451_002254"
     CDS             complement(3907..4791)
                     /gene="rapZ"
                     /locus_tag="RD451_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HDT7567483.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            complement(4926..5657)
                     /locus_tag="RD451_002255"
     CDS             complement(4926..5657)
                     /locus_tag="RD451_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HDT7567484.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLRPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTALQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSEALDTASEK"
     gene            complement(5661..6926)
                     /locus_tag="RD451_002256"
     CDS             complement(5661..6926)
                     /locus_tag="RD451_002256"
                     /EC_number="6.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HDT7567485.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            complement(7189..10005)
                     /gene="uvrA"
                     /locus_tag="RD451_002257"
     CDS             complement(7189..10005)
                     /gene="uvrA"
                     /locus_tag="RD451_002257"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HDT7567486.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQEIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            complement(10015..12009)
                     /gene="uvrB"
                     /locus_tag="RD451_002258"
     CDS             complement(10015..12009)
                     /gene="uvrB"
                     /locus_tag="RD451_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HDT7567487.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKEELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQIRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKDAAKALDFETAANVRDMILELKASK"
     gene            12268..13770
                     /locus_tag="RD451_002259"
     CDS             12268..13770
                     /locus_tag="RD451_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HDT7567488.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            13772..14509
                     /locus_tag="RD451_002260"
     CDS             13772..14509
                     /locus_tag="RD451_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HDT7567489.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(14680..15873)
                     /locus_tag="RD451_002261"
     CDS             complement(14680..15873)
                     /locus_tag="RD451_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDT7567490.1"
                     /translation="MKEKRRDNKGRILHTGESQRTDRKYLYKYVDAFGNTKYVYAWRL
                     TPTDPTPKGKREKPSLRELEQQIRRDIEDGIDSTGKKMTLCQLYAKQNAQRANVKKST
                     QKQREQLMRLLKEDKLGARSIDTIKPSDAKEWALRMKDKGFSYNTINNHKRSLKASFY
                     IAIQDDYVRKNPFDFKLSEVLENDTKKKVALTEEQEQALLSFIKTDNVYHKHYDDVLI
                     LLKTGLRISELCGLTVADIDFKNEVVIIDHQLLKSKEQGYYIETPKTKSGIRQVPLSK
                     ETIQAFQQVMKKRPKAEPFVIDGRGNFLFVNHKGKPKVAIDYNALFIRMVKKYNKHHK
                     DNPLPHITPHTLRHTFCTRLANKNMNPKDLQYIMGHSNISITMNWYAHASIDTAKSEV
                     QRLIA"
     gene            complement(15952..16158)
                     /locus_tag="RD451_002262"
     CDS             complement(15952..16158)
                     /locus_tag="RD451_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HDT7567491.1"
                     /translation="MSNAQDIPVWEKYTLTIEEASKYFRIGENKLRRLAEENKDAGWL
                     IMNGNRIQIKRRQFEQVIDKLDAI"
     gene            complement(16151..17293)
                     /locus_tag="RD451_002263"
     CDS             complement(16151..17293)
                     /locus_tag="RD451_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HDT7567492.1"
                     /translation="MNNLEFALEMKNKRLASGLSQGELASLTHVSRYSINRFENGKAN
                     ASKETQNIILRCLNYYICDKPFYLLVDYLSVRYPTTDALEIIRKVLGMKADYFIHYDY
                     GYYGYKEHYAYGEIKVMASDDEHMGVFLELKGAGSRNMEYVLQAQNRDWYSFLNRCLD
                     CDGVIRRFDLAINDMCGLLDIPVLSEKYRNGGADCRCKNYENVQGGKLSGKNRNLAST
                     LYIGSKASTKYFCLYEKQKEQATKKKHTDIINRFEIRLRGTKAVQAVEELLLTYNPHG
                     LVFYLITDFVQFPDYPLWEIFISHDSLPFEMNPVPVNMERTLQWLERQVMPSIVMIEE
                     IDRLTGSNYMKMIDECTHLSEKQEMLVEQMCTDIADVIESEGVFYE"
     gene            17805..18440
                     /locus_tag="RD451_002264"
     CDS             17805..18440
                     /locus_tag="RD451_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7567493.1"
                     /translation="MEGYAMKISHLGNNIQTIRKFRGMKQQELADKIGINMQSLSKIE
                     RGLNYPAYETLEKIMEVLDVTPNELLSGEWKYVNQSEKEVCQFLRAEERLNAELKHGH
                     YDNFFDSEEEWLEYELEKLREYITDYINGKSIEASDLYPIKEFIQHLKFQKLLDRYDD
                     LYSMDMFGESIEGHKYKTPYQVVKMINPNSKEDMELLREVLRNNNFDDEDE"
     gene            18594..18671
                     /locus_tag="RD451_002265"
                     /pseudo
     CDS             18594..18671
                     /locus_tag="RD451_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
BASE COUNT         5484 a         3983 c         3312 g         6177 t
ORIGIN      
        1 tctataaaca tcaccccaaa taaaacagaa aacagtataa gcattataaa aattatcaac
       61 aaccttgatc cttcttttat agattcagga aacagtataa ttttagtact agataaattg
      121 tttacaccga ttagtgttaa aatatcttta ttcttcttgc taacataacc ctttatgcac
      181 aaaagaacag ctatacttaa agtaacaaat aaataacgta ttccaataga aaaatcacta
      241 taaatactct ctagcatagg accgacaatt gaagaagtca ctactgcaaa tgctggacct
      301 atccaagcaa cattagaatg ttctttctct cttttccttt gtaaatcttt gttgagtatt
      361 aatctattta tttcttctgc aggcaagtta attttcataa ccttatgggg gattatccaa
      421 ttaaaaatcg gaaaaaggta gcctccccaa aaagtatagt gatctgtgtc aatcagataa
      481 taacctgatt ttgattccag aataacatat ctcaaagccg aacgaaaatt tttcatgaat
      541 atccataatc tcactgtttc cacacctaat tcctccaatt ccaattaaat ggatttatag
      601 catcaccaat tatgttaact gcctgaccaa cctcattgat aaaattggca ccactatccc
      661 atgcttcaac aatgctatat atctatcaaa caaaaaatgg aaaactaaat actcgcgcac
      721 ataaatttta cattctgttt tttataagac taataataat cattgaaaaa atttcttatc
      781 ggtggcgcat attcccaatt gattaatgtg atcccatatt ctgcaagtat tttacgagct
      841 tcttctaagt catagtgaga aaaatgcata aaacctgcaa tacgatcacg gactgtgagc
      901 tgtggcttgc ttccaccatc attcataaaa tatccagcag agccactact taaagtgatt
      961 gttacatctt cactttctat tattaagaat tcataatgaa atgctttcaa ctctccacta
     1021 ttatttaaaa gttttatact ccaacttcgt ctaggttgag ttgtcacatt ccctctaaaa
     1081 cttcctataa attctgcaat caccgtatct tcaatcaaaa ttctttcctc atctatttca
     1141 tattcaagac taaacggaaa ttctccatat gtaatctctg gcaatggtgg tgctgtagtt
     1201 ctccaaataa atacaataac tgtgaataga aaaaatccaa cgatcgatat aaatgttatg
     1261 agacctgctc gaagtaaaac ccgatataat aaaaatgctg tatttcgctt tgctatatct
     1321 agaaaaataa aaagtactgc aatcataatg atagtaaaag ttgtaaaaaa gcacattttt
     1381 tgccctccct ttataaacat cgattctcaa attctaaacc aaatcttgat agttcaagtt
     1441 caggtataac gtataccaac catacatccc aattactatt tatgaactta tgattatcac
     1501 tgaataaatc actccatccc cttgttaaaa cttctacatt aattacacct ggttgttttc
     1561 gactagctaa tccaatgaac ttatcaacca tccttatcca ccaaccacga gaatcttgac
     1621 cagaagtaag aaaaacagtt ctcaaggttg atcgagcagt tccttccagt ttttaattaa
     1681 tctccagtta tagataaata cttgatccta tctatatcag gacttctata ttaagcaaaa
     1741 gtttatgtat aaaactaaaa tcttcattca gttgtctccc cgctttttat acgattgtat
     1801 taaaaaacaa tagaagcctt tcaacattat gttactccag taaagttgga attatagttt
     1861 gacggaagaa aagcaagtat agcttttaaa aaaaactgat acattcgcat ctcctgcttc
     1921 atgtatcagt tttttctttg gattaaactg cttcttcacg cagtttttcc gcaaattcat
     1981 ttattttgcg aattcggtga ttaattcccg attttgatat tgcacctgag ggaatcattt
     2041 cccctaattc tttcaagctg acctctggat gttgaagccg aagttctgcg atttcctgaa
     2101 gtttttcagg aagggcatgt agaccgacct ttgcttcgat caattcgatg ttttcgattt
     2161 gtttagaagc cgcatcaatc gtcttgttca gatttgctgt ctcacaattg actagacgat
     2221 tgaccgaatt tctcatatcc cgtacgattc gaacatcttc aaatcggagc attgagttgg
     2281 ttgcaccaat caatgttaag aaatcagcaa ttttttctgc tccttttaaa tacgaaatat
     2341 agccattgcg ccgttcaagc gttcgagcat gtagaccgta ataatttaac atatcgcaaa
     2401 tgtcttggtt atgctgttca taaatagaaa atatttccaa atgataacga ctcgtttccg
     2461 gattattgac tgaacctgag gccataaaag caccacgtaa gtaagaacgc attttttgcg
     2521 aatttcccat aatctcgtcc gaaacgtgtc cattgaacat cataccatcc atgatatcaa
     2581 gatccatcaa cacatctttt gtgccttgct tcaaccggac gatatagaca ttgttctttt
     2641 ttaatttcat ttttttacga acgagtagct cacttcgtac ctgataatga tctttcaaaa
     2701 gagaatagat acgtctggca attgcagcat tttctgtttg gacgttcaaa ataaactgct
     2761 ggttcacaat acctaaagag ccgttcattc gcagcaaagc agctaattcc gctttcgcat
     2821 gttctcgatg aacttccaaa ccagttagtt ctttcttcac atctgcagca aatgacatcc
     2881 tattctcctc ctttctccaa caataaattg cttaatattt tgaaccgaaa actaaacgga
     2941 acaattcttc tactactttg tctccatcgt ggaagacacc accatctttc aattctaaaa
     3001 agtcggtgga aatcactcga catccttcat ttctcaatcc gttgaagtcg tgtgcgactt
     3061 gtactagata ctcatcatag atctctgggt ccatataatc ttcaggcact ttttccgtat
     3121 tgaccaatac tgtatcgata aaaggctgat tcaaatgctt gtgtaaaaca cgtatatgat
     3181 cggcatctgt gaaatgttcc gtttcccctt tttgggtcat gatattacag atatagacgg
     3241 tttcagcagt tgtcttgagc attgcttcgc cgatttctgg tatcactaaa tttggaagga
     3301 tactggtgaa taaacttccg ggtcccaaaa cgaccatgtc ggcgtccata attgctgaaa
     3361 cgacttttcg agccgctttg gcttcacttt tatcatttgt gttgcagaca tacacacggt
     3421 caatggtttt acggttgatc gcgattttag attctcctac tgcagtcgtt ccgtctttaa
     3481 aaacagcatg caaggtcaaa ggagtttctg aagaaggata aacatgtcca tctacatgca
     3541 tcatttttgc taataattga atcgcctcat aagtgcttcc ccgcatctcg gaaactgcgg
     3601 caatgatcag attaccgatc gtatgattgg ctaaaaactg atcttccttt ttgaaacggt
     3661 attggaaaat atcttcatag aattgtggca tatccgataa cgccactaag acatttctca
     3721 agtcaccagg aggagccata gcgatcgatt ctctgattgc accgctgctt ccaccatcat
     3781 ctgcaacagt cactactgct gtgatatctg ctccttgatt tcgtaaactt ttcaggataa
     3841 ctggcagacc agtgccaccg ccgaccacta cgatctttgg ttttcttatc cggtaggttt
     3901 tcattttcac gaccggttca ccgtctcttt ccttttatcc ttgtcccgat gtgtcacatt
     3961 gactttatag tttttcccta aagcatttgc caaacgttca gtcaatgcca cagaacggtg
     4021 ttgaccgcct gtacagccga ttgcaactgt caagctgctt tttccttctt taatgtatcc
     4081 aggcaataca gtttccagaa gatccaaaaa tttatggtag aatgattgcg tttcatcaaa
     4141 ggacatcaca taatcataga ctggctgatc ttttccggtc aatggtctta gttccgggat
     4201 ataatgaggg ttgggcaaaa aacgcacatc catcacaata tccgaatcga tcggcaaccc
     4261 gtatttaaaa ccaaatgata caaattcgat ccgaaatcct tggtctccct ttgatttgaa
     4321 tgactcattg attttttcac gtaattgtcg tggtgtcaat gttgtcgtat caatgatcac
     4381 ggaagcttgg gctttcaagt cgtctagtat cgcccgttct ttacgtatcc cttcagtgat
     4441 caaaccgtcc atcgccattg gatgtgctcg tcttgtttct ttgtagcgag ccactagttc
     4501 ttcgtctgaa gcatctaaaa ataagataga agtgtcgatg aagttcgtat tttcgatttc
     4561 gatcagcatg ttttggattt cttcaaagaa ggaacgagaa cgcaaatcca ctcctaaagc
     4621 catttttgtg actttacctg attctttgat caattcccag aattttggaa tcaatcgagg
     4681 cggcatatta tcgatacaaa aatagcccat atcttcaaaa ctttggatag ctactgtttt
     4741 ccctgcacca ctcatacctg ttatgatgac taattgcaaa ttatctgtca tatttacgaa
     4801 cccctctcac attgtgcata ataaaattat atcatcccgg gcgtatcatt accagttttc
     4861 tttttctttt acaaaaagat ttggaccaaa tatcttttag gatatttgcc ccaaatccaa
     4921 tttttttact tttccgatgc tgtatccaat gcctcgcttc tttcagctaa tgcacgttcg
     4981 atcgttcgat ccgctaaaat agattgagca tcgatcactg ggtaatgatt atcttcagca
     5041 aattcatgca tcaaagataa ttctgtgcaa cctaggatga ctttttcaca gtttaggcgc
     5101 tctaccgctt cctctaagat ttcgtaatag agctcttgat tcaaataatc cgattccttg
     5161 atctcatgat agatcaggta attgattttt tcttgaagcg cagtatcagg aatcactgtt
     5221 tcgaaaccaa gatttttgac ttcgcgttca tagattccag ctttcatact tccttctgtt
     5281 cctagaatcg ctactctccc tgtcgtatgc tgacggacaa gttcatttgc tgcttctctt
     5341 ggcatatgca agataggaat atccgttgcc gcttgtaact cttcaaaaaa gtagtgtgcg
     5401 gtgttacaag tcaacacaat gaagtttggt cgcaataaat tttgtttctc aatatcatcc
     5461 agcagaaacg gcattggatt ttcttctgat cgatctaaaa tataagctgt acgatcagga
     5521 actgttgcat gattgaataa gacataattc aaatattctt gatcttttgt agctttcgtt
     5581 cggtggttga tcaagcgaac aaaactttct gtcgccatcg tgcccattcc gcctaaaata
     5641 ctgaaaaaat tctccatgaa ctagccttct ttcacatgaa aatacttttt gaatcttgga
     5701 atatagttat ggaacatata tttcatcaac aaccagcgct tgattgatcg gtctttttca
     5761 taaaatacag tagtaccgta acgattttct ttgatcattt gctcagctag ttttttgtct
     5821 tcattttccc gagcatattc taaaaagatt tttttgggca cacccatcca taatcttgct
     5881 ttatctgatt gattcgttcc ataggtcgtt tcaacaaagg gtttgttgaa cactcgatct
     5941 tctgtgacaa aacgagccag attcaagccg ttcaatgtca caaagaaact gctacgacct
     6001 tgtctcaaat tgatttcaaa taatttatat tctccatctc taggatcata cttcatatcg
     6061 aaattggcaa agcctgtata ttcgattttt tccaaaaatg ccttaatggt ttgatagatt
     6121 ttttcgttat aatctggcat gatcacaacg taattaccaa tcgatgctgg tgtaggatct
     6181 tctaatagtg gatgaccaag gcacatcatc cgaacttgat gatcttcatc tacatacgca
     6241 tttagcacac gcatattact atcatcaccc gggataaaat cttgtacaat catttcactt
     6301 ttataaccgg cttcgtatat ccggcctaaa attaaatcga actcttctct agtctctaaa
     6361 ataaaagctt tttttcttcc ttcaaattgg acagaaagat actccacact gtttgcaggt
     6421 ttcaaagcaa ctgggaattc aaaaggcaat tcctgttcca aatgtccatt tactaacatt
     6481 tcttctctga cgatcaatgt tttaggatac ggaagatcat attcttcaca aacttcataa
     6541 aagcttactt tattgatcag cctttcaaat aaagaataat caatatatgg acagataaaa
     6601 tattctgaca gctcttgttt atgttgggag atcaattctg catatccatc accacaagca
     6661 atcaaaagat attttttact cttatcagaa tatctttctt ttgccaaacg aagcatcgtc
     6721 tcgataaata cagggtcttt atcaaatcct ggaataactt ctacattgac aattttactg
     6781 tagcgggtag gggctaactg atccgaagca tatgcttggc agattttgcc gtatgcttca
     6841 ttaaaagaac gtgccatacc ataaacgttc atgtcgcttc ctaataatat agggataaat
     6901 tcttcatttt caatactgtt catcattatc tctcacttac tcataatctc ttgtttttct
     6961 tttccaacta cacaaggaat atcataccat aaagaaaaaa gcaatcaaag gaaagtcctc
     7021 cgattgctca attctttttt gaacggattg aacttatagg aagtttttat ctataccaat
     7081 cagtgtagaa agaactacca tgtaatgatt ctagaacact gatattaata aaacaagcaa
     7141 aaattcattt ttttatgttt ttttaactat ctcagctatc tatcctcttt ataccattat
     7201 ttttttcaaa tagtgacctg tataactttc ttttacgtta atgatttctt ctggtgttcc
     7261 agtcgcaagg atcgttcctc caccttctcc accttctggt cctaaatcaa tgatataatc
     7321 tgctgttttg attacatcta gattgtgttc aatcactaaa actgtgttac cagcatctac
     7381 taatctttgt aatacatgca acaagcgggc gatgtcatcg ctatgaagtc ctgtcgttgg
     7441 ttcatctagt atatagaaat tctttccatt agagattttg tgcaattcac tggcaagttt
     7501 catccgttgt gcctcaccac cggacaatgt cgttgctggt tgccccatcg tcacataacc
     7561 taagccaaca tcaacaatcg tttgcagttt gcgatgaatc tttggaatgt gcttgaagaa
     7621 ttctacagca tcctctactg tcatttccaa aatatcagca atgctttttc ctttgtaatg
     7681 cacttctaat gtttcagaat tatatcgttt accatgacat acttcacaag gaacatagac
     7741 atcaggcaaa aagtgcattt cgatcttaat aattccatcc ccgcgacaag cttcacaacg
     7801 accgcctttt acgttgaaac taaaacgccc tttcttataa ccccgcattt ttgcctcgtt
     7861 cgtttgagca aataacccac ggatatcatc aaatacactt gtataagtcg ctggattact
     7921 tctcggcgtc cggccgattg ggctttgatc gatatcgatg atcttttcga tactttcgta
     7981 gccggaaatt gtcttgaatt tacctggctt agcagaattc ttatttaatt tttgcgctaa
     8041 cgatttcttt aagatactat tgaccaatgt actctttcca gaaccagaca cacctgtgac
     8101 tgctacaaat tctcctaatg gaaattcaac actaatattt ttcagattgt tttctgaagc
     8161 accagtgatc ttgattgctt tcccattacc tttacggcgt tcttttggta cagggattga
     8221 ttttttccct gaaagatatt tccctgtcaa agaattttca tcattagcta cttcttcagg
     8281 agtgcctgca gccacgattt gtccgccttg ttctccggcc ccaggtccga cgtcaatcaa
     8341 ataatctgct gcccacatcg tatcttcatc atgttcgact acaacgaggg tgttgccaag
     8401 atcacgcatt ttctttaatg agccaatcag tcgatcgttg tcgcgttgat gcaatccgat
     8461 cgatggttca tctaaaatat acaaaactcc agaaagattc gatccaattt gtgtagccaa
     8521 tctgattcgc tgcgcttctc ccccagataa tgttccggaa gcgcgactca aagttagata
     8581 gtctagtccc acattttcca agaatgaaag tctgtcattt acttctttta aaatcggttt
     8641 ggcaattact ttctcttgtt cagataacgt taagtttgag aagaaatcta ctgctttttg
     8701 aatagacaac tcatttgttt gcccgatatt cgttccattg atttgaacag atagagcttg
     8761 gggattcaat cgataacctt tacatgtctg acaagttaat tctgtcatat aaagacgcat
     8821 ttgctcacgc gtgaaatcac tgttcgtatc atgataacga cgctcgatat tcttcaatac
     8881 cccttcgaaa gtcgtttcta catcgcgaac gccaccaaaa tcattttcat aatggaaatg
     8941 gaaaagatca tctgtcccat tcaagatgat ctcctgatgc tcttccggta attcttcgaa
     9001 tggtgtatct aaatcgatac cgaaactttc acaagcctgc gctaacattt gaggataata
     9061 ctgagagctg attggattcc atggaacgat agcaccttga ctaagtgtct tcgttctatc
     9121 tggaatcact aaatcttgat cgacttctaa tttgacacct aaaccatcac agtctggaca
     9181 agctccaaaa ggcgcattga atgagaacag tcttggttct agttcgccaa cagtaaatcc
     9241 gcaataagga caggcatagt gttcgctaaa caacatttct tcttcaccga tcacgtcaac
     9301 cagagcatag ccgtctgcta atcgcagggc cgcctctaaa gaatcaaata ggcgagaacg
     9361 aatcccttct ttcacaatga tccggtcgat gacgatcgcg atatcatgtt ttttgttttt
     9421 ctccagctca ggcacttcac ttaaatcata gatctcacca tcgactcgaa cgcggacgta
     9481 tccctctttt tggattcgtt cgaatatttt tttatgttgt ccttttttct ttaccacgat
     9541 cggtgccaac acttggatct ttgtgcgctc aggcaaagcc attacttgat ctgccatttg
     9601 atctactgat tgactggtaa tctcgatatg atcgttggga caaatcggat gtcctacacg
     9661 tgcaaacaac aagcgtaaat agtcattgat ttccgtcaca gtacctactg tcgaccgagg
     9721 atttttactt gttgttttct gatcaataga aatcgccgga ctcaatccgt cgatgctatc
     9781 tacgtccggc ttatccattt gtcctaaaaa ctgacgagca taagcagaaa ggctctctac
     9841 gtatctccgc tgcccttcag cgtacagcgt atcaaatgct agggaacttt ttccagaacc
     9901 ggacaaacct gtaacgacca cgaatttatc tcgtggaatc gttacatcta tatttttcaa
     9961 gttatgggca cgtgcaccat gaatcgtaat tttatcgtta gccatgttgt cctcctactt
    10021 tgaagctttt aattctaaaa tcatatctcg cacattcgcg gctgtttcaa aatccaaagc
    10081 ttttgccgca tctttcattt ctttttctaa tttcatcaat aacgtgtctt tttcttcctt
    10141 cgtcatttct tcgtacgaga cttgtaccgc ttcttttgta tcatcttccg attctttcgt
    10201 aatagaaatc aaatctcgga tttctttaat gatcgttttt ggaacgatcc catgttcttc
    10261 attgtacttc tgctgaatcg tacgacgtct tgacgtttca tccatcgcta gacgcataga
    10321 atctgttact ttgtctgcgt acatgattac tttaccttct tcattccgag cagctcgtcc
    10381 aatcgtttgg actaaggaac gttcactacg taaaaagcct tctttatccg catccaagat
    10441 agcaacaagg gaaacttcag gtacgtctaa tccttcacga agcaaattga ttccaactaa
    10501 cacatcaaat tcacctaatc gaagatctcg aatgatttct gttcgttcca gcgttttgat
    10561 atcactatgc aaatatttga ctttgatccc taattctttg aaataatctg tgaggtcttc
    10621 tgccattttt ttcgtcaatg tcgttacaaa cacccgctgg tctttttcga ctcgttcatt
    10681 tatttcgcct actagatcat cgatttgtcc catgattgga cgaacttcga tcactgggtc
    10741 aagcagccct gtcggacgga tgatttgttg gataacggta tctgtttgtt catgttcata
    10801 tggtcctggc gtcgcagaga cataaatgat ctgattgaca tgtttttcaa actcttctaa
    10861 ccgaagtggc cgattgtcta aagcagatgg caaacggaaa ccgtaatcta ctagcatctg
    10921 ttttctcgct cggtcaccat tatacattcc tctgatttga ggcatggtta cgtgcgattc
    10981 gtccgccacg atcaaaaaat cttcaggaaa gaaatccaat agcgtataag gcggttcacc
    11041 ttctttacgt ccgtccatat gccgagaata attttcaatt cccgacgtgt agcccatttc
    11101 taacatcatt tcaatatcgt aattggttcg ctgttctaaa cgttgagctt ccagaagttt
    11161 gttttcattt cgcaagacag ttaaacgctg ttctaattcc tctttgatat tcgctacggc
    11221 atgctccata tgttcatcat tcgtcacaaa gtgagtcgcc gggaagattg ctacgtgttc
    11281 cgtttctcct aaaacttcac ctgtcagtgc attgacttct cggatacgtt cgacctcatc
    11341 tccaaaaaac tccacacgta aggcacgttc atctcttgaa gccggaaaaa tctccacgac
    11401 atcaccgcgc actcgaaaac gaccgcgctg aaaatctata tcatttcttt cgaattggat
    11461 actgactaag tcacgaatca actgattgcg atctagttct gctccctgtc gaatcgaaac
    11521 tacttgtttt tggtactcaa aaggcgagcc taatccaaaa atacatgaaa cggatgcaat
    11581 gacgatcaca tcatttcttt ctaataatga actagtagcc gaatgtcgta atttgtcgat
    11641 ctcatcattt acacttgaat ctttttcgat atacgtatcg cttgaaggca cataagcttc
    11701 aggctgataa taatcataat aagaaacaaa atattcaaca gcattgttag ggaaaaattc
    11761 cttgaattcc ccgtacagct gaccagccaa tgttttgtta tgggcaataa tcagtgttgg
    11821 tttattcact ttctcaataa gattggaaat cgtatatgtt ttccctgttc cagtcgcacc
    11881 taataagatt tgtgcttttt tcccgccgac tacgccatcc actaattggt taatcgcttc
    11941 aggctgatca ccagccggtt ggtatttcga gacaagctca aagtgtcggg aggtatctct
    12001 ctcaatcatt cttcgtcctc cttttcattc attccttttc attttacgac caataaaaag
    12061 aaaaggaaag caaaggcatt ccttactaaa aaattatacc acaccgaaca tactttcgcc
    12121 acttttttat cttattatac atgttatgtt ttataacata aaatgttaga aactcgcatt
    12181 tttttcattt tttcgagctt acagtcttgt ctgattcagc acttttcgcc tataataata
    12241 aaatattgga aatttaggag gttgattatg aaaagaaagc atttatttca ctcatttgtt
    12301 ttcttaatga caggacttgt gacacttgcg tttggtcatg ttgcacaagc tgacaacact
    12361 acaacggcag agtcaagcac aagcgagaca atgcaaaaaa tagagcccaa aaaagacgta
    12421 tacgtaattg ccagtgactc tgcttttgct ccatttgaat ttcaaaacgc aaagggcgag
    12481 tacgaaggca tcgatgtaaa attgatggaa aacatcgcca aactgcaagg atttaacatc
    12541 cgaatggact accgtggttt ctctgctgct ttgcaagctt tggaatcagg acaagcagac
    12601 ggaatgattg ccggaatgac tgtaacagat gaacgaaaga aaagctatga tttttctgat
    12661 tcttactttg atagcgggat ccaattagct gtcaaaaaag gagatacttc gatcaagtct
    12721 tatgaagatt tgaaaggaaa aacagtcgga gcaaaagttg gtaccgaaag tgctgaattt
    12781 ttaagcgacc atgaatctga atatggctat tctatcaaat attttgatgc tgctgatcaa
    12841 ttgtacgacg ggttaaaagt tggcgcaatc gatgcaatga tggatgatta tccggtaatc
    12901 ggttatgcga tcaaacaagg acaagaattg gaaacaccga tcaaaaaaga atctggcgga
    12961 aaatatgcat ttgccgttaa aaaaggacaa aatcctgagc ttcttaatat gttcaatgaa
    13021 ggattgaaag aattaaaaag aacaggcgaa tacgataaga ttattaaaga atatgtagcg
    13081 gatggttcag aaacttccag tgagtcttcc actgctgatg aatcaacatt tcttggactt
    13141 atccaaaaca actatcaagc attgttgaaa ggactttgga gaacaattct cctaactttg
    13201 atctcctttg ctttggctat agtaatcggt gtgatttttg gattattcag tgtagcacca
    13261 atacgcgctc ttcgcacaat tgctagtatt tatgtcgata tcatccgagg aattccaatg
    13321 atggttcttg cgttctttat tttctttggg ttgcctggta tcgttggatt tacgattcct
    13381 gacttccttg ctggtgttat caccttgact cttaacgcaa gtgcttatat cgcagagatt
    13441 gttcgaggcg ggatcaacgc cgttcctgtc ggacaaatgg aagcttccag aagtttaggt
    13501 ctttcttata atcggacaat gcaaaaaatc attttgccgc aagcgatacg catcatgatc
    13561 ccatcattcg tcaatcagtt cgttatctca ttaaaagaca caacgatcat ttccgcaatc
    13621 ggtgtagtcg aattgctgca aactggtaag atcattgttg cacgtacaac acaaagtacg
    13681 tatgtttact tgatcattgc gatcatgtac ttgattttga tcacagcatt gacaaaatta
    13741 gcaaaagttt tagaaaagaa ggtgaagtaa gatggcagaa aaaatcttag ttgagcattt
    13801 agtcaaaaaa tacggcgata acacagtatt aaacgacatc aatgtatcca tcaacgaagg
    13861 agatgtcgtc tgtatcattg gcccttcagg ttcaggaaaa agtacattct tgcgttgctt
    13921 gaatcgttta gaagaacctt ctgacggtga aattattatt gacggcgccc acttgatgga
    13981 taaaagcaca gatatcaact tggtgagaca acatatcgga atggtattcc aacactttaa
    14041 cctattccct catctttcta ttttggaaaa catcatttta gcaccgatgg acctgaagaa
    14101 agaatctaga gaagaagcag agaaaaaagc aatcaaatta ctgcagacag ttggtctaga
    14161 agataaaaaa gatatgtatc ctgaaatgct ttctggtgga caaaaacagc gtgtggctat
    14221 tgctcgtgct ctagcgatga accctgacat catgcttttt gatgagccta cttctgcact
    14281 cgatcctgaa atggtcggtg atgtcttgaa cgtcatgaaa aagttagcag aacaaggtat
    14341 gacgatggtt atcgttacgc acgaaatggg gttcgctaaa gaagtggcca atcgcgtcat
    14401 gttcattgac gacggaaact ttttagaaga tggaacgcct caacaaatct ttgaaaatcc
    14461 gcaaaatgaa cggacaaaag atttcttgaa taaagtatta aatatttaaa ataaattata
    14521 tatgtctttt tgactatctt tttatatctt cttaaatgtc cgcaaagcct tattttatag
    14581 gctctacggg cattttgctt ttgtggtaaa cctcacatat ctaggtctat cttcttatat
    14641 tttcactatc aagcgtggtt aaaatcgtgg taaatacttc tatgcaatta gacgctgaac
    14701 ctctgatttt gcggtatcta tggacgcatg agcataccag ttcattgtga tactgatatt
    14761 tgaatgcccc atgatatact gtaaatcttt tgggttcatg ttcttgtttg ccagtcttgt
    14821 gcagaatgta tggcgtagcg tatgcggtgt gatatgtggc aatggattgt ccttgtggtg
    14881 cttgttgtat ttctttacca tacggataaa taaggcgtta taatcaatcg caactttggg
    14941 cttgccctta tgattgacaa ataggaagtt gccccgtccg tctatcacaa atggttctgc
    15001 ctttggacgt tttttcataa cctgttgaaa tgcctgtatc gtttctttgc ttaatggtac
    15061 ttgccttatt ccgctttttg ttttaggcgt ttcaatataa tagccctgtt ccttgctctt
    15121 tagtaactgg tggtcgataa tcacaacttc attcttgaaa tcaatgtcgg ctactgtcag
    15181 tccgcacagt tccgaaatac gaagtcctgt ctttaacagt atcagcacat catcataatg
    15241 cttgtgatac acattgtccg tcttgatgaa tgagagtaag gcttgttcct gttcctctgt
    15301 caatgcgact ttctttttgg tatcattttc taggacttca ctcaacttga aatcaaaggg
    15361 atttttcctc acataatcat cttgaatggc tatgtagaat gacgctttta acgagcgttt
    15421 atggttgtta atggtattgt aggaaaagcc tttgtctttc atgcgtaacg cccattcctt
    15481 agcgtcagag ggtttgattg tatcaatgct cctagcacct aacttgtcct ctttcaataa
    15541 ccgcatgagt tgttcccgtt gtttctgtgt gcttttcttc acatttgccc tctgtgcgtt
    15601 ctgtttggca taaagttggc aaagcgtcat tttcttgcca gtgctgtcga taccgtcctc
    15661 aatatcccgt cttatctgct gttccagttc tcgaagtgag ggtttttccc gttttccctt
    15721 tggtgtcggg tctgtgggtg tcaatctcca agcatacaca tattttgtgt ttccaaatgc
    15781 gtctacatat ttatataagt attttctgtc tgttcgttgg ctctctccag tatgcaggat
    15841 acgacctttg ttatcccgtc ttttttcttt catggtgtct gctcctttcc ttgttggaaa
    15901 gagccttgat atgacttgtg ttcatcataa cacatacaag gctcatttgc attagatagc
    15961 gtccaattta tcaatgacct gttcaaactg tcggcgttta atctgtatgc ggttgccatt
    16021 cataatgagc cagccagcgt ccttgttttc ctctgccaat cgtcttaact tgttttctcc
    16081 gatacggaaa tactttgacg cttcttcaat ggtaagggtg tatttttccc atacgggaat
    16141 atcctgtgca ttactcataa aacaccccct cactttcgat tacgtctgct atgtccgtac
    16201 acatctgttc cacaagcatt tcctgctttt cagagaggtg ggtacattca tcaatcattt
    16261 tcatgtagtt tgagcctgtc agcctgtcga tttcctctat catcacgatt gacggcatga
    16321 cctgtctttc cagccattgc agagtgcgtt ccatattgac aggtacgggg ttcatttcaa
    16381 aaggtaaact gtcatgggaa atgaatatct cccacagcgg atagtcggga aattgcacaa
    16441 aatcagtaat aaggtaaaac accagcccat gagggttata tgtcaataac aattcctcaa
    16501 ctgcctgtac tgcttttgta ccacgcagac gaatttcaaa acgattgata atatccgtat
    16561 gtttcttttt ggttgcctgt tccttttgtt tttcatacag gcagaagtat tttgtgcttg
    16621 cctttgaacc gatataaagg gtgcttgcta aattacggtt ttttccgctt agttttccac
    16681 cctgcacatt ttcataattt ttacagcgac aatccgcacc gccatttctg tatttttcag
    16741 acaaaacggg aatatccaac agaccacaca tatcattgat tgccaagtca aaacgtcgga
    16801 taacaccgtc acagtcaaga cagcggttta aaaatgaata ccaatctctg ttctgtgcct
    16861 gcaagacata ttccatgttg cgtgagcctg ccccttttaa ttccaagaat acgcccatgt
    16921 gttcgtcatc agaagccatg accttgattt ctccgtaggc gtaatgctct ttatagccat
    16981 aatacccata gtcataatgg ataaaataat ctgctttcat gccaagcacc tttcggataa
    17041 tttccaatgc gtcagtcgtt ggataacgga cagacagata atcaacgagc agataaaaag
    17101 gcttatcgca gatataataa ttcagacaac gcaggataat attttgtgtt tccttgctgg
    17161 cgttggcttt tccgttctca aagcggttga tactatatct tgatacatgg gtaagacttg
    17221 caagttctcc ttgtgaaaga ccgcttgcaa gacgtttgtt cttcatttca agtgcaaatt
    17281 ctaaattgtt cattgtattc ctccaatccc acaatagcct tgaaatacct gtaaacctct
    17341 attcaaaaag tgtgatatgc actatcttct taaaacttct cattactact cacaactttg
    17401 ggattgtatg gtttttgact tgtcttttgt gaaatagtgc ccccctgtta gataacgggg
    17461 gcacagacaa ggctcgcagg ctcgccagcc gacaaagcat ttcttcccct tgacacaagg
    17521 tgtcatggcg gtaagcctga gaggcttccg ccaccgtgtc agaaatactt tgtcagcaag
    17581 ttctgttttg ccttttctaa caagttccat ttcaaccgat attcatatct acggatttaa
    17641 tcagataggt atttcttttt gaatgttttt atatttcatt ctattgtgct tattcgatta
    17701 caagaacata gtaattctta tatgcttatt tgtcaatatc tttttttgcc tttacaaatc
    17761 atattaagca tgatagactt ataatagcga agatataacg agatatggag ggttatgcaa
    17821 tgaaaataag ccatttagga aataatatac agaccataag aaaatttagg ggaatgaaac
    17881 aacaggaact tgcggacaaa atcggtatca atatgcagag cctttccaag attgaaagag
    17941 ggttgaacta tcctgcctat gaaacgctgg aaaagataat ggaagtgctg gacgttacgc
    18001 ccaatgaatt gttgtcggga gaatggaagt atgtcaatca atctgaaaag gaagtctgtc
    18061 agtttttaag agccgaagaa cgtctaaatg cagaactgaa acatggacac tatgataact
    18121 tctttgacag cgaggaagaa tggctggaat atgagttaga aaagttacgg gaatatatta
    18181 cagactatat caacgggaaa agcattgaag cgtccgacct ttacccaatc aaagaattta
    18241 tccagcattt gaagtttcaa aaattattag accgctatga tgatttatac agtatggata
    18301 tgtttgggga aagcatagag ggacataagt ataagacacc ttatcaagtc gtgaaaatga
    18361 taaacccgaa ctcaaaagaa gatatggaac tgttacgaga agtattaagg aataacaatt
    18421 ttgatgatga ggacgagtaa cttttttcct cttgcgagaa gatacagcaa acaaaaagcc
    18481 cgatcaagag tgcaaagcac caccaatggt ggcaaagctc ttgacagggc tttttctttt
    18541 ctgttgtggg caatcaagag gaagaaaggg ataaaatctg atttgtggta aatcaggcaa
    18601 aggcaacgca ggtatctcaa tttgatttgg tacttgaaaa gaacgggagt aattggaaga
    18661 ttatagaata acaaatattg gtacattatt acagctattt tgtaatcacg tactctcttt
    18721 gataaaaaat tggagattcc tttacaaata tgctcttacg tgctattatt taagtatcta
    18781 tttaaaagga gttaataaat atgcggcaag gtattcttaa ataaactgtc aatttgatag
    18841 tgggaacaaa taattggatg tcctttttta ggagggctta gttttttgta cccagtttaa
    18901 gaataccttt atcatgtgat tctaaagtat ccggagaata tctgtatgct ttgtat
//
LOCUS       DAPBAF010000051        18104 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.051, whole genome shotgun sequence.
ACCESSION   DAPBAF010000051 DAPBAF010000000
VERSION     DAPBAF010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 18104)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18104)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18104
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.051"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(14..961)
                     /locus_tag="RD451_002266"
     CDS             complement(14..961)
                     /locus_tag="RD451_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HDT7567494.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
     gene            complement(1139..1942)
                     /locus_tag="RD451_002267"
     CDS             complement(1139..1942)
                     /locus_tag="RD451_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HDT7567495.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            2088..3002
                     /locus_tag="RD451_002268"
     CDS             2088..3002
                     /locus_tag="RD451_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HDT7567496.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKDVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            3050..3520
                     /locus_tag="RD451_002269"
     CDS             3050..3520
                     /locus_tag="RD451_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HDT7567497.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            3605..4213
                     /locus_tag="RD451_002270"
     CDS             3605..4213
                     /locus_tag="RD451_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HDT7567498.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNSAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            4347..4547
                     /locus_tag="RD451_002271"
     CDS             4347..4547
                     /locus_tag="RD451_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDT7567499.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
     gene            5301..6527
                     /locus_tag="RD451_002272"
     CDS             5301..6527
                     /locus_tag="RD451_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HDT7567500.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
     gene            complement(6635..7105)
                     /locus_tag="RD451_002273"
     CDS             complement(6635..7105)
                     /locus_tag="RD451_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HDT7567501.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGKYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
     gene            7427..8005
                     /locus_tag="RD451_002274"
     CDS             7427..8005
                     /locus_tag="RD451_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="HDT7567502.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            complement(8179..9560)
                     /gene="rlmD"
                     /locus_tag="RD451_002275"
                     /pseudo
     CDS             complement(8179..9560)
                     /gene="rlmD"
                     /locus_tag="RD451_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
     gene            9667..10464
                     /gene="recX"
                     /locus_tag="RD451_002276"
     CDS             9667..10464
                     /gene="recX"
                     /locus_tag="RD451_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HDT7567503.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            10457..11635
                     /gene="mutY"
                     /locus_tag="RD451_002277"
     CDS             10457..11635
                     /gene="mutY"
                     /locus_tag="RD451_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HDT7567504.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            11729..12262
                     /locus_tag="RD451_002278"
     CDS             11729..12262
                     /locus_tag="RD451_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HDT7567505.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(12340..12774)
                     /locus_tag="RD451_002279"
     CDS             complement(12340..12774)
                     /locus_tag="RD451_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7567506.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
     gene            12916..14034
                     /locus_tag="RD451_002280"
     CDS             12916..14034
                     /locus_tag="RD451_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDT7567507.1"
                     /translation="MFEKLRQSKLMFWSLELLIIAALIMISSEINFIFEPIGTFFSTL
                     FAPVLIAGFLYYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQI
                     SSLASNMPDFIKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSL
                     GSIVGTIASATVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTL
                     ANYISGQAIECLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLV
                     TVFNDPVKALLCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLG
                     IFLGVPFYAICKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            14162..15538
                     /locus_tag="RD451_002281"
     CDS             14162..15538
                     /locus_tag="RD451_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HDT7567508.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            15939..17519
                     /locus_tag="RD451_002282"
     CDS             15939..17519
                     /locus_tag="RD451_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HDT7567509.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            17717..17941
                     /locus_tag="RD451_002283"
     CDS             17717..17941
                     /locus_tag="RD451_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HDT7567510.1"
                     /translation="METEWQRRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
BASE COUNT         6073 a         2965 c         3631 g         5435 t
ORIGIN      
        1 ttgttttcag ctattaatat cctgcagaca attttacttg attggtttga agctcatggg
       61 tggcaaagta gcttttcaga ttggttaaaa aaatagccat taatttcttt tgaaaatcag
      121 gtgtcaaacc tgcaatgtgg gaagtaatca gtacattgtc cattttccaa agaggatgat
      181 cttgtggaag aggctcttcc tcaaaaacgt ctaatgctgc aaaggaaagt tgctggttat
      241 ttaaagcctg caccagatct tgtgtcttaa cagaagcacc acggccaaca ttgatgaata
      301 cagattttgg atcaaagtgt tcaaacatat gctgatcaaa gagcccagtt gtttcctccg
      361 ttagaggtaa gatattgact acgaaatcta cttcaggaag aacttccttt agttgattta
      421 aagaaaaagt cttttccatt ccttctgctg gatgaccgga tgtattgatt ccatagcagt
      481 tcatgtctaa tgctttgcat ttttttgcaa tcatttttcc aatatggcca gttccaatga
      541 ttagtatttt tttcccttgg atagattggt aatggaccga tgaacctaac catttcatgt
      601 cactctgtgc cttttgtgct tgaaaaagac cacgagaata cccaaggatg attcctaaga
      661 catgctccgt aatcgattca ctgtggatgc cactaccatt tgaaagtaaa atatgtttct
      721 ttgaaaaagt ctcaaggggt agctgatcaa caccagctga gatagattgg acccatttca
      781 aggtagaaga ggctaatagt ttttcttggt agtctgagtt ccagcccaaa ctgatctcta
      841 cattttgtag atcctctggt tgtaattctg ttttaaagat ataaccaggc gctatagtat
      901 ggatttcttc gataaattca tcacgaaatg gacgatctgc ataaatgatt ctttctgaca
      961 tagttaattt cccgcctttc tttactctaa gtgtagcgca tacaagaaga actttgaagc
     1021 gccttgcttg ttttttgaga aagaaatatt tttcaaataa aaaaggggct gtgacaaaaa
     1081 aatgtcacaa cctctaaaag ggtctattga agtagaaata acgagttgtc tttatttctt
     1141 aattgatcga tatttttgcc catcctttga cagcttgagc aaaaataaag attcctgcaa
     1201 aagcaatgaa ggcgctagtg tcaaaagaag gaagaaagac catcaagatt gttgcaatta
     1261 tagtaggcaa tgaaattgaa tagatcaatg tttttaaaca atcaagaaaa gtagcttttg
     1321 ttagtcgaaa gcgtgcatag agaaaagcag caatgttggt aaatagcaaa gtgatcagca
     1381 gattcagaaa actaggataa atagaaaata taaatgtcag gacttttatc caaagtggta
     1441 tagatgcttc acttaaaaaa gaacggagct gcttacctgt taagtttttt aaagattcat
     1501 tggtgtaggg aagttctaat tggttattgt tcaacaaagc agaagtcgtg cctgtattag
     1561 gaagagctat gataagtttg ttttttaaca tcccgacact aacaaaattc cccatcaaat
     1621 cagtagagat gtcctgttct gttcgttttc cctctggatc aaatgtgaag ataatggagt
     1681 ttgtttggta aatgaatcct tctttttctt cggtttgaag ctgcccgttt tggattgtaa
     1741 aatcaggaat gcgagtagca atcttttgcc catccaattg aatgttgttt aagacttgaa
     1801 aaacttgaaa agagattggc aaagccataa ttatactcaa aactaaaaga tagacaatgg
     1861 ctttccaaaa tgggacattt ctcgcctcct ttaggtcttt gaatcgtata aaggaactga
     1921 taattaattg ttttgttgtc ataagtactc ctcatctagt agtgtcatca cttgcaattc
     1981 tagcgaagta tcaagtgaaa tacaagtgct ttaaggaaac agctgaatga ttggtgaaat
     2041 atcaaaaaaa tgttattctt gtctaaagac tatccaatat aaataaaatg gaggaaggaa
     2101 tagtgcctac acagccacag agatcatcaa aaaaactatt tggagtagtg gttttgaatg
     2161 cggtgatcac tttatcagaa tttattggag ggattatgtc agggagtttg tctcttgttt
     2221 cagatgcttt ccataacctt agtgatacat tggcaattat tttttcttac ggggcacaaa
     2281 aaatggcccg aaaagaagca aataaaaaac gtacgtatgg ctaccagcgt ttagaaatat
     2341 tgagtgcttt catcaactca ttcatattga tcatattatc cttgttttta accgttgaag
     2401 cattcaagcg gttcacttca ccagaaaaga taaatagtca tttgatgcta acagtagcag
     2461 ttattggatt gctcgcgaat ttgttctcag tattattatt acgacaagaa gcagatgaaa
     2521 gtttgaatat aaaatctagt tatttgcatt tgttaagtga tacactgtct tcggtaagtg
     2581 tgattatcgg agcaattttg atccgttttt tcgatatcta ctggatcgat ccagttatta
     2641 cactgatcat ttcgatatat atattgatag aagcgataat ggtgatcaaa aaagctgccg
     2701 ctattttgat acaaagtgca cctgctatcg actatgaaaa aatggaacaa gaaattgaag
     2761 caatcgatgg ggtaaaggat gttcatcatg tccatatttg gcagtatagc gaaaagataa
     2821 ttattttcga cggacatatt gattttgaag atcagctact aagcgagatt gaaaagatat
     2881 atcctcgtat aatttcttta ttaaaattaa aatatggtat tacacatgtg acgatccaag
     2941 cagagacaaa ggcaaaggat caaaaaaaat taattttttt aaataaagat gaaagttatt
     3001 gaaatataga gtatgataaa taagaatttt taataaggta ggttggctca tgaagcagta
     3061 tcgacagtta aaaggatatt tagaagcaaa aggatattgg gagatactag tctatctctt
     3121 ttttggtggt ttggctacga ttgtaaattt tgttagtttt gctctcgcac gccaatattt
     3181 tgatttaagt atggccttat ccaattctat ttcgtggttt tgttctgtat tgtttgcttt
     3241 tgtaacgaac aaactttggg tattccattc aaaatcaccg aattttacac atgcacttat
     3301 tgaatgcggt aagttcttct tctaccgtat cctttcttac ggattggaca tgggggcaat
     3361 ggtattgttg atcaatgtta tgaacagcaa tgagtatgtg gcgaaaatca tcactcaaat
     3421 tattgttatc cttgcgaact atattttcag caagttgttt atttttaaag aaactgaggt
     3481 ttttgaagaa gaagtaggtc aaagtgaaaa agacgactag gcataacaat tgaagaattt
     3541 ccttctcttt gttactcttt gtaatgtaga cattattaag aaaacattga ggaggaattt
     3601 ttttatgact tacacattac cagatctacc ttatgcatat gacgcattgg aaccttatat
     3661 tgacgaagaa acgatgcatc tgcatcatga taagcatcac aatacttatg tgacgaattt
     3721 aaattcagca attgagaaat acccagaatt aggcgaaaaa acaatagaag aattattatc
     3781 tgatatggac gctattccaa cagatatcaa gacagctgta cgtaacaatg gtggcggaca
     3841 tgctaaccat tcatttttct gggaaatcat ggcaccaaat gctggtggcg aacctacagg
     3901 agaaataaaa gaagcgatta atgaagcttt tggtgatttt tcttctttta aagaagaatt
     3961 caaaaaagca gccgctggac gatttggttc tggatgggct tggcttgtaa tggaaaatgg
     4021 aaaattagct attacctcta ctgcaaatca agattctcca ttgatggaag gaaagacacc
     4081 aattctaggt ttggacgttt gggaacatgc ttattatttg aaatataaaa atgtccgacc
     4141 agattatatt gcagcattct ggaatgttat taattgggat gaagtaaaca aacgtttcga
     4201 agcagcaaaa taaccatttc ctccgtcata tcagtcttaa aaataatttg gaaaataaaa
     4261 gagcgaaagc ttgctagcgt tttctaaatt gggtataatg ttcttgcaag gttacttgca
     4321 agaacttttt tggaggatat acatttatgg aacacggaac ggttaaatgg ttcaacaatg
     4381 aaaaaggatt tgggtttatt acagtagacg gcggagatga cgtatttgtt catttctcag
     4441 caattcaagg agacggcttc aagagcctag aagaaggtca agaagtagaa ttcacgattg
     4501 ttgaaggtgc acgcggacct caagctgctg aagtgactaa attataataa tttgttgaat
     4561 aaagacacga cttcttagag agtcgtgtct ttttgtctat ttatgaagtt tttagatttt
     4621 ttggctaagt aaatgcattt gttcacttga catgtcctaa ctaattatca agcaaggaac
     4681 attttcttcg ttagtaatgg attttaaaga aatttcagtt tttggatgtt gaataaaaga
     4741 ccatttgtga aaccactagt atacatactc attaccatgt caattctatt actttaaaag
     4801 aaaatcgttt tactttgaag aggagcatat ctatccatta aaagatgatg gtaatgcaat
     4861 cactagttcg agtcatttta agagccatgc agtgagctgg aaataaaacg aatagaagat
     4921 gggtttaaca aaaggaccag tcataggaag aaattgtcgt gaaatcgaat gataatctga
     4981 acggtaggca aagactgtta aaaagatggg aaaggtatgt gcgatcattt tactgcacga
     5041 ttatttggaa aataccttgt tgttcgcttt ttctggaaaa aatacataaa aaaagataaa
     5101 acgattgcga actgcgtgta ttcggtcttt cgatcttttt cacggtatgg tatgatagtt
     5161 aagaattttg agaaatttta aaaaataata atcgttacac aaaaatgttt tttaaagttt
     5221 tcttatgatt aaaaagtgaa tttgctgatt gaacagttat atgagacaat attttagaaa
     5281 atgtgaaaca gaggtgtatt atgaagcgat ggcaaaaagt tctattaacc ttgttagggg
     5341 tattcgtttt gctgattgcc ggattatcag catacggaat cagatttatg ggagaagcga
     5401 gccaaacagt aaacaaaatt tctaaaaact ctaatcgaat atcctccaaa cgttctgaga
     5461 gagtaagcat tgatgacaaa gaaccttttt cggttttgct attaggttta gataccggtg
     5521 gattaggaag aacggaacaa ggacgttctg atacgatgat ggtagtaaca gttaatccga
     5581 aacaaaaaaa atcaacgatc atcagtttgg accgagatat ttatacgaat atcgtaggtt
     5641 atggaacggt agataaatta aatcatgcct acgcatttgg tggtgtcgaa atggccatgg
     5701 attcaattga gcaactgctc gatattccta ttgatcatta tgtaacgatc aatttggatg
     5761 gcatggaaga tttgatcaat gcggtcggtg gcatcaaagt gaataataaa attgacttta
     5821 ctttggatgg tgtccatgta ccagtaggtg aacaaacatt gaatggagaa aaaggtttag
     5881 cctattctcg aatgcgacac gaagatccag aaggcgatat cggtcgacaa cgtcgtcagc
     5941 gggaagtagt gacgaaaatc gtcaataaag ttttaagttt agatggcgta agcaattata
     6001 gaaaaatttt aaaagcagtt gagaacaatg tgacgacgga cttagattgg gatgacatgc
     6061 ttgatgtagc gacgaactac accccggcgt ttgaaacaat caaacaagac cagttgcaag
     6121 gcgaaggaca aatgatcaat gatatctact atcaaatttt aggaaaaaat gatcttcttt
     6181 cgatccaaaa tgaactgaag aaacaattaa atataaaaac aagcgataca ttacctaatt
     6241 tgaaaaatga gaatgcttca atgatgttct ttgatgattc ggaagatggc gattcgacaa
     6301 acggtgatgg atcgaatagt gaagggtaca ccgattattc ttcctattca gaaaacacat
     6361 atgatcagta ccaagatccg aatacctatt atcagcaaac agaagataca agtcagtact
     6421 atacaccaag tcaagatact caaagttatg atccttacgc tggacaggaa caaaatggtt
     6481 atggttatga ccagaataat gagtatggaa caacaagtgg gtactagaaa aaaatagttt
     6541 ggttaataaa gagtgccacc taaattagac aaaaaatcta acttaggtgg cactttttct
     6601 atgtgttaaa ttacaggacg tctcttttta gcgcttagtt taaaaaataa attgaataat
     6661 tcaatagagt tgcgaatagt acccataaat aataaggaat catgagccac attgccaggc
     6721 gatgatgcag ccacaactga tacataagca ctgacaagaa aataactaaa agtgtaatat
     6781 cgattgctgc aatgaaaata tttcttaaat taaaaaatag agcagaccat ataaaattaa
     6841 aaatgaactg aatcacaaaa agaccgacaa gattgtttcg ctgttttttg ttgttgtgat
     6901 taagtaacaa ataaagagaa atacccatca atatatacag taaggtccac atcggcccaa
     6961 atatccagct aggtggtgca aatggtggaa gttgcaaaga atagtaatat tttccgggat
     7021 ttccgctaag caaccctgat aaaaagccta atatgacaat tcctataaca caaacccaaa
     7081 aacgaatatc ttttatcatc ttcattttac taactccttt ctataatatt agtttaccat
     7141 gaaggctcac agcaagacct gtatttagtt tgtgaagtaa gaaaaaaatt gataattgtt
     7201 gttattaaaa agttgaacat ttgtttatat gaatgatgtt tttgaaaaag atcatatgat
     7261 ttgattctca tgttttctat ttgtactttt ctcgtctact tctgttataa tctgcatctt
     7321 acttttttca ccttttttac ttcaacataa aattataaaa gcataatgtt tgtgttaata
     7381 caataaagcg tttacaatgt ggttatcaaa tgaaggaggt ttctacatga aaaagattag
     7441 tacgttattg tttattgggt tagttagttt agggttgttc ggttttagca ttccaggttt
     7501 tgcgcatggt tatattactt ctccaggaag ccgtgcatac ctaggaacat cagcagcagg
     7561 aaacttaaat caaaatgtcg gaagagcaca atgggaaccg caaagtatcg aagctaccaa
     7621 aaatacattc attgatggaa aaattgctag tgcaggagtc agcggctttg agcctttaga
     7681 tgaacagaca tctaacagat ggcataaaaa catggttaat ccaggaacat taaatattac
     7741 ttggaattta acagcacaac atcggacaag tacttgggat tactacatta ccaaaccaac
     7801 ttggaatcct aatcaacctt tgaaatttag tgattttgaa ttgatcacaa aaatagacga
     7861 caaagcaact gttccaccaa aaacagtcaa ccaaacgatc acacttccgc aggatcgaaa
     7921 aggatataat gtgattttag cagtatggaa tatcagcgat acgacaaatg cattttatca
     7981 agtgatagac gtgaatatcc aataataatc aaaaagggct gtgacaaaaa ctatgtcaca
     8041 accctttttt taaataaata gtgtcctcct gttaactctt cggtcacaag tacagtattc
     8101 ataaaacatg aagagctatt tttgtttggc tgttcttatt acttgataca gggcagactt
     8161 tttcacaacc tctttcattt agtcagcgag tctcgtcatc ttcacgacaa cttcacaacg
     8221 tgcagtctga ggaaacatgt cgacggactg taaatattca atcttgaact ttttacttaa
     8281 attaaccaga tctctggcaa gtgtagaaac attacaggag atataaacaa gtttttttgg
     8341 agggtatttc aataatgatt ggatcaatgc gttatccaaa cccgtacgtg gtggatctac
     8401 gatgatacca tcaggctgaa aaccttcatt caaccattta ggcagaactt gctctgctgt
     8461 cccgacttca tatcgagtgt tgtgatatcc taatctttcc gcattttttt tgcatcagcg
     8521 attgcttgag gaacggtatc cattccccgt acttctttgg cttgttttgc tacacttaag
     8581 ccgatcgtcc caactccgca ataagcatcc acgatcgttt cattaggctg gacatctaat
     8641 gctttgattc cttcgccata aagcaattcg gtctgctgag gattgagttg aaagaaggca
     8701 cgaggagaaa gatcgaaagt cacttcattg atttgttctt caatggcttc ttttccccat
     8761 aagtggatcg tttcatcccc catcacgaga gacgtttttt gtgcctggac attttgcatg
     8821 attgaaacaa cttcgggcag tcgttcattg atctcacgga tcattgcgtt tttttgcggg
     8881 aattttttac tgcgagtaat aaaaacaact tgtaactccc cagttttaac accgattcta
     8941 accatgattg tgcggaagat tccactgttt gtccgttcat catagatggg tgcatcaaat
     9001 ttattcaata gttgaacaac agtattcatt actttttgtg ttcgaggttc ttgaaccaag
     9061 cagtctgtta tagggactaa ctgatgagag tttgcttcgt ataaaccagc ttcaattttt
     9121 tgagtctgct tattttttcg taactgaaat tgtgctttgt ttctataatg ccaaggctca
     9181 tccatcccga tcgtcggcaa aagttgataa gatcgaaagc ctgctggttt gaatttttcc
     9241 aatgcttgca aaagcagatc ctttttaaaa tccaattgag cttgataagc taagtgttgt
     9301 aattgacagc caccgcattc atagtaaaca ggacatggtg ccactacgcg atctttgctt
     9361 gtttttttga cttttattaa ttctccttct gcatagcgag gagttgcttt cgtgattttc
     9421 actagtactt cttcttttgg tagtgcatat ggaacaaata tgatcaaccg tttgaaataa
     9481 ccgattcctt caccatttat gcctaaacgc ttgattttca aaggaaccgt ttgtccagtt
     9541 ttgacaattg tttctgccat aagtatctcc ctttttcttt tttctgtggt ttattctaac
     9601 atataatacc tgattacggg gattttctgt ggtatgatag agaatatatg ttcgaggagg
     9661 atgtttatgt taaccgttac gagaatcagt aaaggcaaag gccctttcta tcgcgtagat
     9721 ttatctgaag gagaagcttt acaagtatct gaagatgtat tagtacgcta tcgattatta
     9781 aaaggacggg aattagacga agaaactatc caagagatca agaagagtag cggagctgat
     9841 ttcggttttc acctagcaat gaattactta agttatcagt tgcgatcgga aaaagaaatc
     9901 cgaacatact taaaagaaaa ggaaatcctt caagaagatc gaaataaaat cgtagcccgc
     9961 ttaaaagaat tggaccttgt cgatgatttg gtctatgggg aaagttatgt gcgcacgaat
    10021 atgcgcttaa gtgacaaagg accaaagaaa ttagcgcagc agatgcagca aaaaggtttg
    10081 aaacctgaaa tcattgaaca agcgctcagc caatatacat ttgaagacca agttcaaaat
    10141 gcacatcaga cagccgaaaa agcgtttgga aaaaatcacg gaaaaagcca aaaagaatta
    10201 ttgagaaaaa tccaacaaac attgatgacg aaaggctttt ctcaagaagt gatccaacaa
    10261 gcgatagctg atcttccgca agaagcagat caagaaatag aatatgatta tttagtcaaa
    10321 caaggagata aactatggcg aagaaattta aggtttgaac ctaaaaaaag aaatctaaaa
    10381 gtaaagcaaa gcttatatca aaaaggattt gatttggata tgatccagcg attcattacg
    10441 gaaaaggaag aggaaagtga ataaagaatg ggaaaaatgg acagataaag aaacaaaaga
    10501 atttcaagat cagttcattc aatggtatga acaagaaaaa agaaacctgc cttggcgcta
    10561 taatcgtgat ccttatcgta tctggatctc tgagatcatg cttcagcaaa ccagagtaga
    10621 cacagtgatc gattattttt atcgtttcat ggaatggttt cctacaattg aagagctagc
    10681 aaatgctcca gaagaaaagc ttttaaaagc atgggagggc cttggttatt actcaagagc
    10741 ccggaacatc caagctgctg ctaaacagat catgtcagaa tttgatgggg aaatgccgca
    10801 aacgcctgaa gaaattagct cattgaaggg aataggacca tatacgacag gcgcgattgc
    10861 aagtatcgca tttggacttc cagaacctgc agttgacggc aacgtgatgc gagtagtcag
    10921 cagattgttt tgcattgaag cagacatcgc aaaagcttct agcaggaaaa tctttgatga
    10981 agcgatgcgg aaaatcattg atgaaaagca tccaggtgaa ttcaaccaag caatgatgga
    11041 tctaggttca gctatctgta caccaacttc tccaaagtgt gagacttgtc cgatccaagc
    11101 cttttgttta gctaacaaac gaggaatcca aacgagtttt cctgtaaaaa caaaaaaagc
    11161 aaagccaaaa gacgtttatt atatcagtgc agctcttcaa aatcattctg gagcgtatta
    11221 ttttgaagaa agagatagcc aaaaattgct ggcgaatatg tggacatttc caatgatgga
    11281 agtgacacaa gaggagtatg agcgattgaa aaaagaatgg gaaacaaagc cagaaatcga
    11341 tctgtttgat gacctagtag cagaagaaga gcaaaatctc ccatttgaaa agcaggaact
    11401 ctttgtttgg cagacacgac atttaggaga agttactcat atttttagtc atctgaaatg
    11461 gcatgttctc cttttttacg gacgggcaac cgagggagca gaacaagaat ttaccgagaa
    11521 caaaacttcg aagtggttga agcctgatgc atttgattcg gtcgtttttc ctaaggtcca
    11581 aatgaaactg gtagatcagt tagagaaaaa tcgaaacaat aggaatcctt tctaggcaaa
    11641 gctcattttt attgatataa taattatgat gtcggtgtaa tgaacaccca aacacaaagc
    11701 acaaaatgct gcttaaggaa gggttgctat gggagttcca aaagaaggag agtttgtgac
    11761 gatccaaagt tacaagcacg acggcaaatt gcatcgaacg tggcgagata ccatggtatt
    11821 aaaaacaagc gaacactcta tgatcggcgt gaatgatcac acattagtca ctgaatctga
    11881 tggacgccga tgggtaacgc gcgaaccagc gattgtttat tttcataaaa aatactggtt
    11941 caatgtaata gcaatgatca gagaaaaggg ggtttcctat tattgtaatc tagcttcacc
    12001 ttttttgctg gacgatgagg ccttgaaata tatcgactat gacttggata tcaaggtatt
    12061 tcctgacggc gagaaacgac tattggatgt cgatgaatat gagatgcaca gcaaaatgat
    12121 gaattacccg aacgatattg acttcatcct aaaagaaaat gtgaagattc tggttgactg
    12181 gatcaataat ggagatggcc cgttctcgga aggctatatt gatatttggt ataaccgtta
    12241 caagcaattg tcgcgtaagt aaacacaaaa aagaacagta agccagtgag agatttttct
    12301 caaaagcttg ctgttttttg cttttttcga aataaatttt tataaagtct ttttcatata
    12361 aatatgaggc atgccagcat cttcaaaagg atcgccgtaa gctgtatatc ctagtttttc
    12421 gtaaaaagtt tcagctgtgg actgtgcccc taataaaatc gtattatagc cttgattctt
    12481 agcaaagttt tctgcttctt caatcaatat ttttcctaac ccttggtgtc tgtattcaga
    12541 aagaatcgcc atccgctgta atttcatttt tccgttttct aaaggcaaaa gacgtacagt
    12601 tccttgcggt tcttttttat ctgagtacag gacgaagtgg atacaatggg cttcatcttt
    12661 gtctatttct cgagacaaag gcacaccctg ttcgactaca aaaacttgat gcctgatccg
    12721 tacagcatct aagtaaatat tgctcattgt atcttttgtt tgtacaactt tcatggtcta
    12781 gccaccttcc tttcgtatag tatactggaa aataaaacaa ataaaaagta tggcaagttt
    12841 tcaaaaataa aaaaagaata aaagaatttt taacgaatat aatatatact agtaagaaag
    12901 aaaggaggaa atctattgtt tgaaaaactt agacagtcta aactaatgtt ttggtcgctt
    12961 gaattattga tcatagctgc attgatcatg atttcatcag aaataaactt tattttcgaa
    13021 ccgatcggga catttttttc cacgttattt gcacctgtac tgattgcagg ctttctttac
    13081 tatttattga atcctattgt caagctgttg atgaaagcaa aaatcaaaag aatatgggct
    13141 gtcgcaattg tgctgctcct tttagttgca gcaattattt ggattttact tagtgtcatc
    13201 ccaagtctag tacagcaaat ttcctcattg gcatctaata tgcctgattt catcaaacag
    13261 gtagaaagct ggttaaaaga ggtagccgaa ttgcctttgt tcaaggaagt agatatcaat
    13321 aaatattttg agcaattaga catttcttac gggacaatca ttcagcaatt ccttagtgga
    13381 gtatccaata gtttaggttc gatcgttgga acgatcgctt cggcaaccgt agtaatcatt
    13441 acagcaccat tcatcttgtt ctatatgttg aaagacggag aaaaactagt gccaaacatc
    13501 caacagtttt tcccagaaaa aagaagaaac caaattgtgg agttattggg gcaactgaat
    13561 aaaacattgg ctaattacat tagcggacaa gcaatcgaat gtttattcgt tggtaccttc
    13621 acatttttag gatatatggt aattggtgtg gattatgctt tcttatttgg ggtcattgcg
    13681 ggattgacaa acctaattcc atatttagga ccttatctag gactagcacc tgcatttcta
    13741 gtaacagtct tcaatgatcc ggtaaaagca ttactttgtt gtgtggttgt gctaatcgtc
    13801 caacagttgg atgggaatat catttatcct aatgtaattg ggaaatcact gaaaatccat
    13861 ccattaacga tcattatcgt tcttctagta gctggaaata ttgccggatt gcttggtatc
    13921 ttcttaggtg ttccttttta cgcaatctgc aagacgatca tttcctatat aatcaaaatc
    13981 gtcaaagaag acaagcaaaa tgaaaacaag aagaaaattg ctacgacctc gtaggtagtt
    14041 ttagtacact tgtttttatt gcaaagaaaa ttgctttgtg ataccatttt aacgtggcta
    14101 tagtgccacg tttttttcta tcgtaaacta aaaattaatt ttataaggag agaatgcgat
    14161 tatgaatgct gaccctgaga gtcagtcgct gttagcgcag attttattat tgatcgtttt
    14221 gacattgatc aatgcttttt tagcagcttc cgaaattgct gttgtttcga tcaataagaa
    14281 tcgaatcgag caaaaagctg atgaaggaga tgtgaaatct caaaagcttt taaaaatatt
    14341 gcagaatcca aataatttcc tatcgacaat ccaagtagga atcactttgg tcaacatttt
    14401 gtctggtgct tcactagcta atactttatc ggaacggtta gctccggtat taggtggcgg
    14461 cacagcggca aaaaatattg caaatatcat tgtgctggct attttgacct atgtatcgat
    14521 tgtttttgga gaattgtacc ctaaacgtat tgctttaaat aaatcagaag aagtcgcaaa
    14581 gttcacttca gggctgatac gcttgattgg tgtagtagct aagcccttcg tctggctgct
    14641 ttctgcttcc acaagtttat tggcgcgtat cacgccgatg acttttgatg atgaagattc
    14701 aaaaatgacc agagatgaaa tgcgttatat gcttgaaaac gaaggcgtat tgaataatga
    14761 agaattagaa atgctccaag gggttttttc tcttgatacg aaagttgccc gagaagtcat
    14821 ggtcccacga acggatgcat ttatgattga tatcaacgac actgtggaag aaaatgtgaa
    14881 tgaagtttta tccgaaaact attcaagaat ccctgtttat aacgaagaca aagataaagt
    14941 agtcggaatc cttcatacaa agaatttact aaaagctgcc cataaattcg gctttgataa
    15001 tttagatatc aagaaaatca tgcaggagcc tttattcgtt cctgaaacgg tctttattga
    15061 tgatctgtta tatgaaatga aaaagacgca gaatcagatg gctattttat tagatgaata
    15121 tggcggcgtc gttgggttag caacactaga agacctttta gaagaaatcg tcggagaaat
    15181 cgatgatgaa tcagatgaag ttgagaatct ttatgaaaaa atcgatgaac acgaatatat
    15241 catccaagga cgtatgctga ttgatgagtt caatgaagct tttgacagtg atctgcatat
    15301 gagtgatgta gatacgatgg ctggttattt gattacagca ttaggcatga ttccggatga
    15361 aggcgaaaag ttatcgtttg atgtcgataa tattacgctg gtttctgaag aaatggaagg
    15421 ttctcgaatc cttaaaatcc gtgtcatttt tcatgatccg gaagaaacag aagcggaacc
    15481 tgaagaagaa cgaagatact tcagaaaaga attcgaagat gacgagccaa gaagataatt
    15541 ggaaacttgg ttatgaaaga cgtgttgctt gaataaacaa gcaacacgtc ttttctttta
    15601 gtcagctgac aaaaaaatat ttgactctta tggtttggtg gctttttcat tcgctgaatc
    15661 catgctatac tgattcagtt gtagtagttg acaaaggttg tgaaaaagct atcctgcatt
    15721 aagtaataag agcagccaag caaaaacagc ttttcgtatt tttggcttgg gtgggcttat
    15781 tgctgatagg ctgtctctag aacgccgttt actcggaaaa agagactgct acacggcttt
    15841 tgtcacagcc ctatatgaaa ttgtctttct ttaagagatc ggacaatctg tgcctagaga
    15901 aaatataaat aattgaatgg aagaaatgga gttaggttat gaataatcca aaattaaagc
    15961 aacaagtgga caatcgcaga acttttgcga tcatttccca tccggatgct gggaaaacaa
    16021 cgattacaga acaattacta ttgtttggtg gggctatccg tcaagccggg accgtaaaag
    16081 gcaaaaaaac aggtaatttt gccaaatcag actggatgga aatcgagaaa caacgtggga
    16141 tttctgttac tagttctgtt atgcagtttg attatcaagg gaaacgagta aatatcttgg
    16201 atacaccagg acatgaagat ttttctgaag atacttatcg tactttgatg gccgtggata
    16261 gtgcggtcat ggtaatcgat agtgcaaaag ggatcgaagc acagacaaag aaattattcc
    16321 aagttgtaaa aaaacgtggc atcccgatat ttacttttat caacaaacta gatcgtgatg
    16381 gtcgtgaacc attggaattg ttagaagaat tagaagagct attagatatc gaatcttatc
    16441 cgatgaattg gccaatcggt atgggcaaag ggctagaagg tctttatgat atctaccata
    16501 atcgtgtaga gttttatcgt ccggaaaatt atcaggatga acgattagta gaattggatg
    16561 aagatggact gcttcccgaa aatcatcctc taactgaaaa ttccttatat gaacaagtct
    16621 tagaagaagt agaactaatc aaagaggctg gagatgcatt taatcaagaa aaaattgctc
    16681 gtggcgatca gacaccagta ttttttggtt ctgcattgac taacttcggt gtacagactt
    16741 ttttagagac tttcgttgaa ttggcaccag ctccttatgg acacaaaaca caagatgatc
    16801 agatggtaag tccttatgag gaagaatttt caggtttcgt attcaagatc caagcaaata
    16861 tgaatccagc ccatcgtgac cgaatcgctt ttgtccgaat ctgttctgga acattcgaac
    16921 gaggaatgga tgtctggttg gaacgtacaa ataaaaaact gaaattaagc aatgtcacac
    16981 aatttatggc agattcgaga gaaaacgtcg aaaaagcagt agcaggcgat atcatcggtg
    17041 tatatgatac aggcaattat cagattgggg atacattgtt cgaaggaaaa ctaaaagttg
    17101 cttatgaaga actcccttca tttactccag agctgtttat gaaagtgact gcaaaaaatg
    17161 tcatgaaaca aaaatccttc cacaaaggaa tctatcaatt agttcaagaa ggagcgattc
    17221 agctttataa aacatatcta acggaagaat atatcattgg agctgttggt cagctacaat
    17281 tcgaagtatt ccaatatcgt atgttaaatg agtataacgc cgaagtaatc atgtctccaa
    17341 tgggacacaa aatcgctcgc tggatcgatc cagaagattt ggatgagaag atgagttcaa
    17401 gtcgcaatat cttggctcgt gaccgtttcg accaaccgtt gttcttattc gagaaccaat
    17461 ttgcagaacg ctggtttgcg gataaatatc ccaatgtaaa attaaaaagt ttgatgtaaa
    17521 gaagtcttga cacaagctgc cctgcatcaa gtaataagaa tagccaaaca aaaacagcct
    17581 ctcatatttt gtttagagcc gtgacggatt ttccgtgacg gctcttttta ctatattaaa
    17641 atcatagaaa tgtctaatca aaaaaatata aaaattattt tgcgtacata tgattaaaga
    17701 aaggagagtg tgacacatgg aaacagaatg gcaaagacgt gaaagaaaaa aacagaaaaa
    17761 agaagagatg ttacgattat gtcgattatt agatgtaaaa gactgggaca aaaacgagca
    17821 aattgcacaa aaagtacgat caatcatcca taaagaggaa aaagttaaaa ataaagacac
    17881 gcgtagaact gaaaatgaaa agagaaaagt acaaaagaaa agagaaaaat caaaaagcta
    17941 gaaagaaaaa gaggctgaga cagaagcgtt taactccaag aaataagctg gaattcacaa
    18001 aaatttgaaa agcaattttc gtgaatttca gcttatttcc gaaggagttg cttctgcttt
    18061 cgccgtttat acgtgtttag agcgtgagac aaaagtgttc ttta
//
LOCUS       DAPBAF010000052        17526 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.052, whole genome shotgun sequence.
ACCESSION   DAPBAF010000052 DAPBAF010000000
VERSION     DAPBAF010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 17526)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17526)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17526
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.052"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            <1..525
                     /gene="scm"
                     /locus_tag="RD451_002284"
     CDS             <1..525
                     /gene="scm"
                     /locus_tag="RD451_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HDT7567511.1"
                     /translation="TSASSDSTDTTSTTSDSTDTSASSDSTDTSTTTSDSTDTSASSD
                     STDTTSTTSDSSDSSTTTSDSTDTSASSDSTDTSSTTSDSSDSSTSSDSTDTSSTTSD
                     TRHASVSFSKTSSDNRTNFNLTNKTSNDNGNKSKRALPKTGSQSNNWITLAGVILLVI
                     GLRITFMSYKKSKR"
     gene            complement(680..1666)
                     /locus_tag="RD451_002285"
     CDS             complement(680..1666)
                     /locus_tag="RD451_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HDT7567512.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(1689..2255)
                     /locus_tag="RD451_002286"
     CDS             complement(1689..2255)
                     /locus_tag="RD451_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HDT7567513.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKRDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            complement(2269..2685)
                     /locus_tag="RD451_002287"
     CDS             complement(2269..2685)
                     /locus_tag="RD451_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HDT7567514.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            complement(3142..5076)
                     /locus_tag="RD451_002288"
     CDS             complement(3142..5076)
                     /locus_tag="RD451_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDT7567515.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            5357..6313
                     /locus_tag="RD451_002289"
     CDS             5357..6313
                     /locus_tag="RD451_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HDT7567516.1"
                     /translation="MEWWGIKMKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSES
                     STAQSSTAKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKY
                     DNVNENGESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSS
                     ESFQNYAQQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGK
                     VTESNFDYIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPAN
                     VEVVTGATHSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            6403..7506
                     /locus_tag="RD451_002290"
     CDS             6403..7506
                     /locus_tag="RD451_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HDT7567517.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            7519..8472
                     /gene="menA"
                     /locus_tag="RD451_002291"
     CDS             7519..8472
                     /gene="menA"
                     /locus_tag="RD451_002291"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HDT7567518.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFALVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(9407..10753)
                     /gene="gor"
                     /locus_tag="RD451_002292"
     CDS             complement(9407..10753)
                     /gene="gor"
                     /locus_tag="RD451_002292"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HDT7567519.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFRGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(10887..12140)
                     /locus_tag="RD451_002293"
     CDS             complement(10887..12140)
                     /locus_tag="RD451_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HDT7567520.1"
                     /translation="MMKEMTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAY
                     GLRSRAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISA
                     VIVSDPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVA
                     EIRKNTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFG
                     QERNSLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNV
                     YKAAVDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVY
                     KFVGEVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRA
                     PNPMMILTMPVAQPVKPGDMIRKRK"
     gene            complement(12146..13069)
                     /locus_tag="RD451_002294"
     CDS             complement(12146..13069)
                     /locus_tag="RD451_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HDT7567521.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(13290..15782)
                     /locus_tag="RD451_002295"
     CDS             complement(13290..15782)
                     /locus_tag="RD451_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HDT7567522.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(15789..16256)
                     /locus_tag="RD451_002296"
     CDS             complement(15789..16256)
                     /locus_tag="RD451_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HDT7567523.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
     gene            complement(16392..16465)
                     /locus_tag="RD451_002297"
     tRNA            complement(16392..16465)
                     /locus_tag="RD451_002297"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(16429..16431),aa:Arg,seq:acg)
     gene            complement(16523..16596)
                     /locus_tag="RD451_002298"
     tRNA            complement(16523..16596)
                     /locus_tag="RD451_002298"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(16560..16562),aa:Pro,seq:tgg)
     gene            complement(16618..16691)
                     /locus_tag="RD451_002299"
     tRNA            complement(16618..16691)
                     /locus_tag="RD451_002299"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(16655..16657),aa:Arg,seq:acg)
     gene            complement(16702..16787)
                     /locus_tag="RD451_002300"
     tRNA            complement(16702..16787)
                     /locus_tag="RD451_002300"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(16751..16753),aa:Leu,seq:taa)
     gene            complement(16804..16875)
                     /locus_tag="RD451_002301"
     tRNA            complement(16804..16875)
                     /locus_tag="RD451_002301"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(16841..16843),aa:Gly,seq:gcc)
     gene            complement(16887..16959)
                     /locus_tag="RD451_002302"
     tRNA            complement(16887..16959)
                     /locus_tag="RD451_002302"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(16924..16926),aa:Thr,seq:tgt)
     gene            complement(16977..17058)
                     /locus_tag="RD451_002303"
     tRNA            complement(16977..17058)
                     /locus_tag="RD451_002303"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(17022..17024),aa:Leu,seq:tag)
     gene            complement(17066..17138)
                     /locus_tag="RD451_002304"
     tRNA            complement(17066..17138)
                     /locus_tag="RD451_002304"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(17103..17105),aa:Lys,seq:ttt)
     gene            complement(17142..17214)
                     /locus_tag="RD451_002305"
     tRNA            complement(17142..17214)
                     /locus_tag="RD451_002305"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(17179..17181),aa:Val,seq:tac)
     gene            complement(17228..17343)
                     /gene="rrf"
                     /locus_tag="RD451_002306"
     rRNA            complement(17228..17343)
                     /gene="rrf"
                     /locus_tag="RD451_002306"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            complement(17438..>17526)
                     /locus_tag="RD451_002307"
     rRNA            complement(17438..>17526)
                     /locus_tag="RD451_002307"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT         5130 a         3731 c         3155 g         5510 t
ORIGIN      
        1 acatcagctt caagtgacag tacagatact acctctacca caagtgatag cacggacacg
       61 tcagcttcaa gcgacagtac ggatacatct accacaacaa gtgatagcac ggacacgtca
      121 gcttcaagtg acagtacaga tactacctct accacaagtg atagctcaga ttcatctacc
      181 actacaagtg atagcacgga cacgtcagct tcaagtgaca gtacagatac atcctctacc
      241 acaagtgata gctcagattc atcaacttca agcgatagta cagacacgtc gtctaccaca
      301 agcgatacac gtcatgcaag tgtctccttc tcaaaaacaa gttcggataa caggacgaac
      361 tttaacttaa ctaataaaac aagcaatgac aatggaaaca aatcaaaaag agcacttcct
      421 aaaactggaa gtcaatcgaa taattggata acactcgcag gcgttatatt acttgtaatc
      481 ggtttaagaa tcacttttat gagttataag aaatcgaaaa ggtaaaaaaa tattcaagat
      541 aaaaaagagc aacgtcgcta acggacgttg ctctttattt ttgcttttta tcataaatac
      601 aagaactaca attcaatttg tcaaaaaaca cgtagatttc cttctgagaa atttatttac
      661 gtatcgaacc tttccctatt cagtctttgc gatccaaaat cagttgggta agggaaaaga
      721 gattctcttt tgttcgaaga gaggtggcag gtaatttctt tatttccttc aaagcctttt
      781 ctgtgtaaga ggccgctaac ttcctagctt cttccacgcc tcctgtatgt tcaacgattt
      841 tgcgtacggc gtcgacatct tcttctgtca ttgccgcttt cttctctaaa taaggtagta
      901 gctttggttt gtttttttgc aaagagtaga tcaacggtaa agaatagacc ccttgacgca
      961 tgtcttctag tacaggtttg ccgatttcct ggctctcttt tgtataatct aaaatatcat
     1021 cgataatctg aaaggccatc ccgatagaaa gtccgatatc tcctgctttt tttgcgaagc
     1081 gctcgcttgt tccactttca aaagcgccaa cagaacaact taattggaac agttcagctg
     1141 tcttacctga aatattttcc aaatattctt ttacagaaag ttcataatta tagcgatcat
     1201 ccatctgccc taattcgcca ttcaatactt tttccatact gcgagaattc aattggagac
     1261 ttttcaagga agtggagtaa tcagacaata gtttaaaaca gcagacaaat aaatagtctc
     1321 ctgcatagac agaaacgaca ttaccaaact gactacggat attaggctga ccacgtcgca
     1381 gatccgcttc atcaacgata tcatcatgga tcagtgtggc cgtatggagc atttcgatag
     1441 aagctgccaa agcgatggct ttgtctcgat cttgctctgg tccaaattgt gagaacaata
     1501 gctgataggc aggacgcaac agctttccgc cggcatggat cgtttctttg attgcttgtt
     1561 cgacaggttt gtttttcagg cggacagttt cttccatccg ttttagtgtt tctgtcaatt
     1621 ctttacttaa agcaggatag ttttcccaca ttggatgtag cttcataaaa aaactccttg
     1681 tgtgacgatt attttttggt aaacattggg ctccattttt gtttggttcc ctgctcataa
     1741 tctttttgga atcgttgaag tgtctgcaca tgtcgtaaaa gataattcgc tgcgatcccg
     1801 attgcaatcc ctgataaaat ccctaaaact gaaaggactg gcaagtacaa catgactgtc
     1861 catgattgtg caatgaaaga agccatcaaa agctgtccga cattatgcat gaaaccgccg
     1921 gccgcactaa ttccgatgat actgacacgt tttggtccta attgcttgac caataacatt
     1981 ccaaaataac taagcaaagc accactcata ctataaagga atgtggaaat cgttccgcct
     2041 agcaaagtag tcaggaatag tcgtagccaa agtagtaaga agctgtctcg ttttttcatg
     2101 gtaaaaatgg caacgatcgt gattagattg gctaagccta gttttgcacc aggcgcaaaa
     2161 gaaaaaggat aagggatcat attttccaat aaaccaatga tcactccttg tgcaacaagt
     2221 agcgaaatat aaatcatttt ttgtaattta ctcatggtgt gtgaaggtct aataaatcag
     2281 actgtcttcg tcacctccat ctgttgaacg gacttcgatc actaatttat gtggcaaaca
     2341 gacgatggtt tcgccatttt tcgttgccca gcctcgacgt acgcagatct ggtcatcgca
     2401 atctgcttct tttatccgta ctcgatcgcc atctatctcg atcaagttat aatctccgtg
     2461 ttcatctttg taagtatatg tgttgctctc ttctccagcc atcaaaggga atgttttgat
     2521 ttctgtgcca tccacacgca gtaccgcttc tttttctgct gttgcggtgt tttgctgaag
     2581 accaaaaatc atgactggta aaaaagaaag aacagtcaaa agcaaaataa taaaaacatc
     2641 ccaaggtttg agcagacttt tttcagcaaa ttctttaagg ctcatttttg ttctcctttt
     2701 tccagattaa ctcacccaat tttagcataa aaacaagagg ttgtgacacc tgtgtcttgc
     2761 tttgagtaat aagaacgaag aatagaaaac agctttccat gttttctaat tctttgggct
     2821 tattaccgag aagcagcagg tggaacaccg tttataacaa gaggttgtga cagaagtggg
     2881 caacttcaag aaataagaag gaatttacga aaattacttt tcaagttttt gtgaaatttc
     2941 ggcttatttt tcgaagaagc tacttctgga acaccgttta taacaagagg ttgtaacaga
     3001 ggttgtgaca cctgtgtctt gctcatggag gcttatctcg ggcatcttat tcctttaatt
     3061 ttacataaaa aggaggctgt gacggtttgt ctcagcccct ttctattgaa atcttgcatt
     3121 caaataacgt tctttatcta tttatttctt gccgtactgg gaacttggtc taccgtacca
     3181 ccaattacct agtgtacgtt gtagccatgg aattacccag cgatccaacc caatcgcacg
     3241 tccggaaccg ttcatcaatg cgaaagcaac aaaaatgaac caaatgttta cccagtaaaa
     3301 catgcctgat aagcagaacg tgatcaccaa tacaatcgtt gtcgcactgc atagccatgt
     3361 gaataatcca gcaatcaatg ctaatgccaa ggcaatttca aagaatacca tgaatttttg
     3421 gaagaacatt gctacatcat tgtttggcat gatcacttgc atgatctttg tgaaccagtc
     3481 tggtgacttc tcaatcacag ccattggttc ttcaccgtat gcataactca aaccaaaatg
     3541 tgcagcttga gtcgctgctt ctccggcact tgcccctgct ccgctggcag ctgtggttgc
     3601 atcaccagca gcagaagcac cactggcaac atctgttaca ttgtattccc atgtccaagg
     3661 gaacacactg tttccagtga accatgatcc ttcaccaaac caagtacttg gtttgaacac
     3721 ttcaccattc ccaatgattt ttttggaagc ttcaacgaac caaactaaac catagaaaat
     3781 acgaagtggc acactccata agacattgcc gtaacgagaa gaatgtcctc gagtcacgtt
     3841 gcgatcatct ttgatatgga aaaactcatg cattaaatat tggaacatat aataaccaga
     3901 acgaatatca aagaagtatt tcaaattcac gatatgtttc attacgatag ctaaaaatcc
     3961 gcttaaatgg atcttatcaa ataggttagc taccccccat ttggcaccaa tagaaaccat
     4021 aaatccttga tagtttcctt taaatttatg cttttctccg cctttgatcg aagccacgat
     4081 attcgctgcg gctgtgtgtc ctgtttgttc agcagcttga acgatctgcg gtgtcggtgt
     4141 tcctgggaat tcttcataaa agactaaatc accaatgata tagatgtttt tatcttcgta
     4201 gccttttgcc tgcatatatt cattggcgat caaccgctgt ccgcgtgctg attctaatcc
     4261 aaagtcagca gcgtcagaag ttcctttgac accagctgtc caaatcagtg tgtgagtcgg
     4321 aatgttgcgt ccgtctttca atttgatatg atcagcagcc acttctacga ttggtgcatt
     4381 caataataat tccacgttgt gcttacgcaa atagcgttca gcttttgcag catcatttcg
     4441 atccaacata ttcaagatcg tcggcattgc ctctacgacc atcagtgtga tttcgtttgg
     4501 atctaattta taatctttgg ctaggcgatt tttccagtcg atcagttccc caatcatttc
     4561 aataccggta aatccagaac cacagacaac gaaagtcagc atggctttac gcagttcatc
     4621 atctggttcc aatgcagctt ttgctactgt cttctcaata tgttcccgaa tccttacaga
     4681 atcttcaaat gaccaaaggg tgaatccgtg tgctttgaca ccaggtgtac caaagtcatt
     4741 cggctctccg cccattccaa ggatcagctg atcaaaagga taggaaccta atttggtctt
     4801 gacgattttt cgttctttat cgataccgat tacagtgtct gtgacaagtt gtacattctt
     4861 ttgacgagca aacaaatgct gcagatcgta ttggattgct tctggttcta cacgtccgcc
     4921 agctacttca tgcaactcgg tcatcatagt atggtacgaa tgacgatcga tcagagtaat
     4981 tgctacatct tcttttttca gtttctttgc caagtatttt gtagctgaaa caccggcata
     5041 tcctgctcct acaacgacaa tattttgctt tgccattgat catccgctcc ttatagacta
     5101 tctatataat gaatatatga taattctttt agtttgatac ttattacaca atctccatat
     5161 attatataga tgttctgttc ttttgtctaa ctccttttgg atttttttca aattttaaaa
     5221 taaagcgttt tttcacgaaa tttgctgaaa gaaaacgttt gaaatattac atgggttatt
     5281 tatcaaaaat agttgactta taggctaaaa agattagaat gtataatgaa tcacaaagaa
     5341 aaattgtgga ctagaaatgg aatggtgggg tattaaaatg aagaaaaaac gttttgtaac
     5401 tggatttgcc gtattagcat tttcagctct agtgttaggc gcttgcggcg cagatgacaa
     5461 cggaagctca aactcttctt ctgaatcatc tacagcacaa tcttcgactg caaaaagcac
     5521 aacagaatca tctgcaaaag ttgtagctgg cggagatttg caagacggca catataaatt
     5581 agaagaaaaa aattattcaa atggttaccg tgcagtcttt gaaatggttg taaaagacgg
     5641 caaaatcact gaatcaaaat atgataacgt caatgaaaac ggcgaatcaa aaacaaaaga
     5701 tgcagaatac aacaaaaaca tggaagcaaa atctggcaca aacccagaaa aatacattcc
     5761 tgagttgaat gaccaattct taaaagcaca aagcgcaagc ggtgtggaag tcgtaactgg
     5821 agctactcac tcatctgaaa gcttccaaaa ctacgcacaa caattgatcc aagctgctca
     5881 agctggtaac acagatacaa tcgaaatcga caatggtgct gatttgaaag acggcactta
     5941 caagcttgaa gaaaagaact actctaacgg ctaccgtgtg caattcgaaa tgacagttgc
     6001 tggcggcaaa gtaactgaat caaactttga ttatatcgac aaagacggta aatcaaaaca
     6061 agatgataca gaatataatg aaaatatgaa agcaaaaagc ggtacagaac caaaaactta
     6121 catccctact ctgaacgacg aattcgtcaa agcaatgggc gaagaagatg gctcacctgc
     6181 taatgtagaa gttgttacag gtgctacaca cagctcacat tcattcatca tgtacgcaca
     6241 acaattagtg aatgcagctg aaaaaggcga cactcaaaca atcgaagtag ataatatcgt
     6301 aacagaaaaa taatcacata atcatactaa taaaagttgg agggtgggac gatagccaga
     6361 ttaggcagtc gtctcacctt tcaaaatgaa gagaggaaaa agatgcggaa aaaactacta
     6421 ttttccttaa tcacactggg catctctttt atggtgctaa ctggctgcag caactcagca
     6481 aataaaacaa ccactgaaag ttcagcagct accaagatat tgaaagatcc atattctgat
     6541 gaacagttct tgttagggac ttacgttcgt atccgtgtgt atgatgaagg caaagaatca
     6601 gcattgaaac ctgccttcga tcgagtaaaa gaacttggtg ataaaatcac gatcaatcaa
     6661 aaaggttctg agatcgatga agtgaatgag caagctggga tcaaaccagt aaaagtttct
     6721 gatgacgtct acacgttagt caagcgggcc tacgaatata gccaagattc tcaaggcgga
     6781 ttcgatatgg cgattggtgc aatcacacaa ttatggcgaa tcggttttga tgacgccaga
     6841 aaaccttccc aagaagaaat cgatcaggca ttgaaattag tggattatca taagatcgaa
     6901 ctaaatgaca aagaaaaaac tgtttatcta aaagaaaaag gaatgatcat cgatttaggt
     6961 gcaatcgcca aaggttacat tacggacgaa gtagtgaaag tcttgaaaaa acaaggagtg
     7021 accactgcca tcgttgactt gggcggtaat gtctatgtct taggccacag cccaagaggc
     7081 gaaaaccaag actggacagt cggcatccaa gatccgaaca tggctcgcgg atctgtttta
     7141 ggttctatta aagaacggaa caaaacatta gttacctctg gaatttacga gcgttattta
     7201 gaagtagatg gcaaaaaata ccatcatttg tttgatccaa aaacgggtta tccgttcgac
     7261 aatgatatcg caagtgtcac gatcataaca gataaatcaa ttgatggtga cgggttgtct
     7321 acagcagtct tttcaatggg tgtgaaaaaa ggactggaat acgtcgaaag cgaattgaat
     7381 aacgggacgg aagcgatctt cgtgacaaaa gacgataaag tatatgtgac cgatccaatc
     7441 aaagacacct tcaaattatc ggaggactcc cattacacga tgggtgaccg ttctgaacta
     7501 aaataaggag tacgaaccat gacactaaaa atctttttag aagtagttga aatacgaaca
     7561 aaggtggcta gtgtatttcc ttttgcggta ggggtattat tctctatcgc tttttttcat
     7621 gagatacatt ggctaaacac ttttttattt tttattggaa tgctagtttt tgatttagcg
     7681 actaccgcta tcaataatta catggattat gaaaaggctc attctgaagt atataagtat
     7741 gaagaaaatg tcattggccg cagaaatcta tctcctgtat tgattcgaaa catgatttta
     7801 gctatgattg catttgtttt tgttatcggc gttattctaa cgatcaatac gggttggctt
     7861 ttacttttga tgggatttat ctgttgtttt attggagtat tctatacatt cggaccgatt
     7921 cctttatctc gaatgccttt aggggaaatt ttcagtgggg tgactatggg ccttggaatt
     7981 tttgccatgg tcgtttatgt caatacattc ggttcagatg tctatgatct gacagtcaac
     8041 ttttcatctg gacaatttgc tttggtagga aatctttggg ctatagcagc aatcgtatta
     8101 gcttccttac ccttggtgtt tacgattgcc aatatcatgt tggctaataa tttgcgggat
     8161 cttgaccgtg atattgaaaa tcatcgctat acactagttt tttatatcgg acgtcctgcg
     8221 ggaacagtct tattccagct attgatgtat gcttgctatt tcgtgatttt aatggggttg
     8281 ttgagcggta tctatgaatg gccgatcttg gtcaccttct tgaccttgcc aattgtgaag
     8341 aagcatttgg atcaattcaa gcaaacgtta ccccagccta tcagtttcag ctattccatc
     8401 aaaaatatgg tcttattcaa tgccagttat gtattggggc tattactaac aatcattatg
     8461 caagccattt aacagcatga agaggttgtg aaaaaactgc cctgcatcaa gtaataagaa
     8521 cagccaaata aaaatagctc cttatatttt tcgtttggtt gggcttatta ccgcagatgc
     8581 aagcttttga acaccgttta tcaggaggtt gtgaaaaagt cgcttagttt cgagtattaa
     8641 gaaaaatttt gtgaaaatgg ctttccacat ttttgcataa atttggctta ataccgagaa
     8701 actggctttt gaacaccgtt tatcagaggt tgtgaaaaag tcgcttagtt tcgagtatta
     8761 agaaaaattt tgtgaaaatg gctttccaca tttttgcata aatttggctt aataccgaga
     8821 aactggcttt tgaacaccgt ttatcagagg ttgtaaaatc agtgttttgt cctgagtatt
     8881 agagaaacaa atggaaaaat agttcctcat attttgccgt tttttgagct aataccgaag
     8941 gacagctgat tgaacactat ttgttcggaa aaagtgacta actatgacac aatttttttc
     9001 acagtccctt ttttcacttg atttgattcg taccagcgaa cttgacgaga actttcttgg
     9061 tttggtaact atatggtatt cttttaacat cctcgtttgc ttcttctaat ttatttatac
     9121 aaagtcacac ttttttaaac atctgttctt cgatacattt ctatttcttt taaacatcga
     9181 taccaatatt ttgaacttaa gagtgcatac caaatggatt catttactct tcgtcagtta
     9241 cgaagataat caaaatctcc aacttcccta cttatttcgt tttgagaatt atcgaagcaa
     9301 tcttacataa ataactaaaa aacaaaaaac cagaaaatca gtatactgat tttctggttt
     9361 tacatggttt gttcaataaa aagctgttgg aactgttaat attaaattat cgcatcgtta
     9421 cgaattcttc cgctcctgtt ggatggatgg ctactgtatt gtcaaagtct tctttagttg
     9481 cacccatctt gatagccacg gcaaaacctt gcagcatctc atcgacacca acaccaatag
     9541 catgtaagcc gacgattctt tcttcttttc cgacacagat caatttcatt tcgcattttt
     9601 ggcgataatc atttaatgca aagtacattg gggtaaagcg tgaacgataa actttcaatt
     9661 cattttcgcc atatttttcc aatgcttctt cttctgtcaa accaattgtt gcaattggtg
     9721 gatgcgtaaa gacgactgtc ggaacaagtt tatagtcaag ataagaatct ttctttccat
     9781 taaataaacg ttctgataaa cgtctaccag ctgcgattgc aacaggagtc agatctaatt
     9841 taccgatcac atcaccaaca gcaaaaatat gttcatccgt tgtattttgg tatttatcta
     9901 ctttgataaa cccttttttg tccaattcca catttgtatt ttccagacct aatttttcgg
     9961 tattcggtac acgtccaccg gcaaaaagta cacaatcacc agttaaggtt tcaccatttt
    10021 caaatagcac cgtatattcg tcattgtttt tagtaatttc tttagcaata tgatgtgcgt
    10081 aagtttttat tccagcttct tggtacattt ggatcaaatt gtccgaaagc attttatcaa
    10141 acgttctaag tggtcgttct tttcgatatg cccacatgac ttcactacct aaaccacgaa
    10201 atacacctga aagttcagcc gcaatgtatc cagcacctaa aacgattgct ctcttaggta
    10261 actctgttaa ttcaaaaaat ccatttgaat caattgcgta ttctccacca ggaatggtca
    10321 ttttacttgc acggcctcca gtagcgatca agattttagg agcacgatag gtttcaccgt
    10381 ttacttcgat cgtttgacta tcgataaaag tagcgtaacc ttttatagcc tcgacatgat
    10441 tgctatctaa tcctctttga taagcaccgt gtagaaaatc aatatatttt tctcgtcttt
    10501 ctactagacc ggcgaaatca acatttttta aatctgcttg gataccgtaa cttgaggcat
    10561 ctcgttcaat tgtttccaaa atcgtacttg cttgccacat aactttttta ggtacacaac
    10621 cgacgttgac acatgttccg cccaattcat tcgcttcaat cagcaaaact tttgcgccat
    10681 gcatccctgc tctgtttgct gaagcaatac cgccagagcc gccaccaatt acgatgtaat
    10741 catatatttg cattttgttc ctccttattg aagagatcaa tcaaaacctt tatttaacga
    10801 tcctttttct acagaaaaca agtgtaacac ttttcttgaa ttttgtatgc gaagatgctt
    10861 aaaacaggga tatatcagct ttttccttat ttacgttttc ggatcatatc tccaggtttc
    10921 accggctgtg cgactggcat agttaaaatc atcattggat ttggtgctcg gtcaatggat
    10981 tcgccttctt cattatgcat aacttcaacg gtttgactga aatgactgaa tcctggacca
    11041 taaaattcga tttcatctcc tacagaaaac aagtttctct gacgtatcgt agcaatctgt
    11101 gttgcctcat cataagataa tacttcaccg acaaatttat atactgggat tttacgacgt
    11161 tcaccgaata attgttcgtt ttcagttggt gtattgtagt aaaaacctgt agctaattct
    11221 cgttgtgcta ctttccataa ctcgtcgatc cattcttgct tgcagacata gttttcagga
    11281 tcttccatat aactgtctac agccgcttta tagacatttg acaccgtaga tacataatgg
    11341 atcgatttca ttcttccttc gatcttgaag ctgtctacgc cgttttcaat caattctgga
    11401 atatgttcga tcattgacat atccactgca ctcatcgaga attcttcttc cacttcgcct
    11461 gtatcagtta aactgtttcg ttcttgacca aaaggcatat cgaacaatcc atacttccag
    11521 cgacaagatt gagaacatcc gccacggttt gcatcccgca tcgacatatg gttggacaat
    11581 gtgcatcgac cagaataaga gatacacatg gcaccatgga taaatgcttc gatttcggta
    11641 tccgtatttt tacgaatctc tgccacttcc tccattgaaa cttcacgagc taaaacgaca
    11701 cgttccaacc cttcttcttt ccagaattcc aatgtctcaa aattagttgc tgaagcttga
    11761 gtggataaat ggatcggcag acctggggct tctgtcgcac aaatttcgat caaagctgga
    11821 tcagaaacaa tcactgcaga aataccgaca tcacgcaaac tgcggaaaaa ttcccctgct
    11881 ccatcttcat ttccttcatg ggtgaccata ttagcagcaa cgtatacctt cgcatcatgt
    11941 tcttttgcaa aagcaactcc ttcagccatt tcttcataag taaaattacc tgcacggctt
    12001 cttaaaccat atgcattccc gccaatatat actgcatctg ctccataatg gatcgcggtt
    12061 tttaactttt ccagtgttcc tgctggcgct aggatttctg gtcgtttcaa ttttcttttt
    12121 actgtcattt ctttcatcat actccttatt tgatagcaga aggatcaata taaaagaatc
    12181 ctgtatctaa ttcacggttt tcaggatgca atttactgat ttcgctagtc attttttccg
    12241 ctttttcttg atcccagcta ccttctaaaa tttgtttttt tgcttcggcg aatagtcgag
    12301 tgatgtttac gaatttttcg cctggagtaa ataatccgtc caatttccat gtacagtaat
    12361 gatgctgata aagttcattc aattcattcg agagattcag atcattgctg gcaaaaatat
    12421 gtgtgccatg actatcttca taaatagaat aatgtgtctc ttctttttta ggttccgaga
    12481 taaaaagacc tctttcacga tctttttgtt cgtcttgttt cgtatagtta tagtaattct
    12541 gtagcagtgg acgtttggat tgatggatgc atgtagcacc atacacaagg gtttctacag
    12601 gaatatcgag tttttcttcc atcgccttca tctcttcaaa aggaacttca cgagcaagta
    12661 ctgctccaac tgcgcctttt ttcgcccaga aattgatttg acgtgcgctc gttactaatg
    12721 tttcagcatc ataaatatac ggtatacgca attcaggatt ttttttcatc gtataaataa
    12781 tacctgtatc accaactgtg atcacatcta cgtttatttc ttttaaaaaa gccaaatatt
    12841 caggtacatt tttcattttt tcaggatgaa tgatcccatt tacagcaata ttcgcttttt
    12901 taccatactt gtgtgctaat tctaccaatt gtcgctgttc ttctcgtgta aatgaagcag
    12961 gcagacgcaa tccaaattgc tcttcaccga aatatagtgt atctgcacct gcagcaagca
    13021 actgttctgc ttgttcaata gtttctactg tggttatgag ttcgatcata attttctcct
    13081 cctacaactt cataatagta gcatagctct aaaaactttc caatacttct tctatttaaa
    13141 gtcggatttt tgaaaattat ttcacaaaaa atcaaaataa agttcgatat attctgtcca
    13201 aatataaaaa gagattgtga caaaaatctt gtcacaacct cttaatcaag tcttactatt
    13261 ataaaaattc agctacacag gccaagtaac tatagggaac ctactgtttc ctttttaggt
    13321 ccgcgaacat tcaatgtgat cttacctttt gaagcaccta ctgttacgtg gtcacctaaa
    13381 cgaatttctc cgccaagcaa agcctcgctc aatcgatctt caatttcttt ttgaagtgcg
    13441 cgacggattg gacgtgcacc atattcagga tcaaatccag ctttcccgat cacatcgatt
    13501 gcagatggtg tgattttcac ttgaatatct tgttctttca atcgtttgat aatcgctttg
    13561 ctcatgattt ggacgattgt atggatttca tctttactca atgaatggaa gacgacagtc
    13621 tcatcgattc gattcaagaa ttcaggtcgg aaagctttct ttaactcttc taagatacgt
    13681 ttttgcatgg ctttgtgatc tttagtaaca tcttggacat tgaatccgac atttttttct
    13741 tctcgaattt gtgtcgctcc gatatttgaa gtcataatca tgattgtatt tctaaagtcc
    13801 acttttctac ctttagaatc tgttaaatga ccatcatcca atacttgcag aagtaaattg
    13861 aaaacgtctg gatgtgcttt ctccacttca tctaagagaa tcactgaata tggtttttga
    13921 cgaatttttt ctgtcaactg tccaccttca tcatacccta cgtatcctgg aggagacccg
    13981 attaatcggc ttgtactgta tttttccata aattctgaca tatcaacacg gatcagggca
    14041 tcttcacttc caaacatgac ttctgaaagt gctttggcca attctgtttt tccgacacca
    14101 gttggtccaa ggaacatgaa tgaaccaatt ggacgatcag gatctttcaa tccgcttcgt
    14161 gcacggcgga tcgcacgtga aactgctttg acagcctcat cttgaccaac gacacgttca
    14221 tgcagaagtc cttccagttc taacaagcgt tcgctttctt ttttctccaa ctgctgtaga
    14281 gggacaccag tccactccga tacaactgta gcaacatctt cttctgttac acgatcagaa
    14341 taaccttgct cctgttttgc ttcaattgca gaaacttttt gcagcttttt acgtagtgct
    14401 ttttcttgtc tgcgtaattg agcagcattt tcaaagtctt gtttttggat cgctgcttcc
    14461 ttttcttgta ctagttcatc gatttctagt ttgatcacag ttgattttgt taagtgatcg
    14521 gtttgatcca aacggacttt cgctgctgat tcatcgatca aatcaattgc tttatcgggt
    14581 agttgacgag aagtgatata acgaacagaa agattgactg ctgctcgtac agcttcatct
    14641 gtgatctcca ctccatggtg ctcttcatat cttgtacgta atccttgaag aatcacttct
    14701 gcttcttcag gagttggctc atctacttga atgcgagcaa aacgtcgctc taatgcagaa
    14761 tctttttcga tatatttttg atattcatct agggtcgttg ctccgatcgt ttgtaattct
    14821 cctcgagcta acgccggttt caagatattc gaagcatcaa ttgctccttc tgctccacct
    14881 gcaccaatta aggtatgcaa ttcatcaatg aataagatta cttgaccatc attatagatt
    14941 tcgtcgatga cctttttcat tcgatcttca aattcaccgc gatatttcgt accagcaacc
    15001 aaagatccca tatcaagcat catcaggcgc ttttcttgca tgtcttctgg cacttcacct
    15061 aaaatgattt tttgagctaa cccttcagca atggctgttt tgcctacacc aggttcaccc
    15121 accagtacag ggttattctt tgtccgtcgg ctaagaatct ggataagccg tttcacttct
    15181 ctcgaacgac caacaactgg gtccagcttg ttttcttttg ctaatttcgt caaatcacgt
    15241 gctaatgaat ctagcgtagg tgttccttgc ggtgtttgcc gtttatcttg tacatttaca
    15301 tttctacgac gattcattcc ttttccagca gaatcaccag ctagccccat tttttgtttc
    15361 agaacttgac gggcttttga aaggctgata cctaagttga tcatgattcg agtagccatg
    15421 atactttcat cttttaataa gctcatcaaa atatgttctg ttccaacttt ttgagaacca
    15481 gttttcttca cttcgctgct agctaaagca aaaacttgtt tcattcttgg tgaatatgga
    15541 agaaagactc ctttagggta agaacggata ccaccataac caatcagatg ttcaatttct
    15601 tcataaattt ccgtttcatt caaatccatt tcacgtaata cttttccagc aattccattt
    15661 tgctcgacca ctaaggctag taaaacatgt tctgaactaa ctgattgatg tttcaaccgt
    15721 tttgcttctt cttgtgcaat ttctaatact gcttgggctc tttcagtaaa aagttcttcc
    15781 atctaatctc acttcccatc ttcataactt aaacgttcca gaaatgctcg gagaatccga
    15841 gcacgtgtat gatcttcata ttcattgaaa ttcaatgtgt tttttgcaat tgcactcaac
    15901 atcaagtttc cttctttttt tgtaattatt tggtcttcat aaagtttttg aataatagca
    15961 aaagcatttt tctcactgat tgtatcatca aataactgat ttatctgctc aagtaattgt
    16021 tttttatctg aaatccttac ttttgcaatt cgtatataac caccaccacc acgtttgctt
    16081 tctactagat aaccacgttg gatggtaaaa cgggtattaa tcacatagtt gatttgtgaa
    16141 ggaacacagt taaagaggtc tgccatttca atccttcgaa tctcgatcat ttcactattt
    16201 tccagaattt tctttatata tgattcaatt aaatccgagg tattctgatg tgccatctta
    16261 ttcattccct ttgactaata ttgaccttaa ttataacgaa tttgataata gaaagaaaga
    16321 agaacgcttt ttgttaaata aatcctttag aatcaacaaa aaaaaatacg gaatatacta
    16381 ttccgtatcg acgcgcccaa gaggagtcga acccctaacc ttttgatccg tagtcaaaca
    16441 ctctatccag ttgagctatg ggcgcatatt caatttaaaa aaattataaa tcatttgaaa
    16501 acaaaaagca agataaaaaa aatcgggaag acaggattcg aacctgcgac cccttggtcc
    16561 caaaccaagt gctctaccaa gctgagctac ttcccgttta aaaaataaaa aagactacgc
    16621 gcccaagagg agtcgaaccc ctaacctttt gatccgtagt caaacactct atccagttga
    16681 gctatgggcg catatttgaa atgccgagga ccggaatcga accggtacgg tgatcactca
    16741 ccgcaggatt ttaagtcctg tgcgtctgcc agttccgcca ccccggcgcg attgctttgg
    16801 caaagcggaa aacggggttc gaacccgcga cccccacctt ggcaaggtgg tgctctacca
    16861 ctgagctatt tccgcgtgtt taaagatgcc ggctaaagga cttgaaccct cgaccctctg
    16921 attacaaatc agatgctcta ccaactgagc taagccggca tgtaaaactt aaattatgcg
    16981 ggtgaaggga cttgaacccc cacgccgtaa ggcgctagat cctaaatcta gtgcgtctgc
    17041 caattccgcc acacccgcaa aaatatgagc cgtacagggc tcgaacctgt gaccctctga
    17101 ttaaaagtca gatgctctac caactgagct aacggctcat atggaggtta acgggatcga
    17161 accgctgacc ctctgcttgt aaggcagatg ctctcccagc tgagctaaac ctccatggat
    17221 aacttaagcg tggcgacgtc ctactctcac aaggggcaac ccctcactac aatcggcgct
    17281 aagaagctta acttctgtgt tcggcatggt tacaggtgta tccttctcgc tatcgccacc
    17341 acactgtggt gttatctttt attgagtaaa ttttgttcac tcaaaactgg atttgaagtc
    17401 acataagttt ttttccgagt tcttttcttt taacctattg gttaagtcct cgatcgatta
    17461 gtatcagtcc gctccataca tcactgtact tccactcctg acctatctac ctgatcatct
    17521 ctcagg
//
LOCUS       DAPBAF010000053        16591 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.053, whole genome shotgun sequence.
ACCESSION   DAPBAF010000053 DAPBAF010000000
VERSION     DAPBAF010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16591)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16591)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16591
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.053"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(81..788)
                     /locus_tag="RD451_002308"
     CDS             complement(81..788)
                     /locus_tag="RD451_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HDT7567524.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
     gene            complement(867..1205)
                     /locus_tag="RD451_002309"
     CDS             complement(867..1205)
                     /locus_tag="RD451_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HDT7567525.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            complement(1316..2278)
                     /locus_tag="RD451_002310"
     CDS             complement(1316..2278)
                     /locus_tag="RD451_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HDT7567526.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            complement(2293..3624)
                     /locus_tag="RD451_002311"
     CDS             complement(2293..3624)
                     /locus_tag="RD451_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HDT7567527.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            complement(3632..4312)
                     /locus_tag="RD451_002312"
     CDS             complement(3632..4312)
                     /locus_tag="RD451_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HDT7567528.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            complement(4531..5010)
                     /locus_tag="RD451_002313"
     CDS             complement(4531..5010)
                     /locus_tag="RD451_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HDT7567529.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            complement(5137..6816)
                     /locus_tag="RD451_002314"
     CDS             complement(5137..6816)
                     /locus_tag="RD451_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HDT7567530.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            7364..8866
                     /locus_tag="RD451_002315"
     CDS             7364..8866
                     /locus_tag="RD451_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7567531.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESRETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            8879..9541
                     /locus_tag="RD451_002316"
     CDS             8879..9541
                     /locus_tag="RD451_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7567532.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(9642..9845)
                     /locus_tag="RD451_002317"
     CDS             complement(9642..9845)
                     /locus_tag="RD451_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HDT7567533.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(9956..11140)
                     /gene="iadA"
                     /locus_tag="RD451_002318"
     CDS             complement(9956..11140)
                     /gene="iadA"
                     /locus_tag="RD451_002318"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HDT7567534.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            complement(11297..13036)
                     /gene="yfcC"
                     /locus_tag="RD451_002319"
     CDS             complement(11297..13036)
                     /gene="yfcC"
                     /locus_tag="RD451_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HDT7567535.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVAPQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            complement(13809..14423)
                     /locus_tag="RD451_002320"
     CDS             complement(13809..14423)
                     /locus_tag="RD451_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDT7567536.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
     gene            complement(15029..15406)
                     /locus_tag="RD451_002321"
     CDS             complement(15029..15406)
                     /locus_tag="RD451_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567537.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            complement(15706..16587)
                     /gene="galU"
                     /locus_tag="RD451_002322"
     CDS             complement(15706..16587)
                     /gene="galU"
                     /locus_tag="RD451_002322"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HDT7567538.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
BASE COUNT         4808 a         3573 c         2834 g         5376 t
ORIGIN      
        1 tattccaaat aaatggtatt caatcagcta actctcggta ttagctcaga tcaaagcgct
       61 gatttcacaa cttctttatt ttaatctctt cggttgccgc cgaacaataa gatcaagcgc
      121 aacagctgca ggaatgtcga aagcgctgct gcaacataag tcagtgctgc tgcaaataat
      181 acgtgtcttg ccatcggtac ttcttcttcc gtcagtagtc cgccttcact caaaatttgg
      241 attgctcgcc gagacgcgtt aaattcgact ggtaatgtca ccaattggaa aagtaatgct
      301 aaagaaaaag cgaaaatccc gatattgatt aacgtagagt tccagctaag caatacacct
      361 accataatca aggggaacga aatcatcgaa ccaaagttag ctgctggaac aagtgctgca
      421 cgaatcttca atgggacata acccgaagca tcttgtaccg catgtccgca ttcatgagct
      481 gctacaccta tcgcagcaac tgaagtagac tgtgcagttg cttgagacaa actcaacatc
      541 ttattacctg aattgtagtt atctgtgaga tctccggcaa tttgttgaac accgacatta
      601 tttatctgtt gactttgtaa tatatattgt gctgcttgtg taccagtcac attgtttttg
      661 cttctcactt gatcgtattt tcggaaagta ctattgacgt acgctgacgc aattccggaa
      721 ataactaatc caagaatgac caaaagaaat gtcggatcta aaaaaccata cattccataa
      781 ccatacattt tcgtttcact ccttttcgtt tactttattt tatcattagt agtaggaaaa
      841 gaatgtgaaa agaccttgaa tattctttaa ttctttttca caaattccga tttcagtttc
      901 atcggtccaa atccttctac cttgcaatcg atattatgat cgccttctac taaacggatg
      961 ttcttgactt ttgttccttg tttaatggca cctgacgcac cttttacttt caagtcttta
     1021 atcactgtca cgctatcgcc ctctaacaga cggtttccat ttgcatctaa taccactaat
     1081 ccgtcttcta tgacagtttc ttgttcttct ttgttccatt cgttcccgca ttctgggcaa
     1141 atcaacaagc ctcgatcttc atatgtgtac tctgagccac attctgggca atttggtaat
     1201 gtcatcttct ttctccttta aaatctttag tgagcactat tgtaacggaa aaagaagatc
     1261 ttgaaaagat acatttgtga tttttactac aaaaggcacg ttttcgaacg aagtatcatt
     1321 ctgtttttct gctcttatac gattggcata tatcttggat ctctttatag atttcctcta
     1381 cttctgctaa atcttttgca ttcgcaccac ttgctaatgg atggcctcct ccatgatggc
     1441 gtttagccaa ttcattgatg atcggcccct tagaacgtaa acgtacgcgg taataccctg
     1501 aaggctgctg aacaaaaatc ccccaagcca gcacttcgtc aatcactcca ggaagtgaaa
     1561 cgatcgaagc tgtctctgaa tcatcgattc catatttatc aagaatttct tgcggaagga
     1621 ttattcttcc tgcaccattt tcatccacct ggatattttg ataaagataa ccggaaagtt
     1681 tagcgacttt catcggcatt tgttcaatct ctctgttcaa agcacttgca tcaaatggat
     1741 aatttctcaa tatcgaagca atctctaatg tacgggacgt cgtggaggga tacaaaaagc
     1801 gccctgtatc tccgacgatt cctgcataaa gtaaccgtgc agccttaacg ttcatcttta
     1861 aagattcagg aaacatcaaa gcaaattctg caatcatctc actacagcta cttgcttttg
     1921 tatttaccca cacaagatct ccataagggt catcattggg atgatggtcg attttgatca
     1981 gtttttctgc caactgatat ctttgatcac tgattctggg tgaattagct gtatcagtca
     2041 cgatgactag cgctccttgg tagaagacat cttcaacttc ttgcatttct gctaaaaagc
     2101 gaagcccttc aatcgtttca cctacttgac gtatttcttt ttctgggaaa ctttcccgta
     2161 atagttcggc taatcctact tgtgatccta atgcatcagg atcagggcgc aaatgcctgt
     2221 ggataatgat tttatcgtat ttttttattg tatctactat ttcttgctgt actgtcattt
     2281 cactcctgct ttctaagaac gttccattac ttgacaaaca acgattgctt tggaaacgat
     2341 ggtgttttca ataaacactt cgatatccag tttagcggaa cgtctgccga tttccaatac
     2401 acgtggacga atgtctaatt cgctttccaa ttggatcagc cgcaaataat gtaggttcac
     2461 ttgttcaatc aagatatttc gtttttggtt catcaccatt gttttttgtg cgacatcaga
     2521 aatgatttcg ctaagtacgc caaaagaaat ggttccaacg ccattgacca tttgtggtgc
     2581 tactacgaat ttgaacttag ggttttccaa acgatttcct tcacggtcag tatcaatcgt
     2641 atggatattt ccagatatct gatccgaaat cgtatctgca atctgcggtt gtcgctggac
     2701 aagctgcatc gctttcatta catcttgccg ggtaatcaag ccttccaatg tcaagtcatc
     2761 ggaaacgacc ggcatgactt ctagcccatc ccagatcatt tgatggctaa cagaggcaat
     2821 actcattgtt ttctttacac tgattggttc tttcgtcatc acccgatcga tgatctggtt
     2881 tggcgatttc cctaaaacat cttttgccgt aacaatcccc atcaaacgat gatggcggtt
     2941 gacgactgga aaacgcgaat gctgcgtttc ttctgacaaa cgctgataat cagaaatcgt
     3001 atctgtctgc tgcaaataat gagtcttttc agctggcata tagatatcac tgacaagcat
     3061 gatatctttt ttgatcaatt ggtcgcttaa cgctcggttg atcatggttg cgactgtaaa
     3121 tgtatcataa gaggtgcgta agatcggcat ttcaagatca tcagctagct ttgcaatctc
     3181 agcagtcgta ttgaatcctc ctgtgatcaa tactgcggcg ccatcttcca atgctaattt
     3241 ttggacttcc gcccggttgc cgacgatcat tagtgatcct ggcgtaatat agcgttccat
     3301 ggcatgttta gtcatcgcgc cgatgacgaa tttattcaag accttgtcta atcctgccgc
     3361 cccgcctaaa acgtcccctt caatgatcct gacgacctcg ccaaatgtca aacgttcaat
     3421 atgttttttt aatttgcgtt cgatacggat ggtccctact cgttgaattg ttgaaactag
     3481 tccgacattt tctgcatctt tgattgcacg gtacgctgtt ccttcactga cattcaattc
     3541 ttttgcgatg cttcttacag aaattcgatt gccaacaggt aaactttcaa tatattctaa
     3601 aatcaaatca tgttttgtcg ccattttctg cctacacttc cagcgtttcc gagacgctca
     3661 ttatttttcc ttcactatct tccagtaact ctacaaaaga ttcgggatct tgttcaatga
     3721 cagggaaagt attgtaatgg attggaacta ctttcttggc acgaattgtt tgcgcagcct
     3781 ttgctgcatc ttctggcccc atcgtatagt tatcgccaat cggcaagaaa gcgacatcaa
     3841 tatcgaattc ttctgcaagc aatcctagat cactgaaata agcagtatcc cctgcatgat
     3901 aaatcgtttt tccttctgct tgaataataa ttccgctagg ctcgcccata tactgaacga
     3961 taccgtctac ttcatagctt gaactatgct gtgcatgtac gaattttacc acgccgaatg
     4021 gaaacgcatg ttttccaccg atattcatac cgaatgaatc tactcctctg ctgttcgcat
     4081 aatcagcaat ctcaacaata ctgataattg tggcttgatt ttcttttgca ataggaatca
     4141 tatctcctat gtggtcacta tgaccatgag taatcagcaa ccaatctgtc tttacttctt
     4201 ctgcagttaa gtctgtcaat ggatttcctg taataaacgg gtcaatcatc acgcgttggc
     4261 cattttccat ttcaattgtt aaacaggaat gtccatgata cgtaattttc atattttaca
     4321 cctcgcgttt tctctgtatc ttttttatta aaaacgattt catcacttgc acatcaatga
     4381 aaaaatatag ctgctaaata tattttcatt ggattgatag tacagtatgt acaaagcaat
     4441 tgtaacagat aatacaggat gcaccaagta ccaagcagat ataatctcaa gtttgaggtc
     4501 tctgctctgc ttagcttctc ttctcgtccc ttaactaatt aaatcagcgt aaataggatg
     4561 gacgatcttt tctaaatcgg ctacttttat ccgaaggctt ctcccgattt caccgcttga
     4621 cacaattact tcttcttttt cttttaaaga actgtctgct aaaaaacaat aatcaggatg
     4681 tgcgagtttt attccaatag gggtgtttgc tccgtgggga tatcctgtat gcattaatac
     4741 aaaatccatt ccaggaaaac caactttacg atctttcgtc acttgtctcg tttttttgta
     4801 atctaagtga tcgttcaaag gaatcaatgc gatgatcacc ccagttttgt ttcctttcac
     4861 tacgagagtt ttacatatca aagctggatc aatccctctt ttttgtagtt cttctgtgaa
     4921 agattcttct accacatgac taaaatcaag tggttgatag ctgatctttt gttcttctaa
     4981 ataacgttcg acttttgttt gactcatcat tgattcactc cctttattct atcgtttatt
     5041 ataaagcgag ggatgctgta ttcaaaaatt atttgttttt cgcaaaaaaa gagcaagacg
     5101 agcactctat agagaggttc atcttactct ttttgtttat tttttatttc gacgttgagt
     5161 agcttccata atgactggca agatcactgg gcggcgtttt gtttgttcaa ataagtaacg
     5221 gcctaattga tctcggatgt cttgctttaa tttgctccac tcaaaatcat tgctttctaa
     5281 atgtttctca acgattgttt caatcatatt gctgctttct ttcatcagat cacggctagc
     5341 ttttacgtaa acgaatcccc gtgaagtaat ttgaggtttt gaaatgattt tcttttctcg
     5401 ccgactgata gtgacaaccg ctacgaaaat cccgtcttct gacaagattt ttcgatcacg
     5461 taaaacaatg tttccgatat cacctatgcc taatccatca atcattacat tttctgcact
     5521 tgtagttcct gcaacactca tacgcttgtt cttatattcc agcacgtctc cgcgtccagt
     5581 aatatagata tttttgtatg gcatccctac tgcatgagcc aaatctgcat gagcagctaa
     5641 ttcacgatac tctccttgaa ctggcacaaa atatgttggt ttcatcaaat tgatcattaa
     5701 ttgcaagtca ttaggattgg catggccaga aacgcgcata ttctcagaga tcaacttcac
     5761 tgttccacca gctcgataaa tgatatcttc cgttttcgcc acgatggttt ccatcgcgat
     5821 gcttggcgta gtagtgatat aaaccaaatc tccttcttca atcttgacat tacggtgtgt
     5881 accgtttgcc attttttgca gagacttgat gggttcaccc attcggccag tttctaaaat
     5941 gatcagttct tctggatcat agtttttcat gtctttcaac gtaacaagca gatcttcact
     6001 tggtaattga agtttttcta aacgcatcgc tgtgcgaata attcgttcga aatcttgacc
     6061 agtcaagaca acttttcgtt gtgctttttc tgctgcatcc aatacttgtt gcactcgttg
     6121 caaattactt gctacacaag cgacgatgat acgcccttcc caatatttga tcgtatcaaa
     6181 tacttcatct gctatttggg cttcagaagc tacaggctga ggattttctg catttgccga
     6241 ttcacttagt aaggctaaga ctccttcttt gccgatttcc gccaatcgtg cataatctgt
     6301 ttgatacatt gggatagccg tttggtcaaa tttaaaatct cccgtataaa cgatactacc
     6361 ttcttttgtt ttcagattga tccccactga atctggtatc gtatgagtgg tacggaaaaa
     6421 gctcactact gtttcaccaa agtctatttc tgtatgctca tctaccacat ggaaatcctt
     6481 aaatcctttg gctgcttcat tacgactgac attcaatttt gctaactcga tcgtcaactc
     6541 tgtcccgaat actggtacag aaatttttga caacaagtaa ggaagtgccc cgatcgcatc
     6601 tgcatgtcca tgtgttaaaa agacaccagc tacacgatca atgttttctt ctaaatacgt
     6661 aaaatcaggg attacgacgt cgatccccaa caactcattt tcaggatatt ttagcccaca
     6721 atctaaaata aaaatatcct cgcccacttc tgcgacatac atgttttttc cattttcacg
     6781 aacgccgcct aatgggataa ttttaatggt actcacaaac ttcacctctt cttatgacat
     6841 ccaagtttaa agatgtcgat tttcttcttt atctaaatat atgagccatt ccaatgaagc
     6901 atatgcaaaa tcactatttc tcaacttatg gagaatcagc aggaaaatta ccagcacatc
     6961 cgcgttctga cagttggatg ggcattttat tttggatata cttcattaac aaaatggatc
     7021 ttttgcgaaa cgctatagcc agaatactta tataagtatt cagctgttcc ccattattat
     7081 acaacaaata aactaaatcg ctagtatcag caattgttag aacaactatg cacgtaaaaa
     7141 tccctctgta gcatctagga tttcttttgc tattcctctt tcatttcttc ttcgtcggtt
     7201 tgaaacatac ttttttcatt ttaccacatt ttttgcaata actatagtga ctttttatat
     7261 atacagaacc tcatgttgat ggtgtgcaaa cagcataaga tttaagctag ctttaagata
     7321 ggttgtctat tatcaaatgc atctactagg agggatgcaa aatatgaatt ttatgaaacg
     7381 tgcatggaaa agtacaaaag taaaatgggg acgttcattg ttattgtttg ccgtgttcac
     7441 agccattctt atttttgtgc tagctggcct cacgattcga agcgctgcag aagaagcagc
     7501 gaatcaagca caaaaagaag ttggagcaac agtgacttta agtgccaatc gagaagcttc
     7561 atttaaaaaa caggaacaaa cttcttcaag cggttctacc actgaagaac gtccagatcc
     7621 aggcagtttt tctcttacac cagtttcctt aacggacgcg gaaaaaatag ctgaattaga
     7681 taatgtaaag agttattcct ttgaaagttc cgcctcagct atggcaaaag atggaataac
     7741 tgccatcact agttctgatt caagtgaaga cagttcagaa actactgatg caggcggtga
     7801 acctgctgga ggaatgggcg ggaatccgca aatgactcaa gcagactttc aaatcagtgg
     7861 tgtgtcagca actgcacaaa atagtaattt ttctgatgga acagcaaaaa tcacggatgg
     7921 tgaaggaata gatgacagcg acaaaggcac aaacaatgta gtcattgatt ctactctagc
     7981 agaaacaaat gacctggcag tcggagatac tttcacaatc acgagtactg aagatgaaga
     8041 taccacttat gaaatgacga tcaaaggaat ttatgaatcc agagaaacaa gcggcagtat
     8101 gggtatgaaa ttcaacttca tgaatccgtc gaatacactt tacacttctt acacttttgc
     8161 aaatgaacta aatgggacat ctgacgataa cacgatagat tctgctattt acactctatc
     8221 tgatccagat aaaatggatg agtttctcaa agaagctgag aagctgatcg acacagatac
     8281 atttagctta caatcaaatg attccatgta tcagtcaatg ttggaacctt taaacaacgt
     8341 ggcaagtttt tctaaaaatg ttgttttact agtggctgta gccggtatta tcatacttac
     8401 tctgatcatt atgattacca ttcgggagcg tcggcatgag ttaggcgtct tgctatcttt
     8461 aggagaatcc agaagtaaaa tcattctcca attgtttacc gaagtggcta tttgtatgat
     8521 tcttgcatta ggagttgctt cgcttagcgg aaacgtcgtc gcgaatgccg tgggacagca
     8581 gctacttgac caacagacag aaaccacgac acaaaaccag caagctcctg gcggtggaca
     8641 aatgccaggt aacagacaag aacaaggcgg tcaacgcgat ggtcaacaag gaaccacgaa
     8701 taatccattt gctgtttctg atcaagtcag cgaattggaa atcaatgtca aacctgcaca
     8761 attgggacta ttagccggag tagcatttgg aatcagtctg ttttctgtct ttttagcttc
     8821 tatagggata ttaagattaa acccaagaaa aatcctatta aactaaagga ggaatttgat
     8881 gttacggaca gaacaattgg gattttggta tcaagatccg caagatgcgc tttataaaga
     8941 tgtagaactg aatttcgaag ctggaaaaat gtacgctatt ttaggagcaa gtggttctgg
     9001 aaaaacgact tttctttcgc ttatttctgg actagatgca ccaaaagaag gaaaggtata
     9061 ctatcaagat cgttcactga acaaaatcgg gttaagaagt tatcgtaaaa atgatgtctc
     9121 gattattttc caagcttaca acttgcttcc ttatttatcg gctctagaca acgtcatagc
     9181 agcaatggaa atcactaaga ccaagcaaga gaattatcga caagttgctt tagatcgact
     9241 ggctcgtgta ggaattgatg aaatattagc aaaaaaacag gtgaccaaac tttcgggagg
     9301 tcagcagcag cgagtcgcta tcgttcgtgc tatctgctgt gaacatcaac taatcgtagc
     9361 ggatgagcct actggaaatc tagatgaaac aacttcacaa gatatcgtca aacttttcca
     9421 agaaatcgcc catgaacaaa atcgctgtat tatcatcgtg actcatgaga ttgaagtagc
     9481 aaaaagctgt gatgaagtct ttgaactaaa aaataaaaaa tttcaaaaaa tcgaagttta
     9541 aaaaacagga taatgatcaa ataaaaaatc cgaaccatat ctgtctcgca gatatggttc
     9601 ggatttttta tttgcttgat tcaattagta ataagtggtt tttatttttt ttcgtctttt
     9661 cgagaaaact tgtctttgac ttcgtcgcct aaatttcgag ctttttcttt gatgtcagca
     9721 cctagtgatt gtgctttccc ttctgtttct ttgctcttgt cgtctgttgc tttgccgtat
     9781 gcttcttttc cttcaccgac tactttatct ttcatatctt tagaacgtcc ttttaaatct
     9841 gccattgtgc ttcctcctct tagtttgttt attgatctac cttcagggta acatcaacaa
     9901 cagatacaga caaacagaac gctcgttttc taaaaaagat agttagagct gttgattaaa
     9961 aacttttttc gaaagtcccc catactttga cttctttttc ttggaccatt atttctcctt
    10021 tagcgataac tgtatcaata tcaagcgttt ctttatccaa gatacacaga tctgcatcag
    10081 caccaatttc gatttttcct tttttatcca atttcaatat acgtgctgga ttactggtta
    10141 tagctcgtaa ggcgatttcc aaagggatac tttctttttg cacagcttct ttgatcccta
    10201 ctagcaatgc cttggcactt cctactccta accctaggaa atgattgttt tcatcaaaat
    10261 aaggcaagct tccttgtcca tctgaggtca tcgtgaaatt atctaaagaa acatcttcct
    10321 cgatcaatcg tttcagtgct ttgctgaagc gaacttcacc atctgtcttc tcccaaaaat
    10381 caggatcttc gctagcagtg aagtcaatcg tgccaccacg tttggcaaat gccacgcaag
    10441 cttcaaataa ttctggtgtg cgatttgcat gagtaggcaa aaattgtgtg atcggaattt
    10501 ctgtttcttc tacgattcgt gtcaatagct ctagctttct ttttcctccg cctaagtgga
    10561 cattgatgat cccagctttt ccggataaca tgcctcctac acgagcatct gctactgcac
    10621 gagcgaactc ttcaaaactt ggctgagaag aacggtgatc ggatactgcg atttctccga
    10681 ttccgataat tttatcaatt gtcaaaaagt ctttgatgat agaatctgtt actgttttta
    10741 ccggcaatcg gtacgaacct tcgtatacat aagtggagat tccttctgct tccagacctt
    10801 tcgctttgct gatcaacgca gtcatatctc taccttctcc gtctgttccc aaacaaccga
    10861 caactgtcgt tacaccagct gtagtcaatt ggctcaatgt gacttctggc gttcgatttt
    10921 gataaccgcc ttctcctcct ccacctaaaa tatggaaatg acagtcaatg aaacccgggg
    10981 ttagtacttt tccctcacct gaaagttctt ctacttccac tccttcgtag ccgccttcta
    11041 gctgttcttc tacagccaaa atcttcccac cggcaatcag tacatccatt tttcctaagt
    11101 aatctggtgc aaacacttca atttgtcgaa tgattttcat acatttttcc tctttcttta
    11161 agtataactg atgataggat cttaaaaaat aatccaaacg ataggatctt tactcctttg
    11221 attttaccgt aaaatgacgg ttcttggagt ccttatctac tgtttggatt acttttttat
    11281 ttacaggtct ccagtactac tgcagaccta ttgcaatggc aatcatgatg aaaatagttc
    11341 ctaaaacaaa caggaatcct tgcatcttga tttggaatct tgcccatttt gcccattcga
    11401 tccgtgcaac acctagcaca ccaatcaagc tggctgatac gggtgtaaaa gcgtccataa
    11461 aacctgaacc aagctgataa gcaagaactg ctacttgtct ggatacacct actaaatctg
    11521 ccagtggagc catgattggc atagtcaaag ctgcttgtcc tgaatttgat gtaacaacca
    11581 agttgaacaa actttggaag atgtacatcg cccaagcacc aatgacagct ggaacaccgg
    11641 tcaacgccgt cccgatccca tgcaaaatcg tattcaaagc tgaaggaaca gatgcatcag
    11701 atcctcccaa gacaagaaga atccctttgg ccatacctac tacgattgct gtaccagcta
    11761 aatcagctgc accagattgg aaagaagaag cgatgtcatt gactttcatt ccatctaatt
    11821 tgaaaagaac agcaatgatt ccagcaacta atcccatcac aaagaattga gaagcgattt
    11881 ctggaatgta atagcctttt tgagtcacgc cccaaacgat ccagacaagg acaactaaca
    11941 tctctaataa gatcaattta tgcccaagca tgaatttttt attttcatca gatgtctttt
    12001 tgatatgaga acggaaataa tcatctgatt tgtaagtcaa cgaactttct ggttttttac
    12061 ggattttttc tgcatatatc atcatataac cagcggctaa tgcagtaaca actacccaca
    12121 taatcaatcg gaatgtcgca ccagacaaca cggggattcc agcaatccct tgagccaccg
    12181 ctacgctaaa cgggctcatc caagaggtcg catttccgac ttgaggtgcg acataagtca
    12241 cggttactgc tacgatcgag tcatatccta acgcaatgac aaatggaacc atcaccattg
    12301 agaatggaat tacctcttct gccatcccga atgtagcgcc accgaatgaa aaagcaaaga
    12361 ataatagcgg taaagctaaa cgctccagtc ccttagtttt actgataaac gcatagatac
    12421 ctgcgtcgat cgctccggta cgcataataa taccaaaagc acctccaaca acaaggatca
    12481 atgcagcgat ccctacagca gatccatact tatctccaga tactagtcct tcaaaaacaa
    12541 aatttaagaa accaaagccg ccaaaatcat ctgttcccca tattttggct gttttatgca
    12601 attttttaga agtatcatag atattttcgc cgtactgatc gtaaagcaca tcatctgtca
    12661 aggagatttc atctagtttt tcctgcgtaa gatttttttc tccgtcagca atgacttttt
    12721 ccaatccttt ttccggaaca tccagttttt cacgttctgc tggatgatct tgcagttctt
    12781 ctaattgatc aaacacatac gacttatcca gctcgtaagc ataacggaag gaatcttgac
    12841 gtaaaacagt acgagtactt gtttcgccat ttgcatcttt gtattcaata tcttgcgtgc
    12901 tgaactttcc tgctggaacg acaaaagtca gtatccatgc aaagatgact acaccaaaaa
    12961 taatgacata cgtatggggt gtcgataatt tagtgaagtc gcgtttcggt tttcctgaag
    13021 aatttgtttt cttcaaattt atttcttcct ttcttttttc agtaattttg atgaataaaa
    13081 aatggataat caaatgaatt atacagtaaa aatgacattt ccacatgaat aatttattag
    13141 aaaatcactt ttttctattt tgtttttttt ctcctatgta tgattatttt tttctctttc
    13201 catttatatt aagtatttta tttctctgtt tttccttaaa attctttttt tatttttaga
    13261 ttagagaaaa tctcgtcctg tttttttcat tttacaatca ttgaaaaatt gaatttcatt
    13321 gcaaaaaaaa taataaacac ttataaatat ccattatcta tccttcaatt tttgtgtatt
    13381 ttatttctat tagaaaaagg tatcctgttg gacaattttg ttatatcagg taaacttcat
    13441 tgcaataatg ataacaaatg tactataatt actttgtaaa gagttttggg gaagactctt
    13501 tcatcaacgt gtattaagag acaagaaaga atccatatgg attctttctt gtctcttttt
    13561 ccactacttt ttatttttct gacactacat attcttataa ctcatttctc ataactgtga
    13621 aacaacttat aaaaataaca aactttaaac aaaacaagct taaaatcaaa gatgatccat
    13681 cttaaaataa ctaaaacaaa aaaagtagtc gttgttaatc ctcattaata atcgttttct
    13741 ttttttcaaa cgctccattt ttatgtggaa cattattttt ttaaggaact ttgtcaacat
    13801 gtggataact attttccact tgtgtcctgg actagctgtt ttgctgtaaa atacaaaact
    13861 tgctgcagca aaaagatcgt tgcaagagag gctgttccgc agatcgctgg atctagattt
    13921 ggcaaagtca agactgcatc atgtaaattg gcgtggttgt ccaaaaccaa atcagcaaat
    13981 tcaaataatc gcaaaccact gctatgttgc gatttgatac ttcgtgacaa atcaaatcca
    14041 gtaacaatga ttaatggatg accattttct ttgatccact gagctagttc gatgattgcc
    14101 gggtttcttc cttcattcga aagaagaaga aaaatgtctt ctgatttgac agaaagctga
    14161 tcaataattg cctgtcctgc accttctagc gtttcataga cacctccggc tggattttca
    14221 atcaatatac ttggtacaag atccggggtt tgatcccaaa attcaaatgc tacaccactt
    14281 agtgtgcggc tagcatatat ctgcaatcta ccaccttgat taatttgttt cgcgatccaa
    14341 gtgccagctt gaagcatcag cggctcttct atccttaatt tctcttccaa ttggtgataa
    14401 tagtcaaaat aacataaact catttatctc tcccgcctag ctatacttga catgaataga
    14461 aacagctgcc taatctaagg aagtacataa aaaaacagta gttagacagt aacacatgtg
    14521 gtctttgctg tttcaaacac aaaaaaggca ttgaacgaat acgcccaata ccttgacata
    14581 gcaaataaaa caacgtgcag accatggaaa atatctacat aggggtagaa ttttcaccct
    14641 agattaggta caataaatta ggtcgatgca ctgcattgac tatggcaaaa tgatcggtca
    14701 gggtgtatgt gtgtgactgg tcattccctg attcttagcg ccaactaagg gtcagggagc
    14761 ctttttttat tcagctgttt ctatctgaat ttattgtaag taatctctta tccaagtgca
    14821 agcaagaaaa tacaaaaaaa cattggtatg atttatatat atataaataa cataaaaaaa
    14881 ggaatggctt atcccgatac aacaagcatt cctttaaaaa agattctttt atataagtga
    14941 aaaaagcttt tttccaccaa ttaaataaat ctctcatctc aatagtttat ccattatttt
    15001 atcttttttt gcgtatacct actaaatatt accgtcttct tctcgttctt ctactttgtt
    15061 cgagagaatc tgtactagaa aaagtagttg tatgtctacc ttttctgcct atccgagact
    15121 ttcttttcat atatgggata taaatgatta gatacagtac agcaaaaaat aaagcaaata
    15181 cgcaagcttc ccaactacct aacgccaatt caaccatcaa ggtagcaacc ccaacggatg
    15241 ctgcatacca gataaaaatc agaaacgttt ctttttttct gaccatgcga aacatgataa
    15301 atagactaat aagcaatagt ggcaacacaa atatccaatt gcttccttcc atcagccact
    15361 tgagtatatc aagcagcgac tgtgcaacag cgactaattt tcccatagtg aacacacacc
    15421 tttttttata attaaaaaat tcgccttttt attctactat gaatcttctg gcttggcttt
    15481 catttctctt atgtaatcat tttcttttat acaacttaaa aaaaaattaa accattagca
    15541 taatattttc tgaatctatt cacgaaagtc tttttctatc tttcgttttc cacgactcaa
    15601 ctgatctaga gtcaaaaaac taaaacgaca gttgcgcaaa tgacgcacaa gctgccgctt
    15661 taataacaaa tagcctttca ttctcagcag gccacttatt tccagttaac tttctgttct
    15721 tagcttttta ctcaactgga taatatatgc acttaatgaa gtcccaattt ccgaatgttg
    15781 aagtccatat tcaatatttg tcttcatata tcctaactta tcgcctacgt cgtatctttt
    15841 tcctttaaac tctctcgcat agaccgcctc tgtctggtta agagtctgaa gtgcatccgt
    15901 tagctgtatc tcgtttcctg ctcctggttc ttgagtttct aatatctcaa atattttagg
    15961 agtcagtaga taacgtccga taatggctaa attacttggt gcttttccca tttcaggttt
    16021 ttctacaaac ccttttactc tgcaacgacc cttttcgcta tctgttttag gatcaataat
    16081 tccgtattta gatgtttcat tttctggtac acgcatgacg gcaacagcgg aagcttgtgt
    16141 ttcttcataa tccatcatca attgttgagt caatgggata tcatctttca tcaaatcatc
    16201 ccccagcatg acgacaaacg gttcatttcc tataaatgct tttgcttgaa gcacggcatc
    16261 ccccagtcct cttggatgag attgacggat gaagtgaaga ttgacttgag tcgtttcttc
    16321 aactaaagcg agtaattctg ttttttcctt ttcccgcaaa ttgttttcca attcgatatt
    16381 tgcatcaaag tgatcttcaa tgggtctttt ttcttttccc gttacgatca agatgtcttc
    16441 gattcccgaa tccaatgctt cttccacaat aaactggatc gttggtttat ccacgattgg
    16501 aagcatttct tttgccatgg cttttgttgc cggcaaaaaa cgtgttccta gcccagcggc
    16561 aggaatgact gcttttttga ccttcacttg c
//
LOCUS       DAPBAF010000054        16558 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.054, whole genome shotgun sequence.
ACCESSION   DAPBAF010000054 DAPBAF010000000
VERSION     DAPBAF010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16558)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16558)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16558
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.054"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            14..1141
                     /locus_tag="RD451_002323"
     CDS             14..1141
                     /locus_tag="RD451_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDT7567539.1"
                     /translation="MAFLFVSLNYTNGEDINDDGSRKKVEKVGGDTRPEAEAALRKVL
                     SDIDETGQYFLGTDTRVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKL
                     TDLSPALLQNFINAEFKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPK
                     YEARPTTKKDLKIISLEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVD
                     FSNGTITVEKQMVKNDGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYG
                     KLYIDSNAVCTKEDGELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKM
                     KEISERLGHSRISITMDTYSHVTDKMRNETVDIMENLRKNS"
     gene            complement(1359..2501)
                     /locus_tag="RD451_002324"
     CDS             complement(1359..2501)
                     /locus_tag="RD451_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDT7567540.1"
                     /translation="MRKIANVYKDRKRGTWFFSATLGQDRFGKRIQVTRRGFKTQGEA
                     RRGLEELKQSFSDSQGIYLQGITFHDFYREYFFPWYKLGTVEKTYMKTDHILQRALDF
                     FGEMQVVKIRPIHIQEFQQFLSKIHVVKKGIEQPLSPNYIKQIFNKLRVVFKRAIVLE
                     IIEENPVDTIGKIKTQRPQVEFWTVDEFKKVYNSVYHGDFYEEFYKRLMRFIFVTGVR
                     SEELLALQWKDFDLINGRCSVNKSIYIRTRQDYEFAETKNTSSIRIISLDRQTVEDLK
                     TWKKTQQSIGKNIELVFSFDGLPPSPRTILSRIKKLAEIAGVKPIHMHGLRHSHVAFL
                     IEHNKNIYAISKRLGHASIKTTLDKYGHLYPETNQALANEITRFDI"
     gene            complement(2506..2691)
                     /locus_tag="RD451_002325"
     CDS             complement(2506..2691)
                     /locus_tag="RD451_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HDT7567541.1"
                     /translation="MKTATRKDLINLGFSQYYANKIFKECKELLVEKGYFFYRNSKIK
                     RIPISILEEVLHISWEE"
     gene            complement(3045..3290)
                     /locus_tag="RD451_002326"
     CDS             complement(3045..3290)
                     /locus_tag="RD451_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7567542.1"
                     /translation="MVDKSKKRQYLLVPLSIILSALEGDPISIKMILKHYHSYMAKLC
                     LTNGFNEVGQFVTYVDEYMISQLEIKLIEAILKFKIN"
     gene            complement(3284..3685)
                     /locus_tag="RD451_002327"
     CDS             complement(3284..3685)
                     /locus_tag="RD451_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDT7567543.1"
                     /translation="MQQHYNDISIQHQFDAYCKKVLRNEAKSIRKRNANIKDNEEPLA
                     DSNEGRYSQTHFDEQDVYFLFGMEILISDQKLSAAIDQLSEIRRKIILLYYFAGFNDA
                     EIGKILNMSTSGIWYQRKKAVEQLKMGYDLW"
     gene            complement(3872..5680)
                     /gene="uidA"
                     /locus_tag="RD451_002328"
     CDS             complement(3872..5680)
                     /gene="uidA"
                     /locus_tag="RD451_002328"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HDT7567544.1"
                     /translation="MLYPIMTETRQVIDLSGLWRFKLDTNDDLQEELALEPINEKESY
                     PISVPSSYNDLFETENIRNHVGWVWYEKEVTLPKRLLEERLVLRFGSATHEAKVFLNG
                     KFITQHKGGFTPFESEINRFVKDGNNRITVAVNNIIDDSTLPVGIMKETVQENGDIKK
                     ENLVNFDFFNYAGIHRPVKLYTTPKDYISDITINTRITDLDASVEFNIDTEWTGKILI
                     AIYDEEAQLVAEAEGKKGMIQLKNPIFWEPLDAYLYSMKISLIDDNKVIDTYTEEFGI
                     RSVQVTNGKFLINNKPFYFKGFGKHEDSYVNGRGLNEAVNIKDFNLMKWIGANSFRTS
                     HYPYSEEIMRLADREGIVVIDEVPAVGLHLNFMATLLDDNVEKHNTWKEIRTENSHKT
                     VIKELIERDKNHPSVVMWSIANEPDSDSEGAKEYFEPLVELTKELDPQKRPVTIVTYL
                     KSTPDVCKVGDIVDVLCLNRYYGWYVSGGDLAHAKYLLKKELDGWMERCPDTPIMFTE
                     YGADTVAGFHDTVPTMFTEEYQVAYYEANHEVIDTCENFVGEQVWNFADFATSQGILR
                     VQGNKKGIFTRDRKPKMIAYYLQKRWSSIPNFSYKK"
     gene            complement(5703..7469)
                     /locus_tag="RD451_002329"
     CDS             complement(5703..7469)
                     /locus_tag="RD451_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-hexosaminidase"
                     /protein_id="HDT7567545.1"
                     /translation="MTIKVDLRKKPYNLDEDAISWIEETIDSMTLEEKIGQLFVNMGS
                     SRDKNYLSNMVNQYHIGAVRYNPGTADEVYDQNYILQTESKIPLLIAANTEAGGNGAC
                     TDGTEVGVEVKIGATNDAKYAYELGRVSGIEASAIGCNWSFAPIVDINRNWRNPIISS
                     RSFGQNPDKVLELSLAYMKGIQESGILPAAKHFPGDGIDERDQHLSFSINSLGTEEWD
                     NSFGKVYSGLIEAGLPSIMAGHIHMPAYSKHFNPDLKDEDLLPATLSKELITDLLRGK
                     LGFNGLVVTDASHMLGMTGAMKRSELLPTSIAAGCDLFLFFNDPDEDFNYMMEGYRKG
                     IITDDRLLDALKRILGLKAKLGLHKKAKEQILLPKQEALEKIGLIENKSIFKEVADQA
                     ITLVKDKQDIWPIVPEKYKRILLVDVHGVKGGFGEVVAGNRPQAIDLLKQILSAKGFE
                     VEKYISPEEELKGLSQEEKIKNIAGIYAAKRPIKNLTKKYDLIINIANVNPGTVQRIV
                     WPASKGTPDIPFYIHEIPTIFVSVQCPFHLADVPQVKTYINTYDGKQETLEILVDKLM
                     GLSEFKGVSPIDAYCGLKDTFI"
     gene            complement(7482..8276)
                     /locus_tag="RD451_002330"
     CDS             complement(7482..8276)
                     /locus_tag="RD451_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HDT7567546.1"
                     /translation="MNNWIFCIDSDGCVMDTMTYKHNLFFGPIAAEIFDVHHREKFLQ
                     DWNNINLYSETRGINRFLGLVKTLEKNDVTSINRLKHWVSLTKELSNPSLKREIEYSQ
                     SEDLLKALKWSEEVNQQISQAKGLDKPFLSARDTIKALKKYGKIIIVSSANKEAVQEE
                     WERHELLSLVDELCCQDKGKKEDIIRSVIENGCDLDKILMIGDSPGDLEAANKNKVFF
                     YPILVNKEKESWENLRTDVLFKCLSGDYVDIEQKYIDTFWKNLTNK"
     gene            complement(8286..9662)
                     /locus_tag="RD451_002331"
     CDS             complement(8286..9662)
                     /locus_tag="RD451_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDT7567547.1"
                     /translation="MERKFGIRDKIGYMFGDFGNDFTFIFASSFLMIFYTKVLGISGA
                     AVGTLFLVARFIDAVTDVTMGRIVDRSKATKQGKFKPWILRMSGPVALASFLMYQTSM
                     ISASMSVKVVYMYVTYILWGSIFYTSINIPYGSMASAITSITEERTMLSTFRNVGATL
                     ASLVIGVLTPLFIYTRDDSGAQIVRGGSTFTIVAGIFSICALICYLICYKLTTERVRI
                     DQSQYKVSLLKSLKGLVKNRALLSIIGAAIFLLLAQLLIMSMNNYVFPDYYNDAQGIV
                     LMNFINPILVLIVVSPLTLFLSKKYGKKELASVGMFFSAIVYLILFLIKASNMYVFLI
                     LSSVGYMGLGVFNTVIWANITDVIDDQEVKSDQREDGTVYAVYSFARKIGQALAGGVG
                     GWTLSIIGYDSLANVQTGDVLEKLYNASTLIPSICFLIVGLILFFLYPLSKDKVLENC
                     ELLKQKHK"
     gene            complement(9782..10429)
                     /locus_tag="RD451_002332"
     CDS             complement(9782..10429)
                     /locus_tag="RD451_002332"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 2-keto-4-hydroxyglutarate
                     aldolase/2-keto-3-deoxy-6-phosphogluconate aldolase"
                     /protein_id="HDT7567548.1"
                     /translation="MKKVEILSKLEAAGVIAVVRGKNKDEAIKAINSIIAGGIKGIEL
                     TFTVPNAEEIIKEIAKKYADQKDVIIGAGTVLDAFTARIAIMAGAEYIVSPSFDRQTA
                     EICNLYQIPYLPGCMTITEIKEALTAGVDIIKLFPGSAFGPSIVKAYQAPLPHVNIMP
                     TGGVSIENLEDWFEVGVVAVGVGGNLLASVEKGDFEEVSRVASKYIDKFYEIKNY"
     gene            complement(10513..11940)
                     /gene="uxaC"
                     /locus_tag="RD451_002333"
     CDS             complement(10513..11940)
                     /gene="uxaC"
                     /locus_tag="RD451_002333"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HDT7567549.1"
                     /translation="MFLDKNFLLENEIAKRLFHKFAKHQPIIDYHCHLDPAYLLENKQ
                     YKNLTQVWLNDKGAGDHYKWRLMRANGIEEELISGPGDDYEKFLAFVKTVEKAPGNPI
                     FEWSHLELQRYFDIDLTISEKNAPEIWRRANEKIQTDSYRPKELLEMMDVKAICTTDD
                     PTDDLWYHTELSKQDNSFKVLPTFRPDKVWSIKSSGFSNYILKLSQTAAIPIKDFNGL
                     KQALSQRVDHFHQIGCRLADHGLNTYFYEIADEKILDNLLIKALAGKTDFHLSEIAQF
                     VTGIQLHLMSEYTRYGWTMQMHLNALRNNSSILKEQIGVDVGGDSMGDQASLTQNVVA
                     LFDTAEKSGCLPKTILYSLNPTDWLPLATAMQSFQGGMIQKIQLGCAWWFNDTAEGMR
                     QQLTTMAQQSLLSNFTGMLTDSRSFLSYPRHEYFRRVLCQLLSEWVKAGRIPDDEMYL
                     SQIVENICYRNAYNYFNFFEIGSRK"
     gene            complement(12014..13093)
                     /gene="uxuA"
                     /locus_tag="RD451_002334"
     CDS             complement(12014..13093)
                     /gene="uxuA"
                     /locus_tag="RD451_002334"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HDT7567550.1"
                     /translation="MEMTFRWYGANEEKISLQEIRQIPAMKGIVGTLMDIPAGEVWPR
                     ERIKSLKDEVEANGLTLKVIESVNVHDDIKIGLPTRDQYIENYKQTIRNLAEFGIEVI
                     CYNFMPVFDWVKSDLDYRLDDGSSTLAYISKNIPTDPEEIIREVENSTNNFELPGWEP
                     HRLSQIKQLLEAYKEVDEEKLRENFAYFLKAIIPTCEEVGIKMAVHPDDPPYSIFGLP
                     RIVKNRDDLDWLCNVVDSPSNGITLCTGSIAERPDNDVYEILSEFCQRDRIPFAHVRN
                     IKYLSDNGLDFYEAPHKSEYGSLDMYKILKTMYDNGFNGYIRPDHGRMIWGETGRPGY
                     GLYDRALGAVYLNGIWEALEKGASK"
     gene            complement(13096..14727)
                     /locus_tag="RD451_002335"
     CDS             complement(13096..14727)
                     /locus_tag="RD451_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HDT7567551.1"
                     /translation="MVSIKNWQNSIEEFNEMQILLPCFDVKEVKQEGQQHPVWLHFGG
                     GNLYRGFHAEIAQCLADQNELETGVVVCETFDEEVVEKAYHDYNNDILEIVMSGDGEL
                     KKRLLAVTADSLYCNPKNIADYQRVVKYFEDPKLQFTTFTITEKGYSLKDSKGQFFSV
                     VKADIKSGPSNPQHTMSIVTSLLYSRFNAGELPIAMVSTDNFSQNGQRFQDSIFTIAE
                     AWQKEGYVSEKFIAYLKDKEKVTFPWSMIDRITPNPSENVKEDLLMMGLEDLDIIHTK
                     KHTNIAAFTNTEVVHYLVIEDSFPNGRPKLEKAGVIMTDRETVDKADIMKVTTSLNPL
                     HTALAVTGCLLGYQSISAEMQDDDLVGLIKGIGYLEGLPVVENPGIIDPKQFIDEVIN
                     KRLPNPYIPDTPQRIATDTSQKVAIRYGETIKKYVEKDGNAENLTFIPIAIAAWLRYL
                     LAVDDQGENFVPSPDPLLVELQDKLSVLKLGEQDPSKIHCAVQEILENKEIFGLDLYQ
                     VGVGKKTEKIFCEMLVGPQAVRKTINKYITEVGGK"
     gene            15031..15702
                     /locus_tag="RD451_002336"
     CDS             15031..15702
                     /locus_tag="RD451_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDT7567552.1"
                     /translation="MTIKTSLQNQAYQSIRRQIIYADLEPGKKVSEKKLEETLSIGRT
                     PIREALIQLRQQGLVDTIPQSGNYISLIDLDSAKNARFVREHLERQIMLECCAKMNNQ
                     KKRILETIISEQEKAVSQKNARSFFHNDNLFHKACFEIAEREEVWQWLENNNTHLERF
                     RWLRVKTEGLKWEKIMEQHYQLFEALTKQDPEEANFLTSLHLHLMLNEQNIVLATHPK
                     YFKNI"
BASE COUNT         5370 a         3200 c         2222 g         5766 t
ORIGIN      
        1 gagtgtaaca taaatggctt ttttatttgt ctcgcttaat tatacaaacg gcgaagatat
       61 caatgatgat ggctcaagaa aaaaagtgga gaaagttggc ggagacaccc gaccagaggc
      121 cgaagctgct ttacgaaaag ttttatcaga tattgacgaa acaggacaat actttttagg
      181 tacggatact cgagtaaaac aataccttga tttttggatg gaggaatacg ttaaactaaa
      241 tctaaaatac aatacctatg aaaactaccg atttaccatc aaaaatcata taaacggtta
      301 tttaggaaag aaaaaactta cggatctctc ccctgctctt ttacaaaatt tcatcaatgc
      361 tgaatttaaa aagggttact cgaagaaaac aatgactatt actcactctg tccttaagaa
      421 tgcgctgaat atggcggttt atccttgggg attaatcaag caaaatccta tgctgtatgt
      481 aaaaatacca aaatatgaag cacgaccaac gactaaaaaa gatctaaaaa tcatttctct
      541 tgaggacttt gatcatatgc tagaaattac tcctgaagga catcctttct atattccttt
      601 gaatattgga ttttatacgg gaatgcgcgt tggcgaagtt tgtggtctga cgtgggatga
      661 tgtcgatttt tcaaatggaa caattactgt agagaaacaa atggtaaaga atgacggcgc
      721 atgggtatat ggtacgccaa agacaagcag ttccaatcga acgattttta ttggacaaac
      781 cttgctagca attctgaaaa aacataagaa acaacaatta gaaaatcgaa tgaagtatgg
      841 aaagctctac attgattcaa atgcagtatg tacgaaggaa gacggtgagc tagttacgcc
      901 aagtgtagtg aaatggaata ctaggaggat atcgaatgca ctctccctct cttttaactt
      961 ccattctctc agacatactc atgctacact tcttctcgaa aatggcgcaa aaatgaaaga
     1021 aatctctgaa cgattgggcc acagcagaat ttcaattacg atggatactt actcgcatgt
     1081 aacagataag atgagaaatg aaacggtcga tatcatggaa aatcttagaa agaattcttg
     1141 atttttgcca ccgaaaaaaa ccaccggtgg caaaccggtg gcaaatccat gtaaacatgg
     1201 tttatttttt acactgtttt caaacaaacc cttgctattt cttcggttcg tcctcgtcca
     1261 ttttcgatac cgacagctag cttataaccc aaggtatatc aacataaaaa aataaaaata
     1321 ggctatgaca gcagcgtgac agcaaaaaag atggaaagtt aaatatcaaa cctcgtaatt
     1381 tcatttgcga gtgcttgatt tgtttctgga tataagtgtc catatttgtc caaagtagtt
     1441 ttaatagagg catgacctag acgcttagat attgcataga tatttttatt atgttcaatt
     1501 aaaaaggcaa catgcgagtg tcttaatcca tgcatatgaa ttggttttac tcctgcaatt
     1561 tcagctagtt tttttattct gcttaaaata gttcttggag atggcggtaa tccatcaaaa
     1621 gaaaaaacca attctatatt tttcccaatt gattgttgag tttttttcca tgtttttaaa
     1681 tcttcaacgg tttgtctgtc taacgaaatt atccgaatac ttgatgtatt ttttgtttca
     1741 gcaaattcat aatcttgtct tgtacggatg taaattgact tatttacgct acatctgcca
     1801 tttattaagt caaagtcttt ccattgtaac gctaagagct cctcactcct tacacctgta
     1861 acaaaaataa aacgcatcaa acgtttataa aattcttcat aaaaatcccc gtgataaaca
     1921 ctattatata ctttcttaaa ttcatcaact gtccaaaatt ctacttgagg acgctgagtt
     1981 tttattttac ctatagtatc tacaggattt tcttcaataa tttcaagtac aattgccctt
     2041 ttaaaaacta ctctcaactt attgaatatc tgtttaatat aatttggtga taatggttgc
     2101 tcaatgccct tttttacaac atggattttc gataaaaact gttgaaattc ctgtatatga
     2161 attggtcgaa tctttacaac ctgcatttct ccaaaaaaat ccaatgcacg ttgtaaaata
     2221 tgatctgttt tcatatatgt tttttctaca gttcccaact tataccaagg aaaaaaatac
     2281 tctcgataaa aatcatgaaa cgttattcct tgcagataaa ttccttgtga atcagaaaaa
     2341 ctttgtttta actcttcgag tccccttcta gcttctcctt gagttttgaa gcctcttctg
     2401 gtcacttgaa ttctttttcc aaagcgatct tgtcctaaag ttgcagaaaa aaaccaagtg
     2461 cctctttttc tgtctttata aacattcgca attttcctca ttttactatt cctcccaaga
     2521 aatatggaga acttcttcta aaattgaaat aggaattctt tttatttttg aattacgata
     2581 aaaaaagtat cctttctcaa ctaaaagttc tttacattcc ttgaagattt tattagcata
     2641 gtactgagaa aaacctagat taatcaaatc ttttcgagta gctgttttca ttatagcacc
     2701 ttccttactt tttttcattt atttctatca gctgcttttg tcaaaagcac ataggaattt
     2761 cacctctccc caagtttacg gcgagcctta cggaagtatc attatcccaa ctttaaatca
     2821 tcgcttttta ttgactataa aaattatttt agaatattta tcgctccttc tttacagcaa
     2881 gaaatcatgg cgcaactaaa atatgctcct taaagtgtta acgtactgat agaatctatt
     2941 taattttcaa tgaacaatag gttttctacc taaaagaatc tactaattcc ttaactatta
     3001 gaagattctt ttaaacagaa aaagtggaaa ggggattttt ttaattagtt aattttaaat
     3061 tttaagatcg cttctattaa tttaatttct agctgactta tcatatattc atctacatag
     3121 gtaacgaatt gacctacctc gttaaatcca tttgtcaaac ataacttagc catataagaa
     3181 tgataatgtt tgagtatcat cttgatcgaa attggatctc cttctagagc agataagata
     3241 atggatagtg gaactaatag gtactgccgc tttttagatt tatctaccat aggtcatacc
     3301 ccattttcaa ttgttcaact gccttctttc gttgatacca gataccactt gtgctcatat
     3361 tgagaatttt accgatttca gcatcattaa aacctgcaaa ataataaagt aggataatct
     3421 ttcttcttat ctccgataac tgatcaattg ctgctgataa cttttgatct gaaattaata
     3481 tttccattcc aaataagaaa tagacatctt gttcatcaaa atgagtttgg gaatacctgc
     3541 cttcatttga atctgccaat ggttcctcat tatcctttat gttagcgttt cgttttcgaa
     3601 tagacttagc ttcgtttcgt aatacttttt tacagtaggc atcaaattgg tgttgtatag
     3661 atatgtcatt gtaatgttgt tgcatgataa tatgctcctt tttccccctt tccactaata
     3721 caacaatcag aaagcccctt tttttcgaaa aaactagaaa aaaaacataa aaatatttat
     3781 cattctttaa acagaaaatc tttctataaa aaacaaaaaa aaacgattag gctaggctaa
     3841 tcgttttttg aacattctta aaaaatccaa attatttttt ataactgaaa ttgggtattg
     3901 atgaccatcg tttctgtaga tagtaagcaa tcattttagg ttttctatct ctagtaaaga
     3961 ttcctttctt atttccttgc actcttaaaa tcccttgact tgttgcaaaa tctgcaaaat
     4021 tccacacttg ttcaccaaca aaattttcac atgtatctat tacttcgtga tttgcttcgt
     4081 aataagccac ttgatactct tctgtaaaca ttgttggtac tgtatcatga aatccagcta
     4141 ctgtatctgc tccatattct gtaaacatta ttggcgtatc aggacatctt tccatccatc
     4201 catctagctc ttttttcaac agatattttg catgtgccag atcccctccc gaaacatacc
     4261 aaccataata acgatttaaa cataaaacat cgacaatatc tcctacctta caaacatctg
     4321 gcgttgattt tagataagta acgattgtta caggtctttt ctgcggatca agttctttag
     4381 ttaattcaac taaaggttca aaatattctt tagcaccttc ggaatccgaa tctggttcat
     4441 ttgcaataga ccacattaca acacttgggt ggttcttgtc gcgttctatc aattccttga
     4501 tcaccgtttt atgagaattt tctgttcgta tctctttcca cgtattatgt ttttccacat
     4561 tatcatctaa taaagtggcc atgaaattta aatgtaaccc tactgcaggt acttcatcaa
     4621 taactacaat accttctcga tctgctaatc gcataatttc ttctgagtaa ggataatgtg
     4681 atgttctaaa agaattagca cctatccatt tcattaaatt aaaatcttta atatttacag
     4741 cctcattcaa accacgtcca ttaacatacg aatcctcatg cttaccaaat cctttaaaat
     4801 aaaaaggttt attattaatc aaaaatttgc cattggtaac ctgaacactg cgaataccaa
     4861 attcttctgt ataggtatcg atcactttat tatcatcaat taaactaatt ttcatactat
     4921 ataaataagc gtctagaggt tcccaaaaaa ttggattctt aagctgaatc attcctttct
     4981 ttccttcagc ttcagctaca agttgagcct cttcgtcata tatcgctatt aagatttttc
     5041 cggtccattc tgtatcgata ttgaattcta cacttgcatc caaatcagtt attcttgtat
     5101 taatagtaat atcacttata tagtctttcg gagttgtata taacttaaca ggtctatgaa
     5161 tacctgcata attgaagaaa tcaaaattaa ctaagttttc cttttttata tccccatttt
     5221 cctgtactgt ttccttcata atccccacag gtaaagtact atcgtcaata atattgttta
     5281 cagcaactgt aattcgatta ttcccgtctt ttacaaaccg attaatttca gactcaaatg
     5341 gtgtaaaccc acctttgtgt tgagtaataa actttccatt caaaaaaact tttgcttcat
     5401 gtgttgcaga tccaaaacga agaactaatc tttcttctaa taatctttta ggaagagtca
     5461 cttctttttc ataccacacc catccaacat gatttctaat gttctctgtt tcaaataaat
     5521 cattataaga agagggaact gaaatcggat aactctcttt ttcatttatt ggttctaaag
     5581 caagttcttc ctgtaagtca tcatttgtat ctaatttaaa tctccagaga ccgcttaagt
     5641 caattacttg cctcgtctct gtcataatgg gatacaacat ataaaccact cctatctaaa
     5701 tattaaataa atgtatcctt taaaccacaa taagcatcta ttggacttac tcccttaaat
     5761 tcagaaagac ccattagttt gtccaccaat atttctaaag tttcttgttt tccatcataa
     5821 gtattaatat aagtctttac ttgaggtaca tcagccaaat gaaacggaca ctgtacagat
     5881 acaaaaattg ttggaatttc atgaatgtaa aacggtatat ccggagttcc tttacttgct
     5941 ggccagacaa ttcgttgaac tgtgcctgga ttaacattag ctatattaat gatcaagtca
     6001 tattttttag ttaaattttt aattggtctc ttagcagcat atattccagc tatattttta
     6061 attttttctt cttgcgataa tcctttcaat tcttcttcag gtgaaatgta tttttcaact
     6121 tcaaatcctt ttgctgacaa aatctgtttc aataaatcaa tggcttgagg tctatttcca
     6181 gcaactactt caccaaaccc accttttacc ccatgtacat ctactagtaa aatcctttta
     6241 tatttttctg gtacaatagg ccaaatatct tgtttatctt taactaatgt aattgcttgg
     6301 tcagccacct ctttaaaaat tgatttattt tcaattaaac caattttttc cagagcttct
     6361 tgcttaggta ataaaatttg ttcttttgct tttttgtgta atcccaattt agcttttaac
     6421 cctaaaattc tttttaaggc atctaataac cgatcatcag tgataattcc tttacgatag
     6481 ccttccatca tataattaaa gtcttcatct ggatcattaa aaaatagaaa tagatcacat
     6541 ccagctgcaa tagaagtggg caataattct gatcgtttca ttgccccagt cattcctaac
     6601 atatgactag catcagtaac tactaatcca ttaaatccga gttttcctct aagtaagtca
     6661 gtgattaatt cttttgataa agttgcagga agtaaatctt catctttcag atcaggatta
     6721 aaatgttttg aataagctgg catatggata tgacctgcca taattgaagg taatccagct
     6781 tctattaagc ctgagtatac ttttccaaaa gaattatccc attcttccgt acctaaacta
     6841 ttaatactaa aagatagatg ctgatctcgt tcgtcaatac cgtcaccagg gaaatgttta
     6901 gctgcaggca aaattccact ctcctgaata cctttcatat aagctaaact aagttctaaa
     6961 actttatcag ggttttgtcc aaaagatcga ctagaaatga taggatttct ccaatttcta
     7021 ttaatatcta caataggagc aaaactccag ttacatccaa tagccgatgc ttcaatccca
     7081 gaaactctcc ctaattcata agcatatttc gcatcatttg ttgcaccaat ttttacttct
     7141 acaccaactt cagtaccatc tgtacaagct ccgttaccac ctgcttccgt attagcagca
     7201 attaatagag gaattttact ttctgtttgt aagatatagt tttgatcata tacctcatca
     7261 gcagttcctg gattatatcg tacagctcca atatggtact gattgaccat attactcaag
     7321 taatttttat cacgactaga tcccatatta acaaacaatt gacctatttt ttcttccaaa
     7381 gtcatagaat caatcgtctc ttcaatccaa gaaatagcat cttcatctaa attatatggt
     7441 ttttttcgta aatctacttt tatagtcatt ttctttctcc tctacttatt agtaagattt
     7501 ttccaaaaag tatctatata tttttgttca atatctacat aatctcccga taaacattta
     7561 aataaaacat cagttcttaa gttttcccat gattcttttt ctttattgac caaaatagga
     7621 taaaagaaaa ctttattttt atttgcagct tctagatcac caggagaatc accaatcatt
     7681 aatatcttat ccaaatcaca accattttca attacacttc gaataatatc ttcttttttt
     7741 cctttatctt gacaacacag ttcatcaact aatgataata attcatgtct ttcccattct
     7801 tcttgaacag cttccttatt agctgagctt acaataatta tcttcccata ttttttcaga
     7861 gcttttatag tatctctagc acttaaaaag ggtttatcta atccttttgc ttgactaatc
     7921 tgttgattga cttcttccga ccattttaaa gcttttaata aatcctctga ctgagaatat
     7981 tctatttccc tcttcaaaga tggattagac aattcttttg ttagagatac ccagtgcttt
     8041 aatcgattaa tcgatgttac atcatttttt tctaatgttt taactaaacc taaaaatctg
     8101 tttattccac gagtctctga atataaatta atattattcc aatcctgtag gaatttttct
     8161 ctatgatgaa catcaaaaat ctctgcagca attggtccga aaaagagatt gtgtttataa
     8221 gtcatcgtat ccataacaca gccatctgaa tcaatacaaa atatccaatt attcatattt
     8281 ctctcctatt tatgtttttg ttttaaaagc tcgcaatttt ctaagacttt atctttagat
     8341 aatggataaa ggaaaaataa aattaatcct acaatcagaa aacaaattga tggaattaat
     8401 gttgaagcgt tatataactt ttctaaaaca tctcccgttt gtacatttgc taaagagtca
     8461 tagcctataa tagaaagagt ccaacctccg acgcctccag ctagagcttg acctattttt
     8521 ctagcaaaag aatataccgc atatacggtc ccatcttctc tttgatcaga ctttacttct
     8581 tgatcatcaa taacatcagt aatatttgcc caaataacag tattaaacac acccaaaccc
     8641 atatagccaa ccgaactaag aattaagaat acatacatat tactagcttt tatcaaaaat
     8701 aagatcaaat atactattgc tgaaaagaac attcctactg atgccagttc tttttttcca
     8761 tattttttac ttaaaaacaa agttaaaggc gaaacaacta ttaaaaccaa aataggattg
     8821 ataaaattca ttaaaactat tccctgtgca tcattatagt aatcaggaaa tacataatta
     8881 ttcatactca taattaataa ttgagcaagg agtaagaaaa tagccgcacc aattatagaa
     8941 agtaatgccc tatttttaac taaccctttt aaagatttta acaatgaaac tttgtattga
     9001 gattggtcaa ttcttactcg ttcagtagtt agtttataac atattaaata acaaataagt
     9061 gcacatatcg aaaatattcc cgcaacaatt gtaaaagttg atccaccacg aactatttga
     9121 gcgcctgaat catctcttgt ataaataaat aatggtgtta atacaccaat gaccaaactt
     9181 gctaaagtag ctccaacatt tcggaatgtc gatagcattg ttctttcttc tgtaatagaa
     9241 gtaatagctg atgccattga tccataagga atatttatag atgtgtaaaa aatactcccc
     9301 cataatatat acgtaacata catgtatact accttaacgc tcatagaagc tgaaatcata
     9361 gaagtttgat acattaaaaa acttgctaaa gcgactggac cactcattct taaaatccac
     9421 ggtttaaact taccctgctt agttgctttc gatctatcaa caatacgccc catagttaca
     9481 tcagtaactg catcgataaa tcttgctact aaaaataatg ttccaacggc agctccgctt
     9541 atccccaata cttttgtata aaagatcatt aaaaaagaac tagcaaaaat gaaagtaaaa
     9601 tcgtttccaa aatctccaaa catatatcct attttgtctc ttataccaaa ttttctttcc
     9661 atacaattct ctcccttctg ttgttaagcg ttttcattct gatgaaagta cgtactatac
     9721 tctgaagcgt aaagagtcag tatttatttt ttacatttca gagtattatt tgttttttct
     9781 cctaataatt ctttatctca taaaacttat ctatatattt actagctact cgacttactt
     9841 cttcaaaatc acctttttca acagaagcca ataaattccc acctacacca actgcaacaa
     9901 ctcctacttc aaaccaatct tctaagttct ctatacttac tccgccagta ggcattatat
     9961 ttacgtgtgg taatggagct tgataggctt ttacaatgga tggaccaaaa gcagaacctg
    10021 ggaatagttt aatgatatct acgccagcag taagtgcctc ctttatctca gtaattgtca
    10081 tacaacctgg taaataagga atttgatata aattacaaat ctcagctgtt tgtcgatcaa
    10141 aagatggact aacgatatat tctgccccag ccataattgc gatacgagca gtaaacgcat
    10201 ctaaaaccgt accggctccg attattacat ctttttgatc agcatatttt ttagcaattt
    10261 ctttgattat ttcttcagca ttaggaactg taaaagttag ttcaatccct ttaattccac
    10321 ccgcaataat tgaatttatt gctttaatgg cctcatcctt atttttccca cgtacaaccg
    10381 caatgactcc agccgcttct aacttactta aaatttctac ttttttcata tctatctcct
    10441 tcctttatgg atacatactt tgtctagctg tactaactta caaagaataa atttaagctt
    10501 ttatttcaag tattattttc tacttccgat ttcaaaaaaa ttaaaataat tatacgcatt
    10561 acgataacaa atattctcca ctatctgact aagatacatt tcatcatctg gaattcggcc
    10621 tgctttaacc cactcgctta gtaattgaca taatactcga cgaaaatact catggcgagg
    10681 atagcttaga aaacttcgag aatcagtcaa catacctgta aaattcgaca acaaactttg
    10741 ttgtgccatc gtagtcaact gttgacgcat tccttcagct gtatcattga accaccaagc
    10801 acatcccaat tggatttttt gaatcatacc cccttggaag ctttgcattg ctgttgctag
    10861 tggaagccaa tcagttggat ttaatgaata taaaattgtt tttggtaagc acccactctt
    10921 ttcagcggta tcgaacaatg ctacaacatt ttgtgtcaaa ctagcttgat cccccatcga
    10981 atcaccaccg acatctactc caatttgttc ctttaatata cttgaattat ttcttaaagc
    11041 atttaaatgc atttgcatcg tccaaccata tcttgtatac tcagacatca aatgtaattg
    11101 aatacctgta acaaattgtg caatttctga taaatggaaa tccgtttttc ctgctaaagc
    11161 ttttattaac agattgtcga gtattttttc atctgctatt tcataaaaat aagtattcaa
    11221 accgtgatct gctaatcgac agccaatttg atgaaaatga tccactcgtt ggctcaatgc
    11281 ttgcttcaac ccattaaagt ctttgattgg tatagccgct gtttgactaa gttttaaaat
    11341 atagttcgaa aagcctgatg atttgatact ccagacctta tctggacgga aagtaggtaa
    11401 taccttgaaa gaattatcct gtttagaaag ctcagtatga taccacaagt catctgtagg
    11461 atcatccgtt gtacagatgg ctttcacatc catcatctcc aacaattctt tcgggcgata
    11521 ggaatccgtt tgaatttttt cgttagcacg tcgccaaatt tctggtgcat tcttctcaga
    11581 aattgtcaaa tcaatatcaa agtaacgttg taattccaaa tgagaccatt caaaaatagg
    11641 attacctggc gccttctcca ctgtttttac aaaagctaaa aatttttcat aatcatcacc
    11701 tggaccactg atcaactctt cttctatacc attagctcgc atcaatcgcc atttataatg
    11761 atctccagct cctttatcat ttaaccatac ctgagtcaaa ttcttgtatt gcttattttc
    11821 tagcaaatat gctgggtcta aatgacaatg atagtcgata attggttggt gttttgcaaa
    11881 tttatgaaaa agtcttttag ctatttcatt ctctaataaa aagttcttat ctaaaaacat
    11941 atttaaacac tcctttcctt ccgttagttt ttagaagaga aaatttttcc tctaaataaa
    12001 ctcccttata taattattta ctcgccccct tttcaagcgc ttcccaaata ccatttaaat
    12061 aaactgcacc tagagctcgg tcatataatc cataaccagg tctaccggtt tctccccaaa
    12121 tcatccgacc atgatctgga cgaatatagc cattaaatcc attatcgtac attgttttta
    12181 atatcttata catatctaga gaaccatatt ctgatttatg cggcgcttcg taaaaatcga
    12241 gtccattgtc acttaaatat ttgatattac gaacatgtgc aaaaggaatc cgatcccgtt
    12301 gacaaaattc agatagaatt tcatagacat cattatctgg tcgttctgca atacttccag
    12361 tacataatgt aataccatta gaaggagaat ccactacatt acacaaccaa tctaaatcgt
    12421 cacgattttt aacaatacga ggtaatccga aaatggaata tggtggatca tctgggtgaa
    12481 ctgccatttt aatcccaact tcttcacatg tcgggataat tgctttgaga aaatatgcaa
    12541 agttctctcg taatttctct tcatcaactt ctttataggc ttctaataat tgcttaattt
    12601 gtgataaccg atgaggttcc caacccggca attcaaaatt attagtagaa ttttctactt
    12661 ctctaataat ttcctccgga tcagtaggga tattttttga aatataggct aacgtagaag
    12721 acccatcatc taaacgataa tccaaatccg attttaccca atcaaatact ggcataaaat
    12781 tataacagat aacctcaatc ccaaattctg ccaaattgcg aatcgtctgt ttataattct
    12841 caatgtattg atctcgtgtt ggtaaaccaa ttttgatatc atcatgaaca ttaacactct
    12901 caataacttt caaggtaagt ccattggctt cgacttcatc ttttaaagat ttaattcgtt
    12961 ctctcggcca aacctctccg gctggtatat ccattaatgt tccaacaatt cctttcattg
    13021 ctgggatctg acgaatttct tgtagtgaga ttttttcttc atttgcccca taccatctaa
    13081 aagtcatttc catagttact ttcctccaac ttctgttata tatttattga ttgttttacg
    13141 aactgcttga ggacctacta gcatttcgca aaagattttt tcagttttct ttcctacccc
    13201 aacttgatat aaatctaaac caaagatttc tttattttct aaaatttcct gtaccgcaca
    13261 atgaatcttt gaaggatctt gttcacctaa tttcaatact gataatttat cctgcaactc
    13321 taccaataac ggatcaggac ttggcacaaa attttcccct tgatcatcga ctgccagtaa
    13381 ataacgtaac caagcagcaa tagcgatagg aataaatgtt agattttctg catttccgtc
    13441 tttttcgaca tactttttaa ttgtttcacc atagcgaatc gctacttttt gagaagtatc
    13501 tgttgcaatt cgttgtggtg tatctggaat atagggatta ggcaaacgtt tattaattac
    13561 ttcatcaata aattgttttg gatcaataat gcctggattt tcaactactg gtaaaccttc
    13621 taaataacct attcctttga ttaaaccaac caaatcatca tcctgcatct ctgctgaaat
    13681 tgattgatat cctagcagac aacctgttac tgccaaagca gtatgaagtg gattcaagct
    13741 tgtcgtaacc ttcatgatgt ctgctttatc aaccgtctct ctatctgtca taatcacacc
    13801 agccttttcc aatttaggcc ggccatttgg aaaactatct tcaataacta aataatgaac
    13861 tacctcagta ttagtgaaag cagcaatatt ggtatgtttt tttgtgtgaa tgatatctaa
    13921 atcctcgagc cccatcatca atagatcttc ctttacattc tctgaaggat ttggcgtaat
    13981 tcgatcaatc atactccaag gaaaagtcac tttttcttta tcctttaaat aagcaataaa
    14041 tttttcagaa acatatcctt ctttttgcca agcttctgca atcgtaaaaa tactatcttg
    14101 aaaacgttga ccattctgtg agaaattatc agtagaaacc atcgcaatcg gcaactctcc
    14161 agcattaaat ctgctatata acaaggatgt tacaatactc atcgtatgtt gaggattgct
    14221 aggtccagat ttgatatcag ctttgactac cgaaaagaat tgccctttag aatcttttaa
    14281 actgtaacct ttttcagtaa tagtaaacgt tgtaaactgt aatttaggat cttcaaaata
    14341 tttaaccact ctttgatagt ccgctatatt cttcggattg caatataaac tatcagccgt
    14401 tactgccaaa agtctttttt tgagttcacc atctccactc ataacaattt ccaaaatgtc
    14461 attgttatag tcatgataag ctttttccac tacttcttca tcaaatgttt cacacacaac
    14521 tactcctgtt tctaattcat tttgatctgc taagcattga gcaatttctg catgaaatcc
    14581 tcgataaaga tttcctccac caaaatgaag ccatactgga tgttgctggc cttcttgctt
    14641 aacttctttg acatcaaaac acggcagtag aatctgcatt tcattgaatt cttcgataga
    14701 attttgccaa tttttaatcg aaaccataat taacctcctc aaactgatat gttagttttg
    14761 atacatttta tattttaaaa cccattgtaa ccgttgtcaa tataaaaagg gaataaactt
    14821 gcttttttct accatatcag aatgattgta ttttttattc agaaaaataa aatactcctt
    14881 ctttttggac tgattttatc gaaacttatt ttttcttttt ttcatgtatt cttttatttt
    14941 tataactagt gtattacttc aaaatttgat attatatggc atgaacagaa ttaaaatatc
    15001 agttaaaata aaagttaagg agcattgtgt atgacaatta aaactagtct ccaaaatcaa
    15061 gcttaccaat ctattcgccg acaaattatc tatgctgact tagaacctgg aaaaaaagta
    15121 tcagaaaaaa aattagaaga aacactttct attggtcgta caccaatacg tgaagcactg
    15181 attcaactcc gacaacaagg tcttgttgat acaattcctc aaagcggaaa ttatatctca
    15241 ttaattgatt tagattcggc caaaaatgct cgatttgtca gagaacattt ggaacgacaa
    15301 attatgttag agtgttgtgc caaaatgaat aaccaaaaaa aacggatttt agaaactata
    15361 atttcagaac aagaaaaagc tgttagtcaa aaaaatgctc gtagtttttt tcataatgat
    15421 aatttattcc ataaagcttg ttttgaaatt gcagagcgag aagaagtatg gcaatggtta
    15481 gaaaataaca atacacactt agaacgattt cgatggctac gagtaaaaac ggaaggatta
    15541 aagtgggaaa aaattatgga acaacattat caactatttg aggcattaac aaaacaagat
    15601 ccagaagaag ctaactttct aacatcgttg catcttcatt taatgcttaa tgagcaaaat
    15661 attgttttag ctactcatcc aaaatatttc aaaaatatat aacttttaac tctttttaaa
    15721 ttaaatggtt gttctgatca gaaaaatatc gcttgttttc ttattatgta atatatttca
    15781 taaactattc tgcataacaa ctattgtttg tactttttac attggataac taattatgac
    15841 tgctgataac ttttgatatt aaactagtat ctccaataca aataaaaaat agatatcttg
    15901 ttcatcaaaa ttagttcgtg gatacttacc ttcatttaca tcattcagcg gtttcccatt
    15961 ttcttttatt ctattatttc attttctaat agacttggct tcatttcgca atactttttt
    16021 tcaataggca tcaaattggt gttgtttaga tatttagttg tagttttgtg acatgataag
    16081 tatgctcctt tttctctttt ccactaatac aacgatcaaa gggtgctttt ttcaaaaaac
    16141 tagaaaaatc aaaataagat tcgtattttg attctatata tcctgtttca actacatctt
    16201 atatttcaca atagaataaa tagccttttg catagctgct taacttataa gaaattgcaa
    16261 tttacttctt caaagtgaaa acgaatatga gtaaaataaa attattcttc ttacagataa
    16321 ttaaaaatag cgcgtaacaa aaatcggcat tcaatcacat aattaggatt gatgccgatt
    16381 acttatattc tacgtatagt tttagtattc ttatttttta tcaccagtaa ccaattgaga
    16441 acagccctaa agcagaatag tcttttatct caaaacgctt aatttcaggc ttaggaatat
    16501 gaataatctt ttgagtatat tctttctctt ttaatcttac tgaagaaata ccactgcc
//
LOCUS       DAPBAF010000055        16141 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.055, whole genome shotgun sequence.
ACCESSION   DAPBAF010000055 DAPBAF010000000
VERSION     DAPBAF010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16141)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16141)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16141
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.055"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(296..1024)
                     /locus_tag="RD451_002337"
     CDS             complement(296..1024)
                     /locus_tag="RD451_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding response regulator"
                     /protein_id="HDT7567553.1"
                     /translation="MLRIAIVDDDCTIVEGIRHYLLKKVPDIIIDHCYTDGDEAFKNL
                     QNQRFDLLITDITMGKISGLELIESLQQTSNRYFTSIVISAHQNFQYAKKGIDLSIKS
                     YITKPIDFPYLVKLVQEEKMRKSAANQNSLTDDSFNESIQQVIDYVQNNYSEKLTLKD
                     VATQFHYHPAYLGRAFKKETGYSFHDYLLDFRIKRASALLKDTFLSIDEISQKVGIDH
                     VSYFSVLFKKTTGHSPSNYRKKLL"
     gene            complement(1002..2576)
                     /locus_tag="RD451_002338"
     CDS             complement(1002..2576)
                     /locus_tag="RD451_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HDT7567554.1"
                     /translation="MKNDLSKVIMRFTYILIFFITLLACFTLFFSYINVIEKEKNQNL
                     QNIQQITHYMETYNRILSGIVTEIYQNYDFQENLNDYYLSSPAEYMEDILSKDRSPTY
                     LVDNLKKLVQDDEVKNISISLDYEKYLSAYAPTKNEKISFIRSLSFISEDMPDATLIL
                     DVSINALKKSLFPTHYNYSLSNGIDSVNLSEDISPSKWKKTQQIAIGNHTLQVYENPN
                     YSSQTLLGLAIMIFLLMSLFILAIHQLLNRSFRNYIQQYQEIITSLNHSSTGDYKSIN
                     IENKVGDLKEIAMHINQFYLDNATYQKTLYENNWLKQEAKYAALQYQIEPHFLFNNLE
                     FIRMTAILNDDEEISDSIYLLSKLYRNNTYQPDIIDLKEELINIDLSLQLHQRRYRHN
                     FDYQLIDHIDQLMLPKLSLQPFVENYIKHGFDSSKKENRLTVYATETTNHYVLKIVEN
                     GKGMDQDKLEHIQQKLNDDIPYSENIGISNSFRRIKHLYPGDTRFVIESQLHVGTTIT
                     IKIQKGGNMHVENCNC"
     gene            2805..3743
                     /locus_tag="RD451_002339"
     CDS             2805..3743
                     /locus_tag="RD451_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDT7567555.1"
                     /translation="MKLKKGLLGNLKKNRALFIILLPGALWLFIFCYIPMFGVVIAFK
                     DFRISSRGFFTSLFNSPWVGWENFKYLFASQDAWIITRNTVVYNVVGILLSTFCTVSL
                     AIILSQMANKRLLKKMQTFMIFPNFLSWVVISYFVYAFLSTDKGLINILLSNFGVEPI
                     NWYSEPKYWPFIIVFTSLWKGVGYGSIIYYASIMGIDTSYYEAALVDGASKWQQIRNV
                     VLPHLRSIIVIMLILSVGSIFRADFGLFYQLPRNSGALYDVTNVLDTYVYRGLMNSGD
                     IGMSTAAGLYQSSVGFVLILITNKIVNKLDPSSALF"
     gene            3755..4666
                     /locus_tag="RD451_002340"
     CDS             3755..4666
                     /locus_tag="RD451_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDT7567556.1"
                     /translation="MISKLKRQMYFSLPVERFFTILLILFTLSCIFPFIFVIVISLTD
                     EKALQLNGYELLPAQWSTDAYQYLIQDGGQLLRSLGVTIMITVIGTLITVFMTGTYAY
                     VLSRASFPYRKFFTFYLFFTMLFAGGMVPSYLVMTKMLGLKNTIWALILPLAFSPYNV
                     IILRTFFKKSIPESIIESAKMDGCSEFRVFFQIVLPLAIPGVATIGLFSSLGYWNDWF
                     NALLYIDTNKLIPLQYLLMKIQNSMEFLANNNDITLAQQQAIQNSLPQESTRMAMVVV
                     ATLPIAIVYPFFQKYFVQGLTIGGVKE"
     gene            4690..6162
                     /locus_tag="RD451_002341"
     CDS             4690..6162
                     /locus_tag="RD451_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HDT7567557.1"
                     /translation="MKKNMQKYLIGGASVLTLGLLGACGSSNGEANNETGTTKVTWYQ
                     VGEEPKDFDEVMTKVNEKLKEEINVELDMRLIPDGDYQQKLGVMINSGEEYDICFVNG
                     TDYVNYGNKGAFISLNDHLDKELKDYAAELNEGFIEGGAINGETYGLPVNNDIATTEY
                     WTFNKDLVDQYQLDVENVEGVETLAPVLEKFAEKNTDTNITPIGMTRTSVCIPYDNII
                     GGGVPLAVAFEGDTQTVVNTYETPEMMTYLKAMHEFYKKGYILKDAATVTTDPFRIDS
                     KNWFLGRNSSGYQPLAQKKLEALAGHGLILKPAGKAFKTTGFARVAMHAVSASSKHPE
                     AALKLLNYVNTNQEVADLMVYGIEGKHYDRNEDGSITLTNSDDYYQGAWALVNTYLVS
                     KTSPITEESKKLEEESKKFQNEAPMSPILGFSFDASDFRTEIASVQNIVSQYEVLLSS
                     GTVDPEQYVPELLEKLEKAGLDKIQASAQEQYDEWRKSNK"
     gene            6213..6824
                     /locus_tag="RD451_002342"
     CDS             6213..6824
                     /locus_tag="RD451_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HDT7567558.1"
                     /translation="MNENKWTKGFNWVFQLLLLNFTYFILICLGFGILGFFPATIALI
                     AGVVNRKKYGLQESVKFMSKIYKKNFVRYNLYCWSATLLLAGNITTIWLCWQQSAPLF
                     YLLSTLLSVITLFLVFAMLNWVVIKSLGLWMMGDRLIDYLLFTATMLPTVVMQGLVLG
                     IYFRILMILPVIFLFGGTAVTVILISKLTERALAKLPCQIQSH"
     gene            6854..8767
                     /locus_tag="RD451_002343"
     CDS             6854..8767
                     /locus_tag="RD451_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 20 glycosylhydrolase"
                     /protein_id="HDT7567559.1"
                     /translation="MKLTDKQVANIAFIQQLEIPLTQKDEEQIDLIFTDTKANVRQIK
                     ITKNEQQRICLSYSHEDLLYRGLFICLPRFLAQGGEMPYIEETSIIETSYSLDASRNG
                     VMNKETLKKFISYLALMGYNTLYIYTEDTYEVEDLPYFGYLRGAYTKEEVNEIVEFAS
                     GFGIEVVPSIQTLAHLTQFLKWYAQQELMDDQNTLLIGEEKVYAAIEKMIIACKEMYQ
                     TERIHLGMDEAYQAGLGRYLSLYGYCDRTTLMIQHMDRVLSIVDKYKMKPMIWSDFIY
                     KLLDETGKDRYYNPDFKLKALAAKGLPAGLTYVHWDYGSDEVSSYEKVIDNHLKFCDI
                     DHYVLASGAHIWGRLAPNHGKTEAIVSAAVKASKNKGVRSVMLTTWGDEGQETEHWHS
                     LIGALKLADYVYSEEEWNDFEEIYDRLLGTGSYQLMSELRYFDEVDTITNNNLQMASV
                     SKLLLWQDPLVGIYDFHVAAHNKIATRTIGTYYHELAQKLDMNKNWNPKQPILTTIRQ
                     RYILLAEILAQKAELGIYLQHCCLVEDLAGLMELANRCEALANRVNELASIHEIIWYQ
                     TYKTYGWEVLEQRYAALAHRLKTVARRIKNHLQGQDALEELLEERLPFCQYQVPLEIS
                     GFNYRQSSVSGYN"
     gene            8895..11876
                     /locus_tag="RD451_002344"
     CDS             8895..11876
                     /locus_tag="RD451_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 42"
                     /protein_id="HDT7567560.1"
                     /translation="MLSDYYQNLSVISVNTEPLRNYYIPYASKEEAKQELEREKTSQF
                     IDLNGTWDFQYYPSVQQLPENFFQEAFTESYDRISVPGVWQTEGFDLPQYINVSYPIP
                     FDPPYVPNDTPCGVYRRQFQIEQTDARFYLNLEGADSNCFVWINRNFVGYDQVSHSTS
                     EFDVTKYLQVGVNEIQILVMKWCDGTYFEDQDKWRMSGLFRPVYLLQRPTMHLTSYQL
                     RTLTDPKKGSGTLMVSFQRFTPIEVSLPISYELFHPDGRLIAKGECYSEQQINLDVED
                     CLFWTAETPKLYTLLLTCNGEYFKEKVGFRALTIKNRKLLLNGTPIKLYGVNYHDVNQ
                     QGTPVMTREQLRADLLLMKKLNVNTVRTAHYPKSPDFYELADEIGLYVINEADLECHG
                     VVNLYDTEANYQLIANDPTFEKPIMDRVIRSILPYQNRSSIIMWSMGNESGYGVNFEK
                     AQALARKLDDSRLIHNERSIEPVIDQVNDFSNLDVISQMYPPLEDVHRHCQRSDTEKP
                     FFMCEYSHAMGNGPGDLKTYFDLIQQYDSFLGGCVWEWTDHAINRGTLETPSYLYGGD
                     FGEKYHDGNFCVDGLLTPDRQLTVGALEYRNIHSPIQLIAVDEELQEVTLSNITAFTA
                     GSAFNLSLEWYIDGKKTVYEVMNPFILEPGKSCSLPITVPTTIHGAHTVAVSLSVYKN
                     DELYGQQQLFLKKEKMRLPRTAHHNDAPQISVKGTELIIKGESFIYIYQLAKAAFTSV
                     KINQKELLERPTQFSIWRAPTDNDRNLVNKWKAAGYAEMSLEIRKKDWKFVDDHLLIE
                     TSYRGVIPGLQPIFTMHIQLKINGAGVINQKVSVEKNPIFPDFPRFGMDWPLNDTFSK
                     VSYCGYGPYESYPDKHYAAMFGIYEMEIEEFDQPYIKPQEYGNRWQCDWVSIKNHQGS
                     TMTVYGNSNFSALPYSQAQLTEKSHHYELIKENRTWFNLSYKQNGIGSHSCGPYLEDR
                     FRFMEDTFDWNIVITFKGENR"
     gene            11873..13534
                     /locus_tag="RD451_002345"
     CDS             11873..13534
                     /locus_tag="RD451_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronate lyase"
                     /protein_id="HDT7567561.1"
                     /translation="MKETKINQVKKKLSRYQEVVYRNHCLKWSKNKLNVRFNGLFYRF
                     EQLEEVWKPVTNFQSCPVQLINDPKETYDLCITHLYNQHLKNDGFYLKVTNDNQLTIE
                     SANLRGFQYAMEALLESFFSVGDQLLLPELILKHEPSVKIRGIIEGFYGIPWTHEMRL
                     SLFSYMKDNQLNTFMYAPKDDELLRKKWRELYDAQELDKFKELLSAAEASNIDFWYLI
                     SPGNDIDITCEEDIQVLLKKLEQLIELGVFQFGLLMDDIDYQLKGAAKRRFREPAFAH
                     AYLVNRVEEYLSTRLSNHELVICPTEYDNRHGSRYLATLSQEIPEQLPFFWTGPSTLA
                     ASISTEELQEMASVYQRPMLIWDNIPVNDYLEDKELLFMSPYENRTPNLSKERYQVTG
                     VVSNPMAQLEASKFTINSMANYLWNCERFDPLETWTSVVEKVVGSKLQPAYLTLTNAF
                     PNHYTSSLLSDEELLLAKDPEWVTKEMAALVQAVKWIQQEQHTSRLRTELEPWLQAIT
                     ESWTFWQEWQLKKDPKEAEEWLAKKKTHRIGRDLVTAHLEQIIKS"
     gene            13574..14506
                     /locus_tag="RD451_002346"
     CDS             13574..14506
                     /locus_tag="RD451_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005229489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HDT7567562.1"
                     /translation="MVKRLISANYSDVKKMTSKELKQSIKASEGRVIVCETVANTLPQ
                     SGEITNAEVASAFGADLILLNGFDCYRPAVFGLPNVTIEKVFDLQQTIENPIPKLKEL
                     VGRPVGINLEPIAPKTNMMSEKVEISQGRASSVETIQKAEELGVDFICFTGNPGTGVT
                     NLEITKSVKMAKKYFSGLIIAGKMHSAGSEEPVVNKEAIISYAEAGADILLVPSVGSI
                     PGFLEQDLIEAVRLAKKYDLLTMSAIGTSQESARPETLRQLAIMNKSCGVDLQHIGDA
                     GYGGLAPAENIFETSVAIRGMRHTINCVSRSINR"
     gene            complement(14898..>16141)
                     /locus_tag="RD451_002347"
     CDS             complement(14898..>16141)
                     /locus_tag="RD451_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HDT7567563.1"
                     /translation="ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCL
                     THYQHTYCCKSCEKEGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQE
                     NYWKQTHGLDISRDNITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESA
                     KTDTYYWQFCTGKDSQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESV
                     RLVYCFAHVRRKFFEAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQ
                     QELRPLFIAFYEWMATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERN
                     IKELVIGRKNWLHSTSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLS
                     AETLDQLLPWNKDVQQHFSRN"
BASE COUNT         5189 a         2618 c         3217 g         5117 t
ORIGIN      
        1 atttaaataa ctacatccat ttattctatc ttctaaaata gcctttttca tttcagttaa
       61 atagttcagc gccatttttg cactcgactt gcatagtagt tttttccata ttcctcaacc
      121 tcagcggggg ttgaagacat aaggaaaatc ctatgcgtta tgctcaactg gatctgatta
      181 aatattctaa tgtatttttc tctaccatca ttaaatggtt aatagccaaa aatcaccact
      241 tttcaatggc tccttgttgt ataagtataa ctagaagatg aacacgtctg agaaattata
      301 gaagcttttt acggtaatta ctggggctgt gtccagtagt ttttttgaag agaacagaaa
      361 aatagctcac gtgatctatt cctacttttt gactaatttc atcaatagat aagaatgtgt
      421 ctttcagtag agcacttgct cttttgattc gaaagtctag caagtaatca tgaaaggaat
      481 aacctgtttc ttttttgaag gcccgtccta aataagcggg atggtaatgg aattgtgtag
      541 ctacatcttt gagcgtaagc ttttcactat aattgttttg aacgtaatca atcacttgtt
      601 gaattgactc attaaaagaa tcatcagtta gagagttttg attagctgct gatttacgca
      661 ttttttcttc ttgtactaac ttaactaaat aaggaaaatc aatgggtttc gttatgtaac
      721 ttttaataga taaatcaatc cccttttttg catactgaaa attttggtgg gcactaatga
      781 caatactagt aaagtagcga ttggatgttt gttgcaaaga ttcgattaat tcgagtccag
      841 aaattttccc catcgtaata tctgtgataa gtaaatcaaa gcgctggttt tgcaggtttt
      901 taaatgcttc gtctccgtct gtgtagcagt gatcgataat gatgtcgggg actttcttca
      961 aaagataatg ccttatgcct tctacaattg tacaatcatc gtcaacaatt gcaattctca
     1021 acatgcatat tccccccttt ttgtattttg atagtaatcg ttgttccgac gtgtagttgg
     1081 ctttctataa caaaacgtgt atctccagga tagagatgct ttatacgtcg aaaagaattt
     1141 gagatgccga tattctcact ataaggaata tcatcattaa gtttttgttg aatatgctcc
     1201 agcttgtctt ggtccattcc tttcccattt tcaacgattt ttaacacata atggttggtt
     1261 gtttcagttg catagacagt caaacgattt tccttttttg atgaatcgaa gccgtgttta
     1321 atataatttt caacaaatgg ctgtaaagaa agttttggta acattaattg atcaatatga
     1381 tcaatcagct gatagtcaaa gttatgtcga taacgacgtt gatgtagttg caaggagagg
     1441 tcgatattaa ttaattcctc tttcaaatca attatgtcgg gctgatatgt attattgcga
     1501 tacaacttgc tcaataaata tatactgtcg ctgatttctt cgtcatcatt caatatggca
     1561 gtcattcgaa taaattccaa attattaaat agaaaatgag gctcgatttg atattgaagt
     1621 gctgcatact ttgcttcttg cttcaaccaa ttattttcat aaagtgtttt ttgatatgta
     1681 gcattatcta aataaaactg attgatatgc atagcgattt ctttcaaatc accgactttg
     1741 ttttcgatat tgattgactt gtagtctcct gtagatgaat gatttaagga agtaatgatt
     1801 tcctgatact gctggatata gttacgaaaa cttctattta ataattgatg aatagcaaga
     1861 ataaacaaac tcattaataa gaaaatcatg attgccagac ctaataaggt ttgtgacgaa
     1921 taatttggat tttcatatac ttgtaatgtg tggttaccga tagctatctg ttgcgttttt
     1981 ttccatttag aaggcgagat gtcttcagat aaattgacgg aatcaatacc attagacaaa
     2041 gaataattgt aatgtgttgg aaagagactc ttttttagcg cgttgatcga aacgtctaga
     2101 atcaatgtag catcgggcat gtcctcacta atgaaactta atgaacgaat aaaagaaatt
     2161 ttttcgtttt ttgtaggtgc gtaggcactt aagtattttt cgtaatctaa tgagatagat
     2221 atatttttaa cttcatcatc ttgcacaagt ttttttaagt tatctactaa ataggtaggg
     2281 gagcgatcct ttgacaaaat atcttccatg tattcagcag gtgatgagag gtagtagtca
     2341 ttaaggtttt cttggaaatc ataattttga tagatctctg tcacgatacc ggagagaata
     2401 cgattatatg tttccatata gtgggtgatt tgctgaatgt tttgcaggtt ttgatttttt
     2461 tctttttcaa tcacattgat ataggaaaag aacaatgtga aacaggcaag taaagtaata
     2521 aaaaaaatca atatgtatgt aaaacgcata ataacttttg ataaatcgtt tttcattcaa
     2581 agtcctcatt ttgataatct ctaattttat gaatcattat agcacatatt acaagtgatg
     2641 taaacgcttt gcaaacaggg ctacttatga ttgtgaatac agtttccgtt taaaaactat
     2701 tctattgtag aggtttaata aactaaaaat aatgtataaa aaattaatgt aagcgattaa
     2761 ccaagtgggt ataatcaagg aaacgctgag agaggagaga caaaatgaag ctaaagaaag
     2821 ggttattagg aaatctaaaa aaaaaccgag cattgtttat tatactttta ccaggtgcgt
     2881 tatggttatt tatattttgc tatataccaa tgtttggagt tgtaatcgct tttaaagatt
     2941 tcagaatttc atcaagggga ttctttacaa gtttgttcaa cagtccttgg gttggctggg
     3001 aaaatttcaa atatctcttt gcttcgcaag atgcttggat cattactcgc aatacggttg
     3061 tttataacgt tgtaggtatt ttgctaagta ctttttgtac agtgtcatta gcaatcattc
     3121 tgagccaaat ggcgaacaaa cggttattga aaaagatgca gacatttatg atttttccta
     3181 attttttatc atgggtagtc atcagttact ttgtttacgc atttttgagt acggataaag
     3241 gattaattaa tattttacta agcaattttg gtgtggaacc cataaattgg tatagtgaac
     3301 cgaagtactg gccttttatt attgttttta cgagtttatg gaaaggcgta ggctatggat
     3361 ccatcattta ttacgcgtca attatgggga tcgatactag ttattatgaa gctgctttag
     3421 ttgatggtgc cagtaaatgg caacagataa ggaatgtagt cttgccacat ttaagatcga
     3481 ttattgtcat tatgttgatt ttgtctgttg gtagtatttt tcgagctgat tttggattgt
     3541 tttatcaatt gccaagaaat tcgggggctc tttatgatgt gacgaatgta ttagatactt
     3601 atgtctaccg tggattaatg aatagcggag atatcggaat gtctacggca gcgggattat
     3661 atcagtcatc agttggcttt gtcttgattt tgattactaa taagatagtc aacaagttag
     3721 atcctagttc agcactattt taggaggaat caaaatgata tcaaaattaa aacggcagat
     3781 gtacttttcg ctgccagtcg aacggttttt cacaatatta ctaatcttat ttactcttag
     3841 ctgtattttt ccctttattt tcgtaatcgt catttcatta acagatgaaa aagcattaca
     3901 actcaacggt tacgaattat tgccggctca atggagcact gatgcatatc aatacttaat
     3961 acaagatggc ggacagttac ttcggtcatt aggcgttaca attatgatta cagtgattgg
     4021 aacgttgatt actgttttta tgacgggaac ctatgcttat gttttatcaa gagcctcttt
     4081 cccttaccgg aagttcttta ctttttatct tttttttacc atgttatttg cgggagggat
     4141 ggttccttct tacttagtga tgacgaagat gcttggctta aaaaatacaa tttgggcttt
     4201 gattctacct cttgctttta gcccatacaa tgtcattatt ttaaggacat tctttaagaa
     4261 gtcgattcca gaatcgatta tcgaatccgc taaaatggat ggctgtagtg agtttcgagt
     4321 ttttttccaa atcgttttgc ctttagcgat cccaggggtt gcaacaatag gtttattttc
     4381 aagcttaggt tattggaatg actggttcaa cgcattgctg tatattgaca ccaacaaatt
     4441 gattccattg caatatttgt taatgaagat tcaaaattca atggaattct tagcaaataa
     4501 taatgacatt acattagcgc agcaacaagc aattcaaaat agccttcctc aagaatcaac
     4561 acgaatggca atggtcgtag tagctacttt accgattgca attgtttatc cgttcttcca
     4621 aaaatacttt gttcaaggat tgacgatcgg tggagtgaaa gaataaaaaa gaataggaga
     4681 tgttaaaaga tgaaaaagaa catgcagaaa tatttgattg gtggtgcttc tgtactaacc
     4741 cttggcctat taggtgcttg tggtagcagt aatggcgaag caaataatga aacaggaacc
     4801 acaaaagtta cttggtatca ggttggagaa gaacccaaag attttgatga ggtcatgaca
     4861 aaagtcaacg aaaaattaaa ggaagaaatc aatgtagagt tggatatgcg gctgattccg
     4921 gacggggatt atcagcaaaa gcttggtgtg atgatcaatt caggagaaga atatgatatt
     4981 tgtttcgtca atggcacaga ttatgtgaat tatgggaaca aaggtgcttt cattagtctc
     5041 aacgatcatt tggataaaga gttgaaagat tatgcagctg aattgaatga aggatttatt
     5101 gaaggtgggg caattaatgg cgaaacttat ggattgccag tcaataacga tattgccaca
     5161 acggaatatt ggacctttaa taaagatttg gtagatcaat accaattgga tgtagagaat
     5221 gttgaaggtg tagaaacatt ggctccagta ttagaaaagt ttgcagaaaa aaatactgat
     5281 acgaatatta cgccaatcgg tatgacccgt accagtgtct gtattcctta tgacaatatt
     5341 atcggtggtg gtgtaccgct agcggttgca tttgaaggcg atacacaaac agttgttaat
     5401 acttatgaga ctccagaaat gatgacttat ttgaaggcta tgcatgagtt ttataaaaaa
     5461 ggatatattt tgaaagatgc agccactgtt acgacagatc catttcgaat tgatagtaaa
     5521 aactggtttt taggtcgtaa ctcaagtggt tatcaaccat tagcacaaaa aaaattagaa
     5581 gctctagcgg gacatggatt aattttaaaa ccagctggaa aagcttttaa aacgactgga
     5641 tttgcaagag tggcaatgca tgcggtatct gcttcaagta aacatccgga agcagccttg
     5701 aaattgttga attatgtgaa taccaatcaa gaagtagcgg atttaatggt ttatggaatt
     5761 gaaggaaaac actatgatcg caatgaagat ggttcgatta ctttaacaaa ctctgatgat
     5821 tattatcaag gcgcttgggc attggtaaat acttatctag tttcaaaaac ttcaccgatt
     5881 acagaagaaa gtaaaaaact agaagaagaa agtaaaaagt ttcaaaatga agcaccgatg
     5941 tctcctattt taggtttctc ttttgacgct tctgattttc gaacagaaat tgcaagtgta
     6001 caaaatatcg tgtcacaata tgaagtactt ttaagctcgg gaacagttga ccctgaacaa
     6061 tatgtaccag agttgttaga aaaactagaa aaagctggat tggataaaat tcaggcatct
     6121 gctcaagaac aatacgatga atggcgaaaa tctaacaaat aattttttac taaatgaaaa
     6181 gaatagacta agcagttagt ggggggattc aaatgaacga aaacaaatgg accaaaggat
     6241 ttaattgggt ttttcaattg ttgttactaa actttactta ttttatacta atttgtttag
     6301 gatttggaat tttaggtttt ttccctgcta cgatagcttt gattgctggc gttgtgaatc
     6361 gaaaaaaata tggcttgcaa gagtctgtga agttcatgag taaaatctat aagaaaaatt
     6421 ttgttagata taatctatat tgctggtcag caactttgtt gttggccggc aatattacta
     6481 cgatctggct ttgttggcag caaagcgcac cattgtttta tttattaagt acattattat
     6541 cggtaattac actgttccta gtctttgcaa tgttgaattg ggtcgtgatc aaaagtcttg
     6601 ggttgtggat gatgggagac cgactgattg actatttgct tttcacagca acgatgttgc
     6661 caacggtagt catgcaaggc ttggtgcttg gaatttattt ccgaatattg atgattttgc
     6721 ctgtgatttt tctgtttggc ggaacagctg taacggtaat attgattagt aaattaactg
     6781 aaagagcgtt agcaaagttg ccttgtcaga tacaatcgca ctaatttttt cacaaaaagg
     6841 agtatttctt tctatgaagt taactgataa acaagtagct aatatagcct ttatccagca
     6901 acttgagatt ccattgacac aaaaagatga agaacaaata gacttgattt ttactgacac
     6961 aaaggctaat gtgcgacaaa tcaagattac taaaaatgag cagcaacgaa tttgcttgtc
     7021 ttattcacat gaagacttgc tgtatcgagg attgtttatc tgccttccac gttttttagc
     7081 tcaaggagga gagatgccat acattgaaga aacctcgatc attgagacca gttattcatt
     7141 agatgcttct cgtaatggcg tgatgaataa agagactcta aaaaaattca tttcttactt
     7201 agcgttgatg gggtacaaca cattgtatat ttacacagaa gatacctatg aagtagaaga
     7261 ccttccatat tttggttacc ttcgcggagc gtatacaaaa gaagaagtga atgaaattgt
     7321 tgaatttgct tctggttttg gcatagaagt agttccatcg atccagaccc ttgctcactt
     7381 gacccaattt ttgaagtggt atgctcaaca agaactgatg gatgatcaaa atactctact
     7441 gatcggtgaa gaaaaggttt atgcggcaat cgaaaagatg attattgcct gcaaagaaat
     7501 gtatcagaca gagcgtattc atttgggaat ggatgaagcc tatcaagcag gtctgggacg
     7561 atatttaagc ctgtatgggt attgtgatcg gacaacttta atgattcaac atatggaccg
     7621 tgtgttatca attgttgata aatataagat gaaaccaatg atttggagtg atttcattta
     7681 taagctatta gatgaaaccg gtaaagatag gtattacaat cctgatttta aactcaaagc
     7741 attagcagct aaaggattac cagcaggatt aacctatgtt cattgggact atggttcaga
     7801 tgaagtttcc tcctatgaga aagtaattga taaccatttg aaattttgtg acattgatca
     7861 ttacgtttta gctagtggtg cccatatctg ggggagacta gccccgaatc atgggaaaac
     7921 agaagcaatt gtttctgcag ctgtaaaagc ttctaaaaat aaaggtgtac gttctgtgat
     7981 gttaactact tggggagatg aagggcagga aacagagcat tggcattcct taattggggc
     8041 attaaaatta gcagattatg tctattctga agaagagtgg aatgattttg aggaaatcta
     8101 cgatcgttta ttaggaacag gtagttatca attaatgtcc gaattacgat atttcgatga
     8161 agtggatacc attacaaata acaacttaca aatggcttcc gtgagtaaac tgctactttg
     8221 gcaagatccg ttagttggta tatatgactt tcatgtagcc gctcataaca aaattgccac
     8281 tagaacaatt ggtacttatt atcatgagtt agctcagaaa ttagatatga ataaaaattg
     8341 gaatccaaaa caaccaattt taacaactat tcgtcaacga tatatacttt tagctgaaat
     8401 tttagcacaa aaggcagaac taggcatcta tttacaacac tgctgtctgg tagaagacct
     8461 tgcaggatta atggaattag cgaatcggtg tgaagcacta gccaatcgag taaatgaatt
     8521 ggcatctatt catgaaataa tttggtatca aacatacaaa acctatggtt gggaagtatt
     8581 agaacaacga tatgctgcat tagctcatcg tctgaaaacc gttgcgcgtc gtattaaaaa
     8641 tcatcttcag gggcaagatg ccctagagga gcttttggaa gaacgattac cgttttgtca
     8701 atatcaagtg ccgcttgaaa tttctggctt taattatcgg caaagctcgg tgtcaggcta
     8761 caattaacga aggaatcttc ccgttgaacg gaccacttgc tcatctaatg ggaaagtggt
     8821 tcgttttcta ttcataagta gcttaccact aactctttta ttaagaagag aaaaaaagta
     8881 ggaagtgaga aaatatgtta tcggactatt atcaaaatct gtcagttata agtgtcaata
     8941 cagaaccatt acgtaattat tatattcctt atgcaagtaa agaagaagca aaacaagagt
     9001 tagaaaggga aaaaacgagc cagtttatcg atctcaatgg tacatgggat tttcagtatt
     9061 atccttctgt ccaacagtta ccggaaaatt tttttcaaga ggcctttact gaaagctatg
     9121 atagaatttc tgttcctgga gtttggcaaa cagagggatt tgacttacct cagtatatca
     9181 atgtatctta tccaattcct tttgatccgc cttatgtacc taatgatacc ccttgtggtg
     9241 tatatcggcg tcagtttcaa attgagcaaa cagatgcacg cttttactta aatctagaag
     9301 gagcagatag taattgtttt gtttggataa atagaaactt tgtaggctat gaccaagtga
     9361 gtcatagtac atctgaattt gatgtgacca agtatttaca ggttggggtt aatgaaattc
     9421 aaattctagt gatgaagtgg tgtgatggta cctactttga agatcaggat aagtggcgaa
     9481 tgagcggtct atttcgtcca gtgtatcttc ttcaacgacc aactatgcat ctgacaagtt
     9541 atcaactacg gacgttgact gatcctaaaa aaggaagcgg aacattaatg gtttcttttc
     9601 aacgatttac tcctattgaa gtatcgttac ctatttctta cgaattattc catcctgatg
     9661 gacgtctcat agcgaaaggg gagtgttact cggaacaaca aataaatttg gatgttgaag
     9721 attgcctttt ttggacagca gaaacgccta aattatatac attactttta acatgtaatg
     9781 gtgaatattt taaagaaaaa gttggctttc gagcactgac gatcaagaat cgtaagttat
     9841 tgctgaacgg aacacctatt aaattatatg gagtcaacta tcatgacgtg aatcagcaag
     9901 gcacgccagt gatgacccga gagcagttac gtgcagattt gttattaatg aaaaaattaa
     9961 atgtgaatac tgtacgaacg gcacattacc ctaaatcacc agatttttat gaattggcgg
    10021 atgagattgg tctgtatgta atcaatgaag cagatttgga gtgtcatggt gtggttaatc
    10081 tatatgatac tgaagcgaat tatcaactaa ttgctaatga tccgacattc gaaaagccga
    10141 ttatggaccg agtgatccgt tctattcttc cttatcaaaa tcgaagctct atcattatgt
    10201 ggtctatggg gaatgaatct ggttatggag taaattttga aaaagctcaa gctttagcac
    10261 ggaaattgga tgattcacgg ttgattcata atgaacgctc gattgaacca gttattgacc
    10321 aagtgaatga ttttagtaac ttggatgtta ttagtcaaat gtatccccca ctggaagatg
    10381 ttcatcgtca ttgtcaaaga agtgatactg aaaaaccttt ttttatgtgt gaatatagcc
    10441 acgctatggg caacggtcct ggagatctta aaacgtactt cgatttgatt caacagtatg
    10501 attcctttct tggcggttgt gtctgggagt ggactgatca tgcaatcaat agaggaactt
    10561 tagaaacgcc atcttattta tacggtggtg attttggtga aaaatatcac gacggcaatt
    10621 tttgcgtaga tggtttattg accccagatc ggcaattaac agtaggtgca ttggagtacc
    10681 gtaatattca ttcgcctatt caactgattg ctgtagatga ggagctgcaa gaagtaacct
    10741 tgagcaatat aactgctttt acagccggtt cagcatttaa cctttctctt gaatggtata
    10801 tagatggaaa aaaaacagtt tatgaagtaa tgaatccttt catacttgag cctggcaaaa
    10861 gttgttcatt gcccatcaca gtacctacaa cgattcatgg tgctcatacg gttgctgttt
    10921 cgctatctgt ttataaaaat gatgagcttt atggacagca acagctcttt cttaaaaaag
    10981 aaaaaatgag attgccaaga actgctcatc ataatgatgc accacaaatt tcagtaaaag
    11041 gcacagagct gataatcaaa ggagaatcct ttatttatat atatcaatta gcaaaagctg
    11101 cgttcacttc tgtaaagatc aatcaaaagg aacttttgga acgtcctact caattttcaa
    11161 tttggcgtgc accaacggat aatgatcgta acttagtaaa caaatggaaa gcagctggat
    11221 atgctgaaat gtctttagaa atcagaaaaa aagactggaa attcgtagat gatcatctcc
    11281 tgatcgaaac gtcttatcga ggagttattc caggattaca gccaattttt acaatgcaca
    11341 tacagttgaa aataaatggt gcaggcgtaa tcaaccaaaa agtatcagtg gagaaaaatc
    11401 cgatttttcc agatttccct cgctttggga tggactggcc gttgaatgat actttttcga
    11461 aggtttctta ttgtggctat gggccgtatg aaagttatcc tgataagcac tatgctgcga
    11521 tgtttggtat ttatgagatg gagattgagg aatttgatca gccatatatc aaaccacaag
    11581 aatatggtaa ccgctggcaa tgtgattggg tatcaatcaa aaatcatcaa ggatctacca
    11641 tgacggttta tggaaactct aatttttctg ctctgcctta tagtcaagct caattaaccg
    11701 aaaagtcaca ccattatgaa ttaataaaag aaaatagaac ttggttcaat ttaagttata
    11761 aacaaaatgg tatcggctca cacagttgcg gtccttattt agaagatcgt ttccgtttta
    11821 tggaagatac ttttgactgg aatatagtga ttactttcaa aggagaaaat agatgaaaga
    11881 aacaaagatc aatcaagtca aaaaaaaatt atctcgttat caagaagttg tttatcgaaa
    11941 ccattgctta aaatggtcaa aaaataagct gaatgttcgt tttaatggat tattttatcg
    12001 tttcgaacag ttagaagaag tctggaaacc ggtaacgaat ttccaatcat gtcctgtaca
    12061 gctcataaat gatccaaaag aaacatacga tttatgtata acacaccttt ataaccagca
    12121 tttgaaaaat gacggatttt atttaaaggt tactaatgac aatcaactta cgattgaatc
    12181 agcaaacctt cgagggtttc aatatgctat ggaagcctta ttagagagtt ttttttcggt
    12241 aggagatcaa ttattattac cggaattgat tctgaaacat gaaccatcag tgaaaattcg
    12301 aggaatcatt gaagggtttt atggtatccc ctggacacat gaaatgcgcc tctctctttt
    12361 ttcatatatg aaagataacc aattgaatac ttttatgtat gcccctaaag atgatgaatt
    12421 attacgtaaa aaatggcgtg aactctacga tgcgcaagaa ttagacaaat ttaaggagct
    12481 tttatctgct gctgaggcta gcaatatcga tttttggtac ttaattagtc ctggaaatga
    12541 tattgatatt acgtgtgaag aagacattca agttcttctg aaaaagttag aacaactgat
    12601 tgagcttggc gtatttcaat ttggtctatt aatggatgat attgactatc aattaaaagg
    12661 tgctgctaaa cgccgttttc gagagccagc attcgctcat gcctatttag tgaatcgagt
    12721 agaggaatat cttagcactc ggttgtccaa tcatgaatta gtcatttgtc ctacagaata
    12781 tgataatcgt catggttctc gctatttagc aacgttaagt caagaaatac cagaacaatt
    12841 accgttcttt tggactggcc caagcacgtt agcggcgtca atttctacag aagagctgca
    12901 ggaaatggct tctgtctatc aacggccgat gctgatttgg gataatattc cggtaaatga
    12961 ttatttagag gataaagaac tattgttcat gagtccatat gagaatcgaa caccgaatct
    13021 ttctaaggag agataccagg ttacaggagt agtttcgaat ccaatggctc aattagaagc
    13081 ttcaaagttt acgatcaata gtatggctaa ttacttatgg aactgtgagc gttttgatcc
    13141 tttggaaact tggacgtcag tcgttgaaaa agtagttgga agtaaactac aaccagctta
    13201 tcttacctta accaatgctt ttccaaatca ttacacaagc agtctgcttt cagatgaaga
    13261 attactgcta gccaaagacc cagaatgggt cacaaaagaa atggctgctt tagtccaagc
    13321 agtaaaatgg atccagcaag aacaacatac atctagattg agaacagaat tggagccttg
    13381 gttacaagca atcacagaaa gttggacttt ctggcaagaa tggcaattaa aaaaagatcc
    13441 aaaagaagca gaagaatggt tggctaagaa aaaaacacac cgcataggac gtgatttagt
    13501 aactgcccat ttagagcaaa ttatcaaaag ttagatatct taaaaaataa aaagcaagaa
    13561 aaaggagaac aaaatggtca agagattaat tagtgcaaac tacagtgatg tcaagaaaat
    13621 gacgtcaaaa gagttgaagc aatccatcaa agcgagtgaa ggacgggtga ttgtttgtga
    13681 aacggttgct aatactcttc cacaatctgg agaaattacg aatgcagaag ttgcgtcagc
    13741 atttggtgca gatttgattc ttttaaatgg tttcgattgt tatcgtcctg cagtttttgg
    13801 actaccaaat gtgacgattg agaaggtttt tgatctacag caaacgattg aaaacccgat
    13861 tcctaaatta aaagaactag tcggtcgtcc tgtgggaatt aatttagaac ccattgcccc
    13921 taaaacaaat atgatgagtg agaaagtaga aatcagccaa ggaagagcaa gctctgttga
    13981 aacgatacaa aaagcagaag aactaggagt cgattttatt tgctttaccg gtaatccagg
    14041 cactggagta accaatttag aaattactaa atccgtaaaa atggcaaaaa agtatttttc
    14101 gggattgatt attgctggga aaatgcatag cgccggctca gaagagccag ttgtgaataa
    14161 agaggcgatt atttcttatg cggaagcagg cgcagatatt ttactagttc cttcagtagg
    14221 gtctatccca ggctttttag agcaagacct aattgaagcg gttcggttgg caaaaaaata
    14281 tgatttgtta acgatgtctg caatcggtac tagtcaggaa agtgcccgac cagaaacatt
    14341 gcggcaatta gccattatga ataaaagttg tggtgttgat ttacaacata ttggagatgc
    14401 tggatacggg ggattggcac cagcagaaaa tattttcgaa acctcggttg caattagagg
    14461 aatgcgacat accatcaact gcgttagccg ctcgatcaat cgctaacaaa attaaataaa
    14521 aaatggttaa attgattatt taagtgggaa catacttgag atatcagcta acttctgtca
    14581 ctttaaaaaa gggactgtga cagaagtgaa aatagacaaa aaatatccga acaagagact
    14641 aggatagcag aaaaactatc gttttgcaac gaggaccaac tggaccgtag gagcaattct
    14701 cttattgttc ggatatttcg cttgttcaag gacttatgtc tgtagtgccc ttttttggta
    14761 ggaaaaatgg tagggaacca tatcattttt aatgaaaatc aagcatttca aaagttgaaa
    14821 agtaagcgcc ccatagaaca gtacctgtac gtcaaataac ccgacctata gaatagaatc
    14881 gggaatgttt ggcgttttta gttacgagaa aaatgttgtt gtacatcctt gttccaaggc
    14941 aacagttgat ctaaagtttc tgctgaaagt acgggaagat ttggtatctt atcaaataga
    15001 aactctagat actttacagg attcaatccg ttaagttctg ctgttttata tacactcaga
    15061 atgattcctg aagttcgtgc tccttcaaga cttgtggaat gcaaccaatt tttccgtcct
    15121 atcaccagct ctttgatatt tcgctccgca cgattatttg tgagttctaa acgaccatct
    15181 tcaaaaatag gttcaaaacc acttcgtagt ttacacgcat attgaacggc tgcatccaac
    15241 ttggattttg caacaggatc tatcgttgcc atccactcat aaaaagcaat aaataatgga
    15301 cgcagttctt gttgccgaca gcttaatcgc ttctcaggag aaaagtcttt ccatttcttt
    15361 tctaggacaa accatttatc caattgtttg actgcttgag ctgcgggaat atccgtgttt
    15421 ttctttcctt ttggaattgc ttcgaaaaat ttccgccgaa catgcgcgaa acaatagaca
    15481 agtcgtacac tttccacggc attatacccg ctatagccgt cacagtgtaa ataccctgta
    15541 aactccttga gaaaagtttt cggaacatct ccagcacgac tttcgtcgtg gtgataataa
    15601 acgatgggat gctgactgtc ttttcctgta caaaactgcc agtaataggt atctgttttg
    15661 gcactttcaa tcacacgata acttgtttca tccccgtgta gaatctcttc ttgattaaga
    15721 tagactctta atcgttctcc taaagggtct aacgcgtttt gcactgcttt aatatgccaa
    15781 ttggtgatat tatctctcga aatatccaac ccatgtgttt gtttccaata gttctcttgc
    15841 cgataggcag gaactttctg accaaatttc atccggatcg tttccgccac taaactattg
    15901 gaacctaagc tattagaaat caaaggttta ggaacgatcg cttttttaaa agaagaaagt
    15961 ccttcttttt cgcagctttt acaacaatag gtatgttgat aatgggtgag acaatccaac
    16021 atagcctgat ggaaacgaat ttcttctcgt acttttgtcc gtccgatatc tttcatctgt
    16081 gaaccgcaat gttcacaaaa ttgttcttcc aaaggaagga gatgttcttt ctctgttata
    16141 g
//
LOCUS       DAPBAF010000056        15612 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.056, whole genome shotgun sequence.
ACCESSION   DAPBAF010000056 DAPBAF010000000
VERSION     DAPBAF010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15612)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15612)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15612
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.056"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(<1..237)
                     /locus_tag="RD451_002348"
     CDS             complement(<1..237)
                     /locus_tag="RD451_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HDT7567564.1"
                     /translation="MTYTHLTPNELVMIEAYFHQETPVAIVAKQLKRGRQTIYNVYNF
                     LKCGGTALEYFEQYKENKRRCGRTEIIFPAEEKEY"
     gene            576..1085
                     /locus_tag="RD451_002349"
     CDS             576..1085
                     /locus_tag="RD451_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDT7567565.1"
                     /translation="MVQGIERGVYVVDKIQFNQVIEEFIKVNNLMTHIQKRPIRITND
                     LKLSTSMIHLIDVIGNYPETSITELADRLGVTKGAVSQQIPTLEKMNLISISQKKGNK
                     KTKLVSLTKYGRKVYESHNYLHEELYSSINEALESFSPDQISTIKQILEKVSYTINEY
                     QVSLTRKED"
     gene            1178..2340
                     /locus_tag="RD451_002350"
     CDS             join(1178..1454,1454..2340)
                     /locus_tag="RD451_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HDT7567566.1"
                     /translation="MSRRQRRTYSKEFKQQVVDLYLAGKPRAEIIRDYELTTSAFDKW
                     VKQAQTTGSFQEKDNLTPEQVELIALRKKNKQLEMENDILKQAALILGPKRQVIDTNK
                     HKYSISAMCKVLNISCQTYYYQAKPVEDESELEELVQEEFIRNRKAYGTRKLKQCLAN
                     LGLQVSQRRIGRMMKQRGLRSTYTLAHFKFHSSTCNEAKTANILDGTFLQEKSLEAIV
                     TDLTYVRVGKKWQYICLILDLFNREIIGYSCGEKKDATLVKEAFAKIPYSLNNVQLFH
                     TDRGKEFDNQTIDEILWAFNITRSLSKKGCPYDNAVAESTYKSVKVEFVHQYRFETLA
                     NLRLELFDYVHWWNTIRLHGTLGYETPISFRQQRLAQRILDNELGCDTGGEAP"
     gene            2620..3600
                     /locus_tag="RD451_002351"
     CDS             2620..3600
                     /locus_tag="RD451_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDT7567567.1"
                     /translation="MKKIGIREVAKEANVSPTTVSRVLNDRGYLSEETKRKVFDAMKK
                     LEYYPNELARALFKNETYTVGLIFPTITNPFHAELIQDIEFELSSRGYKVLLCNSLNN
                     PTKEKEYLTMLRKNQVDGIIVGTHNKDIADYDIPGLPIVAIDRSLGENTVTVSCDNYR
                     GGELATQLLVNHGCQNILCIRGDSKIKLPANSRTLAYKDVLNKFMLEPLVLEVPFVKE
                     INEKNEIIKTYLETHPNIDGVFAGDDLLASLAINNLGSSGKRVPKEVKVIGFDGAQQT
                     LIYNPELSTIQQPIDQISKVAVKKLLNMIKGEKETDELSLPVKLIKKNTA"
     gene            3722..5140
                     /locus_tag="RD451_002352"
     CDS             3722..5140
                     /locus_tag="RD451_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HDT7567568.1"
                     /translation="MEKLLIKSNNHQLYYQPKDVWVGDVMPYGKEGKFFIYHQRDTRN
                     PVPFGEPFGWALATTKDFVHFEDFGESLLRGDDNERDQFIYAGSVFEANGKVHAFYTG
                     YNREFLAQGKTSQVLLHAESDDFVHWEKSETALELEPQEGYDIRNWRDPFVVWDDEKE
                     EYLLILGARKGQDKHLQTGRLVEFTSKDLTNWEFKGDFWAPGLYTMFEMPELFKIGDW
                     WYLVYSEYSDGNKILYRMSQSLEGPWIKPKDEAFDGRAYYAGRTAYDGKRRVLFGWVP
                     TKDQENDKNNYLWGGTLVPHEVYQKEDFSLGVKPIDEVWNAFINLHDIADVEIETADT
                     REEVTLVKNSGTLFNLETTISFDENLSDFSLRLYKNLETDESYEYRFNLDEGRLTFDK
                     NPCYPWFQYMDKGLIRPISLKPNQSYKLKVIVDDNIMTLYIDGIALNARVHGCFGQAI
                     TITATNGSMTAINTKFSNEIKK"
     gene            5211..6680
                     /locus_tag="RD451_002353"
     CDS             5211..6680
                     /locus_tag="RD451_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDT7567569.1"
                     /translation="MDYKKIAEDVLENVGGKENISSATHCITRLRLILKDKSKANMEM
                     LEEIEGAKGVLFNSGQLQVIFGTGIIEKVYKEFVELTGAKEVSVSEMKDEGVNNSGNR
                     LQRAFKVFSDIFIPIIPAFIGAAMVLGIRSLITTPGMFGMDGSFADHNVFLNDLSKFL
                     GIIATTFDYLPVLVMYSATKRFGGNPILGLLVGFVMIHPGLANRNDFVMGTIKPDYWH
                     LFGLSIPAVAFQGGVFPAILTSWFLAKVEKITNKYSPQVLAYILVPTVTIVLANFALF
                     LVFGPLGNFIGNVLGGIIDFLYMKMGAFGAFVFAGALQPLVVTGTQHAIQGIEANLVA
                     TTGFNYIQPIWSVSIIAQGGGCIGMYLLFKKKSKDRDIAISSFIPTLVGITEPAIFAV
                     NLKYSIVPFVCSFIGAGFGGAFMKIFDVKAIGQGLTVLPGLTIANPVLPYIFGNLIAF
                     ILPIIFILAYDKYKVFIPEAKHRKFAEKTDSKKLPVQVK"
     gene            6690..7157
                     /locus_tag="RD451_002354"
     CDS             6690..7157
                     /locus_tag="RD451_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDT7567570.1"
                     /translation="MLNFFRKNEISVVAPATGVFEKLEKLSDPVFSKGMMGQGFAIDA
                     KNETIVSPIDGFVSSIFPTKHALGIKTKSGIEILVHVGIDTVELNGEGFDIKVQEGQK
                     VKAGDILMTINFVVFEKNHKTKDVIVVFPDYQDEIFIPKLEEVKQGQELFVLG"
     gene            7193..8065
                     /locus_tag="RD451_002355"
     CDS             7193..8065
                     /locus_tag="RD451_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HDT7567571.1"
                     /translation="MVFGAIEAGGTKFVCAIGDKDLNIFEKVSFPTTTPKETMNLVLD
                     FFNHHKDDLEGIGVGSFGPIDIHCESKTYGFITSTPKLAWQDFDFIGSLKKQLNIPTA
                     WTTDVNASCYGEYVSGNGRGLSSVVYYTVGTGIGGGAIQNGNFIEGFSHPEMGHMLVK
                     RHNKDNFSGTCPFHGDCLEGLAAGPAIERRSGKKGQEVTENDVTWEIEAYYIAQCAYN
                     TTLMLSPDVIIFGGGVMKQKHLKKKVQDKFIELINGYVAIPDVDNYIMTPKLLDNSGI
                     VGCLALARDVKEKS"
     gene            8147..10681
                     /locus_tag="RD451_002356"
     CDS             8147..10681
                     /locus_tag="RD451_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDT7567572.1"
                     /translation="MKKKMKDEVLEYIKNNLKYYDFSAQDIAMKFCIKRNVASHYLNQ
                     LFSDGKLLKNDSVRPVMFKYNQQKPKDCFSKFIGADISLKSTIDKCKATVMYPPNGLP
                     LIIKGNSGVGKSFLASLIYQYALDRKVIHNDAKFVVVNCADYANNPELLSAVLFGYKK
                     GAFTGAEKDTAGMLSSANGGYLFLDEVHNLSAENQEKLFLLMDSQKYRKLGESVQWEY
                     ANVRLILATTEDKNTSLLATFRRRIPAEITLPDYNNRSTSEKIQLLFEFLKDEAITID
                     SKIFCSIELFTDLLSKTFEGNVGELRNEIKLLCAEGYLGNKRKSSIYLGDKLDSGFWI
                     DPEISIDLKKMFLKSLSEIDLIELFQNHISIEESMSQLRDRILKECAGSSEYNYLESD
                     EFIALRNYVVNKISPIIDSTGLCLLDEFLADISLFIMFIDVIEETSRNFLLSKFRKFR
                     MKNDKQKLLANEIWSSLEVEESKQELLLKWILFLVKKFYVKIPETHCLIVMHGKITAS
                     AIARETNKLLNTYVYEAFDMPIEGETSDLINLINNFCKSIDTTNGLILLVDMGSLEQM
                     YEKIESNVIGDLVILNNVSTALAIECGIQVCQKKPISHFYQMDFDSFQVKVQYYKGLS
                     QKKNVIVSCLSGEGISEKVKDILKRYLDNQVEILIFDFNALKKIAKEKDTMIFKNTIC
                     VLSTTEFYIQGIDCLNLENLINGNQTLEKLNKYMDSDSCEFCLNELVKLFTIEGASTK
                     LRFLDSKKVFNEIEKVLYLYEKYYDVKIPSFLRINLFLHLSGMIERIMIGDGITNEHL
                     KEGAQLFDTFLNVSKDFFSEIKDIYCIEIPKGEYELIYTIFEQTIF"
     gene            10837..11610
                     /locus_tag="RD451_002357"
     CDS             10837..11610
                     /locus_tag="RD451_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDT7567573.1"
                     /translation="MAFWQTFLVVLYGFFINWDKEGPKIGTSQPVVAGFLTGLIMGDI
                     QTGLYIGGTLQLMTLGITSFGGASVPDYQTAALIGTYLAISTNQDASIGITLAIPVAM
                     LIVQLDVLKWSTNIFFQQKAEKFAQKEDYQKLEWMQYLASINTSFVSGIPVLLTVILG
                     PTLVGSAINYIPEWVTGGLKVAGGLLPAVGIGMLLKYLPTKDYFAYLLVGFVLAVYFQ
                     IPILGISLLGAAIALIVYKNRSNNTQVAPAATGGFDEDE"
     gene            11603..12394
                     /locus_tag="RD451_002358"
     CDS             11603..12394
                     /locus_tag="RD451_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDT7567574.1"
                     /translation="MNKKLTKIDKQVIFRWILNGATSLNYEKMEGLGYAYSMLPFIKD
                     TYKDDPEGMKQSVLAHLQFFNTTPYTAPYIIGMNVGIEKEEKNKSLEAVSALKTGLMG
                     PLAGIGDSVFVVIPWTIFGAIAANMALEGSFVGIILWILASILLRITAYPLYLAGKES
                     GASLLTQIETKLKSITDAVSILGLMVVGALIATVVKVNVGFEFKQGDLTMTGNEIFDQ
                     VMPGLLPACVVAIVYYLLGRKVKPVYVILLILVVSIALRALNILK"
     gene            12404..12895
                     /locus_tag="RD451_002359"
     CDS             12404..12895
                     /locus_tag="RD451_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDT7567575.1"
                     /translation="MDEKMKGIIHVRIDDRMIHGQVATQWTNQLSANRIMVINNEVAN
                     DDVKKAVVRLAAPPNVRTSIITREVAVKNILSGKYEGQKVLIVAVSPIDVKFLIDNGL
                     PITSVNVGNLSRRNGTERIRPTINITEEEREAFKELISDGVEVTVIQTPRDSKEFLKD
                     FIY"
     gene            12913..13323
                     /locus_tag="RD451_002360"
     CDS             12913..13323
                     /locus_tag="RD451_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDT7567576.1"
                     /translation="MEFIITSHGNIAIGFVDTLKMFFGDNLNCHVVTLGDAGIEEFRE
                     NIEKIVSQVKNQEVMVFADLIGGTPFNEFAKRSEVFQNGFQLLGGMNLGILIEAVNLR
                     LQGKKSDDIIENLRNMNTIACLADMQRHTNEEDE"
     gene            13327..14727
                     /locus_tag="RD451_002361"
     CDS             13327..14727
                     /locus_tag="RD451_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-fructofuranosidase"
                     /protein_id="HDT7567577.1"
                     /translation="MQKIFYKPKDFWFGDCMPFYKDGTFYLFHQRDTRNPKPLTDPFG
                     WSLVTTTDFVKFEEYGEVIHRGGNDDIDQYIYAGSIVQGINEYLALYTGHNRKAKLDG
                     KTSEVLMIASSKDLIHWKKDGEAAKLVPQEGYDKNDWRDPFAIFDQDHGKYVLILGAR
                     KPASKKKPTGRLVYFESEDLKDWNFKGDYWANNEFNMIEMPDIFEIDGTWYLLFSEYC
                     EDKKTKYRVGAGLFSDWKSPVDEAFDGKAYYAARTVGTNETGRFLTGWVATKEGENDQ
                     NNWDWGGALVPHQIIQKTDKTLGVKLPEKIIENFKEITPFSSFKLEKEFGKKERVIVP
                     KIEDYFLFETTLTITSLTKEFALKLFVDSDTQEGYEFRISLINNQLTFGKTPNYPWPQ
                     MFDKGLQRPLFLEIGKEYELKLIVDDTIAVLYIDNVALSTRMYDKVGTALSMTVTEGA
                     IKVDKLDYSINYECGF"
     gene            14750..15124
                     /locus_tag="RD451_002362"
     CDS             14750..15124
                     /locus_tag="RD451_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDT7567578.1"
                     /translation="MKLNGLQHIGIPTKDFGASKIFYESLGFSLINEEMNVGSKVGFF
                     ELNGTIIEIWEDKTTECRGAIDHLALDTDDIDEVFNSIQDLGYELLDKNIMELPFWEN
                     GIRYFNFYGPNHEIIEISQMKK"
BASE COUNT         5392 a         2209 c         3118 g         4893 t
ORIGIN      
        1 gtattctttt tcctcagcag gaaaaatgat ttcggttctc ccacaacgtc gcttattttc
       61 tttgtattgt tcaaagtatt caagtgctgt tccaccacat ttgagaaagt tatagacatt
      121 gtaaattgtt tggcgtccac gtttaagctg cttcgcaacg atagcaaccg gagtttcttg
      181 atgaaaatat gcttctatca ttacaagctc gtttggtgta agatgggtat aagtcattta
      241 tgttcactct ccttgtatgc tttagcgggt attacaattt gagtgtaaca taaatggttt
      301 ttttatttgt ctcgcttaat tatacaaacg gcgtgataaa aaacgagaaa tgaattatag
      361 gtttagacct ttatcatttc tcgttttatt ttattgtatc aaggctctat cataagtggt
      421 aaaatctact tttaaatcac atgtaatcat tgataagtcc agtgttttag cggataatca
      481 gctttttatt tattttttct tataaatttg ataaatagaa attagtatag ccctaaacaa
      541 attatttgtg ttttattgtt tagggctata ctatattggt acaaggaata gaaagaggtg
      601 tttatgtggt tgataaaatt cagtttaatc aagttataga agaattcatc aaagtaaata
      661 atttaatgac ccatattcaa aaacgaccaa tcagaataac taatgatcta aaactcagta
      721 cgagtatgat tcatttgatt gatgtgattg gaaattatcc tgaaactagt attacggaat
      781 tagctgatcg attaggcgtt accaaaggag ctgtatccca acagattccc actttagaga
      841 aaatgaatct tataagcatt tctcaaaaaa aaggaaataa gaaaactaaa cttgtatcgt
      901 taacaaaata tggtcgaaag gtgtacgaat cacataatta tttacatgaa gagctttata
      961 gctcaataaa tgaagcgtta gaatcattct caccagacca aatttcaacc attaaacaga
     1021 ttctagaaaa agtatcttat acaatcaatg aatatcaagt aagtctgaca agaaaggaag
     1081 attgacatga aaaaaatgat ttttgaatcg gctacactag actagacaga aaaaataagg
     1141 tgtgtaaaat aaatgaaaac acactggagg aatttttatg tcaagacgtc aacgtagaac
     1201 ctattcaaaa gaattcaaac aacaagtcgt cgatctttat ctcgcaggaa agccccgagc
     1261 tgaaatcatt cgagattatg agctgactac ctcggccttt gataagtggg tcaagcaagc
     1321 gcaaactact ggctcgtttc aggaaaaaga taacttgacc cctgaacaag tagaactaat
     1381 tgcattacga aagaaaaata aacagcttga aatggagaat gacattttaa agcaagcggc
     1441 gctgatattg ggacgaaaag acaagtaatt gataccaata agcacaaata ctcaatatca
     1501 gcgatgtgta aagtgttaaa catctcttgc caaacctatt attatcaagc caaaccagtt
     1561 gaagatgaat cagaactgga agaactcgtt caagaagaat ttattcgcaa tcgaaaagct
     1621 tatggtacca ggaagctgaa gcagtgcttg gccaatctag gtcttcaagt gagtcaacgc
     1681 agaatcggcc gtatgatgaa acagcgtggc ttgcgttcaa catacacatt ggctcatttc
     1741 aaattccatt cttctacttg taacgaagcc aagaccgcca atattctaga cggaaccttc
     1801 ctacaggaaa agtcattaga agcgattgta accgacctta cctatgttcg tgttgggaag
     1861 aaatggcagt atatctgcct gattcttgat ttgtttaatc gagaaatcat cggctattca
     1921 tgcggggaga agaaagatgc gacgttagtc aaggaagctt ttgcaaagat tccgtactcg
     1981 ttgaataatg tacaactttt tcacacggat cgtggaaaag aattcgataa ccagacgatt
     2041 gacgaaattt tatgggcctt taatatcacg cgttccttaa gcaaaaaagg ctgcccctat
     2101 gataacgccg ttgcagaatc cacctataaa tctgtcaaag tagaattcgt tcatcaatac
     2161 cgctttgaga cattggctaa tttgcgatta gagctatttg attacgtcca ttggtggaat
     2221 accatccggc tgcacggcac gttaggctat gagacaccga tcagttttcg acagcagaga
     2281 ttggcgcagc gaatccttga taatgagctc ggatgtgata ccggtggcga ggcaccttaa
     2341 ttatttgaat gagcttctgc cttagagaat cagattcgag gaggctcgtt gtcaagggca
     2401 gtcggaacac cagcagcaag cttacgcaat accttataat ttttgtcaaa aaaagtgttg
     2461 ccattccaca tatatcttta aacagctatt gccagataaa aataaatgat attatatata
     2521 taaatactta tccgaaaagg ggaatgagag agtcaaggtt cttggaatgt cgaatagtcg
     2581 agtaggtaga ttttctatct acaaccttgt tgtttaaaaa tgaaaaaaat tggaattaga
     2641 gaagttgcga aagaggcaaa tgtttctcct acgactgtgt cgagggtatt gaatgatcgt
     2701 ggatatttga gtgaggaaac aaaaagaaaa gtttttgatg ccatgaaaaa attagaatac
     2761 tatcctaatg aactggcgag agcacttttt aaaaacgaaa catataccgt aggtttgatt
     2821 tttcctacaa ttactaatcc atttcacgct gagttaattc aagatatcga gttcgagctt
     2881 tccagcaggg gatataaagt gttgctgtgc aatagcttaa acaatccaac aaaagaaaaa
     2941 gagtacttga cgatgttgag aaagaatcag gttgatggaa ttatagtagg aacgcacaat
     3001 aaagatattg cggattatga tattccaggg ctacctattg tagcgattga tagaagtctt
     3061 ggtgaaaata cagttacagt atcttgtgat aattacaggg gtggggaatt agctactcaa
     3121 ctacttgtaa atcatggctg tcagaatata ctgtgtattc ggggagatag taagataaag
     3181 ctacccgcga atagtaggac tttagcatat aaagatgttt tgaataaatt catgctggaa
     3241 ccgttagtcc tagaagtacc atttgtaaaa gaaatcaatg aaaaaaatga aataattaag
     3301 acatatctgg aaactcatcc aaatattgac ggggtttttg caggagatga tttattggct
     3361 tctttggcga ttaacaactt aggaagttcg ggcaaaagag ttccaaaaga ggttaaagtg
     3421 attggatttg atggagctca acaaacattg atttataatc cagaattatc aactattcaa
     3481 cagcctatag atcaaatatc taaagtagca gtaaaaaaat tattgaatat gattaagggc
     3541 gaaaaggaga cggatgaact ttcacttcca gtaaagctca taaaaaaaaa tacagcataa
     3601 gttaaatcgg cgaaaaattc cttcgtcgat ttaaaaatat ttttatgaaa cgggttgaca
     3661 tatgaaacgg gttgacatat attagttgtg aagataaaaa ccttttcact ggaggaagaa
     3721 aatggagaaa ttattaatta aaagcaataa tcatcaactt tactaccaac ctaaggatgt
     3781 ttgggtcgga gatgttatgc cttacgggaa agaaggaaaa ttctttattt atcatcaacg
     3841 tgatactaga aatccagttc cttttggaga accgtttggc tgggctttag caactacgaa
     3901 agattttgtt cattttgaag actttgggga atctctttta agaggggatg acaatgagag
     3961 agaccagttt atctacgctg gttctgtatt tgaggcaaat ggaaaggttc acgcatttta
     4021 tacagggtat aatcgtgaat tcttagcgca gggaaagaca tctcaagtgt tgcttcatgc
     4081 tgagagtgat gattttgttc attgggaaaa atcagaaaca gcattggagt tagaaccaca
     4141 agaagggtat gatattcgaa actggagaga tccatttgtc gtttgggatg atgaaaaaga
     4201 agaatatttg ctaattttag gggcgcgaaa gggtcaggat aaacatctac aaaccggacg
     4261 tttagtggaa tttacatcaa aagatttaac taattgggaa ttcaaaggtg atttttgggc
     4321 tccgggattg tataccatgt ttgaaatgcc agaacttttc aagattggtg actggtggta
     4381 tcttgtctat tcagaatact cagatggaaa taaaatactc tatcgaatga gtcaaagttt
     4441 ggaaggtcct tggattaagc ctaaagatga agcttttgat ggacgggctt attatgcagg
     4501 tagaacagct tatgatggaa aacgtcgagt cctatttgga tgggtaccaa caaaagatca
     4561 agaaaatgat aaaaacaatt atttatgggg aggtactttg gttcctcatg aagtctatca
     4621 aaaagaggat ttttcacttg gggtaaaacc catagacgaa gtgtggaatg cattcataaa
     4681 tttacatgat attgccgatg tagagataga aacagcagac acaagagaag aagtaacgct
     4741 tgtcaaaaat agtggaactt tgtttaattt agaaacaaca atttcatttg atgagaatct
     4801 tagtgacttt tcactgagat tatataaaaa ccttgagaca gatgaatctt acgaatatcg
     4861 cttcaattta gatgaggggc gtcttacatt tgataaaaac ccttgttacc cttggtttca
     4921 atatatggat aaaggactta ttagacctat atctttaaag cctaaccaat cttataaact
     4981 aaaagtgatt gttgatgaca atataatgac actttatatt gatggaatcg ctcttaacgc
     5041 tcgtgtacat ggttgttttg gtcaagcaat tactattaca gcaacaaatg gatcaatgac
     5101 tgcaataaat accaagtttt caaatgaaat aaagaaataa taaacgtcaa tcatgtggca
     5161 ggtctgaaaa tcaaacatga cctgtcacat ttaaaaggga ggataaatga atggactaca
     5221 aaaaaattgc cgaagatgta ttggaaaacg ttggaggaaa agagaatatc tcaagcgcta
     5281 cacactgcat tactcgttta cgtttaattc ttaaagacaa aagcaaagcg aatatggaaa
     5341 tgcttgagga aatagaaggt gcaaaaggtg ttcttttcaa tagtggacag ttacaagtaa
     5401 ttttcggaac aggtataatt gaaaaggttt acaaagagtt cgttgaattg acaggagcta
     5461 aggaagtatc cgtttctgaa atgaaagacg aaggagtcaa taattcagga aatagacttc
     5521 aacgagcttt taaagttttc tcggatatct ttattccgat cattccagct tttattgggg
     5581 cagcaatggt tttaggaatt cgttcgttga ttaccactcc tggaatgttt ggaatggatg
     5641 gctcattcgc tgatcacaat gtattcctaa atgatttatc caaatttctg ggtattattg
     5701 caaccacatt tgattattta ccagttttag ttatgtattc tgcaacaaaa cgttttggcg
     5761 gaaaccctat tttaggatta cttgtaggat ttgttatgat tcatccagga ctagccaatc
     5821 ggaatgattt cgtcatggga actataaagc ctgattattg gcatttattt ggattaagca
     5881 ttccagcagt tgcgtttcaa gggggtgttt ttccagcaat tttgacttct tggtttttag
     5941 caaaagttga gaaaattaca aataaatatt ctcctcaagt acttgcttac attttagtcc
     6001 caactgtgac aattgttctt gccaactttg cactattttt agtgtttggt ccattgggga
     6061 attttatcgg taatgtttta ggtggaatca ttgatttcct atatatgaag atgggtgcct
     6121 ttggtgcttt tgtttttgca ggcgcgttac aaccattagt tgtaacagga acacaacatg
     6181 ctattcaagg tattgaggca aacttagtcg caacaactgg attcaattat atccaaccta
     6241 tttggtcagt ttcaattatt gcccaaggtg gcggttgtat tggtatgtat ttactcttta
     6301 agaaaaaatc taaagataga gatattgcga tttcaagctt tattccaaca ctggtaggta
     6361 ttactgaacc ggctatcttt gctgttaatt tgaaatattc aatcgttcct tttgtttgct
     6421 cgtttattgg tgctggtttt ggtggagcat ttatgaaaat ttttgatgta aaagccattg
     6481 gacaaggatt gactgtattg ccaggtctga ctattgctaa tccagttctt ccttatatat
     6541 ttggtaatct catagcattc attttaccaa tcatttttat tctcgcttat gataaatata
     6601 aagtgtttat ccctgaagct aaacaccgta aatttgcaga aaaaactgac tcaaaaaaat
     6661 tgccagttca agtaaagtga gatgagagca tgttaaattt ttttagaaaa aatgaaataa
     6721 gcgttgtagc acctgcaacc ggtgtttttg aaaaactgga gaaattaagt gatccagtct
     6781 tttcaaaagg aatgatggga caaggatttg caattgatgc aaaaaacgaa acgattgtat
     6841 ctccaatcga tggttttgtt tcaagtattt ttcctacaaa acatgcctta ggaataaaaa
     6901 caaaatcagg aattgagata cttgttcatg taggaataga tacagttgag ctaaatggtg
     6961 agggatttga tattaaagtt caagaaggac aaaaagttaa ggctggggat attcttatga
     7021 ccattaattt tgtagttttt gaaaagaatc acaagactaa agatgtcatt gttgtttttc
     7081 cagactacca agacgaaatt ttcattccga aacttgaaga agtaaaacaa ggacaagaat
     7141 tgtttgttct tggctaatga taagtaatta ataatagaat cgaggaaaat gtatggtttt
     7201 tggggctatt gaagctggtg gaacaaaatt tgtttgtgcc attggagata aagatttgaa
     7261 catatttgaa aaagtcagct ttcccacgac tacacccaaa gaaacaatga atttagtttt
     7321 agattttttt aatcatcata aagatgattt agaaggtatc ggagtgggat cgttcggtcc
     7381 tattgatatt cattgtgaat ctaaaacgta tggcttcatt acatcaacgc caaaacttgc
     7441 ttggcaggat tttgatttta ttggaagttt aaaaaagcaa cttaatattc caactgcttg
     7501 gacgactgat gtaaatgcct cttgctatgg tgaatatgtt tctggaaatg gcagaggcct
     7561 ttcaagtgtt gtttactata ccgtaggaac gggcatagga ggtggcgcta tccaaaacgg
     7621 aaacttcatt gaaggtttta gtcatccaga aatgggacat atgcttgtaa aacgacacaa
     7681 taaagacaac ttttctggga catgtccatt ccacggagac tgtttagagg gcttagctgc
     7741 tggtccggca atcgaaagaa gatcagggaa aaagggacaa gaagtgactg aaaatgacgt
     7801 tacttgggaa atagaagctt attacattgc tcagtgtgca tataatacaa cattgatgtt
     7861 atcacctgat gtcattatat ttggtggcgg agtaatgaaa caaaaacact taaaaaagaa
     7921 agtacaagat aagtttattg agttgatcaa cggatatgtc gctattcccg atgttgacaa
     7981 ttatattatg acaccaaaat tgttagataa ttctggtatt gtaggttgtt tagctttagc
     8041 aagagacgtt aaagaaaaat cttaatttgg aaaaaagatc gtctcgacta tttgtttggt
     8101 tgatgcgatc ttttttttca attagtaatt gaagggacgc ctaaaagtga aaaaaaaaat
     8161 gaaagatgaa gtattagagt atatcaaaaa taatttaaag tattacgatt tttctgctca
     8221 agatattgca atgaaatttt gtattaaaag aaatgtcgct tcccactatt tgaatcagtt
     8281 attttcagat ggaaaattac taaagaatga ttctgttaga ccagtaatgt tcaagtataa
     8341 tcaacaaaag ccaaaagact gcttttctaa gtttattgga gcagacatat ctttgaaatc
     8401 cactatagat aaatgcaaag ctactgtaat gtatccccct aatggcctcc cattaataat
     8461 aaaaggaaac agtggcgttg gaaaaagttt tttagcaagt ttgatctatc agtatgctct
     8521 tgatagaaaa gtaattcata atgacgcaaa atttgttgtt gtgaattgtg cagattatgc
     8581 aaataatcca gagctattgt cagcagtttt atttggatat aaaaaaggag cctttactgg
     8641 ggctgaaaaa gatactgcag ggatgctatc ttctgctaat ggaggatacc tttttttaga
     8701 tgaggttcac aatctaagtg cagaaaacca agagaaattg tttcttctta tggattctca
     8761 aaagtatcgt aaacttggtg aaagtgtgca atgggagtat gcaaatgttc gccttatctt
     8821 agccacaaca gaagataaaa atacctcttt gttagcaact tttagaagac gcatcccagc
     8881 tgaaatcact ctgccagatt acaataatag aagtacatct gaaaaaattc aattattatt
     8941 tgaatttctt aaagatgaag caattacaat tgattcaaaa atattttgtt cgattgaact
     9001 ttttactgat cttttatcga aaacatttga aggaaatgtt ggagaattga ggaatgaaat
     9061 caagcttctt tgtgcagaag gttatttagg aaataagaga aagtcttcaa tttatttagg
     9121 ggacaaacta gacagcggtt tttggataga tccagaaatt agtatagatt taaaaaaaat
     9181 gtttcttaaa tcactttctg aaattgattt gattgaactt tttcaaaatc acatttcaat
     9241 tgaagaaagc atgagtcaat taagagatag aatacttaaa gagtgtgcag gttcttctga
     9301 gtataattat ttagaaagtg acgaatttat agcattaaga aactatgttg ttaataaaat
     9361 atcaccaatt attgattcga caggtctatg tttattagat gaattcttgg cggatatcag
     9421 tctatttata atgtttattg atgtaattga agaaacatca agaaattttt tgctgtctaa
     9481 gttcagaaaa tttcgtatga aaaatgataa acaaaaatta ttggcaaatg agatttggag
     9541 tagtttagaa gtcgaagaaa gtaaacaaga acttttgttg aaatggatac tttttcttgt
     9601 aaagaagttc tatgtgaaaa taccagaaac ccattgtctg atagttatgc acggtaaaat
     9661 aacagcttct gcgatcgcaa gggaaacaaa taagttgctg aatacatatg tttatgaggc
     9721 tttcgatatg ccaattgaag gtgagactag tgacttaatt aacctaatca acaatttttg
     9781 taaaagtata gatacgacga atggactcat tctgctagtt gatatgggat cattggaaca
     9841 aatgtatgaa aaaattgaat ccaatgtaat aggtgatttg gtaattttaa acaatgtttc
     9901 tacagcttta gcgattgaat gtgggattca agtttgccaa aaaaagccaa ttagtcattt
     9961 ttaccagatg gattttgatt cgtttcaagt taaagttcag tattataaag gattatcaca
    10021 aaagaaaaat gtaatagtat cttgtctctc tggtgagggg atttctgaaa aagttaagga
    10081 tattttaaaa cggtatctcg ataatcaagt ggagattttg atttttgatt ttaacgcatt
    10141 aaagaaaata gcaaaggaaa aagatactat gatttttaag aatacaattt gtgttctttc
    10201 aaccactgaa ttttacattc aaggaatcga ttgtttaaat ttagaaaatc taattaatgg
    10261 gaatcaaacc ttagaaaaat taaataagta tatggactcg gatagctgtg agttctgctt
    10321 aaatgaatta gttaaactct ttactattga aggcgctagt actaagcttc gctttttaga
    10381 ttccaaaaaa gtattcaatg agatagaaaa agtactatat ttgtatgaaa aatattacga
    10441 tgtcaaaatc ccaagttttc tgagaattaa tctatttcta catctttctg gaatgattga
    10501 acgaattatg attggtgatg gaataacaaa tgaacatttg aaagagggag cgcaactatt
    10561 tgatactttt ttaaatgtat caaaagattt tttttcagaa atcaaagata tttactgtat
    10621 tgaaataccc aaaggagagt atgagttaat ctatacaatt tttgagcaga ctattttcta
    10681 aatagcatac tagcgtctaa aaaaatgaaa gggtgtccaa agtatattta gacgctcatt
    10741 taattaatat ttactgtatt ttcccgcttt attggataat gttagttggc acagtaattg
    10801 cttatataaa agtataagaa gaaaggagag aacaaaatgg cgttttggca aacattttta
    10861 gttgtgttgt atggattttt cattaactgg gataaggaag ggcccaaaat cggaacctcc
    10921 caacctgtcg ttgcaggttt cttgaccgga cttattatgg gagatattca aactggactt
    10981 tatatcggtg ggactttgca attaatgaca ctaggtatta ctagttttgg tggtgcatca
    11041 gtaccggatt atcaaacagc agcattgatc ggtacttatt tagcaatctc aactaaccag
    11101 gatgcttcta taggaataac tttagcaata ccggtagcaa tgttaattgt acaactagat
    11161 gttctaaagt ggtcaacaaa catttttttt caacaaaagg cagaaaaatt cgcacaaaaa
    11221 gaagattatc aaaaattaga gtggatgcaa tatttggcat caattaatac aagctttgta
    11281 tctggaattc ctgttttgtt aactgtgata ttaggcccaa cgttagtggg aagtgcaatc
    11341 aattatattc ctgaatgggt taccggtggt ttaaaggtag cagggggact attacctgct
    11401 gttgggatag gaatgctact taaatattta cctacaaaag attactttgc ctatttgtta
    11461 gttggtttcg ttttggcagt ttatttccaa ataccaattt tagggatttc gttacttggc
    11521 gctgcaatcg cactaatcgt atataaaaat agatcaaata atactcaagt agcaccagct
    11581 gcaacaggag gttttgacga agatgaataa gaaactgaca aaaatcgaca aacaagtaat
    11641 tttccggtgg attctcaatg gtgcaacttc attaaattat gaaaaaatgg aagggttggg
    11701 ttatgcgtat tctatgcttc cttttatcaa ggacacatat aaagatgatc ctgaaggaat
    11761 gaaacaatcc gttttagctc acctacaatt ttttaacact acgccgtata cagcgcctta
    11821 cattattggt atgaatgttg gaattgaaaa agaagaaaaa aataagtctt tggaagcagt
    11881 aagtgctctg aaaacaggtc taatgggtcc tttagcggga attggagata gtgtatttgt
    11941 agttattcca tggactattt ttggagcaat tgcagctaat atggcattgg aaggtagttt
    12001 tgttggaatt attttgtgga tactggcatc aattttatta aggattactg cttatccttt
    12061 ataccttgct gggaaagaat cgggtgcgag cctactaact caaattgaaa caaaattaaa
    12121 gtctattact gatgcagtat caattttagg gttaatggtg gtcggtgcac tcattgccac
    12181 agttgtaaaa gtgaatgttg gctttgaatt taaacaaggc gacttaacaa tgaccggaaa
    12241 tgaaatcttt gatcaagtta tgcctggttt attacctgca tgtgtagtag caattgtgta
    12301 ttatttgtta ggacgaaagg ttaaaccagt ttatgtaatt ctattaatct tagtagtttc
    12361 tattgcgtta agagcgttaa atattttgaa gtaggtgttg aatatggatg aaaaaatgaa
    12421 aggtattata catgttcgta ttgatgatcg aatgattcat ggacaagtag caacacaatg
    12481 gacaaatcaa ttgagtgcta acagaattat ggttattaat aatgaagtag ccaatgatga
    12541 cgtaaaaaaa gctgtagttc gcctcgctgc accacctaat gttagaactt caataattac
    12601 aagggaagta gcagttaaaa atattctttc tggtaaatat gaaggacaaa aagttcttat
    12661 tgttgcagtt tctccaatcg atgttaaatt tttgattgat aacggtttac caataacaag
    12721 tgtaaacgta ggaaatttat caagaaggaa tggaacagaa cgcatccgtc cgacgataaa
    12781 tattactgaa gaagagagag aggcttttaa agaactaatt agtgatggag ttgaagtgac
    12841 agtgatacaa actcctagag attcaaaaga atttttaaag gattttattt attaagaaca
    12901 gaggatgagt ggatggagtt tataattaca tctcatggaa atattgccat tggatttgta
    12961 gatacattaa aaatgttttt tggcgataat ttaaattgtc atgtggtaac acttggagat
    13021 gcaggcattg aagaattccg tgaaaacatt gaaaaaatag tttctcaagt aaaaaatcaa
    13081 gaagttatgg tatttgctga cttgattggt ggaacacctt tcaacgaatt tgctaaaaga
    13141 agtgaagtat ttcaaaatgg gtttcaactt cttggtggca tgaatttagg aattttgatt
    13201 gaggctgtca atttgagatt acaaggaaaa aaaagcgatg atatcatcga aaatctaaga
    13261 aatatgaata caattgcgtg tcttgcagat atgcaaagac atactaacga agaggatgag
    13321 tgataaatgc aaaaaatttt ttacaagcct aaagattttt ggtttgggga ttgcatgcct
    13381 ttttataaag atggaacttt ttatctattt catcaacgag atacgagaaa tcctaaacct
    13441 ttaactgatc cttttgggtg gtcactagtt acaaccactg attttgtgaa atttgaagaa
    13501 tacggggaag taattcatcg tggtggcaac gatgacattg atcaatacat ttacgctgga
    13561 agtattgtcc aaggaatcaa tgagtattta gctttgtata ctggacataa tcgcaaagct
    13621 aagttggatg gaaaaacttc agaagtgtta atgattgcaa gttctaaaga tttaattcat
    13681 tggaaaaagg atggcgaagc agcaaaactt gttcctcaag aaggatatga taagaatgat
    13741 tggcgcgatc cttttgcaat ttttgatcaa gatcatggaa aatacgtttt gatactagga
    13801 gctagaaaac cagcaagtaa gaaaaagccg acggggagat tggtctattt tgaatccgaa
    13861 gatttaaaag attggaattt caaaggagac tactgggcta ataatgaatt taacatgatt
    13921 gaaatgcctg atatatttga aattgatgga acgtggtatt tacttttttc agagtattgt
    13981 gaagataaaa agactaaata tcgagtcgga gcaggattat tttcagattg gaaatcacca
    14041 gtagacgaag ctttcgacgg aaaagcctat tatgcagcaa gaacagtcgg aactaatgaa
    14101 actggccgtt ttctaactgg ctgggtggca acaaaagaag gggagaacga tcaaaataac
    14161 tgggattggg gcggtgcact tgttccacat caaattattc aaaagacaga caaaactctt
    14221 ggtgttaaac tgcctgaaaa aataattgag aattttaaag aaatcactcc attttcaagt
    14281 tttaagttag agaaagaatt tggaaaaaaa gaaagagtaa ttgttcctaa aatcgaagat
    14341 tattttctat ttgaaacaac tttgactatt acatcgttaa caaaggagtt tgctttaaaa
    14401 ttatttgtag atagtgatac tcaagaagga tacgaatttc gtatttcatt gattaataat
    14461 cagcttactt tcggaaaaac tccgaactat ccttggcctc aaatgtttga taaggggctg
    14521 caacgaccac tatttttgga aataggcaaa gaatatgaac taaagttaat tgttgatgat
    14581 acgatagctg ttttatatat tgataatgtt gctttaagta ctagaatgta tgataaagtc
    14641 ggaacagcat taagtatgac tgttacggag ggagcaatca aggtagataa actagactat
    14701 tcaataaatt atgaatgtgg attttaaaac aattgaaggg atgatgtaag tgaaattaaa
    14761 tggtttacaa catattggaa ttccaacaaa agattttgga gcttcaaaaa tcttttatga
    14821 atccttaggg tttagtctga ttaatgaaga aatgaatgtg ggaagtaaag tcggcttttt
    14881 cgagttgaat ggaacgataa tagaaatatg ggaagataaa actactgagt gtagaggagc
    14941 cattgatcat ctagcattag atacggatga catagatgag gtattcaatt caattcaaga
    15001 tttaggatat gaattattag ataaaaatat tatggaatta ccgttctggg aaaatggaat
    15061 ccgttacttt aatttctacg gaccaaatca tgagattata gagataagcc aaatgaagaa
    15121 ataaatagat aacgaagtgc tctaagttgg tatgaacgaa aagtacttca ttttttggta
    15181 tcagcatttc aatagtttaa tgagaattta ctatttcaaa ttaattcaaa gtgacagtat
    15241 tttttactta tttggtttca aattttgtaa tccttcctat ttattggaat acactccaca
    15301 ttttgtatac aagtcatatc atgttttagc aaagctctta ccaagcaaag ttataatgat
    15361 gttttccaaa gtttgatctt tcgatggagg ctaacacata ttttttgcag gacagccaaa
    15421 attagatgta tagaatagag tctgtgaggc gtatagacag tttattgtct gtatgccttt
    15481 ttttattttg aaaaattttt agtatttttc gaaaaatgct cactcctaga gtaagcgccc
    15541 catagaacag taccttacta acaaatgcac ctcaagatat acttgagcta tcaagaagtc
    15601 tggaggtttt ct
//
LOCUS       DAPBAF010000057        15468 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.057, whole genome shotgun sequence.
ACCESSION   DAPBAF010000057 DAPBAF010000000
VERSION     DAPBAF010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15468)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15468)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15468
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.057"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(122..472)
                     /locus_tag="RD451_002363"
     CDS             complement(122..472)
                     /locus_tag="RD451_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567579.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRTSQNLAKEQMTTE
                     EIAEVLNAAVIKNRSVSIQKEERNAEGYYPEDIVGKILGSDELGIYVGKDKIHYDEIR
                     HIEFYQDNKWSRLE"
     gene            complement(465..1790)
                     /locus_tag="RD451_002364"
     CDS             complement(465..1790)
                     /locus_tag="RD451_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HDT7567580.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRS
                     DNTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTKSLNLFTTEETRSQRRKKLAQMIQERIKEELGLIA
                     TVGVGDNPLLAKLALDNEAKHNEGFIAEWTYENVPEKVWNIPEMTDFWGIGSRMKKRL
                     NQMGILSIRDLANWNPYTIKNRLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLNIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQINEEN
                     LDKIIDKIRQKYGFTSIVHASSMLESARSITRSTLVGGHAGGNGGIKND"
     gene            complement(2161..2745)
                     /locus_tag="RD451_002365"
     CDS             complement(2161..2745)
                     /locus_tag="RD451_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDT7567581.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSST
                     GQLMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLKTLVDSG
                     TPIKTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
     gene            complement(2957..3160)
                     /locus_tag="RD451_002366"
     CDS             complement(2957..3160)
                     /locus_tag="RD451_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567582.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
     gene            complement(3170..3592)
                     /locus_tag="RD451_002367"
     CDS             complement(3170..3592)
                     /locus_tag="RD451_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567583.1"
                     /translation="MKNKFILSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELT
                     PLDRDGIAIGNPTNDLTVTENYLIVSPLLALAASKTIRVTGTMIFDKVGWPSRPPQSR
                     NWKEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
     gene            3830..4444
                     /locus_tag="RD451_002368"
     CDS             3830..4444
                     /locus_tag="RD451_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDT7567584.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDYVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVKLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSADAKDPQ
                     RRLVYKSIVEDLKNGVAIAKIAKDYNVTRQTVYRIKKDSMVNDK"
     gene            complement(4609..5433)
                     /locus_tag="RD451_002369"
     CDS             complement(4609..5433)
                     /locus_tag="RD451_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567585.1"
                     /translation="MIERLKDFMISVWDVAMLADESNYTSSIYRLEDSNWIEISLELK
                     TLPNSVNYIIRDITSEAQQLVNYMHGHESIPFSLILLKRSKNISNTRDRFISIITACE
                     IGVKEFYQQEKPDLTLIFENLQSPPVDKLLGSMFKGYFNIEFPKEIRKEIKNFIEKRN
                     KLVHSPQGSKPTIEECFECYMAVLKTFNFFYKINDSFMYRDFYEESIELTPTEPNKSQ
                     ITLSKELERKVESQELAIGISITNVSTYKELYEAKSQDNKDFVENIDKEPTNTVGD"
     gene            complement(5457..5612)
                     /locus_tag="RD451_002370"
     CDS             complement(5457..5612)
                     /locus_tag="RD451_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567586.1"
                     /translation="MEYKFNLNLKEVLPTQGTININGQDNDDDIVIKKIEFIDSDINV
                     FFILKKN"
     gene            complement(6071..6328)
                     /locus_tag="RD451_002371"
     CDS             complement(6071..6328)
                     /locus_tag="RD451_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HDT7567587.1"
                     /translation="MIKAWSDDAWDDYLYWHEQGNKSNIKKINKLIKDIDRSPFAGLG
                     KPEPLKHDLSGKWSRRITDEHRLIYRVENETIFIYSAKDHY"
     gene            complement(6321..6590)
                     /locus_tag="RD451_002372"
     CDS             complement(6321..6590)
                     /locus_tag="RD451_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HDT7567588.1"
                     /translation="MEAVAYSNFRQNLRSYMKQVNEDAETLIVTSKDVEDTVVVLSKR
                     DYDSMQETLRTLSNNYVMEKIRRGDEQFSKGAFKTHDLIEVESDD"
     gene            complement(6721..6900)
                     /locus_tag="RD451_002373"
     CDS             complement(6721..6900)
                     /locus_tag="RD451_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567589.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESRIMCIALDLL
                     IAQEKAGFEVPALKK"
     gene            complement(7281..7988)
                     /locus_tag="RD451_002374"
     CDS             complement(7281..7988)
                     /locus_tag="RD451_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567590.1"
                     /translation="MNKVVYQLTTEDVSQFLTNKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYMESETSQTKVTVSHNRLDVYKRRPDTLKKGAELLRLETEKYIMNVYLERS
                     ELVENFVSYTICRKHYYSESEYYSIFESMELMEEEMEELNSKDATVDDYYLVFTRFLT
                     CGTESIVLMGMDYELTVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNE
                     LDRKRMPYQRFERKKGQ"
     gene            complement(7981..8418)
                     /locus_tag="RD451_002375"
     CDS             complement(7981..8418)
                     /locus_tag="RD451_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567591.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYHETRVPKKHYKEKLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNGKWFFQALLCLEVGVKPSTIKPSEYQALE
                     LTYAKFAQIKKAKAMASDWLDTFENIEKNGAFYTIESEEKDNE"
     gene            complement(8433..8684)
                     /locus_tag="RD451_002376"
     CDS             complement(8433..8684)
                     /locus_tag="RD451_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567592.1"
                     /translation="MKTQHKLLTVKEVVQILVDKEVISEKVAEALLIPRYWTIETPLV
                     EDAPTMLFEDLVKIAGYELHYQENMETYEIEYWLTKLEN"
     gene            complement(8684..8890)
                     /locus_tag="RD451_002377"
     CDS             complement(8684..8890)
                     /locus_tag="RD451_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HDT7567593.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGERAKCIKSYRLYQC
                     PTCGKKYTLSYGDYVLIDEKVKKR"
     gene            complement(9327..9587)
                     /locus_tag="RD451_002378"
     CDS             complement(9327..9587)
                     /locus_tag="RD451_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567594.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIESMQIRNPDHFTRSMGI"
     gene            9662..9865
                     /locus_tag="RD451_002379"
     CDS             9662..9865
                     /locus_tag="RD451_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HDT7567595.1"
                     /translation="MIKTVKFVTVAIRLKVRWCVCAYFQNLTERRSLLPVETALGLMI
                     SFGSLIATIIFGILAVVNNNQKK"
     gene            complement(10006..10491)
                     /gene="ssb"
                     /locus_tag="RD451_002380"
     CDS             complement(10006..10491)
                     /gene="ssb"
                     /locus_tag="RD451_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDT7567596.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQNGNR
                     EADFINCVIWRKPAETMATLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRAHADQSSSSPSPTTFEQRDVATPNNNGLNASQNPFGGQSIDISDDDLP
                     F"
     gene            complement(10494..11393)
                     /locus_tag="RD451_002381"
     CDS             complement(10494..11393)
                     /locus_tag="RD451_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HDT7567597.1"
                     /translation="MTPTQFAAKTRNLAKSTGLNAQLVQRHFMMDRLIEQISESKYKN
                     DFILKGGFLLGSKYGIDRRTTIDIDTTFRNSKLTEEKLKSIFNDLTRKPTKEGIVFSI
                     QGMKETREADFYPGFQIKLVANLEKVRVPFKMDVTTGDSIYPEVDTHYHQLMFEDKKV
                     EIPAYPTEQIIAEKLSATFSFGTDNSRAKDYYDLFTIPKLENIDTKELYKSVRNTFTK
                     RGDTKPLSFYYEREMDKIRGNDYLEKQWEKYRSVNTFANSISFTDTVNEIDHLMKSVI
                     KIENQERKRQFKRSQQMNQEMER"
     gene            complement(11406..11999)
                     /locus_tag="RD451_002382"
     CDS             complement(11406..11999)
                     /locus_tag="RD451_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HDT7567598.1"
                     /translation="MQDKLKELLAIRDGNLSMKEARKFGIAATTVQRLVNQGKLIKVD
                     RGYYVEDGHGIDDLFWLQQRFSRGIFSHETTLDIYQLSTNMPKFIHLTFPHGYNVDRS
                     ITKEQQLQFHFVKKEVYELGKVEGTSFQGNPITMYDKERTLCDIWNPRYEFEYEMKLE
                     ALKEYMEDPLRDPSKLRDYMTKLHVEKEMKYHMQSLY"
     gene            complement(12075..12224)
                     /locus_tag="RD451_002383"
     CDS             complement(12075..12224)
                     /locus_tag="RD451_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567599.1"
                     /translation="MRNTTHKQQEIENQKAKIRLEQEKLRANKRRLQQLKNQQRIQKE
                     IELDR"
     gene            complement(12240..14444)
                     /locus_tag="RD451_002384"
     CDS             complement(12240..14444)
                     /locus_tag="RD451_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HDT7567600.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFSGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFKVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQAGADHGKIFKRLWINSLEKEAIYQGFQQLRDAEETYP
                     KFEEAQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FQKEPYFEGKAQVIAQNGAFDAKLDPNETQATQEAFEDYLKEKGVQLGKQPGTIHQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLKAEAIPTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTAAAFEQ
                     LSPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKTVGKVPVDLGWKKLFGK
                     ESDRKEKEEEPLLPKVTKGEAVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGILLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGEQKGTQATFLANIQKFVSHLLEVVPGQIQSTDFGSTLQEVKA
                     ASEKQEATRHLGVCPKCREQEVLLYQNVAACTSEACDFKLWTTIAKKKLTATQLKEII
                     QNGRTSQSVRGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNYKKRTRRTTK"
     gene            complement(14455..>15468)
                     /locus_tag="RD451_002385"
     CDS             complement(14455..>15468)
                     /locus_tag="RD451_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HDT7567601.1"
                     /translation="ELKPKHERQNFLVRDDRLDHAVAFLWKDPQTNETVGASYQGTFI
                     DYERFGERGTYKHIDKNSTANHGFNLKIGDPKQLKFFESSIDLLSYAALNRDQLNDTW
                     LVSMEGLKHHVISHYFGEAVSELRKKQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDP
                     FTNQKVRCERGIANDWQVPKEYKVIYEEVAKEEKITPEAIMAIHKTENNLQLTNQLVS
                     AHKVNASFGQQLSVNDSIEAINLKDICREVAKELKACERVDGTYDFDRFYQEKGDINA
                     QILFSYKAEQYYKGYKNHEHEFVPEVKKDWNDQLKHEIYQQEIRKQKRAMLFQQGRQQ
                     ERE"
BASE COUNT         4349 a         3044 c         2442 g         5633 t
ORIGIN      
        1 aaggcactct cttcgggttt tcggtctgta ctgaaatcaa ggtattattg ggaatcctag
       61 cttaaatcat agataccgta agggatttta ttctttattt aaaactttgc aacagaaccg
      121 ttcattctaa tcgactccat ttattatcct ggtaaaattc gatatgacgt atttcgtcgt
      181 agtgaatttt gtcttttcca acgtagatcc ccagctcatc actacctaag atcttgccaa
      241 caatatcttc tggatagtat ccttcagcgt ttcgttcttc tttttgaata gatactgatc
      301 tattttttat gactgcagcg ttcaatactt ccgcaatctc ttcagtcgtc atttgttctt
      361 ttgctaaatt ttgactggtt cgttgttcat tgtcggcatc aatttcttca gtatgatcag
      421 ataaataaaa ccctgcccac tttaaacgtc cacgatcatt gtaatcaatc atttttaatt
      481 cccccatttc cgcccgcatg accaccaaca agtgtgcttc tagtaatgct tctagcgctt
      541 tctaacattg aagaagcatg tacaatcgac gtaaaaccat atttttgccg aatcttgtca
      601 ataattttat ctaaattttc ttcgttaatt tgcttttgtg gatcactaaa taaatccagc
      661 tgaagcgaat cggtgtacac aagcttgcta taggttattc caacgtgcct tacttcttgt
      721 ccttcataat acttatcaaa caagaaaaga caataattct gcaattcctt tgtattatct
      781 gtgataggta ttttcatctg gtgtgaaaat cctggtctcg tttctaagat cgacgtacca
      841 atgtttaaat gaacacatcc tgttttacaa ttatgctgcc tgatacgaat ggctacttgt
      901 tccgccattt cttttaccac cagctcgatt tcatttcttc tagtataatc tcgtggtaac
      961 acttgtgaat taccataaga tttttccttt gtcggttctg gcgggattgc tatatctgtt
     1021 cgatcgattc cgttagcatg gaagtacagc tgtaatccaa tcacacctaa tctattctta
     1081 atcgtataag gattccagtt agcaaggtct ctaatgctca aaattcccat ttggttgagc
     1141 ctttttttca ttcgagaacc aattccccaa aagtccgtca tttcgggaat attccatact
     1201 ttctcaggaa cgttttcgta cgtccattcc gcaataaatc cttcattatg ctttgcttca
     1261 ttgtctaagg ctaatttagc caaaagggga ttatcgccga cgcctaccgt agcaatcaaa
     1321 cctaactctt ctttaatacg ttcttggatc atttgagcga gcttcttcct tcgctgactt
     1381 cgtgtttctt cagtcgtaaa aagattcagt gattttgtca cttttaaaat cgattcatcg
     1441 atcgagtaaa tcagtagatc ttcatcagcc acatatcttc tgaaaatatt atttacctgc
     1501 atatttcgct tgatatatag gttcatacgt ggtggaacaa cgtgtagtgt tttaggaaat
     1561 ggttgtggta agtcacgtgg tctactcaca tttgtaatac cataccgctt ttttgcttca
     1621 ggagaagaag ctaatatcaa tcctgaacca gtattatcag atcgactcat aacaacaagt
     1681 tctgttgtta atggatctaa atttctttct atacattcga cacttgcgta aaagcttttc
     1741 atatcgatta aaaagtaatc atttactggc tcttttgaat aatccatcat aaataacact
     1801 ccattcttcc acattataca aacatatgtt cgatgttgta aagaagaaat agctaaatac
     1861 ataaaaaaag aagcataggt atgctatcac cctgcttctt cttatgattt gtatgatcaa
     1921 tttattctat cactttacta attaatttga aaatctaata aaaactctca ctctaaaaga
     1981 gtgagagact gcaaattaga gtacggactt ttttggagtt ccgttcttta atattaacaa
     2041 atgaataaaa tccttacaac atttgataat aagttatcag tagacactta caaaaaattc
     2101 tcatactatt gtcacttttc tagataaatg gcaaaaattt tcagcattaa atgacaaaaa
     2161 ctaatgagaa tttgtctttc catttttctc ctccattttt gccaaataac gataaatggt
     2221 ggttcttgag acgttccacc gttccgcaat agtcttaata ggtgtaccgc tatccactaa
     2281 agtcttcagt aattccaaat cttgttcaga caatttttca ggacgaccac caaaccgtcc
     2341 tcttgcacga gcagctgctc gtcctgctgc ggatcgttcc aggatcaaat tacgctcaaa
     2401 ttctgcaaat gccgcaaaca aatgaaacat gagctgtcct gtagaacttg atttgtccat
     2461 cgtaatattt tcttgaatac tatgaaaact cacaccacgc tcattcagtc gattgacgat
     2521 tgaaatcaaa tcttccatat ttctacctaa acgatctaag cgccaaacga caagtgtatc
     2581 gccagagcga acaaaatcaa tggccatttc taatcctggt cgattacttt ttgccccact
     2641 catatgatca gtaaaaattt tttcacaacc aaatttattt aggctgtctt cttgtaaatc
     2701 caaattttgt aaaccagtag atacccgggc gtatcctatt ttcaaaaaaa tcactccttc
     2761 attaatttta ttgtaacata actttatcca tatagtttaa ctgaacatag atattgttat
     2821 gggtttatga acatgaaatg aattgttttt ttgaaaaata aagcaaaaaa aggaagtgtc
     2881 cagaaatggg tgattttatg aacactttca attagaaaaa aagaatgtcg actagacact
     2941 ctttttttta aaatcattat ttttcttttt gatatgtttt ttggtctctt ttttttcttt
     3001 tttcttcaga atcttctaga ttagaaattg atttttgaat tttttgtgtc tcctgtaaag
     3061 ttcgctgaac ttgtaaagct gattcttctt tcggtaaatt aattttactt agaatatcgc
     3121 tatcttgata aaaatttggt gtgttcacaa attctggcat aaaaaatccc tactttctag
     3181 ttaaggttcc tgaataagtc gcaatccaat tgtttccagc tgatttataa ctttgtaaat
     3241 acaattttcc atagtaccaa taaccatttc ttttttcttt ccaattccgt gattgaggag
     3301 gtctagaagg ccaaccaact ttatcaaaaa tcatcgttcc tgtcactcgt atcgttttag
     3361 aagctgctag agcaagtaat ggagaaacta ttaaataatt ttcagtaaca gttaagtcgt
     3421 tagttgggtt accaatggct attccgtccc tatctaaagg agttaattct tggttattat
     3481 ctactacagt agttggttca tttgtactat cagcaaatgt aggaattgta gttccagtta
     3541 cactaattcc aatagttaaa atacctaaag ataaaataaa cttatttttc attgtctatc
     3601 acctcgaaat caaaactaag aaaacgtttt cttaataaat cttaacagat aaatcaagtt
     3661 atatactaga aaattcataa aatatatttt taatgtcata atcgtttaaa ttttcttgat
     3721 tgacatttat ttacaaaaaa tattgccatt taaaaagaaa agtgacatat ggcttcctcg
     3781 tgtatgatta gggtgtattt taaatagttg cagaaagtag gtaaaagttt tgagagttgc
     3841 atacatacgt gtctcatcga tcgatcaaaa tgaacaacgc cagattgaag aaatgaaaaa
     3901 attcggtgca gagagaattt tcatcgagaa acaatctggc gcaacgatta ctcatcgacc
     3961 tgttttccaa gaagcattag attacgtccg agatcaagat atttttattg tggaagctat
     4021 tgatcgactt ggaagaaatt atgacgagat catcgcttca gtcaattact tgaagaagaa
     4081 aaatgtgaag ctgatcatta ctagtttacc gatcatggct gaagcaattg gcaatcctct
     4141 cctggataaa ttcattaagg atctgatcat ccaaattttg gccatgatcg ctgaacaaga
     4201 acggactgaa tcgaaacgtc gccaggcaca aggaattaag atcgcaaaag caaacggcgt
     4261 ctacaaaggg cggcccaaat tatacagtgc agacgcaaaa gatccccaac gtcgccttgt
     4321 ttacaaaagc atcgttgaag atcttaaaaa tggtgttgcg attgctaaga ttgctaaaga
     4381 ctacaatgtt acgagacaaa ccgtgtatag aataaaaaaa gacagcatgg tcaatgacaa
     4441 atagttgatc atgctgcttt tattatcttc tcatctttaa tttcctacat ataattacta
     4501 tctataaaat taagtcttac tcagaacaga taaagcataa aattccaaca aaccattttt
     4561 tacttaacta aataaagagt ctgttaatat aatcttcact tatttacgtt aatcccctac
     4621 tgtatttgtt ggttccttat ctatattttc tacaaaatcc ttattatctt gtgatttagc
     4681 ttcgtataat tctttgtatg tcgacacatt ggttatacta attcctatag ctagttcttg
     4741 agactctact tttctctcta gctcctttga caaagtgatt tgagatttat ttggttccgt
     4801 tggagtcaat tctatagatt cttcataaaa atctctatac ataaagctat cattaatttt
     4861 ataaaaaaaa ttaaatgttt ttagcactgc catataacat tcaaaacatt cttctatagt
     4921 tggtttactt ccttgaggag aatgaaccaa tttattacgt ttttctatga aatttttaat
     4981 ttcctttctt atttctttcg gaaactcaat attaaagtac cctttaaaca tgctccctaa
     5041 taatttgtct acagggggag attgtaaatt ctcaaatatt agagttaaat caggtttctc
     5101 ttgttgataa aattccttta cccctatttc acaggctgta attatcgaaa taaacctatc
     5161 tctagtattt gatatatttt tacttctttt aaggagtata agagaaaagg ggatactttc
     5221 gtgtccatgc atgtaattaa ctaattgttg agcttcagaa gttatatctc taattatata
     5281 gttaacggaa ttaggaagtg tctttaactc taatgaaatt tctatccaat tactatcttc
     5341 taatctgtat atgctcgaag tataatttga ttcgtcagca agcatcgcta catcccaaac
     5401 actgatcata aaatctttta aacgttcaat catttcagca atattgctaa aatcagctaa
     5461 tttttcttta gaataaaaaa aacatttata tcagaatcaa taaattctat tttttttatt
     5521 actatatcgt catcattatc ttgaccattt atgtttattg ttccctgagt ggggagtact
     5581 tctttcaaat tcaagttaaa tttatattcc attacttctc ctccaatata taaaaattac
     5641 ttaactgtat ccaaatttaa tatgtaaata aatcattaat ttttagctaa attctatgag
     5701 aagtttattt ttgttgtttt tgctaattaa ctaaaactag tacaaaaaat ttaaaataga
     5761 ttattaaacc tattgcttat tctattcagt catatatata agcgtcatcc tttagtaact
     5821 aacatcccac actacaatag tattataaca tatctattca acttcaaatt gttgaaattt
     5881 aagccattta tatttacttt tcctcaactt tagaaatgat tttactaacc ttatatccgt
     5941 aatacgcgta acaaacacat tcattaataa caatcaacac taagctatat tagcttttta
     6001 aatgactagg gtaaataaaa taaggatcaa aaacttttaa gtttctgacc ctttccttac
     6061 ttccgattgg ttaatagtga tcttttgcag aataaataaa tatcgtttca ttttcaactc
     6121 tatatatcag tctatgttca tctgtaattc ttctggacca ttttccagat aaatcatgct
     6181 ttaatggctc aggttttcct aatccagcaa agggggaacg atcgatatct tttattaact
     6241 tgttaatctt ttttatattg cttttgtttc cttgctcatg ccaataaaga taatcatccc
     6301 aagcatcatc agaccaagcc ttaatcatca gattcaacct cgattaagtc atgtgtttta
     6361 aatgcacctt tggagaattg ttcatctcct cgacgaattt tttccatgac gtaattatta
     6421 gaaagtgttc tcaacgtttc ttgcatagaa tcataatctc tttttgataa tacaacaact
     6481 gtatcttcta catctttact tgttacaata agtgtttcag catcctcatt aacttgtttc
     6541 atataactac gtaaattttg gcggaaattt gaataagcta ctgcttccat tcctttcacc
     6601 ccttatttat ttctataaaa caattgtaca ttatattgta caattaagca aatgattaat
     6661 attctaactt cttataatta aaagtgctat cacttttagt ttttaggata aaaagtgacg
     6721 tcactttttg agtgctggta cctcaaatcc tgctttttct tgggcaatca ataaatctaa
     6781 cgcaatacac ataatcctgg attcactttt gccgtacttc tgctttagtt gctgcaattc
     6841 tttttgtctc ttttcatcca acgtcacggg taaccgttta tttcctattg caattggcat
     6901 tagtactctc tcctttcatc gaaataaccc tattaaaaat atggctgcaa tcaacttgaa
     6961 tattagactc acaagggtta acacaaagcg ccaaaagatc aaacaaaata ccagtattcc
     7021 taagaatact acgaagttta aatgtagagc tgcaccatga cgcataagta tctcgccaac
     7081 aaacagtacg aacaatagag gaatgatttt attcatatgg atctccttct ttctcttagg
     7141 ttatcgggct ttgcccgctt atttcgcacc acctaagcgg cgggggcggt tggatcgatt
     7201 ggtgcgaaat aagaaccatt cccttaattt caaggttttt tgttcttatt tcacacatcc
     7261 tcacttttcg gtataaatgg ttattgacct tttttccttt caaatcgttg atatggcatt
     7321 cgtttacggt caagttcatt ttggatttct tctgtatcgt cgtaagtgta ggtgtctaaa
     7381 aaatcagtta aagtcgtgta ccagtcgtcg cctgggttat ctacttcttc tacatattcc
     7441 ctcaaaaatg cttcgggtac agtgagttca taatccattc ccattaacac gatagattcc
     7501 gtcccacacg tcaaaaatct agtaaataca aggtaataat cgtctaccgt cgcatctttg
     7561 ctgtttagct cttccatttc ttcttccatt aattccatgc tctcaaaaat tgaataatat
     7621 tctgattctg agtaatagtg tttcctgcaa atcgtgtagc tgacaaagtt ttcgaccagc
     7681 tcactccttt ctaggtaaac attcatgata tatttttctg tttctagtcg tagaagctcc
     7741 gctccttttt ttaatgtgtc aggacgacgt ttatacacgt ctaaacgatt atggctgact
     7801 gtaaccttcg tttgactcgt ttcactttcc atatacaact gttcttccac tctttgaata
     7861 aagtacttca tttcttccat acaactaaag tctttttgaa tccgtctgat tacttcattc
     7921 aagtgttctt tgtttgttaa aaattgcgaa acatcttctg ttgttagctg ataaaccacc
     7981 ttattcatta tctttctcct ccgattcaat cgtataaaat gcaccatttt tttcgatatt
     8041 ttcaaaagta tctagccagt cgctagccat tgctttagct ttcttaatct gtgcgaattt
     8101 tgcataagtc agttctaagg cttgatattc ggaaggtttg atagtgcttg gtttgacacc
     8161 tacttccaag catagtaagg cttggaaaaa ccattttcca ttttgttttt tcagttcttc
     8221 cagtgttcga tagtacgtcg caatgagatt catttcgaca cctgattcaa tcatttcttc
     8281 cactgcgact gacaattttt ccttgtaatg ttttttgggt acacgtgttt catggtatag
     8341 gaacgtcata tcctccattt tttgtgccat tttatccaaa ggtaatttga caaattcgtc
     8401 atagtaattt tgagccatat tttttctcct ttttagttct ctaatttggt taaccaatat
     8461 tcgatttcat aagtttccat gttttcttga taatgcagtt catatcctgc aatcttcact
     8521 aggtcttcaa atagcatagt cggtgcatcc tctactaaag gggtttctat cgtccagtac
     8581 cgcggaataa gtaaagcttc tgctactttt tcagaaatga cttctttgtc caccaaaatt
     8641 tgaacgactt cttttacagt caataatttg tgttgtgttt tcatcaccgt ttctttactt
     8701 tctcatcaat caaaacataa tcgccataag acaaggtata ttttttcccg catgttggac
     8761 attgatacaa acgatagctt ttgatacatt tcgctctttc tccacaatcg cattcgacag
     8821 tatgtggtgc atgatagttt gggaataatt cgctgaaggg aacaccccaa taatcaaatt
     8881 tctttcgcat gattgattct gcctcctctt aggaaaggtt ttatttcctt tcgttagttc
     8941 tttctttatt gatttgttgg ccagaatgaa tcaacgaaaa gcgacaagga caagggcgcg
     9001 cagcgtgcca tttacccttg tccttgtcgc tttttggtga taaaaggcaa cttgttgccg
     9061 gtctggcaaa tcaataaaga gatagcgaac aggaacgaac cttttggtga gaggaagttt
     9121 tttctatttt gtcttgcttt gcaagacacc atatcttagt gaacgtgcaa cgttcacttc
     9181 ctttcttctc gaacggcggt ggcggttgga gtgagagaaa ggtttttcaa ttgagaaggc
     9241 acttgtgtct tcctaaaaag gtcttttcct gtttctatgt aaaacaaaaa gagctgcaat
     9301 cctcatttag gactgcagct cttcttttat atgcccatcg atcgcgtaaa atgatcgggg
     9361 tttctaattt gcatcgattc aatgactaat tgattccgtt tattgaaatg acctgtgacg
     9421 gcaatattgt attttccatc atccataatt aacaatttat cgataatttc aatatctgca
     9481 actacacaat taatcgattc atgaattgtt tgtaaagtaa agcgaaccaa taatggttgt
     9541 gtttttatta ctcggatttt atcaagcaaa ccaacatatt tgttcatcac gatcacctcg
     9601 ctaaaattat agcaaaaaca gctaaaattg agaattttta ttcgatttta gatatgctat
     9661 aatgatcaag acagtaaagt ttgtgacggt ggctatccga ttgaaagtga ggtggtgcgt
     9721 atgtgcgtac ttccaaaatc ttacagaaag gagaagcctt ttgcctgttg aaacggcgct
     9781 aggattaatg attagtttcg gttctttgat cgcaacaatc atttttggaa tcttagcagt
     9841 tgtaaacaac aatcaaaaaa aataaccgtc agctttagcc ggtcgacgat tatttttcaa
     9901 aaataatatt aagctggtca ccgtcttaaa cggtgctgtt aggggagttg ttagcgcaac
     9961 tcctcttttc gtatccatta taacaacttt attgatcttt tacaatcaga atggtaaatc
    10021 atcatcacta atatcgattg attgtccgcc aaatggattt tgtgaagcgt tcaatccatt
    10081 gttgttaggc gtagctacat cccgttgttc aaaggtggta gggcttggac tgctggacga
    10141 ttgatcagcg tgcgcacggc tttctgtcgc tgctttactt tctaatagtt ggaaattatc
    10201 ggccacaact tctgtcacat acacacgttg tccttgttgg ttatcgtagg ttcgggtttg
    10261 aatccgtcca acaacgccga tcaaactgcc ctttttagct aatgtcgcca tcgtttctgc
    10321 tggtttgcgc caaatcacac agttaataaa atcagcttct cgattgccgt tttgattcgt
    10381 gaaatttcgg ttgacagcta gggtaaaagt cgctactgca gtaccactcg cggtataacg
    10441 taaatctgga tctttggtta agcgtcctac taaagttaca ttattgatca tctttatctc
    10501 tccatttctt gattcatttg ttgtgatctt ttaaactgcc gttttctttc ttgattttca
    10561 attttgatca cacttttcat taggtgatca atttcgttga ctgtatctgt aaatgaaatg
    10621 gaattcgcaa acgtgttaac tgagcgatat ttttcccact gcttttccaa atagtcattt
    10681 cctctgatct tatccatttc tctttcataa taaaaggaca acggttttgt atccccacgt
    10741 tttgtaaatg tatttcgaac acttttgtat aactctttcg tatcgatatt ttctagtttc
    10801 ggaatggtaa ataagtcgta gtaatctttt gctctcgaat tatctgtgcc aaagctgaac
    10861 gtagcactta gcttttctgc aataatttgt tctgttggat aagctggaat ctccactttt
    10921 ttatcttcaa acattaattg gtgatagtgt gtatctactt caggataaat agaatctcct
    10981 gttgtcacgt ccattttaaa cggtacacgt actttctcta aattagccac caatttaatt
    11041 tgaaatccag gataaaaatc ggcttctctt gtttccttca ttccttgaat agagaaaaca
    11101 atgccttctt ttgtgggttt tctagttaaa tcattaaaaa tgctcttcaa tttttcttca
    11161 gttaatttgc tatttctaaa tgtcgtatcg atatcaattg ttgtccttct atcgattcca
    11221 tattttgatc ctaataaaaa gccgcctttc aaaatgaagt catttttgta ctttgattca
    11281 gaaatttgtt caattagacg atccatcata aaatgccgtt gcactaactg tgcatttaat
    11341 cctgtactct ttgctaaatt tcttgttttt gctgcaaatt gtgtcggtgt catctttttc
    11401 ctccatcaat ataagctttg catgtggtat ttcatttctt tttctacatg tagttttgtc
    11461 atgtaatctc ttaatttact tggatctctc aatgggtctt ccatgtactc ttttaatgct
    11521 tctaatttca tttcatattc aaattcatat ctcggattcc aaatatcaca aagtgtacgc
    11581 tctttatcat acatagtaat aggatttcct tgaaaggaag ttccctctac ttttcctagt
    11641 tcataaactt ctttcttcac gaaatgaaat tgtaactgct gctcttttgt aattgaacga
    11701 tcaacgttat agccatgggg aaaagttaag tgaatgaatt tcggcatatt cgtagaaagc
    11761 tggtaaatat ctaaagtcgt ttcatgagag aagattcccc tggaaaatcg ttgctgaagc
    11821 caaaataaat catctattcc atgaccatcc tctacataat aaccacgatc aactttgatc
    11881 aattttcctt gattcaccaa tctttgtaca gtggttgctg cgattccaaa tttcctggct
    11941 tccttcatag ataaatttcc atcgcgaata gccaacaatt ctttcagttt atcttgcatt
    12001 tacttcccct cccttcgtta caaatacact acatcaaata tatcatagta gtttatttgt
    12061 aacaagatta acgtctatcg atctaattcg atttcttttt gaatgcgctg ctggttcttt
    12121 aattgttgca gtcttctttt atttgcacgt aatttctctt gttctaaacg aatttttgct
    12181 ttttgatttt cgatttcttg ttgtttgtgt gttgtatttc gcataggata accccttcat
    12241 tattttgtag tgcggcgtgt tcttttctta tagttcgttt ttttcttttc agaaaattca
    12301 aagcctgttg taaagtcttc ttttaaaacg atcgttgctt caaacgaacc tttctgacct
    12361 tttagtcctc tgactgattg gcttgttcgg ccgttttgaa tgatctcttt cagttgtgtg
    12421 gctgtgagtt tctttttggc aatcgttgtc cataatttaa aatcacaggc ttcagacgta
    12481 catgccgcca cattttgata aagcaagact tcttgttccc gacattttgg acaaacacct
    12541 aaatgacgcg ttgcttcctg tttttcactg gctgctttca cctcttgtaa cgttgatcca
    12601 aaatctgttg actggatttg tcccggtacg acttccaaca agtgagagac aaatttttgg
    12661 atattagcta agaaagtagc ttgtgttcct ttctgctcac caatctttaa taagtaactt
    12721 tcccatttgg cggtcatttc ggcacttgtt agcagcggct ctttttccac ggcttggcaa
    12781 agtaaaatcc ctttatttgt caccacaagc ttattttttt ctaccttgat atattccttt
    12841 tgtttcaaag tttcaataat atttgctcgt gttgcttctg taccgattcc ttctacttct
    12901 ttcaatatgg attgtgcttc ttcgctatcc acggtttttc cagctgtttt catcgctgtg
    12961 atcaacgtac cttcggtata aggttgtggt ggcttcgttt ctttttcaag gacttgtaga
    13021 tctaccgtca ccgcttctcc ttttgtcact ttaggaagta gcggttcttc ttccttttct
    13081 tttctgtcgc tctctttgcc aaacagcttt ttccaaccta gatctactgg tacttttccg
    13141 actgtcttta gctgaagctg ctgaacttgc gtcaagatcg ttgtttcttc ataggtatac
    13201 ttttccgcaa acatggccac cgttgttttt aacacttgtt cataaatagc ctgctgcagt
    13261 ggacttaatt gttcaaaagc cgctgccgtc atgaccgtct ttgtaggaat gatcgcgtaa
    13321 tgttcctgga ctttcttatt attcacatat cgactattcg gtgtatgaat aggagtagga
    13381 atggcttcgg cctttaaaaa gtgtttgtat tcgtctaagt gatccaacag atacgcatac
    13441 tccccttctg taatataagg ggtatctgtt cgtgggtagc ttagatattt cccttcatac
    13501 aacccttgca tggcttccaa agtatctttg gcactagctt tcatgagctg attcatttta
    13561 gattgaaggc tggatagaga aaaaagacgt ggacttgccg cacttttttt ctcggtttca
    13621 acttggtgga tcgtacctgg ctgttttccc aattgaaccc ccttttcttt taaataatct
    13681 tcaaatgctt cttgcgtcgc ttgggtttca ttcggatcaa gcttcgcatc aaatgcgcca
    13741 ttttgagcga ttacttgggc ttttccttca aaatatggtt ctttttggaa gtttctaatc
    13801 ttttcctgta attgataaat catgtaaagc gttggggttt ggactctgcc taaggaaaaa
    13861 cttcctggta tgcctttttg ctgcaagagt aaactataca gcgggctacc gttcatgccg
    13921 atcaaccaat cggcgatctg gcgtgcttgt gcttcttcaa attttgggta ggtctcttct
    13981 gcatctcgta actgctggaa tccctgataa atggcttctt tttctaagga gttgatccaa
    14041 agtcttttaa atatctttcc atgatcggcg cctgcttgtt gaatgatcgt ccaagctatc
    14101 agttcccctt cacgatcgct atctgtcgca ataataatgg tgtcggccga ttgaagttgc
    14161 tgtttcacca ccttgaattg ctttttctta tctttaggaa catgatagtg ataatgtgta
    14221 gggaaaatag gcaaatgctc taatgaccat tgtttccaat tttcatcgta catatcgggc
    14281 gaatctaact cgactaaatg accaaaacca tacgtgatca cagtttctcc tgaaaacaat
    14341 cgatcttgga tctcaaaata cccatctttt cgggtagctt tagaaaagct atcggcataa
    14401 gccttcgctt gtgacggttt ttctgctaaa ataacggttt tcatcatgac gatttcactc
    14461 cctttcttgc tgtctacctt gttgaaacaa catggcacgt ttttgctttc tgatctcttg
    14521 ttggtagatt tcatgcttca attgatcatt ccaatccttt tttacttcag gtacaaattc
    14581 atgttcatga tttttatagc ctttgtagta ttgttctgct ttataagaga aaagaatctg
    14641 agcattaata tccccttttt cttgataaaa acgatcaaaa tcgtacgtac catccacgcg
    14701 ttcacaagct tttaattctt ttgcgacttc tctacaaata tctttcaaat taatagcttc
    14761 tattgaatcg ttaacagaaa gctgctgacc aaaagacgca tttactttgt gagcggaaac
    14821 caattggttc gttaattgca gattgttttc tgtcttgtgt atggccataa tagcttctgg
    14881 tgtgatcttt tcttcttttg cgacttcttc ataaatgact ttgtattctt ttggcacttg
    14941 ccaatcatta gcgattcctc gttcacaacg tactttctga ttcgtaaatg gatcaactgc
    15001 gcccattaat tgttcttttt cgtagaaaat atgtcctgca cggtcattat ccacacaaat
    15061 ctcgatggat tgaggaaagg cttgtttctt tctcaattca gatactgcct caccaaaata
    15121 atgactgatc acatggtgtt ttaacccttc catcgaaact aaccacgtat cgtttaactg
    15181 atcacgattt agtgcagcat agctaagtaa atcaatacta ctctcaaaaa attttaactg
    15241 cttagggtca ccgatcttta ggttaaagcc atgattcgct gtcgaatttt tatctatatg
    15301 cttatatgtg cctctctcac caaaacgttc ataatcaatg aacgttcctt gataactcgc
    15361 ccctactgtc tcatttgtct gtggatcttt ccataaaaag gcgaccgcat gatctaaacg
    15421 atcgtctcga actaagaaat tttgccgttc atgttttggc tttagttc
//
LOCUS       DAPBAF010000058        15288 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.058, whole genome shotgun sequence.
ACCESSION   DAPBAF010000058 DAPBAF010000000
VERSION     DAPBAF010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15288)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15288)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15288
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.058"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(43..409)
                     /gene="ssrA"
                     /locus_tag="RD451_002386"
     tmRNA           complement(43..409)
                     /gene="ssrA"
                     /locus_tag="RD451_002386"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(580..1353)
                     /locus_tag="RD451_002387"
     CDS             complement(580..1353)
                     /locus_tag="RD451_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDT7567602.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMGNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            1497..1847
                     /locus_tag="RD451_002388"
     CDS             1497..1847
                     /locus_tag="RD451_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HDT7567603.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            1828..2544
                     /locus_tag="RD451_002389"
     CDS             1828..2544
                     /locus_tag="RD451_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7567604.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAVVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            2544..3992
                     /locus_tag="RD451_002390"
     CDS             2544..3992
                     /locus_tag="RD451_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDT7567605.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(4062..4571)
                     /locus_tag="RD451_002391"
     CDS             complement(4062..4571)
                     /locus_tag="RD451_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567606.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(4561..5286)
                     /locus_tag="RD451_002392"
     CDS             complement(4561..5286)
                     /locus_tag="RD451_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567607.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHLQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWHLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
     gene            complement(5509..7629)
                     /locus_tag="RD451_002393"
     CDS             complement(5509..7629)
                     /locus_tag="RD451_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HDT7567608.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLARGKNVIYIHLESFQQFLIDYKLTDENG
                     LQHEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYISAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHNG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            7859..9037
                     /locus_tag="RD451_002394"
     CDS             7859..9037
                     /locus_tag="RD451_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HDT7567609.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIIGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            9053..9811
                     /gene="aroD"
                     /locus_tag="RD451_002395"
     CDS             9053..9811
                     /gene="aroD"
                     /locus_tag="RD451_002395"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HDT7567610.1"
                     /translation="MVRVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFFSMPIITMSMGNLGKISRLVGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            9834..10319
                     /gene="ybaK"
                     /locus_tag="RD451_002396"
     CDS             9834..10319
                     /gene="ybaK"
                     /locus_tag="RD451_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HDT7567611.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSRIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(10390..11643)
                     /locus_tag="RD451_002397"
     CDS             complement(10390..11643)
                     /locus_tag="RD451_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDT7567612.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            11760..13109
                     /gene="gdhA"
                     /locus_tag="RD451_002398"
     CDS             11760..13109
                     /gene="gdhA"
                     /locus_tag="RD451_002398"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HDT7567613.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNVQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            13221..14567
                     /locus_tag="RD451_002399"
     CDS             13221..14567
                     /locus_tag="RD451_002399"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HDT7567614.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(14875..15261)
                     /locus_tag="RD451_002400"
     CDS             complement(14875..15261)
                     /locus_tag="RD451_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HDT7567615.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYPEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
BASE COUNT         4991 a         2737 c         3104 g         4456 t
ORIGIN      
        1 aaataaggat ttaagcatct agcgaaatct gctgaaatct cacaatggag acggcgggag
       61 tcgaacccgc gtccaaacac atcgccactt aaaaatctac gttcatagtc aactcattta
      121 aggattcact ttacagcttg ccgagtgaca ggcattctgt atcgctagtc tgatgttctc
      181 tttttcaact tacagacgga aagttgaaac gtatcccact aaagttagga cccttactcg
      241 agcacatggg cgatgccgag aggatctacg ctaactgttt ttaggcagct aaagcgtaag
      301 agttgttttc gtttttagca gttatattta actgtaacgt ttttacgtag acgtaaccta
      361 cgaaacgcaa ttcaagctcg actgtgcctg tcgaatccgt aacgtccccg ttagctaaca
      421 agggttacgt gtatttttca tacaaaatta gtatagcata tattgggata aattcaataa
      481 aaaagcgaat catatcccat tatttatata ataactgccc ctttcttaag aaaaaataag
      541 cgattttctt aagaaaagag gtagcttcaa aaaaagatct taaatcagat caaaatactt
      601 caatgcgtgg acaattccgc cttctgtatt tttctttgtg ataaaggtag aaagttcttt
      661 taatccgtca taggcgttgc ccatagcgat tttgttgtcg caagcttcca acaaggcaaa
      721 atcattcgga ccatcgccaa atccaaaagt aggaactttt tccagctgaa gttctttttg
      781 cagacgtttg acacctgccc cttttgagat tcctttcttc actgtatcga tcgagtaagg
      841 accattccga taaaaagtta gctcaggaaa atgttcgtga tagtattcgt cacctgattg
      901 agataagatc agcaacatat ttactgtgtt ttctttaaag cctaaaggat caatttccgg
      961 aacatctgaa tgaatgaagt cgtaagcatt gatcattgtt tggctatgac cggtacacca
     1021 gattttctga tcgttatagt aagaaagttc atgaccgttc aactgtacat gatcatacat
     1081 tttttgacat tcttctgaag aaaatgtttg agaatagatt tcttcgccgt ctactcgaat
     1141 gaaagaacca ttcatggtga ccgcagaagt aatgcccgca tcttccatga tagagtggat
     1201 ttctgcttct gtacgtcctg tagcgatgac ggggagaaca ttgttttctt ttaatgcgtt
     1261 catagctttt gccacttcgg gtgtgatttt tgatttcgca tctagtaatg ttccatcaag
     1321 atcaaagaaa gtgattgcac gataatttga cacaaataaa actccttttt tattggaata
     1381 agtttatctt aacaaagaat gaacaaaaga caaacctttc gtgaagaatt cctgaacata
     1441 ttggttcagt caacaattta gagtatacta taagaagaga atttaggagg gaaagaatga
     1501 tttttttcag tattggtatc ttattcttaa taattggcag tctttttcgg attctgccct
     1561 caaaaggaaa tctgcctttt tatgggtatc attcgcctct tgccgcaaaa acagacgctc
     1621 attggcggct ggctcaaaag acaagcggaa actggttttt tcttatgggc ttactgatgg
     1681 cattgatcgg ctattattta aagacatctg ggcatacgaa ttattttctg attgaaatgc
     1741 ttctgctagt atttccaatt atgcctattt ttattatgac agaaaagaaa ttacagaaat
     1801 atgacctgga aactggaggg aacgataatg aatattttaa tgattgaaga taatcaatct
     1861 gtttctgaaa tgatgcagat gtttttctta aatgaaggtt gggaagcaac tttcaagtat
     1921 gatggaaaag aagggctcga tgccttttta gaaaacccac aacattggga tatgattaca
     1981 ctagacctga atttgcccac actggacggt atgctagtag gaagagagat ccgcaaagtt
     2041 tcaagtactg tgccgattat catgctgaca gctagagatt ctgaaagcga tcaggtgatc
     2101 ggcttagaga tgggggcaga tgattatgtc acaaaacctt tcagtcctct gacgcttatt
     2161 gctcgaatga aagctttgca tcgccgtagt gagttggcag aagcaagaga agaagcagta
     2221 gtttcagatg atcattttga tatcgagact agtcatttca agatgaatac gaaaacacga
     2281 gaagcgtatc tggacaaccg gccaattgaa ggactgacgc ctaaagagtt cgatctattg
     2341 tttactttag caaaaaaacc acgtcaagta ttctctcggg agcagttgct tgaattagtc
     2401 tgggattatc agtactttgg tgatgaacgg acagtggacg cccatatcaa gaaattacga
     2461 caaaaaatcg aaaaggtcgg accacaagtc atccaaactg tttggggagt cggctacaaa
     2521 ttcgatgatt ctggtgttgc ctaatgcgtt atttgtatca gcaactctta gctttctgcg
     2581 gaatggtcgc gttgatctta ttgatcgttg gagtttcttt tacacaactg acaaaacaaa
     2641 cgattgaaga aaacaattac cagcaactgt ttggatatgc tgaatcagtt gaaaagacaa
     2701 cgcaaaccta tgccgatacg ctcccgcagt ttagtcaaga tcaggcgttt caaaatgcat
     2761 tgctgctgac agagcaagta ctgacagaac aaaatgtgaa ctttatattt atcgataaaa
     2821 acgaacgtgt catttatccg actaatacag ctttactgaa ttttacctta acagctgatc
     2881 aatggaaaaa tctgaggaat ggacgtcaag aaaaattcac atcgaataaa aatattttag
     2941 gacaagcaca ggcgacctct tacgcacttg tgccatttaa tttgaatcat gaattctatg
     3001 gagcacttgt agttagtcaa cctgcgcgaa atatcgataa cagcgttcgt ccaattacac
     3061 tgaacctgtt caaaggattt attttttcca gtatcgttgc agttattgcc agctatgctt
     3121 ttgcagcatt ccaagttaag cgtatcaatc ggttaaggaa tgcgacgaaa gaagtgacga
     3181 atggtaattt tgatgtacag ctccccgtac atgacaaaga tgaatttgat gagttagcag
     3241 atgatttcaa taaaatgacg aattcattga aagaatctca agcagaaatt gaagaacaag
     3301 aaaatcgtcg aagacaattt atggcagatg cttctcacga gatgagaaca cctcttacga
     3361 caatcaacgg acttctggaa gggttagaat acaatgcaat ccctgaaaat cagcgagaaa
     3421 acgcgattaa attgatgaaa aatgaaacag agcgtctgat ccgtttggtg aatgaaaact
     3481 tggattatga aaaaatccgt acgaatcaaa tcagtatggt cattaaaaaa ttcaatggaa
     3541 cagaaacatt gaaaaatatt gttgcacagt tagaagctaa agcagaagca gcaggagata
     3601 cattgacatt gaaagccgtt gatgatattg atgtttacgc tgattatgac cgatttgtcc
     3661 aaatcatggt caatattatt caaaacgcga tacagtttac tgaaaacggc caaatcacga
     3721 ttactttaga aaaaggctat cttgaaacga tcatcacgat tgaagatacg ggaattggaa
     3781 tgtctgaaca acaaatgaaa agtatctggg atcgttatta taaagtagat ccttcaagaa
     3841 aaaatacaaa atatggtgaa tcaggattag gtttaccaat cgtgcagcaa cttgtacgct
     3901 tgcataaagg aaaattagaa gtagaaagcg aactaggaaa aggaacaaaa ttcgctgttc
     3961 gtttgcctga cgtagaaatc aaaaaagagt aaaaaacaag cggtataaaa gatcatgaat
     4021 cgatcttcta taccgcttgt ttttactata aaatgattga tttagcccgc gggctctaaa
     4081 cgatcaatat aaggactttg agcaatagta gcatcatgag taaagagtaa gataccttga
     4141 ttttcttcat gagctaaata agaaagcaag tggagtagct cttggatctc caatacacta
     4201 agttcatcaa atgtatcttc aataacaata ttgtttcgct tggaaagcaa ggcatgaagt
     4261 aattgcagct ttactttttc aaaagacgtc aactcagctg ccgcacaatt aagcaaggaa
     4321 ggagagatat caagtttttc ttgataggcc aaacgatctt gtttgatttc tttttccggt
     4381 acatccaaca ggacatggtc tttaagattc agataaggaa acatcggcca atttttttgg
     4441 atgatcgcaa aattatccag ttttgcaaca agaacctctt ttttcaagtg ctccaatatt
     4501 ttatgctgtt tttcgagagg acacaaaata acggtcaagt gttcagcatg aatcaaatat
     4561 tcaggtttca ttacgtccag gcctcctact ttgcaaatga tggataaaaa aagtgaaagg
     4621 gaatagacta agaatgagac agcatccact gagcccaata agagtttggg caaatccctt
     4681 aagtatatct gtgaaaaaaa gatcattttg gaaatcgatg gtaaaaaaag tctgttgatc
     4741 catcggaatt gtaagtccgc ttaccgaagt caagatatca cggatatctg gcagttcagt
     4801 agtctttaag acaagaaaat tgatcctttg aagaagcgct tcataaactg actggaagct
     4861 tacgatccac aataaaacca agatacaaca aagaaagaga ggaaagaaca gctgccagaa
     4921 aataaaaagg aataatttgg ttttagaaag accagtcagg tgccaattga tcaattcctg
     4981 cttgttttgc ctgactgaat agtaaaagaa aaagataaaa aggaaggcaa atagaaaaaa
     5041 taaactgaat atgcctttta tataaaatcg gctagctaat tctaaagccg gaagaagctc
     5101 tgtagatgca gaagcgccaa taaatgaaag ccgatcttgg acttgattgg ctaaagccga
     5161 ttgcaaatgg taaagagtca ggcatgctat caataaaaaa gcagaaaagc ttgaaaataa
     5221 acaatagagt attgtctgct ttttgtaata aattaatcga gcagtagcat agcggattat
     5281 tttcatactt ttcacctcta taaaaagtat agaaaatgaa tatgaataaa gtatgaaatt
     5341 cctttagtga aatcacgaat taaaaccaga aaatattttg taaaaagcaa gaggttgtga
     5401 agaagctgcc ctattctatt accgtagatg caagcttttg aacactgttt attcgaaaag
     5461 aggagcagcg acaataattt tgtcgctgct ccttttaaat ttattttatc attcggaaga
     5521 acttgtggtc gttccgtgaa gttcttggta cgtttgcgtt ttataaagat caacagttga
     5581 ttgtccgttg tgttcactaa agacactagt tgacttgtca ccaagagatt tttcagcttc
     5641 ttttaatttc tctaagccat tcttgtagtc ataatcactg gtatcaattg ggtctaatcc
     5701 actattcgta tagaaccgaa gaagatcacc attattgatt tggtcagaaa cagctaactg
     5761 tttatcaact ttttctttca gtgaatcaat ttcattctgt acttcctcag taggttcagt
     5821 aatagcttca ccagtttcgt tactatagat cgtaccaccg tagtaagtat attttggtgt
     5881 aacaaaatca ccatcacgga aagaaacaag ctgttcatga tctttcgaga atagatcttg
     5941 tcctaactga atataatttt ttgtatctac acctagtaag tgaagtaatg taggcaaggc
     6001 atcaacttgt ccgccgtaag tgtgattgat tccgccctgt gtttgtccag ggatatggat
     6061 catataaggg acacgctgca tttgtgcatt gtcgtagttt gtccaagtag aacttgtttt
     6121 tccaactaat tcagctagat ttttatttct tgaattcgag acaccgtaat ggtcaccgta
     6181 aaggacgatg actgaattat catacaagcc gctttctttc aaataattga agaattcttg
     6241 tacggcggta tctaaataat tggctgtcgc aaagtaaccg ttgatcgttt catcatttgt
     6301 attggctaac gggaatcctg cttcgtcatt ggtgaatttt gaataaggat aatggttaga
     6361 tacagcaatg aattttgaat aaaatggttg ttgcagacgt tccaagtatt gtacggattg
     6421 ttggaaaaat ggtttatcat gcaacccgta ttggaacgaa ttgtcatcat taacatcata
     6481 ataagaagaa tcaaagaaat aatcatatcc taaattcttg tatgtctcgt ttcgattcca
     6541 gaatgtacca gcgttcccat ggaataccgc actaatgtaa ccttgtgttt gacttaaaat
     6601 atcaggtgca gcttggaaag tattttttcc gcctaattgt gtgaacaagg agccttgatt
     6661 caagccaaac aatgaatttt ccatcagcgt ttccgcatcg cttgtttttc ctgcttttac
     6721 ttgatggaaa aagttgtcaa aactgaacgt gctgttgctg tggtaaagac tattgatgaa
     6781 aggtgtaact tcatgctgga gaccattctc atctgtcaat ttataatcga tcaggaattg
     6841 ctggaagctt tctaaatgga tataaatcac attttttcct ctagcgagcc cgaacaaatc
     6901 gtcatttggt gctgcataat gttcttttac ataattttct acttctttca tatcattggg
     6961 acttgcttct gcccgcactt ggtttgtctg gtaagtttga acaccgtcat aaaccatgaa
     7021 agcattcaag ccaagatatt tgaccaaata atcacgagag aatgttcgag tcagcaattc
     7081 tggacgatca gcttccgcca taaaaagatt tcctgagaaa atcataactg ctaatgtaga
     7141 gatcgcaaaa gccattcttg ctcggatcgg gcgagggtcc aacttgattt tttttgcaat
     7201 cagcagaaca gtcaagataa taaaatcgat ccaatagatc acatcatatg ggcgaaacag
     7261 tcgaatggca ctttctccca gaccactcgc tactttccca gcacctaaaa tcgtgttgat
     7321 cgtaatgaag tccgtgaatt ctcgataata agtgacattc gaaaaaacaa gcaatgtcaa
     7381 aagaaaataa atgaccatca tcgtgatata agcaactcta gggcgtctga tataaagagc
     7441 aattccaagt aataacaatg tagttgcaat agggttgata aacaagataa agtattgaat
     7501 gccactttcg attccgagat ggaaatcaac taaataggca aaaatcgttt tcaaccaaag
     7561 taaaacgact agtaaagaaa aaaatccgag cctcttattc aaaaaggcag gtgtttttat
     7621 acatttcaag ataatcttcc tttctgcact tcttaatcac agaagtgtcc tgaaaccatg
     7681 ttacacagct cacttattct catttatttt actagtatga caatatagtg tcaattgaaa
     7741 ccagaagttt atgctgtttc attaaggttt tctttaagct tcatgaaaaa atgagcagta
     7801 agacaagtcc tatgtttttt gttatacttg ggaagagaaa gctaaagcag gtgaaggaat
     7861 gaaagtaaaa gtaaaaaaaa gagcaagcaa tcgattgaaa aaaggatatc cactgatcca
     7921 aaaagaagac cttgctcatc cccaaaaaga aaccacgcaa tgggtggaat tagttgattc
     7981 gcaaaaccaa tttatcgcaa aaggatatct aggaaagcag aataagggaa tcggttgggt
     8041 attgagccag cagaacatcc catttgatca atcttttttt gaagaatttt ttgtgaagtc
     8101 aaaagaaaaa agaactttct ttttttcaga tgattctact accgcttttc gtatattcaa
     8161 tggagaagga gacgggatcg gcggtctgat tgttgattat tatgcaggtt atgctgtttt
     8221 ttcttggtat aacgaaacgt tatatgcaca tcgtgaatta ttgattcaag cttttcgtga
     8281 aatctacccg gaaatcatag gaggctatga gaaaattcga tttgaatcag taaatctgcc
     8341 tgagagccag ttcatttacg gaaaagaggc accggaaccc ttgatcgtaa aagaaaacgg
     8401 agtaaaattt gccgtttatt taaatgaagg attaatgact gggatctttt tagaccaaaa
     8461 agaagtacgg ggatcattag cagaaggttt cgcttctggg aaaacagttt tgaacatgtt
     8521 tagttatacc ggcgcctttt ctgttgctgc cgcaatggga ggggcaatcg aaacaacaag
     8581 tgtcgatcta gcaaaacgca gtttaaaaaa aacacaggaa cagtttgaag tgaatggttt
     8641 ggatgtcgat cagcaaaaaa tcattgttat ggacgtattc gagtatttca aatacgccaa
     8701 aagaaaacaa tttttatatg acatgattgt attggatcca ccaagttttg ccagaaataa
     8761 gaaaaaagtc tttcgcgtag caaaagatta tggggaactg gtcaaggata gtctggatat
     8821 tttagcagaa gacgggatac ttattgcgtc tacaaatgct gcgaatgtct cgatagaaca
     8881 attccaaaca atgattgaag aggaattcca tgccaaaaat gtttcttttg aacaacttgc
     8941 tttatatcgt ctgccaaaag atttccagac gacggatacc tttttagaag gcaattatct
     9001 gaaagtgttt gtttatcaaa ttaaaaataa ccattagaag gagcgatgca gaatggttcg
     9061 ggtaaaggga ttgaatatag gaagcggtag accaaagatt tgtgcgcctc ttatcggggc
     9121 cgtccgagag gaagtattac gtgaagcagt tcttgcacgt gaagcagggg ccgatttagt
     9181 cgaatggcga gtcgatcatt atcgtgaagt tttttctttt gatgaagtag cagaaacatt
     9241 ggttcttatc catgagatgc ttgatggact gccgttatta tttacgtttc gtaccttagc
     9301 tgaaggcgga gaacaagaca tatcgatccg tcagtatcgc gacctttatg aacatgtgat
     9361 acacacagga ttagtagata tggtcgatat cgagttgttc aaagtagaaa gtctaggaaa
     9421 aagactgata gaggaaatca agtctttaaa cattccttta attatcagta gtcatgattt
     9481 taaagaaaca ccagcagacc ctgtcttgct ttaccgattg aatgttatgg aacattttgg
     9541 agccgatatc ggaaaactgg cagtaactcc caataatgaa cgagatgttt tgcggttgat
     9601 ggagttgact agacgggcaa atgctttttt ctccatgcct attattacga tgtccatggg
     9661 aaatcttggt aaaatttctc gtctggttgg cggaacgacg ggttccgtta tgacatttgg
     9721 ttccttaagc agcgattcta cttctgctcc aggacaatta ccggtcaaag cattgaagca
     9781 aattattcaa ttattaaatg aaccgttgta gaacaagttt gaggtgatat tttttggcaa
     9841 agaaaaaaat agtaaaaacg aatgcaatcc gtatggtcga acaaaaaaag attccctata
     9901 cagagcacga atatgagtgg gacgaaagcc acctaagtgc gtcatcggtc gctgaacagc
     9961 ttccagaaag ccaatctcgt atatttaaaa cactggttgc tgtgggcaat gtgacggggc
    10021 ctcttgttgc tgtgataccg ggagaagccg aattgaatct aaaaaaatta gcaaaagttt
    10081 cagggaataa aaaagtagaa atgctccatt taaaagattt ggaagcaacg accggataca
    10141 tacgtggtgg ctgctcgcct ataggtatga aaaaactatt tcctacttat ttagatcaaa
    10201 ttgcagaaag ctatgaacaa atcattgtct cggctggcag aagagggcta cagatggagt
    10261 tagcacctca agatatctgt gcattaacga gcggacaatt tgcagatata aaacaataaa
    10321 tcatacgtat aaaagaaaga aggaggccgg gatgttgttt gtccagtctc cttctttctt
    10381 ttttatacat tatgctcttt gcccggcatt cattcctgct acatgccctg tagcgaaagc
    10441 cgctgtgata ttaaagccgc cagtataacc attgacatcc agtaattctc ccgcaaaata
    10501 cagaccatca atgattttac tctccaatgt tttaggataa atttccttta gagaaacccc
    10561 tccgccagtt acaaatgatt tctcaatagg aaaagttttg ttgattgata gcttaaactc
    10621 tttgcatagt tgaacaaaat cttgaatttg tttttgagag gcttgttgtc ctgtcagatg
    10681 atccatttca agccgctcaa gaaagaaaac taacaatcgc tcaggcaata taccatgcca
    10741 agcattgacc aagttctttt tggttgcttt acttttttct gtcaatatat gaataagctc
    10801 ttgtttggtt tgtgtaggga aacaatccag agaaagtgtc actggttctc ccgttttctc
    10861 taattcttta ttgacaaaac ttgaacaacg cagtgcagcc ggaccagaaa taccgaaatg
    10921 ggtgaaaagt aaatccatcg tatgttcagt caatacacga ccttttttat ttaaaacgcg
    10981 taaagtgatg tcttgtaaag aaagcccttg aagtgttttc tcctgaatat acggttcatc
    11041 cgatatcaag ggggactctg tcgcataaag aggcgtcacc gtgtgaccca ctcgcttcac
    11101 gatcttgtac ccatctccag tagaaccagt agatggataa gtccgtccac cagttgttaa
    11161 gataatggca ggagcatgga actcttcgaa ttccgtgcgt ataccgtaaa ttttatgttc
    11221 tttgtggatc aatttctcta ctcgagtaga gaatagaagc gtcacatcta gttctttcag
    11281 acgattgagc aatgcttcga taatcgtttt tgatttattt gttacaggaa acatccgtcc
    11341 atgatcctct tcttttaaat gtacgccttg tgattcaaag aagttcatga tatcgaaatt
    11401 attccattgc gcaaacgtac tatataaaaa ctttccattt ccaggaatat gtgcaatcaa
    11461 atcatcaaca ggacgattgt tcgtaacatt gcaccgacca ccacctgtca tcagtagttt
    11521 ttttcctgct tttttgtttt tttcgatcaa gagtacgcgt gcgccttgtt cagctgcact
    11581 gatcgctgcc atcatcccgc ttgttccagc gccgactacg atcacatcat acagtttttc
    11641 cattccctca cctcaaggaa agtgtagcat atctgaagaa agaaaacaga aaaaaatgtt
    11701 ttgagccaaa agagaaaatg agctaaaatg agggaagata agcaaaggag cgtggaacga
    11761 tgacaaacgc aacagaatat gttcaagcaa ttcaagaaaa gctacatcaa aaggatcaag
    11821 ggcaagaaga atttttacaa gcaatcgatg aattcatgcc cacggttatg tcttttttgg
    11881 acactcatcc cgaatatatc gaaaagaata tcttagaact tttaacggaa ccagaaagag
    11941 ttattcaatt tcgagtgcct tggcaagatg atgaaggaaa ctggcgagta aatagagggt
    12001 accgtatcca atacaactca gctatcggcc cttataaagg tggattgcgc ttccatccta
    12061 gtgtcaatct aagtatcttg aaatttttgg cttttgaaca gattttcaag aatagtttaa
    12121 ccggtctgcc aatcggtgga ggaaaaggcg gaagtgactt cgatcctaaa ggaaaatctg
    12181 ataatgagat catgcgtttt tgtcaaagtt tcatgctgga attgtcaaaa catatcggcc
    12241 catcgattga tgttcctgcg ggagatatcg gtgtaggagc tagagaaatc ggctatttgt
    12301 tcggcgaata taaacgattg aaaaaatatg atactggtgt gttgacaggt aaacctttgg
    12361 atttttgggg aagtaagata cgtacggaag ctactggtta tggattagtg tattatgtca
    12421 aacatctatt gaacgaagaa aaagattcat ttaatcaaaa aacagttttt gtttccggaa
    12481 gcgggaatgt agccatttat gcaatcgaaa aagtgcaaga gctaggcggg aaagttgtta
    12541 catgttcaga ttctagcggg tacatctatg atccagaagg aatagatgtg aaactattga
    12601 aagaagtcaa agaaatcaat agacaacgtt tgacggaata cgcaaaccaa cgtccttctg
    12661 ctatttatca tgctggagaa tctgtttgga cattgaaaga aaaagcggat atcgctttgc
    12721 catgtgctac tcaaaatgaa atagacgaaa gcttggccga aatcttagta gaaaatggga
    12781 tcaaaatcgt agcagaaggc gctaatatgc catgtacagt aaaagctgtt tctgttcttc
    12841 atgaagcagg cgtgtggtat tgtccaggaa aagctgctaa tgctggagga gtagcagtat
    12901 ctgctttaga aatgagtcag aacgtccagc gattgacttg ggaaagagag caagtggatg
    12961 agcagctgga tcaaatcatg gaaacgattt accatacgtg tcgccaaaca gcagccgagt
    13021 acggcgacga aaaaaatctg cttcttggag caaatgttgc tggatttgaa aaagttgcca
    13081 aagcaatggc agcagaaggt ttagtttgaa aaatgaaact ttcttggaaa tattgtcagc
    13141 attttgttta tttgcttgaa aaataataaa aaaaaacgta aagtattacc tgtagagtaa
    13201 acctataagg aggagaacaa atggcacaca ttcattttga ctattcaaaa gtagcaccgt
    13261 ttgtcaacga acaagagtta gggtacatgc aaagccaagt aacagcagcc cacaacgaat
    13321 tacgggaagg tactggcgca ggaagcgact tccgcggctg gatcgattta ccaacgaact
    13381 atgacaaaga agaatttgca cgtatcaaag aagcagctaa aaaaatccaa tctgattctg
    13441 aagtattagt tgttatcggt atcggtggtt cttatttagg cgctcgtgca gcgatcgact
    13501 tcttgaatca cacattcttc aatttattag atagcaacac aagaaaagca ccacaaatct
    13561 tctttgccgg aaattcaatc agctcaacat atattgctga cttgatcgaa gtaatcggtg
    13621 atcgcgactt ttcagtaaac gttatttcaa aatctggaac aactactgaa ccagcgattg
    13681 cgttccgtgt attcaaagag cttcttgtta agaaatatgg acaagaagaa gcaaacaaac
    13741 gtatctacgc tacaacagat aaagcaaaag gtgcagttaa agtagaagca gatgcagaag
    13801 gttgggaaac tttcgtgatt cctgatgaca tcggcggacg tttctctgta ttaactgctg
    13861 ttggtttgtt accaatcgct gttagtggtg cagatatcga tgcattgatg caaggtgccg
    13921 ctgatgcaag caaagcatac tcaagcgaca aactagaaga aaacgaagct taccaatacg
    13981 cagcaatgcg caacattctt taccgtaaag gcaaagtaac tgagttgttg atcaactatg
    14041 aaccaggaat gcaatacttc tcagaatggt ggaaacaatt gtatggtgaa tctgaaggaa
    14101 aagaccaaaa aggcatctat ccttcaagcg caaacttctc aactgatttg cactctttag
    14161 gacaattcat ccaagaagga cgtcgcaata tttttgaaac agttgtgaag gttgaaaaac
    14221 ctcgtaaatc aatcacaatt cctgaacaag cagaagattt agacggtcta ggctacttgc
    14281 aaggaaaaga agtggacttc gtaaatacaa aagcatttga aggaacattg cttgctcata
    14341 cagacggtga cgtgcctaac ttgctagtca aaattccaga aatggatgct tatacattgg
    14401 gttatacaat gtacttcttt gaaattgctg taggtatttc aggttacttg aatggaatca
    14461 acccattcga ccaaccaggt gtagaagctt acaagaaaaa catgttcgca cttctaggca
    14521 aaccaggctt tgaagatctt gctaaagaat tgaacgaacg cctgtaagat aagggttttt
    14581 cgctagattt aaataatcag tgatagaaac atgttcgctt taaaatgaaa actggtaccc
    14641 atttaggtac tcaaacatac tgcatcgttt attcagaata aggggctgtg acaagacgtt
    14701 tgtcacagtc ccttgtttgt atagaaatcg attgattgcc ttgctcttta gtttgtttta
    14761 ggactttaag aacagtgagg ctgacttcga aggttaattc tgtttttttg ttttctagaa
    14821 tcagtaagca aaaaagcact cacttcgagt gcttttttgc gatatattct tagcttaaga
    14881 taggcctaat ttttctttta cagatgaggg taccttatcg ctggtaatta cttttttctc
    14941 tatgatccgc ttttcgcttg ctttcaactg caagatcgtt ccttcggggt aagcagaacc
    15001 attggcagag tcaccagaag taatgacatc gaaatctaac tgtctttttt caccgttttc
    15061 agcataagca tctacgttgt atttaaaacc tcttccaatt acttccccat tatctgcttt
    15121 gatatcagtt tctgcaggca ttggagcttt gactaccgca taataatctt tacctacata
    15181 agtagactga tagtagtccc aacctttcca tcctataaaa gcaatcaata tgataacgat
    15241 caaccctaaa atttttttca tgaaagatct ccttttttat ttttatta
//
LOCUS       DAPBAF010000059        14624 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.059, whole genome shotgun sequence.
ACCESSION   DAPBAF010000059 DAPBAF010000000
VERSION     DAPBAF010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14624)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14624)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14624
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.059"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            3..815
                     /locus_tag="RD451_002401"
     CDS             3..815
                     /locus_tag="RD451_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HDT7567616.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            812..1612
                     /locus_tag="RD451_002402"
     CDS             812..1612
                     /locus_tag="RD451_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HDT7567617.1"
                     /translation="MKQRVITAAVALVLFIPIIWIGGIAVELTAAILAVVGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            1773..3041
                     /gene="rseP"
                     /locus_tag="RD451_002403"
     CDS             1773..3041
                     /gene="rseP"
                     /locus_tag="RD451_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HDT7567618.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAIVLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPGKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            3109..4818
                     /locus_tag="RD451_002404"
     CDS             3109..4818
                     /locus_tag="RD451_002404"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HDT7567619.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPERDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTSLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELANTLPILLN
                     QGE"
     gene            5030..9388
                     /locus_tag="RD451_002405"
     CDS             5030..9388
                     /locus_tag="RD451_002405"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HDT7567620.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIH
                     IQLGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSF
                     IVKKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYA
                     PEGEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGK
                     KAGVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAV
                     KMYKGNVIESFDEFIDPGHPLSRTTVDLTGITDGMVRGSKSEEEVLRMFLEFSKDTIL
                     VAHNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSL
                     EQHHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILA
                     KNQAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKG
                     VEEARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVAT
                     GNVHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEI
                     VVENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRL
                     KKELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAP
                     HYYCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPD
                     IDLNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSA
                     EVDRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHS
                     IHDNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIY
                     SKTGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDAT
                     LAEVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVP
                     DWYIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMC
                     KGKDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFV
                     IEGDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGV
                     LKDLPDENQLSLFDML"
     gene            9533..10006
                     /gene="rimP"
                     /locus_tag="RD451_002406"
     CDS             9533..10006
                     /gene="rimP"
                     /locus_tag="RD451_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HDT7567621.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            10029..11204
                     /gene="nusA"
                     /locus_tag="RD451_002407"
     CDS             10029..11204
                     /gene="nusA"
                     /locus_tag="RD451_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HDT7567622.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            11226..11519
                     /locus_tag="RD451_002408"
     CDS             11226..11519
                     /locus_tag="RD451_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HDT7567623.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            11516..11827
                     /locus_tag="RD451_002409"
     CDS             11516..11827
                     /locus_tag="RD451_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HDT7567624.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            11840..14146
                     /gene="infB"
                     /locus_tag="RD451_002410"
     CDS             11840..14146
                     /gene="infB"
                     /locus_tag="RD451_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HDT7567625.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSNDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            14173..14520
                     /gene="rbfA"
                     /locus_tag="RD451_002411"
     CDS             14173..14520
                     /gene="rbfA"
                     /locus_tag="RD451_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HDT7567626.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKTAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
BASE COUNT         4982 a         2598 c         3255 g         3789 t
ORIGIN      
        1 gaatgttacg tttttttccg caaaaaaaca aatatattca agaaaaaagc gaatttcaat
       61 ttaataccga tggaccaatt cctcagcaca ttgccatcat catggacggc aatggtcgtt
      121 gggcgcaaaa ccgtcgtttg ccacgagttg ctggccataa agaaggcatg gaaacagtaa
      181 agaaagtcac aaaaaaagca tcaaggcttg gagtgaaagt gttgacgctt tatgcctttt
      241 cgactgaaaa ctggaagcga ccaaaagatg aagtaagttt tctcatgcaa ctacctgtcg
      301 acttctttga tacgttcgta ccagaattga ttaaagaaaa tgtcaaagtt catgtcatgg
      361 gttatgaaaa cgtattgcca gaacatacgc aagatgctgt aagacgtgca attgagcaaa
      421 caaaaaacaa tactggaatg gtattgaatt ttgctttgaa ttatggaagt agagcagaga
      481 tcgtgactgc tgtccaagaa attgccgaag aagtagcaaa aggagaaata cacgcagaag
      541 aaatcgatga tgaattgatt gctaagcatt taatgacagg tttcttgcct aaagagttac
      601 aagatcctga gctgatgatc cgtacaagtg gagaagagcg aattagtaat tttctgttat
      661 ggcagatcgc atatagtgag ctgtatttta caaaagcgct ttggcctgat tttgatggtg
      721 cgcatcttga agaagcaatc gcctcttatc aaaatcgaga ccgtcgattc ggcggtgtaa
      781 aaaaaacaga agatgagaaa ggggatcagt catgaaacaa cgtgtgatca cagcagctgt
      841 ggcgctagtc ttgtttattc cgattatatg gatcggaggc atagcggttg agcttacagc
      901 agcaatctta gcggtagtag gagtttacga gctgttccgg atgaaaggat tgacactctt
      961 aagttttgaa ggagttttat ccgccgttgg tgcagtgtta cttgttttgc caaaagaaag
     1021 atggtttttc tttcttccag agaatgtaag tacatttatg ttattttatc ttatagttat
     1081 gattctttta ggaacatcag ttatttctaa aaatacgtat acgattgatg aagcaggttt
     1141 tcctgtgctt gtcagcttgt atgtgggaat aggtttccag aattttgtca atgcacgaac
     1201 agaaagcttg gctgttttga tatttggtct atttattgtt tgggcaactg atatcggagc
     1261 atatatggtt ggtcgacgtt atggtcagca taagttaagt cctgatattt cgcccaacaa
     1321 aacgattgaa ggtgcgctcg gtggtatcgg tagtgctgtt gtagtcgcat ttctttattt
     1381 attgctatac ccagcaaaag aactattcaa tcatggtatg tttgtcatgc ttctgatgac
     1441 gattattttt tcagcagtcg gacaatttgg tgatttggtc gaatctgcaa tcaaacgtca
     1501 ttatgatgtg aaagactcgg gaaatatctt accaggccat ggtggaatct tagaccgttt
     1561 cgacagtttg ctgtttgtat ttcctatcat gcatttattt ggcattattt agtaagtata
     1621 cctgcgtttc tttgtgaatt tcataaaaga cgcaggtttt tatttttcat tatattgata
     1681 ctattggtgt ctttggtata ctatggtaaa attatagtgt tttatcgttg ttttataaaa
     1741 aacacaaaaa acaagtaaag gagaaaaaag ctatgaaaac gattctgaca tttatcatcg
     1801 tttttggtat attagtgatt gttcatgagt ttggtcattt cttctttgcg aaacgatcag
     1861 gaatcctcgt ccgcgaattt gctatcggta tgggtccgaa aatttatggg catcaagcaa
     1921 aagacgggac aacatatacg cttcgcctat tacctattgg cggttatgtt cgaatggcag
     1981 gcaatgggga tgatgaaaca gaaatggcac caggaatgcc tctttctctt ttactaaatt
     2041 ctgacggcat cgtagagaag ataaatttaa gtaagaaaat ccaattgaca aatgctatcc
     2101 cgatggaatt gagccgttat gatttagaag atgagctgac tatcactggt tatgtgaatg
     2161 gagacgaaac agaagtagta acctaccctg ttgatcacga tgcgacgatt attgaaaacg
     2221 acggaacaga aatcagaatt gcgccaaaag acgtacagtt ccaatcggct aaattgtggc
     2281 agcgtatgct gaccaacttt gctggaccca tgaataactt tattttggca atcgtgttat
     2341 tcatcattct ggcatttatg caaggtggtg ttcaagtgac gaacactaat cgcgtaggag
     2401 agatcatgcc taatggagct gcggcagaag caggcttaaa agaaaatgat gaggtagtca
     2461 gtgtggacgg aaaagaaatc cattcatgga atgatctgac aacagtcatt acgaaaaatc
     2521 caggtaaaac attagacttt aagatcgaac gagaaggtca ggtgcaatct gtcgacgtga
     2581 caccgaaatc tgtagagtca aatggcgaaa aagttggcca acttggtata aaagccccaa
     2641 tgaatacagg ttttatggat aagatcattg gagggacgcg tcaagctttc agcggttcat
     2701 tggaaatttt caaagcctta ggatcactat ttacaggttt cagtttagat aaattaggcg
     2761 gacctgtcat gatgtaccaa ttgtcttcag aagcagcaaa tcaaggtgta acaactgtta
     2821 ttagtttgat ggcgcttctt tcaatgaatc tcggaatcgt caatctgctt ccgattcctg
     2881 ccttagatgg cgggaaatta gtcttgaata tttttgaagg gattcgcggg aaaccattaa
     2941 gtcaagaaaa agaaggaata ttgacattag ctggctttgg atttttaatg ttgttgatgg
     3001 tgctagttac atggaacgat attcaacgat tctttttcta gaaaaagttg acaaataggg
     3061 tataataaca aacgataact attttgagga aataaaggag tatatagaat gagacaatca
     3121 aaaatgttga ttccaacatt acgcgaagtt ccaaatgatg cagaagtatt aagccatcaa
     3181 atcttgctaa gagctggata tatccgccaa gtatcagcgg gtatttattc atatctgcca
     3241 ttagcaaatc gtgtattgga aaaactgaaa cgcattatgc gggaagaatt tgaaaaaatc
     3301 ggagcggtag aaatgctgat gcctgccatc ttgccagcag aactttggga agaatccggg
     3361 cgttacgaaa catatggacc aaacttgtat cgtttcaaag accgcaatga tcgaaaaatg
     3421 atccttggac caactcacga agaaactttt actgatttga tgcgtaatga aatcaattca
     3481 tataagaaat tacctttaaa tctttatcaa atccaaccta aatatcgtga cgaaaaacga
     3541 cctcgcttcg gtttgcttcg cggaagagag tttatcatga aagatgcata ttctttccat
     3601 gcaacggaag aaagtttgga cgagacatat aaagattacg aaaaagccta taccgaagta
     3661 ttcaagcgtt gtggcttaga atttcgctcg atcatcggag acggcggcgc aatgggcggg
     3721 aaagactcaa aggaattcat ggcgatctca gaaatcgggg aggatacgat ctgttattcg
     3781 actgaaagtg attatgctgc aaacttggag atggctacaa gctactatgt atcaaaaaaa
     3841 tcgcatgaaa cacagcttga attggagaaa gtagctacac ctaacgtaaa atcaattgac
     3901 gaagtagcag atttcttttc tgttgaacct caaaaaatca tcaagtctgt attgttcatt
     3961 gcggatgaac aacctgtcct tgttttggta cgtggagacc atgaagtcaa tgacgtaaaa
     4021 ctgaaaaact ttttatctgc tgacttttta gaagaagcaa cagaagaaga agcacaaaaa
     4081 tatctaggtg ctgagtttgg ttctgtcgga ccagtcggtg tttcagatga cgtaaaagta
     4141 tatgcagacc gttatgtcca agatttagcg aatgccatta ctggagcgaa cgaaacagga
     4201 ttccactata aaaatgtgaa tccagaacgc gatttcactg tgctttctta tgaagatctt
     4261 cgttttgtac aagaaggaga tccttcacca gacaacaacg gtgttcttgc ctttactcga
     4321 ggaatcgaaa tcggacatat attcaaaatc ggcactcgtt acagtgaatc tatgggagca
     4381 actgtactag acgaaaatgg acgagaaaaa tttgtgatta tgggctgtta tggtatcggt
     4441 gtaagtcgtt tattatcagc aatcgtagaa caacattcag atgaacaagg aatcaattgg
     4501 ccaaaaggaa ttgcgccatt tgatctgcat atcgtccaaa tgaatctaaa agacgaatac
     4561 caaacaagcc tgacgaatga actagaagaa gcgatgacaa aagctggcta tgaagtactg
     4621 gttgatgaca gaaatgaacg cgcaggagtg aaattcgcgg attctgattt gattggctgt
     4681 ccaatcagaa tcactgtcgg taaaaaagca gtggatggaa tcgtagaagt gaaaatcaag
     4741 aaaactggcg aaatggttga agtacgtaaa gaagaattgg cgaatacttt accaatcctc
     4801 ttgaaccaag gcgaataata agcgttaaaa cacagaaaat aaaaatagct gaatcagctg
     4861 tttttgacaa tctgatgatt cgcttttaaa attggaactg cgatttgaat cgcagttcca
     4921 attttttaat gtaaaactca gaaaaaacga gtatactaaa aggtactgaa aaagaagagg
     4981 ataagatgcg atcaattgca ttgtttctca tcagaaaggg cgtatatctt tgtcagaaaa
     5041 acgagattta tttgaaaaac tgttggaaca aatccaacta gaggaagcag aaaaaaatca
     5101 tccactgctt actgctggtg aaatggatag tgtagtggtc catcgtaaat cgcgtttatg
     5161 ggaatttacg ctacattttt ccaaaatttt gcctattatg ctatatcggt cattgactca
     5221 gcatctgact atcgctttta aagatattgc acaagtcaaa ctgaatatct tagcagatga
     5281 ccagacattc gatgaacagc tcttgcaaga ttactgggcc caagctttgg aaaatcagca
     5341 atgcgataca ccactagcac agcaagtatt gaaaacgcag gtacctgtga taaaagatcg
     5401 taaagtcatc ttgccaatcg acagtacagg agctatttct tatttgaagc aacaatactt
     5461 gccattagta gaagagttgt tcgtcagtta cggattccca aaatttcgta tcgaaccaga
     5521 agtggatgag cagcaagcgg aacgagtatt gaaacttttt gaagaacgca aacaagaaca
     5581 ggcagaagcc tttatgaagc aagcagctga aagtctagtt gtccacgaac aaaagaaaaa
     5641 ggaaagaaaa gagcaatcgc cagctcttga aggacccatc cacatccagc taggacgaaa
     5701 tattccagcc gatgaaccaa cgacaccaat gatcagtatc gttgaagaag aacgaagagt
     5761 cacacttgag gggtacgtat tcgacaaaga agtcagagaa ctacgttcaa aacgcaagat
     5821 cttgactttg aaaatcacag attatacttc atcatttatc gtcaaaaaat tctcgaacgg
     5881 cgaaaaagat gaacaagtat ttgatgcgat cagtgtcggt agctggttaa aggtacgagg
     5941 aagtattcaa gaagatacgt ttgtccgtga tttggtcatg aatgcgcaag atatcataga
     6001 agtcaaacat acacctcgca aagattatgc tcctgaaggg gaaaaacgag tagagcttca
     6061 tgttcatagc aatatgagta cgatggatgc aacaaacagc atctctgatc ttgtggcaca
     6121 agcagggaaa tggggacacc gagctatcgc cattacagac cacggtggtg cgcaagcctt
     6181 tccggaagca catagtgctg gaaaaaaagc aggtgtgaaa atcttatacg gcgtggaagc
     6241 gaatgtcgta gatgatggtg tcccaattgc ttataatgat gcacatgaag cattgagtga
     6301 agccacatat gtcgtatttg acgtggaaac gacaggattg tctgcagtat atgacacgat
     6361 catcgagcta gccgcagtca aaatgtataa aggaaatgtg atcgaaagct ttgatgaatt
     6421 tatcgatcca ggacatcctt tgtcacgaac aacggtagat ctgactggta tcacggatgg
     6481 aatggttcga ggatcaaagt cggaagaaga agtattgcgg atgttccttg aattttcaaa
     6541 agatacaatt ttggtagccc acaacgcggc ttttgatatg gggttcttga atactagcta
     6601 cgcaaggtat ggtattcctg aagcggccaa tccagtcatt gatacgttgg aattagctag
     6661 atatctgtat cctcaattca aacgtttcgg attaggtgtg ttatctaaaa aatttggtgt
     6721 cagcttggaa cagcatcacc gagcaatcta tgatgctgaa gcaactggtc acttagcatg
     6781 gatctttgtg aaagaggcaa tggacaatca taacatgctt tatcatgatc agctaaatga
     6841 gcatatcgga gaaggagatt cttacaaaag ggctcgacct ttccatgtaa cgattttagc
     6901 aaaaaatcag gcaggactga aagatttgtt caaactgatt tcaatgtcga atgtcgaata
     6961 cttcgaacgc gtcccacgaa taccacgctc ccaattgaaa aagatgcgtg aaaatctatt
     7021 gatcggctca gcttgtgata agggagaaat attcgaagcc atgatgcaaa aaggggtaga
     7081 agaggcaaga aaccgagcaa aattctacga ttatattgaa gttatgccaa aagcggtcta
     7141 tgcgcctttg atcgagcaag aattggtaaa aaatgaacat gatttggaag aaattatcca
     7201 aaatttggta gaaatcggaa aaagtttgga taaaatcgtt gttgcaacag gtaatgtaca
     7261 ttatctgaac gaagaagatg ccatttaccg aaaaattttg atcaattcta tgggcggagc
     7321 gaatccgttg aatcgtcata gtttgccgga tgtccatttc cgaacaaccg atgagatgct
     7381 aactgcattt cactttttag gggaagaaac agcgaaagag atcgtagtag aaaatacgaa
     7441 taaaatcgca gatatctgcg aagaagtgat tccagtcaaa gatgaacttt atacaccgaa
     7501 gattccaggt tcagaagatg aaatatcaga attgagttac acaaaagcaa aacaaatgta
     7561 cggagatccg ttacctgaga tcattcaaaa acgattaaaa aaagagttga attctattaa
     7621 tggtaatggc ttctcggtta tttatctgat cgcccaaaaa ctagtgcata aaagtaatga
     7681 agatggctat ctagtaggtt cacgtggctc tgttggctct agctttgttg cgacgatgac
     7741 aggaatcact gaagttaatc cgttagcccc tcattattat tgtccagagt gccaatattc
     7801 cgagtttttt gaagatggta cgtatggttc tggatttgac atgccagaaa aacaatgtcc
     7861 aaaatgtggt gcacgcttaa acaaagacgg tcatgatatt ccatttgaga catttttagg
     7921 attccatgga gacaaagtgc ccgatattga tttgaacttc tcaggtgatt atcaagcaga
     7981 agcccataac tatacgaaag tattgtttgg cgaagactat gtttaccgtg ccggaacgat
     8041 tggtacagtc gccgacaaaa cagcatatgg ctatgtaaaa ggatacgaaa gggacaataa
     8101 tctgcagttt cgaagtgcag aagtcgacag attagcaaaa ggcgctactg gagtcaaacg
     8161 gacaaccggc cagcatccag gggggatcat cgttattccc gattatatgg atgtctatga
     8221 ttttacgccg atccaatatc cagcagacga tcaaaattcg gaatggaaaa cgactcattt
     8281 tgattttcac tcgattcacg ataatgtatt gaaattagat attctagggc atgatgaccc
     8341 aactgttatt cggatgcttc aagatttatc agggatcgat ccacaaacga tccctacgga
     8401 tgacccggaa gtgatgcgga tatttgccgg tcctgaagta cttggagtaa gtcaggaaca
     8461 aatttattcc aaaacaggga cattaggtat tccagaattc ggcactcgtt ttgttcgagg
     8521 gatgctagaa gaaacgcatc ctacaacttt tgcagaacta ctgcaaattt ccggactatc
     8581 tcatggtaca gacgtatggt taggaaatgc ggaagaattg attcgacgag gagatgcgac
     8641 actggcggaa gtaatcggct gtcgtgatga tattatggtt tatttgatcc atgctggatt
     8701 agatagcggg atggcattta aaatcatgga aactgttcgt aaaggacaat ggaacaagat
     8761 ccctgatgaa ttgcgagaaa cctatctatc ggcgatgaaa gaaaataatg tgcccgactg
     8821 gtatatcgat tcttgttcaa aaatcaaata tatgtttccg aaagcccatg ctgcagctta
     8881 cgtattgatg gctcttcgtg tcgcttattt caaggtttat ttccctattt tgtattactg
     8941 tgcatacttt tctgtacgtg cagacgactt tgatctagtc tccatgtgca aaggaaaaga
     9001 tgctgtgaaa caagcaatga aagaaatcac ggacaaagga ttagatgctt ccgtaaaaga
     9061 aaagaatcaa ctgacagtgc tggagttagc caatgaaatg ctggaacgag gattcaaatt
     9121 tggaatgatt gatttgtata aatcggatgc cgttaacttt gttattgaag gtgatacgtt
     9181 gatcgcacca tttagagctg tcccaagttt gggaaccaac gtggcaaaac aaatcgttga
     9241 agcaagaaaa gacggtccat ttttatccaa agaagatctt gccacccgcg gtaaagtttc
     9301 aaaaacattg atcgaatata tgaacgacaa tggcgtattg aaagatctac cagatgaaaa
     9361 tcaattatcg ttattcgata tgctataagc atctgttttc ctgtctgctt gtaattttaa
     9421 gcagagtatg gtatagttct tataggtaat gatactaact gtgagtgagc ggatttttcg
     9481 ctcactcttt ttaatggaat tacgcactta attttttaag gaggcgaaac ttttgagtag
     9541 cgtcgttgaa acagtcacag aaatggtgac accgatttta gatgaacaaa attttgaact
     9601 tgtcgaagtc gaatttgtaa aagaaggaaa aagctggttc ttacgagtat ttattgacaa
     9661 agaaggcggt atcgatatcg aagaatgcgc ctttgtcagt gagaaactga gtgaaaaact
     9721 tgatgcagca gatccagatc cgattcctca agcttatttc ctggaggtat cctccccggg
     9781 agcagagcgg ccattgaaaa aagaaagcga ctatgaaaag gcacttggtg attatgtcca
     9841 tgtctcctta taccaaccag tagatggcga aaaacaatat gaaggatttc ttcaatcatt
     9901 tgatgctgaa cagcttacat tgaaaatacg cataaaaaca cgagaaaaag aattgacttt
     9961 tgaccgaaaa aatattgcaa aagctcgctt agctatccaa ttttaatcac ggagaggaat
    10021 cagaaaaaat gagtaaagaa atgttaaatg cgttagacgc tttagaagct gaaaaaggga
    10081 tctcaaaaga aatcgtgatc gatgctttag aagcagcatt ggtttctgca tacaaacgtc
    10141 actatggcca agcacaaaac gtcgaagtgg aatttgatca gaaaaaagga aagatccatg
    10201 tctatgcggt aaaagaagta acggaagaag tgatggattc acagttggaa gtctcattga
    10261 aagatgcact tttaatcaat ccagcatatg agatcggtga tacgatccgt tttgaagtaa
    10321 caccaaaaga ttttgggcgg atcgctgcgc aaacggctaa acaagttatt ttacagcgtg
    10381 tacgtgaagc agaaagaacg attatttata acgaattcag tgcttatgaa aaagacatca
    10441 tgcaaggaat cgtcgaacgc caggataaac gttatattta tgtcaatctt ggtaaaattg
    10501 aggcagttct ttctaaacaa gatcaaatgc caaatgaatt ttatcaacca catgatcgaa
    10561 tcaaagttta tgtttcccga gtagaaaata cgtctaaagg tccgcaagta tttgttagcc
    10621 gcagccatcc agacctattg cgccgcttat ttgagcaaga agtaccagaa gtctatgatg
    10681 gaatcgttga aattgtcagc atcgcccgtg aagctggcga tcgttcaaaa gtggcagttc
    10741 gctcaaatga tccaaatatc gatgcagtcg gtacatgtgt cgggccaaag ggacaacgag
    10801 ttcaagcaat cgtcaatgaa ttaaaaggcg aaaacatgga tatcgtcgaa tggaatgaag
    10861 atccagctgt attcattgca aatgcattga atcctgcaca agtcatggat gtgatcttcg
    10921 atgagacaaa tccaaaggcc tgcacagttg tcgttccaga ctaccaatta tcgctagcaa
    10981 tcggtaaacg cggacaaaac gcacgtttag ctgctaaatt gactaaccat aaaatcgata
    11041 tcaaatcaga atctgacatg acggaatttt atgaaaatca agaacaacaa aaagaaacag
    11101 aagaactgca tgatgaagca atcgttcagt cagatttaac agacgatgaa tatgaaacaa
    11161 ttgcattcaa caatgaaacg gtcgaagaaa aaccagaagc ttaactttag taaggaggca
    11221 aagagatgaa acaaaggaaa attcctttac gcaaatccgt ggtttcaggt gaaatgaaac
    11281 ctaaaaaaga gatggtccga atcacccgtt caaaagaagg ggaagtatcg atcgatccaa
    11341 ctggaaaaat gcctggacga ggagcgtatg tctcacttga gccggaagaa gtacaacaag
    11401 cttgggataa aaaaattctc gatcgagtac tcgaaacaac attaacagat gagttttatc
    11461 aagaacttct tgactatgtc actcaccaaa aagcacgtaa agagttattt ggaaaatgaa
    11521 tacagttaat cggcaaaaag ccatgaatct catcggtcta gcgatgcgcg cgggaaaact
    11581 aatcacgggt gaagaactga ccattgctga aatccgcaaa caaaaagcaa aattggtgtt
    11641 tgtggcaacc gatgcaagcg agaatacaag aaaaaagata aaagataaga gttcatatta
    11701 tgaagttcct tgctttgagc tattttctga agcagaaatc acgcagatga tcggaaaacc
    11761 tcgcaaggta ttcggaataa tggatgccgg atttgcgaag aagaccaagg agctaattga
    11821 aggttaggaa ggtgattgca tgggcaacaa aagaatctat gaattagcaa aagaactcaa
    11881 aaaatctagt aaagacgtcg tggaaaaagc acaacaactt ggcatcgatg tgaaaaacca
    11941 tatgggtgcg attactagca atgatgagaa gaaattgcaa caagcgttca aaaacccaag
    12001 cacgaaacaa caagctgcac aacaagcaag cagaaaacca gccaatcaac agccgaacga
    12061 tcaacgtaaa aaagaaacaa cgaacaatca acaaaaaaat aaaaataacc gcagttatca
    12121 agatcgcggt caagggagcg gtcaagtgaa tcaaggaaaa aaaccaacaa caaaccaaaa
    12181 taatacggga aataccagca gccaaaatcg tcaaggaacg agccaaggcg gcaatcaaaa
    12241 ccgtactaac aataacaaca aaccaaacaa taacaatcgc ggcaaattta ataataataa
    12301 ccgtaatcgt tataataaaa aaggtaaaaa aggcaaacag caacaatcaa ctaaaccagc
    12361 tgtaccacca cgcaaattcc gtgaattgcc agatgtatta gagtatactg aaggtatgaa
    12421 cgtagcagat attgcgaaaa aaattcatcg tgagccagca gaaatcatta aaaaattatt
    12481 tatgcttggt gtcatggtca atcaaaacca agcactggat aaagatacga ttgaactgtt
    12541 agcgacggac tatggcatgg aaccacaaga aaaagtccaa gttgacattg ctgatatcga
    12601 taaattcttc gaggcagaag aagtcgatcc agataaatta gtctcacgtc cgccagtcgt
    12661 aacgattatg ggacacgtag accatgggaa aacaacttta ttggatacat tacgccattc
    12721 acgtgtaaca agcggcgaag ccggcggaat cacacagcat atcggtgcct accagatcga
    12781 tattgatggt aaaccaatca ctttcttgga tacaccagga catgcggcct ttacaagtat
    12841 gcgtgcacgt ggagcaagta tcacagatat cacgatctta gttgttgctg cagatgatgg
    12901 cgtcatgcca caaacagttg aagcaatcaa ccatgccaaa gctgcaggcg ttccaatcat
    12961 cgtcgctgta aataaaattg ataaaccagg tgcaaaccct caacatgtta tgcaagaatt
    13021 aagtgagtat gagttaattc ctgaagcatg gggtggagaa acgatctttg ttgagatctc
    13081 agcgaaattc ggccaaaaca tcgaagaatt gctggaaatg atcctgttag tcgcagaagt
    13141 agaagattta aaagcagatc caacacaacg cgcaatcgga acagtgatcg aagcacgtct
    13201 tgataaaggt aaaggtcctg tgtcaacctt acttgtccaa gaaggaacac ttcatgttgg
    13261 tgacccaatc gttgtcggta atacttacgg acgtgtccgt gtaatgacaa acgatcttgg
    13321 ccgtcgcgat aaagaagcag gacctgcaac gccagtagaa atcactggct tgaatgatgt
    13381 acctcaagca ggtgaccgtt tcgtagtctt cgaagacgaa aagacagcac gtgcagcggg
    13441 tgaagaacgc gcgaaacgtg cattattaga aaaccgtgct gccacaagcc gtgtgacttt
    13501 ggataactta tttgaaagcc tgaaagaagg cgaattgaaa gaagttaacg taatcatcaa
    13561 agcagatgta caaggttcag cagaagcact ggctgcatca ttgaagaaga ttgatgtgga
    13621 aggtgtccgt gtaaaaatcg tccattcagc tgtcggagca atcaatgaaa gtgatgtaac
    13681 cttagcagca gccagcaacg ctattatcat cggtttcaac gttcgtccta caccgcaggc
    13741 aaaagtgcaa gctgatactg aagaagtcga tattcgtctt caccgtatca tctataaagc
    13801 catcgaagaa atcgaaactg cgatgaaagg gatgctagac cctgaatttg aagaaaaaat
    13861 caccggtcaa atgatcgttc gtgaaacctt caaagtttct aaagttggta cgattgcagg
    13921 tgcctatgta acagaaggat atattcgtag agatagcggt gtccgtgtaa tccgtgacgg
    13981 aatcgtaatc tatgaaggcc aacttgcaag tctgaaacga ttcaaagatg acgtgaaaga
    14041 agtcaaaatg ggttatgaat gtggtgcaat gattgaaaaa ttcaatgaca tcaaagtaga
    14101 tgacgtaatt gaaggattta tcatggaaga agtcaaaaat gactaaaaac tgataaaagg
    14161 aggccaatca ttatggctaa ctaccgtgac cgccgagtcg gtcaagaaat cttaaaagaa
    14221 gtcaatgata ttttgcgcaa aaaggtccgt gaccctcgtg tggagaacgt aacgatcaca
    14281 gatgtgaaag ttacggggga cttacagcaa gcaacgatct attacagcat tttatctgac
    14341 ttagcatcag ataagaaaac agcacaagat ggattgaata aagcatcagg attgattcgt
    14401 cgagagttag ggcacaatct aagtatttat aagacacctg aattgttctt tgaacttgat
    14461 gaatcagttg tctatggcaa ccatatcgat gaattgcttc gcgacttgaa caaagactaa
    14521 tcaaaaactc ccgcaaatcc tgtgaaatca ggctctttgt caataaggac tgatgagttg
    14581 tgcaaaatca aatctgagtc agaatgaacc acattctggc tcag
//
LOCUS       DAPBAF010000060        14333 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.060, whole genome shotgun sequence.
ACCESSION   DAPBAF010000060 DAPBAF010000000
VERSION     DAPBAF010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14333)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14333)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14333
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.060"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(26..328)
                     /locus_tag="RD451_002412"
     CDS             complement(26..328)
                     /locus_tag="RD451_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDT7567627.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
     gene            complement(353..2446)
                     /locus_tag="RD451_002413"
     CDS             complement(353..2446)
                     /locus_tag="RD451_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HDT7567628.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLVEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNAPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            complement(2935..3699)
                     /locus_tag="RD451_002414"
     CDS             complement(2935..3699)
                     /locus_tag="RD451_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HDT7567629.1"
                     /translation="MKKINYLAIILLVGLCLFALPTQGFAVAGGHGGGTSSGRSSGRG
                     SFGGRSYGGSYFGSRSYGRDSYGYYGPGTGPSSYEQTGFLALAVLSVGGVSAFSIVKN
                     KRQKKRLKAEILSRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFA
                     EHQKVLQKNKADGVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLI
                     SGSKTQRQYFSQIWYFDFSEKEKRWQADFIQPIMLD"
     gene            complement(3810..4679)
                     /gene="mdcB"
                     /locus_tag="RD451_002415"
     CDS             complement(3810..4679)
                     /gene="mdcB"
                     /locus_tag="RD451_002415"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
                     /protein_id="HDT7567630.1"
                     /translation="MINDERKKAVTQQLAALVEEALIAEVTLSPKPGLVDALDAGAHS
                     DMDYALFLKSAKTLTPFFEEMAQIAWHHAIDQELRERIAEIGRKAEKAMLIATNGINT
                     HKGAIWAMGLLISVIAQKISMEQPFSLSKILDDVSKLAAFPDTKYRHKKTTHGHRVKQ
                     KYGVNGAYEEAILGYPHIRLAIQAAKELDNDSYVQKQMHMLLVLMSSLDDTCVLHRSD
                     QKTLVEMQKLAHAASQSALPNRPFTALLHFCQENQISPGGSADLLSASLFMLKIEELW
                     TADTYICPMLLND"
     gene            complement(4704..5780)
                     /locus_tag="RD451_002416"
     CDS             complement(4704..5780)
                     /locus_tag="RD451_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HDT7567631.1"
                     /translation="MFENKKIKINVSDFQKVSAVTAVMMQTILSFALANSHSATNTAF
                     LGTFYVIVKYTAPMFIFAIVYNMVKTSQHLSYWEFLKEKFFELVVPYLLWTTAYLWLF
                     PAVQQQTPYTDTASFLLKYVTGDGAPHLWYTVMMLQIQLFMPFFVWLGYKVFANKKYV
                     WPVLIGSTILYVAWYLFYQTQVLTGPYHDSWYLLDRFVASFMIYGVAAFVYHEKVYQY
                     LDRVRYLFLPVALVIAFFSVRSLLAHPGDLSFANAPYLNTIQSLYSLVIIFAVFIGAS
                     KMIVNDSPKLPLFKWLSVYAYRTYLANVFVFQVLLLLFKDSWLQLPSGVMILVAYLMT
                     ASCAFALSWLLHIIWVAIKKGFSK"
     gene            complement(5804..6397)
                     /locus_tag="RD451_002417"
     CDS             complement(5804..6397)
                     /locus_tag="RD451_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase holo-ACP synthase"
                     /protein_id="HDT7567632.1"
                     /translation="MIQAHDIVLFDKHEIEGFTLPEWVVLTEKMFGTVRRASTDHAEI
                     LPIGLRGPARNQRWSTEISKHAVKQVIHPWDIIEQESYRQEKIMDYPVYQQFHAARNI
                     LSGCKWGIGGSLGFELSTGIPAVKETSDFDLLLYANSPIELPIQVIQSHPAFFEQFDT
                     QVVTRQGGFSLKEYLREPEKKILLKTVEGPKLTKELW"
     gene            complement(6401..8077)
                     /gene="mdcD"
                     /locus_tag="RD451_002418"
     CDS             complement(6401..8077)
                     /gene="mdcD"
                     /locus_tag="RD451_002418"
                     /EC_number="4.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-independent malonate decarboxylase
                     subunit beta"
                     /protein_id="HDT7567633.1"
                     /translation="MKNSFVELNARERVNALLDNGRELIDPFDQIIAPSLPAQGIVPE
                     SDDGIVVSRGTINGKQAVVIAMEGKFQGGGIGEVSGAKIVAALEHVLEENKKGNEIFP
                     VIVLDTGGVRLQEANYGLLSISEIGNVIIALKQYVPVIGLIPGRVGSFGGMSITSALM
                     SYLIATKKARVGLNGPEVIEQEAGVREFDSSDKDLIWNTLGSRQRVESKIIDELVTDS
                     VEAIKAAVIAAMDERKDTHRSESSAFYLSLLDSLDLSKPMAIDDYNEAIANHQAKSID
                     LPEVAEGNEPAAASVGYDWFAALTGMKNPTSSISTVYYGKSSKFIEEAIVTSIVPDPK
                     NPMYRVRNGEVGLVEGFRMGQILDHVYEEDKDKKVKRPIIVVIDVPSQAYGYNEELIG
                     IHVALANSAAAYAKLRQAGHPVIGLIAGNAISGAFLAHGLQSSRLIALNNKEITVQAM
                     SKESAARVTKRSVAEIEAAAEKVPAIAYDINNYTKLGAIYHFLEDITDQAASEQNVSK
                     VIEAINEAIQDVRNTNDTMLTNRYTNETAKTFGRVETNKVRAKMDEEWDA"
     gene            complement(8067..8366)
                     /locus_tag="RD451_002419"
     CDS             complement(8067..8366)
                     /locus_tag="RD451_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit delta"
                     /protein_id="HDT7567634.1"
                     /translation="MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKTESTVKI
                     CTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK"
     gene            complement(8468..10114)
                     /gene="mdcA"
                     /locus_tag="RD451_002420"
     CDS             complement(8468..10114)
                     /gene="mdcA"
                     /locus_tag="RD451_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit alpha"
                     /protein_id="HDT7567635.1"
                     /translation="MEKPNRNWASKREKKAQRLEKISNLLNGKYVETEKIVEVMEKLI
                     APGDKVVLEGDNQKQASFLSESLEKVDAEKVNDLHLIMSSISRPEHLNIFEKGIASKI
                     DFSYAGAQSLRVAQMIEDGTMKLGDIHTYLELYGRLFIDLIPNVVLVAADKADKDGNL
                     YTGFNTEETPTIIEAAAFKDGIVIVQVNEVVDSLPRVDIPGDWVDVVVKADKPYQLEA
                     LFTRDPQNITELQILMAMMAIKGIYAEHGVQSLNHGIGFNTAAIELLLPTYGESLGLK
                     GKIAKNWVLNPHPTMIPAIESGWVESIHSFGGEVGMEKYIAARPDVFFVGKDGTMRSN
                     RTLSQAAGQYAIDMFIGSTLQLDYEGNSSTVTKGRLSGFGGAPNMGHNPGGRRHSTPA
                     WQSLRDNDDPLGKGQKLVVQMVETYGSNKKPVFVEELDALAVQKQAGLANAPVMIYSE
                     DTTHIVTEEGIAYLYKAKTKEERQAAIAAIGGVTPLGMTSTKESLDSLRAAGIVKLPE
                     DLGIKRSEAKRSLLAAQTIDDLIEWSDGLYEPPMKFRTWS"
     gene            complement(10121..11032)
                     /locus_tag="RD451_002421"
     CDS             complement(10121..11032)
                     /locus_tag="RD451_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HDT7567636.1"
                     /translation="MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENY
                     QDTVFIQLALLTKAVFYLDEMEKNGIQPDIAAGHSIGAFCAAVACRSLRFENAAELVY
                     HRAVLMKEAYPSGYAMGVVVGVTRSEAEEIVAKTFDPDHPVYLSNENCPMQHTLSGSI
                     EGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLSDARCLYIKN
                     TDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKF
                     GVDKGIRTINLDQHGIDDATFLYQKWR"
     gene            11152..12009
                     /locus_tag="RD451_002422"
     CDS             11152..12009
                     /locus_tag="RD451_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDT7567637.1"
                     /translation="MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELG
                     VPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEVASV
                     SIPNLVRIFMEKHPDIQLTIMQHHLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAI
                     PKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSIELTISSTTDDPATL
                     RSIVKQGLAVSFFPKVSWSYDKNDPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAK
                     TMREFYLGK"
     gene            complement(12196..12558)
                     /locus_tag="RD451_002423"
     CDS             complement(12196..12558)
                     /locus_tag="RD451_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HDT7567638.1"
                     /translation="MLTKKELIDHINETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVL
                     MSVPEEKIYDDASDHRIINILDLKVDPELGGILRGKEGYFPAYHMNKEHWISIDLRKI
                     EKLDELADLIDGSFKSTQ"
     gene            12904..>14333
                     /locus_tag="RD451_002424"
     CDS             12904..>14333
                     /locus_tag="RD451_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7567639.1"
                     /translation="MYSLMKKIITEKDIRRHVSLVEQLLNHTKITVNELAEIIGTTER
                     TIFSDLQSIRSQLPEGWDIISDQAGISLQNQQNLLTNDLWEIFFKQSVSVELLKNLLF
                     TKKVAVPDFLADHGLSYGTLKRHVTKINQRLASYDLQIDLTKYTACILGKERAIRTFY
                     HRLLIPFTHNNYFFEDYSIHESHYFQFLRNLSQTELAVETEEIFGTCWFFINTIRIKA
                     NCRLDSSIHTNSTLSSLYDSALKKLYLTEGIYLKDTELSFASFCFLESWNYNNNYGQE
                     TARCLHHSPFLEVLETFVEELASELSLDQLKKTSLTDNLALLILKYHESPILIEALDR
                     QYHRFLETYDQQYAHLYQQKENLLNDLKKEIEINEPNYFLQLLSLLIQQTIFSIKPNL
                     FNVYFIFQGEPSWKAFLQQELKDYLGKRVCFLPIELTDLSTISFEKTDILISNFPLDS
                     LDIPIVYISSIPTKNELNRLTELTFKT"
BASE COUNT         4103 a         3027 c         2468 g         4735 t
ORIGIN      
        1 tttttaccct cttttctttt tgtatttaga taactccctt atcttgcaga actggggtga
       61 ttttttcttc aatttcattt tttgaaacaa tatttttcaa atagatcatc gccgttttag
      121 gatcaactgc gaacttttcg aactgcgaac gaaaattttc tgctgtgatg atcacatctg
      181 gtttcatgga aactgcggaa gaaatatcac aatggtccag tttggcttct actcctaatt
      241 tgttcaaaac atcctcagca gacatctgtg ctgcaaaact acttcctaaa cctgcaccgc
      301 atacgaataa aatgttcaat ttgttcatct ttgttctccc ccgtatcatt tattatttct
      361 caactactga aaaaagcagt tgtttgaaat cttcgatatt tgtgcattca atcaatcgat
      421 ccaacttctc ttcgttgttg atcaattcaa ttagttcttt catgatgttc agatgcgagt
      481 aggagtctac tgctgccaaa caaaaaataa tctttactgg atccatttca ggattaccga
      541 aatcgattgg ttgctcaatc gtagctacgc tgactcctaa tttattgacc ccatcttctg
      601 gtcgggcatg ggctagtgcc atgtgtttgc caatcacgat atacggtccg taatcattca
      661 ctgcacgaat catcgcttcg acatagcgct cttcgacaat gttttcttta accaatggtc
      721 tagcagctag ttcaatcgat tcctcccaag tagtggcttt ttctttgatc atgatattgc
      781 tgtccgtcaa aatatctttt aacataggct ggatctccct tttgttgatt tctaaattgt
      841 ttgtttcgaa taatttttct aacttgccat agatgattcg atctactcgg ccaccacttt
      901 ctttcatgac atctattatt tgagtgaata actccgtcga ttcatgactg ttaggctcta
      961 accgctgtag ttcttcattt cttttcaaaa agtcttctat aaccaagata ttcgtctcag
     1021 ttaaaatcgg atcgacaact aaaagcggct tatttcgata attcaattga aaggtgctga
     1081 aaaccagatt gacatccaat ttatctacta attcgatttc ttttgaactt aaaactgcag
     1141 taatctcgat ctgaggaaac ttttctttca gattctctgc taacagattt ccagtagcca
     1201 tcccatggtt acagacaacg actgatttat aaacataatt caagtctcgc ttgattacac
     1261 tggcgatcgt cgaaaagtgg atgacaagaa aagctatctc gtcctccagt atcttgccac
     1321 caattacttc ttcgatcgta ggaacaaaat gagtgactgc gcggtagatt gggaaataat
     1381 ttgttcggat gttttctttc aatggattca tgacttggat atgattcttg attcttacaa
     1441 tcagtgcagc catgtgctta tagagatttt cgaataaagc ttcttccttt agatggaaag
     1501 gtacgtgtgt ctcgttctct acaaattgga tcaattggat cgttagtaat tgagcttgta
     1561 cccactcgat tgaattggag atatctctag cattgaacgt ctcaatagtg aaacgaagat
     1621 aatttctttc tacttgcggg gcattgtcca attgaaattc ctcgatcatg tggtcaataa
     1681 atgcagaaaa gctactgtct tttatttctg tatttttcca attaatggca gagataaatt
     1741 catgtttcct gattcgctgg atccagatca atgtaaaaag caggatttgt tttttataaa
     1801 tatcatcttc ttgtttcaac aacttattgg aatagatctc ctgtattttt ttgatttcca
     1861 ccaaaggaaa ataatggaga aagatttttt gagccggtgt taattgtgca tcttgattca
     1921 taaagaagtc ggtcattccc agattctgat tgataaaatc atagatcatc gtacggatag
     1981 atcgttctga acctttataa accagtcctt gctttccata actgacgatc tctatcccat
     2041 aactgaccag tgttgctcgt aaccgtctca tatcttcatc taatgtactt ttagagattt
     2101 gaaattcttc ttcttttttg tttagatgga tcgggattcg gctgtaagca acggctaaaa
     2161 ctagatcaaa aatacgttcg cgccgattca aaaagccgtc tttcacatct tttatttcag
     2221 tttctaatcg agcttgcttt tccttttcca gcttcaacaa aaaacctttg ttgcgaattg
     2281 tacggatctc cggaagcttt ttactgctca accagatatt cgcttcaaga acttcctgac
     2341 ggatcgtccg ctgactgaca ttgaactcac ttgctagatg ttttgctttt actggatatt
     2401 gggctgtcat gattctgtga agtatttcaa ttgttcttgt tttcatagaa atgatctcct
     2461 tctgatttca agtatatggt tccgcttaca taataaaaag tagatatttc tgccacttga
     2521 agtggaaaga aagtaagcaa agcaaacaaa aaataagcca tatgcttttt catctcctca
     2581 acgaaaaaga catacgccta ttattacaaa aattttgccc atctatacaa aaaagaggtt
     2641 gtgaaaaagc tgtcctgcat caagtaataa gaacaactaa actaaaatag tgcttcctat
     2701 ttttcgtttg gttgttctta ttatcgcaga tgcaagcttt taaacaccat ttagtggaga
     2761 ggttgtgaca gagatgttca gccttgagcg ataagaagcg attttgaaaa atcgcttccc
     2821 atattttaca aaatcgtgcc ttattgccga taggctatct ctggcacacc gtttattcag
     2881 aaaaaggagc tgcgacaagg cttttgtcac aactccgttc ataaatattt cctgtcaatc
     2941 cagcataatc ggctgaataa aatcggcttg ccatcttttt tctttctcag aaaaatcaaa
     3001 ataccatatc tgagaaaaat actgtcgttg tgtcttactt cctgagatca atcgcccatc
     3061 ttttcgatcg actgaataat cacagcatct gaaatcaatt cggatggcaa aactattttc
     3121 gtggatctgt cgataatttc ctacttcctg aatagttatt tttttagtat gatttcttac
     3181 accgtctgct ttgttttttt gcagaacttt ctgatgttcg gcaaacagct tgtctgtata
     3241 acagcttctg gctttttcag gagtttcttc ttcccaagcg gattggatct tcatgaatat
     3301 cttttggatt tccagaaact gtgctttctt ttctttagcc gttcctgaca tgcgggacaa
     3361 tatctccgct ttcagccttt tcttttgtct tttattcttg acgatagaaa aagcagaaac
     3421 ccctcctact gacaaaacag ctaatgcaag aaatcccgtt tgctcataac tagaaggacc
     3481 tgtacctgga ccataatacc cataagaatc tctgccgtaa gaacgactgc caaaataact
     3541 gcccccatat gaacgaccac caaatgaacc tctgcccgaa cttcgaccgc tagatgtacc
     3601 tccaccatga ccacccgcga cagcgaatcc ttgggtcggc agagcaaaca aacataggcc
     3661 cactaacaaa atgattgcta aataattgat ttttttcatt gtcttcctcg ttatctttta
     3721 ttacaaaaaa ctatttttat gatagccttg ctaaaaggaa gagtcaataa ccagatgcat
     3781 aaactgtttt tttagcaatt ttgtcttatt tagtcattga gtaacatcgg acaaatgtat
     3841 gtgtcggcag tccataattc ctctatcttc agcatgaaca agcttgcaga caagagatct
     3901 gcgcttcctc caggagagat ttggttttcc tgacaaaagt gcaacagtgc tgtaaatgga
     3961 cgatttggta aagcactttg actagcagca tgagcaagtt tttgcatttc cactaacgtt
     4021 ttctgatcac tgcgatgcaa tacgcatgtg tcatctagcg aactcatcaa aactaacaac
     4081 atatgcattt gtttctgtac atatgaatca ttatctagct ccttagctgc ttgaattgca
     4141 agcctgatat gcggataccc taatatcgct tcttcatatg caccatttac gccatatttt
     4201 tgcttcaccc tatgaccatg agtggttttt ttatgacgat attttgtatc aggaaaagca
     4261 gcaagcttgc tgacatcatc aagtattttc gataaagaaa aaggctgttc catactgatt
     4321 ttttgtgcaa tgacactgat caatagcccc attgcccaaa tcgctccttt atgggtattg
     4381 atgccatttg tagcaatcag cattgccttt tccgcttttc gcccaatctc agcaattctt
     4441 tctcttaact cctgatcaat agcatgatgc catgctattt gagccatttc ttcaaaaaaa
     4501 ggagttagcg tcttagcaga cttaagaaat aaagcatagt ccatatcgga atgtgcaccc
     4561 gcatccagtg catccactaa tccaggtttt ggacttaatg ttacttctgc gatcaatgct
     4621 tcctctacca acgcagcgag ttgctgagtc actgcttttt ttcgttcgtc atttatcatg
     4681 acactcactc cttcttccta ctattacttg ctgaaacctt ttttgatagc tacccaaatg
     4741 atatgaagta accagcttaa agcaaatgca caacttgccg tcattagata agctacaaga
     4801 atcatgactc ctgaaggtaa ctgcagccaa ctatctttaa acaataataa cagtacttgg
     4861 aaaacaaata cattggctaa atacgtacga taagcataaa cagacaacca tttgaacaat
     4921 ggcaattttg gcgaatcgtt tacaatcatt ttggaagcgc ctatgaagac agcaaagatg
     4981 atgactaaac tgtataaact ttggatcgta ttcaagtaag gtgcattcgc aaagctcaag
     5041 tctcctggat gtgcgagcaa tgaacggaca gaaaagaacg cgataactaa ggcaacaggt
     5101 aagaaaagat aacgtactct gtccaaatat tgatagactt tttcgtgata aacaaatgcg
     5161 gctaccccat aaatcatgaa actagcaaca aaccgatcta ataagtacca gctgtcatga
     5221 taaggcccag tcaatacttg tgtttgatag aacagatacc atgcgacata taaaatcgtt
     5281 gaaccaatca atactggcca tacatatttt ttattagcaa atactttgta accgagccaa
     5341 acaaaaaacg gcatgaacaa ttggatctgc agcatcataa cggtatacca taaatgaggc
     5401 gctccatcac ctgtgacata tttcagtaaa aagcttgcag tatccgtata cggagtttgt
     5461 tgttggactg ctggaaatag ccaaagataa gccgtcgtcc atagaagata cggaacgact
     5521 agttcaaaaa acttttcttt caaaaattcc caataagaca aatgctgact tgtttttacc
     5581 atattataaa caattgcaaa aataaacatt ggtgctgtgt atttaacgat gacgtaaaag
     5641 gtaccaagaa aagctgtatt tgttgcgctg tggctgtttg ccaaagcaaa gctcaatatc
     5701 gtttgcatca taacagccgt tacagctgat actttctgga agtcacttac gttgattttg
     5761 atttttttgt tttcaaacat ctctttctct ctctttttct ttattaccaa agttctttgg
     5821 ttaatttagg tccttcgact gttttcaata gaattttttt ctctggctct ctcaaatact
     5881 cttttagtga aaaaccgcct tgccgagtca ctacttgggt atcgaattgc tcaaaaaaag
     5941 caggatgcga ttgaattacc tgaattggca attcaatcgg tgaatttgcg tacagcagca
     6001 aatcaaaatc actggtttct tttactgccg gaatcccagt cgataattca aatcctaagc
     6061 tgccgccgat tccccattta catcctgata atatgtttct agcagcatga aattgctgat
     6121 aaacaggata atccatgatt ttctcttgtc tatacgattc ttgttcgatg atgtcccacg
     6181 gatgaatgac ttgtttgacg gcatgttttg agatttctgt tgaccatctc tgattgcggg
     6241 caggtccacg taaaccaatc ggtagtattt ctgcgtgatc cgtcgacgca cgacgaactg
     6301 ttccgaacat cttttcagtt agaacgaccc attcaggcaa ggtgaaccct tctatttcat
     6361 gtttatcaaa aaggacaata tcatgtgctt gaatcatttt ttatgcatcc cattcttcgt
     6421 ccattttggc acggacttta tttgtttcga cacgtccgaa tgttttggct gtttcgtttg
     6481 tgtatcgatt tgtcagcatc gtgtcatttg tattgcggac atcttgaatg gcttcattga
     6541 ttgcttcgat gactttgctg acattttgtt ctgaagcagc ttggtcggtg atatcttcta
     6601 ggaaatgata gatcgctcct agttttgtat aattattgat atcgtaagcg atagctggaa
     6661 ctttttcagc agctgcttcg atttcagcaa ccgaacgttt tgtcacacgt gcagcacttt
     6721 ctttagacat cgcttggacg gtaatttctt tattgtttaa agcaatcaag cggcttgatt
     6781 gtaatccatg tgctaaaaat gcacctgaaa tagcatttcc tgcaatcaat ccaataactg
     6841 gatgtccagc ttgacggagt tttgcataag cagcagcact attagccaaa gccacatgga
     6901 taccgatcaa ttcttcgtta tagccgtatg cttggcttgg tacatcgatc acaacgatga
     6961 ttggccgttt cacttttttg tctttatctt cttcgtaaac gtgatccaaa atttgtccca
     7021 tgcggaaacc ttcaactaaa ccaacttcac cgtttcgtac acggtacatc gggtttttag
     7081 gatcaggtac gattgatgtc acgatggctt cttctatgaa tttacttgat ttaccataat
     7141 acacagtact aatagaagaa gttggatttt tcatgccagt tagtgccgca aaccaatcgt
     7201 aaccaacact tgctgcagct ggttcatttc cttctgctac ttctggtaag tcaattgatt
     7261 ttgcttgatg gttagcaatt gcttcattgt aatcgtcaat ggccattggt tttgaaagat
     7321 ctaaagaatc aagtaatgat aaataaaatg ctgagctttc actgcgatgc gtgtcttttc
     7381 gttcgtccat tgctgcgatg acagcagctt tgattgcttc tacactatca gtcactaatt
     7441 catcaatgat ttttgattct acccgttgac gagatcctaa tgtattccaa atcaagtctt
     7501 tgtcactaga atcaaattct cgaacgcctg cttcttgttc aataacttct ggtccattca
     7561 aaccgactct cgcttttttt gttgcgatta aataactcat taatgctgaa gtaatcgaca
     7621 taccgccaaa tgatcctaca cgtcctggaa tcaaaccgat gactggtaca tattgtttta
     7681 gagcaatgat tacatttccg atttctgaaa tagataacag tccgtagttt gcttcttgca
     7741 aacgaacacc acctgtatct agtacaatga ctggaaagat ctcatttcct tttttatttt
     7801 cttctaacac atgttcaagt gcagcaacga tttttgcacc ggaaacttca ccgataccgc
     7861 caccttggaa ttttccttcc atagcgatta ctactgcttg tttgccattg atcgtgccac
     7921 ggctgacaac gatcccgtca tcactttcag ggacgattcc ttgtgctggt aaacttggcg
     7981 cgatgatttg atcgaatgga tcaatcaatt cacgtccatt gtcaagtaga gcgttcactc
     8041 gttctctggc gtttaattct acaaaactat ttttcatctg aaagttcctc cattgcttgc
     8101 gtcaatcgta ggtacacaac tcctggtgta gcaccgaagt cattgatcac gatatctgct
     8161 gaaattggat aacgatcaaa aaatctcgtt aatacattgt tccatacttc gccgaagcca
     8221 tcgcttcctg tacaaatttt tacagtagat tctgtttttt ctgttggaaa catcaagatt
     8281 tccaaatctc ctgaaccgac cactcctaca tggattttct tattgatcgg ctgtttcgtt
     8341 ggatatttat aagctaattg ttccatggat ctctcccctt tttgtaaaac agagcataca
     8401 cgttctgctt attcgtcttt cttcttccat ctgggtaaat ggcgacaaaa ggtttttctc
     8461 gccaatttta tgaccaagtt ctgaatttca ttggtggttc atacaggcca tctgaccatt
     8521 cgatcaaatc atcgatggtt tgtgcagcta ataatgaacg tttcgcttca ctacgtttga
     8581 tgcctagatc ttctggtaat ttcacgatgc cggctgcacg caagctatct agtgattctt
     8641 tcgtgctagt cattccaaga ggtgtaacac cgccaattgc tgcaattgct gcttgtcgtt
     8701 cttcttttgt ttttgctttg tacaaataag caattccttc ttctgtcacg atatgtgtag
     8761 tatcttcgct ataaatcatc actggtgcat tggctaagcc tgcttgtttt tgaacagcta
     8821 gtgcatctaa ttcttcgaca aagactggtt ttttatttga accatatgtt tcaaccattt
     8881 gaacaactaa tttttggcct ttccctaatg gatcatcatt gtcgcgaagt gattgccatg
     8941 ctggtgtaga atgacgacga ccgccaggat tatgtcccat gttaggcgca ccgccaaaac
     9001 cagataaacg tccttttgtt acggtagaag agtttccttc gtaatctaat tgcaaggttg
     9061 aaccgataaa catatcgatg gcatattgtc ctgcagcttg tgataatgtt cggttactgc
     9121 gcatcgtgcc gtctttaccg acaaaaaaga catctgggcg agcagcaata tatttttcca
     9181 taccaacttc gccaccaaaa ctatggatgc tttcaaccca acctgattcg atggctggaa
     9241 tcatcgttgg atgtgggttc aatacccagt tcttcgcgat tttccctttt aaccctagtg
     9301 attcaccata agttggcagt aacaattcga tagctgctgt attgaatcca ataccgtgat
     9361 tcaaagattg tacgccgtgt tctgcgtaga ttcctttgat tgccatcatt gccattagaa
     9421 tttgcaattc tgtgatgttt tgaggatctc gtgtgaataa agcttctaat tgataaggtt
     9481 tatctgcttt cacgacaacg tctacccagt caccagggat atctacacgt ggtaaagaat
     9541 cgacaacttc gttaacttga acgatcacga taccatcttt gaaagctgca gcttcgatga
     9601 ttgttggtgt ttcttccgta ttgaaacctg tgtacaagtt gccgtcttta tctgctttat
     9661 ctgcagctac taaaacaaca tttggaatca aatcgatgaa taagcgtcca taaagttcca
     9721 aataagtatg gatatcacct aatttcattg tgccgtcttc aatcatttgg gcgacacgca
     9781 agctttgtgc accagcataa gagaaatcga tcttgcttgc gattcctttt tcaaaaatat
     9841 tcaaatgttc tggtcgtgag atactagaca tgatcaaatg cagatcattc actttttctg
     9901 catctacttt ttcaagactt tctgaaagaa aacttgcttg tttttgattg tcgccttcta
     9961 atacaacttt gtcgccggga gcaatcagtt tttccattac ttctacgatt ttttcagttt
    10021 ctacatactt gccattgagc aagttgctga ttttttccaa tcgctgcgct tttttttcgc
    10081 gtttagaagc ccagttgcgg tttggttttt ccataattag tcatctccat ttttgatata
    10141 gaaacgtggc gtcatcaata ccatgttggt ctagattgat cgtacggatc cctttatcta
    10201 caccaaattt tgtatgaatc agctttgtca aagtattgcc ggggggaaat tcaatcgtca
    10261 gatccattcc taattctttt gccaagtcca tcatttggtt ccactgcaca gggaaagcta
    10321 ggttttccaa caaatcttta cgaatctctt ctgcgtcctg agtggctctt ccatccgtat
    10381 tttttatata caaacatcta gcatcagata gatggacaga ctgcatatac ggcttgaatt
    10441 tcttgaccgt atcattcatc aagagacagt gagatggcac agggactttc agcagcttcg
    10501 ctgtttgcgc ttggtgccgt ttggcttctg ccaacgtaac ggataaacct tcgatactcc
    10561 cagataacgt atgttgcatc ggacaatttt catttgacag ataaactgga tggtcaggat
    10621 caaatgtttt tgctacaatt tcctcagctt cgcttctcgt cacacctact actacgccca
    10681 ttgcataacc gcttggataa gcttctttca ttaagactgc gcggtgatag actagttccg
    10741 ctgcattctc aaatctcaaa gatcgacaag caacagctgc acaaaaagca ccaatcgaat
    10801 gtcctgctgc aatatcaggc tgaataccgt ttttttccat ttcatctaaa taaaatactg
    10861 cttttgtcag taatgctagc tggataaaaa ccgtatcttg atagttttct tctttatcaa
    10921 ctaaccgata ccccgtcaca ttttctaaac gttccatgta catttcaggg atatccgcta
    10981 acatccctaa cttctgactg ccttgtccag gaaataagaa acctgtactc atgagcctcg
    11041 cctcctcagc acttactttt tccactgcta tcttagtcaa tttctgctat aataaaaaat
    11101 gccaaaaaaa gaaaaaacca taacaaaaag gtatggatgg gatggataat tatgaaattg
    11161 cttcatctgc agtattttaa aaaagtattc gaaacaaaaa atgttaccca agcagccaaa
    11221 gaattattta tttctcaacc tgccttgagc cgtgcgatca aacatttgga aaacgaatta
    11281 ggtgtccctt tgttttacca tagcggcaga aacattgaga cgaccgttta tgcagaagaa
    11341 ttttatccat atgcagtcaa gacattagac acattagaag aaggaatcaa attattgtct
    11401 tcggtcaatg agaagatcgt tacttccgtc atattgtatt tagaggtagc ctctgtttct
    11461 attccgaact tggtccgaat ttttatggaa aagcatcctg atatccaatt aacgatcatg
    11521 caacatcatt taccagatga tattaccgat cctgtactgt acatcacttc ggagatgaag
    11581 cctggcatga ccaatattcc tatcatgaaa gaacctgttt atgtcgccat tcctaagaaa
    11641 catcctcttg ctaaaaaaga acatctgcaa ttagaagata tccaacgcac ccccatcttg
    11701 atgctgtcaa agagcaacgc cttccgtcat acactggatg cagcacttga agcgaaaagt
    11761 atcgaattga cgatcagttc gacgacagat gatcctgcga cattacgttc tattgtcaag
    11821 caaggattag ctgttagctt tttcccaaaa gtttcttggt cttacgataa aaatgatcct
    11881 ttcgtcttgc gggaaatcaa agatttgccc ttgacacgaa caatttattt atcttctagc
    11941 ttcacagaag atcatccttt gatcaaaatg attgcaaaaa cgatgcggga attttattta
    12001 ggaaaataaa aaaaaaagag ctgggacaaa attcttgtcg cagctctttt ttcgaacaaa
    12061 cggtgttcca gaagtaattt cttagaaaat aagccgaaat ttcccaaaaa tttgagaagc
    12121 aattttcgta aattccttct tatttcttga agctaaacat ttctgtcaca acctcttctc
    12181 tattgtccta gacattcatt gcgttgattt aaaacttcca tcaatcaaat ctgctagttc
    12241 atctagcttt tctattttac gtagatcaat agagatccaa tgttctttat tcatgtgata
    12301 ggctggaaaa tacccctctt ttcctcgcaa aattccgcca agttcaggat cgaccttcaa
    12361 atcaagaata ttgatgatcc tatggtcact tgcatcatca tagatttttt cttctggaac
    12421 agacatcagg accccaaacc attttttgct tttttgatgt ctgaatacgc aataatcagg
    12481 aaatttttta aaaatatatt ctggagacaa attgtatgtt tcattgatgt gatcgattag
    12541 ttcttttttc gttagcatct gcttccatct ctttcttatt gattcgcttt attcaaagat
    12601 accacgtaag aatagaaaaa tgaatacaag tagttgctaa tcaaatactt cgatattttt
    12661 cttttttatc aactcttaaa tgttcaatcc gcctgtgttg gtcttgctac catctactat
    12721 taaaatgttt attattgttt gcccacctat tttttgattt tagtggtatc atttttcaag
    12781 ttcatgatga aattcttatc atcagtaaat gctccagaaa aataaacaat gattgaaaaa
    12841 tcagttgaaa cttgaccacc gtttattttc tccgtattct tagaatagaa gggagtctga
    12901 ttgatgtatt cactaatgaa aaaaatcatt accgaaaaag atattcgacg tcatgtttct
    12961 ttagtagaac aattgctgaa tcatacaaag ataaccgtaa atgaattagc tgaaatcata
    13021 gggacaaccg aacgaacgat tttttctgac cttcaatcta ttcgctctca gctgcccgaa
    13081 ggctgggaca tcatcagcga tcaagcagga atcagtttgc aaaaccagca aaatttatta
    13141 acaaatgacc tttgggagat ttttttcaaa caatcagtca gtgtcgaact gctgaaaaat
    13201 ctgcttttta caaaaaaagt tgctgtccct gattttctag ccgaccatgg gctttcttat
    13261 gggacattga aaagacatgt gactaaaatc aatcagcgtt tagcaagtta cgacttgcag
    13321 atcgatttga cgaaatatac agcttgtatt cttggaaaag agcgtgcgat tcgtactttt
    13381 tatcatcgat tgctgattcc tttcactcat aacaactatt ttttcgagga ttattcgatc
    13441 catgaatccc attattttca atttttaaga aacctcagtc aaactgaact agcggttgaa
    13501 acagaagaga ttttcggaac atgttggttc tttatcaata cgatccgtat aaaagcgaat
    13561 tgccgattag attcttctat ccataccaac agcacactct cctccctgta tgactctgca
    13621 ttgaaaaaat tgtatttaac ggaaggtatt tatcttaaag acactgagct ttcttttgct
    13681 tctttctgct ttctggaaag ttggaattac aacaataact atggacaaga aaccgctcgc
    13741 tgcctgcatc attctccatt tttagaggtc ctcgaaacgt ttgtagagga actagcttca
    13801 gagctgtctc ttgatcaact aaaaaaaaca tctctgactg ataacttggc tctcctcata
    13861 ttaaaatatc atgaatcgcc gatattgatt gaagcattgg accgtcaata ccatcgtttt
    13921 ttagaaacat atgatcagca atatgcacac ttgtatcaac agaaagagaa tttactgaac
    13981 gatctaaaaa aagaaataga aatcaatgaa ccaaattact ttctccaact cttgtctcta
    14041 ctgatccaac aaacgatttt ttctatcaaa ccgaatttgt tcaatgtcta ttttattttc
    14101 caaggagaac cttcatggaa ggcgttcttg cagcaggaat taaaagatta cttaggaaaa
    14161 cgtgtctgct tcttacctat cgaactaacc gatctttcca ctatttcttt tgaaaaaaca
    14221 gatatcttga tttccaattt ccctctagat tctctagata tccctattgt atacatttct
    14281 tctattccaa cgaaaaatga gctcaatcgt ttgactgaac tcactttcaa aac
//
LOCUS       DAPBAF010000061        14202 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.061, whole genome shotgun sequence.
ACCESSION   DAPBAF010000061 DAPBAF010000000
VERSION     DAPBAF010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14202)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14202)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14202
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.061"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(162..2159)
                     /gene="tkt"
                     /locus_tag="RD451_002425"
     CDS             complement(162..2159)
                     /gene="tkt"
                     /locus_tag="RD451_002425"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HDT7567640.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPLGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2261..2512)
                     /locus_tag="RD451_002426"
     CDS             complement(2261..2512)
                     /locus_tag="RD451_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HDT7567641.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2659..3282
                     /gene="lexA"
                     /locus_tag="RD451_002427"
     CDS             2659..3282
                     /gene="lexA"
                     /locus_tag="RD451_002427"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HDT7567642.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3462..3680
                     /locus_tag="RD451_002428"
     CDS             3462..3680
                     /locus_tag="RD451_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567643.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(3969..4481)
                     /locus_tag="RD451_002429"
     CDS             complement(3969..4481)
                     /locus_tag="RD451_002429"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HDT7567644.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4495..6792)
                     /gene="recJ"
                     /locus_tag="RD451_002430"
     CDS             complement(4495..6792)
                     /gene="recJ"
                     /locus_tag="RD451_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HDT7567645.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLIHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPAE
                     FLDLVAIGTIADLVSLTDENRILVSLGIDAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSD
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     VMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(6934..7377)
                     /locus_tag="RD451_002431"
     CDS             complement(6934..7377)
                     /locus_tag="RD451_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1049 domain-containing protein"
                     /protein_id="HDT7567646.1"
                     /translation="MKELKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPL
                     ILVIIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQRE
                     FRNERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7378..8166)
                     /locus_tag="RD451_002432"
     CDS             complement(7378..8166)
                     /locus_tag="RD451_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDT7567647.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETNFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8163..9104)
                     /locus_tag="RD451_002433"
     CDS             complement(8163..9104)
                     /locus_tag="RD451_002433"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HDT7567648.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9281..9868)
                     /locus_tag="RD451_002434"
     CDS             complement(9281..9868)
                     /locus_tag="RD451_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HDT7567649.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(10089..11396)
                     /gene="obgE"
                     /locus_tag="RD451_002435"
     CDS             complement(10089..11396)
                     /gene="obgE"
                     /locus_tag="RD451_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HDT7567650.1"
                     /translation="MFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGGDV
                     ILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAETGA
                     LLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVLAD
                     VGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGLIE
                     GASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLERP
                     QIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNATAD
                     LLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTNFD
                     HDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            11690..12700
                     /gene="gap"
                     /locus_tag="RD451_002436"
     CDS             11690..12700
                     /gene="gap"
                     /locus_tag="RD451_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HDT7567651.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            complement(12785..13720)
                     /locus_tag="RD451_002437"
     CDS             complement(12785..13720)
                     /locus_tag="RD451_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDT7567652.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
     gene            13906..>14202
                     /locus_tag="RD451_002438"
     CDS             13906..>14202
                     /locus_tag="RD451_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7567653.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDVIIGRKER"
BASE COUNT         3966 a         3160 c         2509 g         4567 t
ORIGIN      
        1 ctcaagaaac acaaactaat ccgaagaatt ctttgttttg tcatttaaat gtaacatagc
       61 cgaaaacgaa aagtaatatt gatttattct tctaacacat aaagaacagc tgtctccaac
      121 ttgcagacag ctgttcttat cagtcaaaca attgcttgga tctatgatag ttgattgtac
      181 gtattcacga cattttctac tgtaaatcca aattcttcta aaattttagt gccaggggca
      241 gatgcaccga aatgatcgat tgtaatcgtt gcgccctctg ttcctacgta gcgttcccat
      301 ccaaatgatg cagcagcttc gatagccaca cgtttcttca ctgatttagg aagtacactt
      361 tctttatatt cagaagattg tttttcaaag aggtcaaagc ttggcataga aacaacagaa
      421 acatctttgc ctttttcagc caattctttt tgagctttca cagccaaatc aacttcagaa
      481 cctgttgcaa tcaaaatacc ttctggtgtt tctccttgtg atggagaaag aacatacgcg
      541 ccttttttca ccatttcatc tgctacttct tttgtagaag gcaatactgg aaggttttga
      601 cgactcaata caaggatagt aggcgcatct gttgtctcca tcgctacttt ccaagcagca
      661 cgtgtttcat ttccgtctgc cggacgaatc acttgaacac caggcatgca gcgaacagat
      721 gctagttgtt caatcggttc gtgcgttggt ccgtcttctc cgacagcaac cgagtcatgt
      781 gttaagacgt aaacaacagg agtatgttgg attgctgcta aacgaactgc tggtcttaga
      841 taatcgacaa agacaaagaa tgttccaccg tagatacgag ttccgccatg aagttggata
      901 ccattcatag ccgaagccat tgcaaattcg cggacaccga accagatgtt gcgtccttca
      961 taatgttcag gagtgaaatc tttatctgca gccaccattg tattattgga acctgacaag
     1021 tccgctgaac caccccagaa gcttggtata gctttcgata attcttggat gacttcttta
     1081 cttgaaacac ggcttgcttg actgcttcca acttcataag ttggcaattc tgcatcccag
     1141 ttttctggta gtttgccatc aaaagcatct tcaaattgtt gtgctaattc aggataagct
     1201 tttttataat tggcaaacat ttcattccat gcatcttcag ctttttgtcc ttcttctatc
     1261 atcgtttgat ggaagcgggc agctacttct tctggaacag tgaaatctgg atactcccaa
     1321 ccataaactt ctttagccat cttgatgcca tcttcaccaa gaggagcacc atgaacagca
     1381 gatgttcctt ctttaggagc accatagccg atgactgttt ttacttcgat caatgttggt
     1441 ttgtctgttt cagcttttgc ttcttcaatc gctttagaga ttgcttctag gtcatttccg
     1501 tctttcacta agatatgttg ccagccatat gcttcatagc gagcaccaac gttttctgtg
     1561 aaagcttttg aagttggacc gtctagtgaa atatcgtttg aatcgtataa aacgatcaat
     1621 ttccctagtt tcatatgacc tgccatcgaa cttgcttctt gagatacccc ttccatcaag
     1681 tctccgtcac cgcatattgc atacgtatag tgatccatca cattaaagtt ttctttgtta
     1741 tacgttgctg caaggtgcgc ttctgccatt gccataccga cagccattgc aatcccttgt
     1801 cctaatggcc ctgtagtggc ttctacacca tctgtatgat gtacttcagg atgtcctggt
     1861 gttttagaat cccattgacg gaattgtttc aaatcatcga ttgtcacttg atagccagct
     1921 aaatgaagca agctatacaa cattgctgac ccatgtcctg ccgaaagaac gaaacggtcg
     1981 cggtcagccc agttttttga tgtcgttgga tttactttca ggtgttttgt ccataacgca
     2041 tatgccatag gtgctgcgcc catcggcaat ccaggatgtc ctgagtttgc tttttggact
     2101 gcttcaatac ttaatgtacg aattgtgtta acgccaagtt ggtcaatttt gtcaaacaaa
     2161 ataacccctc ctattaattt aggttttttt tacctttatt tcttacactt tcattctata
     2221 agatgtcaca cgaaaaagca atctttttca gtatttttta ctaaaagttg tcatttcggt
     2281 tgtgtaagcc ttttttcttt tggatttctt ttaatttttc cggggtcacg tcattgccct
     2341 caggatcgac gactttcatt ccttcgatat gatgacgcat accggaacga aaagcttcca
     2401 aatactcttt gcgcaagttg atttgttctt gttcttcggc ttttgagaga ccattttcct
     2461 tctttttacg tgcaagttca ttgatccgct ctattttttc aggtgacagc atgctcagcc
     2521 ctccttttac tctccttcat attatataaa aactgaaaaa aaaacaacta gataaactaa
     2581 ataaaatacg aacattcgtt tgatttagcg ctttttatat ggtactattt atttatcaag
     2641 tgaaagaagg tgtaccttgt ggcccgacaa actgaatcaa gacaaatcga agtcttacga
     2701 tatatccatg aacaagtaac ccaaaaagga tacccgccga ctgtccgtga aatcggggaa
     2761 gctgttcagc tttcttctac ttctactgtt cacggtcatc ttgcacggct tgaaaaaaaa
     2821 gggtttatcc aaagagatcc gacgaaacct cgtgcaatcg agttgacaaa acaaggttta
     2881 gaaaagattg ggattcgtcc aacaactatt ccagtacttg gcgtcgtaac agctggagaa
     2941 cccattttag cagtagagga tgcttcagac ttctttccaa tccctcctaa tctttcttcc
     3001 gaagaaggca gtctctttat gctgacaatt cgtggagata gtatgatcaa tgctgggata
     3061 ttggatggtg acaacgtgat cgttcggaag caagaaactg ctcaaaatgg cgatattgtc
     3121 attgcaatga ctgccgagga cgaagcgact tgcaaacgat tctataaaga aaaaaacttt
     3181 ttccgtctgc agcctgaaaa cgacttgctc gaaccaatca tcttagatca agtatctata
     3241 ttaggacgag tagtaggact ttatcgtagt catatctatt aattgctact aattaaaaga
     3301 aaacttttta aaaagagttt gagacgttgg tctcaaactc ttttttcgcc cgggttcttc
     3361 ttctttcaaa tttttatcac ttccctcttt acaaaccgaa caaatattcg tatactaaat
     3421 atacgaacaa ttgttcgcat aaattaaaga ggtgagaatt catgaaatca atgagacgtc
     3481 ttggcttagt attaactgtt ttgtttttag gtattattat tggtaatttc ggcatacgtc
     3541 cagctttact tgtgtttgtt ccgttattta ctttgtggtt catgttgtgg gatgaaaaga
     3601 agtaccgtca atctgagcgg cgcagaattc atgaagatca tttctatcat gagccctact
     3661 acagatccag gcaatcataa taaggattga ctgctaatta ttcaaaagac aagaagttaa
     3721 acttttacgg gggtgtgaca aaaatcggtc acatcctttt tttcgaataa acggtgttct
     3781 aaagccagtt tttcggtatt aagtcaaatt gcggaaaaag tgatttttta aacttctact
     3841 ggtctttgct tgtttccatt tataaaaaaa tagcgaccct caaaagtcag atagagaatc
     3901 tgacttttga gggtcgcttt aaaatcgctt ctttaagaat aacatcaaga atagcttctt
     3961 ttttctgctt aatattccat taatgtaatg atgtcatatc ctttgatttt gtcgcgtcca
     4021 tggagatcca tcaattcgat caaaaatgcg cagcctacga ctacaccgcc taattgttcg
     4081 atcagttcga tcgtcgcttt gattgttcct ccagtagcta gcaaatcgtc acaaatcagc
     4141 acacgttgac ctggtttaat ggcatcctta tgcaatgtca atgtatctgt tccatattct
     4201 aatccataag tcacttcgat ggtttctcga ggtaacttcc cttttttgcg gactggggca
     4261 aaaccgactc ctaactcata agcaacagga catcctacga tgaatccacg ggcttctggc
     4321 ccaactacca tatcaattcg tttttctttt gcataattta cgatttgttt agtagcttcc
     4381 cgataagcgt caccatctgc catcagtggg gaaatatctc gaaacacaat tccttttgac
     4441 ggatagtcgg gaatactggc aatataatct tttaaatcca ctctttgttt cctcctaggt
     4501 tgttaaccat ttctttatgg taggaatatc gctcaaaagc aaaaattcct caactttgat
     4561 tttattgagc cgtcgctggt ataatctgct ctcagtcaaa ggatgacttt ctgggctagc
     4621 gactttttgt aaaacaccgt tctctattgt aacaaatttc aattcaaaaa acacctgtat
     4681 cataaaaatt aataattttt cagggatacg caaatattga gctattgctt ttattttatg
     4741 acgtatatca attcgttctt gagaatggat caatttaaac aattttgcgt actgttctct
     4801 tgtgcctacc ccattcaaat aggcctcatc aggtgaaatc cccatcagat aaacacgatt
     4861 gaatgaataa gaccgaaaaa cttctttcag atccgctaaa tcatctggac aatccataac
     4921 aactagagag tttggttttc ttttttcaat tattgccttt acagaatcta gtccttcgaa
     4981 aacaatcgca gcttcctgga taatctcagg cacgaatttc aacgtcgaag aatcaaatgc
     5041 taaataaagg ctaccttccg acgttcggct ctgttcacgg aaacgttttg cccgccaatc
     5101 aaatacttgc agaccaccca cagaaaaatc agataccatc agctgcggtt tcttacgccc
     5161 gttccattca ttgatcgaaa gctttcctac cacatctacc tgattattca gcagttcttc
     5221 ttcttgagta ccaaaaccaa aagcgaccgc atcaagctga ctcgatgcat cggaaaggac
     5281 aaatttcaga tgctgttggt ttgctccgat tcttttgata ttttctgctt ggacttgtcg
     5341 aaataaaaac tgaggcaaag gattatccgt accaaatggc gccaatagtt tcagctcatc
     5401 aattcgctct actgttactt catttggcag caatacttca tcaattctca actcaggccc
     5461 tctcatcaag tcaatttgat gatcgactat atattggttc atcttctcct gtagtatagt
     5521 gacattttca cttggcatcg ttaaaccgac tgctgcatga tgtcctccga agtaagtaaa
     5581 taaatctcgc atctggtcaa gcatttcaaa aagattcaag gcttcaatac tacgtccaga
     5641 tcctttagct gatccatctt cttttaaagt aaggacaagc gttggtttac ccgtttcatt
     5701 cattattttc ccagcaacaa tgcccaaaac gccttcatgc catcctcggt ttaccaatag
     5761 atggatatga ttctccttat tgaccatcgc taatgcttct tgtgttatct gctctacgat
     5821 tgcttttctt tcttcattga tctcattcaa tttttttgct tgaacggatg cttcctcttc
     5881 atcaaacgtc gcaagtaacg agacggcagg acgtggatcg cccatccgac cgattgcatt
     5941 tagtctggga gcaatcgaaa aaccgatcgt tgtttcgtct gcgtccctca tttttacgcc
     6001 gctttcttca aatagcgcct gaagtcctat ccgttctgaa tgatgaatgg catcgattcc
     6061 taatgaaaca aggattcgat tctcatcagt caatgaaact aaatcggcga tcgttcctat
     6121 cgctactaaa tccaaaaatt ctgcaggcgg ttcttccaat aatgcagaag ctactttgaa
     6181 tgctactccg actcctgcca aatctggaaa tggatagtgc cccgctggat gacgagggtg
     6241 aacaatcgca taagcgtctg gtaaattctc aggtagttcg tgatgatctg taatgatcac
     6301 gtctacacca gcttgctgag cgtatgctac cgcatcattt cctgctaccc cgttatcaac
     6361 agtgatgatc aactggattc cttcttcgat cttttcttgg tataccgatt ggtttggtcc
     6421 atacccatgc tcaaatcgat ttggcaggaa tacttctact tctgcaccaa gtaattccag
     6481 tgtttctttc attaccgttg cactggtgat cccatctgcg tcataatcac cgtaaacgag
     6541 gattttttct ccactgatta cagcttcttg gattcggctg attgctttat ccatatcgtg
     6601 tatcagatac ggatcatgta attcttgttc ctttggatgt aaaaatcggt tgatatcctt
     6661 ttcctcatgg taacctcttt gccacagtaa cttaccgaca aatggagata atttcagttc
     6721 acggatcatt tggagaaagg attcagaagg ctctgtctcg cttaacttcc aatcaaaatt
     6781 tgcttgtctc actttctcac tcctaactta gttattatag caaaggaaat cagcaaaaaa
     6841 aagcagaaag aaagaataaa aacagatcag atccgctaga cagatgttca gcaggacctg
     6901 atcttttgta cgaccattta tgaaatatcc ctattagtca aaataattga agctttgttt
     6961 gggcgattga gttttttgtt cttccggcgc tttcaattga ctgatttgtg cggttttcgc
     7021 ttgtaactcc gcctgataag cagcttccaa ctccgcacgt tcgtttctaa actcgcgttg
     7081 ctgttcttct tttgcttctt caattttctt ttgaagttct gtttgatatt ctgacatttc
     7141 ctgagtcagc tgtttgattt gctttttttg ctgccatagt gttgccgaag cagtcaaaaa
     7201 tacaatcagt gcaccaatca gcgcagaacc gatgatcact aagatcaatg gcgcagaaaa
     7261 ggaagtgaag ccaaaactta caggaacatt tttattgttc aatacagcaa aaagaacaat
     7321 aatcaaaact aaaacaaatc caagaatcac attgctttgc tttttcaatt ccttcaccta
     7381 ctttttgtta aaaattccgc tggctaaata atcaccaatc gttggaaaca gcgtataaaa
     7441 ttttgatgca acttctaaaa taaacggttg attgatttcc cgttttggat gtctcatatt
     7501 gcggacgatc atttttgcca acttggcagg ttctaaaacg atttgtccga ctttttccaa
     7561 atagcttccg cttggatcag ccttatcgaa gaaatttgtc tcgattggac ctggattcac
     7621 tgtcgtaaca gctacgccaa gtggtttcaa ttctaatcgc aaagcgttgg agaagccaag
     7681 gactgcaaat ttcgtggcag aataaaccgt tgattttgca gttgccattt ttccagccat
     7741 agaggcgata ttaatgatat gaccttgtct tctttctgcc atatcgatcg caaatttttg
     7801 tgtcaaaacc atcattccta agatgttgac ttcaaacata tcgtatgctt ttccaaggtc
     7861 gaatgtaagg aagtcttcga aaatcccaaa acccgcattg tttaccagaa tatcgacgcg
     7921 cccgacttct tccatcacct tttcatataa ttcgtccacg ctttcaggat tgctgacgtc
     7981 taccttgaaa gcataagcct ctttgccgct caagcgtctg cactcgtctc tgacaccttc
     8041 tacaaatgcc attcttcgtg cgcaacttat aacgattgct ccttgctttg ctgcttcata
     8101 acagatttgt gcgcccagac cgcctgaact acctgttact aaaacaactt tatcttctaa
     8161 attcatgcct cttcctcctc gcgaaatgga atctcaatgc tatcaaaatc tttcataatc
     8221 gtcgtgtttt caaacacttc ttgtgcttct ttttcaagct ctaaagctgc ttttcctaaa
     8281 tatctcgcac tgatatgagt aagtagcagc cgttttgcct gcgcttcttt tgcaacttca
     8341 gcagcttgat gagtcgtgga atggaaatag ttgtgcgcca ttcttgcttc atctttatta
     8401 aatgtgcttt catgtaccag aatatcgcta ttttccgcaa gcacaacgga attatgtgtt
     8461 tttctcgtat cgcctaaaat agtcacgatt cgtccttttt tatctggacc tacgaaatct
     8521 tttccattga tcgtccgccc atcttctagt tggatcgttt caccttgctt cagtttgccg
     8581 tacagtggtc cagctggaat acctaattct tttagacgat ccacctgcaa ttctccttta
     8641 tgatcatgtt caaccacacg ataaccaaaa ctgtcgatcc catgatttag tttttttgta
     8701 taaacagaaa attgctgatc agtaaaaatc ggggctgttt catttagctc aatgaatttc
     8761 agcggataac ttaaacgcgt ttgcgaaata cctaaagaga cttttatgta ttcctctatc
     8821 ccttttggcc cgtaaatctc taatggcgta tccccacctt gaaatgaccg gctgctgatg
     8881 agcccgggaa gtccaaaaat atgatcgccg tgtaaatgtg taatgaaaat tttaccgatt
     8941 tttctcggac gaatagtcgt tcgcaaaatc tgcatttgcg tgccttcgcc acagtcgaac
     9001 aaccaaactt cattgcgctc gtctaaaagt ttcaatgcta tacttgtcac atttctatgt
     9061 tttgcaggaa cacctgcacc tgttcctaaa aattgtaatt ccataatcta cctgactttc
     9121 tttaagttcc tctttaattt tagggtaaaa agaagggata atcaaccgta agtcgagaat
     9181 gggttcaaat taaaaataac gttctaaagc gatagcgttt tctttgaaaa ttactataaa
     9241 aacagcagcg aacccgtttg agatcctctg ctgtttttta ttaatttgaa gatccagaac
     9301 tttcattgtc gttggaagtt tgcggatgtt tgtccttcca agtcttttgt gcagcttctt
     9361 tcgcatgatt ttcagcttct ttcgcatcat gcacatcttt ttcgacatct tcataatcca
     9421 agcgagtaat ttctccgcct aattccatca ttaccaattg attcagtggg cgattgtcct
     9481 cttcatcagc aatcaagatc agtcctgtag ctccttcacc gattttattt cctacaaagt
     9541 cgaacacggt ctgggcatct tttatttctt tggcatcttg tgtcgcaccg atcattcctc
     9601 cggcaaacca tcctaataaa atccctagcg gaccacctaa tacaccaacc aacattccga
     9661 ttaatccacc cgtagaagat ttgttattac cggtaaagtc gataaaatct tctattttga
     9721 attgatgtgt cccattagga tcatggctga caactgccat ctgttctcct ttaatcgaac
     9781 gaacagcatg taactttttg atttctgaaa atgcctgata tgcctggctt tctacttgaa
     9841 aatttaaaat gattactcgt ttgctcatta aaaacgcccc tttcatacct tcttgttatt
     9901 tattttacct ttaattgaaa aataagaaaa gaaaagcact ctttttttcc aataaaatag
     9961 ggctgtgaca aaagtcgtat cacagctcct ttttccgaat aaacggcgtt cttgaagctg
    10021 atcacttctg tcacaacctc ccttaaatct gaatctatat tttttggtat ttgtttttat
    10081 ttgcttgcct attcgacaaa ttcaaattca aactcaccga tacgtacaag gtcgccatct
    10141 ttcgcaccgc gtgcccgaag agcttcatcc acacccatac cacgtaattg acgagcaaaa
    10201 cgcatcactg tttcatcatg atcgaaattc gtcatttgga ataatttttc gatcttctca
    10261 ccagataaga tccacgttgc atctgaatca cgatcgattt ggaactcagg accttctgga
    10321 ttgaatccat agtgtacagt ttcttcttcc agttcttctt cgtacaatgg gaattctggc
    10381 gttacttcta acaaatctgc tgtagcattc aataacgcgt ccaatccttg tcgagtcact
    10441 ccagaaattg gaaatactgg gatgtcatca gcaaattcat cttctttttc cttgttcagc
    10501 tgttctttga atttcactag attttccggt gcatccggca tatccatttt gtttgccacg
    10561 atgatttgcg gacgctctag caagcgtaag ttataagtag ataattcttt gttgatggca
    10621 agatagtctt cataaggatc tcgtccttcc atcccactca tatcgatcac atgtaaaatt
    10681 actcgtgttc tttcgatatg acgaaggaat tgtgtaccca gcccaacacc ttgcgaagct
    10741 ccttcaatca agcctggcaa gtctgctgcg gcaaaacttc tgccatcact tgtagtaacc
    10801 attcctagat taggtacgag cgtcgtgaaa tgataagcgc cgatttttgg acgagcagat
    10861 gaaataacgg atagtaaagt cgatttcccg acagatggaa aacctacaag tccaacgtct
    10921 gccaatactt tcaattctag ttcgattttt cgctcttgtc ctggttcacc gttttcagca
    10981 atttccggtg caggattccg aggagaggca aaacggatat tccctcgtcc accgcgtcca
    11041 ccttttgcca caactagtgt ttgaccattt tcaattaaat ctcctaaaag agcaccagtc
    11101 tccgcatctc ggacagtggt tccttgtggt actttaacat aggtatcttc tgaaccacga
    11161 ccgtgcatcc ctttactcat cccattttca cctggctgcg ctttgaaatg gcgattgaac
    11221 cgaaaatcca tcaatgtacg taacccttca tcgacgatca agatgacatc gccgccacga
    11281 ccaccgtctc cgccagccgg tccgccgtca ggaacgtatt tttcgcgacg aaatgcaacc
    11341 attccgtctc cgcccttgcc agctttcaca tcgatcgtta cttgatctaa aaacatggac
    11401 ataattaagt cctcctatta ttcatttatt tatttgactg cctgaatttc cacaataaac
    11461 aaaagtctta cttattttat cggtgaaatc tgattttgtc tatcatttca gcaaaaagat
    11521 tgtttacctt cttctttttt tatcatttgg taaggtttcc aacctttttt ctgctaccaa
    11581 gtataatttt ttgacaaaat attctttgcg tagcagaata acagtgtatt aattgtatta
    11641 attgaggatg ccgtttcaca gcacccctaa taaaggagga acttttgata tgacagtaaa
    11701 agtaggtatt aacggatttg ggcgtattgg ccgtctggct ttccgccgca tcaaagaagt
    11761 ctcagatgat attgaagtag tagcaatcaa cgacttaaca agtccaacta tgttagcaca
    11821 attattgcaa tttgactcta ctcatggtac ttatcctggc acagttactg caacagaaga
    11881 ctcaatcgta gtggatggcg aagcaactcg tgtttatgca gaacccgacg caagcaaaat
    11941 cccttgggca aaagaaaacg gtgtagatat cgtactagaa tgtactggtt tttatacatc
    12001 tgaagaaaaa gcaaaagcgc atttagatgc tggtgtcaaa cgagtagtta tttctgcccc
    12061 agctggtgct atgaaaacca tcgtctataa cgtcaatgat gatacattag atgaaaacga
    12121 caaaatcatc tcagcaggtt catgtacaac aaactgttta gcacctatgg cttatttctt
    12181 aaataatgaa tttgggatcg aagttggtac aatgacaaca gttcatgcct acacttccac
    12241 acaaatgctc ttagatggac ctgtaaaagg cggtaatttg cgtgctgctc gttcagctgc
    12301 tgacaatact atcccacatt ctactggtgc tgcgaaagca atcggcttag ttatccctga
    12361 gctacaagga aaattacaag gacacgcaca acgtgttcca gtcgttgatg gttcattaac
    12421 tgaattggtt tcagtattga aaacaaaagt aactgctgat caagtaaacg aagcaatcaa
    12481 aaaacacaca gttgacaatc cttcattcgg gtatgatgac cgtcaaatcg tttctagcga
    12541 tgtcattgga acaactcaag gttcgatctt tgacccaacg caaacagaag taacaactgc
    12601 tggtgatttc caacttgtta aaactgttgc atggtatgac aatgagtatg gatttacttg
    12661 ccaaatgatt cgcttactag aaaaattcgc taacttgtaa tttgatagat caatcgataa
    12721 aagaagcctt tgactggatc cagtcaaagg cttctttctt ttcatcccct acttttaaac
    12781 tcgttcaatg aacatattgg cttaaaaatt gttggactac ttgctgatat ttttcaggat
    12841 ctgtcttgta tgcttccgca tgctcggctc cttttacaac atacttttct tttggtccct
    12901 tcgttgcacg atagacctta tctaacattt caaatggtac aaatgtatct tcgtctccat
    12961 gtataaagag cattgggcgc tggtttttct tcaattgttc cactgcattt gcttcaccga
    13021 aaaagtagcc agcacggact tttgtcacta gactcgttac ttgcataagc ggaaatgctg
    13081 gaagactaaa catatcgtct agctgataag caagctcatc atgaacggaa gaataaccgc
    13141 aatcttcaat gattgctttc acattatctg gtagtttttc tccgctagtc atcataactg
    13201 ttgctgctcc catgctgaca ccgtatagaa cgatttcttg cgattttcca ttgttttcta
    13261 gcactttgtt tatccactgt acatagtctt tacgctctgg ccatccaaat ccaatgtaat
    13321 ccccttcgct ttttccatgt cctcttgcat caggaacaag gacattgtaa cccatatcat
    13381 gaaacatctt tgcgtaattg gtcatcgttt cagcgtttcc catatagcca tgagccacaa
    13441 gagctgtttt ttcacttttc gtttcagcag gaagataaat cgctgataat ttcagaccgt
    13501 cttttgaagt gatggtccaa tcgcttcggt tttcttttga actaaaccat ttatgtgcat
    13561 ccgtttcttt ggatgtctgt gttgtaccag gtgtatcttc gtctaaaaag tctttctcag
    13621 aaggcacaac agcataatta taaaaataat tccctgcaaa cactaacgca acaatcagag
    13681 ctaaagcgac gcctaaaagg attttcatcc aaagtttcat aaatcatcca tctcatttct
    13741 cttttttcat ataaccttga attagtataa tcaaagaatc tctactatgc aatgttcatt
    13801 tttataaccc gcgaattgta aaattaagtt agaaaaataa aaaggcattt atggtacact
    13861 caaattgtat ttccgacgaa agaaaacaaa ggagtgtaac cataaatgac ctacaaacat
    13921 cttaccatag acgaactgac aatgatagaa tcatattatc ttcaacataa taagccggtt
    13981 gaaatcgcta accgaatggg acgtgctata caaactattt ataatgtagt caataagttc
    14041 aagcaaggca agactgctct tgattattgg caccagtata aagaaaataa gaaaaaatgt
    14101 ggtagaaaag tcattcaatt acctgctcat gaagtagatt acattaaaga gaaagtcact
    14161 cttggttgga cgcctgacgt cattatcggg cgaaaagaaa gg
//
LOCUS       DAPBAF010000062        14202 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.062, whole genome shotgun sequence.
ACCESSION   DAPBAF010000062 DAPBAF010000000
VERSION     DAPBAF010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14202)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14202)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14202
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.062"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(718..3867)
                     /locus_tag="RD451_002439"
     CDS             complement(718..3867)
                     /locus_tag="RD451_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HDT7567654.1"
                     /translation="MKISHREEAEVEEQLIRVLGEGHNQWTYRPDLKSEEDLWVNLRQ
                     KIISNNQAELNDFPLTDKEFETIKTELLLRTKTPFDAAKWLKGENGMARITIEREDPQ
                     LGSVSLILYSNQDIGGGISTYEVVHQIAKRGSNIEARDRRFDVTLLINGLPIVQIELK
                     QVTAKDSFYQAFNQIKKYAEEGMFRNNIFSTLQLFVVSNEQTTRYFANALPKDLHPKF
                     LFSWRTKDNKKVENLYEFCKQVLNIPDAHRLIADYTIVSEDQDNKILMVLHPYQVHAI
                     QALFIAANKHQSGYVWHATGSGKTLTSFVSTKLLARKSGIDRTIMLVDRKDLDNQTTT
                     EFTKFASEFNTGISSGNAKANSLIVGTGSAKELSETLLADANANVVIITTRQKLDAAL
                     KYAKKQEEKKGTNRFQKLMGQHIVFVVDECHRALSAENMEEIKKMFPKSTWFGFTGTP
                     IFPENRKQAKGQLARTTHDQYGEVLHTYTIKNALEDGSVLGFQVEHENTVEPTSLENK
                     IYRKLKEVETYAEYSPEQINRMIDQMEPVKKESYLDPTVFEADEHIQKVIHKMFRPDN
                     AYTKFDFRNGRPTKSAILTTSSIDMAKKYYRAIKEMTKEPDWLTKEFPNQPIREGRTM
                     EDPDFPRIAITYSLEENSRDSSVQQEEMQKIIEEYNQYYDTSWSLADIERYNGDINNR
                     LARKRAEFKQFGKQIDLVIVVDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTY
                     PEKTKGLIVTFRKPATMEKNVEDATKLYSEAKEESGLIYPSYQESKKRFKQAYGKLKE
                     VSSMESIDEHTPLEIRIEYVKAFQELNRAYESLVTYDDYNDDMVKSSTLNNQIQLLEE
                     QIGVYETVKGSLIEEEPEKEGEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSD
                     AREEIEKALAKLNKTEGVKEVYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDDLIHV
                     FSNEWFVSEKELHASNLQYMPGEDPIPNMKAIINSKDYEGYKANHPEAKPFKYPQEMK
                     RAWRKMLDDELIPLENELR"
     gene            complement(3881..5125)
                     /locus_tag="RD451_002440"
     CDS             complement(3881..5125)
                     /locus_tag="RD451_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HDT7567655.1"
                     /translation="MSNDIQPEIRFPGFTEAWEQRKFECLLDKKDGVRRGPFGSALKK
                     EFFVSNSNFVVYEQQNAIYDNYETRYKITEKKYNELIKFKLEPGDFIMSGAGTIGRIS
                     RVPKQIKPGVFNQALIRLRINKEITDSEYFIQFIRADFMQRKLTGANPGSAITNLVPM
                     SEVKKWIVQFPILEEQKKIGNFFKQLDDTIALQQRKLDLLKETKKGFLQKMFPKNGAK
                     VPEIRFPGFTEDWEQRKFKEFSKKTGKKNTKDLDFPAYSVSNKAGLISQTEQFDGSRL
                     DDLEKTNYKFVEPNEFAYNPARVNVGSIAFNNLGMTVIVSSLYVVVKMSEDLDNEFIL
                     QFIKSPTFIKEVKRNTEGSVREYLFYENFANIKFPFTRNKEEQQKIGAFFKQLDDTIA
                     LHQRKLDLLKETKKGFLQKMFV"
     gene            complement(5118..6710)
                     /locus_tag="RD451_002441"
     CDS             complement(5118..6710)
                     /locus_tag="RD451_002441"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HDT7567656.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAISPEYLFNVLA
                     DQAKQATFQLNDLNKAFVQLASTYNQFNGLFDDVDLQSKKLGTDEQQRNVTITEVIKK
                     LNDVEVLGHDGDVIGDAYEFLISQFASEAGKKAGEFYTPHMVSDMMAQIVTLDQKERR
                     FFSVFDPTMGSGSLMLNVRNYLTHPDNVKYHGQELNTTTYNLAKMNLILHGVDAEEMN
                     LRNGDTLNKDWPTDEPYTFDAVVMNPPYSANWSADTTFLDDSRFNRYGKLAPKSKADF
                     AFLLHGFYHLKETGTMAIVLPHGVLFRGAAEGVIRQKLLEDGSIYAVIGMPANLFFGT
                     SIPTTVIVLKKNRQTRDVLFIDASREFVKGKNQNKLSEENIQKILETYAERKDVEKYA
                     HLANFDEIKENDYNLNIPRYVDTFEEEEPIDMVHVGNDIKKIRQEQQVLEKELLEAIS
                     SLQTTPENEAWLQGALEVFKHE"
     gene            complement(7220..7945)
                     /locus_tag="RD451_002442"
     CDS             complement(7220..7945)
                     /locus_tag="RD451_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567657.1"
                     /translation="MKKKKLLWICLAILLIIGGIEIFTTYRLKTNQPKQYVSDMLNII
                     EEIDSEMKAFSKTSMDLGERYDFKGFMEDKMDEVSSREIPEGTPKAVRDTKDTLLEAI
                     DNVNTALLTNDVKLLEQGQLCFSIAQAIYTEFLDGNIKEKSLNEKLNSFVETYTAIPP
                     TWKLVNEDKGITINTDTEISTDAQSLSDLLANLTGISNAVTEKVGKDIPLRLLENGKK
                     DYSVVFKNGQVTDYNEVFKKVIE"
     gene            complement(8099..8425)
                     /locus_tag="RD451_002443"
     CDS             complement(8099..8425)
                     /locus_tag="RD451_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567658.1"
                     /translation="MNKVNMNKKFVIIGIVVLAIIGIIFSRMTGSSGLEKSSVPLVTQ
                     ILQEQYNLNRTCDDVTITHDNGDNTYRAKATLDNGSAININVEYYPKKDRVYVEIPYT
                     EVLMLN"
     gene            complement(8462..8827)
                     /locus_tag="RD451_002444"
     CDS             complement(8462..8827)
                     /locus_tag="RD451_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HDT7567659.1"
                     /translation="MYCRKCGKEITNESKYCQFCGALQETDETTGTDTVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVSLAFIPVVFGAVAVIMGYLYREKDEQMGTILM
                     IAGVAGAIFGVLLGMSMSY"
     gene            complement(8864..9079)
                     /locus_tag="RD451_002445"
     CDS             complement(8864..9079)
                     /locus_tag="RD451_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7567660.1"
                     /translation="MKKVSNLSRYRKEKGLSQTELAKKMNVTQQCVSSWQTGRTIPKP
                     YQMKMLSEILSVPINELFSDVFNKVNS"
     gene            9208..9543
                     /locus_tag="RD451_002446"
     CDS             9208..9543
                     /locus_tag="RD451_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7567661.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAKKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVDIDYEEEFLALYRSLSTEDAIRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            complement(9619..11616)
                     /locus_tag="RD451_002447"
     CDS             complement(9619..11616)
                     /locus_tag="RD451_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567662.1"
                     /translation="METSMINIPIYVDKEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSIEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSSYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFKHKRSNVYRLDVFNATSVIQKLNEDILPLLEKFHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELINTVC
                     ERLRNVRDNSVKNALIENRGYFVKQGFTLERASKDIKKLYNVKASSSFLVYLAKGAGI
                     DEVIKELILSGVELVPIYQFTSVTRDDGRRVRNRRDPIILN"
     gene            complement(11714..11989)
                     /locus_tag="RD451_002448"
     CDS             complement(11714..11989)
                     /locus_tag="RD451_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7567663.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
     gene            12221..12955
                     /locus_tag="RD451_002449"
     CDS             12221..12955
                     /locus_tag="RD451_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7567664.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIVEEFDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDN
                     INKLEQTISSIGKKYTKKKMKGGDTI"
     gene            12994..14136
                     /locus_tag="RD451_002450"
     CDS             12994..14136
                     /locus_tag="RD451_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDT7567665.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
BASE COUNT         4398 a         2751 c         2148 g         4905 t
ORIGIN      
        1 ggactaatac aggtagtcct cttttttgtt attttgatat tctaaatcat tttttattgg
       61 attattccct tgttcgatat agacccaaat tgatctatca ataattatca aactgagtca
      121 tatagagaca aaaatttcaa aaatgacctg ttaaatggtc atcgaatatc atttaaaatc
      181 aatacgacgg agtcagacac ggagtcaaaa caagcccgct gagagtaaaa aatatataca
      241 gtcccatagg taaagtgcca caggactgta tattttttta tttgagatta cctgaaatga
      301 ttccatttac tttttatctc attttttcct actagttagt atcaaatact ctcctatttt
      361 ctcaataaac tattttgggt tacatggtat ctgaaacagc taaaaccttg tcattacagc
      421 aaaaaatcac tttatctccg tttcatttca gatacatttc acttaagcgg attccaaaaa
      481 aacaaaagaa aaaggaaccc ctagttagcc tatgcttttt attggttcct ctcaaaacac
      541 ggtcatataa caacggggtg gggtaaatga atgaaaaagg tggaggaaac attattcaat
      601 agctgtctta aatacttcgt tataaaatgt gaacaaataa aagacatcta tccctatttt
      661 ctacacttcc actttactac catctttgaa tcgtacaatt ttcttaactc ttctcgttta
      721 cctcaattca ttttcaagtg gaatcagctc atcatctaac attttacgcc atgctcgctt
      781 catttcttgt gggtatttaa atggcttcgc ttctggatgg ttggctttat atccttcgta
      841 atccttactg ttgataattg ctttcatatt aggaattgga tcttcacctg gcatatattg
      901 cagattagaa gcatgtaatt ctttctcaga aacaaaccac tcattggaaa agacatgaat
      961 caaatcatca ctcgcttgtg taaaatagcg acgtttaatg acaaagatat cttcattact
     1021 atctaaagtc cccacatcaa acgcatttaa aatttgtcgg taaacttctt tgactccttc
     1081 tgttttattc aatttagcca aagctttttc aatttcttct cgtgcatctg aactattcgc
     1141 cgcataagtt cctagtaatt gatcaatata agtagaatca atatcataca acttcgtggt
     1201 attttcacta taaaattcga tcgtggaaaa atcttctccc tctttttctg gttcttcctc
     1261 tattaatgaa cccttcacgg tctcgtacac gccaatttgt tcttccaaaa gttgaatttg
     1321 attgttcaag gttgaagatt tcaccatgtc atcattgtaa tcgtcataag tcactaacga
     1381 ttcataagca cgattcaatt cttggaatgc tttgacgtac tcgatacgga tttcaagtgg
     1441 cgtatgttca tcaatggatt ccatggatga aacctctttt aacttaccat atgcttgctt
     1501 gaatcttttt ttggattcct gataacttgg ataaatcaaa cccgattctt cttttgcttc
     1561 tgaatacagt tttgtcgcat cctcgacatt cttctccatt gtggctggct ttcggaaagt
     1621 aacaattagt ccttttgttt tttctggata cgtacggttc gtacgtgaaa aagcttggat
     1681 caatcctgca tactctagat tacgatccac aaatagggtt tgaatcgtag gtgcgtcaaa
     1741 acctgtcaat agacgatcca ctacgatcac taaatcaatt tgtttcccaa attgtttgaa
     1801 ttccgctctt tttcgtgcca aacgattatt gatgtctccg ttataacgct caatgtctgc
     1861 taatgaccag gaagtatcat aatactgatt atattcctca ataatttttt gcatttcttc
     1921 ttgttggaca cttgaatctc ggctgttttc ttctaatgaa taggtaatag cgattcgtgg
     1981 aaaatcagga tcctccatcg ttcttccttc acgaatgggc tgattaggaa actcttttgt
     2041 taaccagtca ggttctttcg tcatttcttt gatcgctcga taatactttt tggccatgtc
     2101 aatggaactc gtggttaaga tcgcagactt cgttggacgg ccatttcgaa aatcaaattt
     2161 tgtataggca ttgtctggac ggaacatttt atgaatgact ttttggatat gttcatctgc
     2221 ttcaaaaaca gtagggtcca aataactttc ttttttgaca ggctccattt gatcaatcat
     2281 acgattgatc tgttccggtg aatactctgc atatgtttct acttctttta atttccgata
     2341 gattttattc tctaatgaag tcggctccac ggtgttttca tgctctactt gaaatcctaa
     2401 aaccgagcca tcttctaatg cattcttgat ggtataggta tgcaagacct ctccatactg
     2461 atcatgggtc gtacgtgcca attgcccttt ggcttgtttc cgattctcag ggaaaatcgg
     2521 tgtacctgta aagccaaacc aagtggattt cggaaacatt tttttgattt cttccatatt
     2581 ttcagcactt aacgctcgat gacactcatc tactacaaac acgatatgtt gccccattaa
     2641 tttttggaag cgattggttc cttttttctc ttcttgtttt tttgcatatt tcaacgccgc
     2701 atctagcttt tgacgggttg taataatcac aacatttgca ttggcatctg ccaacagagt
     2761 ttcacttaac tctttggcac ttcctgttcc cacgatcaag ctattcgctt tggcgttccc
     2821 ggaagaaatc ccagtattaa attccgaagc aaatttcgta aactctgtgg tggtttgatt
     2881 atctaaatct ttgcggtcca ctaacatgat cgtccgatcg atccccgatt ttcgtgctaa
     2941 aagcttagta gatacaaaac tagtcaacgt ttttcctgaa ccagtcgcat gccacacata
     3001 tcctgattga tgtttatttg cagcaataaa caaggcttga atcgcatgta cttgataagg
     3061 atgtaacacc atgaggattt tattgtcttg atcttcactg acaatcgtat aatccgcaat
     3121 caagcgatga gcatccggga tatttagcac ttgtttgcaa aactcatata agttttctac
     3181 ctttttatta tctttcgttc gccaactaaa taaaaactta ggatgcaaat cctttggtaa
     3241 ggcatttgca aaataccgag tggtttgttc attggaaacc acaaacaact gtaaggtcga
     3301 aaagatattg ttccgaaaca taccttcttc tgcatatttt ttgatttggt taaacgcctg
     3361 ataaaaacta tcttttgcgg ttacttgttt cagctcgatt tggacaatcg gtaatccatt
     3421 gatcagtaag gtgacgtcaa aacgtcgatc ccgtgcttct atgttacttc cacgttttgc
     3481 aatttgatgg accacttcat aggtagagat tcctccacca atgtcttgat tagaataaag
     3541 aatgagcgag acagaaccca gttgcggatc ttcccgttca atcgtgatcc gagccattcc
     3601 attttcacct tttaaccatt tcgcagcatc aaagggggtt ttcgttcgta gtaacaattc
     3661 tgttttgatc gtttcaaatt ctttatcggt caaaggaaaa tcattcagtt ctgcttgatt
     3721 atttgagatg attttttggc gtaaattgac ccaaagatct tcttctgatt ttagatcggg
     3781 acgatacgtc cactgattat gcccttcccc caatacacgg atcaactgtt cttcgacttc
     3841 cgcttcctca cggtgactaa ttttcattta tcttccctcc ctaaacaaac atcttttgta
     3901 agaagccttt tttcgtttcc ttcagcaaat ctaacttacg ttgatgaaga gcgatcgtgt
     3961 cgtcgagttg tttgaagaaa gcgccgattt tttgttgttc ctctttattc ctagtaaaag
     4021 gaaacttgat attagcgaaa ttctcataga ataagtattc tcgtacgctt ccttcagtgt
     4081 tgcgcttgac ctctttgata aatgttggtg acttgataaa ctgaagtatg aactcattat
     4141 ctaagtcctc gctcattttc acaactacat aaagagagct aacaatgacc gtcataccaa
     4201 gattgttaaa tgcaattgat cctacgttta ctcttgctgg attataggcg aattcatttg
     4261 gttcaacgaa tttataattt gttttttcta aatcatccaa cctactacca tcaaactgtt
     4321 ctgtttgaga aattaaacct gctttattac ttaccgaata ggcagggaag tctaaatctt
     4381 tcgtgttctt ttttccagtc ttcttactaa actctttgaa cttacgctgt tcccaatctt
     4441 ccgtaaatcc aggaaaccga atttctggca cttttgctcc gtttttaggg aacatttttt
     4501 gtaagaatcc ttttttcgtt tcctttaata aatctagctt acgttgttga agagcgatag
     4561 tgtcgtccag ttgtttgaag aagttcccaa ttttcttttg ttcttctaat attggaaatt
     4621 gtactatcca ttttttcact tctgacattg gtacgagatt tgtaattgct gaacctggat
     4681 tagctcctgt gagttttctt tgcataaaat ctgcacgaat aaattgaata aaatattctg
     4741 aatctgtgat ttctttattt attctaagtc taatcaaagc ctgattgaat acacccggtt
     4801 ttatttgctt tggtactctt gaaattctcc caattgttcc agcgccactc atgataaaat
     4861 cgcctggttc taatttaaat ttgattaatt cattatattt tttttcagta attttatatc
     4921 ttgtttcgta attatcataa atagcatttt gttgttcata gacaacaaaa ttgctattag
     4981 atacaaagaa ttctttcttt aaggcactcc caaatggtcc cctccttact ccatcttttt
     5041 tatcaagtaa gcattcaaac ttacgctgtt cccaagcttc cgtaaatcct gggaaacgaa
     5101 tttctggttg tatatcatta ctcatgtttg aacacctcca gcgcaccttg taaccacgct
     5161 tcattttcag gtgttgtttg cagggaagag atagcttcta aaagttcttt ttctagcact
     5221 tgctgttctt gtcgtatctt cttgatgtca tttccgacat gaaccatatc aattggttct
     5281 tcttcttcaa acgtatctac atagcgtgga atatttaagt tatagtcatt ttctttgatt
     5341 tcatcaaagt ttgccaaatg agcgtatttc tcgacatctt ttctttcagc ataggtttcg
     5401 aggatttttt gaatgttttc ttccgataat ttattctgat tttttccttt gacaaattct
     5461 cgactagcgt caatgaataa tacgtctcga gtttggcggt tctttttcaa tacaatcacc
     5521 gtcgttggaa tcgatgtccc gaagaacaag ttcgcaggca taccgatcac agcataaata
     5581 ctgccgtctt ctagtaattt ttgacgaatg accccttctg cagcgccacg gaataaaact
     5641 ccgtgtggca agacgatggc catagtccct gtttccttca aatgatagaa accatgaaga
     5701 agaaacgcaa aatctgcttt ggattttggc gctaattttc cataacgatt aaaccgagaa
     5761 tcgtctaaga aggtcgtatc tgctgaccaa ttagccgaat aaggtgggtt cattactact
     5821 gcatcaaatg tgtaaggttc atctgttggc caatccttat tcaacgtatc cccattgcgg
     5881 agattcattt cttcggcatc taccccatgt aaaatcaagt tcatttttgc tagattgtat
     5941 gtcgttgtat ttaattcttg cccatgatat ttaacgttat ctgggtgagt taagtagtta
     6001 cgcacattta acatcaatga acctgaaccc atggttggat caaaaacact aaagaatcgt
     6061 cgttcttttt gatccaacgt cacgatttgt gccatcatat cagaaaccat atgaggcgtg
     6121 taaaattctc cggctttctt ccctgcttct gaagcaaatt gactgatcag aaattcataa
     6181 gcatccccga tcacgtcccc atcgtgacct aaaacttcca cgtcattcaa tttcttaatg
     6241 acttcggtaa tcgtcacatt tcgttgttgc tcatctgttc ctagtttttt tgattggaga
     6301 tccacatcat caaataaccc attaaattga ttgtaggtag atgccaattg cacaaaggct
     6361 ttgtttagat cattcaattg gaacgttgct tgttttgctt gatccgctaa gacgttgaaa
     6421 agatactctg gcgaaatcgc ataccccaaa atatcaacga ttgttgcaat cagatcttct
     6481 tttgattctt catctgaaag taattcgcga tacaacatcg tttgtttgct taccgtatca
     6541 tattcctcta aggattcatc tgctaaaaga accacttgtt ccaacaaacg gtcggataaa
     6601 tatttataga aaatcagtcc caataaataa tttttatatt ctgacgcatc cattttgcta
     6661 cggagattat ctgccgcact aaataatttt tgatttaatt ctgcacccaa aaagatacac
     6721 tcctatctct tatttaaagt tgctatatac cctcttattt tagcatactc ccttttagaa
     6781 aaagcaaaaa aaaaaagaaa gaaacttatt cttgctaata aactacgcga aaggagtcta
     6841 acgttgtttg atataactta gactgatcgt taacttattt tttatatttc tacatagtta
     6901 tctttagaac catttcagat acatatgaaa caattacata tgattttttc ataaaaaaac
     6961 agtactgtct agtagtataa aatatacaaa tttcttaaaa attttttcac taaaatcact
     7021 acctgaaaca gtctaaaaca cttatatatc aacgtttaat gaaactatct ccgtttcatt
     7081 tcagatacaa ataaatatag tcgggctcca aatccgaaaa aaaatacccc cagtagctta
     7141 tcctaagcta ctggagatgt ataagtacgg tcatataaca acggggtagg gtaaataaat
     7201 gaaaaagatg gaagaatcat tattcaataa cttttttaaa tacttcgttg taatcagtta
     7261 cctgtccgtt cttaaatacc acagaataat cttttttccc attttcaagt aaccgaagtg
     7321 gaatatcttt accaactttc tctgtcactg cattactgat acctgttaga ttagctaata
     7381 aatctgataa agattgagca tctgtagaaa tctctgtatc agtatttatc gtgattcctt
     7441 tatcttcatt tacaagtttc caagtaggtg gtatagctgt gtatgtttct acaaatgaat
     7501 taagtttttc attaagtgac ttctctttta tatttccatc taaaaactct gtatatatgg
     7561 cttgagctat actaaaacaa agctggcctt gttctaataa ttttacatca ttagttagta
     7621 aagctgtgtt cacgttatca atcgcttcaa gaagagtatc tttggtgtcc ctaacagctt
     7681 taggtgtgcc ttctggaatt tccctacttg atacctcgtc cattttatct tccataaacc
     7741 ccttaaaatc atatctttct cccaaatcca tagaagtttt tgagaaagct ttcatttctg
     7801 agtctatttc ttcaataata tttaacatgt ctgatacata ttgtttaggc tgattcgttt
     7861 ttaatctata tgtggtaaat atctcaattc ctccaattat caataaaatt gccaaacaaa
     7921 tccataataa ttttttcttt ttcatttttc ctcctataca ctgctgttat aacagtgact
     7981 aatgtaaaga ttttcccagc aatcatcaga ctattattta cagggaatca aaaaaactcc
     8041 ttagtaagct tacaccttta ggagttcctg tttgaacggt atgcataata catttaaatc
     8101 aatttaacat taacacctca gtatatggta tctctacata tacacggtct ttttttggat
     8161 agtactcgac atttatattg atagcacttc cattgtctaa cgtagcttta gcccggtacg
     8221 tgttatcacc attatcatga gtgatcgtca catcatcaca tgtccgattt aagttatact
     8281 gttcttgtaa aatctgagtt accaatggta cagatgactt ctctagtcca gatgaacccg
     8341 tcattcttga aaaaattata cctataatag ccaatacaac gatacctata atgacaaact
     8401 tcttattcat atttacttta ttcaactttt tatctcctat ctccaaaatg attttctctc
     8461 atcagtaact cattgacatc cccaatagta caccaaagat ggctccagct acccctgcta
     8521 tcatcaaaat cgtacccatt tgttcatctt tctctcgata taagtaaccc ataataacag
     8581 caacagcacc aaataccaca ggaataaatg ctaatgatac taccatagaa atccaaccaa
     8641 taatcaaata cagcttccct gtctcttgtc catgtacgat ttgttccttc atttcattaa
     8701 ttgtctgctc agtacttttc tttactgtgt ctgttccggt tgtctcatct gtttcttgta
     8761 atgctccgca aaactggcaa tacttacttt catttgttat ttctttacca cattttctac
     8821 aatacatgtc ttctcctcct aaaatcattc aattgcttat tagctaactg tttactttat
     8881 taaatacatc agaaaacagc tcatttattg gtacacttaa tatctcagaa agcattttca
     8941 tttgataggg tttaggaatc gttctccctg tttgccacga acttacacat tgctgtgtaa
     9001 cattcatttt tttggctaac tcagtttggg aaagtccttt ttcttttctg tatcggctga
     9061 gattacttac ttttttcatg attctcccct cctgttttat tatatacaac aatatgatgt
     9121 atttcaactc ataaaatata taaatacttc aaatgtcatt acaaatacaa caacttgttg
     9181 tactctactg agaagggggg tgtattaatg aaacagaagc aatatgcaaa ggtcattaga
     9241 gaaaagcgaa aagcactcgg gtggacacaa aaagaattag ctaaaaaaat cttctctaca
     9301 caacaggcag tagcaagatg ggaaaattct gtaacagaac ctaacctcga tagcttaaca
     9361 gctctttcta gagccctagg aacccctgta agccattttc tagacaatgt tgacatagat
     9421 tatgaggaag agtttttggc tctctatcgc tctcttagta ctgaagatgc aattcgaaca
     9481 attgactata tgaagctatt aaaaaggcaa gaaaatgaac gcaatcagct attgaaagat
     9541 tgaaaaataa ataacccacc gaactttaac ggtgggtgta ttgagatgaa ataagattaa
     9601 gagctatgga taacctgtct agtttaatat aattgggtct cttctattcc ttactctccg
     9661 tccatcatct cttgttacac ttgtaaattg ataaatagga actaattcaa ctcctgataa
     9721 tatcaattct tttattactt catctatccc tgcccctttc gctagatata ctaaaaaact
     9781 actgcttgct ttcacattgt atagtttctt aatatcctta gaagctcgtt caagagtgaa
     9841 tccttgttta acaaagtagc ctctgttttc tattaaagca tttttcacgc tgttatccct
     9901 gacatttcgt aggcgttcac aaacagtgtt aataagttct ttttctgtca ttagatatgt
     9961 cccttgccac gataagccct gtaaaacttc atgtgcttca tctaaaatca attgtttttc
    10021 cttgctaagt tctgatcggg aattttgagg aaatactctt ttagcctctt tttcgttaaa
    10081 acatatctta acccattcat aagaaaaata ttgatatgta aaatgaaatt tttccagaag
    10141 tggaaggata tcttcattca atttttgaat cacagaagtt gcattaaaaa cgtctaatcg
    10201 atagacattg cttctcttat gtttaaagtt tcctaacgct ttctcttcct ttaacctatt
    10261 taggtattcg agcatcttca aaggaacatc ttcatcatct aattttttta tcaatcctat
    10321 aaaagtcata agtgatagta acttattaca tttatctatg tcataagttt taccatagta
    10381 agaactcatt tttttagcta attgttcccc cgacaaaata caagtcacac tttccttact
    10441 atcatcaaaa aaattaacat cagaaagcaa gacatcatag acacgtcgca tttcctctag
    10501 ataattcctt attgtcctga aaagtttgtc tttcattgat tcaagagtgt caaaaagtac
    10561 ttttgattcc tctttcaatt ttcgaaaatg tgtaggatac aagtctaggt tctctaatag
    10621 ccaattaaat gtttctaccc gactgtcttt ctttaaaatt agcatcacaa ctccaataaa
    10681 attttcactg atatcacaat tactggaatg acaataaaaa atggaatgcc cagttttact
    10741 ggtaaaaata ctagcagagg gattatgatc gttgtgaaac agacatctta agtttttact
    10801 tgacttaagt aatttattca tatcaatggt taacaatctt tcataaatct cattaaaaga
    10861 catgtcggag gaatcaaaca ggcagtcttt aaaccactgt ttcatttctt ctttgtcgtc
    10921 attttttatc aacttaacaa aatcggtttc attgactagt tcatactctc tccctgaatc
    10981 actttgacaa tttttagaac atgtcatggt aaaatcaatc ggaagctcag taatatctaa
    11041 catgttgtct tcattaatta ttatcactgc atctgactta tatcctccaa aaaacattct
    11101 attcgaagca tttacattgt catcacaccc ggggatgttc tttttcaagt attcgtaaac
    11161 agcaaccatt ttaccatagt cagtaattgc ttcttttaat agaaagacaa tcttgtattt
    11221 ttctagattt tcagagtacc gaatactttt ttgtatcgca aacgcagaat tatgaactaa
    11281 attgatagat aaaacctttt ctatgcttaa gtatctacta tcatctttac tcaaatctac
    11341 taccttcccc ttctcatctt taacagtgtt atcgacatcc agaataatta ctctggtttc
    11401 cacaaaactc tccttgtcat tgcctttatt ctttgtcttg cttggaataa atgattgtga
    11461 tgaatttagt atctctacaa actcatctct tgtaacttct ctatagttat ctaaacacct
    11521 atctcttaca tcagtttttt ctttttttgt aactggcttc tctaataatt tttctttatc
    11581 tacataaatt ggaatattaa tcattgatgt ttccatttgt gtttcctcct tataaaattc
    11641 tgttaaagac taaaacatac agataataaa aacaaactct ttattactat atgttttagt
    11701 cttatttgtt tactcaacct ttataccgtt ccatgaaact atcaatatca gattttttaa
    11761 atctaatgac cgtatcaatt tttataacag gtaacccgta ttgagaaaca tattttctaa
    11821 tcgttcctac tgatacacct agatattcac ttgcctgctg atagtccata tactctagag
    11881 tgactccaga aataatgtct tctagcatag gctttagcac tgtaattatc tctttcactt
    11941 gttgttcaac ttgtatagaa acaatgctat caatgatttg tagagacata tttccccctc
    12001 ctttcgtgat tgcttgaaca aattttctaa gaattatctt cgtatttttt gctcaaaata
    12061 aaagtatttt gttattaacc gattaatcaa acaaaaaatg attaccagtt catcgacata
    12121 cacataatac ctcgataaaa aaggggtgtc aatagttttg taaaatttat ttacaacacc
    12181 ccttttttga ggtatactaa ttttaggagg tgtggtcaat atgataaaac gtccaccaat
    12241 aaattattta gaacgaaaaa agatactcgg aacaaaaata aaagctataa gaaagagtaa
    12301 aaaattaaca caaccagcat ttggtcttat gattaacaac ggtcaattaa ttgacaaaaa
    12361 gactatctac gaatgggaga agggaaccta tttaccaata ccagagcgat tatcccgaat
    12421 tgctgatttg ggaaatatga gtatagagga gttagtttgt ggcaatgtag aagaatatat
    12481 tttgggaatt attctttata gagatagcat tgtactagat ggtataacat ttccagataa
    12541 aaacctgttc cagcatcttc gtcaacagtt cccaccagta cactctaatt tagatacatg
    12601 gctggataga tattccaaat tagaaccaga gatgcaagaa tttattgcta acaagacttg
    12661 taataaagtt aaaaatgaaa aaattagtct tttcaatatc ttaaaaatag aagaattatt
    12721 catcaatgct attgtagaag aatttgacaa taacattctt ttcctcacta gcagtataga
    12781 agaactacta gaaagaatgg tagatgaatg gctacctatt caattgaaag acatgtctta
    12841 tcccgaagaa gctgtgagag aaattactga taatataaac aagctagaac aaacgatttc
    12901 atcaattggg aaaaaataca ctaagaaaaa aatgaaggga ggtgatacca tctagtggta
    12961 agtactcctt gtaaactaag aggagatgat ttcatggcaa aaatatcaaa gtacaaaaag
    13021 aaaaacggtc aagtggcgtg gatgtataaa ggacacattg ccaccgatcc acgaactggt
    13081 gaaaaaataa atactacgag aagaggtttt agtagcaaac aagaagctca aaaagattat
    13141 gacgagtaca gacatcaaat attatacggt gttaaaaaga aagcacctga tatgacattt
    13201 gaagacctgt ataatgaatg gataactcat cagcgtacca gtgttaaagc ttcaacaatc
    13261 gcaatctcag taagatacgc aaataatcaa atacttccag catttggtaa gcttaaacta
    13321 tcgaatatct ctgtcccata ttgtcaaaaa gtggtagatg aatggcacag taaatatgaa
    13381 agttacgatt atatgagaaa acagactgca caaattttac gctacggggt tgcaatgcaa
    13441 tatattgaca ataatcctat ggaaaaaaca cttcttccac gaaaaaaaga gtatgagaaa
    13501 aatcgtaaat tttactcaaa agaggagctt aataatttac tggatgcttt taaagatttt
    13561 ggtaacatga aacaatacgc cttcttcaga ttattggcat acacaggtat gagaaagagt
    13621 gaagtactcg ctttacagtg gaaagacata gacacgttta ataaagaact acatgtcaat
    13681 aaaactcttg ctgtagatga atttggtaaa gttataattc aatctccgaa aacaagagct
    13741 tctagacgag ttatctcttt agatactgag actctttcta tcctcaacaa ctggaaatta
    13801 cagcaaaaag aagagtattt aaaacttgga tacaatacta gctctaaaga gcaacatgtt
    13861 tttacaacag ttaaaaacac tctatacatt ccaaacactg ttaatgattg gttaagatat
    13921 attttgaaaa aatataactt gcctcgtatt acacctcatg ggtttagaca tacacatgct
    13981 agtttattat tagaagcagg agaatctgtc aaggtagttc aacaacgatt agggcatgaa
    14041 aatagtaaag tgacattaga catctatgca catattacaa ataatgcacc taagaaaaca
    14101 ggtcaagact ttgctgatat gatggctcat cagtaaaaga gctggtcaaa atctggtcat
    14161 ttctagtata caggcaaaac aaaaaagcta gaacccttat at
//
LOCUS       DAPBAF010000063        13926 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.063, whole genome shotgun sequence.
ACCESSION   DAPBAF010000063 DAPBAF010000000
VERSION     DAPBAF010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13926)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13926)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13926
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.063"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            168..362
                     /locus_tag="RD451_002451"
     CDS             168..362
                     /locus_tag="RD451_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567666.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
     gene            631..930
                     /locus_tag="RD451_002452"
     CDS             631..930
                     /locus_tag="RD451_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567667.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(1027..1461)
                     /locus_tag="RD451_002453"
     CDS             complement(1027..1461)
                     /locus_tag="RD451_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7567668.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1693..2403)
                     /locus_tag="RD451_002454"
     CDS             complement(1693..2403)
                     /locus_tag="RD451_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HDT7567669.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(2393..3253)
                     /locus_tag="RD451_002455"
     CDS             complement(2393..3253)
                     /locus_tag="RD451_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HDT7567670.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(3258..3896)
                     /locus_tag="RD451_002456"
     CDS             complement(3258..3896)
                     /locus_tag="RD451_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HDT7567671.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3911..4210)
                     /locus_tag="RD451_002457"
     CDS             complement(3911..4210)
                     /locus_tag="RD451_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDT7567672.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKGVTVIGIKNVMSVKEISEKFAETKWYQKNK"
     gene            complement(4253..5737)
                     /locus_tag="RD451_002458"
     CDS             complement(4253..5737)
                     /locus_tag="RD451_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HDT7567673.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQALIFMGLILGCYWTVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPDGYFLIVEDYDTYAEKQRV"
     gene            complement(5757..6218)
                     /locus_tag="RD451_002459"
     CDS             complement(5757..6218)
                     /locus_tag="RD451_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDT7567674.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGENEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(6236..7303)
                     /gene="ulaG"
                     /locus_tag="RD451_002460"
     CDS             complement(6236..7303)
                     /gene="ulaG"
                     /locus_tag="RD451_002460"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HDT7567675.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADPKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            7521..8291
                     /locus_tag="RD451_002461"
     CDS             7521..8291
                     /locus_tag="RD451_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDT7567676.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(8564..9391)
                     /locus_tag="RD451_002462"
     CDS             complement(8564..9391)
                     /locus_tag="RD451_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7567677.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
     gene            9959..11194
                     /locus_tag="RD451_002463"
     CDS             9959..11194
                     /locus_tag="RD451_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HDT7567678.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
     gene            complement(12193..12453)
                     /locus_tag="RD451_002464"
     CDS             complement(12193..12453)
                     /locus_tag="RD451_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HDT7567679.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(12480..13781)
                     /locus_tag="RD451_002465"
     CDS             complement(12480..13781)
                     /locus_tag="RD451_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDT7567680.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEEAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNAALLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPIIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
BASE COUNT         4493 a         2839 c         2181 g         4413 t
ORIGIN      
        1 taagaacaat agccttttat tatatatatt attcaaatta gttatatcga gtgaaaaaaa
       61 ctttcaaatt gattcttttt atttatcata aagatataga tacataatca ttttcactta
      121 catatatttg aatattaact aaaaacagca agaaagaaga ggatcaaatg tattatgtag
      181 aagtaaaaac aaaaggcgtc aaaaacaaac aatatgtgaa aggtatcagt aacgaatatc
      241 ctttacttgg ttcatggaaa gaagctgctc ctttttccaa accatgtgcc ataaaaataa
      301 agaacgagct agaaaaagaa ctgacttgtg gtaaagctgt tgtagatatc atcgaaaagt
      361 aaatccaatg tatagaaagg aagatcacac atgaaaagcg acgtacaaat tgctaagatt
      421 atagaattag aagaagaaga cgcagtgttg acaattgaaa aaaaataaat gtttgtatac
      481 catatgatta tttcaatatg tatcctggaa ttggagatct cgtagagcta tatcaagatg
      541 aatcaaatat acttgtcatt catcatgaaa tatagagact tataaaattg tttattttta
      601 taatgtatca gtatagaaag gaaataaaac atggattata ctgttgaatt tgacagtgaa
      661 ctacttaagc aatttccaca agaagaacat ttcatgtata aagaagcaat ttcccacaaa
      721 gtgacagagt atttggagca taattttttt cgtataaagc cagtgcgtac tcgttcggca
      781 aaaggaatat acgagatgaa agtcaaaatt aataaaaaaa attatcgcat agcatttgct
      841 ttaaaaaaaa atcatgtgtt cattttttat attagttcga atttgcaaaa aattgtattt
      901 gataaagagg tgagtaaaaa aataaaatag ctgagcattg gaggatagat tgagtgatac
      961 taagtctatc ctcttgtttt tctaaagaac taagctagaa ttttttcttt tgtacgttat
     1021 tatatgttat ttgtcattac caaaaagcac cttttttctt ctagtatcta tgacataaga
     1081 aataccaccc atttccttta cttgaacaaa tcctactgat tcataaaatt tttttgtttt
     1141 ctcagtatca tctgtcaata attcgatttg gactggtcca taactagtga tcttctccaa
     1201 agcttcattc aaaagcactt tgcctattcc ttggcgctga tacctcggat gaatgaggat
     1261 atcttgaata aatgcgatcg tcgcaaaatc agtgatccaa cgaacgattc cgataatctt
     1321 cccttcccca ttacgcttta tcagagattc agattgttca aatgctctag ctaaccttgc
     1381 agtgtctttt gtgtaattcg tccaaccaac gctcttatat aattcagaaa tctcatcgat
     1441 cataagggaa tcaatattca tttttttctt cctttcttat acaattctcc ctctaataat
     1501 acagttcttt gactatttaa tctatcacat ataactctcc tgtaaagatt ctctcgattc
     1561 cttaaaattc ctctttcctt ttagaatgca tactttttga taaataaaaa ggttgtgata
     1621 aattttcttc acaacctctg tttctctcta tcaagtgtta tcttttaatt ttctaccctt
     1681 accctagcat ctctattgcc cgtagtatgc atactttcca tgtttgcgaa aataatgttt
     1741 atctagtaaa tattgcggga tttcacatat attggggttg atcagctcgt tttctttggc
     1801 catcagacaa atttcatcta agatcaaact gttttctact gctttcatag gtgaatcccc
     1861 ccatgtgaac ggtccatgtc catagacaag tactccaggg acttcgtttg gatctaattt
     1921 tctttcctta aacgtctcga caatcacatt ccctgtatga acttcgtaag cttctcttac
     1981 ttcttctttc gttaattggc gtgtacaagg aaccttacca taaaaagcat cagcatgagt
     2041 cgtgccataa gctggcaaat cgcgtcctgc ttgcgcccac atgacggagt gcgtggaatg
     2101 agtatgagta atagcagtta tatcttcaaa agtttgatac aaaacaacat gtgtggggag
     2161 atctgaagat ggttttaagc tatcttcttc tattatattt cccgacaaat ctgttaccac
     2221 catttgatct gcttgcatgc attcatatct gacaccgctt ggcttaatga cgatgactcc
     2281 tagctcacgg tccacttcac tcacattgcc ccaagtcaat ttgactaatc cgtatcgcgg
     2341 caatgccaga tttgcttcaa ggacacgttg cttcattgct gcaatttttt cttcacaaga
     2401 catcatagcc agcctccttc aatttagaac ttaagtagtc ttttgcctgc tggatttctc
     2461 ttcgaaagtc ttggcttttt tcactccaca tttcaatcag aaatgttcca tcataatcta
     2521 gacgtttcaa atgtcttaat aatccaagaa aatcaacaca accgctacca aaaggaacat
     2581 cacgaaactg gcctgaatat tcttttgtta cagggtaagt atcttttaag tggatagcag
     2641 tgatataatc gatccctttc tcaagttctc gagccggatt attttccggc catgcggaca
     2701 aattgcctag gtctggatat acttgtagaa aaggtgaatg aatctgttct ttgatttcta
     2761 aaaattttga aatggagttc ataaatggat catccatgat ttccacggaa agaatgatgc
     2821 catatttaga agcttccttt acgctttctt ttattccttc gataaagtct tctctggaat
     2881 tcattgattt ctcttcataa taaacatcgt atccagctat ttggattact ttgacgctta
     2941 gattatgcgc caaatggatt gcttttttca ttagttgttt cgctgctttt ttcttttctg
     3001 gatcagcaga accaaacgga aatcgccgat gcgcacttaa acaaatcgaa tggatacgta
     3061 caccggagct gaacatctct tctctcagct cagctatctt ttcttcagac caatctaatc
     3121 gtgctaaccg ctcatccgtc tcatcaatcg acatctcgat aaaatcgaag tccatttctt
     3181 ttacaaggga aaaacgttct ttccatgaaa tatctttggg taacgctttt tcataaatcc
     3241 caatttgagc catttcctta cccccagata cgaatgatct catctttgaa gttttgtgcg
     3301 gccttcatcg gatcatttgc tgctgtaata ccacgaccag tgataaaggt atacacatcg
     3361 atcccttcaa ataagtgtaa tgtgtgtgga tttaatccac cagttacaga aacattaaag
     3421 cctagttcaa tcagtttttt gatcttcgat aaatcttttt caccccaagt ttcaccagat
     3481 aacagcgcat cacggctttg atggtagatt acctgccgga taccgatgtt atgccaatcc
     3541 atggcttgtt caaaagtcca attgccgtag agttctactt gcaattcacc tatttctttt
     3601 tgtgctgcct ccatagttgg aatcgttgca caacaaatga ctgtcatcca gtctgctcct
     3661 gcttttgcaa cattactcgc cactgttcct ccagcgtctg cacatttcgt atcagcgact
     3721 agttttttat ctgggaacat actgcgaata cagcgaatcg ctttttgtcc ttcctgtaag
     3781 caaagaattg tgcccacttc aataatatct actacatcac caactttcat aacatctcct
     3841 aatgcatgtt ctaagtcatt gtgatctaac gcaatttgca aattcggcct gctcatctta
     3901 gttccttcct ttacttgttt ttttggtacc actttgtttc agcaaatttt tcactgattt
     3961 ctttgactga catcacattt ttgataccga taactgtaac tccttttttc tctgcctgag
     4021 taaacatatt caaaaaattg actggcgtaa aaactacatc gtattggcca gctgaacttt
     4081 ttccctctga aatggcacaa tgatggattt tggtaattgg tacgtttagt tctttcattg
     4141 ctttttccac acttctcatc atcatcaagc ttgttcctga tccatttgca cacgatacta
     4201 aaattctcat cttaatccct ccattatgag tgttgtctaa tcagattttc ttttatactc
     4261 tctgcttttc tgcatatgtg tcatagtctt ctacaatcaa aaaataacca tcaggatttt
     4321 tccgatattg taactgcgga atagccaata aaccaatgac aactacggca attccagcat
     4381 aacctaggac tttcatgatt actgtaaaca atggccaagc tgttgcccag tcgaacatcc
     4441 cgatataacc accgtatgtt gacatcccaa tccatgtagc gaataatgct gaaccgccta
     4501 cttgtatgat tcctgaaaga aacgggaaca ggcaagcggc tttgaatcca cctcggttat
     4561 tggcataaac tgctataacg gcattatcaa agaacaacgg aatgaaaccg gctatgacga
     4621 tcgttggtga tttcaataaa atcagtaaac caatcatcaa aaactgtccc aaagcaccaa
     4681 acaagaaccc aatcgttacc gcatttggcg aaccaaagcc aaaagtagca gctacgtcaa
     4741 ttcctggaac agctcctggt aaaatcgtgt ttgagattcc ttggaaagat tgagttagtt
     4801 catcgacgaa tgtccgaaca cctaattgca agatcgccag atataccgca aaatttaaag
     4861 aagtcgtcat aatgtagaat aagaaactct gcccttcttg catgaattgc gcttgaatca
     4921 aataatcttt gcctagtaca atcagaatga tcccaaagaa aaatagcatg agtaacgaag
     4981 tagcaaccat attctcattg aaaatcgaca agaatcctgg taatttgata tcttcaattt
     5041 ttttgtcttg cttgattgat ctatttttct tttcatcccg ctttttcatc cactcagcta
     5101 attttgcaaa tataaagatt ccgaacattt gctgatgtgc cactgcaaat ccggcacctt
     5161 ctgtcaattc ctgcgtgatt cctactgtta agttagaagc tactgtccaa taacaaccta
     5221 aaatcagtcc cataaaaatc aatgcttgta tcctacctag atcaggaaag caaaacagta
     5281 aaatccaaaa agcggtagct gcttgttgaa cctgaacgtt tccggtagtg aaaacggaac
     5341 gcagtttcgt atatttctga aaacggacta ataagatatt taaaacaaat gcaatcagta
     5401 ataaaatcat cacatctcca aaggtacggc caaatgtctc cattaatcca gcatccacag
     5461 cattttgtcc aaaataagga tctgtaacca tggcatccaa attgaaccgt tcctttagtc
     5521 caaccaagat tggccgaaaa ttattgacca aaccaccaga gccaacagtc aaaataaagt
     5581 aaccgaccgt tgcctttaag aatccagcga tgcattcatg aagcgggcgt ttcagcaaaa
     5641 tatagcctaa taacacgata aaaccaatca ggtatgctgg ctgcgtcaag atatttgttg
     5701 caaaatacgt ccaaatgctt aacaaaaatt cccccatctt ttttctcctc tatcaattaa
     5761 ttatattctg ccatcacaac ttggtaatca tcgatggagt tcgtagagat gagacgctca
     5821 accaatccat ctgtcattaa taattcggat aatttttgga tattttctag atgttcttct
     5881 ggatcttttg ctgcgagtgt aaaaaacaaa ctagccgttt tctcctcatt ctccccttca
     5941 ctttcaaaac ggattggctg tttcaacttg gtaaatgaaa tagctgttcc aaaaacacca
     6001 tcactttttt ctgaagaatg cggcattgct acttgaggtg cgatcacaat ataaggaccg
     6061 tatttttcta cacaatggat gatctcctcc acatacgttt catcaataat ttccttatcg
     6121 atcaatacaa gacagctttc ggcgatagct tcacgccaat ccgtgatttc tttatctggg
     6181 taatgaatca attgatggtc aaaaaagtat ttcagcaaga aactcccctt ctttcttata
     6241 aaaacgacgg aaacggtgta tcattttcaa tcgagaagac atcttcaaat cctcgataaa
     6301 aattaaactc aagatcatct ttgtttgtcg gatagatgaa tttcccgcct acttgccaga
     6361 tataaggttt aaatccatac ttcaggcgat cctttttgaa tttccaaatt tcagtgatct
     6421 cttttggatc agccataaaa ttagaccaaa tatcgtagtg gacaggaatc actacttttg
     6481 cattcaatga ctccgccatg cgcagcatat caacagaagt aactttgtct gttatccctc
     6541 gtgggttttc accataggcc cctaaacaga catcgatttt gtgttcatta ccatgtttgg
     6601 caaataaatt ggagtaatgt gaatctcctg catgataaag attccctcct gatgtttcga
     6661 ataaatagtt tactgcaatt tgatccatct cctgaggcat ttttcctttt aatacctctt
     6721 ctggatcttc acaagtgacc aacgctgtcc gatcaaacgc ttctaaagct actacattga
     6781 tgtctttgat tttgactgca tcacctggct ttactgtaat cgttttttct tcaggaattc
     6841 cccatttttg ccacgtgcga accacttctt ttggcccaat gaatgttgct tcaggacaat
     6901 tttgatgaac tgctgcggct gtatggatat ctagatgatc ggaatggata tgtgtaacga
     6961 ttaaagcgtc tacatttttt atcgcaaaag gatcgattac gaaaggctga gtacgtaaat
     7021 taggctgcat attttgaacg ccactcatac gcatcatctg atggcctttt ttcatcatgc
     7081 cattcccatg actacgtttt cccgtcccac accatagatc acataaaata ttcgttcctt
     7141 catgactttt cagccaaatt cccgtacagc ccagccacca catagcaaaa gttccaggat
     7201 ccactacttc tgtttcgatt tcttcattca agtatgtgcc ccactcagga aatgtttcta
     7261 ctaaccactt ttcttttgtt acttcattga cagttttact catttgcttg ctccccccat
     7321 atcgttgttc caacttacaa gtaaatatta atgtgtatca gcatccatga aaaccctttt
     7381 atatgaccgt ttgtttttta tatgattttc tttcagtaat caatgattgt ttcagtataa
     7441 taaagacaga tatgaatgtt taaatgaaca actagtcaaa taaatccatg gatcaagatg
     7501 tccctcagga ggcaaaagtc atgaaaaact cacttgtcaa tattgaaaaa cgtcaaaaag
     7561 aaattttgga actgcttcag cagactgaac aactatcaac tttcgaatta gctgaatccc
     7621 ttgatgtatc tattagtacg atacgaagag atttaaattt attagaagaa aaaaacgaga
     7681 tcatacgcaa ttacggttat tgttcttata attacaaaaa ccagactgat tttgatcaat
     7741 ctggtcctga aaggattaaa caagcgattg ccagagaagc tagtaaatac attaacgatt
     7801 atgatacgct gtttatcaat tctagctcga ctgcgttgaa aacactggat tttcttcaat
     7861 ctaaccattt gacagtcatt acaaacaacg tgaaaatcaa ttactctccg cacaaagata
     7921 attgtagtta tattttaact ggtggagaga tgcgctttcc aaaagaagca ctagtgggcg
     7981 acatcgcatt aaatacgatt tcttcagtca atgcagacat ttgtatcatt ggctgtagcg
     8041 gagtcgatgt agtacatggg gtcacaacaa agatattaaa tgaatcaacg atcaacgaaa
     8101 tgatggtcaa caagacaatc aaatgtaaga ttttagtcgc tgatcatcga aaaatcggac
     8161 tgacatcaaa gttcaagatt gctgatattt cagtctttga ttatttgatc actgataaat
     8221 tttgttctga aaaagtatta gaggagatca gaaatacggg gataaaaacc attcaagtag
     8281 attcatttta agaaccagga cgtaaatatg taaataggat tatcaaaaaa atgaataaca
     8341 aatttatcga taaatgaaaa acacgctacg ctcaaattga taaaggaatc ccaagatgta
     8401 tccatccaat cgataccatc ataatctatt gcttctttta taaccgttat atgttgccta
     8461 aataggaatc aaacaatatc gaaaaaagga ggtatgacaa aagtcacacc tccttttttc
     8521 gaataaacgg tattcaaatc agaacactga tttcacaacc actttatttc aggtcgtttt
     8581 caatcacctt taccgcgtaa tcatttccgt tgaaacgcgc tatttttttt gcgtccatat
     8641 atctttctaa ataatcatct tctcctaatt gcttatggca agaagcaatt tcataaagca
     8701 agtattccaa tgcataagtc gatttatgtt tcttattata ctcaataccc ttctcacata
     8761 attggattgc tttatcataa tcctcgattt tacggtaata ggtggcgata tcataatata
     8821 caatgcagac catcagatta tcaaaatcag tctcactcaa tattttaagt gtacgctcca
     8881 cataaacttt cgcaaaatct aattctcctt ttgacaagta gatcattgcc acgtttgcag
     8941 ctgcttgtaa gtgatggata tctgtttcgg tcgtttgttc caacacttga ttaaaataaa
     9001 ataatgctgc atctggtttt ttcgcataaa gatgatcaag cagtccttga taaaataaaa
     9061 tttgatttaa aagatcagaa ttacttactt tttcctgatc gatcgtttgt aaaattttat
     9121 aagattcttg gtattttgat acagaattca atgattgaat ctcatttatt tttttcctga
     9181 ttttgtcttc ttctgtttct actaatatat cggagatctc gacattcagc tttttgcaaa
     9241 gcgcacttaa gatattgatg cctggcgaca tattcttgtt ttcgatattg ctgacagttg
     9301 cttgttcaca aatgccttct gctaattgta cttgtgttaa cccctttttc tttcggtatt
     9361 cttttagtaa tgctccatct actttaatca aaacaatttc cttcccttta aaaaattatt
     9421 tctcctttat atcatacaca aaaaaaagtt ctaaacaacc aaaaatgttt agaacagaat
     9481 aaaaatttta attttaaaat aatattcaaa ttaaacaact ggcgtatctg ctccttgatt
     9541 tctttttgtg ttatctgaat aattatcgtt tacagttata acacatagtg aaaattgtca
     9601 tggcgagaaa gtctaagaat atttttaaac ataactattt ctttcttacg tgtgtataat
     9661 gacgacagca cacctatcaa ttaatataat tattttattt ttttatgttc tcatgtttat
     9721 ttttaatgac acaacttctc gtatttatct ggcacaacat ataaatcgat caaaaaattg
     9781 ttgcgtgttt ttttgaaaat tggagtttca acttgattac aaaatttaaa tttagaagtt
     9841 gtgaaaacag cgagagacag tttaatattc aaaatataca taggctactc gaacgctgtg
     9901 ttttttagta tactagtaag aaacgaaggg atagactcat tccaataagg aggatttcat
     9961 gaagacaatt ctttttgctc ctgcagtatt caatttagct gagacaacac gaatgattga
    10021 ggttgccaaa gctatgaaag accgttatta ctgtgtattc tttggctttt ctaaaacttt
    10081 tgctcctttg atcacagaaa gtggctttga gtatcattta ctagcgccga tccttacgaa
    10141 aaaacaagaa gaacaaatca taaaatttga ccagttgcgt acacttaaaa acccttttac
    10201 caaagaaatg gttgcctctc gtatcactag tgaacagagt ctgattgcta agtttgagcc
    10261 tcgactgatt gtgacaggtt cgaatgtgac aattttttta tcggcccgca ataaaaagat
    10321 tcctttagta tatgttaaac cctatgcttt gagtgaacct ttttttcaat cagagcatgc
    10381 gctgatgccc cacgagttac gtttcttcgg ccctttaagc aatccccttt ggcactggac
    10441 aaaaaagcgt atagtaaata cccgatggat ccccaatgcc ttcaaacacg ctgcacaaaa
    10501 agaaatgctt cctttaccaa aaacaagttt acaaatgatg gatgctgatc taaatctcat
    10561 cacaacgcct aaactatttt tggaagaaga acagctgccg gaaaattatc gaatcgttgg
    10621 tccaattttt gctaagctca gtacttcctt gcctgaagaa gtgctaactt ttatacagcg
    10681 aaagcaacaa gaaagaaaac gtattatcta tttcgcaatg ggtagttcag gcaatccgcg
    10741 tatgttacgc aaaattttgt tcttcttaca aaaacaaccg gatctagcgg ttattgcacc
    10801 tattgactat ctgcttgatg acattcaatc tgactcagaa gatcttttaa taacagaata
    10861 tctgtctagt catcttttgc atgaattcat tgatttttct tttatccacg gcggggaagg
    10921 gaccgtccaa actgcctgtg aatccggcaa accgtttatc ggtgtgggga tgcaatttga
    10981 gcaaagctgt aatattgact attgtgtaaa atacggaaac gcaatcgccc tcacaaaacc
    11041 agtgactgaa agaaaactgc agattgctct gcgcgaagtt tcttcaccca agattcgtca
    11101 gcaggcacgc acgctgcaag ccgtttttcc aataaatggt ccacaacaag caattcaaga
    11161 aatcgaaacc ttcctgagca accacccaat atagtttcaa gtagaaaaag cttttttaat
    11221 agagactcat cagtaatttc gctattcgag acccagacag tgaaaataca aaaaaagtaa
    11281 atagtggatt gaaaagttag agttacttaa attacggtgt ctaaaaaaca caaaatcatc
    11341 cttaaaataa aagatctgac gctatccaaa tgagcatagg tagcgtctgc catttattct
    11401 tagtcaaatt ctttgacacc tttctctggt tggatcatct caacgtttct tcaaaagaaa
    11461 gaccataata attaggcaaa tacattttct taaaatgtgt catatagatc tagaagcatc
    11521 gctttgtaga gatttgtgcc gctagtcccc tcaacaatta ctaaatcaaa tgtaggattt
    11581 accactttat ctttgataat caacctccct cttctgttga gacaatgatc tcgcaatccg
    11641 atgcatactc ctatataaac tgccagcaat ccccacatat tgagtagatc atgtcagaat
    11701 gttctatgtc gtcagcaacg atacactaaa agtcacgttc accatgactg attgctattc
    11761 ccagcacaat tatttctata cacgtttcat gatttgaata aacactcaca tcatacatat
    11821 taccattcat acaccatact gcagccccta ctatatggtt gtaagctccc aaatctatat
    11881 ttgacttgat cactttggta gtagatctac taattctaaa tccattgctg ataaaatttc
    11941 cattttttcc tccttctttc tgccaaaaca gttaaaacaa taataatctt tatgtaaaaa
    12001 agggctgtga caaaagcctt gtcacagtcc catattccga ataaacggtg gtcaaaagct
    12061 tgcatctgcg gtaataagtt caaccaaacg aaaaataagc caacatttca caaaaattta
    12121 agaagcaatt ttcgtaaatt tcttcttatt tcttgaagct aaccacttct gttacaacca
    12181 cttttagaac atttaaagct tcgatgtgac aaaccatcta tgctgctcga tcataaaatt
    12241 gatagcaaaa attccacaaa gtacatatgt cccccatgaa aacaaaacat tcatatgcgg
    12301 tacaatgatc tttggaagaa tcacgatcaa aaatgatgcc agtgcccaaa tccatcgatt
    12361 gatttgaata tgatatgtag ctagcatatt caatataagg tgactagccg ttaataaaaa
    12421 gataaaaaca aaaaataaaa tcaaccaata cattgtttcc caccttctaa aaaccaaact
    12481 tagacagtct ggacttcgtt ttctccacga ctttgttcat ctgacagcat ctttttatca
    12541 taagctttta caaatggata atagataata aatgctatca atgtgttgat catgatcaag
    12601 ataacaacac gccagtcatt tcctgctgaa agataaccgc cgattggagc tggtaatgtc
    12661 catgttggca aaacagtaaa tctattgacc atttctaatt tgactgcaaa ataactgata
    12721 atagtcaaaa ctaaaggaac taagttgaac gggatgaaca tgtaaggatt caacatcata
    12781 ggagctccaa aaattatggg ctcattgata ttgaagatac caggaataat agaaaaacga
    12841 ccaacctctt tcaagaattt tgatttacag aagaatataa acaaaacaga taccacgatc
    12901 gttgctcctg caccaccaat tgttaccgtc cattgataaa actgttcagg agcgatatag
    12961 ggtaattggg tggcagctgt accatctgcc aatgcctttg cattctcatc caacatgatc
    13021 agccacattg gacgaacaac agcccctaca atactcatgc catggatacc aaatgaccac
    13081 aacaaatgga tcaaaaacat tggtagtaaa acaccaagca aattattccc taaaatattg
    13141 gttaaaggct cgaataacga taataaggca gcgtttacat caaagcccgc gacgcttcga
    13201 atcagccaag taattgttaa aatgactgca cctggaatca atgcctcaaa actacgggca
    13261 acagcaggtg gcacttgttc tggcattttg atagtaatat ttcgattttt aaagaaacga
    13321 tatacttcca ctgcaaaaat catagataag atccccgcaa acatcccaga tgctcccaaa
    13381 gaactcatag gtaagaccca gccaagaggt gcctcttcag gagttaaaac gtttacagga
    13441 acttgtaaca taaagaacgt tcctaaagat aatataccac ctgtcacact atctaatcca
    13501 tatgatttag ctagatccga acccataaca aaagttgcat aaatagccat caatcccatc
    13561 gtcatcctaa agggtaaaac aatcgttgcc gaataagggg caataaattc attccatcca
    13621 ggaaacggta aattgataaa gaccataaaa aatgtcccaa tcaaaatcaa tgacaatgtt
    13681 gaaacaaccc cattacgaat tgctaataaa tgacgctgtg taccaatttt tgccattggt
    13741 gggacaagtt tctcttcgac ccatttcatc agcttttcca ctaaaaccac tccttttcaa
    13801 taaaatatga accattcatt gcatgacaac gcaaagaatg ttcataacta attatataat
    13861 taagaaattt tatttcaata tattctctta aataatcaaa tttattttta agaatcctga
    13921 aaataa
//
LOCUS       DAPBAF010000064        13812 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.064, whole genome shotgun sequence.
ACCESSION   DAPBAF010000064 DAPBAF010000000
VERSION     DAPBAF010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13812)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13812)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13812
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.064"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(223..1425)
                     /locus_tag="RD451_002466"
     CDS             complement(223..1425)
                     /locus_tag="RD451_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDT7567681.1"
                     /translation="MKTKYPCVYQDKNGRFSYLVELGTDQVTGKRIQKKGTKDSLGKR
                     FSSAREAHKEVMRIKNEYMVVNGFANYDLTYKEFMEQSYVPHYKASVQKSTWSSRECG
                     LIQITEFFGDKKLREINVRDCENYRIWLLNDSGYSQAYSSLMYGMFRKSLDYAVTLQF
                     LNENISKRTKAIPKGKSIVPYWTKEEFEEVLAKIYKDDFYEHMCFLMIWLYYMTGVRV
                     SEGLALNWNDVDFKRKKLRVHHTLEMTNQKDFIRKPYTKTESGLRIISLDDDTIEVLK
                     KWKVIQKNHGVEQFILSYTDLPLYRSTVQRIIQRYAKLAKVPLIQGKGLRHSHVSYLI
                     NEFNADILVVSQRLGHSSPEITLKHYAHLWSRNDEGIAEQMTGNIKFTCATKSKVANF
                     NGNQAVKI"
     gene            complement(1428..1622)
                     /locus_tag="RD451_002467"
     CDS             complement(1428..1622)
                     /locus_tag="RD451_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HDT7567682.1"
                     /translation="MKNTICRKDLEALGFKTHQATTIIRQAKTRMVNQGYPYYNNKRV
                     GVVPRQVIEEIIGVPLSQEE"
     gene            complement(1669..2517)
                     /locus_tag="RD451_002468"
     CDS             complement(1669..2517)
                     /locus_tag="RD451_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rep protein"
                     /protein_id="HDT7567683.1"
                     /translation="MQAYNQKIIETPTYIEIYDYEAIITPKRKTIENEVNLERKQKLA
                     WIYENDITLEKRKNYDELSAQGQYDSLKRKQKHYQSMRFEIARLVDTNFDNQTKFLTL
                     TFKENIQDIEYANNEFKKFIKRLNYDLYKTKKANLKYLATWEKQQRGAIHYHIILFDF
                     PFISFNRLTTIWGQGFVKINKIDVDSIENRGRYISKYFDKELELKEHKKKAFFKSRNL
                     KLPTVTKKMVKKPYDSTNQDILYTSEYIVRRPFFYNALALNELGSPEQVMDFQESTVH
                     YTKIKK"
     gene            complement(2722..3072)
                     /locus_tag="RD451_002469"
     CDS             complement(2722..3072)
                     /locus_tag="RD451_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002401157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567684.1"
                     /translation="MPIKITDLSLPKETLEKEYQVVNVTRWQKEGEILGWSYECILPK
                     LRYEKISVKVKSEHPVITPEELTQQGLAIITFTNLVIVPWGRSNGQFVSYGLSATADT
                     ATLIPRKQGTTTQN"
     gene            3667..4113
                     /locus_tag="RD451_002470"
     CDS             3667..4113
                     /locus_tag="RD451_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HDT7567685.1"
                     /translation="MKDYVVQITKEVLEESKTLNKLSSKAKEEAVTILSSGIIDYIEM
                     SGEIKYGEKDRIAKMVKESIKTFDVKQDLTFNDSYLIGKLINILGTDEDTELFLSSLS
                     MIFTDKHFSTRFGGEELVEIFQSMRPALIKLYREKTPDEFYDWFEK"
     gene            4737..5729
                     /locus_tag="RD451_002471"
     CDS             4737..5729
                     /locus_tag="RD451_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDT7567686.1"
                     /translation="MYWEEIELEKTLGPGGEIRAVQRDKKNISKWEKLKKQLRRDKWM
                     YLLLLPGIIMTFIFKYVPMYGAVIAFKDYNPMLGILESPWVGLDHFREFISSPNFTLL
                     LSNTLKISIYGLLLGFFPPIILALSLNQIINKKIKQKIQLILYAPNFISVVIIVGMLF
                     LFLSANGPINGLVEKVTGQPIMFMSNPAYFRTIYILSGIWQGIGWSSILYTATLAGVS
                     TDLYEAANIDGANILQKIWHIDLPALRPVMVISFILAAGGIMNVGYEKAYLMQTSMNI
                     PASEIISTYVYKVGLQSGDYAYSAAVGLFNMIINVVLLLIVNNITKRLNDGQGL"
     gene            5745..6629
                     /locus_tag="RD451_002472"
     CDS             5745..6629
                     /locus_tag="RD451_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016608569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDT7567687.1"
                     /translation="MNSALSKIDRQILWLNRVIVTFLVVITIVPLIYVLVASFMDPAT
                     LINKGISFNPKDWTIQGYQRVFADDSILRGFVNSLFYSFSFSLLTVFITMITAYPLSR
                     PNLAGKKIIMTFFVITMFVGGGLIPTYLLVKNLGMLDSVWAIIVPGAINVWNIILART
                     YFSALPKELSEAATIDGANDLQILFKVMLPLAKPIMFVLFLYAFVGQWNSYFDAMIYI
                     KDPDLQPLQLVLRNILIQNQPSQDMVGANTAMAEMKQIAELIKYATIVISSLPLIIMY
                     PFFQKYFDKGVLVGSVKG"
     gene            6678..8285
                     /locus_tag="RD451_002473"
     CDS             6678..8285
                     /locus_tag="RD451_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDT7567688.1"
                     /translation="MKAKWMLPIVFTSVLILGACGGSKEKSKSSPDYELENVSFPLKE
                     KVSLKMMSQSAPLAPNDPNDKLIFQRLEEETNLHIDWTNYSSDFAEKRNLDIASGDLP
                     DAIFNAAAGDYDLLNWAESGVIVPIEDLIEDYMPNLKKIFDENPEYRQMSTAPDGHIY
                     SMPWIEELGEGKESIHTVNGMAWINKEWLDNLGLEMPQTTDQLMTVLEAFKTQDPNGN
                     GEADEIPFSFINNGGNEDLKFLMGAFGLGDNDDHLVVDNDGQVQFTANKEGYKEAIKY
                     FNEMNNKGLIDKEAFEQDWNTYVAKGKEHKYGVYFTWDKANITGADDSYDVLPVLAGP
                     DGTKHVTRTNGMGFSRDRFVITSANKNLELTARWIDKMYEPLQSVQNNWGTYGDEAQA
                     NIFELKDGMLKHLPLEGTAPGELRQKTEAGGPLAVLDSYYGTVTTMPDDAKWRLDLMH
                     DTYLPYITEDNIYPRVFLEKEETDRLAKIETDMWDYIYRKRAEWITGGKIDEEWEEYL
                     AELERVGLEEWIQIKQTGYDNFLKGAQ"
     gene            8286..9770
                     /locus_tag="RD451_002474"
     CDS             8286..9770
                     /locus_tag="RD451_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016621147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HDT7567689.1"
                     /translation="MLVEETAILDKANRFIEMMRGKVNPQYRQNYHFSAPIGWINDPN
                     GFIYYKGHYHLFYQYYPYDSRWGPMHWGHARSSDLVHWEDLPVALAPDQPYDSGGCFS
                     GSAIERDGKLYLFYTGCQEIDGISHQHQCLAVSEDGIHFSKYSGNPVVAEKQLGENGL
                     IQEFRDPKVIVHNDGYYMVVATKSTQSTGRIVMFQSSDLYTWHFYSVLLEGTSEQGIM
                     WECPDLFHLDGRDVLIMSPIQIKKNGLEYHNISSTMACIGEVNWETGQMIVDNFHEMD
                     FGMDFYAPQTTRDPNGGRVMIAWMQMWDRTLPTHELGHLWAGSMSLPRELRVKKNRLV
                     QKPISTVYSHLVYQQGSENIAVTDTSVVFRNALSDSSYLHLVADLEKAEVFTIELLRS
                     KTDCLKLAYDTATQVFELDRQKLGRELTGAEEDPLNVRKVEVPLIDNQLVLEIFRDTS
                     SIEVFINGLEVMTATFYELEKARDILFHSIGESRIQAFETASVK"
     gene            9947..10939
                     /locus_tag="RD451_002475"
     CDS             9947..10939
                     /locus_tag="RD451_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005230454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDT7567690.1"
                     /translation="MKATMKDVAKLAGVGVGTVSRVLNNGSVKASTREKVEAAMTELN
                     YQPDFYARGLKMKHTNTVALILPTVWHPFFGEFAYHVETALERQNYKLYLCNSSGNSE
                     KEQEYIQMVSQNKVDGIIGITYSDIDEYISSNLPFVSIDRYFTEEVIYVTADNAAGGR
                     LAANELYRRGCQNVAYIGGYQETPNETKSRRKYFEIECRQLGISYKALDMLEPLDHLS
                     ERVTNFLLENPDIDGIFTINDPMALAVIDMLEKIGKNVPEDVQVIGFDGQKMTEGDPY
                     LVSTIAQPTKQMAEVAVAKLIAVINGETVEKRTVLPIEFGEGDTTKPLVRNDFA"
     gene            10991..11860
                     /locus_tag="RD451_002476"
     CDS             10991..11860
                     /locus_tag="RD451_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HDT7567691.1"
                     /translation="MLYGGIEAGGTKFVCGIGNEQLQVIERKSFPTTTPEETMEQVFD
                     FFDKYKGNIASIGVGAFGPIDIQIESRTYGYITNTPKLAWQNYHFVGALENALSVPIY
                     WTTDVNAACYGEYMAGYGKGKNSVLYYTVGTGVGGGAVVDGKIVAGFSHPEMGHMLLQ
                     RHNEDQFEGICPFHHDCLEGLASGPAIEKRFGRKAQTISFDHPYWTIEADYLAQCVYN
                     TTLLYAPEVIILGGGVMKQPQLLELIRQSFKEKMGSYVDTPTLEEYLLTPRLADNAGL
                     IGCLALAIKKLNH"
     gene            complement(12280..13773)
                     /gene="guaA"
                     /locus_tag="RD451_002477"
     CDS             complement(12280..13773)
                     /gene="guaA"
                     /locus_tag="RD451_002477"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HDT7567692.1"
                     /translation="MITRRIREFGVFSELMSHRITAEEVKAMNPKGIILSGGPNSVYD
                     EKAFGIDEKIFDLGIPVLGICYGMQLITYKLGGKVKPAKNREYGKAELEITSAEAALF
                     QNTPEKQTVWMSHGDLVTQAPTDFDVVATSKDCPIASIQNAERKMYGIQFHAEVRHSE
                     YGNDLLRHFTLDVCQCTGDWTMDNFIDMEIAKIREQVGDKKVLLGLSGGVDSSVVGVL
                     LQKAIGDQLTCIFVDHVLLRKGEAEQVMESLGGKFGLNIIKVDAKERFLSKLAGVSDP
                     EEKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQGTLYTDVIESGTETAQTIKSHHNVG
                     GLPEDMQFKLIEPLNTLFKDEVRELGTQLGMPDSIVWRQPFPGPGLGIRVLGELTEEK
                     LEIVRESDAILREEIANAGLDRDIWQYFTVLPGIRSVGVMGDGRTYDYTVGIRAVTSI
                     DGMTADFARIPWEVLQKISVRIVNEVAHVNRIVYDITSKPPATVEWE"
BASE COUNT         4233 a         2337 c         2851 g         4391 t
ORIGIN      
        1 aaacctccag acttcttgat agctcaagta tatcttgagg tgcatttgtt agtaaggtac
       61 tgttctatgg ggcgcttacg ttgaaaaacg ttgatttatc ggcattcccc atccatatta
      121 tatttacgtc ttattcccac tcaatatgag tagcctcgta aagaagctat tatatcagtg
      181 ctttttcagc ctattcctca ttttggtagg gaaatggtag ggttagattt ttactgcttg
      241 atttccatta aagtttgcaa ctttagattt tgttgcacag gtaaatttaa tgtttcctgt
      301 catttgttct gcaattcctt catcattacg gctccataga tgagcgtagt gctttaaagt
      361 gatttcaggg ctagaatggc ctaaccgttg cgacacgacc agaatgtctg cgttaaactc
      421 attgattagg tagctaacat gagaatgacg taatcctttt ccttgtatta ggggtacctt
      481 agctagtttg gcataacgct gaataattcg ttgaacagtt gaacgataga gtgggaggtc
      541 agtgtagcta agaataaatt gttctacacc atgatttttt tgaataactt tccacttttt
      601 tagcacttca attgtatcat cgtccagaga aatgatccgc aagccgcttt cagtttttgt
      661 gtaaggtttc cgaataaaat ctttttgatt tgtcatttcc aaggtgtgat gaaccctcaa
      721 ctttttacgt ttgaagtcca cgtcattcca attaagtgct aatccttcgc ttacacgaac
      781 accagtcatg taatatagcc agatcattaa aaaacacata tgttcgtaga aatcatcttt
      841 ataaattttt gccaaaactt cttcaaattc ttcttttgtc cagtaaggaa cgattgattt
      901 tccttttgga attgcttttg ttcttttgga aatattctca ttcagaaatt gcagggtgac
      961 cgcatagtct aatgatttac gaaacatacc gtacataagt gaactgtatg cttgtgagta
     1021 tccgctatcg ttcaataacc aaattcgata attttcacaa tctcgcacat tgatttcacg
     1081 aagcttctta tcaccgaaaa attcagtaat ctgaatcaat ccacactcac gagaactcca
     1141 agtacttttt tgtacgctag ctttgtagtg tggaacgtaa gactgctcca taaattcttt
     1201 gtaagttaaa tcataattcg caaatccatt tacaaccatg tattcatttt ttatacgcat
     1261 gacttctttg tgtgcttcac gagctgatga gaatcgtttt cctagagaat cttttgttcc
     1321 tttcttctgg atcctctttc cagtcacttg atctgttcct aactcaacta gataagaaaa
     1381 gcgaccattt ttatcttgat acacacaagg gtattttgtt ttcatagtta ttcctcctgt
     1441 gaaagaggaa cacctataat ttcttcaatt acttgtcggg gtactacccc aactctttta
     1501 ttattataat atggatatcc ctgatttacc attcttgttt ttgcttgtcg gattattgtg
     1561 gtagcttgat gtgttttaaa tcctagagcc tctaaatctt ttcgacaaat tgtatttttc
     1621 attgtataaa ctcactttca aagaaaacac tatcattggg taatagtgtt atttctttat
     1681 ttttgtataa tgaacggtac tttcttgaaa atccatcact tgttcaggac ttcccaactc
     1741 atttaaagct aaagcattgt aaaaaaatgg acgtctaact atatattcgc ttgtatatag
     1801 tatatcttga ttcgtggaat catagggttt ctttaccatc tttttggtga cagttggtag
     1861 tttgagattc cgggacttga aaaaagcttt tttcttatgc tctttcaatt ccagctcttt
     1921 atcgaaatat ttgctgatat agcgcccgcg attttcgata ctgtctacat cgatcttgtt
     1981 gatcttaacg aaaccctgac cccaaatcgt agttaaccgg ttaaatgaga taaaggggaa
     2041 atcaaacaag ataatatggt agtggattgc accgcgttgc tgcttttccc acgtggcgag
     2101 atactttaaa tttgcttttt tagttttata gaggtcataa ttcagtcgtt tgataaattt
     2161 tttaaattca ttatttgcat actcaatgtc ttgaatgttt tctttgaaag tgagagttaa
     2221 aaatttcgtt tgattgtcaa aattcgtgtc tacaaggcgg gcaatctcaa atcgcatact
     2281 ttgataatgt ttctgtttgc gttttaaact gtcatattgt ccttgagcgg ataattcatc
     2341 atagtttttt cttttttcaa gagtaatatc attttcataa atccaagcta atttttgttt
     2401 tcgttccaga tttacttcgt tttcgatcgt tttacgtttg ggagtaatga ttgcttcata
     2461 atcataaatt tcaatatacg tgggagtttc aatgattttc tgattataag cttgcaaaaa
     2521 tcatcactcc ttgttgcgta ttcgattgtc aaagaaccag tcattttctc ctgatgttga
     2581 tctataaatc aagttaaggg ggaaggcctg cgtagcagcc cttctagcct atggggtgtt
     2641 gggcggtctt aacggacaga aacggctctg tgggcgctgc cccgccgttt cgtcctaacc
     2701 acccaacact ccatagtata gttagttttg tgtagtggta ccttgttttc tgggaatcaa
     2761 agttgccgta tcagcggttg ccgataaccc ataactgaca aattgtccat tcgagcgtcc
     2821 ccaaggtaca atcaccaaat tggtaaatgt aattatggct aaaccttgtt gggtaagttc
     2881 ttccggcgtg atcacaggat gttcagattt gactttgaca ctgatttttt cgtagcgaag
     2941 ttttggtagg atacattcgt agctccaacc tagaatttcg ccctcctttt gccagcgagt
     3001 gacattgacg acttggtatt ctttttcgag tgtttctttt ggtaaactga gatcggtaat
     3061 ttttattggc atcacaattc tcctttttta tacgaaagtt tatacgattt gattaaaaaa
     3121 tatagatggc catctacgac ttgtattata tacgagaact tatacgtagt caagagattt
     3181 tctaaaaaaa tatatacgat tttttatacg agtgttataa tgaaaaaaat gataaggagg
     3241 aatttgaata tgtttggttt agtacaacct aataaagtga aggtgggcca acgaatcaaa
     3301 gaaataaaag acggaatgtc tctctctttt acagaattag ggaatcgatt aggtttaaaa
     3361 aagccgacga tcagttccta cgttcaaggc tatgcgttgg ctcctaagag tgtgatcaac
     3421 caattatcta gtatcagcgg aaaacctgtc ggctggtttt attttgggca tgtggaagaa
     3481 tatatccgag agtatttgtt tctcattggt cagaaaaaaa tagtggacga ttatcctgaa
     3541 atcattgaga aaataaagca agaattttat acgggcgagt tcaaaaatcc tgcttgggag
     3601 aatgagctag gctatccttt ggaggaattt atccaagaat gttttgtaga atattcgagt
     3661 gaaatcatga aggactatgt cgtacagatt acgaaagagg tacttgaaga atccaaaacg
     3721 ctaaacaaac tatcatcaaa agcaaaagaa gaagctgtca cgattctttc atctgggatc
     3781 attgactata tcgagatgag tggtgagatc aagtatggag agaaagatcg cattgcgaaa
     3841 atggtgaaag aatcaataaa aacctttgat gtgaaacaag acctgacatt taatgattcc
     3901 tatttgattg gaaagttgat caatattctt ggtacagatg aagatacgga gctgtttctt
     3961 tcttctttat caatgatatt tactgataag catttttcca ctcgatttgg tggggaagaa
     4021 ttagtcgaaa tatttcaatc gatgcgacca gcgttaatca aactctatcg ggagaaaaca
     4081 ccagatgaat tttatgattg gtttgagaag taaaataaga aaagtggctt agattacaag
     4141 ttggtgaaaa aatttttttc agcataacat cagtaatcta taaaggggtt gttgattata
     4201 ctgtagaagt taagtactca agagattttt tgtacgtaaa caaagcaaaa aagggtgcag
     4261 tttcactaga aaatgtactc ttttttgtga tttttcttag ttatagagtt tttttgaaac
     4321 tttaaaaatg agaaaacata ttgattttaa agagtgtaga catagcttct tttgctaaat
     4381 agattaaact tactggtgag tggtcttgaa catactttta aatcacattt tactgagttt
     4441 tattggattt tataattcat tggaaacctc gtacttaatc tgtttttatc tatcgactag
     4501 aatctgtata tattccagct atcaatgagg ccgcagaaaa gggtgcttaa aaataatctg
     4561 ttgtttaaaa tattattatc agaatactta gatacaaaat tctggcacaa agtaaaaaaa
     4621 atattgactt aaaaaaatgg atatggtaat ctataaacga aaatagtggt aacgtttcca
     4681 aaatgcatct tcgttaaatt tttatttttt taaacgaaaa tggaaacgtt tctaaaatgt
     4741 attgggagga gattgaattg gaaaagacat tgggaccagg tggtgagata agggcggtac
     4801 aacgggataa aaaaaatatt tcgaagtggg aaaaattaaa gaaacagttg cggcgtgata
     4861 agtggatgta cttgttgctc ttaccaggta tcatcatgac gtttatcttt aagtatgtgc
     4921 caatgtacgg tgctgtgatt gcatttaaag actataatcc tatgctagga attttggaaa
     4981 gtccttgggt aggactagat cactttaggg aatttatcag ttcaccaaat tttacgcttt
     5041 tgctgagcaa cacattaaaa attagtattt atggtttatt gttaggtttt tttccaccaa
     5101 ttattttagc actgagcttg aatcaaatta tcaataaaaa aataaaacag aaaatccagt
     5161 tgattctata tgcgccgaat tttatctcag tagttattat tgtggggatg ctgtttttgt
     5221 tcctatccgc aaatggacct attaatgggt tagtagaaaa ggttacgggg caaccaatta
     5281 tgttcatgtc taatccagct tatttcagaa cgatttatat tttatcggga atttggcaag
     5341 gaatcggctg gtcatccatt ctttacaccg caacgctggc gggagtcagt accgatttat
     5401 atgaggcagc aaatatcgat ggggcaaata ttttacaaaa gatttggcat atcgatttgc
     5461 ctgcattgag gcctgtgatg gtgatcagct tcatcttggc cgccggcggt attatgaatg
     5521 taggatatga aaaagcctac ttgatgcaaa cttcaatgaa catccctgcc tcagaaatca
     5581 tttccactta tgtatacaaa gtcggcttgc aatcaggtga ttatgcctac tctgctgctg
     5641 ttggtctgtt caatatgatt attaatgtcg ttttattact gattgtcaac aatataacca
     5701 agcggctaaa cgatggtcaa ggcttgtaat gaaaggagaa aattatgaat agtgctttat
     5761 caaaaatcga ccgtcaaatc ttatggttga atcgagtgat tgtaactttt ttagtcgtca
     5821 tcaccattgt tccgctgatt tatgtactgg tagcttcttt tatggaccca gctactttga
     5881 tcaataaagg tataagcttc aatccgaaag attggacaat acagggatat caacgggtat
     5941 ttgcagatga ttccatttta cgcggttttg taaattcgtt gttttactct tttagcttca
     6001 gcttattgac tgtatttatt acgatgatca ctgcgtatcc tttgtctcga cctaacttgg
     6061 cggggaaaaa gattattatg actttttttg tcattacaat gttcgtgggt ggtggcttga
     6121 tacctaccta tttattggta aagaacttgg gcatgttaga tagtgtatgg gcgattatcg
     6181 taccaggtgc tataaatgtg tggaatatta tcttagcccg tacctatttt agtgctttgc
     6241 caaaagaact ttctgaagct gctactatcg atggcgccaa tgacttgcaa atactgttca
     6301 aagtcatgct tccattagcg aaaccaatta tgttcgtatt gtttttatat gcctttgttg
     6361 ggcaatggaa ctcatacttt gatgccatga tttacatcaa agatcccgac ttacagccgt
     6421 tgcaactcgt attaagaaat attttgatcc aaaaccaacc ttcacaagac atggtgggag
     6481 ccaatactgc catggcagaa atgaaacaaa ttgctgagtt gatcaaatac gcaacgatcg
     6541 tcatttctag tctgccatta atcataatgt atcctttctt ccaaaaatat tttgataaag
     6601 gtgttttagt tggttctgtt aaagggtaag tattgttcac tatttgtatg aataaaaatt
     6661 ataaaggaga ttttaagatg aaagcaaaat ggatgctgcc aatcgttttt acttccgtac
     6721 taattttggg ggcttgtgga ggctcaaaag aaaagagtaa atcaagccct gattatgaac
     6781 tagaaaatgt ctcttttcca ttgaaagaaa aagtatcttt aaaaatgatg tctcaaagtg
     6841 cccctttggc tcccaatgat cctaatgaca aattgatttt ccaacgatta gaagaagaga
     6901 ccaatctcca tattgattgg acaaactaca gtagtgattt tgccgaaaaa agaaatttgg
     6961 atatcgctag tggtgattta ccagatgcca tcttcaacgc cgctgcaggt gactatgatt
     7021 tattaaactg ggcggaaagt ggcgttattg taccgattga agatttgatc gaagattata
     7081 tgccaaatct gaagaaaatt tttgatgaaa accccgaata ccgacaaatg tctactgcac
     7141 ctgatggtca catttactct atgccttgga ttgaagaatt aggcgaagga aaagagtcga
     7201 ttcatacagt aaatgggatg gcttggatca acaaggagtg gttggataat ttgggtcttg
     7261 aaatgccgca aaccactgat cagttgatga ctgtgttgga ggctttcaag acgcaagatc
     7321 caaatggtaa tggtgaagca gatgaaattc cttttagctt tattaacaat ggaggaaacg
     7381 aagacttaaa atttttaatg ggggcattcg gtctaggtga taatgatgac cacttagtcg
     7441 ttgataacga tggtcaggta caatttactg ctaacaaaga agggtataaa gaagccatca
     7501 aatatttcaa tgaaatgaat aataaaggtc ttattgataa agaggctttc gaacaagatt
     7561 ggaatacgta tgttgccaaa gggaaagaac ataagtatgg cgtgtacttt acttgggata
     7621 aagcaaatat cacgggtgca gatgatagtt atgacgtctt gccagtctta gcgggaccag
     7681 atggaacgaa acatgttact cgtacgaatg gcatgggttt ctcaagagat cgtttcgtaa
     7741 ttactagtgc gaataaaaac ttggaactta cagctaggtg gatagataaa atgtatgaac
     7801 cgttacagtc tgtccaaaat aactggggaa cctacggtga tgaagcacag gcgaatattt
     7861 ttgaattaaa ggatggtatg ttaaaacatt tgcctttaga ggggacagca ccgggggaac
     7921 taagacaaaa aaccgaagct ggaggaccat tagcagttct tgattcttat tacggcacag
     7981 tcactactat gccagatgat gcgaagtggc gtttagattt gatgcatgac acgtatttgc
     8041 catatattac agaagacaat atctatccac gtgtcttttt agaaaaagaa gaaacagatc
     8101 gattagcaaa aatcgaaacg gatatgtggg attacatcta tcgcaaaaga gcagagtgga
     8161 tcaccggcgg taaaatcgat gaagaatggg aagaatacct tgctgaattg gaacgtgtag
     8221 gtttggaaga atggattcaa ataaaacaaa ctggctatga taattttttg aagggagcac
     8281 aataagtgtt agtagaagaa acggcgattt tggataaagc aaatcgattt attgaaatga
     8341 tgcgaggaaa agttaaccct cagtatcgac aaaactatca tttttccgca cccatcgggt
     8401 ggataaatga ccccaatggg tttatatatt acaaagggca ttaccatctc ttctatcaat
     8461 actatcctta cgatagtcga tgggggccca tgcattgggg gcatgcgcgc agtagtgatt
     8521 tggtccattg ggaagatcta ccagtagcgt tagccccaga tcaaccttat gacagcggcg
     8581 ggtgtttctc aggaagtgca attgaaagag acggaaaact atatttattt tatacaggct
     8641 gtcaagaaat tgatggtatt agccatcagc atcaatgttt ggcggtctct gaagatggta
     8701 ttcattttag caaatacagt ggtaatcctg tggtagcaga aaaacagcta ggtgaaaatg
     8761 ggctaataca agaatttcgt gatcctaaag taattgttca caacgatggt tactatatgg
     8821 tagtagctac taaatctaca cagtctactg gtagaatagt gatgtttcaa tcgtcagatt
     8881 tgtatacttg gcacttttac tctgtgctgc tagaagggac ttcagagcaa ggaataatgt
     8941 gggaatgtcc tgatttattc catttagacg gacgagatgt cttaatcatg tctccgatac
     9001 aaatcaagaa gaacggactg gaatatcata atatcagttc taccatggct tgtattggtg
     9061 aggtaaactg ggaaacaggt cagatgatag ttgataattt ccatgaaatg gattttggaa
     9121 tggattttta tgcaccacaa acaacaagag atcctaatgg tggacgggtg atgattgctt
     9181 ggatgcagat gtgggatcgt acattgccta cacatgagtt aggccatctt tgggcaggct
     9241 ctatgagttt gccccgagag ttaagagtga aaaaaaatcg attggtacaa aaacccatct
     9301 caactgtata tagtcattta gtttatcaac aaggcagtga aaatattgca gtgactgaca
     9361 catcagtcgt atttcgaaac gcgctgtctg attcttcata tttacatcta gtcgcagatt
     9421 tggagaaagc tgaagttttt acaattgaat tactgcggtc taagacggat tgtctcaaac
     9481 tagcctatga cactgctaca caggtttttg aattggatcg tcagaaacta ggaagagagc
     9541 ttacaggggc ggaagaagac cctctgaatg tacgaaaagt tgaagtacct ttgattgata
     9601 atcagctcgt tcttgagatt tttagagata cctcatcaat tgaagtcttt attaatgggt
     9661 tagaagttat gacggctact ttctatgagc tggaaaaagc tcgagatatc ttgtttcatt
     9721 cgatcggaga aagtcgtatt caagcttttg aaacagcgag tgtgaaataa atgtttgatt
     9781 gcttaggcga tgaatcaatt atttaatagg ttttgaagga taatgttttt agaaaagaac
     9841 agatagctag atttcccatg gatttgctat tagtattttg aaaaaattag taatttatga
     9901 caaaattcat tatactaaac ttgtgcagaa atgtgaggga tcaactatga aagcaacaat
     9961 gaaagatgtc gcaaaattag caggtgttgg agtaggaact gtttcccggg tattgaataa
    10021 cggttctgtt aaagcttcta ctagagaaaa agttgaagca gcaatgacag agttaaacta
    10081 tcaaccagat ttttatgccc gggggttaaa gatgaagcat acgaacacgg ttgctttgat
    10141 tctacccacg gtatggcatc cattttttgg cgaatttgcc taccatgtag aaacagcatt
    10201 agaaagacaa aactacaagc tttatttgtg taactccagt ggtaatagtg aaaaagaaca
    10261 agaatatatc cagatggtca gccaaaataa agtagacggc atcattggaa ttacttattc
    10321 agatatcgat gaatacattt cgagtaatct gccttttgtt agtattgacc gttatttcac
    10381 tgaagaggtg atttatgtga ccgctgacaa tgcggccggt ggacgtttgg ctgcaaatga
    10441 actttatcgc cgaggatgtc agaatgtagc atatatcggt gggtaccaag aaacaccgaa
    10501 tgaaacgaag agtcgtcgaa aatattttga aatcgagtgc cgtcaactgg ggatttccta
    10561 taaagcgtta gatatgttag aacctttaga ccatctctca gaacgtgtaa caaatttttt
    10621 gttagagaat cccgatatcg atgggatttt tacgatcaac gatccaatgg cattagctgt
    10681 cattgatatg cttgaaaaaa tagggaaaaa cgtaccagag gatgtccaag ttatcggatt
    10741 tgatggtcaa aagatgacag aaggagatcc ttatctagtc tcaacgattg cccaacctac
    10801 aaagcaaatg gcggaagtgg cagtggcaaa attaattgct gtcattaatg gagagacagt
    10861 agaaaaacgt accgtattgc cgattgaatt tggcgaaggt gacacaacga aacctttagt
    10921 gagaaacgat tttgcttagt gcaaatacgt ttcttttttt gaaaatgagt gaatgaaagg
    10981 tgtagataaa atgttatatg gtggaataga agccggtgga acaaagtttg tctgtgggat
    11041 tggtaatgaa caattacaag tgatagaacg gaaaagtttt cctaccacaa caccagaaga
    11101 aacgatggag caagtgtttg atttctttga taagtacaaa ggaaatatcg catcaattgg
    11161 tgtaggagca tttgggccta ttgatattca aatcgaatca agaacttacg gatatatcac
    11221 caacacaccg aagttagctt ggcaaaatta tcattttgta ggagctttgg aaaacgcctt
    11281 gtcggttccc atctattgga ctaccgatgt aaatgctgct tgttatggag aatatatggc
    11341 agggtatgga aaaggtaaaa atagtgttct gtattacacc gttggtacag gtgttggtgg
    11401 tggtgctgta gtggatggga aaatagtcgc aggttttagt catcctgaaa tgggacatat
    11461 gctcttacaa cgtcataatg aagatcaatt tgaaggaatc tgtccttttc atcatgattg
    11521 tttggaaggg ttagcatcag gacctgcgat tgaaaaacgc tttggaagaa aagcccagac
    11581 tatctcattt gatcatcctt attggacgat tgaggcagat tatcttgctc agtgtgtgta
    11641 taacacaacg ttactatatg caccggaagt aataatttta ggcgggggtg taatgaaaca
    11701 gccgcaacta ctcgagttga ttcgccaatc gtttaaagaa aaaatgggtt cctacgtgga
    11761 tacgcctact ctcgaagaat atctactaac tccaaggctt gctgacaatg cgggcttgat
    11821 tggctgccta gctttagcaa taaagaaact caatcattag aatagtattt attagaacta
    11881 ttcataacat accggaagtt taaaagggta ttctgaaact taaatagtct caattcattc
    11941 ttctttcttg agaatctgag tagagacttt tattctgttt caaattaata taattacgaa
    12001 atgatattga gtacaagaaa gttcttttta ccagatcttt taaatcgaaa aatctgatat
    12061 atatatttat agtactaaaa atctgattag ataaaaagct aattcaatag gaaaataaag
    12121 gtagtgaata aaagcaaagc ccttgttagt agttaatcta acaagggctt tggtagggaa
    12181 aatggtagga aaccatctta ttttttacga aaatcaggaa ctttagtaat tgaataatgt
    12241 tgatttatag gtattcctca tccatattat gttggctctt tattcccact ccactgttgc
    12301 aggtggtttg ctggtaatat catacacgat acggttaacg tgtgcgactt catttacgat
    12361 acggacactg attttttgca agacttccca agggatacgg gcaaagtcag cggtcatgcc
    12421 gtcaatagaa gtgacagcac ggatacctac agtgtagtca tacgtacggc catctcccat
    12481 aaccccaaca gagcgaatgc ctggtaggac ggtgaagtat tgccagatgt cgcgatctaa
    12541 accggcattg gcgatttctt cgcgcaagat agcgtctgat tcacggacga tttctaattt
    12601 ttcttctgtc aattcaccaa ggacacgaat acctaagcct ggtccaggga atggttggcg
    12661 ccaaacgatg ctgtcaggca tgcctaattg ggtacctaat tcacgtactt cgtctttgaa
    12721 caatgtgttc aatggctcga tcagcttgaa ttgcatgtct tcaggtaatc cacctacatt
    12781 gtgatgtgat ttgatggttt gggcagtttc agttcctgat tcgatcacat cggtataaag
    12841 ggttccttgt gcaaggaaag aaacgccttc ttcaccggca agtttggttg cttcatcatc
    12901 gaagacatat acaaattcat ttccaatgat tttacgtttt tcttctggat cagacacgcc
    12961 agcaagtttt gataagaaac gttctttggc atcgactttt ataatgttca agccaaattt
    13021 tccgccaaga ctttccataa cttgttctgc ttcaccttta cgcaacaata cgtgatcaac
    13081 gaagatacat gttaattgat cgccgatcgc tttttgtaaa agaacaccaa caacagagga
    13141 atctactccg cctgaaaggc ctaataaaac ttttttgtca ccgacttgtt cacgaatttt
    13201 tgcgatctcc atgtcgatga agttatccat tgtccagtca ccagtacatt ggcagacatc
    13261 tagtgtaaaa tggcgcaaca agtcatttcc atattcggaa tggcgaactt ctgcatggaa
    13321 ttggattccg tacattttgc gttctgcatt ttggatcgat gcgatggggc aatctttgct
    13381 ggtagcaacg acatcgaaat cagtcggtgc ttgggtaact aggtcaccat gactcatcca
    13441 aacggtttgt ttttcaggag tgttttggaa aagggccgct tctgcagaag tgatttccaa
    13501 ttctgctttt ccgtattcac ggtttttggc tggtttaact tttccgccta atttataagt
    13561 aatcaactgc ataccgtaac agattcctaa aactgggatc cccaaatcaa aaatcttttc
    13621 atcaatacca aaggccttct catcataaac actgtttggt ccgccagaaa ggatgattcc
    13681 tttagggttc attgccttta cttcttctgc ggtaatgcgg tggctcatca actctgagaa
    13741 aacaccgaac tcacgaatac ggcgagtgat cagttggtta tactgactac cgtaatcaag
    13801 tacgataatt tt
//
LOCUS       DAPBAF010000065        13427 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.065, whole genome shotgun sequence.
ACCESSION   DAPBAF010000065 DAPBAF010000000
VERSION     DAPBAF010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13427)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13427)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13427
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.065"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(<1..912)
                     /locus_tag="RD451_002478"
     CDS             complement(<1..912)
                     /locus_tag="RD451_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_042964654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HDT7567693.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIY"
     gene            1340..1903
                     /gene="efp"
                     /locus_tag="RD451_002479"
     CDS             1340..1903
                     /gene="efp"
                     /locus_tag="RD451_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HDT7567694.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
     gene            2004..2174
                     /locus_tag="RD451_002480"
     CDS             2004..2174
                     /locus_tag="RD451_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567695.1"
                     /translation="MKNKKVFDFIYILKDEWQKLEKEKTALIYEEIEMIHKIENIRTI
                     PNYIEAKIFFHH"
     gene            2389..3648
                     /gene="lysA"
                     /locus_tag="RD451_002481"
     CDS             2389..3648
                     /gene="lysA"
                     /locus_tag="RD451_002481"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HDT7567696.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            3635..4435
                     /gene="dapF"
                     /locus_tag="RD451_002482"
     CDS             3635..4435
                     /gene="dapF"
                     /locus_tag="RD451_002482"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HDT7567697.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            4438..5319
                     /locus_tag="RD451_002483"
     CDS             4438..5319
                     /locus_tag="RD451_002483"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HDT7567698.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            5316..6032
                     /locus_tag="RD451_002484"
     CDS             5316..6032
                     /locus_tag="RD451_002484"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HDT7567699.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            6038..6733
                     /gene="dapD"
                     /locus_tag="RD451_002485"
     CDS             6038..6733
                     /gene="dapD"
                     /locus_tag="RD451_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HDT7567700.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            6749..7750
                     /locus_tag="RD451_002486"
     CDS             6749..7750
                     /locus_tag="RD451_002486"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HDT7567701.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            7747..9108
                     /locus_tag="RD451_002487"
     CDS             7747..9108
                     /locus_tag="RD451_002487"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HDT7567702.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            9068..10219
                     /locus_tag="RD451_002488"
     CDS             9068..10219
                     /locus_tag="RD451_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDT7567703.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            10194..11363
                     /locus_tag="RD451_002489"
     CDS             10194..11363
                     /locus_tag="RD451_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDT7567704.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            11538..12917
                     /locus_tag="RD451_002490"
     CDS             11538..12917
                     /locus_tag="RD451_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDT7567705.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            13198..13427
                     /locus_tag="RD451_002491"
                     /pseudo
     CDS             13198..13427
                     /locus_tag="RD451_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         4482 a         2339 c         2924 g         3682 t
ORIGIN      
        1 gtaaatgttt tttgataaat agcggtctgc tgcgtctgga aaaatcgtaa cgacacgatg
       61 accaggtggt aaacgacgaa tttctcttaa tgctgctgca aaagccgcac cactcgaact
      121 tccaactaat agtccttgtt ctcgtgctaa ctgcctagta tagttaaacc cttctacatc
      181 agagattgtc tcgatctgat tgattgaaag gggagaaaga aacggcggaa tgaattctac
      241 accgataccc tcaatttcgt gaggggctgg atcaccacca tttaacacag agccctctgg
      301 ttctacaccg attattcgaa tgtcgggata tttttctttc aaaaaggtag aagttccagc
      361 aaaggttcca ccactcccaa ttcctgctac aaaactatgg atattttctt tgatttcatg
      421 aaagatttct ggccctaacg tatgatagta agcagcagga ttatctttat tttcaaattg
      481 aagaggcaga tagctgtttg atatctcctc tgcaagtttt ttacttttgc tgatggcacc
      541 gatgattcct tgctcactag gagaatggat gatctttgct cccaatgctt tcatcaattg
      601 ttgtttttct aagctaaact tctctggaac aacaaaaacc gttcttaatt tgtatgtgag
      661 tgcggccaga gcgatcccaa ttcctgtatt tccggcagtt ggttcgatga tcgtcgtttt
      721 ttcattgatt tttccttggg caaatccttc tttgatcaaa taactgccca atctatcttt
      781 gatacttcct ccaggattta aatattctag ttttgcataa atagcagaac ctttaggcat
      841 agaatagtgc tgattgtcaa agcgataaag cggtgtggaa ccaatagctt ctgtaattgt
      901 cgagataatc atgtgggcct cctaaaaaaa gataataaaa aaaggagctg actattaaat
      961 cagctccttg aaagacatag agaaaaattg agtagataaa aagataagtt acctggtact
     1021 cattctatga agggcaatta atagacatga caaatagtat gctgctttta tgcaccatac
     1081 aacagcaacg attcaattgt ttttggttgc tgactgtcat gtgtatccct ccaagtaaaa
     1141 tttttattaa cgatagcatg aaaaaaaata aaagtcaaag gcttgaaaga aaaaaatatt
     1201 tcgatagcat cgtttacccg tgtttatttt tctgacaaat aggcatgaga ccttaaaaga
     1261 tagagaatac tctagttttc tggccggttg tctgatacaa taaagttgat tatgataaag
     1321 aaaagaagga gcaaaaataa tgatctcagc aagtgattta agagccggta tgactttcgt
     1381 acaagacggc aaactgatta aagttctgga tgcaagccac cataaacctg gtaaaggaaa
     1441 tacagttatg cgtatgaaac tgaaagatgt ccgttcaggt gcaacatacg acacaacgtt
     1501 cagaccagaa gaaaaatttg aaaaagcaca tatcgacaca aaacctgtac aatatttgta
     1561 cacgatggat gatacagctt tcttcatgga tttggaaaca tatgagcaat atgaaattcc
     1621 tgtagaaaca gtagaagaag aaatgaaata tatcctagaa aacatggaag taaaaatcca
     1681 atttttcggt agcgaagtca tcggcgttca attaccaaca actgtcgtat tacgtgttgt
     1741 ggaaacacaa ccttccatca aaggtgcaac agtcactggt tcaggtaagc cagcgacaat
     1801 ggaaactggc ttagtagtca atgttcctga cttcatcgaa acagatgaat tgttggaaat
     1861 caatacagca gaaggttctt atgtaaaacg tgcgtcaaaa taattcgcta acggattgat
     1921 aagaatttga aaacagagct tgacctcttg aaaggcagat catcggatct gcctttcaag
     1981 aggttttttg tggaatcagc aaattgaaaa ataaaaaagt atttgatttt atttatattt
     2041 tgaaagatga atggcaaaag ctagagaaag aaaaaactgc acttatttat gaagaaattg
     2101 aaatgattca taaaattgaa aatatccgaa ctattccgaa ctatattgaa gcgaaaatat
     2161 tttttcatca ctaaatagtg ttgaatttat gtttttatgt ataaatagct tctaatagtt
     2221 cgggtatttt gtttttataa ccatttttat tcttattttt aaaaaaatat ttcgaaatat
     2281 actagacaat tcagaaaatt ttgtttaata ttattccaat aaaattcaaa tctttatcaa
     2341 atgaaattcc aataaaaacg gaaaaaaagt gaaaagagga atgaaaaaat gacagaattg
     2401 ataattggcg gagtcacagc aagcacattg gcagaaaagt ataagacacc tctgtatgtg
     2461 tatgatgaag aaaagatgag acaaacgatg ctgtcattca agcgaggctt tgtatcgaaa
     2521 cgttttgata caaaagtgct ttacgcctct aaagcattcc aaacgattga gatgctgcat
     2581 ttagttcgtg aatatggatt cgggctagat gttgtcagtg gtggggaaat ctataccgct
     2641 ttgcaagctg attttcctag agatactatc tacttccatg gtaacaacaa gacgccagag
     2701 gaactgatct atgcacttga aaatgatttg ttgcatattg ttgccgataa tttgatggaa
     2761 gttgaattat tagcagaatt aagccaacgc tatttaaaaa aaatctgtat catgcttcgg
     2821 ttgaatgtcg gagtagaagc acatactcat gaatatatcg tcactgcgca tattgattca
     2881 aaattcggca tgagctatga aagtaaagag tgccaacaag cccttcagtt gataaaagaa
     2941 agcagctatc tagagttaga aggatttcat gctcatatcg ggtcacaaat ttttgatgtt
     3001 actgcttggt tagctgaaat cgacaaattg acgaattact taaccgattt tgaccaacct
     3061 ctttccttga atcttggcgg agggtttggg attcgttata cacaaaatga tcagccgatc
     3121 ccagtcgaag aggcactaaa aaaactgatt gaatatacgg aagaagcttt ggaaaaacga
     3181 aaactgacca ttcgtcaatt actgatcgaa ccgggtagaa gtattgttgg agaagctggt
     3241 acaacactat acacgattgg tttcatcaaa aagacaccac ataaaaaata ttactttgta
     3301 gatggcggga tgacagataa tatccgtcca gctctgtatc aggcagaata cgattgtgat
     3361 ttagcagcaa aactgtcgga agaaaaaaca gagaaagtga cgattgcagg aaaaatgtgt
     3421 gaatcaggcg atgtggtaat taaagaagct tatttgccga aagcagaatc gggtgatctt
     3481 ttagctgttt attccacggg agcttatgga tactcgatga gcagcaacta caatcgagcg
     3541 acacgaccag cagttgtttt tgtcaataat ggccaatcaa gactgattgt tcgcagacaa
     3601 gcattttctg atctactaag gggggaagtt tcctatgatc cttcataaat ataatggctg
     3661 cggaaatgat tttatcttat tagattacgc agaagacaca gattatagtc aattagccgc
     3721 ttctttatgc acaaaagaaa aatatgatat agacggattg atcgccgtaa aaatcgatcc
     3781 gttggaaatg atctattaca acaaagatgg cagccgcgcg ccgatgtgcg gaaatggcat
     3841 tcgctgtttt gctcgatacg taaatgatca gaacatgatg aatgaacagg aattcaacgt
     3901 agagacatta gcaggcacaa gaaaaattac ggtgttggat ccctcacctt tttattgcag
     3961 cgtagatatg ggagtgccag atgattctcc ggaaaaaatc aaagctaatc aaacttatcc
     4021 aataaaaaac caggaaatag agatcaatgg tgaaaaagta acgatcacta gtttattttt
     4081 aggaacgatt cataccgttg tttttgttga aaatgcgcgt gaggaagtct ggagaaaaag
     4141 aggtgaactg atctgtcatc atcctttgtt caaagaaaaa accaatgtca actttgtaga
     4201 agtagtcaat gaacaagaat tgatcgtccg tacctatgaa agaggagtag gttggacact
     4261 tgcttgcggt acaggttgct gtgcctctta tgtggttgct aaggaaactg ggaaaatttc
     4321 agcagatcag gtagttgttc acttggaaca aggagacttg atgatctctg gtgaggatgc
     4381 gatacaaatg gctggcccag cagttcatga atggacaaga atattggagg aatgaagatg
     4441 ataaaaggtt cgatcgtggc gctgatcacg ccgatgaatg aagagggatc agtagattat
     4501 gctggtttgg aaaaattgat ccaattccat ttagatgaac aaacagatgg attattagtt
     4561 ttaggtacaa caggagaatc ttctacgctc acacaatctg aggaggagca gatccttcaa
     4621 ctgacagtaa agaaagtggc tggccgtgtg ccggtgattg caggagctgg aacgaataat
     4681 acgaaagaaa cgattgaaaa agcgaagcat tttgcttctt tgggggcaga cgcacttttg
     4741 gtcatcaccc cttactacaa caaaacaagt gatgcaggac tagctgctca ttttacagca
     4801 attgcagaag cctcaccgat tccgcttatt ttgtataatg ttccttctag aacaggcatg
     4861 tcgattccaa tccatgtatt agtaaattta gcagaacatc ctaatatcat tggtttgaaa
     4921 gaagcctcag gagatatggc ttatgtgatg gatgccgctc ggttgattgg agaagaattc
     4981 ttcctttaca gtggaaatga tgatttgatc ctaccagtaa tgagtgtagg aggaagcggt
     5041 gtaataagtg tatgggcgaa tatccaacct aaaatagtcc atgaattagt aaaagatacg
     5101 caggacggaa gatggcagca agcaaaagaa aagcaattaa atgcacttga actgatccat
     5161 gccttgttca gtgagaccaa tcctattcct gtcaaagcag ccatgtcatt attagactta
     5221 ccttccggac ctctacgcct gcctttagtt tctctttcaa aagagaaaaa gaaacaatta
     5281 gctcagcttt tgttaaaaga aaggacggtt gaaaaatgaa aatcggactg attggcagtg
     5341 gacagatggg aaatagagtc gaagaagttg cacaagaaag aggagatacg gtccttcttt
     5401 tacggacggc acctaaagaa gcaactacgc ttgcttttac ggaactgcca gaactgctta
     5461 ttgatttttc tcatccagat aatttagaga aaatcctttc gtatagctta tcatatcaac
     5521 ttccgttagt cattggcacg acaggttata cacaatcaca gttccaagaa ataaaagaac
     5581 atgccaaaca tgtacctgtg atgtatagtg ctaatttttc gttcggcatc atggtgatga
     5641 atcaactaat caagcaagca gctgcaatgt tgcaaggctg gcagatcgaa ctgattgaaa
     5701 aacatcatag tcgtaaaaaa gatgcaccat ctggtactgc aaatatgctg cttcaaacaa
     5761 tccaagaagt gcaaaagctg cagcccgtat acaactggca agggaaaaaa agagaagaaa
     5821 accaaattgg tgtacacagt attcgtgcag gttctttacc tggtgaacat gatgtattgt
     5881 ttgctgctac tgatgaaata tttacgatca aacatgaatc tttttctaat cgaatctttg
     5941 ctgcaggcgc agtagaagca gcggactggt tgaaagatca gtcaccaggt tattacaaat
     6001 tagaagattt attaatggac aaaggggtgt aaaaaacgtg gaagctcaag aaatcatccg
     6061 ctacattcaa acggcatcta aaaagacgcc tgtgaaagtc tatctgaatg taaccgagcc
     6121 aatcgaattt aaagaaagta aagtttttgg tgaaggaagc agcttcgttg tttttggtga
     6181 ctatgagacg attgctccgg ttttagaagc tgaatcagaa aaaatcattg aaatcgaaat
     6241 cgaaactgct gcaagataca gcgcagttcc tttgctagat attaaaaaaa ttaatgctcg
     6301 tatcgaacca ggtgctatta tcagagatca agtgtcaatc ggcaacaatg ccgtgatcat
     6361 gatgggagcg attatcaata ttggtgcagt aatcggtgaa aacacgatga ttgatatggg
     6421 tgctgtctta ggtggacgag cgacagtggg caaaaactgc catattggtg caggagctgt
     6481 cttagcaggt gtgatcgaac cagcatcggc caaaccggtt atcgtagaag acggcgtact
     6541 ggtaggtgcg aatgcagtga ttgttgaagg tgtccatatc ggaaaagatg cagtcgtggc
     6601 agcaggagca gtggttttag aagatgtggc agcagaaact gttgtcggtg gaatacctgc
     6661 acgtgtatta aaaataagtg atgatcagac aaaagaaaat acagcattga ttgctgcgtt
     6721 acgcgaatta tagaggagat ggagaaaaat gcgcgaaata gatacctgta ttgtgggggc
     6781 aaccggatta gtcggccaaa cgatgctcaa agtgttagaa gaatatgatt ttccagtagg
     6841 acgattgaaa ttattagctt caaaacgttc agccggtaaa gtttgtgtat tcaagaaaaa
     6901 gaaacacact gtacaggaat tgacagaaac ttcatttgaa ggatatgatt tagcgctatt
     6961 ttctgcaggt gcttctgtat ccaaagagtt tgcgccaatc gcacgaagtc agggactatt
     7021 tgtcatagat aattcctcag catggcggga agattcggat attccattaa tcgttccaga
     7081 ggtcaatctg gaagactata cattgaatcg gctgattgca aatccaaatt gttcaaccat
     7141 tcaagcggta cttccgctta aagctttaca agaagccttt ggtatccagc gagtcaatta
     7201 ttcgacctat caagcagttt ctggttccgg gcaaaaaggc attgaagatc ttcatcgtac
     7261 gcaaaatgac gaggaaccag ttttgtatcc ttataatatt agccaaacgg tgattccgga
     7321 aatcgatcag cctttggaaa atgggtatac aaaagaagaa cagaaaatga taaatgagac
     7381 ccgtaagatt ctgcatcagc ctgctttgcc agtatcagca acctgcgtac gtgtgccaat
     7441 cgaaaatgga catggagtct ctgtggcagt tcaactgcaa aaagagttta cgacggaaga
     7501 aattagagag tgtctcagcc agtttccagg gattcaatta gaagatgatc tagcagcaca
     7561 taaatatccg acgagcattc ttgctagagg aacagatatg gtttatgttg ggaggatcag
     7621 aaaagacact tctttagaga acggattgtt gttctatacg actgccgata acatacgcaa
     7681 aggagccgct gcgaatgccg tacagattgc tgcagcttta atgcagaaaa tagcggaggt
     7741 ggcaagatga gtaatacgct gaaagtagcg aaattcggcg gaacatcgat gtctcatgaa
     7801 gagcaattca aaaaagtccg tacaattgtt ctttcagatc ccaatcgcca agtgatcgtt
     7861 gtttctgctt taggcaaacg tacgtcagat gatgacaaag taacagactt actttatttg
     7921 atttatgctt accttcagca tcatgttgat tggacacccc tttggaaaag gatttgtgat
     7981 cgtttcattc aagtaagaga tgttcttgcc ctgcagttac ctattgaaga tgaactagca
     8041 cgcatacaga aacaactgga agacgaaaag ataactgaag attatttagt aagtagaggt
     8101 gaatatctga ctgctcaact gatggctgag tatcttggtt accagtttat tgacgcaaaa
     8161 gacctgattt tctttgacta tgatgggaaa atcgatcagg aaaaaacagc acaggaaatc
     8221 acaaaagcat ttaaaagata tccgaaaatg gttgttccag ggttttacgg ggcgaaccct
     8281 gcaggaaaag aaaaattatt gggccgtggg ggaagcgaca ttaccggcgc gatactggcg
     8341 aagatgttgc aagcggaaag ttatgagaat tggacggatg tttcaggaat catgatggct
     8401 gatccgcgaa tcatcgatca tcctaaaatc atcgaggaaa tctcttttag agaactgaga
     8461 gagatggctt atatgggggc taacgttctt catgaagcag ctgttttccc agttcaagag
     8521 gctgatatcc ccatccaaat aaaaaatacc aatgatcctt tcgctcaagg gacaaaaata
     8581 tcgaatcacg aaatagaaaa ggaaaatgga ctgacaggaa tagctggacg caaggatttt
     8641 ctttccatca ctttattcaa acgtcatatg tccgatgaaa tcgggtttat ctggaaagca
     8701 atgagcattt ttgctaaaca tgagatatca atcgaacata ttccttcagg gatcgacaat
     8761 atcggagtga tcgtctcagc agaagcgatt gccgataagt tatttctcat cacgaaagaa
     8821 ttaaaagaaa cacttggcgt ggaagaaatc gtcgtgatcg aagacttagc tttgatctct
     8881 gtcgttgggg gtccgcataa agaattgatt ggattatctg ggaaagtgtt atcgatattg
     8941 aacaaattag aaattcgcac atcgatctta tcacaaggag cacaggagtt gaatctgatc
     9001 atcggtgtac cgaataatca atatgaaaca gtagtgaagg gtatctatga agggatggtg
     9061 aatacggatg ctgaaagaat atcgaatggc actccatcaa attcctgaaa tcgggtttca
     9121 tgaattcaag acaaaaaaat atttatatga acaagtaaaa aacagcgagg ccgttatcca
     9181 tgaaatcggc gaaacaggac tactccttta ttttgataat cagcaagaag aaacgattgc
     9241 ttttcgaaca gatatcgatg cactgccagt caaagaagaa acgaatctct cttttgcttc
     9301 taagcatgaa ggttatatgc atgcatgtgg tcatgacgga catatggcga tgcttttagg
     9361 gttgactgac tttataacta aacacattga ggatcttatt tataatgtag tactgatcta
     9421 tcagccatca gaagaaattt ccggtggcgc acaaagcgtt attcagtcag gattgttgga
     9481 taaatatgaa gtacaagcaa tatttggctt tcatctatgg cctggactag ctaagggaga
     9541 agttttctct cgaccaggac ctttgatggc acaaagcagt gaaacagaca ttatcattaa
     9601 aggccagtct gcacatattg cttctagtga aaaaggaatc gatagtctgg aggcagctgt
     9661 acgatttttg aagaatgttt atgattttga ccggcaatta ccggcagagt ggaatcatct
     9721 aatgaaattt ggccaaatcc aaggtggaac gatccgaaat gttttagctg gagaagttat
     9781 tgtatccgga agtatccgtt cttacagttc agatatgcaa aattatttga agaggggatt
     9841 agaccattta gcagaacagt ttcactctac agctactatt tcttttcgct ataatgacgg
     9901 ctatccagct gtaatcaacc atagaggctt atatgcagca ctgttagatt caaacaaact
     9961 acatgaatta gatgctccag ttcttcaagc cgaagatttt ggcatatata cgcaacaata
    10021 tccatgtgta tttttctttt taggtgtcgg tgatacccct gctttacatg atccgacgtt
    10081 cgattttgat atggatgttt tagaaaatgg tgtagaatgg tacaaaacga ttctttttac
    10141 agaaaatctt cttgtaaaaa tcgatagcag ttcaaaagag gagcgagtaa ataatgatga
    10201 atttatccaa tcgatttagt cctaggcttt ctagaataga agtatcaaaa atacgacaat
    10261 tcgatcagca aatatcgtcg ataccagatg tgatcaaact caccctggga gaaccggatt
    10321 ttccaactcc tgaacatgtc aagcaagcag gaatagcagc gattgaagaa gacttttctc
    10381 actataccgg aatgagagga ttagaggaac tgcgggaagc ggcttgtata tttcagcaac
    10441 agcgttatgg attaacttat gatccgcaaa cggaagtttt gacgacagtt ggtgcaacgg
    10501 aagcgattgc ctctgcgttg ttatctgttt tggaagaagg agacaaggtt cttattccag
    10561 cgcctgctta ttcaggatat cagccattag tggaactagc tggtgctgaa ttgatcccga
    10621 tagatacttc tgacacaggg tttgtctgtc agccggaaca atttgaacga gcatttgaac
    10681 aatatggatc agctgtcaaa gcagtcattt taaactatcc taacaatcct actgggacga
    10741 cattgtctgc aaaacaattg aaagcaatcg ctgaggtttt aaaaaaatat ccggtatttg
    10801 ttataagtga tgaagtatat gctgaattga cttatagtgg aacgcatatg tccatagcta
    10861 cttatcttcc agaacaaaca atcgtgataa gcgggttatc caagtcacat gcgatgactg
    10921 gttggcgagt gggctttatt tttgctcaaa aagcccttat tgacgaacta attaaagtcc
    10981 atcaatatct ggtgactgcc gctacaacga tgtcgcaaaa agctgcggct gaagcgctaa
    11041 taaatggggt gaaagatagc gagaatatga aagagcaata tcaaacacga agagactatc
    11101 tggtccagca attggcgcct ttaggatttg aagtgaccca gccaaacggt gcattttact
    11161 tgttttgcaa actcccagct gccattcaaa ctgactcttg gcagttttgt gtagaattag
    11221 cggaacaggc aaaagttgcg tgtatcccag gaattgcatt tggcccagaa ggagaaggtt
    11281 atatccggat ttcttatgct agcagcatgg aaaaattaca tgaggcctgc aaacggatca
    11341 aagacttttt aacagaacag tgattcatag attttatcaa aaaaacaatc gttaattttg
    11401 cggtatattc tgcaaggaga cgattgtttt ttaaatttag ttcaaatgaa cgcgtttctt
    11461 ttgattcata actaatgtaa tgttaagttt aaattgttta gaatgatttt aaaagaatat
    11521 tcaaggaggt ttcatcaatg gaaaaaatca aagttgtcat tgtaggtgca tctcatggag
    11581 ggcatcaatc gatcttggaa ctattgacac gatacggtga aaatgtagat atcacgctat
    11641 ttgaagcagg agactatatt tccttcatgt catgtggtat ggagctgtat ttagaagaca
    11701 aggtaacaga tgtaaatgat gtacgtaatt tcagaccaga aaactttccg caatccaatg
    11761 ttcatatttt aaataatcac gaagtaaaaa cgatcgatgc cgataaaaaa acagtaacgg
    11821 ttactagcgc atcagataac gaaacaaaag aatatcctta tgacaaattg attttgagtt
    11881 ctggtgtcaa accaaacaat ctgccagtac caggagcaga tctagaaaat gtctacttga
    11941 tgcgtggata caattgggca accaaaatca aagaaaaatt aaatgatccg gctattaaaa
    12001 aaatcgctgt cgtaggtgcg ggttacattg ggatcgaagc agcagaagca agccgaaaag
    12061 ctgggaaaga agtcgtattg cttgatgtga tcgatagacc tttaggcact tatttagatg
    12121 ctgagatgac agatatttta gaacaacacc taaatgaaaa cggtattgaa gttttgacaa
    12181 atgcaaaaat cgaagctttt actggtaacg gaaaagttga ggcaatcaaa acaagtgaaa
    12241 aagaaatccc agcagatcta gtcattcaag ctgccggtgt gaaggcaaat acagaatggt
    12301 taaaagggat cgtcgactta gatgaacgtg gctggatcca aacaaatgaa tacttgcaaa
    12361 cgaatcttcc agatgtgtat gcagtaggag atgctacact tgcttattct atcccagcac
    12421 gcaaaaaaat gccgatcgct ttagcgactg ttgcacgtag agaagcacgt tatgtagtaa
    12481 aacatctttt tgaagaagta ccaaacaaac cgttcggcgg agtcgtaggt tcctctgcat
    12541 taagtgtctt tgactatcat tttgcagcaa gcggattgaa tagctttaca gcagcaaaag
    12601 caggagtaga tgtacgagtg tcttattatg aagatacgtt acgaccaaaa tatgtaccag
    12661 aagaacaagg aaatccaaaa gtgtccatcc aattattctc ggatccaatg acccatcaat
    12721 tgctaggagg agcagtatta tctacctatg atgttacagg tcaaggaaat gtattggcac
    12781 tagcgatcca aaacaaactg actttagaag aactagcaga agctgacttc ttcttccagc
    12841 caggctttga ccgacaatgg agcatgttga atctagccgc tcaacaagcg ttaggagaag
    12901 aaccatttgt agaataagaa aacgaaatat ttgaaaagag gttgtgaaaa agctgccttg
    12961 catcaagtaa taagaacagc caagtaaaaa cagcttctta tgtttttaac ttggctggac
    13021 ttattaccgc agatgcaagc ttttgaacac cgtttatttt caaaaaaggg actgtgacac
    13081 gatttgtgta ccgaccccca aaagttagac caaaaaatct aacttttgga ggtcggtatt
    13141 ttttatggtt aaatatactt ttgaacttaa attaaagatc gttcatgatt atttggatgg
    13201 caaaggcgat tggaccgtaa aaatccagat caagagattg aagcggaaat gcttaaaatt
    13261 cgggagaagc acaaggatta tggctgttta cggatgacca atgaactaag aaaccgcggt
    13321 ttctctatca ataaaaagaa agttcagcgc ttgatcaaga agctaggaat aaaagtaacg
    13381 gcatacacgc gtaaatcacg tcgctacaat tcttatcgag gaaaagt
//
LOCUS       DAPBAF010000066        12410 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.067, whole genome shotgun sequence.
ACCESSION   DAPBAF010000066 DAPBAF010000000
VERSION     DAPBAF010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12410)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12410)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12410
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.067"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(17..1246)
                     /gene="hflX"
                     /locus_tag="RD451_002492"
     CDS             complement(17..1246)
                     /gene="hflX"
                     /locus_tag="RD451_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HDT7567706.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
     gene            complement(1248..2165)
                     /gene="miaA"
                     /locus_tag="RD451_002493"
     CDS             complement(1248..2165)
                     /gene="miaA"
                     /locus_tag="RD451_002493"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HDT7567707.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            complement(2169..2906)
                     /locus_tag="RD451_002494"
     CDS             complement(2169..2906)
                     /locus_tag="RD451_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HDT7567708.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            complement(2997..3524)
                     /locus_tag="RD451_002495"
     CDS             complement(2997..3524)
                     /locus_tag="RD451_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567709.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            3704..4297
                     /gene="clpP"
                     /locus_tag="RD451_002496"
     CDS             3704..4297
                     /gene="clpP"
                     /locus_tag="RD451_002496"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HDT7567710.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            complement(4401..4886)
                     /locus_tag="RD451_002497"
     CDS             complement(4401..4886)
                     /locus_tag="RD451_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HDT7567711.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(5039..5236)
                     /locus_tag="RD451_002498"
     CDS             complement(5039..5236)
                     /locus_tag="RD451_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567712.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            complement(5331..7091)
                     /gene="efrB"
                     /locus_tag="RD451_002499"
     CDS             complement(5331..7091)
                     /gene="efrB"
                     /locus_tag="RD451_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HDT7567713.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            complement(7088..8818)
                     /gene="efrA"
                     /locus_tag="RD451_002500"
     CDS             complement(7088..8818)
                     /gene="efrA"
                     /locus_tag="RD451_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HDT7567714.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            9211..9423
                     /locus_tag="RD451_002501"
     CDS             9211..9423
                     /locus_tag="RD451_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HDT7567715.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            9425..11104
                     /locus_tag="RD451_002502"
     CDS             9425..11104
                     /locus_tag="RD451_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HDT7567716.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
     gene            complement(11358..11558)
                     /locus_tag="RD451_002503"
     CDS             complement(11358..11558)
                     /locus_tag="RD451_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDT7567717.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
     gene            complement(11708..11869)
                     /locus_tag="RD451_002504"
                     /pseudo
     CDS             complement(11708..11869)
                     /locus_tag="RD451_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein"
     gene            complement(12249..12322)
                     /locus_tag="RD451_002505"
     tRNA            complement(12249..12322)
                     /locus_tag="RD451_002505"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12286..12288),aa:Ile,seq:cat)
BASE COUNT         3622 a         2672 c         2156 g         3960 t
ORIGIN      
        1 ttaaaaaaat aaaattttat tggttttttc ttaaccattt tgaattggtt tttgcaaacc
       61 ctttaacttc atattcgttt gtttcttcca tgtacgcttc gtccaaaacc attgtttgtc
      121 ttctcaactc gcttaatttc tgtccttcgt tgcttggcac agaaagtgta taaggggtca
      181 ttagttccat cagctgacgt ttgattgctt cgatcaacgc catcttacct tctttcgtct
      241 gagtagaaat caatacattt gggaatagcg taggcgtgaa catcgctggg tcgatctggt
      301 ctgccttatt gtaaacagtc agtatcggca tttctttcat attcagttca tccatcaatt
      361 ttaagacagt ctgctcctgt aaaatacgat ctggagaact agcatcgact acatgtagca
      421 aaagatccat attttgactt tcttctaatg tagaatggaa agcatcgatc agttgcgtag
      481 gcaggtcttg gatgaacccg acggtatccg ttacagtaat ctcaaatcct tcagcaaaac
      541 gccatctctt agtcaatgga tctaacgttg caaacaattg atctttcgaa taagtatccg
      601 cttgtgtcaa tagattcaag atagttgact tcccggcatt cgtgtagcca ataagtccaa
      661 tctgaaaaat ctcgctattt tttctttttt ggcgattgcg ctctcgatga gcttctactt
      721 ctttcaattc tttcttaaca gcaaaaattt tattccgtat atgtcggcgg tctgtttcta
      781 actttgtttc acctggccct cttgttccga tcccaccgcc aagacgagat aatgttttcc
      841 cttgccctac taaacgaggc agcaggtatt ctaactgagc aagttcaacc tgcagcttcc
      901 cttctttcga acgagcacgc atcgcaaaaa tatctaagat aagctgcacg cgatcaatta
      961 ccggaagacc aacagcatcg gtaatcagtt ggctctgtct cggagttagc tcatgattaa
     1021 agatgatcaa atccgcttca tgcgcatccg cttgttgaac taattcttgt aatttccctt
     1081 taccgataat cgtttgccga tccacttgtg gtctcttttg tgtaattgtg aatacgactt
     1141 ctcctgatgc ggtattcgtc agctgaacta gctcttccat tgactctgaa aagtaacgct
     1201 ggtttgcttc ggtttctacc cctacgatga tcactttttc ttccatttta ttccgcctcc
     1261 agccattttt tgattgtttg ctcaatctga cttttttgat ttggctcact tataagatca
     1321 aaccactgtg catccaaacg gttacgaaac cacgtcaact gacgtttcgc gtatcttctc
     1381 gaatgtagtt tgacttgttc tgttgcttct tccaatgttt ctttcccttc aaaataaggg
     1441 aaaaattctt tatatccaat accttgactg gcctggactt ctccaagctc atacacctta
     1501 cgcgcttctg ctactaaacc ttctgctagc atcaaatcga ctctttgatt gattcgttca
     1561 taaagaatac tacgcttcgt atctaatcca atcatgaggt aatcatacaa ttgctttggc
     1621 tcttctttag gtgccgtgat actatgtcct gtcgtctcta aaacttccag agctcttatc
     1681 actttgcgtt gattgttcca gtggattttc tcagcagctg ccgggtcttt ttctttcaac
     1741 tgattccata atgcttggga accaattgtt tcagctaacg tttcatactt ttttctaatc
     1801 tcaggattcg cttcttctgt cgctcctaac tgataatcat atagaaggga ttggatatag
     1861 agacccgtac caccagctat gataggtagg tgccctcggt tcgcaatctc ggtaatcaat
     1921 tgtcgacctg aatgctgaaa atcagcggct gagtaacgtt gagtaggttc gatcacatca
     1981 atcaaatgat gcggaacatt attcatctct tcttctttga tttttgctgt accgatatcc
     2041 agatttttat agatttgcaa tgaatcacca ctgatgatct ctcctccaaa tagttgtgcg
     2101 agttccacac ttagcgctgt tttaccgact gctgtcggac cgacgatcac taatactttt
     2161 tccatatttt acctactttt cgttgattgt ttccaccgaa gagctttctc cggaaaatca
     2221 gttattattc catctatttt gagttcttga catttggcca tttcttcttc atcgttaatc
     2281 gtccatgcac gaattgcttt tggaaaatca gctgcctgga ctggatgttc gaacaaccaa
     2341 gtattttttg gatgtactcc ttctatataa ggggtttctg ctgctagttg gatcttttta
     2401 tcagaagtac tcatcaataa gtccagctgt atctccggtt ccagtaatgc gattttttcc
     2461 aaagaatcca aatgaaagct gcaatatgca tgttgaaaag gccaatctct actttttaat
     2521 gtttcggcta atttttcttc gataccggga tattcatact gatcagtttt aatttcaatc
     2581 attagcatcc ctcggtaatt tttttggagg agcagtccta acacttctct caattcagga
     2641 actttagctg ctggaaattc tttgctgaat ttgccccctg cattcaattt tttgagttct
     2701 tccaatgttt tttctcgaat cagcccttta ccgttagtcg tccggtccac ttcttcgtcg
     2761 tgcataacga tcaaataacc atctttgctt agatggacat ctagttcgat accatctgca
     2821 cctactcgta cagcttctgc aaatgcagga agcgtatttt ctgggtgggt gccgctgctt
     2881 ccgcgatggg catagatttg taacatcttt cttcactccg ttcagttcta ttgtatcatt
     2941 aagaaaaaaa gaaagcatta ccacgctctc atgtgcaacg gcaatgcttc aaaatatcag
     3001 ctccaaacat catctttcga gaagaaacca atcggctggc gcgtcatagt cttcaactga
     3061 gctttttttt cattgatcat ttcagtcaga ctatccgtaa aattctctaa aatcacgcgt
     3121 ccgcctttat aagcatatcc accaatcttc attgtttcat ctggagataa aatcactttt
     3181 cgatgggaga tattcttaaa tagctcgtct aaaatataat ttggcagata aaaactattt
     3241 tgcgctgaaa atgattggag atacgcaaaa tcgtcaatcg tgatataaca atcatcaaat
     3301 gcatcaaagc tgacatattc ttccatcagc gttgtccgtt tttgcaagat ctcgttgatc
     3361 tttttattta attgattcag cgtctcgatt tctttgactt tcaattccaa ttcacgtcta
     3421 cgctgttctt tattttccaa gtgacgcatt tgcagtatca tgccgatata gacaactaca
     3481 gcacctgtca gcactccgat aaggccagta ataccaacta tcaatctgtt gttcctcctt
     3541 gttttgtttc tctgcttatc ataccataaa gcgggtttat gcgactaatt tgcctaagtt
     3601 ttttatttga ccttttttga ccaaaaatgt atactacatt ttaggtatta gaaactaaat
     3661 tatggtacac tatttctaaa cgaaatcaag gaggaactct attatgaatt taattcctac
     3721 agtcattgaa caatcttcac gaggtgaaag agcttacgat atctactcac gtttattgaa
     3781 agaccgtatc atcatgttaa gcggccaagt aacagatgat cttgctaatt cgatcatcgc
     3841 ccaattgctt ttcttagacg ctcaagattc tgaaaaagat atctatcttt atatcaattc
     3901 tcctggtggt tcagttacag caggtatggc tatttacgac acaatgaact ttgtcaaagc
     3961 agatgtccaa acaattgtta tgggtatggc tgcttcaatg ggaagcttct tgctgacagc
     4021 tggtacaaaa ggtaaacgat ttgctttacc aaatgctgag atcatgatcc atcaacctct
     4081 tggcggcgct caagggcaag caactgaaat cgaaattgcg gcacgccata ttttgcaaac
     4141 acgcgaacgc ttaaacaaaa ttttagctga acgcactgga caaccgcttg aagtgattga
     4201 aaaagataca gatcgtgaca actatatgac agctgaacaa gcaaaagcat atggattgat
     4261 cgatgaagtc atggaaaaca gttcttcatt aaattaatct gtttcaaagg aagctttttt
     4321 aagctctctt atctaaacca aataaaaaag gatggtcaac tcaaactgac catccttttt
     4381 tattttatgg atgctactgc ctatctttgc tccttgaatt ttccttgcgc atgcatccga
     4441 cctatctcga cataatgctg gatgttttct ttgttttttt gtatttcttc ttttgtcaaa
     4501 ggacggatca ctttagctgg gcgaccaaaa gccaagacat taggaggaat aacttttcct
     4561 tctgttacta atgatccagc accaatcaaa ctattctcac caataaccgc atgattcaat
     4621 atcgtggtcc ccatcccgat cagcgcccct ttttcgattg tacagccatg tagcatgcac
     4681 tgatgtccta ccgtcacatt ctccgcaata tctacaggtg catcatgatc gacatggatg
     4741 attgtaccat cttggatatt cgttctttgt cctattttta tccaattact gtccccgcgt
     4801 aaaacagctt gataccagat cgtcacatct tctgacaatg tcacatcacc aatcactgtg
     4861 gcatttgatg ctataaaccg ttccatattt atttttctcc tttcattttt tgtagaaact
     4921 aatcctattg aataaaggta tcatagcata tatttatttc ataagaaaaa aaacaggtaa
     4981 aacctgctca ggccagatgt ctatttacag tatctggtaa ctgacgtttt acctgttttt
     5041 attgtacatc tatattttct tctattactt tttttaaaat taattcgtac acttctattt
     5101 gtgctgccaa gcgttcgatt tgaaactcat tttcaaaaaa atcagctgaa tcaaaaggct
     5161 tcgtctgaca gacgtgcgtt aaacgatcaa cttctctttt ggcttcagta attttttcat
     5221 ttaaaaactg ttccatctcc gtgtcctcac ttttcttgat aactttactt taccattatc
     5281 aagaatagag aacaaaaaat aagttttaaa ctgttttatt cttatatgac ttattctgct
     5341 tcctcagcaa attggctgtt atacagtttt tcataaaatc caccttgtgc caataaactc
     5401 tcatgcgttc ctttttcaat gatctgacct tgatccatca ctagaatcag atctgcatca
     5461 cggattgtcg ataaacggtg agcgatgacg aaacttgtcc gtccctccat cacgcgatcc
     5521 attgcttttt gaatcaacgc ttctaaacgg gtgtctactg aacttgttgc ttcatctaaa
     5581 atcaagattt taggatcgga gaccactgct cgggcaatcg tcagcaactg tttttgtcct
     5641 aaagacacat tgtctccctc agaattgatg gccatatcat atccatctgg catcgttcgg
     5701 ataaaatgat ctacgtttgc tgttttcgca gcatcaacta cttcataatc tgtcgcatca
     5761 agctttccga agcggatatt atctgcaatc gttccttgat aaagccatgc atcttgcaag
     5821 accataccaa atagcgaacg cacatcactg cgactcattg atttggtgtc gattccatca
     5881 atccttattg ctcctttgtc tacgtcataa aaacgcatca atagattgat caatgtcgtc
     5941 ttgccggcac cggtcggacc gaccacagct acggtttgac cagctttcac ttcaaaattc
     6001 aaatcttgga ttaatggttt cttcggatca tatgcaaaat cgacatgatc gaatgtcaca
     6061 tctcctaaaa tcgtttctgg cagtgaagca tctactttgt tttctttttc ttctggctca
     6121 tctaaaatct cgaatacacg tttcgttgcc gctgatgcac tttgcaaaac tgaagacaat
     6181 tgtgtcacgt tccccattgg ctgactgatt tgccaaatat attggatgaa tgcttgtagt
     6241 tgaccgacaa cgatcgcccc agtaataaca taaaagcttc ctagaacagc cataccaata
     6301 taagtagcat aggcagttaa ttgaactaga ggcatcatca agccagaaat gaatgctgca
     6361 cgaaacccaa agtatttcaa gctgtgatta acttttttga atccttccaa tgtttctttt
     6421 tcgcgtccat atactttcaa tacactaaaa cctgtcatat tttcttggac gtagccgttt
     6481 agctcaccaa gagaattctg catgctttga aaatatttct gcgaagcatt gatcactcgt
     6541 tttgagatcc agatcgatgt tggaatcatg atcatagaga tcagcgccat catcggctgg
     6601 atataaaaca tcattgctgc agccaacgta attcccaata tcgcatttac gataccaata
     6661 aaagcttgtt gtaaagcacc gctgactgca tctacatcat tcgtcacacg agacaaaata
     6721 tttccttgct ggtttttatc gaaatatgaa accggaagac gattgatttt ttcttctatg
     6781 tctcttctca aatcatgcat ggcactttga acgacatttg tcatcaaaac accagaaagt
     6841 aattgcgaaa tacaataccc tattccaaca actgtgatcc aaatgagaca tttgaatata
     6901 taagaaaaat tgattgattc gccattggca atattacggc tgatttctgt agtaggaagt
     6961 cctgtaacat atggcaaagc cacgttgaaa gccactgtca gaactgtaaa taggatcact
     7021 aaaagaaaag tctcacgata cggtctgata tatcgagcta aacgttttaa ggaagaaaag
     7081 gtttttttca tgctaattcc tcctttgata attgagaagc ggcaatatca taataaatcg
     7141 ggcatttttc caacaactcc cgatgcgtcc ccataccgac gacttctcct tcatttaata
     7201 cgatgatctt atctgcatgc atgatcgttc ccacacgttg tgctacgatc aatacagtag
     7261 attctgtcgt ttcttttttc agacgagcac gtaacttcgc atccgtttga taatctaatg
     7321 cagaaaagct gtcatcaaaa atatagattt ccggacggcg tatgatggct ctggctattg
     7381 ccaatcgttg tttttgtcca cctgaaaaat tggaaccacc ttctgataaa tgttcattaa
     7441 atccatctgg ttttcgagaa atgaattctg aagcttgagc aatctcagct gcacgttcca
     7501 tttcttcttg cgtagcatct tctttcccgt atcgcaaatt atctgcaatc gttccagtaa
     7561 atagcagcgc tttttgcgga ataaacccaa tcttatctcg caacttgctt agccgataat
     7621 ctctcacgtc tactccatcg atcaagatct ttccttcact cacatcataa aagcgaggga
     7681 tcaattggat caacgtagat tttccgctac cggtacttcc aataaaagca acggtctctc
     7741 ctggagaggc tgtaaaactg acatttcgta tcactggctc ttgcgaatgg cctggataag
     7801 caaatgttac attttgaaat tcgatatacc ctttagtttt tgtatcagat ataccatttg
     7861 gatcttctac aatcgaaggt ttggcatcta gggcttcttg gatacgtcca gctgaaacag
     7921 ctgctcttgg atacatcatg aacacactag caaataacat gaatgagaac aaggcatgga
     7981 atatatactc gataaacgca atcaaatctc ctacacgaag ctcgcctgca tcgatttgca
     8041 ctgccccgct ccagatgatc aataccatta cgatattaaa taagaaataa aaacccggtt
     8101 gtgcaacagc catcaaacgg aataagcttt ttgaactaga agcataattc tcattgacta
     8161 cagcaaaacg tttttcttca aacttttcat tgacgaatgc acgaatcaca cgcaatcctg
     8221 aaagattttc ccgcaagata ctgttgattt tatctaagtt tttttgttgc tttttagata
     8281 acggttcaga caccttagca atcgctacga ctgccaataa tagtaaaggt aatgcaccta
     8341 ctacatacaa actgagtgtc acacttgtac gcatgaccat gtacaaactg acaatgaaca
     8401 tcattggtgc cataaaaccg atacgtaaaa tattttgcag gaacaacatg atctgataag
     8461 catcgtttgt tgtacgagtg atcaatgaag atacgcctag attttcgtat tcctgatgcg
     8521 aataactttg gatcttttcg aacaaatcat ctcgaatatc tgctacgata ttagtcgtaa
     8581 tcctcgaacc aaaataacct aacaagatat tcaaaataat accgattaca gtaataacga
     8641 tcataaatat cccttgttgc ttcacataat caaaatcatc attgcggatt cctacatcga
     8701 tcatacgtgc taaaatcgta ggaagtccta attcaatcaa aataaaacca aatacgcata
     8761 tgaaattgaa aaacaagaat ttcttataac gcatggtata atgccacatt agtttcactt
     8821 tctcatctcc ttttaatctt ttgttacatt ttcattacta aaaatgatag cacaacgagc
     8881 ctattaatag aacacttctc tcataaaaaa gtcattatga ttatagcggg atgataaaca
     8941 ttgatttttt ctttcaatct agttgatttc tatacttatt tgctgtttta tgctagaata
     9001 acaattaatt gttgtatatt ttttatacag aaggtacggt tgaaaaaata tccgaacaga
     9061 taagcaaaaa cgaggcttgt ctctttgact cgaatccagt attctagtca aagcatatga
     9121 aaaaccaggt ggcttgtccc ctcgttttgt gttgtctaaa aaaatcaact agctaaatca
     9181 ctgctttacg cagataaagg agacaaaaca atgatctata aagtttatta tcaagaaaca
     9241 aaagtacgca accctaaacg ggaagaaaca aaatctcttt acattgaggc aaaaagcgat
     9301 gtagacgctc gccaacgtgt ggaagaaaat accccataca atattgaatt cgttcaactt
     9361 ctagaaggaa gtcatctaga gtacgaaaaa gaaaatgctg atttctcatt agtggagttt
     9421 taatatgaaa ctttccatca aaaataacga gacaggcgtc tttgctattg gtggattagg
     9481 tgaaatcggg aaaaatacgt atggggtaca attccaagat gaaatcattt tgattgatgc
     9541 cgggatcaaa ttcccggaag acgatttact tggaattgac tatgtcattc ccgactacag
     9601 ctacatcata caaaacttac acaaagtaaa agccttggtg attactcacg ggcacgaaga
     9661 ccacatcggc ggaataccct acttgctgaa acaagcaaat attcctatct atgctggtcc
     9721 tctcgcatta gcgttgatca caaacaaatt agatgagcat ggcttgcttc gagatgcaga
     9781 gctccatgag atcaatgaag atacgatcat ccgttttaga aagacttctg tcagcttttt
     9841 cagaacgacc catagtatcc cagatgcatt agggatcgtg gtgaaaacac cttctggaaa
     9901 tatcgtagcg actggagact tcaaattcga tttcactcct gttggcgaac cagcaaactt
     9961 gcataaaatg gctcgtatcg gggaagaagg agtcttgtgc cttttatctg atagtacaaa
    10021 tgctgagatt ccaacattta ctaaatcaga aaaaacgatt gggcattcta ttttgaagat
    10081 cttttcaaaa atcgaaggac gtatcatttt tgccagcttt gcttctaaca tcttccgttt
    10141 gcagcaagca gcagatgccg ctgtggcaac tggtcgtaaa atcgctgttt tcggacgaag
    10201 catggaaaat gccatcgtca acggtcaacg tttaggatat atcaaagttc cagacggcac
    10261 atttgtagat gcacacgaaa tcaatcgctt gcctgccaat gaaacgatga tcctatgtac
    10321 aggttctcaa ggagaagcga tggccgcgtt gagccgcatc gcgaatggta ctcaccgtca
    10381 aatccaaatc cagccagacg atacagtgat cttttcaagt tcacctattc ctggtaatac
    10441 aacaagtgtc aatcatttga tcaatttgct gtctgaagct ggtgcagaag tgattcacgg
    10501 aaaaatcaat aacatccata cttccggtca cggtggacaa gaagaacaaa aattaatgct
    10561 tcgtttgatg aagccaaaat attttattcc tgtccacgga gaattccgca tgttgaaagt
    10621 acatgcttct ctagcacaag atgtaggtgt tcctgcagaa aactgcttca tcatggaaaa
    10681 tggcgatgtt ttagcgttaa ctagcgattc tgcgcgtcct gctgggcatt ttgtggctgg
    10741 agatgtgtat atcgatggta gcgggatcgg tgatattggt aatgtcgttt tacgtgaccg
    10801 tcacctgctt tcagaagaag gtcttgtatt agctgtcgcg acagtggata tcaagaaaaa
    10861 agaaatcttg gctggtccag atattctctc tcgtggattt gtctacatgc gagaatcagg
    10921 agaaatgatc aatgaagctc agcgaatctt attccacgct ttaagagaat gtttgaatgg
    10981 acctgactgt tcagaatata aattgaaaga agcgatgact ggcgcgcttc agcctttctt
    11041 attcgaacgt acagaaagac atccaatgat tttgccaatg gtaatgacac cagatgaaga
    11101 ataaataaga ggttatgaaa tcagcacctt gtcctgaata taagagaaaa caaatgaaaa
    11161 acatgagaag ccatttttgt ttgttcttat tccttgatac aaggtggctc tttcatagcc
    11221 tcttaaattt atttactttt tcatacaaaa aaatacctgc cacaagagaa attgtctctt
    11281 gtggcaggta tttttgttac tcgctttgtt ctctcgtaaa aattgatgtc taccatcaat
    11341 ttgatttaca gataaaatta agcttttaca acgtttgcag cttgtgggcc gcggtctgat
    11401 tcttcaacgt cgaaagtcac tgcttgacct tcttctaatg ttttgaatcc gtcaccttgg
    11461 atagctgaga agtgaacgaa tacgtcgctt ccatcttcac gtgagataaa tccaaatcct
    11521 ttttcagcgt tgaaccattt tactgttccg ttttccataa taatatcctc ctcgtgccaa
    11581 aagcactaat ttaaattgta acattgctcg tgtacgatag aggtgcaaca gatgtttcaa
    11641 cttctattcc caaacaaaat tacaatataa ttgtacactt gcttcatttt ttttgcaaga
    11701 aagcaactta cttctcttcc atcattcctt cttctctcaa actaaaatat cgtttgcgtc
    11761 cgatgatcaa gtggtccagt acagtgatcc ccatcatttc tccacacttt tgtatccttt
    11821 tggtaaaatt catatcctgc tgcgatggaa taacattacc agaaggataa tataggttag
    11881 tacacgtata aaaatatctt ttatattgac acaatttatt taacaagtat aataataatt
    11941 gaaagtgaat ttaaacaaat atacaccata aacacaacgt acctgcgaat acgttgtgtt
    12001 tttttctttt tcaaaaaaag acgcttaccg ctgcgaaaca gtaagcgcca ttgtcggctc
    12061 taatgtttat ctagccaatg actaaataat gccaaagtta aaccaattaa caatggcaag
    12121 agcacgtgct ccaaagtgaa ttcaaacaaa tcatacacct cctcccacga aaatctctgt
    12181 ggaagcgacg agccgacatt ttattatacc attattgaat tttatttttt atcaaataga
    12241 ttaaattatg taccctgtag gactcgaacc tacgaccgga cggttatgag ccgtctgctc
    12301 tgaccaacta agctaagggt actggttgtt gccacataaa gccataaaca atcaaccagt
    12361 agaaggtgtg gcaacaatcc tgttatcgca taattttgga gtgtgattag
//
LOCUS       DAPBAF010000067        11806 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.068, whole genome shotgun sequence.
ACCESSION   DAPBAF010000067 DAPBAF010000000
VERSION     DAPBAF010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11806)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11806)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11806
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.068"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            508..1071
                     /locus_tag="RD451_002506"
     CDS             508..1071
                     /locus_tag="RD451_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567718.1"
                     /translation="MLYIKKGIIVISFFKEYLEIINFRLKTKKESVIILVYFQGGNLM
                     IKKLFLLSILTLAMAGCSDSGLATELITKSTEATTEELKCGNDHSDYRGLNRRCMGIL
                     GRSNCKHRCSNRRRCRRSNRKIKRKIKRSNLCCASYTDVEDAVLLNHVRRCSFMSREV
                     GDEPKLEYAFSFAREDEDNPKTYDILA"
     gene            complement(1132..1497)
                     /locus_tag="RD451_002507"
     CDS             complement(1132..1497)
                     /locus_tag="RD451_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567719.1"
                     /translation="MRLWHEKLISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFH
                     YSPYRLFQYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHD
                     EVYLAECLANLEQKGIYLT"
     gene            complement(1573..1818)
                     /locus_tag="RD451_002508"
     CDS             complement(1573..1818)
                     /locus_tag="RD451_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7567720.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            complement(1888..2142)
                     /locus_tag="RD451_002509"
     CDS             complement(1888..2142)
                     /locus_tag="RD451_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567721.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            complement(2306..2629)
                     /locus_tag="RD451_002510"
     CDS             complement(2306..2629)
                     /locus_tag="RD451_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567722.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
     gene            2816..2889
                     /locus_tag="RD451_002511"
     tRNA            2816..2889
                     /locus_tag="RD451_002511"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2850..2852,aa:Ile,seq:cat)
     gene            complement(3274..3771)
                     /locus_tag="RD451_002512"
     CDS             complement(3274..3771)
                     /locus_tag="RD451_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HDT7567723.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(3811..4620)
                     /locus_tag="RD451_002513"
     CDS             complement(3811..4620)
                     /locus_tag="RD451_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDT7567724.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIAMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            4954..5811
                     /locus_tag="RD451_002514"
     CDS             4954..5811
                     /locus_tag="RD451_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HDT7567725.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            5804..6706
                     /locus_tag="RD451_002515"
     CDS             5804..6706
                     /locus_tag="RD451_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HDT7567726.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            6739..7089
                     /locus_tag="RD451_002516"
     CDS             6739..7089
                     /locus_tag="RD451_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HDT7567727.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            7138..8061
                     /locus_tag="RD451_002517"
     CDS             7138..8061
                     /locus_tag="RD451_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HDT7567728.1"
                     /translation="MDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPDDIFVG
                     TEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLITCIDR
                     KTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAARKTTEN
                     EELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQRQTEK
                     MIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTGGLPGK
                     SSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            8139..9032
                     /locus_tag="RD451_002518"
     CDS             8139..9032
                     /locus_tag="RD451_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDT7567729.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKVAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            9070..9633
                     /gene="amaP"
                     /locus_tag="RD451_002519"
     CDS             9070..9633
                     /gene="amaP"
                     /locus_tag="RD451_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HDT7567730.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            9647..9835
                     /locus_tag="RD451_002520"
     CDS             9647..9835
                     /locus_tag="RD451_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HDT7567731.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            9848..10750
                     /locus_tag="RD451_002521"
     CDS             9848..10750
                     /locus_tag="RD451_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HDT7567732.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            10782..11024
                     /locus_tag="RD451_002522"
     CDS             10782..11024
                     /locus_tag="RD451_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HDT7567733.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(11280..11651)
                     /locus_tag="RD451_002523"
     CDS             complement(11280..11651)
                     /locus_tag="RD451_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567734.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
BASE COUNT         4184 a         1990 c         2237 g         3395 t
ORIGIN      
        1 tcattggtcg ttgaatgggc tgaatagtag tgtataaaac aattttgtgg agcgtgaagc
       61 ttttatggta gaggaaaata cgaataaagt gatgttgata aaaagattcc tatcttgaat
      121 atgaatcgag atgtcttgaa aatgaatgag tttgaccaat cattatccta tcgaaattta
      181 cagtttcgtt cgattggtct gtcaattaat gaaaaagtaa aaaagaatat gttctaggaa
      241 gagggcggca catctaaatt tttaagtaac ggacagttca aatatcaagc attgaaagag
      301 gctatcctac tgtttgaagg aatacgaata tataaaaacg acaaagagga aaaagtagtt
      361 cattaaatcc cttcaagtga tgaaagaatg agatctaata aaacctgatc tttcatctgt
      421 ttttttaata acgtaataat ttttttattt tttgtgcttt cgccgttatt gtagagtgat
      481 ttagcattct tatttttaaa aataactgtg ttatatatta aaaaaggcat aatagttata
      541 agctttttta aagaatattt agaaattatt aattttcgtc tgaaaacaaa aaaagaaagc
      601 gttattattt tagtctattt tcaggggggg aaccttatga taaaaaaact atttttacta
      661 tcaatattaa cgctagcaat ggcaggttgt tctgactctg gcttagcaac tgaactgatc
      721 acaaaatcaa ctgaagccac gacagaggag ttaaaatgtg gaaacgatca cagtgactac
      781 agaggcttaa atcgacgatg catgggaata ttaggcagaa gcaattgtaa gcatcgatgt
      841 agtaatcgaa gaaggtgtag aagaagcaac agaaaaatca aaagaaagat caaaagaagc
      901 aatctgtgct gtgcatcgta tacagacgtc gaagatgcgg tacttttaaa ccacgtcagg
      961 agatgttcat ttatgtctag ggaagttggc gatgaaccaa aactagagta cgcttttagt
     1021 tttgcacgtg aggatgaaga taaccctaaa acttacgaca ttttagcttg atctaagatg
     1081 gttaaagctt tttaatgaag taagaggaga tagaaggctt ttctagttat attaggtaag
     1141 ataaattcct ttttgctcca aatttgctaa acattctgct agataaactt catcgtgttc
     1201 cggataaatc ggcacgttgc gctctacagt aggtaaatca aaaaatgctt cgcatgattt
     1261 gccacgatac ataggatttt tccactctgg tgctgggctg taaccacgtt tttccatttc
     1321 atccatgaca agctgatgat attggaataa tctataagga gaatagtgaa aaacataatc
     1381 cacagtagca tgtttctttc cccagccatt tcctcttaat gcacagcatt cccgatgttg
     1441 tcctaaaagc tgttgacgag gaagctttga aatcaatttt tcatgccata atcgcataga
     1501 aatgtctcct ttatatatag attgttaacc ttagacgtta aatgaaaaaa ccagcaccaa
     1561 ggctggaaaa aatcacttca gtttgcttgc tgtttctgag cgaccaatta ggtaatcaac
     1621 ggaaatatcg taaaagtcag cgatatagat taattcaatg atgcttggaa tttcttctcc
     1681 ttcttcgtac ttacgatatt tgaataaagg aatacttaac gcgctagaaa cagctacttg
     1741 agataaagat cggccagttc ttaagaaatt cagacgacaa cgtaaagtat ccagtaaaat
     1801 agcttcttcg atactcattt aatcaccttt cattatagta gaatagttat aatgactata
     1861 gaaagctaca catgcaatca atagtactca atgtttttta tttaaacgta tcaaataaag
     1921 aatgacgatc aataaagaca aaaccagtcc tgataattct tctataaaaa cactatcggg
     1981 ttcaaagtag ttgtaattaa aaactttcca cataaagtag atagccggaa gagtcaaaat
     2041 agctaaataa aaccgttctt tgttccaatt cataagataa acaatacttg cgaccagtgc
     2101 gaccgcaggc acccaaaaca aaactctcac caacgtaatc atgtaacgga ctcctcaacg
     2161 attcatataa taaaagataa catgttattg catacatcac aaatgaaatg ctaggaaaat
     2221 aaaagaagaa tagatcaatg aaaaatgaaa aagcagaaca gttttctgct gataagcagg
     2281 aactgttccg ctgaatgtgt cttatctatc gagaaaaaat caatggattg atatctaagt
     2341 aattcaatac atataaaaag aggacgatcg cattcactaa aaaggaaaga atgatgatcc
     2401 catagcgaat ggaaacatat ttaacaaata cttttgtttg aatacgggca tatctttttc
     2461 ctttatagct gagcatcatg acaagaagca aaagggtaat cacaccttga aaaatcattc
     2521 caataaacag aattcctgag gtttgataat ttaattggag aaaataagct gctgccgcaa
     2581 ctaaatcgaa taaaatcgca ataaatggca aaataatcac tcctaacatt gagaataaat
     2641 aaaagaataa cattttttct aaaataagca aataaaaatt aaagtaacaa aatagttatg
     2701 acacaagtaa aagaaataag aataacaata ttattttact tatattttga aacttgtgag
     2761 agtttgtcat tcgtgctata gttgaaaagt aacaaaaata aattttattt atgatgtacc
     2821 tttagctcag ttggttagag cagacggctc ataaccgtcc ggtcgtaggt tcgagtccta
     2881 caaggtacat aagaggttgt gaaaaagctg ccctgcatca agtaataaga acagccaagt
     2941 aaaaacagct tcttatgttt ttacttggct gttcttatta ctgcagatgc aagcttttga
     3001 ataccgttta aggaagaggt tgtgaaatca gcgttttgac ctgagtatta gcttaacaaa
     3061 cggaaaaata gttcctcata ttttgccgtt tgttaagcta ataccgaggg tcagctgatt
     3121 gaacaccatt taagaaagag gtcgtgagcc tgccgtttca ctctgtgtca taaaaaagcc
     3181 aatctacttt gatagaaaaa gcacgtagga ctaaaacagt tctgcgtgct ttttttattg
     3241 tgtgttaaat atcgtaaatg aagatagata tttttatgat tcgacgatag agacgttgaa
     3301 atctttcaac agctctaaag cggattctcc gtgttttcta ctggagacta acattggatc
     3361 aacaaaaaag tctgcttcag gaaaagcact ctgcaggcct atcagattag agagtacaca
     3421 caagtttgtt tcaatcccga ctacttcgat ctctttttgt tcttctttgc tttcaaataa
     3481 agtttcctgg atttcagcta aagtttcagg tggaatcgta aagtaatact ttttaatcac
     3541 tcgttcattt tcttgtggag aaagaagagg gatcaattgc aaatcttctc gttcttcttc
     3601 tttgtccttc agttcaactg gtatatcccg tgtgaagaga atatattcat tattttggcg
     3661 tgctttagct aatctttgag caatacgttc tgccaattga tctgactctg gaatataaaa
     3721 ttcgctgttt ggatcaagaa tatgattttg catatcaata ataactaaca ttttctttcc
     3781 tcctacattc atatcgtcat tttattcttt ttaatagaag ttttttaaaa tataagcaac
     3841 accagcttct tcattcgtca gtgttacttg gtttgcaatt tcttttactt gtcgctgtgc
     3901 attccccatc gcaatactca acccgctgta attcaacata gcaatgtcgt tttcttgatc
     3961 gccaaaagcc atgatgtcac tcgattcgat tccaaggtaa tccgccagaa aaacaagtga
     4021 atgagcttta gtgatacctg taggcgtgat ttctaagaaa tgcggatcag agaatactga
     4081 ttggatacca tctgcttgca gatctctttg tagcttctgt agtttttctt cactcttatc
     4141 tgttaatgct aatttaagat agctaagaga aggatcttcc aacatattta aaatttgatc
     4201 aaaagaatgg ttctgtaaat tgaaatgttc ataataaggg tcatctttga ctagatttga
     4261 ttcatcgaat gtcagctgat catcttgggt ttctcggcta gcaatgatgg atattttcgc
     4321 ttcttgagca tagaagaagg cttttctcag tgtatcgcta tctatttttg aacgtctgag
     4381 aactttcgcc atttttccat ccttcatttc agcaatcagt gaaccattgg aagaaatcaa
     4441 atagccaccg attcctaatt cggaaaaaat atctttagca gaaatgctgt tccttccggt
     4501 agcgacggtt acgattccgc cattttcatc aaatttccga agtgcttgga tattttcttc
     4561 tggtatcttt ccatttcgat caagcaaggt accgtctaaa tcaatcgctg ctagtttcat
     4621 tttatcttcc tactttcttt ttacatatct attttcctgt taccttaaga ttaaatgaga
     4681 atttaaaaaa atgaaactaa cttgctttgt cattatgaat tttttcaaaa aacaatctta
     4741 agaaaaaggt ggctatatat agtagttttt ggtcaatacc tttgaataaa aagccatgaa
     4801 aaacgaatag ttagcgctta ccgatgcgtt ttgtgataaa aaaattttaa aatattcaat
     4861 gaaaacaaag catatatttt gctttaaaac caaatgagga atattctaga tgtagaacag
     4921 gttagaaaaa gattagaaaa aggagtgatt ttgatggaga agagatacgg cgtagttcct
     4981 gtggtaactg cttcagacga aaattatgct ccttacttga gcgtgatgat cgcaactgca
     5041 ttagaaaatt gcaataaaac aagacgcata aaattttatg tgattgacga tggtctatca
     5101 gaatatagta aagaaggatt ggaagaaacg gtaaataaat attcaagtaa tgcaagtatc
     5161 caattcctga cagtggaaaa agatatctac gaagacttcc tagtcagtga ccatatcaca
     5221 actaccgctt acttaagaat ttctttacca aacttattag ctaaagagga ttataagaaa
     5281 gtcctttact tagattcaga tgtgttagta ctagacgata tcgtaaaact atatgatgag
     5341 ccgttaaatg gaaaaacaat cggcgctatt atcgatccag gccaagtgaa agctttggaa
     5401 agattaggaa tcgattccga tgacttgtac ttcaattcag gagtgatggt gattgacatt
     5461 gatcaatgga ataaaaaaga aattacagaa aaaactatcc attacctcag tgaaaatggc
     5521 gatcgaatca tctatcacga ccaagatgct ttgaatgctg tactttatga agattgggaa
     5581 caacttcatc caaaatggaa catgcagact tcgctgattt ttgaacgtca tccagcacca
     5641 aatgaaaaat atgaacgtca gtataaagaa ggaaatgaaa aaccttcgat cgttcacttt
     5701 acaggacatg ataaaccttg gaatacgttg aaagatcatc cgtataccaa tttatactta
     5761 aaaaaattag cacacagtac tctaacgaaa gtaggcgaga tcaatgaata aaaaagaaat
     5821 agcagtagtc gcaagttgta acacaaaatt cgtaccacat ttagctgcat tatttgtctc
     5881 agtattagat aattgcaacc cgtctaaatt tgttcggttc tatgtgattg acgatgatat
     5941 cgattttgaa agtaaacagc ttttacgctt ctcagtgaaa aacgcacgaa tgaactcaga
     6001 tgtggaattc ttgaaaatca ataaagaatt ctttacaaat gtggtaatca gcgatcgtat
     6061 tccagaaaca gcttattatc gtattgcgat tccggaattg ttccgcggca cagaagttga
     6121 acgtatctta tatatggatt gcgacatgat cgctttacaa gatatctcta aattatggcg
     6181 tcttgacttc ggtgattcaa tcgtagcagc tgttgaagac gctgggttcc atcaacgact
     6241 ggaaaaaatg aaaatttcag ctaaatcaat gcgttatttc aactcaggtt tgatgctgat
     6301 caatgtgaaa aaatggttag atgaaaatat tacgcaaaaa gtattagatt tcatcgaaca
     6361 taatccagaa aaattacgat tccatgacca agatgcatta aatgctatct tacatgaccg
     6421 ttggttacca cttcatccgc gttggaatgc acaaggctat atcatggcaa aagcaaaaaa
     6481 acatccaaca gcagcaggtg aacgtgaata cgaagaaact cgcaacaatc cttacattat
     6541 ccatttttca ggacatgtga aaccgtggag caaggatttt gaagggccaa cgaagaaata
     6601 ttacgaaaaa tatgcaggga tgacggcttt ccgttgtgta gctaaattcc ctaaatatcc
     6661 aaaatatgca aaagttcaac caaaaacaga tgtagttgtt aaataataga agacaacaac
     6721 tgaagagggg gagtaggaat ggaaattaca atgtctaaaa atgcagtaga gacgttaatt
     6781 gaaaaggttg gggaaaatac aaaaatcgca ctcgcgctta tcaatgattc cgatccattt
     6841 ctaagggaca aaggtgcttt tgcaaaaggc agcttttttc aaatcattcc ttttgtttcg
     6901 gaatttggag aatatgcgac taaaatcgag catccattat tggacatcta tacatctaaa
     6961 ttagagcaaa attatttcgg taaacgattg aacatggact tcaacaaaca gcttgacagc
     7021 ttttcattag aaaatgaaat cgcagtactc gattataata tcaaattaaa gaactgcttc
     7081 ttcagctaat agtttcgaga aagtccaaaa aggaggtata cattgagata ctactttgtg
     7141 gatgaagaaa agaatgtaat agaaacagat gaaaaaaaat ataattggct cgtacttgat
     7201 agtgcaaagc ccgaagagat tgagcaagca atcgaagaat tcgagcttcc tgatgatatt
     7261 ttcgtaggaa ccgaatatcc ggaagaagtt tctcggatgg agcgccttta tgagacgaaa
     7321 ctagagcatc cattttcttt ggtagtgatt aatctagatc agtcagataa tcgtatcgaa
     7381 aaaaaattaa cgccaatatc ttttgtactt tccgataatc tcttgattac ttgtatcgat
     7441 agaaaaaccg aatttgtgga tcggctgctg acaaagcatg gaaatcattt aaactcgttt
     7501 gaaaagatca tcacgtatac attattagat atttacaccc attacgtgaa agaactaaga
     7561 gagatgaaaa agcgaattga cgctttggat aaagcagctc gtaaaacaac ggaaaatgaa
     7621 gaactgtata aacaggcaga tcttgaaaga gacatcgtat atatcgatca taccttaaga
     7681 gatcaacggg aaacaatgga tcaattatgg aattctgaaa ctttcatcaa acgtttagac
     7741 gatgaacagc tactctatga tgtccatttg agacagcgac aaacagaaaa aatgatcgag
     7801 atctatcgag atttattaga gagtattggt gatctattca acgggatgat ggacaataat
     7861 ctaaatcata tcatgaaata tctagattca gctgcattaa tcatttccgt tccggcgttg
     7921 ttcgcaggga tttggggaat gaatacagga ggattaccgg gtaaaagttc tgctctaggc
     7981 tttatactcg tagtctttgg ctctttgata gcagcagtag ttttaggtta ccatttatac
     8041 cggaaagatt atacaaatta aagaatctat ttaaaacagg tatcaaacaa agaaatttgt
     8101 tttggcaata caatttaaaa actaggagga atacagcaat gacagaacca aaattaatcg
     8161 acccgcgaaa cttgtaccat acggagaaat ttcctaaaca agatcaggat acaccagctt
     8221 tacagcagaa tatgattcct gttcctgatt gtggagaaga atcctatgaa ggcaataatc
     8281 aactagaaaa ccgccgtgta ctaatcactg gtggagattc agggatcggt cgtgcagcag
     8341 cgattgcatt tgctagagaa ggggcagata tcgctcttca attcttccca ggagaagaaa
     8401 aagatgcaga ggaagtagca aaatacgtga aagttgcagg acgtaagatt gtcttactac
     8461 cttttgatct tcgtgacgaa caagcaccta aagaaatcat agataaagcc gtgagtgaac
     8521 ttggcgggct agatacgatg gtactaaacg caggacagca aatttcttgt cagtctattg
     8581 ctgagttacc acttgagcaa gtcaaagaca catttatgat aaacatcatc gctatgtttg
     8641 ctttagtgaa agaagctgtt ccgcatatcc cagcaggagg agcaatcgta acaacaactt
     8701 ctgttcaagc attcaatcca agcgaacatt tattagatta cgcagcaaca aaagcttcaa
     8761 tcgctaactt tacgatcggt ttagcaaaac agcttgcacc taaaggaatc cgtgtaaatg
     8821 gtgtagcacc tggtccaatc tggacaccat tacaactaga cgaaggacaa ccttctgatt
     8881 cgatccctga atttggtcag caaagtttac tagaacgtgc aggtcagcca ggagaattag
     8941 caccagttta tgttttctta gcatcgaata aagcaagtta tgttacagcc caaatttacg
     9001 gagtaactgg tggagaagcg atcaacttat aagaagttga tcgtttcacc cctatgagga
     9061 ggtgcgaaaa tgaataaagg tgtaaaaacg atcggagtga tcggaacatt acttttgcta
     9121 tctgtgcttt tgtttgcgat actattaagt gcaacctatc cattgccttt tcagctagag
     9181 aagtttcgat tcttttccat cactaattca tacgtgcaac aatatgtatt ttggcttgcc
     9241 gttgcatttg ctattttgac aattatcacg ttacttgttt tcctgtttta tccaaaaaca
     9301 atcggaaact ttctactgaa acatggtgat ggggagttga cgttggataa aaaagcaatt
     9361 gaaggaatgg ttcgttctca cttgcatgaa gatgaattca tccattcacc aaaagtaaat
     9421 gtcaaagcaa cgaaaaacaa gatcgccgtc aatgtaaaag gggagttgaa acgaacttca
     9481 gcactcattg gtaaaacagg aacattgatg aaagaaatcg aaaatgaagt acaacacata
     9541 ttgggaacaa aagagccagt gaaagtatcg gtgaaataca caggctttga agaaccagct
     9601 aaacgaagca atgaccgcaa acgagtagaa taggggggga ccaaaaatga aagaactatt
     9661 ttcgacatac aagctcccta tcatctttgg ggtacttgga ttgatattag ccgttttatg
     9721 gatcaccgtg ggctttttca agaccttatt gatcttgatc atggcagcga tcggcgtcgc
     9781 tatcggtttt tatctgaaac aaacgaaaat cttagatcac tattttaaat cttaggagga
     9841 aacatccatg aataacaata acaaaaataa taacaataaa atgaacaacc aaaaaccagt
     9901 gtctgcacat ccagacccaa cgacaccaaa ccaatcaaat ggtgtgaacg atgaaaagaa
     9961 caaaacagca ccagtatctg cacatccaga tccagtagtc cctaacgttc aacaaggagt
    10021 agaagagaag aaacatgatg cagaaaagca tgcacctcat catccaggaa ctccagaatc
    10081 taaagttcca gaacaacatg atgcaatcga tccttctaaa cctgtggaag agcaaaaaca
    10141 tccttctgac catgcgaaag cacaagaaaa acttagttct gaccacacaa acggacaagg
    10201 aaaacttggt tctgatcata caaataacca aggaaagcat gattctgaac aggaagattc
    10261 aatgcgcggt gagctgaatt atgaagataa agttgtgcaa aaaatcatcg gaatcgcaat
    10321 tgaacaagta gacggtttat tatctgcaaa cggtggtttc ttctctaatg tggcaggaaa
    10381 acttgtgaat acagataatg taacggctgg gatcgaaaca gaagtcggta aaaaacaagt
    10441 agcagttgat atggatgtca ttgtggaata tggcaaagat atcgaaaaaa tctttgaaga
    10501 aatgcaagaa gtaatcggca aagaagtaaa aaatatgaca catttagaag tgatcgaagt
    10561 caacgctaac gtagtggaca tcaaaacaaa agaagaattt gaaaaagatc aagaaacggt
    10621 gcaagacaaa gtaactgacg cagcgaaaaa aaccggtgaa tttgcttcga atcaaacaga
    10681 taaagtaaaa tcagcagctg gaagcggcgc acaaaaagta aaagaaaata cagaaccacg
    10741 ggttcagtaa taaggaagta aaacattagg aggaacgaaa catgggattt atttggtcac
    10801 ttatcgtcgg aggaattatc ggagcaattg caggagcaat cacgaataaa ggttcttcga
    10861 tggggattat tgcaaatgtc gtagcaggtt tagttggatc agcacttggt caagcattat
    10921 taggttcttg gggaccaagt attgcaggaa tggcaatcgt gccatcattg attggtgcca
    10981 tcattttagt actaatcgta tcattctttg ctcgaaaact gtaaaaagac ttttaaaaag
    11041 aggtcgtgaa aaagctgttc ttcatcaagt aataagaaca gccaaacaaa aatagcttct
    11101 catatttttc atttggttgg gcatattatc gaagatgcaa gcttttgaac actgtttata
    11161 cggaataaga ggctgtgaca agacttttgt cacagcctct tatttatgcg ggcaaattcc
    11221 caattagatt tttaaaagtt tttccttaaa tgtgtcttta ttgatacaga gaagcttctt
    11281 taataaaaca atgcctccct aaattttctt gagataggaa aggtgaacat acaaaataat
    11341 acgaccactt tgaaaaccca gatgatccac aaatggatcg tatgatactg atgaagtaaa
    11401 aagcaatgga tcagaaactc aaagagattg aaaaagacaa ggaagaaata atatctcttt
    11461 tttactcttg tctgttttag ccaataatag ctcgtaaagt aatctagaca aacaaataga
    11521 agtaaacaaa gtttcgtaag agcagcaatc gtatcatgtt gctctgctag acgattgacg
    11581 agcaggaaaa atgttggtaa tggaatatag atcacgagta atgaaagaaa aaagtaaaca
    11641 ataaatggca tactattcct cctaattgtg tgagttcgcc ctcattttaa aataacgata
    11701 tttgtttgtg aagctttttc gtgtcgtaac aaatgttatc taatgtattt ttaaataaat
    11761 aatcattatt atcaaaataa tgtcagactg tagacaaagt ccattt
//
LOCUS       DAPBAF010000068        11752 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.069, whole genome shotgun sequence.
ACCESSION   DAPBAF010000068 DAPBAF010000000
VERSION     DAPBAF010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11752)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11752)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11752
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.069"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            416..622
                     /locus_tag="RD451_002524"
     CDS             416..622
                     /locus_tag="RD451_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HDT7567735.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(824..1825)
                     /locus_tag="RD451_002525"
     CDS             complement(824..1825)
                     /locus_tag="RD451_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDT7567736.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(1830..3743)
                     /locus_tag="RD451_002526"
     CDS             complement(1830..3743)
                     /locus_tag="RD451_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HDT7567737.1"
                     /translation="MNSLRTKQVLKGALVILFAVSTSVPQWTVYGESISSESESREVE
                     TTETTDAGNETKSSTSQTETNTETTVETSVTSTDQETTATTDNQQTEEATATKMSNDE
                     SSSAKVSDKENGTENDDIGKGENFNGKEYLNYFGKQMTEILNGPTEDIKSKLIELLVT
                     ELAVNDYGVDKEIIKHLIATYLLYDIAFAKNSVLMSMLGGTDDGTTPTENTGFYPNTK
                     QLHQTVLNKQDGKMMDVYAYYVDQGSDKTVMIHGGFRGNWNNGIVTEEYNDFYKAGYN
                     LLFVDSRATGNSGGDYVTYGQYESDDVLYWINQEVRERPSQKILLYGGSMGAATMMSV
                     LAKDIPVNVKGIIENCGFASIDEQLRFTYSQTVAPALPDAIKNQLDIIGDQEHEDLFM
                     GLLKQYYFDQEMHLDTKAALPTIGMSDSLPKLIIHGTADDVVPVSNAQKLYELSGGYK
                     DLLLVEGAGHGKAQEVDHAAYTKHVTDFLKVVFHDQINVKYVDENNKSLLKDQDEIQL
                     YGAYGENYMTEQKTFEGYELANVEGPTEGIFNETIPTIIFYYKKIPVAPPKKQDPTEN
                     ADNKGKNEPREDQSSDDTQPIQMTVKVQKKTDAKKRMLPKTGEKKHSLLIYSGGFLSV
                     STIITWIWRRKRG"
     gene            complement(3911..4417)
                     /locus_tag="RD451_002527"
     CDS             complement(3911..4417)
                     /locus_tag="RD451_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HDT7567738.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            4577..5017
                     /locus_tag="RD451_002528"
     CDS             4577..5017
                     /locus_tag="RD451_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HDT7567739.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            complement(5043..6200)
                     /locus_tag="RD451_002529"
     CDS             complement(5043..6200)
                     /locus_tag="RD451_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7567740.1"
                     /translation="MRTIQRKLRELNTILKNYHLSCSLKKGNPIEGEEYRIRYFFHLM
                     YWQSFDENHSDILSSIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSI
                     TYVPEEMNKFVHPLITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYL
                     EEDLLDTPDKVQESWGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGT
                     KKKVDAFGKSAEDRDFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCML
                     VRDIFIKHEQPVIFYIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYP
                     IDKKAYDQTNTQIFYWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(6203..6559)
                     /locus_tag="RD451_002530"
     CDS             complement(6203..6559)
                     /locus_tag="RD451_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567741.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            complement(6857..7831)
                     /gene="sgrA"
                     /locus_tag="RD451_002531"
     CDS             complement(6857..7831)
                     /gene="sgrA"
                     /locus_tag="RD451_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HDT7567742.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSESSTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            complement(8027..8866)
                     /locus_tag="RD451_002532"
     CDS             complement(8027..8866)
                     /locus_tag="RD451_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDT7567743.1"
                     /translation="MIRIIRLIGSVLIVLVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            9051..9938
                     /locus_tag="RD451_002533"
     CDS             9051..9938
                     /locus_tag="RD451_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HDT7567744.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEEAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
     gene            complement(10532..11227)
                     /locus_tag="RD451_002534"
     CDS             complement(10532..11227)
                     /locus_tag="RD451_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HDT7567745.1"
                     /translation="MEIMLDTANTKSIYSCQQFLNLTGVTTNPTILKKEGASNFFSHM
                     KEIKKIIGQIPIHIQTIGRTEEEMIEDARVIIEELGKDTFIKVPVNQAGLQAIKKLKK
                     EGYLITGTAIYTELQGYLAINNGADYIAPYYNRMQNQGIDAMKVIDSLRTEIERTQRP
                     TKILAASFKNCEQVTTAIRSGAHAITLGKELLDQVLEMPSIDKAVRGFQEDWVQTFQA
                     ETIGELKKVADYF"
     gene            complement(11211..11609)
                     /locus_tag="RD451_002535"
     CDS             complement(11211..11609)
                     /locus_tag="RD451_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HDT7567746.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
BASE COUNT         3505 a         2324 c         1757 g         4166 t
ORIGIN      
        1 tattattttt gtttcttatt ttctaaaaaa ttaaaaaaaa ttttggtgaa ttaagtattt
       61 ccttgataac actggctttt ggcctcattt taggttatca tttgtaattt tatttcacag
      121 ttgatatgat tgttatgtaa aataaaaaag tttaggatac atcgaatttt tggggaaatt
      181 cttttggggg tatcctaaat cttttctatt atattcccat attttctatt attggtctag
      241 acgtatgatg gtaaactttg tacctatctg attgctgaat cattaattgc ttatcattag
      301 ccatctttgt ttcaagttcg ctagatgatc attttattca catcctaaca aacttgtcac
      361 atttatagat tcttaatcta tttatcatac aattataaaa aaggaggtgc tgcttatgaa
      421 agctatccat atttctttgc tttttttcgc tagtgcattg attttatttg ctattcatct
      481 ttgttcccag ccttatatca ataacaacgg aatattagtg gaaccagcat tcttttgctt
      541 accactcggc tttttgtccc ttcttgcctc cgcaggcttc ggatttgttg ctttttttaa
      601 acgatcaaaa caacaaatct gacttataaa atttacgtaa aagagatcgt gacaataatc
      661 gtgtgatatt cccaaatttc gaataaaagg tgccccttgc catctctaac tcctcagtca
      721 caagttacaa tattcataaa ccatgaaaag cttgtttatt gaaattgctc cttgtgactt
      781 ggagctaagt gacagattac aacctctttt gcatcataag actttactcc ttgaaaaaca
      841 ttactaactt ttgatatgtt tcttgcgctt gtttattgct gaaatcaaac tgatattcat
      901 ggttcaaaac agcatttttc tccgcataat ctacttttgt gactttcacc cccgctttct
      961 caaatacaga agttacttct tccatttgtt tcgtaaacgt atttgtattt ccatccgtta
     1021 agaatgtgtt ttgcgtccaa cgatccgcat gtctgaccaa ggctaaactt ttgaccttct
     1081 ctgattgttc aaagtcctta ttatcaaagt aagcccatcc acatttttca taaagaaagc
     1141 tagagatttt atcacttact tgagtaagtg cagaaggatc caacagacca gacaaagaaa
     1201 taaacttcgt aatctgcttg ttctccaaag tcggatcaag atgatcagct tttttaattt
     1261 cttcattttg aagtgctaac aaatattctc cactaatttg tgcacctgcc gaatttccac
     1321 caatcgaaat attcgaccaa tctgcttgat cttttatctc ttttttagct gcttgaatgg
     1381 cttcgttcaa ttggataact ggtgtaggat gttttgcttc cggtgatcgt tcataatcta
     1441 tatttacgat gatttgctgc gtgtctgaac atagatattc caaataatca cgacaatcat
     1501 ttttatcccc tcctacatat gcgcctccat gcatccagaa aagaatcggt aattttttct
     1561 tttccacttt cggtgtgtag atatccatat tattattttt gtactttgaa ggataggata
     1621 tttctttttt tatatcgatt tgttcgattt tttgctggaa atcatctggt cgggcatata
     1681 cttgttcttt ttcacttgtg tcaaattgtt ttctaacaag caagctaatc ggctttggtg
     1741 tgatttgatt aatcaaaaat acagtgacta aaataactac gatgataact ggtactgcaa
     1801 tcactattcg cttgaaccat ttcattcatt taccctctct ttcttcgcca aatccatgtg
     1861 ataatcgtgc taacagataa aaatccacct gaataaatga gaagcgaatg tttcttttct
     1921 ccagttttcg gcaacattct tttttttgca tctgtctttt tttgtacttt cactgtcatc
     1981 tgaatcggtt gcgtatcatc acttgattga tcctctcgag gttcattctt tcccttattg
     2041 tctgcattct ctgtcggatc ttgctttttt ggtggagcta ctgggatttt tttgtaatag
     2101 aaaataatag ttggtatcgt ctcattaaaa atcccttcag tcggtccttc aacatttgct
     2161 aattcgtatc cttcgaatgt cttttgctct gtcatataat tttctccata agctccgtaa
     2221 agctggattt cgtcctggtc tttgagtaga cttttattgt tttcatccac atactttacg
     2281 tttatctgat catggaacac tactttcaaa aagtccgtta catgtttcgt gtaggcagca
     2341 tggtcaactt cctgtgcctt tccatgccct gctccttcta ctaataaaag atctttatac
     2401 cctcctgata actcatataa tttttgcgcg ttagacacag gtactacatc atctgctgtt
     2461 ccatggataa tcaatttagg caatgaatct gacattccaa tcgtaggtag agcagctttt
     2521 gtatccaaat gcatctcctg atcaaaatag tattgtttca aaaggcccat aaataaatct
     2581 tcatgctctt gatccccaat gatgtctaac tgatttttta tggcatccgg tagtgcgggg
     2641 gctactgtct ggctgtacgt aaaacgtagt tgttcatcaa ttgatgcaaa tccgcaattt
     2701 tcaataattc ctttgacatt gacaggaata tctttcgcta atacagacat catcgtagct
     2761 gctcccatcg aaccaccata aagtaaaatc ttttgagatg gccgctctcg aacttcttga
     2821 tttatccagt aaaggacgtc atctgactca tattgtccat aggtcacata atcgcctccg
     2881 ctattaccag tcgctctgga atcaacaaat aataaattat acccggcctt ataaaaatca
     2941 ttgtattctt ctgtaacgat cccgttattc caattccctc gaaatccgcc atggatcatg
     3001 actgttttat ctgaaccttg atcgacataa tatgcatata catccatcat tttgccatct
     3061 tgtttgttta gtacagtttg atgaagttgt tttgtatttg gatagaagcc tgtgttttct
     3121 gtaggcgttg tcccatcatc tgtacctcca agcatcgaca tcaacacact gttttttgca
     3181 aaagcgatat cgtacaatag ataagtagca atcagatgtt tgataatctc tttatctaca
     3241 ccataatcat taacagcaag ctcagtgact aataactcta ttaattttga cttgatgtct
     3301 tctgttggtc cattaagtat ttctgtcatc tgtttaccga agtaattcaa atattcttta
     3361 ccattgaaat tttcaccttt accgatatca tcattttctg tcccattctc tttgtcactt
     3421 actttagcag aagaggattc gtcgtttgac atttttgtag ctgttgcttc ttctgtttgt
     3481 tggttatctg tggtagcggt cgtttcttga tctgtgctag taacagatgt ctcaaccgtt
     3541 gtttcagtat ttgtttctgt ttgtgaagta ctcgatttcg tttcatttcc agcatcagta
     3601 gtttctgtgg tttctacctc ccgagattcc gattcggaag aaatgctctc tccatatact
     3661 gtccattgcg ggacgcttgt acttacagca aataagatga ccaacgctcc ctttaatact
     3721 tgttttgttc tcaagctatt cactcctttt tatgtttcta ggagaattat atgtaaacgc
     3781 aaacattttt tatacaaaaa ataaatggtt tatcccataa aaatagaaca ggattatttt
     3841 ctcattttac gtaataaagc agaatggata aaccagtatc cattctgctt tttttaaacg
     3901 aagaaacaac ttattgctcc aaaaatgtca gaaatcgttt atcccaaatt ttctcgtaaa
     3961 aagcgattgt ttcctttgct ttcataaaag gattatcata agttgtcgtt gctcctctac
     4021 acatcataag ctggtatcct aatccatgag caaacttcac agtcgtatct atacaatact
     4081 ctgcttgtgc cccacataat tcgatcgaat gacagtccaa ttcagttaat aaaacactca
     4141 aattagtctt ataaaatgaa ttcgcatggg tttttctcac aaaataactg tgctcaggaa
     4201 tagataattc cgacaatagc tcccatggtt ttgtttgtgg cactaattga gcatcttcgt
     4261 gttgaacgaa aataactggt ttcccaatcg tttcgtatgt tttgattctt ttattcacta
     4321 atgctgtcac tgtttctaat tcgtgtatcg gcgaagaatc aaaacatacc cctttttgta
     4381 aatcgatcac tactattgcg tcggctgtgt ttgacatact tgtgccttct ttcttttttc
     4441 ttgatttaat agtatttctt atctagctag ttccattata cgtgacaaca ttttcttatt
     4501 ttacacctct aaatggcact tttcgactat ttcttcatgt tattatttca taaatactta
     4561 gctattggag gaatgtatga tgattaaatt gtatacaggt tctggctgct cgtcttcaag
     4621 acgcgcaaaa cgttggctta tcgtccatga tataccgttt atcgaacaga acttaattcg
     4681 tcaaccacta accaaaaatg aatttatcca cttactaaaa ttgacaaaca acggcgtgac
     4741 cgaaatgctc tctactcatt ctattagtta taaaaatctt gttcacagaa tagatgaact
     4801 cagtttgagt gaactatata ttgagattcg tacatcccct tctttattga aaaaaccgat
     4861 tatctacgac caatctgcaa aacttttgac tggatttagc gaagataaaa tcaggatgtt
     4921 cctttctaaa actaaaagaa agcaagagct caacgaactc ttgctttctg gtcatcttgt
     4981 cgattttaaa gaaaataatc tttttgcaat gtcttaattt tggcataaac aatctgcttt
     5041 tcttaattaa cgaaatccaa tttttccaat atggatctat ttttctcatt cctgattttt
     5101 atgatttcag ctttcagacg cgcccaatca ttttttgtag gttgtccatt ccagtaaaat
     5161 atctgtgtat tcgtttgatc atatgccttt ttgtcgatag gataatcgct aatgacaata
     5221 tcaggtaact gatcagcgga tgcactatat tttattgggc gttcagtcat agataatatc
     5281 cttttctttg cccataattc ctgtgtttta ccatactttg attgaatata gaatatgaca
     5341 ggttgttcgt gttttataaa aatatccctg actaacatac agtattgaaa aatcaaccgt
     5401 ctgttctttt cataataagt attaagctct ggaattctgc gagctacccc actaaaaaac
     5461 tgttgcatga ttggatacat cactggaaat atatgctgaa aatctctgtc ttctgctgat
     5521 tttccaaaag catccacctt cttttttgtc ccaaaaaccc ttgaatacaa atggatcatt
     5581 gccaaattga catatagata atttttttct gaagttgtaa aacaaatctt gaagtttttt
     5641 tcaaaatttt ctacaataga cgattcaatc cagccccaac tttcttgtac tttatctgga
     5701 gtatccaaca aatcttcttc caaataggtg ttcattacac caaacataaa ataaaggtaa
     5761 gcttgctctg ttggagtgat gtgattcatc gaccagaagt ttgcttcaaa aaaaggctct
     5821 agtatgtaat gcgtaaactc ttcttttgtt atcaatggat gcacaaattt gttcatctct
     5881 tctgggacat acgtaatcga gtggccttgt ttcattcgtt gcaacgaaat tcttagtagg
     5941 ctgatccatt tctttctatc tatactacgc gtatatggcg catgtttcgc aaatttttct
     6001 aatagttgac gtttattttt tatacttgat aatatatcag aatgattttc gtcgaatgac
     6061 tgccaataca tcaagtgaaa aaagtatcgg atacggtatt cttctccttc tatcggatta
     6121 ccttttttca agctgcaaga taaatgatag tttttcaaaa tagtattaag ttctcttaat
     6181 tttctttgaa tcgtacgcaa acttatataa ttttttgact aagattttct aaggattgat
     6241 aagtaccttt gtaaagtgaa tccagtaaaa tataaccaat cgttccctct aaaagtatag
     6301 aataaacttt actcagtaaa aactgagaag aaaactcgac ttttatcatc ttgttttctg
     6361 aaagaaaaga taatttatat tctggatacc tttcgcaaaa cgattctgct tgttgaatca
     6421 ccgaattcat cttagccagg gtgtagttta gatctaaagc gatatccttc accacatata
     6481 atttctcgtc tctttcataa caatagttca aaaattgata tacttgcctt tcattgatat
     6541 caataaattc ttcaaacaaa gtacatactc ctttttatct attatttaga cttattccga
     6601 cagctacatg aataacgtac aaatagattc gttactgatt tttcagagat actaccatgc
     6661 gcagtgtgca ttgtcaatta ttcttgctct tattttccat ttgtgttcct gttatttcct
     6721 gtttctcaaa tatgttagta aacaaaaata gatctggcaa agctacaact tcgccaggca
     6781 atacagcact ctcgaatgaa atattcactc aaaaatctat cgttttattc aattttagat
     6841 ctgttgcttt tattctttat ttcactcgat ggaagagaga acgaaaatag cttgctccta
     6901 caatcaaaat gagtaacaca cccatccatg taattagctt gttcaaggtt ctactaccag
     6961 tttctggtaa atcgcttttt ctattatctg tttctttcgc tttttcttga tgatcaattc
     7021 cacgagaaac aaaatcaggc tgttttagca cactttttag gttgctccct gcatttctct
     7081 tttgttcctt agttggtatg ataggtacca aatcaagttc attatttact tttcctgtgc
     7141 tgctttcgct gctcgtgctt cctgtgctac tctcactact catgcttcct gtgctacttt
     7201 cactactcgt actctccgta ctgctttcgc tgctcgtgct tcctgtgcta ctttcactac
     7261 tcgtactctc cgtactgctt tcgctgctcg tgttttctgt gctactttca ctgctcgtac
     7321 tctctgtact gctttcaccg ctcgtgtttt ctgtactgct ttcactactt gtgctatccg
     7381 tactgcttgg cggtccaaca actgtccaac tgcttggttt caaattctcc gtgatcgtca
     7441 tctgtccatc ataaaaaaca atcaaatcaa ctttatcttt actcttgatc tcatcaatcg
     7501 atagttctgc agaaatcatt attgtatact caataccagc ggtccattgt acgtctttta
     7561 aataaacttc cccaataact ttttctgaac ttccattacc atcccaacca tatgttagaa
     7621 cagcatgtac atcactagca ttcacgcttt tgtttggttt gactggaata gtaatgactt
     7681 gttgtgtcat gtcataaaca atccgatcag ttttcacagt aaatgaaaga ttctcatttg
     7741 cccgttcatt tgcagaagta ctgattccaa tcattgctgc aattatactc agcccaagaa
     7801 taacaaataa tacggtcgct gttttcttca tttctatcac tctccatata attaccttct
     7861 atttgataaa ggaattatat aaaatgaaaa tgatgagaac acgacagtca gttgtgaaaa
     7921 tctaacaaaa gatgtcgtgt attcgcttga atttgtttac tttttcgttt aatcaatgac
     7981 agacttaaaa aagcaagacc gatatcagcc ttgctttctt catcttttat tgataaacag
     8041 cagtgtattt cttcatccgc tttgttttat atgcatagag taacaaacca acaatcaaga
     8101 ctaacaagaa taatgtagtt gatatagatg cttcagcccc aaagtttccc ccagtaatta
     8161 ttgtattttg cgattggatc agagtggaga aaaaaccttg ttcttgcgtt ccgctgactg
     8221 gtatacccaa aatagctcct tgtgtccaat tccaagtaat atgagcacca atagccgtaa
     8281 ataaacttcc tgtactgtag ataagtgcgc tgaaaaagca acctgctaaa aagatattga
     8341 aaactgccag aaatgtcatg ttaggattca atccgtgcaa aagagcaaat aatgcagcag
     8401 atccaatcat tgctattaac ggaccaaatc taagcatctg atgctgaaaa aagccacgga
     8461 ataaaagctc ttctgatgcc cccactgcaa taaataaaat aaaactcgtt atcagcggca
     8521 caatgtttgc gtttcctgaa tctaaccgat acgcccccgt caaatataat ggactagtaa
     8581 taagcagaaa cactccaatt ccaacaacga gacctcccgc taaatacccc cagtcttttc
     8641 ctcgaacaga aacaccataa tcttctattc tttttccttc gaccttacta gcaagaaata
     8701 aagctagtaa aaaaacagct aaatgtccga ccgtaccggc aattgctcca atccattcac
     8761 tatttccaat aaacatatcc gcaagtgcat tattgacaag aattcctaaa acaaaaccaa
     8821 ctaagactat taaaacagat ccaatcaacc gaataatcct gatcatcttt catccctcct
     8881 ttatattaag tttaacaacc cttttctttc ttgtctcgtg aaaactatgt aaatgttctc
     8941 catcatagag agaatagatt tttacgaact aagaatatct acagcaacct tacgaaaatg
     9001 aaagactgtc tccctaattc ttctgttaga ctgtttttaa taaggaaagg atgggaaatt
     9061 ttttgaaaaa acaactacta attatgtgcc tttcagcatg tgcaatttta ctattctcag
     9121 gttgtagcaa gtccaatgaa acgattgcaa cgtttaaagg tggaacactt acagttcagg
     9181 atttttatga taacccaaaa gttaaatcaa ataatcaaac actattaaaa aaaatgattg
     9241 tcttcaaagc atttgatgat gtatacggaa aagagatttc ttcaaaggaa gtaacaaaag
     9301 aatataatga acaaatcaaa aaactcggtc caaactacaa ggaacaatta aaagcagttg
     9361 gccaaacaga agagacatat aagaaactct ttaaacagat gctggctttc caatacggtt
     9421 tgaaagccaa tgtaaaatta acagataaag atctagacac tgcttggaaa gaattctatc
     9481 cagaagttag tacacagatc attctatttt cgactaaaga agaagcagat aaagcaaaaa
     9541 aagaagcaaa tgaaggagaa aatttctcca agcttgttca agcttatgga aaaaataaaa
     9601 cattaaagga aactgatgga aaaatgaatt ttgattcaac caatccagag attcctactg
     9661 aagtaaaaaa agcagcattt aaactaaaaa acggggaagt ttctgatatc attcctgtaa
     9721 cagatccaac gacttatcag caaagctatt atctagtaaa aatggtaaaa aaacaggata
     9781 aaggttctaa taaagacaaa tacaaatctg agctagaaaa aattgctacc gaagcaaaaa
     9841 ctcttgatac ggaattcatg gataaaacaa tccgtaaagt gatgaaaaaa gacaatgtaa
     9901 ctattaaaga tccttatgta aaaaatatat tcaaataaac aaatttgacc caattgggga
     9961 tgtggcaaaa tttgagaagt gatttttgga aattccttct tatttttgag gcaaaccact
    10021 tttgccacaa cttcatcggg gccttttttt atttgtacca aaacaaatca ctggatttgt
    10081 tacaatcatg aggatataat ttaaaaaagt tttttatttc tatcacatga atcaatgcgc
    10141 cattaagtag attctttcat gcttccctat tttttcactt gccgtatcgc ttcaaaaaca
    10201 actatcataa actcaaactc gactgaaaag ttattttaaa aaagactaaa aatatccctt
    10261 ctggacttgt tcttcttatt ctgttatact agagaaacac gaaagatatt tttatgcgac
    10321 acttttcatt tgtttttatg aaatttattc aaaactggcg taacttcaga gttacaagga
    10381 tgtattagag gttagggaat acatcgttta aatgagaaat aagtaatagt tagtaatagt
    10441 cacccaaact ttaaattaat gaatattgaa tcgtcagata gcctcctcga gttttcgaga
    10501 aggctatcgt ttattttatg gagaaattga ttcagaagta atcagcgacc ttttttagtt
    10561 caccaatcgt ttctgcttgg aaagtttgca cccaatcttc ttggaagccc ctcactgctt
    10621 tatcaatcga gggcatctct aatacttgat ctagtagctc tttacctaac gttatcgcat
    10681 gagctccaga tcgaatggct gtagtgactt gttcacaatt tttgaaacta gctgctaata
    10741 tttttgttgg tctttgcgta cgttcgatct cagtccgcaa cgaatcaatc actttcatag
    10801 catcaatgcc ttgattttgc atcctgttat aataaggtgc aatataatct gctccattat
    10861 taatagctaa atacccttgt aattctgtgt aaatagctgt accggtaatc aaataacctt
    10921 cttttttcaa ctttttgatc gcttgaaggc ctgcttgatt caccggcacc ttgataaacg
    10981 tatcttttcc cagttcttct atgataactc gagcatcctc tatcatttct tcttccgttc
    11041 ttcctattgt ctgaatatgg ataggaatct gtccgattat ttttttgatt tctttcatat
    11101 gcgagaagaa gtttgacgct ccttcttttt tcagaattgt aggatttgtt gttacgcctg
    11161 ttaaattcaa aaactgttga caagaataaa tactttttgt atttgctgta tcaagcatga
    11221 tttccatata gctttccccc attctgatcc tcttgatcga ttttaatgat tgtccccttt
    11281 cttaaatgcg gcatttcctt atcttctaca tacattgttc ctggaagttc cggctcatga
    11341 gatccatcaa attttatcgt gatatgtcct aattcattca aattagtttg gacaacatct
    11401 cctactgctg tgattacata catttgttta tcaaaacaga gcttcatatc acaagttatt
    11461 tcttttctta cctgattcaa ttcaatctta taacaataat ctgttaatgt ttccggtgct
    11521 tcatctccaa ataaaatcat tattttttct ttcctgaata cttctgcttc tataccaaca
    11581 tctgttacaa ccgtttcaaa gatcgtcatc tctgttcctc ctcgtaaaat atcatttgtc
    11641 taatagtttt tattcaaaat gtttctagat tataaaattt attgaataac acattcctaa
    11701 cggaatttgt ttcgatattg tgtgatttct cagagtacaa tggatgtatg ga
//
LOCUS       DAPBAF010000069        11579 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.070, whole genome shotgun sequence.
ACCESSION   DAPBAF010000069 DAPBAF010000000
VERSION     DAPBAF010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11579)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11579)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11579
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.070"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(366..1484)
                     /locus_tag="RD451_002536"
     CDS             complement(366..1484)
                     /locus_tag="RD451_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567747.1"
                     /translation="MAKKDKELLTQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            1955..3262
                     /locus_tag="RD451_002537"
     CDS             1955..3262
                     /locus_tag="RD451_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HDT7567748.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWGDKVSISDYAENLSIT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETDRLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAD
                     DKLGYLEDNNAPSTEIITDKTVEKANIFVIGWRRVAEFFGNLF"
     gene            3381..4580
                     /locus_tag="RD451_002538"
     CDS             3381..4580
                     /locus_tag="RD451_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HDT7567749.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYGSTWTFTVI
                     LTYFVVLEIFYSTFYFLIPLLFFSIFAFSYFTEKRRLLNGLLFNVLLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVLLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCVPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYRAQSRATLNPPILLMSGGQGADEKVPE
                     AIAMKQYAMEQGIPERDILVETNSTTTLENMLYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYARQAKLKANGIGAKTAFYYLPNAFLREYLAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(4607..5875)
                     /locus_tag="RD451_002539"
     CDS             complement(4607..5875)
                     /locus_tag="RD451_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HDT7567750.1"
                     /translation="MEKQLPSPVRILVYMLKWLVITAILGIFMGSLSAFFLNSLTVVT
                     DIRLSHPWLLCLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNTARLFRLDKSEREILIISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVCRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHVYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAALA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAVYFFMICLISFMCSGN
                     SGIYSAQQVAVKKGILFLPIVKRMKEKNKV"
     gene            complement(6038..6684)
                     /locus_tag="RD451_002540"
                     /pseudo
     CDS             complement(6038..6684)
                     /locus_tag="RD451_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="FusB/FusC family EF-G-binding protein"
     gene            complement(7092..7595)
                     /locus_tag="RD451_002541"
     CDS             complement(7092..7595)
                     /locus_tag="RD451_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HDT7567751.1"
                     /translation="MTEKWREDEEYMSYVEDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TELSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(7718..8482)
                     /locus_tag="RD451_002542"
     CDS             complement(7718..8482)
                     /locus_tag="RD451_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HDT7567752.1"
                     /translation="MKEIQSAKNPRIKELKKLHKKKYREEKEEYLLEGFHLIEEAASS
                     DAEIKELFVTQRGMKEWGDWLAANKEISTFLVSDEVMDAVSDLPTPQGILAVMALTAE
                     GTPDFSGGWLLLDNVQDPGNVGTMIRTADAFDMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLTEVISLMKDKGFTVYGTELNEEAHALDKVEKSDNFAIIMGNEGQGVSQ
                     EILSLTDQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            8590..8865
                     /locus_tag="RD451_002543"
     CDS             8590..8865
                     /locus_tag="RD451_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HDT7567753.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            9303..10253
                     /gene="yidC"
                     /locus_tag="RD451_002544"
     CDS             9303..10253
                     /gene="yidC"
                     /locus_tag="RD451_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HDT7567754.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVAIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVMMKPRLKAQVAEELKQNPPKQVVTPR
                     IDVTESAKPADSKQATKQIKQPKNSTNNKGRNAGKQQKRK"
     gene            complement(10432..10632)
                     /locus_tag="RD451_002545"
     CDS             complement(10432..10632)
                     /locus_tag="RD451_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567755.1"
                     /translation="MGGISALSFMENGVLCGRATWAKGVAPFVTEGEEKASSWMLEEG
                     KQNIKELSTLLEETATPVYVDR"
     gene            11437..>11579
                     /locus_tag="RD451_002546"
     CDS             11437..>11579
                     /locus_tag="RD451_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7567756.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQG"
BASE COUNT         3502 a         2425 c         2042 g         3610 t
ORIGIN      
        1 tttaaacggt gttccagaag tagcttcttc ggaaataagc cgaaatttca caaaaatttg
       61 agaaataatt tttgtcaatc tcttcttatt tcttgaagct gaccacttct gtcacaacct
      121 cttccttaaa cggtgttcaa aagcttgcat ctgcggtaat aagcccacca aacaaaaaat
      181 atgaagagct atttttgctt gctgttctta ttacttgatg cagaacagct ttttcacaac
      241 ctctcataca cggtgtttaa tcagctgacc ttcggtatta gctcaaaaaa cggaaaaata
      301 tgtgaaacta tttttccgtt tgtttctcta atactcaggt caaaacactg atttcacaac
      361 ctcttttaat aacgaagaat cgctgtcaga ctcttttcat ctggcgcatc tttttgatcc
      421 aaaataaaca ctttcccgcc attaatgatc acatcatctg ctaatgcatt cagcacttga
      481 cgccgatcat attctgtttc aggatcttca ccgaaaccat cagctaagtt tgacgtagcg
      541 ataaataaat gtgacacttt tccttctttc gcagctggaa cgatatcaac taactgatcg
      601 atgaatttct tatctaagag tttattgtat tcttttgatt cttgagctgc gagttcactt
      661 gacagcttct tcgccccttc ttcgatatct ctaaaggata gctgcgcagg agaagcagaa
      721 atcgcaacgt ctgcacaata atagggattt ttagcaattt ttttgaacat cgtctgattt
      781 tctggtaatg caaataaata aatcggccat tgttcaggat tttcgaaaga atccttcaag
      841 tacgtatcaa cagcttggta atagttgacc caatcgatct ctacttcttc atcttttgga
      901 tttacgccat ggaaagttac tccatctcgg gctccgcctc ctccattaga agagaagttc
      961 aaaccgccac ctgtcagttc agatcccaat gcagtaacga catcaaccgg tgccccttct
     1021 ggtagagata cttcttttac ttgtttgttg ctgacctcat acaatttcat ggagtcgcgg
     1081 ttcaatccca ataaataata agaatagttg aactgcccat ttttgataat agccagtaaa
     1141 taaggaagat cacttacata gtattgatcg tctaccggga tactcaaacg atggatatag
     1201 gtctggtcag cagttataat gaccgctaca ctcgtagttg cactacgcca aaacgaagga
     1261 tctcctaaca aattttcaat tttttcttgg aacggggacc agtcatgttc ggaatatttt
     1321 ttctcaaaac gtttctttgc ttctttcgca aaatttttga atttgatctg atctttttcc
     1381 acatcttgat gggcgacatg cgtattcagc atgatcgtga cgaatggtcc tttagcgcct
     1441 tctgaagtca attgtgtcaa taattcttta tccttttttg ccataaacgt acccctccta
     1501 aaaaaatcat tcctttgttt ctatctaaag tctaccacaa cactattttt ccatacaata
     1561 aaacgtatct aaaaaaataa aacggtttct acggttttaa atttagctat ttttttaagt
     1621 tatcttcata atttcctcaa ttatttagcc ccagtcttca actattcttc atgaaatgct
     1681 gataaactaa gaaaaagaat aaaagaggtg gatcttatgc atttgattat gattttcagt
     1741 ttattaagta ttatcagttt atttgctttc agcgcttccc gcttattaga tgcggaaaca
     1801 cagcctattc ctgtaaaagt acgtaaaaac gaccgttaaa cttccataac gcgcgttctt
     1861 atcctaaagt tttttcagaa acattgaaac tctctcccct ctctgataaa attttaattt
     1921 gtagcgaaac aaattaatta caaggagatc ggatatgtcc ataaaaaaaa cacgtctagt
     1981 cctattattg gctagtctca ttctttgcct tgcttctttt ctaccagctg ttgctgtgca
     2041 agctgaagat acgttcaaag taaatgcaaa agcagctttt gctgtagatg cgcaaagcgg
     2101 taagattctt tatgatcaag atggagaaaa aaccatgggg atcgcttcaa tcacaaaaat
     2161 catcggtctt tacatcgtcc ttgatcaagt aaaagaagga aaactgtcat ggggtgataa
     2221 agtttcgatt tcagattatg cagaaaattt gagtatcacc ccagatttat cgaatgttcc
     2281 tttgcataaa gaaaacacct acactgtcaa agaattattc gactctgcaa tcatccagtc
     2341 agccaatgct tcaatggtgg ccttggcaga aaaaatctct ggcagcgaag ctaaattcac
     2401 tgaacgaatg aaagaacaat tgaaagattg gggaatcaaa gatgcaacaa tcgttaatgc
     2461 atcaggattg aacaactctt atcttggcga aaaccgacca gaaggcactg gagaaaacga
     2521 cgaaaatcaa atgtctgctc aagatgtggc catcgttgcc cgccatttga tcttggattt
     2581 cccagaaata ctggatgtat caagtactac gacccaaatg tttggcgaaa atacgcaatc
     2641 accagtggaa atggtcaact ggaactggat gctcccagga ttcgttaatt acaaggaagg
     2701 cgtggacgga ttaaaaactg gtacgactga gcttgcaggt gcttgtttcg ttggtacgat
     2761 cactaaaaac gatcaacgga tcatcactgt cgtattgaat gcggacggcc atgcggaaaa
     2821 cccgagtgcc cgcttcaatg aaacagaccg tttgatggac tactgctatg acaattggtc
     2881 agaaaaagag ctcggaaaag ctaacgcaag tattcctagt ctaaaaacca ttgatgtaaa
     2941 agacggaaaa gaatcaacag ttcctgttgt gcttaaaagc cctgtaaaag tatgggtacg
     3001 aaacgatatg gatactggca aattaacgat cacgccaaca cttgacaaga agcaagtcac
     3061 tgacaatgag atccaagcac ctatggataa aggtacaaaa atcggtaccg ctacgatcac
     3121 cttggcagac gataaattag gctatttaga agacaacaat gcaccatcaa cagagatcat
     3181 tacggataaa acagtggaaa aagcgaatat attcgtgatt ggctggcgac gcgtcgcaga
     3241 atttttcggc aacttgtttt aattgaacaa taagaaaaac atctttccat cggaaagatg
     3301 tttttttgct ttttctagtt taaataacag cttttttcat ctattttcgt tatactgtat
     3361 aagaaaaagg agttgaattt atgaatctaa ccagagatct gatcttttta gttctctatc
     3421 ttattggggt attctctatc gtttattggc gaaaacagaa gaaggatcct tccttgttct
     3481 tttacggcag tacgtggaca tttacggtaa tcttaactta ttttgtcgtg ttggaaattt
     3541 tttattcgac cttttatttt ttgattccat tgttgttctt tagtatcttt gctttttctt
     3601 atttcacaga aaaacgaagg ctactgaatg gtcttttatt caatgtttta ctcatcagtt
     3661 tcggcatcta cttgtttgtc ttgctgtatg aaacgcaaaa tatttttctt ggcggactga
     3721 tcgccttgat cacgattcca ttgctacttg tccttttatt tggtatttat ggattgattg
     3781 tttttctttt ttggaacggg gtcacagttt tacgtagaga atcgcattca ttagctaatc
     3841 ttttaacgtt gatactagcc atttttctta cactgtttct tgtttttgac tttttcttgt
     3901 taaaatattt gccgcaatgg ataaatgctt tgtttttctg cgttcccctg atcttgatct
     3961 atctatttat cgtattctac aactttttga ctgtctcatt cttgtatcag ttcaaccggc
     4021 ctcgatacaa tcaagacttc atcgttgtgt taggcgctgg attgatcaat ggagaaacag
     4081 tttctcctct tctagccaag cgaatcaata aggcaattgc tttttatcgg gctcaaagcc
     4141 gtgctacatt aaatccgccc atcttattga tgtctggcgg gcaaggagca gacgaaaaag
     4201 taccagaggc cattgcgatg aaacaatatg ccatggaaca aggaatccct gaaagagaca
     4261 ttcttgtcga aaccaattcg acaaccactt tggaaaacat gctctattca aaggaaatca
     4321 tggatcagca aatgaaaggg ccataccgcg cgatctttag ttccaacaat taccacattt
     4381 ttagagccgg tctttatgcg cggcaagcca aattgaaagc aaatggtatt ggtgcaaaaa
     4441 cagctttcta ctacttgcct aatgcgtttt taagagaata cctcgccatc ttgatgatga
     4501 acaaaaaaag acatatgatc atttgcggat tgcttttcgc aggctccgca ttcttatcgc
     4561 tgattacttt acttttctaa aaaaacaagg tgtgacaaaa catatgtcac accttgtttt
     4621 tttctttcat tctcttaact attggcaaaa agagtatccc ttttttgacc gctacttgct
     4681 gagcagaata aataccgctg ttgcctgaac acataaagct gatcaagcag atcataaaga
     4741 agtatactgc cgcttgtgaa ccgaacaatt cgatccccat cacaaagcag gcaatcggtg
     4801 tatttgtcgc accagaaaat actccgataa agcccaatcc tgcaagaaaa ggaacagaaa
     4861 catggagcaa aggcgctagt gctgcaccaa gcgttgcacc aatttcaaac aatggtgtca
     4921 cttctccccc ttgatatccc gcgcctaaag acaaaactgt gaagaataac ttcccaataa
     4981 aatcatagac atgtgcctgt ccattaaatg attcttgaag taacggaaga ctcaatccga
     5041 gataacgttg tgtttgcaaa atcaatgctg ctgccacaac tacagctcca cctatcgtat
     5101 ttcgacaaac aggatgagga atccattgtg catatcgcgc ttttaaaaag acgatcgaac
     5161 ggctgaatac ccaaccaatc aaaccaaaag caatcccagc aacaaaaact ttgaagaaca
     5221 gcaacatact ccattcagga atcacaccca tttggtaatg tagatgagaa acaccatagc
     5281 tttctgtcat gaaatttgca aacagtgcag caaagaagct agggaagatc gcttctgttc
     5341 ggactttccc gattgccaac acttctaatc caaataatgt tccagctaaa ggtgtgccaa
     5401 atacagaact aaaacccgca ctgattccac tgataatcaa gatttcccgt tctgatttat
     5461 ccaatcggaa caaacgtgcc gtattatctg ctaacgctcc ccccatttgg actgctgttc
     5521 cttcacggcc aacagatccc ccaaataaat gggtagttat ggttccaaac agtgtaagtg
     5581 gaataagccg caacgggatt ttttcttctc caccatttcc ttgatcgatc actaagttgt
     5641 ttccacgact agaaagtccg ccgtgatacg catagagata agcaaaaagc gcaccactaa
     5701 ctggtagtag acaaaggagc caaggatgtg atagtcggat atctgtcaca actgtcaggc
     5761 tatttaagaa aaaagcagac aagctcccca tgaatatacc gagaatcgct gtgatcacca
     5821 gccacttcag catatacact aaaatgcgta ctggactcgg taattgtttt tccataaaaa
     5881 attcctcctc aataaaaaaa cgcctactaa agaaaggggc tgtccccaga ctttagtagg
     5941 cgtcattagc tatctttcgt tagcatttaa aggcgaacac catcacctat tcacttccat
     6001 taaaagatag catatttttc tgtaaaaaac aataaaatta tcgttctttc tttacacgtt
     6061 cagcaaattc atagaaagga gccaatttcg ttaactgttg attacattgg tcactatcat
     6121 gacaaatata attccccttt ttcgtatacg tgccatcaga acctgctttc gttgtagaaa
     6181 gaaaaagcga aacattcgat gttttctgac agattgcaca gattccctta tttatcgttg
     6241 gtgataaagt accgctaatc ccttttaatt tttcatcttc gtaatagacc atgaattttt
     6301 tctgcgtacc tggatcattc cagccgatgt acgtatgttc ttgcaagtcg atttcattcc
     6361 aagctggttg tttgagtttt ttcacttttc ggaataattt ctcgatttgt ggtttgctag
     6421 gctgcataaa cggctgaacg atttgcttca gctcctccaa tgctctttct gcttgcgctt
     6481 ttgtcagttt tacgtctaaa actgtcgtta aaaatgtatc gattctggca gttcgtgatc
     6541 taatatgtct cgaatctttt cagctgctag tgcctgaact gtttgtaccg tttttggatc
     6601 attgacagat gagtacgcat ttaataactg ttctacttct cttattataa aaaaatattg
     6661 gtatggtttt attgtttgtt ccatgatttt aaagtccttt cttctaacca aagtgcatac
     6721 tttgtagaaa aaagtgatct tctgcaaagt atgtgttacc tgaagatccc ggactctttt
     6781 aaataagata cgttttgcat cttatcatca ccccctttaa tgcttattat tctatgtaca
     6841 tgattcattc gataaataaa agtaaaccgt atcttgaaca gatagtcaac tgcaaacaga
     6901 aaaaaggact gtgacaaaag tcgtgtcaaa gtcccttgtt tcgaatgaat ggtgttcaaa
     6961 agctggcatc tgcggtaata agccgaaact tcacaaaaat ttgagaagca attttcgtaa
     7021 attccttctt atttcttgaa gctgaccact tctgtcacaa cctcaatatg gtctattatt
     7081 ggttttatct attaaatcga ggattctttc ccaaagtaac gttgccatct cttacgcata
     7141 cttgctgaca taggctgagc ggcttctttg actgcgcagt atttgtctac gaatgttacg
     7201 atatatcctt ctttgtactt aggcggtgca atcgttgcgc cccacatgtg cttcaaaatg
     7261 atatctcgct caagatccga caattcggtg atcttttctg cattctttac agcaattctt
     7321 ggatggatat acgcatgtgt gccttcatca aatttcgtcg tacgccaatc atagtagaac
     7381 agatcatgca aaagtccagc acgcgctgtt gctttagcat tgccacccca tttttttgcg
     7441 agcagataac tatagtaaga aacactgatg gaatgctcca aacgagtgga atgaacatgc
     7501 tgtgtgtaat tcgctaattt tttcactgct tctgtttcta aaagatcttc tacataagac
     7561 atatattctt cgtcttcacg ccatttttct gtcataatta tcgatctgcc acctttttga
     7621 atttcatttt cttctgaaat tgatctaagt ataccaccag tgttcggatt attctagtcg
     7681 ccttggataa aatagccaaa gcttaatagt tccttaatca taaagaaaaa tgataaagaa
     7741 caatccctgc cgcaacccca acattcaacg attccgcatt tcctttcatc gggatatata
     7801 cgttctgatc agtcaaagac aagatttcct gacttacccc ctgaccttcg ttccccatga
     7861 ttattgcgaa gttatctgat ttttctactt tgtctaatgc gtgtgcttct tcatttaatt
     7921 ctgtgccata cactgtaaac cctttgtctt tcattaaaga aatcacttct gtcaaatctt
     7981 tttgcaacac aggcaaatga taattgcttc cctgcatgct gcgcagcacc tttgtactat
     8041 aaatatctgc cgttcctttg cctaataaaa caccagccat atcaaatgca tctgccgtac
     8101 ggatcatcgt ccctacattt ccaggatctt gtacattatc taacaacagc catcctcctg
     8161 aaaaatctgg cgtgccttca gccgttaacg ccatcactgc taagattcct tgtggtgtag
     8221 gtagatccga tacagcatcc atgacctcat ccgaaactag aaaagtagaa atctctttgt
     8281 ttgcggccag ccagtctccc cattctttca tgcctcgctg tgtcacaaaa agttctttta
     8341 tttctgcatc agacgacgca gcttcttcaa tcagatggaa cccttccaaa agatattctt
     8401 ccttttcttc ccgatatttc tttttatgta gtttttttaa ttctttgatt cttggatttt
     8461 ttgctgattg gatctctttc acattcctca cctccccatg attatatcat ggaataggtg
     8521 cttgagcttg tttcatccta aaaaaatcgg tatcattaat ttataaaata ggaaagaaag
     8581 gtgacgaaca tgcgcaaagt taaaatgaac gtccaaggac gcgtccaagg cgtaggattt
     8641 cgctacatga ccaagatggt cgctgatcaa ctaggcgtga ctggaacggt aaaaaacgaa
     8701 gatgacggct cagtcacgat cgaagcaatc ggcaatgacg acatcatcca gaaatttatt
     8761 gaagaagtca agaaatctcc gagcccaagt ggacgagtgc agtatgtgga tgtccaagaa
     8821 gacccgatga ttgaggaacg aaagaaattt gatgtggtgg gataaggttg tgaaaaagct
     8881 ggtctgcatc aagcattaag gacaggttgt gaaaaatagc tctccatatt tttcaacagg
     8941 ctggacttaa tgccgtagat gcaagctttt gaacaccgtc gataaggtta ttcttgaggc
     9001 gctttgcctc aaaaattaag gacagcagtg aaaaagctga tctatcactt gcagtgagtt
     9061 catttgactc cgctttttcg ggcagaaaaa aagtttttag tttattaaag taagaaagaa
     9121 acacttggaa tcattctact ttttcctagt atttctttct tgattttttg tctttttttc
     9181 aaaatttttc gctacgtaaa agaacgaata tttatatgaa atttctatga agttgattga
     9241 attccatgcg cttttttagt atagttaagt ttgtgtaaaa attatagaag aggaagtatt
     9301 ctatgaataa atggaaaaac tggttattgg gatccggact tgtcagtatc ctgctctttt
     9361 tatctggctg tgtgcggatg gattcaaacg gaaaccctga cacttcggga atcgtttatc
     9421 gagtactcgt ccatcctatg ggccaagcga ttacatatct agttgaaaat ttcaattggt
     9481 cttatggctg ggcagttatt gcaatgactg tgatcgtccg tatcatcatc ttgccactag
     9541 gtattagtca atcgaaaaaa acaatgatcc aatctgaaaa aatgcaagcg ttaaaaccac
     9601 aagttgaagc agcccaacaa aaattgaaag ctgcaacaac acgtgaagaa caaatggcag
     9661 cacaagcaga aatgcagcaa gtataccgcg aaaacggatt gagtatgacc ggcggaatcg
     9721 gctgtctgcc tctattgatc caaatgccga tcttctctgc cttgtacttt acggcacgtt
     9781 atacagaagg tatccgggaa tcatctttct acggcatcga tttaggctca ccaagtatgg
     9841 tacttgttgc cattgcaggg gtcgcttatc tgcttcaagg atacatctca acgatcggta
     9901 ttcctgaaga acagaaaaag acgatgcgta cgatgctgat cgtctctcct gctatgatcg
     9961 tcttcatgtc gatcagtgcg ccagccggtg ttacacttta ctgggtagtc ggtggtgtgt
    10021 tcagctgtct gcaaacattc atcacaaacg ttatgatgaa accacgtttg aaagcacaag
    10081 tggcagaaga gttgaaacaa aacccaccaa aacaagtcgt cactccaaga attgatgtga
    10141 cagaatcagc taaaccagct gacagcaaac aagcaaccaa acaaatcaag caacccaaaa
    10201 acagtacaaa caataaaggc cgcaacgcag gaaagcagca gaagcggaag tagatagtaa
    10261 ataagagtgt aataaaaatt cattaacagt tttagcaatt aaaaatatcg accaagattt
    10321 ttgaaaaaga aatctggtcg atatttttat ttaagtgaat gtttaatttg aatcatcgat
    10381 tgatcgctat ctaattgcag cagcatcttt ttatgaagaa acaacttttt cttatctatc
    10441 aacgtagaca ggtgttgctg tttcttctaa tagtgtactt aattccttaa tattttgttt
    10501 tccttcttct aacatccaac tactcgcttt ttcttcgcct tcggtaacaa aaggcgccac
    10561 tcccttcgcc catgttgctc gcccacataa gacaccattc tccataaagg acaacgcgga
    10621 gataccaccc atctaaataa catccataaa cctttctagt agaagaatag tgatagtatc
    10681 catccctttt tctactggga atacaattac acgattcaaa gcttgataca caacatttcc
    10741 cttcttataa accgctattg taaccgaatt gttttgaatc acctttttgg gatagaaact
    10801 ggctcctttc cgcaacttct taaatgttgg tttcttttat actttctttg tagcaactac
    10861 aaatttcttc aaatctctaa atgtttgcat aacaaccgcc tttctgactt ttactcagga
    10921 tggtatttaa aaatcagcaa aataaggctt ctctccatct tttttatttc ctagctgctt
    10981 taaagacact cttgctgttt tttaatctct atcaaggggg ctctgaatct attttgatga
    11041 acttatctta ttaatttctc aaatgagctg tcagacacaa ctgtattttt tcaatctcat
    11101 accggacaac tatgccagct taaaaaaatt tcctctggca aaacttcttt attgaaaaat
    11161 gacaatgaaa aaagaccatt ctttttgttg aatgctcatt gtgtaaacat atttcctgcg
    11221 actgctcttc gaaccattct cagtgcaatc cctaatttat ctattaaatc ttcttttagt
    11281 tcctcatctt tcatattcaa aatttccttt gtatgttaca caagtttgtt ctctaaataa
    11341 cgcgaattgt aaaattaagt tagaaaaata aaaaggcatt tatggtacac tcaaattgta
    11401 tttccgacga aagaaaacaa aggagtgtaa ccataaatga cctacaaaca tcttaccata
    11461 gacgaactga caatgataga atcatattat cttcaacata ataagccggt tgaaatcgct
    11521 aaccgaatgg gacgtgctat acaaactatt tataatgtag tcaataagtt caagcaagg
//
LOCUS       DAPBAF010000070        10687 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.072, whole genome shotgun sequence.
ACCESSION   DAPBAF010000070 DAPBAF010000000
VERSION     DAPBAF010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10687)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10687)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10687
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.072"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(231..1079)
                     /locus_tag="RD451_002547"
     CDS             complement(231..1079)
                     /locus_tag="RD451_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDT7567757.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            1078..2145
                     /gene="gnd"
                     /locus_tag="RD451_002548"
     CDS             1078..2145
                     /gene="gnd"
                     /locus_tag="RD451_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating 6-phosphogluconate
                     dehydrogenase"
                     /protein_id="HDT7567758.1"
                     /translation="MRIPHFHNKIIIFSVLINVKDTRRVGKNQTKNIFVKSIYKKIFL
                     YNEGIRNGGAIMEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDIPAY
                     QEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSIRRA
                     EEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLYAGA
                     SGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWLMEI
                     MEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEEDSFS
                     AKVVSALRNGFGGHEIVEKGE"
     gene            2147..3148
                     /locus_tag="RD451_002549"
     CDS             2147..3148
                     /locus_tag="RD451_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HDT7567759.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALVERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            3145..3429
                     /locus_tag="RD451_002550"
     CDS             3145..3429
                     /locus_tag="RD451_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HDT7567760.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            3462..4259
                     /locus_tag="RD451_002551"
     CDS             3462..4259
                     /locus_tag="RD451_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HDT7567761.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNVAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            4273..5106
                     /locus_tag="RD451_002552"
     CDS             4273..5106
                     /locus_tag="RD451_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDT7567762.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            5124..5981
                     /locus_tag="RD451_002553"
     CDS             5124..5981
                     /locus_tag="RD451_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDT7567763.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGSNATGLKQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            6003..6512
                     /locus_tag="RD451_002554"
     CDS             6003..6512
                     /locus_tag="RD451_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDT7567764.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            6549..6950
                     /locus_tag="RD451_002555"
     CDS             6549..6950
                     /locus_tag="RD451_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567765.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            7062..7415
                     /locus_tag="RD451_002556"
     CDS             7062..7415
                     /locus_tag="RD451_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567766.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            7449..7892
                     /locus_tag="RD451_002557"
     CDS             7449..7892
                     /locus_tag="RD451_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HDT7567767.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            7909..8994
                     /gene="uxuA"
                     /locus_tag="RD451_002558"
     CDS             7909..8994
                     /gene="uxuA"
                     /locus_tag="RD451_002558"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HDT7567768.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            8987..9700
                     /locus_tag="RD451_002559"
     CDS             8987..9700
                     /locus_tag="RD451_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HDT7567769.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
     gene            complement(9907..10056)
                     /locus_tag="RD451_002560"
     CDS             complement(9907..10056)
                     /locus_tag="RD451_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567770.1"
                     /translation="MTFYNKDIQYRVTLDTDLNLFVVFDKENTNHVATGVTIEQAVQE
                     LKKSA"
     gene            10452..10652
                     /locus_tag="RD451_002561"
     CDS             10452..10652
                     /locus_tag="RD451_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDT7567771.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
BASE COUNT         3573 a         1690 c         2314 g         3110 t
ORIGIN      
        1 aaaaaaagaa aagataaatt ttttactact gtatactaac tttgttatcg catctaacaa
       61 gtaactcgaa taataccaat acaaccttct ccaaagatgc gatgacatac gttctaaccc
      121 accgactatt gatgttctgt accacccttg cagaaccaaa aaagccacta ccaaatattt
      181 ggtagtggct ttttttgttt tatggatttt tcgctttttc tgttatggtg ctattctttg
      241 atttcagaaa tagtatgtcg aactttagcg atagaacgac gtgattcttt ttcgttgtaa
      301 aacatcaaaa tcacatatag agagtccaaa atgcttagtt gagaaatacg ggaagctaaa
      361 gcttcagatc ggaattctgt ttcttcagaa atagaaataa aaacgacatc gccaagttta
      421 gcaagggaag aattagcttg gctagtaata acgattgttt ttgctccagt ttttcttacg
      481 gtttcagcaa tatggattgt ttcttttgat tgccctgtgt gagaaatcaa aacagcacag
      541 tctttttccg tcaataaaga agcttccatc aattgaatat ggtaatccgt gctgtgagaa
      601 gttgcgatag gggaacgcaa aaatttatga taagcgtcag ttgctacaat ctctgaaccg
      661 ccaacaccga aaaaatagac acgtttagat tcattgataa tagtagccgc tttttttaga
      721 tccttttgtt gtaacaactt ttttgtgtca tttaaagttg aaatactaga ctcgaacacc
      781 ttttgcgcca tagtgagctc agtatctgtt ttctgaatat tttcgtggat agaaatagca
      841 gatagatcat tttcttggat caacatggcc attttaaaat ctttaaatcc attataacca
      901 agtttttttg taaattgaaa aaaagtagag tcagcaatgc ccagttcact tgctaaattg
      961 ctaataggac tatgacttac tttgcttgga ttttctaaaa tataatcggc gatagcctgt
     1021 tcttttgggc tgaagtcgtt gtacattgtt ttgatttgta gtcttatgga gacgctcatg
     1081 agaattcctc attttcataa taagattatc attttttccg ttctcattaa tgttaaagat
     1141 acaaggagag taggaaaaaa tcaaacaaaa aatatttttg taaaatctat ttacaaaaaa
     1201 atttttttgt ataatgaggg tataagaaat ggaggcgcta tcatggaaat tggtgtaatt
     1261 ggtttgggaa aaatgggatt gaatttagct ttaaacttaa aagagcacca tcacaaagta
     1321 caaggactcg acatttcaag tacagctgtt agtcaggcaa gagaaaatga cattcctgct
     1381 tatcaagaga tctctgaatt tctagctact tttgagcaga aaaaaatcat ctggttaatg
     1441 cttcctgctg gagagataac cgaaaacatg ttaagaaaac tttttccaaa actcggacca
     1501 ggagacatta ttattgaagg cggaaactct tattataaag attcaatccg tcgagcagaa
     1561 gagtttcaga aaaatgaaat cggttacttg gattgtggga cttctggagg aatcgaagga
     1621 gcacgacatc aagcctgctt aatgattgga ggagataaag aaacttttct atccgtggaa
     1681 caattattca aagatgtagc aattgaaaga ggatatctgt atgctggtgc atccggaagc
     1741 ggacacttct tgaaaatgat ccataatgga atcgaatatg gaatgatgca agcaatcggt
     1801 gaaggattcc aacttgtaca aaaaagtgag tatgcttttg acttggaaca agtcgcacgt
     1861 gtttggaatc atggttcggt gattcgcggc tggctgatgg aaatcatgga agatcagtta
     1921 aacgaacatc ccaatttaag taattatcgg ggaatcgttt ctgcatcagg tgaagcaaaa
     1981 tggacggttg aaacagcgct agaaatggct gttccagttc cagtaattgc aactagtttg
     2041 ttcatgagga atctttcaca ggaagaagat agtttttcag caaaagtagt ttcagcacta
     2101 agaaatgggt ttggcggaca tgaaatagtt gaaaagggtg agtaaaatgc cagattatca
     2161 tatagcaatc gttaattcca gcagtttcgg aagagtcttt ccacaccact tggaaagatt
     2221 aaagtcagtt ggagacgttc atttctttac tgttgatcaa gagattccag gaaaagaact
     2281 agcggagtta cttaaaggat tcaatatcat tattgcaagt gttacgccat tttttcgacg
     2341 agattttttt gaaaacaaag atgaactgct attgatttcc cgacatggta ttggttacaa
     2401 caatattgat ttaaaagcag caaaagaaca ccagacaatc gtatctatca tacctgcttt
     2461 agttgaacga aatgctgtag cagaaaataa tataactaat ttgttgtcca tgcttcgacg
     2521 cacgacacaa gcacaagcaa gagtcaagga cgatcgatgg gaagatcggg cggagttcgt
     2581 cggtaggacg ctgtttaaca aaacagttgg tgtgattggt gcaggaaata ccggaagcgg
     2641 agtaatcgaa attttgcgta acggttttcg ctgtgatgtt ctagcttatg atccttacaa
     2701 atcagattta tacatcgaaa gctttggtgc aaaaaaagta gaacttcaag aattactgga
     2761 acaatcagat atcatttgtt tatgtgcgaa tttgacagaa gagaactatc acatgatttc
     2821 tgataaagaa gtcgatcaga tgaaagaaaa tgtttatcta tctaatagtg caagaggcgc
     2881 tctagttgat gaagaagcga tgattaatgg tctgaaaagc ggaaagatcg caggatatgc
     2941 cacagatgtt ttagaagaag aaccgggacg tcaagatcat ccgtatttag cgtttgaaca
     3001 agtagtgatt acgccacata tatcggccta cacaagggaa tgtttagaag caatgggtga
     3061 aaaatgtgtc agagatgtcg aacagatcag tcagcacctt cttcctgaac gttctgtcca
     3121 gacaaagagc aactatataa aaggatgatg aagaaaatgg tgaacggttt aaaagtgaaa
     3181 acaggccctc aattttattt atatgaagaa ggtggtattt caaaagtttc tgatctcttg
     3241 aaatcatacg gcgcgaaaag agtactggtc acccacggaa cggtatcatg ggaaaaggcg
     3301 ctacctaaat tagtattttt gaatgacgaa acgattcaat ttttttatca tcgttattct
     3361 ggagaatgta gttatgctga agccagacga atagctacaa tcatcaaaaa aatgaaatcg
     3421 atttcgtagt tggcgttggc ggaggaaaac tgaccgatct agtgggttat agtgccaatc
     3481 ttgcaagaat cgatttcgga gtcatcccta ctttagctag taattgtgct ccatggacac
     3541 ctcttgctgt catgtataag gagaatggac aagcagaagg gaaaacagaa cacttttaca
     3601 gacaagctgc tttttttata acagatcccc aattagtgat tgattcccct gttccatatt
     3661 tcattgccgg gttagcagat acactagcaa aatggtatga atctgagctc atcttagaac
     3721 aagatttttt gcaagatgaa tcatttttga agctagcaca agatactgcg aagatctgca
     3781 aagaagagat tttgaatcat tctgctaaag caatccaaga tatggcacaa agaaaactga
     3841 catcggagtt caaacagctt tcagagatta tctttgctgt tgctggttta gttggaggat
     3901 taggagataa atacgcaaga aatgtggcag cacatgctat gcatgacgct atcagtaaat
     3961 atattccgga aagccatcgt tttctacatg gagaaaaagt agcgtatggg attttctatc
     4021 aactggcact agaaggtcgc tgggaaaaaa tagacgagtt atatcctttg tatcgggaat
     4081 tagaactgcc ggtttctcta gaacaaatgg gattatttcc gaaagataaa cagataatag
     4141 ataaaatggc tgaatttatt gattcgaaag agaaagtgca tttgattcct atagaggtaa
     4201 cacagaaatc actgatacag tcaatgatgg aactggaagg ttatatcaga aagatctgaa
     4261 ggaggaggac acatggaaac attaagtgta gtacaaagtt tgttgattgc tttatgggta
     4321 gccgcggtta tgtcccgctg gttaggtgga ggagccacgt tgaccttacg tttttctcct
     4381 ttgatgactg gattagtcgt cgggttgatc atgggggaag ttgcacaagc gatgattgtt
     4441 acagccgctt tgcaaatgat ttatatgggg gttttttctc caggaggatc aatgccagct
     4501 gaaccatcta ttgcagcagc tatcgcagta ccagtcgcat tattagggga tctgtcgcca
     4561 gaagcagcga ttgccgttgc ggtgccagtc ggattgctcg gaagttactt gtatcagttt
     4621 cgttttttca tcaatacttt tttaggtaaa tatacagaca aagctgtaga agatttgaat
     4681 acaaaagcta tggcccgatc aattattctt tatccaacgg ttgcctcatt tttattattc
     4741 gttccgcttg ttttcattgc tttatattta ggggcgccat tgatcgctga tgtaatcaaa
     4801 gctttagagg gaacagtcgt tatccacatt cttgaagtag taggtggagg gttagcggca
     4861 atcggtatcg cgacaactgt atacgttatc ggtcgaaaag attatctggt ctttttcttc
     4921 cttgcttatt ttatgagtgt tgttttgaaa tctttagata ttacgatggt tacttatgcc
     4981 atttttggga ttattatcgc tttgatcttt gtccagtcgc aaaaagggaa acaagtacag
     5041 cctgccacaa gcaataacaa ttcagcatct tttgatgacg aagatgacta tgatgacgga
     5101 ttttaattta ggaggaatgg gaaatggctg aaataatgga taatcaaaca ggtgctcctg
     5161 aagaaatcac gaaaaaagat gtaacaaaag cctatctgag atggcatttt gcaaacgaaa
     5221 ttcctcactc ttttgaacgt tacttggcgc catcactact atacggaatg atgccaatct
     5281 tgaaaaaact ttataaagat gaagactctt taaaagcagc atataaacgg cagttactgt
     5341 tcttcaacac tcaattaagc tggggtggcg gtgtgattac tggcctaatg tcttctatgg
     5401 aacagcaaag agcagaagaa gagtatgaag aaaaagagat cttgatgcag gatgacttga
     5461 tgtataacac gaaagcggga ttgatggggg cactagcagg aatcggagat gcaatcgatt
     5521 caggaaccgt ccaatatatt tttatcgcaa tcgcggtacc ttgggcacaa cagggaagtc
     5581 ctttaggcgc actttttcct tttatctgct ttgggttgta tcaggtttta ctaggggtat
     5641 ttttcgcaag acaagctttc actatgggca gtaatgctac aggcctaaag caaaacactg
     5701 gtgttcagac agcgattgaa atgctatcag ttttagggtt gtttatgatg ggggtgcttg
     5761 cgggaaacta tgtaaaagta gaatcttcat tgaaatttgc gatatccgga cgtgagtttg
     5821 ttatccagga aattcttgat caaatcgtgc cagggatatt acctttagct gtcgtaatgg
     5881 gtgtgtactt gttctatacg aaaaaaggat tgaaagtcac acaagcatta ttatggctga
     5941 ctggaatatt aattgtgcta gcaggaatcg gtattttata aaaagaaggg aacgtgaata
     6001 agatgggtgt agtcaattta gcgcgtgtgg atgagcgttt gatccatggg caagtaatgg
     6061 taacgttatc tcaaaaaagt ggagtgaatt ccatttttgt tgtagacgaa gttgtagcaa
     6121 aagataaatt tatgagagat ctttacaaaa atgcaggaag ccgtacagga caaaaaacaa
     6181 ttgtcattac accagagaaa gctaaattct attgggatga atatcaattt aaagaataca
     6241 attgtatttt gatcgcaaaa acagtccaaa cgatttacga cttagtaaaa cacggaatcc
     6301 ccatggaaga attgaatatt ggagggattg ctcaaaaaaa tcctgataca gatcttttag
     6361 tgacgaaatc tgtttattta aataaatcag atgctgaaaa attgaaagaa atgaatgaac
     6421 aatatggcgt aaagaatatt tattttcaag ccactccatc tgcacctaaa acaggattaa
     6481 aagatgtatt gaacaagttt gatttgtcat aaacaaatgc ttagaaaaaa gataaagagg
     6541 gcgaaaaaat gaagaagaac gagctgtttc gtgattggga atttcgttat cgctatattt
     6601 accgtaagcg ccgtacaaaa aagagtaaac agcgttttct ttcagcatta gtatcagata
     6661 tttacagtat gagaacagat gtgacagtca ttgcttacga tacgctagcc taccgatcaa
     6721 aaaatattta tgttggagat atcgaaaaag cagagaaagt tatctgtact tattacgata
     6781 cacccgttca tgcattagga agttatttca tgtttgattg gaaagaccaa aggaaaaaaa
     6841 caatctactc tatattattg tccttcattt tgttgttcag tttaggttgg tggggaatga
     6901 tgatatataa caaaaatcct catcacgtat tcgatctgct atccgtataa acaggtatca
     6961 ctgtactagc atttgggagc tactttttct tattgggaaa agcagctcgc ggatggccta
     7021 gcagacaaac ttttattcga aatacttcat ccatattaac gatgctagaa atgatccgta
     7081 cgattgatga tccgagtgta gcgtatgcgt ttgttgatga aggctgttat ggagaaaagg
     7141 gcttagacag cgtgagatcg ggtatgaaaa aagaggctat tcttttttat ctagactctg
     7201 ttggggcaga tacaccgcta cagttttcgg gaaattattt ttcaaataaa gaacagtggc
     7261 tgaaacaagt tgataagttg aaagaaaaaa acgtcaatta tatttttagt gcaagaaaaa
     7321 agcaagcgca gttcttctat ttgaccaaaa cagatttacg agggaaaaca tttaattggc
     7381 aaaatgccaa tcagattatt gctctttttc gataagtaaa aagtgcaaaa caaggagtga
     7441 gaagactaat gttggaaatc atgatcgtta cacatggtaa gttgagcgaa ggactgaaag
     7501 atgcggcgga agtaattgtc gggacatcga gccatattga aacaatgtgc ttagagtctg
     7561 gggaggacat ccaaacattc ggagagaagg tcaaagaaaa attaactatg atcaacacag
     7621 cagaacccat gctagtattt gttgatctaa ttagcgcaag tccgtacaat caagcgctct
     7681 tggcagtcaa tgaactgact gaagaaaaga aagcagccac ttatgtcata gggggcgtga
     7741 atctgccaat gttgttagaa gcaatcaatc atcagatgct tcacacaccg atagaagaag
     7801 cggtggaaca aattgtcaaa caaggaaaag ataatttaac tgtttggcat gcttcagcgg
     7861 aagaaaaaaa attagatgag gacgattttt agaaggaagg ctgaaaagat gaagtgggga
     7921 tttagatggt atggtgaaaa aggggattcg atcccattaa aatatgttcg ccaaataccg
     7981 ggaataaatg ggataattgg aactttgctg actaaaatgc ctggagatgt ttgggagatt
     8041 tcagaaattg aggagttgaa agcatctgtt gagagccaag gactggaact gcttggaatt
     8101 gaaagtgtag cgatccacga tgcaatcaag gcagggacag atgaacgaga ttactatatt
     8161 gataactata tacgaacaat caaaaacttg tctcgatgtg gggttcgatt gatttgttat
     8221 agcttcaaac caatttttgg atgggcgaaa actgatttgt ttaatgaaaa caacgatgga
     8281 agctattctc ttttatacga tcagaaaatc gtcgatcaga tggagccagg agaaatgtat
     8341 caattgatac acagccagtc aaagggattc aaattgccgg gttgggaaga agaacggttg
     8401 aaaaaattcg ctcagctgga aaaactgtat gaaggaatga ccgaagaaga attatttgaa
     8461 aatctgactt attttttaga aaaagtgatt ccagtgtgcg aaaaagcaga tgtaaaaatg
     8521 gctatccatc cagatgatcc gccatgggaa ctttttggtt ttcctagagt gacgaaaaat
     8581 cttggcgact tgaagaaaat tctaaatgca gtagattctc catataatgg actaacgctg
     8641 tgcacaggat ctttaggggc aaatccggaa aacgatttag ttgaaatcat ccatgaggta
     8701 ggttcgcgca tccattttgt ccacttcaga aacgtggagt ttttaggaga aagaaagttc
     8761 aaagaaacgg cacatccctc tacagaaggc tcccttgata tgtatcatat tatgaaagcg
     8821 ttggtgcaag aagggttcga cggtcctata cgccctgatc atggtagaac cgtgtggggt
     8881 gaagtggcta tgcctggata tggcctgtat gatcgtgcaa tgggactcac ttacatgcaa
     8941 ggtctatatg aggcgataag taaggaaaaa ccactgggag agcattatga ataaaatcaa
     9001 gctcttcatc tttgatatgg atggcctttt attagaaact ggacgtttag cttatcgtgc
     9061 ttatgtaaaa tcagcacaaa agtatgatta tgaaatgcgt aaggaagtct attatttact
     9121 aactggccaa acagaaatgg cgataagaga acaaatgggc attttgtacg gagaagatgt
     9181 tccatatatc aaatggcgag aagcaatcaa tcaatataaa gaaaaaatcg tgaaagaaga
     9241 taagagagta tatacgaaaa aaggagcaga agaaatttta tcttttgcaa aagaaagagg
     9301 aatccataca atcgtggctt cgtctaatac acgggtaaaa gtagaaatgt atttaaaaat
     9361 ggaaaatcta tatgccttgt ttgatcaaat catttcaggg gatgatgtaa aaaaaggaaa
     9421 gccggaacca gagatctttt tgaaagcttg ttcaaaaatg aatattcctc caagtgaagc
     9481 acttgtattt gaagactcga ttgcagggat cgaagcagca aggcgagcgg gcattttgtc
     9541 ttttctcatc aaagatcatt tgatagggtt gcccgatcat aatgggaagc ataagttgaa
     9601 agtagatgta agtttatatg aatccaataa agcagactat gaattttatg acctgcatca
     9661 agcaaaacga tttttagaaa gtaaagggtt gtatctctaa taaagaggac tattttctag
     9721 tcctctttat ttattgtcct gcacgactga gggaacagat gaaaaagaag taatttttta
     9781 ttttgaagta tctaccttat ttgtagtgaa caatttagaa caaacacaaa acgcatctac
     9841 tgttatctac cagtagatgc gtttaaagag aagaacgaga atcgtccata tgagggtttc
     9901 cactccttat gcagattttt ttaattcttg cactgcttgt tcgatcgtaa cacctgtcgc
     9961 tacatgattg gtattttctt tgtcaaaaac gacaaataga ttcaaatctg tatccaaggt
    10021 tactcgatat tgtatatctt tgttatagaa tgtcatagcc attctccttt ctttaaatac
    10081 ttgctgaaag gcaacgaacg cgttgataac gaaattccat ttataagtat accaccaatt
    10141 gaaaggtttt catagttaag aaattttaaa gtcaaaagtt gcagataaaa gcaaataaac
    10201 aagaaaacaa aaagtgaatc aatcgcggtt attcaacttt ttcttcgatt cgaagacaat
    10261 agaagacaat gaattttata tttcattgca ttatccttgt gttattagaa aaagcatgat
    10321 atattaaatg agtaatctat tttgaaacgt aatttgagcg atatatctac atagataaaa
    10381 ctccttttgc ctatcaaata tttattgcaa cgaaaaaacg tacattgata cgtatcagga
    10441 ggaatttatt tatgaataac ggtacagtaa aatggttcaa cgcagacaaa ggttttggct
    10501 ttatcactgg tgaagatgga aatgatgtat ttgcacattt ttcagctatc caaggtgacg
    10561 gcttcaaaac tttagaagaa ggccaagcag tgtcttacga tgttgaagat ggtcaacgtg
    10621 gccctcaagc aacaaacatt gttaaagctt aataaaaatt gacttttaac cgtcttttcg
    10681 aaagaaa
//
LOCUS       DAPBAF010000071        10661 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.073, whole genome shotgun sequence.
ACCESSION   DAPBAF010000071 DAPBAF010000000
VERSION     DAPBAF010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10661)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10661)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10661
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.073"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            333..2279
                     /locus_tag="RD451_002562"
     CDS             333..2279
                     /locus_tag="RD451_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDT7567772.1"
                     /translation="MIERHVNLLKLLSRQEDFKPASFFSDKLAVSTKTIYQDIELLED
                     YVVNYQVTIERLPSLGIKLIGDRKNVEHLISSVENYLEKDIYSPEKRRVEIIKEVLFG
                     DKPVSLTHLSQSFMVSKTSLYNDLRIINKIIGSGEVKLQSSAEGISFTGNEQAIQRAI
                     KQLVFYYANDMESKTFFQVLNMLFDSKVISVIHDLLFNDYSELTEKVSDYYVRSLIST
                     LVIQCNRLLKGHHLTVEEEFLFNSIRYMETYIVANGLIEELKAKLNLPFYDADKEYLC
                     RQLFAHRVTNNLKTSNEEYAMSVHKLIERMSEIEKIDLTQNDRLYQSLLYHVPAMVLR
                     LKKGIKIQNPLLENIKSQYSELFSIVWYAMSILEEEFDVTLTDDEVSLILIHFQIAIE
                     DQSKANNIIIICQYGISSAQLIYNKVRRFLPAKDNVEISTLDKFHLAEIGEVDLIISS
                     LSFDAGGIPLVRVSPLVSKTDYMNIMEAYTKYLIEEPSRFIQNELIPKAVKVPTISKF
                     VQSSLVKTGVQVESKEECLDLMISELEANSLVTEEFRASIFSREKMGNTNLESGVALP
                     HANPSMVIESNIFIVALKNAINWGDRKVKLVIMVSLAEEDVSEIRGVYEELYQFIGQK
                     EMVDRLLQVHDSEKLLRIFQQKGE"
     gene            2282..2737
                     /locus_tag="RD451_002563"
     CDS             2282..2737
                     /locus_tag="RD451_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDT7567773.1"
                     /translation="MYLDKELCLFQLEVKDQKELFQVMSEQLKNAGCVKDSFLEGITN
                     REQEFPTGLEVNQIGFAIPHTDSAHVNSSQICFASLKEPLVFSDMTDKSHEIPVRLVF
                     MLAMSQPHEQIDTLQNLVSLFQNEEKVNELLACTTKEAFIELVHSAGVY"
     gene            2751..4079
                     /locus_tag="RD451_002564"
     CDS             2751..4079
                     /locus_tag="RD451_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HDT7567774.1"
                     /translation="MDIVLNAFEWFIGLGSNVFLPLIIFVIGILFGLKPGKAFVSGVT
                     VGIGSIGLGLVLSLLSDGLGTAIQQMGEQYGGGLNILDIGVGVGGPLAYSTSLGILMI
                     PISLILNFIFVVLGWTKTLNVDIWNFWFAIFLGMITQSVTGNFWFGLIGAIVAVILQW
                     FLADRTQKTVSEFFGYPGISITHMMGLSGVLFAKPVNWVFDRIPGFNKIDADAETLTK
                     RFGVLGDTVVIGLIIGIVVGIMAGYDVAGIGNLGIMTAAVMKIMPKMVAMFMEGLMPI
                     AEAAKEFTNKKLNGRQVNIGMDAALTVGHPTIMSTSLLLVPISLLLALILPGNKVLPF
                     GDLAFFAFAICLMIPYFKGNIVRSLVGCSLYVVTTLYMATWLAPIITDVFTLASFDVG
                     TAGLVTMLLCGLWPVGLFVLLASYFGVIGIGGLGVVLVGASIYMNKVKKA"
     gene            4113..4397
                     /locus_tag="RD451_002565"
     CDS             4113..4397
                     /locus_tag="RD451_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDT7567775.1"
                     /translation="MKKLLVICGAGHATSTIAVAKLSKWLEEEGLTDQVKIYQSKIAD
                     ELNKIDEYDAVVSTTIVPDVIKAKVTNGLGLLTGIGTDAIYADVKERLGV"
     gene            4399..4914
                     /locus_tag="RD451_002566"
     CDS             4399..4914
                     /locus_tag="RD451_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjbQ family protein"
                     /protein_id="HDT7567776.1"
                     /translation="MRFHHDTLTIETVSGRPSYHDIRKELLDTVDTAGIENGMLVISS
                     PHTTCSLFFEETMHDTNFFGDDYLHVDINNVMETIIPKMTSENQYNSPGPKHIDFGTR
                     LSDPNYPAEKWVMLNTDAHLRSSIYGTNSMTLIVQEGKLLLGEMGRVYFVDWDQLRER
                     TRTINLMIMGE"
     gene            4930..5592
                     /gene="rpe"
                     /locus_tag="RD451_002567"
     CDS             4930..5592
                     /gene="rpe"
                     /locus_tag="RD451_002567"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HDT7567777.1"
                     /translation="MTIAPSLLNAPIAEVKELFEILKEKNVDYLHIDVMDGCFVPDMA
                     FGPSVIKDIRPLTDVVFDVHLMIDTPEKIVTRFVEAGADIVTFHIEATKHAMKVIQLV
                     KEAGAKVGITFNPATPVSFIEPVLSLVDQVLVMTINPGTENKHFIQETVVKIEQLDVI
                     RKQNDYTYDIEVDGKIDNQTIKVCSKAGADIFVSGGFIFNGKNTPQEQIDKLNQSLEE
                     VK"
     gene            5599..6171
                     /locus_tag="RD451_002568"
     CDS             5599..6171
                     /locus_tag="RD451_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDT7567778.1"
                     /translation="MTNKDQNKNYLEAIILELQNNSKRINSVELEQFSEKIVQAKHIF
                     LAGAGRSGIAMQAFTNRLMHLGFSVSLVGEISSPHSQPGDLLIICSGSGETGSLKNLA
                     AKANQSGVSIALVTMKKDSSIGQLADSVLVLPGITKDENQREEDTFSQPMGSSFEQLA
                     FLTFDSLVLSLMDKTGESSETMFARHADFE"
     gene            complement(6358..7878)
                     /locus_tag="RD451_002569"
     CDS             complement(6358..7878)
                     /locus_tag="RD451_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HDT7567779.1"
                     /translation="MTKMESELLVQIKQLTQLLEIQQQENTLLREQIAEMNRRLFGRK
                     KETPPVDGQIDLLDDSTFNEPEHTGQESQEPITVSSFKRRKRKGLKALSLEGLPEVPI
                     HYELKGADCLCEDCGHTLHDIGATRLREEPLYVPAHIEKQVIYQHAYHCRECEALGET
                     KIKKAPVPKPLINNSLGSSSIVTQSIWEKFVKKVPAYRQEKEWHALGFPLDRKKITNW
                     HIKVSEMVLEPIYNCLHQELSNQEVLHADETSYRVLNTHKEKTFYWLYASGKSEEKQV
                     VLYEHANSRSVDEPKSFLESFSGFLHTDGYAAYGKLPVNNVYCWAHVRRKFFEALGKQ
                     PSPKSHAKIGLDFCDKMFRIERTFNKLSAEERFVARKETLQPVMTEFFHWCESFAYLP
                     KSQLGKAVQYAVNHKDGLQIVLLDGRLELSNNRAERAIKELVIGRKNWLFSKSLKGAR
                     SNGIILSIIQTAVANGLNIRKYLNHLFTEIPNLSSMTPEALRAYLPWNQQIQEICK"
     gene            complement(8121..8306)
                     /locus_tag="RD451_002570"
     CDS             complement(8121..8306)
                     /locus_tag="RD451_002570"
                     /inference="COORDINATES: protein motif:HMM:NF017528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence hypothetical
                     protein"
                     /protein_id="HDT7567780.1"
                     /translation="MPMLIDATALKHIFIVCGKTDLRKGIDGLAAFVIEEYDLDVYDQ
                     ALFLFCGTKKDRFKALY"
     gene            complement(8290..8472)
                     /locus_tag="RD451_002571"
     CDS             complement(8290..8472)
                     /locus_tag="RD451_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567781.1"
                     /translation="MNKKDIVPVQFSSAAQKSQIDTKPKLACRIKSEDKEIFIYNGMD
                     KYLLYTLLKELNANAH"
     gene            8713..8931
                     /locus_tag="RD451_002572"
                     /pseudo
     CDS             8713..8931
                     /locus_tag="RD451_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            9426..10025
                     /locus_tag="RD451_002573"
     CDS             9426..10025
                     /locus_tag="RD451_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016622858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDT7567782.1"
                     /translation="MKTVEPIRDKKKIDAMKAILASGKYGQRNLVLFSIGINTAYRIS
                     DLRQLKLADVLEISRGRVVVKDRLAMKEQKTAKHNSVYISNKLRKTILEYVQQEFPDQ
                     LLQQDFDGYLFPSRKGTNEPLNRQSLWRIIHDAGTAIGLKDIGPHSMRKTFGYFLYKQ
                     GTKTEIIQSLLNHSSQRETLRYIGITQEDKDTAVKSLDL"
     gene            10089..>10661
                     /locus_tag="RD451_002574"
     CDS             10089..>10661
                     /locus_tag="RD451_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriophage abortive infection AbiH family
                     protein"
                     /protein_id="HDT7567783.1"
                     /translation="MSTLYIIGNGFDLSHGLKTRYTDFSKWVEKSHSEIFDKIDTMIN
                     ENNEVRSTADDKIGWFNFESSLHELIQSPVFEDYVEESKDYLIGYGHEDWSDSAHHDF
                     QNMVYDYVVSLEELQQLFKEWIRKEIQPTIEHKIPKYQFSSDVLFFTFNYTDVLEILY
                     KQPKENIYHIHGSYDDIIIGHSENFDNFIGD"
BASE COUNT         3525 a         1674 c         1990 g         3472 t
ORIGIN      
        1 taggactcaa ttgttcatag atgagcattt gtaattaagt tatattataa taaaaaaata
       61 cgaattttag tgacgccatt atattgtttt tatttttcaa ttgtaatatt tcatattact
      121 tccataataa ggagtatttt ctattggaat atcttagctc ttttaaggat ttctcctttt
      181 ttgtttctca ttttttaaga ttatttggat ttcctttaca acaaacttcc acaagtatta
      241 ttgacataga tgtaattgag ggaagggggt tccagtgcta gaataaataa tgaaaagagg
      301 taacaaatgc tagcgttaag aggtgaacaa gtttgattga aagacatgta aatttattaa
      361 aattattaag tcgacaagaa gactttaaac ccgcttcttt ttttagtgat aaattggcag
      421 tgtcgaccaa gaccatttat caagatattg aattgttgga agattatgta gttaattacc
      481 aagtaacaat tgagcgatta ccttctttgg gtatcaaact cataggtgat aggaaaaacg
      541 ttgaacattt gatttcatcg gtagaaaatt atcttgaaaa agatatttat tctccagaaa
      601 aaagacgtgt cgagatcatt aaagaagttt tgtttggtga taagcctgtt tctttaactc
      661 atttgtctca aagttttatg gttagtaaaa catcgttata caatgacctg agaattatca
      721 ataaaattat tggcagtgga gaagttaagt tgcagtcatc tgcagaagga attagtttta
      781 ctggtaatga acaagcaatt caacgagcaa tcaagcaact tgtattctat tatgcgaatg
      841 acatggaatc aaaaacattt tttcaagttt taaatatgtt gtttgattca aaagttatta
      901 gtgtcattca tgatttgcta ttcaatgatt acagtgaact gactgaaaag gtttctgatt
      961 actatgttcg gtcattgatt tctactttag ttatccaatg taaccgttta ctgaaaggtc
     1021 atcatttaac tgttgaagaa gaattcctct tcaatagcat tcgctatatg gaaacgtaca
     1081 ttgtggcaaa tggtttaatt gaagaattga aggcaaaatt gaatcttcca ttttatgacg
     1141 cagataaaga atatctatgt cgtcaactat ttgcacatcg tgtgacaaat aatttaaaaa
     1201 ccagcaatga agagtacgct atgagcgttc ataaattgat tgaaagaatg agtgagattg
     1261 aaaaaattga tttgactcaa aatgatcgat tatatcaatc cttattgtat catgtgccag
     1321 caatggtcct tcgtttaaaa aaaggtatta aaattcaaaa tccgttatta gaaaatatca
     1381 aatctcaata ttcagaactc tttagcatag tatggtacgc catgtccatc cttgaagaag
     1441 aatttgatgt gactttaacg gacgatgaag tttccttaat tttgattcat tttcagattg
     1501 ctattgaaga tcagtccaaa gcaaataata tcatcattat ttgccaatac ggtatttctt
     1561 ctgcgcaatt aatttacaat aaagttcgac ggtttttacc agcaaaagat aatgtagaaa
     1621 tatcaacttt agataagttt catttagctg aaattgggga agttgatttg attatttcct
     1681 ctctttcctt tgatgcaggt ggtataccct tagtaagggt atctccattg gtaagtaaaa
     1741 cagattatat gaatattatg gaagcttata ctaaatattt aatagaagaa ccttcgcgat
     1801 ttattcaaaa tgaactgatt cctaaagcgg ttaaagttcc caccatatct aaatttgttc
     1861 aatcatcttt agtaaaaaca ggagtacagg tggaaagcaa agaagaatgt ttggatttga
     1921 tgatttccga actagaagcc aattcattag ttactgaaga gtttcgtgct tctatcttct
     1981 ctagagagaa aatggggaat actaatttag aaagtggtgt tgctttaccg catgcgaatc
     2041 catcaatggt cattgaatcc aacattttta ttgtagcatt aaaaaatgcg attaattggg
     2101 gcgatcgaaa agtcaaatta gtcattatgg ttagtttagc tgaagaagat gtatctgaga
     2161 ttagaggagt atatgaagaa ctttaccaat ttattgggca aaaagaaatg gtcgatcgct
     2221 tgttacaagt tcatgatagc gaaaaattac taagaatttt tcaacaaaaa ggagaataaa
     2281 aatgtatcta gataaagaat tatgtttatt tcaattagaa gtgaaagatc aaaaagaatt
     2341 gtttcaagta atgtctgaac aattaaaaaa cgctggttgc gtgaaagata gtttcttaga
     2401 aggtatcacc aaccgtgaac aagaatttcc aactggatta gaagtaaatc aaattgggtt
     2461 tgctatccca catacagatt ccgcacatgt aaatagctct caaatctgtt ttgcctcatt
     2521 aaaggaacca ctggtatttt cagatatgac agataaatct catgaaatac ctgtacgttt
     2581 agtctttatg ttggcaatgt cacaacctca tgaacaaatt gatacactac aaaacttagt
     2641 tagcctattt caaaatgaag aaaaagtaaa tgaattactt gcatgtacca cgaaagaagc
     2701 atttattgag ttagtacatt ctgcaggagt ttattaggag gaatagagag atggatattg
     2761 tattaaatgc ctttgaatgg tttattggat tagggtcaaa cgtcttttta ccactgatta
     2821 tttttgtaat cgggatatta tttggattaa aacctggtaa agcatttgtt tccggcgtta
     2881 ctgttggtat cggttctatt ggtttaggat tagttttaag tttattatca gatggtttag
     2941 gaacagcaat tcaacaaatg ggggaacaat acggtggtgg cctgaatatc ctagatattg
     3001 gcgtaggtgt tggtggacct ttggcttact ctacatcatt gggaatttta atgattccaa
     3061 tttcattaat tcttaacttc atatttgtgg ttttgggttg gacaaaaaca ttgaatgttg
     3121 atatttggaa cttttggttc gcaattttcc taggtatgat tactcaatct gttacgggaa
     3181 acttttggtt tggcttaatt ggcgcgattg tcgcagtaat tttacaatgg ttcttagcag
     3241 atcgtacaca aaaaactgtt agcgaatttt tcggctatcc aggaatctct atcacacata
     3301 tgatgggatt atcaggagta ctatttgcca aaccagtaaa ttgggttttt gatcgtattc
     3361 ctggatttaa taaaatagat gcagatgcag aaacattaac aaaacgtttc ggtgttttag
     3421 gtgacacagt tgttattggc ctaattatcg gtattgtagt gggtattatg gcaggctatg
     3481 acgtagcagg aattggaaac ttaggaatta tgactgcggc agtgatgaag attatgccta
     3541 aaatggtagc aatgtttatg gaaggtttaa tgccaattgc agaagcggcg aaagaattta
     3601 cgaataaaaa gttaaatggt cgccaagtaa acattggaat ggatgcagcg ttaactgtgg
     3661 gtcatccaac tattatgtca acttctctat tgcttgtacc aatctcatta ttgctagcac
     3721 taattcttcc aggaaataaa gtattacctt ttggagattt agcattcttt gctttcgcca
     3781 tctgtttaat gattccttat tttaaaggaa atattgtgag atcattagta ggatgttcgt
     3841 tgtatgttgt tacaacatta tatatggcaa catggttggc accaattatc actgatgtgt
     3901 ttacattagc aagtttcgat gtggggacag caggattagt aactatgttg ttatgtggat
     3961 tatggccagt agggttgttt gttttattag catcttactt tggtgtaatt ggaataggtg
     4021 gattaggagt tgttttagta ggtgcttcta tctacatgaa caaagtgaag aaagcttaat
     4081 cataaaatta aaataagaaa gaagagatca atatgaaaaa attattagtt atttgtggag
     4141 caggtcatgc tacttctaca attgcagtag caaaattatc aaaatggttg gaagaagaag
     4201 gattaacaga tcaagtgaaa atttatcaat ctaaaattgc tgatgagcta aataaaattg
     4261 atgaatatga tgctgtagta agtacaacaa ttgtccctga tgtaattaaa gctaaagtaa
     4321 cgaatggctt gggcttatta acaggtattg gtacagatgc catttatgca gatgtaaaag
     4381 aaagattagg tgtttaatat gcgttttcat catgacactt tgactattga aacagtttca
     4441 gggcgtcctt cgtatcatga tattcgaaaa gaacttttag atacagttga tacagcaggt
     4501 attgagaatg gaatgttagt aatttcgagc ccgcatacaa cttgctcact cttttttgaa
     4561 gaaacgatgc atgacacaaa cttttttggt gatgattatt tacatgtaga catcaacaat
     4621 gtaatggaaa cgattattcc aaaaatgacg agtgaaaatc aatacaacag tccggggcca
     4681 aaacacattg attttggaac aagattatct gatcccaatt accctgcaga aaaatgggtc
     4741 atgctaaata ccgatgcaca tttacgttca tctatttatg gaaccaactc aatgacttta
     4801 attgttcaag aaggtaaact tttattagga gaaatgggcc gtgtctattt tgtcgattgg
     4861 gatcaactaa gagagcgaac tagaacaatc aatctcatga ttatgggaga ataaacgggg
     4921 gaatagagaa tgacaattgc tccatcattg ttaaatgcac ctatcgcaga agttaaagag
     4981 ttatttgaaa tcttaaaaga aaagaatgtt gattatttgc atattgatgt aatggatggc
     5041 tgttttgtac cagatatggc ttttggacca agtgttatta aagatattcg tccactaaca
     5101 gacgttgtgt ttgatgttca tttgatgatt gatacaccag aaaaaattgt cacaagattt
     5161 gtagaagcag gagcagatat tgttaccttc cacattgaag ctaccaaaca cgcaatgaag
     5221 gtcattcagt tagtcaagga agcaggagca aaagtaggga ttacttttaa tcctgcaaca
     5281 ccagtcagtt ttattgaacc agtattatct ttagtcgatc aagtattagt aatgacaatc
     5341 aatccaggaa cagagaataa gcattttatt caagagacag tagttaaaat cgaacagtta
     5401 gatgtaatac gcaaacaaaa tgattatacg tatgatattg aagtagatgg caagattgat
     5461 aatcaaacga ttaaagtttg ttctaaagca ggggcggata tttttgtatc aggcggtttc
     5521 atcttcaatg ggaaaaatac cccgcaagaa caaattgata aactaaatca atcattagag
     5581 gaagtgaagt aaaagatcat gaccaataaa gaccaaaata aaaactattt agaagcgatt
     5641 atcttagaat tacaaaataa ctcaaaacgt attaattctg tagagttaga acaatttagt
     5701 gagaaaattg ttcaagctaa acacatcttt ctagctggtg caggacgctc tggaattgcc
     5761 atgcaagcat ttacgaatcg cttaatgcat ttaggttttt cagtcagcct tgtcggtgaa
     5821 attagttcac cacattcgca acctggagat ttattaatta tctgttctgg ctcaggtgaa
     5881 acaggtagtt taaaaaattt agcggccaaa gcaaatcaaa gtggtgtaag cattgcttta
     5941 gttaccatga aaaaagactc gtcgattggt caattagcag attctgttct tgtattacca
     6001 ggtattacca aagatgaaaa tcaacgagaa gaagatactt tttcacaacc tatgggttca
     6061 agttttgaac aattagcatt tctcaccttt gatagtttag tgttatcttt aatggataaa
     6121 acaggtgaaa gctcagaaac gatgtttgct cgacatgcag attttgagta gtagatttta
     6181 aagataaaaa accattctct aaatgctaat tattcagcaa atatgagaat ggttttttta
     6241 tttgattaga cataacttaa taattcagta gttttgagcg taagcgtgtc atagaatggt
     6301 acctaaacac aaatagcccg atttgataca ctcaaatcag gttatttgtg gcttatatta
     6361 tttacagatt tcttgtatct gctgattcca tggcaaataa gcgcgtagcg cttcaggtgt
     6421 catcgaagac agattgggaa tctctgtaaa aagatgattt aaatatttgc ggatgtttaa
     6481 cccattcgca acagctgtct ggataatact caatataatt ccatttgatc tagcgccttt
     6541 taagctttta gaaaatagcc agttttttcg accgatcact aactctttga tggcacgctc
     6601 tgctcggtta tttgaaagtt ccaagcgtcc atcaagcaac acaatctgaa gtccgtcttt
     6661 atgattgact gcgtattgaa ccgcctttcc aagctgcgat tttggcaaat aagcaaaact
     6721 ctcacaccaa tgaaaaaatt cagtcatcac aggctgcaac gtttccttcc tcgctacaaa
     6781 cctttcttct gcgctaagct tattaaaggt ccgttcgatt cgaaacatct tgtcacagaa
     6841 gtctaatcct attttggcat gactttttgg ggacggttgt ttacccaatg cttcaaaaaa
     6901 ctttctgcga acatgcgccc aacaataaac attgtttacc ggcagctttc cataggccgc
     6961 gtaaccatca gtatgcaaga aaccgctaaa tgattctaaa aaactttttg gctcatcaac
     7021 ggaacgcgaa tttgcgtgct cgtagagcac aacttgtttt tcttcgcttt tacctgaagc
     7081 atataaccag taaaaggtct tttctttatg agtattcaat acccgatagc ttgtctcatc
     7141 cgcgtgtaag acctcctgat tgcttaattc ttgatgaagg caattgtaga ttggctctaa
     7201 aaccatttca cttaccttga tatgccaatt agtgattttt ttacgatcaa gagggaaacc
     7261 aagtgcatgc cattcttttt cttgtcgata tgccggcacc tttttaacaa atttttccca
     7321 aatactctgt gtcacaattg aagaggaacc tagactatta ttgatcaacg gtttaggaac
     7381 aggcgctttt ttgatttttg tttctcctaa tgcttcacat tctctgcaat gataggcatg
     7441 ttggtagatg acttgttttt ctatatgggc aggaacatac aatggctctt ctctaagcct
     7501 tgtcgcaccg atatcatgta aagtatgacc acagtcttca cacaaacaat cggcaccttt
     7561 taattcataa tgaataggaa cttcaggcag accttctaat gaaagtgctt tgagtccctt
     7621 gcgttttctg cgtttaaaag aagataccgt aatgggttcc tggctttctt gtccagtgtg
     7681 ctctggttca ttaaaagttg agtcgtctaa taaatcgatt tgcccatcta cgggtggtgt
     7741 ttcttttttt cgtccaaaca agcgtcgatt catttcagca atttgttctc taagaagagt
     7801 attttcctgt tgctggattt caagcaactg tgttaattgc ttgatttgta caagaagttc
     7861 agattccatt tttgtcattt ttacaccacc attctagcga ttttcttaca tctattatac
     7921 cattttatga caacgaaaaa cagacaaaat ccttgattta acaaggtttt cgtctaatat
     7981 atcgcacctt ttttcgtttc ttttagcgta catttttctt cgattgaaag gccagtcagt
     8041 aagacttctt ttctggaacg cggccattga aggtacccac tttcaaatct tttgtacatt
     8101 aatacaaatc cattttgatc ctagtaaaga gccttgaagc gatctttctt cgtaccgcaa
     8161 aataagaaaa gcgcttgatc gtaaacatca aggtcatatt cttctataac gaaagctgct
     8221 agtccatcaa ttccttttcg aagatctgtt tttccacaaa cgataaaaat atgtttcaat
     8281 gcagttgcat caatgagcat tggcattcaa ctcttttaac aaggtataca aaagatattt
     8341 atccattcca ttataaataa atatttcctt atcttccgat ttgattctgc aagctagttt
     8401 tggcttggtg tcaatttgcg atttttgagc cgcacttgaa aattgaactg gtacaatatc
     8461 ttttttattc attcgttttt ctccttctat atttgatagt ttaattatag aagaaagata
     8521 atcggcgtac gagatactat cctatgacac gcttacattt aatttaatat tttgcctcaa
     8581 attagccaca ctttttatag aactaagagg aaaaatgaag ttttcttcct attaatatag
     8641 ttgtttgaaa tcttaaatat agcgttttac gatgtaatgg gaagtatggt gaataaatca
     8701 actatgttcg tacgaagcat ttactcaact aatttaatcg aatctttcaa taaacaaatc
     8761 aagaaataca gccaccgcaa ggaacagttc caaaatgaag agtcgatgga acgtttctta
     8821 gtctcgtctt ttgatactta caaccaaaaa ttcctaggtc gcagtcataa aggtttccaa
     8881 caggccgaag gcgagctcga acaaatgctg agtcaaccga tggagaatta gaaacaatct
     8941 acagtaggga agaaccattg acacaaaatt attgacgctc ccaactaaaa gtgtcaaaat
     9001 aatgatgaaa tcatttagtt cttataaatt agaaaagaga aaataaatat tccatatcta
     9061 ctttattgga tccgtaacat gactaaattc tgaatacttt ttaaagctta tcatttggta
     9121 aaactgaata taagttaatt atatagactg aaaattttga attttcagaa tagaataact
     9181 taaaagtact gacaaaattt tttaaagggg caatattaat gttctgagat aatcaaatcc
     9241 taccgaaaat atcaaaaatc caatgtgaca caatcagatt gtgtctcatt cgagggaatc
     9301 acacaatccc acgtggctct aggcagaatt gaatttttgc ttggggcttt ttccttatat
     9361 tgattttgaa tgagacttat tatatgttat aatgcaatta agtatcattg gagagggcga
     9421 agaaaatgaa gacggtagaa cctattcgag acaaaaaaaa gatcgatgcg atgaaggcaa
     9481 tcttggcttc gggaaaatat ggccaacgaa atttggttct tttttcgatt gggatcaaca
     9541 ccgcctatcg catttctgat ttgcgtcaat tgaagctggc cgacgtgctg gaaatttcac
     9601 gcggtcgcgt ggtggtcaaa gatcgattag cgatgaagga acaaaaaaca gctaaacata
     9661 attcggtcta tatttccaac aaattgcgaa aaacgatttt ggagtacgtt caacaggaat
     9721 ttcctgatca actccttcag caagattttg acggttattt gttccctagt cgaaaaggga
     9781 cgaatgaacc gctcaaccgc caaagtctgt ggcgaatcat tcatgatgct ggcacggcaa
     9841 tcggattgaa agacattggc ccacattcca tgcgaaaaac gttcggttac tttctctata
     9901 aacaggggac caaaacagaa atcattcagt ccttgttgaa ccattcttct cagcgcgaaa
     9961 cattgcggta tattggtatt acacaagaag acaaagatac agctgtaaaa agcttagatt
    10021 tataatataa aagttaagtt taaacatgga tagttttaaa ttagtagatt gagtgttggg
    10081 aggaaagaat gagtacatta tatattatag gaaacggttt tgatttaagt catggtttaa
    10141 aaactagata cactgatttt tcaaaatggg ttgaaaaaag tcatagtgaa atattcgata
    10201 aaatagacac aatgataaat gaaaataatg aggtgagaag tacagctgat gataagatag
    10261 gttggtttaa ttttgaaagt agtttgcatg agttaattca aagtccagtc tttgaagatt
    10321 atgtagaaga gtctaaggat tatctcatag gttatggaca tgaagattgg tcagattctg
    10381 cccatcatga ttttcaaaat atggtttatg attatgttgt ttctctagaa gaattacaac
    10441 aacttttcaa ggaatggata cgcaaagaaa tacagccgac aatagaacat aaaattccaa
    10501 aataccaatt ttcgtccgat gtactattct ttacattcaa ttatacagat gttttggaaa
    10561 ttctatacaa gcaaccgaaa gaaaacatat atcatattca tggcagttat gacgatataa
    10621 taatcggcca ctccgagaat tttgacaact ttataggaga t
//
LOCUS       DAPBAF010000072        10035 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.074, whole genome shotgun sequence.
ACCESSION   DAPBAF010000072 DAPBAF010000000
VERSION     DAPBAF010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10035
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.074"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(499..723)
                     /locus_tag="RD451_002575"
     CDS             complement(499..723)
                     /locus_tag="RD451_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567784.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            914..3691
                     /locus_tag="RD451_002576"
     CDS             914..3691
                     /locus_tag="RD451_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDT7567785.1"
                     /translation="MNKLLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNT
                     VSHYLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQP
                     KDLFSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLH
                     DLLEDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLD
                     EVHRLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRI
                     PIRIELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGEL
                     KNIVKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLM
                     EKQQPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHEL
                     LVYWTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELE
                     QQVSQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIA
                     AHGYATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILV
                     DMGSLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPE
                     WRLLYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNS
                     DPLFSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQ
                     RIIRNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLI
                     ERLIRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSE
                     DTEFLSIEEEF"
     gene            3772..4191
                     /locus_tag="RD451_002577"
     CDS             3772..4191
                     /locus_tag="RD451_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HDT7567786.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            4203..4673
                     /locus_tag="RD451_002578"
     CDS             4203..4673
                     /locus_tag="RD451_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDT7567787.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            4690..5469
                     /locus_tag="RD451_002579"
     CDS             4690..5469
                     /locus_tag="RD451_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDT7567788.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            5456..6277
                     /locus_tag="RD451_002580"
     CDS             5456..6277
                     /locus_tag="RD451_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDT7567789.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            6294..7343
                     /locus_tag="RD451_002581"
     CDS             6294..7343
                     /locus_tag="RD451_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDT7567790.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            7356..8360
                     /locus_tag="RD451_002582"
     CDS             7356..8360
                     /locus_tag="RD451_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDT7567791.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            8993..10012
                     /locus_tag="RD451_002583"
     CDS             8993..10012
                     /locus_tag="RD451_002583"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HDT7567792.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
BASE COUNT         3363 a         1653 c         2094 g         2925 t
ORIGIN      
        1 tttacttctt ttttaatttg ttcttgcaat cttttttgct acgtaatttt tgtaaaaaag
       61 tgggttgaga gaaatctaat tgattttcaa agaaggagta tgaaaatgag aaaaatattt
      121 attcgtttat tgtgggtact atcttagagg aataaataat agtggagaaa actatggttt
      181 ggcgcagatt ctatcaggtt tgatggaacg aagacaacct cccgacatca agtcaaaagc
      241 tacttgagat tttgatctga aaataaaaaa agaaaacaag gtaggaacat caatgtttct
      301 accttgtttt cgtaatcaat gggaaaaaac taagagtggt gtacgtaatc aataaaaagg
      361 atggtgacaa cagtacctct ttactctctg aaagcatcat aactcgtttt tcctcattat
      421 gccaataaat tgttgttata ccacatataa ggatttgtaa tagctaaaaa cagacaggaa
      481 agttgaaatc tgtgaatctt attttgtatg gaaggattta tagaacgcaa aaatcaagat
      541 aaagatgaat aaaaatcctg tttcggctat atattgcgta tctacgccaa taaaacgagt
      601 ttgttctgtc atagccatat aaagcaaagg caaaaataca actacagcga gataagatcc
      661 gatgatttct cgaaaagttt tccaggaagt atgtttcctg tttttatatt tatccgattt
      721 cattgaatag tcatagcctc cttattcttt catatgttga aattccagta taaaaactgg
      781 aaggaactgt acgtttttta gaataaaaat tataagggat aagtaggctg ctgtctataa
      841 taagatatat ttttcaattc tttattaaag attttattga caaaatgaat ccgttttcta
      901 tgatggagga ggggtgaata agttgttgaa gaaggaaatt ttatgttact tagagaacca
      961 gacagccttt ttcgatttag aacatatgaa cgaggtcttt acagcacaaa ggttagctga
     1021 tcattttggg gtaaaaagaa acacagtcag tcattatttg aaccagttaa atgatgagca
     1081 actactagtc aaaatcaatt ctcgaccagt gatttatttc cacaaagaag cttttgaaaa
     1141 acaatttttt aagttacgca cgaattttta tttttctatc gatgatctca aagaggaaca
     1201 gccttttttc gcgcaaccaa aagacttatt ctcttttatg atcggatacg acgccagttt
     1261 gaaagaaagt atcgaacaaa tcaaaacagc tctttactat ccagatggcg gattaccact
     1321 tttgattaca ggcgaaagtg gcacaggtaa aagttattta gttaatttgg tctatcagta
     1381 ttgtctgctt catgatctgc tagaagattc tgcaccattc atcactttta attgtgcaca
     1441 atatgcagat aatcctgaac ttttgactag caatttgttt ggacatgtta agggagcgta
     1501 cactggtgca gaagaaaata aaaaaggggc ttttgaagca gcagatggtg ggatcttgtt
     1561 tttagacgag gtacatcgct taacaccaga aggtcaggaa aaactgttca cctatcttga
     1621 tcaaggtgtg atttatcgta tgggagaacc taatttgtca cgccggatca aaacacgtct
     1681 cttttttgct acgactgaag agattactag tcatttctta acaactttca ttcgaagaat
     1741 acctatccga atcgaactac ctgcacttaa tcagcgtagt cgtaatgaac ggctagaact
     1801 gatttactct ttttttctcg aagaacaaag aaaaatgggg agccctttgt cagtcagtgg
     1861 accagctttg tcacttttaa caagtcagaa attatccgga aacataggag agctgaaaaa
     1921 tatcgtcaaa gtttcagcag caaaagcata tgctgaacag cgtgaacagc ctgaaatcca
     1981 tgtcacgatc catcatttgc aaaaagaact acttgcgcag cctattacta aaaatacagc
     2041 acagcaagga atctatatta cgcaagacca gaccttagag caattaatgg agaagcaaca
     2101 gcccgaacag cagcgaatcg ttaaaagttt tgagcaaatc ctaattgatt tcaagaaaaa
     2161 taactgtctg ctatattctt gcgaaggaaa attaaagcaa gaagtgattc aattatttga
     2221 ttttttgctg tttgagacca gtagacaaga aaaacacgag ctgctggttt attggacaca
     2281 atctatccga gagacctttc gacaaatgga aactgcctat caaatcaaat tcgatggaaa
     2341 cagtgtctat gccttgagtt actatctcta tcagcgaagc actatcaaat ggttaccgga
     2401 agaacatgat attatccaac taatcaaaga attagaacaa caagtttctc agtcttatcc
     2461 atctagttat cactatgtcc aacgaattct ggaattaagt aagatcaaat tagatattga
     2521 agacacaagt atggatcgga ttttactgac gatctatcta aaaaaagcga aatggtcaaa
     2581 agaaaaacga ctgccaaaag cgatgattgc tgctcacggt tatgcaactg ctagcagtat
     2641 ggcaaatgta gtaaatcgtt tattacaaga ggatctattt gaatcatttg atatgccact
     2701 agatgtcaca ccacagcaga ttgcttcaga aatccttgat tattgcgaaa acagcgatgt
     2761 ttcaaatgga ttgatcatat tagtagacat gggatctctg aaagaaatcc atcagttttt
     2821 taaaaaacag ttatccgtac cgcttttgat tttgaataat gtgacgacac ctttagcaat
     2881 cacagtaggg gaatgcctgc aaaaaaatgt atcattagaa gagatagcag aagagactgt
     2941 tcgacagatc cagccagaat ggcgactgct ctatccagag gaaaacaaac ccaaagcact
     3001 cattactact tgcttcactg gaatcggtac ggcggtccac ttaagtgaac tgctagaaaa
     3061 aagcttacct acggcttgtc agttgaaaat catcccatat gaatatcagc aattaaaaga
     3121 taagaaaaac agtgacccat tattttccat atacgaagtc gtaggaatga ttggcaccac
     3181 agatcctgat atcaccaata tcgactatct ttcattagaa gacctcatct cgggggaaaa
     3241 gatgtctgta ctagctgaat ggttggacac tactatgaat gcttcagaga aggaaatatt
     3301 caatcagcgc atcattcgta atttttcatt ggaaaaagta ctggattccg tgactattct
     3361 agatacagag aaggtgatgg gagaaatcga tcattttatg agagaattag aggtgcagtt
     3421 gaatcgaagc atcagcaatc ccaaaaaatt agcgttgtat gtccatgtga gctgtctcat
     3481 tgaacgattg atccgacaaa tgccaatcga aacctatcaa ggattagaga aatggaagca
     3541 gtgtcaaaaa gaagggttat ctgctattaa atctgcgttt agtgtcattg aagagcatta
     3601 tagtgtcatg atccccaatt ctgagattgc ctatatctat gatattttga gtgaagatac
     3661 agagtttctc tcgatagaag aagaattttg aacataagca agttgttgcc actaattttg
     3721 gcatgcaact tgctttttta gtatgtgtaa gtgaaaagag gagatgaaaa agtggataga
     3781 gaaattatct tagcttccca tggaaaattt gcttcaggga tattagattc attagagctg
     3841 atctatggga aaaatcattc tattactgta ttcgattgct atactgatga gaattttgat
     3901 ttagcggaaa cagtaaggca gctttttatg aggtacaaag ataaagaaat cattgttctg
     3961 acggatcttt ttggcggaag tgtcaacaac gaattcttac aatatatcaa tcgggatcat
     4021 gtctatctcg ttgccggatt gaatttgcca ctattgattg agctagtatc tcggttggac
     4081 gctgaagtag agacaactgt tttgatccag caggtgctaa ctgattcaaa aaaaatgatc
     4141 cagttttgta acgagcggct caatcagaaa atagaagaag acgaatttta ggaggaagaa
     4201 aaatgattgt attgacaaga gtcgaccatc ggttattaca cggacaagta gctttttcat
     4261 ggacacaaac aataggcgca gactgtattt tgattgctaa tgatgatgta cctacgaatg
     4321 agatacgaaa gacaacgatc aaattagcca agccacaagg agtcaaacta gtgatcaaat
     4381 caattgatga ctcgattgcc gcgttgaaaa gcggggtgac agataaatat aagttattca
     4441 tcgtagtgga atcgatcgag gatgcatata agctggcaga agcgtatcca gaaatcaaaa
     4501 ccatcaactt aggagggatc aaggcaaaac ctggtactcg cagcatcgga aaagcggtaa
     4561 atattttacc agaagaggag gaacgcttga aacgattaat tgacaaacaa atagaagtag
     4621 aaatccgtca agtaccagca gataaaaaag tggatgtaag agaagttttg taagaaagga
     4681 agaacctcaa tgattgtaca agcagtctta ttaggaattg ttgcatttgt cgcacaatca
     4741 gaatatgcac tagggacatc gttgctttct cgtccgattg tgacggggct gtttacagga
     4801 atcgtgttag gtgatgtaaa aactgggatc attatgggcg caactttaga gttagcattt
     4861 atcggatcgt tctcagtagg tgcttcgatt ccacctgatg ttgtgaccgg tgggatttta
     4921 gggacggctt ttgctattac agctggagcc ggtacagaaa ccgcgctttt actaggtttg
     4981 ccgattgcta cgttgacatt gatattgaaa aatatttact tagggctttt gattccaatt
     5041 atgaaccata aagcagacaa ttatgcagaa gaaggaaatt ataaaggagt cgagcatatg
     5101 cacttgcttg ccggtatcgg tctttccttg atgcttggtg ttgtggtaat ggtttcttat
     5161 atggtgggaa gcaatacgat cggaaatcta ttaaatatga ttcctgactt cgttcaaaag
     5221 gggttgtcag tagctacagg gttgattcca gctcttggtt ttgcgatgct tgctcgtttg
     5281 ctgatcaaca aacaagttgc accatatttt ttcttaggtt ttgctatagc ttcttactta
     5341 gagattcctg tgaccggagt agctattttt ggtgcgattt tagcagttgt ggtagtcaat
     5401 attatgaatg tccgtcaact accacttcaa acaactgcag gggaggtaga agaagatgaa
     5461 gaattctgag atcaaaaaca gcaaaataac gaaaaaagag ctaaatcacg tattttggcg
     5521 ttcttttcaa atggagtttt cttggaatta tgaacgtcag atgaatatgg cttatgttta
     5581 tgcaatgatt ccgattttga aaaagttata tcagtcgaaa gaagaaatgg cagcagcttt
     5641 gaaacggcat ctagagtttt ttaacacgac cccacatatc gttacactga ttttaggaat
     5701 cacggctgca atggaggaag aaaataagga tgatcctgaa tttgatgtga ctgcgatcga
     5761 tagtatcaaa acatctttga tgggacctct tgcagggtta ggagattctt tcttttgggg
     5821 aactttgcga ttgattgcca caggtgtggg tacctcttta gccatgcaag gaaatatttt
     5881 aggccctatc ttgttcattt tgattttcaa tattccgcac attctgtttc gctatctagc
     5941 aacaggttgg ggatatcgct taggaacggg ttttttgaaa aagatccagg caaacggtat
     6001 gatggaaagt ttgacattag gcgcgtctat tattggactg atggtcgttg gagcaatgac
     6061 tgccacgatg atcaccatca atattccttt aaaaatcggt tcaggagaaa atgctgtgac
     6121 tgttcaaagt atttttgatg atatcgttcc aaatatctta tgtcttggag catttggcat
     6181 agtgttttat ctattgaaga aagaagtgaa accattaacg atcttgatcg gactagcttt
     6241 ctttggaatt tttggttcgt ggatagggat tttttaaaaa aggagcagag aaaatgttta
     6301 cgatgcaaga ttatatctat gaagaaaagg aagtactaag tacgatcttg aaaaagaatg
     6361 atttttcgac aagagaacat atgaaaaaaa cagtgaattt actgatctta gcaacgggtt
     6421 catcttataa cgcttgttta gcagcgaagc cagcattgga atcttatggt gatcttactg
     6481 tcgatattca agaacctttt tattttttca attatggaaa actttctcct tcaatcgata
     6541 ctgtgattgc tgtgtcacaa agcgggaaaa gtgcttctac tgttgaagca gtaaaaatga
     6601 tacaaaaaca agggttacct gttgttgcta tcacaaatga cgtgcaaagt ccacttgctt
     6661 tagaagctgc acaaattatt gatttaggtg ccggggtaga atcagtaggc ttcgttacaa
     6721 aaggctattc tgcgactgtt ttacagttac tactcttagg gataggaatt ggaataagta
     6781 aaaataaaat cagcaaaaaa atagaacaag actacatgca acagttgcgc aaaataatca
     6841 accatttacc agcgattatt caaaaaacgg aagaattttt tgatggatat caaagtttat
     6901 ttcgtttagc acagcgtttc gtcaccattg gatatggtcc aaactgggga acagctaaag
     6961 aagcagagac gaaattgact gaaacaatcc gcgttccgtc acaaggattt gagttagaag
     7021 cttatatgca cggcccatac ctggaggcag atgcttcgca tttgctattc tttattgaag
     7081 gggaaagtgt aaataaggaa cgttcgcaaa agttgcaaag atatatgagt cggtacgttg
     7141 gagagactct caccattacc acaaaaaaag caagaaacga gaaaacactt ggattagcaa
     7201 tagaatgtga tgaatatctg tctgtattag cgcttgtcgt tccgtttcaa ctattcgctt
     7261 ataaaaccgc agtagctaaa ggtattgact tgaacaaaaa gatttttgaa gactttgata
     7321 cagtcttgaa aagtaaatta taagaggtgg aaatcatgct gaaattcaat gaagaagaac
     7381 aaatcaaagc aataaaaggc gcactagctt tacgtccgca agtagaagaa atcatcgata
     7441 aactttatgc ggaaaaattt gacgctgtct attatctagg aatcggtgga acgtatgctt
     7501 cctcgatgca agctgtcact tatatgaatg ggaaaagcaa cttgcctgtc tttgtacagc
     7561 atgctgcaga atattacact actggaaaca aaagattaac aaaagattct atcgttattt
     7621 tgtcctctgt taccggtaca actcaagaag tagtgaaagc agtagaacaa atcaagaaag
     7681 taggagcgac actgattgga tttatcgata aagcgaacag taagttgtct cagctatgcg
     7741 attttgtggt cacttatcca gctcctggaa cagaacaaat caaatttttt atggcagcag
     7801 atcgattgat gtatttgaat ggagaattcg aagcttattc agaatactat gaacagctcg
     7861 aacgttattt accaacaggg ttagtggaag cagagaaaaa agcagatgca tttggcttat
     7921 catttgcaga aaaacatcga cgtgatagta tgcattattt tattggagca gggaatcaat
     7981 ggggagctgt ttattcatat gccatgtgtt actgggaaga acaaagctgg cttccatcga
     8041 aatctatcca tgctgccgag tttcttcacg ggacgttaga gatcgtagaa gaaacaaccc
     8101 cagtcacatt atttttaggc gaagatgaac agagagtgtt atctgaacgt gtggctaaac
     8161 ttttgccaaa aatttgcagc aattatacat tgatagacac aaaagactat ccagtagaag
     8221 gtatcagtga aaaatatcgc ggacgtgttt tgtctttctt attgatgcat gtagtgacac
     8281 aacgcatcga tgctcatgtg gagcagttga actgccatcc attagagata cgccgctact
     8341 atcgtcagtt tgattattag gatagactgg ataaaaagaa tataaaaaat aaagagagca
     8401 gcgataactg ctccctttat ttttttaaaa tattggcatc aattacgtta taaaacacat
     8461 tttttgcatt atctacagtt caacttataa tctgtttaat gggacatgtg ggtgccaacc
     8521 attttttgtt atgcaatagt actatttagt tgttgcatgg atccgtagta aaagtccaag
     8581 tacaacgagt tgcgccagtt tacatagcgt tttgtatcca gaatgttgac taaaacaaaa
     8641 gttcctatgt caaccgtcaa cagagacaat ctgtccgttg caggacctga cagatttaga
     8701 aatgttcaat ctgtctctta tgtattttaa atcaatactc actaggagaa gtttcctaac
     8761 ctcctaatag taatgctggt agtaacattg tcaaaactgc ttcctcttag gaacaagcaa
     8821 agcataacga gtgtaaaaat aaaatgtaga ctattgtaac atatcattga ttatttcaag
     8881 taaaaacgat aaaagaagta aacaaacact taaaaacaat ggaaattagt cccaacttta
     8941 agaaatgtat actataatgg aaattatcaa ttatttattt ggaggaatat ccatgaaaca
     9001 aaaaatcgca gttcttggtc ctggatcttg gggcactgct ttagcacaaa cattggcaga
     9061 aaacgggcat gatgtccgta tttggggaaa tgtacctgaa cagattgatg aaatcaataa
     9121 gtatcataca aatcagcatt ttttacctga tttgacgatc ccagaatcga ttatcggata
     9181 taaagaattg gcagaagcag tggataacgc agatgctatt ttatttgttg ttccaacaaa
     9241 agcgattcgt tcagtcgcac aggaacttat tggtaaaatg aatactaagc caatcattat
     9301 acatgcaagt aaaggactag aacaagatac gcataaacga atctcagaag ttttggctga
     9361 agaaattcca gaagaaaaaa gacaggcaat tgttgtatta tctggtccta gccatgctga
     9421 ggaagtggca gtacatgata tcacaacaat tacagctgca agtattgatc aaaaagcagc
     9481 agcctatgta caaaaactgt tcatgaatga ttatttcagg atttatacaa ataatgatgt
     9541 gattggcgta gaaactggtg cagcactgaa aaatatcatt gcaattggtg ccggcgctat
     9601 ccatggatta ggattcggag atgatgcaaa agcagcaatc atgactcgag gattggcaga
     9661 aatcagccgt cttggtgtcg cgatgggtgc caatcctctg acatttatcg gtttgagtgg
     9721 tgtgggggac ttgatcgtta cttgtacaag tgttcattct cgcaattggc gtgccggtaa
     9781 cttgttagga cagggacata agctggaaga agttctagaa aacatgggaa tggtcgttga
     9841 gggtgtggca acgacaaaag cagcagtaga gctagctcaa cagctaggtg ttgagatgcc
     9901 aattactcaa acaatctata atgttttgta taatggagaa gatatcaaaa aagcagcaaa
     9961 agaaatcatg ttacgtgacg gaaaaatgga gaatgaattt tctcttcgtt aaatagatga
    10021 tcaatagtta atcgt
//
LOCUS       DAPBAF010000073         9699 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.075, whole genome shotgun sequence.
ACCESSION   DAPBAF010000073 DAPBAF010000000
VERSION     DAPBAF010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9699)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9699)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9699
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.075"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            <1..1023
                     /locus_tag="RD451_002584"
     CDS             <1..1023
                     /locus_tag="RD451_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HDT7567793.1"
                     /translation="ELKPKHERQNFLVGDDRLDHAVAFLWKDPQTGETVGASYQGTIV
                     DFNRFGKRGTYKHIDKNPTPNHGFNLKIGDPKHLKFFESSIDLLSYAALNREKLQDAW
                     LVSMDGLKHHVISHYVEESISELRRKQTFPQSIEICVDNDRAGHIFYEKEQMKGIVDP
                     FTNKKIRCERGIPNDWQVPKEYKATYEAVAKEMSVEPEAIMAIHKTETNLQLTNQLVS
                     AHDVQSTFGKMLAKGEPVETIDLKEACTTVAKELKVCERADGTYNFDRFYSRKANIKD
                     VNAGILLSYKAEQYYKGYKKHEHEFVPEVKKDWNDQLKHEIQQQEIRKQKRAMLFQQG
                     RQQERE"
     gene            1034..3043
                     /gene="topB"
                     /locus_tag="RD451_002585"
     CDS             1034..3043
                     /gene="topB"
                     /locus_tag="RD451_002585"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HDT7567794.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFTGETVIT
                     YGFGHLVELDSPDMYDEKWKQWALEHLPIFPNQYHYHVPKDKKKQFSVVKRQLQSADT
                     IVIATDSDREGELIAWSIIQQAGANQGKTFKRLWINSLEKEAIYQGFQQLRDAEETYP
                     KFEEVQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FQKEPYFEGKAQVIAQNGAFDAKLDPNETQATQEAFEAYLKEKGVQLGKQPGTILQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLKAEAIPTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTAAAFEQ
                     LSPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAIEKVPLDLGWKKLFGK
                     ESDGKEKEEEPLLPKVTKGEMVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGILLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGERKGTQTTFLANIQKFVSHLLEVVPGQIQSTDFGSTLQEVKA
                     ASEKQEAARHLGICPKCQEQEVLLYQKVAACTSEACDFKRSEGFI"
     gene            3159..3308
                     /locus_tag="RD451_002586"
     CDS             3159..3308
                     /locus_tag="RD451_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567795.1"
                     /translation="MRNTTHKQQEIENQKAKIRSEQEKMRASKRRLQQLKNQQRIQKE
                     IELDR"
     gene            3389..3985
                     /locus_tag="RD451_002587"
     CDS             3389..3985
                     /locus_tag="RD451_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HDT7567796.1"
                     /translation="MTKAMVYKLLEEFNGTLALKDAKKAGISPVTIKRMVDRGELDRE
                     YPGFFTLPGQFPDELFMAQKKYERGIISHITALDLYDLTDMIPRQIDLTVPYGYHVSE
                     KGLKEFAVELHYTKAEWYELGKIEIKSRYGNPIIAYDPERTLCDIWNPWYTVEDEIKV
                     KAIKNYMESDRKNLRKLNEYRRILPTDKTMRSYIMALN"
     gene            3998..4897
                     /locus_tag="RD451_002588"
     CDS             3998..4897
                     /locus_tag="RD451_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HDT7567797.1"
                     /translation="MTPTQLKAKVKNISREKEVDPQLVLRHFMMEKFLEKISESPYRE
                     NFVLKGGFLIGSKYGIENRTTKDIDTTLREMKVTKETLTTVLNEIFSTPTKEGIQFEI
                     QGMKETREADYYPGFSLRVLAHLENMRPDFKVDVTTGDSIYPATITHSHKLMFEDRTI
                     PLESYPTEQIIAEKLSATFDFLTDNSRGKDFYDLYTIPKMEKIDEKTLKDSVRNTFTR
                     RGKTDPLKIYYEKDMDVLKNSHELKDTWKKYQKSNPYAASITYDETMDSISNLMEKVI
                     HVEEKERKLAYQRHQQMNREMER"
     gene            4900..5031
                     /gene="ssb"
                     /locus_tag="RD451_002589"
     CDS             4900..5031
                     /gene="ssb"
                     /locus_tag="RD451_002589"
                     /inference="COORDINATES: protein motif:HMM:TIGR00621.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDT7567798.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQNGN"
     gene            5053..5385
                     /gene="ssb"
                     /locus_tag="RD451_002590"
     CDS             5053..5385
                     /gene="ssb"
                     /locus_tag="RD451_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDT7567799.1"
                     /translation="MIWRKPAETMATLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEV
                     VADNFQLLESKAATESRAHADQSSTSPSTATFEQRNTATPNNNGLNASQNPFGGQSID
                     ISDDDLPF"
     gene            5407..5664
                     /locus_tag="RD451_002591"
     CDS             5407..5664
                     /locus_tag="RD451_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567800.1"
                     /translation="MAKKISLTMDLLIPVIAFIDGISLGVTENPLVNRIAKGSLFLVF
                     VYLVCSYLLKRAGKDNSFWRLTKVTVAATAVILTAILPLYM"
     gene            complement(5823..5945)
                     /locus_tag="RD451_002592"
     CDS             complement(5823..5945)
                     /locus_tag="RD451_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002389461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HDT7567801.1"
                     /translation="MKGVSLLSAYETIQTILGFGMFTIALISLIVNMLKNDKKK"
     gene            6135..6359
                     /locus_tag="RD451_002593"
     CDS             6135..6359
                     /locus_tag="RD451_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567802.1"
                     /translation="MIKTQPLLVRFTLRTSHEPINCVVANIEIADKLLILEEGKYTIS
                     VTGHFNKRKQLVIESMQIRNPDHFTRSMSI"
     gene            6802..7008
                     /locus_tag="RD451_002594"
     CDS             6802..7008
                     /locus_tag="RD451_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HDT7567803.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGERAKCIKSYCLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            7008..7259
                     /locus_tag="RD451_002595"
     CDS             7008..7259
                     /locus_tag="RD451_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567804.1"
                     /translation="MKTQHKLLTVKEVVQILVDKEVISEKVAEVLLIPRYWTIETPLV
                     EDAPTMLFEDLVKIAGYELHYQENLETYENEYWLTKLEN"
     gene            7274..7429
                     /locus_tag="RD451_002596"
     CDS             7274..7429
                     /locus_tag="RD451_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567805.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYNETRVPKKHYKEKLSV
                     AVEEMIE"
     gene            7439..7711
                     /locus_tag="RD451_002597"
     CDS             7439..7711
                     /locus_tag="RD451_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567806.1"
                     /translation="MNLIATYYRTLEELKKQNAKWFFQALLCLEVGVKPSTIKPSEYQ
                     ALELTYAKFIETKKAKTVSSEWLDYFENINKYGAYYTMKKEDNENE"
     gene            8156..8335
                     /locus_tag="RD451_002598"
     CDS             8156..8335
                     /locus_tag="RD451_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567807.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESKIMCIALDLL
                     IAQEKAGFDVPALKK"
     gene            8394..8750
                     /locus_tag="RD451_002599"
     CDS             8394..8750
                     /locus_tag="RD451_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567808.1"
                     /translation="MLKTKKNSYKLKLSILSIICLLGMIISGHLYRVAYTQFIEYKVH
                     SLGLAGDRYVEYVHYSLKCSSYILLWLIFSLFELLNLIAISSYHLDKLNTKSSRYNEV
                     FKENVKLESDLNKLKK"
BASE COUNT         3486 a         1614 c         1993 g         2606 t
ORIGIN      
        1 gaactaaagc cgaaacatga acggcaaaat tttttagttg gagacgaccg tttagatcat
       61 gcggttgctt ttttatggaa agatccacag acaggagaga cagtaggggc aagttatcaa
      121 ggaacgatcg tcgattttaa tcgtttcggt aaacggggaa cgtataaaca cattgacaag
      181 aatcctacgc caaatcacgg atttaattta aaaataggcg atccgaagca tttaaaattc
      241 tttgaaagta gtattgatct gttaagttac gctgcattga atcgggagaa actacaagat
      301 gcctggttag tttcgatgga cgggttaaaa catcatgtaa tcagtcatta cgttgaagag
      361 tcgatttctg aattaagacg aaaacaaaca tttcctcaat cgattgaaat atgtgtggac
      421 aatgatcgtg caggacatat tttttatgaa aaagaacaga tgaagggaat cgttgatcct
      481 tttaccaata agaaaatccg ttgtgagcga ggaattccaa atgattggca agtacctaaa
      541 gaatacaaag ctacttatga agcagtcgca aaagaaatga gtgttgaacc tgaagcaatt
      601 atggccatac acaaaactga aactaattta cagctgacaa atcaattggt gtctgctcat
      661 gatgttcaat ctacgtttgg aaagatgttg gcgaagggcg aaccagtaga aacaattgat
      721 ttgaaagaag catgtaccac ggtcgcgaag gaactgaaag tatgtgaacg cgcagatgga
      781 acatacaact ttgatcgttt ttatagtaga aaagccaaca taaaagacgt taatgcagga
      841 atccttcttt cctataaagc agaacaatac tacaaaggct ataaaaagca tgaacatgaa
      901 tttgtacctg aagtgaaaaa ggattggaat gatcaattga agcatgagat ccagcaacaa
      961 gaaatcagaa agcaaaaacg tgcgatgttg tttcaacaag gcagacaaca agaaagggag
     1021 tgaagtcgtc actatgaaaa ccgtcatttt agcagaaaaa ccgtcacaag cgaaggctta
     1081 tgccgatagc ttttctaaag ctacccgaaa agatgggtat tttgagatcc aagatcgatt
     1141 gtttacagga gaaactgtga tcacgtatgg ttttggtcat ttagtcgagt tagattcgcc
     1201 cgatatgtac gatgaaaaat ggaaacaatg ggcattagaa catttgccta ttttccccaa
     1261 tcaataccac tatcatgttc ctaaagataa gaaaaagcag tttagtgtcg tcaaacgaca
     1321 gctgcagtca gctgatacga ttgtgatcgc gactgatagc gatcgtgaag gggagctgat
     1381 tgcctggtca atcattcaac aagcaggcgc caatcaagga aaaaccttta aaagactttg
     1441 gatcaactcc ttagaaaaag aagccattta tcagggattc caacagttac gagacgcaga
     1501 agagacctat ccaaaatttg aagaagtaca agcacgtcag atcgccgatt ggttaattgg
     1561 gatgaacggt agcccactgt atagtttact cttgcagcaa aaaggcatac caggaagttt
     1621 ttctttaggt agagtccaaa ccccaacact ctatatgatt tatcaattgc aggaaaagat
     1681 tagaaacttc caaaaagaac catattttga aggaaaagcc caagtaatcg ctcaaaatgg
     1741 cgcatttgat gcgaagcttg atccaaatga aacccaagcg acacaagaag catttgaagc
     1801 ctatttaaaa gaaaaaggtg ttcaattagg aaaacagcca ggtacgatcc ttcaagtcga
     1861 aacagagaaa aaaagtgcgg ctagcccacg tcttttttct ttatcgagcc ttcagtctaa
     1921 aatgaatcaa ctcatgaaag ctagtgccaa agatactttg gaagccatgc aagggttgta
     1981 tgaaggaaaa tatctaagct atccgcgaac ggatacccct tatattacgg aaggggaata
     2041 tgcgtatctg ttggatcact tagacgaata caagcatttt ttaaaagccg aagcgattcc
     2101 gactcctatt catacaccga atagtcggta tgtgaataat aagaaagtcc aggaacatta
     2161 cgcgatcatt cctacaaaaa cggttatgac agcagcggct tttgaacaac taagtccact
     2221 gcagcaggct atttatgaac aagtgttaaa aacaacggtg gccatgtttg cggaaaagta
     2281 tacctatgaa gaaacaacga tcttgacgca agttcagcag cttcagttaa aggcaatcga
     2341 aaaggtgccg ctagatctag gttggaagaa gttatttgga aaagagagcg acggaaaaga
     2401 gaaggaagaa gagccgctac ttcctaaagt gacaaaagga gaaatggtga cggtggatct
     2461 acaagttctt gaaaaagaaa ccaagccacc acaaccttat accgaaggta cgttgatcac
     2521 tgcaatgaaa acagctggga aaaccgtgga tagtgaagaa gcgcaatcca tattgaaaga
     2581 agtggaagga atcggtacag aagcgacacg ggcgaatatt attgaaacct tgaaacaaaa
     2641 ggaatatatc aaggtagaga aaaataagct cgtggtgacg aataaaggga ttttgctttg
     2701 ccaagccgtg gaaaaagagc cgctgcttac gagcgccgaa atgaccgcca aatgggaaag
     2761 ctacttgtta aagatcggtg aacgaaaagg aacacaaacc acttttctag ccaatatcca
     2821 aaaatttgtc tctcacttat tggaagtcgt accagggcaa atccaatcca ctgattttgg
     2881 atcgacgtta caagaagtga aagcagccag tgaaaagcaa gaagccgcgc gtcatttagg
     2941 aatttgtcca aaatgccagg aacaagaagt cttactctat caaaaggtgg cagcttgtac
     3001 gtctgaagcc tgtgatttta aaaggtcaga agggttcatt tgaagcaacg attgttttaa
     3061 aagaagactt cactacaggc tttgaatttt ctgaaaagaa aaaaacgaac ttcaagaaaa
     3121 gaacacgccg cactgcaaaa taatggaggg ttaatcttat gcgtaatacc acacacaaac
     3181 aacaagaaat cgaaaatcaa aaagccaaaa ttcgttcaga acaggaaaaa atgcgtgcca
     3241 gcaaacgaag actgcagcaa ttgaagaacc agcagaggat tcaaaaagaa atcgaattag
     3301 atcgataaaa tcttcctaac tattgtatac gtataaactt atgttatact gtttttataa
     3361 gtttatacgt atacaaagga gggagaaaat gacaaaagca atggtataca agctgctaga
     3421 agaatttaat ggaactttgg ctttgaagga tgccaaaaaa gcgggcattt ctcctgtaac
     3481 gatcaaacgt atggtagatc gaggggagct ggatcgagag tatccaggtt ttttcacctt
     3541 acctggtcaa tttcctgatg aattgtttat ggcgcaaaaa aaatatgaac gcggcattat
     3601 ttcacatatt accgcgttag atttgtatga tttaacagat atgatcccta gacagatcga
     3661 tctgactgta ccttacggtt atcacgtttc tgaaaaagga ttgaaggaat tcgcagttga
     3721 gctacactat acaaaagcgg aatggtatga attaggtaag attgaaataa aaagtcgcta
     3781 tgggaatcct attatagctt atgatccaga aagaacttta tgtgacattt ggaatccctg
     3841 gtataccgtt gaggatgaaa tcaaagtaaa agcaatcaaa aactatatgg agtcggacag
     3901 aaaaaatctt agaaaattga atgagtatcg acgaatttta ccaacagaca aaacgatgcg
     3961 ttcttatatt atggctttaa attaaaggag aagatacatg acacctacgc agttaaaagc
     4021 aaaagtgaag aatatttcta gagaaaaaga agttgatccg cagcttgttt taagacattt
     4081 tatgatggaa aaattcttgg aaaaaatctc agagtctcct tatcgtgaaa attttgtgtt
     4141 aaaaggcggc ttcttgattg gctcaaagta tggcattgaa aatcgcacaa ccaaagatat
     4201 tgatacgact ttacgggaaa tgaaagtaac caaagaaaca ttaacaacgg ttctaaacga
     4261 aattttttca acgccgacga aagaaggcat tcaatttgag attcaaggaa tgaaagaaac
     4321 gagagaagcc gattactatc caggatttag cttacgtgtg ctggcacatt tggaaaacat
     4381 gcggccagat tttaaggtag atgtgactac aggtgactcg atctatcctg caacgatcac
     4441 tcacagtcat aaattgatgt ttgaggatcg aacgattcct ttggaatcct atcctacaga
     4501 acaaattatt gctgaaaaat taagtgcaac ctttgatttt ttaacagata attcgagagg
     4561 aaaagatttt tatgatctct atactattcc taaaatggag aagatcgatg agaagacctt
     4621 gaaagatagt gtgagaaata catttacacg tcgaggaaaa actgatccgt taaagatata
     4681 ctatgaaaag gatatggatg tactgaaaaa tagtcacgag ctaaaagata cctggaagaa
     4741 atatcaaaaa agcaatcctt atgctgcgtc gatcacgtac gatgagacaa tggattcgat
     4801 tagtaatttg atggaaaaag tgattcacgt cgaagaaaaa gagcgaaaac tagcttatca
     4861 aagacaccaa cagatgaata gagaaatgga gagataaaga tgattaataa tgtgacatta
     4921 gtaggacgct taaccaaaga tcctgattta cgttataccg caagtggtac tgcagtagcg
     4981 acttttaccc tagccgtcaa ccgaaatttc acgaatcaaa acggcaattg agaagccgat
     5041 tttattaact gcgtgatttg gcgcaaacca gcagaaacaa tggcgacatt agctaaaaaa
     5101 ggtagcttga ttggtgtagt tgggcggatt caaacgcgga cttacgacaa ccagcaagga
     5161 caacgtgtat atgtgactga agttgtagca gataactttc aactattaga aagtaaagca
     5221 gcgacagaga gccgtgcgca cgctgatcaa tcgtccacca gtccaagcac cgccaccttt
     5281 gaacaacgga atacagcgac gcctaacaac aatggattga acgcttcaca gaatccattt
     5341 ggtggacaat caatcgatat tagcgatgat gatctaccgt tttagtttga gaaagaagga
     5401 gtaagcatgg caaaaaaaat tagtctgacg atggatctat tgatacccgt aattgcattt
     5461 atagacggga tttctttggg cgtcactgaa aatcctttgg taaatagaat tgcgaaagga
     5521 tcactatttc ttgtattcgt gtatcttgtc tgttcttatc ttttaaaaag agcaggaaag
     5581 gataattcct tttggcgatt gactaaagtc acagtagcag cgacagctgt tatacttacg
     5641 gctattctac cgctttatat gtagagttaa cgggaaatcg ttgaacttct tgcgaaatat
     5701 tgctataatg aacatgaaaa agaggagttg cgctaacaac ccctcattaa cagcaccgat
     5761 taaagaacgg tggcagaata ttagttattt ggaaataacc gctgacctgc taaagtagac
     5821 ggttatttct ttttgtcatt tttaagcata tttacaatca aactaatcaa agcaatggta
     5881 aacataccaa aaccaagaat ggtttgaatt gtctcatatg cggacaaaag gcttactcct
     5941 ttcatagatt ttagcactta cattcataag caccaccacc tttccagaag tcgccaccgt
     6001 cttcaaactt tactgtcttg actattatag catatctaaa atcgaataaa aattctcaat
     6061 tttagctgtt tttgctataa ttttagcgag gtgatcgtga tggaacaata tattggttta
     6121 ctcgataaat tagggtgatc aagacacagc cattgcttgt gcgatttaca ttacgcacga
     6181 gtcatgaacc aatcaattgt gtagtggcca atatagaaat agcggataaa ttgctgattt
     6241 tggaagaagg caagtatact atttcagtga caggtcactt caataaacga aagcaactag
     6301 tcattgaatc aatgcaaatt agaaaccctg atcattttac gcgatcgatg agcatataaa
     6361 agaagagctg cagtcctaaa tgaggattgt agctcttttt gttttacata gaaacagtaa
     6421 aaatgaaaag gcctgtttag gaaggcacaa gcgccttctc aattgaaaga cctttctctc
     6481 actccaaccg ccaccgccgt tcgagaagaa aggaagtgaa cgctacgcgt tcactaagat
     6541 aaagtgtctt gcatagcaag acaaaataga aaaaatttcc tctcaccaaa aggttcgctc
     6601 ctgttcgtta tctctttatt gatttgtcag accggcaaca agttgccttt tatcaccaaa
     6661 aagcgacaag gacaagggta aatggcacgc tgcgcgccct tgtcttgtcg cttttcgttg
     6721 attcattctg gccaacaaat caataaagaa agaactaacg aaaggaagta aaacctttcc
     6781 taagaggagg cagaatcaat catgcgaaag aaatttgatt attggggtgt tcccttcagc
     6841 gaattattcc caaactatca tgcaccacat actgtcgaat gcgattgtgg agaaagagcg
     6901 aaatgtatca aaagctattg tttgtatcaa tgtccaacat gcgggaaaaa atataccttg
     6961 tcttatggcg attatatttt aattgatgag aaaggaaaga aacgctgatg aaaacacaac
     7021 acaaattatt gactgtaaaa gaagtcgttc aaattttggt ggacaaagaa gtcatttctg
     7081 aaaaagtagc agaagtttta cttattccgc ggtactggac gatagaaacc cctttagtag
     7141 aggatgcacc gactatgcta tttgaagacc tagtgaagat tgcaggatat gaactgcatt
     7201 atcaagaaaa cttggaaact tatgaaaacg aatattggtt aaccaaatta gagaactaaa
     7261 aaggagaaaa aatatggctc aaaattacta tgacgaattt gtcaaattac ctttggataa
     7321 aatggcacaa aaaatggagg atatgacgtt cctatacaac gaaacacgtg ttccaaaaaa
     7381 acattataaa gaaaaattgt cggtagctgt ggaagaaatg attgaataag gtgtcgaaat
     7441 gaatcttatt gcgacgtact atcgaacact ggaagaactg aaaaagcaaa atgcaaaatg
     7501 gtttttccaa gccttactat gcttggaagt aggtgtcaaa ccaagcacta ttaaaccttc
     7561 tgaataccaa gctttagaac taacgtatgc gaaatttatc gaaacgaaaa aagccaagac
     7621 tgtttcaagt gaatggttag attattttga aaatatcaat aagtatggcg catattacac
     7681 catgaaaaag gaagacaacg aaaatgaata aggtgattta tcaactaaca acggattcca
     7741 tatcaacgat ttgaaagaaa aaaaggtcaa taatcattta taccgaaaag tgagaatgtg
     7801 tgaaacaagg acaaaaaaag cctagtaact aaggaaatgg ttcttatttc gcaccaatcg
     7861 ctccaaccgc ccccgccgct taggtggtgc gaaataaacg ggcaaagccc gataacttaa
     7921 gagaaagaag gtgatccatt tgaacaagat tattccctta ttgttagtac tgtttgttgg
     7981 cgaaatactt atgcgagata gtgcagctgt acagttaaac ctcgctgtat ttttggtaat
     8041 actggtgttt tgtttgatct tttggcggtt tgtattagtc ctcgtgagtc tactattcaa
     8101 gatgattgca gccatatttt tcatagggtt atttcgatga aaggagtgag taccaatgcc
     8161 aattgcaata ggaaataaac ggttacccgt gacattagat gaaaagagac aaaaagaatt
     8221 gcagcaacta aagcagaagt atggcaaaag tgaatctaag attatgtgta ttgcgttaga
     8281 tctattgatc gcgcaagaaa aagcaggatt tgatgtacca gcgctaaaaa agtgacgtca
     8341 ctttttaatt tgatctatat aagtgatatc acttttacca aggagggaat taaatgttaa
     8401 aaactaaaaa gaattcgtac aaattaaagc ttagtatact atctattatt tgtcttttag
     8461 gcatgataat tagtggtcat ttgtatagag tggcatatac gcagtttatt gagtacaagg
     8521 ttcactcttt aggattagct ggggatcgat acgttgaata tgtccattat tcattaaaat
     8581 gttcttcata tattcttctt tggcttattt tttcattgtt tgaattgcta aatttaatag
     8641 caatatcttc atatcactta gataagctaa ataccaaatc tagccgttat aacgaagtgt
     8701 ttaaggaaaa tgtgaagtta gaaagtgact taaacaagct aaaaaaataa aaagaagaaa
     8761 acataagtta actaaaatta ttttattaag aatgatggaa tataaggata aggttaccaa
     8821 cataacgatc attacttctc tgatatgcta tggacttcta tcaatcagta ttttgtctat
     8881 agattatgga gtaactatac tgcaagcctt agttttggct atgcctatgt atctatcttt
     8941 gtttatcatg catgaaatat ataagctatt tgttttatca aaaaatgtag aaatacgggt
     9001 aaatattttg gtgaatagtt atcaaaaaga actcaaagaa agaagacggt ggcggtattt
     9061 attgaaagga tgaaaaagta ggatttgaca tactggtatt cagaaagtgc cgtcactttt
     9121 aaaacaatgg aaaaggtgga gataagatga agaaaaaaca aactaaacta tcattagcag
     9181 atatttaaca cagttaaccg caactgaaga tggtgttgtt gaatttgaac aatctgaaat
     9241 tgcggtagta gatgatcgtt accttaaaat gccttacttc tttgaccaag caaaggtcat
     9301 ttgccttttt cactacgatg gggtacgtga ttttaggcgt taaaaagtag tgattatatc
     9361 aactttacga gtaaatataa atttagacat gaaactgaat tatccaatgg aaaatcatgg
     9421 tttataatct agaaaaatta tagtaatgat tggattatat atattctttc gtattttcgt
     9481 acaactgtag cttgtcaaaa ttgagaaatt taaccgatta ggtactttac atcgttattt
     9541 gggtaatttc taaaacatga agcttaccaa cgaataaact gagactatct tattaattga
     9601 tcaatataag aaaatatctt tgaggagatg atgtactatg ttttcgtcta tccacgattg
     9661 gttaggtggt cttttcggcg gtggcggtaa aggttttta
//
LOCUS       DAPBAF010000074         9602 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.076, whole genome shotgun sequence.
ACCESSION   DAPBAF010000074 DAPBAF010000000
VERSION     DAPBAF010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9602)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9602)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9602
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.076"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(<1..613)
                     /locus_tag="RD451_002600"
     CDS             complement(<1..613)
                     /locus_tag="RD451_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element IS1476 family transposase"
                     /protein_id="HDT7567809.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGKLDDSP
                     SYCEHCRSVRIIRNGSYTTRTQILKVKEKLTILELKRTRFLCHDCGRTFSAKTDLVDE
                     HHQLTKELKQAILMELYENQSRKLIAKKYFVSDGTVTRILREATKHYQSRMNFLPTVL
                     CMDEFKSMKSVSGSMSFICVDGTTHQLFTILEDRRLYKLTQYFL"
     gene            814..2028
                     /locus_tag="RD451_002601"
                     /pseudo
     CDS             814..2028
                     /locus_tag="RD451_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(2207..2536)
                     /locus_tag="RD451_002602"
     CDS             complement(2207..2536)
                     /locus_tag="RD451_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HDT7567810.1"
                     /translation="MNTNDIATVYVAFTAAEGGKRRPVYILKNGLDTISFLSITSKYH
                     TKSDKIKLKYVEIRDWKQAGLKKESWIDVGTLNELPKNNKKVKWKKIGELSPSDLQRL
                     EERMEEL"
     gene            complement(2526..2798)
                     /locus_tag="RD451_002603"
     CDS             complement(2526..2798)
                     /locus_tag="RD451_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HDT7567811.1"
                     /translation="MEKMAKLQISMDEKLKNEAESIIDELGMSPKTAVTVFYKQIVEQ
                     GKIPFSIELSEKSKRIHNIQRLAEKLPVQKLDTDEKIEEWFNEDEY"
     gene            complement(3249..4052)
                     /locus_tag="RD451_002604"
     CDS             complement(3249..4052)
                     /locus_tag="RD451_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDT7567812.1"
                     /translation="MRFLHLSDIHFRENYQTNLFTAELFPTIKNPQLALEKLLQELSL
                     TVYDFILLTGDLVHEGGISDYQVLRKMLDQYFPTTPYYFCRGNHDRRSVFFEGMSVES
                     NETGEYIHCTNQNGLRIISLDSAQDTQHEGKISIGQMIQLQEWLGTPAEKGTILLVHH
                     PLSWEDPSIVTEVPEGFAELIAESDILGIFVGHIHQGSSAEFAGKKQFMAESLSFGVD
                     EYPDYSLFTNRTGFTSGSLIDGKIFTYQHYLTPHQIEIGRMKKPITGNH"
     gene            complement(4030..5154)
                     /locus_tag="RD451_002605"
     CDS             complement(4030..5154)
                     /locus_tag="RD451_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7567813.1"
                     /translation="MGETLELRNIGKKYGEHTILKEIDLAVAAGERIVLLGPSGSGKS
                     TLLRMIAGLEKITSGELFLGTQLANKLPCGEREIAMVFQNYALYPHMTVKENIIFALR
                     ANKIKTADIQHRLEEALKMLGLTPYQDRLPKDLSGGQRQRVALARAVVKRSNYFLLDE
                     PLSNLDVRLRLDARKELVKIHQRYKQTFVYVTHDQIEAMTLADRIVLLNEGRIQMIDT
                     PKNVYTKPKNTFTANFIGSPGMNIMPVTYDQGTLKVASQFLTLNPAWQKQLLQVSGSL
                     YLGIRPEHVTFSKETSDLHGQVKYRELLGQSYAYTVKVDGIEMIVLNEKPTWQIGDAV
                     NLRIEPERMHFFDYQTQENLGYPDYFIEERGNSHALFASL"
     gene            complement(5170..5985)
                     /locus_tag="RD451_002606"
     CDS             complement(5170..5985)
                     /locus_tag="RD451_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDT7567814.1"
                     /translation="MKIKRWLPHLLFMFIIIIIIYPLLFIMANSFKPLKDAYQTITSL
                     IPQPFTLENFCYLFENLPIIKITRNTFFIATIITVVKLGVAFFAAYSFTYCRIKGKKI
                     WYFIIIGTMFIPFTVAMIPNYLLIAKLNLIDTTWGVIIPQFADAMGIFLLTQTMREIP
                     VSLLDVAALDNIKQTTVMSKIVFPLTRHAITSTGIWFFITSWNEYVWPVLILRTVDNY
                     TLPLAMQTYISSEGGTNFTVAMAISLITMFVPLVLYAIFQKYIIGTFVSAGIK"
     gene            complement(5975..6847)
                     /locus_tag="RD451_002607"
     CDS             complement(5975..6847)
                     /locus_tag="RD451_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDT7567815.1"
                     /translation="MKRYVGYLYLAPAIILLGVFVFYPLIYTIYLSFFDWNMVAPTKE
                     FVGFANYVKVLTDPVFHKVLKNTLSYTVLFVLLSCVFPYITSFLLGIVIEKGQNLYKP
                     LFFIPAVISLVVAGMVFTWILNPVSGPIAVLLGNFGLRLPMWMNLQGWVIAVIAGITA
                     WKVFGYNFIVIFAAIVGIDQEMIEAAKLDRVPIWRIFFTIVLPMSSSTGLYLLVMTIV
                     QGLQYVFTPIKIITRGGPNNGSANVIYYAYQKAFEMYKVGESSAISVLTLLIFAVFLG
                     VIFKFVEKGVYYEN"
     gene            complement(6932..8221)
                     /locus_tag="RD451_002608"
     CDS             complement(6932..8221)
                     /locus_tag="RD451_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDT7567816.1"
                     /translation="MLKKNLVIGVVSVLSVISLAACGSGNTKTTKKSEGRVTIEYWHV
                     NADTLGGKTVNELVDKYNQSQDKVKVVAKYNPDMYKGLMQNLQASVASKEIPDVVQVG
                     WAFKDYFAENFKYTNPQSLVEEVDPDNADYFKDHFLDNIMALSEKDGKQVGIPYSISN
                     PVLYLNQDILKAAGLDENGPKTWEEVQTFSKIIKEKTGKYGVYIQEPADNWAQQAILE
                     SNGASVIKDGKATFASKDGIAAYELYQRMVKDQTALHTTWEQGVQSFIDGNVAMVYTT
                     IAQRDNIQKNSTFTAKAVESPSWEGKKVKLPAGGAMLAVTSQTDKKKEATWDFLKYLY
                     SVESLAKWTEGTGYLPPRKDVADAQNGLKAFLAENQMMIPAIDQMDKMVSWSSFPGDA
                     GLEAEQKLLDMRDKILSGNSVNETMKATQKEINELLK"
     gene            complement(8449..9093)
                     /locus_tag="RD451_002609"
                     /pseudo
     CDS             complement(8449..9093)
                     /locus_tag="RD451_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
BASE COUNT         2966 a         2027 c         1554 g         3055 t
ORIGIN      
        1 gcaggaagta ttgagttagt ttgtaaagtc tgcgatcttc aaggatcgta aatagctgat
       61 gggttgtccc atcaacacaa ataaaactca tggaaccaga aacagacttc attgatttga
      121 actcatccat acacaacacc gtcggaagga agttcatacg tgactggtaa tgcttcgttg
      181 cttcacgcaa gatccgtgtc accgtcccat ccgagacgaa gtacttctta gcgattagtt
      241 tacgtgattg attttcgtac agttccatga gaattgcctg cttcagttcc tttgttagtt
      301 gatgatgttc atcaactaag tccgttttcg cagaaaaggt ccttccacaa tcatggcaga
      361 gaaaacgggt acgttttaat tctaaaatag ttaacttttc tttgactttc aatatctgag
      421 tgcgtgtcgt ataggaaccg ttgcggataa tacgaaccga tcgacagtgt tcacaatagg
      481 aaggagagtc atccaatttt cctttaataa actgcgcttg aacgccttta tattcttttt
      541 caatcagcca ttcttcatca aaaaataaat gtttatctgt taatccgagt aattttctag
      601 tatgattatc cattgagaga ctcctttggt aggatgacgt tttggtcgac taaattttac
      661 caaaagtgag tctctttttg agttgaaacg aagaaaaagt gttagtagaa aatcgccttc
      721 gattttccac caacacaaaa tattatagaa gcaaaatcaa ttctacctta gatgttctta
      781 tatcactcta tcagtcctat ttgacaaaga gccaagaaaa agacgttggt cgtcgatgct
      841 gttctctcgc ctactcctcg tgcttgtaga agttgtggtt ctactgtggt agatggaaac
      901 gggaaagcaa ttatagtgaa aaatgggaag aaggaaacga ttgtccgttt tgaacaatac
      961 aatcatatgc ctttggttac gcgcctaaaa aagcaacgct atacctgtaa aaactgtcgt
     1021 acccattgga cggctcaaag tttttttgtc cgactcagcc attcaatcgc agatcatgtt
     1081 cgatataaaa ttgcttcttt actgactgaa aaagtatctt tgtcttttat tgcgaaaagt
     1141 tgtcaggtat ctttgactac cgttactcgt acattgaaag agtttaaaag ctatttacca
     1201 aagccttcta agaagattct ccccagagta ttgatggttg atgaatttcg ttcgcacgct
     1261 tccatagaag ataaaatgag ctttatttgc gcagatggtg aaacaggaaa cttaattgct
     1321 gtcttgccta cgcgtaaatt acctcgatta acaagctatt tcttaggctg caccaatcca
     1381 gaagaagtag aattcttagt cacagacatg aacgccgctt acttccagct taccaaacgt
     1441 gttctgccaa atgcgaaagt agtgattgat cggtttcata ttgtcaaaca catgaatcag
     1501 gcactcaatg agttgcgtat ccgtgaaatg aatgagcttc gtaaagcagg acagaaaagt
     1561 caggcagaaa aactgaaaaa gaactggcgc tttctgctaa aaaatcgtgc aagcatcaac
     1621 cattatgagt acaaaacatg gaaaagtttc cgagcaccaa aatacccatt tctcactgaa
     1681 gcaatgatga ttgatcgatt gcttgagttt tctgcgcctc taaaggaggc gtatcccttt
     1741 tttcatgaat tagtcgaagc ctttcgagac aaagaccctg acttattttt ctccttattg
     1801 gcagaacttc ccgaaacgtt agatgacggc tttcgggaga agcttcaaaa ccttctgacc
     1861 tatgaagaag gtatcaccag cgcaatgatc tatccttatt ccaatggaaa aattgaagcg
     1921 aagaataccc acataaagac aatgaaacga gtatcctacg gatttaaatc attcgagaac
     1981 atgagaatta gaatcttttt gatcaatcaa ttaatcaatg taagataaca aaaaatctga
     2041 accagaatgt ggttcattct gacccggatt tgattttgca caactcatca gtccttattg
     2101 acaaagagcc aaaaatctga gccagaatga ggttcattct gacccagatt tgattttgta
     2161 caacccatca gtccttattg acaaagagcc cttcttttta gtattattat aattcttcca
     2221 tgcgttcttc cagtcgctgt aaatcgcttg gacttaattc cccaattttt ttccatttga
     2281 cctttttgtt gtttttgggt aattcgttta gagttcctac gtcaatccaa gattcttttt
     2341 ttagtcctgc ctgtttccaa tcccttattt caacgtattt cagctttatt ttatcggatt
     2401 tagtatgata ttttgaagta attgacagaa acgaaattgt gtccagtcca ttttttagaa
     2461 tatagacagg ccggcgttta ccgccctctg cagctgtgaa agcaacgtag acggttgcta
     2521 tatcattagt attcatcttc attgaaccat tcttcaattt tttcgtcagt gtctagtttt
     2581 tggacaggca atttttccgc taatctttga atattatgga ttcgtttact tttttccgac
     2641 aattcaatag aaaatgggat ttttccttgc tcaacaattt gcttataaaa aacggtgacg
     2701 gctgttttgg ggctcatgcc tagttcatca ataatgcttt ctgcttcatt tttcaatttt
     2761 tcgtccatag aaatttgtaa cttagccatt ttctccacct ctttctgaca aacacattat
     2821 atcacggaaa gagttcaaat ggaattaata caactacttt tgaactcctt gaaatgcagt
     2881 gtatttatct aaatataagg aaaggatata gtgctaaatg gccttgatag atagaaaagt
     2941 ttcaaaatcc gccacagcga taattgaagc gaacactcaa cgacacacag aacaggaaaa
     3001 gactcctaaa agaaccaaat taactaggac gtgtctgaaa actccacaaa gatgtggtat
     3061 gctctggtaa aaaacgaatg gcacaaccac gaagaccgat atggttcttg gaaaactttc
     3121 tccacccttt ttgtaattgg agggatagtg gtttattgat agcgattttc caagttcttc
     3181 aagtggaacc agacattgag caccacggct aaaaagtgaa tgaagtcttt atttttaatc
     3241 aataattttt aatgattacc agtaattggt tttttcatgc gccctatttc tatttgatgt
     3301 ggagttaaat aatgctgata agtaaaaatt tttccgtcaa ttaaactgcc actagtgaat
     3361 cctgttctat tggtaaaaag agaatagtct gggtattcat ctacaccaaa tgataaagat
     3421 tcagccataa actgtttttt accagcaaat tcagcactgc taccttgatg gatatgtcct
     3481 acaaaaatac ctaaaatatc actttcggca atcaattcag caaaaccttc cggaacttca
     3541 gttacaatag atggatcttc ccacgacaat ggatgatgaa ccaataaaat cgttcccttt
     3601 tcagcaggtg tacccaacca ctcttgtaat tgaatcatct gtcctatcga tatttttcct
     3661 tcgtgctggg tatcttgagc agaatccaag gaaataattc gtaacccatt ttgattcgta
     3721 caatggatat actctcccgt ttcattgctt tcaacactca ttccttcaaa gaaaacactg
     3781 cgacgatcat gattcccacg acaaaaatag taaggtgtgg ttgggaaata ttgatccaac
     3841 attttccgta agacttgata atcagaaatc cccccttcat gtactaaatc acctgttaat
     3901 agaataaaat cgtacactgt taacgagagt tcttgtaaca atttttccaa tgccaactgt
     3961 ggatttttaa ttgttggaaa tagttcagca gtaaacaagt tagtttgata gttttctcta
     4021 aaatggatat cagagagatg caaaaagcgc atggctattc cctctttctt caataaaata
     4081 atcaggatat cctaaatttt cttgcgtctg ataatcaaaa aaatgcattc tttcaggttc
     4141 tatgcggaga ttgactgcat caccaatctg ccaagtaggt ttttcattaa ggacaatcat
     4201 ttctatacca tcgactttaa cggtgtacgc ataactttga cctaatagct cacgatactt
     4261 cacttgaccg tgtaaatcgc ttgtttcttt tgaaaaggtt acgtgttctg gtcttatgcc
     4321 taaatacaat gagccactaa cctgaagaag ttgtttttgc caagctggat tcaatgttaa
     4381 aaattgactg gctaccttta atgttccttg atcataagta actggcataa tattcatgcc
     4441 tggcgaacca ataaaatttg cagtaaaagt atttttaggt ttcgtataaa catttttcgg
     4501 cgtatcaatc atctgaattc taccttcatt caataaaaca atccggtcag ctaacgtcat
     4561 cgcttcaatt tgatcatgag tgacgtagac aaaagtttgt ttataacgtt gatgaatttt
     4621 taccaattct tttcgtgcat ccaatcgtaa acgcacatcc aaatttgata acggttcatc
     4681 taataaaaaa taattactcc gtttaaccac cgcacgagcc aatgctacac gctgccgttg
     4741 ccctcctgac aaatctttag gaagtcgatc ttggtatggc gttaaaccta acatcttcaa
     4801 agcttcttcc aaacggtgct gaatgtcagc tgtcttaatt ttattcgccc ttaatgcaaa
     4861 aataatattc tcctttacag tcatgtgagg atataaagca taattttgaa aaaccattgc
     4921 gatctctcgt tctccacaag gtagcttatt tgctagttgt gtacctaaaa aaagctctcc
     4981 actcgtaatt ttttccaaac cagcaatcat tctcagcaaa gtagattttc ctgaaccaga
     5041 tggtcccagt aacacaattc gttctccagc ggccacagct aaatcaattt cttttaaaat
     5101 ggtatgttct ccatattttt ttccgatatt tcttaattca agcgtttctc ccatgatttg
     5161 tcctccaatt tatttaatac ctgcagaaac aaaagtcccg ataatatatt tttgaaaaat
     5221 tgcatacaag actaacggta caaacattgt aattaaacta atcgccattg ctacggtaaa
     5281 atttgtccca ccttcagaac taatataggt ctgcatcgcc aacggcaaag tataattatc
     5341 tactgtccgt aaaattaata ccggccaaac atactcattc caagaggtaa taaaaaacca
     5401 aataccggta gaagtaatcg catgtctagt aagaggaaaa acaattttac tcatgacggt
     5461 tgtttgtttg atgttatcca atgccgccac atctagaagg ctcactggaa tttcccgcat
     5521 tgtttgcgtc aataaaaaaa tgcccatcgc atcagcaaat tgtggtatta tcacacccca
     5581 agtagtatca attaaattaa gttttgcaat caacaaataa ttaggaatca tcgcaacagt
     5641 aaaaggaatg aacatcgtac caatgatgat aaagtaccag attttcttcc ctttgattcg
     5701 gcaataagta aaactatatg ccgcaaaaaa agctacgcct aacttaacaa ccgttataat
     5761 tgtagcaata aaaaaagtat ttctcgtaat tttgataatt ggaagatttt cgaacaaata
     5821 gcaaaaattt tccaaggtaa acggctgtgg tatcaaacta gtaatcgtct gataggcatc
     5881 tttcaatggc ttaaaagaat tggccataat aaacaataat ggatagataa taatgattat
     5941 gatgaacata aataagagat gtggcaacca gcgtttaatt ttcatagtaa accccctttt
     6001 ccacaaattt aaatattacc cctaagaaaa cagcaaatat taataaagtt aaaactgaaa
     6061 ttgctgaaga ttctccgact ttatacattt caaaagcctt ttgataagca taatagatca
     6121 cgtttgcact accattattc ggtccaccac gagtgatgat cttaatcgga gtaaacacat
     6181 actgcagacc ttgaacaatg gtcatcacca ataaatatag tcctgtcgaa ctactcatag
     6241 gcaacacaat tgtaaaaaaa atgcgccaga tgggtacacg atccaactta gctgcttcga
     6301 tcatctcttg atcaattccc acaattgctg caaaaatgac aatgaaatta taaccaaaaa
     6361 ctttccaagc agtaatacct gcaatcacag caattaccca accttgtaaa ttcatccaca
     6421 taggcagtct taaaccaaaa tttcccaaca agacagcaat tggtcccgat accggattta
     6481 atatccatgt aaaaaccatc cccgccacta ccaaagaaat cacagctgga ataaaaaata
     6541 atggtttata caaattctgc cctttttcta taactattcc taataaaaag gatgtaatat
     6601 atgggaacac acagctcagc aagacaaata gaacggtata ggacaaagta ttcttcaaca
     6661 ctttatgaaa gactggatca gtcagcacct ttacatagtt ggcaaagcca acaaattctt
     6721 tagtgggggc caccatattc cagtcaaaaa aactcaaata gatcgtataa atcaatggat
     6781 aaaaaacaaa cacgcccaac aaaataattg ctggcgccag atacaaataa cctacatagc
     6841 gcttcatttc cgacagcctc ctcatcctta tgtcaaaagc agacgacctt gtttttcctt
     6901 tcttacaggc gctgtcgtct gcttgctttg cttatttgag taactcatta atttcctttt
     6961 gagtagcttt catcgtttca ttgacggaat tacctgataa aattttatcc cgcatatcca
     7021 acaatttttg ttcagcttct aatccagcat ctccaggaaa tgaactccaa ctgaccatct
     7081 tatccatctg atcaattgct ggtatcatca tctgattttc agctaagaaa gcttttaatc
     7141 cattttgggc gtctgcaaca tctttacgtg gtggtaaata accagtacct tctgtccatt
     7201 tagctaaaga ttcaacacta taaagatatt ttaagaaatc ccaagttgct tcctttttct
     7261 tatccgtttg tgatgtaaca gctaacattg cgccaccagc aggtagttta acttttttcc
     7321 cttcccaact tggtgactca actgctttag cagtaaaagt actatttttt tgaatgttgt
     7381 ccctttgagc aatagtggta tagaccatcg cgacgttacc atcaataaag ctttgcacac
     7441 cttgttccca cgtagtgtgt aatgccgtct ggtcttttac catcctttga tataattcat
     7501 aagcagcgat accatcttta gaagcaaagg tagctttgcc atcttttatt acacttgccc
     7561 cattactttc taaaattgct tgttgtgccc aattatcagc aggttcttga atatacacgc
     7621 catactttcc agttttttct tttattatct tagaaaaagt ttgaacttct tcccaagttt
     7681 ttggaccatt ttcatccaag cccgctgctt ttaatatatc ttgatttaaa tataaaaccg
     7741 gattactaat ggagtaagga atacccactt gtttaccatc tttttcagac agtgccatga
     7801 tattgtctaa aaaatgatct ttaaaataat cagcattatc cggatccact tcttctacta
     7861 aagattgagg attagtatat ttgaaatttt ctgcaaaata atctttaaaa gcccatccca
     7921 cttgtactac gtccggtatt tctttggagg caacagaagc ttgtaaattt tgcatcaagc
     7981 ctttatacat atcaggatta tattttgcta caaccttcac tttgtcttga gattgattgt
     8041 atttatctac taattcattc actgtttttc cacctagggt atccgcatta acatgccaat
     8101 actctatcgt tacacgaccc tccgattttt ttgttgtctt ggtattccca ctaccacaag
     8161 ctgccaaaga gatgacactt aaaacagaca caacccctat aacaagattt ttctttaaca
     8221 taacattaac ttcctcctaa tttctttatg gccatttttc taatcaagaa atattatgaa
     8281 ctaccaatgt aaatttctag ttaattttct gtaaataatt cgaaatttgt gcatttcggg
     8341 gtacagggtc actggacata tccatcaagc taagaataaa gcccccatat ggtcatgtat
     8401 cccatctcca aatctcttaa ctcctctgtt ttgattataa aatagtttat tctgtgctcc
     8461 tttcttccat aaataggccc atgcacaacg tgaggttata ttataaacac cacagcgcgc
     8521 aaggtactca atcgtttcta gttcattgac tgtccataca gaaaatgtca atcctagctg
     8581 ctgccccact tcacgggcca acttagttaa ccatccttca tgaatattga cgatttgaac
     8641 gctttgatag gctaatttct gtaaggtatc gatcaaatct gcttcggtaa tatccccaag
     8701 ttttttccct tcgaactgat tttcaatatt ataaaatata tgctttcccc aaatcgcagc
     8761 ccaagataat tgtacatagc cactaagaac aatttgtggc cagatttgat aggtttgtgc
     8821 cagcgaaaaa acggccattt ccaatccctc ttcttttaaa tcacagttaa tggtcatggt
     8881 tgccttctca ttggccactg cttgaaacac ctgctcaagg gttaccgaat ctgggacaac
     8941 ttcttacctg tcatgggcta gtattagcgt accatctgtt tgctgacgca catctacttc
     9001 aaaacaaagc tggcgatcca aacaaaagcg aagaaatgcc cagctattct cctccgtatt
     9061 gtcactacca gagtgtgcag tgatcatggt cattttgacc cctcctttaa ttccgtgatt
     9121 ttctcccaca cgtccactat accgatgaag cgttaatttc ttgttaattt cttgtaaatt
     9181 ccctgcgttt tttcagtaaa ctagttgtaa atcttgcatg ctccttccta cgaactcatg
     9241 aatcgtcgat tttgcccttc tagctagttt caccaattaa gtagttctac attccccgct
     9301 tttaacctac tacacctttt tttgttttca gctattcctt cttcttgctg aaagtccttg
     9361 aggttctttc ttacaggata ccatcaaggt gttcaatggc ttattcccat tgaatgaccg
     9421 agacttacta tcagatttct gctcgttgaa ccaagtcttt gatacaggat ttcttccgtc
     9481 atcttctcac aaataccacc ttgcgtttct ctagcgattg gtcgatgtgc accctcccag
     9541 tggactgtca ctaccccttt ttgctatgcc tagcccacaa aaaaagctgt cctcacagac
     9601 ag
//
LOCUS       DAPBAF010000075         9595 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.077, whole genome shotgun sequence.
ACCESSION   DAPBAF010000075 DAPBAF010000000
VERSION     DAPBAF010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9595)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9595)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9595
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.077"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(<1..643)
                     /locus_tag="RD451_002610"
     CDS             complement(<1..643)
                     /locus_tag="RD451_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HDT7567817.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFIFFFVLLELFFAVFLFLGKNSLKQTK"
     gene            complement(645..1409)
                     /locus_tag="RD451_002611"
     CDS             complement(645..1409)
                     /locus_tag="RD451_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HDT7567818.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            complement(1417..2094)
                     /locus_tag="RD451_002612"
     CDS             complement(1417..2094)
                     /locus_tag="RD451_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HDT7567819.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            complement(2131..3516)
                     /locus_tag="RD451_002613"
     CDS             complement(2131..3516)
                     /locus_tag="RD451_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDT7567820.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            complement(3726..3810)
                     /gene="ffs"
                     /locus_tag="RD451_002614"
     ncRNA           complement(3726..3810)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="RD451_002614"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(3833..4348)
                     /gene="tadA"
                     /locus_tag="RD451_002615"
     CDS             complement(3833..4348)
                     /gene="tadA"
                     /locus_tag="RD451_002615"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HDT7567821.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            4455..5312
                     /locus_tag="RD451_002616"
     CDS             4455..5312
                     /locus_tag="RD451_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7567822.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYRYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            complement(5393..5728)
                     /locus_tag="RD451_002617"
     CDS             complement(5393..5728)
                     /locus_tag="RD451_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567823.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(5795..7165)
                     /locus_tag="RD451_002618"
     CDS             complement(5795..7165)
                     /locus_tag="RD451_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HDT7567824.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            complement(7243..7779)
                     /locus_tag="RD451_002619"
     CDS             complement(7243..7779)
                     /locus_tag="RD451_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDT7567825.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            8088..9569
                     /locus_tag="RD451_002620"
     CDS             8088..9569
                     /locus_tag="RD451_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7567826.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLKKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
BASE COUNT         2909 a         1969 c         1502 g         3215 t
ORIGIN      
        1 tttttgtttg tttcaagcta ttttttccta agaaaagaaa aacagcaaaa aataattcta
       61 ataatacaaa aaaaaagata aagctatgca tgaaaaattc ttctggaagt acattgatga
      121 ttggatcagt aacgggatcg aataaccagt catcgttgtt gaaaaacgtt tcatgaaaaa
      181 ggataaaaaa gcgatcaaat cctatcatca tgaaaaaacc gaaaacaact ggcagtaaca
      241 tgccgatttg aaacggacga atcaaccgcc aaagccgatc attcttttgc aaatatttga
      301 taaacaaaat actcgggatc aaagtgatga aaaacacagc ataatccact aaaaacaaaa
      361 ttttcacttc ataaaagtga tgggctccgc tagcagaaac tgggaaatct ggcaagctga
      421 ggatggtttt gaagggatta ttgagataat tcattaggtg atcaaaattt ttcagtaacg
      481 tctcttgatc taaagaagta taatccaaaa tttgcaaatg tccgatatca aatacgtata
      541 gtggtcgaaa gttgatcgtc acaccaactg ccagactgat cagtgtcaga aataggctga
      601 acaatccagc atattccatc cactgccatc tcgaattttt catattagaa gctccattca
      661 tccagtgatt gtttcacata ggtagctggg ataggcaacc caggtacatc ttcttctttt
      721 gtaaaacctg ataaaacgag caaagtatct atattattgc gtatcccagc ttggatatct
      781 gtttcatagt tatctccaac catgattact tcttcttttt gcagccctaa tacttcaacg
      841 gctttatcca taatgatggc ttctggtttt ccgatgtaga tcggcggcgt ttgggttgct
      901 gtctctacaa aagagatgac tgaccctgct ccaggaagaa ggccgcgttc agtaggtata
      961 ttcttatctg ggttcgttcc aatgaaagta gcaccttttt gaatagcaag tgttgcttta
     1021 actacttttt cataggtcag ataattatct aagcctacca ctacatagtc aggagcctct
     1081 tcttcccatg taaatccggc agctaaaatc aagtcaatca atcctgcttc tccgataaca
     1141 tagacttttt tcccttttcc atctgctttc ataaaatcga ttgttgccaa agtagctgtg
     1201 tagactgtct ctggagctac atgaatgtca aactcatctg ctagacgatt agctactgtt
     1261 tctggtgact tagtcgtgtt attggtaaca aacaagaaag gtaattttct tttttgcaat
     1321 tcttccacaa atcgtttacc ggccggtatg ggttgtgtcc cacgataaat cgttccgtct
     1381 aaatcaatta aatatccttt atagtccatt catccactac tcttcccttt ttctgatcgt
     1441 aaatgctgtt tttgtttttt ctacttgttt aggttgttct tgttttttta ctttttcaga
     1501 ggtttttgct gactctgttt ttcgattttt aataaccggt tttttgcgat tagatgcgac
     1561 tggtcctttt ttctcatcga tatacgcacg attatggttt tttttctttt ttcggcgctg
     1621 agttgtcttt tcttttttac cgccgattct ctcgatgaca aaatacgcac aaccaaaatt
     1681 gcaatattcg taaagatagt cttccaagga atcgattcgc tgatctggat gcgcccgtcg
     1741 attatccgct tggaaaaatc cttttaggcg tagttgttca taaccccaat ctcctacgat
     1801 ataatcatat cgggctagta catcactgta acgttctcca agcttttctg cattaaatcc
     1861 ttcacgataa tcggacacaa gccgataatg tctttcacct atcaaaaaat tactgtcatc
     1921 taacagtgtc actagctcgc ctttgacttt ttctgcttta ggctcctcaa cgatttcttc
     1981 caaagcagct gtcagttctt cggtgactgt tgtttcctgt tcagctgatg attttttctt
     2041 agcaatttct gttttatgct caacgttctg ctgttcattt tgttttgcag acatgcgttc
     2101 accacctatc ttttttatta taccttgttt ttatttgatt gggtagtgag ctttcaagta
     2161 atctcctacc acacttcgga taaattcagg gaacaaaaat tcattttttc cagcaatctc
     2221 aatcgttgga aaaaatggaa caaacatcaa atgatctacg gtagtaaaag tataattttt
     2281 attcagatcg attggcttgt tcttccaaaa gacttgatgg ttaatagaat catatgtgat
     2341 tccattatag accatctgcc caaaaatctt accgcgaaat cccattccct tcataggata
     2401 gttacgtaaa aagttacgat ttttttctat ttctaaaact aagcggatca gatcatttcc
     2461 acccaatgtg acatttaaca agtgcatcgg atgcggcaac gcagtgtgaa gctgatcctg
     2521 attgacccgc ccttttggaa tttcagttaa aaacagacca ctgtttaata ttgctgcttc
     2581 cgtctttcct cgttctttca ccgcctcaaa ggctacttgg ataaacgaat gctcattgaa
     2641 gatatctaga ctcagagaaa atggcaaatc tgctacttct ttttctttta ataattcatg
     2701 cccacgttct agataactat ttatttcttg ttcatcttct gtaaaagctg tcattgtttc
     2761 ggtagggatg gctttggctg aatgcttaag gatttttttc tcttcatcga tggttaaatg
     2821 gacttcaccg acatactgcc cgtactttcc agcggctgct atttggacat cattgattac
     2881 gtgaccttct ctgaataaat gatgggtgtg cgatcctaaa ataacatcaa ttgctggtat
     2941 ttcttttgca atttggaaat catcctgaat cccgagatga ctcatcaaaa ctaaaacatc
     3001 cacttgtgaa cgtaaatctt cgactaattc tggcaaaata tcataaggat tccgtatgtc
     3061 ccagccattc ggattataag taagcggaaa tggagcagta aatgcaatta gtccgatttt
     3121 cgtctggtgt ttcgttgtaa tgattttata tggtttcgtc catgccggtg gctggagcgt
     3181 atttttatcg aataagttat ccaggatgat atcaaactca gcatgatcgt ataaatgatt
     3241 caactcttct ttggaatttc ctacgccttc attgtttcct atcgtcgctg catcataacc
     3301 aacttcattc atcagcaaga tattttcctg tccattcgtt gcttctgaca atggatgcca
     3361 acgatccaca aaatcaccta gatctactgc aatcgttgtc gttttttctt tcttttcgtt
     3421 ttctcgttta cgttgatcca aaaaccttct gatccttggc caattttcta aatgagaatg
     3481 cagatcattc gtatgtaaaa tcactatttt ttccatgtac cctctcgcct ctctttatct
     3541 ttatcatacc ataggcagct ttttcttcca ttgaaacaag ctctatttca gagtttttcc
     3601 tgccttgaag caaattgtat aagtacaata ttcgataaat cagtctggct aaaaaatcag
     3661 gaacattcat ttttacagta ctataaaaat aaaaaaaaca gacccgaaag tctgttgtcg
     3721 tttcattata atcagacaca tggcggaacc tgcttagtgc tgcttccttc cagacctgac
     3781 acgcttcaca agcccaccat tgtcctagcc tttcggcaaa gaatagtata ccttattttt
     3841 cattcgttga ccagtctttt tttaatttct tttttcgctg gcggagcttt cggaaaaagt
     3901 cagtcaaaat catcccacat tcgtcttcta aaatgccacc ttctacatat gcttggtggt
     3961 taaaccgctc gtcctccaaa agattcatca aggtaccggc tgttccgcct tttggatcat
     4021 acgcgccgaa ataaacttct gctacacgag acaaaatcat cgcgccgctg cacataggac
     4081 aaggctctaa ggtaacaaaa agtgcagcat cttccaagcg ccagcttccc actttttcac
     4141 aggcttcctt gattgcaagc atttctgcat gtgtagtagc atcttgcgtg gtttctctaa
     4201 ggttatatcc tcttccaatc acttttccat ccaatacaac cactgctcca atcggaactt
     4261 catgaagcat ttctgctttc tttgcttctg ccaatgcaag gcgcatccat ttttcttttt
     4321 ctactgcatc aagatttgta tttaccaatt acccttccct gcctttgttt tttcttgttt
     4381 tactttagca tatgataaaa aggctgtaac taactttttt ttctatggta aaataaatac
     4441 aagaggtgaa caagatgaaa atggataaat tacttgctct ttacccacaa gcacagaaaa
     4501 aaaactctcc agcatcagaa gcggatatcc tttcttttgc aattgatgat gcttttatct
     4561 ggatcaaaca agattcatta tctcaacaag aaaccagcct tttgaaagcg ttattccctg
     4621 taatcaacga tcaaaaaaaa cacccatggt atcgctatct ttttaaagat gcttcttgtg
     4681 ttcaagaaaa aagctttcgt ttgatccagc ttcacgtcga atcaaaagga gaattcttaa
     4741 aaaaagaatg gcaagatact attttggaat tatttcgcta ttctgctgat ttcttttttt
     4801 atacagacac agatgcgctc ttagtcgaac aaataaaccg tgattatctt gatgctactg
     4861 aaatcaacgg tatttttcta tctttagatg ctgattttga tacgacaacg tctgtattcg
     4921 ttggttcttt ccattcacct ggcaccgacc tcgtcccttt gtttgctgaa gaaagaaaaa
     4981 tttttttaac agagcaaaac aatctttata ctcacagccg tactttttct atgcaagatg
     5041 tggctttaca ttactataca aaagatactg taaaagatag taagttgatc aaaagttaca
     5101 tagaactgat caaacaaaat gaaatggaag tgatcattca agaattatgg aatgaattag
     5161 gcaatgtcag ctctgctgca aaaacactgt ttcttcatcg taatactcta aaatatcgaa
     5221 tcgaaaaatt tcaagaacag tctggtttca atctaaaaaa agccaacgat ttactgtttt
     5281 gctatctttt attgcttcat gaacataatt aaagatagat taaaggggtt gtgacaataa
     5341 ttttgtcaca accccttatt tcgaatgaat agtgttcaaa agctagtttc tcttacatca
     5401 ttttttcaac aaaatgcatt agccggtctt ttacatcttc ggttgaatct ttgattgaat
     5461 caccataaac agagattttc ttttttcctg atttgatttt tgctaacatt cccatcaaag
     5521 aatccaagtc actatctgaa agaccatcta cgatttctag taatttttca tttccatcaa
     5581 atttgtcata gacgaatttt tttactttcg tccgagtagt catatgatgg atcttttcca
     5641 ttacttttcc cgatacaacg actgctgtcg ctacactggc agcggctgct acgcttaatc
     5701 cgattgttac ttttgttgat gttttcataa gtatcagctc ctttttatct atctccatca
     5761 tagcatagac aaaaaaataa acgaactaat ccactcagtg aaatctcaat cctttaggga
     5821 aaaagttctt tactgttcct tttacttgtt tcccaaatcc gacaggtatc ttatctaata
     5881 ctagcaaaac ccatccttga ttcccatcac gttgaaatgt ttctcctgct gtgtaagatt
     5941 gccattcctt ttgagtgatc ggcaagcaag gtatattctc tatctttttt gtagcaagcg
     6001 ctaatgcata gctaggttca aatcgattct ttttgaaatc tcctaaatgc aaacctgtac
     6061 gtacgacttt taaaccatcg agagaagggg ctaactcagg aacttcccaa agatggtcgt
     6121 tgaacactaa aagtcttcca gtagcttcat aatgaaaatc atttgaaaac tccgtccaga
     6181 gtttttcctg ctcttttgtc atttgcactt tacttttttt tcgtgtcttc ttttctttat
     6241 gcatctgatt ttgtccatga aaagtcagct ttgcaacaaa atgtccttca ccctgatctt
     6301 tatgaggcca tatacgtatt gttttttcca aaccagctac gcttccccat tcagaacgtc
     6361 ctgaactaac ggattgagtc aaaggaatct cctcaatcgt tactggataa ttttctacaa
     6421 gccagctaat gatctcttca ttttcttctg gtgcaaacgt acaagtcgaa taaatcagtt
     6481 gtcctttatt ttttagcatt tttattgctg aagacaaaat ctcttgctga cgtttttgac
     6541 agtatagcgg agattcttct gtccactctt ttattgcatt tggatctttt cggaacattc
     6601 cttctcctga acaaggagca tcaaccacga tccgatcaaa aaagcccgaa aaatgaggga
     6661 caagttctgc gggtgcatga tttgtcacta ttgcgttcga aactccccat cgttctatat
     6721 tttctgataa aatcttcgca cgtttcggaa agatctcatt cgtcactaat aaccctttcc
     6781 ccttcatttg agcagctaat tgggttgatt taccaccggg agccgcacac aaatccaaaa
     6841 ctttttcacc gggttttgct gcagcagctg ttccaacgat cattgcactt ggttcttggc
     6901 tatattcata cccagcttga tggaggaaag actttccatt gacagtgcca agaaatccct
     6961 cattgctgta gggagcgggt tgtaattctt cgctatggta agtttggacc atgtccaatc
     7021 ctgccggttt tagtggattc caccgaaatc cttttttcac gcttccttgt tcaagcgcag
     7081 aaaaaaaatc ggatgcttct tcgcctaaaa gaagacgata ttttttgata aattgctgtg
     7141 gtaacgttgt cgcttcctcc ttcattccaa tgtttcgtta gacattttac aatctttttt
     7201 acgaaaaata aaggtggctg atctactttt tcatgttgct gcctaaggtg actgttcctt
     7261 taagatattt tccaagtatt catccgtcac ctcgttttta tcccaaacag cgttcatcat
     7321 ttcaagaaaa tcttgagaag aatcatctga gcgcaaactt cccaatgcat taagccatac
     7381 caattcaagc gacttttctt ctttgatctt cgtgtgacct ttgacatatg agaaaaatgg
     7441 ccgcttaaat agcgaatcca tgtctaaatc agattttgca atgatttcac gaatactttc
     7501 atggatagaa aaaaaatctt tcaataagta gacaatgctt aaaacatcat cggaactgca
     7561 ttcagctaag tagttttcaa aataaacagt gatttcttct aatatcttct cttttaaccc
     7621 gctgattgat ttgaaatgtg tataaatcgg gtatgtagaa caaccgcaga actctgctaa
     7681 ctctcttgca gtaattgact tcattccata ttcttccacg tataccatac ttttgaacag
     7741 caaatattct ttactataat ttgttactct ccccatcatt cttacctccg tctcttttca
     7801 tctacccata aataaataac ataaataatt ctaaaaatat tattgataat tatcaaaaca
     7861 tatttagtta tatccattaa aaatcaattt ttccgcctta aaaacaagaa tatcttgaca
     7921 aaatacccta ggaaataaac aatagaataa acaaggtaac aaaaaaatta aataacgtta
     7981 tataaaaaag aaggcgacac tctgtgagaa taacacagac tgaaatgact ttccactcac
     8041 agtttttgtc taactatata caaaaacaga ataaaaagga ggtatttatg ctaattgaag
     8101 caagaaaaaa agagttactt gttctacaaa tggtcattca aaaaaataat tgttctttac
     8161 aagaattatc caatgactta catattccaa aacggacaat caaagaactg atccgaaaaa
     8221 taaatgtatc actcaagcaa tttttattga ttgatgaatt tatttattct aatcataaag
     8281 gagagatcca aaccaaagaa accgatcaaa ctaaaaagtt agctgttttt tctaagttaa
     8341 aattatgcta cctaaaagaa tccaatcgtt ttaactattt gatgttacta atcaattatc
     8401 cacaaactgc tgtaccaaaa aaatatttac ttgaacaact ttatatatcg ccctcctatc
     8461 tcgaaaaact gacaaaacag ctcaatcatt ccttaaaaaa attccattta cggatcctat
     8521 ctgtaaaaaa ttgctgtact cttgaaggaa atgagttatc tatccgtctc tatctttact
     8581 tttttctttc agatacattt ggaggtaacg attggccatt ttcctcactt gaattaaatg
     8641 cactaaaaat gaacagtaca gatgagcaaa tagaaaaaat ttcaaaacaa gaaaaaaata
     8701 tctacttgct gttaacttta ttcatattac gaaacaaaca acaggcatat tttccaaaaa
     8761 cttcttctga aatcactgaa ttgatggact tattgcagca tacacatgat tattcagaat
     8821 actttacttc tttttcagtg agtcgccctt gtgaagagac agaaacagag agagcctact
     8881 ttaattattt tttctattgt ttttttccaa atcaaatctc ttttcgacaa aaacaggaga
     8941 ttggtttttt attttccaca agcaaaaacc ttatttgtcg acaagtcggt caattgatga
     9001 cttacttaac tcaacagttt cctctcaacc atttagaaaa taaaatacca atttattttt
     9061 attttcttgt gttggcagtt gtttttttcg aactgttggg tgaatccagc agtagttttt
     9121 ctacactttg ctttccagaa gccacgtcca atcattctag ttcttttata caggaaaaga
     9181 aattaagaga aaaaatcgat acaatttttt caaaaaatgg ggaaagaaac caaatcagtc
     9241 aataccttag tcaattgatc caacacttac tacaaacaga aacgaaagag cagttactca
     9301 tccatttgca gataaccaaa cagtttacag gaaattatca tcttcaaagc catttgcagc
     9361 agttatttcg caaagatgct gttaaaatta ccgcatattc agaacatgct gatttgatca
     9421 ttacagatca gcatgagaaa atttcagatg aaacggagac tttctatctg gatacaacgc
     9481 acaatacagt gttatttggc aagttaataa aagcggttca tgaactgtat atgaaaaaag
     9541 gttatgagaa caaaacaaag aggatgtgac aaaattcttg tcacatcctc ttatt
//
LOCUS       DAPBAF010000076         9511 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.078, whole genome shotgun sequence.
ACCESSION   DAPBAF010000076 DAPBAF010000000
VERSION     DAPBAF010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9511)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9511)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9511
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.078"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(57..992)
                     /locus_tag="RD451_002621"
     CDS             complement(57..992)
                     /locus_tag="RD451_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567827.1"
                     /translation="MNILNEKRYVWFAGKKYITTFKRLSELMQQTVKSAMPEGYKFNF
                     VQSSVSTESIYFSILSESRLFHFRISSHVKKTDVDIYTFRTNNYKNLNDLSRSISEYL
                     KGNSYLKIRFSHILILLPYLNENFTLIQVDKSFIASGNQGNMNITSNKTSRVLLALMG
                     YGILYRDDQNGQILINRAGRSLLMKYRKFIPEDFQNLQLENMRLEDLFRLAEDDKYRF
                     EVLKIQKNELLNKLYPENAIKAHFGDANHMYSWFIPKRFRGKINAGDQVKVLNRNSTD
                     VVMITDIYVEDEDIIKYMKPVIKLVNKNKGTRGAS"
     gene            complement(1551..1868)
                     /locus_tag="RD451_002622"
     CDS             complement(1551..1868)
                     /locus_tag="RD451_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HDT7567828.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
     gene            complement(1869..2123)
                     /locus_tag="RD451_002623"
     CDS             complement(1869..2123)
                     /locus_tag="RD451_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HDT7567829.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDIIQAKQEGNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            2482..2886
                     /gene="tnpA"
                     /locus_tag="RD451_002624"
     CDS             2482..2886
                     /gene="tnpA"
                     /locus_tag="RD451_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="HDT7567830.1"
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERIS
                     ESYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLWKE
                     MFWSKSFCLLTTGGAPIDVIKKYIQNQGNNHK"
     gene            2903..4051
                     /locus_tag="RD451_002625"
     CDS             2903..4051
                     /locus_tag="RD451_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDT7567831.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYE
                     EVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRF
                     KSKKNPVQSYTTNNQNGTIALIDSKFIKVPKLKSLVRIKLHRQPKGIIKSATISRHSS
                     GKYYISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDNNKFTSKMEKKLKREQ
                     RKLSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTDFLNKLSTEMIKNHDI
                     ICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRKIIKVDKWFPSSQICS
                     ECGHKDGKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLHSMGLA"
     gene            complement(4274..4492)
                     /locus_tag="RD451_002626"
                     /pseudo
     CDS             complement(4274..4492)
                     /locus_tag="RD451_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391850.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(4758..4952)
                     /locus_tag="RD451_002627"
     CDS             complement(4758..4952)
                     /locus_tag="RD451_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567832.1"
                     /translation="MMGFFLRFYIIELTGRLTVFFGNFAIKPFAEVTAHYICKWLDCK
                     NKIKKVFHYISSSPCQIRPG"
     gene            complement(5052..5138)
                     /locus_tag="RD451_002628"
                     /pseudo
     CDS             complement(5052..5138)
                     /locus_tag="RD451_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
     gene            6304..7344
                     /locus_tag="RD451_002629"
     CDS             6304..7344
                     /locus_tag="RD451_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HDT7567833.1"
                     /translation="MTDFKFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCRVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFVPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAEIESDISIVFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNYA
                     SSPSTITKDWLE"
     gene            8168..8500
                     /locus_tag="RD451_002630"
     CDS             8168..8500
                     /locus_tag="RD451_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HDT7567834.1"
                     /translation="MSYTGILSLKDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIG"
     gene            9119..9460
                     /locus_tag="RD451_002631"
     CDS             9119..9460
                     /locus_tag="RD451_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HDT7567835.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQKLTDNPIGFGLLPEDDEGNEWFKMTLTDDNGDELSVEDTWSYLSDYIVSV
                     EIIEFVADKEE"
BASE COUNT         3337 a         1466 c         1547 g         3161 t
ORIGIN      
        1 tatgcgtttt tttgttgatt taccaacatg tttagacatt tttctctagg aaaaaattaa
       61 ctagcaccac gggttccttt atttttatta acaagtttta tcacaggctt catatatttg
      121 attatatctt catcttctac atagatatct gttatcatta cgacatctgt actatttcga
      181 ttgagtactt tcacttgatc tccagcattg attttccctc taaatctttt aggaatgaac
      241 caactataca tatgattagc atcaccaaaa tgtgctttta tcgcattctc aggatataac
      301 ttattcaata gttcattctt ttgaattttc aaaacttcaa atctatactt atcatcttct
      361 gctaatctaa ataaatcttc taaacgcatg ttttctaact gtaagttttg aaaatcttcc
      421 ggtataaatt ttctatattt cattaataat gaacgcccag cccgatttat tagaatctgg
      481 ccattttggt catctctata aagaattccg taacccatca acgccaatag cacacgtgac
      541 gttttgttac ttgtaatatt catatttcct tgattacctg aggcaatgaa agacttatct
      601 acttgaatta gggtgaaatt ctcattcaaa tatggtagta aaattaatat atgtgaaaat
      661 cgaatcttga gatagctatt ccccttgaga tattcactga tacttctact caaatcattt
      721 aaatttttat aattatttgt acggaacgta tatatatcaa catcagtttt ctttacatga
      781 gaacttattc taaaatgaaa aagcctactc tcagaaagaa ttgaaaaata gatactttca
      841 gtagatactg aagattgaac aaaattaaac ttgtatcctt caggcatagc acttttaaca
      901 gtctgctgca ttaactcgga taatcttttg aaagtagtaa tatatttttt accagcaaac
      961 catacatatc ttttttcatt aagtatgttc actatctctc ctccattaat tatatttagc
     1021 atcaaatagt tattgtacct atattttatc ccattccttt taaaacaaga atacgtacaa
     1081 agtaaaatgt tgtaaatagt ctagcaggga tgtatatttt catgtaccaa cataatattt
     1141 aagaagtttc ccatagatat attggacttc ctcttttaaa acacaaaaat aaatactacc
     1201 ttatttaggt agtatttatt aaaagttacg tcaattttga ttaaaaatat actacttgaa
     1261 cctctcatga gtaaagtcac gaaatttttg ggaatagagc gtacttgata tcttattttt
     1321 tcactaatag cagtgtctct tattcaccaa gcgatccccg tagttcctac ggttcttaat
     1381 ttttctctag actaatgatt gtatctttag accttcggcc ataacatgga gcaaaataaa
     1441 aaggtactaa gtcttatata tcaatcttcg agtaaccgac ggttaacaac catatcgagc
     1501 ggcattaatc acccacctgt agaggatgag cgactttttc ctaattattg ttaaaagcct
     1561 agtttcattt gtttagattg gaaaatacgt cctacaagta tctctttttt ttcatggtcg
     1621 atccgataaa ataaggcata gcttttgccg atcacgatcc gatatgttgg gatatccatt
     1681 ccatagattt cggaaacttc ctcatgcata gttggaaaat ttttggttag ttctaaagcc
     1741 ttctggatcg cacctacaaa tctttttatg ctggctggag aaagagcaag ctcattttcc
     1801 cattcttcta ttatcgtttc aaggctggtc tgaaaacttt tagaataaac tagcgtgtac
     1861 tctttcatct attcactcca gccgtatttt ccgaaagctt ttaccatttc aatttctgaa
     1921 actgttaaac ctttctcaaa gtcttggaaa ctttcttcaa tcaatttgcg atcgtgttct
     1981 tttgctattt gagtagtatc taatatgaat aagttgcctt cttgtttggc ttggataatg
     2041 tctccgcttt ttaatccaag agagcttgga aggatcactc ccacgctatt gccgatcttt
     2101 ctaaccttta gttcttttcc catgttatca cactcctttt agtttttgat gaataaatta
     2161 taacatgtta taacaacaat tgccaacggt gtttcttaag ggattccact ccatattatt
     2221 attggacaaa ataagccact tagaacgctg aaaacatata caaacgatat caaaatacga
     2281 gtgaactact caccatacac ttccgttaac atccatttaa cagaattagg cagaagtcgc
     2341 ccatcctcta taggtgggtg atgaatgccg ttcggtatga gggttaccgt tggtaactcg
     2401 aagaccgaca actaaggcgt attgcctttt tattttgtcc catgttacaa tcagtctata
     2461 caagaaatga gttgatataa catggaatta gatacaaata atcattcagt atttcttctt
     2521 tattaccacc ttgttttagt aacgaaatat cgtagacaag tgattgatga tgaaatatct
     2581 gattatgcca aaactacttt tgaaagaatt tcagaatcgt atcacattac tttagtggag
     2641 tggaatcatg ataaagacca cgttcatatt atgttcaaag ctcaacctaa aacagaattg
     2701 acaaaattca tcaatgccta taaaagtgcc agctcaagat tgataaaacg tgactttcca
     2761 agagtcaaac aatttctttg gaaagaaatg ttctggtcta aaagcttttg tcttctgaca
     2821 actggtggcg caccaattga tgtgattaag aagtatatcc aaaatcaagg aaacaatcat
     2881 aaatagaaag taggtgaact ttatggaaca actaaaagca tacaaattca gaatctatcc
     2941 aacagaggaa caagaaatct tctttgccaa atcttttggt tgtgtccgta aggtctacaa
     3001 tctaatgctt gatgaccgaa aaaaggcgta tgaagaagtt aaaaatgatt cttctaaaaa
     3061 aatgactttt ccgacaccag ctaaatacaa gaaagaattt ccgtttttga aagaaattga
     3121 tagccttgct ttagccaatg cccaacttaa tttagataaa gcatacaaga atttttttcg
     3181 ggataaatcc gttggatttc cacgtttcaa aagtaagaaa aatcctgttc agagttatac
     3241 aacgaataat caaaatggta caattgcttt gattgatagt aaattcatca aagttcctaa
     3301 attgaagtca ttagtaagaa ttaagcttca tagacaacca aaagggatta tcaaatctgc
     3361 tacaatatca cgtcattcta gcggtaaata ctatatttct ttgttgtgta aagaagaaat
     3421 tatcgaatta cctaaaacta attccacaat tggtattgac ttaggtatta tggactttgc
     3481 gattctttct gatggacaaa aaattgataa taataaattc acgtccaaaa tggaaaagaa
     3541 actaaagcgt gaacaacgca aattgtctag gcgtgcttta ttggctaaaa ataaaggtac
     3601 caatctattt gaagctaaaa attatcaaaa acaaaaacgc aaagtagcta gattgcatga
     3661 aaaagtaatg aatcaacgta ctgattttct gaataagttg agtacagaaa tgatcaaaaa
     3721 tcacgatatt atctgtattg aagacttaaa cacaaaaggt atgttgcgaa atcataaatt
     3781 agctaaaagt atttctgatg tttcttggtc aaagtttgtg actaaattac aatacaaggc
     3841 tgactggtat ggacgaaaaa tcatcaaagt agataaatgg tttccgtcta gtcagatttg
     3901 ttcagagtgc ggacataaag atggcaagaa atctcttgaa attcgagaat ggacttgtcc
     3961 tgtttgtcat actcatcatg atcgtgatat caatgctagt atcaatattc tgaccgaagg
     4021 tctaagacta cattctatgg gattggctta gatccaatca tcaagaaccg taggaactac
     4081 ggggatagct tggtaaataa gagacaccgc tgttagtaaa gaaatacgct atcaagtatg
     4141 ctctattccc aagaagctcc cacttcaagc gttaagaacc gtcaggttta gctaagtggt
     4201 gagtagttca cgtaggtatt tttattatat atagatttaa catatgtcgg tcggttgatt
     4261 gatatagcta aagttataac tcaaccgaag ccgattcatc tacacgaata aagttgcgag
     4321 tgttctcggc taattcataa aaattgttat gtgttccata tagcaatact ggaataactt
     4381 tattttcttg aatctcataa gcaactctat acacggtgac cgcatactta aatccattag
     4441 accaattacc tgataaacct ccagtttttt gctcttactt aaatggatca atggcaattt
     4501 catcacaaac ctatagagga tgagtgactt ctgcctaatt acgttaaaaa atattgaaag
     4561 taactctatg tagcaaaaaa tatctagaat ttcatttcct caaaactgat cgatattgta
     4621 tctaaaaata tatactacct aaaataggta gtatatatta aaatatgtgc ttttgttaga
     4681 aaaatcaata cataaattat catatctgta tatgtcattt aggtatttca gttatgttat
     4741 aatagttttg ctgtctgcta ccccggccta atctggcaag gggaggagga gatataatga
     4801 aatacctttt tgattttgtt tttgcaatca agccacttgc agatgtagtg tgcagttacc
     4861 tctgcaaatg gcttgattgc aaaattgcca aaaaagacag taagcctacc cgttaattct
     4921 ataatataga aacgtaaaaa aaaccccatc agcctgcacg ctgatggggt ttggtgatat
     4981 aatgaaatac ctctttgtta ctcataatta taccataatt agtcacgaat gcaaccaata
     5041 gaaaaaacta cttagaacgg tagatcatcg ctaataacaa tgcattgtcc accaaatgga
     5101 ttttgtgaag cattaaatac attgttatta attgtcgctg cttttaacta ggcctctccc
     5161 cttctattat aaaagaagat atatatcatt tcttaattac ctactacctt aaaccaaaat
     5221 ttaagtacta cctaatttaa gtagtactta aacaatctaa aaaatagtta tcccaattgt
     5281 tatgctttta taatacgatt atttgtaaca aaatgaatat tatataatta aacactacca
     5341 tatttaggta gtgtttaatt attagcaaaa caaaaaatat ttattctatt ctcttaactt
     5401 caactaagtt atgctgcaca cctttatata aatcatatgc aactcattag ctagacaaac
     5461 tacaagcatg tagttttatc tgttaattat gtactaccta aataaagtag tttataatta
     5521 gcaagtatat atatttaaaa atttaagatt aattttttta tgacttgtac aaatttatct
     5581 gatattctct tattaagaac tacctaattt gggtagttct tattttttac attttaagta
     5641 gtatttaatt gcaatttggt agtatttttt tattatctta ttcttagaac ggtagtactt
     5701 aatataaata taggtagtat ctaatttaag tattaatggt agtatctaaa ttaacaggta
     5761 gtatgtaact actttaaagt aatttttttc agattaacac agtagtatct tattaaataa
     5821 gttaatttta atggtagtac ataattatta tatatatctg acattggtag tacttattgt
     5881 attttttagt agtatataat ctattgtttt ctagcctaaa gccttgtctt ataagaataa
     5941 tataatatat actactgaaa taaggtagta tatattacta gtaatggtag tatgttttat
     6001 atgcataagg tagttcttaa tttatttttt gttttgacac tggtagtact taattatctt
     6061 taattttaaa actaaatttt attcatacgt ttttctggta gtatttaatt ataaataata
     6121 tttatttaaa gtagttctta atgactttaa aggtagtaca taattcattt tatttctgat
     6181 tttaggtagt atttaattaa aaaacagttt taatgcgttt gcatttttta tttatctttg
     6241 ctattttcga aaagagtagg taattttaca taaataaaac aacgtgaaag tagaggatct
     6301 acaatgactg attttaaatt ttttaaggcg gatagagttt acaacgaatt attttatcaa
     6361 tttccaaaag tctttattgt ttctgacgaa tacaaaaaaa tgaaagattc aactaagatt
     6421 gcctatatgc ttttaaaagc aagattagag atcgcaatca gcaaacggca aatcgatgaa
     6481 gaaggtaatg tttattttac ttatacgaca aatgaactat gtagagtatt aaactgccaa
     6541 aaacaaaaag cgatagcaat caaaaaagag ttggaatcct ttggtttatt attacaaaag
     6601 cagatgggat ttaacaaaca gttagggaaa aataatccta atagactata tctagcagaa
     6661 ttaaaagtct cagaaaatga tatctactta ctcgaaaaat ttgatagaga gaatagggaa
     6721 aacgttgata aatcagaggg tatgaaaatc atacccaccc tcgacgaaaa atcagacgct
     6781 gaatcccttg gggctcaaga gggtatgaaa atcataccgt gccaaaacgt tgataaatca
     6841 gagggtatga aaatcatacc agaacttaat aataatatat tagacactaa tagacacaat
     6901 atagacactg aaaaagaccg cctacaagat caattgttgt tagacaattt tgagacaatt
     6961 atgacaaacg acagcattgc tacgtttgtc cctgaacgag tattaaattt gataaaaaca
     7021 ttttcttcaa gttacagtga agctcaaaaa accgtccaga ctattcataa tgcaaagaaa
     7081 aaagctgaaa tagaaagtga tatttcgata gtttttgaag aactcgatag ttattatgtc
     7141 aatgcagaac aagaattata cacgacactg ttaaaagcct atcaaaaatt aaaaaccgaa
     7201 aaagtcgaaa atatccagaa cctgattttt gtctatgtaa aaaattggtt tatcgaaaaa
     7261 ccaatagctg ctaaagtatc aagtgaaaaa cgtttgaatt atgcaagctc cccaagcact
     7321 attacgaaag actggttaga gtgaaacttt actgacaaag tgattgttgc ttcatggagt
     7381 aacattaaaa ttaaaaattt tttattattc taattatatt acgaatatta caaaataata
     7441 gctattttaa tagaatttat aagttaaaat attatgataa aaatcacaaa cgtagccttt
     7501 tacgtcataa gtgttaaaag aaataattaa tttcaaatat agaaaaggga acgtatgttt
     7561 gcatactcct tttttttgag ttataataat acgcgaagag agataatttc attatttaaa
     7621 caagctaaaa atcttgatat tacttctttt caggcaatac gaatattatt cgcttacatt
     7681 ttttgtataa atttaattgt ctgctatgct tgtgatgaat tgattttcgt tttgcacttt
     7741 tggatgataa atttggacaa ttgaaaatac aaaaaaaaga aaggcggtat gaactcggaa
     7801 ggctggtaac cttcgtcagc gttcatacac ggcattaaga tttggccctt aatgcgttaa
     7861 cctttcagtg ttacggtatt acccgcaatg gatttagtat aacagatatt caaaagtgat
     7921 accacttttt ttggctgtgt taaggttaaa aatacgtgat attacgatga atctatgcct
     7981 aagcataatg ttataaaaat gtccgtgtgg ctctttgccg tatgacgaac gctgaaatta
     8041 gagggaacgc atgtttggat gcgttccctc ttttttgttt gtcatgaacg aaaatcaatt
     8101 ctctattttt gaaaaataac aagaaaaact tgttaaaaat atttaaagaa attgggtggt
     8161 ttattttatg tcatatacag gaattttgag tctcaaagat atttgtcact acggtaaacg
     8221 gtgtaccgct acagagaaaa tcacgaagaa actatcaact ggccaaagta aaaccgttgt
     8281 gcagtgtaag aaatatataa tccagaaaga caaagtctca gaggaaatga tttattacat
     8341 tgggaaacaa aagcaaataa ttttaaaaga tcctatcccc ttaaaagagc tatatccaac
     8401 aatcaaacat gtttatgacc aaaacggtgt actgattggt cgaagaaaaa atggagtctt
     8461 gcgttgtacc gcaaaaggga tggggcgttt gatcggctga attgatcatt ctcataactt
     8521 gtattttatc gtttttcgct tgcttgaaaa tattgtcgag acttctaaag gaacttagag
     8581 tcactagaaa aataaggagt agacttgatc tatcaacaat tcccttcggg gagtgacggg
     8641 gtaggtttta acgattggta acgtaaaaaa ttggtcaatc gagtaaatgc gcttgtttgg
     8701 atagtggtga aatgaatttg tgtaaataat aagcgcagag taaacaagag ggaatttaga
     8761 agttagacaa gttagaatag cgtctagatt aatcatgagc agctactaag ggatctagac
     8821 tttgacgcaa actcatggaa taaggagtag gtcttctcgt aatggggagg acgcacaaga
     8881 aattgtgtcg tgtgctgcag tacatgtaga tacttgcgag gacgttgatt attggatcaa
     8941 tcgagcattt accgctgtct actagggttt ctcgtttcgg acgccataaa cgagtcgaaa
     9001 ttttttatgt atttttaagt aaacgaaaaa cgataaaata tgaacaagtc ctgaataaag
     9061 tgaaaaaatt gatataaaac atagagaaaa tgaaatttac gtaatggagg aatgacaaat
     9121 gaaaaattat gatccgaata tacgattggg cacacatact attaaggttt ctttccaacg
     9181 ttgggattac aaaggatttg tgacgtttag aaggggcgga aattgtaaag gattagatgt
     9241 tttagcatta gacgaggatg atttatacga tcaaaaattg actgataatc caattggatt
     9301 cggcttgcta cctgaagatg atgaaggtaa tgaatggttt aaaatgacgc ttacggatga
     9361 taatggagac gaattatctg ttgaagatac ttggtcatat ttgagtgatt atattgtcag
     9421 cgttgaaatc attgaatttg tagcggataa agaagaataa aaactggagg aataaatttt
     9481 acagataaag gcttagaagg agtcacgacg a
//
LOCUS       DAPBAF010000077         9416 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.079, whole genome shotgun sequence.
ACCESSION   DAPBAF010000077 DAPBAF010000000
VERSION     DAPBAF010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9416)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9416)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9416
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.079"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(<1..366)
                     /locus_tag="RD451_002632"
     CDS             complement(<1..366)
                     /locus_tag="RD451_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002606082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HDT7567836.1"
                     /translation="MINFSIKELNAFAVIGQEVELTNYQKKNIQISTQFWRKFNSSLK
                     KAYLSQSGNWVKYAFMERRNGKLYYFCSIPQRTITPEGFLYKEIPSYKYLVVEHIGAM
                     DKIYETYGKIYEEIIPSTSY"
     gene            complement(363..605)
                     /locus_tag="RD451_002633"
     CDS             complement(363..605)
                     /locus_tag="RD451_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3781 domain-containing protein"
                     /protein_id="HDT7567837.1"
                     /translation="MENELLENLGRLHTTELGVIRIKKNLSLNVENVIEWCKEKISLS
                     NAEITRKGKNWYITIDNCIITVNAYSYTVITAHKVK"
     gene            complement(1151..1681)
                     /locus_tag="RD451_002634"
     CDS             complement(1151..1681)
                     /locus_tag="RD451_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HDT7567838.1"
                     /translation="MRKVVLFIAMSLDGYIADGNGGVAWLNGHGNDNENIDTYTEFTK
                     DIDTVLMGWNTSHQVVTELSPQEWVYNKFTTYVLTHKECNSSQQIHFTSENPVLLLER
                     LKQEAGKDIWICGGANLVQQLVSKNMIDKYYISVIPTLLGNGVRLLGNIDREIKLRLC
                     KTQTYNGITDLIYMRR"
     gene            complement(1863..2519)
                     /locus_tag="RD451_002635"
     CDS             complement(1863..2519)
                     /locus_tag="RD451_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HDT7567839.1"
                     /translation="MNKEWSELNKTMQAQIKKKDTYKRGIDTLLTLRSQLIQTLVSFK
                     EELCREDFNSIPFINADGYHSKTIAYSIWHIFRIEDIVVHTVINEDEQVFFAGNYQER
                     INSPIITTGNELMKQQIADFSKQLNLEELYLYIFEVWESTEKMLERLSYDELKRKIPK
                     ERKGYLESLNVVNDNEKAIWLIDYWCNKDICGLIQMPFSRHWIMHTEACLRIKNKIHS
                     "
     gene            complement(2646..3119)
                     /gene="dfrF"
                     /locus_tag="RD451_002636"
     CDS             complement(2646..3119)
                     /gene="dfrF"
                     /locus_tag="RD451_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrF"
                     /protein_id="HDT7567840.1"
                     /translation="MIGLIVARSKNNVIGKNGNIPWKIKGEQKQFRELTTGNVVIMGR
                     KSYEEIGHPLPNRMNIVVSTTTEYQGDNLVSVKSLEDALLLAKGRDVYISGGYGLFKE
                     ALQIVDKMYITEVDLNIEDGDTFFPEFDINDFEVLIGETLGEEVKYTRTFYVRKK"
     gene            complement(3538..3756)
                     /locus_tag="RD451_002637"
                     /pseudo
     CDS             complement(3538..3756)
                     /locus_tag="RD451_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173391.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(3787..5001)
                     /locus_tag="RD451_002638"
     CDS             complement(3787..5001)
                     /locus_tag="RD451_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HDT7567841.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
     gene            complement(5342..5584)
                     /locus_tag="RD451_002639"
     CDS             complement(5342..5584)
                     /locus_tag="RD451_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HDT7567842.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
     gene            complement(5616..6173)
                     /locus_tag="RD451_002640"
     CDS             complement(5616..6173)
                     /locus_tag="RD451_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HDT7567843.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            complement(6186..6374)
                     /locus_tag="RD451_002641"
     CDS             complement(6186..6374)
                     /locus_tag="RD451_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HDT7567844.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            complement(6387..6953)
                     /gene="amaP"
                     /locus_tag="RD451_002642"
     CDS             complement(6387..6953)
                     /gene="amaP"
                     /locus_tag="RD451_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HDT7567845.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
     gene            7370..7543
                     /locus_tag="RD451_002643"
     CDS             7370..7543
                     /locus_tag="RD451_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567846.1"
                     /translation="MMKRLYYSLIITIGYLIVSNLGNMVFGISKEFSWTTTLWESLFF
                     FIFVFLLQNYRKK"
     gene            8184..8657
                     /locus_tag="RD451_002644"
     CDS             8184..8657
                     /locus_tag="RD451_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HDT7567847.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            8666..8893
                     /locus_tag="RD451_002645"
     CDS             8666..8893
                     /locus_tag="RD451_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7567848.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
BASE COUNT         2879 a         1847 c         1368 g         3322 t
ORIGIN      
        1 atacgatgta ctaggaataa tttcttcata aatcttgcca taagtttcat atattttatc
       61 catagcacca atatgctcca caaccaaata tttataagac ggtatttctt tatacagaaa
      121 gccctctggg gtaatggttc tttggggaat agaacagaaa taataaagtt ttccatttct
      181 tctttccata aaagcatatt ttacccaatt tcctgattgt gaaagatacg cttttttcaa
      241 actactgtta aactttctcc aaaactgtgt actaatctga atattctttt tttgataatt
      301 agtcagttct acttcctgcc caataactgc aaatgcgttt aattccttta tagaaaaatt
      361 tatcatttta ccttgtgagc agtgataacg gtataactgt acgcatttac cgttataata
      421 caattatcaa tcgttatata ccagtttttt ccttttcttg tgatttccgc attagaaagg
      481 ctaatttttt ctttgcacca ttcaattaca ttttctacat tcaaagataa gttcttttta
      541 attctaataa cgccaagttc agttgtgtga agtcttccta agttttccag taattcattt
      601 tccatatttt gatacctcat ttttcagcaa atttatttgt atgttttata ccccaattat
      661 aacattctca tatcagcact acaataaaaa taattaagca ccaataatct tattgaacat
      721 ctccaaccgt aaatctttca caccatcagt gataaacact gagctgacag caattacgac
      781 aactaccata attgcctgca cttaaatttc tgcaaaagaa aacgacaatc aatttcttat
      841 tttttgaaat caactgtctt tctcatattt actattcaat tttcatagtg atataggtac
      901 aatttatatc actactgtaa aaatggggtt ttgccttata aatacagcgt tttccgcttg
      961 ttagtgtata gtgtttcttg ttttttgtgc cccccttgtt agataacggg ggctttgaac
     1021 ggctcgcaag ctcgccgaac cgccgaagcg aaccgccccc ttgcaagcat ggcggaaaaa
     1081 tcttaaggat tttcccgcca acgtggtcgg atcgctccgt cggtttaaca gcttttctgt
     1141 ttctctctag ttatctacgc atataaatca aatcggttat tccgttataa gtctgtgttt
     1201 tacaaagcct taactttatt tccctgtcta tgttgcccaa aagacgaacc ccatttccta
     1261 acagagtagg aataacagaa atgtaatatt tatcaatcat atttttgctt accaactgct
     1321 gaacaagatt tgctccgcca caaatccaaa tatcctttcc tgcttcttgt tttagccgtt
     1381 ccaataataa aacaggattt tcacttgtaa aatgaatttg ttgggaagaa ttgcactctt
     1441 tatgtgttaa tacataagtt gtaaatttat tatataccca ttcttgcgga gaaagttcag
     1501 taacaacctg atgagaagta ttccacccca ttaagacagt atctatatct ttggtaaatt
     1561 ctgtataagt gtcgatgttt tcattgtcat ttccatgacc atttagccaa gctactccac
     1621 cattaccgtc cgcaatatat ccgtcaaggc tcatggcaat aaataaaact acttttctca
     1681 ttttttctct tttataaata caaacaggaa tttatttctc ttttttactc ataagggaac
     1741 aactgattgc tacaaataaa cccattaaaa tccatggaaa tgctgctctt ataaaatcac
     1801 taaccatact ttattcctcc ttaaattcca atttccttag ttctacaaac tgaaattttt
     1861 gcctatgaat gtatcttgtt ctttatacgc aaacaggctt ctgtgtgcat aatccaatgt
     1921 cttgaaaacg gcatttgaat tagtccacaa atatctttat tacaccaata atcaatcagc
     1981 caaattgctt tttcattgtc gtttactaca ttcaacgatt ctaagtatcc ttttctttct
     2041 ttcggtattt ttcttttcaa ttcatcataa gataaccgtt caagcatttt ctcagtgctt
     2101 tcccatactt cgaaaatata taaatataat tcttccagat taagctgttt tgaaaagtct
     2161 gcaatctgct gtttcatgag ttcatttcct gttgtaatga taggtgaatt gatacgctct
     2221 tgataattgc ctgcaaaaaa tacttgttca tcttcattta tcactgtatg cacaactata
     2281 tcttcaatgc ggaaaatatg ccaaatagaa taagcaatcg tcttactatg ataaccatca
     2341 gcgtttatga aggggattga gttaaaatct tctctgcata attcttcttt gaaagatact
     2401 aaggtttgta ttaactgact tcgtaaagta agtaaagtat caatacccct cttataagta
     2461 tctttctttt ttatttgtgc ctgcattgtt ttattaagtt cagaccattc cttattcata
     2521 ttcaatcctc tctcaaattc tgattttatc gccccataca aactggaatt tgtcttacaa
     2581 caatttatat atgcataaaa agcaatatat ttatgaaaac accctaaatc caaaatttac
     2641 tcaattcatt ttttccttac ataaaatgtt ctcgtatatt tcacttcctc accaagtgtt
     2701 tcccctatca aaacttcaaa atcattgata tcaaattctg gaaagaatgt atctccatct
     2761 tcaatattta aatctacttc tgtgatatac attttatcta ctatttgcaa agcttcctta
     2821 aatagtccat atccaccaga tatgtataca tctcgtcctt tagccaataa taatgcatct
     2881 tctaatgatt taactgaaac taaattatct ccttgatact ctgttgtggt ggaaacaaca
     2941 atattcattc tattaggcaa cggatgaccg atttcttcat aagactttcg ccccataata
     3001 accacattac ccgttgttaa ctctctaaat tgcttttgtt ctccctttat tttccatggt
     3061 atattaccat tcttgcctat aacattattc tttgacctcg caacaatcaa acctatcatc
     3121 tatttcatcc tccataatat gatgtcgtac ctgtgattcc atcaagtgca ccacatctta
     3181 acaaactcaa aattatctcg aactaaccag ctcgacaaat tccttttttg tcttcatctg
     3241 cattatatca tattgttata agcattgcca tttcttttct gcttttgaaa agttacttat
     3301 cagcctatgt tttgtaaagg gtgatattca gcatttctca cgcaacaagc ccttgacaaa
     3361 ccatagacta ataagtttta aggtaatcaa gcagaaatga aatagtctgc tgtttcacgg
     3421 caacaaaaaa gagataccaa cacacttatg tagtatctct tagtctagta gcaatattct
     3481 tttgtttgca agcaggtaaa catgggctgt ttcttaatat ctttttgttt gggaaacacc
     3541 tttttcccat cctttcaccg ttgccatctc tgctgcgcac aatgccacag ggataaacca
     3601 tagcaaaccg cctaataaca agaaaaatac taagctgaag cctgaggtcg cgaatgtggg
     3661 atattcatat aatgaaacga ccattgagat ggtcatagcc aaaaagccaa agaacgttaa
     3721 tttttttgca ggaattttcg ttttgctttg ttgcatgaat cttcctcttt tctatttgaa
     3781 tttgtttcaa ttgagtttgt tgccaaagaa gaaaaagtcc aatccttctt cttgttcttc
     3841 ttttgtagta gtgatcgttg taaagtgcat cgccgatttt aaaatcactg ttgtcagcac
     3901 ataggcatac acggcagtaa tgatgacacc aatcacttga atccctaaga agtaccagct
     3961 gcttggattc gttagtaaat ggctgttaga tgcaaagatc cctatcagaa tcgtacctgt
     4021 gaatccgccc atgccatgaa caccccacac atcaagtgca tcatcccatt gtttcttttt
     4081 acgaaaatca acagcagcat gacagacgat acccgcaatg atcccaatca gcatggcact
     4141 ttttgcttct acataaccgg cacaaggcgt aatggctgcc aatccagcaa cggatcctgt
     4201 tagtacgtcg acaaaatcaa agccatttcc ttttactttt gcaatgatca gccaagtaat
     4261 catcgcaaat gcaagagcga tgaatgttga accaaatgca ttgactgctt gttcatctgc
     4321 tcgaagtgca ccaccggaat taaaaccgaa ccagccaaac caaagcagtc ctgtaccgat
     4381 agcagctgcc ataagactgc tatgctgact tctttctcct aaaggaatct ttctttgacc
     4441 aagtgtgagg atacatgcta aagagccgaa tccagctgtc gtgtggatga ctgctccacc
     4501 agcgaaatct ctaaatccca tctgatccaa aaatccgcca ccccatatcc agtggcaaac
     4561 agggaaataa atcagcagat tccaaaaaat aacaagtata atatagcctt ttaaattcaa
     4621 tctccctgca aaagctcctg tcatcaaagg aacggtaatc acgataaaca tcagttggta
     4681 aagaaagaac attaaaaatg gaatcgttgc accatgaaac atgttgggga agcttgtaac
     4741 atgtctcatc aaaaagaaat ctgccgggtt tccaataaca ccgccgatat cccgtccaaa
     4801 ggccaatccg aatccaccaa atacccacat aatcgttgtt atcccaacgg agagaaaaga
     4861 ttgagacatg atcgttagta tattattctt ccgtgctaat ccgccgtaaa aaaaagctag
     4921 accaggagtc atcaggcaaa ccattgctgt acataaaatc atgaatgctg tatctcctgt
     4981 attgataggt aatgtattca tttttttcgc ctcctttcta cgattacgag tataaaagaa
     5041 ggtgtagttg tttttttctt ctgttttttt gaattaatac ttgcatttat aaaagacaga
     5101 caattaataa aagcttgatg tgttgtgctc tttttcgttt ttcacacaaa taaagacaaa
     5161 aaataaacgg tcttcttttt atagaaaacc gtttattttc gtcttttttt atttttaaag
     5221 atattttttc ataaggaata aagaatactt catataaaat atataaaaaa gaaccgcagc
     5281 gagtgtcgct acggttctca aatttgttct tcatttcaac ataagttttt cttcaatttg
     5341 cttataattt acgtgcaaag aatgaaacga ctaatactaa aatgattgca ccgatcaatg
     5401 atggaatgat agccattcct gcaattgttg gtccccaagt tcctagtaaa gcttgtccaa
     5461 ttgctgaacc tactaaacca gcaatgatgt ttgcgatgat ccccattgat gatcctttat
     5521 tcgtgattgc tcctgcaatt gctccaatga taccgccgac gattaatgcc caaataaatc
     5581 ccattttaaa ttcctcctaa ctgacttctt acttcttatt gtacacgtgg ttcgttattt
     5641 tctttgactt tttgtgcacc tttgcctaca gcagattttg ctttatctgt ttggcgtgaa
     5701 gcaaattgtc ctgtggattt tgctgcttct gttactttgt cttgtactgt ttcttgatct
     5761 ttttggtatt cttcttgtgt tttgatgtct gcaacattca cattcacttc gataacatct
     5821 aaatgtgtca tattgtttac ttcagtactg atcaattctt tgatttggtt gtaaatatct
     5881 tcgatgtctt taccgtattc tacgatcaca tctagatcca cagctacttg tttcttacct
     5941 acttctgtat tgatacctgc tgttacgtta tctgtgttga ctaatttttc agccatattt
     6001 gagaaaaatc cgccatctaa tgtcaataga ccatctacat ctttcaatgc ataaccgatg
     6061 attttttgga tgactttgtc ttcataagtc aattcaccat tcatcatgcg gttttctcct
     6121 ttttcatttg ccaaaactga tccatttgtt gtattcatgt ttttgttttc catctttgtt
     6181 tcctcctatg atttaaaaaa ttgatcaact attcctgact gtttcaaata aaaaccgatt
     6241 cctgcgccaa ttgctgtcat gattatgatc aacaatgtct tgaaaaatcc aatcgttaac
     6301 cataaaacag ctagcagtag tccaagaccc ccaaagataa tagggagctt gtatgctgaa
     6361 aatagttctt tcattatttg gccctcctat tccactcgag agtgcttgta gtctcttgta
     6421 tcttcttgtt cttcataacc gctgtatgtg actgccactt tgaccgtttc ttttgttccg
     6481 agtactttag ttacttcttc ttcgatatct tgcatcaata cacctgtttt ccctactaat
     6541 gaagaagttc gtttcaagtc tccgttgaca tggatatgga ttcgattttt cgttgaacgt
     6601 atccgtactt taggtgaatg aatgaactct tcttcgtgta aatgggaacg taccaaccct
     6661 tcgatcgctt ttttgtcgat tgttagtttg ccatcttccc gtttcataac gaaagttcct
     6721 cttgactttg gatagaaaag aacgactagc aagatgataa tagcaagaac ggcaaatact
     6781 acagctgccc agaaaatata ttgttgcatg tagtaattcg ttaaagtaaa gaagcgaaat
     6841 cgttccaatt gttcaggcat aatatacggc gcattgatca acgcaatcgc tagaaatact
     6901 gaaagtagca gtaaactcat gataacaccg attattttta accccttatt cattttccac
     6961 ctcctataaa cttattttta ccctgtaaat aactctaccg acaatcacag tatagatagc
     7021 gaacagttag catagcatca gtaaataaag cgctaccaaa cattgctgga tcataacggc
     7081 gttttattgc cagtctgata ctgaaataac aattgcttac ttattctcta tttacttttg
     7141 attgctggct atacttaaag gatattattc aagattaaaa attgcaaaga ttatgctcag
     7201 ttattattac aagattctat ttatttatta aattttttcg gagaattaaa aaatacaata
     7261 aataacttta gttactttaa tgcgttctta ctttattttt atattatcat ttttcttatt
     7321 cacttctttg gtttatacta ttcttataaa taaaaacgag gtatgtccta tgatgaaaag
     7381 attgtactat tcattgatca taacgattgg ctatttgatt gtatcaaatc taggaaatat
     7441 ggtatttggt atcagtaaag aattcagttg gactactaca ttatgggaat ctctattctt
     7501 tttcatcttc gtatttttgt tacaaaatta tcgaaaaaaa taaacatgtg ccatctatct
     7561 gttggcacat gttttaggat ttatggtact ttttattcgg caatccattt tatttttcta
     7621 cttcttctta atacctctaa cacttttgat ttataaacta atccaatgca tctacttgcg
     7681 cttattaagc tatttcagct agatagtacc accccatgcg tcaatgcttg attttccttt
     7741 tgtataacat tgtataagca ataaaggaca aataagtggt gattacacca aaccattgaa
     7801 taagaaaaat tctgatacgt aaataaacat gaacttgaaa aaattaatga atcggttagc
     7861 tactacgtag ttgtcttttt tctcatacag ttctgttaac ttacacttct cttcgctaga
     7921 taataaaaaa tcctccaact gtattgtcca atataatccc aggcatctaa actagcatta
     7981 tagaagagac acacatagaa tctaaaataa ctggttttaa atgtttctta caatcaaaaa
     8041 aagctgttaa atgcactcca caccttcata ctctatcatt ttttataaac gatatatttt
     8101 tattgttttt cgataaaaaa atagttgttt tacaataatt attctgctat attttagcta
     8161 tcaaagataa aagagggata aaaatgaaat ttaaaacatt gctattaaaa tttgtcgttt
     8221 taggtataag tgccgtattt attttgttcg gcgtactttt ttatactcag atcgctacaa
     8281 gcgaaaaagg attcaatttt gattggcaga ccacattatt tgtttctgtc atttactttg
     8341 cccttctcct agggatcgtt attgcttatt tcttattgaa actattgaaa aaaatcgaag
     8401 ataaccaagc tttttccact caaagcttaa acatactaaa aaaaatcgaa cgaaccattt
     8461 tgtttattgg tttcgccttt tttggcttac ttcctaaatt tatgaaagta gcggatttag
     8521 acgatgctcc aggtttgatg ttggtaggaa tcgctgtcgt attcattcct tttgcagtat
     8581 acacattaac aagcgtgctg gaaaaactgc ttgaacatgc gattttactt aagacagatc
     8641 atgatttgac agtgtgaggt gcgacatggc aattatcgtt aatttagatg tagtattagc
     8701 tcaaaaaaaa atgagtgtga ctgaattgag tgagaaagtg ggcattacga tggcaaacat
     8761 ctctattcta aaaaatggaa aagcaaaagc catccgtttt tccactctcg aaaaaatctg
     8821 ccaagttttg gagtgtcaac caggtgattt gttgacctat aaaaatgact cgaatactat
     8881 accagaagaa taaaataaag tagaacaaac agtaaataaa aaataatctg aatgatagat
     8941 gtgtgagact tttagaagtt atttacgtct attattcaga ttttttattt cgattgaata
     9001 ccgttttatc tataaataag atatgtactg actcatacaa agggggcctt ttcttctcca
     9061 tgtactatca cttttcctga tacaactggt ttcctgttac gttgtagttg gatctgcttt
     9121 tagtataata ctttattcat tccaccagac tgatagcagt ttgagcagtc taaataatca
     9181 tgtagtatta caggccattc tgtttcatac cttgaagtgc ttaaaacttc agctaatggc
     9241 ccattgtgtt aactcttact ccattctttt ttagtaagct cccatatata ctgtaaagcc
     9301 ttctatatat tatgtcatgt tgctttttaa catttactat gtagttttga taaaatgatt
     9361 tgaataacag tgatggacaa ttctttttta tttttaacat tattttgata ataatg
//
LOCUS       DAPBAF010000078         8857 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.081, whole genome shotgun sequence.
ACCESSION   DAPBAF010000078 DAPBAF010000000
VERSION     DAPBAF010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8857)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8857)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8857
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.081"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(54..347)
                     /locus_tag="RD451_002646"
     CDS             complement(54..347)
                     /locus_tag="RD451_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis protein"
                     /protein_id="HDT7567849.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEIDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
     gene            complement(375..1040)
                     /locus_tag="RD451_002647"
     CDS             complement(375..1040)
                     /locus_tag="RD451_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HDT7567850.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            complement(1180..1812)
                     /locus_tag="RD451_002648"
     CDS             complement(1180..1812)
                     /locus_tag="RD451_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7567851.1"
                     /translation="MIKVLLVDDHEMVRLGVSSYLSIQEDIEVIGEAENGRQGYEKAM
                     TLRPDVILMDLVMEEMDGIESTKAILKDWPEAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNEPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            complement(1819..2886)
                     /locus_tag="RD451_002649"
     CDS             complement(1819..2886)
                     /locus_tag="RD451_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDT7567852.1"
                     /translation="MMGKISRAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLLAISLGVGLIVFLLLSLIQKTKYGKIEEKLRALSSGNYESKLLLLP
                     IPSASDDLYIKDIDKEITKIKEKMIEVSSELQIVTSRPQYVDGQTKEEILELERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWDVEDVKLSSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVEIKVPLMKEA"
     gene            complement(2883..3614)
                     /locus_tag="RD451_002650"
     CDS             complement(2883..3614)
                     /locus_tag="RD451_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HDT7567853.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKHPRTKFQNFQLILGSLVIFFSLVNSPALWMMAVFAVLFIGLKDVEISGIDLTKNAF
                     WRKKQIMMIQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAVISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKIYSS
                     DYDENPRRLKIITNTLIGDVEVIRI"
     gene            complement(3783..4262)
                     /gene="greA"
                     /locus_tag="RD451_002651"
     CDS             complement(3783..4262)
                     /gene="greA"
                     /locus_tag="RD451_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HDT7567854.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGE
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            complement(4398..5573)
                     /gene="mltG"
                     /locus_tag="RD451_002652"
     CDS             complement(4398..5573)
                     /gene="mltG"
                     /locus_tag="RD451_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HDT7567855.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELHQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVEKYVNNS"
     gene            5777..6946
                     /locus_tag="RD451_002653"
     CDS             5777..6946
                     /locus_tag="RD451_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HDT7567856.1"
                     /translation="MKKGKHAKKRKYSFLMIVVVLFSLSAFSTGTILGWQFYNNEHSQ
                     IVAHAQSAQKKLILTTNEQQLVEKIDQLLRKNDYIGSIYVKKNNRIIMEKGYGYANKL
                     TQQPNDPSLYYQIGSVQKALTTLLILKQVERGHLSLDTKLAQFYPQIAGSQQITIRDL
                     LYMRSGLHRTASPTIPMTDEEVVQFAIQHLKFTDYQTSHYDSLNFTILTGILIKLTNQ
                     PYEKLLTDDIIEPLGLQHTKFYDQVKNSSNHALSYQMSKEDDYFKPLTESETEIHNEL
                     GTGNISMSVYDLNTLFTQVLSGKLVSKDLLFSLWRENANGHPYSGGVYSGDNYILSQG
                     NIDSFDTSAIFSKDSQDAIIMESNIKADKTIKLPTADLRNQIYDLMEGTTKLANS"
     gene            complement(7213..8847)
                     /locus_tag="RD451_002654"
     CDS             complement(7213..8847)
                     /locus_tag="RD451_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567857.1"
                     /translation="MRWYMNLKKIFSVKIFIVYAFVSLLYLFPAFKNMEIFGFYDTAF
                     HINRALSLESIFSSPINFETFRSYGMQVNNFYPWLTLYPLFLLIKFTNLAIGYNLFLY
                     IVTLITLFICHYVMYEITKKHVTSSFFAIIYTTSSFRSVEIFLRGAMGELLAMSILPL
                     ILLGFIKLYDSKKESWVMLAISMTLLIYTHVLSVAMTMVMIIIALIIQFYRKKKIEIF
                     LIIKLIKAAIVTLLLSLAFIGPMIEQTLYQDLNRPYVDILQKRAIYLGKEFLIGSIDS
                     ELLSFGIGLTLLICLIILTFNFKKLGILSKITYIMGIISILLCTKIFPWFALQNTPLN
                     IIQAPWRFMIFSTLFISFSVSLFISPQLEKFSYTRRRNFILLLILAISILNYSSVVNM
                     VKEMNFQGTYSNEQMENKLEEFENFDYVPIGYKKDQLLLKNHQVTEDGQVIYSSFSPN
                     KDEITFTLKSSKGKTIVLPVFRYKGLTVTVNSKNATVLKQGGPFVTVKSESGINKVTI
                     RYSYTFFSKISLFISIITLIVLLFYCIKLKIRTSHE"
BASE COUNT         2811 a         1693 c         1325 g         3028 t
ORIGIN      
        1 attttcaaaa gaaaaaagag aaggtgacaa aaattgtgtc accctctctt tttttattgt
       61 tttttaaagt gataggttgg ctcctccagg ttgggatcat aatcaacaag taaatcatat
      121 cctttaaaga accattcatc tgcttcctcg ataaaaaaaa gtgtcccatc aatttccact
      181 ttctttacag gatgttctgg ctgttcaact gacattccaa tcgaaaaacc atcatgaacc
      241 tctgttttgc cgtagacttt tccaaaaaaa cgtattccgt aagtttctgg cagatcaatt
      301 tctgagtcaa accacttttg tgcttttggc gttaccgtta atttcatccc aacaacctac
      361 tttctctttt ctttctattg attcatctta tcgtctagaa tatccacatc gcctgtctct
      421 ccaataacca gtagattatc attttcacga acatattcat ctgctgcagg agaagcgata
      481 accgtttgat ctactcttcg tatggcgact actgttaagt caaaacgttg cctgaaattt
      541 aattcagcta atgttttgtt gaaaaattta ggattggaga ctcggatttc tgctaaagaa
      601 tatttatctg acaactctag gtaatctaaa atattctttg acactaaatt atgcgcaatc
      661 cttattccca tgtctcgctc gggatggacg acgcgatcag ctccgatctt ttcaagtact
      721 ctggcatgat actcattttg ggcttttgct aaaatatttg gtacgcccat ttcctttacc
      781 atcagagtaa ctaagatact ggcttgaata tcttctccaa tagcgacaat tacatgatcg
      841 aaatttctta tgcctaatga tcgaagtgtc atttcatcct gtgcatttgc cacaacagca
      901 tgagtggcta tattcatata ttcattgacc cgatcttcat tactatcaat agccagtact
      961 tcttgaccag cttcgatcag tgttcggcag atacttccgc caaatcgtcc aagacctaca
     1021 attgcaaaat tttgtttcac cgttttcctc ctttagtatc ttcttttctc agtataacaa
     1081 agcctttaca aaaacaaaag caagcatcat tattgtaaaa aagccaagaa aaataatagt
     1141 tattttctca gcttttgatt atcctcttta tcatcgtttt tatttcacca aaccatgttt
     1201 gaatgcatag atagcggctt gtgtacggtc ttccacttct agcttagcca atatattgga
     1261 aacatgtgtt tttactgttt tcagtgtaat aaacaattcg tccgctattt cctgattact
     1321 ttttccttca gaaatcagca ttaaaatttc attttcccga ttcgttagtt cttcatgtaa
     1381 tacaggctca tttcgccgac tcattttttc catcattttt gttgtcactt ctggttctaa
     1441 tactcgctcg ccacgttgcg ttgcccttat agcatcagca atttcatgtg cggtagaggt
     1501 cttcaacaaa taccctgctg cacctgcttc aatggcagga taaacttttt cgtcatcaat
     1561 aaaactggtt acgataatga ttttagcttc tggccaatct tttaagattg cttttgttga
     1621 ttcgatacca tccatttctt ccatgactaa gtccattaaa atgacgtccg gtcgaagtgt
     1681 catcgccttc tcatagcctt gtcgtccatt ttcagcttct ccaattactt caatgtcttc
     1741 ttgaatagat aaataagaag agacgcctaa gcgcaccatt tcatggtcat ctactaataa
     1801 aacttttatc atccttatct atgcctcctt catcaaaggg accttgattt ctacacttgt
     1861 accttgacct ttaaaactaa tgatttttac tgttccacca ataccagcta ctcgttcttt
     1921 gatattgttc aatccataac ttcccgtttt cgtttcattc atattaaacc ctgttccgtc
     1981 gtcaataata cgtaacaaaa gattattgtc tattttgtgc aaatatacct ctaattcatt
     2041 ggctttagca tgtcttaatg tatttgataa caattcttga acgattcgga acaagtgatc
     2101 ctcaatggaa ctagatagtt ttacatcttc tacatcccat ttcagcgaaa tctggatttt
     2161 attttgcaat tccttcaata actgctcgat accttgcttt aaacttttct cttctaaatt
     2221 gactggacgt agatgaagaa gcagcgcacg catctcagac tgggaagcgt tgatgatctc
     2281 tgctaccatt ttcaactgct tgcgaaacat ttctggtgtc tcgctttttt ctgcttgctc
     2341 cgtcaatgcc gacatcatca tcattgctgc aaacaattgt tgcgaaactg aatcatgcag
     2401 ctcacgggct aatcgatgtc tttctaattc taaaatttct tctttggttt gtccatctac
     2461 atattgggga cggctcgtta caatttgtaa ttcactagat acttcaatca ttttttcttt
     2521 tatcttagtg atttccttat caatatcttt gatgtataaa tcgtccgatg cacttgggat
     2581 cggaagaagc aacaatttgg attcataatt gccagaagaa agtgcacgca gcttttcttc
     2641 gattttcccg tattttgtct tttgaataag tgataataat agaaagacaa ttaatcctac
     2701 acctaaggaa atggctaaca aatggaagat aagcggaaca tataataaac gtgcacgcag
     2761 taattctccc caccaatgac tttgattgct ggcataaaaa taagtgaaaa gtgaaaatag
     2821 aataataagg aaagccgcaa tccccgaata aacagctagc atcgctctgg atatttttcc
     2881 catcatattc gtatcacctc gacatctcca atcaaggtat tagtaataat cttcaatcta
     2941 cgagggtttt catcataatc actgctgtag attttgattt gttcattttt caaagaaaat
     3001 tgctcttctt caaacaagac atttcctact aatgtcgcat gctctaatcg gatggctacg
     3061 cccaaaggta ctaagatccg tgttctgcct atcccttttc ttacaatcac aatattatca
     3121 tcttttggca aaagcgtatt gcccaaatct atgatagtat caccagaaat gacggcgatg
     3181 ttgatatcgt cccattcata gacgtcgttt ccaatacgtt ggttaccgaa taattgctgt
     3241 cttttccgct cattattatg tgtttttaat tgctctgttt ggatcatcat gatctgtttc
     3301 tttcgccaaa aagcattttt ggttaaatct atccctgaaa tctctacatc tttcagacca
     3361 ataaataaaa cggcaaatac agccatcatc cataaagcag gactgttgac taagctaaaa
     3421 aaaatgacca aacttcctaa tatcaattga aaattttgaa atttagtacg aggatgtttg
     3481 cgcatagcta gatatatatt gaaaataccg aatatcacta aaagcaaaag tccagtattg
     3541 tttacgattt gccaaacagc aaataacagc agtagtgctt caactaccac aaaaaaacgc
     3601 caagaactat tcatcgctct ttctccctcc tgacacattc tcatttcatc atacctattt
     3661 ttttaactgt tggctatagg actttagatg taagatcgtt tgttgaaatc taaaatacac
     3721 aaagagaaaa agatctagag tgtatcatca gtaagatgaa ctctctagat ctttcagtca
     3781 gactacgctt gttctacttt gacgatttta actaacatat cgccacctgg agtagcaata
     3841 gttacttcat catttttacg tttgccaatc aatgcttgcg caataggaga atcattggaa
     3901 attttgccag aaaacggatc tgcttcagcg cttccgacaa tcgtgtactc ttcttcttct
     3961 ccatctggta gttcgatgaa tgtaactgtt ttaccaattg atacctcatc tgcatctaca
     4021 ccgtcgttat cgatgatttg agcaaaacga atcatatttt caattgttgt gattcttcct
     4081 tcaacaaatg cttgttcatc tttcgctgat tcatattcag agttttcgga aagatctccg
     4141 aaaccgcggg caattttgat tcgttcaatg atttctccgc gtttgactgt ttttagttct
     4201 tctaattctt tttctaattt ttctttacct tctagagtca ttggataaac tttctctacc
     4261 atgtgtaacg tctccttttt tcgataaaat accgcaaaag gtaatctttt gaggaatata
     4321 gtccaaaaaa gattaccacg cttttcttca aatgtaaatg tttttctaaa aatgatcaat
     4381 gtctagagcc tgtttttcta agaattattt acatattttt ccactaattc catatgttct
     4441 tcataagttt tagcgaaata aacatttcca gtgctcgtat ctgctacgaa ataataatag
     4501 tcattttctg ctggttctaa tactgccttg attgcctctt cgcttggatt gtcaaaaggt
     4561 ccaggtccat agccggtatt ggtatacaaa ttatatggtg aatctacagc tgtatcttca
     4621 tacgtcacta attctttgtg ttcacctaat gcgtataaaa cagagatatc tgactgaagt
     4681 ggcatatttg ctttgattcg gttaaagaag acttgtgcaa tgtttttacg atcattttct
     4741 tttacgcctt ctttttcaac tagagaagct agagttaaaa cttcttgtac agtcaaattt
     4801 ttctgcttga tagctgaata atagttttgc atgaccgtat tcgtcttgtt caccatttca
     4861 atcactagat ccttaagcga agtactcgtg taataatcat atgtggctgg gaataagtaa
     4921 ccttccaaac ggtattttgt gttctcagct ttagatgcac tttccaacag ttctgggaat
     4981 ttttggtgca actcgttaaa gaaagtctca tcattcacta aatctaaaaa ttctttcttg
     5041 tctttaccag ttaccttcgc tacccgttca gcaatctgat cgatatcgta cccttctgga
     5101 atggcaattt tcccatctgc aacttttgtt ggctcagaag taccgccttc ttgcaactgt
     5161 ttgccaatct cgtcaagagt catattaggc gctaactgat aatagccagc ttgaaagcca
     5221 gttaaatttt taaattttgt ataataattg aaaacaatcc cgcttttaat aatattgtcc
     5281 ttctccaaaa tctcaccaat ctgcttgtta gaagagccac tcgggatctc gacttggact
     5341 aattggtcat ctgatttatc taaaggcttc aacccgctat ctacataacg atacacggta
     5401 aatccaagaa atccgccaat aatcaataat gtaagagcaa tcactaaaat gatcttcctc
     5461 acaatcttat cttctttttt acgcagattt ctccgcttgt cgattatatc tgctgtagct
     5521 gccttactgg cttctttttt atctttactt gggtgttgtt tgtttcctga caaaacaact
     5581 cctccttact atcaagttcg taactttatt cattatacat gatatttgaa ttggcgtgaa
     5641 tgattttatt taaatattct atcaaaaatg taagtagtaa atccattact ataagattaa
     5701 aataaatgtt atcaagatac aagctatttt agctttattc tttctgtaaa aaagaaagga
     5761 gactaaataa actattatga aaaaaggaaa acatgctaaa aaaagaaaat attcattttt
     5821 aatgatcgtt gtcgtgttgt ttagccttag tgcgttctct acaggaacta ttcttggatg
     5881 gcaattttac aataatgaac actctcagat agttgcccat gctcaatcag ctcaaaaaaa
     5941 gttgatactg actaccaatg aacaacagct cgttgaaaaa atcgatcaac tattaagaaa
     6001 aaatgattat attggctcaa tttacgtaaa gaaaaataat cgcatcatca tggaaaaagg
     6061 ctatggctat gcgaataaac tcacgcaaca accaaatgat ccttctcttt attatcagat
     6121 tggttcggtt caaaaagcat tgactactct tttgatttta aaacaagtcg agcgtgggca
     6181 cctttcttta gatactaagc tggctcaatt ctatccacaa attgctggca gccagcaaat
     6241 tactatccgt gacttgctgt atatgcgctc aggcttgcac cgaactgctt ctccaaccat
     6301 accgatgact gatgaagaag tcgttcaatt tgcgattcag cacttaaaat ttacagatta
     6361 tcagacctct cattatgatt cattgaactt taccatattg actggaattt tgatcaaatt
     6421 aacaaatcaa ccgtatgaaa aattattgac cgatgatatc atcgaacctt taggattaca
     6481 gcatacaaaa ttttatgacc aagtcaaaaa ttcatccaat catgcactat cctatcaaat
     6541 gtctaaagag gatgattact ttaaaccact gacagaatct gaaacagaga tccataacga
     6601 attagggact ggtaatatca gtatgtccgt ctatgattta aatacgctgt ttacacaagt
     6661 tttatctgga aaactagttt ccaaagactt actcttctca ttatggcgtg aaaatgcgaa
     6721 tggacatcca tatagtggtg gggtatatag cggagataat tatatcctgt cgcaaggaaa
     6781 tatcgactct tttgatacat ctgctatatt tagcaaagat tcacaggatg ctatcatcat
     6841 ggaaagcaat ataaaagctg acaaaactat caaactgcct actgctgatc taagaaacca
     6901 aatctatgac ctgatggaag gaactactaa gttggcaaat agctgatatg atgaaaagat
     6961 agcaaatact acttctttga atagcatttg cttaaaaaaa gtactcgact aaacgtagga
     7021 aagagtgtgg gacaaatcta aaaatcaatt tttgctacag actttaattc caaataaaca
     7081 gaacagaaag aggtgttctt ctttctgttc tgtccaaatt attctaagat ttctctttac
     7141 caacattatt tgacaaaggg cctattaaat ctaaaatagt atctttagat tgctaaaata
     7201 tgtgctagca aatcattcat ggcttgttct tatttttaat tttatgcaat aaaaaagaag
     7261 aacaattagc gtgattatag aaataaataa tgagatttta gaaaaaaatg tgtatgaata
     7321 cctgattgtt actttattta ttccactttc actttttact gtaacaaaag gacctccttg
     7381 ttttagtact gtagcatttt ttgaattaac agtaaccgtt aatcctttat accggaatac
     7441 aggtaaaact attgttttgc cttttgaaga tttaagcgta aatgtaattt catctttatt
     7501 tggagaaaag ctactataaa taacttgacc atcttctgta acttgatggt ttttcaaaag
     7561 caattgatct tttttatagc ctataggtac ataatcaaaa ttctcaaatt cttcaagttt
     7621 attttccatt tgttcattag aataagttcc ttgaaaattc atttctttca ccatgttaac
     7681 tactgatgaa taatttaaaa ttgaaatagc taatattaat aatagtataa aatttcttct
     7741 ccttgtataa gaaaattttt ccaactgtgg agaaataaat agagatactg aaaaagatat
     7801 gaacaatgtt gaaaatatca taaaacgcca aggagcttga ataatattta aaggagtatt
     7861 ttgtaaggca aaccatggaa atatttttgt acaaagtaga atagatatta tacccattat
     7921 ataagtgatt ttagataaga ttcctaattt tttaaagtta aatgttagta taattaaaca
     7981 aataagcaaa gttaagccaa taccaaatga tagtaattct gaatctatac ttccaatcaa
     8041 aaactcttta cccagataaa ttgctctttt ttgtaatata tccacataag gtctattcag
     8101 atcttgatac aatgtctgct caatcatagg acctataaac gctagtgaaa gaagtaaagt
     8161 aactatagca gcttttatta atttaataat taagaagatt tctattttct ttttccgata
     8221 aaattgaata attaaagcaa ttataatcat taccatagtc atagctacag aaagaacatg
     8281 agtgtaaatt aataaagtca tgctaatcgc caacataacc caagattctt tttttgagtc
     8341 gtaaagcttt ataaacccga gtaaaataag aggaagtatt gacattgcga gtaattcccc
     8401 cattgcccct cgaagaaata tttctacact cctaaaagaa gatgttgtat atataatagc
     8461 gaaaaaggag ctagtaacat gttttttggt aatttcatac attacataat gacatataaa
     8521 tagagtaatg agcgtaacaa tataaagaaa aaggttatag cctattgcta aattagtaaa
     8581 cttgatcaat aaaaataaag gatatagagt taaccatggg taaaaattat ttacttgcat
     8641 gccatatgat ctaaacgttt caaaattaat aggggagcta aaaatagatt ctaaacttaa
     8701 cgcacgatta atgtgaaatg ccgtatcata aaagccaaat atttccatgt ttttaaatgc
     8761 tggaaataaa tataataaac taacaaatgc ataaactata aatattttta cagaaaaaat
     8821 ttttttcaaa ttcatatacc acctcatgtt tttttat
//
LOCUS       DAPBAF010000079         8645 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.082, whole genome shotgun sequence.
ACCESSION   DAPBAF010000079 DAPBAF010000000
VERSION     DAPBAF010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8645)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8645)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8645
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.082"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            <1..135
                     /locus_tag="RD451_002655"
     CDS             <1..135
                     /locus_tag="RD451_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HDT7567858.1"
                     /translation="FNQVNQGFISSVASKRNHIPRKSLNYQTPLEVFLSYVNGKFCLA
                     "
     gene            complement(88..324)
                     /locus_tag="RD451_002656"
     CDS             complement(88..324)
                     /locus_tag="RD451_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006735101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7567859.1"
                     /translation="MATKIADELENHVLETGMQKITTHASITAKPFFEKRGYKVINEQ
                     TVELRGQLFTNFLMILFVKLSETKLSIYVTQKNF"
     gene            complement(744..1865)
                     /locus_tag="RD451_002657"
     CDS             complement(744..1865)
                     /locus_tag="RD451_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
                     /protein_id="HDT7567860.1"
                     /translation="MDKYNVKTSFQKWFSAINFSGLSENSQSLISDFDFYSKKLDFQT
                     TLKVLLHAVYEELPSYREIDRAFLDQRLCKELGIDSLCYSSLSRRAPEIKQEVLMEIF
                     TQLVARISAQQPSSKTTSLQLIDSTTIPLNKAWFPWAKFRKTKSGIKLHLNLCYLDKT
                     NQYPESFTMTNASEHDRNHLEVLVDKTQATYVMDRGYFDYKLLDKLNRDGYFFVTRTK
                     SNTKITILDQIEVADTTTRDGTIISDQQVILVGGVNHVTERFRLVTVLTKGQKILRMV
                     TNLFDVSPNEVADMYQARWQIELLFKHLKQNLTIKRLYSHSEQGAINQVILTLIATLL
                     TYVIKIELNTTATLFQLKRTFHYLMFEPAEEWFKRYKPG"
     gene            2193..3602
                     /gene="istA"
                     /locus_tag="RD451_002658"
     CDS             2193..3602
                     /gene="istA"
                     /locus_tag="RD451_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HDT7567861.1"
                     /translation="MDDIKTIKHLRNNRDQSIDQIRKAMNINWRTAKKYADSDQLFIT
                     DPTRKNKSMMDDGWGEIIGSWLEEDLRLRRKLRRTAKAIHEQLKPLGFPGSYRTVCVY
                     ISQWKKQRYDETNYQAVDRLDHPIGEAQVDFGTMEVMHEDHMKDIQLLIMSFPYSNAT
                     SASAMPAQNQECFLEALKQLFNQCGGVPKTIRIDNLTPAVKKTKSKFEEAQLTDEFLR
                     FTIHYGCDVQVCNPRSGHEKGHVENKVGYVRYNFFSTSPIMDSFESLNKQLEEQLKAD
                     RKRTHYSKHQLIEDLWKKENKALHSLPQEDYPIFKEVEAKLNRYHEMKLDQTVIHIPK
                     AYGYSQLTVVLTWNKFKVLTPHGEILMNEYRPYMNKKRLIPWSDIMKQWSNKLNVVSY
                     SRYWKYLPARLQNYLAIDNNHLKYRRIKQLLSLLATYDIQQINEQFYELVVQEDAPSD
                     FDVNWSNYDALTKTGGVQK"
     gene            3599..4327
                     /gene="istB"
                     /locus_tag="RD451_002659"
     CDS             3599..4327
                     /gene="istB"
                     /locus_tag="RD451_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element helper ATPase IstB"
                     /protein_id="HDT7567862.1"
                     /translation="MIGQTLEDYCKKLRLSHIITNIPRASFEAPEQFITDLFRLELET
                     RQQIKLERMEKLAKFPVPKSLKNYEWHEDIFLPSHLDKETLVSLDFLKRQENIVCVGS
                     PGTGKTHLAIALGRKACSEGVSTKFFRVNNLVEQLENALKKQQLASFKKRFETTELII
                     LDEMGYLPLTKEGAELLFQLISDWYEQKSIIITSNLEFSQWNRVFMDSRLTAALVDRL
                     IHHAHIISFKGESFRLKNSLSKSY"
     gene            complement(4455..5366)
                     /locus_tag="RD451_002660"
     CDS             complement(4455..5366)
                     /locus_tag="RD451_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDT7567863.1"
                     /translation="MKIKIERSNKEKIPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GIYKNFTAIDQHTTHEKVVVKEKIVNTSGVENFTVDFVKEYFSWKNNKEVIEKRMTNL
                     EQYLTEEGFALSQDMVRADIPTSSEVVSVKILDVEKHSEEFVVSFVVDQKITEGKKTQ
                     SISSAYRLMIFEDEKGNHIVTSLPTMIGKPEKAKHKVRQVKSDSKIDSKTTEEITEFL
                     ETFFRLYPAASEKELEHYVEKDAMQPINTNLKFVELVNPIYKQKGKAIQVIVGVEYLD
                     ELSKTTSVFQYRLKLYKNENWTISNCE"
     gene            complement(5383..6390)
                     /locus_tag="RD451_002661"
     CDS             complement(5383..6390)
                     /locus_tag="RD451_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDT7567864.1"
                     /translation="MNLKKLSIISLTFLTISFVGILMCVGLLFGEDGEGSGSSGTSPG
                     GSSVSEVVLKHRSMVEKYAKESDITEYVSILLAIIQVESGGTMEDVMQSSESAGLSPN
                     SLSTEASIKQVCLYFSSLVKCSKELGCDQDSIIQAYNYGDGYLDYVAKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENSGWRYNYGNMFYCLLVKQYLTTTQFDDKTVQGIF
                     DEAFKYEGTAYVFGGSSPGTGFDCSGLTQWCYAKVGLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLIFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTDSYWQQHIIGAGRYK
                     Q"
     gene            complement(6387..8516)
                     /locus_tag="RD451_002662"
     CDS             complement(6387..8516)
                     /locus_tag="RD451_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HDT7567865.1"
                     /translation="MKKKLFRIVGIVFISIVLLTVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAKSIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRTVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALSLGTKIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEGRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKRAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRTFAFGGGAAVGGKLATSSTKGKGSSKINRVSNRKNHSARSINELNSDLKK
                     QEQPVGTKKESRINLVGRKVGKVLDTKEIVKDKAKQAKNQVTDAPTNLKYSLHKGMEK
                     TKKVPEDFKRGPFEEKANRGELREKQRQRRDAKMDEKRKVLNEAWNRHEKGRENVPIK
                     KEIKPQKNELPENRSLKPRVQVHSNPEIKRKLSSQEVIPNGSTQPLSKNNSFQQVKQR
                     FTFPKRTNQQVQRKKNTRPKPKPGEKR"
     gene            complement(8521..>8645)
                     /locus_tag="RD451_002663"
     CDS             complement(8521..>8645)
                     /locus_tag="RD451_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDT7567866.1"
                     /translation="NGQCLMQDLYGRVGVVQVHPVFEELFHAFDTRPPVQERME"
BASE COUNT         2656 a         1757 c         1503 g         2729 t
ORIGIN      
        1 ttcaaccaag tcaatcaagg attcatctca tccgttgcgt ccaaaagaaa ccatatccct
       61 agaaaatcac taaattacca aacaccatta gaagtttttt tgagttacgt aaatggaaag
      121 ttttgtctcg cttaatttga caaataatat cattaaaaag ttagtaaata attgccctct
      181 aagttccacg gtctgttcat taataacttt atatcctcgt ttttcaaaaa atggctttgc
      241 ggtaatggaa gcgtgggtag tgattttttg cataccagtt tctaaaacat ggttttccaa
      301 ttcatctgca attttagtcg caataccttt tccttgatgg ctatgttttt gtcacaactt
      361 cagtattcct gtaacaatac ggatttcagt atacaacaac agcttttgaa aagatacttg
      421 caaaaggatt aagatatcta tgacctgcta tgctcactga tgttgaaaag aatgttttat
      481 taggattgag gtaagcaaga tagtgaatat gtccggaaag cctgtaaaat aaggcttttc
      541 ggacatatgt gaagttataa aaagatagcg aaaaatctat ttagtatcac taatgttgcg
      601 aacatatcgt cagaatagtc tgacatttat ttcttgctaa aaatttcaaa aaagtcaagt
      661 gctgacgcag cggatgacta ttttccagaa aattttagta tgtattcaaa aatcaaacgt
      721 gacaacagct attaactaca tcctcatcca ggtttgtaac gtttgaacca ctcttctgcg
      781 ggctcaaaca ttaagtaatg gaaggtacgt ttcaattgaa acagcgtcgc tgtcgtattc
      841 aactcaattt ttatcacata agtgagaagc gttgcgatta aggtgaggat gacttgattt
      901 atcgcccctt gttcactatg tgaatatagt cgtttaatgg tcagattttg ttttaagtgt
      961 ttgaacaaca attcaatctg ccaacgggct tgatacatgt cggccacttc gtttggcgat
     1021 acatcaaaga gattggtcac cattcgcagg attttttgtc ccttggtaag aaccgttacc
     1081 aacctaaaac gctctgtcac atggttgaca ccgccgacaa gaatcacttg ttggtcactg
     1141 attatcgtcc catcacgggt tgttgtatct gctacttcaa tttgatccaa gatggtaatt
     1201 tttgtattag attttgtccg tgtaacgaag aaatagccgt cacgatttag tttgtctaac
     1261 aacttgtaat caaagtagcc gcgatccatc acatacgttg cttgcgtttt atcaacaaga
     1321 acttcaaggt gattacggtc atgctcactc gcatttgtca tcgtaaaact ttcaggatac
     1381 tgattggttt tatcaagata acagagattc aaatgtagct tgatgccaga ctttgttttc
     1441 cgaaacttgg cccatggaaa ccatgctttg ttcaacggaa tagtcgttga atcaatcaat
     1501 tgtagactgg ttgtttttga gcttggctgc tgagcagaaa ttctggcgac taattgcgta
     1561 aaaatttcca tcaatacttc ttgcttgatt tctggcgctc tacgagataa cgagctgtaa
     1621 cacagggaat caatgccaag ttccttgcag aggcgctgat ctaaaaaggc gcgatcaatc
     1681 tcgcgatagc ttggcaattc ttcataaacc gcatgaagta acactttaag cgtcgtttgg
     1741 aagtctagtt ttttactgta gaaatcaaag tcgctaatta agctttgaga gttttctgat
     1801 aaaccagaaa aatttattgc agaaaaccat ttttgaaatg aggtttttac gttatactta
     1861 tccatgcgtg agtccttttt attggtcttg gataagtcat ccgagaatag tataaaggac
     1921 ttttttgcgt ttggatagct ttgtattagg cttttgatgg gttaaaaagt ctttgcaaca
     1981 ctagtaattt agtatttatg tataaattga aagatatttt accaccactt agtcttctta
     2041 aaagtgatcc aacattttgt ttgtggcaga atttaactac acactaatgc agccgaaagt
     2101 acacaactat gcagcagttt gactgcgaac tggtttcctt ccatcataag tttgaatgac
     2161 ttagtgatgg aggtacagaa aggttgttaa ctttggatga tattaaaaca ataaaacatt
     2221 tgagaaataa tcgtgatcag tcaattgatc agataagaaa agcaatgaat atcaattggc
     2281 gaacagcgaa aaaatacgcc gatagtgatc aactattcat tacagatccc actcgaaaaa
     2341 acaaatccat gatggatgat ggttggggag aaatcatcgg tagttggcta gaagaagacc
     2401 tacgtttacg cagaaaactt cgtagaacgg ccaaagctat ccatgaacaa ttgaaacctt
     2461 tgggtttccc tggctcctat cgaacagttt gtgtatacat ttctcaatgg aaaaagcagc
     2521 gttacgacga aacgaattac caagctgtcg atcgtcttga tcatccgatc ggagaagcac
     2581 aggtcgattt tggaacaatg gaagttatgc atgaagatca catgaaagat atacaacttc
     2641 ttatcatgtc atttccctat agtaatgcga cgtccgcaag tgccatgcca gctcaaaacc
     2701 aagagtgttt cctggaagca ttaaaacaac tatttaatca atgcggcggc gttccaaaaa
     2761 cgatcagaat agataactta actccagcgg tgaaaaaaac aaaatcaaaa tttgaagaag
     2821 cacaactaac cgatgaattc ttacgtttca ccattcatta tggttgtgat gttcaagtct
     2881 gtaacccacg tagtgggcat gaaaaaggac atgtcgaaaa taaagtgggt tatgtccgat
     2941 acaatttctt ctcgacttcg ccaatcatgg actcttttga gtccctaaat aagcaacttg
     3001 aagaacaatt aaaagcagat cgaaaaagga cgcattattc aaaacatcaa ttaatcgaag
     3061 atttgtggaa gaaagaaaat aaagcgttac attctcttcc acaagaggat tacccaattt
     3121 ttaaagaagt ggaagctaaa ctaaatcgtt atcacgaaat gaaattggat caaacggtta
     3181 ttcatattcc taaagcatat ggctattctc aattgactgt tgttttgact tggaataaat
     3241 tcaaagttct tacgcctcat ggagaaatat taatgaacga atatcgcccc tatatgaaca
     3301 aaaaaagatt gatcccatgg agtgacatca tgaaacaatg gagtaataaa ttgaatgtcg
     3361 ttagttattc gaggtattgg aagtacttgc ctgcacgcct tcaaaattat ctagcgattg
     3421 ataataatca cctgaaatac agacggataa aacaattact aagtttatta gcgacctacg
     3481 atatccaaca aattaatgaa caattttacg aattagtcgt tcaagaagac gccccctctg
     3541 actttgatgt gaattggtca aactatgatg cattaacaaa aacaggaggt gtgcaaaaat
     3601 gattggacag acgttagaag attattgtaa aaagcttcga ttaagccata tcatcacgaa
     3661 cataccaaga gcttctttcg aagctccaga acaatttatt accgatttat tccgtttaga
     3721 actggagacc agacagcaga tcaaattaga acggatggaa aaattagcca aatttcctgt
     3781 accaaaatcg ctaaagaact atgaatggca cgaagatatt tttctaccat ctcatctaga
     3841 taaggagacc cttgtctctc ttgattttct aaaaaggcaa gaaaacattg tttgtgttgg
     3901 ctctcctggt acagggaaaa cacatctagc gatcgcatta gggagaaaag cctgtagtga
     3961 aggtgtttca accaaatttt tccgagttaa caatctcgta gagcaattag agaatgcatt
     4021 aaaaaaacaa cagctagcca gtttcaagaa gcgattcgaa acaacagaat taattattct
     4081 tgatgaaatg gggtacttac cattgacaaa agaaggagct gaacttctct tccaactgat
     4141 ttcagattgg tatgagcaaa agagcattat tattacctct aatttagaat tcagtcaatg
     4201 gaatcgagtg tttatggatt ctcgattaac agctgctctc gttgatcggc taatccatca
     4261 cgctcacatt atcagcttca aaggcgaaag tttcagattg aaaaattcat tatctaaatc
     4321 atattgaagg aaaaaactag ttgcagcaaa actctgcact ttcggctgca tttttttgta
     4381 aaaagctatt gcacaacaca aacatttgaa cgacgtaatt ccaaatgttg gattgctttt
     4441 agataatctt ttatttattc acaattgcta atagtccaat tttcattttt gtatagtttt
     4501 aatctatact gaaaaacact tgttgttttg gacaactcat caagatactc aacaccaaca
     4561 atcacttgaa tcgctttacc cttttgtttg taaataggat tcactaattc cacaaatttc
     4621 aaattagtat taattggttg catcgcgtct ttttcaacat aatgctctag ttctttttct
     4681 gaggctgctg gataaagcct gaaaaacgtc tctaaaaact cggtgatttc ttccgttgtc
     4741 tttgaatcaa tttttgaatc actttttact tgtcttactt tatgttttgc cttttctggc
     4801 ttaccaatca tagtgggtaa actcgttaca atatgattgc ctttttcatc ttcaaagatc
     4861 atcagacgat atgcagaaga aattgattgt gtctttttcc cttctgtaat cttttgatct
     4921 accacaaatg aaacgacaaa ttcttccgag tgtttttcaa catctagaat ttttactgat
     4981 acaacctcgg aactagtggg aatatccgct cgaaccatat cttggctcaa agcgaaccct
     5041 tcttctgtaa ggtactgctc aagattagtc attctctttt caattacctc cttgttattc
     5101 ttccatgaaa aatattcttt cacaaaatct acagtaaaat tttctactcc agaggtattc
     5161 actattttct ctttcacgac cactttctca tgagttgtat gctgatcaat ggccgtgaag
     5221 tttttgtaga ttccaaaagc aaggctacaa gacaataaaa gccaaagggc aagcaccatt
     5281 tttcgatgct tgcccacgga tactactcgt tctttcttct tttttggaat cttttccttg
     5341 ttacttcgct caatttttat cttcattttc cattcctctt ttctattgtt tataccgacc
     5401 agcaccaata atgtgctgtt gccaatagct atcggtaaga ttggtccaac ccaccggatc
     5461 tcctgcatga aacattctgt tctctcctgc ataaatgccc acatgagtca cataagtacc
     5521 ggcatcataa gttgaatgaa agaaaatcaa atcgcctggt ttggcatctt ttaagtcaat
     5581 atgagtcata gcatcatatt gatcctgagc cacccgaggg agtttcaaac caactttggc
     5641 ataacaccat tgagttaaac cactacaatc aaacccagtt ccgggacttg acccaccaaa
     5701 tacataagcc gttccttcat acttgaacgc ctcgtcaaaa attccttgga ctgttttatc
     5761 atcaaactgt gttgtagtta ggtactgctt cactaataag caataaaaca tattgccata
     5821 gttataccgc cacccactat tttccttaat cgcgatggga ttgggataat cgactttttg
     5881 accacccgat ttttcttttg aaaaagattc ggctaaagca aaactatgct tctttccgtt
     5941 tttcgcgaca taatccaaat acccgtcacc atagttataa gcctgaatga tactatcttg
     6001 atcgcatcct agttctttgg aacacttaac caaagacgaa aaatagagac acacttgttt
     6061 gatggatgcc tcggtactta atgaattcgg tgataaacct gctgattcag aactttgcat
     6121 gacatcttcc attgtacctc cagattcgac ttgaataatc gccaaaagaa tcgaaacata
     6181 ctctgttata tctgattctt tggcatactt ttccaccatt gaacggtgtt tcaaaactac
     6241 ttctgagaca ctactacctc caggagaagt tccagaacta ccacttccct caccgtcctc
     6301 accaaacaac aaacccacac acatcaagat gcccacaaaa gagatggtca ggaaggttaa
     6361 cgaaataata ctcaattttt ttaagttcat cttttctcac ctggctttgg ttttgggcga
     6421 gtgttctttt ttctttgtac ttgttgattg gttcgctttg gaaaagtgaa tctctgtttc
     6481 acttgttgaa aggaattgtt cttgcttagt ggctgagtgc ttccgtttgg aatgacttct
     6541 tgactagaaa gtttccgttt gatttcagga ttcgaatgta cttgtaccct tggttttaaa
     6601 gacctatttt ctggtagttc atttttctgt ggttttatct ccttttttat cggaacattt
     6661 tcccttcctt tctcatgacg attccatgct tcgttcaata ctttgcgttt ttcatccatt
     6721 tttgcgtctc ttcgttgtcg ttgtttttct cgcaactccc ctcgatttgc tttttcttcg
     6781 aaaggccctc gcttaaagtc ctctggtact tttttcgtct tttccatgcc tttatgaagg
     6841 ctgtatttca agttagttgg tgcatcggtt acttgatttt ttgcttgttt cgctttgtcc
     6901 ttcacgattt cttttgtatc gagtactttt ccaacttttc taccaactaa atttattcgt
     6961 gattctttct tcgtgcccac tggttgttct tgttttttca gatcagaatt tagctcgtta
     7021 atgcttctcg cggaatggtt ctttctattg gacactctat tgatttttga actacctttc
     7081 ccttttgtag aactggtagc tagtttccca ccaactgctg caccgccacc aaaagcaaaa
     7141 gttcgaccca catttcgatt aagctgtcgc aattttcgat tcatcaacat ttgcggtttc
     7201 cgcatgactc gccttcccat tgactgacta tcattacttt gaaggttaaa catgctcata
     7261 atgtcaccta atttgaaata gataccggca aaggtcacaa tttgtagaaa agctaccata
     7321 aagaagggat aggtggccga aatattgaaa aacatcgtgg agatactgaa tgcagtcgta
     7381 atgactaagg taactcccgc tcgcatcata atcgtattga acaaacgaat aatcgccctt
     7441 ttgcccaaac tctcatacgt cggcaacatc gacaataaga aactaatggg cagaaacatc
     7501 gcaaagataa tgaaaaggat ttgtgagaac aacataatcc ctgtcagaag aaacacaaaa
     7561 aaggaaatcc caatattaaa caacactaaa aagaccacgg ttcctaaacg gttcatggtc
     7621 ttggtaatac tgagattcgc attgtcatta tcttcaatct ctgctttgac tgcttcttcc
     7681 cgatccttac ccttattttc atccggactc acggataaaa tcttattaac ccgaccctcg
     7741 ccaatttctt ctatattgga atcatcgaat tgtaatagta accagggttg ttgaacttga
     7801 atcgaaaata aactgtctcg aatcaaatcc acactatctt ttccctggct ttctgaatta
     7861 ggtacaacaa tcttggttcc aaggctaaga gccgcttcac taacgtctga gctaaagtca
     7921 ttgatttttg taatataggt gggcgcatac gcaatgaaag aacccgagag tagaaaaatc
     7981 atcacaaaat taatgacggt tcggactgct ttggtagttt ctcgttttaa taatccggta
     8041 tacgccacat aaactcctag agctaaaatc atcaataata ggaacccaaa gtagaatccc
     8101 gaagtctgta atccattttc agtgataccg gctaaagttt ggatattctt tccaatactt
     8161 ttagccgtat ccgaaatgaa atccaacttg taagcttctt gaaccacata gcccgtggcg
     8221 tttgataaat acagacttac tgtccaaata aaattggtaa tggcataaag accatacatc
     8281 acgcttttcc ctaagccatc cccccaattc caaggtaacc aatcccaaga actatccaca
     8341 aagaaatcca gttgataatt gttcagagaa tatttggaat aaaggtttcc ggcttcaact
     8401 gtatcatcaa ccagacctgt cgcctcagct accgtaccga ctaaactcaa tagaactgtc
     8461 aataggacga tgctaataaa aacgattccc acaatccgaa aaagtttctt tttcatcccc
     8521 tcactccatt ctctcttgaa ccggcggacg agtgtcaaaa gcatggaaga gttcttcaaa
     8581 gactggatga acttgaacca cacctactcg cccatacaag tcttgcatca agcattgacc
     8641 gtttt
//
LOCUS       DAPBAF010000080         8104 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.083, whole genome shotgun sequence.
ACCESSION   DAPBAF010000080 DAPBAF010000000
VERSION     DAPBAF010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8104)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8104)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8104
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.083"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(21..668)
                     /locus_tag="RD451_002664"
     CDS             complement(21..668)
                     /locus_tag="RD451_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HDT7567867.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(676..1362)
                     /locus_tag="RD451_002665"
     CDS             complement(676..1362)
                     /locus_tag="RD451_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7567868.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(1368..2441)
                     /locus_tag="RD451_002666"
     CDS             complement(1368..2441)
                     /locus_tag="RD451_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7567869.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            2663..3337
                     /locus_tag="RD451_002667"
     CDS             2663..3337
                     /locus_tag="RD451_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7567870.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            3342..4682
                     /locus_tag="RD451_002668"
     CDS             3342..4682
                     /locus_tag="RD451_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDT7567871.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(4831..5817)
                     /locus_tag="RD451_002669"
     CDS             complement(4831..5817)
                     /locus_tag="RD451_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HDT7567872.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
     gene            6541..7572
                     /locus_tag="RD451_002670"
     CDS             6541..7572
                     /locus_tag="RD451_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDT7567873.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
     gene            7681..>8104
                     /locus_tag="RD451_002671"
     CDS             7681..>8104
                     /locus_tag="RD451_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HDT7567874.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQI"
BASE COUNT         2569 a         1492 c         1391 g         2652 t
ORIGIN      
        1 atacacatag ctgtttcttt ttattgtatt ccttcagcaa tccaacgaga tttatagcga
       61 aagtctttta acaactcttc ttttgtccaa ttatttgcaa tgagatccgt caaagtgttc
      121 attacgaggg tcatggaaaa gtataggaaa ctaactgctt cttccgacga ttgaatggag
      181 aaatgattga ttcttaataa ttccagccat ttttcgttca ttggagaatc agccgatagt
      241 tctctacgtt tggttgtctg ctgatcattt cgctgggtta acaagtataa cctttgccaa
      301 tagatacttt cgtgatctaa gtcgcagcac cactctaaat atttttcgat ccccaaaaag
      361 aaatgttgtt tgttttcgct aatgaatttt aagatatctt gatggactat gtgagaactg
      421 cttttgatcg tatacaaata agcatcttcc aaatcttgaa aatatttata aaaagcaccg
      481 cgcgacatcc ccatcttgtc aacgatttct gagactttga cttggctgat gtgctgtgag
      541 caaaatatct ccagtaatag gtcatcgatt ctctgtttct ttgcgttcga taaattgaaa
      601 aaagtttctt ttggcatcca catctctcct ttatctctga ttatacgtgg atagcccttc
      661 attgtcatga aggattcatt ccttcttttt ctcttcttct gtcaagtacc catcttccat
      721 tcgataaacg cgatcactcc attgaatcat acggacatca tgagtaacca taatagtcgc
      781 tttttgtttc tcatgagctt ctttaactag taatttgacg acttcatatg catgatctgt
      841 atccaaacta gctgttggtt cgtctgctaa gatcaagctt ggctcattat ataaagcgcg
      901 agcaattgcc actctctgtc tttctccacc agaaaggtct ttaggataac tatttttaag
      961 tgactggata tctaaagatt gcagcaagga atcgattttt gttgaatctt ctttttttga
     1021 agtaacttgg tcaactagtt caaattgttc ctttaccgtt aaaaaaggaa tcaaattaga
     1081 gctttggaga ataaatccta tttctttaaa gcgtaaatct gctcgttttt tttctggaag
     1141 ctcagttagt gagtgaccgt tgatcactat ttctccggaa gtcggtgttt gcaatcctcc
     1201 tgaaatggta aggaaagtac ttttacctga accagaagga ccaatgatgc tgacgaattc
     1261 tccttccttt acataaaaat caattgcttt caaagctgag acctttgtat gaccagaacc
     1321 aaatgttttg gtaacttttt tcatcgttaa tatttttttc atttttatta acctcctatt
     1381 gctgtaattg ggtctacttt ggttatcgta cgtatcgaaa acaatccgcc tagcattgcg
     1441 acaatgatca aaatcccact atatagcaac cattgtgacc aaaaaacagc aaaaggcatc
     1501 gcgcttggta aaatcagact agtcaaataa gcaaacaaaa gagcaagcag aacgcctacc
     1561 accccaacaa taaaggactg tgctactaaa gatttagcga tgaagaaatt tttgatccct
     1621 tgtgctttca ttactccaaa aatagcagtc ttctgaagtg tcatcacgta catgaaaata
     1681 ccgaccacgg cagcaaccac taagaacaaa aagtatatca tcgcatttaa ggtcatattt
     1741 tgggcagaat agccaggaat actttcaatg aatgtcccaa tagttaataa ctgtagaccc
     1801 ttcgatgctt tttctttcga aattttagct gaatccttta ttacgatccc attgatcggc
     1861 tgttcttctt cagaagcaaa cggctgttgt ccatacttca aagcagtcca cgtatctagg
     1921 gacgcataga tgacgggaga aactgtgtaa taagtttcag gaaagatacc gacaatcgtc
     1981 aaaggatcgt cgtaactgcc aattttgatc gtatctccaa ttttatagcc tgaatcagcc
     2041 agattttgag agatgatgat ttcattcttt gttttaaatt catgcccttt cgtgagtttt
     2101 ggtaataaaa atgcttcttt cgttgtgccg aaaactgtaa cattttcttt gttttttcct
     2161 ttgattgctc cgctgtacaa tccgattggt gctttctctc ctccttcaat gtatttcaga
     2221 tctcctcttg ttaattgtga agctgcaaat acttgatttg catcctccga caaaacaatc
     2281 tcttgtgcgt cccaatcatc gattgctttt ttaaactctt ctgaaagtcc attcgctagt
     2341 cctgacaaca tgaatacgac atacgcaatc aagaacataa taccgacgat caagccatat
     2401 cgtaatttag aatagcgaat ttctttgata gctagaaaca tttgtttttc ctccctatga
     2461 tagattgata gtgacaaaat gtcacttgtt gaatagtgta actctaaagt gacaatttgt
     2521 cacttgtgtt gtttttttct tatcaataaa ttgtctaaga catctttcga taaaacctta
     2581 acatgagtca taaaaaattt atttaagcct tatttatgct ttccatgata aactaaagtg
     2641 accaaatcaa tgaggtggga aaatgattaa actattagta gtagaagacg ataaagtatt
     2701 atccaataat ataaaagaaa tactcgctgc aatcggcgag ataacacaag tttatgatgg
     2761 tagtgaagga ctgttcgagt tggaaagtgg agtttatgat cttgcaatct tggatttgat
     2821 gatgccggaa atgaatggat atgaagtgtt agcaaaaata cggaaagaaa aaatacagac
     2881 tccagtattg attttgactg caaaagatag tttggaagat aagattgaag gatttgaacg
     2941 aggtgcagat gattatctaa caaaaccttt ctatcgagaa gaactgatca tgcgcgtgaa
     3001 agcattattg aaacgctcgc taggtctctt tgatgaaaat gttctgaagt ataaggatat
     3061 cagttgtgat ttaaaaagca atgaagtctt gtataaagaa caagttttgc ccatacaagg
     3121 aaaagagttt gaattgctcg tttatttttt acaaaataag ggaatcattt tgacaaaaga
     3181 gcagatattt gaccggatct ggggatttga ttctgatacg acgattacag ttattgaagt
     3241 ttatatgagc aacttacgaa aacatctgcg aagtactgga ttggataaag aaatcaaaac
     3301 cttacgtaat gtcggttata tactgcaaag ggtgtgatgc aatgaatgga gatattacac
     3361 gaaagcaacg tagtcgcttt tttgcgacaa atgtagcagc atttgctttt atcttttttc
     3421 ttttgggatt cattacttta cagatattaa accaatctgc atacagagaa acagatctgt
     3481 cattagagaa aataaatttt gattctcgaa cagtacaatt agagatacaa agatatcagc
     3541 aaggcgatcc ctttttaaac ccgactcaaa cggaacaaaa cagaacaaac atggaacagc
     3601 cattaatgga accatcaaat gaccgtttta acactcaagt gatcttgtgg tctaaaaatg
     3661 gtgagatatt gaataaagca gctattggtg ggcgtttcaa ccaaatcaaa gaattaaaaa
     3721 tggatacgaa aaatctgaat accatccaaa atattgaatt aaatgaagac agtggctcat
     3781 ctgccctctc tttccgttcg attacgaaaa aagcggagac gaatcaagat ggcgttgcct
     3841 acatccaaat tttagaaaat acaaatcaaa tcaagaattc attagcgact tttcgcacga
     3901 ttatgatttt gtgtatgatt gttttttgga ttctctctat tggtatcagt tattacttgt
     3961 ctagtctaag catgcgccct attattcttt cttggagaag acaaaaagaa tttgttgaga
     4021 atgcttctca tgaattgcgc acaccgttaa cgattattca aaatagtttg gaacatcttt
     4081 ttaccaagcc taatcatact attattgaag aatccgaaag catcgctcaa gcattgtcag
     4141 agacgaggcg cctcactgga ttgacttcgg atttgctgac aatcgctcgg aatgattctg
     4201 atcagcagct gctttcaaag caaatgatca atacacaaga atatatcgaa caacttgtta
     4261 aaccatttca agagatggcc atcatagatg gaaaagagtt tattctccat aacgatgcaa
     4321 cattagaagt accaattgat gaaaaaaaaa tccatcaagt tttggttatt ttgctggata
     4381 atgcattaaa atatacgaat ccagaagata agatcatttt ggattcatct gttaaccata
     4441 aagaatggct gattcacgta aagaatactg gcccttctat cagtgaagaa gatcaagcaa
     4501 ggatttttga tcgattttat cgggaagatc aatctcgggc gaaagagact ggcggatacg
     4561 ggcttggctt ggcaattgca aaacaggtaa tcgaacagca tcatggacag atttctgtat
     4621 ccaattatct tccacaagga gtcgatttta aagtccaatt gccgttgaag cctaaaaaat
     4681 aatgcttatc cctaaaaaag ggctgtgaca aaaatcttgt cacagccctt ttttgttgcg
     4741 aataaacggt gttccagaag tagcttcttc ggaaataagc cgaaatttct ttaagctgac
     4801 cacttctgtc acaacctctt tagcttacgc ttacgatttt ttattgcggt cttcaatgtg
     4861 tacatcaccg cttgtgtcaa tatccaattc ttctcggcta acatcttctg tcactttttc
     4921 aacatcttca tgttcttctt tatgaatccc aacttcttca cgaataactg tatgtttgct
     4981 tacatctact tgctcttctt tgattgggat agtaatcgtg tcatcttcca atttttcgtc
     5041 tgttccctgt gaagattgat ctgttactgg tttgcgttcg atgacgattt cttcacgttt
     5101 gaccggtact tctaccgttt cagtatcgtt gaccacatgt ttgtggatgt cgacttctcc
     5161 agttgtcaca tcatgtgtat ttacatctaa tttttcttct tttagttgaa ttgtatcatc
     5221 atctagattt ggtttgcgat cgatgtcttc agtcttgctt gtacccattg tatcagtctc
     5281 gccaggtacg tccatcggat cagttcctgg tgtcatattc aatggatccg ttgtattttg
     5341 aaagcctgtc gtgccaccta cgtccattgg atctgttcca gtgccagttt ctaatccagt
     5401 ccccattgtg cttgctgggc taacagtatc ttgtgtatcc attgtatctt ctgttgtttc
     5461 tggctgacga tagcctttta ctgtgatgac aaattttcca tcagaaatat ctcctctata
     5521 ttgatataaa ggatcatttt ctggtgtagc cgtctcagaa tcataggtat caaaagaaaa
     5581 agtatctttt attttttccc ataaagaacg gtcttcttca ccatccatcc gattttcatc
     5641 tgtttcaaca tctataccag acaatccgtc aaatcctagt ctagatgctg cttcatcagt
     5701 agtataaata acgatatcat ctcgttcata cccttcgtta cgcaaccgtt caattactga
     5761 taatgcttct tccctcgtac tatagcttcc gatgaccgtt aaatttttct cttccatgta
     5821 aattcctcct agcaaataga tttatgattg gtatattgtt acttataaat ttattctata
     5881 ggagacgatt gttttctaca aatatttaga ttggaatttg attaaaacaa tttaattgaa
     5941 atttgaaaac atttatgtta atgaaagtca tattctaata aaatgtcatt tgtttctata
     6001 tgaattttta tgaaaaaatt catataattt ccactcgttg tgatggttta atttatccaa
     6061 tccatcaata agcaaacaac ttatataaaa aaggattaat tctcaatata attgctccta
     6121 ccatagaata aatcttcatg taaagtaatg aagtaccaac tatttctaat acttctttaa
     6181 gaattatccc aacaatatcg ttagacaaac cattattgaa taaatggaga gccaatcgat
     6241 tctgaaaaaa tgttttctaa tttttcggaa ataaaagaaa gagcctcctg ccattagaac
     6301 gaaccaaatc catttcattg ctcatgaagt aaccacatag ctaaaaagag gataaatcaa
     6361 ttaaaagatc aaaagaatga ctgcactaat aaaataacta aaaatgtatc ttcttacttc
     6421 atatctttta gctagtactt agttaaaaat ttgcttccta agatcaagac aaactgtcta
     6481 tcttcatttg atgaaatgcg gtaaaatata gaaaatgaac actattggag ggaatttgta
     6541 atggacagca aaactagaaa acaactgcaa gaaaagttaa agcaacgtac acacttgctc
     6601 ccttccgtct ttcaacagtt tttagaagaa aatcgttctt ccctttcatt aggcagtcgc
     6661 tatgaatacg caaaagattt tcatctgttt actgattatt tgagaaaagt attttctgaa
     6721 gaagtggatg atcagctgat tatccattta gaaaaacaag attatcagaa tttcttagct
     6781 aaaatctatc gacatactcg ttcgttccaa actacagcga accaagaaac ggagcaattg
     6841 tttgaaaata gctattacgg gatttcaagg aagcaatatt cattaaatca ttttttacga
     6901 tttttgtatc aaaaaggact gattgaagaa gagatttctc ttttgggtac aagtttaccg
     6961 gaaacaacca aagcagctcc gcgatatatc gatgcagaac ttttcaaaga ttttgagcat
     7021 ttgtttatcc cgattgaagg ctttcaaaca agcagagaag ctagctttga agaaaagaat
     7081 agaccgagga accttgcaat tactgccatt cttctgtatt gcggattaaa gatccatgaa
     7141 gtagtagaac ttaaacgtaa agatgtatct ttgaccaagc agattcttaa tctgaataga
     7201 aaagaaaaca gactgaataa agtaccaata ccaaaagaag cgatgccatt tctggagaac
     7261 tattttaagt taacagcaca aaatacggac gaaaattctt ttgtttttcg ttcctcacat
     7321 gatcagcaaa tttctcctcg gactattcgc caaattttga gcaaaattac agtatataaa
     7381 aacgtatcgc cagaactatg cagaaaaaca tatcgttatt atgcagaact atatttagat
     7441 gatgctgacg cggtaaatta tttatgtggt aatcgatacc tctcatccca ttcttttcaa
     7501 gatatctggg aaaagatggt tgatttttct tatcacgaat tagcggcatt cgttcgggtt
     7561 tcttccatat aaaacaaatg tatgatcttt ttttcacaat aaactatgtt attatataaa
     7621 ggattatgtt acgattatct tgaatttgta tattacttaa caaaagataa tggagtgtga
     7681 atgatggaga ccataacgta ttcccctttg aacttattta cgaattttca agaagctgca
     7741 gctaactttt ccgagacccc gattatcttt gatgagccac tttcagcttt cccagaatta
     7801 ggacttgaaa caacttacaa aaaatgctgc gaaagtgtgt tgaaacgggc ttatcaattg
     7861 gctcatcttg gagtgaaatc cggagacaaa gttattattt ataagagttc cgcttttgac
     7921 acataccttc tagctgtttc tgtgtcttac cttggtgcag tgcctgtcat gacttcttat
     7981 catctaccaa caacaacaat ggaagtattt atcgatcgtt tagaagaccc tttcatttta
     8041 tttgatgatg agacaaaaaa gcgagtgaga gaaatttcaa atggaacaaa atcaaaacag
     8101 attc
//
LOCUS       DAPBAF010000081         7598 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.085, whole genome shotgun sequence.
ACCESSION   DAPBAF010000081 DAPBAF010000000
VERSION     DAPBAF010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7598)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7598)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7598
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.085"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(941..1354)
                     /locus_tag="RD451_002672"
     CDS             complement(941..1354)
                     /locus_tag="RD451_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HDT7567875.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(1810..2295)
                     /locus_tag="RD451_002673"
     CDS             complement(1810..2295)
                     /locus_tag="RD451_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567876.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(2434..2649)
                     /locus_tag="RD451_002674"
     CDS             complement(2434..2649)
                     /locus_tag="RD451_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HDT7567877.1"
                     /translation="MKTLDAIALTLLIVGGLNWLLVGLFELDLVAMIAGGSTTIFAKI
                     IYIVVGICAIYCLKFFPMITRKVDERY"
     gene            2873..3673
                     /locus_tag="RD451_002675"
     CDS             2873..3673
                     /locus_tag="RD451_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDT7567878.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            3692..5560
                     /locus_tag="RD451_002676"
     CDS             3692..5560
                     /locus_tag="RD451_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HDT7567879.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            5553..6044
                     /locus_tag="RD451_002677"
     CDS             5553..6044
                     /locus_tag="RD451_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HDT7567880.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            6032..6586
                     /gene="srlA"
                     /locus_tag="RD451_002678"
     CDS             6032..6586
                     /gene="srlA"
                     /locus_tag="RD451_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327877.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HDT7567881.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            6604..>7598
                     /locus_tag="RD451_002679"
     CDS             6604..>7598
                     /locus_tag="RD451_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HDT7567882.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVSTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         2707 a         1213 c         1443 g         2235 t
ORIGIN      
        1 tgttactatg aataacataa taagaaagta aagtggattg atttgagatc tttttatact
       61 tcaaaaaaga taacacccaa ctttcaaaaa tatgttttgg aagttgggac aaacgagtta
      121 atacatttta atacattatt ttttattcaa aaaaaatagc acaatggcaa agatcgtaag
      181 agagatcata agccccaatg aatgactaaa aagaaaagca gaatcacatg ccatatcatc
      241 ccatatttct tcaagaaaat aaataagcgg gaaaaaggga aggaatagta gaacatcgat
      301 ccagcaccat ttttttcttc ttttgaaata acataaaaca ataaacatga acgtgcaggg
      361 aagtaaaaac aaagctttac tcataactaa caaaatacca gctcctttta tttttttctc
      421 ccccacattc aaagagtaac aatggtatgt acttaataat agaaaaatgg atcaacttgt
      481 atgaataaca gctgaaaaga tctgcaccaa ataaaaaact tccagccaaa actgactgga
      541 agtttatttt tttctgaaat attctaacac aaatatgaaa aagatggccg aagctaataa
      601 gccgatttcg tagcaaaaca atgagatacc agagtcgtaa taataaaatc ctctaatctt
      661 atggataaaa tagatcatcg gacaagcaga taagagtaag tatttgttag gccttttgaa
      721 taagtaaaag aaagcactgg tcattatgat aaatggtatc caaaacaaaa gtttacttaa
      781 gacaatcaaa tgatcaactc ccatattttt taccaagaga gatcataaca tctttatcgt
      841 aaaaacaaaa tatttttttg ctcattttga aaatttaaac atactcgttc ttatccaaat
      901 atataaaaat cgcccctcat tcatcgagag gcgataagtt ctaatttaac tcaatttttt
      961 ttgtttcttt tggctgataa gctgttttag gtaataccaa tttcagcaca ccgtttttaa
     1021 aggttccagt gattttttct tcatcaacat taggaagata gaatgaacgt ttgtaagaga
     1081 ccgaatgtct ttctttccgt acatagttgc catcttcttt atcttctgta tgggactcat
     1141 gattggcgga gatcgtcaaa gtattatctg aatattcaac tgtcgtgtct tctttgtcac
     1201 agccaggcat atcagcagtt agtttgtatt ctttttcatt ttcgactaaa tctacttttg
     1261 gataacttga aacacctaaa aaatcattga atgctggact aaacacgtca ttgaaatcag
     1321 ggaacatgtc gcgaatgcta ggtacatttg ccatttttga tcatcctttc aataagtatt
     1381 ttttatttat ccctatttac gtaataactc tattttgaaa aaaatgcaag tataatggtt
     1441 agctttgtga atatttcatc taatacgata caaaggctat ctttctaatt tgaaaaaggg
     1501 atcattaaaa taataagaag aaaatatgtc aaaaggtaaa aaagtaaatt cttctatcca
     1561 aatatagaaa aattgaatct agaaaaccgc ccgacaataa atttcattaa ctcagttgac
     1621 cgaaaatgaa gtagatacca aaaatttatc aagagagcaa gtagagaagt gagtatattc
     1681 ataagagaaa tagctgtaac gaattattag gttaatgcaa atgcttattt atactccgta
     1741 taactttctc agaaaaaatg ataccaataa tgacttgcta gtactgtaaa tccgtataat
     1801 atcatctaat caaaatggtg ttccatttgc atctgtcatc gtaatcgatc cttcgggtga
     1861 cactcgataa aaaccaacgc ttccagatcc tccttgggaa cggatttgtt tgctggaagc
     1921 tgtgaacaaa taatctcgat caattttttg ataaaagcta ataacaatat cgtcactttg
     1981 taattcggaa cggtgggcaa taagaaatag aagtgctttg tcagagtttt ctaatggaag
     2041 agaaggtaca gtgctttctt gcatttcaga tgttgaagaa atgctaaacg actgaatact
     2101 tgattggcta tgttgcgaat ctacattacc agtagaagta ttagtaatgg aagtagtaga
     2161 agtactttta gttgaaccaa cctcagttgt tgaaatggct gctgaagatt ctttaacaga
     2221 attctttgtt ttatatccac aggcagaaaa aagtattaca gttcccaaca agcctgcgta
     2281 aatcccttta tgcatgatag ctcctcctaa aatagattat ctttattcag tatatcactt
     2341 aaacaaagaa aagcagatgg tttaaaatga aaaaaccttc ccaataaagg gaaggttcat
     2401 gaagataata acttttttaa taattatagc tttctaatat ctttcatcaa cttttctagt
     2461 aatcattggg aaaaatttca agcagtagat cgcacaaata cctacgacga tataaatgat
     2521 cttcgcaaaa atagttgttg aaccaccagc aatcatagct actaaatcaa gttcgaacaa
     2581 gcctaccaac agccagttca accctcccac aatcaataaa gttaatgcaa tagcatctaa
     2641 agttttcatt agaattctcc tttcttaaat gataaaacaa ttatatatca aaaagagaaa
     2701 cattgcttat ataacgctca ggaattttag caatctatgc aaaaagatga aaattttttt
     2761 tgctcttcca ttagtacaca ttttttagct gaagctgtaa atttcatgtc ttaatttttt
     2821 ttagtgagct tttatactgg atttgtaaga aaaaagaagg agaggatcac atatgtcgga
     2881 ttggttggat attgcaggaa aagtagtaat tgtaactgga ggttcctcag gaattggaag
     2941 aagtatcgtc gaaaatttgt tgaagcagaa tgcacaagta gcgaattttg atgtaactga
     3001 atgccgtata cagcatgaaa acctactatc tttaaaagtc gatgtgtctt ctaaaacgga
     3061 catagaagaa gggatatata aagtaatgaa acatttcaag acgatcgatg gtctagtcaa
     3121 taatgcagga ataaatattc cttctcttct aatagataga aatcatccaa aaagcaagta
     3181 tgaattatca gaacaagttt ttgataagat gatcgctgtc aatcaaaaaa gtgtatattt
     3241 gatgagccaa gcagttggaa gaatcttggt gcaaaaggga tcaggagtga tcgtgaatct
     3301 ttcttctgaa tcaggattgg aaggatcaga aggacagagc tgttatgctg ctacaaaagc
     3361 agcgatgaac agttttactc gttcttgggc aaaagagtta ggaaagagga atgttcgtgt
     3421 ggtaggtgtt gcaccaggga tactggaaga aaccggtttg agaacacaag aatatgaaga
     3481 agctctttct tatacgagag gtataagcgt cgaacagctg agaaacggtt acagtcgaac
     3541 aagtacgatc cctctaggaa ggagtggtaa gctgcaagaa gtggcggatc tagtctgcta
     3601 ttatctttca gaaagatcaa gttatatcac tggagtcacg actaatattt caggaggtaa
     3661 aacaagagga taaaggatag gggggacgca cgtgacgcta gtaaacagat ggtaccaatt
     3721 attgaaatta ctagtcactc acaagaaagt ttcaatccag gaagtgcaaa aagaaatcaa
     3781 aaccagtaat caaaccataa aaaaagatat tggggagttg aatgaagaaa ttgccggtat
     3841 tgcaaaaatc atccaaaaaa acaaacattt tgaacttgaa atttatgatt ttgatttttt
     3901 tgatgagatc atgcaaggaa aattgaaaac agccagtgat ttcaattcgg catccaaaag
     3961 aatcgcttat ttactaaata ggctgatcga aacagaggat ttcttacgta tggatgattt
     4021 gtctgaagaa gtcggtgtca gcagaggaac agtggtcaag gatctaaaga cattaaaaga
     4081 gatgatcaat gattttgatg taaagattac aggcacacca aataaaggac taagaataat
     4141 aggagatgag ctagaattac gactactttt attttatttt gtttctccct acttttcaga
     4201 gacgaaaaca gaacagtttc tagaagaaaa acaagcaatc aaacattttc agaagaagac
     4261 gaatgctagt aaacaagaaa tcaccctttt aacgaaagtt atcggtattt ctttgaatag
     4321 aatctctagt aactatctgt tgaagaagcc catcaatcgt tacagtgggt gttttgaata
     4381 tatccaagaa ttcaatgaac tgatcaatca gttggaagaa atctatgaac taactttgag
     4441 ccaatatgaa aaagatttta tcagttttcc tttgaacatc atcaacacaa gtataacgat
     4501 gataaggaaa gctaactctg atttgcgctt atatttcgac cccatgatga tgcgtattcg
     4561 acgattagat ctcattgatc tggatgagtc cttcttatat caagagatga aacagcacct
     4621 ctctttattg ataaatcggg taatttttcg ttatcgattg actgatttat tttatggtga
     4681 gatagaaaaa aagtatcctt tttcttacca aatcgctagc gaatgcatac aagcattaga
     4741 agctatcttg caacataaga tctctaaagt agagatcagc tacctaacgt tgtatttgga
     4801 gttagcattt cgatatcaaa aagagcattt ttcctctaaa aaagtagcca ttgttcatac
     4861 gacaggaaaa ggaacagcat taatgatcca aagacaaatc aaaaggatat tggggaggga
     4921 tatacaaata acacatgttt cagaagaaca atatgaaaaa gtagatctaa acaaatattt
     4981 cgctgttttt acaacgattc cgttaaaaaa tgtaaatgaa gagacaccgg tgatccattt
     5041 gactaatctt tttgatgact cttggttaag ggcacaatgg caaaaagcaa aaaaaaagcg
     5101 attagccggg tttcattcta ctgttttttt ctatcaaata tggaaagaaa aaaagacgta
     5161 tcaagaatat ttaaacaaat tagtcgctcc tttgatcaga ggctattatg tggatgaaga
     5221 atttgaaaaa aggatcttga aaagagaata tcagcaaagc acatttgtta acaaagaatt
     5281 tgcttttcct cacacaacca accagctatc tcaacacatt gttttatcag tagggctaat
     5341 aactgatcaa ggtttagcag aaacaggagg aaatggagtt atttttttat ttgccatacc
     5401 tgaagaaatg acggctgaag ttgagaatga attatttgag ctatacgata tcctatttga
     5461 actcataaaa atgggaatag atgagtttat tgaattagca ccgacacaag aatcattttt
     5521 aaaactaatc aaaagtaaag gagagagact tcatgaatga tatgtatcta ttcatagttt
     5581 tcgcagcttc agcttatgtg ctgcaagcag ttatcagttg gaagcaacta aagcatttca
     5641 atcaaacata tagcgaactg cgaagaaaag gaaaagtagc gattggtaaa cgacctggga
     5701 aaatccgttc aggcacgatt gttatgctag ctatagacga tcatgatcaa gttttagaag
     5761 tcagaaaaat gcaaggggtt acatctttgg caaaatttca ttcattacct gtctatgcgg
     5821 gtgaagatat ccattacatc gatcgttacc atccctcagt tcgagcggaa gatcgtttga
     5881 cacaagcagc tttagaaaat gccagagaag tatacttacg aatagaggca ggaaatgaaa
     5941 aaagtgaaca accttcattg ccttttattg ctatgctcaa taattttcgg atatggaaaa
     6001 gtacgatcaa agaaaaaagg agtgacaaac gatggatatc ataacaaaat ttgctgaggg
     6061 atttatgagg ctgttccaaa caggtgcaga aacattcata agctggatga caggaatcgt
     6121 accagttgtc ttgatgctga tggttgcaat gaatacgctg attgcttttt taggtgaaga
     6181 ccgagtaacg aaagtagcca aattatcagc gaaaaatccg cttactcgtt accttgtgtt
     6241 accgttctta tctgctttta tgttgggaaa tcctatgtca tttacaatgg ctcgtttcct
     6301 tccagaatac tacaaaccaa gctattatgc tgctcaagct caattttgtc atacgagcaa
     6361 tggtgtattc ccccatatta atcctggaga attgtttgta tggatgggga ttgctcaagg
     6421 gatcgaaacc ttagggctaa attcgatgga gctggctatc cgatacttgc ttgtgggact
     6481 gctgatgaac tttattggtg gttggataac tgattttact actggatttg tatgcagaca
     6541 gcaaggaatc gttcttagca aaaaagtaga gctttcagtt gattagagaa aggagagttt
     6601 taaatgtatg gtgatattaa gatcgtaaga ggaaacggcg ggtatggagg tcctttgatt
     6661 attaggccga caaaagataa acacaagttc atctatgtca caggtggagg tgagaggcca
     6721 atgatcgtag ataaaataga agaactgaca ggtatggagt ctatcaatgg gttcaaaaca
     6781 tcaatacctg atagtgaaat cgcgcttgca atcgttgact gtggagggac tcttagatgt
     6841 ggaatttatc ctaaaaaagg gataccaacc atcaatatcg tttccacagg aaaaagtggc
     6901 ccattagcac aatatatcac tgaagatatt tatgtttcag cagtagggtt agaacaaata
     6961 cagccactaa tggaaactga tgataacaaa gaaacagtaa atactgcatc tccagataaa
     7021 aagtacaaat atgatacttc taaaaagata accgagcaaa aagcagagca gcaaaactgg
     7081 atagcaaaaa ttggaatggg cgcgggaaaa gtagttgcta cattcaatca atcagcaaga
     7141 gaagcagtag atacgatgat ccggacagtg atccctttta tggctttcgt ttcccttttg
     7201 attggtgtga tacaaggttc tgggatcggt aatgtatttg ctaacattat ggcaccttta
     7261 gcaggaaatg cagttggatt aacaatcatt ggctttattt gttcactgcc atttttatct
     7321 cctttgcttg gtccaggggc agttattagc caagtgattg gaacattgat cggtgtagag
     7381 attgggaaag gaaatattcc tccccaatta gcattaccgg cactatttgc tatcaatact
     7441 caaaatgcat gtgattttat tccagtcggt ctaggtttgg aagaagcaaa agctgagaca
     7501 gtagaagtag gtgtaccatc agttctttat tcaagatttc ttaacggcat cccacgagtt
     7561 atcattgctt gggtagcaag ttttggatta tatagctg
//
LOCUS       DAPBAF010000082         7153 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.086, whole genome shotgun sequence.
ACCESSION   DAPBAF010000082 DAPBAF010000000
VERSION     DAPBAF010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7153)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7153)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7153
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.086"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(<1..1368)
                     /locus_tag="RD451_002680"
     CDS             complement(join(<1..795,795..1368))
                     /locus_tag="RD451_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEfa10 family transposase"
                     /protein_id="HDT7567883.1"
                     /translation="MAKYTFELKLKIVHDYLDGKGGSDYLAKKYSIKAPSQVKRWINA
                     YQEFGEEGLVRKRQKKKYSVQFKLDAIELYLTSELSYREVANTLNMNNPNLIASWMRQ
                     FREGGIDGLSKTKGCPPILSKKNEPKNKKKSTTKATSKERERIEELEKRVRSLQIENA
                     FLKELRKLRKQEAQQRRMKQSHESSQASEDRFKLVELLETLKFPKAIFMYWQKRLDRK
                     NPDQEIEAEMLKVREKHKDYGCLRMTNELRNRGFSINKKKVQRLIKKLGIKVTTYTRK
                     SRRYNSYRGQVGAVAKNRIHRRFYTSICHQKITTDTTEFKYHEVDAKGIIRQKKLYLD
                     PFMDMFNSEILSYRISEKPNALAVMEGLEEAIQTTNDCPYRRTFHSDQGWAYQMKAYR
                     NKLKEYKIFQSMSRKGNCLDNSLMENFFGLLKQEIFHGKVYNCFEELKSAIDSYIYYY
                     NNERIK"
     gene            1611..2066
                     /gene="tnpA"
                     /locus_tag="RD451_002681"
     CDS             1611..2066
                     /gene="tnpA"
                     /locus_tag="RD451_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HDT7567884.1"
                     /translation="MSNDDKSLAYTRWNCKYHIIFTPKYQRKVIYGQLRKDLGKILRK
                     LCEMKDVEIIEAHAMLDHIHMLVRVPPKICISSFMGYLKGRSAVLIHEQHANLKYKYG
                     NKSFWSKRYYVSTVGLNQKTNEKYIREQEADDRIRYIISKREYVEPFKK"
     gene            2331..2429
                     /locus_tag="RD451_002682"
                     /pseudo
     CDS             2331..2429
                     /locus_tag="RD451_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(3112..3930)
                     /locus_tag="RD451_002683"
     CDS             complement(3112..3930)
                     /locus_tag="RD451_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDT7567885.1"
                     /translation="MSYIYLIKENYPFLTKSEKKVADFILNSGKTIIYSTMSDIKKNT
                     KVGDATIIRFCQKIGFSGFSDLKIEIAKEDFSQKKEHPTSVKYYDEIANSLTEALYST
                     IRLLDEEKLNEAIKMITQSKNIYIFGVGSSGNTSLDLENMFLRVGVQAKAVLDPHFQA
                     QVASLLTVNDLVIIFSLSGKTKDTYDSLKIAKKNGAKIIAITNYIHSPIGKSADLVLQ
                     TAIEEFLNGGSLAGKISQLYICDLLVHGYEQNNNIDSVELREKVLRSIIDKSIE"
     gene            4091..4780
                     /locus_tag="RD451_002684"
     CDS             4091..4780
                     /locus_tag="RD451_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HDT7567886.1"
                     /translation="MDKKRFLDLISKGLIVSCQALPGEPFYKEEESLMPYFALAAQRA
                     GAVGIRANSVRDIIEIRKCVSLPMIGIIKRDYPPESPFITATMREVDELVETGVEVIA
                     LDCTLRNRHDGLSINSFITKIKEKYPHQLFMADISTFEEGKNAYKAGIDFVGTTLSGY
                     TEESKKQDGPDIDLIKKLVEEGICVIAEGRIHTPEQAKEIKKIGVAGIVVGGAITRPQ
                     EIASRFVKALS"
     gene            4794..6296
                     /locus_tag="RD451_002685"
     CDS             4794..6296
                     /locus_tag="RD451_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDT7567887.1"
                     /translation="MFKKFSQLGRAFMLPIAILPVAGLLLGLGGALTNESAINAYPFL
                     DQPWLHTILSIMSYAGNAVFANLALIFAIGIAVGLANGDKGTAGLAGGVAYLVYTATI
                     SGFLELFSAKDATLDTGVVGSIVVGGTVAFLHNRYRKIELPQFLGFFGGSRFIPIVSS
                     LAAIIIGSFFYLIWPPIQNGLVVAGEQIAQMGSLGTFLYGFLLRLTGAVGLHHTIYPL
                     FWYTSLGGTETVAGSTIAGAQNIFFAQLADPNHTGLFTYGTRFFAGRFATMMFGLPAA
                     CYAMYRAIPKKNRKKNGGLYFSGALTSFLTGITEPVEYMFLFVAPWLYVIHAFLDGLS
                     FYFADILNIRVGNSFSGGLIDFLLFGVLQGNDKTNWLKLIPFGIAWAFIYFFVFTFFI
                     KKFKVAIPGMEEESEVHSEKVINKNTSLHEESLIIIEALGGKENIESVEACATRLRVA
                     VTNGEIIQKQTIKDTGATAVFEVKGGIQAVFGGKADLLSQEINQILGKDN"
     gene            6309..6785
                     /locus_tag="RD451_002686"
     CDS             6309..6785
                     /locus_tag="RD451_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDT7567888.1"
                     /translation="MFEIFKKKKQETFYAPCSGKIISITEVNDPVFSQKLLGDGFAVI
                     PDGSKIYAPLAGRVTNIFPTKHAINIKSNSGIDYLIHIGIDTVELQGEPFSICVQEND
                     EVTPETSLVDVDFDKIIKSGKDTSVIVVFPEKNQFNDLIIDNGRIAHGNSCGKITF"
     gene            complement(6882..6992)
                     /locus_tag="RD451_002687"
                     /pseudo
     CDS             complement(6882..6992)
                     /locus_tag="RD451_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2316 a         1131 c         1295 g         2411 t
ORIGIN      
        1 gttttatccg ttcattattg tagtaataga tatagctatc gatggctgat tttaattcct
       61 cgaaacagtt ataaactttc ccgtgaaaaa tctcttgttt taataagcca aaaaaattct
      121 ccataagtga attatctaag cagttccctt tccgagacat gctttgaaag attttgtact
      181 ccttcaattt gtttctataa gctttcattt gatacgccca accttgatct gagtgaaacg
      241 tacgacgata gggacaatcg ttagtggtct ggatagcttc ctccaaacct tccattaccg
      301 ctaatgcatt gggcttttca gagatacgat aggataaaat ctcactattg aacatatcca
      361 taaaaggatc tagatacaat ttcttttgac ggataatgcc tttggcatcc acttcatggt
      421 atttaaattc agttgtatcc gtcgtgattt tctgatggca gatactggtg tagaaacgac
      481 gatggatccg atttttggct actgctccga cttgtcctcg ataagaattg tagcgccgtg
      541 atttacgtgt gtatgtcgtt acttttattc ctagcttctt gatcaggcgc tgaactttct
      601 ttttattgat agagaaaccg cggtttctta gttcattggt catccgtaaa cagccataat
      661 ccttgtgctt ctcccgaact ttaagcattt ccgcttcaat ctcttgatct ggatttttac
      721 ggtccaatcg tttttgccag tacataaaga ttgccttagg gaactttaaa gtttctagaa
      781 gctcaactaa tttaaacggt cctcggaggc ttgcgatgat tcgtgcgatt gcttcattcg
      841 tcgttgttgg gcttcctgtt ttcgcagctt cctcaattct tttaaaaagg cattttcaat
      901 ttgaagggaa cggactcgtt tctccaactc ctcgatgcgt tcacgttctt tagacgttgc
      961 tttagttgta gattttttct tatttttggg ttcatttttc ttagacaaga taggtggaca
     1021 tcctttcgtt tttgagagtc catcgatccc accctcacgg aattgacgca tccaactagc
     1081 gatcaaatta gggttgttca tgttaagtgt gttggcaact tcacgatagg acagctcact
     1141 tgttagatat aactctatcg catccagctt aaattgaaca gaatattttt tcttttgtcg
     1201 ctttcttact agaccctctt caccaaattc ttgataggca ttgatccagc gcttcacttg
     1261 tgatggagcc ttaatggaat atttctttgc cagataatca cttccgcctt taccatccaa
     1321 gtaatcatga acgatcttta atttaagttc aaaagtatac ttagccataa aaaataccga
     1381 cctccaaaag ttagattttt tggtctaact tttgggggtc ggtacaaaac ttaaaagttt
     1441 tagacccttt tattttctta atgacttcag tcagttttgt gcgtaaagcg tgcgaaacaa
     1501 gaaaaccgcg cgtttctacg cgtggaagaa gtatctttag cgataaaaac tcctttcgat
     1561 atactagtga gtggctacca accgctcatc agatcgaaag gagttttttc atgtcaaatg
     1621 acgataaaag tttagcatat actcgttgga attgtaagta tcatattatt tttacaccaa
     1681 aatatcaacg aaaagtaatc tatgggcaat tacgaaaaga tcttggaaaa atacttagga
     1741 agttgtgcga aatgaaagat gtggaaatca tagaagcaca tgcaatgcta gatcatattc
     1801 acatgcttgt tcgagtacca ccaaaaatat gtatatccag ttttatgggg tatctgaaag
     1861 gtcgtagtgc ggtactaatc cacgagcagc acgcaaatct caaatataaa tacggaaaca
     1921 aatccttttg gtcgaagaga tactatgtga gtacagtcgg attgaatcaa aagacaaatg
     1981 aaaaatacat ccgtgaacaa gaagctgatg atcgcattcg atatattata agtaaaagag
     2041 agtacgtaga accatttaaa aaataaagag aagtaagtga gtgaagatga gcagttggcg
     2101 gtcttttaaa aatccccttt taaggggcag cgagtgtcga ccccttctag ggggattaaa
     2161 aatacacccg tcctcacggg tgtatgggtt actgatagac ttgattttaa ctggtgtcag
     2221 aaacttatgt ccagaaaggg tgatgaaatt ttggcaattt acggctattc aagaattagc
     2281 acaagcaacc aagattacaa aacacaaatt caaacattag aaaatgctgg cgcagaaata
     2341 atcttcctag aaaatcactg gattatcgaa cacctttgga agtatttttg agttacgtaa
     2401 gtattgatga tctgtctaac ttaatttgac aattaagagt atatttactt cagatggtaa
     2461 ggcaacaaaa taaaatacaa taggcagatg aactaataaa taaaatctgt attaaataca
     2521 gataaattaa tataaaaatc aaaaggatca taaactttta acaagtgatg aaatgggtgg
     2581 aaattgattc ttatagacag tttgtctcat aacattgaag tattttgcaa ttttagcatt
     2641 gaaacacttt tttaatcttc aacgttgttc ttataaacaa gatgattggg aatcttttga
     2701 attaacactg tatagcttag aacacccttt atagaaaaca ttcgcttagc aatcttaata
     2761 attccttgtg cccgatgtcg tttagattca gtaggttcct gctcatcgat catggaaaaa
     2821 atttgaagga tcagatcctt aataaattta tttaagagag gatgatccat tgcttcatcc
     2881 atactcgata aactagtgat aatgagctac acgtttttct ttcaagttga tcaatagctt
     2941 ccacgataaa aatatcttta gataaaatca agaaccgtag gaactacagg gatatttggt
     3001 caataagagc caccgctatt agtaaaaaat aagctatcaa gtatgctctc atcccaagaa
     3061 ttgcctactt caatcgttaa aaaccgttag gtttagctaa gtgggggtag ttcactcaat
     3121 acttttatca ataatagagc gcaaaacttt ttctcttaat tcaactgaat caatattatt
     3181 gttttgttca taaccatgaa ctaatagatc acaaatataa agttgtgata tttttccagc
     3241 taaagatcca ccattaagaa attcttcaat ggctgtttgt aaaactaagt ctgcagactt
     3301 tcctataggt gaatgaatat agttagttat agcaataatt tttgcgccat tttttttagc
     3361 tattttcaat gaatcataag tatctttcgt tttcccagat aaagaaaaaa tgattactaa
     3421 atcattaact gttaataaag aagcgacttg ggcttgaaaa tgagggtcta gtacagcttt
     3481 tgcttgaact cctacgcgaa gaaacatatt ttctaaatca agactagtat ttccactaga
     3541 tcccactcca aatatatata tgttttttga ttgagtgatc attttaatgg cttcattcaa
     3601 tttttcttcg tctaaaagcc taatagtgga atagagagct tctgttaaac tattagcaat
     3661 ttcatcatag tactttacac tagtcggatg ttcttttttt tgactaaagt cttcctttgc
     3721 aatttcaatt tttaaatcag aaaaaccaga aaaaccaatt ttttgacaaa agcgaataat
     3781 agtagcatcg ccaacttttg tgtttttctt aatatcactc atcgtactat aaataatagt
     3841 tttcccagaa tttaaaataa aatcagcgac ttttttttca gacttcgtta aaaatggata
     3901 attttcttta attaaataga tataactcat acaaactcct ctacaatttc aacttttctc
     3961 cattatactc caaaataata aaaaaaactc ctaaatactc catttttatc tttactttta
     4021 tgaaagcgga tgctatattg tttttggagt tgttatccaa aaataataaa aaattggagt
     4081 gtttaggata atggataaaa agaggttttt agatcttatt tcaaaaggtt tgattgtttc
     4141 ctgtcaagca ttacctggtg aaccatttta caaagaggaa gaaagtttaa tgccttattt
     4201 tgctttggct gctcaaaggg ctggagcagt tggtatacgt gcaaattctg ttcgagatat
     4261 tattgaaatt agaaagtgtg tatcattacc aatgattgga attattaaaa gagattatcc
     4321 accagaatct ccattcatta ctgccactat gagagaagta gatgaattag tagaaaccgg
     4381 tgttgaggta atcgctcttg attgcactct tagaaatcga catgatggac tatctataaa
     4441 ttcttttatt actaaaataa aagaaaaata tcctcatcag ttatttatgg cagatatttc
     4501 tacatttgaa gaaggcaaaa atgcatataa agcaggaata gattttgtag gaactacttt
     4561 aagtggatat actgaggaaa gtaaaaaaca agatgggcca gatatagatt tgattaaaaa
     4621 attggtagaa gaagggattt gtgtaattgc tgagggaagg attcatactc cagaacaagc
     4681 aaaagagata aaaaaaatag gagttgcagg tattgttgtg ggtggtgcta ttactcgacc
     4741 acaggaaatt gcatcaagat ttgttaaagc attaagttag ggggagaaat aaaatgttta
     4801 aaaaattttc acaattagga cgcgctttca tgttaccaat tgctatatta ccagtagccg
     4861 gattactatt gggactggga ggagcgttaa caaatgagag tgctataaat gcttatccat
     4921 ttttagatca accgtggttg catacaattt taagtattat gagttatgct ggaaatgcag
     4981 tttttgcaaa cctagcacta atttttgcaa ttggtattgc tgtaggactt gcaaatggag
     5041 ataaaggaac agctggttta gctggtggag tagcttatct agtatatact gcaactatta
     5101 gtgggtttct tgaacttttt tcagcaaaag atgcaacact agatacaggt gtagtgggat
     5161 caattgttgt tggtggtact gttgcatttt tacacaatcg ttatagaaaa attgaattac
     5221 cacaattctt aggttttttt ggaggatcaa gatttattcc gattgtttct agtttagctg
     5281 caatcattat tggttctttc ttttatttaa tttggccacc aattcaaaat ggtttagtag
     5341 ttgctggtga acaaattgcc caaatgggta gtttaggaac ttttttatat ggttttttat
     5401 tgcgtttaac aggtgctgtt ggactacacc acaccattta ccctttgttc tggtatacat
     5461 ctttaggtgg taccgaaact gtagctggat caacaattgc tggagcccaa aatattttct
     5521 ttgcccaact agctgatcca aaccacactg gtctgtttac ttatggtact agattttttg
     5581 caggaagatt tgcaacaatg atgtttggat taccagcagc atgttatgca atgtatcgtg
     5641 caattcctaa gaaaaatcgt aaaaagaatg gtgggcttta ttttagcggg gcccttacat
     5701 catttttaac tggaattact gaaccagttg aatatatgtt tttatttgtt gctccttggc
     5761 tttatgtgat tcatgcattc ttagatggat tatcttttta ttttgctgat atcttaaata
     5821 ttcgtgtagg gaattccttt tcaggtggtt tgatcgactt tttattattc ggtgtacttc
     5881 aagggaatga caaaactaat tggttaaaat taattccttt tggtattgca tgggcattta
     5941 tatatttctt tgtttttaca ttctttatca aaaaatttaa ggtagctatt cctggaatgg
     6001 aagaagaatc agaagttcat tctgaaaaag taataaacaa aaatacatca ttacatgaag
     6061 agtctcttat cattattgaa gctcttggtg gaaaagaaaa tattgagtct gttgaagctt
     6121 gtgcaactcg tttgcgtgtt gctgttacga atggggagat tattcaaaaa caaacaataa
     6181 aagacactgg tgcaactgct gtcttcgaag tgaagggtgg catccaagct gtttttggag
     6241 ggaaagctga cttattaagt caagaaatca atcaaatatt aggaaaagat aattaggagg
     6301 tttttaatat gtttgaaatt ttcaaaaaga aaaaacaaga aactttttat gcaccttgtt
     6361 ccggaaaaat catttccatc acagaagtaa atgatcctgt cttttcacaa aaattactag
     6421 gtgatggttt tgccgtcata cctgatggtt caaaaattta tgctccattg gctggtcgag
     6481 taacaaatat atttcctact aaacatgcta ttaatataaa aagcaactca ggcattgatt
     6541 atttgattca tattggaatt gatacagttg aattacaagg agagcctttt tcgatttgtg
     6601 ttcaagaaaa tgatgaggtt actcctgaaa cctcgttggt tgatgtggat tttgacaaaa
     6661 taataaaatc tggtaaagat acttctgtta tagttgtttt tccggagaaa aatcagttca
     6721 atgatttaat aatagataat ggtcgaattg ctcatgggaa ttcatgtgga aaaatcactt
     6781 tttaaaaaag tgtatataaa aagctataaa ataagctaaa taggatattt gtcaaatgaa
     6841 gttggtgaac agaaagaact gttttctttc tgttcatttt tttattttat tagtaatgat
     6901 tccccatgcc aaatcatgat ccgtaattta aagttataaa agcttcgaaa tccattggca
     6961 tttcgttgga ataccttgat atgattattc aaatataaaa tatagagaga agagagagag
     7021 ggaagatatt tataaagggc aaagttatgt ttactcaact taggaaatag aaatagatca
     7081 atttatattc tcttgtcaat cgaatatgaa ccttagcact atataccaaa tatagtaaaa
     7141 tgctgaaaga tgt
//
LOCUS       DAPBAF010000083         7082 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.087, whole genome shotgun sequence.
ACCESSION   DAPBAF010000083 DAPBAF010000000
VERSION     DAPBAF010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7082)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7082)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7082
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.087"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(23..475)
                     /locus_tag="RD451_002688"
     CDS             complement(23..475)
                     /locus_tag="RD451_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HDT7567889.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            625..1575
                     /locus_tag="RD451_002689"
     CDS             625..1575
                     /locus_tag="RD451_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HDT7567890.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            1568..2527
                     /locus_tag="RD451_002690"
     CDS             1568..2527
                     /locus_tag="RD451_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HDT7567891.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            2524..3279
                     /locus_tag="RD451_002691"
     CDS             2524..3279
                     /locus_tag="RD451_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDT7567892.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHIGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            3302..4255
                     /locus_tag="RD451_002692"
     CDS             3302..4255
                     /locus_tag="RD451_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HDT7567893.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(4899..5195)
                     /locus_tag="RD451_002693"
     CDS             complement(4899..5195)
                     /locus_tag="RD451_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HDT7567894.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            5550..5906
                     /locus_tag="RD451_002694"
     CDS             5550..5906
                     /locus_tag="RD451_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HDT7567895.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            5916..6815
                     /locus_tag="RD451_002695"
     CDS             5916..6815
                     /locus_tag="RD451_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HDT7567896.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
BASE COUNT         2167 a         1205 c         1421 g         2289 t
ORIGIN      
        1 aaaatttatg tgttttttcg ttttaaaata aacgatccca gaagcttttt ttcttttttg
       61 gtttttcttt ttcagctggc gaagagtttt cttctgggta ttttttttcg atatcaatca
      121 caggttcatt tactgcttct tttgctgtta agagcaatcc gaattcctca ggatttgcag
      181 tgacgtaatc gttgactaca gtgaaacggc tattgttttt cgttgctagc tggatatatt
      241 ggttttggac agaaaggggt agagccccat tcaagagtat ggaagcatct ggatgttttt
      301 tgagttcttt taaaaagttt tctttgtttt ttggttggat catttcagca acagtcatac
      361 taagatagca gcgttccctg aatgtcccta aatatttatg ctgttcttca gggttcacta
      421 aaggtgtacc ataaagtccc ttatccaaat ggctttttac atcatcttgt gccataaaaa
      481 ataccctcct tcttctcttt gtctttctta cgattatagc atattcccaa taatacctaa
      541 aacatatgaa aaagcggttg cttttgttca acgattcact taaaataaga atgaaaatca
      601 ttctcaatta gaaaggtgga ttggatgcgc tacggacgac tagtagcatt attagttatt
      661 ttaagtagta tttcattgtt catcggagta tcgaatgtac aattgtcaga actgctccag
      721 ttagatgggc aaagcttaca aatcttgcta gtgactcgtt tgccacgaac gatttgtttg
      781 atccttgtgg gagcgaccag tagtatttgt gggttgatca tgcaacattt gacccaaaat
      841 aaatttgttt caccaacgac tgcgggcacg atggatagtg cgcgtttagg tattttagtg
      901 gctatgattt tcctacctgg tgcatccttg attgtccgat ccttgacagc attttgcttt
      961 gcttttgcag gaacattgct ttttttatcc cttacgcgat tgttcctcca gaaaaatcaa
     1021 ttgatgcttc cgttgattgg agtcatgtta gggaatatca ttggttcagt tgctactttt
     1081 tttgcttatc aattccagtt ggtacaaaat atgacttcat ggcttcaagg gaattttgcg
     1141 actgtgatac gaggaaatta tgagttattg tatgctgttg ttccattgtt gctcttggtt
     1201 tggctatttg cttaccgatt tacgatcatt ggtctgggcg aatcgtttgc agtaaatctg
     1261 ggaatagatt accagaagat gcagttttta ggcattggct tagtatcatt ggctagtgca
     1321 gtcatgttga tcatggtagg aagcattcct tttatcggag tgatcattcc gaatcttgtc
     1381 tctagaatat atggagatca agtgcacaaa acaattggcg taactgcttt agcaggtagt
     1441 ttgttcttag tattttgcga tcttgtcgct cgcgtgttga tttttcctta tgaaatacca
     1501 gtcagtgtga tcgttggaat catcggtggg gctatcttcc tttatcttct gataagggga
     1561 cgacgatatg cttaaaaaaa agccatctat ttttattggt atgcttgttc ttgttttatt
     1621 tgttacagga atgtacttga cgatccatac atatggaaac tggcattttg catgtgcatt
     1681 gaggagtaag aaaatttttg catttatcct tgtctcgcta gctgtcagca gtgccacaat
     1741 cagctttcag acaattacgc ataaccagtt tttgactcct tcagtattgg gacttgagtc
     1801 gttatatgtc cttgtccaaa cggtcctttt cttctttatc ggaggagtga cgatgcttca
     1861 gcagacaggt acagtttttt tcttattgaa cgttgggctg atggtcgggc tgagtctatt
     1921 gttatttttc tttcttttga aaaaaatgag agcgaatctt tttttattac tgatgtcagg
     1981 gatgatttta ggtacgcttt ttggtagtgt cagtaccttt ttacaagtca tcatggatcc
     2041 gaatgaatat gatttgcttc aaggcagatt atttgcaagc tttggcaata tccagagtca
     2101 gtatcttttg cctgcttctt tgatcattat cggctgctgg tacctgttat ttcgatatcg
     2161 acatgtgcta gacgttttcc atctcggaaa tgaacaagca gtaaacctcg ggatagacac
     2221 agatcgtttt gaatttttga ttttatgttg tgtcagtctt ttgacaggga catcaacggc
     2281 tcttgtgggt ccagttactt ttttagggtt tattgtcgca aatatcagtt atcgtgtctt
     2341 ttctacttat cgtcatggtc agctatttat cggaagcttt ctggtagcta tgctgtttct
     2401 gacaggagga cagctcgcag tagagcagat tttcggctgg aatacaacag tgagtgtcgt
     2461 cgttgaattt gtcggaggaa tttattttgt cacaaaattg attcgcgaaa ggaagagtat
     2521 cctatgattg atttacaaaa ggtcaataaa ctgtaccatg gaaaatcagt ggttaaagat
     2581 gtacagttaa cgattcctga aaagaagttg actgctttta tcggtccaaa tggtgctgga
     2641 aagtcaacgg tgttgtcgat gatcagtcgt ttgataccaa aagatacagg tgaaatctat
     2701 ttagaccata acgaagtaaa ggcttggaaa tccaatgaat tagccaaaaa attatcgatc
     2761 ctacgacaat cgaatgaaat aaatgtccaa atcaccgtga aagaattagt agaatttgga
     2821 cgatttcctt atacgaaagg aaaattgacg acaaaagacg aggaaatcgt tcaggaatca
     2881 ctggaacaca ttgggttaga agaaatagcg gatcaatcga ttgacactct ttcaggcggt
     2941 caactccaac gtgcgtatat tgcaatggtg ctagcgcaag acacggatta tattttactg
     3001 gatgaacctt tgaacaatct agatatgaat tttgcggttc aaatcatgca gattttaaaa
     3061 aatttagtac aagaaatcgg gaaaacaatt gttattgttc ttcatgatat caactttgct
     3121 gcaagttatg cagacgaaat tgttgcaatg aaagatggac agttatttac gcaaggaacg
     3181 acccaagaaa tgataaaaaa agatgtattg gatgaattat acgaaatgga catacggatt
     3241 tgtgagattg aaggccgcag attctgtctt tatttctaaa actaacatta ggagagaaga
     3301 gatgaaaaaa ttagtagtag gtatcttgat tctagcatca tttggtttag cagcatgtgg
     3361 aaatagcaac aacaccagtc aggcagacac aaaaaaaagc agcacacaaa ctgaaactac
     3421 attgacgata acagatagta atggagacca aatcgaggtg ccaaataatc cagaaaaagt
     3481 cgtcgtattc gacaatggtt ctttagatac gatggatgct cttggtgttg gagataaggt
     3541 agttggagca gctacaagca gccttcctga gtatctttca tcctataaaa aagtagaatc
     3601 agcaggtgga ataaaagaac cagacttaga aaaaattaat cagcttcagc cagatctaat
     3661 catcatttct ggccgacaaa gagattttca aaaagatcta agtcaaattg ctccgaccat
     3721 tttcctttct ttagatgcga aaaatccatg ggaatctttc cagcaaaatg tcactgcttt
     3781 aggggagatc tttggtaagc aagaagaagc taaaactcaa ttagaggaat tatctagtgc
     3841 aatcgatcag acgaaaaaga aagcagaagc tactgacaaa aaagcactag tcacacttgt
     3901 gaatgaaggg caattatcag cctacggatc tggttctaga ttcggtttca tccatgattt
     3961 atttggcttt gaacaagcag atgatcaaat cgaagcatcc actcacggtc aaagtgtttc
     4021 ttatgaatat gtgctggaaa aaaatccgga tatcttattt gtagtagaca gaacaaaagc
     4081 tattggtgga gacgacagca aagatgatat ttctgccaat gaactggtag cacaaacgaa
     4141 tgctggtaaa aatcagcaga tcatctccct tgaaccagat gtctggtatt taagcggggg
     4201 cggtttagaa tcaatgaaac tgatgatcga agatgtgaat caagcattta aatagcataa
     4261 ataacagagg attaaactct catactatgt aacaataatg tttcttacat tcttaaatag
     4321 caagagccta tcctcaaaga agttatcaaa aaccatccgt aaaatcgtat tgatgatttt
     4381 acggatggtt tttatttatt tgagaaatct tttttcaacg tgaattcatt atctacatca
     4441 tacgggttga ttctagaatg gggagtggca aaaaatagtg tgatccattt tttcagcatc
     4501 aagatcgcct cctttgattt gaatcaaagg tacaaagcga aacttagata aaacttaaat
     4561 ttagatattt ttattttgta ccgatctctt ctttaaacga tgttccatct gctgcttctc
     4621 ggcaataagt ccactagact agaaaatatg agaagctatt ttctgtccag cgttcttatt
     4681 actcaaaaca aatcgcagtt gtcacaatct cttctaaacg atgttccatc tgctgcttct
     4741 cggcaataag cccactagac tagaaaatat gagaagctat tttctgtcca gcgttcttat
     4801 tactcaaagc aaatcgcagt tgtcacaatc tcttctaaac aatgttcaat cagctgacct
     4861 tcggtattag ctcaaagcac tgatttcaca acctctattt aggcatgtgt ctcagcaagc
     4921 ggttgatagt tgatgatctg catttttcga taaaaatcgg cgggaagctt actccaccgt
     4981 tttagtaatt gatagaaata actctcttct gctttgattt tatactcgct taatatcaat
     5041 ccaaaactat tcgttttttt tgaagctaat tttttataaa tatccaatgc tttggtttta
     5101 tcttcattga caaagagtgt ttttacttca atataagaac cctcgatatt ttgtgtttct
     5161 tcgataaaat agatgttttt tatatattcc ttcatagtga ttcctccaaa gaagtctttt
     5221 atttgataag tttactctac cgaagagttg ttaataatcc gtgaacaaaa agtaattctt
     5281 tttccaatag ttgttaaagg ttttttattt tttatagtat tttttgttat ttaagaaagg
     5341 aataaggtta aacaaataac aggttgcttt ttgggtcttt ttccgttcaa gaaactgaac
     5401 gaagaaaagg gaaagttgtc tcttttgtga taagagaaat cataataaac gaatgactta
     5461 ctttccaata aattgagaac agtcagaacc agacaaatta gttgcatctg atgaataaag
     5521 tgattattct atgacatgag gtgatacaga tgaaattaga agtgacaaaa gaagcacaag
     5581 aagtattgaa gaataaatta gaagcagacg atcaactttt attagatatc gaaaacggtg
     5641 acggtccatt tgcagaaagc caagtcagtt gccaattgga tacggcattt cgattgatca
     5701 ttgtcaaaaa agatacacaa acagatctaa gtctttattc tgtagtggct gatacaccag
     5761 ttggaccaat caaaatcaaa gacagtgcaa tactttacat ggatgatcca tccacacttg
     5821 ctttagaacc aacttataat agtttacaat taaaaggacc aagcggcttg agaaaaggca
     5881 acttgcaagt tgttcgaaaa gactagaggg ataaaatggg aaaattggcg atcatcagcg
     5941 acctacatgt ggacatcaat aaattcggcg aatcagagct gatgcagctt tggcaagttt
     6001 tgcaaaagca caagatcact cggcttcatc tagccggaga tacggctaat aaagtagacc
     6061 gttgcctagc tgttgtcgaa tttttcgtca ataaaggatt atctacgaca tttcatttcg
     6121 gcaatcacga gttggcagat gtgcccaatg aacagatgat ggaccatttt ccagacccac
     6181 attttttaaa tgaacggtat attgctttaa atgagcagac cgttctttta gggatgaatg
     6241 gctggtacga ctatcagttt tccgaattga aagattacga ggcaatcgta cgaatgaagc
     6301 gtttgtattg gtatgatcgg ttcatccagc gtgggaaaac agatctcgag gtcaatgcag
     6361 aaatgcttgc agctgcaaaa aatttgctag accagctgga agcaaaaaaa cttgaggtga
     6421 ttttatccac tcatttcgtt cctaaacggg catttatcat gtatcaatct gctccttatg
     6481 agcgttggaa caaattaaat gcatttttag gatcagaatc attcggagaa ttacttgacc
     6541 gttattcaaa tatcaaacaa gtagtttttg gccatacgca tcgtcgcttt gaagataaat
     6601 ccatcggtca cacgatttac agctgcagac cttttggtta ttattatgaa tggcagctga
     6661 cccgagattt tgtcttgaaa gaacagttgc tagacagcta tgatcctatg aaattacgtg
     6721 tcctcttgcg tgcccatcac ccagcttttc aggcctatca aacacaacat ttgcaagagg
     6781 aatttgaaca agcgatgaca atcgttccgt attgagacag cattagtaat gtgtaaaaga
     6841 aaataccttg taaaacataa ggataagtaa gagcagtaga tccatttatc gtggatatgc
     6901 tgcttttttt gcggaaaata atcagcgaat gtttatttga tcggatgatt tgtaactcgc
     6961 agagtactag atgcaagcgt gtattctttt tttgaacgat aatcacaaaa aaaaatataa
     7021 tatacatttt ttatttaatt ataattaata ttgattgaag tctaggcagt caagtcgaga
     7081 gt
//
LOCUS       DAPBAF010000084         7020 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.088, whole genome shotgun sequence.
ACCESSION   DAPBAF010000084 DAPBAF010000000
VERSION     DAPBAF010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7020)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7020)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7020
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.088"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(151..609)
                     /locus_tag="RD451_002696"
     CDS             complement(151..609)
                     /locus_tag="RD451_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDT7567897.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
     gene            complement(622..1953)
                     /locus_tag="RD451_002697"
     CDS             complement(622..1953)
                     /locus_tag="RD451_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HDT7567898.1"
                     /translation="MMMKKQIITIAGGGSTYTPGIVQAILNNEKRLPLSEIRLYDIDE
                     ERNMDMYLIVKFMLKRKGFSNIRIRATDDPKLAFTGCDFVFSQIRVGGLEMREKDEKI
                     PLKHGLVGQETCGLGGFAYGMRSIKGLLEIVDHIQDYAPKAWILNYTNPESIVSEAVR
                     RKYPNVKMINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIYDKELQREI
                     MPEIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITKNFPSNIPNNYLEYYLYPDMVV
                     EHTDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVLNFNFGEHGQYIVDIAISLLND
                     DRRRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVEPITLRKPISDFHKGLMEAQVAV
                     EKLLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILDEMIKVNKKYWPALK"
     gene            complement(1964..3406)
                     /locus_tag="RD451_002698"
     CDS             complement(1964..3406)
                     /locus_tag="RD451_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDT7567899.1"
                     /translation="MRIFNRGGIKMNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADD
                     MLNIPVIGAAGNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMD
                     PEVNMGIFGGIISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAVFLG
                     FIWPLIQIGIDNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSP
                     SKEVFRGEMTRFINGDPQAGLFLSVFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMG
                     SGAGTSFIANITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVD
                     YLINFRIATNAILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEET
                     ELGLASKNYEYMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISG
                     IIKPTEKNYQIIIGLEVTYVMAEFNKLLEE"
     gene            complement(3393..4157)
                     /locus_tag="RD451_002699"
     CDS             complement(3393..4157)
                     /locus_tag="RD451_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HDT7567900.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            complement(4261..5136)
                     /locus_tag="RD451_002700"
     CDS             complement(4261..5136)
                     /locus_tag="RD451_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDT7567901.1"
                     /translation="MKESASCFVLSYRGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAVEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            complement(5391..5475)
                     /locus_tag="RD451_002701"
     tRNA            complement(5391..5475)
                     /locus_tag="RD451_002701"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5439..5441),aa:Leu,seq:caa)
     gene            complement(5493..5564)
                     /locus_tag="RD451_002702"
     tRNA            complement(5493..5564)
                     /locus_tag="RD451_002702"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5530..5532),aa:Gln,seq:ttg)
     gene            complement(5574..5646)
                     /locus_tag="RD451_002703"
     tRNA            complement(5574..5646)
                     /locus_tag="RD451_002703"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5611..5613),aa:His,seq:gtg)
     gene            complement(5708..5792)
                     /locus_tag="RD451_002704"
     tRNA            complement(5708..5792)
                     /locus_tag="RD451_002704"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5756..5758),aa:Leu,seq:caa)
     gene            complement(5813..5883)
                     /locus_tag="RD451_002705"
     tRNA            complement(5813..5883)
                     /locus_tag="RD451_002705"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5849..5851),aa:Cys,seq:gca)
     gene            complement(5929..6000)
                     /locus_tag="RD451_002706"
     tRNA            complement(5929..6000)
                     /locus_tag="RD451_002706"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5966..5968),aa:Gln,seq:ttg)
     gene            complement(6012..6084)
                     /locus_tag="RD451_002707"
     tRNA            complement(6012..6084)
                     /locus_tag="RD451_002707"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6049..6051),aa:His,seq:gtg)
     gene            complement(6087..6160)
                     /locus_tag="RD451_002708"
     tRNA            complement(6087..6160)
                     /locus_tag="RD451_002708"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6126..6128),aa:Trp,seq:cca)
     gene            complement(6167..6247)
                     /locus_tag="RD451_002709"
     tRNA            complement(6167..6247)
                     /locus_tag="RD451_002709"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6211..6213),aa:Tyr,seq:gta)
     gene            complement(6249..6324)
                     /locus_tag="RD451_002710"
     tRNA            complement(6249..6324)
                     /locus_tag="RD451_002710"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6289..6291),aa:Phe,seq:gaa)
     gene            complement(6360..6432)
                     /locus_tag="RD451_002711"
     tRNA            complement(6360..6432)
                     /locus_tag="RD451_002711"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6397..6399),aa:Asp,seq:gtc)
     gene            complement(6442..6514)
                     /locus_tag="RD451_002712"
     tRNA            complement(6442..6514)
                     /locus_tag="RD451_002712"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6479..6481),aa:Val,seq:tac)
     gene            complement(6530..6601)
                     /locus_tag="RD451_002713"
     tRNA            complement(6530..6601)
                     /locus_tag="RD451_002713"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6566..6568),aa:Glu,seq:ttc)
     gene            complement(6616..6705)
                     /locus_tag="RD451_002714"
     tRNA            complement(6616..6705)
                     /locus_tag="RD451_002714"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6669..6671),aa:Ser,seq:gga)
     gene            complement(6745..6818)
                     /locus_tag="RD451_002715"
     tRNA            complement(6745..6818)
                     /locus_tag="RD451_002715"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6782..6784),aa:Asn,seq:gtt)
     gene            complement(6828..6943)
                     /gene="rrf"
                     /locus_tag="RD451_002716"
     rRNA            complement(6828..6943)
                     /gene="rrf"
                     /locus_tag="RD451_002716"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         2114 a         1551 c         1149 g         2206 t
ORIGIN      
        1 ataagttttc taaatcatag gagcaacaaa aaaattcgat aattaacaaa aatcaaaatg
       61 attaaatcta gtgattgaaa catatcattt caaaaaaatt ttgtaaattc acccataaat
      121 atcaccctat ttaacttttt tcatcgtaca ctaaaattca aaacaactat ctttaatctt
      181 tacttcttgg ttttgtttta ataaatttcc ttcaaaaatg cctggagaaa ctacaatgat
      241 caccgtatct ttttgtgctt gctccaactt cttcaaatct ataatagcta acagtgtccc
      301 ttcttttacc tcctggttac tttcaacccg tatctgaaac ggacttcctt cgagttcaac
      361 tgtatctaaa cccatatgga tcagtatttt tctgccagat tcactttcga tcgttatggc
      421 atgtcgggta ggaaatatat tatcgattat tcctttaact ggcgcatgga tatatccatc
      481 atgattcgtt atagcgtatc caactcctat catttttgaa gaaaagacct cgtcttttac
      541 tgctgttaat ggaataattt gaccactagc tacagctttt agaatgtttc ttgttttaaa
      601 gaaatgcact ttttatcacc tctactttaa tgctggccaa tattttttgt ttactttgat
      661 catttcatct agtatttttt ttgcgactct ggcatttggt acggtttgat tcaatgtaaa
      721 tgcttgtaaa gctttttgat aagaaccttc aaagtaagca tctactagta acttctctac
      781 tgcaacttgt gcctccatca atcctttatg aaaatcactg attggttttc ttagtgtaat
      841 tggctccaca ccagttgcac caacatatgc cggtatttca acaactgcat ctgaccgtag
      901 attcggaatc gccccttgat taggaacgat tagcataaag cgacgacgat catcattcaa
      961 caaggaaata gctatatcga cgatatattg tccatgctcc ccaaaattaa agttcaatac
     1021 ttcttccaca ataccgcggc gtattttatc agccatttct ttggtatttt tctctcgtcc
     1081 atccatgacc atattagcac gtgtatactc tttgtcagta tgctcaacga ccatatcagg
     1141 atataagtaa tactctaagt aattattcgg gatattactt ggaaaatttt tcgtgatgac
     1201 tgacatcatt tgaaaggttt tttgccaagt tttatctcct atattaaaat cggcgacttg
     1261 catttctttt gttattagtt tttcaataat ctctggcata atttctcgtt gcaattcttt
     1321 atcataaatc gatgtatacc agccaaagtg gtttaaacca taatacgtaa cgatccaatt
     1381 cttacgatca taaccgtaat tcactgcaat cgtttcttca attgaaatag tcatatcaca
     1441 ggcattaatc atttttacat tcggatattt acgacgaaca gcttcagaaa cgatcgactc
     1501 tggatttgta taattcaaaa tccatgcttt gggggcatag tcttgtatat gatcgacaat
     1561 ttccaataaa cctttgattg agcgcatccc ataagcaaat cctccgagtc cacacgtttc
     1621 ttgtcctact aatccatgtt taagtggaat cttttcgtcc ttttctcgca tctccaatcc
     1681 tccaacacga atttgtgaga aaacaaaatc gcatcctgta aaagcaagct ttggatcatc
     1741 cgttgcacga atgcgaatat ttgaaaaacc ttttcttttc agcataaatt taacaatcaa
     1801 gtacatatcc atatttcttt cttcatcaat atcatataaa cgtatttcag ataatggcaa
     1861 ccgtttttca ttgttcaaaa tggcttgaac gattcctggt gtatacgtac tcccgcctcc
     1921 agctatagtg ataatctgtt ttttcatcat catcttttcc tttctattct tctaataatt
     1981 tattgaattc tgccataaca taagtcactt ctaagccgat gataatttga taattttttt
     2041 cagttggttt aatgatcccg cttatcccta attgcttgat tcgctgttcc tcgaccatgg
     2101 tgggatccac tacctctacc cgtaggcgtg tattacaact atagacatcc aggatattgg
     2161 cttttcctcc aaacgcttgt agcatttttg ttgccatata ttcataattt ttacttgcta
     2221 accctaactc tgtttcttct aaggttactt cattgccaaa ctctgcctta gcttcacgtc
     2281 ctaatgtctg aatgtttctc ttattgatca aataataaaa agtaacgtaa tacaaggcaa
     2341 aaaagaaaat tccgattgga agaatcaaaa tagcattggt agcgattcga aaattgatga
     2401 gataatcaac aatacatgct ccgaatgtaa aaccaattcg tatattgaat aagtaacaga
     2461 caatccctgc taaaccggca aaaagtgcat ggatcacgta caacatagga gaaagaaaca
     2521 tgaaactaaa ttcaacaggc tcagtgatat ttgcaataaa tgaagttcct gcaccgcttc
     2581 ccatgattcc tttgaccatc tctttatttt ctttataagc tgctttatag atagctagac
     2641 atatagctgg tataccaaac atcattacta caaaaaaaac tgataaaaac agtccagcct
     2701 gaggatctcc gttgataaag cgtgtcatct ctcctctgaa aacttccttg ctaggagatg
     2761 tatagcttcc taaatcgtaa taaatatacg tattcaacac atggtgcagt ccaaagggga
     2821 tcagcaaacg attcaaaaac ataaatatcc ccacacctaa tgctcccata tcaacgagca
     2881 gttttgcaaa attatcaatc ccaatttgga tgagcggcca gataaagccc aaaaaaacag
     2941 ctgcgattgt ttgtagaatc atcaccatag tcaatgggaa tttttcgccc gcaaaataag
     3001 aaaaaactac tggtaatttt tgttctttaa agcgattata cgtccatgcc gctactaaac
     3061 cggaaataat tccaccaaaa atccccatat tcacttctgg gtccataatt tctaagcctt
     3121 ttttcaaggt agcaatcgct aaaaaaccag taagtgcagg tattcctttg tccttatttt
     3181 tgacaaaacc gattgcaact cctatagcaa ataagatatc caagtttcca aaaacggcat
     3241 ttccagctgc accaattact gggatgttca gcatatcgtc agctgataaa cgcatgatca
     3301 atcccgctaa tggcatcgct gcaactggaa gtagcatcgc tcttccaagc ttctgcacat
     3361 ttgatttaac attcattttt attcctcctc tattaaatat cctcatatgt tactaactca
     3421 atcaaaggat catttttcac tttttgagca aatgctgaat gaattaaaaa ttcgacttgg
     3481 tgggtacgag gatacacaaa acttgaacca tttaacaatt cctgatccaa atacgctgcg
     3541 tgacacatga cttcgatcgt tttatcttct ctcaatatca tgagtaaact tgccaaatat
     3601 tcttccacac tcgtattgat ttgtcgtttt ttttcatcag tttctcctac gacatcgaaa
     3661 caaggctcaa aataatcgac atgacgaact tcatcttttc gttcaaagtt gctccgaacc
     3721 ggcaaatcat atttttttgc taatgtaaca actacctcct gattttcatc caaagtatga
     3781 gtatgatgat gactgtctaa atgagttggt atgatccccg catgataaat tttttgaatc
     3841 tgagcattcc attcctgata cagttgatct ttgtcaatgt taaatggatg ctgataataa
     3901 gataaggatc tgaactctcc gctttcgata agagtatcga cagttttgag gagtggtttg
     3961 ccacacgtca atgttaaatg gactcctaca cctagcctag gcatttcctt tcttagtttc
     4021 acagcatgct cgaaacccgg catatttgcc atcaatgtag ttgatgtcaa aattcctcgc
     4081 tgataagcat ccataatccc ataattcaca ccatggctat agccaaaatc atccgaatta
     4141 aaaatcactt ttcccatttc attctccttc ttttttctac taaaataggc gcaaccaaat
     4201 aatcatagtc catttactat gtgtcatttg gttgcgccta tagatagtta cgcccttatt
     4261 ttaatagatt cttgctagat gaattgccaa atagatgatt tcattttctt gaatggcaag
     4321 ttgaaattgc tgttcgatga tatctttaat ctttagtgct gtacaatacg ctttgctatg
     4381 tttaaatgtt tcagtaaaaa aaccaatatt ttctactggc gtttcttcct gataaatcaa
     4441 gcgtttaacc aggaatttga tatgaaccat taagcgatga taagtcagtg attctttatc
     4501 ataaacgttt gaataggatt tttctagatg ggacaaaatc gtggtcgtca tttctactat
     4561 ttttaagctc tttaaactat taggctctcc tagctcagca ttaatgatat gcatagtgat
     4621 gaatcctact tcatttgacc ctaactcggt ttgatatcga tgattgattc gctcgaccac
     4681 ttctactgct atatcatatt catttggata aaggaatctc atttctggca acataattgc
     4741 tgtgacatct ctatcttctc tttttcgttg aatagcaaaa taaatatgat ctgtcaatgt
     4801 aatatagata tttgaatcta atggagagga gatcctagct gttatcagtt caatcacttc
     4861 ttccgcaaaa tccataaatt cgattggaat ctgcgagact atctcactga atcgtttgat
     4921 cttttcttta gaatctaata caaataattt gtcagcatcc tcaacatcaa atggcttact
     4981 cactttagca gaaaagccaa tccctttccc catcgcaatt ttttctattc catcgtcatc
     5041 gatcaataca gcattatgat tcagcttttt catcacatac accgttaatt cacctcctct
     5101 atatgataaa acaaaacaac ttgcagactc cttcatacat atttttgtct ccaaacaatt
     5161 tttaaagaca aaaaacgacc taagaaagaa ccctttctta ggtcgtgcct aattgaatag
     5221 tagcacccta cataatttac aaaaatagtt taacacataa taaaagcgtt atcaatatct
     5281 tttttactcg ttttatgata atacttgtat cgaattgatt tggaggtaat tacataaaaa
     5341 caaaaaaaat atagcaactc tctataagaa agttgctata ttgataatta taccggcggc
     5401 cggggtcgaa ccggcacgtc ctcaacggac actggatttt gagtccagcg cgtctgccaa
     5461 ttccgccacg ccggcaaatt taaaaataat aactggggta gctggattcg aaccaacgca
     5521 tgagggagtc aaagtccctt gccttaccgc ttggctatac cccaagaata aagggcgaat
     5581 gatgggaatc gaacccacga atgccggagc cacaatccgg tgcgttaacc acttcgccac
     5641 attcgccatc ataaaagatg ttatttaatt tctcaataaa aaactaagat gaagacatct
     5701 tagtcaatac cggcggccgg ggtcgaaccg gcacgccctc aacgggcact ggattttgag
     5761 tccagcgcgt ctgccaattc cgccacgccg gcaagttgat ttattagtac taaggcggta
     5821 accggatttg aaccggtgat gaaggttttg cagacctctg ccttaccact tggctatacc
     5881 gccattatac tattatcaat ctataaaata aagaataaat tatagaaact ggggtagctg
     5941 gattcgaacc aacgcatgag ggagtcaaag tcccttgcct taccgcttgg ctatacccca
     6001 agaataaaaa gggcgaatga tgggaatcga acccacgaat gccggagcca caatccggtg
     6061 cgttaaccac ttcgccacat tcgccatggc aggggcagca ggaattgaac ccacactaac
     6121 ggttttggag accgctgttc tacctttaaa ctatgcccct ataaaatgga ggagagtgga
     6181 ttcgaaccac tgaaccctaa ggaacggatt tacagtccgt cgcgtttagc cacttcgcta
     6241 ctcctccatg gtggcgcggg acagaatcga actgccgaca cacggagctt caatccgttg
     6301 ctctaccaac tgagctaccg cgccatattt taaaattatt aattgaataa caagaacgac
     6361 ggttccgacg ggaatcgaac ccgcgatctc ctgcgtgaca ggcaggcatg ttaaccccta
     6421 caccacggaa ccagttcatt atggaggtta acgggatcga accgctgacc ctctgcttgt
     6481 aaggcagatg ctctcccagc tgagctaaac ctccaacatt caattaaaat gacccgtacg
     6541 ggattcgaac ccgtgttacc gccgtgaaag ggcggtgtct taaccgcttg accaacgggc
     6601 caggtaaatt tgctacggag agtaagggat tcgaaccctt gagacagttt ggcaccatct
     6661 acatgatttc caatcatgct ccttcggcct ctcggacaac tctccagagt gaaagaagct
     6721 caatactctt tctcaaaatg agaactccgg cagtaggact cgaacctacg acatcatgat
     6781 taacagtcat gcgctactac caactgagct atgccggaat aacatcagcg tggcgacgtc
     6841 ctactctcac aaggggcaac ccctcactac aatcggcgct aagaagctta acttctgtgt
     6901 tcggcatggt tacaggtgta tccttctcgc tatcgccacc acactgtggt gttatctttt
     6961 attgagtaaa ttttgttcac tcaaaactgg atttgaagtc acataagttt ttttccgagt
//
LOCUS       DAPBAF010000085         6688 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.089, whole genome shotgun sequence.
ACCESSION   DAPBAF010000085 DAPBAF010000000
VERSION     DAPBAF010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6688)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6688)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6688
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.089"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(<1..115)
                     /locus_tag="RD451_002717"
     CDS             complement(<1..115)
                     /locus_tag="RD451_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017370594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HDT7567902.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDR"
     gene            246..698
                     /locus_tag="RD451_002718"
     CDS             246..698
                     /locus_tag="RD451_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567903.1"
                     /translation="MKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNK
                     KMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSEL
                     VSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     gene            712..1401
                     /locus_tag="RD451_002719"
     CDS             712..1401
                     /locus_tag="RD451_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567904.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            1526..3877
                     /locus_tag="RD451_002720"
     CDS             1526..3877
                     /locus_tag="RD451_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1906 domain-containing protein"
                     /protein_id="HDT7567905.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
     gene            3957..4352
                     /locus_tag="RD451_002721"
     CDS             3957..4352
                     /locus_tag="RD451_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567906.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
     gene            4677..5294
                     /locus_tag="RD451_002722"
     CDS             4677..5294
                     /locus_tag="RD451_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDT7567907.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
     gene            5335..5634
                     /locus_tag="RD451_002723"
     CDS             5335..5634
                     /locus_tag="RD451_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BRCT domain-containing protein"
                     /protein_id="HDT7567908.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFL
                     VCGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
     gene            5668..5835
                     /locus_tag="RD451_002724"
     CDS             5668..5835
                     /locus_tag="RD451_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDT7567909.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKNYFYCP
                     KCHRRYGVHGT"
     gene            complement(5880..6485)
                     /locus_tag="RD451_002725"
     CDS             complement(5880..6485)
                     /locus_tag="RD451_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDT7567910.1"
                     /translation="MGKIGYIRVSSQDQNLDRQLAMMEGLNIDKLFQEKASGKDTERP
                     EFQKLLNYIREGDCVIVTSLDRLGRDYEDIKNTVAFMKQKKVALKILDAQFLDFNTGN
                     ELLDTAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAQKAGRYKGRPIEYSINSTDPQ
                     KRLVFKTVVDMLKQGIPVAEIAKENGISRPTIYKIKKANDL"
BASE COUNT         2304 a          935 c         1303 g         2146 t
ORIGIN      
        1 cacgatcata taagatttct tgaacttcac gatagctaag gttataacga agatagtagc
       61 ccacggctac aataatcaca tcctgctgaa attgctttcc tttaaaatga ttcatcgtta
      121 ttcctcctgc tatctttttc tattattcta tcttatttga tagtagattt aaaactttgc
      181 aacagaacca attatcttat cgtagatata tattataaat ttaataagaa agcgaggtga
      241 gaatcgtgaa aaaaacgata ctaagtattt tttcagtatt tacaatatta attgggggct
      301 attttctttt gaatttagat tctgttaatt caaacgctca aataaaagat caaagagtag
      361 ctgaacataa taataaaaaa atgagtttga ccaaaaatat ctattctatg tcagatgaag
      421 aattgtataa agaatttggt gatttatccg gggaacagtt agaagaaagt attccaggaa
      481 ttagtgactc agataaaatt gttgtcttgt ctgctggtgg gcaattaatg ggagatggca
      541 aatccgaatt agttagttat aaacaaaatc acagacagtt tattgatgtt aatactgatt
      601 ccaacgctat ttcgattaag gatctaaaag agcttttaaa tagtaaaaga aatgaattaa
      661 agcagataaa agaaactaat tcagtggaat tagagtaaag gaagattcat tatgaaaaag
      721 atttttggtg tttctgttgg gctacttatg atgttaacat ttggaaatgc agtatatgct
      781 gctgagaaag aagttatttc agatccagag cagtacgcct cacgatactt tgctgatttt
      841 gaagaagaag ataaagtact tgcattgcca gaaggtggtt ttttaaaagg ggaagctaaa
      901 attgtatcta tggataatcc agatataatt caaggttcat ataattcaga aactgatcct
      961 gcttcagttt cagtgacaga agcaaaaaaa attgttgctg aaaaattcaa aaatgatatt
     1021 gaaactactc caattatgcc tcgaggagca tttccacccg atgttggtac tagcggacac
     1081 cttcttgtac tagcaggagg aggaagctat aaatcacagc catttagtgg tgcgggatgg
     1141 cgttttggag gtatgggtgt aaaaccagct gatggtacag gcaacttttt acgttggaaa
     1201 tcctacattg acgatggaag agtaggaaat gtaaatcaag ccaacgcaac taaatctggt
     1261 tctattcaag gaatggcatt gtatgctcgt gaaggattca aatactttgc accaaacggg
     1321 cctggttgga caatgaatat aggtatttat tacacttata atcctgttgc aggtacgtat
     1381 tatgttgttc aaaatattta ataaaacagc acaaagagat ttctttgtgc tgttttatta
     1441 tttttagttg ttgacaaaca ctaaaatata aaatataatc aacacataaa cgaacgtatg
     1501 ttcggcaaga aagcagggga tttttatgga tgagatggtt ttaagtactc agaaatggct
     1561 aaacaagaaa tacagtaatg ttacagggtt tgataaggtt ccagaaaatg ggcgaacagg
     1621 gtggcctaca atctatggac ttattgaagg actacaagta gaacttggta ttactaatct
     1681 agtagctaat tttggaccta ccactgaaaa aatgtacgat aatcaggtta ctcctaaatg
     1741 gggcaaaaat ctacctaaaa atattgtatt tcttattcaa ggtgcctttt ggtgtaaggg
     1801 gattaatcca ggtggcttcg atggggtata tactccatat ttagatactg ctgtaaaaga
     1861 gttgcagact gatgcagggt ttaatggaag cgctgtaact ggagttttgg atgcgaaatg
     1921 ggccaaagcg ttatttgata tgagtgcttt tgttcttgtt cccggcggag atagtaaaat
     1981 tagaaaaatg cagcaatggt taaatgtaaa ttatttagaa tacacgggaa taatgccttg
     2041 tgatggtatt tatcaaagaa attcaaatca agcattaatt tttgcattac aagctgaact
     2101 aggatattct cccagtgaag caacagggtc ttatggtaat gggacaacta gtaaaactta
     2161 tcctgtgtct gaaggtaact cgggaaacta tgtaagaata attcaatatg gattatatgt
     2221 taatggttat tttgaagacg gtacattcga tggtattttc actaaatata tgggtttaga
     2281 agtactggca ttccgaaaat ttatggtatt gcctgaatat actgaaatag cagatgttgt
     2341 tgtaataaaa ggactattgt ctagcgctgg agatattaga agatctgcag atggcgcaga
     2401 tacttctacg caattaacta gatctcaaat ccaaacattg gttgataatg atataaaaat
     2461 agttggtaga tatcttactg gtactgttgg aattggaaaa gatgaacgaa ataagtatct
     2521 aactacagag gaattgaata atattttttc taaaaattta tctgtgtttc ctatctatca
     2581 agatggaggt gcagcattag cttattttac ttatgatcgt ggcttatcag atggtaagaa
     2641 ggctatagat gcagcaaaaa atctaaatat accattaaca acagttattt attttgctgt
     2701 tgatctagac atgttagggg aagaaattct tgcatatgct ggagaatatt ttaagggggt
     2761 atctgctgta atgtcatata gcgggtatca aacgggtgtt tacggaacaa gaaatgtttg
     2821 ttctcaaata atcaataacg ggtatgcttc gtttgcattt gtttcagata tgtcgactgg
     2881 ttatagtggg aatttaggtt ttcctatgcc tagacaatgg tcttttgatc aatttgttga
     2941 atttaccata ggaagtggca acggagctgt tggtatcgat ttaatcgcta catcgggtag
     3001 agatagcgga tttaatgagt tatcaaatga tactaataat gataattaca ttgccaaata
     3061 caatcagaag gttataaatc agatggtacg tgcgtatcaa tatctatcac aagctggtct
     3121 tgataatcct tggaaccctc atttgacatt ttatagatat gtaaattatt ctggtttgtc
     3181 atgggacatc atttcttctc ctgtaacaga gcatgataga aaaatttatg atgaatatag
     3241 gaataaatta actaatagcg agggcctgta taattatttt atagatccta atactggttc
     3301 aataataggt ttgcctcact taattgtgac gttacaatca cagatgtttc tagccgacac
     3361 aatcaatgat agtgtttctg actttgcagg ttggttagga gatttaatga cttgctgggg
     3421 tgaagttaag aaattaggaa tacaaatgga gcaaggtgta tttgcattag taggtacggc
     3481 tgcaggtgga acatttagtc tagaagattt ataccaagat gttgacgcgg taaatgttta
     3541 taccttagca aaaagaaatt ctgattcaac agctttatcg gctttaaaaa cgtactattg
     3601 tgataagggt gctattgata gatttaatca atttgttaag aacagatttg gttcttcaga
     3661 taaaatcgct tcagtaacaa atagtttatt agaaaatgac gaaacagttg atatcttagg
     3721 tgtagggata atttcatttt tcattgataa aatagttaat aattcacttg ggacagattt
     3781 tacttatctt gattttattg gagatgaggg gaaagttgca aatggatttt ctgaaaaaat
     3841 tattcaattt caagaaaata gaagtaaact taattaagaa tcgtttacta tttaaacagt
     3901 gtccttttcc tttttaaata tatacgataa aataagtata tgaattgtaa aaggacatga
     3961 tgattatgga agaaatagaa tggaataatc tgactcaaaa taataaaaat aattctggat
     4021 gtggaattat ctttatgttt gttatagttt tgggaatagt agtactttta ataactgtca
     4081 agatagtaga ttactttgcg aatactcctg aagaacaaat acagagaaaa cttcctgagt
     4141 ttgaaagagt accaccttat gatccaagag ataattcatt tcaagtaaaa aaattaaaag
     4201 agtctccaaa tgaaatgtgg tttgaagtta cagttgaatc aagcgacttc aaagaaaaaa
     4261 agaaagaata caattatatt gtaaaggcaa aagtatcaaa aagatttatt tttaacccta
     4321 aattagaaat atatagtgtt gtaatagaat aatagtgtta aaaaaattgt aaaagttaaa
     4381 gaagtcaaat tctgatgtga aaaataaaat ataccatgga agacataaaa gaaaaactgg
     4441 ataactagtt tatttaatgg cagaccgtta aggcctgcca tttttatgta ttttagcgga
     4501 ataaatataa tcatgcggga gtgtaaactt actgtttcaa aaagtatact ttttgacatg
     4561 ccttgatttt ctttgtttat gtatggcata ataaccacat aatacaattt gaaacgtttc
     4621 tgatttaatc tgattgtttt gaaacaattt tagtgaaaaa agggtagata aaaacgatga
     4681 gaaaattttt ttatatccgg gtcagtagtt atgatcaatc gatcgaacga caactgattt
     4741 ccgcgaagga attaggaatc cctgaagaat atatatttgt agaaaaagcc agcggcaaag
     4801 attttaaacg ccctgaatat caattaatga aacggatgtt tcgaaaagga gatttactct
     4861 atctacaatc attagataga ctaggcagaa ataaacaaat gattttagaa gaatggcgag
     4921 aattaactaa ggaaaagcag attgatattt ctgtgttaga catgcctctg ttagatactg
     4981 ctagttacaa gcaactagat gggttagaga cgcttatctc tgacttaatt ctgcaattac
     5041 tcagctatat ggccgaagac gagcggaaac gaattaatag ccggcaaaga gaaggcgtag
     5101 aagctgcgaa acaaaagggt gtaaaattcg gcagaaagaa aattgcttta cctcctgaat
     5161 ttcctgcgat ctattctgac tggaaagcag gaaagataac tgcagtctat gctatggatc
     5221 aattgggcat gaaacgaaat accttttatc gacgggtgaa agaatatgaa cataccttgc
     5281 accacttttc ttgatagata taacagctat tagacgggaa gggagagttt gaaaatggac
     5341 ttaacgaatc aaagggtcgt ttttactgga acgctgcagc aaatgacacg aacccaagcc
     5401 atcggtttgg ttcactcttt aaacggccat tgtcaatcaa gtgttacttc aaaaacaaat
     5461 ttcctggttt gtggtcagta ttctaagtcg ttgtttgatg attctctcta tacaaaaaag
     5521 gaacaaaccg cgcgggactt gattgcgtta ggtcatgaga ttaccatttt atcagaagtc
     5581 gaattttatg cgttaattag tcaacagttg aaagaatggc aacggtattt ataatcgtta
     5641 gtaaaattta caaggaggaa aatttttatg aagcgaaaat cttatgatcg ttggggcatt
     5701 gaaataacta gttttaatcg aaatattgct tttcacgtgg agtgtgactg tggggaatta
     5761 gcaaaaagtg tttatcaaaa aaattacttt tactgtccta aatgccatcg ccgatacggg
     5821 gtacatggaa catagaaacg aaatagtgcg gtagaaaagc gaatgaatgt agtatatttc
     5881 tacaaatcat tcgctttctt tattttataa atagttggtc gagagatccc gttttctttt
     5941 gcaatctctg caactggaat gccttgcttt aacatgtcca ccacggtttt aaaaactaag
     6001 cgtttttgcg gatctgttga gttaatagaa tactcgattg gtcgtccctt atatcggccg
     6061 gctttttgag ccaataatac tccttgccgc tgacgttcac gaattttctc acgctcgttt
     6121 tgtgcaatat aacttagcag tgataaaaac atatcgaaca tagcggtatc caggagttca
     6181 tttccagtat taaaatctaa aaactgtgca tctaatattt ttaacgctac ttttttctgt
     6241 ttcataaaag caactgtatt ttttatatct tcataatctc ttcctaaacg atctagtgat
     6301 gtaacgatga cgcaatcacc ttcacggata taatttagta atttttgaaa ctcaggacgc
     6361 tcagtatctt taccactggc tttttcttgg aataatttat caatgttaag tccttccatc
     6421 attgccaatt gtcgatccaa attttgatct tgtgaagata ctcgaatata gccaattttt
     6481 cccataaaaa actccttttt aaaagtgata taatttacat gtaaaattta cttgtagttt
     6541 tactgctatc atagcatttt taaaaataaa ttttatgtag acttaaaatt tacttcatgg
     6601 agggtttaaa tggatgaaat caaaagtaac aaaaaagcat ttggcattta tttaggagaa
     6661 cctagtacag aacaattaaa ccaatttt
//
LOCUS       DAPBAF010000086         6386 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.090, whole genome shotgun sequence.
ACCESSION   DAPBAF010000086 DAPBAF010000000
VERSION     DAPBAF010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6386)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6386)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6386
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.090"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(45..779)
                     /locus_tag="RD451_002726"
     CDS             complement(45..779)
                     /locus_tag="RD451_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HDT7567911.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1106..1516
                     /locus_tag="RD451_002727"
     CDS             1106..1516
                     /locus_tag="RD451_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HDT7567912.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1509..2210
                     /locus_tag="RD451_002728"
     CDS             1509..2210
                     /locus_tag="RD451_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HDT7567913.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2210..3796
                     /locus_tag="RD451_002729"
     CDS             2210..3796
                     /locus_tag="RD451_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDT7567914.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            3815..4036
                     /locus_tag="RD451_002730"
     CDS             3815..4036
                     /locus_tag="RD451_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HDT7567915.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            4033..4794
                     /locus_tag="RD451_002731"
     CDS             4033..4794
                     /locus_tag="RD451_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HDT7567916.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            5174..5683
                     /locus_tag="RD451_002732"
     CDS             5174..5683
                     /locus_tag="RD451_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HDT7567917.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(5758..6297)
                     /locus_tag="RD451_002733"
     CDS             complement(5758..6297)
                     /locus_tag="RD451_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HDT7567918.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
BASE COUNT         1991 a         1170 c         1296 g         1929 t
ORIGIN      
        1 ttggtacgca atcgctgtac caagtttttt tatttagctt ttgattaagc cataaataat
       61 aatttatata agaatactgc tacgacacca gcacagatag gtgctacaac tggtacccat
      121 gcatatcccc attgagaaga acctttatgt ttcaatggaa gaagtgcgtg tacaagacgt
      181 ggagcaaagt cgcgggctgg gtttagtcca ggacctgtag gaccaccaag tgaagcaact
      241 aatgtccata caaggaaacc aagtgctaag tgagctgtac caagattatc ttggaagaat
      301 ggtgcttttg taatacctag ggcaccaaag aataaaacga atgaaccaaa gaattcattg
      361 acgaaaccat tgaatttaga accaacgctg ttgattgttg agaatgtacc taacacatgg
      421 tttacgtctt ctgtttggtc gtagtaaggt ttgtaacaag ctactacgat caattgtcca
      481 atcgctgcac caatcaattg tgcaatgata taaggaacaa cttcagccca agggaataga
      541 ccattagatg ctaaagcaat tgtaaatgct gggttgatgt ggttaccgct gattccacca
      601 aaaatcattg ctggcatcat aaccccgaat ccatacccga cagcaatcag catccagtca
      661 ctgccatatc cttttgtacc ttttaaatct acgtttgcta cagcaccgtt acctagaacg
      721 attagtaatg ctgtaccaat catttccgcc gcaagacggg tcattagtga gtaatccata
      781 aatacctcca aaagttataa aaatgcaaaa aaaaaagaaa catcaacacg aaaagcatcg
      841 gtgcagtgtt tcgtgtcgga aggatttctg cagtcttaac aaatgtgaat aaaaaaatga
      901 attccattac ttataagaaa ccagaccaac agtaaaactc caactctttt taaaagttct
      961 ccacaaatca ccaagcttaa ctataaatat accaaaaaaa aaacgttttt tttctcaaaa
     1021 attgtatctt agaaacagca tgttttgaaa ctttcagaaa aggtttgtta gtaaaatgaa
     1081 agctatacgt aaggagtgtt gtttgatgaa attttttcaa gagtttttca ttattatttt
     1141 cttttctgta ttaggagaag gcatacggat ttttgctcat ttacctattc ctggaagtat
     1201 cttaggtatt ctttttttat ttttagcatt tgaaatgcat cttgttgatc ctgaaaaaat
     1261 cggagcaact ggtgattttt tattgaataa tctagccatt ttatttgttc ctgctggtgt
     1321 aggtttattg gaatattttg atgatattgc ttcgatatgg cctgttttac tgggagcagt
     1381 cgtcgtgtgt tccatcgtca cgatggttgc agcgggaaaa acggcagaag gtgtagaagc
     1441 tttgctgggc tatgtccgta agaaaaaagc agaaagggta tctgtaaacg aaatggagga
     1501 gaatcaaatt gactgagttt tttgtgaatc cattatttgg cttaagtttg actttaggag
     1561 tgtacgtatt atctgacaaa tttttgcgga aatataaact gcctgttttg aatcctctcg
     1621 tattatcgat tgttgttatt atcttatttt tgcatttttc tgggatcagc tataaagact
     1681 ataatatcgg gggcaatttt ttgactatgc tgattactcc tgcgacagtg gcacttgcca
     1741 tccctcttta taaaaacttc cgtttactga aagagaattt ttatcctgta atggctgcga
     1801 ttttagcagg aatagtcgca aattgcttgg ttagtgtagg gttcggttac ttcttctctc
     1861 ttcataaaga gatggtgatc tcattactac ctaaatctgt aacgacggct atttctgtcg
     1921 atttatctca tacgatgggc ggggtgaatg ccgtgacact tgctattgtt gtctctacag
     1981 gtatttttgg ttcgctgatc gccactcata ttttccgcct attcaagatc gaaagtccag
     2041 ttgctcgcgg tgtggcgtta ggaagtactt ctcatgctat tggtacagca aaagcaatcg
     2101 agattggtga aatagaagga atcatttccg gacttgcgat atgcgtcaac ggaatattga
     2161 ccgttttatt gctaccgtta ttctttcagc cttttgctgg cttgttttga tgcgaaaacc
     2221 actattttat gctacaataa ccaaaacgtt cgagcataaa aaaggaggga aagacgtgta
     2281 tttgtcttcc gagtatctta aacaatttga taaagatcta tattataaga ttctcctcct
     2341 agaaagtttt gaggatcaag cttggcatac cgctgcacaa ttagcgcaag ttgttcagct
     2401 ggatgcccgc agcgtgtcga aatacctgaa cgagctgtct aaaaactatc agcagtttag
     2461 cggtaagaca caccctttgt ttacaaaaaa tcaccgttct ggttataact tttatgatac
     2521 gctcgattca attgaacatg agcgtttttt gatctatctc gtgcaaagta cgctgaaatt
     2581 ccagttgctg cacgacattt tttttgaaga attccataca atgtaccaat ttgcgcaaaa
     2641 gcattacatt agtgaatcta ctgctcatcg aaaaatcaat gaatggaaac agcaactgca
     2701 aacttacgga attcggctgc aacgaggtac atatatcgct caaggcgaag aagaaatcat
     2761 tcgactttac ttgcatatga cattctggca gttgtttcga gggaaaatct ggccatttga
     2821 aacgatttct caaatggacg taaagaatat ggcagaacat atcatggctt tttttaatgt
     2881 tcgtctgaac gagatcaaaa aaagacgatt ggaatatatg ctaggtgcct tttttttaag
     2941 aaaatcacag aagcattatg ttgtattgaa tgagaaaaaa agacggctga tttctgacaa
     3001 tctgttgttc cagcgatttt gccaggtcat ggagccggta tttcctaatt attttcaagt
     3061 agaagacgag ttaggcgcat tatttcttgt actgatgact cgtgaagaat attatagtga
     3121 tcctaagata cggaagaaaa tttttgattt tcatcaacaa gcaaaaacac cgccctttac
     3181 agccctttca gaagcaaaag ccgctctttc tctttatcag gaagagcagg ggctgccagc
     3241 agaaaatcta accttcgagg cagaaaacta tttattcagc agtcattttt tcgcctatct
     3301 ttttcctaat gcgaaagaaa cgattgatgg caatagtagt gattttatta atcatttagt
     3361 tattgaaaac aaggaattga aacaatggct cgtacatttt tttgaaagta gacacaaaca
     3421 tcccaatcat ctggcattta aaaatcatgc gtttttgatg gggcggtatc tgactgtgtt
     3481 taaaacatta ggagccttta ctccacagct tccaaagatc acgatccttt taatgacaga
     3541 tttcccatta tttgaagagc aactgttaga ggagggatta cggacatttt tccgtaatga
     3601 gtatcagctg atttttctgc caacagatta tcgggggaga gaagttgatc ttctgatttc
     3661 gacaagtaaa gtccaccgca aaccatgggc ggatcttgac tattttattg tgactgaaga
     3721 actaaaatta attgattaca tccaactatc tcaaaaattt gaaatgattc aaaaacaaaa
     3781 actattaaaa caataacaaa gaaggagaaa aaagatgaca tttgaagaaa ttttaccaga
     3841 attgaaaaaa ggtgcaaaga ttattcgtaa aggatggagt ggatttgaac tttatgttgt
     3901 tctcgtatcc gatgatgaat ttgatggctg tccggtgacg ccgtacttat tgatcaaaac
     3961 aagtgacgaa ggtttttcca gcttcgctcc tacagtttgt gatattttag cagatgattg
     4021 ggcgatcgta gaatgaaaaa ccagtatcca gatctagcta aacaggttgt atttatcaca
     4081 ggagctgctt ctggaattgg tgctgcgcaa gcccgagcgt ttcttgaaca agatgctttt
     4141 gtatttggat tagatcaaaa gttcggtaaa atggaagaaa tttctttgcg atttcctgaa
     4201 acttttgcct acgcactagg tgatgttcga caaatgaaag aactccaaca agcggtatcg
     4261 aaatgccaaa atcattttgg tgaagttacg attttactga atacagcggg gatattggat
     4321 gcctacaaac ccttgatgga aactgacgaa tcgctgtggg atctgattta tgagacgaat
     4381 gtgaaaagca tgtatcagct gacaaaaatc atccttcctg atatgatccg ccaaaaaagc
     4441 ggaacgatca tcaatatggc ttcgattgct ggcttgattg ctggtggagg tgggatcgct
     4501 tatacaagcg cgaaacatgc gattgtcgga tttaccaaac aactcgctct ggattacgca
     4561 ggacagggta tccgagtaaa aggaattgct ccaggagcca tccaaacacc aatgaatgcg
     4621 gctgattttg aagggaaagg tgagatggca gagtgggtgg caaatgaaac accagtcaag
     4681 cgatgggcac agccggaaga agtagctgag ctgacgttat ttcttgcctc tcctcaagca
     4741 agctacatac aaggaacgat catcccaatc gacggcggat ggttgttaaa ataaccttgt
     4801 gtttttttca agcttctgta tgataaaact aaagagagaa acaacggttg atgataaaaa
     4861 aagtcgatga ctgttcccga cattcgatgc cgaacagcca gttcaaaaaa ttctttttaa
     4921 taatcgttaa tattcgaaac taagcggctt ttcacgacct cttgatataa acgatattca
     4981 aaagcttgca actgcggtaa caagtccagc caaatgaaaa atataaggag ctatttttat
     5041 ttgaccattc ttattacttg ttgcagggca gctttttcac taccttctgc gacacttcag
     5101 ttggaatttt cttcccatcc tttggtcgcg gtcattacca agataaaatt atcttgcaaa
     5161 ggagaaatag aacatggaaa aaaataatac ccgttcagcc aaacgctgga caacgacaga
     5221 tgtgactcgg atggcgctag tcactggttt atatgtggca gtgacgctgg ttttgtctgt
     5281 ctttagcttt ggagtgattc agattcgtct ctcggagatg ttcaactatc tgtccttgta
     5341 taacaaaaga tacatcgtcg cggtaacagc gggagtagct ttggctaata ttgcttctcc
     5401 tcttggactg atagatgttg cagtaggaag cgtcagcacg ctgcttgtat tgcttatcaa
     5461 ctataaaatc actagtcgca tcaaaaacat gaaaatcaaa atggccgtga cagcatgcgt
     5521 atttgctttt tccatgttta cagtagctgg tcagctaacg attttatatc aactaccttt
     5581 tttcttgaat tggtgggtga ttgctttagg agaattggca tcaatgattg tcggtgggat
     5641 aattatttat tggatcggta aaaaagtgga tttgtcaaaa taaagatctg tttaatttaa
     5701 aatagggcag catggaagag actgaatgtt gagtcttctt ccatgctgct tttttgatta
     5761 atttgtatga agaaatcgat ttagccgttt tttcatcaag ataccgatat aagctgctcc
     5821 agttgccttg attgcttccg gcagtaaaaa cggcagtagt ccactggcaa atgcagttgt
     5881 aaaagtaaga tcaccactta ttttcagcca gatcgttccg cagatcaatg cagcaagaga
     5941 gcccattaga ttggcaaaga ttgcatataa gtaatgagca tccgttcttt cgatcatcca
     6001 accagttatc cacgtttgta agagaaatcc aatcaaatat ccgccagttg gcccaaataa
     6061 aacagctata cctccagtca tccctgaaaa tacaggaaga ccaatcaagc caagtaaaag
     6121 ataaactcca acagatatca atcctagttt tcttccgaga aaagttgctg ttaatccaat
     6181 agcaaatgtt tgccctgtca aaggaaccaa accaaaagga atggtcatct gagaaaggac
     6241 agaaataatc gcggcaaatt ccgcagcaag tatcaattct ttcaatgttc ggttcataac
     6301 gccctctttt cgttaactta atatttttat ttggttaacg aaattgtaaa acaaagtgat
     6361 tactttgtaa atagaaaata taaaaa
//
LOCUS       DAPBAF010000087         6313 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.091, whole genome shotgun sequence.
ACCESSION   DAPBAF010000087 DAPBAF010000000
VERSION     DAPBAF010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6313)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6313
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.091"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            330..1175
                     /locus_tag="RD451_002734"
     CDS             330..1175
                     /locus_tag="RD451_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDT7567919.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
     gene            1456..2676
                     /locus_tag="RD451_002735"
     CDS             1456..2676
                     /locus_tag="RD451_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair exonuclease"
                     /protein_id="HDT7567920.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSYQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            2673..5393
                     /locus_tag="RD451_002736"
     CDS             2673..5393
                     /locus_tag="RD451_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDT7567921.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            5377..>6313
                     /locus_tag="RD451_002737"
     CDS             5377..>6313
                     /locus_tag="RD451_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HDT7567922.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPK"
BASE COUNT         2354 a          976 c         1223 g         1760 t
ORIGIN      
        1 aaggcaaaaa gatgaactag aaatagttca tctttttttg tttaaatctt ttgctaagtt
       61 gaactaatag agtcttttat gaatatcgaa gttagttttt cacctaactt cgttttttat
      121 agttggttat tataaaatag taatatagct gatttggatt caattcatat ttatttataa
      181 atcaaaaata cagagaatag tatataaatg tcctttccta ttcttaaaat gatgtttgta
      241 cttacttaaa ttaggtataa ttagtatatg ttttgtgaga aatttagact tacaataagc
      301 agtgaattta taatcaacgt ataggagaca tggatgaaat gaaactaatt ggtatagatt
      361 tagacggtac tcttttgaat tctgaccaga gcattagtca aaaaaatgca agaacaatga
      421 aacatttacc ggaagactgt tttccattca tttgttctgg aagagaagta gaagacatta
      481 ataatattct caaaaaatct ggtttaagga taccagcagt agggttaaat ggttctgttg
      541 gatttgatgg agaaaaaaag atatttgagt cttccttcga taaaaatgat gtaaaaaaaa
      601 ttgattctgt cctatcgaaa tttccaacca aaatatatac aaatctcgga agttatgaat
      661 ctcagaatta taaaaataaa atgaaaaaaa tttttcacga ggtagggagt gaattttcta
      721 tcaaagagct aaactatgag cttgagtatg aaaaatctat ttgttcaatc ccttataata
      781 atattgagga aattatagaa aaggatgcta tcagcattta caaatttttt atttttattc
      841 ctaatcgtca attgaaagct aatatattta accatttgaa aaagatgcta aatgtgtctg
      901 ttactgaatc ggcacctgta aatattgaaa tcgtacctca aaatgtatct aaaggtgtgg
      961 tgtttgatcg tttggaatca atctacaatt taaagaaacc tttgagaatc gcgatcggag
     1021 atagtttaaa tgacttatct atgtttgaaa gtgcagatat tagttttgca atgggaaata
     1081 gtcatcaaga aatcatgaaa aaagctgatt atgtcactgt ttcaaatgat aaagacggag
     1141 tatctcaagc atttgaaaga attcttacca tataaactaa ttaaggtagt atagaacata
     1201 gaattctaaa tacggaaaaa tggagcataa attccagtac aaatagtact tcttcagtgt
     1261 caaacgaagc gaatataaca tagatattta ggattgtgac aaaaatcatg tcacaatctt
     1321 tttttcgaat aaacttattt tttgaagtcg gccatttatc gtaatttctt tgcataatac
     1381 gaacaaattt tcggttattg atgaaaaaaa acattgaaaa tggtatgata aaagaaaaaa
     1441 aggaggaaat ttttaatggt gaaatttatc catgcggcag atttacatat ggatcggtca
     1501 tttgaaggac tgacaactct tgataaaact gtacaggaaa aactattgaa gacgaatctg
     1561 accgttttat caaatatcat tgaacaggca ataataaata acgttgattt tgttttactt
     1621 gcaggagata attttcatca aaatcgtcct tcattaaaaa tacagaaaca tttttcagaa
     1681 cagatgaaac ggttagaaaa gaaccatata cctgtattta taatattcgg aaatcatgat
     1741 ttctatcaaa aagagcggta ttggttctcc tttcctaaaa atgtccattt atttacatcc
     1801 gaaacggtag agacaaaaaa aataacgata aaaagtggag aaactgtctc tctcagtgga
     1861 tttagttatc gtcaaccgtg gattcaaaaa gacaaagtga tggaatttcc ttctagagaa
     1921 ctcacagatt accatattgg gttgtaccac ggggaacctg gcgtctctca aaaaggaaac
     1981 tatgctcctt tccaaccctc aaagatgcaa gaaaagggat acgattattg ggctttaggg
     2041 catatccatg tgccaacggt cttaaatgaa aagcaaacaa ttgtttatcc aggtgcgcct
     2101 caaggtcata ctaaaaagga acaagcttct acatctattc tactagttga attaagtaaa
     2161 ggaagttacc aaatacatcc gattaaagta gcagaggtct attggaagac aaaggaaata
     2221 tcattgagga aagcaagaac gacaaaagag gtcattgttc acattcgtca gcagctttca
     2281 aaagtagagg atggatttag tttaattgag ataaaattaa aagattatga ccatctcaat
     2341 acagatgttt tggaacggat acaatcagga gagctattag actatttgtt agaggaattc
     2401 tcagatagga taaatgattt ctttatttgg cgtatttctc tcatagagaa tactttttat
     2461 acgaagaccc cacttgctgc ttctgctaaa ttgatggaac agttatttca atactatcag
     2521 acacctcaag atttccaaca aattttaaat gaagtatata gtcatcaaga agcggctaga
     2581 atattgagcg aactgccgga atatcaagaa gaaacacttg aaaaagccaa gcagctgctt
     2641 aatcaagatt ttttatttga ggaggatcag gaatgaagat tttaaggatc gagattgctg
     2701 cttttggaaa atggcgtcaa aaaagttttg acttttattc aggcaatcag ctgatctatg
     2761 ggggaaacga agcaggaaaa tcaacgattt atcaatttat tcaagcaata ttatttggtt
     2821 tcccttcaaa aggccgtaaa aaaaaggatt atacaccaaa agacggctca gcctatggcg
     2881 gcaaaatatg gcttaaacat cctgtatatg gtgaatttgc tgtcgagcgc tacaagcagc
     2941 aaaatcgcgg aaaatcgaag gtgtggctgg gggatcaagt gggaagtgat gagttactag
     3001 aaaaactgat cgcacctttg acgaaagagt tattccagca ggtatttact ttccagcaag
     3061 agcagttgat ggaactagat catttgagag aaaaagagct acatgatgcg ctgatttctt
     3121 taggcatcac gggcagttct caagtattcc aaaagcggca agaatattat cagaaagcac
     3181 aacaattatt caagaaaaaa ggccaaaaat tactaatcaa tcaaaaatta aatgaatgga
     3241 aagagctgca agaaaaaatt catcaaaaac aagaacagga agcttatttt ggcaagttga
     3301 tccaacaaga acaggaatac gagtcgcaac agcagcagtt attggcacaa ttaaaagagg
     3361 cgaacaaaca attttcatta gccagacagc aagaacttaa tttttcttta tatgaagaat
     3421 ggcaatctct caaaaaaaac agcactacag gtcttcctga tgagcaactt cttttagatc
     3481 tggagtcttt ctccaaacgg tatcagcaaa caaatgagcg tttggaagaa ttagaagcaa
     3541 cactggaaaa gcatagcggg atggatcagc agtcagccag atattatttt tatttagagc
     3601 aggagcagga actaaaagat ctccagcaac ttcaatttac agcggaacaa ttaaacgaag
     3661 aatggcaaag attacaaatt gagactagag aaacaaattc agaattgaag attttggaac
     3721 aaaggtggca ttggcagaaa aatccgttac cggaagaatt tttatatgaa gaagaatgga
     3781 agcatcttct ggctgaagaa agaaggattg ctgatctaga aagccagatt tctgtgcgtc
     3841 tccaaatagc taaagaacag caagagatga ttgaagcaga agtgaatgac ttggaagaga
     3901 cctatccagc attattacaa aatcagtcag agatagcacc agtctcttca tctaaaccgt
     3961 atatgctgat ggctggcgga gcaataatca ttgcaggtat atttgtacca atgcccttga
     4021 aagtgatcct tttactaatt ggtgcaggca tgattggcta tttcttctac aaaaggcaac
     4081 caaaaattaa aactaaaaat gatttctctg agataaaagg aatgtggcaa gaaaaactag
     4141 gacaacttga tctagcctta gctcaattag ctgaagcaga agaaaaacaa aagagaactg
     4201 gagaagaaaa acagattctt cagcaagaag tatatcgttt tgcggatcat cggcacttag
     4261 gaaagatgga tacgctcaaa ctcatgaaag aatatggaca ggaagtcata gattatcaga
     4321 aattatatgg cgtatttgag cggaaacata aaagagaaca ggaaatacaa gaaaaactac
     4381 gacaaatcga ccaaaaattt gagtttgtta aagaatggtt accgatacaa gataagacaa
     4441 tttcagaaaa aatggtattg ctttcccgtt ttatacaaga gatggaacag atgaaatttg
     4501 ccagaagcta tcagcaaaat actttattga agcaagaaat caatcaattg aaaaagaaac
     4561 aaaaagtatg gatacaagaa tacagcgaac aattgactca agcaggctta tcttatcctt
     4621 cggaagtacc tgtcttttta caaaaagcca aacaagccga acagcagatg aaaagataca
     4681 atgaattatc ggaaatgctt actccactat ttcctgaaga gctgacaaaa gagaaattat
     4741 ctgtaagact gcgccaactg aaagaaaagc aatcccaact ccagcaagaa gaaaaagaag
     4801 caagtgaaaa tcggcaacga ctccaacttc aagtagaaga gttgcaaaga gacggcacat
     4861 tggacgaact ttatcaacaa gctagccggc aaaaagcaaa attacaggaa ttactggagg
     4921 aatggggagc acttgaaatc gccgggacat tcttaggtga tctttcaaca gagatgagtg
     4981 aaagacaatt accccagttg ttaagagcag caggtgatta tttaggtatt ttaacaaaag
     5041 gaaattatca gaagatatta ctgaaaaatg atacactgac tttaacagac ggatatacag
     5101 aatttcccat ctatgagtta tctacaggta cgaaagatca gctgattatg gcgatgagat
     5161 ttgcttacct ctcattagaa gctaaccgtt cgatatgccc gatcatcatt gatgatggct
     5221 ggcttcatta tgatcatcag cgaaagtatc aattagctga acttttagct aaatttggag
     5281 aaaagtatca aataatttgt ttttcttctg ataaagaaat ggtaagctat taccatgaga
     5341 tgaaccaaat cgtaaaacaa ttagaaggag caaataatga aaaaaattcg tgatttagta
     5401 atcgatgagc agtttgaaca atttgtcctg atcaaaagtg cagatgtaag aatcgctaaa
     5461 aacggaaaaa aatttattgc ttttactttc caagatactt caggtactat cgatggtaaa
     5521 tactgggatg cttcggagga ggaaatcaat aaatttacag ccggcacagt cgtttttcta
     5581 aacggtaaaa gagaggttta tcaaggaaac cctcaagtaa agattcttca tatgcgctta
     5641 acaagggtag atgagccagg agagcctagt ttatacatgg aaagagcccc tttgaagaaa
     5701 gaagaaatgg aagaagaaat caatcaattg ttgtttgaga tcaccaatgc gcattggaat
     5761 cgtattgttc gctatctact taataaatat caaaaacaat tttttgagtt tccggcagca
     5821 aaaagaaacc atcatgcatt tgccagtgga ttagcttatc atactttgac aatgcttcac
     5881 ttagggaaat caatcgccga tgaatatcct gagctgaatc gagcattgtt gtatgctggt
     5941 atcattttgc atgatttagg aaaggtgatt gaactttccg gtcctatgtc gacagaatat
     6001 acgcttgcag gaaatttgat cggtcatctg gtattgattg acgaagaaat aactaaagcc
     6061 tgtcttgcgt tgaaaatcag cgaagctgac gaagatgttc ttgtattacg tcatatggtt
     6121 ttagcacacc atggcttatt agaatatggc tcacctgtac gtccaagaat aatggaagca
     6181 gaaatattac atcaaatcga caatatcgat gcttcgatgc agatgatgtt gacttcgatt
     6241 cgtcaaacag aaccaggaaa atacaccgat cggattttcg gtatggacaa ccgaagtttc
     6301 tatgtaccaa aag
//
LOCUS       DAPBAF010000088         6173 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.092, whole genome shotgun sequence.
ACCESSION   DAPBAF010000088 DAPBAF010000000
VERSION     DAPBAF010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6173
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.092"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            725..811
                     /locus_tag="RD451_002738"
     CDS             725..811
                     /locus_tag="RD451_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HDT7567923.1"
                     /translation="MFELFICPLLIEVCVSLFSYWLNNRNKK"
     gene            complement(932..1621)
                     /locus_tag="RD451_002739"
     CDS             complement(932..1621)
                     /locus_tag="RD451_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567924.1"
                     /translation="MAFYLPYLLIFASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLP
                     GVIFTLSIVLSGLFGVLEGNKRISRSILLGDITQKYEAACDKKKKEQVLTQKMEEFTT
                     CYEEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYFKDTQT
                     EEACYNLFSDTIPFSTSEQERKERQQSVTYERYKALLQQATNIQNPTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(1866..2780)
                     /locus_tag="RD451_002740"
     CDS             complement(1866..2780)
                     /locus_tag="RD451_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HDT7567925.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGNKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRFAIDQTMKNKKTRTYNQFCDSLKTFGIHCLNRGKNFTYELIHKKK
                     KVRSNKLGKDYEKETILHELDRRERAYNQQRTNELRRARASIRETAKEVRREQRTLTT
                     EQPEIRPTRRNHDQHVERGADYQQELSF"
     gene            complement(2762..3142)
                     /locus_tag="RD451_002741"
     CDS             complement(2762..3142)
                     /locus_tag="RD451_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HDT7567926.1"
                     /translation="MSEQNQYLASNHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVDPG
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            complement(3592..3879)
                     /locus_tag="RD451_002742"
     CDS             complement(3592..3879)
                     /locus_tag="RD451_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HDT7567927.1"
                     /translation="MDFTKEEKLLNAISKVYNEATIDDYPDLKEKLFLYSKEISEGKS
                     VGEVSMKLSSFLGRYILKHKFGLPKSLIELQEIVSKESQVYRGWASIGIWS"
     gene            complement(3899..4123)
                     /locus_tag="RD451_002743"
     CDS             complement(3899..4123)
                     /locus_tag="RD451_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin hiracin-JM79"
                     /protein_id="HDT7567928.1"
                     /translation="MKKKVLKHCVILGILGTCLAGIGTGIKVDAATYYGNGLYCNKEK
                     CWVDWNQAKGEIGKIIVNGWVNHGPWAPRR"
     gene            complement(4578..4748)
                     /locus_tag="RD451_002744"
     CDS             complement(4578..4748)
                     /locus_tag="RD451_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567929.1"
                     /translation="MTKKHLLFGSILLGILSFSPMLLSVANKGNKKGELKLNPNYYNS
                     QNEEVFVEKLDK"
     gene            complement(4763..5296)
                     /locus_tag="RD451_002745"
     CDS             complement(4763..5296)
                     /locus_tag="RD451_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HDT7567930.1"
                     /translation="MQPQETFTIKELSDLFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLDNQRLLDKLHKHEQNNDKNAYIPNKNVVANKLLDQLREENEFLRE
                     QLALKEQNNSHIQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENSSTTLSEATE
                     TMDEQTKNWKKWWQLWK"
     gene            complement(5317..6159)
                     /locus_tag="RD451_002746"
     CDS             complement(5317..6159)
                     /locus_tag="RD451_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HDT7567931.1"
                     /translation="MREKGDKTVRFTFDQLKDLSNYKATANVRFVEDLKATYEKILSL
                     RFGRRSESGLSYDMFVMFTEFKINGDVENPYVDIRIYEKALPLLNNLDEWVRYSLQQF
                     NELQSGYAKTMFRLLKQYRTKGFAYFSKEDFLELLDIPKSYKQPDIDKRVIKPIRQEL
                     TAIFKGLTIKKKYGKGRGKPVIGYQFTFKPEIKKADDFNKHAPTKEDQNKALALADKQ
                     KEYEEPATTINEKIKQKKRELELLQQIKQLEKEKKALEKQTESALSEKEKKSLLSDLD
                     NLFQ"
BASE COUNT         1633 a         1151 c         1042 g         2347 t
ORIGIN      
        1 aaaaaaacaa attcatttca accggtgtaa attttcttaa aggaattgta tttaattcat
       61 ggtggtattt tacaatctca ttagccatat aatcacctca atccaattat gaatgacatt
      121 ttttaaatgt caagacattc atatttgacg ttcaaacaga caaaatgtcc ttcataaaca
      181 gacaaaatgt ccttcataaa cagacaaaat gtccttcata aacagacaaa atgtccttca
      241 taacattctg tatccattgg tagagtaagg acacagctta cggtaaagag gtttaaaaag
      301 aggtttaaaa agagatataa aaagaggggg gctaattttc ccgcctaaaa accacttctt
      361 ttttctttaa acaggttcgc gcatttttca aaactgccaa tccaaaacct tgcttcctac
      421 ggtcgccaaa aaggtgtgat cgctacgctc tcacattgta ctgcgcagtc gcctaaaggc
      481 tcctttgcta aaaacatgtt ggtaaagagg cctttgagcg gttctgaatg cttatctaag
      541 ccgttttaag acagtcttgg ataaaaatcc ttatctagct ttaaagcgcc ttacaggcgg
      601 tcagggcaag ccctaacaac cctaaaataa gcgatactta aaaacaccac acaagtttaa
      661 ttttttaaga tataataact tgtcgcctat ccgacagtct tgcgactgga aggaggtgta
      721 tctaatgttt gaattgttca tttgccccct tcttatagaa gtttgtgtct ctttattcag
      781 ttattggttg aataaccgaa acaagaagta aaatcaataa aggcgacatc aacctgaaaa
      841 aaagccccag agaatccgac ctctctgggg ctttcgtgta tctaatgttt gatcatttgc
      901 atgtttagtt taacatgatt gccgatcaaa ttcaattttg ctgttgctga tctaaccatt
      961 ccttgacact ttttagataa tttaatgccg tttctttttt cgttggattt tgtatgttcg
     1021 ttgcttgctg aagcagtgct ttataacgtt cgtaggtaac tgattgttgc cgttcttttc
     1081 gttcctgttc actagttgaa aaagggattg tatcactgaa taaattataa caagcttctt
     1141 ctgtctgcgt atctttaaaa tattgcacgt cttttttggt tcgctcatag ttgtcttgaa
     1201 cctctttttg ctgtttttct ggcaagtttt gataaagacg agtgagtttt tccatgtttt
     1261 tatccgtcaa acgtttttct tgattcacaa aaatatcgtt catttcctca taacaagtgg
     1321 taaactcttc cattttttgt gttaacactt gctccttttt ctttttatca catgctgctt
     1381 catacttttg agtgatatcc cctaataaaa tacttcttga aatacgttta tttccctcta
     1441 aaacgccgaa taaaccactt aaaacgattg ataatgtaaa tataacccct ggcaataaaa
     1501 acctcttaaa tcgaatttta gagcctttta atgaatatct tgtttgataa gccttatagc
     1561 taagccaaat aattcctaaa atactggcaa aaatgagtag atagggtaaa tagaatgcca
     1621 tttctattta ttctccccat accagccaaa aggctaacag tgtcatgatt aagcaacata
     1681 agggggcaag aatatccatt gatcgctgca taattacttt tttctgttct ttatttcgct
     1741 ggtttaatag cgcatggtgg aattttttga cttgtgaatc aattgtagtt tgtattcttt
     1801 ctttggtata aggtgcaaga aaagcacgtt gtttctttat ttcattttct atgtcttgta
     1861 acgttttaga acgataattc ttgttggtag tctgctcctc tttcaacgtg ttggtcatgg
     1921 tttcttcgag tcggtctaat ttccggttgt tcagtcgtaa gagttcgttg ttctcttcgt
     1981 acttcttttg cagtttcgcg aatgctagct cgagctcttc gtagctcgtt ggttcgttgt
     2041 tgattgtagg ctcgttctcg tctgtccagc tcatgtaaaa tcgtctcctt ttcgtaatcc
     2101 tttcctagtt tgttggatcg tacttttttc tttttgtgga tcaattcgta agtaaaattt
     2161 ttcccacgat tcaagcaatg aatgccgaat gttttaagag aatcacaaaa ttggttatac
     2221 gttcgagttt ttttgttttt cattgtttga tcaatcgcaa accgaatttc gtctttccaa
     2281 acaggttcat ttttttcttt taatttgatt tcagacatgg ttcgtttttc gggtttcttc
     2341 cctcgttcag tgattgttaa gtcatgttca agacaaatct cgtcatttag gtcataacat
     2401 ttgtttaaaa atgcttgacc atgggcttga aatttgttcc cagtttccag attgacggag
     2461 ttaatgacaa tgtggttatg aatatggtct ttgtctgtat gtgtgtaaat cgcgatttgg
     2521 tggtcagggg ctattttttt cgcatactct gcccctagtt gattggcttt ttcagcggta
     2581 atttctcctg gtcgaaaaga ctggatcaat aagtgtgctt gtacacgatc gtcttttcca
     2641 tacagcatgc gaatttgttt catttcgctt ttggcataat caatgtcaca gtttatccct
     2701 gttttgacgg ttgctcgtgg ttcggcgtaa ttgatcgctc ggctacaaga agtggttcgg
     2761 cttactttaa ctgttgccat atcttttgta gctccttttg catgattttt aggttttcgg
     2821 ataagcgttg ggcgtcgcca ggatcaacgt cgtgttggtg tgtgttgcac cacttggcaa
     2881 tttgattgat attcccgcca gctttggcta aatcgcgcgc gattgcctga gcaatgtctg
     2941 gcgccacttt cggtgtcacc agacgcgcgt tttgtgcctt ggctttcacg aaagccggca
     3001 cactcatttg caaagcttca gctgactgct tcagctttgc aaattcggat tcgctcactc
     3061 gaaaactgat ttgttttggc tcggatcgat aggtatattt tttagaatga ttgctagcca
     3121 aatattgatt ttgttcgctc ataagtccca ccctttcagt acgtcctacg gacgtatcgt
     3181 tcgcaatacc attgtaccta aaaaggtaca ataagtaaag ctcactaaag ctcactaaag
     3241 ggcttggcaa gctctatatt tgctagccaa atacctacgt atttggtgca aataaccgct
     3301 tgtcaaaggg gcgcaagctc ccccttgaat ccccctcccc cccactctcc acaatacaaa
     3361 aaagactagc aaatgctagc cactttttgt aaagtttcgc ttgtttcacc ttcggtgaaa
     3421 ttgttgcaaa tcaataatta ggtagagcta catttttttc gttgttcaaa gattcttatg
     3481 ccatttacta ttaataaatc tataaatatg ataatttttc ggctctataa tttatgggac
     3541 tgatgaatca gaattgattc ttcagtccca ttttcatttt attccaaaga attaactcca
     3601 aataccaata gaagcccatc ctctatatac ttgagattcc ttactaacaa tttcttgtaa
     3661 ttctattaaa gatttaggta atccaaattt atgttttaaa atatatcttc caagaaaact
     3721 acttaatttc atactaactt caccaacact ttttccctca ctgatttctt tagaataaag
     3781 aaagagcttt tcttttaagt caggatagtc atctatagtt gcttcattgt atactttact
     3841 aattgcattt aaaagttttt cttctttagt aaaatccatt ataataacct ccctaccact
     3901 accttctagg tgcccatgga ccatgattaa cccaaccatt aacaataatt tttccaattt
     3961 ctcctttagc ttgattccaa tctacccaac atttttcttt gttacaataa agaccatttc
     4021 catagtaagt agctgcatca acttttattc ctgtaccgat gccagctaga caagttccta
     4081 atattcctag aataacacaa tgttttaata ctttcttttt catgattgtt tttccttttc
     4141 gtttttttaa aattgcttgt tatattaaat aatcttagta attttattat ataacatttt
     4201 attatataac aatgattaac gtcataaaaa gtagttttga attcataatc gtttaaataa
     4261 aattataaga tcagttattt aaacagctag tagacataat gtgtatacta ccaagtaacg
     4321 cctgtaccaa gggatccagg cgctgatttt gtgaattttt attggtctag gttaaaagct
     4381 ctttttaagg cttggttttc tgcggttgtt tctttctaat tctttgtgaa tattgatcgg
     4441 tcatttttta aatacttgtt atttttgttt gtgtttgtta tgctttttac atatctcata
     4501 ttcatttatt attcttttct aaggttaata ataggataat ctctttcaga aagactgctc
     4561 gtacgagcag tcttttctta tttatcaagt ttttctacaa atacttcctc attttgactg
     4621 ttgtagtaat taggattgag ttttagttcc ccttttttat ttcctttgtt ggccactgat
     4681 aataacattg ggctaaagct taatattcct agtaggatag aaccgaatag caagtgtttt
     4741 tttgtcataa gtatttcctt cttcatttcc atagctgcca ccattttttc caattctttg
     4801 tttgttcgtc cattgtttct gttgcttcag aaagagtcgt tgaactattc tctgaagact
     4861 cttccgtata agtcaactgc agttgctcct gaagtttttc gatttgttgg ttggcttgca
     4921 gggtgagttg ttgttgctgg tcgagtagtt tttgtatatg agaattattt tgctctttga
     4981 gggcaagttg ttctcgtaaa aattcatttt cttcacgcaa ctgatctagc aacttgtttg
     5041 caaccacgtt tttgtttggt atataagcat ttttatcgtt gttttgttca tgtttatgca
     5101 acttatctag caacctttga ttgtctaagt tgcgagcaag ttgcaatact ccagaacgca
     5161 atacaacctt ataaccacgc tcatttttag ctatcatgga agaatctaat ttttggatat
     5221 gtttcgatat tgcttgccta ctcatcttaa aaagatctga caattccttt attgtaaagg
     5281 tttcttgtgg ttgcatactg gttgcctcct aggttgctac tggaataaat tatctaaatc
     5341 agataataaa ctttttttct ctttttccga aagtgcggac tctgtttgtt tttcaagagc
     5401 ttttttctct ttttctagtt gtttgatttg ttggaggagt tcaagttctc gtttcttctg
     5461 tttgattttt tcgttaattg ttgtagcggg ttcttcgtat tctttttgtt tatcagctaa
     5521 agccaatgct ttattttggt cttctttggt tggtgcatgt ttgttaaagt cgtctgcttt
     5581 tttgatctca ggtttgaacg taaattgata gccaataaca ggttttcccc gtccttttcc
     5641 gtatttcttt ttgattgtta gtcctttgaa gattgcagtt agttcttgac gtataggttt
     5701 tataactcgt ttatctatat caggttgctt ataactttta ggaatatcta ataattcaag
     5761 aaagtcttct ttggagaaat atgcgaaacc tttggttctg tattgcttta acagacgaaa
     5821 catagtcttt gcatagccac tttgtagctc gttgaattgt tgtaaagaat agcgtaccca
     5881 ctcgtctaaa ttatttaaca aaggcagtgc tttttcgtaa attcgtatat ctacgtaagg
     5941 attttctacg tccccgttga ttttaaattc tgtaaacatt acaaacatat cgtaagaaag
     6001 cccagactca cttctacgac caaagcgtaa agataagatt ttttcataag ttgcttttaa
     6061 atcttctaca aatcgtacat ttgcagttgc tttgtagtta cttaaatctt ttagttggtc
     6121 aaacgtaaaa cgaactgtct tatccccttt ttcacgcatt ctagacacga tgg
//
LOCUS       DAPBAF010000089         6135 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.093, whole genome shotgun sequence.
ACCESSION   DAPBAF010000089 DAPBAF010000000
VERSION     DAPBAF010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6135)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6135)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6135
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.093"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(207..1169)
                     /locus_tag="RD451_002747"
     CDS             complement(207..1169)
                     /locus_tag="RD451_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004233175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDT7567932.1"
                     /translation="MVAKLTDVAELAGVSPTTVSRVINNKGYLSEKTKQKVHEAMKTL
                     GYKPNNLARGLQGKSPQLIGLIFPNISNIFYSELIEYLEIELFKHGYKTIICNSQNDP
                     AKEREYIEMLEANQVDGIISSSHNLGIADYERVRAPIVAFDRNLAPNVSIVSSDNFEG
                     GKLAAKTLQKNGCQNTIMITGNDNTDSPTELRALGFSFQNPNGKIFKIPNNLSTIRRE
                     MEIKSTIINHKPDGIFVSDDLTAILTMKIAHQLKLNIPEDLKIIGYDGTSFIEKFFPQ
                     LTTIRQPIDEIASLIVDILLKKIKGEKTNKDYILPISILSGGSI"
     gene            complement(1171..2610)
                     /locus_tag="RD451_002748"
     CDS             complement(1171..2610)
                     /locus_tag="RD451_002748"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HDT7567933.1"
                     /translation="MNLPREIRYRAYSDWTKDEMDKIKDNVKRSPWRASYHIEPKTGL
                     LNDPNGFSFFNGKYTLFYQNWPFGAAHGLKEWVHNESDDLVHFHVTGAELLPDTKRDS
                     HGAYSGSAYEIEGNLFLLYTGNVRNENWERDTLQIGAWMDKDYNITKGENVLIHKPAD
                     VTDHFRDPQMFNYEGQLYAIVGAQNLEKSGFIKLYKADDNNVETWEEVGNLDFGGTGS
                     EYMIECPNLVFVDKKPVLIYCPQGLDKSELNYGNIYPNTFKICQSLDIEKVKLVGASE
                     IQNLDYGFEAYATQGFNTPDGRALIVSWIGLPDIDYPTDKYDYQGAMSLVKELSIKDG
                     KLYQYPVEAITSLRASSEQFTAKAETNNTYELELTFPPNQKSELLLFSDSKGNGLSLI
                     VDTKEGKIILDRSKAGIQYATDFGTIRECSIDTKETTANIFVDNSIIEIFINKGEKVF
                     TSRVFPENHQNGIQIKSGEPTGKYFELKY"
     gene            2795..4741
                     /locus_tag="RD451_002749"
     CDS             2795..4741
                     /locus_tag="RD451_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HDT7567934.1"
                     /translation="MNYSKVASDVIQAVGKDNLIAAAHCATRLRLVLKDDTKVNQKAL
                     DENPDVKGTFKIDGQYQVIIGAGDVNFVYDELIKKTGLSEISTDDLKQIASKDKKFNP
                     IMALIKLLSDIFVPIIPALVAGGLLMALQNFLTAAGLFGPKSIEEMYPAIEGISSMIQ
                     LMSAAPFMFLPILVGISAAKRFGANQFLGAAIGMIMTTPDLGGSTEYWNIFGYHVSQT
                     NYAYQVIPVLAAVWILSILEKFFHKKLPSSIDFTFTPLLSVMITGFLTFTVIGPVMLL
                     LSNGITDIIVWLYNTTGFIGMGIFGGTYSLIVMTGLHQSFPAIETQLLSAWTNGIGHG
                     DFIFVVASMANVAQGAATFAIWFLTKNSKTKSLASSAGVSALLGITEPALFGVNLKYR
                     FPFFCALIGSGIATAVAGLLKVVAVSLGSAGFLGFLSINATSIPFYVLCELISFVVAF
                     AITYFYGKTKAAGIFKAEEIAEQTPVNSSKVATTDPISTDVESTQTKVSSETIVSPIS
                     GKVISLSSVNDPVFSSEAMGKGIAIKPNGNTVHSPVDGTIQLTFETGHAYGIKSNNGA
                     EVLIHIGIDTVSMGGKGFTQKVTTNQKVRKGDILGAFDRSMIEKEGLDDTTMIIVTNT
                     SDYSEVNIVAENTVTEGTDLLEIK"
     gene            5005..5877
                     /locus_tag="RD451_002750"
     CDS             5005..5877
                     /locus_tag="RD451_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HDT7567935.1"
                     /translation="MLYGAIEAGGTKFVCAIGDEEMTIKERVSFPTTTPEETMPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPKLAWQNFDFIGTMKKEFPIPIS
                     WTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVGGGALQEGRFIEGFSHPEMGHMLVV
                     PHPKDDFAGSCPFHGNCLEGMAAGPAIEKRLGKKGQEVAEDDPYWEIEASYIAQCAYN
                     TTLMFSPDVIIFGGGVMKQRHMLQNVHDAFAKLVNGYVETPELSKYIVTPALEDNAGT
                     LGCLALAREAVLHS"
BASE COUNT         1946 a         1053 c         1085 g         2051 t
ORIGIN      
        1 cgtccaattt cgtaaaacaa ccgtaacagt tgtgtaaaaa tatcatttta gagcatgaaa
       61 aaaggagtgg atttctccac tccaaaaaag tctaactttt gggggtcact acaagttgac
      121 aactcctttt tgtttacaaa tcaattggat atctacaaat tgtattttct aacgaatttt
      181 atagacatta aaaaattaat ttaacgttaa atacttcctc cagaaagtat tgagattggt
      241 aaaatataat ccttatttgt cttttcgcct ttaatttttt tcagaagaat atcaacaata
      301 agacttgcaa tttcatcaat tggttgtctt attgttgtca attgtgggaa aaatttctca
      361 ataaaagagg taccatcgta tccaataatt tttaaatctt ctgggatatt aagtttaagt
      421 tgatgagcaa ttttcatagt gagaatggct gttaaatcat cagaaacaaa aataccatct
      481 ggtttgtgat ttataatagt tgactttatt tccatttcac gacggatagt agacagatta
      541 ttaggaattt tgaaaatttt tccatttgga ttttgaaaag aaaaacctag tgcacgtaat
      601 tctgtgggag aatccgtgtt atcatttcct gtaatcataa tggtattttg acaaccattt
      661 ttttgtaaag tcttagctgc aagttttccc ccttcaaagt tatctgaaga aacaatggaa
      721 acattaggag ctaaatttct atcaaaagca acaataggtg ctctcacacg ctcataatca
      781 gcaattccaa gattatggct tgatgagatt atgccatcaa cttggttggc ttcaagcatt
      841 tcaatgtatt ctctctcttt agcaggatca ttttgactat tgcaaataat cgttttatat
      901 ccatgtttaa ataactctat ttcgagatac tcaatgagtt cagagtaaaa gatattacta
      961 atattaggaa aaataagacc aataagctga ggtgactttc cttgaagtcc acgtgctaaa
     1021 ttatttggtt tataaccaag agttttcata gcttcatgaa ctttttgttt tgttttttct
     1081 gataaatatc ccttattatt aatgacgcgt gaaacggttg ttgggctaac tccagctaat
     1141 tcagcgacat cagttaattt tgctaccatt ttaatatttt aattcaaagt attttccagt
     1201 aggttcgcct gatttgattt gaataccatt ttggtgattt tcagggaata cacgactagt
     1261 aaacactttt tctcctttat taataaaaat ctcaatgatt gagttatcta caaaaatgtt
     1321 agcagttgtt tctttagtat caattgagca ttcacgaatc gtaccaaagt cagtggcata
     1381 ttgaatgcct gctttgctgc gatctaaaat aatttttcct tctttggtat ctacaatcaa
     1441 gctaagtcca tttcctttac tatcagagaa aagaagtaac tccgatttct gatttggagg
     1501 aaaagttagt tcaagctcat aagtattatt tgtttctgct tttgctgtaa attgttcaga
     1561 actagcacgt aatgatgtaa tagcttctac tggatattgg taaagtttac catcttttat
     1621 tgaaagttct tttacaagac tcattgctcc ctgataatca tacttatcag ttggataatc
     1681 gatatcaggt agtccaatcc aactgacaat cagagcacga ccatcaggag tattgaatcc
     1741 ttgagtcgca tacgcttcaa atccataatc aagattttga atttctgaag cgcccacaag
     1801 ttttactttt tctatgtcaa gcgattgaca gatcttaaaa gtattcggat agatattccc
     1861 ataatttagc tcagatttat ccaacccttg aggacaataa atgagaacag gttttttgtc
     1921 tacaaatact agatttggac actcaatcat gtattctgaa ccagtgccgc caaaatcaag
     1981 gttgccaact tcctcccatg tttccacgtt attgtcatcc gctttgtaaa gtttgataaa
     2041 gcctgatttt tctaaatttt gtgctccaac aatcgcatac aattgtcctt cataattaaa
     2101 catttgtgga tcacgaaaat gatcagttac atcagcaggt ttatgaataa gaacattctc
     2161 acctttcgta atgttgtagt ctttatccat ccatgctccg atttgaagtg tatcacgttc
     2221 ccaattttca tttcgaacgt ttcctgtata gagtaagaat agattcccct ctatttcata
     2281 tgcagaaccg gaataagcgc cgtggctatc tcgttttgtg tctggaagaa gttctgctcc
     2341 tgttacatga aaatgaacta aatcatctga ttcattgtgt acccattctt tcaacccatg
     2401 agcagctcca aatggccaat tttgataaaa aagcgtatat tttccgttaa aaaaagaaaa
     2461 accattagga tcgtttaaca atcctgtttt aggttcgata tgatagctag cacgccaagg
     2521 tgatcgtttt acattatcct taattttatc catctcatct ttagtccaat cagaataagc
     2581 acgatatcgt atttctcgag gtaagttcat attttactcc ttcaatttat ctttttacaa
     2641 ctagtatggt aaacgttttc cgttgaaaaa tcaatcattt catttaaaaa aataaactat
     2701 atgacaaacg tttgacatat ttttaagata tgctaaaata aatttgcatt tcagtgaacc
     2761 gttttcacgt aaaaataaaa aaggagtgat tcgaatgaat tacagtaaag tagcttccga
     2821 cgtaatacaa gcggtcggaa aagataacct tattgcagct gcacactgcg ctacacgtct
     2881 tcgtctcgta ctaaaagatg acacgaaagt gaatcaaaaa gctttagacg aaaatccaga
     2941 tgtgaaaggc acatttaaaa ttgatggaca atatcaagtg attatcggtg caggtgatgt
     3001 taatttcgtt tatgacgaac ttatcaaaaa aactggactt tcggaaattt caacagatga
     3061 tttaaaacaa attgctagta aagataaaaa attcaacccc attatggcat taattaaatt
     3121 attatcagat atttttgttc caattatacc tgcccttgtt gcaggtggtt tattaatggc
     3181 attacaaaac tttttaacag ctgctggact ttttggacca aaatcaattg aagaaatgta
     3241 tcctgcgatt gaaggtattt cctcaatgat ccaactgatg tccgctgcac cattcatgtt
     3301 cttaccaatt ttagtaggta tttcagctgc taaacgtttt ggagcaaacc aatttcttgg
     3361 tgctgcaatt ggtatgatca tgacaacacc agatcttggt ggctcaactg aatattggaa
     3421 tatttttggt tatcatgttt cacaaacaaa ctatgcttat caagttattc cagttttagc
     3481 agctgtttgg atattatcta tattagaaaa attctttcat aaaaaattgc catcatctat
     3541 tgactttaca ttcacgccat tattatcagt aatgattact ggatttttga ctttcacagt
     3601 tattggccct gtaatgttat tgttgtctaa tggaattaca gacattattg tttggctata
     3661 taacactact ggatttattg gaatgggtat ttttggagga acatattcac ttatagtcat
     3721 gactggttta catcaatcat ttccagctat tgaaactcaa ttactttcag cgtggacaaa
     3781 tggtatcgga catggagact ttatctttgt agttgcatct atggcaaacg ttgctcaagg
     3841 tgctgcaaca tttgccattt ggttcttaac taaaaattct aagacaaaaa gtcttgcttc
     3901 ctctgcgggt gtctcagcac ttcttggaat tacagagcct gccttgttcg gagttaactt
     3961 aaaataccgc tttccattct tttgtgcttt aattggttca ggaattgcta cagcagtagc
     4021 aggattactt aaagtagttg ctgtttcact tggttcagca ggtttcttgg gatttctttc
     4081 aattaatgca acatctattc cattttacgt attgtgtgaa ttgattagct ttgtagttgc
     4141 ttttgcaatt acttacttct acggtaaaac aaaagctgct ggtatcttta aagcagaaga
     4201 aattgctgaa caaacaccag ttaattcttc aaaagtagca acaacagatc caatatctac
     4261 tgatgttgaa tcaacacaaa caaaagtttc atcagaaaca attgttagtc ccatttctgg
     4321 taaagtgatt agtctttctt cagtaaatga tccagtcttt tcatcagaag ctatgggaaa
     4381 agggattgcc attaaaccaa atggaaacac ggtccattct ccagtagatg gtactattca
     4441 actcacgttt gaaactggac atgcttatgg tattaaatca aataatggtg ctgaagttct
     4501 aattcatatt ggtattgata ctgtatcaat gggaggaaaa ggatttacac aaaaagttac
     4561 tactaatcaa aaagttagaa aaggcgatat tcttggagca tttgaccgtt caatgattga
     4621 gaaagaaggt cttgatgata caacaatgat tattgtgacc aatacttcgg attattcaga
     4681 agtaaatata gtagctgaaa atacagtcac tgagggtact gatttacttg aaatcaaata
     4741 aatatatttc cctgagtaaa gatggaattt tctttccaaa atcaaataat atagattaat
     4801 caaatatttg agaataacat tttatttaat cttttcatat atcaattgta tgaaaaatta
     4861 ttagaatttt aaaaaatgat aaaaattcaa aaagaaaaaa tagtagttat ttacttgtca
     4921 tgttactaaa taaaaaaata atttaaatat gatatatagt catttattta gtgatttcat
     4981 tctaaaataa agggagaaat gtctatgcta tacggtgcaa ttgaagcagg cggcacaaaa
     5041 tttgtgtgtg ccattggcga tgaagaaatg acgatcaagg aaagagtgag ctttccgaca
     5101 acgacacctg aggaaacaat gcctttagtc attgacttct tcaaacaata ccaagcagat
     5161 ttagcaggga ttgggattgg ctcatttggg cctatcgata tccatcgcga ttccgccact
     5221 tatgggtaca ttacctcgac cccgaaattg gcatggcaaa attttgattt catcggtacc
     5281 atgaaaaaag aatttccgat cccgatttct tggacaacag atgtcaatgc ggctgcctat
     5341 ggtgagtatg tcttcggcag tggcaaagga ttgagcagtg tcgtttacta tacgatcggt
     5401 acgggtgttg gcggcggtgc cttacaagaa gggcgcttta tcgaagggtt tagtcatcca
     5461 gaaatggggc atatgctcgt cgtccctcat ccaaaagatg actttgctgg cagctgtcca
     5521 tttcatggca actgtttaga agggatggcc gctggacccg ccatcgaaaa acgcttaggg
     5581 aaaaaaggac aagaggttgc agaagatgat ccttattggg aaatcgaagc ctcctatatt
     5641 gctcaatgtg cctacaatac aaccttgatg ttttctccag atgtgatcat ttttggcggt
     5701 ggtgtgatga aacaacgcca tatgctgcaa aacgtccacg acgcatttgc aaaattggtc
     5761 aatgggtatg tcgaaacacc tgagttaagc aaatatatcg tgaccccagc attagaagac
     5821 aacgctggaa cgctcggttg tttggcattg gctcgagaag cggtcttaca ttcataaacg
     5881 aaaaaaggct cttcgacatt tagtgttggt agagaaagat acaactgaaa atttagtcat
     5941 aaccagttag gcagagtgct taactggttt ttgttttact tggaagatca agccttgaat
     6001 gagataaatt cttgctcgaa agttatggaa atttcgatag ccgtaggcca cttgtattgt
     6061 gcaatagttt tttacaaaaa aaagggggtg cggatatttt tttggacctt tttaacaaat
     6121 atatctttgc ttctt
//
LOCUS       DAPBAF010000090         5877 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.094, whole genome shotgun sequence.
ACCESSION   DAPBAF010000090 DAPBAF010000000
VERSION     DAPBAF010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5877)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5877)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5877
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.094"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            641..1375
                     /locus_tag="RD451_002751"
     CDS             641..1375
                     /locus_tag="RD451_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDT7567936.1"
                     /translation="MQNTFQSKSLYYQLVEILKQRIENSMVAHDKLPSERELTSFYGV
                     SRTTVRLALQELEKMGYIYRQHGKGTFVSELRTNATDLAGAYSFTEQMRAMGKHPETK
                     ILAFKKIEATKYLASHLNVQLGEPLFQLDRLRLADDLPMMIEKSYLPVKLFMSLSQEI
                     LFLKPLYNLFSENFNQIVRLADEEFYASIVQKEDSELLNIPEGSPVLHLVRSTYNLEN
                     EVIEFTLSVARADKFHYKIRHLRSTN"
     gene            1391..2560
                     /locus_tag="RD451_002752"
     CDS             1391..2560
                     /locus_tag="RD451_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDT7567937.1"
                     /translation="MFMFSKEELRKLGAENTTREIRQQPELWHETFDRYQETVADLDR
                     LFTDAKQHAGERPIRVIFTGAGTSQYVGDTLIPFLTSQGNTNQFIFQSIGSTDIVATP
                     KEYLIPDETTILVSFARSGNSPESLAAVKMANQLVNKIYHIVITCAPDGLLATQMPTK
                     KENLVLLMPNKANDAGFAMTSSFSCMTLTALLIFDQASNQQKERYVHQLSRLGEEVIQ
                     RESEIQGYLASDFHRIIYLGSGSLGGLTREAQLKVLELTAGKIATVFDTSLGFRHGPK
                     SFVNEQTLVFLFVSNDSYTQKYDVDMLEEIKNDGIAQRVVGIGQKGSLFSGDSFELVA
                     DSLLPDGYLALADIMVAQTIALLCSVKVGNTPDTPSPSGTVNRVVKGVTIYPYEK"
     gene            2576..3571
                     /gene="lacD"
                     /locus_tag="RD451_002753"
     CDS             2576..3571
                     /gene="lacD"
                     /locus_tag="RD451_002753"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HDT7567938.1"
                     /translation="MLEWSENKRQAMERLSTPEGIITALAIDQRGALKKMMSALGMEA
                     TKEKIEQFKTLISQELTPYASAILLDPEYGLPAAQKRAAASGLLLAYEKTGYDQTVPG
                     RLPDLLSDCSVLRLKELGADAVKFLLYYDYEEAEEINRQKQVFVERIGSECMAEGLPF
                     YLELLSYDAKNVDTKSLSYAKAKPRKVIEMMKEFSKTQYKVDVLKVEVPVNMSFVEGN
                     ATGEIAYTRQEAAAYFKEQSDATDLPYIFLSAGVSAALFMETLRFAKHAGARFNGVLC
                     GRATWKDAVAPFVEKGEAATLEWLTEQGTQNIRQLNEVIRETAIPWYEKVSESTC"
     gene            3650..4576
                     /locus_tag="RD451_002754"
     CDS             3650..4576
                     /locus_tag="RD451_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HDT7567939.1"
                     /translation="MNKRLLDYSASDFLKAKPMELKQAILASEGRTIMAENVPSSCPY
                     MGKSVTNAELERAAGADLILFNALDLFNPQISGVPLTLKENPIIWIKKALGRAIGVNL
                     EPVDKEVLMSENRTEISSGRIVSPETLKKANELGFNFICLTGNPGTGVSNRTIEKAIT
                     LSKSIFNGLIIAGKMHGAGVDEPIMNLDIAKRFIKTGVDILLVPAPYTVPYFMESDLR
                     GIVDYIKDFNRNKSIEEKVLVLTANGTSQDSSDQETIKKIALASKACGADIQHIGDSL
                     NGICLPENIFALGQAIRGYRHQIIMLGKSNYR"
     gene            4595..5845
                     /locus_tag="RD451_002755"
     CDS             4595..5845
                     /locus_tag="RD451_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDT7567940.1"
                     /translation="MIDKVQKIAAKISNQRHLLALRDSMAAVMPLIIIGSFFMLLANF
                     PIEGFTKWLSEIGVQSFLNKASDSTFGIIGLAVTYSLGHNLAKTYGVDSLSAGLLSLS
                     GYVLLTPLLDADGSIGFPTKYFGTSGLFVGIIVALVSTEIFRWFVLKNITIKMPASVP
                     PNVSRAFVAIIPGFFVVLLWFIVVVICYKLGIENVHALIADTLAKPLSLLTKTLPGII
                     LVILIQCFFWMFGIHGAQVTGPIIEPLLLQNSDVNRIAYQAGKELPNIITYEFLYNFV
                     FSGGAGCLFALAILTFFFSKSQENKTLGKLSIAPVSFQVAEPLLFGFPTILNIKMLIP
                     FVTAPVVTTLITYFSMSMGLVAKPVGATIPWTTPPIIAGFLASGGRISGAVIQVITIA
                     INVLIYYPFFKLDDNAKLKSEKND"
BASE COUNT         1966 a          955 c         1205 g         1751 t
ORIGIN      
        1 gtttgaaaaa tgctatttcg aggtagaagg atattatata agcacggttg actaaacgaa
       61 gtgataataa aaaaagttat tcaagaataa gaaaaattat gatacgaatt cagataaact
      121 ggagaataca gagaccttta aaagggataa gaaacaacat aaattcctct taagagagaa
      181 cgaaaggaca aagccagcaa cttgatacac gagctagtat tagaggaatt tattctcata
      241 gactcccttt tgaatacgtt tcaactttaa ttttcatgtt cataaatgat ttgaaaccaa
      301 agcaaatgcg ttgcactttt cctccgtctt ccgaaaatcg ttcaattcac tggtaagtag
      361 tcatttgata gtttgaggca aattgttgat tgatgaaggg taggagctaa aaaaagatac
      421 cagttgaaga gagaaaaaga aaaaaataga gggtgttctt gaatgaaaaa agttggaaaa
      481 ttatttttca tttcctttta ttcctattaa agtcagtgat gtcaatcata ttaacaagac
      541 taaaaatgaa aataaaagaa agattgttct tagtattgac tcataaaaaa taccactact
      601 atacttacat tgtggttata gccagttagg agagacatcg atgcaaaata cctttcaatc
      661 aaaatcactt tattatcagc tggtagaaat attgaaacaa cgaatcgaaa acagtatggt
      721 cgctcatgac aagctgccat cagaaagaga gttgaccagt ttttatggcg ttagtcgcac
      781 gacggtgcga ctagcattgc aagaactgga aaaaatgggc tacatttatc gacaacatgg
      841 aaaaggaacc tttgtttcgg aattaaggac aaatgcgact gatctagctg gcgcatatag
      901 ttttaccgaa caaatgcggg caatgggcaa acatcctgaa accaagatat tggccttcaa
      961 gaagattgaa gcaactaaat atttagcgag tcatctgaat gttcaactag gtgagccttt
     1021 atttcaatta gaccgattgc gcttagctga tgatttgcca atgatgatcg agaaatccta
     1081 tttgccagtg aagctattta tgtccctttc tcaagaaatt ctatttctga aacctttata
     1141 taatttgttt tcagagaatt tcaatcaaat cgtacggttg gctgacgagg aattttatgc
     1201 cagcattgtc cagaaagaag atagtgagtt gctaaatatt ccagaaggat caccagtgct
     1261 ccatttagtt cgctcaacct ataatctcga gaacgaagtg attgaattta cattaagtgt
     1321 agcgcgggct gataaatttc attataagat caggcatctg cgttccacta actgaattgg
     1381 aggaaagaaa atgtttatgt tctcaaaaga agaactacga aagctaggag cagaaaatac
     1441 tacccgagaa attcgacagc aaccggaact gtggcatgag acgtttgacc gttatcaaga
     1501 aacagttgca gatttagatc gtttgtttac ggatgcgaaa caacatgctg gagagcgacc
     1561 aatccgagtc atttttacag gggccggaac ctcgcaatat gtgggagata cactaattcc
     1621 gtttcttact agtcaaggaa atacgaacca gtttattttt caaagtattg gttcgaccga
     1681 tatcgttgct acgccaaaag aatacctgat tcctgatgag acaacgatct tggtctcatt
     1741 tgcccgtagt ggaaatagtc cagaaagtct agccgcagtt aagatggcca atcagctggt
     1801 caacaagatc tatcatatcg tgatcacctg tgcaccagac ggattattgg ctacacaaat
     1861 gcctacaaaa aaagaaaatc tagttttact aatgccaaac aaagccaatg acgctggttt
     1921 tgctatgaca agcagtttca gctgtatgac gctgactgcg ctacttattt ttgatcaagc
     1981 aagcaatcag caaaaagaaa gatatgttca tcaattaagc cgactaggag aagaagtcat
     2041 ccaacgagaa tcagagatcc aagggtatct ggcatcagac tttcatcgca tcatttactt
     2101 aggttcggga agcttaggcg gattgactag agaagcgcaa ttaaaagttc tcgagttaac
     2161 tgctggaaaa atcgcaaccg tatttgatac atctttagga ttcagacatg gtcccaaatc
     2221 ttttgtcaat gagcaaacat tggttttcct gtttgtcagc aatgactcat atacgcagaa
     2281 atacgatgta gacatgctgg aagaaatcaa aaatgacggt attgcccaac gcgttgttgg
     2341 aattggtcaa aagggttcat tgtttagtgg tgattccttt gaattagttg cagattcgtt
     2401 actgccggat ggctatcttg ctttagcaga tatcatggta gcccaaacga tcgcattact
     2461 ttgttcggtg aaggttggta atacaccaga tacaccatcg ccaagtggaa cagtcaatcg
     2521 tgtggtcaaa ggcgtaacga tttatccata tgaaaaatag gaaagagtgt gaagcatgtt
     2581 agaatggtcg gaaaataaaa gacaagcaat ggaacgtcta tcgacgccag aaggcattat
     2641 taccgctttg gcgatcgatc agcgaggcgc gctgaagaaa atgatgtcgg ctttagggat
     2701 ggaagcgaca aaggaaaaaa ttgagcagtt taaaacacta atttcccaag aattgactcc
     2761 ttatgcctca gcaattttat tggatcctga atacggactg cctgctgcac agaagcgtgc
     2821 agcagcgagc ggtctgctgt tggcatatga aaaaactggt tatgatcaaa ccgtacccgg
     2881 ccgcttgccg gatctgctgt cggactgttc agttctgcga ttgaaagagt taggtgcgga
     2941 tgcggtgaaa tttttactgt attacgatta tgaagaagca gaggaaatca atcggcaaaa
     3001 gcaagttttt gttgaacgaa ttggaagcga atgcatggct gaaggactgc cattttattt
     3061 agagttattg tcatatgatg ctaaaaatgt agatacgaaa tcgctttcct atgccaaagc
     3121 aaaaccgcgc aaagtgatcg aaatgatgaa agaattctcg aaaacccagt ataaagtaga
     3181 tgtcttaaag gttgaagtac cagtaaacat gtcatttgtt gaaggaaatg caacagggga
     3241 gatcgcctat acacgtcaag aagctgccgc ttattttaaa gaacaaagcg atgcaacaga
     3301 tttgccgtat atcttcttaa gtgctggggt atcagcggca ttattcatgg agacattgcg
     3361 ttttgccaaa catgctgggg cacgattcaa cggtgtactc tgtggcagag caacttggaa
     3421 agatgcagtc gctcctttcg ttgaaaaagg agaagcggca actttagaat ggctgacaga
     3481 acaagggaca caaaacattc gtcaattgaa tgaagtgata agagaaactg ccatcccatg
     3541 gtatgagaaa gtaagtgaaa gcacttgtta atgtttctaa tatattagta gtgataagag
     3601 atatgtgtga ttataattta tcattattga aactgggagg atattttata tgaataaaag
     3661 attgttagat tattcagctt cagatttttt gaaagctaag ccgatggaat taaagcaggc
     3721 aattttggct tctgaaggta gaacaattat ggcagaaaat gtgccaagta gctgtcctta
     3781 catgggaaaa tcagtgacaa atgcagaatt ggagagagct gctggagctg atttaatttt
     3841 gtttaatgca ctagatcttt ttaatcctca aatttcaggt gtacctttaa ctctaaaaga
     3901 gaatccaata atctggatta aaaaagcttt aggaagagct attggtgtaa atttagaacc
     3961 tgtagacaaa gaagttttga tgagtgaaaa tcgaactgaa atttcaagtg gtagaatcgt
     4021 ttctcctgag actttaaaaa aggcaaatga attaggcttt aattttattt gtttaactgg
     4081 aaatccagga acaggagtat ctaatagaac tattgagaaa gcaataacat tatccaaatc
     4141 aatttttaat ggattaatta tcgctggaaa aatgcatggt gctggtgttg atgaaccaat
     4201 tatgaactta gatatagcaa aaagatttat taaaacaggt gtagatattt tattagttcc
     4261 tgctccatac actgttccgt atttcatgga aagtgatttg cgaggaatcg ttgattatat
     4321 aaaagatttt aatagaaata aatctattga ggaaaaagtt ctagtactaa cggctaatgg
     4381 aacaagccaa gactcttctg accaagaaac tattaaaaaa attgcattag catcaaaagc
     4441 atgtggagct gatattcaac acatagggga ttctttaaat ggtatttgtc ttccagaaaa
     4501 tatttttgct ttgggtcaag caattcgggg atatcgtcat caaattatta tgttaggaaa
     4561 atctaattat cgttaattaa ggaggaaatg aaagatgatc gacaaagttc aaaaaatagc
     4621 tgcaaaaatt agtaatcaaa gacatctact agctttaaga gacagcatgg ctgcagttat
     4681 gccattaatc attattggtt ccttttttat gttattagca aatttcccga tagaaggatt
     4741 tacaaaatgg ttatctgaaa ttggagtaca atcctttttg aacaaagcat cagattcaac
     4801 atttggtatt attggattag ctgttaccta ctctttggga cacaatctag caaagactta
     4861 tggtgtagac tcattatcag caggattatt atctttgagt ggatatgttt tacttacacc
     4921 tttattggat gcagatggtt ctataggatt tccaacaaaa tactttggta cctcgggtct
     4981 ttttgttggt attattgtag cacttgtatc tacagaaatt ttccggtggt ttgtacttaa
     5041 aaatattaca attaaaatgc cggcaagcgt tccaccaaat gtaagccgag ctttcgttgc
     5101 tattattcct ggcttttttg tcgttctact atggtttatt gttgttgtaa tttgttataa
     5161 acttggaatt gaaaatgttc atgctcttat tgcagataca ctcgcaaaac cactatcttt
     5221 actgacgaaa actttaccag gaattatatt ggttatactt attcaatgtt tcttttggat
     5281 gtttggtatt catggtgcac aggtaacggg gccaataatt gaaccgttat tattgcaaaa
     5341 ctctgatgta aatagaattg cttatcaagc tggaaaagaa cttcctaaca ttataactta
     5401 tgaattctta tataactttg ttttttctgg tggtgcaggt tgtttatttg cacttgccat
     5461 tttaacattt ttcttttcaa agagtcagga aaataaaact ttaggtaagt tatcaatcgc
     5521 tccagtaagt tttcaagtag cagagcccct tctatttggg tttccaacta tattaaatat
     5581 aaaaatgtta attccatttg taactgcacc agtagtaaca acattaatta cttatttttc
     5641 aatgagtatg ggattagttg caaaacctgt aggagcaaca atcccatgga caactccacc
     5701 gataattgcc ggatttttag cttctggtgg acgaataagt ggtgcagtga ttcaagtaat
     5761 aacaattgca ataaatgttt tgatatacta tccattcttt aaattagatg ataatgccaa
     5821 gctaaaaagc gaaaaaaatg attagaacta cctatatgtt tctaactgta gttaagt
//
LOCUS       DAPBAF010000091         5823 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.095, whole genome shotgun sequence.
ACCESSION   DAPBAF010000091 DAPBAF010000000
VERSION     DAPBAF010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5823)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5823)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5823
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.095"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            41..1000
                     /locus_tag="RD451_002756"
     CDS             41..1000
                     /locus_tag="RD451_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HDT7567941.1"
                     /translation="MTYNHLTPTELVMIEAYFNQSQPVSKVANLLQRSRQTIYKVYRF
                     LKSGGSAMSYYKQYKKNKRNCGRHPIVLPDEQQEYIQKKVVQGWAPDVLIGRAEFPIA
                     CSVRTLYRMFKDKTFDTHDLPMKGKRKPNGHKEKRGKQGFRRSIRDRKTDYTQFDHEF
                     GHLEGDTIVGGKHKSAVITLVERLSKVIITLKPEGRQAKDIENRLNQWFRCVPKNLFK
                     SITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNG
                     VSETFIQSVASKRNHIPRKSLHYRTPMEVFLSYVTKDDLSNLI"
     gene            complement(1238..1780)
                     /locus_tag="RD451_002757"
     CDS             complement(1238..1780)
                     /locus_tag="RD451_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDT7567942.1"
                     /translation="MNIVEEKFVQETKQADIDHHKPTAGAMVGHVLANFKLEEMKLIQ
                     AQLYVLGTSSQELSTLFSEYADQEARWFNKISHELVIENEIVPSTLEEVMRYGKIYEH
                     GQNKYLPASTMLENFAKDFDFQNVFITRAIKLAEKEEKYGLQQLLVELLSFNKEIIYQ
                     VQRLQGKTVRQDLDEEDDDD"
     gene            complement(1785..2012)
                     /locus_tag="RD451_002758"
     CDS             complement(1785..2012)
                     /locus_tag="RD451_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HDT7567943.1"
                     /translation="MKKIIMQLDTLACPSCMQKIEHAVSQQPGVSNTKVLFNASKIKA
                     NFDPDEVHPEQLAAVVEKLGYEVQSAKVKEA"
     gene            complement(2091..3971)
                     /locus_tag="RD451_002759"
     CDS             complement(2091..3971)
                     /locus_tag="RD451_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HDT7567944.1"
                     /translation="MKLQKWIQEHRNHITALSAVLIIFGFIGKFTGFVLFYNIALAIA
                     SIIAVIPIMIHAYQAVKVKVISIDLLVTIAVLGAFMIGEYKESAIVTFLFLFGSYLEQ
                     KTLTKTRESIKALTEMAPSTASVVQEDGTTEEVEIDDVEEGDIVLVKTGGAIPVDGRV
                     IDGKGYADEAAVTGESRQVVKISGDEVFSGTILADGYVTIEATKVGDDTTFAKIIELV
                     EEAQDTKSHAEKFIDRFSQYYTPTVLLIALVVGLISRDFRLAITVLVLGCPGALVIGA
                     PVSNVAGIGNGAKRGILVKGGEAMDTFSKIDTFVFDKTGTLTKGTTAVSTIKNYTEDE
                     GDSLALVARLETLSDHPLGRAVIHYAQEKDIDFQQLAVKDNQTIKGQGITAEIDGHTV
                     CAGNTKLIAAHKLSLTPKQVQDLHQLQQTGSSVIIVAIDKKITQIIGVSDVIRPEVAE
                     QLAKLKQAGAKQLVMLTGDNQMTADYVADMLGIDEVHAELLPDEKVQFVKKYQEQGLR
                     VAFIGDGINDSPSLAAADIGIAMGSGTDVAIETSDVVLMQSNFESLVHAYRLAKKTVL
                     NTRENVVIAIGVVLFLLNGLFAGFIYMASGMFVHEASILIVIFNAMRLLYFGHESKEE
                     KS"
     gene            complement(4160..4774)
                     /locus_tag="RD451_002760"
     CDS             complement(4160..4774)
                     /locus_tag="RD451_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7567945.1"
                     /translation="MKLTFKPLEKKDYKKAIYFAVEGMNFERYMENELLLNLYGRYFL
                     YMELNRATQILALYAEDELAGVLLAEIKGEKKKHRSFGQQIYVKIFDFLQNIFAKESK
                     GAYETANEQMLAAYLKKHSPDGEIIFLAANPDLKTKGIGTKLLTEFEKREKGKEIFLF
                     TDSGCTYQFYERRGFERLKEKISKIKILDKEIDLRCMLYRKIIQ"
     gene            4916..5476
                     /locus_tag="RD451_002761"
     CDS             4916..5476
                     /locus_tag="RD451_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDT7567946.1"
                     /translation="MKKTDRRVKKTEKALAETLSTLLVNKKIQAITIRELTETADVHR
                     STFYTHYKDIYDLYDQLESNFFRDLNEILSYDPAHSYEELYTRLIDYVYANTFLYRLF
                     ILNHGDISFQKKVKQVIEENYLNIWLYEDKKTIITEEMRFFTTYHVQGCLSVLNRWVE
                     SNYKYSKKELLELLQKLNDHIEKIMP"
BASE COUNT         1811 a         1170 c          938 g         1904 t
ORIGIN      
        1 aaaatagttc cgacgaaaga attataagga gtgagtacaa atgacctata accatcttac
       61 accaactgaa ctcgtaatga tagaagctta tttcaatcaa tcacaacctg tttcaaaagt
      121 agccaatctg ttacaacgtt ctcgacaaac tatttataag gtctatcgtt ttcttaaatc
      181 tggtggaagc gcaatgagct actataaaca atataagaaa aacaaacgta actgcggaag
      241 acatccgatt gttttacctg atgagcaaca ggaatacatt caaaaaaagg ttgttcaagg
      301 gtgggctcct gatgtcctta ttggtcgagc agagtttcct attgcttgtt cggtacgcac
      361 actgtatcga atgtttaaag ataaaacctt tgacactcac gatttaccaa tgaagggaaa
      421 aagaaaacca aacggtcata aagaaaaaag aggaaaacaa gggtttcgcc ggtcaatccg
      481 agacagaaag acagactata cccagtttga tcatgaattt ggtcacctgg aaggtgacac
      541 tatcgtgggt ggaaaacata aaagcgcggt catcacatta gttgaacggc tatctaaagt
      601 catcattacc ttgaaacccg aaggcagaca ggctaaagac attgaaaata ggctgaatca
      661 atggtttcgt tgtgtcccaa aaaacttatt taaatccatc acatttgatt gtggaaaaga
      721 attctcaaat tggaaaaaga ttagtaatac caacgatatt tcaatttatt ttgcggatcc
      781 aggaacacct tctcaacgag gattgaatga acattcaaat ggcttattac gtaaagatgg
      841 tttgtataaa gctatggatt ttaatggtgt atctgaaacc tttatccaat cggtggcatc
      901 gaaacgaaat catattccta gaaaatcatt acactatcgg acaccaatgg aagtattttt
      961 gagttacgtc acaaaagatg atttgtctaa cttaatttga caaacgaaaa attaaaaaac
     1021 tcctttcgat tactcccact tctttattct atcaaataag caatgtgatt ttattgattt
     1081 ttcgtatttt ctcatcaatc tttcaaatct tctaaaaact gagaagcacc cgctgatgtt
     1141 gtctgtaata catcagcggg tgcttctttt attttaatct tcgtgatttt ccaatttacc
     1201 tcacgcttta tatttgtatt tgaagaaaca tagactttta gtcatcatcg tcttcctcat
     1261 ccaaatcttg tcggacagtt tttccttgga gtctttgtac ttggtagatg atttctttat
     1321 tgaaacttaa aagttcaaca agcaattgtt gcaagccata tttttcttct ttttcagcta
     1381 atttgattgc ccgtgtgata aagacatttt ggaaatcaaa atcttttgca aagttttcca
     1441 acattgttga ggctggtaaa tatttgtttt gaccatgttc gtaaattttt ccataacgca
     1501 tgacttcttc taaagtagac ggaacgattt cattttcaat cactaactca tgagagattt
     1561 tattgaacca tctcgcttct tgatcagcat attctgaaaa aagggtactt aattcttgcg
     1621 aagatgtacc caaaacatac aattgtgctt ggatcaattt catttcttct aatttaaaat
     1681 ttgctaatac atgccccacc atggcgccag cagttggttt atgatggtcg atatctgctt
     1741 gttttgtttc ttgaacaaat ttttcttcca ctatattcat tgatttacgc ctcttttact
     1801 tttgctgatt ggacttcata acctaatttt tccacaactg cagctaattg ttcagggtgg
     1861 acttcatctg gatcaaagtt tgctttgatt ttgctcgcat taaacaaaac tttcgtattg
     1921 cttaccccag gctgttgaga aaccgcatgt tcgatttttt gcatacagct tggacaagct
     1981 agtgtatcta attgcataat aatttttttc atcgtagttc ttccttcctt tttcttgata
     2041 gtcttattct agattacagc ttccataaaa aaattgattc ttatcaagtt ttacgatttt
     2101 tcttctttgc tttcgtgtcc aaaatacaat aaacgcatcg cgttaaagat aacgatcaag
     2161 atactagctt cgtgaacgaa catcccacta gccatgtaaa taaacccggc aaataagccg
     2221 ttgagtaaaa ataagacgac accaatggca atcactacat tttcacgggt atttaaaaca
     2281 gttttcttag ccaagcggta ggcatgaacc aacgattcaa aattagattg catcaagaca
     2341 acgtcactcg tttcgatagc aacatccgtt cctgatccca tagcaatccc gatatcagcc
     2401 gcagccaaag agggagaatc attgattcca tctccaataa aagcaacgcg caatccttgt
     2461 tcttggtatt ttttcacaaa ttgaaccttt tcgtctggta ataattcagc atggacttca
     2521 tcaatgccta acatatcagc tacataatca gcagtcatct gattatcacc tgtcagcatc
     2581 actaactgtt ttgctcctgc ttgtttcaac ttagctaatt gttcagcgac ttctggtcga
     2641 atcacatctg acacacctat gatttgagtg atttttttgt cgattgctac aataatgacc
     2701 gagctgcctg tttgttgtaa ttgatgtaaa tcttgtactt gctttggtgt gagagaaagt
     2761 ttgtgagcgg caatcaattt ggtgttgccc gcacaaactg tatgaccatc aatctcagct
     2821 gtgattcctt gtcccttgat tgtctgatta tctttgactg ctaattgttg aaaatcaatg
     2881 tctttctcct gagcataatg gatcacggcg cgccccagag gatgatcgga taacgtttct
     2941 aatcgagcca ctaaagctaa gctgtcccct tcatcctctg tatagttctt gatagtggat
     3001 acagcagtag ttcctttggt caatgtacca gttttatcaa agacaaaagt atcgattttg
     3061 gaaaaagtat ccattgcttc accgcctttg actaagatgc cccgtttcgc tccattaccg
     3121 attcctgcta cattcgaaac aggcgcacca atgactaaag cgccaggaca accaagaacc
     3181 aaaacagtga ttgctaaacg aaaatcacga ctaatcagac caacaaccaa cgcaataagt
     3241 aaaacggttg gagtataata ctgagaaaat cgatcaatga atttttccgc atgggatttg
     3301 gtatcttgtg cttcttctac taattcgata attttggcaa aggtcgtatc atctccgacc
     3361 ttagttgctt caatcgtcac gtagccatct gctaaaatcg ttccagagaa gacttcatct
     3421 ccactgattt tgacgacttg tcgtgattca ccagtcactg cggcttcatc cgcataccct
     3481 ttcccgtcaa tgactcgtcc gtccacagga atagctccac cagtttttac taagacgata
     3541 tcgccttctt ccacgtcatc gatttccact tcttcagtcg ttccatcttc ttggacaaca
     3601 ctagcagtag atggggccat ctcggtcaaa gccttgattg actcccgcgt tttggtcaat
     3661 gttttttgtt ccagatagct accaaacaaa aacaagaatg taacgatagc tgactccttg
     3721 tattctccga tcataaaggc accaagcaca gcaatagtaa cgagtaaatc aattgagata
     3781 actttgactt tcactgcctg atacgcatgg atcataatag gtatgaccgc aataatagaa
     3841 gctatggcta gagcaatgtt atagaacaag acaaaaccag taaattttcc gataaaacca
     3901 aaaataatca acacagctga taaggcggtg atatgatttc gatgctcttg gatccacttt
     3961 tgtaatttca tctttctccc tcttttcctt tcattcttac gagactaagt atagatactt
     4021 atccatcata aaaaattgac cactatcaag tttagtcaaa aaggcggttt tcttttggta
     4081 gaatacacta caaaaaatag ttagcaagaa gactcactaa aagtgatctt gccaactatt
     4141 gtcgtttcta tcgaaatttt cattgaatga ttttcctgta cagcatacat cggagatcta
     4201 tttctttatc taagattttt atcttgctaa ttttttcctt tagtctttca aatccacgtc
     4261 gttcatagaa ttgatacgta cagccactat ctgtaaaaag gaatatttct tttcctttct
     4321 ctcttttttc aaattctgtt agcaacttgg taccgatgcc ttttgttttc aaatcaggat
     4381 ttgcagctaa aaaaatgatc tctccatctg gcgaatgctt ctttaaatat gctgcaagca
     4441 tttgttcatt tgctgtctcg taagctcctt tactttcttt agcaaatata ttttgtaaaa
     4501 aatcgaatat cttaacatat atttgctgtc caaaagaacg atgtttcttt ttttctcctt
     4561 ttatctccgc cagcaaaaca cctgccaact cgtcctctgc atacaaagca agaatttgag
     4621 ttgctcgatt caactccata tacaaaaaat atcttccgta aagattcagc agaagttcat
     4681 tttccatata tctctcaaag ttcattcctt caacagcaaa atagatagct tttttgtaat
     4741 ctttcttttc taagggttta aaagttagtt tcatcatttc gcctcctcaa cttcaatgat
     4801 tgtgttatac ttacattata atagacacag tgtctactat ctataatcaa tcatctataa
     4861 gtttgtcgat taagcgacag ctttgctttg atatgtcgga taaggagata ggtaaatgaa
     4921 aaagacagat agacgcgtca aaaaaacaga aaaagctttg gctgaaacac tatccacatt
     4981 attagtaaat aaaaagattc aagcaatcac tatacgcgaa ctaacagaaa cggcagatgt
     5041 acatcgttcg actttttata cacattataa ggatatctat gatctatatg atcaattaga
     5101 aagcaacttt tttcgggatc taaatgaaat tctctcttat gatccagccc atagctatga
     5161 ggaactatac actcgcttga ttgactatgt ttacgcaaat acttttttat atcgcttatt
     5221 tatcctcaac catggtgata tttcgtttca gaagaaagtt aaacaagtta ttgaagaaaa
     5281 ctatctgaac atatggctat atgaagacaa gaaaacgatt atcacagaag aaatgagatt
     5341 ctttactacg taccacgtcc aaggttgtct atccgttctc aatcggtggg tagaaagcaa
     5401 ttacaagtac tccaaaaaag aattattaga actcttacag aaactgaatg atcacataga
     5461 gaaaatcatg ccttgaataa aaacatacta agcttagtta agaagaaccg taaccttctc
     5521 gtataacaac tgaatcttat ttagccaaat tgtttactga agattttttg agtaaaattt
     5581 ctataattcc tacttattga aaagtagttt gtagtgctgc ttctccctct ctaagtgata
     5641 tatcttgttg taccaatcaa attcacctca tcattaataa attactttta ggctaattta
     5701 ttacaactta taggttgaag ctgtaaccaa tttatagtca tattatattt ttatcatcca
     5761 gtttattgaa ttcttctcgt ttacctcaat tcattttcaa ggggaatcag ctcatcatct
     5821 aac
//
LOCUS       DAPBAF010000092         5507 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.096, whole genome shotgun sequence.
ACCESSION   DAPBAF010000092 DAPBAF010000000
VERSION     DAPBAF010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5507)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5507)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5507
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.096"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(<1..265)
                     /locus_tag="RD451_002762"
     CDS             complement(<1..265)
                     /locus_tag="RD451_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDT7567947.1"
                     /translation="MMSKNNTNGRNQFAMLTIDDLVPQDHLVRKIDAALDFEFIYPIV
                     EATYSDLGRPSIDPVILIKLVFIQYLFGIRSMRQTIKEVDTNVA"
     gene            complement(255..1454)
                     /locus_tag="RD451_002763"
     CDS             complement(255..1454)
                     /locus_tag="RD451_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002389929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HDT7567948.1"
                     /translation="MARKKRNPDAEKLAESILNTYQPESVEDMQDVLKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKKHDNRRNGYGNKTLKTSFGKVNIDVPRDREASFEPELIP
                     NRKRDVSDIEGKVLSMYARGMSQCDIAATVEDIYGFDISHEMISDITDAVLPELEEWQ
                     ARPLAKCYAFLFVDCMYVTLRENYEAKEYAVYTILGYDLKGNKEILGLWLNQTESKNR
                     WMQVFDELKVRGVEDVFFISMDGVSGLKEGAKAIFPSVIVQRCIVHLVRNALRYLPSK
                     DYKEVCRDMKKFYSASSLNAAHAAFDSFQNRWSHYSGAVDVCKRNFSHVEQLFDYGSA
                     IRKIMYTTNAVESIHSSFRKVTKKGVFSNENAQTVDKVHFMDDVYSLFFYNRFMKTNA
                     RSDSYDV"
     gene            complement(1584..2960)
                     /locus_tag="RD451_002764"
     CDS             complement(1584..2960)
                     /locus_tag="RD451_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7567949.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGGVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            complement(2960..3616)
                     /locus_tag="RD451_002765"
     CDS             complement(2960..3616)
                     /locus_tag="RD451_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDT7567950.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQNKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            complement(3626..4903)
                     /locus_tag="RD451_002766"
     CDS             complement(3626..4903)
                     /locus_tag="RD451_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDT7567951.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEATNNTKRNILFSSGVFTIKEGKNIEENDKNSIIVHEEFAK
                     QNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSENMVFVDY
                     STSQEILNNSENNEIANKILMYSGSAESTDLALNKLKELKIDESKYFVEKDSNAFEES
                     LESVSGIKYIIKVMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKIQIIMQF
                     IFELIFISIPSIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMSNITTLGQ
                     SYLILISIIVLSVVFASSLMLIKKPKEILSKIS"
     gene            complement(4922..5083)
                     /locus_tag="RD451_002767"
     CDS             complement(4922..5083)
                     /locus_tag="RD451_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002608889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDT7567952.1"
                     /translation="MQDKDKCINCGKCKKVCQMNKDSVENCNHLECIRCGRCKNACPV
                     DAISYGVRK"
     gene            5153..5507
                     /locus_tag="RD451_002768"
                     /pseudo
     CDS             5153..5507
                     /locus_tag="RD451_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         1766 a         1009 c          712 g         2020 t
ORIGIN      
        1 aagcgacatt ggtatcgact tccttaatgg tttgtcgcat ggaacggata ccgaataaat
       61 actgaataaa caccaatttg atcagaatca ctggatcgat acttgggcga cctaaatcgg
      121 agtaagtggc ttcgacgatt ggataaataa attcaaaatc aagcgcggca tcaatctttc
      181 gaacgagatg atcttgagga actagatcat caatcgtaag catcgcaaat tgatttctac
      241 cattcgtatt gtttttagac atcatagcta tcactccttg cattcgtttt cataaatcta
      301 ttataaaaga aaagactgta gacatcatcc ataaaatgga ctttgtctac agtctgcgca
      361 ttctcattag agaacactcc cttttttgtg acttttctga agctagagtg aatactttca
      421 actgcattag tagtgtacat gatttttcta atggcgctgc cataatcaaa gagttgttca
      481 acatgagaaa agtttcgttt gcatacatct actgcaccag aataatgaga ccaccgattt
      541 tgaaaactgt cgaaggcagc gtgtgcagcg tttaaagaag aagcactgta gaattttttc
      601 atgtctcgac agacttcctt ataatcctta cttgggaggt atcgtaacgc atttcgaaca
      661 agatgaacaa tacagcgctg cacaatgaca gaaggaaaaa ttgcttttgc gccttctttg
      721 agaccggaaa caccgtccat cgaaatgaaa aaaacatctt ctacaccacg tactttcagt
      781 tcatcaaata cttgcatcca gcgattttta gattctgttt gattgagcca taggcctaaa
      841 atctccttgt ttcctttaag atcatagcca agaatggtgt acacagcata ttctttagct
      901 tcatagtttt cgcgtaaagt gacgtacata caatcaacga atagaaatgc ataacacttg
      961 gctaatggcc gagcttgcca ttcttccaat tcaggaagga cggcatccgt gatatcagaa
     1021 atcatttcgt gggaaatatc aaagccgtaa atatcttcaa cggttgcggc gatatcgcat
     1081 tgactcattc ctcgtgcata catggaaaga accttacctt cgatgtcgga gacatctcgt
     1141 tttctattag gaatcaactc aggttcaaaa gaagcctccc ggtctctggg aacatcaatg
     1201 tttactttac caaagctcgt tttaagcgtc ttattgccat aaccgtttcg tcgattgtca
     1261 tgtttctttg gctctttaga atgggcgtca taccctaaat ggttattcaa ttctccttga
     1321 agcatttttt caaataaggg accaaacaca tcttttaaaa catcttgcat atcctctaca
     1381 gattcgggtt gataagtatt caaaatggat tcagctaact tctcagcatc aggatttctt
     1441 ttctttctag ccatcgtgta atcacctctt gatcttattt tagaaaaata aaaaccgtga
     1501 agcaaccacc cgcctaggat tgatggttac ttacacggtt tatattacac tctcattttt
     1561 ggtgctaaaa agcaccgaaa attttaatta ttgtcaatta ataattcttt tggattcctt
     1621 cttaatatat tgaatgaaga aataatcaat gatacaagaa gtactaaact cataaatata
     1681 actacataaa tcatgaattt aggtaataca ttgatatcta aacttgataa tgtcttgtta
     1741 aatccttcag cttctgcccc accacctaat tggctagatg cagattgttt agctatttgt
     1801 ttagctatat caccagtaac cttattcaat atattattcc caagcttgtc agctgtatat
     1861 tgagctaaga aataggaacc aacgaatgcg gggattgata taaataccat ctcaattagg
     1921 aattgaccaa aaatttctaa ttttgatata cctaatgata gtaatactgc tatttctttc
     1981 tttctagcat tcatccataa gaataataat aatgaaacta caactcctgc aaatattaat
     2041 gagccaaaaa ataatttatt tgaaattgag taaatacctg atatagattg ttgtaatgca
     2101 gggtaatttg atgaactttt aatcaaatta tattctctcc aatttatatc taatttccca
     2161 agatctttta ttacactatc aagattctta tcacctttta caaagaatgt tgcatcttgg
     2221 tatacagctg tatcttcggt attaccataa actttagcag ctgtatgaat atcagtgatt
     2281 aatgtatttt cgtatagttc ttgtgctgca cttactccac cgctattatg cccatcgaat
     2341 agacctttaa tttctacttc tactgtttca tctgcacctt tctcattatc agcatcaaat
     2401 aaattagatt ttatttttat cttatctcca actttaaggt tatttttttc agctaaatct
     2461 ttatgcatta agattttatt tttatcttca ttttctaaat gctttccttc tactaattta
     2521 tatgcttctg atacaaattt tgtttctttt gttgagtcgt taaccccagt taacataact
     2581 gttcttttaa aattctttgc tctttcaggt gattgattcg caagagtctc ttgagtttca
     2641 ataatatcat aatcaactaa atctgcaaca ctgtttattc tttttacata ggagtctata
     2701 ctatctgttt gagatatctt tttaatatct tcacctttta catttccccc acctctaggt
     2761 gttcctggat ttacttgtct atttatctcc atagaaaaac tatttgttat attagcaaat
     2821 gtttcttttg aagctctgtc cgtagcatct ttaatagata aactaatgag acttaaagtt
     2881 gacatagata aaataactaa tatgataatt aatgatttta aactttttct agttacataa
     2941 gcaaatgcat tttttatcat tattcaacct ccaaattcat tttatttact tttttcaact
     3001 ttttaccact tagttctaaa atgatatccg cagaatctgc tacttcctta ctatgtgtta
     3061 caactattac acatttattt ctatctttag ctaatgtctt taatatatta attatttctc
     3121 cagcagtaac actgtctaga ttaccagtag gctcatcagc tagtattatt ggagcatctg
     3181 ataccaatgc tctagcaata gctactcttt gttgctgtcc accagataat ttcataacat
     3241 ttctttttat ttgtttttta tctaaaccta gttcaaacaa gatactttca tctgctgatt
     3301 tatttactaa tctaatattt tcaattggtg ataaataatc tattaaatta tagttttgaa
     3361 atactaaaga tatattattt tttctatgat tactatatcc tttattttgt atatcttcat
     3421 tcttaaacaa tatttttcct gtttgaggtt tatcaagtcc agcaagtaag gaaagaagtg
     3481 tagattttcc tgttcctgac tttcctacta tcgcataaaa cttcccaagt tcaaattttt
     3541 gatttactcc tgacaaaact ttttctttag aatttgcata actatatgct acattcttta
     3601 tttctaatat atccattatt ttctcctaac ttatttttga taagatttct ttaggcttct
     3661 tgattaacat taatgaagaa gcaaatacaa ctgataaaac aataatactt attaatatta
     3721 aataactttg tccaagtgtt gttatatttg acataaaact actattattt attaaacttc
     3781 caccggaaat cattgaatcc tctgagttaa tgaatccatc tacaattact tttagtaata
     3841 catttcctaa aaataaggaa gatattatac ttggtatcga tatgaatatt aactcgaata
     3901 taaattgcat tataatttgt atcttagatg ttccaataga taagaatata cctatttcat
     3961 aaattctttc ccttaaccat agaatcaaga ttaatgaaag aacaaccatc ccacctaaca
     4021 taatagaata agtcattact tttattatat attttattcc actcactgac tctaaagact
     4081 cttcaaacgc attagaatct ttttcaacaa aatactttga ctcatcaatt ttaagctctt
     4141 tcaatttgtt taaggctaag tctgtagatt ctgcactacc agaatacatt aaaattttat
     4201 ttgcaatttc attattttct gaattattta atatctcttg gcttgttgaa taatctacaa
     4261 acaccatatt ttcactaaaa tcagaagata atcctgtata tgtttcctgt tttttaccag
     4321 aaaagatccc tataatttta aatttatgac tttttatttt tccacttttt tcaatatcta
     4381 gtaattcaag atcaacttca tcacctaatt ttagattgtt ttgtttagca aattcttcat
     4441 gaacaataat tgaattctta tcattttctt ctatattttt accttcttta attgtaaata
     4501 ctccactact aaataaaata tttcttttag tattatttgt agcttcgagt gaaacaacat
     4561 tcttaaattc gtcagataaa tcttctctat ttattctttg ttctccgcta actactttag
     4621 catcttttag ttttgctaat ccatcatatt gaattatttt ttcttcaatt tcttttaatt
     4681 tttcaatatc tttaaattga ttaacattaa aatatttacc atcttttttt gttattgata
     4741 ttgaagaatt agaactttca tataaagcct tttctatttc attgcttgat ttcattattg
     4801 ttaaacaaga atacaagcaa gaaagaacta tagttaatat gataaaaatt attaaagttc
     4861 tatttttctt tcttgtaata tatgctatag cattttttat cactttccta actactcctc
     4921 tctattttct tactccataa ctaattgcat ccactggaca agcattttta catcgtccac
     4981 atctgataca ctccagatga ttgcaattct caactgaatc tttattcatt tggcaaactt
     5041 ttttacattt tccacaatta atacacttat ccttatcctg aatcggctac actagactag
     5101 acagaaaaaa taaggtgtgt agaataataa aaaacacact ggaggatttt tcatgccaag
     5161 acgtcaacga agaacctatt caaaagaatt caaacaacaa atcgtcgatc tctatctcgc
     5221 tggtaagcct cgcgcagaaa ttattcgaga gtatgagctt acgccttctt ctttcgataa
     5281 atggatgaag caagcacaat caacgggctc attcaaagaa agagacaact taacaccaga
     5341 acaagcagaa ttgatcgcac taagaaagaa aaataagcaa ctcgaaatgg agaatgatat
     5401 tttaaagcaa gcggcgctga tattcggacg aaaagacaag taattgatgc caacaagcat
     5461 aaatattcca tatcagcgat gtgcaaaatt ctaaatattt ctcgtca
//
LOCUS       DAPBAF010000093         5389 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.097, whole genome shotgun sequence.
ACCESSION   DAPBAF010000093 DAPBAF010000000
VERSION     DAPBAF010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5389)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5389)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5389
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.097"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            <1..486
                     /locus_tag="RD451_002769"
     CDS             <1..486
                     /locus_tag="RD451_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lincosamide nucleotidyltransferase Lnu(B)"
                     /protein_id="HDT7567953.1"
                     /translation="SGYIPDTKAMLIYDETGQLENYLSEISGARPNRLTEENANFLLC
                     NFSNLWLMGINVLKRGEYARSLELLSQLQKNTLQLIRMAEKNADNWLNMSKNLEKEIS
                     LENYKKFAKTTARLDKVELFEAYKNSLLLVMDLQSHLIEQYNLKVTHDILERLLNYIS
                     E"
     gene            1174..1995
                     /locus_tag="RD451_002770"
                     /pseudo
     CDS             1174..1995
                     /locus_tag="RD451_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136908.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase zinc beta ribbon domain-containing
                     protein"
     gene            2138..2362
                     /locus_tag="RD451_002771"
     CDS             2138..2362
                     /locus_tag="RD451_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018579902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7567954.1"
                     /translation="MTTAEMIKELCEQMNISVSELARRIGQTPQNFNKKLQRETVTLD
                     ELKAIADVLGVKFVQAFILPDGDEIKISNE"
     gene            2377..3246
                     /locus_tag="RD451_002772"
     CDS             2377..3246
                     /locus_tag="RD451_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HDT7567955.1"
                     /translation="MVGNVIQIVTEKLSSLPFIEGIVLGGSRARSTHTENSDIDIGIY
                     YNSDSFDLTAINQIATELDDENRNNLVVPPGAWGDWVNGGGWLVINGCHVDLILRDIK
                     RVEQIIKDTEQGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAEIY
                     PTALKKSLMNFFIFEAEFSLMFVKANAGAEDKYYIAGHVFRIISCLNQVLFACNNAYC
                     INEKKAIKLLETFEYKPEKYAERVNHIFEVLGLSLFECYDMTEKLYKEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            3227..3964
                     /locus_tag="RD451_002773"
     CDS             3227..3964
                     /locus_tag="RD451_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDT7567956.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVD
                     FPEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYN
                     EKGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPP
                     ENMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            3997..4905
                     /gene="ant(6)"
                     /locus_tag="RD451_002774"
     CDS             3997..4905
                     /gene="ant(6)"
                     /locus_tag="RD451_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /protein_id="HDT7567957.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKGLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            4902..5150
                     /locus_tag="RD451_002775"
     CDS             4902..5150
                     /locus_tag="RD451_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin acetyltransferase"
                     /protein_id="HDT7567958.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLLTRGAS"
     gene            complement(5153..>5389)
                     /locus_tag="RD451_002776"
     CDS             complement(5153..>5389)
                     /locus_tag="RD451_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HDT7567959.1"
                     /translation="PRKNMDKSEKLDHSLLGKQRKTVETVFSSLEKLGCQNFNSRSVK
                     GLESRFESILLAYSVLLSRAQRRFGGTLRYSLGY"
BASE COUNT         1843 a          809 c         1150 g         1587 t
ORIGIN      
        1 tcaggttata ttcctgatac gaaggctatg cttatttacg atgaaacagg gcaattagaa
       61 aattatttat cagagataag tggtgcaaga ccaaatagac ttactgaaga aaatgctaat
      121 tttttgttgt gtaatttctc taatctatgg ttgatgggaa tcaacgttct aaaaagagga
      181 gaatatgctc gttcattaga actcttatca caacttcaaa aaaatacact acaacttata
      241 cgtatggcag aaaaaaatgc tgataattgg ctaaacatga gtaaaaacct tgaaaaagaa
      301 attagccttg aaaattataa aaaatttgca aagaccactg ctcgattaga taaggtagaa
      361 ttatttgaag cctataaaaa ttctttgcta ttagttatgg atttgcaaag tcaccttatt
      421 gaacaataca acttaaaagt tacacatgac attttagaaa gattgttgaa ttacattagt
      481 gaataggaga gtaacgttat tcacagtatt gggtactgaa aattaacagc atacctcagt
      541 ttttcaaaaa acagcgaagc ctatggatat gttcccgtct accgatagtg caaaaagtgt
      601 cgtggatatg tttccgagaa cggacataca caaatgacat tcattctgtc ctctcaatcc
      661 atgtggaagc agtatgtctg ttaacaagaa aataattatt gttcgtcctg acgagttgtt
      721 agactcgaaa aggataaaca tcatttttag aaccggtagc cgatttttgg ctagcggttt
      781 tttgggctct ttggcaaata gtggtgattg aatctcgcgc tatcctatgg aaaaccgcct
      841 tgtgtgaggg gctgcgagac cgcttcgatc ctagaattgc tgaagcacga atctagcgtc
      901 actcacattt catcttttga cgtagctgag acaaggtgtt tttcttcgat ccgctagtgg
      961 ttaatctctt tttggtgcaa atatggttta gaatttcttt gcatggctta agggagtgga
     1021 gaatcggata ttagtaggat ttacatccac agataaaaat aggcttgatt ttaacagcga
     1081 aactaaaata ccctacttaa atgaagtgat agattagatg ttgggttgtt aggagatgct
     1141 taaaaatcct atgcaatcaa tagtttttag tgtttgttga cttgatccct aaatcgcctg
     1201 agtactaaac gttgagtgtg tctgcttact gtcactagcc agtaagtgag actgtagtta
     1261 atctctcatt ttccccagta ttatgttgaa aatagccatg aagcgattat ttctaaagag
     1321 ttatttttgc aggctcaaga agaaatttat cggagaagta atatctacac aggagaaggc
     1381 aagaacaaaa gaatttatag tagcaagtac gctttaagtg ccatcacctt ctgtggatat
     1441 tgtggcgata tttataggag aacctattgg aatattcatg gcagaaaaga atttgtctgg
     1501 cgatgcgtga ctagaatcga gcagggtccc gaggtatgta agaaccgaac cgtaaaagaa
     1561 gatgaactct atggtgcggt aatgaccgca attaataagc tacttgctgg tggcaacaat
     1621 atgataaaga cactggaaga aaatattcat gctgtgattg gagaaaccac agaataccaa
     1681 atttcagaga ttaataccct actagatgaa aaacaaaaag aactaatcaa gctggccaat
     1741 aaaggtcaag attatgaata cctggtagat gagatcgatg agatgcgaga taagcgtcag
     1801 actcttttag tagaagatgc ctccctcagt ggcgagaacg agcgcatcaa tgagttgatt
     1861 gaatttatcc gcaagaacaa attccgcacc ttagaatatg atgataagct tgtaaggaag
     1921 ataatccaga acgttaaggt ctatgaagac cacttcgtca tagccttcaa accaggtatc
     1981 gaaatggaaa tatgaaaacc agaagtaaat agcccatgac tctgaagtag agttgtgggt
     2041 tttcttttaa ttgctgatta taataatatt ttaatgacta ttgcatttat caaccaaatg
     2101 gtttatgtta ttcttagcat aaacttggag gtgctgtatg actacggcag aaatgattaa
     2161 agaactgtgt gagcaaatga atataagtgt ttccgaactt gctagacgta ttggccagac
     2221 tccacagaat tttaataaaa aattacaacg agaaacagta accttggatg agttgaaggc
     2281 cattgctgat gtgctaggtg tcaagtttgt gcaggcattt attttaccag atggagatga
     2341 aataaaaata tctaacgaat aaaggaggat gtttatatgg taggtaatgt tattcaaata
     2401 gtaacagaga aattatcatc tttgcctttt atagaaggca ttgtattagg gggctcacgt
     2461 gcaagaagca cccatacaga aaattctgat atagatatcg gaatctatta caattcagac
     2521 tcatttgacc tgacagcgat taatcaaatt gctacagagt tggatgatga gaatagaaac
     2581 aaccttgttg tacctcccgg agcgtggggt gattgggtta atggcggtgg atggttagtt
     2641 ataaacgggt gtcatgttga cttgatatta cgtgatataa aacgggtgga acaaataatc
     2701 aaagatacgg agcaaggaat tgttactgcc aattatcaga ccgggcatcc ccatggttat
     2761 ataagtgcta tgtatcgtgg agaattagcg attagtaaaa tactatatgc taagaacgaa
     2821 agcttatgcg aattaaaaaa gcaggcagaa atttacccta ctgctctaaa gaaaagcttg
     2881 atgaactttt ttatatttga agctgaattc tctttaatgt ttgtaaaagc aaatgcgggg
     2941 gcagaggata aatattatat tgcaggccat gtttttcgta ttatttcatg cttaaatcaa
     3001 gtactatttg catgtaataa tgcttattgc attaacgaaa agaaagctat aaaactgctt
     3061 gaaacttttg aatataaacc tgaaaaatat gccgaaagag ttaatcatat ttttgaagta
     3121 ctcggtcttt ctctttttga atgctacgac atgaccgaga aactttataa agaagtgaat
     3181 gaaattgtat cggagataaa taacttttta aacgaggaga gttcagatga aagaaaacaa
     3241 atatgatgat aatatatttt ttcaaaaata cagtcaaatg agtcgctcgc agaaaggact
     3301 ggctggtgcg ggagaatggg agactttgaa aaagatgcta cctgatttta agggtaagcg
     3361 tgtgcttgat ttaggatgcg gctatggatg gcactgtatt atatatgcga tggaaaacgg
     3421 tgcttcctct gtagtaggtg ttgatatttc tcataaaatg ctcgaagtag caaaaggaaa
     3481 aacccatttt ccacagattg aatatgaatg ctgtgccata gaagatgtgg atttcccaga
     3541 ggagagcttt gatgtaatac taagttcgct tgcgtttcat tatgtagcag actatgagaa
     3601 tttaataaaa aagatatata ggatgctgaa ggctggtggc aatttagttt ttacagttga
     3661 acatcctgtt tttactgctc atggaacaca agactggtat tataacgaaa aaggagaaat
     3721 actgcatttc ccggtggaca attattatta tgagggcaaa cggacagcta tgtttttgga
     3781 agaaaaggtt acaaaatatc atagaacact gaccacatat ctaaatacac tgctttcaaa
     3841 tagttttata ataaatcaga ttgtggagcc acagccgcca gagaacatga tggatattcc
     3901 ggggatggcg gatgaaatgc gacgcccaat gatgctgatt gtatcggcaa aaaagaagat
     3961 gtaataatat agaaaaaata aacgaggagt atgtaaatga gatcagaaaa agaaatgatg
     4021 gatttagtac tttctttagc agaacaggat gaacgtattc gaattgtgac ccttgagggg
     4081 tcacgcgcaa atattaatat acctaaagat gaatttcagg attatgatat tacatatttt
     4141 gtaagtgata tagaaccgtt tatatctaat gatgactggc ttaatcaatt tgggaatata
     4201 ataatgatgc aaaagccgga ggatatggaa ttattcccac ctgaagaaaa gggattttcc
     4261 tatcttatgc tatttgatga ttacaataaa attgatctta ccttattgcc cttggaagag
     4321 ttagataatt acctaaaggg cgataaatta ataaagggtc taattgataa agattgtaga
     4381 attaaaaggg acatagttcc gactgatata gattatcatg taagaaagcc aagcgcaagg
     4441 gagtatgatg attgctgcaa tgaattttgg aatgtaacac cttatgttat taaaggattg
     4501 tgccgtaagg aaattttatt tgctattgat cattttaatc agattgttcg ccatgagctg
     4561 ctgagaatga tatcatggaa ggtcggcatc gaaacaggct ttaaattaag tgtaggcaag
     4621 aactataagt ttattgaaag gtatatatcc gaggatttgt gggagaaact tttgtccacc
     4681 taccggatgg attcctatga aaacatatgg gaagcattat ttctatgcca tcaattgttc
     4741 agggcggtat ccggtgaggt ggcggaaagg cttcattatg cctatccgga gtatgatagg
     4801 aatataacaa aatataccag ggacatgtat aaaaaataca ctggtaaaac cggctgcctg
     4861 gatagcacat atgccgctga tatagaagag aggcgggaac agtgattaca gaaatgaaag
     4921 cagggcacct gaaagatatc gataaaccca gcgaaccatt tgaggtgata ggtaagatta
     4981 taccgaggta tgaaaacgag aattggacct ttacagaatt actctatgaa gcgccatatt
     5041 taaaaagcta ccaagacgaa gaggatgaag aggatgagga ggcagattgc cttgaatata
     5101 ttgacaatac tgataagata atatatcttt taacccgtgg tgctagttaa ttttaatatc
     5161 ctaaagaata tctcaaagtt cctccaaaac gtcgttgtgc tcgacttaat agaacactgt
     5221 aagccagtaa tatgctttca aatctactct ctagcccttt aacagaacgt gagttgaaat
     5281 tttgacaacc taatttttct aaggaagaaa aaacagtctc aactgttttt ctttgttttc
     5341 caagtaagct gtggtctagt ttttctgatt tatccatgtt tttacgtgg
//
LOCUS       DAPBAF010000094         5181 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.099, whole genome shotgun sequence.
ACCESSION   DAPBAF010000094 DAPBAF010000000
VERSION     DAPBAF010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5181)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5181)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5181
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.099"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(52..393)
                     /locus_tag="RD451_002777"
     CDS             complement(52..393)
                     /locus_tag="RD451_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HDT7567960.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQTLTDNPIGFGLLPEDDEGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSF
                     EIIEFVADKEE"
     gene            complement(380..709)
                     /locus_tag="RD451_002778"
     CDS             complement(380..709)
                     /locus_tag="RD451_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567961.1"
                     /translation="MIQKFAKMSKTAWIEKLENDLSVMRLAPKKFKREIAEKEAILSV
                     LNAVDDKCPVKISFSDIATIIEGIYYGEVDEEISSIKDLLDFLDKNKDTFIVLTDYEE
                     VTTNEKL"
     gene            complement(1300..1632)
                     /locus_tag="RD451_002779"
     CDS             complement(1300..1632)
                     /locus_tag="RD451_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HDT7567962.1"
                     /translation="MSYTGILSLEDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIS"
     gene            complement(2469..3509)
                     /locus_tag="RD451_002780"
     CDS             complement(2469..3509)
                     /locus_tag="RD451_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HDT7567963.1"
                     /translation="MNDFNYYKSKEIYREKYYQMPKVFFTNEKYMDLSNDAKIAYMLL
                     KDRFDYSVKNNWVDSDDNIFFIFTVEELMKLLQCREGKVSKIKKELEKAGLLKQKRGR
                     VNKRDGKIESMPNLLYLGKPEVTNQDVFKIMEEEDNTDSTVIAKIANTAKPRKINDST
                     VIAKIANTAKSSHIKDSTVIAKIADNLFYSNSIDTNRHIIDTETDQLQNQVLLDNFVD
                     IMQEDSINTFVPENVLNLIKTFSSSYSEAQQTVQTIHNAKKKAEELEQTIVVYEELES
                     YGIDADKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFVEKAIAAKLANEQRETFN
                     ELPTVSTENWLE"
     gene            complement(3858..4184)
                     /locus_tag="RD451_002781"
     CDS             complement(3858..4184)
                     /locus_tag="RD451_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567964.1"
                     /translation="MAEDNRSQAAVSRLLGNKNKKNYKPKEVEEIELTKKNISKVIKD
                     QGSSVRTADSIRINPILMSALKYWTTIAESDKSKPDVIEDALLKSIPEEYLIEGYKLA
                     KKQNKI"
     gene            complement(4171..4974)
                     /locus_tag="RD451_002782"
     CDS             complement(4171..4974)
                     /locus_tag="RD451_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HDT7567965.1"
                     /translation="MGDILMARILSVANQKGGVSKTTTSVNLAACLKFVYGKNVLLVD
                     IDPQGNATDNVGFDIDGTNQPTIYEVLKGEADITDAILDYKGIDVLPADIALSSAERE
                     FTQVGSEHRLKRVLQPIKDNYDYIIIDCPPSLGMLTVNAFTVSDEIIIPVEAAYFSLK
                     GLIKLSETIETVKEYTNDKLEVRGVLFTKYNKRYNISKEMTTAATEISRVIGAKIFKT
                     YIRRTITVDEAQAAGSDLINFNKPSTAEDDYKAFTEEYLKEVGDFDGRR"
BASE COUNT         1562 a          955 c          710 g         1954 t
ORIGIN      
        1 tcgtcgtgac tccttctaag cctttatctg taaaatttat tcctccagtt tttattcttc
       61 tttatccgct acaaattcaa tgatttcaaa gctgacaata taatcactca aatatgacca
      121 agtatcttca acagataatt cgtctccatt atcattcata agcgtcattt taaaccattc
      181 attaccttca tcatcttcag gtagcaagcc gaatccaatt ggattatcag tcaatgtttg
      241 atcgtataaa tcatcctcgt ctaatgctaa aacatctaat cctttacaat ttccgcctct
      301 tctaaacgtc acaaatcctt tgtaatccca acgttggaaa gaaaccttaa tcgtatgtgt
      361 gcccaatcgt atattcggat cataattttt catttgttgt aacctcctca taatcagtta
      421 gtactataaa ggtatctttg tttttatcca aaaaatctaa taaatctttt atagaagata
      481 tctcttcatc aacttcacca taataaatac cttcgataat tgttgctata tctgaaaaac
      541 taatttttac tggacattta tcgtctaccg cattcaatac cgacaaaatt gcttcttttt
      601 ctgcaatctc tcgtttgaat ttctttggag ctaatcgcat gacactcaag tcattttcaa
      661 gcttttcaat ccatgcagtt ttactcattt tcgcaaattt ttgaatcatt cctctaccac
      721 ctttgctatc tactaaatta gttttacttc ataacgaata tctttatcgt ttttcgttca
      781 ctcaaaaata tataaaataa atcgactcgt ttatggcgtc cgaaacgaga aaccctagta
      841 gacagcggta aatgctcgat tgatccaatg atcaacgtcc tcgcaagtat ctacatgtac
      901 tgcagcacac gacacaattt cttgtgcgtc ctccccatta cgagaagacc tactccttat
      961 tccatgagtt tgcgtcaaag cctagatccc ttagtagctg ctcatgatta atctaggcgc
     1021 tattctaact tgtctaactt ctaaattccc tcttgtttac tctgtgcata ttatttacac
     1081 aaattcattt caccactatc caaacaaggg catttactcg attgaccaat tttttacgtt
     1141 accaatcgta aaaacctacc ccgtcactcc ccgaagggaa ttgttgatag atcaagtcta
     1201 ctccttattt ttctagtgat tctaagttcc tttagaagtc tcgacaatat tttcaagcaa
     1261 gcgaaaaacg ataaaataca agttatgaga atgatcaatt cagctgatta aacgccccat
     1321 cccttttgcg gtacaacgca agactccatt ttttcttcga ccaatcagta caccgttttg
     1381 gtcataaaca tgtttgattg ttggatatag ctcttttaaa gggataggat cttttaaaat
     1441 tatttgtttt tgtttcccaa tgtaataaat catttcttct gagactttgt ctttctggat
     1501 tatatatttc ttacactgca caacggtttt actttgacca gttgatagtt tcttcgtgat
     1561 cttttctgta gcggtacacc gtttaccgta gtgacaaata tcttcgagac tcaaaattcc
     1621 tgtatatgac ataaaataat ccacccactt actttaaata tttttaacaa gtttttcttg
     1681 ttatttttca aaaatagaga attgattttc gttcatgaca aacaaaaaag agggaacgca
     1741 ttcaaacatg cgttccctct aatttcagcg ttcgtcatac ggcaaagagc cccacggaca
     1801 tttttataac attatgctta ggcatagatt catcgtaata tcacgtattt ttaaccttaa
     1861 cacagccaaa aaaagtggta tcacttttga atatctgtta tactaaatcc gttacgggta
     1921 ataccgtaac actgaaaggt aaacgcatta aggggtatag acttaatgcc acctgtggac
     1981 gtcgacgaag gttaccagcc ttccgagtct cacagggcct ttcttttttt tgtattttca
     2041 attgtccaaa tttatcgtcc aaaagtgcag aacgaaaatc aattcatcac aagcatagca
     2101 gacaattaaa tttaaaacaa ctaaaaatat acaaaaaagt gtaattgaat attagcagca
     2161 ctgcctgaaa agaagtaata tcaggctttt cagcttgggg aaataagtga attacctctc
     2221 ttcatgaatt attataactc aaaaaagcac atatgcaaac actagttccc tatttttttg
     2281 agtgaaaaat aactaaaata tctaacgatt atgaatttaa aacctacgat tgtgattgtt
     2341 ttcataaact tttaatctaa aaactccgga atactaacta tttatttgta atatttgtaa
     2401 taaaattaaa atcataaaaa agttctaatt taaaattgat catttttata gtaattgctt
     2461 tttatcaact actctaacca attttccgta ctaactgttg gtaattcgtt aaatgtttct
     2521 ctttgttcgt ttgcaagctt tgccgcaata gctttttcga caaaccaatt ttttacataa
     2581 acgaaaatta gattctgcaa attgtttact ttttcagttt tttgtttttg ataagctttc
     2641 agtaaagtca tatataatcc tttgtcagca tcaattccat aagattccag ttcttcataa
     2701 acgacaatag tttgctctaa ttcttcagct tttttctttg cattatgaat agtttggacg
     2761 gtttgttgag cttcactgta acttgaagaa aatgttttta tcaagtttaa tacattttct
     2821 ggtacaaatg tatttatact gtcctcttgc atgatgtcga cgaagttatc tagcaaaact
     2881 tgattttgta actggtcagt ttcagtgtct attatgtgtc tattagtgtc tatagaatta
     2941 gaatagaata gattgtctgc gattttcgca attacggttg agtccttgat atgactggat
     3001 tttgccgtat ttgcgatttt cgcaattacg gtagaatcat tgatttttcg cggttttgcc
     3061 gtatttgcga ttttcgcaat tacggtggaa tcagtattgt cttcctcttc catgatttta
     3121 aagacgtctt gattcgtaac ttctggcttg cctaagtaca ataaattagg catagattca
     3181 atcttaccat cacgtttatt tactcttcct ctcttctgtt tcagaagacc tgctttttct
     3241 aattcttttt tgatcttaga tactttacct tcgcggcatt gtaacaattt cattaattct
     3301 tcaactgtga atatgaagaa tatattatca tcagaatcta cccagttatt tttgactgaa
     3361 taatcaaatc gatctttaag tagcatataa gcaatttttg catcatttga aagatccatg
     3421 tatttttcgt tagtaaaaaa taccttaggc atttgataat atttttcacg ataaatttct
     3481 tttgatttgt aataattaaa atcattcata gccaatcctc tttctgtagg atagcgtttt
     3541 gttcaaaact atgttacaat gaattaaaca aatatatcta tccactatat atttttctac
     3601 tgctgataag tcgccaaact ttgttaaagc agtagtcttt ttttatcttt ttttagttta
     3661 ccttaaaaaa taaattaaag caaaccgctc tatttcaggg tttaagctca tggtaactat
     3721 atcacgatat tacaataaca ttatatcacg atatcgtaat attacaatat gaagataagc
     3781 gacttatcag ctttgatact actgattttt ataaaaaaaa tatcacgata ttatgatatc
     3841 gtgatattga atgtaaatta aattttattt tgtttctttg ctagtttata tccttcaatc
     3901 aagtattctt caggtatgga ttttaatagc gcatcttcta taacgtctgg tttacttttg
     3961 tctgattcag caatagtcgt ccaatatttg agtgctgaca ttagaattgg atttatacga
     4021 atgctatctg ctgttcttac actacttcct tgatctttta tgactttact tatatttttc
     4081 ttggttaatt cgatttcttc tacttctttt ggtttgtagt tctttttatt tttatttcct
     4141 agtagtctac ttactgcagc ttgactgcga ttatcttctg ccatcaaaat caccaacttc
     4201 ttttaaatat tcttctgtaa atgctttata gtcatcttca gctgttgagg gtttattaaa
     4261 attgattaga tctgatccag cagcttgcgc ttcgtcaacg gttattgttc tacgaatata
     4321 agttttgaaa atttttgcac caatgactct agaaatttcg gttgctgcag tcgtcatttc
     4381 tttagaaatg ttataacgct tattatactt agtaaatagg actcctcgta cttcaagctt
     4441 gtcgttcgta tattctttta ccgtttcaat agtttcactt aactttatta gtccttttaa
     4501 tgagaaatac gcagcttcaa ctggaatgat aatttcatca gaaacagtaa atgcgttgac
     4561 tgtaagcatt cctaaacttg gtggacaatc aattataata taatcatagt tgtccttgat
     4621 tggttgaagt actcttttaa gcctgtgttc acttcctact tgagtaaatt ccctctctgc
     4681 agaagaaagg gctatgtcgg ctggcaaaac atcaattcct ttatagtcca gaatagcatc
     4741 tgtaatgtca gcctcccctt ttaatacttc ataaattgta ggttggtttg ttccatctat
     4801 atcgaaacct acattatctg tagcatttcc ctgaggatca atgtccacta aaagtacatt
     4861 tttaccgtaa acaaatttca aacatgctgc taaattaacg ctagtcgtag ttttagaaac
     4921 tccacctttt tgattggcta ctgacaatat tcttgccatt aaaatatccc ccattcatct
     4981 tatattataa tataattata tcataatatt gtgatattgc aatatcgtat atgcattata
     5041 ttgtaatatt gtgtgattat tttgttttaa agatatatat cggttcggat ataaagatta
     5101 ttcatatgtt attcgaaagt aaaataatca ctttttatta ctttaaaatt ttttattaat
     5161 cataagaaat atgttttgcg a
//
LOCUS       DAPBAF010000095         4859 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.100, whole genome shotgun sequence.
ACCESSION   DAPBAF010000095 DAPBAF010000000
VERSION     DAPBAF010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4859)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4859)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4859
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.100"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            59..754
                     /gene="vanR"
                     /locus_tag="RD451_002783"
     CDS             59..754
                     /gene="vanR"
                     /locus_tag="RD451_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HDT7567966.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            732..1886
                     /locus_tag="RD451_002784"
     CDS             732..1886
                     /locus_tag="RD451_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HDT7567967.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
     gene            2101..3069
                     /locus_tag="RD451_002785"
     CDS             2101..3069
                     /locus_tag="RD451_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HDT7567968.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            3062..4093
                     /gene="vanA"
                     /locus_tag="RD451_002786"
     CDS             3062..4093
                     /gene="vanA"
                     /locus_tag="RD451_002786"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HDT7567969.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            4099..4707
                     /locus_tag="RD451_002787"
     CDS             4099..4707
                     /locus_tag="RD451_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HDT7567970.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
     gene            complement(4767..>4859)
                     /locus_tag="RD451_002788"
     CDS             complement(4767..>4859)
                     /locus_tag="RD451_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014125701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HDT7567971.1"
                     /translation="RGLYKKTRKEGTLFGFSVCTEIKVLLGIPA"
BASE COUNT         1494 a          934 c         1133 g         1298 t
ORIGIN      
        1 ttcggcccta taatctgata aattattaag ggcaaactta tgtgaaaggg tgataactat
       61 gagcgataaa atacttattg tggatgatga acatgaaatt gccgatttgg ttgaattata
      121 cttaaaaaac gagaattata cggttttcaa atactatacc gccaaagaag cattggaatg
      181 tatagacaag tctgagattg accttgccat attggacatc atgcttcccg gcacaagcgg
      241 ccttactatc tgtcaaaaaa taagggacaa gcacacctat ccgattatca tgctgaccgg
      301 gaaagataca gaggtagata aaattacagg gttaacaatc ggcgcggatg attatataac
      361 gaagcccttt cgcccactgg agttaattgc tcgggtaaag gcccagttgc gccgatacaa
      421 aaaattcagt ggagtaaagg agcagaacga aaatgttatc gtccactccg gccttgtcat
      481 taatgttaac acccatgagt gttatctgaa cgagaagcag ttatccctta ctcccaccga
      541 gttttcaata ctgcgaatcc tctgtgaaaa caaggggaat gtggttagct ccgagctgct
      601 atttcatgag atatggggcg acgaatattt cagcaagagc aacaacacca tcaccgtgca
      661 tatccggcat ttgcgcgaaa aaatgaacga caccattgat aatccgaaat atataaaaac
      721 ggtatggggg gttggttata aaattgaaaa ataaaaaaaa cgactattcc aaactagaac
      781 gaaaacttta catgtatatc gttgcaattg ttgtggtagc aattgtattc gtgttgtata
      841 ttcgttcaat gatccgaggg aaacttgggg attggatctt aagtattttg gaaaacaaat
      901 atgacttaaa tcacctggac gcgatgaaat tatatcaata ttccatacgg aacaatatag
      961 atatctttat ttatgtggcg attgtcatta gtattcttat tctatgtcgc gtcatgcttt
     1021 caaaattcgc aaaatacttt gacgagataa ataccggcat tgatgtactt attcagaacg
     1081 aagataaaca aattgagctt tctgcggaaa tggatgttat ggaacaaaag ctcaacacat
     1141 taaaacggac tctggaaaag cgagagcagg atgcaaagct ggccgaacaa agaaaaaatg
     1201 acgttgttat gtacttggcg cacgatatta aaacgcccct tacatccatt atcggttatt
     1261 tgagcctgct tgacgaggct ccagacatgc cggtagatca aaaggcaaag tatgtgcata
     1321 tcacgttgga caaagcgtat cgactcgaac agctaatcga cgagtttttt gagattacac
     1381 ggtataacct acaaacgata acgctaacaa aaacgcacat agacctatac tatatgctgg
     1441 tgcagatgac cgatgaattt tatcctcagc tttccgcaca tggaaaacag gcggttattc
     1501 acgcccccga ggatctgacc gtgtccggcg accctgataa actcgcgaga gtctttaaca
     1561 acattttgaa aaacgccgct gcatacagtg aggataacag catcattgac attaccgcgg
     1621 gcctctccgg ggatgtggtg tcaatcgaat tcaagaacac tggaagcatc ccaaaagata
     1681 agctagctgc catatttgaa aagttctata ggctggacaa tgctcgttct tccgatacgg
     1741 gtggcgcggg acttggattg gcgattgcaa aagaaattat tgttcagcat ggagggcaga
     1801 tttacgcgga aagcaatgat aactatacga cgtttagggt agagcttcca gcgatgccag
     1861 acttggttga taaaaggagg tcctaagaga tgtatataat tttttaggaa aatctcaagg
     1921 ttatctttac tttttcttag gaaattaaca atttaatatt aagaaacggc tcgttcttac
     1981 acggtagact taataccgta agaacgagcc gttttcgttc ttcagagaaa gatttgacaa
     2041 gattaccatt ggcatccccg ttttatttgg tgcctttcac agaaagggtt ggtcttaatt
     2101 atgaataaca tcggcattac tgtttatgga tgtgagcagg atgaggcaga tgcattccat
     2161 gctctttcgc ctcgctttgg cgttatggca acgataatta acgccaacgt gtcggaatcc
     2221 aacgccaaat ccgcgccttt caatcaatgt atcagtgtgg gacataaatc agagatttcc
     2281 gcctctattc ttcttgcgct gaagagagcc ggtgtgaaat atatttctac ccgaagcatc
     2341 ggctgcaatc atatagatac aactgctgct aagagaatgg gcatcactgt cgacaatgtg
     2401 gcgtactcgc cggatagcgt tgccgattat actatgatgc taattcttat ggcagtacgc
     2461 aacgtaaaat cgattgtgcg ctctgtggaa aaacatgatt tcaggttgga cagcgaccgt
     2521 ggcaaggtac tcagcgacat gacagttggt gtggtgggaa cgggccagat aggcaaagcg
     2581 gttattgagc ggctgcgagg atttggatgt aaagtgttgg cttatagtcg cagccgaagt
     2641 atagaggtaa actatgtacc gtttgatgag ttgctgcaaa atagcgatat cgttacgctt
     2701 catgtgccgc tcaatacgga tacgcactat attatcagcc acgaacaaat acagagaatg
     2761 aagcaaggag catttcttat caatactggg cgcggtccac ttgtagatac ctatgagttg
     2821 gttaaagcat tagaaaacgg gaaactgggc ggtgccgcat tggatgtatt ggaaggagag
     2881 gaagagtttt tctactctga ttgcacccaa aaaccaattg ataatcaatt tttacttaaa
     2941 cttcaaagaa tgcctaacgt gataatcaca ccgcatacgg cctattatac cgagcaagcg
     3001 ttgcgtgata ccgttgaaaa aaccattaaa aactgtttgg attttgaaag gagacaggag
     3061 catgaataga ataaaagttg caatactgtt tgggggttgc tcagaggagc atgacgtatc
     3121 ggtaaaatct gcaatagaga tagccgctaa cattaataaa gaaaaatacg agccgttata
     3181 cattggaatt acgaaatctg gtgtatggaa aatgtgcgaa aaaccttgcg cggaatggga
     3241 aaacgacaat tgctattcag ctgtactctc gccggataaa aaaatgcacg gattacttgt
     3301 taaaaagaac catgaatatg aaatcaacca tgttgatgta gcattttcag ctttgcatgg
     3361 caagtcaggt gaagatggat ccatacaagg tctgtttgaa ttgtccggta tcccttttgt
     3421 aggctgcgat attcaaagct cagcaatttg tatggacaaa tcgttgacat acatcgttgc
     3481 gaaaaatgct gggatagcta ctcccgcctt ttgggttatt aataaagatg ataggccggt
     3541 ggcagctacg tttacctatc ctgtttttgt taagccggcg cgttcaggct catccttcgg
     3601 tgtgaaaaaa gtcaatagcg cggacgaatt ggactacgca attgaatcgg caagacaata
     3661 tgacagcaaa atcttaattg agcaggctgt ttcgggctgt gaggtcggtt gtgcggtatt
     3721 gggaaacagt gccgcgttag ttgttggcga ggtggaccaa atcaggctgc agtacggaat
     3781 ctttcgtatt catcaggaag tcgagccgga aaaaggctct gaaaacgcag ttataaccgt
     3841 tcccgcagac ctttcagcag aggagcgagg acggatacag gaaacggcaa aaaaaatata
     3901 taaagcgctc ggctgtagag gtctagcccg tgtggatatg tttttacaag ataacggccg
     3961 cattgtactg aacgaagtca atactctgcc cggtttcacg tcatacagtc gttatccccg
     4021 tatgatggcc gctgcaggta ttgcacttcc cgaactgatt gaccgcttga tcgtattagc
     4081 gttaaagggg tgataagcat ggaaatagga tttacttttt tagatgaaat agtacacggt
     4141 gttcgttggg acgctaaata tgccacttgg gataatttca ccggaaaacc ggttgacggt
     4201 tatgaagtaa atcgcattgt agggacatac gagttggctg aatcgctttt gaaggcaaaa
     4261 gaactggctg ctacccaagg gtacggattg cttctatggg acggttaccg tcctaagcgt
     4321 gctgtaaact gttttatgca atgggctgca cagccggaaa ataacctgac aaaggaaagt
     4381 tattatccca atattgaccg aactgagatg atttcaaaag gatacgtggc ttcaaaatca
     4441 agccatagcc gcggcagtgc cattgatctt acgctttatc gattagacac gggtgagctt
     4501 gtaccaatgg ggagccgatt tgattttatg gatgaacgct ctcatcatgc ggcaaatgga
     4561 atatcatgca atgaagcgca aaatcgcaga cgtttgcgct ccatcatgga aaacagtggg
     4621 tttgaagcat atagcctcga atggtggcac tatgtattaa gagacgaacc ataccccaat
     4681 agctattttg atttccccgt taaataaact ttggttctgt tgcaaagttt taaataaaga
     4741 ataaaatccc ttacggtatc tatgatttaa gctgggattc ccaataatac cttgatttca
     4801 gtacagaccg aaaacccgaa gagagtgcct tcttttcggg ttttcttata taatcctcg
//
LOCUS       DAPBAF010000096         4809 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.101, whole genome shotgun sequence.
ACCESSION   DAPBAF010000096 DAPBAF010000000
VERSION     DAPBAF010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4809)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4809)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4809
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.101"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(91..1176)
                     /gene="xerS"
                     /locus_tag="RD451_002789"
     CDS             complement(91..1176)
                     /gene="xerS"
                     /locus_tag="RD451_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HDT7567972.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLENNPMDQVATITDKTTLAARAN
                     AIEKKLFLDEDTQNYLDYIANEYKKTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VVNINLEDLSLEKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRVQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHTSTNTTTLYTHIDNAATIDALNAL"
     gene            complement(3252..3770)
                     /locus_tag="RD451_002790"
     CDS             complement(3252..3770)
                     /locus_tag="RD451_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HDT7567973.1"
                     /translation="MRTYKNKEELKKEINRTYTKYILEFETIPEELKDKRVEEVDRTP
                     AENLAYQVGWTNLILKWENDERNGLSVKTPSDQFKWNQLGELYKWFTNTYAHLPLKEL
                     EEILNRNIDDINMMIDSMSDEDLFTAHKRKWADEATKTAVWEVYKFIHVNTVAPFGTF
                     RTKIRKWKRLAL"
BASE COUNT         1580 a          786 c          729 g         1714 t
ORIGIN      
        1 tataaaaatg ataatgaagc ttgcctttaa agttgggctt ttatctaatt ttagagacag
       61 gcttcattat tatactattt tttactacat ttacaaagcg ttcaaagcat caattgtagc
      121 tgcattgtct atatgagtat ataaagttgt tgtatttgta cttgtatgtc ccaattgttg
      181 ggcagttaat accaatgaat ttgtctgttg atagagtcta gtagccaaag tatgacgtaa
      241 tttatgtgga ctgacttgga ctctgaatcc ttttgaatat tttgctacca tccgttcgat
      301 tgcaataccg gatatacgct tggcttctcc ttgataaatt gctagaaata aagctttttc
      361 gttttctgtt actttgtatc gttctttccg aatagctaga taattagcta aatattccat
      421 tgcaaatgct gctatattta ctgcgtctct cttatttcct tttctagtta ctaccacatt
      481 attcttttct aaagataggt cctctaaatt aatatttaca acctcggaga gtcttaatcc
      541 agatcctaaa atcaatgcat tgatcgccag gtctctttct acatctcgtt gataatagat
      601 caaagctcgt ttgctcaaag tttttttata ttcattggca atataatcta gataattttg
      661 tgtatcttcg tctagaaata attttttctc gattgcgttt gcacgggcag ctaacgtagt
      721 tttatctgtg atagttgcta cttgatccat aggattattt tctaagtatg gttttcctaa
      781 aggattattg gaacttttcg aaagatattt aaatagaacc tttaatgctg tgatatttct
      841 attgatagta gaagtagata gacctaagtt attattatct ttgagcttag tttttgttgt
      901 ctcttttttt acattttcct ttgtgcgacg tttcaaatga gatttgtaca agtttagatc
      961 ataggcagtt aactgtctta tcgaggtgat tgaagtatcg ggaacgatag actcactcag
     1021 aagccattca taaaagagct tataattttt tagatattct aaagtagttc gaggtgattg
     1081 atctttatcc tcacgatctt gaacaaaatc ttttatataa tcgggcatat gaagtatgat
     1141 tgtatctatt ttttgatata tttctgtatt tttcatgtta ttcatccttt cgataagtag
     1201 gggagaggag tatctctata attggactat accaattata gagtgttttg tcaattggta
     1261 tactctgaaa tttattaatt tatttcaaaa aagcagataa ataggtatag atttaataat
     1321 ttaaaataaa tggtatacat gaataggaaa ggaaacagaa ggaggcaatc ttaatttttt
     1381 aaattgtcta aattatatag aaagaacaat ctttctatat aattagacat aagagagact
     1441 acggttgatt tgatattaac aagcgtatat gaatgtatat acaaataaaa aaggggaggg
     1501 agaagttaaa gaaaattcag agaagtgggg cactcagtag tattaacaat ttaaaaggaa
     1561 tttcttaaag aaaatgggtt gcatcctgga gatacaattt ttttagataa agaaaaaatt
     1621 caagcaacaa ttcaaaaaaa tcttaactgc tgagattgat gtagcaatat ctcaatcatc
     1681 aacaaagtac gatcctgcct ttcaaaagct tattgataaa tgtttattca ttataaaaat
     1741 aaaagaaaaa tttatgtcag cttttttcat caaagtggta atgataattc gtctattaat
     1801 tgtatttttt aggaaatatg gtataattgt tttaacgaaa aggtaattca tgatacacca
     1861 aaaaccacta gctggcgggc tagtggtttt cttttacgtt ctattcagat taacgggtag
     1921 gcttactgtc ttttttggca ataattttgc aatcaagcca tttacagatg taatgcgcgg
     1981 atacttctgc taagattgca aaaaacatat cgaaaaggta attcataata caacctcctc
     2041 cccttgccat aataggccgg ggtagcagac agcataaata ttataccata actgaaaatt
     2101 tcattttagt acatttcaat atattgatga accagcacaa taaaacatgc catgactaac
     2161 agaaaaaaac ttattaaacc agatataact tgtaaacatc caactatata gaaaacgtaa
     2221 attttctata tagttggatt aagataacga ctatttattt tatcatattt ttactatacc
     2281 ctatactttt acttggtata tttatgaata atcgcaaatt tacccctata ctactagttt
     2341 gtaagttaga ttaataaaaa tactaaagtt atttgttctt ttattaaata cacctacaac
     2401 ttataaattg atggtattta gataacacga aagaataaaa ataacagctg atagtaaagt
     2461 ttgttgacga ttgctactca atcgaaagtg agttagtgcg tatgaacttg cttctgaaaa
     2521 cttatgaaat gaaagacctt ttacatcttg cagaaatcgt tactgggatt aaactaagca
     2581 ataaaaacta atgttcccct cattctttga acttctacta tttgatttat ttattctgat
     2641 aaatgacgat ttcaccttca ggatcttcaa atcccgtata gaatttattt aagatctctt
     2701 cagtatcagt aataggatag gcgataggcc acataccctt tgatggttag aataaactgc
     2761 tcaaaatctg tatcgtatgt tggctttagc atattaacaa aggctatctc caaattataa
     2821 accataagcg ttgaatcgtt cttaacaatt tcaattcttc ctaacccaaa gtcagaagat
     2881 ataattaccg gacttgcctt acccttcatg tgggttgttg agattccata tttaaaggga
     2941 attgtcggta ctatcggcgg tctgaaaaac atcccaaaaa taaaaaaatc tttcccctgc
     3001 tagtctccta agtccctttg tagcggatat ggcaccataa tctcatttta tcgaagtgag
     3061 tcatggttta tctgttggcc aaccaaaatt gatacaatct aacgatgcac cctctacggc
     3121 attctagggg agtgcacttg cattcaccca ataaaaaccg gcagttagca aagaacttat
     3181 gtagtcgtat gttcttactg ttaacataca agaggtctcc tttccacaat tgcttagcag
     3241 taaacgggaa tttacaaagc taatctcttc cattttctta tctttgttct aaaagtccca
     3301 aatggagcaa ctgtatttac atgaataaat ttatatactt cccatacagc cgttttggtt
     3361 gcctcgtctg cccattttct tttgtgtgca gtgaatagat cttcatcact cattgaatca
     3421 atcatcatgt taatatcatc aatattacga ttgagaattt cctctaattc tttcaatggt
     3481 agatgtgcat aggtatttgt aaaccactta tataactctc ctaactgatt ccatttaaat
     3541 tgatcagaag gcgttttaac agataatcca tttctttcat cattttccca ttttagaatt
     3601 aaattcgtcc aaccaacttg atatgctaaa ttttcagcag gtgttctatc cacttcctca
     3661 actcttttat ccttcaattc ttcaggaata gtttcaaatt ctaaaatata tttagtataa
     3721 gtcctattta tttctttttt taattcttct ttatttttat atgttctcat tatattacct
     3781 ccataaattc ctaattgtct cctttaattc atctataatt tcatccacga tattttaatc
     3841 cgttctacaa tgcatatctg atatgcattg actgtctaac tcatatgtga atgatttata
     3901 aaatatccca acgtctcatc taaagaaatg ttgatcgtca gcaaggagct aaaaaatacg
     3961 aatatatttc ttttgtagta aaatcggact ggtttgcata tcattttctt cgtaaatatc
     4021 aaaatcatgt taactactat caattactaa taaaaactac cactttaagc gttaagaact
     4081 gttaagttta gttaagtgag gatagttcac aaaatccatt gttaaacttc acgaaagtgg
     4141 taaaactcaa aatgctttat ataggattac agcatcgctc tttcttcgat tgcgcgttgg
     4201 gtaaaaaata ttatgaagta aaaattgacg atgacacgtt ccttacggct catcagatga
     4261 aacagctaca aaaacgaaat gatcaactcg aagaaaattt aattctaaaa aagcgattgc
     4321 catattcacg cctcgctcga cgaactatta aaggtcaaga tttacctgaa gatcatcctt
     4381 tttaggaaat tgaagctttt tatgttgcac aatgcattta taatactaca atgatgtttt
     4441 caccagatat tcttctaggg tgcggtgtaa tgaaacagat acacttgcaa aagaaaattc
     4501 accgcgaatt tactaaaatt atgaataatt atgttaatct tccgaaattt ttttccaaaa
     4561 ttaagggatc aagctggtgt tatagattgt ttaaggttgg caaaaaaata acttcttttt
     4621 aaacaattat agaaaaccga tactctgtta agttggttga cacggtgtcg atttttatga
     4681 ctttcttatt ctgaaacttc actaacggac agtacctaaa aagtctatag tatggacgtt
     4741 tacgagtact attttatcaa aaatgctgct catttcaact tatatgtttt agtgaactac
     4801 ccccactta
//
LOCUS       DAPBAF010000097         4595 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.103, whole genome shotgun sequence.
ACCESSION   DAPBAF010000097 DAPBAF010000000
VERSION     DAPBAF010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4595)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4595)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4595
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.103"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            106..357
                     /locus_tag="RD451_002791"
                     /pseudo
     CDS             106..357
                     /locus_tag="RD451_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            450..1244
                     /locus_tag="RD451_002792"
                     /note="aph(3')-IIIa"
     CDS             450..1244
                     /locus_tag="RD451_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HDT7567974.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
     gene            1654..1737
                     /locus_tag="RD451_002793"
                     /pseudo
     CDS             1654..1737
                     /locus_tag="RD451_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527320.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
     gene            1786..1869
                     /locus_tag="RD451_002794"
     CDS             1786..1869
                     /locus_tag="RD451_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuator leader
                     peptide ErmL"
                     /protein_id="HDT7567975.1"
                     /translation="MLVFQMRYVDKTSTVLKQTKNSDYADK"
     gene            1994..2731
                     /gene="erm(B)"
                     /locus_tag="RD451_002795"
     CDS             1994..2731
                     /gene="erm(B)"
                     /locus_tag="RD451_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HDT7567976.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESRASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            complement(2994..3857)
                     /locus_tag="RD451_002796"
     CDS             complement(2994..3857)
                     /locus_tag="RD451_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin zeta"
                     /protein_id="HDT7567977.1"
                     /translation="MANIVNFTDKQFENRLNDNLEELIQGKKAVESPTAFLLGGQPGS
                     GKTSLRSAIFEETQGNVIVIDNDTFKQQHPNFDELVKLYEKDVVKHVTPYSNRMTEAI
                     ISRLSDQGYNLVIEGTGRTTDVPIQTATMLQAKGYETKMYVMAVPKINSYLGTIERYE
                     TMYADDPMTARATPKQAHDIVVKNLPTNLETLHKTGLFSDIRLYNREGVKLYSSLETP
                     SISPKETLEKELNRKVSGKEIQPTLERIEQKMVLNKHQETPEFKAIQQKLESLQPPTP
                     PIPKTPKLPGI"
     gene            complement(3859..4131)
                     /locus_tag="RD451_002797"
     CDS             complement(3859..4131)
                     /locus_tag="RD451_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HDT7567978.1"
                     /translation="MAVTYEKTFEIEIINELSASVYNRVLNYVLNHELNKNDSQLLEV
                     NLLNQLKLAKRVNLFDYSLEELQAVHEYWRSMNRYSKQVLNKEKVA"
     gene            complement(4148..4357)
                     /locus_tag="RD451_002798"
     CDS             complement(4148..4357)
                     /locus_tag="RD451_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HDT7567979.1"
                     /translation="MGNLGAQKAKRNDTPISAKKDIMGDKTVRVRADLHHIIKIETAK
                     NGGNVKEVMDQALEEYIRKYLPDKL"
     gene            complement(4455..>4595)
                     /locus_tag="RD451_002799"
     CDS             complement(4455..>4595)
                     /locus_tag="RD451_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParA"
                     /protein_id="HDT7567980.1"
                     /translation="RSNKVSTWSKNGITEHKGYDKKVLSMYKNVFFEMLERIIQLENE
                     KE"
BASE COUNT         1412 a          775 c          847 g         1561 t
ORIGIN      
        1 ttcttgggag ttttgagact actatatgcg tttttttgtt gatttaccaa catgtttaga
       61 cattttcctc taggaaaaaa ttaactagca ccacgggtta tcttttatat agaagatatc
      121 gccgtatgta aggatttcag ggggcaaggc ataggcagcg cgcttatcaa tatatctata
      181 gaatgggcaa agcataaaaa cttgcatgga ctaatgcttg aaacccagga caataacctt
      241 atagcttgta aattctatca taattgtggt ttcaaaatcg gctccgtcga tactatgtta
      301 tacgccaact ttgaaaacaa ctttgaaaaa gctgttttct ggtatttaag gttttagaat
      361 gcaaggaaca gtgaattgga gttcgtcttg ttataattag cttcttgggg tatctttaaa
      421 tactgtagaa aagaggaagg aaataataaa tggctaaaat gagaatatca ccggaattga
      481 aaaaactgat cgaaaaatac cgctgcgtaa aagatacgga aggaatgtct cctgctaagg
      541 tatataagct ggtgggagaa aatgaaaacc tatatttaaa aatgacggac agccggtata
      601 aagggaccac ctatgatgtg gaacgggaaa aggacatgat gctatggctg gaaggaaagc
      661 tgcctgttcc aaaggtcctg cactttgaac ggcatgatgg ctggagcaat ctgctcatga
      721 gtgaggccga tggcgtcctt tgctcggaag agtatgaaga tgaacaaagc cctgaaaaga
      781 ttatcgagct gtatgcggag tgcatcaggc tctttcactc catcgacata tcggattgtc
      841 cctatacgaa tagcttagac agccgcttag ccgaattgga ttacttactg aataacgatc
      901 tggccgatgt ggattgcgaa aactgggaag aagacactcc atttaaagat ccgcgcgagc
      961 tgtatgattt tttaaagacg gaaaagcccg aagaggaact tgtcttttcc cacggcgacc
     1021 tgggagacag caacatcttt gtgaaagatg gcaaagtaag tggctttatt gatcttggga
     1081 gaagcggcag ggcggacaag tggtatgaca ttgccttctg cgtccggtcg atcagggagg
     1141 atatcgggga agaacagtat gtcgagctat tttttgactt actggggatc aagcctgatt
     1201 gggagaaaat aaaatattat attttactgg atgaattgtt ttagtaccta gatttagatg
     1261 tctaaaaagc tttaactaca agctttttag acatctaatc ttttctgaag tacatccgca
     1321 actgtccata ctctgatgtt ttatatcttt tctaaaagtt cgctagatag gggtcccgag
     1381 cgcctacgag gaatttgtat cgataagaaa tagatttaaa aatttcgctg ttattttgta
     1441 catttaactt gacggtgaca tctctctatt gtgagttatt agtggtacag ttttcaaccg
     1501 ttttaattat aaaaaagtgg tgcattttta aattggcaca aacaggtaac ggttattgca
     1561 ggtgtatttc ttatctatgg gtttaacatg gattttatca ttaaaatcat gagtattgtc
     1621 cgagagtgat tggtcttgcg tatggttaac cctaaagtta tggaaataag acttagaagc
     1681 aaacttaaga gtgtgttgat agtgcattat cttaaaattt tgtataatag gaattgaagt
     1741 taaattagat gctaaaaatt tgtaattaag aaggagggat tcgtcatgtt ggtattccaa
     1801 atgcgttatg tagataaaac atctactgtt ttgaaacaga ctaaaaacag tgattacgca
     1861 gataaataaa tacgttagat taattcctac cagtgactaa tcttatgact ttttaaacag
     1921 ataactaaaa ttacaaacaa atcgtttaac ttctgtattt gtttatagat gtaatcactt
     1981 caggagtgat aacatgaaca aaaatataaa atattctcaa aactttttaa cgagtgaaaa
     2041 agtactcaac caaataataa aacaattgaa tttaaaagaa accgataccg tttacgaaat
     2101 tggaacaggt aaagggcatt taacgacgaa actggctaaa ataagtaaac aggtaacgtc
     2161 tattgaatta gacagtcatc tattcaactt atcgtcagaa aaattaaaac tgaatactcg
     2221 tgtcacttta attcaccaag atattctaca gtttcaattc cctaacaaac agaggtataa
     2281 aattgttggg aatattcctt accatttaag cacacaaatt attaaaaaag tggtttttga
     2341 aagccgtgcg tctgacatct atctgattgt tgaagaagga ttctacaagc gtaccttgga
     2401 tattcaccga acactagggt tgctcttgca cactcaagtc tcgattcagc aattgcttaa
     2461 gctgccagcg gaatgctttc atcctaaacc aaaagtaaac agtgtcttaa taaaacttac
     2521 ccgccatacc acagatgttc cagataaata ttggaagcta tatacgtact ttgtttcaaa
     2581 atgggtcaat cgagaatatc gtcaactgtt tactaaaaat cagtttcatc aagcaatgaa
     2641 acacgccaaa gtaaacaatt taagtaccgt tacttatgag caagtattgt ctatttttaa
     2701 tagttatcta ttatttaacg ggaggaaata attctatgag tcgcttttgt aaatttggaa
     2761 agttacacgt tactaaaggg aatgtagata aattattagg tatagggcac ctctaataac
     2821 taccaattaa ttcacctcaa aatgaaatta gaaaaaaaca gcgaaatttt taaatctatt
     2881 tcttatcgat acaaattcct cgtaggcgct cgggacccca acatgaggaa atgtttttat
     2941 aaaaaaagag tagttaccgt tttttggtaa ctactctttt ccttttttaa ggtttaaata
     3001 cctggaagtt taggtgtttt gggtattggt ggtgtaggtg gctgcaagct ttccaatttt
     3061 tgttgaattg ctttaaattc aggtgtctct tggtgtttat ttagaaccat tttttgctct
     3121 attcgttcta aagtcggttg aatttctttc cctgatactt tacgattcaa ttctttttct
     3181 aaggtttctt ttggactaat agaaggtgtt tccaaacttg aatagagttt tactccttct
     3241 ctgttatata gccttatatc gctaaataag cccgttttat gaagggtttc taaattggtc
     3301 ggtaagtttt tgacaacaat atcatgcgct tgttttggtg ttgccctggc tgtcattgga
     3361 tcatctgcat acatggtttc atatcgttca attgttccta aatatgagtt gattttaggt
     3421 actgccatga catacatttt tgtttcataa cctttggctt gaagcattgt tgcggtttga
     3481 ataggaacgt ctgttgttcg tcctgtacct tcgatcacca aattataccc ttgatcgctc
     3541 aaacggctta tgatcgcttc tgtcatgcga ttagaataag gggtaacgtg ttttactacg
     3601 tctttttcat aaagtttcac tagttcatca aaattagggt gctgttgttt aaaggtatca
     3661 ttatcaatga caataacatt cccttgtgtt tcttcaaaaa ttgctgatcg caaactggtt
     3721 ttccctgacc ctggttgccc accaagtaaa aaagcggttg gcgattcaac cgcttttttt
     3781 ccttgaatca attcttctaa attatcattt aagcgattct caaattgttt gtcagtaaaa
     3841 ttgactatat ttgccatatt aagccacttt ctctttattc aaaacttgtt ttgagtaacg
     3901 attcattgac cgccaatact catgaacggc ttgtaattct tctaaagaat aatcaaaaag
     3961 atttacacgt tttgcaagct ttaattggtt taataaattg acttccaata attgagagtc
     4021 atttttattt aattcatggt tcaaaacata gtttaatact cgattataaa cgcttgccga
     4081 taattcgtta atgatctcta tttcaaatgt tttttcatac gtaactgcca tttcattttc
     4141 actcctttta aagtttgtca ggtaaatatt tccgtatata ttcttctaag gcttgatcca
     4201 taacttcttt tacgtttccg ccattctttg ctgtttcgat ttttatgata tggtgcaagt
     4261 cagcacgaac acgaaccgtc ttatctccca ttatatcttt ttttgcactg attggtgtat
     4321 catttcgttt tgctttttgt gcgcctaaat ttcccacaat cactcacttc tttctatttc
     4381 ttcttactct tattttatca tcaacaatca caaatcacaa gtgatttgtg attaatcact
     4441 tgtgatttgt gattctattc tttttcgttt tctaattgaa taattcgctc aagcatttca
     4501 aaaaatacgt tcttatacat ggataaaact tttttgtcat agcctttatg ctctgtaatg
     4561 ccgtttttag accaggtact tactttatta cttcg
//
LOCUS       DAPBAF010000098         4434 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.104, whole genome shotgun sequence.
ACCESSION   DAPBAF010000098 DAPBAF010000000
VERSION     DAPBAF010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4434)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4434)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4434
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.104"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(543..2048)
                     /locus_tag="RD451_002800"
     CDS             complement(543..2048)
                     /locus_tag="RD451_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDT7567981.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            complement(2045..2731)
                     /locus_tag="RD451_002801"
     CDS             complement(2045..2731)
                     /locus_tag="RD451_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7567982.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="RD451_002802"
     CDS             complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="RD451_002802"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HDT7567983.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
BASE COUNT         1239 a          919 c          729 g         1547 t
ORIGIN      
        1 tctttttgtt ttaacaactc tttaatctta tcagattcag aagagaatgt caacaacttc
       61 tttgtttatt ttttctaaac gtctttgcca ctcattagca gcgacttgat tatcatacca
      121 tctttattgt tatttgtcaa taactttttc gaagtttttt tcgataaaat caagctttat
      181 tagctatctc atccaaacga cttcgttatt ataacatgac atcaaaagtg cgtcaacact
      241 attttttata atttttagtg acaccttaaa ggaatcattt agaacaaata ataatatagc
      301 aatctcttta taaaattgca atagaaaatt ccctattttt atttattatt tttaaacacg
      361 aatattacag cattttattg ttttttcgtt catctaaaag atacttacat ttaattaacg
      421 gatgttattc tatttaattg ttcgctagtt tttttataat gacatccctg aatttctcac
      481 ttgcttgtat tttgtacctt attctttgtt ggatatataa aaaaacaagt aaagcacatg
      541 ctttacttgt cttctgcctt tgcgatagga ataaagattc taaaaattgt cccttgccct
      601 actacacttt ctgctaagat acgtccttta tagttttcaa ccagttgttt agcgatagac
      661 aaccccagac catttccacc cttcgttcta gctcttgctt tatccactcg ataaaaacga
      721 ttgaagatct tattaaggtc ttctttgggt attccttcgc caaagtcctg aatcgcgatc
      781 tcaaattcat tcagagtgga agaaatagag atatggactt cttttcgtgt agttgaatac
      841 tttactgcgt tatccaatat gataatgatt aattgttcaa agtgattacg ataaatttgc
      901 agggtcactt cttttgtcaa atcatcatct aaagtgatca catagtctgg atataatatc
      961 ttgaaattat tataaacttg ataggtgact tcttttcctt tagttgtttc attcgcataa
     1021 tgaacatcta cttgttctgc tcttgataag tctagcatct cttgaactaa gcttttcata
     1081 cggctgattt cttgcatgct ggcgcttaat gattcttcta atatctcagg atcatctttc
     1141 ccccaacgat ttagcagact aagatgccct tcaataattg caacaggtgt ccttaactca
     1201 tgagatacgt cttccacgaa ttgctcttgt tgttcaatat acaaacgcat acggtcaagc
     1261 atctcattga atatttcagc taaatctgcc aattcatcat ttgtgtcgat ttcaggcatg
     1321 tggatatctg attgcggatc tttacgtata gtatccattg tatctctgag taccttgagt
     1381 ggttttaaga aataagaaga taaaaagaaa cctaaaatac tacttaagat caaagaaaca
     1441 acttctaaaa caataagagt caataatagc ttatttcgaa tatcatagaa agaagataat
     1501 tcatagaagc tttgcgcata gccgatcttt tctcttgtac ctttagaata tataggctgg
     1561 atagataaaa agccagtttt tccttctagt gtaacgatcg ttggaacttt acgtgtagtc
     1621 tgaatcaggt ttcgactgtt ttcatgggtt ttaaaaatca agttctcgtc caaatcataa
     1681 acataaagat ccattgatgg ctgccctagc tcagctataa aggaatcgat cttcattaag
     1741 tttccttcga ccagtgaagt atgatctacg acctcatctc cgtcatttgt cgctttcgtc
     1801 agattacgat acgtatttac taatgtcagt tcttcatccg agttagccaa acgagaagct
     1861 acttctgaaa tcgtacgctc tacattgttt ctttcttttg ccacaatcag attgatagat
     1921 gatttatagg taatgacagc gaaaattgta aacacaacga atatgaagaa agaactcgca
     1981 aaggcccact tgattgtcaa ggagggccct ttcagttctc ttttttccga ttttttcggc
     2041 tttatcacga gcgcatcaca taacctgttc cgcgtacagt ttggatatag ctttcctccc
     2101 cgggaacgtc aattttgttg cgaagataac gaatatatac gtccactacg tttgtttcaa
     2161 cttctgtttc gtatccccac actttattta gtaaaacgtc acgtgctaat accacgttca
     2221 cgttttccat taaagtaagc agcaactcgt attctctttt tgttagttca attacttcat
     2281 ttccgcgacg tacgacacgg ttttcttttt cgatagtcaa atcgcgataa gtaatagtag
     2341 tttgtttagc cacattttta tcgccttcaa tatcgattcg acgcaacaat gcacgaagac
     2401 gtgctaataa ttcttcgata gcaaatggtt tgacgatgta gtcatctgct ccgtggtcaa
     2461 gtccagatac acgatcgatc acagaatctc ttgcagtcat cataatgatt ggtgtatttt
     2521 tgacttggcg tacacgtctg cagacttcta aaccgttcaa ttctgggagc atcagatcca
     2581 acaatatggc atcccactca ttatttaatg ccgcatctaa accagttcgg ccgttgtagt
     2641 ggacttctgc gttataccct tcatgcttca actctagctc gacaaatcgt gccaagttct
     2701 tttcatcttc aatgattaga atattgctca tttattattt tatcctttct attctactgg
     2761 ctttttaaaa actctatcat tataccgata atatgcttaa aaatctatag tcattttatc
     2821 atggatagca attttaaaaa agagctgaag tctactcata acaatcgact tcagctcttt
     2881 cgtcctcttt ttattttctc atttcctaac agccgaaaga ctattattct tcatggtacc
     2941 atgagtaatg gaagattcct tctttgtcga cacgctcata ggtatgtgcg ccaaagtaat
     3001 cgcgttgggc ttggattata tttgcaggca gacgttctgc tctgtatgaa tcgaagtaag
     3061 cgatggctga tgagaaagtc ggtacaggta cgccagcttg gacagccaag gcaacgacgt
     3121 ctctgactga ttgctgatat tttttcgtga tttcaacgaa gtaatcatct agcaataaat
     3181 tttcgatctc aggatttttg tcataggcat ccgtaatttt ttgcaagaat cgagctcgga
     3241 tgatacatcc agcgcgccag atttttgcga tttcaccaaa tggcaagtcc caatcaaatt
     3301 cttttgaagc gacacgtaat tgagcaaatc cttgggcata actcatgatt ttactgaaat
     3361 acaacgcttc tcggattttt tcgaccaatt cttttttgtc tcccgtgaac tcaaaatcgt
     3421 tcgtacgaga caaaatcttg cttgcttgta cgcgttcttc tttataagca gaaatatagc
     3481 gggcaaatac agattcagtg atcaatggaa gtggcacacc taagtcaagc gcgctttggc
     3541 ttgtccattt acctgttcct ttattcccag ctgcatcaag gatcacatct actactggtt
     3601 tacctgttcc ttcatcgtct ttacgtgtca gaatgtcagc agtgatttct atcaaatagc
     3661 tgtctaattc gccttgattc cattctttaa agatatcagc catttcttct actgaaaggt
     3721 ttaaaatatt cttcattaag tcataagatt cagcaatcag ttgcatatct ccatactcaa
     3781 taccgttgtg taccattttc acataatgtc cggctccatt tgggccaata tatgtgacac
     3841 atggtgctcc gtcttctgct tttgcagaaa tttgctctaa gattggtgca actagcgcat
     3901 aggcttcttt ttgtccacca ggcatgattg aaggtccttt taaagctcct tcttcaccac
     3961 cggaaacgcc tgtaccgata aagttgatgc cagagttggc taactcttca ttacgacgca
     4021 tcgtatcttt aaagaatgta tttcctccgt caatcaaaat atcgccttta tcaaggtgag
     4081 gaagtaactc ttggattgtt gcatctgttg ccggtcctgc tttgaccatt agcaagatcc
     4141 gacgtggttt ctcgatagat tctacaaatt cttcgattgt atatgttgct ttgaaatttt
     4201 tatctgggtg ttcttctact acagcggttg ttttagcccc tgtacgattg aataaagcca
     4261 ctgaatagcc gcggctttct atgttcaagg ctagattttt acccataacg gccataccga
     4321 caacgccgat ttgttgtttt gacatatgaa ctcctcctac atacgggatt tctccctaat
     4381 ctcttacatt atagcttaac acggctacat tgcaaactaa agaacaacat attt
//
LOCUS       DAPBAF010000099         4416 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.105, whole genome shotgun sequence.
ACCESSION   DAPBAF010000099 DAPBAF010000000
VERSION     DAPBAF010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4416)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4416)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4416
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.105"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            59..913
                     /locus_tag="RD451_002803"
     CDS             59..913
                     /locus_tag="RD451_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDT7567984.1"
                     /translation="MENSIYLVTEPNTQLKDCYFNFCGYSKTEPRHSFGPAIREQYLI
                     HIVLEGEGYYSINDQKYFLKKGQGFVIPPGVSTFYQADEKNPWSYVWLGLSGNLVEYY
                     LKEIGVGKNHLTFKVENLNSFKGLIFETLSYDQDNLVSELSRQKQVYKFLELLLNSAS
                     YLNEGIITKKMNPFVRQTIEIIRENAYQKLSVKDIAVSLSIHENYLSRLFKNDMGISI
                     KEYISEIKISIANDLLSSTEYSIQQISDKIGFSTVQSFSKAFKKANGVSPGVYRKRRL
                     GLGIINGE"
     gene            1010..3259
                     /locus_tag="RD451_002804"
     CDS             1010..3259
                     /locus_tag="RD451_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HDT7567985.1"
                     /translation="MYKDNEMNIIYRSENQQFHLFNQEISYIFKISEDGKLLHLYYGE
                     NLPDNDYSHLIEMHHRPMTTYRNENDLLYSLEHLKQEFPEYGTTDFRHPAISLLQKNG
                     SRLSDFVYQGYEVEEGKPKLEGLPATYVDNNDESKTLKVYILDSVTNVQVELLYTIYR
                     DYPVITRSARVMNKGKDIQIIENISSLSLDLPDANYEWQQLSGAWGRERTIKSRTLQQ
                     GIQSIESTRGISSHQHNPFVTLKRKNTDENQGEAIGAALVYSGNFLIQAEVDTWDVTR
                     LQVGINPFGFNWKLNPGEIFTAPEAILVYSSKGLNAMSQTFHQLFRKRLARGKWREKD
                     RPVLINNWEATYFDFDEEKLVNIAKKAFDVGIELFVLDDGWFGERENDCAGLGDWHVN
                     PKRLPRGIGSLSEKIRSFGMKFGLWFEPEMVNKDSELYGTHPNWIISTPNRKPNHGRN
                     QYVLNFGLDEVVENIFDQMCKIIDESNLDYIKWDMNRPLTDVFDSHLSADQQGEVFHR
                     YVLGVYRLYEKLITKYPNILFESCSSGGGRFDPGMLHYAPQAWASDDSDAIERLKIQY
                     GTSMLYPLSSIGAHVSIVPNHQTNRITPIKTRGNVAFFGAFGYELDLNELSEGDLRIV
                     KEQIAFYKKYRTIIHNGTFYRLLSPFDDDNQTAWMVVSHDKKTAIVAHYKTLNEVNAP
                     YRRLKLKGLDNDGLYNVGQNSLRSGMELMRAGLVCSDASSGQINDQNRRPETFDFDSK
                     IWVITQEEK"
     gene            3262..>4416
                     /locus_tag="RD451_002805"
     CDS             3262..>4416
                     /locus_tag="RD451_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDT7567986.1"
                     /translation="MNNQKSLLQKGAILSISLMLTSSQAINGVIPQMKQSLGISQSQS
                     ELLGTAPSITVILFILLSSYFAKRIGMKKTIILGLLLAGIGGIIPVFTATFQTVLISR
                     VILGAGLGVYNSLAVTYISSLYSGNTRATLLGIRNSMEALGQTILIFLAGVLVNINWT
                     ASFLVYAIAFPVALLFALKVPEIRDENSDIPENHVKEKMNPMVFALVLFAILLVMNSI
                     AISVRFASIATEIKGVNFNASNYLALMPILGILAGFMFGPINKWIGKGTLYLGIIFFI
                     ISNLLIAVSNGNMTFLLTGLFLSSITGSWCFPFIFSNLDKVTTKNTINFATSLIFIGC
                     NIGNFIAPIAMQLAQFLTRSTNLTAPFFVFAGIFIVILFVTFFATNKKNTR"
BASE COUNT         1556 a          624 c          807 g         1429 t
ORIGIN      
        1 gtaataatat aaacataata aaacaaaaat tatccaaatc taacatagga gggtggatat
       61 ggaaaattct atatatttag taacagaacc taacactcag ctgaaagatt gttactttaa
      121 tttttgtggg tattcaaaaa cagaacctag acatagtttt ggaccagcta ttcgagaaca
      181 atacttaata cacatagtgc tagaaggtga aggctattat tcaattaatg atcaaaaata
      241 ttttctgaag aaaggccaag gatttgttat cccaccagga gtatctactt tttatcaagc
      301 agatgaaaaa aatccgtggt catatgtatg gttgggttta agtggcaatc ttgtagaata
      361 ctatctaaaa gaaattggtg ttggaaagaa tcatcttacc tttaaagtcg aaaatttaaa
      421 ttcatttaaa ggattaattt ttgaaacttt atcgtatgat caggacaatc tagtcagtga
      481 attgtccaga caaaaacaag tttataaatt tttagaactc ctcttaaatt cagctagtta
      541 tctgaacgaa gggataatta ctaaaaagat gaatcctttt gttcgtcaaa caattgaaat
      601 aatacgtgag aatgcgtatc aaaaattatc tgttaaagat attgctgtca gtctatcgat
      661 acacgaaaat tatttatcac gattgtttaa gaatgatatg ggaatatcaa taaaagagta
      721 tattagtgaa atcaaaattt ctattgcaaa cgatctgtta tcatcaactg aatattcaat
      781 ccagcaaatc agtgacaaga taggattctc aacagtacaa tctttttcta aagcctttaa
      841 gaaagcaaat ggtgtttcac cgggagtata tcgaaaacgt agattaggtc taggaatcat
      901 taatggtgaa taaactaaac atttgatttt gataaatatt cgttacttta aacgcttact
      961 atttatgtga gcgtttttta taatgcaata aagaaacgga ggagagctta tgtataagga
     1021 taatgaaatg aatattattt atcgatcaga aaaccaacaa tttcatttgt ttaatcagga
     1081 gataagttac atttttaaga tatcggaaga tggtaaatta ttgcatttat attatggtga
     1141 gaacttacca gataatgact atagtcatct aattgagatg catcatcggc ctatgacaac
     1201 ctatagaaat gaaaacgatt tgctatattc gttagagcac ttaaaacaag aatttcctga
     1261 atatggtaca acagatttta gacatcctgc tatttcatta ctacagaaaa atggctctcg
     1321 cttatcagat tttgtctatc aagggtacga agtggaagaa ggaaaaccta aactagaagg
     1381 tttacctgct acctatgttg ataataatga tgaaagcaaa acattgaaag tttatatttt
     1441 agattcagtt acaaatgttc aagtagaatt attatataca atttatagag attatcctgt
     1501 tattactcgt agcgcgcgag ttatgaataa aggaaaagat attcaaataa tcgagaatat
     1561 tagcagttta tcattggatt tacccgatgc aaattatgaa tggcaacaat tatctggtgc
     1621 ttggggtaga gaaagaacta ttaagtcgcg tactttacaa caaggaattc aatcaatcga
     1681 atctactcga ggtatttcaa gccatcagca taacccattt gttactttaa aaagaaaaaa
     1741 tactgatgaa aatcaaggag aagctattgg tgcagcacta gtttactcag gaaacttctt
     1801 aattcaagca gaagtagata catgggatgt tactagacta caagttggca tcaatccatt
     1861 tggatttaat tggaaactca atccaggaga aatatttaca gcaccagaag cgattctggt
     1921 ttattcaagt aagggtttaa atgccatgag tcaaactttt catcaactat ttagaaaacg
     1981 cttagctcgt ggtaagtggc gagaaaaaga ccgtcctgtc ttaattaata attgggaagc
     2041 aacatatttt gattttgacg aagaaaagtt ggtaaatatt gctaaaaaag catttgatgt
     2101 tggtattgaa ttatttgtat tagatgatgg ctggtttgga gaaagagaaa acgattgtgc
     2161 aggattagga gattggcatg taaatcctaa aagactacct agaggaatcg gcagcctttc
     2221 agaaaaaatt cgtagttttg gtatgaaatt tggtttatgg tttgaacctg aaatggtgaa
     2281 taaggatagt gagttatatg gcacacatcc gaattggatt atttctacac ctaatcgaaa
     2341 acctaatcat ggtaggaacc aatatgtatt aaattttggg ttagatgagg ttgttgaaaa
     2401 tattttcgat caaatgtgta aaatcattga tgaatcaaac ttagattaca ttaagtggga
     2461 tatgaatcgt ccattgactg atgtatttga cagtcacttg tcagcagatc aacaaggaga
     2521 agtattccac agatatgtac taggcgtata tcgcttatat gaaaaactta taacaaaata
     2581 tcctaacata ctatttgagt cttgttcatc aggtggtggg cgctttgatc ctggaatgct
     2641 tcactatgca cctcaagctt gggctagtga tgattcagat gcaattgaaa ggttaaaaat
     2701 tcaatatgga actagtatgc tgtatcctct ttcgtctatt ggtgctcatg tatcaattgt
     2761 tccaaatcat caaacaaacc gtataacacc tataaaaact agaggaaatg tagctttttt
     2821 tggtgcattt ggatatgagc ttgacttaaa tgaattaagt gaaggcgatt tgaggattgt
     2881 aaaagaacaa attgcctttt ataaaaaata tagaaccata attcataatg gtacttttta
     2941 tagactatta tcaccattcg atgatgataa tcaaaccgcg tggatggttg ttagtcatga
     3001 taagaaaacg gctattgttg ctcattataa aacattaaat gaggtaaatg ctccttaccg
     3061 ccgactgaaa ttaaaagggt tagataatga cggactttat aatgtaggac aaaatagttt
     3121 gcgatctgga atggaattga tgagagcagg actagtctgt tcagatgcat ctagtggaca
     3181 aataaatgat cagaatcgac gcccagaaac atttgatttt gattccaaga tttgggttat
     3241 aacacaggag gaaaagtaga gatgaataac caaaaaagct tacttcaaaa aggagcaatc
     3301 ttaagtattt cactaatgtt aacaagctct caagcaatta atggtgttat tccacaaatg
     3361 aaacagtctt tggggatatc acaaagtcaa agtgaacttt taggaactgc accaagtata
     3421 actgttattt tgtttatctt attatctagt tactttgcca aaagaatagg aatgaaaaag
     3481 acaataattt taggtttatt attagctggt ataggaggaa ttattccagt atttacagct
     3541 accttccaaa ccgttcttat tagtcgagta atattaggtg ccggtttagg agtatataat
     3601 tcattggctg tgacatatat cagctcttta tactctggca atactagagc aacgctatta
     3661 ggtattagaa attcaatgga agctttaggt cagacaatcc ttatttttct tgctggagtt
     3721 ttagtgaaca ttaattggac ggcttcgttt ttagtctatg caattgcgtt tcctgtagct
     3781 ctcttattcg cgctaaaagt tcctgaaatt agagatgaaa atagtgacat acctgaaaat
     3841 catgtaaaag aaaagatgaa tccaatggtt tttgccctag ttctatttgc aatcttactc
     3901 gtaatgaata gtattgctat ttctgtacga tttgcatcaa ttgcaactga aattaaaggg
     3961 gtaaacttta atgctagtaa ctatttagct ctaatgccta tcttaggaat actagcagga
     4021 tttatgtttg gaccaataaa taagtggata ggaaaaggaa ccctatactt gggaattata
     4081 ttctttataa tttcaaattt gttaattgct gtgtcaaacg gtaatatgac gttcctgcta
     4141 acgggtttat ttttatcaag tataacagga tcatggtgct tcccatttat ctttagtaac
     4201 ttagataaag tcactacaaa gaatacaatt aattttgcta cttcattgat ttttattggc
     4261 tgtaatattg gtaattttat agctcctatt gctatgcaat tagcacaatt tctaacaaga
     4321 agtacaaatt tgactgctcc attttttgta ttcgcaggaa tatttattgt gatcctattt
     4381 gtaacatttt ttgcgacaaa taaaaaaaat actaga
//
LOCUS       DAPBAF010000100         4372 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.106, whole genome shotgun sequence.
ACCESSION   DAPBAF010000100 DAPBAF010000000
VERSION     DAPBAF010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4372)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4372)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4372
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.106"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(83..1051)
                     /locus_tag="RD451_002806"
     CDS             complement(83..1051)
                     /locus_tag="RD451_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HDT7567987.1"
                     /translation="MSKKRTIVNEWEKLTALSNRRLNVQTLVQTIKLNWSIDRITIVG
                     KLNQNIFYHTQHDVLILDFEQLMRVNEGNGYLKAVGNNGWQLLDQHDENIAYIEISKW
                     QEGKGRIDFNPNKISRFLADSMKNFIHDLFLEPHFSRADVACDLIDVPDEFITQYRII
                     DPVSFKLIYGRSGKLETVYWGSRASERQIRLYNKKIEQEMKRKVVPSEINTWWRLEMQ
                     LRRGKATEWYAMVKESLDSFVSPHFLPTDIKPTDKVMIDGLLANHSNWAILSRNSKYK
                     YRNLLKRESQNDELTNHLRETFEESADDLKKELDTWLQGLDVTEEE"
     gene            complement(1496..2902)
                     /locus_tag="RD451_002807"
     CDS             complement(1496..2902)
                     /locus_tag="RD451_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HDT7567988.1"
                     /translation="MGFSISFKKGTKNTSISHNNRELTDRQKTNDWHKHIDFTKSDEN
                     IYLEQTNLADKYEELFGEVVEKYNAKQKRADRKIEDYLAKVRKDKKLEPQREFIVQIG
                     ILDDFQTNRADGSSTGISKQQAEQNRVIANKILVQYYKEFQERNPNLAVYNAVIHNDE
                     ISPHLHLNIVPVAEGYKRGVQKQPSFNKALVQQGIHADKDNGRVLFNNFRNQEVDSIE
                     RLMNDYGWKRDIVGTNKIKDIHEYKEIMSEISELRQTAVKERESVSDELRYIYRQREE
                     NERDKALMASERAKIEEEKKNMLNVKKEMAVIFQKDMVPLESFKRLPDGSYHLSGNDF
                     VDLYQRATRATNAKRNADNMSEQYLQMLEQNTELNEYVATLEEERHLSGRKQLADLQV
                     ENKKLKEENRSLRQRLERLKNAFQKSITRLSIRFGLAEKDMGLSEELEVLEQEKTLFY
                     RQNVSQHKLERSENEIEW"
     gene            complement(3124..3486)
                     /locus_tag="RD451_002808"
     CDS             complement(3124..3486)
                     /locus_tag="RD451_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567989.1"
                     /translation="MGMTLADIKAQEEKLKKEQAKLRQQKKRLIEKENAAMGKALRKR
                     FGFETFADFERWLSSISDDQQHEKTVDNEWLADEKSAPSERDYPDESDDLFGVIPNKK
                     SQMSESKFTSIFNDVNLR"
     gene            complement(3490..3828)
                     /locus_tag="RD451_002809"
     CDS             complement(3490..3828)
                     /locus_tag="RD451_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567990.1"
                     /translation="MVAILEVRCDMDKIDLREETVDRIELMYERLADYLNLPDEDNYS
                     EMLERIMDVLNSVINADLAKSSVLTNEFVHKHLAQTTDESEKEFWLKLMSHVMQLNQI
                     SVINSKEKEM"
     gene            complement(3807..4226)
                     /locus_tag="RD451_002810"
     CDS             complement(3807..4226)
                     /locus_tag="RD451_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567991.1"
                     /translation="MTDLPEKMTIKNLADELGISKNTVRNQLVNAGYDLARYKDNGVI
                     MLDKELIGVVRSIYRSKGGQLTGDLPVNDAGNDFPLEKENEFLREQLAEKDRHISELT
                     EMIRDQQKLTLLQQQKNDQLLLENQELKNRKWWQFWK"
     gene            complement(4219..4359)
                     /locus_tag="RD451_002811"
     CDS             complement(4219..4359)
                     /locus_tag="RD451_002811"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567992.1"
                     /translation="MSGKLLDVTQYELILKNNKIDSPIIIPKHAVKYVYGVAESNGED
                     ND"
BASE COUNT         1241 a          979 c          604 g         1548 t
ORIGIN      
        1 aaaaaaacaa cgacaacgtt atcacctgtt aaattcacca accaattttt cttaccaaaa
       61 tgcttttgtt tttctgccat tactattcct cctctgtcac atcaagtccc tgtaaccaag
      121 tatccaattc tttttttaaa tcatctgctg attcttcaaa tgtttctcgt aaatgattcg
      181 tcaactcatc attttgactt tctcgcttta ataaatttcg atatttatat ttcgagtttc
      241 ttgacaaaat cgcccaatta gaatgattag ctaacaatcc atcaatcata actttatccg
      301 taggttttat atcagttggt aaaaaatgtg gactcacaaa gctatccaaa ctttctttca
      361 ccatagcata ccattccgta gctttaccac gtcttaactg catttctaac cgccaccaag
      421 tattaatttc tgaaggcacc acctttcttt tcatttcttg ctctattttt ttattgtaca
      481 aacgaatttg ccgctcgctt gcccgactac cccaatacac cgtttccagt tttcctgagc
      541 gtccataaat taatttaaat gaaactggat caataattcg atattgcgtg ataaactcat
      601 caggcacatc aataagatcg caggcaacat ccgctcgtga aaaatggggc tctaaaaata
      661 aatcatgaat aaaatttttc atggaatccg ctaaaaatcg actgatttta ttaggattaa
      721 aatcaatccg cccttttcct tcttgccatt tagaaatttc aatataggca atattttcgt
      781 catgttggtc taatagctgc caaccattat ttccaaccgc ttttaaatag ccattgcctt
      841 catttacccg cataagctgt tcaaaatcta atattaatac atcatgttga gtatgataaa
      901 aaatattttg attcaacttt ccaacaatgg taattcggtc aatcgaccaa tttaatttta
      961 tagtttgtac caaagtttga acatttaacc gcctgttaga cagggctgtt aatttttccc
     1021 actcattcac gattgttctt tttttactca tattcagttc ctcctcaaag aaaaaagaga
     1081 tttttggaaa gaatttccag agttcacgta actctaaaaa ttcataacca tcaatctcta
     1141 gtcttgaaga aacctaaaaa tattcgtata atgaatttga gttacggaac tagtgtggtt
     1201 agtttccgta aaggtcgaga acgttggtag cgttgctcga cttatttttt tgctcttttt
     1261 ccagttcatt tgtttgctaa ctcaataata gcacttctct ttagctatgc aaataccaaa
     1321 aaaataaaac cgcacccttt gaaaagggcg cccccaaact tcgctaacgc taagttggcc
     1381 aaaaaatgga cttgccattt tttagcaaat gtcagcttca ggggctagtg gtttagccgt
     1441 caactcctta tcctcggcac aaaccgcctc cggtaccgtt gactgcacat cgtggctacc
     1501 actcaatctc attctcagaa cgctctaatt tatgctgtga gacgttttga cgataaaata
     1561 aggttttctc ctgctctaat acttctaatt cctcagaaag ccccatatcc ttttctgcaa
     1621 gaccaaaacg gatagacaaa cgagtgatcg atttttgaaa tgcgtttttt aatcgctcta
     1681 aacgctggcg taaagagcga ttttcttctt tcagcttttt attttccact tgtaaatctg
     1741 ctaattgttt tctaccagac aaatgacgct cttcttccaa tgtagctaca tactcattta
     1801 attctgtatt ttgctcaagc atctgtaaat attgctcact catgttatca gcatttctct
     1861 tggcatttgt tgctctcgta gctcgttgat acaaatcaac aaaatcattc ccagataaat
     1921 gatacgaacc atcaggaagc ctcttgaaac tttctaaagg aaccatatct ttttggaaaa
     1981 tgaccgccat ctcttttttt acattcagca tatttttctt ctcttcttca atcttcgctc
     2041 tctcagaagc catcagagcc ttatcacgct cgttttcttc tctttgccta taaatatacc
     2101 tcaactcatc agaaacgctc tcacgctctt ttacagccgt ttggcgcaat tcagaaattt
     2161 cactcatgat ttctttgtat tcgtgaatat ctttaatttt gttggtaccg acaatatccc
     2221 ttttccaacc gtaatcattc attaatcgtt ctatagagtc aacttcttga tttctaaaat
     2281 tattgaaaag cactcgacca ttatctttat cagcgtgtat cccttgttga accagtgctt
     2341 tattaaagct cggctgcttt tgaacacccc gtttataacc ttcagcaacc ggcacaatat
     2401 tcaagtgcag gtgcggactt atttcgtcat tatgaataac agcattataa acagccaaat
     2461 tagggtttct ctcttgaaac tccttgtaat actgaaccaa aattttattg gcaatcactc
     2521 gattttgttc agcttgttgt ttcgatatgc cagtagaaga accatctgct cgatttgtct
     2581 ggaaatcatc taaaatgcct atttgcacaa taaattctcg ttgaggttcc aactttttat
     2641 ccttgcgcac tttcgctaaa tagtcctcga tttttctatc ggctcttttt tgtttcgcat
     2701 tatatttttc taccacttcg ccaaacaatt cctcatattt atctgctaga ttcgtctgct
     2761 ctaaataaat attttcatcc gatttcgtga agtcaatgtg cttatgccaa tcattggttt
     2821 tctggcgatc agttaactca cgattattat gagaaatact tgtattcttc gttccttttt
     2881 taaatgaaat actaaacccc aagttaaaac cctccttcgc gctgtcgcta ataaaaagat
     2941 tgtaaacctt tctgttactc tttgtcaaag agtaacattt tcctaattgt gacatggatg
     3001 tcacaattcc aaacgctctc cgagggtttt cgctgtcaca agtgacaacg aaaaaaggag
     3061 ccgaaagcgt atcacgctat caactccttt tatgctttat tttgcttcac gcaaaataat
     3121 cgcttatcgt aaattcacgt cattaaatat tgacgtaaat ttactctcac tcatctgact
     3181 tttcttattc ggtatcactc cgaataagtc gtcagattca tcgggataat ctcgttcgct
     3241 tggcgctgat ttttcatcag caagccactc attatccact gttttttcgt gttgctgatc
     3301 gtcagaaatt gacgataacc accgctcaaa atcagcaaaa gtttcaaacc caaaacgctt
     3361 gcgaagagcc ttgcccattg cagcattttc tttctcaatc aagcgttttt tctgttggcg
     3421 aagtttcgct tgttcttttt ttaatttttc ttcttgcgct ttaatatctg ctaaagtcat
     3481 tcccataaac tacatctcct tttctttgga attaataacg gaaatttggt ttaactgcat
     3541 aacatgactc attaatttca accaaaattc tttttctgat tcatcagttg tttgcgctaa
     3601 atgcttatga acaaattcat tagtcaaaac tgaagatttt gctagatcag cattgataac
     3661 cgagttgaga acatccataa ttcgttcaag catttcacta taattatctt catccggcaa
     3721 attcaaataa tcagctaacc gttcatacat caattcaatt ctatcgactg tttcttctct
     3781 caaatcaatt ttatccatgt cacacctcac ttccagaatt gccaccattt tcgatttttt
     3841 aattcttgat tttctagtaa caactgatcg tttttttgtt gctgaagcaa agtcaatttt
     3901 tgttggtcac gaatcatttc cgttaattca gaaatatgcc tatctttttc cgctaattgt
     3961 tcacgcaaaa attcattttc tttttctaac gggaaatcat tgcctgcatc attgaccggt
     4021 aaatcaccag tcaattgacc accttttgac cgataaattg accgcacaac accaatcaat
     4081 tccttgtcta acatgataac cccattatct ttataccgag caaggtcata acctgcattg
     4141 accagttgat tgcgcactgt atttttagat atacccaact catcagcaag gttttttatg
     4201 gtcatttttt ctggcaaatc agtcattatc ttctccgtta ctttcagcta ccccataaac
     4261 atatttaaca gcatgcttag ggataatgat tggggaatca attttattat ttttcaaaat
     4321 caactcatac tgcgttacat caagtaactt accggacatt tttttgctat cc
//
LOCUS       DAPBAF010000101         4155 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.107, whole genome shotgun sequence.
ACCESSION   DAPBAF010000101 DAPBAF010000000
VERSION     DAPBAF010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4155)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4155)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4155
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.107"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            177..773
                     /locus_tag="RD451_002812"
     CDS             177..773
                     /locus_tag="RD451_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HDT7567993.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
     gene            897..2696
                     /locus_tag="RD451_002813"
     CDS             897..2696
                     /locus_tag="RD451_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HDT7567994.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRPFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
     gene            complement(2974..3186)
                     /locus_tag="RD451_002814"
     CDS             complement(2974..3186)
                     /locus_tag="RD451_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567995.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPAELVS"
     gene            3648..3797
                     /locus_tag="RD451_002815"
     CDS             3648..3797
                     /locus_tag="RD451_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7567996.1"
                     /translation="MTFTKTNMQYRVAFDTTSNRFMAIDAQNENNVAFGITIEQAVRA
                     LNESR"
     gene            complement(4050..>4155)
                     /locus_tag="RD451_002816"
     CDS             complement(4050..>4155)
                     /locus_tag="RD451_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HDT7567997.1"
                     /translation="ASKRNNIPRKSLDYRTPLEVFLSYVSIDDLSNLI"
BASE COUNT         1229 a          707 c          728 g         1491 t
ORIGIN      
        1 taaaaaaaac aagttattaa ataagtcttt agttggatgt ttttttgaga tcaatctttt
       61 atacttatga tgaacttaca aaattgtttg ttttctgtca tatcaaaaaa tggcgcagtt
      121 agttgctttt ctagtaaagt atagttaaca aagaacctct aaggagttga tgaataatga
      181 atattgctgc ctctcgaaaa ctgataaatt tcatatccat tatcggatta ggcctatcaa
      241 tcgcgctgac gatttatttt attaatttag gtgttttcaa agatttgaat gcgttaagag
      301 gattagtagg tgattccatc attttaggac cgattatttt tgtcttcatc caaatcctgc
      361 aagtagttat tccaatcatt cctggaggga tcagtactgc agctggtgtc ctgatatttg
      421 gcccttatgc tggatttatc tataactata ttggaatctg cattggttcg attatcattt
      481 ttctgctagg gcgtcgttat ggaaagccat tcatactttc catgattagc gataagacat
      541 ataacaaata tattggctgg ctggataatc aaaaccgttt tgagaagctg tttgctctag
      601 ctatttttct tccagttgct cctgacgatg cgttatgttt gatggctgga ttgacaaaca
      661 tgtcagtgaa acgatataca ctaatcattt tgattgctaa accactgtcg attttcttat
      721 atagtatggc cttgatttat ggaggtcaat atctaagtgg tcttcttgga taatatttat
      781 tttgtaaaat tagtcattga ttgacaatgt taaatctggg aaagggtctg caaaacacac
      841 tgcacccttt cctttttcat tagatttgcg ctacaatgtg aagagcaggt gataggatga
      901 attatttgaa acgtagctta ggtaatgctt gggacttttt aaaaggaaca caagcttatt
      961 tccgtgatgt cttgctgatg catggcttta ttttatttat ttgtttaccc ttattgagca
     1021 gtacgacccg ttttatttta caccgagggg caattgacta tttgtcttat gacaatattc
     1081 cttcaatttt ttctcaacat cctggggttc tactctcgtt aatcgtagtt ttgatgacga
     1141 ttttactgtt agtttatttc gaatttactt ttcttttgat gagtgttttt tttattaaaa
     1201 agaaagaacc aatctctttg aagcaactct tacacttgac gatacttcag ctgaagaaag
     1261 tgagacccat tacttttttg tttttccttg cttatttttt attgattcta ccgatcagcg
     1321 gattaagttt taattctgat ctactgtcaa aaataaaaat ccccgctttc attatggatt
     1381 ttatttttgc taatcgttgg atcatcgtca gttccttttt actcgtttat attttccttg
     1441 gctatattgg gattcgactg atttttgctt taccggaaat gattctacga gatcgtcctt
     1501 ttcgagcagc cattcgggaa agctggtcat tgaccaaatc gcgtcttttg gccatcacgg
     1561 gccaatttat tgtgattggc ggtacgattt tactcctttc ttctttagga tatatcgttg
     1621 ttattttggc acaaagtatg gttgaacaat ttttcccaga ctatgcattg atcagcgctg
     1681 tgtttgctat gacgctttta caagggattt tattattcaa tatcgtgatg tctaccgtag
     1741 ggatttttta tatcattgtt gatttcatgg atgacgaagg cttcttgcct gagatcccta
     1801 agtggtttat cccacaagcc cccaacttgc gtttctctgc gctgaaaaac actggtttga
     1861 ctctttttgc agtttttttc ggtattggcg tctgtcttta caatatggat tatctgactt
     1921 cagctgttca gacaaaacca gtgactgtct ctcacagagg tgtgagtacc caaaatgggg
     1981 cgcaaaatac tttagaagca cttgaaaaaa caagcagaga ctatcatcct gattatgtag
     2041 agatggatgt tcaggaaaca aaagatggtc atttcgtagt gatgcatgat gcaaatcttc
     2101 gtcacttaac aggggtaaat ggaacaccac aggatcttac attgaaagaa ttgacaaatc
     2161 ttacagttac tgaaaacgga gtgcaagccc ctgtttgttc ttttgattct tatttggaaa
     2221 aagcacataa gctaaaccaa aaattactta ttgagatcaa gacctctaaa aaagattcgg
     2281 atgaccttgt cgaacgattt gtccataaat accgcaaagt tatcttagag aaccatcata
     2341 ttttgcaaag tttgacgtac caaaccgttt cagatttaaa agaagcagaa ccaaactttt
     2401 atgtgggcta catcttacct ttcaatattg ttgggccccc tgtgacgcct gctgattttc
     2461 tgacaatgga atatagtacg atcaaccgta acttcattaa ttctgcccac caagacggaa
     2521 aagaagtata tgtatggaca atcaacgatt cagatgctat gagtcgcatg atgttttatg
     2581 gtgtggatgg tatcataacc gatgagatgg gactactaaa tgaaagtgtg aaacaaacag
     2641 atgaagaaat cacttattca gataaactgc taaattttgt tttgggagtc ggctaatcaa
     2701 aaatcgttaa tgaaaaaagt ctttatacaa caaaaaacgc ataacctgcc accgcaggta
     2761 tatgcgtttt ttgtttgacg ctcataatgt gtgcttaact ttctcttgat tccttcatcg
     2821 cacgaacaat agctaaaata gcaggaattg cagagatcac tgcaagaata attcccattt
     2881 tccctgaact ttttcttttt ggcatatctt ctcgctccct tctgtcttta tttatattat
     2941 aagggagttc ttgcgaattc tcaaaaatac tgtttaagaa accaattcag caggtgcgct
     3001 aatatcacag aattttacga gcatgcgata cttgctttca ttgataagtt gatagtctcg
     3061 ttggtcataa ctttcaacat acacgacagc cgtgttgata tatgtacgtt caatacagcc
     3121 gattagttca tgagatactc cgatcggttt gcatatataa gatcttccta cttctgcttt
     3181 taccatttca ttccctcttt tctttatttt tattttgttt tttctttatt ttataataac
     3241 aaattacctt gtatttgaaa acgtttttat ccattttttt attttttatt ttgagtatct
     3301 ttctgctttt tagataacta ttttttaaca cgatcttaga cgttgtgaca aaaacgtttg
     3361 tttatattcc tatgttgttc gtgcgttttt ttctttatat tgctaagtta tttataaaga
     3421 ggtgagcata tgatttatat tcaagcaata gtatttgtaa ccttgatgat tgggctactt
     3481 atcggattaa aagaaaatag ctaaaccatt taagaaaaaa taaataagga aaatgataaa
     3541 tgctttttaa ttgcatcaaa aaacgtacga tgctaaactt ggtataagtt cgaaagttta
     3601 aaggaaactt tcaagaacta aattacatta caaaggagat gaattttatg acgtttacaa
     3661 aaacaaatat gcaataccgc gtagcttttg atacaacttc taaccgtttt atggcgattg
     3721 atgcacaaaa cgaaaataac gttgcgtttg gtattacaat cgaacaagca gtccgagcat
     3781 taaacgaatc tagataagga gtgaaccatt ccaaatggcg actgatgaga tctcggaaaa
     3841 tcaataaaag acgtttgtaa cggtaatccg cgacaaacgt ctttttgtat tcattacata
     3901 tatttggaaa ttgtctctct ttatctctag acctaaacaa aaacacaagt tctaatatca
     3961 accatctcgt tttttatgac aattttgtta gctgtttcga tgataatatt ccgttattat
     4021 ctgtataata tttaatataa tcttaattgt caaattaagt tagacagatc atcaatactt
     4081 acgtaactca aaaatacttc caaaggtgtt cgataatcca gtgattttct aggaatatta
     4141 tttcgtttag atgcg
//
LOCUS       DAPBAF010000102         3901 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.108, whole genome shotgun sequence.
ACCESSION   DAPBAF010000102 DAPBAF010000000
VERSION     DAPBAF010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3901)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3901)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3901
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.108"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(152..427)
                     /locus_tag="RD451_002817"
     CDS             complement(152..427)
                     /locus_tag="RD451_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgO"
                     /protein_id="HDT7567998.1"
                     /translation="MALLPTNKDKKKIGAEDISIKDDINVELGERKYTAKERKPVQVD
                     PPVLKTIRDLSYAKDIPMYEIVKLAMDAYVDTLNDEERIIYNRRSKD"
     gene            complement(399..1352)
                     /locus_tag="RD451_002818"
     CDS             complement(399..1352)
                     /locus_tag="RD451_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HDT7567999.1"
                     /translation="MENLRTAFKTSDKLGKVVMLTGRKGGIGKTTDNDLLAIVSSQLF
                     EKDVLLIDYDQQRNTTSNIGSTYQITSFDRSMSAAIKKGDWVSGITQVSPHLYIMAGS
                     PGSEELNEYLSEKYPDRRKRSLAFIKPLEELRKNFDYIFIDCPPSTDNVVRAFLTAAD
                     YIIAMQELKRYAMEGTEDFINKVLVPIVTNFEESHLQIIGILPVLFSVRRSSQHANYQ
                     KTIDKYGESNIFKSIVKGSDRLEMYGENGIQLNDYVDRRWWAIFADIFTELEERIEYY
                     EQHGDIEGFDYTPKYADSMANHILPLGKEIKLNGIITNEQR"
     gene            1964..3457
                     /locus_tag="RD451_002819"
     CDS             1964..3457
                     /locus_tag="RD451_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase C-terminal domain-containing protein"
                     /protein_id="HDT7568000.1"
                     /translation="MLSEIYSAILKNGLRTYKYRNSTMKPAGHIDSSRSGAIFAYRSK
                     QLMNVGRGMVITSEEAILENEKKLTHWTPNTYRFGTYADDYRTVVKGHSEKNLSQINT
                     FVVDIDSKENHQGEIILACLDQVGYMPTLILESDHGYQVYFVLKTPGYVTKKSNFKVI
                     DVAKKISKTIRLQLAEKLSGVDLGCNHFGIARFPQENNIVFKEMNYQYSFADWIQWSM
                     KLESDQKTKEDRERKLIVFPEKKEIRQVDEPWFDMLLHKANIVGGEGRLGRNNVIFTL
                     SLAYYSSGYALDTCEYNMFTFNERLQEPLSEAELVKIVRSAYSGNYQAASREFIIELC
                     QQWVSPTLKNNDLFIQRRGWWKFKKPRDQRKYSHKNEWKEDLLAYLSEKSLASEPYLN
                     LSKKELASQLTMPKRTLDKILNELREENKVFYKVTRGRNGGMIIASVKTLFARVIQLS
                     KEKRLDYSTRITEVFGLNESLVEETFRQLSTPLNPLKEVNLFEVDTG"
     gene            3592..3888
                     /locus_tag="RD451_002820"
     CDS             3592..3888
                     /locus_tag="RD451_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HDT7568001.1"
                     /translation="MSLKNYVYSHPVNVFIIGRLGLSVEVFCELYGFKQGTLSSWVTR
                     EKTVASLPIEFLHGLSLASGETMDQVYDCLCVLEQEYIEYKIANELRKRKKYIQ"
BASE COUNT         1300 a          635 c          704 g         1262 t
ORIGIN      
        1 atttagtata gtaaaaacta gaaacaataa aatttgtgaa tgttgtatac ccccaaacaa
       61 tacacatatt ttgaaggatt aggattaata aagctaaaaa tatagtaagt atactaaata
      121 tatttactat atctagtata cttactatat tttaatcttt tgatcgtcta ttatatataa
      181 tccgttcctc gtcgtttaaa gtatcaacat aggcgtccat tgcaagtttg actatttcat
      241 acataggaat atcttttgca taactaagat cccgaatggt ttttagtacg ggaggatcta
      301 cttgaactgg ttttctttct ttcgcagtgt actttcgttc ccctaactcg acattaatat
      361 catctttaat tgaaatatct tcagcaccaa ttttcttctt atctttgttc gttggtaata
      421 atgccattta gtttaatctc ctttccaaga ggtaggatat gattggccat tgagtcagca
      481 tatttaggtg tataatcaaa tccttcaata tcaccatgtt gttcatagta ttcaattctt
      541 tcttctaatt ctgtaaagat gtctgcaaaa atagcccacc atcttcgatc tacataatca
      601 tttaattgga taccattctc accatacatt tctaaccgat ccgagccttt aacaatgctt
      661 ttaaaaatgt ttgattcacc atacttatca attgtttttt gatagtttgc gtgttgagag
      721 gaacgtcgca ctgagaaaag aacaggcaaa attccaatga tttgaagatg agactcttca
      781 aaattcgtga caatcggaac taaaacttta ttaataaaat cttctgttcc ttccattgcg
      841 taccgtttta attcttgcat tgcaataata taatctgcag cagttaagaa tgcacgaacc
      901 acattatctg ttgatggtgg gcagtcgata aagatataat cgaaattttt tctcaattct
      961 tctaaaggtt taatgaaggc caatgatctc ttacgacgat caggatattt ttcggacaag
     1021 tattcattaa gttcttcaga tccaggagag ccagccataa tatataaatg tggacttact
     1081 tgagtaatac ctgaaaccca gtcccctttt ttgattgctg cagacatgga tcgatcaaag
     1141 ctagtaattt gatacgttga tccaatgttg gaagtagtat ttctttgttg gtcataatca
     1201 attagcaaca cgtctttttc aaaaagttga ctagaaacaa tcgctaataa atcattgtct
     1261 gtagtcttac caatgccgcc ttttctacct gtaagcatta caacttttcc tagtttatct
     1321 gatgttttaa atgcagtccg taagttttcc atagttccct ccaatttcct atactaaata
     1381 tatttagtat acttcatata cttaatatat tcgatatatc taatatactc caaattgata
     1441 agaattcaga ctttataagg aatatagtgg atatactaaa tatatttgct atattcagta
     1501 tatcagatat attcaaaatg tcaaaatata tttgtgcgtt ttgcgttgac aatttagagt
     1561 gaaaagaggt aaacttaatt ctatagaaac cacagataat tcactattta caaagtagca
     1621 aaagcagtgg tactctttaa acagaaaaat tacataaaaa aaagagacgg aaataattga
     1681 ttttagcaga atcaattatt tctgaatcac atggttagga catgtgttca cgctcgtctc
     1741 aagaatatgt aagtagctac caactactta tattaaaagt tgatcggata ccttttccga
     1801 ttgcctttat tctaccaaaa aaaggcgagc aactcaacag aagaacgttt atttagtgta
     1861 cttaaattaa atattcttaa acactgaaga gagaacacat actatggctg agattaaagc
     1921 taaactgtgt tctctttttg tttgagaaag gacgttacaa tcgatgttga gcgaaattta
     1981 ttcagctatt cttaaaaacg gcttacgtac atacaaatat cgaaacagca ccatgaaacc
     2041 tgcaggtcat attgattcca gtaggagtgg tgctatcttt gcgtaccgta gcaagcaatt
     2101 aatgaatgtt gggcgtggta tggtcattac ttcggaagaa gctattttag agaacgaaaa
     2161 gaaactaacg cattggacac ctaataccta tcgctttggt acttatgcgg atgattatcg
     2221 aacagtggtt aaaggtcatt ctgagaaaaa cttaagtcaa atcaacacat ttgtagttga
     2281 tatcgattca aaagagaacc atcaaggcga aattatttta gcctgtttag atcaagtggg
     2341 ctacatgcca acgctaattt tagaatcaga tcatggttat caagtttatt ttgtactaaa
     2401 gacaccaggc tatgtcacaa agaaaagcaa tttcaaggtg atcgatgtag caaaaaaaat
     2461 ttcaaaaaca attcgtctac agttggctga aaaattgtcc ggagtggatc taggatgtaa
     2521 ccacttcgga attgctcgat tcccacaaga aaataatatt gtttttaaag aaatgaacta
     2581 tcagtattct tttgctgact ggattcaatg gtcgatgaag cttgaatcag atcaaaaaac
     2641 aaaagaagat cgagaacgaa aactaattgt ctttcctgag aaaaaagaaa ttcgtcaagt
     2701 agatgaaccg tggttcgata tgttacttca taaagcaaac atcgtcggcg gagaaggacg
     2761 tcttggtcga aataatgtga ttttcacgct ttctttagct tattactctt caggttatgc
     2821 attggatact tgcgaataca atatgttcac attcaacgaa cggttacagg aaccgctatc
     2881 tgaagcagaa ttagtaaaga ttgtacgtag tgcttattct ggtaattatc aagcagcaag
     2941 cagagaattc attattgaat tgtgccagca atgggtttca ccaaccttaa aaaataatga
     3001 tctgttcatt caacgacgtg gctggtggaa atttaaaaag ccacgagatc aaagaaaata
     3061 tagtcataaa aatgaatgga aagaagatct attggcttat ctaagcgaaa aaagtcttgc
     3121 tagtgagcct tatttgaacc tgtcaaaaaa agaattggct tcacaactaa cgatgcccaa
     3181 gcgaacactt gataagatct taaatgagtt acgagaggag aataaagtct tctacaaggt
     3241 aacacgagga agaaatggcg gaatgatcat tgcttcagtc aaaacgttgt tcgcgagggt
     3301 tattcaacta agtaaagaaa agagactaga ttattcaaca aggatcacag aggtatttgg
     3361 actcaacgag agcttagtag aagagacatt tagacaatta tcaaccccct tgaaccctct
     3421 taaagaagtg aatctttttg aagtagatac aggttgaaaa ataaaaggtg caaattgcct
     3481 tatacaatat atctatgata cttctgtagg tgttgctccc tttgcctagc tacgtgtagg
     3541 tggtatactt ataactgcgt atgcagtctt atgtatcatg gaggaagttg tatgtcgtta
     3601 aaaaattatg tctattcaca tcctgttaat gtgtttatca ttggtcgttt gggattatct
     3661 gtggaagtgt tctgtgagct ttatggtttt aagcagggga ctttgtcttc ttgggttacc
     3721 agggaaaaaa cagttgcttc tttgccgatt gagtttcttc atgggttgtc cttagcttct
     3781 ggggagacta tggatcaggt atatgattgt ttgtgtgtgt tagagcagga gtatattgag
     3841 tataaaatag ctaacgagtt aagaaaaagg aagaagtata tccagtagta gtttttattt
     3901 a
//
LOCUS       DAPBAF010000103         3895 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.109, whole genome shotgun sequence.
ACCESSION   DAPBAF010000103 DAPBAF010000000
VERSION     DAPBAF010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3895)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3895)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3895
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.109"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(<1..355)
                     /locus_tag="RD451_002821"
     CDS             complement(<1..355)
                     /locus_tag="RD451_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7568002.1"
                     /translation="MKKFKKKIYLGLVVGVSMFGFMAHTKQVTADTNQKERIMSQLDD
                     SQIEYVPNELIVSLKATQRISTEKNKPQNLLGVKVMVEKDLTLRINESDYNKRDQVLL
                     VKLNEEISVEEAVRTF"
     gene            complement(615..1163)
                     /locus_tag="RD451_002822"
     CDS             complement(615..1163)
                     /locus_tag="RD451_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7568003.1"
                     /translation="MADIKGLDIFGNNKGLAKIKKEAEAKKKQQAITPSENKQLEVHQ
                     VQEIKTSSNVERQSRGRTKKVGAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETN
                     MTRDELLRKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTT
                     SQIKQDTEDSLRKGWGMNNKVR"
     gene            complement(1164..2021)
                     /locus_tag="RD451_002823"
     CDS             complement(1164..2021)
                     /locus_tag="RD451_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HDT7568004.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYSKSAMYIA
                     DWAIVVLQTQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVDQEMYKQ
                     AQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISILKELEE
                     HENWYAEVE"
     gene            complement(2307..2593)
                     /locus_tag="RD451_002824"
                     /pseudo
     CDS             complement(2307..2593)
                     /locus_tag="RD451_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(2583..2912)
                     /locus_tag="RD451_002825"
     CDS             complement(2583..2912)
                     /locus_tag="RD451_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HDT7568005.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
     gene            complement(2989..3261)
                     /locus_tag="RD451_002826"
     CDS             complement(2989..3261)
                     /locus_tag="RD451_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HDT7568006.1"
                     /translation="MNNYSVMIKNSAKADLKKIKQSNLKPQFEKVIQTLKEDPYLPTQ
                     SFEKLKPTHEGRYSRRLNRQHRVVYKVDEDEHVVEIYSARTHYESQ"
     gene            complement(3261..3524)
                     /locus_tag="RD451_002827"
     CDS             complement(3261..3524)
                     /locus_tag="RD451_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HDT7568007.1"
                     /translation="MAKTVLNPSSARKNFYKLLKDVNENHTEIEIISERSENNAVLIG
                     LDDWKAIKETLLLEQIGTLGVVRKREKDDSGFTNVDEIDWDNL"
     gene            3758..>3895
                     /locus_tag="RD451_002828"
     CDS             3758..>3895
                     /locus_tag="RD451_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HDT7568008.1"
                     /translation="MRSSKYTEHYTDTFITFKEIMRTVSNIYHNCVPDKIKNRRNTDQ
                     LK"
BASE COUNT         1166 a          784 c          498 g         1447 t
ORIGIN      
        1 taaatgttct tactgcctct tccacactaa tttcttcgtt caatttcact aataatactt
       61 gatctcgctt attataatcg ctttcattta tcctaagagt caaatctttt tccaccataa
      121 cttttacacc caataaattt tgcggtttat ttttctctgt tgaaattctt tgtgtagcct
      181 ttaaactgac aattagctca ttgggtacat actctatttg agagtcatct aattggctca
      241 taatcctttc tttttggtta gtatctgcag ttacttgttt agtatgagcc atgaacccaa
      301 acatactcac cccaacaacc aatcctaaat atattttctt tttaaacttt ttcatctaca
      361 tctcctccta atagttttat tttagagtta gctctattac ttatttacta actcaacaac
      421 agattatcat acacttgtta atgaaatcac aatatctcat taaaacacac cctaaaatca
      481 taaccgttcc tatgctcatt ttttggattt tttaatcacg taaccagaaa aataaatccc
      541 ctctatttca cgcaaatcaa agaagaacta agtaactacc gtttaaaggt agttacttag
      601 ttcttctttg attattatct aactttatta ttcattcccc accctttgcg cagtgagtct
      661 tcggtatctt gttttatctg actggtagtt cttattattt ctccacgatc atctaattct
      721 ggaacaattg gatatttttc tctgaacaag tctagttctt tcaccacgtc attaaacaaa
      781 tcttgcttat cttcttgcgt aagattctgt ttaatatact catctaaagc ttttctaagc
      841 aattcatctc ttgtcatatt agtctcatac ttttctacta aaactctgga agtcgcattt
      901 aacaaagtcg acagttttaa aggatgcttg gtggaataaa ccttatcaaa ctttctgatt
      961 ggtgcgccaa ctttttttgt tcttcctcta ctctgtcttt caacattgga ggaagttttt
     1021 atttcttgaa cttggtgcac ttctaattgc ttattttcag atggtgtaat tgcttgctgc
     1081 tttttctttg cttctgcttc tttttttatt ttggcgagtc ctttgttgtt cccaaaaata
     1141 tcaagtcctt tgatgtcagc caattactcc acctccgcat accaattctc gtgttcttcc
     1201 aattctttca aaatactgat aaataattcg tggcttttgc gatcccattg ttttaagaga
     1261 cctttctttg tcttctccat cgtaatacct gatccgtcgt atcgttttaa gcgcgcattt
     1321 ttgagtacaa catttttaat caaatgttcc ccataaatct cttgggcttg tttatacatt
     1381 tcctgatcta ctgcgtcacc gctttccaac atgaaaggaa taacaccagc aacatataaa
     1441 tttgtatcaa attctttcac aaaaaagtcc atatactcaa gatattgcat cgcatttctc
     1501 atcgatttta cttgggtctg taagacgacg attgcccaat ccgcaatgta catcgcggat
     1561 ttactatata cagaaataga aggtgggaca tctaaataga tgacgtcaaa ctcatcaaat
     1621 aatggttcta gcttttcttt catatatttg aattgggata atgaatcatt atattggtct
     1681 ttgatccaat catcatacat ttcaaaggac atgtctgctg gaagtatata gaggttattg
     1741 attactttat agacagcctc tttaggtgga agattgttta tcaacacgtc agtcacagta
     1801 ttttcgtaaa caatcggttc accttctccg cctccttctt cgttagtgaa gttcatatgc
     1861 gttaagttca tcacatcaga agtatttcct tgcatatcca agtcaattat caaggttctt
     1921 tttccttcat taactgctga ttcaaaccct aacatttgcg cgcacgtact tttacctacg
     1981 ccacctttaa aattaccgat tacatatttc ttcgctacca cgttcctacc tcttttcttt
     2041 tagcaatatt catttgatac tattataaca tatttatttt tagttactac caaaaaaaag
     2101 atatatatgt actaccttat aattaataag taaaaggtag tacataaata aggaaaagct
     2161 gaaatatatt gatttatagc tttcctcaaa gtaatgacgt tatttaattt atcgagaagc
     2221 agagaatact cgcgacttta gtcatgtaga cgaatcagat tttcgataaa aaagaagccg
     2281 tccttcttaa gaacgacaac aaatcactag attaattttt tcaactgttc ataaaagttt
     2341 tcatgcgttc cacataacaa tactggaata accttgtttt ctataatctc gtaagctact
     2401 ctatatgttg tgcccgcata tttgaaccca ctagaccaaa tacctgataa atccccagtt
     2461 ttttgttcac ccttatatgg atcaatcgca atttcatcat aaattaaatt caaaaatttt
     2521 tctttcaatg gcttctcttt tagcttttta aatacttaat gacatgtttt gaaggaacga
     2581 tttcataagc caatttctgt tgccaactcc tctttagtca ttactttaga attagtaagt
     2641 gtatcttcag caatatctct aaaggaagaa tgcattttgt tttttctatt cttaaattct
     2701 acaagaatct catctttatc gtagccttct gcaattatat cagacaaaat atcttcgcta
     2761 aaatcataaa attctttttg tggttcaaca aattcataaa gaataccatt ctctaccaac
     2821 tttgcttcaa cttcgactcc attaggaaca ttaaaatctt taggtactgt caacatgatt
     2881 gaattgcctt gttttcttgt ttttgtaatc atttaaatcc ctcatttcta acagtatgta
     2941 attacttagt aaatacatta taccacgaga taatgtattt acaagtaatt actgtgactc
     3001 gtaatgcgtc cttgctgaat aaatttcaac cacgtgttca tcttcatcta ccttataaac
     3061 aacccggtgt tgtctattca atcttctaga atacctacct tcatgtgtag gttttaactt
     3121 ctcaaatgat tgggtaggga gatagggatc ttcctttaaa gtctgaataa ccttctcaaa
     3181 ttgaggtttc aaattagact gtttgatttt ctttaaatca gctttagccg agtttttaat
     3241 catcacagaa tagttattca ttataagtta tcccaatcaa tttcatcaac attagtaaat
     3301 ccactatcat ctttttctcg cttacgaaca acacccaaag tgcctatttg ctcaagtaat
     3361 agcgtttctt tgattgcttt ccaatcatcc aaaccaataa gcaccgcatt attttcactg
     3421 cgctcactaa tgatttcaat ttccgtatga ttctcattta catctttcaa caacttataa
     3481 aaatttttcc gtgctgagct aggatttaag actgtttttg ccatatctac tccccctcta
     3541 atttatatct ccattctaac gtacttaatt aagtacgtaa attcgattgt tttgtttaaa
     3601 ttggagtacc aaaacagcat tgtaaagtgt tatccgtttc ctttataccc gtggtgctag
     3661 ttaatttttt cctagaggaa aatgtctaaa catgttggta aatcaacaaa aaaacgcata
     3721 gagtagtctc aaaactccca agaaatgagg actacatatg cgttcatcaa aatatactga
     3781 acattataca gatactttta taacattcaa ggaaattatg agaactgttt ctaacatata
     3841 ccacaattgt gtaccagata agattaaaaa ccgaagaaat actgatcaac tgaag
//
LOCUS       DAPBAF010000104         3682 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.110, whole genome shotgun sequence.
ACCESSION   DAPBAF010000104 DAPBAF010000000
VERSION     DAPBAF010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3682)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3682)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3682
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.110"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            288..542
                     /locus_tag="RD451_002829"
                     /pseudo
     CDS             288..542
                     /locus_tag="RD451_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002405927.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
     gene            612..1124
                     /locus_tag="RD451_002830"
     CDS             612..1124
                     /locus_tag="RD451_002830"
                     /inference="COORDINATES: protein motif:HMM:NF013677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDT7568009.1"
                     /translation="MTNKNNERYSTELKATAIKKMMPPENRGIRQLSQTLGIPEATLY
                     SWRKKARIQGNTTPGTKKNVEKWSSEDKFLIVMESFSMNQVELAEYCRKKGLFKEQIE
                     AWKKTCLSANEQEENRTRELATELKEEKKQARQLEKELRHKEKALAEAAALLLLRKKA
                     HAIWGDQEEE"
     gene            1121..2158
                     /locus_tag="RD451_002831"
     CDS             1121..2158
                     /locus_tag="RD451_002831"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HDT7568010.1"
                     /translation="MISSSDRKQAVELIQEANRNGARLTYACNELNISVRTYERWTRE
                     GTIAHDQRPLAKRPVPKNKLTDQEREKIIETVSKKEFMNLPPSQIVPKLADCSIYIAS
                     ESSFYRVLREKNMQHHRGRSQVSQKRIPPSHLATKPNEVWTWDITWLKGPIKGLFYRL
                     YLIIDLFSRKMVGWEIWESEEARHAEKLIKQTVLKERIQGQPLVLHSDNGSPMKAATF
                     QVLLEKLGIQSSYSRPRVSNDNPYSEAAFRTLKYRPEYPNNGFKTIDDARKWTKEFVD
                     WYNDSHLHSGIQFVSPAACHEGRHLAILEKRKQVYEDAKKRHPERWSKGVRNWTPHQS
                     VALNPLKETES"
     gene            2318..2494
                     /locus_tag="RD451_002832"
                     /pseudo
     CDS             2318..2494
                     /locus_tag="RD451_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
     gene            2549..3682
                     /locus_tag="RD451_002833"
                     /pseudo
     CDS             2549..3682
                     /locus_tag="RD451_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012655884.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
BASE COUNT         1389 a          560 c          702 g         1031 t
ORIGIN      
        1 ataaattatc taaagagaat taagttttga ttatgtaata agttttggta ctaaaaaaga
       61 cttgatctaa ttagaccaag tcttttgtta gtgttatatt aataacaaaa taaaaataag
      121 aagtcgctca ctccccgacc aaagtttgtg agcaaaataa acagtcgatg tttgtttctt
      181 aattgtatat cttgatatta aacgatttaa gattattctt caagatatat attcgcaaat
      241 gtaattggaa aagcgacttc ttaaacaaaa ttaaggagtc gctttttatg gcaaaaataa
      301 cgaaaaatga gcaagaaaat ttggtggaaa attacacaaa aaaaccggcg tactctaata
      361 gccggttaga cgcacatttc gtgtgcactt ctaatccgaa attgagcttt gacgctatga
      421 cgatagtcgg aaaccttaat aaaaacagcg ctaaaaagct atccgatttt atgagtttag
      481 atccacaaat tagactttgg gatatacttc aaacaaaatt taaagctaaa gcactacaag
      541 accccctatg ttaggctagt tgtcgtatag gataataagt tataataaag actatacgga
      601 ggatgattac catgacaaat aaaaacaatg aacgttactc taccgaactg aaagcgacag
      661 ccatcaagaa aatgatgcca cccgaaaata gggggattcg ccaattaagt caaactttgg
      721 gcattccaga agcgactctt tattcttggc gtaaaaaagc tagaattcaa gggaatacta
      781 cacccggaac gaaaaaaaat gtcgaaaaat ggtcaagtga agataaattt ttaattgtga
      841 tggaatcatt ctcaatgaac caagtagaac ttgcggaata ttgccgaaag aagggcttat
      901 ttaaagaaca aattgaggct tggaagaaaa cgtgcttatc tgcgaatgaa caggaagaaa
      961 atcgaacgag agaacttgca actgaactaa aagaagagaa aaaacaagcg cgtcaattag
     1021 agaaagaatt acgtcataag gaaaaagcat tagcggaagc cgctgctctc ttattactaa
     1081 gaaaaaaagc acacgcgatt tggggggacc aagaggaaga atgatttcat cttcagatcg
     1141 caaacaagct gttgaactta ttcaagaagc caatcgcaat ggggcccgtc tcacctatgc
     1201 ctgtaatgag ctgaatatta gcgttcgaac ctacgaacga tggacgcgtg aaggtacgat
     1261 agcgcatgat caacgccctt tggcgaaacg tcctgtaccc aaaaataaac tgacggatca
     1321 agaacgcgaa aaaataatag aaaccgtttc aaaaaaagaa tttatgaatt tgccacctag
     1381 ccaaattgta ccaaaacttg cggattgctc gatttatatt gcatcagagt ctagcttcta
     1441 tcgtgtattg cgagaaaaaa atatgcaaca tcaccgtggc cgaagtcaag tttcacaaaa
     1501 acgcataccg ccaagtcacc ttgcgacgaa gccaaatgaa gtttggactt gggatattac
     1561 ttggctaaaa ggtccaataa aaggactctt ttaccggtta tatctcatca ttgatttatt
     1621 tagccgtaaa atggtaggct gggagatttg ggaatcagaa gaagctcgtc atgccgaaaa
     1681 acttattaaa cagacggtgc ttaaggaacg tatccaagga cagccgttgg ttttacactc
     1741 cgataatggc agccctatga aagccgcgac ttttcaagtc ttactcgaaa aattaggaat
     1801 tcaaagttct tattcaagac cacgagtgag taatgacaat ccttattcgg aagcggcttt
     1861 ccgaacgtta aaatatcgac cagaatatcc caataacggc tttaaaacaa tagatgatgc
     1921 tcgaaaatgg acgaaagagt ttgtcgattg gtataacgat tctcatttgc atagtgggat
     1981 tcaatttgtg tctcctgcag cgtgtcatga aggacgacat ctcgctattt tagagaaacg
     2041 aaagcaggtt tacgaggacg ctaaaaagcg ccatcctgaa cgctggtcaa aaggtgttcg
     2101 aaattggact ccacatcaat cggtggcgtt gaatccttta aaagaaacag aaagttaaca
     2161 ggagcataat ctttcaagat tatcaaataa ccctcgtcac ccaatagggg aaaaagttat
     2221 tcttccccta ttggataacg aggccaaccg accataggga ggttctgctt tttgataggt
     2281 ggaaaataaa aatacgacaa ctatattgac aaacaccgac catcgtccag taaagagacg
     2341 caataaattc tatcgaagtt tacgcactgc ctctacaacg attaaaggca tggaagccat
     2401 ccgaggatta tataagaaaa cccgaaaaga aggcactctc ttcgggtttt cggtctgtac
     2461 tgaaatcaag gtattattgg gaatcccagc ttaaatcata gataccgtaa gggattttat
     2521 tctttattta aaactttgca acagaaccga atcattaaaa aaacattata cagagccttg
     2581 ggaagatgaa gtttttagag taattattga atataacaat gttcctattg gatatggaca
     2641 aatatataaa atgtatgatg agttatatac tgattatcat tatccaaaaa ctgatgagat
     2701 agtctatggt atggatcaat ttataggaga gccaaattat tggagtaaag gaattggtac
     2761 aagatatatt aaattgattt ttgaattttt gaaaaaagaa agaaatgcta atgcagttat
     2821 tttagaccct cataaaaata atccaagagc aataagggca taccaaaaat ctggttttag
     2881 aattattgaa gatttgccag aacatgaatt acacgagggc aaaaaagaag attgttattt
     2941 aatggaatat agatatgatg ataatgccac aaatgttaag gcaatgaaat atttaattga
     3001 gcattacttt gataatttca aagtagatag tattgaaata atcggtagtg gttatgatag
     3061 tgtggcatat ttagttaata atgaatacat ttttaaaaca aaatttagta ctaataagaa
     3121 aaaaggttat gcaaaagaaa aagcaatata taatttttta aatacaaatt tagaaactaa
     3181 tgtaaaaatt cctaatattg aatattcgta tattagtgat gaattatcta tactaggtta
     3241 taaagaaatt aaaggaactt ttttaacacc agaaatttat tctactatgt cagaagaaga
     3301 acaaaatttg ttaaaacgag atattgccag ttttttaaga caaatgcacg gtttagatta
     3361 tacagatatt agtgaatgta ctattgataa taaacaaaat gtattagaag agtatatatt
     3421 gttgcgtgaa actatttata atgatttaac tgatatagaa aaagattata tagaaagttt
     3481 tatggaaaga ctaaatgcaa caacagtttt tgagggtaaa aagtgtttat gccataatga
     3541 ttttagttgt aatcatctat tgttagatgg caataataga ttaactggaa taattgattt
     3601 tggagattct ggaattatag atgaatattg tgattttata tacttacttg aagatagtga
     3661 agaagaaata ggaacaaatt tt
//
LOCUS       DAPBAF010000105         3430 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.111, whole genome shotgun sequence.
ACCESSION   DAPBAF010000105 DAPBAF010000000
VERSION     DAPBAF010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3430
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.111"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            <1..411
                     /locus_tag="RD451_002834"
     CDS             <1..411
                     /locus_tag="RD451_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7568011.1"
                     /translation="GLYYSPVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAP
                     QEYLSRAYNDAPKYCANIVDTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLT
                     ELKGYHVTTGEPVCQPRRPNSRIDKVRYMFNKIT"
     gene            521..571
                     /locus_tag="RD451_002835"
                     /pseudo
     CDS             521..571
                     /locus_tag="RD451_002835"
                     /inference="COORDINATES: protein motif:HMM:NF019662.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance efflux system leader
                     peptide"
     gene            605..1981
                     /gene="tet(L)"
                     /locus_tag="RD451_002836"
     CDS             605..1981
                     /gene="tet(L)"
                     /locus_tag="RD451_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001574277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(L)"
                     /protein_id="HDT7568012.1"
                     /translation="MNTSYSQSNLRHNQILIWLCILSFFSVLNEMVLNVSLPDIANDF
                     NKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSF
                     FSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGG
                     MIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFT
                     TSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFV
                     SMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLS
                     VSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFT
                     SFLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNV
                     YKHSQRDF"
     gene            2576..2887
                     /locus_tag="RD451_002837"
                     /pseudo
     CDS             2576..2887
                     /locus_tag="RD451_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000277654.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
     gene            3022..>3430
                     /locus_tag="RD451_002838"
     CDS             3022..>3430
                     /locus_tag="RD451_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000143686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type A chloramphenicol O-acetyltransferase"
                     /protein_id="HDT7568013.1"
                     /translation="MTFNIINLETWDRKEYFNHYFNQQTTYSVTKEFDITLLKSMIKN
                     KGYELYPALIYTIVNIINQNKVFRTGINSEGNLGYWEKLNPLYTVFNKETEKFSNIWT
                     ESNVSFNSFYNSYKSDLLEYKDKNEMFPKKPIPE"
BASE COUNT         1139 a          470 c          641 g         1180 t
ORIGIN      
        1 ggcttatact atagccctgt tagtacccca gcagattttc ggatgcttgc tcctattgta
       61 ttggaacaag tcttaaaaaa agctggaaca gaattgttag agccatatct tagttttaaa
      121 atttatgcgc cacaggaata tctttcacga gcatacaacg atgctcctaa atattgtgcg
      181 aacatcgtag acactcaatt gaaaaataat gaggtcattc ttagtggaga aatccctgct
      241 cggtgtattc aagaatatcg tagtgattta actttcttta caaatggacg tagtgtttgt
      301 ttaacagagt taaaagggta ccatgttact accggtgaac ctgtttgcca gccccgtcgt
      361 ccaaatagtc ggatagataa agtacgatat atgttcaata aaataactta gtgtatttta
      421 tgttgttata taaatatggt ttcttgttaa ataagatgaa atatttttta ataaagattt
      481 gaattaaagt gtaaaggagg aattaattat gaagtgaaat gaatgtaaca gggttcaatt
      541 aaaagaggga agcgtatcat taaccctata aactacgtct gccctcatta ttggagggtg
      601 aaatgtgaat acatcctatt cacaatcgaa tttacgacac aaccaaattt taatttggct
      661 ttgcatttta tcttttttta gcgtattaaa tgaaatggtt ttgaacgtct cattacctga
      721 tattgcaaat gattttaata aaccacctgc gagtacaaac tgggtgaaca cagcctttat
      781 gttaaccttt tccattggaa cagctgtata tggaaagcta tctgatcaat taggcatcaa
      841 aaggttactc ctatttggaa ttataataaa ttgtttcggg tcggtaattg ggtttgttgg
      901 ccattctttc ttttccttac ttattatggc tcgttttatt caaggggctg gtgcagctgc
      961 atttccagca ctcgtaatgg ttgtagttgc gcgctatatt ccaaaggaaa ataggggtaa
     1021 agcatttggt cttattggat cgatagtagc catgggagaa ggagtcggtc cagcgattgg
     1081 tggaatgata gcccattata ttcattggtc ctatcttcta ctcattccta tgataacaat
     1141 tatcactgtt ccgtttctta tgaaattatt aaagaaagaa gtaaggataa aaggtcattt
     1201 tgatatcaaa ggaattatac taatgtctgt aggcattgta ttttttatgt tgtttacaac
     1261 atcatatagc atttcttttc ttatcgttag cgtgctgtca ttcctgatat ttgtaaaaca
     1321 tatcaggaaa gtaacagatc cttttgttga tcccggatta gggaaaaata taccttttat
     1381 gattggagtt ctttgtgggg gaattatatt tggaacagta gcagggtttg tctctatggt
     1441 tccttatatg atgaaagatg ttcaccagct aagtactgcc gaaatcggaa gtgtaattat
     1501 tttccctgga acaatgagtg tcattatttt cggctacatt ggtgggatac ttgttgatag
     1561 aagaggtcct ttatacgtgt taaacatcgg agttacattt ctttctgtta gctttttaac
     1621 tgcttccttt cttttagaaa caacatcatg gttcatgaca attataatcg tatttgtttt
     1681 aggtgggctt tcgttcacca aaacagttat atcaacaatt gtttcaagta gcttgaaaca
     1741 gcaggaagct ggtgctggaa tgagtttgct taactttacc agctttttat cagagggaac
     1801 aggtattgca attgtaggtg gtttattatc cataccctta cttgatcaaa ggttgttacc
     1861 tatggaagtt gatcagtcaa cttatctgta tagtaatttg ttattacttt tttcaggaat
     1921 cattgtcatt agttggctgg ttaccttgaa tgtatataaa cattctcaaa gggatttcta
     1981 aatcgttaag ggatcaactt tgggagagag ttcaaaattg atcctttttt tataacagga
     2041 attcaaatct ttttgttcca ttaaagggcg cgattgctga ataaaagata cgagagacct
     2101 ctcttgtatc ttttttattt tgagtggttt tgtccgttac actagaaaac cgaaagacaa
     2161 taaaaatttt attcttgctg agtctggctt tcggtaagct agacaaaacg gacaaaataa
     2221 aaattggcaa gggtttaaag gtggagattt tttgagtgat cttctcaaaa aatactacct
     2281 gtcccttgct gatttttaaa cgagcacgag agcaaaaccc ccctttgctg aggtggcaga
     2341 gggcaggttt ttttgtttct tttttctcgt aaaaaaaaga aaggtcttaa aggttttatg
     2401 gttttggtcg gcactgccga cagcctcgca gagcccacct ttacgaagta aagtatagtg
     2461 tgttatactt tacatggaag ttgtaccgaa atattgtgtt gtgaagtcta tataatttta
     2521 aaattatgaa gtctatatac gtgcgtaaag atatttaaag agattaaaaa taataaaaat
     2581 aaaaattgaa ttaaaaagag atatggttga ttattggaac gattgtttta atgatttaca
     2641 tatattacaa ccagattgga aaactatcga acgtacttct gatagagcaa tggtttttat
     2701 gttgttgaat gatgaagaag aatggggaaa attagaaaga cgtactaaga ataaatataa
     2761 aaaattaatt aaagaaatat ctctaattga tttaactgat ttaatgaaat cgactttaaa
     2821 agcgaacgaa aaacaattgc aaaagcagat tgatttttgg caacgtgaat ttagattttg
     2881 gaagtaaagt aactttgttt tatacaaaat gttactttag tataattaac gtttaagagg
     2941 tgacacaata tatgaaaaaa tcagaggatt attcctccta aatacaaaga gataagatga
     3001 aatttaggag gaaaattata tatgactttt aatattatta atttggaaac ttgggataga
     3061 aaagaatatt ttaatcatta tttcaatcaa caaacaactt acagtgttac taaagaattt
     3121 gatatcactt tacttaaaag tatgataaaa aataaaggat atgaactgta tcctgctttg
     3181 atttatacaa ttgtaaatat tataaatcaa aataaagtat ttagaacagg aattaatagt
     3241 gagggaaatt tgggttattg ggaaaaatta aaccctttat atacagtctt taataaagaa
     3301 actgaaaaat tttctaacat ttggacagaa tcaaatgtta gttttaattc tttttataat
     3361 agttataaga gtgacttact tgaatataaa gataaaaatg aaatgtttcc taaaaaacca
     3421 atacctgaaa
//
LOCUS       DAPBAF010000106         3282 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.112, whole genome shotgun sequence.
ACCESSION   DAPBAF010000106 DAPBAF010000000
VERSION     DAPBAF010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3282)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3282)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3282
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.112"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            2..586
                     /locus_tag="RD451_002839"
     CDS             2..586
                     /locus_tag="RD451_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDT7568014.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
     gene            complement(663..1856)
                     /locus_tag="RD451_002840"
     CDS             complement(663..1856)
                     /locus_tag="RD451_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDT7568015.1"
                     /translation="MTGGLKMIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADM
                     DFLSPGGVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVL
                     TSLAAAVQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDME
                     KKIEENNVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHT
                     FTSMLTIDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEI
                     NTFGLIGTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLD
                     FTAYISDDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYA
                     LETID"
     gene            1920..2300
                     /locus_tag="RD451_002841"
     CDS             1920..2300
                     /locus_tag="RD451_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HDT7568016.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            2374..2736
                     /locus_tag="RD451_002842"
     CDS             2374..2736
                     /locus_tag="RD451_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7568017.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
BASE COUNT         1114 a          538 c          622 g         1008 t
ORIGIN      
        1 tatggcattc ccacaactag atttaaaaag tgaaaaagga ccaaaagctg ttatcaaaac
       61 aaaccgtggt gacattactg ttcaattatt ccctgaacta gcaccgaaga cggttcaaaa
      121 tttcattgaa ctttccaaaa aaggttatta tgatggcgtg atttttcacc gcgttattcc
      181 tgatttcatg atccaaggcg gcgatccaac tggaacagga atgggtggcg aaagtattta
      241 tggcgaaagt tttgaagatg aattcagtcg tgaactgttc aaccttcgcg gagctttatc
      301 tatggcaaat tcaggtccaa acacaaacgg aagccaattc tttattgtaa ataacacaaa
      361 tgtgccagct aatatgcttg gacaactaga aggtgctgga ttcccatcag aaatcattga
      421 agcgtataaa ggtggcggaa ctccttggct agatttccga catacagtct ttggacatgt
      481 actagaaggg atggacacag tagatgaaat cgcaaatgta caacgtggtc cacaagaccg
      541 acctgtacat gatgtagtga ttgaaacaat tgaaatttca gaatagtttg gtatggtacg
      601 gagtaattat gaaaaaggac gaaacctagt aaggtctcgt ccttttattt tgaataaatg
      661 atttaatcga ttgtctctaa agcatacttg attcgattaa gtccttccag taaagtttct
      721 tctggacaag caatattcaa gcgcatatgc ccatgaccgg aaggaccaaa cgtgatgcca
      781 ggatttaata cgacttttcc tttccgaaca agagtgttct ccaattcttg gtcgtctgaa
      841 atataggcgg taaaatctaa ccacattaag taagttcctt cagggttcat tattctcact
      901 ttcggaagat actgttcaaa aaactgatta actgtttgaa catttttttc tagataagga
      961 atcagttggc ttaaccattc tccacccgtc tcataagccg cttgggttcc aatcagtcca
     1021 aaagtgttga tttcgtgctg ttggttcatc actaaatgtt tttcaaaatc agctttcatc
     1081 tctggatttt tgataaatac cattgaattt ttgattgcag ctagattgaa agtcttggtt
     1141 gcggaagtaa aagcaactag tagatcatct aaattaggat caatcgttag catggaagta
     1201 aatgtatgat cgaataaagt taaatcttga tggatctcgt cactaaacag aatcacttga
     1261 tgttttaaac acaattcgct taactgtttc aattcttctt tgctccaaac acgccctcca
     1321 ggattgtgag gattgcataa aatcattgct tttacattgt tttcttcgat ttttttctcc
     1381 atgtcagaca agtccatgat gaaatgatta tttttttcta gcaaagagct tcgaacgatg
     1441 tgacgttgat ttgtttctat aatagaggaa aatggaggat aaactgggtc atgaatcaaa
     1501 atagaatcgc ctggttttgt aaaagtttgt actgctgcag ctaaactggt taacacacca
     1561 cttgtaaaaa cgatattttc tttcgtcaac tccacagcat ggtgttggcg ttcccaatga
     1621 atgatagcct gatatagttt atcagacaga gtggcataac caaagattcc atgtttgatg
     1681 tattcactaa acgctttagc taccccaccg ggagacaaga agtccatatc tgctacccac
     1741 aaaggaagta agtcatccat ttgatatgtc tcagcaattg cgtcccattt tacactttct
     1801 gtatcttttc ttgaaatctg tttatcaaat tcgatcatct taagacctcc agtcattttc
     1861 gtcgcttctt tttttgagct atttacagta taatgataaa tgcgaagaga gggaagtaga
     1921 tgacttataa aattggacaa ataattgaag gaaaagtgac agggatacag ccttatggcg
     1981 cattcgtttc tcttgataac gagacgcaag gacttattca tgtttcagaa gtacaatccg
     2041 gttatacgaa aaatatccat tcattgttaa aagtcggaca gccagtaaca gttcagatca
     2101 tcgacattga tgaatattcc aaaaaaatca gtttatcttt aagaacgtta gaaaaaacaa
     2161 atccagctgt tccatatcgc agaaaaaggt atttcacgaa taaaaatcgt aagatcggat
     2221 ttaccactat tgcggagcag ttacctattt ggatagaaga agcattatct gaactagaac
     2281 ggaaagaaaa taagaaataa aaagtgtatt ttttctgaaa atgtgctaga atttttatgt
     2341 aagccataga acaagttgat cgaggtggaa attttggcaa gcaaaagagt tgctggtaca
     2401 attatgttgc atttggagga tggtactaaa aaatttttgg tccattcaat tgatgacaag
     2461 ttggaatttg cgttagcgga actttctgaa ggaaagactg gtttagcgaa tatacttaat
     2521 ttcttaaaag aaatagttca tatcgatgtt agcaagatta gtttgatgga attgacaaat
     2581 acacatatta aagaggaaaa tgttccgttg tttgtctttg aaactgaaca aaagaatcaa
     2641 agagaagaat taggcgaagg atatatttgg gaagaaccag gtcaaatgcg ctctgttctt
     2701 ggaacttacg aagtagaggg agtgcctttc ttctaaaata cagattaagc gaacaaagaa
     2761 gtttgaattt ttttcaaact tcttttttta ttgtttggtc caaaaaatac aatgaaatgt
     2821 tctgctaaag atagtttttt agtgcatttt attttcaaaa tatgttgaaa acggttgtat
     2881 aacgaataat aataattgat cgaaaaatca tttcacaaag taatgcttaa tttatagttg
     2941 accaaggaag aaatacatga taaatttaac agcgttgatt ctgaagtgga tgttatatca
     3001 catttctaaa aaatttaaaa aatagttatt gacatgttac taacgacatg ataagataac
     3061 tgagtcgtta aaaaagaacc acttgcgaag cttgattcta tcgaaaaaaa cttcaaaaaa
     3121 gttcttgaca aataacaaac gataagttat gataaatgag ttgctgaaag atttcgaaaa
     3181 acgaaatcga aaaaaacttt taaaaaagag ttgacaatcg cttgtctctc tgatatgata
     3241 taaaagttgc tacggcagcc aaaaacgaat cgggaaacac tc
//
LOCUS       DAPBAF010000107         3211 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.113, whole genome shotgun sequence.
ACCESSION   DAPBAF010000107 DAPBAF010000000
VERSION     DAPBAF010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3211)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3211)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3211
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.113"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            <1..821
                     /locus_tag="RD451_002843"
     CDS             <1..821
                     /locus_tag="RD451_002843"
                     /inference="COORDINATES: protein motif:HMM:NF013235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HDT7568018.1"
                     /translation="TMVDSNGKPILNKYGKPKKVVKMPIDNSVTLSIQRLRHLASLGN
                     ESNKQIVDRYFSNQPEPLTINEQMELLQTGINLHSIYMVDENENEIITAPAIARWVIN
                     KHTLEVTARINPEYLEWFSEVVNQYILFNLRDFVKLKSKYSMILFLELSTFWNTGMYY
                     KRINDLREILGVNPTRNNRDFINNVLKPAIAALKEYFPELSLTVEKNSSDSRKITHVR
                     LKFDKLTITDMQERLRSSEGASLVEYQQELENMEGEEKAVNDPTPEIDLSNVEW"
     gene            935..1303
                     /locus_tag="RD451_002844"
     CDS             935..1303
                     /locus_tag="RD451_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7568019.1"
                     /translation="MENTNQTPNTAPTNQTSPAERKADLIRLYSRLEGMKLQHVPTAP
                     KAPDGFPKSAESLEFFECKVCGSTFQTILRESVASGCPKCEHDRLGILADHLPEPDKN
                     SCLNNRKKPVTVMAMGFLCI"
     gene            1477..1785
                     /locus_tag="RD451_002845"
     CDS             1477..1785
                     /locus_tag="RD451_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7568020.1"
                     /translation="MKEMKMKQVIYPVIIGVLAIALIILGVNCYNLSKENNQLETKNN
                     KQEIQIAKQAYVISDYKTYFRENYVDTVKYRSHFTDKQILNVYREALRDGKISDEGAN
                     "
     gene            2048..2368
                     /locus_tag="RD451_002846"
     CDS             2048..2368
                     /locus_tag="RD451_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7568021.1"
                     /translation="MERFLTKNRKGGGKLEKKEDLLNAFKNLDEKDQLKALLRLHDIT
                     YSDIAERLTVKKGEREGQKGVSLVTVQKAFQSKTNLESDRWKEIVKVATKLIEERQND
                     QNKA"
     gene            2499..2708
                     /locus_tag="RD451_002847"
     CDS             2499..2708
                     /locus_tag="RD451_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7568022.1"
                     /translation="MIRKLNNIKLSLAILTLFFGIYNNSRMALFFLTLLIFMNLIIHN
                     FKELENTAPAPSQGNQESEGMPHAW"
     gene            2698..2970
                     /locus_tag="RD451_002848"
     CDS             2698..2970
                     /locus_tag="RD451_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7568023.1"
                     /translation="MLGSFKKDKEVKTRGALTPSQQNKLGTKATFHPVRDQANQKELI
                     GVCVGFTSEKFFPIIECKIHGITTREVARKVVKWHTSQTKTNHKKR"
     gene            3018..>3211
                     /locus_tag="RD451_002849"
     CDS             3018..>3211
                     /locus_tag="RD451_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7568024.1"
                     /translation="MNNKNTKNTNTNHEKRSFFDKLFKKKKNGKVSILKMIGWIFLAF
                     FIVAVNSSGGDKKEAASKDTT"
BASE COUNT         1212 a          577 c          647 g          775 t
ORIGIN      
        1 taactatggt agatagtaac ggcaagccta tcttaaacaa atatggaaag ccgaaaaagg
       61 tagtaaaaat gccgatagat aactcggtta ctttgagtat tcagcgccta cggcacctag
      121 caagcttagg aaacgaaagc aacaaacaaa tagttgatcg ttacttttca aaccagccag
      181 aacctctgac aattaacgag caaatggaat tactccaaac ggggataaat ttacactcta
      241 tttatatggt agatgaaaat gaaaatgaga tcataaccgc gcccgctata gcaaggtggg
      301 taataaataa gcatacgcta gaagtaacag cgcggatcaa tccagaatat ttagagtggt
      361 tttcagaagt ggttaaccaa tacattttat ttaatctaag agactttgtg aagttaaaaa
      421 gtaagtactc catgatcctt ttcttagagc tttctacctt ttggaataca ggaatgtatt
      481 ataaaaggat taatgattta agagaaattt taggagtcaa tccaacgaga aataacagag
      541 attttataaa caacgttcta aagcctgcta tcgctgctct caaagagtac tttccagagc
      601 taagcctaac agtggaaaag aattctagcg actccagaaa gatcactcat gtaagattga
      661 agtttgataa gctaacaata accgatatgc aagaacgcct aagaagcagc gagggagctt
      721 ctttagtaga gtaccaacaa gagttggaaa atatggaagg agaggaaaaa gctgtcaacg
      781 atccaactcc agagatcgac ctttccaacg tggaatggta acacctgtca gcaatctaat
      841 ccaataaacc aaagtacttg taaggcgcga gggctccttt tagagccttc tagtcctata
      901 ccaaaccaag caaaataaag gagctataac caacatggaa aacactaacc aaacaccaaa
      961 tacagcacca actaaccaaa ctagcccagc cgaacgcaaa gccgatctta ttagattgta
     1021 ctcacgcctt gaaggtatga aactccaaca cgttccgacc gctccaaagg cgccagacgg
     1081 cttcccaaaa tcggcagaga gccttgagtt tttcgagtgt aaggtgtgcg gatcgacttt
     1141 tcaaacgatt ttaagggaat ccgttgcgag tggctgcccc aaatgtgaac atgatcgctt
     1201 aggaatttta gccgatcatt taccagaacc agacaaaaac agttgtttaa ataatcgaaa
     1261 aaaacctgta accgttatgg ctatggggtt tttgtgtatt tgagataatt tccaagggtt
     1321 atttatggat ttattttaaa aaatctatta aattatacta ccactggtag taatataaat
     1381 atatcgaaag ggtacgaggg ttaaagcgta atggcggaat gagtaccgtt ctcttttgaa
     1441 aataccaaac caaccaatta aaggagagaa agtaatatga aagaaatgaa aatgaagcaa
     1501 gtaatttatc ccgtgattat tggagtttta gctatcgctc ttattatcct tggtgtaaat
     1561 tgctataact taagcaagga aaataatcaa cttgagacca aaaacaacaa gcaagaaatc
     1621 caaatagcca agcaagctta cgttatcagc gattacaaga cttattttcg tgaaaactat
     1681 gtagacaccg tgaaatatcg ctcccacttc actgataaac aaattttaaa tgtttatcga
     1741 gaagctctta gagatggaaa aatcagcgat gagggagcta actagtggaa gagctcattt
     1801 tgctggctat gttattacag gaaaagaagc gtgaacgaga agcctaacag ctggaaagaa
     1861 tccgaatagg atatgaggaa gcagatcggg aaagagatca gaaaatagag gagctggaga
     1921 agcgtatcca agaactttcc aaaaactatg ataataacca agattgggaa caagagtggc
     1981 ggaaaatcgt tggtataaag gaaaatgaat acttagtgag aaagccgcca gaagaagagg
     2041 aagacccttg gagcgatttc taactaaaaa tcggaaggga ggtggtaagt tggagaaaaa
     2101 ggaagattta ttgaacgctt ttaagaacct agacgagaaa gatcaactta aagcgttatt
     2161 aaggcttcat gatataacat acagcgatat tgctgaaaga ttaaccgtta aaaaaggcga
     2221 gagggaagga caaaaaggtg ttagcctcgt gactgtacaa aaagctttcc aatcaaagac
     2281 caacttggag agtgatcgct ggaaagagat tgtaaaagtc gctaccaagc taattgaaga
     2341 gcgacaaaac gaccagaaca aagcataaaa aaagcccgtc catttaccgc tgaccaaagc
     2401 aataaaatga acgagccaca ccatttactt ttaggggtaa ccacacgccc taaaagctac
     2461 caaaccattt accaaataac cactaaggag atttagaaat gattagaaaa cttaataata
     2521 tcaagctttc tttggcaatt ttaacactat tttttggaat ttacaataat tccagaatgg
     2581 ctttgttttt tcttacgtta ttgatattca tgaacttaat tatccataat ttcaaggagt
     2641 tagaaaatac agctccagcg ccctctcaag gaaaccaaga aagtgagggc atgccacatg
     2701 cttggtagtt ttaaaaagga taaggaagta aaaacacgag gagcccttac accaagccag
     2761 caaaataagc ttggtacaaa agccactttc caccccgtcc gagatcaagc caaccaaaaa
     2821 gaactaattg gcgtttgtgt agggtttact tcagagaaat tttttccaat aatagagtgc
     2881 aaaatacacg ggatcacaac tagagaagtt gctagaaaag ttgtgaaatg gcacaccagc
     2941 caaaccaaaa ccaaccataa gaaacgttaa aaacgttcct aagagcgttt gaaaattaaa
     3001 ttaagggaga tttaagaatg aacaacaaaa acaccaaaaa taccaatact aaccacgaga
     3061 agagaagctt ctttgataag cttttcaaaa agaagaagaa tggaaaagta tctattttga
     3121 aaatgatcgg ctggatattt ttagcctttt tcatagttgc tgtgaacagt agcggcggtg
     3181 ataagaaaga ggctgcttca aaagatacca c
//
LOCUS       DAPBAF010000108         3045 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.115, whole genome shotgun sequence.
ACCESSION   DAPBAF010000108 DAPBAF010000000
VERSION     DAPBAF010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3045)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3045)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3045
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.115"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            284..2110
                     /gene="ltrA"
                     /locus_tag="RD451_002850"
     CDS             284..2110
                     /gene="ltrA"
                     /locus_tag="RD451_002850"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HDT7568025.1"
                     /translation="MLKKNKLRYNEYYDMQHIYDELYAQSKNGNNFYKLLEIIGSEQN
                     ICLAYRNLKSNSGSKTAGTDGMTIDDIKQLSNAEIVATVRESLSNYRPKSVRRVFIPK
                     AGSDKMRPLGIPCIWDRLVQQCILQVLEPICEPKFHNHSYGFRANRSAHHAVSRVTTL
                     INLSKYHYCVDVDIKGFFDNVNHGKLLKQIWTLGIRDKRLICIISKMLKAEIDGEGVP
                     EKGTPQGGLLSPLLSLIVLNELDWWVSSQWETFQPKNRSKNGWLQYAKKYTKLKSGFI
                     VRYADDFKIMCSTYGEAQRFYHSTVDFLNKRLKLEISPEKSKVVNLKKNSSDFLGFKI
                     KVIPKGRTKHGYVAKTDMNQKALKKAKTNLKLKVKDIARHTTGFNISRYNLTVIGMQN
                     YYCIATNVYNNLTEVSYALLPTIRIRLRNIAKSVPFESTSSEFQSRTKGIRPKTKIVM
                     IADNPLLPIQGVQHKNPMNFSQDICNFTKQGRNKVHEDVVVVTKEEIRALLENENPAD
                     SVEFNDNRISAYIAQQGNCYVMNRRGTPSTLICIHKSDKGDNLDRYSNLAFVEIPIAK
                     AILTESADEAKSLLKGYVLNSQQKKKLNRIRTNYGYQTITGK"
     gene            2244..>3045
                     /locus_tag="RD451_002851"
     CDS             2244..>3045
                     /locus_tag="RD451_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDT7568026.1"
                     /translation="MPEIADEISILNLTSKSENQGLLDPYVIMKKKKDSESLAIDILT
                     FLTGISSRDGEKFPVLRKAIRTVTQSDQRGLLQVINELRKDGSPIAENIADHIESFTD
                     YDFAHLLFSDGSITQSISLDKQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVIS
                     TFALDFIHSNREIFKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDD
                     LLDERLKNNIGLKFAFRSTDIHEIKKTLEFFGLDQEDQSNQKRLRDLEN"
BASE COUNT         1064 a          529 c          663 g          789 t
ORIGIN      
        1 ggatatatgt acagatagtg tgtttggaac gttgaaagct gacaacatgg agattttact
       61 gtctgtgaag tgttcacatc agaaagttat tgtgagatta gcaatgatat aaggtgtgtt
      121 aatgtcagtg agagtggtgg cacagtacct atgaaaccgt gataacaagc ggtggaggga
      181 tagccactag tcatatgaag aatagaatta ctaagaaaaa tggtatgggt tcgagtaaga
      241 ctaagagatg tacttgctcc tgcaaacaag gagggtacag accatgctaa agaaaaacaa
      301 gctccgctat aacgagtatt atgatatgca acatatttat gacgagttat acgcacagag
      361 caagaacggt aataactttt ataagttact tgaaattatt ggttcggaac aaaatatttg
      421 tttagcttac cgtaatctga aatcaaacag tggcagtaaa acggctggaa cggatggaat
      481 gacgatagac gatataaaac aactcagcaa tgctgagatt gttgctaccg ttcgggaaag
      541 ccttagcaac taccgcccca aatcagtcag acgtgttttc attccaaaag ctgggagcga
      601 taaaatgcgt ccattgggga ttccgtgtat ctgggacagg ctggtacaac aatgtatcct
      661 gcaagtccta gagccgatat gcgaaccaaa gttccataat cattcctatg gattccgtgc
      721 gaatcgaagt gcccaccatg cagtcagcag agtaacgaca ctgataaatt tatcaaaata
      781 tcattactgt gttgacgtag acattaaagg atttttcgat aatgtcaatc atggaaaact
      841 attaaaacaa atctggacac ttggtattcg ggataaaaga ttgatttgca ttatcagcaa
      901 aatgctgaaa gccgaaattg acggcgaggg tgtcccagaa aaaggaacgc cacaaggcgg
      961 tctgttaagt ccactgctct ccctcatagt ccttaatgaa ttagactggt gggtaagcag
     1021 tcagtgggaa acattccagc cgaagaaccg cagtaaaaat gggtggcttc aatacgcaaa
     1081 gaaatatacc aaactgaaaa gcggttttat tgtacgttac gctgatgatt ttaaaatcat
     1141 gtgttcaacc tatggagaag cacaaagatt ttaccacagt accgtagatt ttcttaataa
     1201 aaggctgaaa ttagaaatca gtccagagaa atcaaaggta gtaaatctga agaaaaattc
     1261 atcagatttt ctggggttca aaatcaaagt cattccaaaa ggaagaacga aacacggtta
     1321 tgttgccaaa acagatatga accaaaaagc attaaagaaa gcgaaaacaa atctaaagtt
     1381 aaaggtaaaa gatatagcca gacatacgac tggcttcaat atcagcagat ataatctgac
     1441 agttatcggt atgcagaatt actactgcat agcaactaac gtatataaca acctgacaga
     1501 agtaagttac gctctcttac cgaccatacg aatccgttta aggaacattg caaaatcagt
     1561 tccatttgaa agtacaagtt cagaatttca gagcaggaca aaaggaatca gaccaaaaac
     1621 aaaaatagtg atgattgcgg ataatccgct attgccgatt caaggagtac aacacaaaaa
     1681 tcctatgaat ttctcgcaag atatttgtaa ttttacaaag caagggagaa acaaggtgca
     1741 tgaggacgtt gtagttgtaa caaaagaaga aatccgagcg ttgttggaaa atgaaaaccc
     1801 tgccgatagc gtagagttta acgacaatcg tatttcggca tatatcgcac aacaaggcaa
     1861 ctgctatgta atgaatcgtc gaggaactcc gtccactctg atatgtattc acaaatcaga
     1921 caaaggagat aaccttgaca gatattctaa tctggcattt gtggaaattc ccattgcaaa
     1981 ggcaatccta acagaatcag cagacgaagc aaaatcactg ttaaaaggtt atgttcttaa
     2041 tagtcagcag aagaaaaaac tgaacagaat acggacgaat tacggatacc agacaataac
     2101 tgggaaataa cttataaatc tatttggata tgatggaacg ccgtatgaag cgaaagtttc
     2161 atgtacggtg tgaagcgggg gaaaacttgg agataacatc aaaaagttac ctatcgctat
     2221 agcgaggagg gtggaaagaa accttgccag aaattgcgga tgaaatcagt atcctcaact
     2281 tgacgagtaa gtcagaaaat caaggtctgc ttgatcctta tgtgattatg aagaaaaaga
     2341 aagactcgga aagtttagca attgatattc tgactttttt aacaggaatt tcaagtcgag
     2401 acggggagaa gtttcctgtg ttacgtaaag ccattcgaac ggtgactcaa agtgatcaac
     2461 gggggttatt acaagttatt aacgaattgc gaaaagacgg gtcaccaatc gcggaaaata
     2521 tcgccgatca tatcgagtcc tttaccgatt atgattttgc tcatttgctt ttctcagacg
     2581 gctcgattac ccaatcgatt agtttagata aacagctaaa tatcattcaa gtggcggatt
     2641 tggttttacc ggatgcagaa acgacttttg aagaatatac caccatggaa ttgcttagtg
     2701 tttcgatgct aatcgtcatt tccacttttg ccttggactt tatccatagt aaccgagaaa
     2761 tcttcaaaat tgtcgatttg gatgaggctt ggagttttct tcaagtggct caaggaaaaa
     2821 cgttatcgaa taagcttgtt cgtgctggtc gggccatgaa tgctggggtc tatttcgtca
     2881 ctcaaaatag cgacgattta ttagatgaac gtttaaaaaa taatatcggg ttgaagtttg
     2941 cttttcgcag taccgatatt catgaaatca agaaaacctt ggaattcttt ggtttggatc
     3001 aggaggatca aagcaatcaa aaacgcctgc gagatttgga aaacg
//
LOCUS       DAPBAF010000109         2988 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.117, whole genome shotgun sequence.
ACCESSION   DAPBAF010000109 DAPBAF010000000
VERSION     DAPBAF010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2988)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2988)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2988
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.117"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(<1..218)
                     /locus_tag="RD451_002852"
     CDS             complement(<1..218)
                     /locus_tag="RD451_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HDT7568027.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMET"
     gene            562..969
                     /locus_tag="RD451_002853"
     CDS             562..969
                     /locus_tag="RD451_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7568028.1"
                     /translation="MSYRVQLIISEDVESQQFGTNVINKVINPALSINAPLIPTALSF
                     SVTAVVSEIEDTEKIKIVEIEVLNKNEKQIFSTGEVSVSLPPQVNDINFNINARNVLV
                     EEAGEHYAVVKFNGTEIGRQIFDIKVNKPVEKN"
     gene            983..1384
                     /locus_tag="RD451_002854"
     CDS             983..1384
                     /locus_tag="RD451_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7568029.1"
                     /translation="MLDIVPSNTHRSGSLINFAAIFACASVILASPVVVDASSTPKTK
                     NDNQLVITTKNEINTISSNDGKIFDVINTVLKRKAEINIKYDEDLNLYFFVIKTTSEL
                     FSSDYDVLDTLDNVLSDYKYMGKSVVATLGE"
     gene            1386..1757
                     /locus_tag="RD451_002855"
     CDS             1386..1757
                     /locus_tag="RD451_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7568030.1"
                     /translation="MFDFNEYLSISKQIESDDKYNSKESYRRTAVSRAYYSAFKKSDE
                     YLKENYDIIYNGSSGKGSHQTVWNLFSTVKELNTLGIHNSGYRMLEKRKCADYIPNET
                     ITKTDMALMNREAEKIINKLT"
     gene            complement(1793..2095)
                     /locus_tag="RD451_002856"
     CDS             complement(1793..2095)
                     /locus_tag="RD451_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7568031.1"
                     /translation="MLMEGKTQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINL
                     YYSNKNYFKIPAAKTRMKKGVYFLFDIVTDVPDARSDHRRYDYIKYTFVDPERYKD"
     gene            complement(2191..2985)
                     /locus_tag="RD451_002857"
     CDS             complement(2191..2985)
                     /locus_tag="RD451_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PH domain-containing protein"
                     /protein_id="HDT7568032.1"
                     /translation="MSKQCAKCGGKIGLTSYKIKDKQIVCGNCMKKAGYGMTTPYKII
                     RSLNLEDLDKDPSEKRKLNISDHTAQNNHDIGNDRMRTTEEMVEFCLKYGYGKGMTKK
                     WTTHHFNLISDQLNSDEYVIFCFVGLHNYISSTKHDNNYAYALTNKRLIVAQQKMIGN
                     NVQSIILDNLNNISKKRGVLLGTLTIDTLGKVLNVAVDKDTVDRISDSLNEIIYNLKR
                     RNISATNSNTSTISSASEIRKYKELLDDGIITEEEFNKKKQELLDL"
BASE COUNT         1036 a          438 c          449 g         1065 t
ORIGIN      
        1 gtttccatat attctataac atcaagttta aattttgtag tgtagctttt gccacctcca
       61 accaagcctt cccaaccatg atagttataa atccttaccc aatgtctaac cagtgtacga
      121 tttatttgat atttatgtgc aagatatttg tagccgcctt cgttatttaa atagtctgaa
      181 actacttttt tcttaaaaac aaatgtatat ttccgcaaaa aaagcacccc ttttaattag
      241 atttctagtc taacttttgg ggtgcacatc atttttgagg ggaagtacat atagttgttg
      301 atatagttgc taatattgtt agctaatttg ttagtaaaac tgtatacgaa tttagatagt
      361 aaaaaaacag tttgttcctt atatagaggc acttttacta ctgattaaat gtcagatatg
      421 cttacaaata tacttataaa tatgcttaca aaattagcta atatttccgt tgacaaagct
      481 ttgttactat tgttaaacta aattgactag caaaagtgaa acataaattt attaaataaa
      541 tgtaaaaatt aggagaaatc aatgtcttat agagtacaat taataatttc agaagatgta
      601 gaaagtcagc aatttggcac taatgttatt aataaagtaa ttaatccagc tctttctatt
      661 aatgcgcctt taattcctac tgctttatca ttttctgtaa cagctgtggt gtctgagata
      721 gaggatacag aaaagataaa aatagtagaa attgaagttt taaacaagaa tgaaaaacaa
      781 attttttcta cgggtgaagt atcggtaagc ttgcctcctc aagttaacga tataaacttt
      841 aatataaacg ccagaaatgt cttggttgaa gaagcaggag agcattatgc tgttgttaaa
      901 tttaatggaa ctgagattgg aaggcaaatc tttgatatca aggtcaacaa accagtggaa
      961 aaaaattaag gagacgatac ggatgcttga tatagtacca tcaaatacac atcggagtgg
     1021 tagcttaata aattttgctg cgatttttgc ttgcgcatcg gtaattctag catctccagt
     1081 tgttgtggat gcaagttcta ctccgaaaac taaaaatgat aatcaacttg taattactac
     1141 aaaaaatgag attaacacaa tttcaagtaa tgatggcaaa atttttgatg tgataaatac
     1201 ggttttaaaa agaaaagctg aaatcaatat aaaatatgat gaagatttaa acttgtattt
     1261 ctttgttatc aaaacaacat ctgaattgtt ttcctcagat tacgatgttt tggatactct
     1321 cgataatgta ttatctgact ataaatatat ggggaaatct gtagtagcaa ctttggggga
     1381 ataaaatgtt tgactttaat gaatatttat ctatttccaa acaaattgaa tcagatgata
     1441 aatataattc taaagaatct tatagaagaa ctgctgtttc aagagcatac tacagtgctt
     1501 ttaaaaaatc tgatgagtat ttgaaagaaa attatgatat tatttataat ggaagtagcg
     1561 gaaaaggaag ccaccaaacc gtttggaatt tgttttcaac agttaaggaa ttgaatacct
     1621 taggaataca taatagtggg tatagaatgt tagagaaaag aaaatgtgct gactatattc
     1681 ctaatgaaac cattacgaaa acagatatgg cgctgatgaa tcgagaagca gaaaaaataa
     1741 taaacaaact cacctaatga atttcaagcg agtttgtttg ttattttttt atttaatctt
     1801 tgtatctttc tggatcaacg aaagtatact ttatatagtc ataacgccga tgatcgctac
     1861 gtgcgtccgg cacgtcagtc acgatatcaa acaaaaagta tacacccttc ttcattctag
     1921 ttttcgcagc aggaattttg aaatagttct tattagaata gtagagattg attaataagc
     1981 tatcttcgat tgctaaaaag aaaacttctg aatcccacac cttataaaaa tctttgacaa
     2041 atctattcga aggatcgaat ttaaaccata attgtgtttt tccttccatt aacatataaa
     2101 gttcacctca aaaagagtat acgaacaaat gtttgtattg taaatagaaa aagatgagct
     2161 aaattaaatg cccatcttct ttgatagata ttataaatct aataattctt gtttcttttt
     2221 attaaattct tcttctgtaa tgattccatc atccaatagt tctttatatt ttcttatttc
     2281 tgaagctgag gaaattgttg atgtattgga atttgtagca gaaatatttc ttctttttaa
     2341 attataaata atttcgttta aagaatcact tatcctatca acagtatctt tatcaactgc
     2401 aacattcaat actttaccaa gagtatcaat agttaatgta cccaacagca ctcctctttt
     2461 tttactaata ttatttaaat tgtctaatat aatactttgt acattattgc ctatcatttt
     2521 ttgttgagct acaattaaac gtttattagt taatgcgtat gcataattat tgtcatgctt
     2581 agttgatgag atataattat gcaatcctac aaagcagaag attacgtatt cgtcactgtt
     2641 aagttgatct gatattaagt taaaatgatg agttgtccat tttttagtca ttcctttacc
     2701 gtagccgtat ttaagacaaa attctaccat ctcttcagtg gttctcattc tatcattacc
     2761 tatatcatga ttgttttgtg cagtatgatc agatatgttt aattttcttt tttctgatgg
     2821 atccttatct aaatcttcta aattcaaaga tcttattatt ttataaggag tagtcatacc
     2881 gtaaccagct tttttcatac aattgccgca aacaatttgt ttatctttga ttttatatga
     2941 agttaagcca attttacctc cgcactttgc acattgttta ctcacatt
//
LOCUS       DAPBAF010000110         2914 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.118, whole genome shotgun sequence.
ACCESSION   DAPBAF010000110 DAPBAF010000000
VERSION     DAPBAF010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2914)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2914)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2914
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.118"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(45..1364)
                     /locus_tag="RD451_002858"
     CDS             complement(45..1364)
                     /locus_tag="RD451_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDT7568033.1"
                     /translation="MKKLKIFPKMFIQIFSVLGIIIILVHSLIFFIFPKTYLETRKEK
                     IHNMANEISSNMNGKEIKYIEQTLEFYSKSSEIKVFIKEKNNKNEIQIKDNINVNLES
                     DSNSLIIEEREIKLNDGKKTNLQFVSTADMQKDAKDLSLKFLPYSLLISILFSAIISL
                     IYAKSIKNNIQEIKIVTDKMMKLDKKMSLKVSSNDEVGELKQQINDLYSTLLRTIDDL
                     EFKNKEILKLEKLKYDFFKGASHELKTPLASLKIILENMKYNIGKYKERDIYINECIE
                     IVDSLTKNISQILSVHSIENLNNDEEYLKINDTLEDILKKYEILANQKKITVNNYILD
                     ENVYIGKTALKIILSNLISNAVKYTDVNGVINIGIVNDWLYIENSYGNNKISNMDKIF
                     DVKFDLNKENSNGLGLYIVSNILNNYNIEYKVLQDEEFFIFKIKIFS"
     gene            complement(1361..2014)
                     /locus_tag="RD451_002859"
     CDS             complement(1361..2014)
                     /locus_tag="RD451_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDT7568034.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLERK"
     gene            2302..>2914
                     /locus_tag="RD451_002860"
     CDS             2302..>2914
                     /locus_tag="RD451_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDT7568035.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGRLDDSP
                     SHCEHCGSIRIIRNGSYTTRTQILKVKEKLTILELKRTRFLCYDCGQTFSAKTDLVDE
                     HHQLTKELKQAILIELYENQSRKLIAKKYFVSDGTVTRILREATKHYQPRMNFLPTVL
                     CMDEFKSMKSVSGSMSFICVDGTTHQLFTILEDRRLYKLTQYFL"
BASE COUNT          955 a          474 c          321 g         1164 t
ORIGIN      
        1 ataagtctct atttttcaat aactattgca aaattatatc ttaattaaga aaatattttt
       61 attttaaaga taaaaaattc ttcatcctgc aatactttat attctatatt gtaattattc
      121 agaatattac ttacaatata taaacctaat ccattactat tttccttatt taaatcaaat
      181 ttaacatcaa atattttatc catattcgaa attttattgt taccgtatga attctctata
      241 tataaccaat cattaactat cccaatatta attaccccat ttacatcagt atattttacc
      301 gcattactaa tcaaattaga tagaataatc tttaaagctg tttttcctat ataaacattc
      361 tcgtctaata tataattatt gacagttatt ttcttttgat ttgctaatat ttcatacttt
      421 tttaatatgt cttctaatgt atcatttatt ttcaaatatt cttcatcatt attcaaattt
      481 tctatagaat gaactgataa tatttgagaa atattttttg ttaaactatc aacgatttca
      541 atacattcat taatataaat atctctttct ttatattttc caatattgta tttcatgttt
      601 tccagtatta ttttaagact agcaagaggg gttttaagtt catgggatgc acctttaaaa
      661 aagtcatatt ttaacttttc taattttaaa atttctttat ttttaaattc caaatcgtca
      721 attgttctta ataaagtaga atacaaatca ttaatttgtt gttttaattc tccaacttca
      781 tcattagagc taacttttaa actcattttt ttatcaagtt tcatcatttt atcagtaaca
      841 atttttattt cttgtatatt attttttatt gattttgcat aaattaaaga aataatagca
      901 gaaaataaaa ttgatattaa taaagaatat ggtaaaaatt taaggcttaa atctttcgca
      961 tctttttgca tatcagctgt agaaacaaat tgtagatttg tttttttacc atcattaagc
     1021 tttatttctc tttcttcaat tatcaaagaa ttactatcac tttctaaatt aacatttata
     1081 ttatctttga tttgtatttc attcttatta tttttttctt ttatgaatac ttttatttca
     1141 ctactcttgg aataaaactc caaagtttgt tctatatatt ttatttcttt tccattcata
     1201 ttactagaaa tttcatttgc catattatga atcttttctt ttctcgtctc caaatatgtt
     1261 ttaggaaaga taaaaaaaat taatgaatga actaatataa ttattattcc aagaacagaa
     1321 aatatttgta tgaacatttt tggaaatatc tttaattttt tcattttctc tccaatttat
     1381 atcctacatt tcttatagta gttatacagt ctaattgtaa tttttttcta agttctttta
     1441 tatatacatc tattactcga tcataaggag tttcttcgct atctttccat acataatcaa
     1501 taatttgcat tcttgttaac acttgtccat tattatccaa taaacatttt aatacttcta
     1561 gttcttttgc atttacatct atttcttcac catttatttt agctgtatag ctattaaaat
     1621 taaccgatag atccttatat tcaaacttct ctaaatgtcc ataattcttc ttaattaaag
     1681 aatctattct agcttttaag accggcaatg aaaatggctt ttctacatat ccgtctacta
     1741 aattagtaaa tgcatcaatt ttatattctt catcactaaa tgcagtcaag attagaattg
     1801 gtaaattgct tttctttcta atttctttca acacttctaa accatttata aaaggtatct
     1861 gaatgtctaa gataaccaaa tttatatcgc tattaaattt tgacaaggct tctcttccat
     1921 ctttagcttg aataacagta tatccaaatt ctgaaagata ttcacttatt ccctctctta
     1981 tcatattatc atcttcaaca gttaatattt tcatatatac ctccacttaa gcctatacac
     2041 tagatattat acagcatatt atggctctat aatatctagt gttggtgaca ccttctgttg
     2101 ccaatacttt ttcttttttc taataaatgc aaacagacac cttgaaatcc tttagaataa
     2161 agggttctat aatattttgt gttgttggaa aatcgaaggc gattttctac taacactttt
     2221 tcttcgtttc aactcaaaaa gagactcact tttggtaaaa tttagtcgac caaaacatca
     2281 ccctaccaaa ggagtcgctc tatggataat catactagaa aattactcgg attaacagat
     2341 aaacatttat tttttgatga agaatggctg attgaaaaag aatataaagg cgttcaagcg
     2401 cagtttatta aagggagatt ggatgactca ccttcccatt gtgaacactg tggatcgatt
     2461 cgtattatcc gcaacggttc ctatacgaca cgtactcaga tattgaaagt caaagaaaag
     2521 ttgactattt tagaattaaa acgtacccgt tttctatgct atgattgtgg gcagaccttt
     2581 tctgcgaaaa cggacttagt tgatgaacat catcaactaa caaaggaact gaagcaggcg
     2641 attctcatag aactgtacga aaatcaatca cgtaaactaa tcgctaagaa gtacttcgtc
     2701 tcggatggga cggtgacacg gatcttgcgt gaagcaacga agcattacca gccacgtatg
     2761 aacttccttc cgacggtgtt gtgtatggat gagttcaaat caatgaagtc tgtttctggt
     2821 tccatgagtt ttatttgtgt tgatgggaca acccatcagc tatttacgat ccttgaagat
     2881 cgcagacttt acaaactaac tcaatacttc ctgc
//
LOCUS       DAPBAF010000111         2861 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.119, whole genome shotgun sequence.
ACCESSION   DAPBAF010000111 DAPBAF010000000
VERSION     DAPBAF010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2861)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2861)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2861
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.119"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            4..2376
                     /locus_tag="RD451_002861"
     CDS             4..2376
                     /locus_tag="RD451_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7568036.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLARLQNELNEQIEKMFEHQRKTNGQ
                     PMNDKRNGHSWFRQQERLENKVHSLREEIKQQEKQVEKLERQEELKEMGYNKYGGLDM
                     TIDNIPRIKEEIERFEKGESTFSAATIRKYQRKLETLEQLKEKSEKGKENILPEVQAI
                     IDSGRVTQWKKNPTIYFLKGYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     APTDSLKEKEKDHFYRVEFNENDPEKGLKSYGGEIVTLELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNHPIYLELAKLCEQVPEKEQKQSVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSSEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DKKGQSELQAGIQAVANNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTPTQHLATSIHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTSEKAIPYI
                     AAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQE
                     HKNTLETPENKNIVPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGK
                     SYGKEIQTALPSEEFALGNPFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            2437..>2861
                     /locus_tag="RD451_002862"
     CDS             2437..>2861
                     /locus_tag="RD451_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7568037.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDPKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYA"
BASE COUNT         1145 a          457 c          616 g          643 t
ORIGIN      
        1 gacatggcag aagaaaaaga accactagac aatagtcgtt tgggaaaatc caaaagaaaa
       61 ttagcacgat tgcaaaatga actaaacgaa caaatcgaaa agatgtttga acaccaaaga
      121 aagaccaacg gtcaaccaat gaacgataag agaaatgggc attcttggtt taggcaacaa
      181 gaacgtttag aaaacaaagt gcatagtctg agagaagaga tcaagcaaca agaaaaacag
      241 gtagaaaaac ttgaaagaca agaagagcta aaggaaatgg gctataacaa gtacggcgga
      301 ctggatatga cgatcgataa tattccaaga atcaaagaag aaatcgaacg ctttgaaaaa
      361 ggtgaatcga ctttttcagc cgccacgatc cgaaaatatc aacggaagtt ggaaacatta
      421 gaacagctga aagaaaaatc agaaaaagga aaagaaaata tcctccctga agtacaagcg
      481 atcattgaca gcggacgagt gacgcaatgg aaaaaaaatc caaccattta ttttttgaaa
      541 ggctatcgaa aagttgcttt agaactgaat gaaaacgggg gatttgagga atcaaaaaaa
      601 taccaagcca cgtcggaaga ggaaaaagca gctgttcgtg aattacttga agaggctgca
      661 ccaactgatt ctctgaagga gaaagaaaaa gatcatttct atcgagtaga attcaacgaa
      721 aatgatccag aaaaaggatt gaaaagttat ggtggggaga tcgtaacatt agaattgatc
      781 gatcaactta aaacgttgga taaccaatac gctgcagaag caggttatta taaattctat
      841 tttgaagaag tgaagaacgg agaagtagta gatcagatcc gaatggatct aggggatggc
      901 gtcaacagta atcaccccat ctatttagag ttagcaaaat tgtgcgaaca agtacctgag
      961 aaggaacaaa aacaatcggt caaaaatgaa cctgtttcga aagaacaaat gcagtcgaaa
     1021 gaaacaaaaa caaaacaaaa gggctatcaa aaacgaacgg cagaagagat caaacaagaa
     1081 gttaaatccc tttcgcaaca ggcactggat gcggtgaaaa agcataccca ttcttctgaa
     1141 gacgtcaaag aacttttgaa ctttatgtct cgttttccag aacgatcctt tagaaatcaa
     1201 ttattgattg aggaacaatt tccaggtgca acggcttgtt taggtcgtgc cgcgttgaaa
     1261 aaagaaggaa tctatatcaa aaaaggggaa caagggaaca agatctttgt cagaaaaacg
     1321 gtcaaaggat tttatgagaa aggacgtggc tttgttcgag aaacagaagc tacaccagaa
     1381 gataaaaaac gaatcgaaag tggtcaaatc gaagtgatca aaaaacctta ctacacgatt
     1441 gaaaaagtgt ttgatatcac acaaacacag ttaaaacctg aagactatcc gaaaatcttt
     1501 ccgaaccgtg tctttgattt tcaattggat aaaaaaggac agtcagaact tcaagctggg
     1561 attcaagcgg tagccaacaa tattggaata caaattcgag atatgacaga aagtgaagtc
     1621 tatcaaagag aattaggaca agcacgtggg gcgtatgttc gtaacgaatt tactggcgaa
     1681 gaagaaatcg tcatgaatac tcgaaatact cctacgcagc atttagctac aagtattcat
     1741 gaattagccc atgcaagaat gcacaaattt tcagaattag ataccgcaac taaagaattg
     1801 caggcagaaa tgacttctta tattgtgtgc aaacattttg gaatggacac gtcggagaaa
     1861 gctattcctt atattgcagc atggacgaag aatggtcaga cgttggatga taaggaagcg
     1921 gcggaacgtg ggaaaatcat gaatgatgtc agtcgtgtcg caaatgaatt cattcaaacc
     1981 atttctaatg aaatcaatca atacagagaa agagaaccag agatccagcc agcagaagtg
     2041 aagcaggagc ataaaaatac tttagaaacg ccagagaata aaaatattgt gcccgttggt
     2101 tcactttgga tcgacaagaa agacgggaaa gtaatggaag aagatacggg tcgaacgtta
     2161 catttgaagg atgcggcgtt tattgaagat ccgcagcata atcaagtaat tttaaaagga
     2221 aaaagttatg gaaaagagat ccaaacggcg ttaccttcag aagaatttgc gctaggaaat
     2281 ccattccgat tttcacttga gacagtgtca gaagtggcaa aacgaaaaaa tgaaatctat
     2341 tatgaacaac aattgtcaca aaaagaacgt gtataaaaca agtaaaaaag actatctgaa
     2401 aaacggatag tcttttttct tttgggaggt tttaaaatga ccgagaaaaa aatgagtctt
     2461 attgatcgat gtaaacagat cgatatagtg gattttgctc gaaacaatgg aatggctgta
     2521 gtcaataaag gacgagatta tcgcttagaa gaccatgatt catttgtttt tgatcgaaga
     2581 aaacaacgtt tttattggaa cagtcaaaat attagtggcg acattattga attagctaaa
     2641 ctttttttca tagacaaaga gatccaagac cctaagcaac aatttaaagc agccactgat
     2701 tttattctaa agaatgaaga caaaacagaa cgagtggaaa atcttcattt tgaaacagaa
     2761 aagtacaaag atcaccccgt tgattatcaa ccactcacag aaaaaggaag gaattatctg
     2821 aaggaagaac gaaaactacc agagtggctg attgattatg c
//
LOCUS       DAPBAF010000112         2810 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.120, whole genome shotgun sequence.
ACCESSION   DAPBAF010000112 DAPBAF010000000
VERSION     DAPBAF010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2810)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2810)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2810
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.120"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            95..1054
                     /locus_tag="RD451_002863"
     CDS             95..1054
                     /locus_tag="RD451_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element IS1252 family transposase"
                     /protein_id="HDT7568038.1"
                     /translation="MTYTHLTTDELVMIESYYHQNIKIVKIAEYLKRSRTPIYNVINF
                     LKEGHTALEYYQQYKENKKRCGRRNIVLPKKQQSYIKEKIAQGWTPDVIIGRKEKPIS
                     CSVRTLYRQFKEKVFDESTLPMKGKRKPNGHQERRGKQAFKRNIVERETDYPTFKEEF
                     GHIEGDTIVGIHHKSAVITLVERLSKIIITLKPEGRKAIDIENTLNHWFGSIPRHLFK
                     SITFDCGKEFSNWKALSNQHDIAIYFADPGTPSQRALNENSNGLLRKDGLPKNMDFNQ
                     VDQAFISSVANKRNNIPRKSLDYQTPLEVFMSYMNEDILSSLI"
     gene            complement(1487..2059)
                     /locus_tag="RD451_002864"
     CDS             complement(1487..2059)
                     /locus_tag="RD451_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDT7568039.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGTKRD
                     RPKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTS
                     MGRMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELL
                     TSGKSYKEVEAITGFSRSTLFRIKKKIEES"
     gene            complement(2075..2680)
                     /locus_tag="RD451_002865"
     CDS             complement(2075..2680)
                     /locus_tag="RD451_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell filamentation protein"
                     /protein_id="HDT7568040.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTF
                     KGLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEII
                     KKYVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDL
                     EIRYLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
BASE COUNT          885 a          576 c          466 g          883 t
ORIGIN      
        1 gccgattgta aaattaagct agacaaataa ataagccatt cgtgctacac tcaaaatgta
       61 attccgacta aagaaaacat aggagtgatc acgaatgacc tacacccatc ttaccacgga
      121 tgaactggtg atgatagagt cttactacca ccaaaacatc aaaattgtga aaattgctga
      181 gtacctgaaa cgatctcgaa caccgattta taacgtcatt aatttcttga aagaaggcca
      241 tacggccctc gaatactacc aacagtataa agaaaataag aaacggtgtg gcagacgaaa
      301 catcgtcttg ccaaagaaac aacagtccta cattaaagaa aaaattgccc aaggctggac
      361 gccagacgtt atcattgggc gtaaagagaa accaatcagc tgttccgtaa gaacccttta
      421 tcgccagttc aaggaaaagg tgttcgatga atcgactttg cccatgaagg gtaagcggaa
      481 accaaatgga catcaagaac gccgaggaaa acaggctttt aaacggaata tcgttgaaag
      541 agaaactgat tacccgacat ttaaagaaga gttcggccat atcgaaggcg ataccattgt
      601 aggcattcat cataagagtg ctgtcataac tttggtagaa cgtctatcga aaatcatcat
      661 caccttgaag cccgaggggc gcaaggcgat cgatattgag aatactctga accactggtt
      721 tggatcgatt cccagacatt tatttaaatc cattaccttt gattgtggga aagaattctc
      781 taattggaag gctttaagta accaacatga catcgctatt tatttcgctg atccagggac
      841 tccttcgcaa cgagcactga atgaaaattc caatggcttg ctgcgaaaag atggtctgcc
      901 aaaaaacatg gattttaatc aagtcgacca agcttttatc tcttcagtgg cgaataagag
      961 aaacaatatt ccacgaaagt ccttggatta tcaaacaccc ctggaagtat ttatgagtta
     1021 catgaatgaa gatattttgt ctagcttaat ttgacaaatc aaattattta aaactttgca
     1081 acagaacctt agcagcagtg ctgattttta tgatagttat ttggttctta aatgaaagat
     1141 ctaaagacaa tcaacaccgt agggatatgg agataaaatc aatagagtca atagattatt
     1201 tatcgataat aacactaaaa aagccacgtt cctaaacgtg acttacgctg aacgatatgt
     1261 gttgtttggt agacgaacaa atcgttcatt ataaatatat gatggtatcc taatatagta
     1321 agcgtggcta gcataccttt aattacttta ccttttacag ttaccataca cattttttga
     1381 gcagaaatca agtaaataaa aaaatattat atttcacaac atgctaatag actcatatct
     1441 agaacgcatt aagtatttac ctgtctggtt cgctgagact tcttttttaa ctttcttcaa
     1501 ttttcttctt tattctaaaa agcgtactgc gactgaaacc ggttatagct tcaacttcct
     1561 tatacgattt acctgaagta agcagttcat atgcgtgcct cttcttcggt gtgattgttg
     1621 ctttcggacg tccttctctg aaattaggat tattctttct tgcaaacatt tttccttctt
     1681 gggtacgttc cacaatcata tcacgttcca tttctgctac actcaacaac gtccgtgtca
     1741 ccattcgccc catggacgta ttttcaatcg ttcctagatt caaaaccttg atcgttacgt
     1801 tatcatcgag taaaggttca atgatctcta atgcttctct cgtgttacga gcaaatcgat
     1861 caagcttcgt aacaactatt tcatctccag gcttcagacc agccaacagc tgattgaatt
     1921 ttggccgatc ccgttttgta cccgtaaatt tttctgaaaa aatattcttc ttctctacgc
     1981 cgttctcaag caactgttga atttgttctt ttgtactttg agaagcggtt gagacacgtg
     2041 catatccata tttcgtcatt tggtccacct acttttacaa atcatctatc gtatactcag
     2101 aatacccttc atagaaatag ctgacatcga ttcctttcat atataactcg cgatcgtcaa
     2161 ttttatcagt cagagcattg gaaattagat agcgtatttc caaatcgttt atgggacttc
     2221 gctccattgc agaaagatag tctgctttat cgattaagtt ccaatctaca actttttgca
     2281 attcttcctt taaaatgaga tccagccaaa ttctagtact tcggccattt ccttctcgaa
     2341 atgggtgagc gatattcatc tccacatatt tcttgataat ctcttcaaaa gaagtttgtg
     2401 gcatctgatc aatatgctgt aacgaatgtt ctaaatacat aactggtgca aatcgaaaat
     2461 ttccttttgc aatattgacc gatcggattt ttccggcaaa atcgtaaata tccgaaaata
     2521 gaaattcatg aatttcagat aaacctttaa atgtaccaac ttcgatttca tttatttttc
     2581 cacaatcgta caattctttc gctttttgtt tactgagttt ttcttcaacc ttagccaact
     2641 caacttgatt ggttaatccc aatttattct ctaaaatcat gcgaaatctc cttaacttta
     2701 tgacataagt ttatgaaaca ctctcaaccc cattatatcg cgattttgtt tatgtgtcaa
     2761 aaactattaa gtttctgacc cccgatagat ttttcaagtg tctctatttt
//
LOCUS       DAPBAF010000113         2633 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.121, whole genome shotgun sequence.
ACCESSION   DAPBAF010000113 DAPBAF010000000
VERSION     DAPBAF010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2633)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2633)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2633
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.121"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            5..1149
                     /locus_tag="RD451_002866"
                     /pseudo
     CDS             5..1149
                     /locus_tag="RD451_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
     gene            1320..1778
                     /locus_tag="RD451_002867"
     CDS             1320..1778
                     /locus_tag="RD451_002867"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HDT7568041.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            1937..2407
                     /locus_tag="RD451_002868"
     CDS             1937..2407
                     /locus_tag="RD451_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HDT7568042.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
     gene            complement(2460..2575)
                     /gene="rrf"
                     /locus_tag="RD451_002869"
     rRNA            complement(2460..2575)
                     /gene="rrf"
                     /locus_tag="RD451_002869"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT          863 a          504 c          496 g          770 t
ORIGIN      
        1 aaacatgcac attcaaacaa aattgatcca cggaggcatc agtgaagatc ccacaacagg
       61 agctgtcagt gtacctattt atcaaacatc cacttatcgg caagatggcg tcggccagcc
      121 taaacaatat gaatattcaa gatctggtaa tcctactcgt tttgcattgg aagaactgat
      181 tgctgatttg gaaggcggtg ttcgaggatt cgctttttct tctggtcttt ctgggattca
      241 tgccgttttt tctctttttc aagctggcga tcatatctta ttaggagatg atgtctatgg
      301 aggaacattc cgtctatttg acaaagttct tactaaaaat ggtctcgagt acacgatcat
      361 agatacgagt aatcttgata aaatagaaca atccatcaaa cccaatacaa aagcacttta
      421 tcttgaaaca cctagcaatc cgcttctaaa gattactgat ttagaaaaaa gtgccactct
      481 ggctcatcaa catggattga tagttattgc tgacaataca tttgctactc cttattttca
      541 aagaccttta gatctcggtt ctgatatcgt tgtccatagc ggtaccaaat atctaggcgg
      601 acacagcgat gtagtagctg gtttagtgac ttctaaccaa aagatctagc cgatcagatc
      661 ggattttacc aaaatgctat cggagccgta cttggtcccc aagatagctg gttacttcag
      721 cgcggaatca agacactaag tgttcgtatg gaggaacatc aaaaaaatgc ttttgtggta
      781 gctgattttc tattttctca tccagcagta gaaaaggtct actatccagg attacccgat
      841 catgaactcc atggagttgc taagcagcag atgagcggct ttagcggaat gatttctttt
      901 actttaaaaa atgaagaatc tgctattcca tttgttgaat cactccaact atttacttta
      961 gcagaaagtt taggtggcgt agaaagttta gtggaaattc cttctgtcat gactcatgcg
     1021 tctattccaa aagaaaaacg agaagaggct ggcataaagg acggcttgat ccgtctttct
     1081 gtaggaattg agtatggtca ggatctcata aacgatttag ctcaggcatt tgacagaatc
     1141 aagaactaga agtcccaata aacgacttag cagaaaaatc taaaaaatat ttcagattgc
     1201 tacaccttgg aaacgataag tgttagaatc aagtagaaag acgtttttgt aaatttcact
     1261 aaataattct ttagtgaaaa gcatcaaaac gaatgaacaa acagatagga gtcttacaaa
     1321 tgagaatgaa tgtcgaaagt tttaatcttg accatacaaa agtcaaagca ccttatgtac
     1381 gtgtagctga tcgaaaaacg ggtgcgcatg gcgatgtcat cattaaatac gacgtccgct
     1441 ttaaacaacc aaataaagaa cacatggaca tgccaagtct acattcactt gagcacttga
     1501 ctgccgaact aatccgcaat cacgcagatt acatcgtaga ctggtctcca atgggatgcc
     1561 aaacaggctt ttacttgact gtattgaatc atgaaagcta cgaagacatt ttagatgttc
     1621 ttgaagcaac aatgaaagat gttcttgaag ctactgaagt acctgcaagc aatgaaacac
     1681 aatgtggctg ggctgccagc catacactag aaggtgcaca agctttggct cgtgaatttt
     1741 tagcaaaacg cgatgaatgg tctgaagtag aagcatagtt tctaaaagaa cgtaaagatg
     1801 agaagcaata tagctatctt atcttcgtat tttattaaat atttattgtc tgaaaagagt
     1861 tctaaacggg aaaacaaata gctagttttc agtttagcgc tctttttatt atataaaata
     1921 gaaaggagaa aactttatgt ctatttataa ttttgaaact actttagaag acggcactgt
     1981 ctattcattg aaaaaatatg caggcaaacc gataatcatt gttaacactg caacaaaatg
     2041 cggtctagca cctcaattta aacaattaga agaactttac caagcttatc agacacaagg
     2101 tctggttatc ttaggctttc cttccaatca atttaaacaa gagctagatt cagcgactga
     2161 agcagcagaa gcttgtaaaa ccacttatgg cgttaccttc cctatgcatc aattgattga
     2221 cgtaaatgga gaaaatacag atcctctttt tacttatctt aaaaatgaag ctcctggtac
     2281 tgtcactaaa gcaataaaat ggaattttac taaatttttg attgatagaa atggcaaagt
     2341 aatcgaacga tttgcaccac aaacttctcc attgaaaatg accgctgcaa ttgaatccgt
     2401 tctttaactt aataaaaata aaaaaagatg aactatttct agttcatctt tttgcctttg
     2461 cgtggcgacg tcctactctc acaaggggca acccctcact acaatcggcg ctaagaagct
     2521 taacttctgt gttcggcatg gttacaggtg tatccttctc gctatcgcca ccacactgtg
     2581 gtgttatctt ttattgagta aattttgttc actcaaaact ggatttgaag tca
//
LOCUS       DAPBAF010000114         2617 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.122, whole genome shotgun sequence.
ACCESSION   DAPBAF010000114 DAPBAF010000000
VERSION     DAPBAF010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2617)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2617)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2617
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.122"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(492..1784)
                     /locus_tag="RD451_002870"
     CDS             complement(492..1784)
                     /locus_tag="RD451_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HDT7568043.1"
                     /translation="MARKKRNPDAEKLAESILNAYQPESVDDMQDALKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKEHDNRRNGYGTKTLKTSFGEVAIDVPRDREASFEPELIP
                     KRKRDVSDIEGKVLSMYARGMSQRDIAATVEAIYGFDISHEMISDITDAVLPELEEWQ
                     ARPLAKCYAFLFVDCMYVTLRENYEAKEYAVYTILGYDLKGNKEILGLWLNQTESKNR
                     WMQVFDELKARGVEDVFFISMDGVSGLEEGAKAIFPSVIVQRCIVHLVRNALRYIPSK
                     DYKEVCRDMKKFYGASSLNAAHAAFDSFQNRWSHYSGAVDVWKRNFAHVEQLFDYGSA
                     IRKIMYTTNAVESVHSSFRKVTKKGAFSNENALLKLLYLRTKELHAKWSGGRIQNWAM
                     VLNQLMINETFSSRMKSMRFTFRNNGRFIQLCVRSKFI"
     gene            complement(2058..2318)
                     /locus_tag="RD451_002871"
     CDS             complement(2058..2318)
                     /locus_tag="RD451_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7568044.1"
                     /translation="MKKIDLINMIGMLIGILVNIVIFTDWLGVLFSNLIPILIIGICG
                     IILSILELFESRNTMNRIFACIILIVNLLPMVYFTFLYFALG"
BASE COUNT          886 a          483 c          398 g          850 t
ORIGIN      
        1 tatattataa attcacatga ttatcgaatt ttattaagtt agtttttctt gtaaatctct
       61 gttcccaatg aaactcgaga cacttatttt aaagaggaaa caatgtggta tttaaatagc
      121 cctcttgtat gggctactct gtgatactta ttagccatta aactatttta cccacatagc
      181 atatattttg aaatcgttca ttccgtaaat tcaactaaat atgcctaaaa aaataaaaaa
      241 tctaagatag aataagattt attcagtctt agatggattt atagcaactt tttcgtaaca
      301 actttaaaaa atacgaaaag aaagagctgt tttactctga ctacgttgct aaattgtcgt
      361 ttaatcattc atttaaacca aatctttttt tatagaattc gttttaatcc tcctgaatcc
      421 aaaaactatg aaaaccgtaa ttaaatagtt aagagttttt aaccaccata attctctcgg
      481 ctattttgaa atcagataaa ttttgatcgg acacatagtt gaataaacct accgttgtta
      541 cggaaggtaa atcgcatact tttcattcta gaggagaagg tctcgttgat cattaactga
      601 ttaagcacca tagcccagtt ttgaattcga ccacctgacc acttcgcgtg taattctttc
      661 gtgcgtaaat aaagtagttt taggagtgca ttctcattag agaacgctcc tttttttgtg
      721 acttttctga agctggagtg gacactttca accgcattgg tagtgtacat aatttttcga
      781 atggcactac cataatcaaa tagttgttca acatgtgcaa agttccgttt ccagacatct
      841 acagcaccag aataatgaga ccaccgattt tgaaaactgt caaaagcagc atgtgcagcg
      901 tttagagaag aagcaccgta gaactttttc atatctcggc agacttcctt atagtcctta
      961 cttggaatat agcgcaatgc atttcgaaca agatgaacaa tacagcgctg aacaattacc
     1021 gatggaaaga tcgcttttgc gccttcttcg aggccagaaa caccgtccat cgaaatgaaa
     1081 aagacatctt cgacaccacg tgctttcagt tcatcaaata cttgcatcca gcgattttta
     1141 gattctgttt gatttaacca taatcctaaa atctccttat ttcctttgag atcatagcca
     1201 agaatggtgt atacagcata ttctttggct tcataatttt ctcgtaaagt aacatacata
     1261 caatcaacga atagaaaggc ataacacttt gctagggggc gggcttgcca ttcttccaat
     1321 tcaggaagga cagcgtcagt gatatctgaa atcatttcat gggaaatatc aaagccataa
     1381 atagcttcga cggttgcggc aatatctcgt tgactcattc ctcgtgcata catggaaaga
     1441 accttccctt cgatgtcgga gacatctcgt tttctcttag gaattaactc tggttcaaag
     1501 gaagcttccc ggtctctagg aacatcaata gctacttcac caaaactggt tttaagcgtt
     1561 ttagttccat agccatttcg acggttatcg tgttccttag gctctttaga atgggcatca
     1621 taacctaaat gattattcaa ttctccttga agcatttttt caaaaagggg cccaaacaca
     1681 tctttcaaag catcttgcat gtcatcgaca gattcaggtt gataggcatt cagaatggat
     1741 tcagctaact tttcggcatc aggatttctt ttctttctag ccatcgtgta atcacctctt
     1801 gatcttattg tagaaaaaga aaaaccgcga agcaaccacc tgcctaggat taatggttac
     1861 ttacacggtt tatattacac tctcatcatt aaaaaagtat ctttcgatat tactaaacaa
     1921 tgaaattatc tatttgaaat ttaaatctga taatatattg agtgttccaa tgagggcttt
     1981 gatcctatta tccatatctt tttcagtttt aatattgata cacattataa gaaaaagaaa
     2041 cttttggtta atttatttca tcccagtgca aaatataaaa aagtaaaata gaccataggc
     2101 aatagattaa caattaatat aatacaagca aatattctat tcattgtatt tctgctttca
     2161 aaaagttcta atattgaaag tataattcca caaatgccta taataagtat gggaataaga
     2221 ttagaaaata acaccccgag ccaatctgtg aaaattacta tatttactaa tatccctatt
     2281 aacataccta tcatatttat taaatcaatt tttttcatta gatatttctc ctttattaaa
     2341 tctgaagtac ttatattaaa ataattctaa actatttacc tcaaaaagtg caataaatta
     2401 tttctgaaca ataaaatgat agtcaaaaca aaaaaatatt gttaatcgtt cagagccatc
     2461 cgagagtgta aaatattttg tgtaaatgaa aaaatccata caaaaaagga aggcgcttct
     2521 gtagaataaa gttaacgaca accaattcac agaaaagagg acttccctat gaatgatttt
     2581 actacagaaa ttgtgcaaac tctagtcact aaaggcg
//
LOCUS       DAPBAF010000115         2400 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.124, whole genome shotgun sequence.
ACCESSION   DAPBAF010000115 DAPBAF010000000
VERSION     DAPBAF010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2400
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.124"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            207..2069
                     /locus_tag="RD451_002872"
     CDS             207..2069
                     /locus_tag="RD451_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDT7568045.1"
                     /translation="MQQLTKRERQLLIYLVEMSEPVTIKKLAEKENVSVRTIKYDLDD
                     IREWLNERKQVLYSKRSQGIWMNISSSDRIKLKSELMDVNRFEIFADQSLRIKRLLIM
                     LLVTKEAITGMKMANALDVSKDTIMNDLDVLENNFLKEGLTLNRQARKGFWIIGEERL
                     VRLTIEEILQKEFTDYDIYKLMSLLLNGGETEYFEMYSATATPIQEVFNQVIIRMRHL
                     LEFENLEKLNYAELLNILIRVTIATVRLRKEATIGRYQLVAEQELDKNDLSYRVMQQV
                     FDYYQLPLFEDEYHYIYSDTFDTIHQQDVMKLVENVIYKVSKAINHSFYQDPQLLTNL
                     YAHLSMRLSRKKKFVNEYNPFKEDIKQKYPELFDAIKQAVRQEISEQNILINDSFVAY
                     IALHFLVSYEREEDLRSVRAVYICSTGLGVTSLIKQKINEELNNITIVAFASVLNAQE
                     MIATKDPDLVISIFPINGIDRPFIKVHPLPTEQDLKKIQQIIKKILASSNQQERHNLN
                     LRETSINKDTLEDFSKELILKAYTIYERLLVILEAELIQEYREAFLLHVFLMVHRITF
                     DQQYMAEGRQVDQIILDKGTLVGKIEAVFAENNLGINQSEISALFSYIKEGASS"
     gene            2069..>2400
                     /locus_tag="RD451_002873"
     CDS             2069..>2400
                     /locus_tag="RD451_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDT7568046.1"
                     /translation="MKMSDEALKIIEESQNREKLKQVIDLIEERLVEHAIVPTELQWT
                     ILINHLNEMLKRSQRKETIPVVDRDLFKEVSKEAITISDEIVRSIGNLTDDEIYVLSI
                     HFETAKNN"
BASE COUNT          866 a          353 c          466 g          715 t
ORIGIN      
        1 aaaaatttga aaaagcgttt gattatttat attacgactt agtgcaataa aaaacgcttt
       61 ttaacagtac atgtagtcgt ctttataata gataaactct gtaatattag ttaaaaagct
      121 ataagttgca cttagttaag tgcaaacatt tcatattgtc gttagtttag aaaacgctta
      181 tattagcaat gtaaggagag atgataatgc agcagctaac aaaaagagaa aggcagcttt
      241 tgatttactt ggtggaaatg tctgaaccgg taacaatcaa aaagttggct gaaaaagaaa
      301 atgttagtgt tcggacgata aaatacgatc tagatgatat aagagagtgg ctgaatgagc
      361 ggaagcaagt cctatatagc aaacgtagtc agggaatttg gatgaatatt agtagctctg
      421 atcgaatcaa attaaaaagc gaattgatgg atgttaatcg ttttgaaata tttgcagatc
      481 aaagtctccg aatcaaacgt ttactaatta tgcttttagt aacaaaagaa gctattactg
      541 gaatgaaaat ggccaacgca ttagatgtca gcaaagatac gatcatgaat gatttagatg
      601 tgctggaaaa taattttctt aaggaaggat tgaccttgaa tcgtcaggcg cgaaagggtt
      661 tttggatcat aggagaagaa cgtctagttc gattaacgat tgaagagatt cttcaaaaag
      721 agttcacgga ttatgacatt tataaattaa tgtcattgtt attgaatggc ggtgagactg
      781 aatactttga aatgtattct gctactgcta cacctatcca agaggtattt aatcaagtaa
      841 tcattcgaat gcgacactta ctggaatttg aaaatctaga gaaactgaat tacgcggaat
      901 tactaaatat tctgattcga gtgacaattg ctaccgttcg cttacgcaaa gaggctacga
      961 ttggtcgtta tcaattggtt gctgaacaag aattagacaa aaacgatctt tcttatcgcg
     1021 tcatgcagca ggtctttgat tattatcagt tgccactgtt cgaggatgaa tatcattata
     1081 tctatagtga tacattcgac acgattcacc agcaagacgt catgaaacta gttgagaatg
     1141 tgatttataa agtaagtaaa gcaatcaacc attcttttta tcaagatcca caattgttga
     1201 cgaatctgta tgctcattta tccatgcgat tatcgagaaa gaaaaaattt gtcaatgaat
     1261 ataatccttt taaagaagat atcaagcaga aatacccgga attatttgat gcgatcaagc
     1321 aagcagttcg acaagaaata agtgaacaaa atattctgat caatgattct ttcgtggcat
     1381 atattgcctt acactttttg gtttcctacg aaagagaaga agatctacga agcgttagag
     1441 ccgtctacat ttgttcaaca gggttgggtg tgactagtct gatcaagcaa aagatcaatg
     1501 aagaattaaa taatatcact atcgtggcat ttgcttcagt attgaatgcg caagaaatga
     1561 ttgctaccaa agatcctgat ttggtgatta gtatttttcc aattaatggc atcgatcgtc
     1621 ctttcatcaa agtccatcca ttacccactg aacaggactt gaaaaaaatt caacaaataa
     1681 taaaaaaaat acttgcttct tccaatcagc aggaaaggca taacttgaat cttagagaaa
     1741 cgtccatcaa taaagatact ttagaagact ttagcaagga attgattttg aaagcttata
     1801 cgatttatga acgtttactt gtcattttgg aagcagaatt gatccaagaa tatcgagaag
     1861 cttttttgct tcatgtattc ttaatggttc atcgtatcac atttgatcaa caatatatgg
     1921 cagaaggtcg tcaagtagac cagattattt tagacaaagg aacactggta ggaaaaatcg
     1981 aagcagtttt tgcagaaaat aatttaggaa tcaatcagtc agaaatcagt gcattattct
     2041 catatataaa agaaggagcg tcaagttagt gaaaatgtca gacgaggctt taaaaattat
     2101 cgaggaaagt caaaatcggg aaaagttaaa acaagtgatt gatctaattg aagagcgatt
     2161 agtagaacat gctattgtac caaccgagtt gcagtggacc attctaatta atcacttgaa
     2221 tgagatgctg aaacgttctc aaagaaagga aacgattccc gtagtcgatc gggatttgtt
     2281 caaagaagta tccaaagaag ccataactat ttctgatgaa atagttagaa gtatcggtaa
     2341 tttaaccgat gatgaaatat atgttttgtc gattcatttt gaaacagcaa aaaataatta
//
LOCUS       DAPBAF010000116         2364 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.125, whole genome shotgun sequence.
ACCESSION   DAPBAF010000116 DAPBAF010000000
VERSION     DAPBAF010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2364
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.125"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            <1..903
                     /locus_tag="RD451_002874"
     CDS             <1..903
                     /locus_tag="RD451_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HDT7568047.1"
                     /translation="GFTKQSACGILGNIQQETGGTFDPDTVQIGGPAYGLVQWDGSSY
                     PLVGPATWDGKVYVQNLFNAAGIKEPITSLDAQVRLLIWTFTNGQWMGVVQPTTVDGF
                     KACTDPRQAAYAFERNYERPAATHPERQDYAVNWYNKFKDLKPGGATGEAGLKHLESL
                     IGQRIGNGQCYGLSAEYSGYLGGCGMGAGTKYGLTHVIGNTSAASDIGIAYDWSAVGW
                     KVIQNPRYDQLVVGAIINWARGGQVGSWFADGTYGHTGVIRGLANGRMQTYEQNTELG
                     MICGKLDRQYYSASAISSIVIPPK"
     gene            916..1824
                     /locus_tag="RD451_002875"
     CDS             916..1824
                     /locus_tag="RD451_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HDT7568048.1"
                     /translation="MAKWNVILSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETRIVDAKKGKIKYIFDKYSMQCLHRQTANFIIFKGED
                     LIGTTQDFSYFVINAVSKTEGEMGSYWQSIEDLIADMTDFINENKGDFTDWMNERKEE
                     FDRWREEQENSFQDWREGQESDYLSWFESIKDILKSIDPGGVMLAELMDARVDIQGVR
                     HASISERLLADMDYLYQKLRATLFTIEYGEIEVTDILQDDLFSDNHEVEKVGTVEFPI
                     EEGALIIATVDDPKQNVFTLEKVGVI"
     gene            1824..>2364
                     /locus_tag="RD451_002876"
     CDS             1824..>2364
                     /locus_tag="RD451_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7568049.1"
                     /translation="MVKVKRMMETDESGVKRQFMPITHVSAVLGLEKMISGQSKVLSV
                     NGKYGAVILTKADLGLENAITELPYASETSDGILTAEMFQKIVNGEGGTYILPIATPE
                     QLGGIKVGELLEVTEEGVLSATKQTDFNFSEELKGKLESLKILKAGANISIAEDGTIS
                     STGGSGTGGVNQSYVDQKFQ"
BASE COUNT          795 a          329 c          546 g          694 t
ORIGIN      
        1 ggatttacga aacaatctgc atgtggaata ttggggaaca ttcaacaaga aacaggagga
       61 acttttgatc ctgatactgt tcaaataggt ggaccagcat acggattagt tcagtgggat
      121 ggttcttcat atcctcttgt tggtccagca acatgggatg gaaaagttta tgttcaaaac
      181 ttatttaatg ctgcaggtat taaagaacca ataacgagct tagatgcaca agttcgattg
      241 cttatttgga catttacaaa tggacaatgg atgggcgtag tacaacctac gacggttgat
      301 ggatttaagg cctgtactga tccaagacaa gcagcatatg cttttgaacg aaactatgaa
      361 cgtccggcag cgacacatcc tgaacgtcaa gattatgcag ttaactggta taacaaattt
      421 aaagatttaa aaccaggagg agctactgga gaagcaggac taaaacattt agagtctttg
      481 attggacaac gaattggcaa tggtcagtgt tatggcttgt ctgcagaata ttcaggatat
      541 ctgggtggtt gtggcatggg tgctggaaca aaatatggtt taactcatgt gataggaaat
      601 acttctgcag catctgatat tggtattgcc tatgattggt ctgctgttgg ttggaaagtg
      661 attcaaaacc ctagatatga tcaattagta gttggtgcaa ttattaattg ggcaagaggt
      721 ggacaagtgg gttcatggtt tgcagacgga acttatggac atactggcgt tatccgaggc
      781 ttagctaatg gtcgtatgca aacttatgaa caaaacacag agttaggtat gatttgtgga
      841 aagttagatc gccagtatta tagtgcaagt gcaatttctt ccattgtcat accaccaaaa
      901 tagggaggtg atttaatggc aaagtggaat gtcatattaa gtacaacaga accctataat
      961 tacgtgggga tgattcaagt tcgacaaggc aataaaaaca ctgaagttat ggaagctaca
     1021 attgtcgaaa atggtcttcc atatgattta tcagaatgta aggtatattt tgaatcagtt
     1081 gttggcggaa aatatccagt ccaattagaa acaagaattg tggatgctaa aaaagggaaa
     1141 atcaaatata tttttgataa atattccatg cagtgtttgc atcgacaaac agccaatttc
     1201 attatattta aaggagaaga cttgattgga acaactcaag acttctccta ttttgtcatc
     1261 aatgctgttt caaaaacaga aggagaaatg ggttcttatt ggcaatcaat tgaagattta
     1321 attgctgata tgacagattt tattaatgaa aataaaggcg attttacgga ctggatgaat
     1381 gaaaggaaag aagaatttga tcgctggaga gaagaacagg agaatagttt ccaagattgg
     1441 agagaaggac aagaatcaga ttatttgtca tggtttgaat caatcaagga tattttgaag
     1501 tctatcgatc caggtggagt aatgttagcc gaattaatgg atgcacgtgt tgatattcaa
     1561 ggagttcgtc atgcgtctat ttcagagcgc ttgctggcag atatggatta tctatatcag
     1621 aaattacgag caacactttt cacgattgaa tacggtgaga ttgaagtgac tgatattttg
     1681 caggatgatc tcttttcaga taatcacgaa gtcgaaaaag ttggaactgt agaatttcca
     1741 attgaagaag gagctttgat tattgcaact gttgatgatc caaaacagaa tgttttcact
     1801 cttgagaaag ttggggtgat ttgatggtta aagtaaagag aatgatggag actgatgaat
     1861 ctggtgttaa acgtcaattt atgccaatta cacatgtttc tgcagtttta ggcttagaaa
     1921 aaatgatatc aggacaatca aaagttcttt cggttaatgg taaatatggt gcagtcattt
     1981 taacgaaagc tgatttagga ttagagaatg caattactga actaccttat gcaagcgaga
     2041 caagcgatgg tattcttact gctgaaatgt ttcaaaagat cgtaaatgga gaaggtggaa
     2101 catatatttt gccgattgct actcctgaac aattaggagg tataaaagtt ggggaactct
     2161 tagaagttac tgaagaaggt gttttatctg caactaagca aacagacttc aatttctctg
     2221 aagaattaaa gggaaaatta gaatctctaa aaatattaaa agcaggtgca aatatatcaa
     2281 ttgcagaaga tggaacaatt agttctacag gtggtagtgg gactggtggt gttaatcagt
     2341 catatgtaga tcaaaaattc caag
//
LOCUS       DAPBAF010000117         2176 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.126, whole genome shotgun sequence.
ACCESSION   DAPBAF010000117 DAPBAF010000000
VERSION     DAPBAF010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2176)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2176)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2176
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.126"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(<1..828)
                     /locus_tag="RD451_002877"
     CDS             complement(<1..828)
                     /locus_tag="RD451_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HDT7568050.1"
                     /translation="MTYTHLTTDELVMIESYFKINQSVAKTAHFLNRSRQTIHKVYLF
                     FKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIR
                     CSARTIYRMFKKGLFNPSDLPMKGKRKPNGHQERRGKQAFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIENKLNHWFESVPKNLFK
                     SITFDCGKEFSNWKQISNANDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNS
                     "
     gene            1011..1862
                     /locus_tag="RD451_002878"
     CDS             1011..1862
                     /locus_tag="RD451_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7568051.1"
                     /translation="MKSDDWIEHTWLPLKRNSKRKKFWVLQLWPLGKLCSYGARLILD
                     LTVYSIGVFGTAYYLINDPNRIAASDIFTVLMTLIFVMLLSIFTQLVMQFTRQKLTAG
                     KLFKSLFDLIVVNAILATLIKQIEQSGRTTKGVKDFLLTFIHFVNGHMYLFEVGIILF
                     FVGYVSTKLIKRSIEKEIEIDLIPTLLGYEYNVDFGRYDELINTDIVHTSIHESTVKG
                     IRSILKNGQEMKAIDRRKEIYNFYEVEASLRYGIGKLWLDGSNIRQNKPYIFWNSSDL
                     ELPMKDK"
     gene            1883..2166
                     /locus_tag="RD451_002879"
                     /pseudo
     CDS             1883..2166
                     /locus_tag="RD451_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345737.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          722 a          351 c          406 g          697 t
ORIGIN      
        1 tgaattgaaa tccatagatt tcaataaacc atctctacgt aacaatccgt tagaattctc
       61 gtttaggcct ctttgagacg gcgttcctgg atcagcgaaa taaatggcaa tatcattggc
      121 attactgatc tgtttccaat ttgaaaattc ctttccacaa tcaaaagtga tggatttgaa
      181 tagatttttc ggtacagatt caaaccaatg atttaatttg ttttcaatat caatcgcttg
      241 tctaccacac ggtttcaatg tgatgataac ttttgataat cgctcaacta aggtaattac
      301 agcactttta tgtttcaaac ctacgatagt gtcaccttca aggtgaccaa actcatttga
      361 gaattggcta taatcttttt cacgttcatg aatagagcga cggaaagctt gttttccacg
      421 tctttcttga tgtccatttg gtttacgctt gcctttcatc ggtaagtcag aaggattaaa
      481 tagccccttt ttgaacatac gataaatggt acgagcagaa caacgaatag gaaacgctgc
      541 acgaccaaca atcacatcgg gtgtccatcc ttgaacaacc tttctttgaa tatattctga
      601 ttgttcctca ggtaaaacaa gcgggcgtct accacagttt gatttgtttt tcttatactg
      661 ttgatagtac tctaaggctg attttccttg cttgaagaac aggtatactt tatggatcgt
      721 ttgtcttgaa cgattcaaga aatgcgcagt tttcgcaaca gattgattta ttttgaaata
      781 agactctatc attacaagtt catccgttgt aagatgggta taggtcattt gtactcactc
      841 cttataattc tttggacgga actattttga gtgtagcaca aatgactttt ttagttgtct
      901 agcttaattt tacaatcggc gtacttaaaa aattggttca ttgagcaacc tatcgctgct
      961 aaagtagcaa aggaaaacgt taaaggaaag aatttaggga agaaatcgaa atgaaatcgg
     1021 acgactggat tgaacacacc tggcttcctc tgaaaagaaa tagcaaacga aagaaatttt
     1081 gggtattgca attatggcca ttaggaaaac tttgtagtta cggggcacga cttattcttg
     1141 atttaaccgt ttactcgatt ggagtatttg gaacggctta ttacttgata aatgatccca
     1201 ataggattgc agcatcagac atttttacag tgctaatgac gttgattttt gtcatgctat
     1261 tgtctatttt tactcaatta gtcatgcaat ttaccaggca aaaattaaca gcaggaaaac
     1321 ttttcaaaag cctattcgat ttaattgttg taaatgcaat tctagcgact ttaataaaac
     1381 aaattgaaca atctggaaga acaacaaaag gagtgaagga ttttttattg acgtttattc
     1441 actttgtaaa tggacacatg tatttgtttg aagtgggtat tattctcttt tttgtcgggt
     1501 atgtatccac gaaacttatt aaacgttcaa ttgaaaaaga aattgaaatt gacctgattc
     1561 cgacacttct tggttatgag tacaatgttg attttggaag atatgacgaa ttgatcaata
     1621 cggatatcgt tcacacgagt atccatgaat ctactgttaa gggcatcaga tctattttaa
     1681 aaaatggcca ggaaatgaaa gcaatagatc gaagaaaaga gatctacaat ttttatgaag
     1741 tcgaagcaag cctacgatat ggcatcggaa aattgtggtt agatggaagt aatattcgtc
     1801 aaaacaaacc atacattttt tggaacagta gtgatttaga acttccaatg aaagataaat
     1861 aattatggag aatcgtttga aaatgattcc tctatacagg attgtgctta tagttggcat
     1921 ggagttaaaa accttaaaga aggagcagtt attcaaagtg aaagaacgtc ataatcagtt
     1981 actatgtagt aaaacgggta cgatgaacat tgaataccga acagaatatt tagaattaac
     2041 gaatcaaact gattttttgt tgattcgaaa gcaacaagag caagaaaaaa attaatggct
     2101 acttatagcc aattgattga tgaatgggaa caattcaagg aatctaaaat tccagaacgt
     2161 ctctaaaagc ctttat
//
LOCUS       DAPBAF010000118         2120 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.127, whole genome shotgun sequence.
ACCESSION   DAPBAF010000118 DAPBAF010000000
VERSION     DAPBAF010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2120)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2120)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2120
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.127"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            173..691
                     /locus_tag="RD451_002880"
     CDS             173..691
                     /locus_tag="RD451_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbU family protein"
                     /protein_id="HDT7568052.1"
                     /translation="MDKFNRLTLINQFEILKALNPNEEKYYAEKIEILTEGYEYHYSE
                     IFENISDPLPEEDSRFVLDILNMYRDITFSKNKLKDINSIDNYYIQFKGFDFNSSTEF
                     KLALYAQFFIEKLNRFQEIVEDSDFNTFNSHKPMRGTYIKFLENYNDLKSTNNYQFGN
                     LSYEMISKVLSL"
     gene            698..1210
                     /locus_tag="RD451_002881"
     CDS             698..1210
                     /locus_tag="RD451_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7568053.1"
                     /translation="MKLNSINDLFAIIGVIANILFSCLNFRFTQKNKKNKLSIEQMKK
                     DIETDLKNDHKERRKIEEYTSLMEKCKATDAIFSFLRKSDEIITRENIDLENEISKLE
                     SIFSDINSLKYLIVEENSDSFLEFEKYLTDLIDNRNNELMRQNIARFLTKLVSEWKSI
                     ISQNMDKLRY"
     gene            1481..2104
                     /locus_tag="RD451_002882"
     CDS             1481..2104
                     /locus_tag="RD451_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDT7568054.1"
                     /translation="MYLAYLRVSSDDQSLARQHKLIENWSVKNNIAEDDLKIFEEKVS
                     GKNIENRPELQELISFIRERDTIIIPSLDRLARNSKDTKDLLQLFRSKGASIEILDLP
                     SFNGVTDPALRDLLTNLVIEVFSYVAENERKKIKERQKQGIEIAKKNGRYTGKKIQYH
                     ANATGKNKLIYDEIVDGLKKKETISKIAKNAGVTRKTVYRVKRDLGM"
BASE COUNT          835 a          259 c          344 g          682 t
ORIGIN      
        1 aaaaaaaata gagccgtctc aacttttggc gaggtagacg agctctaaag ctttatttac
       61 atgccatccg ctttgaacgg actacactgg gcatgtgaca gcatgccctt tcatttatat
      121 tatatctcat tcttttatat aatgaaagta aataaatcat ggaggataaa atatggataa
      181 atttaataga ttaacattaa taaatcagtt tgaaatttta aaagctttaa atcctaacga
      241 agaaaaatac tatgctgaaa aaatagaaat actaacagaa ggttacgaat atcactatag
      301 tgaaatattt gaaaatattt ctgatccatt gccagaagaa gattcgcggt ttgttctaga
      361 catattaaat atgtatagag atattacttt tagtaaaaat aaattaaaag atataaattc
      421 aattgataat tattatatac aatttaaagg ttttgacttt aatagctcta ccgaatttaa
      481 gttagcactt tatgcacaat tttttattga aaaattaaat aggtttcaag aaatagttga
      541 agatagtgat tttaacactt ttaatagcca taaaccgatg agaggtactt atataaaatt
      601 tctcgaaaat tataatgatt taaaatctac caataattat caatttggaa acttgtctta
      661 tgagatgata agtaaagttc taagtttgtg atgataaatg aaattaaata gtataaatga
      721 tttatttgct attataggtg ttattgctaa catacttttt tcgtgtttga attttagatt
      781 tactcaaaag aacaaaaaga acaaactcag tatagaacaa atgaaaaaag acattgaaac
      841 tgatttaaaa aatgaccata aagaaagaag aaaaattgaa gaatatactt ctttaatgga
      901 aaagtgtaaa gcaactgatg caatttttag ctttttaaga aaaagtgatg agataatcac
      961 acgtgaaaat atagatttag aaaatgagat tagtaaactt gaatctatct tttccgatat
     1021 aaattctctt aagtatttaa tcgtcgaaga aaattcggat agctttttag aatttgaaaa
     1081 atatctaaca gatcttatag ataatagaaa taatgaatta atgagacaaa acattgcaag
     1141 attccttact aaattagttt ctgaatggaa aagtattatt tctcaaaata tggataaatt
     1201 aagatattaa ggatgttagt tttaaaataa actaatgtcc ttatttttgt gttcacattt
     1261 ctgttaccta agaaatactt aaaggaggtg atgtagccag caacgactac aacttgaacc
     1321 cgctatctac agtttatttg ttgtttcttt tgggtatact ctaatggtac aaatccatat
     1381 ttgcttaaag cgttgatttt tcagcggttt ttctttattg caaagtgtac cctaagacct
     1441 gtatactaat agtaaataga ttggatagga atgatggcaa atgtatttag cttatttaag
     1501 agtttcttcc gacgatcaaa gtttagctcg gcaacataag ctaattgaaa attggtcagt
     1561 caaaaataat attgctgaag acgatttaaa aattttcgag gaaaaagtct ctggaaaaaa
     1621 tattgaaaac agaccagagc tgcaagagct tatttctttc atacgtgaac gagatacgat
     1681 tattattcct agtcttgatc gattagcaag aaatagtaaa gatacaaaag acttacttca
     1741 attgtttcgt agtaaaggtg cttctattga aatattagac ctaccgtcgt ttaatggggt
     1801 aactgaccct gcattaagag acttgctaac aaatttagtc atagaagtgt ttagctatgt
     1861 tgctgaaaac gaacggaaaa aaatcaaaga gcgtcaaaaa caaggcattg aaattgcaaa
     1921 gaaaaatggt cgttatactg gtaaaaagat tcaataccat gccaatgcaa caggaaaaaa
     1981 caaattgatt tacgatgaaa ttgttgatgg tctgaagaaa aaagaaacta tttctaaaat
     2041 agcaaagaac gcaggagtta caagaaaaac cgtttatcga gtaaaaagag atttaggaat
     2101 gtaatatgtt ccagttagaa
//
LOCUS       DAPBAF010000119         2084 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.130, whole genome shotgun sequence.
ACCESSION   DAPBAF010000119 DAPBAF010000000
VERSION     DAPBAF010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2084)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2084)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2084
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.130"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(<1..319)
                     /locus_tag="RD451_002883"
     CDS             complement(<1..319)
                     /locus_tag="RD451_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HDT7568055.1"
                     /translation="MDEKTELTVKYQNELNLVPLKNFNAKQMDLFFALCARMKDRGLK
                     KVRFSFEELKELSDYKMTATKAFVGDLEKLYKDMLNLTYRTEDEDSIRYFVLFTGFEI
                     NKTK"
     gene            972..1067
                     /locus_tag="RD451_002884"
     CDS             972..1067
                     /locus_tag="RD451_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HDT7568056.1"
                     /translation="MCFVFTNFICSLLVGLLSALFSYWLNNRNKK"
     gene            complement(1369..1614)
                     /locus_tag="RD451_002885"
     CDS             complement(1369..1614)
                     /locus_tag="RD451_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7568057.1"
                     /translation="MRLEKEKMEKFPYEYFQNLEKLEQAIQAIKFDLTDEKLLEYKNM
                     TPERKRSLEKLMQLVNEDGGISDAAFDAWSEFHGEYN"
BASE COUNT          677 a          380 c          344 g          683 t
ORIGIN      
        1 tttttgtttt attgatttca aaaccagtaa acaaaacaaa gtagcgaata gaatcctcat
       61 cttcagtacg gtaagtaaga ttaagcatat ctttatagag cttttctaaa tcaccgacaa
      121 aggcttttgt agcagtcatc ttataatcac ttaactcttt taattcctcg aaagaaaatc
      181 taactttttt caaaccacga tctttcatac gagcgcataa tgcaaaaaat aaatccatct
      241 gcttagcatt gaaatttttc agcggtacta aattcaattc attttgatat ttgactgtta
      301 attccgtttt ttcatccatt cctttcttcc ccccttacaa ataaataata acctttaaca
      361 accaactcgt aaataggttg gttgttatta tacaaaagga tattagtact cagataaaaa
      421 gttgttagta ctcagataaa aagttgttag tactcagata aaaagttgtt agtactcaga
      481 taaaaagttg ttagtaccct tctgtatccg ttgggagagt aaggctcaac tgccccctaa
      541 aaagggttct aaaaaatctt taaaaaataa ataaaataaa cgcgcgcgcg cgagcaaaat
      601 ttcccgccaa aaaatcaccc actttttaaa ataaacaggt tcgcgcatga tattaaactg
      661 ccaatctagc tccctatggt cgctgtaaga aggagtgatc gctacgctct cacattttac
      721 ttgcagcagt cgcctttagg ctccttcgcc aaaaataatt cattagggac tcctttgtgg
      781 cgtcctgaga gctcgtctaa gccgttctaa gacaagattc gataaaaact atgtccttcg
      841 ttctaaagcg ccttacaggc ggtcagggca agccctaaca accccaaggc aataaaaaac
      901 ttaggcttat ttttgctttt ttattgtata attgattgtc gcctatccga cagtcttgcg
      961 actggaagga ggtgtgtttc gtgttcacta actttatttg ctcccttctt gttgggcttt
     1021 taagcgcttt gttcagttac tggttgaata accgaaacaa gaagtaaaac ttaattaagg
     1081 cgactcagcc cacaaaaaaa gccccagaga atccgacctc tctggggctt tcgtgtgttt
     1141 cgtgttcact tatttgcaat caaattataa cagaaataaa tatttatttc aaaaatatcc
     1201 tacaaaagtc taaaatccgt aattatttct tatatgcaac atttacaaat aaagtcgctc
     1261 tgagagctcg tatttttcga tttaagacgt tttatttagt ttttggtgta tttcattggt
     1321 ccaagctaaa aaactcttag aagcgatttt agagccattt aaacccactt aattatattc
     1381 tccatgaaat tcgctccatg cgtcaaaagc tgcgtctgaa attccgccgt cttcgttcac
     1441 tagttgcatt aatttttcca acgatcgttt tctttcgggt gtcatatttt tatattccaa
     1501 caatttttcg tctgttaaat cgaacttgat tgcttgaatt gcttgctcta atttttctaa
     1561 gttttgaaaa tattcgtaag gaaatttttc cattttttct ttctccagtc tcacaatttt
     1621 tctagaaata aaatcacttc tttgccgtct atactctcaa aaaaaatgtc gtttgaaaaa
     1681 ctaaataaat ttttgatcgt gcatttttaa atttggttat cgattacacg tgcagcactc
     1741 ccccccgaat tttaaagagc ataaggaaac gtgggaacac tttttaaaaa aagtgttcca
     1801 ataggctgtg cctattacgt ttctcaaaaa taaatgtggg aacaaaatat ttaaaaatag
     1861 gatagtgaaa ggatagtgaa ggatagtaaa aggagggtag taggatagca aaaaggatag
     1921 gctccttttc gctatccttt ttaaattgga ggaattaata tggaagtaag aataagaaat
     1981 gtggatgaga aaatcgtaag agaaattgat cgaagatgtg acgaacggtt ctgttgcaaa
     2041 gttttaaatc tactatcaaa taaggtagaa taatagaaaa agat
//
LOCUS       DAPBAF010000120         1948 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.131, whole genome shotgun sequence.
ACCESSION   DAPBAF010000120 DAPBAF010000000
VERSION     DAPBAF010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1948)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1948)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1948
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.131"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            180..482
                     /locus_tag="RD451_002886"
     CDS             180..482
                     /locus_tag="RD451_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7568058.1"
                     /translation="MLMEGKTQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINL
                     YYSNKNYFKIPATKTRMKKDVYFLFDIVTDVPDARSDHRRYDYLKYTFVDPERYKD"
     gene            complement(998..1071)
                     /locus_tag="RD451_002887"
     tRNA            complement(998..1071)
                     /locus_tag="RD451_002887"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1035..1037),aa:Ile,seq:cat)
     gene            complement(1626..1940)
                     /locus_tag="RD451_002888"
     CDS             complement(1626..1940)
                     /locus_tag="RD451_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7568059.1"
                     /translation="MDFYSNFILIIAILLLLNIWFFDKSRNAGIGFRTKRSTSSEKKW
                     VYSQTIFYGGVISISLLSSTLYSFNVIDVSMSNFISIIGILISAIITQLLLVFEEKSK
                     NN"
BASE COUNT          708 a          290 c          301 g          649 t
ORIGIN      
        1 tttataaggg tttgagcatt ttttattttc gcagattttc gttaaatgaa tgaaaatggc
       61 attcaaaata gcattcaaaa agaacacttt ttaatatata tgttccatcc atattatcaa
      121 tgatattcct actttacaaa aagaacatta gttcgtatac tctttttgag gtgaacatta
      181 tgttgatgga aggaaaaaca caattatggt ttaaatttga tccttcgaat agatttgtca
      241 aagattttta taaggtgtgg gattcagaag ttttcttttt agcaatcgaa gatagcttat
      301 taatcaatct ctattactct aataagaact actttaaaat tccggcaaca aaaaccagaa
      361 tgaagaaaga tgtgtatttt ttgtttgata tcgtgactga tgtgccagac gcacggagcg
      421 atcatcggcg ttatgactat ttgaagtata ctttcgttga tccagaaagg tataaagatt
      481 aaagtaggct acctaaaaaa ggtagcccgg aacggatttt atcaccatac ttataaaagg
      541 gatatttttt aagttagtat taagattgtg taatatgatg atatctatat tttatagtat
      601 cagtgctata aaatcaaaaa taagtcacta attaactacc actccaatta taagtctttt
      661 tcccattatt ttttacagtt atatggtatg ctttttaatg gcttcaaata taaaagagtt
      721 taaagcgtaa cacacttatg gggaagtggt ttttggggaa cgctttaaac tcttctttat
      781 tattatctca caatataacc caaatgtctt tccatttaaa aatcaaagta aaacttttca
      841 aatatacaga agtataacta tgtgaaacat cctttcatta atccataaaa ggatacataa
      901 aaaagccact catttgagtg gcaatgaaga aaagctttag cttgtataat actcttcaaa
      961 aaattctaac acagaacgat tcaattggct acattaatgt accctgtagg actcgaacct
     1021 acgaccggac ggttatgagc cgtctgctct gaccaactga gctaagggta gtggttgttg
     1081 ccacataaag ccataaacaa tcaaccagta gaatgcgtgg caacaaacct gttatcgcat
     1141 atcttggagt gtgactattt atgagtgata gtgaagatat gcgtctccat atatgtatgg
     1201 ttgagacaga taaacatgta tgaaaaacgt tgttaaatca acgttttttt attttggtca
     1261 aggagagaaa agtagagaaa tacaaaattt tttgcattga ttttgcattc aaaaaaacat
     1321 tcaaacattt agaaatcccc aatacgtatt caggaaaatc tattttaagg tttacaaaaa
     1381 gaacttttgt tcgtacactc tttttgaggt gaacttttat gctgatggaa ggaaaaacac
     1441 aattatggtt taagcatgtt ccttcaaata agttttttaa ttataaactc tagagaaatt
     1501 aattcatcct aacataaaat aattgttcac tcaaaagttt ttctagaaca attaaaacag
     1561 caggcttcac attcgctata catttgtaag aagtaataat tcctgtacta aaaggcataa
     1621 ttgctttaat tattttttga cttctcttca aacacaagaa gtagttgtgt aataattgca
     1681 gaaataagga ttccaataat agatataaaa tttgacatgg aaacgtctat aacattaaaa
     1741 gaataaagtg ttgaagaaag taaactgatt gaaataaccc ctccgtaaaa aatagtctgt
     1801 gaatataccc actttttttc agaagacgta cttcgtttgg ttctaaaacc tatccctgca
     1861 tttctactct tatcaaaaaa ccaaatattt agaagtaata atattgctat tattaagata
     1921 aaattactgt aaaaatccaa aagctatc
//
LOCUS       DAPBAF010000121         1942 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.132, whole genome shotgun sequence.
ACCESSION   DAPBAF010000121 DAPBAF010000000
VERSION     DAPBAF010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1942)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1942)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1942
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.132"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            468..1640
                     /locus_tag="RD451_002889"
     CDS             468..1640
                     /locus_tag="RD451_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
                     /protein_id="HDT7568060.1"
                     /translation="MTQVHFTLKSEEIQSIIEYSVKDDVSKNILTTVFNQLMENQRTE
                     YIQAKEYERTENRQSQRNGYYERSFTTRVGTLELKVPRTRDGHFSPTVFERYQRNEKA
                     LMASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLEPMVNEWQNRLLSEKN
                     YPYLMTDVLYIKVREENRVLSKSCHIAIGITKDGDREIIGFMIQSGESEETWTTFFEY
                     LKERGLQGTELVISDAHKGLVSAIRKSFTNVSWQRCQVHFLRNIFTTIPKKNSKSFRE
                     AVKGIFKFTDINLAREAKNRLIHDYIDQPKYSKACASLDDGFEDAFQYTVQGNSHNRL
                     KSTNLIERLNQEVRRREKIIRIFPNQTSANRLIGAVLMDLHDEWIYSSRKYINFDK"
     gene            complement(1770..>1942)
                     /locus_tag="RD451_002890"
     CDS             complement(1770..>1942)
                     /locus_tag="RD451_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021424053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="aminoglycoside phosphotransferase APH(3')"
                     /protein_id="HDT7568061.1"
                     /translation="DILRMYGNIDIEKAKEYQDIVEEYYPIETIVYGIKNIKQEFIEN
                     GRKEIYKRTYKD"
BASE COUNT          675 a          358 c          306 g          603 t
ORIGIN      
        1 aaaaagttca aaagatcaag tgtgcgcttc gctcccactc ccctcgacgt tttagtagcc
       61 tttccctcac ttcgttcagt ccaagccaac taaaaagttt tcgggataca ttctccttct
      121 cttcctaata atcaattaaa attttaatct ttatatttct gctaatcact caggaaacag
      181 tacagaaaaa caaacacgta tcatagatat aaatgtaatg gcatagtgcg ggttttattt
      241 tcagcctgta tcatagctaa acaaatcgag ttgtgtgtcc gtttttgggc gttctgctag
      301 cttgtttaaa gtctcttgaa tgaatgtatg ttctaagtca aaaaactctg acagcgcctt
      361 tatatagata aagtccgtat aattgtgtaa aagtaaaaag gccatataac agtcctttta
      421 cggtacaatg tttttaacga caaaaacata cccaggagga cttttacatg acccaagtac
      481 attttacact gaaaagcgaa gagattcaaa gcattattga atattctgta aaggatgacg
      541 tttctaaaaa tattttaaca acggtattta atcaactaat ggaaaatcaa cgaacagaat
      601 atattcaagc aaaagaatat gaacgaacag aaaaccgaca aagtcaacga aatggctatt
      661 atgagcgcag ctttacgaca cgtgtaggca cgctagaatt aaaagtaccc agaacacgtg
      721 atggccattt ttcacccaca gtgtttgaac gttatcaacg aaacgaaaaa gccctcatgg
      781 cttcaatgtt ggaaatgtat gtatcaggcg tttcaactcg taaagtatca aaaattgtgg
      841 aagaactttg tggtaaatcc gtctctaagt ccttcgtttc tagcttaaca gaacagctag
      901 aacctatggt taacgagtgg cagaatcgtt tattatcaga aaaaaattat ccttacttaa
      961 tgaccgatgt actctatata aaagtacgag aagaaaatcg agtactctca aaaagctgtc
     1021 atatagcgat tggaataacc aaagatggcg accgtgaaat tatcggcttc atgattcaaa
     1081 gtggcgaaag cgaagagacc tggacaacat tttttgaata cctaaaagaa cgcggtttac
     1141 aaggtacgga actcgttatt tctgatgcgc acaaaggatt agtctctgcc attagaaaat
     1201 ccttcaccaa cgtaagttgg caaagatgcc aagttcactt cctaagaaat atctttacca
     1261 ccattcctaa aaaaaattca aaatctttca gagaagctgt taaaggaatt tttaagttca
     1321 cagatattaa cttagcgcgt gaggctaaaa atcgattgat tcatgattat atcgatcaac
     1381 caaaatattc aaaagcttgc gcatcattgg atgatggatt cgaagacgcc tttcaatata
     1441 ccgtacaagg aaattcccac aatcgactaa agagtaccaa tctaattgaa cgactgaatc
     1501 aagaagtacg cagaagagaa aagattattc gcatcttccc caatcaaaca tcagccaatc
     1561 gcttaattgg agccgttctt atggacctac atgatgaatg gatttattct tcaagaaaat
     1621 acatcaattt tgataagtag aaatggtaaa aacattgtat agcattttac acaggagtct
     1681 ggacttgact cacttccttt attatttttc atttttttaa actatttaat actaatgtct
     1741 tttataatag cttttcatat attatataat caatctttat aagtcctttt ataaatttct
     1801 tttctaccat tttcgataaa ttcctgttta atatttttaa ttccataaac aatagtttca
     1861 ataggataat attcttcaac tatatcttga tattcttttg ctttctcaat atctatattt
     1921 ccatacattc ttaatatatc tt
//
LOCUS       DAPBAF010000122         1923 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.133, whole genome shotgun sequence.
ACCESSION   DAPBAF010000122 DAPBAF010000000
VERSION     DAPBAF010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1923)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1923)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1923
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.133"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(286..1218)
                     /locus_tag="RD451_002891"
     CDS             complement(286..1218)
                     /locus_tag="RD451_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDT7568062.1"
                     /translation="MRKEDLMMKFRKNQNKEKQIPKEKKPRVYKVNPHKKVVIALWVL
                     LGLSFSFAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWEQSDKSI
                     DNRMESLKGYLTDELQALNVDTVRKDIPVSSSVRGFQIWTVEPTGDNEFNVTYSVDQL
                     ITEGENTKTVHSAYIVSVYVDGSGNMVLVKNPTITNIPKKSSYKPKAIESEGTVDSIT
                     TNEINEFLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIHNRKDNQVTV
                     SLTVEYIDQQTKATQVSQFDLVLEKNGSNWKIVK"
     gene            complement(1215..>1923)
                     /locus_tag="RD451_002892"
     CDS             complement(1215..>1923)
                     /locus_tag="RD451_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HDT7568063.1"
                     /translation="PNSLSTEESIKQGVKYFSELLASSERLSVDLESVIQSYNYGGGF
                     LGYVANRGNKYTFELAQSFSKEYSGGEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQ
                     YLVTTEFDDDTVQAIMDEALKYEGWRYVYGGASPTTSFDCSGLTQWTYGKAGINLPRT
                     AQQQYDVTQHIPLSEAQAGDLVFFHSTYNAGSYITHVGIYLGNNRMFHAGDPIGYADL
                     TSPYWQQHLVGAGRIKQ"
BASE COUNT          547 a          396 c          341 g          639 t
ORIGIN      
        1 atacaaagca tacagatatt ctctggatac tttagaatca catgataaag gtattcttaa
       61 actgggtaca aaaaactaag ccctcctaaa aaaggacatc taattatttg ttcctgctat
      121 caaattgaca gtttatttaa gaataccttg ccgcatattt attaactcct tttaaatagt
      181 cacttaaata atagcacgta agagcatatt tgtaaaggaa tctccaattt tttatcaaaa
      241 agagtacatg attacaaagt atctgtaatc atgtaccaat atttgttatt ttacaatctt
      301 ccaattactc ccgttctttt caagtaccaa atcaaattga gatacctgcg ttgctttggt
      361 ctgctggtcg atatactcca ctgtcagcga taccgtgact tgattatcct tacgattgtg
      421 aataggattt accagttctt gaaagatgta ctcttttccg attggtttta atatcccgtc
      481 attcacatag taggaaagtt cactggctgt cgctgtagga tagagcttga agaacgtcgt
      541 taaaaactca ttgatttcat tggttgtaat ggaatcaacc gtcccctcac tttcaatggc
      601 ttttggttta taacttgatt tcttaggtat gttggtaatg gtcggattct taaccagtac
      661 catatttcca gaaccatcta catagacact cactatataa gcagagtgga cggtctttgt
      721 attttctccc tctgtaatga gctggtctac actgtaggtt acattaaact cattgtcgcc
      781 agttggctct accgtccata tctgaaatcc tcttacagaa gacgatacag gaatatcttt
      841 gcgtactgta tcaacattga gagcttgaag ttcatctgtc agatagcctt ttagactttc
      901 cattcgatta tcaatggact tatcggattg ctcccatgaa tagtagactt tcgcaaagtt
      961 ctctacaaaa ttttctacat gatgagtatc aacgtattcc ttttctatga tagttgtttc
     1021 gtgaatagta tgagtatcta tagctgtaaa gtgcttgaat atcgcaaagc tgaaactaag
     1081 ccctaaaagt acccacaagg caatcacaac ctttttatga ggattgacct tatagacacg
     1141 aggtttcttt tcctttggta tctgtttttc tttattctga ttttttctaa atttcatcat
     1201 taaatcttcc tttctcattg tttgattcgt cctgctccca ctaaatgctg ttgccagtag
     1261 gggcttgtta agtcggcata accgattggg tcgcctgcat gaaacatacg gttattgcca
     1321 aggtatatcc caacatgagt aatataagag ccagcgttat aggtagaatg aaagaaaacc
     1381 aaatcgccag cttgtgcttc cgatagtggg atatgctggg tcacatcata ttgctgttgt
     1441 gcggttcgtg gtaagttaat tccagctttt ccatacgtcc attgtgtcag tccgctacaa
     1501 tcaaaagaag tagtcgggga agctccaccg taaacgtatc gccagccctc atatttcagt
     1561 gcttcgtcca tgatggcttg taccgtatca tcatcaaact ctgttgtgac aagatactgc
     1621 gttaccagtt gcacataaaa catattgcca tagttgtatc gccagccccc attgataggt
     1681 atggctatgg gattggggta agacactttt tcgccacctg aatactcttt tgagaaactt
     1741 tgagccagtt caaaggtata tttatttcca cgattagcca cataccctaa gaaaccacca
     1801 ccataattgt aggactggat aaccgattct aaatctacac tgagcctttc gctactggct
     1861 aataattcac tgaaatactt cacaccttgc ttaatggatt cttctgtact caatgaatta
     1921 ggt
//
LOCUS       DAPBAF010000123         1914 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.134, whole genome shotgun sequence.
ACCESSION   DAPBAF010000123 DAPBAF010000000
VERSION     DAPBAF010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1914)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1914)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1914
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.134"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            100..570
                     /locus_tag="RD451_002893"
     CDS             100..570
                     /locus_tag="RD451_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HDT7568064.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLGANKAIISELTV
                     GGLVDSLALAEGFIGEDIYEMFSEIRQLKKGENCIEVHHESPNVRFKRGDNEMIFNNH
                     VSDHTELYGIVNQILTELFGLGPYAFKEENGNPKLNEEWQETIEIQRNNPHLFQ"
     gene            792..1895
                     /locus_tag="RD451_002894"
     CDS             792..1895
                     /locus_tag="RD451_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HDT7568065.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHQLIIPHVLRDVELPDTTTHFDKETLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDDGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
BASE COUNT          646 a          315 c          442 g          511 t
ORIGIN      
        1 gaatctctga agaataaatc acgtgatcgt gacgataaaa tacacttacg tcaggtgata
       61 aaaaatacat aagtagaaaa ctaagaggag gaacagaaaa tgaaagaagt tcaattgatc
      121 agaaaaagcg aactatcaga aggtggttgc aatgcatgcg gcgtagtaga agcaacaagc
      181 tatacattaa agcttggtgc caacaaagcg ataatctctg agttgacagt aggcggtctt
      241 gtggacagtc tggcgcttgc tgaaggtttt attggagaag atatttatga gatgttttca
      301 gaaatccgtc agttaaaaaa aggggaaaac tgcatagagg ttcatcatga gagcccgaat
      361 gtgagattca aacgtggtga taatgagatg atcttcaata atcatgtgtc cgatcacacc
      421 gagctatatg gaatcgtgaa tcaaatacta actgagcttt ttggattggg accttatgcg
      481 ttcaaggaag aaaacggtaa tccaaaatta aacgaagaat ggcaagaaac gattgaaata
      541 caaagaaaca acccgcactt atttcaatag gcatccacag tatttcgtaa aagggacttt
      601 gacacgactt ttgtcaaaat cccatcgttt tttatctatt tgtgttctaa acatttcttt
      661 cagagtagta acaactggaa tgactgaaat gtaaacagat tatttgcctg tatcaatacg
      721 gaagagtaat ataaagtgtg taaacgctat catattattc attcaatttt ttatagaggg
      781 aaggcattga aatggaaaaa acgtatcaag caggtacaaa tgaaggaata gtggatttta
      841 tcaatatgga agatttagaa atagccgctt cacaagtgat tccagctggt ggttatggtt
      901 acatcagcag tggtgctggc gacttattta cttatcaaga aaatgaacgg gcattcaatc
      961 atcagctgat tattcctcat gtattaagag atgtagaatt acccgataca actacacatt
     1021 ttgacaaaga aacgctgact gcaccaatca tcatggcacc agttgctgct catggcttag
     1081 ctcatgtgaa ggcggagaaa gcttctgcaa aaggtgtagc agattttggg acgatctata
     1141 cagcaagttc ttacgcttct tgtacattag aagagataag agaagcaggc ggggagaaag
     1201 caccgcaatg gtttcaattt tatatgagca aagatgatgg gatcaatttg gatattcttg
     1261 aagtggccaa gcgtaatgga gcaaaagcaa tcgtattgac agcggatgca acagttggcg
     1321 gaaaccgtga aacagaccgc agaaatgggt ttaccttccc actgccaatg ccgatcgttc
     1381 aggcttatca atcaggagta ggccaaacga tggatgctgt gtacaaatct tccaaacaga
     1441 agcttagtcc aaaagatgta gaatttattg ctgctcattc tgatttgcca gtctatgtga
     1501 aaggtgtcca gtcagaagaa gatgtctatc gttcattaga atctggtgct ggcggaatct
     1561 gggtatctaa tcatggtggc cgtcaactag atggtggtcc agcagcgttt gattcgttgc
     1621 aatatgtggc agaagcagta gataaacgtg taccaatcgt gtttgacagc ggtgtacgac
     1681 gcggacagca tgttttcaaa gcaatcgcat caggtgcaga tcttgttgct attggcagac
     1741 ccgttattta tggattgtct ttaggaggaa gtacaggagt ccatcaagtg tttgatttct
     1801 ttaaaacaga attggaaatg gtcatgcaat tagctggaac acaaacagta gaagatatca
     1861 aaaaaataaa attgcgtgag aatcgtttta tttaagaaac aaatgacgaa aaaa
//
LOCUS       DAPBAF010000124         1887 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.135, whole genome shotgun sequence.
ACCESSION   DAPBAF010000124 DAPBAF010000000
VERSION     DAPBAF010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1887)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1887)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1887
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.135"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            164..715
                     /locus_tag="RD451_002895"
     CDS             164..715
                     /locus_tag="RD451_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF334 domain-containing protein"
                     /protein_id="HDT7568066.1"
                     /translation="MKRLEASTSNFNNKLDVFEEKTKHARLNFETTAKHYIKRLDEDN
                     LKLDFQQAIQDELSDTKDEIREVTKQAREETKEYKEILESKIKDHNKVVDKSNTALKV
                     MTKGVTNIFFVLIIFVLVMLVTGPIGHFFGIEHLYSFINGFIDDHESAWRYLMLILYA
                     VPYVFFAIILWLIALFFRVFNDL"
     gene            1173..1853
                     /locus_tag="RD451_002896"
     CDS             1173..1853
                     /locus_tag="RD451_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element ISS1N family transposase"
                     /protein_id="HDT7568067.1"
                     /translation="MNHFKGKQFKKDVIIVAVGYYLRYNLSYREVQELLYDRGINVCH
                     TTIYRWVQEYSKVLYYLWKKKNRQSFYSWKMDETYIKIKGRWHYLYRAIDADGLTLDI
                     WLRKKRDTQAAYAFLKRLHKQFGEPKAIVTDKAPSLGSAFRKLQSVGLYTKTEHRTVK
                     YLNNLIEQDHRPIKRRNKFYQSLRTASSTIKGMETIRGIYKKNRRNGTLFGFSVSTEI
                     KVLMGITA"
BASE COUNT          678 a          291 c          377 g          541 t
ORIGIN      
        1 aaagaaggca ctctcttcgg gttttcggtc tgtactgaaa tcaaggtatt attgggaatc
       61 ccagcttaaa tcatagatac cgtaagggat tttattcttt atttaaaact ttgcaacaga
      121 accgaagagc gagcaagaca ggaacgagag aacaaacata ctcatgaaaa gactagaggc
      181 ttcgacctcg aactttaata ataagttaga tgtttttgaa gaaaagacta agcatgcaag
      241 attaaacttt gaaacaactg caaagcacta tattaaacga cttgatgaag ataatttgaa
      301 attagatttt caacaagcta ttcaagatga attaagcgat actaaagacg aaatacgtga
      361 agtgacgaaa caagcgagag aagaaacaaa agagtataaa gaaatcttag aaagtaaaat
      421 aaaagaccat aacaaagtgg ttgataaatc gaatacagcg ctaaaagtga tgacaaaagg
      481 cgttacaaat atattttttg tgctaattat ttttgtactt gtaatgcttg tgacaggtcc
      541 gataggtcat ttctttggta ttgaacattt atatagcttt attaatggtt ttattgatga
      601 ccacgaaagt gcatggcgat atttgatgtt gatactttat gcagtaccct atgtattctt
      661 cgctatcatt ctgtggctca tagcattgtt ttttagagta tttaatgacc tttaggtaga
      721 tttatatata aaaagggcta aatacgcaaa ataccccctt aaaatgcaaa ataaatgcaa
      781 ataagggggt aactccttat gaaaaaacaa ctaatagtat tataacacgt ttttatgccg
      841 agaaaactta ttggttggaa tgggctatgt gttagctaac ttgttagcga gttggttgga
      901 cttgaattgg gattaatccc aagaaagtac caactcaaca acacataaag ccctgtaggt
      961 tccgaccaat aaggaaattg gaataaagca acgaaaggag ttgagtaaaa tgagtgagaa
     1021 aacgaagaaa atcattcgag tatcattagc tttttcacaa gtagtagtgc aatcattgat
     1081 agtttattat acttaccagg gttctgttgc aaagttttcc aaaaaatcta ttttagtgta
     1141 aaattgagaa aaaagacaga gaggacagag taatgaatca ttttaaaggc aaacaattca
     1201 aaaaagacgt cattattgtc gctgttggtt actacctgcg ttacaatcta agctatcgtg
     1261 aagttcagga attgttatat gatcgtggaa taaatgtttg tcatactacg atttatcgtt
     1321 gggtgcaaga gtacagcaaa gtcctctatt atctttggaa gaagaaaaat agacaatcct
     1381 tctattcatg gaaaatggac gaaacctata tcaaaattaa gggacgttgg cattatcttt
     1441 atcgtgcaat tgatgcggac ggcttaacct tagatatctg gttacgaaag aaacgggata
     1501 cgcaagcagc ctatgctttc ttaaaacgac tccataaaca gtttggtgag ccgaaagcaa
     1561 ttgtgaccga taaagcacct tctcttggct ccgcctttag aaagttacag agtgtgggtt
     1621 tatatactaa gacagagcac cgaactgtga agtatcttaa caatttaata gaacaagacc
     1681 atcgacctat taaacgacga aataaatttt atcaaagtct ccgtacagcc tcttccacga
     1741 ttaagggcat ggagaccatt cgaggaatat ataaaaagaa ccgaagaaat ggaacgctct
     1801 tcggcttttc ggtgtctact gaaatcaagg tattaatggg aataacagcc taagatattt
     1861 ggagttcaga gagggcgcgt ttgattt
//
LOCUS       DAPBAF010000125         1867 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.136, whole genome shotgun sequence.
ACCESSION   DAPBAF010000125 DAPBAF010000000
VERSION     DAPBAF010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1867)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1867)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1867
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.136"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            87..160
                     /locus_tag="RD451_002897"
     tRNA            87..160
                     /locus_tag="RD451_002897"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:121..123,aa:Ile,seq:cat)
     gene            complement(675..974)
                     /locus_tag="RD451_002898"
     CDS             complement(675..974)
                     /locus_tag="RD451_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7568068.1"
                     /translation="MLFNETQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINLY
                     YSNKNYFKIPAAKTRMKKDVYFLFDIVTDVLDARSDHRRYDYIKYTFVDPERYKD"
     gene            complement(980..1210)
                     /locus_tag="RD451_002899"
     CDS             complement(980..1210)
                     /locus_tag="RD451_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7568069.1"
                     /translation="MMEEFIRKNISDEYADFYEQSNEKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETKFKNRSE"
     gene            complement(1460..1660)
                     /locus_tag="RD451_002900"
     CDS             complement(1460..1660)
                     /locus_tag="RD451_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDT7568070.1"
                     /translation="MKINYTVDLVSFSLVINFSLFSLRLFIDGLRHTHASILLYQGVN
                     ILSVSKRLGHSSLETTMSTYTK"
BASE COUNT          632 a          304 c          291 g          640 t
ORIGIN      
        1 tagtcacact ccaagctatg cgataacagg tttgttgcca cacattctac tggttgattg
       61 tttatggctt tatgtggcaa caaccagtac ccttagctca gttggtcaga gcagacggct
      121 cataaccgtc cggtcgtagg ttcgagtcct acagggtaca ttaacgtagc catttgaatc
      181 gttctgtgtt agaatttttt gaagagtatt atacaagcta aagcttttct tcattgccac
      241 tcaaatgagt ggctttttta tgtatccttt tatggattaa tgaaaggatg tttcacatag
      301 ttatatttct gtatatttga aaagttttac tttgattttt aaatagaaag acatttgggt
      361 tatattgtga gataataata aagaagagtt taaagcgttc cccaaaaacc actgccccat
      421 aagtgtgtta cgctttaaac tcttttatat ttgaagccat taaaaagcat accatatttt
      481 tgaaaaaaag tgagaaaaaa ggcttataat tggagtggta gttaattagt gacttatttt
      541 tgattttata gcactgatac tataaaatat agatatcatc atattacaca atcttaatac
      601 taacttaaaa aatatctcct ttcataagta tggtgataaa atccgttccg ggctaccttt
      661 ttaggtagcc tactttaatc tttgtatctt tctggatcaa cgaaagtata ctttatatag
      721 tcataacgcc gatgatcgct tcgagcgtct agcacatcag tcacgatatc aaacaaaaaa
      781 tatacgtctt tcttcattct agttttcgca gcagggattt taaagtagtt cttattagaa
      841 tagtagagat taattaataa gctatcttcg attgctaaaa agaaaacttc tgaatcccac
      901 accttataaa aatctttgac aaatctattc gaaggatcaa atttaaacca taattgcgtc
      961 tcattaaaaa gcataaccat tactccgatc tatttttaaa cttagtctct acctctaata
     1021 tatatcgagt ttttattttg ccttcagaga atactgtttc tttttttgca gttacaggtt
     1081 gtttattttc ggaaaaagct aatatagcta aaattgaaac atccatctgg aatttgtctt
     1141 tttcgttgct ttgctcataa aaatctgcat attcatcact aatatttttt ctaataaatt
     1201 cttccatcat aaagatcacc tcgaaaagag tatacgaaca aacgttcttt ttgtaaaggt
     1261 ggaatttatt atactaaata aataggtgaa caagtacttg tgccaaatta tgtgccaaaa
     1321 aaaatcgaat ttaataaaac acaaacaaaa agaaatccta ttatgataac atttcttata
     1381 ataacaaaca caacagaaga cgtgtaatag ttagtcagga acgtacaaat aacccctgta
     1441 tcctttgcgg tacagggggt tattttgtat aagtagacat tgtagtttct aaactgctat
     1501 gtcctaaacg tttcgatacg ctaagtatat ttactccttg ataaagtaaa atagatgcat
     1561 gcgtatgtct tagtccatca ataaacagtc gaagagaaaa tagggaaaaa ttgattacta
     1621 aagaaaaact tactaggtcg acggtgtagt tgattttcat acttcaatag attcgaatta
     1681 aacgatttcg attggcttat accagtccta tccaacgaaa gatatatcgt tcttaactct
     1741 agcggtataa cttgaagctt tacgtaaagc caatgggaat gaactggaga tgacttttta
     1801 ttatttttag taatagctga tgggttaata cttacaactt tccttttcaa agtaccatat
     1861 aaaaaaa
//
LOCUS       DAPBAF010000126         1852 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.137, whole genome shotgun sequence.
ACCESSION   DAPBAF010000126 DAPBAF010000000
VERSION     DAPBAF010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1852)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1852)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1852
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.137"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(49..558)
                     /locus_tag="RD451_002901"
     CDS             complement(49..558)
                     /locus_tag="RD451_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HDT7568071.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(670..1668)
                     /locus_tag="RD451_002902"
     CDS             complement(670..1668)
                     /locus_tag="RD451_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDT7568072.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     VIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
BASE COUNT          560 a          351 c          332 g          609 t
ORIGIN      
        1 aaagaaagaa ctcgtctaaa tagacgtttt ctttcttttt ttgttgaatt attgagtaag
       61 gcgacttctt ttttctggtt ctttgtgtgc taatcgactg gcagcagcag cggcgatcgc
      121 tccgacgata tcatctaaga aggtatggac atgaacgcca tcgtggctgt ttagttcttt
      181 taaaatacca ggtttcacct tgtcgatata accataattc gtaaagccga tcgtaccgta
      241 aacattcacg attgacaagg ctaggatctc atcgataccg taaaggcctt cgtcatcttc
      301 gataatatgt tgcaacggac tcatcaattt tttcttttct gctaatatat ctaattggat
      361 tccagtgata atggcgttat gtacttcacg ctttgttagc acgctgttga cactttcagt
      421 acaatccgcc aaagtcaaat cagaaatata gtctttttgt aaaaacatga caagttgtgc
      481 gatatcttct acagttacgc cacgttcctt caatagttct cttgcctttt cttctaaagt
      541 ctcagttttg acgaccatat tattgctccc cctttatttt ttctttctct atttcatgtt
      601 aacggaacat gaaaaaaatg caagaaactg ctttcgggtt taacttgaaa tgcaaagaga
      661 tataaaaaat caactaggac gaagattttt atcgtataag cttgtgctgt gaccaggctg
      721 agttcgttcc tttggattaa tatagtgtaa agcgttgttc actgcagtag gtgcttcacc
      781 gagcccagta gcaatcagtt tcacttttcc ttcataggta cagatgtcac cagctgcata
      841 aacgcctgga atagaagtag acatatctga ttttacagta atggcatttc tggtactatc
      901 aagtccccaa gaagaaagat gttctaaatt agaagagaat ccataattga cgatcagaga
      961 atcaatcatc aaatcaatcg tctcgtcact tttcactttt tttaaccgga tatctgtcag
     1021 ttccccatta ttgcctgata atccatcgat gagataggga gtaagcaagt tgacagatga
     1081 agatttcaag cgtgatacac tatgttcgtg cgcacgaaat tccgggcgac gatgaatcaa
     1141 gtaaacttcg cttgcaatag gctctaacat caacgtccaa tcgatagcag aatcaccacc
     1201 tccagcaata gcgacttttt ttccagcata cttcatcaaa tcattcacga aataatccaa
     1261 tccgtggttt tcaaatgatt cagcattatc taaattcaat tttcttggct ggaatgaacc
     1321 atttcctaaa gctaaaatga ctgctttgga ataatggatg actttatttg tagtaatctc
     1381 gataacttcg tcttcacgag taagcgagag aacttcttct tttaaatgga atgtatggtt
     1441 aaaagtagtt aattgttttt ctaattgatc gattaattca cttgctttta ttgctggata
     1501 cccaggaata tcgtaaatat atttttcggg atacaaagtt gctaattgac caccaagttg
     1561 aggtagactg tcaatgattt ttgttttagc ttggcgcatt cctgcgtaaa aagcggcaaa
     1621 catccctaca ggacctgcac cgatgattgt aatgtcatag atttccataa aaattcctcc
     1681 cttttcacac tatagcagaa tttaattgag aatgcttctc aaaaatgttt gaattcgaaa
     1741 tcgaaacggt aagttataga atgtatctag tgatgaaaaa taaaagaaaa caaatctagt
     1801 atttttacga gaggttaggt attatgttat tattattatg aagtatgcaa at
//
LOCUS       DAPBAF010000127         1636 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.138, whole genome shotgun sequence.
ACCESSION   DAPBAF010000127 DAPBAF010000000
VERSION     DAPBAF010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1636)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1636)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1636
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.138"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(183..1502)
                     /locus_tag="RD451_002903"
     CDS             complement(183..1502)
                     /locus_tag="RD451_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element IS1678 family transposase"
                     /protein_id="HDT7568073.1"
                     /translation="MTSLHKNQVKFNSNITISHTGGQLSSDSGLVLVKELMNIFGFSE
                     LAKQHIHIEDERAYFTHDNLSILEQFIMQLIAGYSADSAANLLRQDPVFKAVLDRKEL
                     ASQSSLSRFLDRLSEENIHELQALNQELIDKARLIRNDTELIIDLDSTHSDTFGHQEQ
                     TNYNTHYQTYGYHPLVAFDGLTGDFLKAELRSGNQYTSKGVKEFLTPLLEHYNHSLPN
                     TDILVRGDSGFATPGVYDSCESKKSHYVIRLKNNRRLGQIAEKSVLYGDNQKWEEREV
                     QYFSTTYQAQSWSQSRRVCIRSTREAGELLFRHEFIVTNLSENVSPDTIFSIYAKRGT
                     MENFIKEAKAGFYFDKTDSPRFLENHVRMMLSLIAYNLVNFLRTIGFEEVQKGMTIHS
                     IRLKFLKVAGKLVQTGRRVYLKLSSYHVYQNEFYRVFARLRRASQWI"
BASE COUNT          485 a          301 c          325 g          525 t
ORIGIN      
        1 attctttggc acattttatt gaaatatgta tcactaatat ccctatcaac tgattttgac
       61 taaaaagtta cttcaaacat tcactgttca aaaatattga ggaataaatt ttgggtgtaa
      121 ggcattttga gcatacttct ccctggataa cttcccagta aaaaaatcgt tagattgttg
      181 gattagatcc attgactggc tcgcctcagg cgagcaaaga ccctgtagaa ttcattctga
      241 tacacatgat aactagataa tttgagatag actcgtctac ccgtttggac taatttccca
      301 gcaactttca gaaacttcaa tcgaatagaa tgaatggtca ttcccttttg gacttcttca
      361 aagccaatcg ttcttaagaa gttgactaag ttgtaagcta tcaagctgag catcattcgg
      421 acatgattct ccaaaaagcg aggactgtct gttttgtcaa agtaaaagcc agctttcgct
      481 tctttaatga agttctccat tgtgccacgt ttggcataga tagaaaagat ggtatcagga
      541 gaaacatttt ctgatagatt cgtcacgata aattcatgtc gaaagagtag ttcgcccgct
      601 tcacgtgttg agcgtataca cacgcgacga ctttgtgacc aggattgtgc ttgataagtg
      661 gtcgagaagt actgaacttc tcgttcttcc cacttttgat tatcgccata aagtactgat
      721 ttctcagcta tttgacctag tctacgatta ttcttcagtc gaataacata atgactcttt
      781 tttgattcac acgaatcata cacaccaggt gtagcgaacc cgctgtctcc acgaaccaag
      841 atgtcagtgt ttggtagaga gtgattatag tgctctaata aaggtgtgag aaactccttt
      901 acgccttttg atgtatattg atttcctgaa cgtagttcag cttttaagaa gtcaccagtc
      961 aatccgtcaa aagctaccaa tggatggtaa ccataggttt ggtagtgtgt attataattc
     1021 gtttgttctt ggtgaccaaa tgtatctgaa tgggtcgaat ctaaatcaat gattaattcc
     1081 gtatcattac ggatgaggcg tgctttatcg ataagttctt ggttcaaagc ttgaagttca
     1141 tggatattct cctcagatag tcgatctaaa aatcgggaaa gtgaagattg agaagcgagt
     1201 tctttcctat ctaaaacagc tttaaacaca ggatcttgtc tcaggagatt agctgcagaa
     1261 tcagctgagt aaccagcaat taattgcata atgaactgct caagtatgga taagttgtca
     1321 tgagtaaaat acgctcgttc gtcttcaatg tgaatgtgtt gcttagccag ttcagaaaaa
     1381 ccaaagatgt tcatcagctc tttcactagg acgagacccg aatcactcga taattgacca
     1441 cctgtatgag aaatagtgat atttgaattg aattttactt ggtttttgtg taagctagtc
     1501 atgaaaagaa ctcctttctt ttggttggtt tagtcacttt aaccatagca gaaaggggtt
     1561 cttttttcat cacttaacgg gtgaagatga aaaagtaatt gtaagctgcc gtgaggcagt
     1621 ttcacatggt tttaat
//
LOCUS       DAPBAF010000128         1536 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.139, whole genome shotgun sequence.
ACCESSION   DAPBAF010000128 DAPBAF010000000
VERSION     DAPBAF010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1536)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1536)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1536
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.139"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(<1..>1536)
                     /locus_tag="RD451_002904"
     rRNA            complement(<1..>1536)
                     /locus_tag="RD451_002904"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          321 a          476 c          337 g          402 t
ORIGIN      
        1 gggaaatctc atcttgaggt gggcttcaca cttagatgct ttcagcgttt atcccttccc
       61 tacatagcta cccagcaatg cccttggcag aacaactggt acaccagcgg taagtccatc
      121 ccggtcctct cgtactaagg acagctcctc tcaaatttcc aacgcccgcg acggataggg
      181 accgaactgt ctcacgacgt tctgaaccca gctcgcgtgc cgctttaatg ggcgaacagc
      241 ccaacccttg ggaccgacta cagccccagg atgcgacgag ccgacatcga ggtgccaaac
      301 ctccccgtcg atgtggactc ttgggggaga taagcctgtt atccccaggg tagcttttat
      361 ccgttgagcg atggcccttc catgcggaac caccggatca ctaagcccga ctttcgtccc
      421 tgctcgactt gttggtctcg cagtcaagct cccttctgcc tttacactct tcgaatgatt
      481 tccaaccatt ctgagggaac ctttgggcgc ctccgttacc ttttaggagg cgaccgcccc
      541 agtcaaactg cccatctgac actgtctccc accacgatta gtggtgcggg ttagagtggc
      601 cataacgcag gggtagtatc ccaccagcgc ctccatcgaa actagcgttc cgatttctac
      661 ggctcctacc tatcctgtac atgcggtaca gacactcaat atcaaactac agtaaagctc
      721 catggggtct ttccgtcctg tcgcgggtaa cctgcatctt cacaggtact aaaatttcac
      781 cgagtctctc gttgagacag tgcccaaatc gttacgcctt tcgtgcgggt cggaacttac
      841 ccgacaagga atttcgctac cttaggaccg ttatagttac ggccgccgtt tactggggct
      901 tcaattcgta ccttcgcttg cgctaagcac tcctcttaac cttccagcac cgggcaggcg
      961 tcagccccta tacttcatct tacgattttg cagagacctg tgtttttgat aaacagtcgc
     1021 ttgggcctat tcactgcggc tgatcgtatg atcagcaccc cttctcccga agttacgggg
     1081 tcattttgcc gagttcctta acgagagttc tctcgctcac cttaggattc tctcctcgac
     1141 tacctgtgtc ggtttgcggt acgggccgct gttttctcac tagaagcttt tctcggcagt
     1201 gtgacatcag gaacttcggt actattattt ccctccccat cacagcttgt ccttaagaaa
     1261 agaagcattt gactcctctt cagacttact gcttggacag acatttccga tcgtctgcat
     1321 tccttagcct cctgcgtccc tccattgctc aaacaaaaac aacgggtaca ggaatatcaa
     1381 cctgttatcc atcgcctacg cctgtcggcc tcggcttagg tcccgactaa ccctgggcgg
     1441 acgagccttc cccaggaaac cttagtcatt cggtggacag gattctcacc tgtctttcgc
     1501 tactcatacc ggcattctca cttctaagcg ctccag
//
LOCUS       DAPBAF010000129         1435 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.141, whole genome shotgun sequence.
ACCESSION   DAPBAF010000129 DAPBAF010000000
VERSION     DAPBAF010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1435)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1435)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1435
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.141"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            105..1406
                     /locus_tag="RD451_002905"
     CDS             105..1406
                     /locus_tag="RD451_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HDT7568074.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKI
                     ENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
BASE COUNT          473 a          287 c          264 g          411 t
ORIGIN      
        1 gatagaaaat cattctatcg gtcccttttg agcatgaaaa aacaaaacat acagaagctc
       61 cgttagaatt gaatcaccac aacacaatca aaggagcgtt ctgtatgcct gatcttcatc
      121 atatcaaact actacttgga atcaaagata aaaacatttt catcacaaat gtggaatcga
      181 agagcattaa gaatatcaag agtcttgttg tttctgcgac gttaagtaaa gaaattcgtc
      241 gctgtccttt gtgtaaacag atgaatcatg aaggcatgat cgttaagaac ggaaagaaaa
      301 aatcgctcat tcaacttaat aaatgtgcga accaactgac ttatcttgct ttagcgaaac
      361 aacgctacca ctgtcgtggc tgccacacct attttacggc gaatacctac attgtcgata
      421 gaaactgctt tatcgctaaa caagtgcgct ataaaatttt agaagagcta actgaaaaac
      481 aagcaatgac gacaattgct aagcattgcg gcgtttcttg gtcgaccgtt tctcggacac
      541 tcgcttctct gatccccatg acaaaagtaa aaagaaattg gttaccgcgt tgtttattaa
      601 tggatgaatt tcgttcactg aaaaatcaag tcggtcccta ctccttttct tgtatggatg
      661 gcgatactgg aaaattactg gatattcttc cttcacggaa gaaaaaggct ctcgtttctt
      721 attttatgca atttgaacga cgcgcacgat tgaaggtaaa ggtcatcgtg acggacatga
      781 atgtttctta tgcctctctg ataaaggaat gttttccaaa ggcaaaactc gttgtggatc
      841 gttttcacat tgtcaaacat ctcattcgta aatttgagga tattcgcgta cgaatcatga
      901 aaagctttga tcgaaacgat ccaacacaag ccaaatatta tcgacaatta aaggcgttgt
      961 ctcggcttct gatcaaacga caggacaagc ttgtttatga caaatggacc aaatggcgca
     1021 attttggttg ggcgtatctc accgaaagtg aagtggtgga tcgtctgctt tcgatctctg
     1081 acgaattacg aatcgcctat ttttactatc aagaaattct tcaagcgttt cacgacaaag
     1141 aggcggacac tttctttaaa cttgtaagaa cgatgcccaa ttccgttcca aaagaactgc
     1201 attctataaa aaaagctttt ataaactatg aatccggcat tcgtttagcc ctcgaattgc
     1261 cttattcaaa tgccaaaata gaaaatctgc atacccacat caaagcattg aaacgagtcg
     1321 cttatggctt tcgaagcttt cggaaaatga agaccagaat tttcttacta aataatctga
     1381 ttacctatga atcaaaaaac atctaaagta gaaaaggaat tctaccttag atgtt
//
LOCUS       DAPBAF010000130         1427 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.142, whole genome shotgun sequence.
ACCESSION   DAPBAF010000130 DAPBAF010000000
VERSION     DAPBAF010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1427)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1427)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1427
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.142"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            102..1397
                     /locus_tag="RD451_002906"
     CDS             102..1397
                     /locus_tag="RD451_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HDT7568075.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFSLATREA
                     VQLIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHS
                     QRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAACPNLRQGYQ
                     LYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQNALHYSYSNGP
                     LECLNNHIKVLKRNAYGFRNFYNFKLRIMIRHGKTFLTK"
BASE COUNT          452 a          281 c          269 g          425 t
ORIGIN      
        1 ggtgaacttc accaacatct tttttgtata aaaaaatata gaaaagacac cctgaaatcc
       61 tttagaatta atttggctac caattcatag gaggattcaa gatgtctcat actcagctta
      121 tcaaagatac cctaaatatt ctagacctaa atatctattt cgaggaaaat tgtttaacta
      181 aagaaaaata caaagggcaa atttgcttga tttacaaagg aactcttctg tacaagccag
      241 aagagtgttc ccattgtctt tgtgtcgtcc cctctaggat cattcgttgg gggacgacaa
      301 ccgttcggtt gttactgaat gatgtgtctg agtatcgcac ttatctggag ctgaagaaac
      361 aacgatttaa atgtaagtct tgccaaagaa cattcgtagc ggatacctct gttgctgaaa
      421 aacactgttt cattagtcaa aaagttcgtt ggtctgtcat tgctcgctta aaagagaata
      481 cttccatgac ggaaatcgct cgtcagaaaa atatttccac ttcttcggtc tatcgtgtca
      541 tgaagcgatt ctaccgccca ttgaatcctt tcaaacagac tttgccaaag gtcttatgct
      601 ttgatgaatt caaatcggtt cgaagtgttg ccagtgcaat gagttttatc atgatggacg
      661 gacaaagcca tgcattattg gatattgtcg aaaatcgacg cttgccttat ttagaacgct
      721 atttttctcg gttttcatta gcgactcgtg aagccgttca attgattgtt attgatatgt
      781 atgcgcctta tgtttcgttg gtgaaaaagc ttttcccgaa tgctcagttg atcatcgatc
      841 gtttccacat cgtccaacat attggcagaa ctttcttgaa tcatcgagtg aaagaaacca
      901 cggtacgact taaaggaaat tcccactctc aacgagggtt agggaaaaaa ttgaagcgct
      961 attggaaact cctacaaaaa gaagaagcaa agttaaacta tgaaaaacgg gtttggcgtg
     1021 ccagttttaa agattatttg actgaaagtg agattgccga tcgactgtta gctgcttgtc
     1081 ccaacttacg ccaaggctat cagttatacc aagacattct ttatgcggta aagaaaagag
     1141 atcagtcact atttgaggat tgtttaacta gagacattag cggtctgcca gaaacctata
     1201 caaccacttt acgaacgttt aaaaagtttc tgccacagat ccaaaatgcg cttcactaca
     1261 gctattcaaa cggaccattg gaatgcttaa acaaccacat caaagtatta aaacgcaatg
     1321 cgtacggctt tcgcaacttt tacaatttca aactacgaat tatgattcgt catggcaaaa
     1381 catttttaac caaataaaca gaacagaaag aggttttctt ctttctg
//
LOCUS       DAPBAF010000131         1424 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.143, whole genome shotgun sequence.
ACCESSION   DAPBAF010000131 DAPBAF010000000
VERSION     DAPBAF010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.143"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(150..1337)
                     /locus_tag="RD451_002907"
     CDS             complement(150..1337)
                     /locus_tag="RD451_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HDT7568076.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
BASE COUNT          414 a          309 c          249 g          452 t
ORIGIN      
        1 taaaagttca acctcatcaa aagcacaatg ttttgcgttg tgaacctaac tgccatgcct
       61 ttctttctga ggagagaggt caggagcagt agcgcagcga ctcttgatgt ctctcctcag
      121 aaagaagaga ctcgcacagg ttcatggtgc taaatgttat tcgaattaaa ttctaaatat
      181 tttcgtggag aagccagcca ctcagtgtct ttttccatca aaagtgttcc aattatccga
      241 gtgatggaat tgatatttgg aaaaatccga atcactcgtt ctctccggcg aatctcttcg
      301 ttcaaccgtt ccaacacatt ggttgtacga atccttcggc ggatattttc aggaaaagac
      361 aaaatttgaa tagcatcttc aaagccgttt tctaaaatgt cgcaagcagc acttaatttt
      421 gaatcacaac catatttttc caagaagtgc tcttttcttt cacgtgtcaa ttcaagttca
      481 gaggctttaa agatactctt caactcgtct tttacatcag aagaaacttt ctttggcagc
      541 ttatcaaaaa tatttctcaa aaagtgggct tggcatcttt gccagctcgc acctaaaaag
      601 ttcttgcgaa cagccttaac taaccctttg tgtgcatcag aaatgaccag ttttacaccg
      661 aacaaacctc gttgaacgaa cgattgaaaa acggtatccc aattatcttc cgattcgccg
      721 tcttgaacat caaaaccaag aatcgtacgt cgtccatcag aatcaatgcc gataccaata
      781 tatacacctt ttgagacaat acgatgattt tcccttactt tcatatacag ggcatcacac
      841 atgaaaaatg gatattccga gccttctagg ctccggtttc tccactcaaa aacaaatgga
      901 tccaactgtt tcatcagatt tgaaacgaat gatttagaaa cagtcgcacc atccgttagc
      961 agttcaactg ttttagttac tttgcgagtg gagacaccag aaatgaccat ttcaatcatg
     1021 gcagcgatca aagctttttc gcttcgctga tatctttcaa agatagtagg actaaactta
     1081 ccgtctctgg ttcgtggaac atgaagttct aacgtaccaa ttcgagttgt aaacgaacga
     1141 tcgtagtaac catttctttg tgattgccgt tcttctgaac gttcataggc atttgcctga
     1201 atatattgat ttcgttgttc ttccatcagc tgattaaaca tgatagtcat aagtgttttt
     1261 gcggtatcat tcgcaccgct ttcgtttata attgcttgaa tttcttcgct ttcaaaagta
     1321 aaatgtactt gagtcattga tatcagtcct attcgagtat gttttctgca aaaaacattg
     1381 tactcctaac tgagatcaat ggcttttttg atgcttcact ttta
//
LOCUS       DAPBAF010000132         1352 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.145, whole genome shotgun sequence.
ACCESSION   DAPBAF010000132 DAPBAF010000000
VERSION     DAPBAF010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1352)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1352)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1352
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.145"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            82..>1352
                     /locus_tag="RD451_002908"
     CDS             82..>1352
                     /locus_tag="RD451_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HDT7568077.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNG
                     KIEAKNTHIKTMKRVSYGFKSFENMRIRIFL"
BASE COUNT          459 a          260 c          257 g          376 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcaccac aaaataaaca
       61 actgagagga cgatacgcta tatgaatgat tctatcaaaa aaatgctgag aataacagag
      121 aaagatttga tgattacaga ggtctcttac gagacccttc agaagaaaaa gacgttggtc
      181 gtcgatgctg ttctctcgcc tactcctcgt gcttgtagaa gttgtggttc tactgtggta
      241 gatggaaacg ggaaagcaat tatagtgaaa aatggaaaaa aggaaacgat tgtccgtttt
      301 gaacaataca atcatatgcc tttggttatg cgcctaaaaa agcaacgcta tacctgtaaa
      361 aactgtcgca cccattggac ggctcaaagt tattttgtcc aacccagaca ttcaatcgca
      421 aatcatgtta gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaagct gtcaggtatc tttgaccacc gttattcgta cattgaaaga gtttaaaagc
      541 tatttaccaa agcaatctaa gaagatcctc cccagagtat tgatggttga cgaatttcgt
      601 tcgcatgctt ccatagaaga taagatgagc tttatttgcg cggatggcga aacaggaaaa
      661 ttaatagatg ttttgcctac gcgtaaatta cctcgattaa caagctattt cttaggttgt
      721 accaatccag aagaagtaga attcttggtg acagacatga acgccgccta cttccagctc
      781 accaaacgtg ttctgccaaa tgcgaaagtc gtgattgatc ggtttcatat tgtcaaacac
      841 atgaatcaag cgttcaatga gttgcgtatc cgtgaaatga atgaacttcg taaagccgga
      901 cagaaaagcc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaata caaaacatgg aaaagtttcc gagcaccaaa atacccattt
     1021 cttactgaag caatgatgat tgatcgattg cttgagtttt ctccgcccct aaaggaggcg
     1081 tatccctttt ttcatgaatt agttgaagcc tttcgagaca aagaccctga cttatttttc
     1141 tccttattgg cagaacttcc cgaaacgtta gatgacagct ttcgggaaaa gcttcaaaac
     1201 cttctgacct atgaagaagg catcaccaac gcaatgatct atccttattc caatggaaaa
     1261 atagaagcga agaataccca cataaagaca atgaaacgag tatcctacgg atttaaatca
     1321 tttgagaaca tgagaattag aatctttttg at
//
LOCUS       DAPBAF010000133         1318 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.147, whole genome shotgun sequence.
ACCESSION   DAPBAF010000133 DAPBAF010000000
VERSION     DAPBAF010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1318)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1318)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1318
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.147"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(<1..374)
                     /locus_tag="RD451_002909"
     CDS             complement(<1..374)
                     /locus_tag="RD451_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDT7568078.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGANEGSSQVA
                     NNQYILLHETANETATGRNEAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGS
                     YANANSPVQIELQHTHDKATFE"
     gene            complement(371..595)
                     /locus_tag="RD451_002910"
     CDS             complement(371..595)
                     /locus_tag="RD451_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HDT7568079.1"
                     /translation="MNNKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIIT
                     GFGAFLGSVLGVSNRTYKMFSAESEEGGNK"
     gene            complement(592..885)
                     /locus_tag="RD451_002911"
     CDS             complement(592..885)
                     /locus_tag="RD451_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7568080.1"
                     /translation="MINLGEWGMIAGSITAIVSLILLVIRPIAASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHTEKLVEHTQQIKTLFRERRK"
     gene            complement(922..1059)
                     /locus_tag="RD451_002912"
     CDS             complement(922..1059)
                     /locus_tag="RD451_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HDT7568081.1"
                     /translation="MYSYEDIKLMYDWGCFTNEQVMVFVPLCITDEEADKIINKDKSA
                     S"
     gene            complement(1061..>1318)
                     /locus_tag="RD451_002913"
     CDS             complement(1061..>1318)
                     /locus_tag="RD451_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7568082.1"
                     /translation="KGNAVDSVDELANIKALYETLKAENDELKQLNSKAMLNNVAIKQ
                     ENVLLKEKSESLAQLNSKTMLASVQNTKEIEEIKKQLQGGK"
BASE COUNT          363 a          282 c          201 g          472 t
ORIGIN      
        1 ttctcaaacg ttgctttatc atgtgtgtgt tgtaactcaa tctgcacagg actgttggca
       61 ttagcatacg aaccagcacc gtactgtaca taaccaggtt gaccgacttg ataaacaatt
      121 ccgccgtctc ccacaatata agcagtataa gcgctagtcc atgaacgttg catatactgc
      181 gcttcattgc gtcctgttgc tgtttcatta gccgtttcat gcagtaaaat atactgatta
      241 tttgctactt gtgagctacc ttcatttgcg cccaaattaa attcattgtt gatagtatag
      301 gcaaatccgt taattggcaa taaaaaaaga gccgttaaca ggctcatcgc agtaatagta
      361 attttctttt tcatttgttt cctccttctt cgctttcagc cgagaacatt ttgtaggttc
      421 gatttgatac acccaacaca ctccctaaaa acgcgccaaa accagtaatg atgacaacac
      481 agatatctgt gtactgccaa ttgagcgctt taccaactaa ccccacgaaa gtagctagtg
      541 cgggaataat taccagtgcg aaccatttta gtacttcgaa cgttttatta ttcattttct
      601 tctctcccta aacaaagttt tgatttgttg cgtgtgttcc accaattttt ctgtatgtgt
      661 atctaatctt tcatcgtgtt tctttagttc ttcatgaatc atcaatcgat ctgatttgct
      721 cgattctaaa tctttagtca gcaaatctaa attgtggctt acttttgaaa gagtctcagt
      781 aattttcgag aaagatgcag caatcggtct aattactaat aaaatcaaag aaacgatagc
      841 ggttattgat cctgctatca ttccccattc ccctaaatta atcatgtgac aactccttta
      901 ccttaaataa aaacgcatca attaagatgc gctcttatct ttattaatga ttttatctgc
      961 ttcttcgtct gtaatgcata atggaacgaa aaccattact tgttcgttag tgaaacagcc
     1021 ccagtcatac attagtttga tatcttcata tgaatacatg ttacttccca ccttgtaatt
     1081 gttttttgat ttcttcgatt tccttggtat tttgtacaga agcaagcatc gtttttgaat
     1141 tcaactgcgc taaactttct gacttttctt tcaataagac attttcttgc ttgattgcta
     1201 cattgtttag cattgcttta gaatttagct gtttcaattc atcattttct gccttcagcg
     1261 tttcgtataa tgccttaata ttagccaatt catctacgct atcaacagca ttcccttt
//
LOCUS       DAPBAF010000134         1297 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.148, whole genome shotgun sequence.
ACCESSION   DAPBAF010000134 DAPBAF010000000
VERSION     DAPBAF010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1297)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1297)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1297
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.148"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            141..398
                     /locus_tag="RD451_002914"
     CDS             141..398
                     /locus_tag="RD451_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7568083.1"
                     /translation="MSKLENKEEKVVNKIVSVVNKLDKELDELDTLSENPEKKHNLKK
                     WLVERKAIHEIKKVLHEADKYEKYDEKELDKEFKEINDLLL"
     gene            complement(630..1061)
                     /locus_tag="RD451_002915"
     CDS             complement(630..1061)
                     /locus_tag="RD451_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HDT7568084.1"
                     /translation="MIGEKMMDQKAFIESIDSTIDRLKKEIRFYNRVIGIGNIIKIVL
                     SASIPILIDQASEHRSLLLIVSIASAIITIIQSGMSAFNYQDKVQTSTELLMKIEKEK
                     LLYITKTSPYNKTDEENFHLIVTTLQTELNDIISDFNQVNN"
BASE COUNT          492 a          169 c          161 g          475 t
ORIGIN      
        1 ttctgtccac gttcatatta ctccaaagtt ttcctcattc caaaagaaaa gcacagaata
       61 cacaaagaag cgtttttatt tgtataaact atatcaaagt tctatactta aattatcaaa
      121 taaaaaggac gtgaagataa atgtcaaaat tagaaaacaa agaagaaaaa gttgtaaaca
      181 aaattgtttc tgttgtcaat aaactggata aagagttaga cgaacttgat acgttatctg
      241 aaaatccaga aaaaaaacat aacctaaaaa aatggttagt tgaacgaaag gctattcatg
      301 aaattaaaaa agttcttcat gaagctgata aatatgaaaa atatgatgaa aaagaacttg
      361 acaaagaatt taaagaaatc aatgacttat tactataatt gatttatacg actcattttt
      421 gagtcgtcag actgcaaaca acactctaaa tttaggagtt tgtctacagt ctgaataaat
      481 tttaaattta ttgtccataa tgttattatg aatttatagc attaagaaaa gagataagac
      541 tttacatttt tttaggaatg taaagtctta tctcttttct taattgtaca attagtatta
      601 tctgcactac tttctaatta aataaatttt tagttattaa cttgattaaa atcagagata
      661 atatcattta attcagtttg aagggttgta acgattaaat ggaaattttc ttcatctgtt
      721 ttattatatg gggatgtttt cgttatatat aacaactttt ctttttcaat tttcattaat
      781 aactctgtcg aagtctgtac tttatcttga taattaaatg cagacatccc actttgtata
      841 attgtaatta ttgctgaagc aattgaaaca atcaatagta aagacctgtg ttcggaagcc
      901 tgatcaatta atattgggat actagctgat aagactattt ttataatatt tccgatacca
      961 attactctat tataaaatcg aatttctttt tttaatctat cgattgtaga atcaatagat
     1021 tcgataaacg ctttttgatc catcattttc tctccaatca ttttattaaa atcattaaca
     1081 aaaatattat aataggattt aagtaagttc taactaatca cacataaaaa taaaaaacat
     1141 ttgtatttta tcaaagtttt attatacttg tcaatttgtg tacatcctaa aatataagct
     1201 atttgtttac ttctgtagaa tatatacttt gttgttagat aagttgcaca tgtttataga
     1261 atctaaataa taaattttta tgtaccgccc ctccaaa
//
LOCUS       DAPBAF010000135         1246 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.149, whole genome shotgun sequence.
ACCESSION   DAPBAF010000135 DAPBAF010000000
VERSION     DAPBAF010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1246
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.149"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            200..742
                     /locus_tag="RD451_002916"
     CDS             200..742
                     /locus_tag="RD451_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7568085.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            898..>1246
                     /locus_tag="RD451_002917"
     CDS             898..>1246
                     /locus_tag="RD451_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HDT7568086.1"
                     /translation="MLSEKTDLENTEAFNKESVKDLRKLPTKDINGKDFTSKDFEKYD
                     LTMVNVFATWCTACVKEIPDLVEVQNEMKSKGVNIVGVVTDPVDDNGENKEAIEKSKL
                     IHEKTKASYPFLMP"
BASE COUNT          514 a          141 c          238 g          353 t
ORIGIN      
        1 attgatgaag cagatcccaa agggctgctt catcaatttt ttcgtaagtg tccgtacact
       61 tactgtgctt gctcatatat taatcgatca tatactaatc gtgtaagaac aactttaagc
      121 ataatactta tattgttata ccatagtttg gaaaaataaa aaattatatt tcatcaacgt
      181 ttcataaaag gtgtgtagaa tgttattgaa agtagctata aaatgctatt gtgtaaaaaa
      241 taaaggagga ataatttatg aaaaaatagt accaagagga gcatgcctat tacttgcatt
      301 atgtttgagc ttaagcgcag ttgggtgtca aaaaagtaat gaaaacaata aaataaaaga
      361 aggacaatcc ataagttctg aagaggaagg catgtcaatt aatgcaaatg gcaaaaatga
      421 aacttttaag ccatcagatt atacattgga ggcaaagaaa gaatatgttt atgaatattt
      481 agggcttaaa tttaaactct cagacaaatt tagaaattat atagctgata aaaagatagc
      541 gatgttagat gatcaaagtc ctatagataa agaactaaag tatgctattt tgacatttga
      601 gaaaatgaca gaagaacaaa agaatgcagt tatagaaaag atgggcgatg gatataaaaa
      661 ttggcaaaat gagcttgaaa gaattgggac tattggtata tttgaaaaaa atacatcaga
      721 agaaaaaaat ctaaaattat aaaatgtgat actcatacta aaataggagt ttcaagtgat
      781 ggaaaatacg attgctattt aagcacaaat agcggagctg aaagtaatct tctggatgaa
      841 ttaaaaagaa ctgagattca aattatagat aaaaaagaac gtcctaaaaa tggttttgtg
      901 ctatcagaaa aaactgattt agaaaataca gaagcattta acaaagaatc ggttaaagat
      961 ttacgtaaac taccaacaaa ggacataaat ggcaaggatt ttacaagtaa agattttgag
     1021 aagtatgatc ttactatggt aaatgtattt gcaacttggt gtacagcttg tgtaaaggaa
     1081 attcctgatt tggttgaggt tcagaatgaa atgaaaagca agggtgtaaa tatcgttgga
     1141 gttgttacag atcctgttga tgataacggt gaaaacaagg aagcaattga aaagtcaaag
     1201 ttaatacatg aaaagacaaa ggcttcatat cctttcttaa tgccag
//
LOCUS       DAPBAF010000136         1241 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.150, whole genome shotgun sequence.
ACCESSION   DAPBAF010000136 DAPBAF010000000
VERSION     DAPBAF010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1241)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1241)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1241
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.150"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            1..>1241
                     /locus_tag="RD451_002918"
     rRNA            1..>1241
                     /locus_tag="RD451_002918"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          375 a          245 c          363 g          258 t
ORIGIN      
        1 agtgaataag ggcgcacggt ggatgccttg gcactaggag ccgatgaagg acgggactaa
       61 caccgatatg ctttggggag ctgtacgtaa gctatgatcc agagatttcc gaatggggga
      121 acccaacatc tttaatagga tgttacgatt gtgtgaatac atagcacatt cgaggtagac
      181 gcagagaact gaaacatcta agtacctgca ggaagagaaa gaaaattcga ttccctgagt
      241 agcggcgagc gaaacgggaa aagcccaaac cagcaagctt gcttgttggg gttgtaggac
      301 tccaatatgg tagttctttc agatagtcga atgacttgga aaagtcagtc aaagagggta
      361 aaaaccccgt agacgaaatg tggaagacac ctaggaggat cctgagtacg gcggaacacg
      421 agaaattccg tcggaatccg ggaggaccat ctcccaaggc taaatactcc ctagtgaccg
      481 atagtgaacc agtaccgtga gggaaaggtg aaaagcaccc cggaagggga gtgaaataga
      541 acctgaaacc gtgtgcctac aacaagtcaa agcccgttaa tgggtgatgg cgtgcctttt
      601 gtagaatgaa ccggcgagtt acgattgcat gcgaggttaa gttgaagaga cggagccgca
      661 gcgaaagcga gtctgaatag ggcgtttgag tatgtagtcg tagacccgaa accatgtgat
      721 ctacccatgt ccaggttgaa ggtgcggtaa aacgcactgg aggaccgaac ccacgtacgt
      781 tgaaaagtgc ggggatgagg tgtgggtagc ggagaaattc caaacgaact tggagatagc
      841 tggttctctc cgaaatagct ttagggctag cctcggaatt gagaatgatg gaggtagagc
      901 actgtttgga ctaggggccc atctcgggtt accgaattca gataaactcc gaatgccatt
      961 cattcatatc cgggagtcag actgtgagtg ataagatcca tagtcgaaag ggaaacagcc
     1021 cagaccacca gctaaggtcc caaaatatat gttaagtgga aaaggatgtg gggttgcaca
     1081 gacaactagg atgttggctt agaagcagcc accatttaaa gagtgcgtaa tagctcacta
     1141 gtcgagtgac cctgcgccga aaatgtaccg gggctaaaca tattaccgaa gctgtggagt
     1201 acacctttag gtgtattggt aggagagcgt tctaagggcg t
//
LOCUS       DAPBAF010000137         1229 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.151, whole genome shotgun sequence.
ACCESSION   DAPBAF010000137 DAPBAF010000000
VERSION     DAPBAF010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1229)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1229)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1229
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.151"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            55..1217
                     /locus_tag="RD451_002919"
     CDS             join(55..331,331..1217)
                     /locus_tag="RD451_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HDT7568087.1"
                     /translation="MSKRTRRTFSQEFKQQIVNLYLAGKPRVEIIREYELTASAFDKW
                     VKQSKTSGSFKEKDNLTPEQKELLELRKRNQQLEMENDILKQAALIFGPKRQVIDANK
                     HLYPISAMCRILGLSRQSYYYQSKPKKDESELEEVVAEEFIRSRKAYGSRKIKKALSK
                     RGIQISRRKISRIMKNRGLKSSYTVAYFKVHHSTCNEAKTTNVLNRKFLRDNPLEAIV
                     TDLTYVRVGKKWNYVCFILDLFNREILGYSCGEHKDAVLVKKAFSRIKQPLTEVEIFH
                     TDRGKEFDNQAIDELLTTFDINRSLSHKGCPFDNAVAESTYKSLKVEFVYQYTFETLQ
                     QLDLELFDYVNWWNHLRLHGTLGYETPVGYRNQRLAQRILDNELGCANASEAV"
BASE COUNT          449 a          212 c          243 g          325 t
ORIGIN      
        1 gacagaaaaa ttaaggtgtg tagactagaa gaaaacatac caggaggaat ttttatgtct
       61 aagagaacac gaagaacttt ttcacaagaa ttcaagcaac aaatcgtcaa tctttactta
      121 gctggaaagc cacgtgtaga aatcattcga gaatatgaac taacggcttc agcatttgac
      181 aaatgggtaa agcaatctaa aacgagtggt tcattcaaag aaaaagataa tcttacgcct
      241 gaacaaaaag aattgttaga actacgtaaa agaaaccagc aattagaaat ggaaaatgat
      301 attttaaagc aagcagcgct gatattcgga cgaagagaca agtaatcgat gcgaataagc
      361 atctttaccc tatatcagcg atgtgcagaa tattaggtct atcacgtcag tcctattatt
      421 atcaatcaaa accaaagaaa gacgaatcag aacttgaaga agtagtcgct gaagaattta
      481 tccgcagccg aaaggcctac ggctcaagaa aaataaaaaa agccttatca aaacgaggca
      541 ttcagatcag ccgacgaaaa attagtagaa tcatgaaaaa tagaggatta aaatcgagct
      601 atactgttgc ttattttaaa gtacatcatt ctacttgcaa tgaagccaaa acgacaaacg
      661 tattgaatcg taaattctta agagacaacc cattagaagc gatcgtaaca gacttgactt
      721 atgtacgagt cgggaaaaaa tggaattatg tctgtttcat tttggatctg ttcaatcgag
      781 aaattctcgg ctattcttgt ggagaacata aagatgccgt tctagtaaaa aaagcattta
      841 gccgtatcaa acaacctctg acagaggttg agatttttca tactgatcgt ggaaaagagt
      901 ttgataacca agctattgat gaattattaa caacttttga catcaatcga tcattgagtc
      961 ataaaggctg tccttttgat aatgccgtag ctgaatcaac ttataagtcg ttgaaagtag
     1021 aatttgtcta tcaatacaca tttgaaacct tacaacaatt ggatttggag ttatttgact
     1081 atgtcaattg gtggaaccac cttcggttgc acggtacact tggctacgag acaccggttg
     1141 gttaccgtaa ccagagattg gcgcagcgaa tccttgataa tgagctcgga tgtgctaacg
     1201 ctagcgaggc agtctaactt taactgtta
//
LOCUS       DAPBAF010000138         1193 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.152, whole genome shotgun sequence.
ACCESSION   DAPBAF010000138 DAPBAF010000000
VERSION     DAPBAF010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1193)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1193)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1193
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.152"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            <1..1076
                     /locus_tag="RD451_002920"
     CDS             <1..1076
                     /locus_tag="RD451_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HDT7568088.1"
                     /translation="VIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFSR
                     MFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQHF
                     LENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGKG
                     RFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQV
                     IVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSWKVNQSGNYQS
                     QNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYKEVPKHQHKRALVLTARKF
                     TRLVDTLLRKHQLYTPPRSVIEK"
BASE COUNT          418 a          234 c          210 g          331 t
ORIGIN      
        1 ttgtgattgg catggagtca acgtccatgt acagcttcca tccttccatg ttttttcatg
       61 aagatgagaa actaaagaag ctcaacacac ttgtaacgat tgaaaatcct tttcgggtga
      121 aacaatttag tcgcatgttt gatgagaata aaactgatcg aaacgatgca ttaagaatcg
      181 ctgatttctt gcgtattcaa cgattcacaa cttcccctat caaagaagag aaatacatgg
      241 ccttacagcg tttaacacgt actcgctatc aacttattaa gcaattgatt cgtacaaagc
      301 aacattttct tgaaaatcta acgtacaaat gtaatacgct tgctcgagaa atgcgagacg
      361 aatcgacgag tctttttagt gcaaccctca tttcactcat gacggaagat ttcacattgg
      421 atgaacttgc tgagcttcct ttagaagctt tctgtgattt acttcaagaa aaaggaaaag
      481 gccgtttcaa gcaaccagaa aaaatcgcta aagcaattca acgtgcaatt accatgagtt
      541 accgcctagg tgctcttgca caagaatcaa ttaatgttgt tttaagtgtt ctcgtacgag
      601 aaatacgagc acttgaaaaa aatatcaaag aattagataa agccatcgaa caagtaattg
      661 ttgtcattcc agaatatcaa tgcttaacca gtattccagg cgttggtaaa gtctatgctg
      721 ccggtttaat cgctgaaatt ggtcaaatcg aaagatttga agatcagaca aaattggcaa
      781 aatacgctgg attaagttgg aaagtgaacc aatctggaaa ctatcagtcg caaaatacac
      841 ctctgacaaa acaaggaaat cgatatttta gatactactt agttgaagct gccaactctg
      901 taaaaaatta tcttcctgaa tacaaagctt tttatcaaag taaatataag gaggttccaa
      961 agcatcaaca caaacgtgca ctcgtcctaa ccgcaagaaa atttacgcgt ctggtggata
     1021 cgctactacg taaacaccaa ctctatacgc caccaaggag tgtgatagag aaataacaat
     1081 ccgttattga cgcaaatcct tgaatcaacc cgaaaaaaat ttgattttga tcgggtctag
     1141 tttcgtgcgc ttcaaaacat attactcaat aaagaaaatc ttaaatttca tct
//
LOCUS       DAPBAF010000139         1157 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.153, whole genome shotgun sequence.
ACCESSION   DAPBAF010000139 DAPBAF010000000
VERSION     DAPBAF010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1157
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.153"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(<1..365)
                     /locus_tag="RD451_002921"
     CDS             complement(<1..365)
                     /locus_tag="RD451_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDT7568089.1"
                     /translation="MKKKIFVGAIIALFLLPINAFAYTINNEFNLGANEGSSQVANNQ
                     YILLHETANETATGRNEAQYMKRSWYNAYTAYIVGDGGIVYQVGQPGYVQYGAGSYAN
                     ANSPVQIELQHTHDKVTFE"
     gene            complement(362..781)
                     /locus_tag="RD451_002922"
     CDS             complement(362..781)
                     /locus_tag="RD451_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HDT7568090.1"
                     /translation="MEKYLNTFSVMTGVIGGTIVGLLGGMDNILHVLIFLVGVDFLTG
                     LAKAWKLKEISSEIGFEGLLKKVLIFVVIAVAVEVQKIVGNSIPLREIVIMFYVANEG
                     ISFLENISVFLPLPDKLKEVFQQIRNDTENKDRGGTK"
     gene            complement(851..991)
                     /locus_tag="RD451_002923"
     CDS             complement(851..991)
                     /locus_tag="RD451_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HDT7568091.1"
                     /translation="MNSFPGFENIKQFYDWGCYTDQDLLDYVNMNCLTKDQYKQITGN
                     EI"
     gene            complement(984..>1157)
                     /locus_tag="RD451_002924"
     CDS             complement(984..>1157)
                     /locus_tag="RD451_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7568092.1"
                     /translation="SGTAVDDIEDVDQLKQLNALLTKQLAISVQEQEKMQQMLAQLTM
                     EVASIKNGGKSNE"
BASE COUNT          326 a          254 c          164 g          413 t
ORIGIN      
        1 ttttcaaacg ttactttatc gtgcgtatgt tgcagttcga tttgcacagg actatttgca
       61 ttagcatatg aaccagcgcc atattgtaca taaccaggtt gtccaacttg gtaaacgatc
      121 ccaccatcgc caacaatata cgctgtatag gcattgtacc aagaacgttt catgtactgc
      181 gcttcatttc gtcctgtcgc agtttcgttt gctgtttcat gcaataggat gtattggtta
      241 tttgctactt gagaactacc ttcgtttgcg cccaaattga attcattgtt gatcgtgtaa
      301 gcaaaggcgt ttattggcaa taaaaaaaga gctataatag ctcctacaaa gattttcttt
      361 ttcatttggt tcctcctcgg tctttatttt cagtatcatt tcgtatttgt tggaatacct
      421 cttttaactt atctggcaaa ggaaggaata ccgaaatgtt ttctaaaaaa ctaatccctt
      481 catttgcaac atagaacata ataactattt ctcttagagg tatagaattc ccaacgattt
      541 tctgtacttc aaccgcaacg gcaatcacaa cgaagattaa gactttcttc aacaatcctt
      601 cgaaacctat ctcactactt atttctttca atttccatgc cttagcaagt ccagttaaga
      661 agtccacacc cacaagaaaa attaaaacat gtagtatatt gtccatccct cccaataaac
      721 caacaattgt cccgcctatc acccctgtca ttactgagaa tgtatttaaa tatttttcca
      781 atatctattt ctcctttatg caaaaaagcg cactcgtttg agtacgcttt ttatttaact
      841 ttgtgcttaa ttaaatttca tttccagtaa tctgcttata ttggtctttt gttaaacagt
      901 tcatgtttac atagtcaagt aaatcttggt ccgtataaca tccccaatca taaaattgtt
      961 ttatattttc aaagcccgga aaactattca ttacttttcc ctccattctt aatacttgcg
     1021 acttccatcg tcaattgagc taacatttgt tgcatttttt cttgttcctg taccgatatc
     1081 gccaattgtt ttgtcagtag agcatttaat tgcttcaact gatcgacatc ttcaatatcg
     1141 tcaaccgctg tgccact
//
LOCUS       DAPBAF010000140         1143 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.154, whole genome shotgun sequence.
ACCESSION   DAPBAF010000140 DAPBAF010000000
VERSION     DAPBAF010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1143)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1143)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1143
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.154"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            <1..1125
                     /locus_tag="RD451_002925"
     CDS             <1..1125
                     /locus_tag="RD451_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEf1 family transposase"
                     /protein_id="HDT7568093.1"
                     /translation="NELFRSHLEKAINTLLRTELTAFLDYEKYDRTGFNSGNSRNGSY
                     FRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLETTIIHLFEKGVTMSEIADL
                     IEKMYGHHYTPQTMSNMTKVLTEEVNAFKSRALNDKYVAIFMDATYIPLKRQTVSKEA
                     IYIAIGIREDGTKEVLSYAIAPTESTYVWNELLQDINSRGVQEVLLFITDGLKGMKDT
                     IHQIYPKAKYQHCCIHVSRNIAHKVRVKDRKEICDDFKAVYQANSKEEANTFLSGMIE
                     KWKKNYPKVTQSLIENQDLLTFYDFPPSIRRTIYSTNLIESFNKQIKRYSRRKEQFQN
                     EESLERFLVSIFDTYNQKFLNRSHKGFQQVTDTLVSMFTE"
BASE COUNT          418 a          212 c          191 g          322 t
ORIGIN      
        1 aatgaattat tccgttcgca cttagaaaaa gcgataaaca cactcctacg gactgaatta
       61 acggcttttt tagattacga aaaatatgat cgcactggtt ttaattcagg taattcgaga
      121 aacggttctt actttcgatc aatcaaaacc gaatatggtg aattaacatt ggaaatacct
      181 agagatcgta atggtgagtt taaacaacaa actttaccag cctacaaaag aacaaacgat
      241 acattggaaa ccactattat ccatttattc gaaaaaggtg ttacgatgtc tgaaattgct
      301 gatttgatcg aaaaaatgta cggtcatcac tatactccac aaaccatgtc caacatgact
      361 aaagttctga ctgaagaagt aaatgccttt aaatccagag ccttaaatga taagtatgtc
      421 gctattttta tggacgctac ttacattcca ctaaaacgtc aaaccgtatc caaagaagcg
      481 atttatattg ccattggtat acgagaagac ggcactaaag aagtactgag ttatgcgatt
      541 gctccaactg aatcaacata cgtttggaat gagctgctac aggatattaa ctccagagga
      601 gttcaagaag tcttgctttt tattacggac ggcttaaaag gcatgaaaga tactatccat
      661 caaatttatc ctaaagcaaa atatcagcat tgttgtatcc atgtatctcg taacatcgct
      721 cataaagtac gtgtcaaaga ccgaaaagaa atctgtgatg actttaaggc tgtttatcaa
      781 gctaactcaa aagaagaagc gaataccttc ttatccggca tgattgagaa atggaagaaa
      841 aactatccta aagtgacgca gtcactcata gaaaaccaag acttattaac tttttatgat
      901 tttccaccta gcattcgtag aaccatttac tcaaccaatc taatcgagtc tttcaataag
      961 caaattaaaa gatacagccg tagaaaagag cagtttcaaa atgaagaatc actagaacgc
     1021 tttctagtca gcatttttga tacatacaat caaaaatttc taaacagaag ccataaaggt
     1081 tttcaacagg taaccgatac attagtttca atgtttactg agtaactaat tattttgcag
     1141 gag
//
LOCUS       DAPBAF010000141         1126 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.155, whole genome shotgun sequence.
ACCESSION   DAPBAF010000141 DAPBAF010000000
VERSION     DAPBAF010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1126)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1126)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1126
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.155"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            82..>1126
                     /locus_tag="RD451_002926"
     CDS             82..>1126
                     /locus_tag="RD451_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa5 family transposase"
                     /protein_id="HDT7568094.1"
                     /translation="MNDSIKKMLRLIEKDLMITEVSYETFQKKKTLIVDAVFSPAPHT
                     CRNCGSTVVDGNGKVIVVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKNCQVSLTTVIRTLKEFKSYLPKQSK
                     RILPRVLMVDEFRSHASIEDKMSFICADGETGQLIDVLPTRKLPRLTSYFLGCANPEE
                     VKFLVTDMNAAYFQLTKRILPNAKVVIDRFHIIKHMNQAFNELRIREMNELRKVGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLGFSTSLKEAY
                     PYFHELVEAFRDKD"
BASE COUNT          377 a          207 c          219 g          323 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcacgac aaaataaaca
       61 actgagagga cgatatgcta tatgaatgat tctatcaaaa aaatgctgcg attaatagag
      121 aaagatttga tgattacaga ggtctcttac gagacctttc agaagaaaaa gacgttgatc
      181 gtcgatgctg ttttctcacc tgctccccat acctgtagaa attgtggttc tactgtggta
      241 gatggaaacg ggaaagtaat tgtagtgaaa aatgggaaga aggaaacgat tgtccgcttt
      301 gaacaataca atcacatgcc tttggttatg cgcttaaaaa agcagcgcta tacctgtaaa
      361 aactgtcgaa cccattggac ggctcaaagt tattttgttc aacccagaca ttcaatcgcg
      421 aatcatgtca gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaaatt gtcaggtatc tttgaccacc gttattcgta cgttgaaaga gtttaaaagc
      541 tacttaccaa agcaatctaa gaggattctc cccagagtat tgatggttga tgaatttcgt
      601 tcgcacgctt ccatagaaga taaaatgagc tttatttgcg cagatggcga aacaggacaa
      661 ttaattgatg tcttgcctac gcgtaaattg cctcgattaa caagctattt cttaggctgc
      721 gctaatcctg aagaagtaaa atttttagtc acagacatga acgccgccta cttccagctt
      781 accaaacgta ttctgccaaa tgcgaaagta gtgattgatc ggtttcatat tatcaaacac
      841 atgaatcaag cctttaatga gttgcgtatc cgtgaaatga atgaacttcg taaagtagga
      901 cagaaaagtc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaata caaaacatgg aaaagttttc gagcaccaaa atacccattt
     1021 cttacggaag cgatgatgat tgatcgattg cttggctttt ctacgtccct gaaggaggcg
     1081 tatccctatt ttcatgaatt agttgaagcc tttcgagaca aagacc
//
LOCUS       DAPBAF010000142         1061 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.156, whole genome shotgun sequence.
ACCESSION   DAPBAF010000142 DAPBAF010000000
VERSION     DAPBAF010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1061)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1061)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1061
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.156"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(36..992)
                     /locus_tag="RD451_002927"
     CDS             complement(36..992)
                     /locus_tag="RD451_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7568095.1"
                     /translation="MELYTLPIIIKTEKMLKDLKQYYPLSAYEKKKLFHFLAINLLAE
                     QADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFINKTLSWLYLHDKLDQKYLRKNED
                     ETIEWLNERFIESFENQFNLLREETSQLIRRELTKIHFKLLHYTINKADEFPLDVSFF
                     RENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFSYLLLLINHIPIQLISEPVKIIID
                     FSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPDVIITNRNNLYEESASQVVVWLDP
                     PRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPEEIIDRIE"
BASE COUNT          346 a          177 c          160 g          378 t
ORIGIN      
        1 tagaaaaagc agtcggactt tctaaaagaa gttcactatt cgatcctgtc gatgatttct
       61 tcaggaaaat cgtctatttg cttgtcaatt ttgctgtctt tgtatttctc ttcttggata
      121 gtcaacaaaa tctttgtaag attcccccag tctactgctc ttggcggatc gagccaaacc
      181 actacttgag atgcactttc ttcatataga ttattcctat tcgtgattat aacatccggg
      241 aactcaggct ttcctgcctc tatcacttcc gtgttcagat taatgtacaa gcttaaattt
      301 ttcttgataa attgattata ggcagcacca taagaaaaat cgatgatgat ctttactggt
      361 tcagaaatca gttgaatggg tatgtgattg atcaataata ataaataact gaaaaaaaga
      421 aaaaatttat cttgaagcaa ctctttgcgt tttgacgtta gatcatttat atactctatc
      481 aaatagcaat aaaatgctgg atagttttct ctaaaaaaag aaacatcaag tggaaattca
      541 tcagctttat taatagtgta atgcaaaagt ttaaaatgta ttttggttaa ctctcttcgg
      601 atcaattggc tcgtctcttc tcgcaacaga ttaaactgat tttcaaaact ttcaatgaat
      661 cgttcattca accattcgat tgtttcatct tcattttttc tcaagtattt ttgatccaat
      721 ttatcatgaa gataaagcca agagagtgtc ttattgataa aaataacgga tttttctcct
      781 aatactcctt ttaagtggta aaatcctata tccgaaaaaa atagcgactg attgctagca
      841 atatctaaag aatcagcttg ttcagccaac aggttgattg ctaaaaagtg gaataatttc
      901 tttttttcat aagcagacag aggataatac tgttttaaat cttttaacat tttttctgtt
      961 tttataatta taggtagcgt atacaattcc acaaaactta tctctgttga gttaaaaaga
     1021 ttatataaaa aaagccgaat gtttttagga ttccctgtca a
//
LOCUS       DAPBAF010000143         1039 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.157, whole genome shotgun sequence.
ACCESSION   DAPBAF010000143 DAPBAF010000000
VERSION     DAPBAF010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1039)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1039)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1039
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.157"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            42..>1039
                     /locus_tag="RD451_002928"
     CDS             42..>1039
                     /locus_tag="RD451_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001878362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetM/TetW/TetO/TetS family tetracycline
                     resistance ribosomal protection protein"
                     /protein_id="HDT7568096.1"
                     /translation="MCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIR
                     FQNCSLFPLYHGSAKSNIGIDNLIEVITNKFYSSTHRGPSELCGNVFKIEYTKKRQRL
                     AYIRLYSGVLHLRDSVRVSEKEKIKVTEMYTSINGELCKIDRAYSGEIVILQNEFLKL
                     NSVLGDTKLLPQRKKIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDS
                     TTHEIILSFLGKVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPN
                     PFWASIGLSVSPLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVT"
BASE COUNT          363 a          158 c          216 g          302 t
ORIGIN      
        1 ccgaaattgt aatcaaacag aaggtagaac tgtatcctaa tatgtgtgtg acgaacttta
       61 ccgaatctga acaatgggat acggtaatag agggaaacga tgacctttta gagaaatata
      121 tgtccggtaa atcattagaa gcattggaac tcgaacaaga ggaaagcata agatttcaga
      181 attgttctct gttccctctt tatcatggaa gtgcaaaaag taatataggg attgataacc
      241 ttatagaagt tattactaat aaattttatt catcaacaca tcgaggtccg tctgaacttt
      301 gcggaaatgt tttcaaaatt gaatatacaa aaaaaagaca acgtcttgca tatatacgcc
      361 tttatagtgg agtactacat ttacgagatt cggttagagt atcagaaaaa gaaaaaataa
      421 aagttacaga aatgtatact tcaataaatg gtgaattatg taagattgat agagcttatt
      481 ctggagaaat tgttattttg caaaatgagt ttttgaagtt aaatagtgtt cttggagata
      541 caaaactatt gccacagaga aaaaagattg aaaatccgca ccctctacta caaacaactg
      601 ttgaaccgag taaacctgaa cagagagaaa tgttgcttga tgcccttttg gaaatctcag
      661 atagtgatcc gcttctacga tattacgtgg attctacgac acatgaaatt atactttctt
      721 tcttagggaa agtacaaatg gaagtgatta gtgcactgtt gcaagaaaag tatcatgtgg
      781 agatagaact aaaagagcct acagtcattt atatggagag accgttaaaa aatgcagaat
      841 ataccattca catcgaagtg ccgccaaatc ctttctgggc ttccattggt ttatctgtat
      901 caccgcttcc gttgggaagt ggaatgcagt atgagagctc ggtttctctt ggatacttaa
      961 atcaatcgtt tcaaaatgca gttatggagg ggatacgcta tggctgtgaa caaggattgt
     1021 atggttggaa tgtgacgga
//
LOCUS       DAPBAF010000144         1039 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.158, whole genome shotgun sequence.
ACCESSION   DAPBAF010000144 DAPBAF010000000
VERSION     DAPBAF010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1039)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1039)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1039
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.158"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            42..>1039
                     /locus_tag="RD451_002929"
     CDS             42..>1039
                     /locus_tag="RD451_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001878362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetM/TetW/TetO/TetS family tetracycline
                     resistance ribosomal protection protein"
                     /protein_id="HDT7568097.1"
                     /translation="MCVMSCTEPEQWDVVIEGNDDLLEKYMSGKSLEALELEQEEIRR
                     FQNCSLYPVYHGSAKSNIGIEQLIEVITNKFYSSTYRKKSELCGNVFKIEYSEERQRL
                     AYVRLYGGILHLRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKL
                     NSVLGDTKLLPQRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLQYYVDS
                     TTHEIILSFLGKVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPN
                     PFWASIGLSVSPLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVT"
BASE COUNT          360 a          163 c          228 g          288 t
ORIGIN      
        1 tggaaattat aatcaaacag aaagtagagc tgcaccctaa tatgtgtgtg atgagctgta
       61 cggaacctga gcaatgggat gtggtaatag aaggaaatga tgacctttta gagaaatata
      121 tgtccggtaa atcattagaa gcattagaac tcgaacaaga ggaaatcaga agatttcaga
      181 attgctcctt gtaccctgtt tatcatggaa gcgcaaaaag caacataggg attgagcagc
      241 ttatagaagt gataacgaat aaattttatt catcaacata cagaaagaag tctgaacttt
      301 gcggaaatgt cttcaaaatt gaatattcgg aagaaagaca acgtcttgca tatgtacgcc
      361 tttatggcgg aatcctgcat ttgcgggatt cggttagaat atcggaaaag gaaaaaataa
      421 aaattacaga aatgtatact tcaataaatg gtgaattatg taaaattgat aaggcttatt
      481 ccggggaaat tgttattttg caaaatgagt ttttgaagct aaatagtgtt cttggagata
      541 caaagctatt gccacagaga gagagaattg aaaatccgct ccctctgctg caaacaactg
      601 ttgaaccgag caaacctcaa caaagggaaa tgttacttga tgcactttta gaaatctccg
      661 acagtgaccc gcttctacaa tattatgtgg attctacgac acatgaaatt atactttctt
      721 tcttagggaa agtacaaatg gaagtgatta gtgcactgtt gcaagaaaag tatcatgtgg
      781 agatagaact aaaagagcct acagtcattt atatggagag accgttaaaa aatgcagaat
      841 ataccattca catcgaagtg ccgccaaatc ctttctgggc ttccattggt ttatctgtat
      901 caccgcttcc gttgggaagt ggaatgcagt atgagagctc ggtttctctt ggatacttaa
      961 atcaatcatt tcaaaatgca gttatggaag ggatacgcta tggttgcgaa caaggattat
     1021 atggttggaa tgtgacgga
//
LOCUS       DAPBAF010000145         1000 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.159, whole genome shotgun sequence.
ACCESSION   DAPBAF010000145 DAPBAF010000000
VERSION     DAPBAF010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1000)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1000)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1000
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.159"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            369..1000
                     /locus_tag="RD451_002930"
                     /pseudo
     CDS             369..1000
                     /locus_tag="RD451_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          342 a          181 c          183 g          294 t
ORIGIN      
        1 tttcaaagtt agtagagaaa atgtagttat atatttaaat ttttaccaga aagaaatgaa
       61 caccttcaat tatctaaatc tcgaaaatgg ttagatgtaa tcatcaggaa aaacaatctt
      121 aaacgaatta ctattcatgg tcttagacac acacatgcta gcttgctttt agcaagctag
      181 tgcaaatatt aaagatgtgc aagagcgttt aggccactct tctattcaaa tcattatgga
      241 tctatatatt catattacag acaaaagaaa agaagaaacc gtagcgcaat tcgcaaaata
      301 taggctctat aatttatggg actgatgaat caaaattgat tcttcagtcc cattgttatt
      361 ttaggtatat gattcgtaca ttgaaagagt tgaaaaacta tcttccgaag ccgtcaaaaa
      421 ggaccctgcc aaaagtattg atggtggatg aatttcgttc gcacgcttca attgtggata
      481 aaatgagctt tatttgtgcg gatggcgaga ctggaaaact cattgatatt ttgcctacac
      541 gaaaattgtc tcgattaaca cactatttta gtcgctgtgc aaatcctgaa gcggtggaat
      601 atttagtgac agatatgaac gccgcctact tccaactgac aaaacgtgtc ttaccaaatg
      661 cgaaagtcgt cattgattgt tttcatatca tcaaacattt gaatcaggcg ttcaatgatt
      721 ttcgtgtaca agaaatgaaa agattacacc agttagggca acgacgggaa gccgagaaag
      781 tgaaaaagaa ctggcgcttt cttctaaaaa accgtcaaaa aatcaatcac tatgattaca
      841 aaacatggcg cagttttcgt gcacctaaat acccgctact cactgaagca atgatgattg
      901 atcgattgct ggcattttca acgcctttaa aggacgccta tacttttttc catgagctga
      961 ccgaagcctt tagagacaag gaatcagact tattttttac
//
LOCUS       DAPBAF010000146          994 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.160, whole genome shotgun sequence.
ACCESSION   DAPBAF010000146 DAPBAF010000000
VERSION     DAPBAF010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 994)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 994)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..994
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.160"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(<1..>994)
                     /locus_tag="RD451_002931"
     rRNA            complement(<1..>994)
                     /locus_tag="RD451_002931"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          209 a          307 c          225 g          253 t
ORIGIN      
        1 agcacgtgtg tagcccaggt cataaggggc atgatgattt gacgtcatcc ccaccttcct
       61 ccggtttgtc accggcagtc ttgctagagt gcccaactga atgatggcaa ctaacaataa
      121 gggttgcgct cgttgcggga cttaacccaa catctcacga cacgagctga cgacaaccat
      181 gcaccacctg tcactttgcc cccgaagggg aagctctatc tctagagtgg tcaaaggatg
      241 tcaagacctg gtaaggttct tcgcgttgct tcgaattaaa ccacatgctc caccgcttgt
      301 gcgggccccc gtcaattcct ttgagtttca accttgcggt cgtactcccc aggcggagtg
      361 cttaatgcgt tagctgcagc actgaagggc ggaaaccctc caacacttag cactcatcgt
      421 ttacggcgtg gactaccagg gtatctaatc ctgtttgctc cccacgcttt cgagcctcag
      481 cgtcagttac agaccagaga gccgccttcg ccactggtgt tcctccatat atctacgcat
      541 ttcaccgcta cacatggaat tccactctcc tcttctgcac tcaagtctcc cagtttccaa
      601 tgaccctccc cggttgagcc gggggctttc acatcagact taagaaaccg cctgcgctcg
      661 ctttacgccc aataaatccg gacaacgctt gccacctacg tattaccgcg gctgctggca
      721 cgtagttagc cgtggctttc tggttagata ccgtcaaggg atgaacagtt actctcatcc
      781 ttgttcttct ctaacaacag agttttacga tccgaaaacc ttcttcactc acgcggcgtt
      841 gctcggtcag actttcgtcc attgccgaag attccctact gctgcctccc gtaggagttt
      901 gggccgtgtc tcagtcccaa tgtggccgat caccctctca ggtcggctat gcatcgtggc
      961 cttggtgagc cgttacctca ccaactagct aatg
//
LOCUS       DAPBAF010000147          756 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.161, whole genome shotgun sequence.
ACCESSION   DAPBAF010000147 DAPBAF010000000
VERSION     DAPBAF010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 756)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 756)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..756
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.161"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(91..>756)
                     /locus_tag="RD451_002932"
     CDS             complement(91..>756)
                     /locus_tag="RD451_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEfa8 family transposase"
                     /protein_id="HDT7568098.1"
                     /translation="RRRIGRIMKRRGLTSTYTIAHFKGQRTACNEAKTANVLDRTFTQ
                     EQPLEAIVTDLTYVRVGKKWHYICLILDLFNREIIGYSCGEKKDASLVKEAFGRIPYS
                     LTDVKLFHTDRGKEFDNQTIHEILNGFGITRSLSRKGCPYDNAVVESTYKSVKVEFVH
                     QYQFETLAQLRLELFDYVHWWNYLRLHGTLAYETPIQIRQQRLAKRILDNERGSDTSG
                     EAA"
BASE COUNT          204 a          178 c          146 g          228 t
ORIGIN      
        1 ttgtgaatgc tgcggtgtta tggctacgat tgcccttgac aatgagcatc ctcggatctg
       61 attttctccg gcagaagcac aatcattcaa ttacgctgcc tctccagagg tatcagatcc
      121 gcgctcatta tcaaggattc gcttcgccaa tctctgttgt cgaatttgga tcggtgtttc
      181 atacgccaac gtgccatgta agcgtagata gttccaccaa tgcacataat caaacaattc
      241 tagacgtagc tgtgccagtg tctcaaattg gtattgatgc acgaattcta ctttgacaga
      301 tttataggtt gattccacaa cggcattatc atacggacaa cccttcctac tcaatgaacg
      361 agtaattcca aaaccattca gaatctcatg aatggtttgg ttatcaaatt cctttccccg
      421 gtctgtatga aaaagcttga cgtctgttaa agaatacggt atccgtccaa aggcttcttt
      481 taccaatgag gcatctttct tctcaccaca ggaataacca ataatttctc gattaaacaa
      541 atcaagtatt aagcagatat aatgccactt tttccccacg cgaacataag taagatccgt
      601 aacgatggct tccaatggct gttcttgtgt aaaggtccga tctaatacat tcgctgtttt
      661 cgcttcatta caagctgttc gttgcccttt aaaatgagcg atcgtatagg tagatgtcaa
      721 tccgcggcgt ttcatgattc gaccgattcg gcgccg
//
LOCUS       DAPBAF010000148          755 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.162, whole genome shotgun sequence.
ACCESSION   DAPBAF010000148 DAPBAF010000000
VERSION     DAPBAF010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 755)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 755)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..755
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.162"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
BASE COUNT          261 a          123 c          111 g          260 t
ORIGIN      
        1 tgcgagcagc aactagaata atttaaacat tattaaactg tctatattgt tactaataat
       61 tcccttctta tagtgcattt tcttagaaaa aaacaatatt acgatatcat gatattaaga
      121 tatcgtaata ttatacaatt gtgattgata ttatatatgt ttttttattt ttttatcatg
      181 tttaatcttg aaggaatcat attctttttc taaagacagg agcttttcat aaacatcaga
      241 catgtttaaa ctagaggcca ggcttaaatc ataaacgaat gaagcaggta atgattttat
      301 tctacgttgt cgggttatcc agcttgcaac cgttccttgt gggtaggcat ataactcaca
      361 aaattgttct acagtgattc ctaaattctt gataatgtaa acattgatcg ggtgcgagta
      421 aacaaatgta ttgatagaca tggtgcgtaa gcctactttc ttttattatt gcgtttgcaa
      481 taatagttta acacacgcat tattctagta tctactccta tttgtaaaaa caaaaaagga
      541 ttcatagaga taactctata gaatccgtaa aataccttat atatataacg ggaaaatata
      601 aaacctaaaa ttatgataac ctgctgcagc ttctacatag aaagagaagc gctcaacacc
      661 aacctcattt atcaaacgtt ggccataacc ccaaatctct tctgatagct gatcaaaggt
      721 tatatacttt agctcatatt gctggataat gttca
//
LOCUS       DAPBAF010000149          736 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.163, whole genome shotgun sequence.
ACCESSION   DAPBAF010000149 DAPBAF010000000
VERSION     DAPBAF010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 736)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 736)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..736
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.163"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            <1..734
                     /locus_tag="RD451_002933"
     CDS             <1..734
                     /locus_tag="RD451_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HDT7568099.1"
                     /translation="DKYSKIKQEITAIVKESRNSYGYRRVTLALKMKGYTINHKTVRK
                     LMSQMGLTCQIRIKRYKSYKGTVGKIAKNVLKRNFSVDTPNKKWVTDVTEFKIKGRKI
                     YLSPILDLFNGEIISYSISTSPTYKLIEEMLQQAIKKKGTEGSLILHSDQGWQYQMPQ
                     YQKKLKENNIIQSMSRKGNCLDNSVIENFFGVLKSEFFYREKFRSIEIFQSKLNEYIR
                     WYNNKRIKLKLNGLSPVEYRKQSIK"
BASE COUNT          318 a           94 c          122 g          202 t
ORIGIN      
        1 cagataaata tagcaagata aagcaagaaa ttacagcgat tgtaaaagaa tcaagaaact
       61 cttatggtta tcgtagagtc actttagcgt taaagatgaa aggatataca atcaatcata
      121 aaacagttag aaaattaatg tcccaaatgg gacttacctg tcaaatccga ataaagcgat
      181 ataaatctta taaaggaaca gtaggaaaaa ttgccaagaa tgtgttaaaa cgaaattttt
      241 cagtagatac acccaataaa aaatgggtga cagacgtcac tgaattcaag ataaaaggaa
      301 gaaaaatcta tctatctcct atacttgatt tatttaacgg agaaataatt agttatagta
      361 tatcaactag tccaacatat aaactgattg aagaaatgct tcaacaagca attaaaaaaa
      421 agggaactga gggttcactg attctacatt cagatcaagg atggcagtat cagatgccac
      481 aatatcaaaa aaaattaaaa gagaataaca ttattcaaag catgtctaga aaaggaaatt
      541 gcttagataa ttctgtaata gaaaattttt ttggtgtgct taaatcagag tttttttatc
      601 gagaaaaatt ccgatcaatt gagatatttc aaagtaaatt aaatgagtat attaggtggt
      661 ataataacaa aaggataaaa ctaaagttaa atggactatc tccagtagaa tatcggaaac
      721 agtccattaa atagtt
//
LOCUS       DAPBAF010000150          732 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.164, whole genome shotgun sequence.
ACCESSION   DAPBAF010000150 DAPBAF010000000
VERSION     DAPBAF010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 732)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 732)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..732
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.164"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            21..>732
                     /locus_tag="RD451_002934"
     CDS             21..>732
                     /locus_tag="RD451_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HDT7568100.1"
                     /translation="MTYTHLTTDELVIIESYFKMNQSVAKTAHCLNRSRQTIHKVYLF
                     FKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIS
                     CSARTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFK
                     SITFDCGKEFSNWKQISNV"
BASE COUNT          257 a          127 c          138 g          210 t
ORIGIN      
        1 attataagga gtgagtacaa atgacctata cccatcttac aacggatgaa cttgtaataa
       61 tagagtctta tttcaaaatg aatcaatctg ttgctaaaac tgcccattgc ttgaatcgtt
      121 caagacaaac gatccataaa gtatatctgt tcttcaagca aggaaaatca gccttagaat
      181 attatcaaca gtataagaaa aacaaatcaa actgtggtag acgtccgctt gttttacccg
      241 aggaacaatc agaatatatt caaagaaagg ttgttcaagg atggacaccc gatgtgattg
      301 ttggtcgtgc agcgtttcct attagttgtt ctgctcgtac catttatcgt atgttcaaaa
      361 aggggctatt tgattcttct gacttaccga tgaaaggcaa gcgtaaaccg aatggacatc
      421 aagaaagacg tggaaaacaa actttccgcc gctctattca tgaacgtgaa aaggattata
      481 gccaattctc aaatgagttt ggtcaccttg aaggtgacac tatcgtaggt ctgaaacata
      541 aaagtgctgt aattacctta gttgaacgat tatcaaaagt tatcatcaca ttgaaaccgt
      601 gtggtagaca agcgattgat attgaaaaaa aattaaatca atggtttgaa tctgtaccga
      661 aaaacctatt caaatccatc acttttgatt gtggaaagga attttcaaat tggaaacaga
      721 tcagtaatgt ca
//
LOCUS       DAPBAF010000151          656 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.165, whole genome shotgun sequence.
ACCESSION   DAPBAF010000151 DAPBAF010000000
VERSION     DAPBAF010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 656)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 656)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..656
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.165"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(138..491)
                     /gene="tnpB"
                     /locus_tag="RD451_002935"
     CDS             complement(138..491)
                     /gene="tnpB"
                     /locus_tag="RD451_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HDT7568101.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
     gene            complement(481..>656)
                     /locus_tag="RD451_002936"
     CDS             complement(481..>656)
                     /locus_tag="RD451_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7568102.1"
                     /translation="VPVQLGNEKSAPEKGKPAAAKLAMRIKRENGSEVLIYNGINNYI
                     LQAILKELLSNAL"
BASE COUNT          198 a          143 c          111 g          204 t
ORIGIN      
        1 ttgaagcaac tgaagcaacg tatctgtagt ttccaaaatt tttcaccacc ttgaatcgaa
       61 ctgattttgt tacagaatac cacaagaaac gcacaagaaa taggggttca acacattttt
      121 tgtgttaacc ccccagctta aaaaactcct ttttttcctg gcaaaatagc tcgaggttga
      181 tcgatactta atccttctaa caaccatcga acctgttggt tcgttaaggt tcgaacttcg
      241 tctttcgtcc gaggccattt taacttgccg ttttctatcc gcttataaca gagaagaaaa
      301 ccatcaccgt cccaatagag aagtttgaaa cggtcttgac ggttcccgca aaataaaaaa
      361 acggcatctt cgtaaagctc gagttgatac tcttgttgaa taagactggc aagaccatca
      421 attccttttc gcaaatctgt ttttccgcac acaatataaa tatgtttggt ttgaagtaaa
      481 tcataaagca ttggacaaca gttctttcaa aatagcttga agaatataat tgttaatacc
      541 gttatagatc aaaacttcag aaccattctc tcttttgatg cgcatcgcta acttggcagc
      601 cgcgggttta cctttttctg gtgcactctt ttcgtttcct aattggacag gaacaa
//
LOCUS       DAPBAF010000152          655 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.166, whole genome shotgun sequence.
ACCESSION   DAPBAF010000152 DAPBAF010000000
VERSION     DAPBAF010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 655)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 655)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..655
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.166"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(<1..>655)
                     /locus_tag="RD451_002937"
     CDS             complement(<1..>655)
                     /locus_tag="RD451_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS1182-like element ISEfa7 family transposase"
                     /protein_id="HDT7568103.1"
                     /translation="LVKQSKRLFPEINCVVADAGYKTPKFVHFLTHLNLRPCLPYSRP
                     KGKKGLLSKNEFLYDEYFDCYICPQDQMLAFSTVTREGYREYKSNPKECVNCPLLNQC
                     TISKNHQRVITRHVWGDLMDEVEHLRLTDLNKSIYKKRKQTIERIFADAKEKHGMRWT
                     KYRGLEKVATHTMLVFAAMNLKKLATWLWKGKEPLFFCSKIRNEVDKKLFQARVTSL"
BASE COUNT          181 a          141 c          116 g          217 t
ORIGIN      
        1 tccaaactcg taactcgagc ttggaacagc tttttatcta cttcgtttcg aatttttgaa
       61 caaaaaaata aaggctcctt gcctttccat agccaggtgg ctaatttctt taaattcatt
      121 gcagcaaaca ctagcatcgt atgcgtcgcg actttttcca agcctcgata cttggtccaa
      181 cgcatcccat gcttttcttt tgcatccgca aatattcgtt caatcgtttg tttccgtttt
      241 ttgtaaattg atttattcag atctgttagg cgaagatgtt ccacttcatc catcagatct
      301 ccccaaacat gtctcgtgat gactcgttga tgatttttac ttatggtaca ttggtttagc
      361 agaggacagt tcacacattc ttttggattg gatttgtatt ctcggtaccc ttctcgagta
      421 accgttgaaa aagcgagcat ttgatcttgc ggacaaatat aacaatcaaa atactcgtca
      481 tagagaaact cattttttga taatagcccc tttttccctt tgggccttga ataaggcaaa
      541 caaggtcgaa ggttcaaatg agtcaaaaag tgaacaaact taggtgtctt atacccagca
      601 tcagcgacaa cacaattgat ttcaggaaaa agtctcttcg attgtttgac gagct
//
LOCUS       DAPBAF010000153          605 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.167, whole genome shotgun sequence.
ACCESSION   DAPBAF010000153 DAPBAF010000000
VERSION     DAPBAF010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 605)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 605)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..605
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.167"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            1..101
                     /locus_tag="RD451_002938"
                     /pseudo
     CDS             1..101
                     /locus_tag="RD451_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012655884.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="APH(2'')-If/Ih family aminoglycoside
                     O-phosphotransferase"
     gene            85..477
                     /locus_tag="RD451_002939"
     CDS             85..477
                     /locus_tag="RD451_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7568104.1"
                     /translation="MKLLFIDDNMVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCY
                     TLLRPDGKTMFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRA
                     CHVYEKLGGKNDYKDEIVYVYDYEKGDK"
BASE COUNT          247 a           40 c          104 g          214 t
ORIGIN      
        1 gagaagatat attaagaatg tatggaaata tagatattga gaaagcaaaa gaatatcaag
       61 atatagttga agaatattat cctattgaaa ctattgttta ttgatgataa tatggttttt
      121 gatattgata atttaaaagg atttcttaat gataccagtt catttgggtt tatagctaaa
      181 gaaaataata aaattatagg atttgcatat tgctatacac ttttaagacc tgatggaaaa
      241 acaatgtttt atttacactc aataggaatg ttacctaact atcaagacaa aggttatggt
      301 tcaaaattat tatcttttat taaggaatat tctaaagaga ttggttgttc tgaaatgttt
      361 ttaataactg ataaaggtaa tcctagagct tgccatgtat atgaaaaatt aggtggtaaa
      421 aatgattata aagatgaaat agtatatgta tatgattatg aaaaaggtga taaataaatg
      481 aatatagttg aaaatgaaat atgtataaga actttaatag atgatgattt tcctttgatg
      541 ttaaaatggt taactgatga aagagtatta gaattttatg atggtagaga taaaaaatat
      601 acatt
//
LOCUS       DAPBAF010000154          602 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.168, whole genome shotgun sequence.
ACCESSION   DAPBAF010000154 DAPBAF010000000
VERSION     DAPBAF010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 602)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 602)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..602
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.168"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            <1..>602
                     /locus_tag="RD451_002940"
     CDS             <1..>602
                     /locus_tag="RD451_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDT7568105.1"
                     /translation="LARDSAMKYGIPLTLDTPYNQPGIKSHLWVTQNIWGDHTDPYGY
                     LSEMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAANPTLTDGTNYAHIDQFG
                     EIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIYRSDVNQAYNTSGNVGY
                     HVSFNMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRW"
BASE COUNT          206 a          109 c          124 g          163 t
ORIGIN      
        1 ttggctagag attcagcaat gaaatatggt attccattaa cgttggacac tccttataac
       61 caaccgggaa tcaaatcgca tttatgggta acacaaaaca tctggggcga tcatacagat
      121 ccttacggtt atctttctga aatgggcgta agtaaagaaa aattagcata tgatttagct
      181 catggattta ccgatgaaaa tccaacaact tctgaaaaca agcctgtcat tgatccaaca
      241 cgagctggtg cagctaatcc tacactgaca gatggaacga attacgccca cattgatcag
      301 tttggagaaa tcgaaaatgc aaatttgcat gtagctggat ggcacattgc taactataaa
      361 tacgagtata tcttcattat ggattacaat actgggaaag aattagctcg agtaagagct
      421 gatggaattt atagatcaga tgtaaatcaa gcttataata cttctggaaa tgttggctat
      481 catgtatctt ttaacatgcg taacttccct aataagaaag tctatgtcat gatgcgggca
      541 acgaatgatc cagagggaaa cactaaaggc ggtgcgcaag atttccatga caaacgttgg
      601 ta
//
LOCUS       DAPBAF010000155          593 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.169, whole genome shotgun sequence.
ACCESSION   DAPBAF010000155 DAPBAF010000000
VERSION     DAPBAF010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 593)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 593)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..593
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.169"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            <1..580
                     /locus_tag="RD451_002941"
     CDS             <1..580
                     /locus_tag="RD451_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDT7568106.1"
                     /translation="GIKSHLWVTQNIWGDHTDPCGYLSEMGVSKEKLAYDLAHGFTDD
                     NPTTSDDNPTTSEDKPVIDPTRAGAANSTLTDGTNYAHVDQFGEIENANLHVAGWHIA
                     NYKYEYIFIMDYNTGKELARVRADGIYRPDVNQAYNTLGNVGYHVSFNMRDFPNKKVY
                     VMMRATNDPEGNTKGGAQDFHDKRWYLNIPQR"
BASE COUNT          204 a          105 c          122 g          162 t
ORIGIN      
        1 aggaatcaaa tcgcatttat gggtaacaca aaatatttgg ggcgatcata cagatccttg
       61 cggttatctt tctgaaatgg gtgtaagtaa agaaaaacta gcctatgatt tggctcatgg
      121 ttttacggat gataatccaa ctacttcgga tgataatcca actacttcgg aggataaacc
      181 agtaattgat ccaactcgag caggtgctgc aaattctacg ctgacagatg gaacaaatta
      241 cgcccacgtt gatcagttcg gagaaatcga aaacgcaaac ttgcatgtag ctggatggca
      301 cattgctaat tataaatacg agtatatttt cattatggac tacaatactg gaaaagaact
      361 agctagagta agagctgatg ggatttatag accagacgta aatcaagctt ataatacttt
      421 aggaaatgtt ggctatcatg tatctttcaa tatgcgtgat ttccctaata agaaagtata
      481 cgtcatgatg cgtgcgacaa acgatccaga aggaaatact aagggtggag cacaagattt
      541 tcatgacaag cgttggtatt taaatattcc acaacgataa aaaattcccc cct
//
LOCUS       DAPBAF010000156          591 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.170, whole genome shotgun sequence.
ACCESSION   DAPBAF010000156 DAPBAF010000000
VERSION     DAPBAF010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 591)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 591)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..591
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.170"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(316..579)
                     /locus_tag="RD451_002942"
     CDS             complement(316..579)
                     /locus_tag="RD451_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uberolysin/carnocyclin family circular
                     bacteriocin"
                     /protein_id="HDT7568107.1"
                     /translation="MKKNLLLVLPILGFAGFFVGVPMLSANIGISSYAAKKVIDIINT
                     GSTVATIISIVAAVVGGGLITAGIVATAKSLIKKYGAKYAAAW"
BASE COUNT          224 a          103 c           78 g          186 t
ORIGIN      
        1 cttccttttt tgtatggatt ttttcattta cacaaaatat tttatactct cctgaatttt
       61 ttcatgttga aaacatcact aatcaaaggc aaattataat ttagaaatag aatgaaaaca
      121 ctaaatgaaa atagaacatt agaaaaaata gaatcaaaaa aacccaagac tagtgccgaa
      181 ataagggaaa caatcgaagc tacaaaaaat aatgatttcg ttgaacagga ccaatttatt
      241 tgtttccgat atttctcaaa aagaactttc tttgggaaag ttaaaggcga ctgtaaagtc
      301 gcctttagtc cttttttacc aagctgctgc atatttagct ccatattttt taattaatga
      361 tttggctgta gcaacaatac cagctgtaat taatccgcct ccaacaactg cagcaacaat
      421 agaaatgatt gtagcaaccg tgctaccagt attaattatg tcaataactt ttttagctgc
      481 ataagaagaa attccaatgt tagcacttag cattggtaca ccaacaaaga atcccgcaaa
      541 acctaaaatt ggtaaaacta ataataaatt ctttttcata ataattcctc t
//
LOCUS       DAPBAF010000157          534 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.171, whole genome shotgun sequence.
ACCESSION   DAPBAF010000157 DAPBAF010000000
VERSION     DAPBAF010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..534
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.171"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            <1..>534
                     /locus_tag="RD451_002943"
     CDS             <1..>534
                     /locus_tag="RD451_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="HDT7568108.1"
                     /translation="GKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHTTIYR
                     WVQEYGKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWLRKK
                     RDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLNNL
                     IEQDHRPVKRRNKFYRS"
BASE COUNT          188 a           89 c          105 g          152 t
ORIGIN      
        1 aggaaagcaa tttcagcagg atgtgattat tgtagccgtg ggctactatc ttcgttataa
       61 ccttagctat cgtgaagttc aagaaatctt atatgatcgt ggcattaacg tttctcatac
      121 gacgatttat cgttgggtgc aagaatatgg caaactactc tatcaaattt ggaaaaagaa
      181 aaataaaaaa tccttttatt catggaaaat ggatgaaacg tacatcaaaa ttaaaggaaa
      241 atggcattat ttgtatcgag ccatcgatgc agatggttta accttggata tttggttacg
      301 taaaaaacgg gacacacaag cagcctatgc ttttcttaag cggttagtga agcagtttga
      361 tgaaccgaag gttgtagtca cagataaagc cccctctatt acaagtgcct ttaagaaact
      421 aaaagaatac ggcttttatc aagggacaga acatcgtacc attaaatacc tgaataattt
      481 gattgaacaa gaccatcgtc cagtaaagag acgcaataaa ttctatcgaa gttt
//
LOCUS       DAPBAF010000158          509 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.172, whole genome shotgun sequence.
ACCESSION   DAPBAF010000158 DAPBAF010000000
VERSION     DAPBAF010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 509)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 509)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..509
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.172"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
BASE COUNT          228 a           70 c           81 g          130 t
ORIGIN      
        1 aattccttag gcagcttttg ctgtgtagaa aggaataaat aataacgaaa gttcaaaagc
       61 taatgccgac tattctagac attaaagaag acgaaaacga acgataaaga aagaaaagtt
      121 atgaataatc gtttattgaa aaaaacttga aaaaatacaa aaaattcgtt gaccaagcta
      181 aatttagttg gtatattatt acttgtccaa aagacagaag aaaatattta ttcaaaaaca
      241 taacaaaaaa gttattgaca tgttactaac gacatgataa gataactgag tcgttaaaaa
      301 agaaccactt gcgaagcttg attctatcga aaaaaacttc aaaaaagttc ttgacaaata
      361 acaaacgata agttatgata aatgagttgc cgaaagattt cgaaaaacga aatcgaaaaa
      421 aacttttaaa aaagagttga caatcgcttg tctctctgat atgatataaa agttgctacg
      481 gcagccaaaa atgaatcggg aaacactct
//
LOCUS       DAPBAF010000159          486 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.173, whole genome shotgun sequence.
ACCESSION   DAPBAF010000159 DAPBAF010000000
VERSION     DAPBAF010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 486)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.173"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(<1..411)
                     /locus_tag="RD451_002944"
     CDS             complement(<1..411)
                     /locus_tag="RD451_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7568109.1"
                     /translation="MGETGWRATTLNYQWPVAFSLLTFYPFFQLLRGEEINRKIYWVS
                     IPLLIFLTNQEQVNACFFVLTSIVSLYLIVNGRYNYKLSVFSIISLAELIFSLTTPGN
                     ALRAAHEINKWFPEYKNFNFLNKLDLGISSFGKPF"
BASE COUNT          183 a           78 c           62 g          163 t
ORIGIN      
        1 aaacggcttt ccaaatgatg aaatacctaa atctaactta ttaagaaagt tgaaattttt
       61 atattcagga aaccatttat taatttcatg tgcagcacgt aatgcattcc ctggagttgt
      121 caaagagaaa attaattctg ctaagcttat tattgaaaat actgataact tataattata
      181 tcgtccattg acaatcaaat ataaactaac tatacttgtt agaacaaaaa aacaggcgtt
      241 gacttgttct tgattagtta aaaatatcaa taaaggaata cttacccaat atatttttct
      301 atttatttct tctcctctta agagttgaaa aaacggataa aaagttagta aactaaatgc
      361 tactggccac tgatagttca aggtggttgc tctccaaccg gtttccccca ttactgtcaa
      421 tggtattaaa cagtatatag agcaaaccaa taataaattt ttaacattta ttttctcaaa
      481 aacata
//
LOCUS       DAPBAF010000160          479 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.174, whole genome shotgun sequence.
ACCESSION   DAPBAF010000160 DAPBAF010000000
VERSION     DAPBAF010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 479)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 479)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.174"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(<1..426)
                     /locus_tag="RD451_002945"
     CDS             complement(<1..426)
                     /locus_tag="RD451_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HDT7568110.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQ"
BASE COUNT          143 a          100 c           72 g          164 t
ORIGIN      
        1 ctgataaacc gttgataaat caattccatt ttggtcaatc ttattgataa aaaagattgt
       61 gggaatcccc attttcctaa gtgcatgaaa taatatacga gtttgtgctt gtacgccatc
      121 ttttgcagaa atcagtagaa ttgccccatc taaaactgat aatgaacgat atacttctgc
      181 taagaaatcc atatgtcctg gcgtgtctat gatgttcacc ttcgtatttt cccactgaaa
      241 agaggttatt cctgtctgaa ttgtaattcc tctctgacgt tctaaaagcg tattatccgt
      301 cctcgttgta cctttgtcca cgcttcctaa ttctgtaatc gctccactgt tatataataa
      361 gctttctgtt aaggtagttt ttcctgcatc aacatgagct aaaactccaa tattaataat
      421 tttcatgtga ttttcctcca ttcaaaaacc caaaagggca taaaaatccc agtgataaa
//
LOCUS       DAPBAF010000161          449 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.175, whole genome shotgun sequence.
ACCESSION   DAPBAF010000161 DAPBAF010000000
VERSION     DAPBAF010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 449)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.175"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(34..270)
                     /locus_tag="RD451_002946"
                     /pseudo
     CDS             complement(34..270)
                     /locus_tag="RD451_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          146 a           76 c           77 g          150 t
ORIGIN      
        1 agaaggactg accttctgtc tcagattttt ttgttatttc acttgaatca attgattgat
       61 caaaaaaatc ctgattttca tgttctcaaa tgatttaaat ccataagata atcgtttcag
      121 tgtcttgata tggggaatct tggcctctat tttgccatta gaatacgggt aaatcatagc
      181 attgtaaata ccttcttcat acgttaaaag gttttgaagt ttcgtgcgaa gttgtgcatc
      241 aagtgtttca ggaagatttt ttaataacgc cgtttgtata attaagcgag acaaataaaa
      301 aagccattta tgttacactc caattgtaat acccgctaaa gcatacaagg agagtgaaca
      361 taaatgactt atacccatct tacaccaaac gagcttgtaa tgatagaagc atattttcat
      421 caagaaactc cggttgctat cgttgcgaa
//
LOCUS       DAPBAF010000162          444 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.176, whole genome shotgun sequence.
ACCESSION   DAPBAF010000162 DAPBAF010000000
VERSION     DAPBAF010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 444)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 444)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..444
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.176"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            <1..379
                     /locus_tag="RD451_002947"
     CDS             <1..379
                     /locus_tag="RD451_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDT7568111.1"
                     /translation="HRLFKRPISQTEIVDELLSYNEELRTAYHFCQLLRYYFVKRGTE
                     GFQETLKTISSTLPQSFKKKFTIFHRYQSGISNAFKVSHSNGVTEGLNNKIKLIKRIA
                     FGYRNFYNFRARIYLQQGLIFEN"
BASE COUNT          141 a           93 c           80 g          130 t
ORIGIN      
        1 tcatcgactg tttaaacgac caattagtca aacagaaatc gttgatgagc tgttaagcta
       61 caacgaagaa ttgcgaactg cgtatcattt ttgtcaatta ttacgctatt atttcgttaa
      121 acgaggtacg gaaggctttc aagaaaccct taaaacaatt tcatctacgt tacctcagtc
      181 gtttaaaaag aaattcacga tcttccatcg ctaccaatcg ggtatttcaa atgcctttaa
      241 ggtgtcccac tcaaacggcg tcactgaggg gctgaataac aagatcaagc tgattaaacg
      301 aattgcgttt ggttatcgca acttttataa ctttcgggca cggatctatt tacaacaagg
      361 tctgatcttt gaaaactaaa aaaatatgcg gcgcacagaa cgcgccgcat atcggactaa
      421 gttttattca aatttgtctt cacc
//
LOCUS       DAPBAF010000163          430 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.177, whole genome shotgun sequence.
ACCESSION   DAPBAF010000163 DAPBAF010000000
VERSION     DAPBAF010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.177"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            <1..>430
                     /locus_tag="RD451_002948"
     CDS             <1..>430
                     /locus_tag="RD451_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HDT7568112.1"
                     /translation="QRATYRAVCSVLFPNGDFPSRSRFTRLSSNLAYTIKIIRYFFIK
                     KLTKGELVGIIDSFPSPLCKPVRNRQAKLLNQIAKVGYNSTKKSYFYGLKIHMIVTKT
                     GFPITYSITNPGVHDVKVLETLSEEANLPNILGDKGYISHK"
BASE COUNT          145 a           81 c           74 g          130 t
ORIGIN      
        1 caaagagcca cgtatagagc ggtttgttcc gtcttatttc ctaatggtga ctttcctagt
       61 aggagtcgat tcactcgctt aagttcaaac ttagcttaca ctatcaagat tattcgatac
      121 tttttcatca agaagctcac caaaggtgaa ctagtcggaa ttatagatag ttttcctagt
      181 ccattatgta aaccagttag aaatagacaa gcaaaactat tgaatcaaat agccaaagtt
      241 ggctataact caacaaaaaa atcttatttt tatggtctta aaattcatat gatcgttact
      301 aagactggct ttccgattac ttactcaatc acgaatccag gtgtccatga cgtgaaagtg
      361 ttagagactt tatcggaaga agcgaatctt cccaatatcc taggggacaa aggatatatt
      421 agccataaaa
//
LOCUS       DAPBAF010000164          430 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.178, whole genome shotgun sequence.
ACCESSION   DAPBAF010000164 DAPBAF010000000
VERSION     DAPBAF010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..430
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.178"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            <1..>430
                     /locus_tag="RD451_002949"
     CDS             <1..>430
                     /locus_tag="RD451_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS30-like element IS6770 family transposase"
                     /protein_id="HDT7568113.1"
                     /translation="LYRLFSKGIFDIDTLPMKGKRKPNGHQEKRGKQQYQRSIHDRPD
                     NYPDFNSEFGHLEGDTIVGIHHKSAVITLVERLSKVIITIKPNGRKALDIETALNQWF
                     SRFPKNFFKSITFDCGKEFSNWKAISNQHDIDIYFADPGTP"
BASE COUNT          143 a           84 c           73 g          130 t
ORIGIN      
        1 cactttatcg tttattttct aaaggaatat ttgatattga cacactaccg atgaaaggta
       61 aaagaaaacc caatggccat caggaaaaac ggggaaaaca acagtatcag cgctcaatcc
      121 atgatcgacc tgataattat cctgatttca attctgagtt tggtcacctt gaaggtgata
      181 cgatcgttgg cattcatcat aaaagtgccg tcattacttt agttgaaaga ttatctaaag
      241 tcattatcac gattaaaccc aacggccgta aggcattaga tattgaaact gcccttaatc
      301 aatggttttc tcgcttccct aaaaacttct ttaaatctat tacgtttgac tgtggaaaag
      361 aattttctaa ctggaaagcc attagtaacc aacatgatat tgatatatat tttgcggacc
      421 ctggaacacc
//
LOCUS       DAPBAF010000165          429 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.denovo.179, whole genome shotgun sequence.
ACCESSION   DAPBAF010000165 DAPBAF010000000
VERSION     DAPBAF010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 429)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 429)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..429
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.denovo.179"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            <1..>429
                     /locus_tag="RD451_002950"
     CDS             <1..>429
                     /locus_tag="RD451_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDT7568114.1"
                     /translation="KIPHFSTFGKNYVRRFRETTVFEDIFAYILEQAVKAGFVTEDNL
                     YLDSTHIKANANKHKFTKEMTHDEAKAYQDELEDEINRQRIEAGKRPFTLDLEKEVKL
                     KERKISKADPESGYYVKGEREKQFAYSAHTSCDDNGFILST"
BASE COUNT          157 a           75 c           88 g          109 t
ORIGIN      
        1 aaaatccccc atttctcaac ttttggaaag aattatgttc gccgatttag agaaacgacg
       61 gtgtttgagg atatttttgc ctatatttta gaacaagcag ttaaagcagg ttttgtaaca
      121 gaggataatt tgtatctgga ttctacccac atcaaagcta acgccaataa acataagttt
      181 acgaaagaaa tgacccatga tgaagcgaaa gcctatcagg atgaattaga agatgagatc
      241 aatcgtcaac gaatagaggc tggaaaacgc ccttttactt tggacttaga aaaggaagtg
      301 aagctgaaag aaagaaaaat aagtaaagct gatccggaaa gcggctacta cgtcaaaggc
      361 gaacgagaaa aacaatttgc ttattctgcc catacttcat gcgacgacaa tggatttatt
      421 cttagcaca
//
LOCUS       DAPBAF010000166        13213 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.guided.066, whole genome shotgun sequence.
ACCESSION   DAPBAF010000166 DAPBAF010000000
VERSION     DAPBAF010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13213)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13213)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13213
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.guided.066"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(204..2162)
                     /locus_tag="RD451_002951"
     CDS             complement(204..2162)
                     /locus_tag="RD451_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDT7568115.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAATRPAQTNTVVKTETFAGGTIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVKEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(2159..3031)
                     /locus_tag="RD451_002952"
     CDS             complement(2159..3031)
                     /locus_tag="RD451_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDT7568116.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            complement(3373..4245)
                     /locus_tag="RD451_002953"
     CDS             complement(3373..4245)
                     /locus_tag="RD451_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDT7568117.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKVFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            4373..4942
                     /locus_tag="RD451_002954"
     CDS             4373..4942
                     /locus_tag="RD451_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HDT7568118.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            5009..5746
                     /locus_tag="RD451_002955"
     CDS             5009..5746
                     /locus_tag="RD451_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDT7568119.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            5977..7245
                     /locus_tag="RD451_002956"
     CDS             5977..7245
                     /locus_tag="RD451_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HDT7568120.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            7732..8196
                     /locus_tag="RD451_002957"
     CDS             7732..8196
                     /locus_tag="RD451_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDT7568121.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIKH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            8180..8809
                     /locus_tag="RD451_002958"
     CDS             8180..8809
                     /locus_tag="RD451_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDT7568122.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMKPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITMFE"
     gene            9163..10641
                     /gene="msr(C)"
                     /locus_tag="RD451_002959"
     CDS             9163..10641
                     /gene="msr(C)"
                     /locus_tag="RD451_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HDT7568123.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRLDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            10688..11134
                     /locus_tag="RD451_002960"
     CDS             10688..11134
                     /locus_tag="RD451_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HDT7568124.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(11333..11848)
                     /locus_tag="RD451_002961"
     CDS             complement(11333..11848)
                     /locus_tag="RD451_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HDT7568125.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            11965..13167
                     /locus_tag="RD451_002962"
     CDS             11965..13167
                     /locus_tag="RD451_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDT7568126.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
BASE COUNT         4116 a         2424 c         2708 g         3965 t
ORIGIN      
        1 agaggttgta aaaaagctgt tctgcatcaa gtaataagaa gagtcaaata aaaaatagct
       61 cttcatatgt tacgtttggc tggacttatt accgcggagt tggcaggaga acgccgtttt
      121 tattcggaaa aaggagctga gacaagattt ttgtctcagc tcctgtttgt ttatcgataa
      181 aaaagtctgg ggaagacgat ggctcaggct ttgttggaaa cagagccgat tttatcattt
      241 gcttttacat cacgtgcggg ttcgatttct aagctttgga ctttgtcgcc atttgtgaat
      301 acaacgacca tatccgtgtt tttgcctgca gattgaatag cggcaagatc aactaaagca
      361 atcaattgac ctcttgcgac tttttgacct tcttttacat ataaagtgaa tggttcgcct
      421 tttaagtcaa cagtgttgat gcccatatga agcaagactt cgataccagc atctgtttgg
      481 attccgacag catgtttcgt tgggaaaatg tttgtgatcg taccagcgat tggagagaag
      541 atttctccat tttctggtaa tacagcatag ccgtcaccca tcattttttc cgcgaataca
      601 tcatctgaaa cttcagtgat tggaatcagt ttcccatttg cgatagcgta aatatcttgt
      661 tcgatcgttc caccggcaaa tgtttctgtt ttaaccacgg tgtttgtttg tgcaggtcgt
      721 gttgcagcac caccatgtag ttttgccatc tcatctgcaa cgaattgtac ttctgtacct
      781 acgatgactt gcgcattttt tccgtcgatg atcttcatac caggtacgcc agtggctttg
      841 attttatttt gatcgatcag gcctgtatct ttgacttgca aacgaaggcg tgtagtacag
      901 ttatcgatcg aagttacatt gtcggctccg cctaatgcag cgtagatttt gcttgcttgt
      961 gccgcatatt tattgtctga attagtcgtt gcagtatcgt catctgaaag atctgcttcc
     1021 tcgcggccag gagtcatcag atggaatttt ttgatagcaa agttaaagcc aaagtagtaa
     1081 atcactgctg ttactaatcc ttggacgatc aacatcaatg gctgattcgc aatcggattt
     1141 ttcaaagata ggaagtaatc gacaaatccg gcactaaagg caaatcctgc tgtccaatgg
     1201 aagaatgcac tcactgctaa agaaatccca gtgaaaattg catgcaagac atataatggc
     1261 caagcaacga acataaatga gaattcaagt ggttctgtta caccagtaaa gaatgaagca
     1321 aaagctgctg ctaacatcaa ggaagctgtt tttgctttgt tttctggacg tgcatttctg
     1381 taaatagcat atgctcctgc tggaagcccg aacatcatga ttgggaaaaa tccagcttga
     1441 tacattcctg ttacgccttt tgttccttca gaagccaaaa atttaccaat atcattgatt
     1501 cctgctacgt caaaccagaa cacggagttc attgcttgat gcaatcctgt agggatcagt
     1561 aaacggttga agaagccata aagacctgca ccaccccagc ctaaactcaa aatgaattta
     1621 gcaaaagaaa ctaaagcaga gtaaaccgga ggccatacga gcagtagcac tgcactgatc
     1681 agcaacatga caaaggcagc caagattggc actagacgct tgccgctaaa gaaagataaa
     1741 gccatcggta attttgcttc gtggaaacga ttataaagag ctgccgcaat caatccggca
     1801 ataataccaa taaatacgtt actgatctga gcaaaagatg gatcaactga ttctggtttg
     1861 atattcaata aagtagctac tgaatcagtt tttaaaacat ttactggaac ttcaaatgcg
     1921 accaaacctg ccaaggcagc agcacctgat ttgtccactg acatccctag tgctaaccca
     1981 acggcaaaca gcaaaggtaa ttgacctaaa actgcgttac cgccagcttg taaaaaatga
     2041 gcgacaatgt cgttactata agatgcccac cagtttccga tccctactag taaagcagca
     2101 gcaggtaaga ccgcaactgg aagttgaagg gaacgtccca ttcgttgtag atatgctttc
     2161 aatttttttc ctcctcatga ttgttaacat ttgtttgtac gattgcgctt cttaaacgct
     2221 cgatatggat ggccaagtaa cccagttctt ctttcgtgat cgcgagctgg tattctttgg
     2281 tcagcaacac acggattttt ttagaaatct tatagctttc tgggtatttt cgtttgacca
     2341 tttctacgat ttccgtgtct aaaacagcat attgttgcgc atgggttcgt tgtagaagca
     2401 gtcgtaaatg attcaccagt cttgaataat tcagtgaaaa tggttctgaa tggatatctg
     2461 tttccaattc tgattccact aaatggatga tgtcagatac aatcgtcact tcacggatac
     2521 tgcgatggtt attgttccga ccgcttcgtc cgctgtgaat atggattgcg atatatcctg
     2581 cttcgtcata agtatatgga atcccaagct cttttgtcag atactctact gcccattgag
     2641 caatactgaa ttcatcactg taaagcactt cgatttctct taaaagtttg ttgcggatga
     2701 cgataccgtt attaatgttc tccgcagaaa aagcaatgtg gtcggtcaaa gcgatcaata
     2761 catgttcatt caacttttcc atcaaaacag tttccgcatg atcaatgatc gtttctgctg
     2821 caaataaaaa gcgttcatca atctgattaa gtaaattttg caacttgatt tgaccttctg
     2881 gttccatgac aaatatccgt tcgacatcac gatcaaaaat caaatcattt ctttttctgt
     2941 caaatccaat cccttttcca atagctactt tttcctgtcc accgtcatct accaatactg
     3001 cattttgatt aaagatcttt ttgattttca tgcgcgcacc ctttttgaag atttggtttt
     3061 cacgtttgct agaccagttg attgcggcca aacaaaaata gacacgaaaa acctcctagg
     3121 gaaaccatgt tcctcagaga tttttcatgc ctagtatgat ctagtcacat gaaacgaatt
     3181 attgttaacg taatcaattt tatatagaca gttatgtttt gtcaattctt tttttataat
     3241 tatagtaatt tactggaatt atcagaaata aaaggaagga acaaattaag aaacttatgt
     3301 tatttaatca ttggatcttt tgcttaactt attcgttgtt aaaaagctga aagcgaagga
     3361 aaaaaactct acttaactgt atttctccgt taggacatct aaaaatttac gagcagcagg
     3421 agaaagaggc tggtcttttt tccaaatgag attcagtgaa gcttgtaatg gcggatcgag
     3481 tgggatgaat actttttccg tcccataagt attgatgatc ccatctagag ctaatgcacc
     3541 aaaagtcccg ttatcgacca tcaaagaagc attgtacaat aagttatatg ttccgacgat
     3601 cgataactga tctatgctga aacctagcca ttcagctagt tgactgtcca ctgacgtttg
     3661 ccgggaaatg atcaaaggaa cagttttcag ttcctgcgga tggatgactg tttgctttgc
     3721 taaaggatga ttccgatgta tcaaaagtcc ccaacgatct tgggctggca gtcgaaatga
     3781 ctggtatttt tgtttgtttg tcggttcgat tacgagtcca aaatcaagta atccgctatc
     3841 cagtttgtct atgatatcat ctgcattccc gctatataaa tgaaactgga tatcaggatg
     3901 cgccttgatc aacgaatgaa ggctatcaga aatgaaagag attgctttag tttcgcctcc
     3961 gccaatgtag atttctccag agatgattgc gtcatttgtt aaattgttcg ccgttttttc
     4021 taccaacgac aagatttctt ttccttttga ataaagatat cgaccagaat ccgtcaactg
     4081 tatctctcgg gagcctcgag tgaaaagtgt cacaccaagt tcttcttcta aatctttcag
     4141 ttgttttgag agagtaggtt gcgtgatatg cagagatttt gctgctcggc tgatattttt
     4201 ttctctagct actgctaaaa aatacgtcag tatacgaata tccatttttt ccctcctgtt
     4261 tttaaaaaag cataccacta agtatagtta aaaggaatag ttaagtatgt tttataagta
     4321 ttagacatca taagccgtcc gttataaagt aaggataaaa ggagggagca aaatgacaag
     4381 cctcatcgaa aaacaaatcg tcaataaaga gattcgagta acggatccgc tctttgaagt
     4441 gatccatcag atccaagcgg aaaacgaaga gcctttagca gcgctgaata ctgggtacca
     4501 tgaaccagca gatatccgca aacggctaga aaatatcatt agtgacaaag tagatgatac
     4561 ggtgactgtt ctgctgcctt tttatacaga tttcggcaaa catattagta tagggaaaaa
     4621 tgtctttatc aatcgtcaag tgatgttcgt tgacttaggt ggcatctgtt tagaagattc
     4681 agtattgatt ggtcctcgtg tcaacctcat cacggtgaac catctaaccg atccaaaaga
     4741 acgaagaggc ttgtcagtaa agccaatcca catcaagaaa aatgcttgga tcggagcagg
     4801 agcaactatt ctgccaggcg taacgattgg cgagaatgcc attgttgcag cgaatgcaac
     4861 tgttacgaaa gatgtcccag acaataccat cgttgcagga atccctgcca aaatcgtcaa
     4921 acctgtcgaa cggattattt gaacagtaag atgaaataag agatagtgag tataagcaag
     4981 agatttttca aaacaggagg agaatagaat gaatgattta tcagaaaaag tgattgtcat
     5041 catgggcgct tcaagcggaa tcggtgaagc aacaacgaag ctattagcag aaaaaggggc
     5101 taaactagtt atagctgcac gccgagaaga tcgcctaaaa gcaataaaag aatctttacc
     5161 agaagctgag ctatatattc aaacagcaga tgtaagagat tttgcacaag tccaagcagt
     5221 tatcgattta gcgatggaaa agttcggtcg aatcgatgta ttgtacaata atgcaggaat
     5281 catgccaacc gctccattag ttgaaggtca ccgtgatgaa tggcaaaata tgcttgatat
     5341 caacatcatg ggtgtgttaa atggaatttc cgccgtactt ccaatcatgg aaaaacaaaa
     5401 atctgggcat atcatttcaa ctgattctgt ggcgggacat gttgtttatc ctgattccgc
     5461 cgtttattgc ggaacaaaat ttgctgtccg tgcaatcatg gaaggattac gtcaagagca
     5521 acggcaaaat aacatcaaat ctacgatcat ctctccagga gctgttcaaa ctgaattata
     5581 tcaaaccatc agcgacaaaa aggctgctct tgaacttcat gaagcgcaaa aagaatgggg
     5641 attaacatct gaagatatag cttctgctgt agcatttgcg atagaaacgc cagaccggat
     5701 gtctgtcagc aacatgatta tccgtccgac gacacaggaa gtataatcca taacggataa
     5761 tatccagaga gaattacttg ttaaatagtt attcaaacga ccatcaattt aaggcgtgaa
     5821 tggagaagaa tattcttcat ttacgtcttt ttatgcagaa aaagcaaatt tattaaaaag
     5881 aaacaaatgt tatttaaata tggacattga cttgctttta cttttttagt tacactgtta
     5941 tttaggaaaa gtttcataat tcaaaggaga aaaaagatga aagcaaagaa tttattattt
     6001 agcgttattc ttttaggaaa tctagcagtt gccaacacaa cagtgctagc tgaagaatcg
     6061 acagaaactg tcgcaactca gacatcgagt tcttcagaaa caggaattga aaacgataca
     6121 gaaagtactt tgcagtcagc tactgtctca gaaaatacaa tttcaaccga agaaccaaca
     6181 actgaaacaa cagaacaaac acaaaccgaa gacagtacat cagcagaagc tcagaacaat
     6241 ccagagaatg cagaagaaat cacgaaccaa ttgacagatg ggcaaacatt gacacatacc
     6301 catcaagcag atttgtctga attcgaaaac tatactggct atgcttttta tgctcgctca
     6361 tctgctaatt ctcaacaagc gttcattgat agtattgcct caactgcaca aagtttggca
     6421 agtgccaatg acttatatgc atcagtcatg attgctcaag ccatcgttga aagtggctgg
     6481 gggaacagta ctttggcttc tgcccctaat tacaatctat ttgggattaa aggaagctat
     6541 aatggccaat ctgttacgat gcctacttcg gaatatgtga atgggcaatg gattacggtg
     6601 aatgccgctt ttagaaaata tccttcgtac aaagaatcat tgcaagataa cgtaacggta
     6661 ttgaagacga cttcttttca gccaggcgtt tactactatt ccggtgcatg gaaaagcaat
     6721 acgaactctt acaaagatgc tacggcttgg ctaacaggtc gttatgccac tgcgcctaat
     6781 tatggttcta cattgaacaa tgtaatcgaa acctataatc tgacacagta tgatacagca
     6841 ccaacttcaa cttctccgat gtatcgtctg tataaccgtc atacaggaga acatttatat
     6901 acattgaatg ccggagaaaa aaattatctg ccaactgtag gctgggaata tgaagggatt
     6961 gcttggcaag caccaaacag cggacaacct gtctaccgtt tatacaatcc ttacagtgga
     7021 gaccatcatt acacaatggc acaatctgag atcaactctt taacaaaaat cggttggcgt
     7081 tatgaaggtc taagttttta ttctggtggt tccaagccaa tttatcgact atttaatcca
     7141 aatgaaaaaa ctggtaccca tcactatacc ttgagtgcta aggaaagaga ttggctaaca
     7201 ccgatgggct ggagatatga aggaatagga ttttatggtt attaaaaaga ggtagtgaaa
     7261 aagctgccct gcatcaagta gtaagaacag ccaaacaaaa acagattttc atgttttttg
     7321 tttggttgaa cttattaccg cagatgcaag tttttgaaca ccgtttactc aaaaaaggtt
     7381 gtgacaacat cttgtcataa cttttttatt actgtttaag catactgatc caatttctaa
     7441 tattcgacgg gattcttgca aaaggcgatt tcggaaattt ttggcggtgt aaaattatct
     7501 actgcagaag agctatcttc tatagtttga taagaatcaa taatcttggt tttagcgttg
     7561 tgctttcttt atcatttttt ccgttcattc tacaaaaaat ttcttttctc tatacttttc
     7621 tattgagagc gtttttttta ttacacagct gattctttga cttttttctt tttttattct
     7681 attattgaca agtcaatcgt tgacgagtca attattagaa aggaggaaat tatgtcttta
     7741 gaagagatta gtcacctttt atatcaaatc aaattagccg atcaaaaaat cgtccagatc
     7801 tttgaagaaa atatcggtat aagtcttact agatacgaga tcatgatgag actgaaagaa
     7861 gaaaatccat tgctacaaag cagtttgcaa gaaaagttgc agattgatca aggagcagtt
     7921 actcgtcatc tgaaggtatt ggaagcaaat ggctatgttt cgcgtcagag aaatcctcag
     7981 aacaaccggg aagtgtatgt agcgctaaca gaaaaagccc agaagaaaat caagcattgt
     8041 gaaatggacc ataaagatac aggttccgtg ctatccccgg ctttcagcga tgtagaaatg
     8101 aaacaatttc taacactttt agataaattg aatacccaac tttgcaatat aacaacagaa
     8161 acgaaagagg ttaataataa tggaacaaaa aaatgatttt tcaacaatta tgactggtag
     8221 aagatccgtt cgcgtatatg atgaaacata caaaatccca cacgaagaaa tgctggaaat
     8281 gatcaaagaa gcgacgactg caccttcttc tgtcaatatg aaaccatggc gctttgtggt
     8341 cgctgaaagc gaggaagcaa aagaaatctt gcgtcctttg atccgtttca atacgagaca
     8401 aaatgatact tcttctgcaa tggtcatgat ttttggcgat atgcaatgtt acgaatatgg
     8461 cgaagaaatc tacaaccaag cttacgaatc agggaagatg ccaaaagaag tcagagatca
     8521 acaattagct gcgatcattc cttattacaa gagtttttca agagaagaaa tgaacgatgt
     8581 agtcaaagtc gattctagct tagcggctat gcaattcatg ttagttgcgc gtgatcatgg
     8641 ctatgaaaca aatccaattg gtggattcga agcagatcag ttggcagagg catttggttt
     8701 ggataaagac cgttatgttc cagttattat tttatcaata ggaaaagcgg tagaagaagg
     8761 ttacgagtct gttcgtttag caccagaaaa gatcactatg ttcgaataaa aggttttcag
     8821 ttactattca gtagctattg ctttttttga atcgtgtgtg gtaacctaat aaaaaaggag
     8881 gtcggaaaaa tgactgcatc gatgaaatta cgtttcgaac ttttgaataa caactaaata
     8941 aattcaaaag acatgtataa acaacaattt catggatgga gtatgtccat tttttcgaac
     9001 gacagtagaa taggtgaaag ctatgacaga tttggtgatt tagtcatagt tatttcgttc
     9061 agagtaggaa aagatgtgat gcagtttttt tgcaaacaga tttttctgct cttttttagt
     9121 atcgataatt gttgttttac atgaaatagg agtgtaaaac atatggaaaa tttagcagta
     9181 aatataacaa atctacaagt cagctttggc aaccagctag aactatctat tgattctctt
     9241 cgtgtctatc agcaagatcg tatagggatc ataggagaaa atggtgtcgg taaatcgact
     9301 ttgctcaaac taatagccgg tgaacttttt cccgatcatg ggaaaatcca aacagagatc
     9361 accttcaact acctgcctca attaacctat ctcgctgaag caaaggacct aaatttggaa
     9421 ttagccagtc atttccagtt aagactggaa gaaacttcag agcggaaatg gagcggaggg
     9481 gaagaacgaa agatcgagtt gatacgtctt ctttcttctt atgaacaagg gatgcttcta
     9541 gacgagccaa caacccatct agatagaaaa agtattgatc gactgattga agagcttcgt
     9601 tattattatg gtacgctggt ttttgttagt catgatcgct attttctaga tgagctagca
     9661 tcgaaaatct gggaagtaaa agacggagaa atccgagagt tttcggggaa ttatagtgcc
     9721 tatctcactc aaaaggaatt ggagaaaaag actcagctac gagaagcaga gtcgatcatg
     9781 aaagagaaaa aacgattgga aaaatcgatc caagaaaaga aaaaacaagc ggaaaagttg
     9841 gaaaaagtgt ccagtaaaaa gaaaaagcaa caaatcagac tggatcggtt gtcttcctct
     9901 aaacaaaaag acagtgtaca aaaagccatc caaaagaatg cgaaaacatt agagagaaga
     9961 ctccaaaaaa taggagaaac aaccaagccg cagcagatga aacaaatccg ttttccagta
    10021 ccaaaatctc ttgaactcca cagccgctat cccatcatgg gacaaaatgt ccaattggaa
    10081 agaagtggga gaacattact ggtaaatggt gattttcagt tttctttagg taaaaaaatc
    10141 gcgattgtcg gtgaaaatgg ttcaggtaag acaaccttat tagaacatat ccgcaaacaa
    10201 ggagaaggaa tccttctctc tccgaaagta agctttcaag tatatcagca aaagggttat
    10261 caaatgacat ctgaagaatc catcattcgt tttgtcatga gacaaacaga gttttcagaa
    10321 tcgcttgtcc gtagtttgct gaatcactta gggtttgctc aggaaacttt gacgaaaccg
    10381 ttatgtacat taagtggggg agaagcgacc cgtctgacga ttgctttgct ttttactaag
    10441 ccaagtaatg tgttgctgtt agatgaaccg actaatttta ttgatatggc aacgatcgaa
    10501 gctttagaga agctaatgca aatatatccg ggaacgattt tgtttacttc tcatgattct
    10561 tactttgtcg agcgtacggc tgatgaagtt tatgaaataa aagggcagaa aataaaaaaa
    10621 gtacttacga gaaattttta aatgtgctac gatgattttc gtgacaaatt taaaggagtg
    10681 gtacagattg cctacaaata aaaaagaagg aataattttt acaacaatga tgtgtttttt
    10741 gatggtcttg gggatgagcg cgtataattt atggctgcat caagatcttc atttatcaag
    10801 tttgttgatt ggtctagtgc ctggattcgt ggtggctttc attttggatg tcttcatcat
    10861 cggtgtgctg gcgaaaaaaa ttgcctttaa actaccagta aatccagaaa gcaaggtcca
    10921 aatgatctta actatttcat gcttgatggt tttaggaatg gtgacatgta tgtctttatt
    10981 cggtgtgatc atggaacaag gaatacctga tcaattattc tctgcttata tgaatgcttg
    11041 gaaaatgaat gtgattgccg ctttaccgtt gcagttgatc atcgttggcc cgctttcaag
    11101 aagtgtgcta aaagcaattc aaagtaatga atgatggaac actgttattt gaaaaaaggc
    11161 cttggcatgc tttttgtcat agtctcttga atgcagttct agaaaaatag tgatccgaac
    11221 gataggtttt ggcctgtcgt tcggatcgct ttttcttttc caactgtatt gctcttttat
    11281 tgaagataat ttgctcttca atagatattt ctagaaaggt tctgtttatc ccttactcaa
    11341 aaaactgctg catttgttct cttacttgct gacaccattg gagttcctgc tgacaaagca
    11401 taattctgcg ctggatcaca acataacgtc caaattcttg tttcttgtct agcgagaggt
    11461 cattcaattt tttttgattt ttttgcatga ttttgttcag ctgttgttct ctagtgaata
    11521 gcagtccagt agctgttgtt ttatcgagcg tcgaaaaagc atagattttt gctagaaatt
    11581 catctttttg cgtaggagcg ggagtttcct ctttgatcca ttcctctaca agagcacgtc
    11641 cttcatcagt caagtggtag atcttttttt gagagtgctc gtctttgtcc aaaacggtca
    11701 cataaccctg ctggtctaac ttggcaagcg ttgtatagat ctgactgtga tgggcttccc
    11761 aaaaaattgt gatcagctgc ttcaattcat acccagaacg tggtttggat aaaagcacgc
    11821 ataataatat ataggctaaa gtattcataa aaatcctacc tctcgtctta ttttctttat
    11881 tatatcacag taaagtttcc acgttttaca tgtgcatatt gacatgtaaa ataaatcatg
    11941 tatgatgcta atagagagaa agggatggaa atattggaga atcaaataga tatacaagaa
    12001 caaacaaatg aagaaacaaa ggggaaaagt tcagcgctag ttgtagcagc tacctgtatg
    12061 atcgctttta tgggagtggg tctagtagac ccaatcttaa aaacgattgc tgcacagtta
    12121 aacgctacgc cagctgaaac gaccctgtta tttactagtt acatgttagt cactggtgtg
    12181 gtgatgctat ttacaggttt cttatctagt cggatcggtt tgaaaaaaac attgatgaca
    12241 ggattgttta tcatcgttgt attcgctggt cttggcggat tatctgggaa tatcggaatg
    12301 ctgattgggt tacgtgccgg ctggggtgtc gggaatgctt tatttgtctc tactgcttta
    12361 gcaacgatcg tcagtatttt agttggtaac acagaaaaag caatcatgat gtatgaagca
    12421 gcacttggct gcggaatggc tgttggccct ctagtcggtg gggtcttggg cagtggttca
    12481 tggcgttatc cattttttgg ggtagcattt ttgatgtttt gcggttttat agccctagcg
    12541 gtacttttac ctgaaactga gaaaccaaag agaaaagtag gcctttggga aggtgtcaaa
    12601 gcgttaagca atcataaact tcgttcagtt ggactaatcg cattgttata taatttcgga
    12661 ttctttactt tacttgcgta tgcgccattt ttattgattg gctattctga attagaagtc
    12721 ggttttgtat tttttggctg gggtgtgctt ctggctattg cttcgatttt cgttgcaccg
    12781 gctcttgagc ggaagtttac gacttatcgg acaattttag cagcatttgt cttattcatt
    12841 atttgtttgc tgttattagg agctggaact tctatgccag tccttgtacc gatcagcatt
    12901 gtgttagcag gatttttcca aggaattatc aatacactgt tgacgacgat tgctatggaa
    12961 ataccaggtc tgcaacgaaa cgttgcttcg tccagctata gttttgtccg ctttttcggt
    13021 ggagctttag caccatttat tgcaggtgtg attggtgaac atattggtga aagctatgcg
    13081 ttttattttg caggtgccat tgttcttatc agtgtatgtt gtatcattta tcaccgtaat
    13141 tattttgcta caaatgaaga agaataagaa atcagaggtt gtgaaaaagc tgtcctgcat
    13201 caagtcataa gaa
//
LOCUS       DAPBAF010000167        11516 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.guided.071, whole genome shotgun sequence.
ACCESSION   DAPBAF010000167 DAPBAF010000000
VERSION     DAPBAF010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11516)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11516)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11516
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.guided.071"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(134..577)
                     /locus_tag="RD451_002963"
     CDS             complement(134..577)
                     /locus_tag="RD451_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HDT7568127.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(795..2135)
                     /locus_tag="RD451_002964"
     CDS             complement(795..2135)
                     /locus_tag="RD451_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDT7568128.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            2404..3300
                     /locus_tag="RD451_002965"
     CDS             2404..3300
                     /locus_tag="RD451_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HDT7568129.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            complement(3450..4391)
                     /locus_tag="RD451_002966"
     CDS             complement(3450..4391)
                     /locus_tag="RD451_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HDT7568130.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            4517..5638
                     /locus_tag="RD451_002967"
     CDS             4517..5638
                     /locus_tag="RD451_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HDT7568131.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            5896..7398
                     /gene="eat(A)"
                     /locus_tag="RD451_002968"
     CDS             5896..7398
                     /gene="eat(A)"
                     /locus_tag="RD451_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HDT7568132.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            7426..7992
                     /locus_tag="RD451_002969"
     CDS             7426..7992
                     /locus_tag="RD451_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HDT7568133.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
     gene            8203..9264
                     /locus_tag="RD451_002970"
     CDS             8203..9264
                     /locus_tag="RD451_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HDT7568134.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            9267..10163
                     /gene="murQ"
                     /locus_tag="RD451_002971"
     CDS             9267..10163
                     /gene="murQ"
                     /locus_tag="RD451_002971"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HDT7568135.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            10177..>11516
                     /locus_tag="RD451_002972"
     CDS             10177..>11516
                     /locus_tag="RD451_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDT7568136.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAAL"
BASE COUNT         3817 a         2106 c         2400 g         3193 t
ORIGIN      
        1 ctgttcttat tacttgatgc agggcagctt tttcacaacc ccttattcac ggcgttccag
       61 aagtagcttc ttcttatttc ttgaagctga taacttctgg aacatcctct ttttttattt
      121 ggacggataa tggtcattcc atttctttga tcattttttt cattttgtcg atctcttctt
      181 cttgtgcctg aatgatttct tccgctaatt tttttacttc aggatctttt aaatcagctc
      241 gtttacttgc caggatagcg atagaatgat gaggaatcat ggccttcatc caagctgtgt
      301 cgttgacagt agtttggctt cgtaccataa acaaggaacc ggcaaaaaca agaagactag
      361 cggctaagat cataacattt atctttttgt tttcatacat tttccacatg aacaacagca
      421 tgatgactgc catgactgca cccatcatca acgccatgaa tactcgtgta cgactgaaga
      481 agatatgatc gagcgcatag acattcaagt acatcatacc aaacataact accgttgaaa
      541 caccgatcat caacaaaaac ttccaatact ttttcattta aaacaaactc ctttttttca
      601 ttcctttctt ctatcatgtc atgagcatgg agaacaatca attattttgc acagagggtt
      661 tttgaacacc gtttaccaag aggtcatgag actgtttatt cggaaaaagg agttgcaaca
      721 agacttttgt cacaactcct ttcttcaata gctccatcta ttccacataa ataaaataaa
      781 attttctatc gatttcattc attcgtcaat acgaacgcat cattcttttt ttgataactg
      841 aaataaatga acaggtaaag caggccagtc aatacagtta ccccaatgga gttcgtgaac
      901 aggataccaa ggaaaatcaa tcctaagaca gctaatgcaa aaaagctgat tcctttatcc
      961 cataatgttc cttttcttag tgccagtaca aaggatgccg cactgataat gatccagatc
     1021 aataatactg tatacgaaag ggaacctgcc agatagccaa ataatttgtc accgacaaaa
     1081 taagaaagag ctacaccaag ataaagaaca ctggtacaaa ataaaacagc acgttgcggt
     1141 acttgatgct tgtttaaaac agctagtttt ctagaggaac cttttcgatc cttcaaacgg
     1201 aagaacaaaa ttcttgaaga tgcatacaca cccgaattga tagatgagaa caaagcaagg
     1261 acaatcacaa aattgacgat atccgctgca aatgggatat tcattttttc aaataccatc
     1321 acaaaaggac tgacattcgt gcctgctaaa gtattccaag gaaaaagaat caaaagcaaa
     1381 aacaaaggaa tgatgtaaaa ggaaatgatt cttcccatga cacctttgat tgctttagga
     1441 atcgcacgtt taggatcatc tgcttcgctt accgtgatag caatcagttc agaaccgccg
     1501 taagaataga taactacaag caaagaactg atgattccct tcataccatg aggagtaaac
     1561 ccaccatggt cagtcaattg ctgaagggta gggaaaacgc ctgtgcccaa catttgctga
     1621 ccgacaagat aagtagcaaa aatgatcagt aagataatga cactgatttt agcaaaagcc
     1681 agccaatatt ctgtttctgc gaataaccgt accgaataaa gattgatgat cgtagttaaa
     1741 acagccaaca taaaaacaaa tacccaggct ggaatgtgcg ggaaccacaa ctgcaaaaag
     1801 gaagcagctg caacagcttc agcgatgata ttgataatcc acatagacca gtagacccaa
     1861 tcagtaaaat cagcagaatg agcacctaga taagggcgta tcaaaccaga taatccgtga
     1921 tgcgtgtcgc caccgcttaa aacgattttt cccagacctt tcatcacgat atataaaatc
     1981 agcccaccaa tcaaaaaagc aatcaataca gaagggccgg cgatcccaat cgcttcgcca
     2041 cttcctttaa atagacctgc accgattgct ccacctaaag ctaacatggt gatatgtctg
     2101 gagctaagtt gttttttcaa ttttttatct tccataaatg acctctttct tttaaattca
     2161 caatcaaaat ttatattaag aataaatagc aatatttaac aatgactaat gataacaaat
     2221 tttcagacaa ttacaactat tcagaaaact tttaggcgaa ttttaataga agaatgattt
     2281 atttcatcat attttcatac aaatgttaaa ttttcataca aatataggaa acgttttact
     2341 ggctttttac tatttaaaca ggctatcata ggaaaaagtg acagagaaag tgaggcggaa
     2401 aagatgaaca aaaatgacgt actgctagtt gcaaaaaata aatcacttta ttttttgcct
     2461 tccatccgct ctttagatgt ttggtccgga aaagatttac tacagtcgga attcattaaa
     2521 tcagctagac aacagttggc aaattatcag ctgatcgttt ttttagatta tggatttgat
     2581 atggagatgg ctcgacgcgt gcgcccattt accaatgcaa aaattgtgtt atttttttgg
     2641 aatcacttca aagcagaaca cgaggcgatg ctgaagcagg cacaagatga accggcaatc
     2701 gatgagattt atcattttga ttttttggaa gcaaaagaac ttgggctgaa acataatagt
     2761 tcattttatt cgaaacatat gaatttttct tctagcgaac caaagacgga tctatttttt
     2821 ggtgcaacga ataatgggag aaaagaacga gcagaaagct ataagcagga atttataaaa
     2881 agagatgtta cgaccaacta tttcattctt ccacatcgag ggaatgaaca acctggatat
     2941 cttacttatg aagagtacct gaaaaaaaca ggggaatcgc gcgggattct ggaactgttg
     3001 cgggagggtc agcaaggagt gactttgcgg acatttgaat ccatgtattt tcaaaagaaa
     3061 ctagtgacgg ataatcaagc gattgctcat tatcattttt atcgtcctga aaatattttt
     3121 ttgcttcgag aacgtgattt agatgaatta ccggaatttc tgcatacacc atttaagcca
     3181 atcctatcag agctattgga attttatgat gcagaaaatt gggcaaaacg atttatcact
     3241 aacgattcca ctatttatga gcaatacgaa tatgacctct cctctgttga aaacaaataa
     3301 aaaacctaca ttttgaagag attatgtact gaaacaaaca agcacaattc ttatggcatc
     3361 atgagagttg tgttttcttt ttgatctttt attgggctta aaaaaagaga accagctgct
     3421 gattcagctg attctcatca gagagccttt tattctgcgc caaggattcc ttcttttgca
     3481 tggactaatt gggtcaaaaa ggcacaatat ggtgtagcaa tatcatattt ttgtcctttt
     3541 cgccaaatgg caccattgat gtagtcgatt tcagtcaaac gatggttttt gatcaggtct
     3601 tggtacatag atgggtaatg caacccgatg ttgtcaggat cataagtaga agcaatatgt
     3661 tggtacactt cttcttgatc tagtatgatt ccttcttttg ctgcgataga agcaaattca
     3721 gatacgattg ttcgaaccat gctctctgcc gctttttgcg cgcctagttc agcaatatta
     3781 caatccaaaa tcgtgcataa accattcaat gttccattta cacaagcttt tcgccaaatg
     3841 gaataacgaa cgttatggct atagatcgga tttaaatttg cttcttgaaa gacttctaca
     3901 actttttttg taaatgcttc gccttctggt tccaagttct ctagttcgat ttctccatca
     3961 cctaacaatg tgacttttcc gggaccagct agaccagctg tccacatcgt gatcccaaat
     4021 aagatatttt tctttggcac atatttttcc agtacatctt catgacctaa tccatttagt
     4081 aaacacaaaa cataagtatt gtcagtaata atggattgga tcgaacaaaa catatcatct
     4141 aattgattgg cttttgttaa tgctacgatc aagtccacgt gttcgttgct ttcgatgatt
     4201 tcttctggtg aatagattgg cagttttgcg accacttctt taccgttaaa gtcagcaatc
     4261 aacccatttg tacgaatggc ttcaatgtga gcaggccaac gatcgatcaa gaggacctca
     4321 tttccgcttt gatgtagcat caatccgatt cggctgccca ttgctccggc cccagctatt
     4381 gcgattttca tgttttttct ctcctttatt caatgagttc ccttttagta tatagaaaaa
     4441 tggaagaaaa tagcattgtt ttgtttgaaa aaaatgaaaa aaagtgtctt acttaagaag
     4501 aaagtgaggg atacagatgg atattttggc ggcaattgat tcatttaaag gaagtgcttc
     4561 ttcatttgaa ctaaatcagg cagttctaaa tggctgggaa gatcgtaaag gaagaaaaat
     4621 caatgtgccg attgcagatg gcggagaaaa tactgcagaa gcaatctatt acgcgctcag
     4681 gggaacatgg cgtaccattg atgggatgga tctcttattc cgtcagcgaa aaatcagcta
     4741 tttattgaca acttggcaag gaaaaaacac cgcagtcatc gaatctgcac aagcattggg
     4801 gttagatcta cttgataaac caacggatca aactatccga cttgcttcca gttatgcctt
     4861 aggagaactt attaaagatg cactgcttca agaagtagaa caaattattg tcactttagg
     4921 aggaagcggg tgtagcgatg gtggtctagg attactccaa tccttgggtg cttctttaga
     4981 agggtacaca gaaggaaatc ctttattatc tactaaaaaa cttcattttg atcgaagaaa
     5041 cgttcttgtt tctaaagtaa aattgattat cgctgcagat gttaccaatc catatacagg
     5101 tcaacaagga gctgcttggc aatttggaag acaaaaagga ggaatagata cgacgctagc
     5161 tttcttagat aaacaagcag gaaagattgc tcagcaaata aaagatttct gggaggtgga
     5221 tttagatgat attccaggaa gtggagcagc aggcggtatt ggtggagccc tttttttgtt
     5281 gggagcgaag atggtttctg gtttcgattt agtcagccaa atcactggat tggaaaaaaa
     5341 gatcgaacaa gcagatgtca tcattacagg agaagggcgg atcgatcagc aaacgatcca
     5401 cggaaaagtt ccatacggtg tagcagtgct tgcaaaaaaa tatcgaaaac caataatcgc
     5461 tatttgcgga agtagagacc aagagctaga aggactttct gattttctcc caattgtctt
     5521 aagtattcat ttgggtccaa taggtttaga agaagcaatg gaacacaggc aaacattaga
     5581 aaaaacaaaa atcttaggac agacacttag cagatttttc accatcctcc cgaagtagtt
     5641 gacaaaatca ttttctttat gctatcgtaa tttcaaatat aggacaaagt gagggatccg
     5701 tgcattgaaa aattaagtcg attgatgaaa gctgcattca gactgtacct tgtggagaca
     5761 aggaagcagt gtgcagattt tcgggattgg cttggttttt tcgatgtatg ggtctttttg
     5821 tgtgtatcca acccttgcat cctctttagc cagttctgaa aataggactg gtcttttttt
     5881 acgaggtgat ggaaaatgtc taaaatcgaa ataaaaaatc tgacattcgg ctacgacagc
     5941 caaggcacat tattatttga acaagcaaat ctaaattttg acacacaatg gaaactagga
     6001 cttatcggac gaaacggtcg aggaaagaca actttactga atattctaca aaacaaacta
     6061 ccttatcaag ggcaagtaat ccatcagcaa gaatttgcct atttcccgca acagacaaaa
     6121 gataaagaac gtttaaccta ttacgtgtta aatgatatta cggattttga gatatgggaa
     6181 atcgaaagag agctccaatt gatgcaaaca gatcctgaaa tcttatggag agaattcagc
     6241 acactatcgg ggggagagaa gacaaaagtc ctactggcac ttttatttgt ggatgacact
     6301 catttcccgt taatcgatga accaacgaat catttggata tctctggtag aaaacaagta
     6361 gcggcttatt tgaaaaagaa aaaacaaggc ttcatcgtgg tcagccatga ccggggattt
     6421 atcgatgaag tagtggacca tgttttagca atcgaaaaaa gtcaactgga actttatcaa
     6481 gggaatttct ctatctatga agaacagaaa aaacttcgtg atgaatttga aatggctcaa
     6541 aatgaaaaat tgaaaaaaga agtcagtagg ctaaagaaaa cagcagctga aaaagccgaa
     6601 tggtctcgtt cccgagaagg agataaaaca aagaaacaag tcggattcat cgatactgaa
     6661 tctagacgag tgaataaagg agcagtgggt gctgatgctg cacggacgat gaaacgatcc
     6721 aaagcaatcg tgaatcggat ggagacccag atcagcgaga aagaaaaact attaaaagat
     6781 atcgaatata tcgattcttt gacgatgaat agccaagcgt ctcaccataa gcgactttta
     6841 agcgtagaag atcttcaatt agggtatgaa aatctgttat tcgagccaat tcattttaca
     6901 atcgagcctc atcagcgggt ggcgatttca ggtcctaacg gtgcaggaaa gtcatccatt
     6961 atccattatc ttctgggggc attcaacggc aaggttatag gagaaaaata ccagccaaaa
     7021 catctgagca ttagttatgc aagccaaaat tatgaagaca atcgaggaac gttggcggaa
     7081 tttgcagaga aaaaccaagt agactaccaa gcatttttga acaacctccg aaagcttggg
     7141 atggaaagag atgtttttca taacaagatc gagcagatga gtatgggcca acggaaaaaa
     7201 gtggaattgg ctaaatcttt atcacagcca gctgaactat atacatggga tgaaccattg
     7261 aattatttgg atgtcttcaa tcaagaacaa ttagaacaac tgatcttgaa cgtgaaacct
     7321 gccatgttac tagtggaaca tgatcaaacc ttcctggata aagtatctac tgagattatt
     7381 tctcttgaga gaatctaacc cttgtaatct caagaacaac aaggtatggt taaggggaac
     7441 tttgccaacg aaggagagaa tcacatgctt tatgtaacga gacacggaga aacaacttgg
     7501 aacgcacaag gattagtttg cggacgggca gatgtgccgc tgactgaaaa aggacagatg
     7561 caggcacaga aactagcaga aaaggtagta gatttgcctg ttccaatcac gaaaatcatc
     7621 cattcccctc ttcaacgagc aagagataca gcacaagcag ttgctgatcg tctcagcttg
     7681 ccgctgaccg ttgatgaacg attggtagaa atggattttg gggattatga tggactgcca
     7741 agcaaagatg agaactttca aaaagcacgt ttagcgttcg ctgtacgatt cccaaatggg
     7801 gagtcagtct tagatgtgta tgcacggatc gttcctttat tgaaagaatg catcgaagac
     7861 gaagaaaatg tctatctgtt agtttgccat aatgccttga taagagtgat caatgcttat
     7921 tttcatccga tgcctaatga ggggttcttt acattcatgg tagataatac agaattggtt
     7981 tcttatgagt aattatgttt ttgtgttatt taaataaaat atttcaaggc actgcttttg
     8041 cttagcagtg ccttttttag gttatgacaa ttcttttgat aatataaact caacctttag
     8101 aaatgaaatt taattatttt aataaaagta ttgaaatttt gtttctttag atatatactc
     8161 tagtcataga aatgaagacg gatacagaaa aagagggata atatgtttgg cttttcaata
     8221 tttatgaacg attctttgtc agaagagaag aaacagtata tccgccaaat ggcatccaat
     8281 ggctttgtcg gtattttcac ttccatgcat ataccagaag atgatgtttc ggcatatcaa
     8341 aagcgattga tcgaactagg aagcgaagcg aaaaagaata aactagaatt gatggtcgat
     8401 atttcaggag aggcattgga acgagcgggt ttttcattag aagatctaac gcctttgaaa
     8461 gcaattggtg taacaggttt aagaatggat tatcatattt ccaatcagca gattgccgac
     8521 tggtcacatc aattgaaaat cagtttgaat gctagcacga tcacgcctaa agatatcgat
     8581 gaattgaaag aagcagaagc tgatttctca cagattgaag cttggcataa ttattatcca
     8641 cgtcccgaaa cagggctgga caaagaatgg tatcagaaaa aaaatcaatg gctcaaaatt
     8701 caaggtctcc ttgtccaagg ttttgtacca ggagatacag agttgagagg cccactatat
     8761 caaggattgc caactttgga agaacatcga gggatccatc ctcttgcagg cgctctagat
     8821 ctattagcaa gtaacacgga tattgtttac atcggagatg caggtctgtc agaaaacgtt
     8881 caggagcaat ttgcttcttt ccaaaaagaa cagacagtct tgctccatac ggaacctgta
     8941 gatgaagaat tttacgaata tatattaggg aagcatacga atcggcaaga cgatgcaaga
     9001 gatgtcatac gaagcgtaga tgcacgtttt cgagagattc cgcctatccc agcaagaaat
     9061 acagctacgc gtatgaaagg gtctattact ttagataacg aaaagtattt gcgctatatg
     9121 ggtgagatcc aattaaccaa atatgatttg ccagcggatg aaaaagtgaa tgtagtagct
     9181 aaagttatca aagaagagct accattgatc aaccaaatca aagctggtat gaactatcaa
     9241 tttataagaa aagaaggaag ataaaaatga gcaaaatcaa tttagagaac ctaacaacgg
     9301 aacgcagaaa ccaagaaact tttggattag atgagatgag tatttctcaa gccgttcaac
     9361 taatgaacaa agaagatcag aaagtggccg ctgcggttga aaaagaactg acaagtatcg
     9421 aaccagtgat tgctaacacg attgagtcct ttaaaaaagg tggacgtctg atttatatgg
     9481 gagccggaac aagtggaaga ctaggtgtgt tagatgctgc tgaatgcgta ccgacattcg
     9541 gtgtagaacc ggaaatggtc ataggtctaa ttgctggtgg agaagaagca atgactgtag
     9601 ctgtcgaagg ggccgaagat tcttatgagc tagggcaaga agatctaatc aagctgaatt
     9661 tgacaaaaaa tgatatagtt attggtatcg cagctagcgg tcgtacacca tatgtgatcg
     9721 gtggattaga ttacgcaaaa tcgatcggtg ctgtcacagg aacgatttct tgcaataaac
     9781 aagccgaaat cagtaaacac gcggatttcc caatcgaagt cgatgcaggt ccagaatttt
     9841 tgacaggctc tactcgattg aagtcaggaa cagcacaaaa acttatcttg aatatgattt
     9901 ctactatcag tatgattggt ataggtaaag tattcaataa cttgatggtc gatgtcaaac
     9961 caacaaatga aaaactaatc gaacgctcaa aacgaatcat catgcaagcg acagaagctg
    10021 attacgaaac agctgaaaag tactttgaag aagcagatca aaatgttaag ctggctatcg
    10081 tcatgatttt gacaaatagt gataaagagg aagctcaagc aaaattagct gaagcaaacg
    10141 gatttgtaaa agggacctta tgagggggaa aagaccatgg caaaaaacga actgactttg
    10201 gaagaactgg caaaacaaat ttataaaggg gcaggcggca tgggcaatgt agaaagcatt
    10261 gtccactgca tgactcgtgt gcgtatgaag atcatcaatg atgatcttgt aaatgtctct
    10321 gaattaaaag cgattccagg agtgcttggt gtagtagaag atgaacagct tcaagtcatc
    10381 atcggacctg ggaaagtgaa caaagtagca cagcaaatgg ttgatttggc aggcgtgaaa
    10441 ttaggagaaa aactttcttc tgtaagtaca gctacagcaa attcatcagc atctggaaaa
    10501 gaccgtgtaa acgaacgggc acaagaaatg aaagcggcac aaaaatcgaa acaaaaacca
    10561 tctaaaatca aatcggtatt aaaagacatt tctaatatct ttgtgccaat gattcctgca
    10621 tttgtcggta ctgggatcgt ggcagggatt gccgcagttt tagcaaactt agtcacagcc
    10681 ggaacacttg atgcagcaac atggcaacaa tatatcgatg tgatgaacat cttgaaaaac
    10741 gggatgttta gctacctagt tatctataca ggtatcaatg ctgcacaagt ttttggtgca
    10801 acaccaactc ttggtggagt tatcggggcc gttgtgatgc tgacagggat gaatccggaa
    10861 gcaccactga aaaacttatt tactggtgaa gctcttgcag ctggacaagg tgggatccta
    10921 ggtgtcatct tcgctgtttg gctattgtca atcgttgaga aaaaactgca taaagtagta
    10981 cctgatgcgg tagatatcat cgttacacca actctttcat tgattgccat cggtctgatt
    11041 gaaattttct tcatcatgcc tttagcaggt ttcatttctg atggcatggt cggtgggatc
    11101 aactgggtac ttggcgttgg tggagcattt gccggcttcg ttctaggcac attattcttg
    11161 ccgatggtta tgttcggact gcatcaaatt ttgactccaa tccatgtgca aatgattgat
    11221 gaaactggtc gtacgctatt gcttccaatt cttgcgatgg ctggtgcagg acaagtgggt
    11281 gcagcattgg cattatggat tcgctgcaaa aaagataaag aattaacaga aatgatcaaa
    11341 ggagctttac cagtcgggat cctaggaatc ggcgaaccat tgatttacgg agtaacatta
    11401 cctctaggac gcccatttat tactgcttgt atcggtggag gtatcggcgg ggcagtgatc
    11461 ggaatgatcg gaaatgtcgg ggctatcgct attggacctt caggagccgc tttgat
//
LOCUS       DAPBAF010000168         8968 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.guided.080, whole genome shotgun sequence.
ACCESSION   DAPBAF010000168 DAPBAF010000000
VERSION     DAPBAF010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8968)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8968)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8968
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.guided.080"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(35..262)
                     /locus_tag="RD451_002973"
     CDS             complement(35..262)
                     /locus_tag="RD451_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7568137.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
     gene            complement(271..744)
                     /locus_tag="RD451_002974"
     CDS             complement(271..744)
                     /locus_tag="RD451_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HDT7568138.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            complement(1385..1558)
                     /locus_tag="RD451_002975"
     CDS             complement(1385..1558)
                     /locus_tag="RD451_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7568139.1"
                     /translation="MMKRLYYSLIITIGYLIVSNLGNMVFGISKEFSWTTTLWESLFF
                     FIFVFLLQNYRKK"
     gene            1975..2541
                     /gene="amaP"
                     /locus_tag="RD451_002976"
     CDS             1975..2541
                     /gene="amaP"
                     /locus_tag="RD451_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HDT7568140.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
     gene            2554..2742
                     /locus_tag="RD451_002977"
     CDS             2554..2742
                     /locus_tag="RD451_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HDT7568141.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            2755..3312
                     /locus_tag="RD451_002978"
     CDS             2755..3312
                     /locus_tag="RD451_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HDT7568142.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            3344..3586
                     /locus_tag="RD451_002979"
     CDS             3344..3586
                     /locus_tag="RD451_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HDT7568143.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
     gene            3927..5141
                     /locus_tag="RD451_002980"
     CDS             3927..5141
                     /locus_tag="RD451_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HDT7568144.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
     gene            5172..5390
                     /locus_tag="RD451_002981"
                     /pseudo
     CDS             5172..5390
                     /locus_tag="RD451_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173391.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            5809..6282
                     /gene="dfrF"
                     /locus_tag="RD451_002982"
     CDS             5809..6282
                     /gene="dfrF"
                     /locus_tag="RD451_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrF"
                     /protein_id="HDT7568145.1"
                     /translation="MIGLIVARSKNNVIGKNGNIPWKIKGEQKQFRELTTGNVVIMGR
                     KSYEEIGHPLPNRMNIVVSTTTEYQGDNLVSVKSLEDALLLAKGRDVYISGGYGLFKE
                     ALQIVDKMYITEVDLNIEDGDTFFPEFDINDFEVLIGETLGEEVKYTRTFYVRKK"
     gene            6409..7065
                     /locus_tag="RD451_002983"
     CDS             6409..7065
                     /locus_tag="RD451_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HDT7568146.1"
                     /translation="MNKEWSELNKTMQAQIKKKDTYKRGIDTLLTLRSQLIQTLVSFK
                     EELCREDFNSIPFINADGYHSKTIAYSIWHIFRIEDIVVHTVINEDEQVFFAGNYQER
                     INSPIITTGNELMKQQIADFSKQLNLEELYLYIFEVWESTEKMLERLSYDELKRKIPK
                     ERKGYLESLNVVNDNEKAIWLIDYWCNKDICGLIQMPFSRHWIMHTEACLRIKNKIHS
                     "
     gene            7247..7777
                     /locus_tag="RD451_002984"
     CDS             7247..7777
                     /locus_tag="RD451_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HDT7568147.1"
                     /translation="MRKVVLFIAMSLDGYIADGNGGVAWLNGHGNDNENIDTYTEFTK
                     DIDTVLMGWNTSHQVVTELSPQEWVYNKFTTYVLTHKECNSSQQIHFTSENPVLLLER
                     LKQEAGKDIWICGGANLVQQLVSKNMIDKYYISVIPTLLGNGVRLLGNIDREIKLRLC
                     KTQTYNGITDLIYMRR"
     gene            8323..8565
                     /locus_tag="RD451_002985"
     CDS             8323..8565
                     /locus_tag="RD451_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3781 domain-containing protein"
                     /protein_id="HDT7568148.1"
                     /translation="MENELLENLGRLHTTELGVIRIKKNLSLNVENVIEWCKEKISLS
                     NAEITRKGKNWYITIDNCIITVNAYSYTVITAHKVK"
     gene            8562..>8968
                     /locus_tag="RD451_002986"
     CDS             8562..>8968
                     /locus_tag="RD451_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002606082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HDT7568149.1"
                     /translation="MINFSIKELNAFAVIGQEVELTNYQKKNIQISTQFWRKFNSSLK
                     KAYLSQSGNWVKYAFMERRNGKLYYFCSIPQRTITPEGFLYKEIPSYKYLVVEHIGAM
                     DKIYETYGKIYEEIIPSTSYIGSLSNDVGKEKS"
BASE COUNT         3132 a         1300 c         1778 g         2758 t
ORIGIN      
        1 attatttttt atttactgtt tgttctactt tattttattc ttctggtata gtattcgagt
       61 catttttata ggtcaacaaa tcacctggtt gacactccaa aacttggcag attttttcga
      121 gagtggaaaa acggatggct tttgcttttc cattttttag aatagagatg tttgccatcg
      181 taatgcccac tttctcactc aattcagtca cactcatttt tttttgagct aatactacat
      241 ctaaattaac gataattgcc atgtcgcacc tcacactgtc aaatcatgat ctgtcttaag
      301 taaaatcgca tgttcaagca gtttttccag cacgcttgtt aatgtgtata ctgcaaaagg
      361 aatgaatacg acagcgattc ctaccaacat caaacctgga gcatcgtcta aatccgctac
      421 tttcataaat ttaggaagta agccaaaaaa ggcgaaacca ataaacaaaa tggttcgttc
      481 gatttttttt agtatgttta agctttgagt ggaaaaagct tggttatctt cgattttttt
      541 caatagtttc aataagaaat aagcaataac gatccctagg agaagggcaa agtaaatgac
      601 agaaacaaat aatgtggtct gccaatcaaa attgaatcct ttttcgcttg tagcgatctg
      661 agtataaaaa agtacgccga acaaaataaa tacggcactt atacctaaaa cgacaaattt
      721 taatagcaat gttttaaatt tcatttttat ccctctttta tctttgatag ctaaaatata
      781 gcagaataat tattgtaaaa caactatttt tttatcgaaa aacaataaaa atatatcgtt
      841 tataaaaaat gatagagtat gaaggtgtgg agtgcattta acagcttttt ttgattgtaa
      901 gaaacattta aaaccagtta ttttagattc tatgtgtgtc tcttctataa tgctagttta
      961 gatgcctggg attatattgg acaatacagt tggaggattt tttattatct agcgaagaga
     1021 agtgtaagtt aacagaactg tatgagaaaa aagacaacta cgtagtagct aaccgattca
     1081 ttaatttttt caagttcatg tttatttacg tatcagaatt tttcttattc aatggtttgg
     1141 tgtaatcacc acttatttgt cctttattgc ttatacaatg ttatacaaaa ggaaaatcaa
     1201 gcattgacgc atggggtggt actatctagc tgaaatagct taataagcgc aagtagatgc
     1261 attggattag tttataaatc aaaagtgtta gaggtattaa gaagaagtag aaaaataaaa
     1321 tggattgccg aataaaaagt accataaatc ctaaaacatg tgccaacaga tagatggcac
     1381 atgtttattt ttttcgataa ttttgtaaca aaaatacgaa gatgaaaaag aatagagatt
     1441 cccataatgt agtagtccaa ctgaattctt tactgatacc aaataccata tttcctagat
     1501 ttgatacaat caaatagcca atcgttatga tcaatgaata gtacaatctt ttcatcatag
     1561 gacatacctc gtttttattt ataagaatag tataaaccaa agaagtgaat aagaaaaatg
     1621 ataatataaa aataaagtaa gaacgcatta aagtaactaa agttatttat tgtatttttt
     1681 aattctccga aaaaatttaa taaataaata gaatcttgta ataataactg agcataatct
     1741 ttgcaatttt taatcttgaa taatatcctt taagtatagc cagcaatcaa aagtaaatag
     1801 agaataagta agcaattgtt atttcagtat cagactggca ataaaacgcc gttatgatcc
     1861 agcaatgttt ggtagcgctt tatttactga tgctatgcta actgttcgct atctatactg
     1921 tgattgtcgg tagagttatt tacagggtaa aaataagttt ataggaggtg gaaaatgaat
     1981 aaggggttaa aaataatcgg tgttatcatg agtttactgc tactttcagt atttctagcg
     2041 attgcgttga tcaatgcgcc gtatattatg cctgaacaat tggaacgatt tcgcttcttt
     2101 actttaacga attactacat gcaacaatat attttctggg cagctgtagt atttgccgtt
     2161 cttgctatta tcatcttgct agtcgttctt ttctatccaa agtcaagagg aactttcgtt
     2221 atgaaacggg aagatggcaa actaacaatc gacaaaaaag cgatcgaagg gttggtacgt
     2281 tcccatttac acgaagaaga gttcattcat tcacctaaag tacggatacg ttcaacgaaa
     2341 aatcgaatcc atatccatgt caacggagac ttgaaacgaa cttcttcatt agtagggaaa
     2401 acaggtgtat tgatgcaaga tatcgaagaa gaagtaacta aagtactcgg aacaaaagaa
     2461 acggtcaaag tggcagtcac atacagcggt tatgaagaac aagaagatac aagagactac
     2521 aagcactctc gagtggaata ggagggccaa ataatgaaag aactattttc agcatacaag
     2581 ctccctatta tctttggggg tcttggacta ctgctagctg ttttatggtt aacgattgga
     2641 tttttcaaga cattgttgat cataatcatg acagcaattg gcgcaggaat cggtttttat
     2701 ttgaaacagt caggaatagt tgatcaattt tttaaatcat aggaggaaac aaagatggaa
     2761 aacaaaaaca tgaatacaac aaatggatca gttttggcaa atgaaaaagg agaaaaccgc
     2821 atgatgaatg gtgaattgac ttatgaagac aaagtcatcc aaaaaatcat cggttatgca
     2881 ttgaaagatg tagatggtct attgacatta gatggcggat ttttctcaaa tatggctgaa
     2941 aaattagtca acacagataa cgtaacagca ggtatcaata cagaagtagg taagaaacaa
     3001 gtagctgtgg atctagatgt gatcgtagaa tacggtaaag acatcgaaga tatttacaac
     3061 caaatcaaag aattgatcag tactgaagta aacaatatga cacatttaga tgttatcgaa
     3121 gtgaatgtga atgttgcaga catcaaaaca caagaagaat accaaaaaga tcaagaaaca
     3181 gtacaagaca aagtaacaga agcagcaaaa tccacaggac aatttgcttc acgccaaaca
     3241 gataaagcaa aatctgctgt aggcaaaggt gcacaaaaag tcaaagaaaa taacgaacca
     3301 cgtgtacaat aagaagtaag aagtcagtta ggaggaattt aaaatgggat ttatttgggc
     3361 attaatcgtc ggcggtatca ttggagcaat tgcaggagca atcacgaata aaggatcatc
     3421 aatggggatc atcgcaaaca tcattgctgg tttagtaggt tcagcaattg gacaagcttt
     3481 actaggaact tggggaccaa caattgcagg aatggctatc attccatcat tgatcggtgc
     3541 aatcatttta gtattagtcg tttcattctt tgcacgtaaa ttataagcaa attgaagaaa
     3601 aacttatgtt gaaatgaaga acaaatttga gaaccgtagc gacactcgct gcggttcttt
     3661 tttatatatt ttatatgaag tattctttat tccttatgaa aaaatatctt taaaaataaa
     3721 aaaagacgaa aataaacggt tttctataaa aagaagaccg tttatttttt gtctttattt
     3781 gtgtgaaaaa cgaaaaagag cacaacacat caagctttta ttaattgtct gtcttttata
     3841 aatgcaagta ttaattcaaa aaaacagaag aaaaaaacaa ctacaccttc ttttatactc
     3901 gtaatcgtag aaaggaggcg aaaaaaatga atacattacc tatcaataca ggagatacag
     3961 cattcatgat tttatgtaca gcaatggttt gcctgatgac tcctggtcta gctttttttt
     4021 acggcggatt agcacggaag aataatatac taacgatcat gtctcaatct tttctctccg
     4081 ttgggataac aacgattatg tgggtatttg gtggattcgg attggccttt ggacgggata
     4141 tcggcggtgt tattggaaac ccggcagatt tctttttgat gagacatgtt acaagcttcc
     4201 ccaacatgtt tcatggtgca acgattccat ttttaatgtt ctttctttac caactgatgt
     4261 ttatcgtgat taccgttcct ttgatgacag gagcttttgc agggagattg aatttaaaag
     4321 gctatattat acttgttatt ttttggaatc tgctgattta tttccctgtt tgccactgga
     4381 tatggggtgg cggatttttg gatcagatgg gatttagaga tttcgctggt ggagcagtca
     4441 tccacacgac agctggattc ggctctttag catgtatcct cacacttggt caaagaaaga
     4501 ttcctttagg agaaagaagt cagcatagca gtcttatggc agctgctatc ggtacaggac
     4561 tgctttggtt tggctggttc ggttttaatt ccggtggtgc acttcgagca gatgaacaag
     4621 cagtcaatgc atttggttca acattcatcg ctcttgcatt tgcgatgatt acttggctga
     4681 tcattgcaaa agtaaaagga aatggctttg attttgtcga cgtactaaca ggatccgttg
     4741 ctggattggc agccattacg ccttgtgccg gttatgtaga agcaaaaagt gccatgctga
     4801 ttgggatcat tgcgggtatc gtctgtcatg ctgctgttga ttttcgtaaa aagaaacaat
     4861 gggatgatgc acttgatgtg tggggtgttc atggcatggg cggattcaca ggtacgattc
     4921 tgatagggat ctttgcatct aacagccatt tactaacgaa tccaagcagc tggtacttct
     4981 tagggattca agtgattggt gtcatcatta ctgccgtgta tgcctatgtg ctgacaacag
     5041 tgattttaaa atcggcgatg cactttacaa cgatcactac tacaaaagaa gaacaagaag
     5101 aaggattgga ctttttcttc tttggcaaca aactcaattg aaacaaattc aaatagaaaa
     5161 gaggaagatt catgcaacaa agcaaaacga aaattcctgc aaaaaaatta acgttctttg
     5221 gctttttggc tatgaccatc tcaatggtcg tttcattata tgaatatccc acattcgcga
     5281 cctcaggctt cagcttagta tttttcttgt tattaggcgg tttgctatgg tttatccctg
     5341 tggcattgtg cgcagcagag atggcaacgg tgaaaggatg ggaaaaaggt gtttcccaaa
     5401 caaaaagata ttaagaaaca gcccatgttt acctgcttgc aaacaaaaga atattgctac
     5461 tagactaaga gatactacat aagtgtgttg gtatctcttt tttgttgccg tgaaacagca
     5521 gactatttca tttctgcttg attaccttaa aacttattag tctatggttt gtcaagggct
     5581 tgttgcgtga gaaatgctga atatcaccct ttacaaaaca taggctgata agtaactttt
     5641 caaaagcaga aaagaaatgg caatgcttat aacaatatga tataatgcag atgaagacaa
     5701 aaaaggaatt tgtcgagctg gttagttcga gataattttg agtttgttaa gatgtggtgc
     5761 acttgatgga atcacaggta cgacatcata ttatggagga tgaaatagat gataggtttg
     5821 attgttgcga ggtcaaagaa taatgttata ggcaagaatg gtaatatacc atggaaaata
     5881 aagggagaac aaaagcaatt tagagagtta acaacgggta atgtggttat tatggggcga
     5941 aagtcttatg aagaaatcgg tcatccgttg cctaatagaa tgaatattgt tgtttccacc
     6001 acaacagagt atcaaggaga taatttagtt tcagttaaat cattagaaga tgcattatta
     6061 ttggctaaag gacgagatgt atacatatct ggtggatatg gactatttaa ggaagctttg
     6121 caaatagtag ataaaatgta tatcacagaa gtagatttaa atattgaaga tggagataca
     6181 ttctttccag aatttgatat caatgatttt gaagttttga taggggaaac acttggtgag
     6241 gaagtgaaat atacgagaac attttatgta aggaaaaaat gaattgagta aattttggat
     6301 ttagggtgtt ttcataaata tattgctttt tatgcatata taaattgttg taagacaaat
     6361 tccagtttgt atggggcgat aaaatcagaa tttgagagag gattgaatat gaataaggaa
     6421 tggtctgaac ttaataaaac aatgcaggca caaataaaaa agaaagatac ttataagagg
     6481 ggtattgata ctttacttac tttacgaagt cagttaatac aaaccttagt atctttcaaa
     6541 gaagaattat gcagagaaga ttttaactca atccccttca taaacgctga tggttatcat
     6601 agtaagacga ttgcttattc tatttggcat attttccgca ttgaagatat agttgtgcat
     6661 acagtgataa atgaagatga acaagtattt tttgcaggca attatcaaga gcgtatcaat
     6721 tcacctatca ttacaacagg aaatgaactc atgaaacagc agattgcaga cttttcaaaa
     6781 cagcttaatc tggaagaatt atatttatat attttcgaag tatgggaaag cactgagaaa
     6841 atgcttgaac ggttatctta tgatgaattg aaaagaaaaa taccgaaaga aagaaaagga
     6901 tacttagaat cgttgaatgt agtaaacgac aatgaaaaag caatttggct gattgattat
     6961 tggtgtaata aagatatttg tggactaatt caaatgccgt tttcaagaca ttggattatg
     7021 cacacagaag cctgtttgcg tataaagaac aagatacatt cataggcaaa aatttcagtt
     7081 tgtagaacta aggaaattgg aatttaagga ggaataaagt atggttagtg attttataag
     7141 agcagcattt ccatggattt taatgggttt atttgtagca atcagttgtt cccttatgag
     7201 taaaaaagag aaataaattc ctgtttgtat ttataaaaga gaaaaaatga gaaaagtagt
     7261 tttatttatt gccatgagcc ttgacggata tattgcggac ggtaatggtg gagtagcttg
     7321 gctaaatggt catggaaatg acaatgaaaa catcgacact tatacagaat ttaccaaaga
     7381 tatagatact gtcttaatgg ggtggaatac ttctcatcag gttgttactg aactttctcc
     7441 gcaagaatgg gtatataata aatttacaac ttatgtatta acacataaag agtgcaattc
     7501 ttcccaacaa attcatttta caagtgaaaa tcctgtttta ttattggaac ggctaaaaca
     7561 agaagcagga aaggatattt ggatttgtgg cggagcaaat cttgttcagc agttggtaag
     7621 caaaaatatg attgataaat attacatttc tgttattcct actctgttag gaaatggggt
     7681 tcgtcttttg ggcaacatag acagggaaat aaagttaagg ctttgtaaaa cacagactta
     7741 taacggaata accgatttga tttatatgcg tagataacta gagagaaaca gaaaagctgt
     7801 taaaccgacg gagcgatccg accacgttgg cgggaaaatc cttaagattt ttccgccatg
     7861 cttgcaaggg ggcggttcgc ttcggcggtt cggcgagctt gcgagccgtt caaagccccc
     7921 gttatctaac aaggggggca caaaaaacaa gaaacactat acactaacaa gcggaaaacg
     7981 ctgtatttat aaggcaaaac cccattttta cagtagtgat ataaattgta cctatatcac
     8041 tatgaaaatt gaatagtaaa tatgagaaag acagttgatt tcaaaaaata agaaattgat
     8101 tgtcgttttc ttttgcagaa atttaagtgc aggcaattat ggtagttgtc gtaattgctg
     8161 tcagctcagt gtttatcact gatggtgtga aagatttacg gttggagatg ttcaataaga
     8221 ttattggtgc ttaattattt ttattgtagt gctgatatga gaatgttata attggggtat
     8281 aaaacataca aataaatttg ctgaaaaatg aggtatcaaa atatggaaaa tgaattactg
     8341 gaaaacttag gaagacttca cacaactgaa cttggcgtta ttagaattaa aaagaactta
     8401 tctttgaatg tagaaaatgt aattgaatgg tgcaaagaaa aaattagcct ttctaatgcg
     8461 gaaatcacaa gaaaaggaaa aaactggtat ataacgattg ataattgtat tataacggta
     8521 aatgcgtaca gttataccgt tatcactgct cacaaggtaa aatgataaat ttttctataa
     8581 aggaattaaa cgcatttgca gttattgggc aggaagtaga actgactaat tatcaaaaaa
     8641 agaatattca gattagtaca cagttttgga gaaagtttaa cagtagtttg aaaaaagcgt
     8701 atctttcaca atcaggaaat tgggtaaaat atgcttttat ggaaagaaga aatggaaaac
     8761 tttattattt ctgttctatt ccccaaagaa ccattacccc agagggcttt ctgtataaag
     8821 aaataccgtc ttataaatat ttggttgtgg agcatattgg tgctatggat aaaatatatg
     8881 aaacttatgg caagatttat gaagaaatta ttcctagtac atcgtatatt ggctctttgt
     8941 caaatgatgt tggtaaagag aaatctta
//
LOCUS       DAPBAF010000169         8062 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.guided.084, whole genome shotgun sequence.
ACCESSION   DAPBAF010000169 DAPBAF010000000
VERSION     DAPBAF010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8062)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8062)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8062
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.guided.084"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            128..1564
                     /locus_tag="RD451_002987"
     CDS             128..1564
                     /locus_tag="RD451_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDT7568150.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            1753..4200
                     /locus_tag="RD451_002988"
     CDS             1753..4200
                     /locus_tag="RD451_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HDT7568151.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            4430..5497
                     /gene="rlmN"
                     /locus_tag="RD451_002989"
     CDS             4430..5497
                     /gene="rlmN"
                     /locus_tag="RD451_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HDT7568152.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(5690..6793)
                     /locus_tag="RD451_002990"
     CDS             complement(5690..6793)
                     /locus_tag="RD451_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HDT7568153.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            7346..7894
                     /gene="aac(6')"
                     /locus_tag="RD451_002991"
     CDS             7346..7894
                     /gene="aac(6')"
                     /locus_tag="RD451_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HDT7568154.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         2697 a         1375 c         1751 g         2239 t
ORIGIN      
        1 tttcttacta ctcgaaacta agcgactttt tcacaacctc ctttacataa ttttattttg
       61 ttgtggaagg ggtttcgtgt tattctaaaa gaggaacgat tgaaggttat aggaaaggaa
      121 gagatgaatg gaacacaaag aacttacctc atttccaaaa gattttctgt ggggctctgc
      181 ttctgcagcg tatcaagtag aaggagcttg gcaagaagat gggaaaggag aatcagtctg
      241 ggatcgattt gtacggatac ctggaaagac atttaaagga acgaacggtg atttggcagt
      301 agaccactat catcgttata aagaagatat tgctttaatg aaagaacaag gtctgaaagc
      361 ttaccgcttc tctgtagctt ggacacggat ttttcctaat ggacgaggag aagtcaatca
      421 agctgggctc gctttttatg agagattgat cgacgaattg attgaaaacg atattgaacc
      481 tatgttgact ttatatcatt gggatcttcc acaagcattg caagatgaat ataatggttg
      541 ggaatcacgt cagatcattg aagatttcac tcattatgca gaaacattat ttgaggcatt
      601 ccgcgggaaa gtccattact ggattagttt gaatgaacaa aatatcttca cttcattagg
      661 ttatttgtta gcagcacatc cgccaggtgt gacagacccg aaacgaatgt atgaagttaa
      721 ccatattgct aatttagcaa atgcatctgt catcaataaa tttcacgagt tagaaatgcc
      781 tggaaaaatc ggaccaagct ttgcgtatac gccaaattat ccaattgaca gtaatcctga
      841 aaatgttctg gctgctgaaa atgcagaaga cctgatggcc aattattgga tggatgtcta
      901 tatgtgggga aaatatccga ttgctgccat gaggttctta gaagaaaaag gatgggcacc
      961 aacgattgaa gctggcgatg cagaattgct agaatctgct aaaccagatt ttcttgggat
     1021 caattactat caaacggcga cgaatgcatt caatccatta aacggagttg gtgctggaaa
     1081 aatgaatacg acaggaaaaa aaggttcatc agaagaaact ggagttcctg gaatgtataa
     1141 aaaagttgag aatccatttg tcgaacgaac aaattgggac tgggagattg acccagaagg
     1201 attaaggatc ggactgcgtc gtatcacaag ccgttaccgc atgccggtac tgattacgga
     1261 aaatggctta ggagagtatg acaagttgac agaagataaa caaatccatg acgactatcg
     1321 aatcaattac ttacaaagcc acgtcaaagc catcaaagaa gcaatttcgg atggagcaga
     1381 agtcctaggc tattgcacct ggtcttatac agatttgctt agctggctga acggttatca
     1441 aaagcgatat ggatttgtat atgttgatca agacgaaaca caagaaggat ctttggaacg
     1501 atataagaaa gacagttatt actggtacca aaaactgatt gaagaaaatg gagagaacct
     1561 ttagttcaca tacttaaaac aagaaggtac ggctggatat ggccgtgcct tttcttgata
     1621 aaatcattta gaaattaaga aaaactgtaa aataagctga aaaatgaaag aaagcgtcag
     1681 ttctttcaaa caaaacttta gttcccttac ttttttttgt ataatgaaac ttgatgaaat
     1741 gagggataat aaatggcaca aaagaaacgg cctactaaaa aaaggaaaaa gacgaaaaaa
     1801 acgaaaaagc aaaaacagca gcaggaacaa atgctgacga ttggtgttgg gtttgccttg
     1861 attttatttg ctgtcttcgg ctttttaaaa ttaggttttt taggaatatt gattgcaaac
     1921 ggctttcgga tcattgcagg aaatacttac caaatcctct gtcttttatt agccgtatta
     1981 ggattttgga ttgtcattaa gaatacagag ttttcaattg gtaaaaaccg acgctggttt
     2041 ggcggcatac tcttttattt cggtatctta ttattgttac atgcccattt atttggcaaa
     2101 ctccatactg gggaaccaaa tatcatgggg acgacatggg atttgttagc cagtgatata
     2161 aaacaaagtc aagtagacaa taacgttggt ggtgggatga ttggagcaat cctttatcat
     2221 tttacttact tcttgattgc acagcctgga agttatttag cagcagtgct attactggca
     2281 ggaggagcat tcctgttcag taatctggaa ggctatcagc tgttaaatgg tatccaatca
     2341 attggagaac gagtacagga attattggaa ggtgatcctg ccaagcaagc tcgaaagcaa
     2401 gcggcaaagg aagagagaat gaaacagcgc gcagaagcga aagaagcaag gcgcttagct
     2461 gcaaaagaag ctgcagaaaa agaagctgca gaatatgaga agaaaaaagc ggtgagccag
     2521 caaagggaaa atactgctga tgaatggcag gaaccagaaa atacagagcc ggagcagcta
     2581 agttttgttc caatcgacag ttttcaagaa aatatccatc ctgcgaatct agagaaacca
     2641 gtaccagata caccaaaaca gaccaataca gcagaaggtt tttcagatga gttgccagag
     2701 gatgacggta cctcattaga atttgagatt gaagcagaac aggaaaatca agactatgaa
     2761 ttaccgacag ttgatttgct tgattctata ccaactgtgg atcaaagtga tgagtataaa
     2821 aaaattgaaa aaaatatcgg cgtattagaa caaactttcc aaagtttcgg tgtcgatgcc
     2881 aaggtcgtca aagccagctt aggaccatcc gtcacaaaat tcgaagtcca gccggctgta
     2941 ggggtaaaag taagtaaaat tgtgaactta acagatgata tcgcgcttgc tttagcggcg
     3001 aaagatgtcc ggatggaagc accgattcca ggtaaatcac tgattggtat tgaagtacca
     3061 aatggaaaga tcagtatggt ttcctttaga gaaatcatcg aagcacaacc aaaccaccca
     3121 gataaattac tagaagtacc tttaggacgt gatgtttctg gacgggtaca aacggctgat
     3181 ctttcgaaga tgcctcactt actcgtggct ggttcgactg gtagtgggaa gtcagtagca
     3241 attaatggga ttatcacaag tatattaatg cgtgctaagc cccatgaagt aaaactgatg
     3301 atgatcgatc cgaaaatggt tgaattgaat atgtacaacg gcatacctca tctgttgacg
     3361 ccggtcgtga cgaaccctag aaaagcagcg caagccttac aaaaagtagt acaagaaatg
     3421 gaagaacgat atgaaaaatt cgcggcaacc ggagtaagaa atatttctgg ttacaatgaa
     3481 tttgttcaac agaaaaactt ggaaaacgga acgaaacatc caaccttacc attcatcgta
     3541 gtgatcgtag atgaattagc tgatttgatg atggtagcca gcaatgaagt tgaagatgcg
     3601 attattcgtt tagcgcaaat ggctcgggca gcggggattc atatgatcct agctactcaa
     3661 cgtccaagtg tggatgttat cacaggaatc atcaaagcaa atgtaccttc cagaatggca
     3721 tttgcggtat caagcggtac agattctcgg acgatcattg attctaatgg ggcagaaaag
     3781 ctcttagggc gaggagatat gctattcttg ccaatgggtg agaataaacc gatccgtgtg
     3841 caaggagcat tcatttctga ccacgaagta gaacgggtcg ttcaatttgt tacagatcag
     3901 caagaagctc attatgaaga gaaaatgatg ccgacagatg aagttgaaac gacaggtgct
     3961 ccagaacagc cacaagatga gctgtttgaa gaagcaaaag cacttgtcgt tgaaatgcaa
     4021 acggcaagta tttcccttct ccaaagaaga tttcggatcg gttacaaccg agcagcacgt
     4081 ttagtagatg aactggaagc tcatggagtt gttggcccgt cagaaggaag caagcctcgg
     4141 aaagtattca ttgagcagga agaaacatca gaaacgttgc cggacgataa tgacatgtaa
     4201 aacttgtgtg atgaagggtt gaaaaacgaa taaccaataa aaagacaagg catgatgata
     4261 ccaaaagaaa aaatggtttt tttccatctt ttctaatacg gtatgatgtc ttgtcttttt
     4321 agtttttgtg agattaaagt tctattcgat ttatttgtga agtattgcat taaggaaatg
     4381 aatcatgtat agtatgtagc gaaactttga gaaaaagagg gaaaatactt tggaaaaaca
     4441 gtccatttat ggcttgacga atgaagaatt aatcaattgg tttatagaaa acggcgagaa
     4501 aaaattccga gctgcccaag tttgggaatg gttgtatcaa aaacgtgtaa gtaatttcac
     4561 agaaatgacg aatctatcga aacaattgat cgaaaaatta tcggagcatt ttatcatcaa
     4621 tcctctaaaa cagatggtcg tccaagaagc ttcggatggt acagtaaaat atttgtttga
     4681 actccctgat aaaaacatga ttgagactgt actgatgaga caagaatatg gcttgtcagt
     4741 ttgtgtgacg acacaagtag gatgtaatat cggctgtacg ttttgtgcaa gcgggctgct
     4801 caaaaagaac cgtgatctga ctgctggaga aattgttgca cagatcatga tggtccaaca
     4861 ttattttgat gagcgcaatc ttggcgaacg cgtttcacat gtcgttgtaa tggggatcgg
     4921 tgagccattt gataattacg acaatgtaat ggactttttg catatcatca atgatgccaa
     4981 aggattggca attggtgctc ggcacattac agtttccact agtggattag cacacaaaat
     5041 caaggaattc gctaataacg gcttgcaagt caatctggct atttccttgc acgcgccgaa
     5101 taatgaggtg cgaacatcga tcatgcggat caaccgaagt ttcccaattg agaaattgat
     5161 ggaagctgtg gatgagtatt tagagaaaac aaaccgtcga atcacgtttg aatatatcat
     5221 gttgaatcaa gtaaatgata gaccagagca tgcgcaacaa ttagcagatc tattaaaaga
     5281 taagaaaaaa ttagcatatg tcaacttgat tccatataat ccagtcagtg aacatgatca
     5341 atattctcgc agtccaaaag ctgatgtatt gagattttat gatgtattga agaaaaacgg
     5401 cgtaaactgt gtgatacgta aagaacatgg tacagatatt gatgcagctt gcggacaatt
     5461 gcgaagcaag caaatgaaaa aaacagttgc caaataatcg tatcctactc gttttttcaa
     5521 ttaccataaa aggagcagtt ttcttaatta aggaactgtt caacttaaat aagagaaaag
     5581 attctatagc gaaagctata aagctttttt tgacaagaaa aaccctcatc aagcaaagaa
     5641 atgtcctcaa tttgatgaca gcctgcttga tgggggtttt agcaattatt taactgattt
     5701 tcttatatcc ttgctggctt tcttgtgtag catgataagt ttctacgtca agaatggcct
     5761 gtttaaattt ttctcgggtg atttcataag gcacatgttt aatatcattt gttgccatgg
     5821 ctttatctaa gattgcttct aaatcggtcg tgacattgag attcatgtcg gttaacgata
     5881 ctggaagttg gttctttttc ataaacacat agattttatc aaacaaatcg aactgctgat
     5941 ccatcatcaa taaggtcagt acaccataac tgacagatgc tccgtgaagg tatccctcca
     6001 ttttttctag aacagtcgta ccgtaataga atgagtgtgc catagcagaa ttatagttat
     6061 tgttaactaa aacagaaacc aatccggtag taacaatgat atccgaaacg acttgttcaa
     6121 ttgcatatga gggacgatcg tcggcactat ctttcaatgc ttgcgtacca taagtcaaga
     6181 gacgatcaat gcacattttt ccgatttgga ttcctaatct atccgtgtag cctagatcat
     6241 cgccacgagc agaaaaagta gattcgactt ctttggataa agcatcgcca atacctgccc
     6301 ataagtattt atcaggtgct tcggcaataa ttgctgtatc aatgaaggtg tgtacaggtg
     6361 gttttgaagg aaagaagagt ccgtccatta cgccttcttc gttatagatg acacataccg
     6421 cagtgacggg cgaacagttc gaaccaatag tgggaaaggt gaagactggt ttagctagtt
     6481 tttcaccaat gacttttaca gtatcgcaag cacggccacc accgactgca aacaggacgt
     6541 ctgctttttg gacactttca tgctggatca actgttcaat atttccataa gttgaattac
     6601 ccccgtacca gagactggcg acaacctcta tttcctgtgt caaagctact tttattttgt
     6661 tttctgcctt tgaaagtgca gtcttccctc caatcagcac tacttttgtc ccatattctt
     6721 tgacgattcc atttgctttt tcatacgcat ctgttccaat ggtataattt ggtaagaaaa
     6781 cactttgact catattcatt tccttctttc ttcgttgaaa cgggttaaaa ttttaaagag
     6841 tgatcgatct gactgcggct gtagatggag tagaggtgaa cctaagacag gataagtgat
     6901 gaataaggtg gcatgaacac cttgaaatca tcaataagta tcctaaaaac gaacaagtac
     6961 aaaaacattg aaaacgacaa taatgaattt ttgttcctct tagtatttct accgattccc
     7021 tttgcttttt tgtaattatc taaaaattct aaaaattaag attattatat gaaaacaggt
     7081 tttatttgtc aattcataat tggttttttt taaagcaaaa gataatctat atcatgatga
     7141 acaaacagag ttttttcctc caattgatgg ctttcctgat ctttcctatt ttgaataaag
     7201 tgtttctgta taattttttt attttataag taagataaat aatgaaagaa tagagatact
     7261 gattggtagc taaagatttt tgagcgagaa catttcgttt tttcaaaagg actgttagaa
     7321 taagcaagaa caagggggaa gacgtatgat aatcagtgaa tttgaccgta ataatccagt
     7381 attgaaagat cagctttctg atttactgag actgacttgg ccggaagaat atggagacag
     7441 ctcggcagaa gaagtagaag aaatgatgaa tccagaacga atcgcggtag cagcggtaga
     7501 ccaagatgag ttagtaggat ttattggtgc aatccctcaa tacggtatca caggttggga
     7561 attgcatcca ttagttgtag aaagctcccg acgaaagaac caaataggta ctcgattagt
     7621 caattactta gaaaaagaag tagcttccag aggaggaatc acgatttatt taggtacgga
     7681 tgatttagac catggaacaa cgttaagtca aacggacctg tatgagcata catttgataa
     7741 agtggcttcc atccagaacc ttcgtgaaca tccgtatgaa ttctatgaaa aattaggtta
     7801 taaaatcgta ggtgtcttac caaatgcaaa tggctgggac aaaccggata tttggatggc
     7861 aaaaacgatt attcctcgac caaattctca ataataaaaa gaggttgtga cagaagtaat
     7921 cagcttcaag aaataagaag gaatttacga aaattacttc ttgaattttt gtgaaattcc
     7981 aacttatttc cgaagaagct acttttggaa caccgtgtac cagaggttgt gaaaaagtcg
     8041 cttagtttcg agtagtaaga aa
//
LOCUS       DAPBAF010000170         5211 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.guided.098, whole genome shotgun sequence.
ACCESSION   DAPBAF010000170 DAPBAF010000000
VERSION     DAPBAF010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5211)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5211)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5211
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.guided.098"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            <1..527
                     /locus_tag="RD451_002992"
     CDS             <1..527
                     /locus_tag="RD451_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="lincosamide nucleotidyltransferase Lnu(B)"
                     /protein_id="HDT7568155.1"
                     /translation="DFILYLKLCNRTDSGYIPDTKAMLIYDETGQLENYLSEISGARP
                     NRLTEENANFLLCNFSNLWLMGINVLKRGEYARSLELLSQLQKNTLQLIRMAEKNADN
                     WLNMSKNLEKEISLENYKKFAKTTARLDKVELFEAYKNSLLLVMDLQSHLIEQYNLKV
                     THDILERLLNYISE"
     gene            1215..2036
                     /locus_tag="RD451_002993"
                     /pseudo
     CDS             1215..2036
                     /locus_tag="RD451_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136908.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase zinc beta ribbon domain-containing
                     protein"
     gene            2179..2403
                     /locus_tag="RD451_002994"
     CDS             2179..2403
                     /locus_tag="RD451_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018579902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDT7568156.1"
                     /translation="MTTAEMIKELCEQMNISVSELARRIGQTPQNFNKKLQRETVTLD
                     ELKAIADVLGVKFVQAFILPDGDEIKISNE"
     gene            2418..3287
                     /locus_tag="RD451_002995"
     CDS             2418..3287
                     /locus_tag="RD451_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HDT7568157.1"
                     /translation="MVGNVIQIVTEKLSSLPFIEGIVLGGSRARSTHTENSDIDIGIY
                     YNSDSFDLTAINQIATELDDENRNNLVVPPGAWGDWVNGGGWLVINGCHVDLILRDIK
                     RVEQIIKDTEQGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAEIY
                     PTALKKSLMNFFIFEAEFSLMFVKANAGAEDKYYIAGHVFRIISCLNQVLFACNNAYC
                     INEKKAIKLLETFEYKPEKYAERVNHIFEVLGLSLFECYDMTEKLYKEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            3268..4005
                     /locus_tag="RD451_002996"
     CDS             3268..4005
                     /locus_tag="RD451_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDT7568158.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVD
                     FPEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYN
                     EKGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPP
                     ENMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            4038..4946
                     /gene="ant(6)"
                     /locus_tag="RD451_002997"
     CDS             4038..4946
                     /gene="ant(6)"
                     /locus_tag="RD451_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /protein_id="HDT7568159.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKGLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            4943..5191
                     /locus_tag="RD451_002998"
     CDS             4943..5191
                     /locus_tag="RD451_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin acetyltransferase"
                     /protein_id="HDT7568160.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLLTRGAS"
BASE COUNT         1795 a          772 c         1121 g         1523 t
ORIGIN      
        1 gggattttat tctttattta aaactttgca acagaaccga ttcaggttat attcctgata
       61 cgaaggctat gcttatttac gatgaaacag ggcaattaga aaattattta tcagagataa
      121 gtggtgcaag accaaataga cttactgaag aaaatgctaa ttttttgttg tgtaatttct
      181 ctaatctatg gttgatggga atcaacgttc taaaaagagg agaatatgct cgttcattag
      241 aactcttatc acaacttcaa aaaaatacac tacaacttat acgtatggca gaaaaaaatg
      301 ctgataattg gctaaacatg agtaaaaacc ttgaaaaaga aattagcctt gaaaattata
      361 aaaaatttgc aaagaccact gctcgattag ataaggtaga attatttgaa gcctataaaa
      421 attctttgct attagttatg gatttgcaaa gtcaccttat tgaacaatac aacttaaaag
      481 ttacacatga cattttagaa agattgttga attacattag tgaataggag agtaacgtta
      541 ttcacagtat tgggtactga aaattaacag catacctcag tttttcaaaa aacagcgaag
      601 cctatggata tgttcccgtc taccgatagt gcaaaaagtg tcgtggatat gtttccgaga
      661 acggacatac acaaatgaca ttcattctgt cctctcaatc catgtggaag cagtatgtct
      721 gttaacaaga aaataattat tgttcgtcct gacgagttgt tagactcgaa aaggataaac
      781 atcattttta gaaccggtag ccgatttttg gctagcggtt ttttgggctc tttggcaaat
      841 agtggtgatt gaatctcgcg ctatcctatg gaaaaccgcc ttgtgtgagg ggctgcgaga
      901 ccgcttcgat cctagaattg ctgaagcacg aatctagcgt cactcacatt tcatcttttg
      961 acgtagctga gacaaggtgt ttttcttcga tccgctagtg gttaatctct ttttggtgca
     1021 aatatggttt agaatttctt tgcatggctt aagggagtgg agaatcggat attagtagga
     1081 tttacatcca cagataaaaa taggcttgat tttaacagcg aaactaaaat accctactta
     1141 aatgaagtga tagattagat gttgggttgt taggagatgc ttaaaaatcc tatgcaatca
     1201 atagttttta gtgtttgttg acttgatccc taaatcgcct gagtactaaa cgttgagtgt
     1261 gtctgcttac tgtcactagc cagtaagtga gactgtagtt aatctctcat tttccccagt
     1321 attatgttga aaatagccat gaagcgatta tttctaaaga gttatttttg caggctcaag
     1381 aagaaattta tcggagaagt aatatctaca caggagaagg caagaacaaa agaatttata
     1441 gtagcaagta cgctttaagt gccatcacct tctgtggata ttgtggcgat atttatagga
     1501 gaacctattg gaatattcat ggcagaaaag aatttgtctg gcgatgcgtg actagaatcg
     1561 agcagggtcc cgaggtatgt aagaaccgaa ccgtaaaaga agatgaactc tatggtgcgg
     1621 taatgaccgc aattaataag ctacttgctg gtggcaacaa tatgataaag acactggaag
     1681 aaaatattca tgctgtgatt ggagaaacca cagaatacca aatttcagag attaataccc
     1741 tactagatga aaaacaaaaa gaactaatca agctggccaa taaaggtcaa gattatgaat
     1801 acctggtaga tgagatcgat gagatgcgag ataagcgtca gactctttta gtagaagatg
     1861 cctccctcag tggcgagaac gagcgcatca atgagttgat tgaatttatc cgcaagaaca
     1921 aattccgcac cttagaatat gatgataagc ttgtaaggaa gataatccag aacgttaagg
     1981 tctatgaaga ccacttcgtc atagccttca aaccaggtat cgaaatggaa atatgaaaac
     2041 cagaagtaaa tagcccatga ctctgaagta gagttgtggg ttttctttta attgctgatt
     2101 ataataatat tttaatgact attgcattta tcaaccaaat ggtttatgtt attcttagca
     2161 taaacttgga ggtgctgtat gactacggca gaaatgatta aagaactgtg tgagcaaatg
     2221 aatataagtg tttccgaact tgctagacgt attggccaga ctccacagaa ttttaataaa
     2281 aaattacaac gagaaacagt aaccttggat gagttgaagg ccattgctga tgtgctaggt
     2341 gtcaagtttg tgcaggcatt tattttacca gatggagatg aaataaaaat atctaacgaa
     2401 taaaggagga tgtttatatg gtaggtaatg ttattcaaat agtaacagag aaattatcat
     2461 ctttgccttt tatagaaggc attgtattag ggggctcacg tgcaagaagc acccatacag
     2521 aaaattctga tatagatatc ggaatctatt acaattcaga ctcatttgac ctgacagcga
     2581 ttaatcaaat tgctacagag ttggatgatg agaatagaaa caaccttgtt gtacctcccg
     2641 gagcgtgggg tgattgggtt aatggcggtg gatggttagt tataaacggg tgtcatgttg
     2701 acttgatatt acgtgatata aaacgggtgg aacaaataat caaagatacg gagcaaggaa
     2761 ttgttactgc caattatcag accgggcatc cccatggtta tataagtgct atgtatcgtg
     2821 gagaattagc gattagtaaa atactatatg ctaagaacga aagcttatgc gaattaaaaa
     2881 agcaggcaga aatttaccct actgctctaa agaaaagctt gatgaacttt tttatatttg
     2941 aagctgaatt ctctttaatg tttgtaaaag caaatgcggg ggcagaggat aaatattata
     3001 ttgcaggcca tgtttttcgt attatttcat gcttaaatca agtactattt gcatgtaata
     3061 atgcttattg cattaacgaa aagaaagcta taaaactgct tgaaactttt gaatataaac
     3121 ctgaaaaata tgccgaaaga gttaatcata tttttgaagt actcggtctt tctctttttg
     3181 aatgctacga catgaccgag aaactttata aagaagtgaa tgaaattgta tcggagataa
     3241 ataacttttt aaacgaggag agttcagatg aaagaaaaca aatatgatga taatatattt
     3301 tttcaaaaat acagtcaaat gagtcgctcg cagaaaggac tggctggtgc gggagaatgg
     3361 gagactttga aaaagatgct acctgatttt aagggtaagc gtgtgcttga tttaggatgc
     3421 ggctatggat ggcactgtat tatatatgcg atggaaaacg gtgcttcctc tgtagtaggt
     3481 gttgatattt ctcataaaat gctcgaagta gcaaaaggaa aaacccattt tccacagatt
     3541 gaatatgaat gctgtgccat agaagatgtg gatttcccag aggagagctt tgatgtaata
     3601 ctaagttcgc ttgcgtttca ttatgtagca gactatgaga atttaataaa aaagatatat
     3661 aggatgctga aggctggtgg caatttagtt tttacagttg aacatcctgt ttttactgct
     3721 catggaacac aagactggta ttataacgaa aaaggagaaa tactgcattt cccggtggac
     3781 aattattatt atgagggcaa acggacagct atgtttttgg aagaaaaggt tacaaaatat
     3841 catagaacac tgaccacata tctaaataca ctgctttcaa atagttttat aataaatcag
     3901 attgtggagc cacagccgcc agagaacatg atggatattc cggggatggc ggatgaaatg
     3961 cgacgcccaa tgatgctgat tgtatcggca aaaaagaaga tgtaataata tagaaaaaat
     4021 aaacgaggag tatgtaaatg agatcagaaa aagaaatgat ggatttagta ctttctttag
     4081 cagaacagga tgaacgtatt cgaattgtga cccttgaggg gtcacgcgca aatattaata
     4141 tacctaaaga tgaatttcag gattatgata ttacatattt tgtaagtgat atagaaccgt
     4201 ttatatctaa tgatgactgg cttaatcaat ttgggaatat aataatgatg caaaagccgg
     4261 aggatatgga attattccca cctgaagaaa agggattttc ctatcttatg ctatttgatg
     4321 attacaataa aattgatctt accttattgc ccttggaaga gttagataat tacctaaagg
     4381 gcgataaatt aataaagggt ctaattgata aagattgtag aattaaaagg gacatagttc
     4441 cgactgatat agattatcat gtaagaaagc caagcgcaag ggagtatgat gattgctgca
     4501 atgaattttg gaatgtaaca ccttatgtta ttaaaggatt gtgccgtaag gaaattttat
     4561 ttgctattga tcattttaat cagattgttc gccatgagct gctgagaatg atatcatgga
     4621 aggtcggcat cgaaacaggc tttaaattaa gtgtaggcaa gaactataag tttattgaaa
     4681 ggtatatatc cgaggatttg tgggagaaac ttttgtccac ctaccggatg gattcctatg
     4741 aaaacatatg ggaagcatta tttctatgcc atcaattgtt cagggcggta tccggtgagg
     4801 tggcggaaag gcttcattat gcctatccgg agtatgatag gaatataaca aaatatacca
     4861 gggacatgta taaaaaatac actggtaaaa ccggctgcct ggatagcaca tatgccgctg
     4921 atatagaaga gaggcgggaa cagtgattac agaaatgaaa gcagggcacc tgaaagatat
     4981 cgataaaccc agcgaaccat ttgaggtgat aggtaagatt ataccgaggt atgaaaacga
     5041 gaattggacc tttacagaat tactctatga agcgccatat ttaaaaagct accaagacga
     5101 agaggatgaa gaggatgagg aggcagattg ccttgaatat attgacaata ctgataagat
     5161 aatatatctt ttaacccgtg gtgctagtta attttaatat cctaaagaat a
//
LOCUS       DAPBAF010000171         4790 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.guided.102, whole genome shotgun sequence.
ACCESSION   DAPBAF010000171 DAPBAF010000000
VERSION     DAPBAF010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4790)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4790)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4790
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.guided.102"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            99..794
                     /gene="vanR"
                     /locus_tag="RD451_002999"
     CDS             99..794
                     /gene="vanR"
                     /locus_tag="RD451_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HDT7568161.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            772..1926
                     /locus_tag="RD451_003000"
     CDS             772..1926
                     /locus_tag="RD451_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HDT7568162.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
     gene            2141..3109
                     /locus_tag="RD451_003001"
     CDS             2141..3109
                     /locus_tag="RD451_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HDT7568163.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            3102..4133
                     /gene="vanA"
                     /locus_tag="RD451_003002"
     CDS             3102..4133
                     /gene="vanA"
                     /locus_tag="RD451_003002"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HDT7568164.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAVITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            4139..4747
                     /locus_tag="RD451_003003"
     CDS             4139..4747
                     /locus_tag="RD451_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HDT7568165.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
BASE COUNT         1479 a          917 c         1118 g         1276 t
ORIGIN      
        1 gggattttat tctttattta aaactttgca acagaaccaa ttcggcccta taatctgata
       61 aattattaag ggcaaactta tgtgaaaggg tgataactat gagcgataaa atacttattg
      121 tggatgatga acatgaaatt gccgatttgg ttgaattata cttaaaaaac gagaattata
      181 cggttttcaa atactatacc gccaaagaag cattggaatg tatagacaag tctgagattg
      241 accttgccat attggacatc atgcttcccg gcacaagcgg ccttactatc tgtcaaaaaa
      301 taagggacaa gcacacctat ccgattatca tgctgaccgg gaaagataca gaggtagata
      361 aaattacagg gttaacaatc ggcgcggatg attatataac gaagcccttt cgcccactgg
      421 agttaattgc tcgggtaaag gcccagttgc gccgatacaa aaaattcagt ggagtaaagg
      481 agcagaacga aaatgttatc gtccactccg gccttgtcat taatgttaac acccatgagt
      541 gttatctgaa cgagaagcag ttatccctta ctcccaccga gttttcaata ctgcgaatcc
      601 tctgtgaaaa caaggggaat gtggttagct ccgagctgct atttcatgag atatggggcg
      661 acgaatattt cagcaagagc aacaacacca tcaccgtgca tatccggcat ttgcgcgaaa
      721 aaatgaacga caccattgat aatccgaaat atataaaaac ggtatggggg gttggttata
      781 aaattgaaaa ataaaaaaaa cgactattcc aaactagaac gaaaacttta catgtatatc
      841 gttgcaattg ttgtggtagc aattgtattc gtgttgtata ttcgttcaat gatccgaggg
      901 aaacttgggg attggatctt aagtattttg gaaaacaaat atgacttaaa tcacctggac
      961 gcgatgaaat tatatcaata ttccatacgg aacaatatag atatctttat ttatgtggcg
     1021 attgtcatta gtattcttat tctatgtcgc gtcatgcttt caaaattcgc aaaatacttt
     1081 gacgagataa ataccggcat tgatgtactt attcagaacg aagataaaca aattgagctt
     1141 tctgcggaaa tggatgttat ggaacaaaag ctcaacacat taaaacggac tctggaaaag
     1201 cgagagcagg atgcaaagct ggccgaacaa agaaaaaatg acgttgttat gtacttggcg
     1261 cacgatatta aaacgcccct tacatccatt atcggttatt tgagcctgct tgacgaggct
     1321 ccagacatgc cggtagatca aaaggcaaag tatgtgcata tcacgttgga caaagcgtat
     1381 cgactcgaac agctaatcga cgagtttttt gagattacac ggtataacct acaaacgata
     1441 acgctaacaa aaacgcacat agacctatac tatatgctgg tgcagatgac cgatgaattt
     1501 tatcctcagc tttccgcaca tggaaaacag gcggttattc acgcccccga ggatctgacc
     1561 gtgtccggcg accctgataa actcgcgaga gtctttaaca acattttgaa aaacgccgct
     1621 gcatacagtg aggataacag catcattgac attaccgcgg gcctctccgg ggatgtggtg
     1681 tcaatcgaat tcaagaacac tggaagcatc ccaaaagata agctagctgc catatttgaa
     1741 aagttctata ggctggacaa tgctcgttct tccgatacgg gtggcgcggg acttggattg
     1801 gcgattgcaa aagaaattat tgttcagcat ggagggcaga tttacgcgga aagcaatgat
     1861 aactatacga cgtttagggt agagcttcca gcgatgccag acttggttga taaaaggagg
     1921 tcctaagaga tgtatataat tttttaggaa aatctcaagg ttatctttac tttttcttag
     1981 gaaattaaca atttaatatt aagaaacggc tcgttcttac acggtagact taataccgta
     2041 agaacgagcc gttttcgttc ttcagagaaa gatttgacaa gattaccatt ggcatccccg
     2101 ttttatttgg tgcctttcac agaaagggtt ggtcttaatt atgaataaca tcggcattac
     2161 tgtttatgga tgtgagcagg atgaggcaga tgcattccat gctctttcgc ctcgctttgg
     2221 cgttatggca acgataatta acgccaacgt gtcggaatcc aacgccaaat ccgcgccttt
     2281 caatcaatgt atcagtgtgg gacataaatc agagatttcc gcctctattc ttcttgcgct
     2341 gaagagagcc ggtgtgaaat atatttctac ccgaagcatc ggctgcaatc atatagatac
     2401 aactgctgct aagagaatgg gcatcactgt cgacaatgtg gcgtactcgc cggatagcgt
     2461 tgccgattat actatgatgc taattcttat ggcagtacgc aacgtaaaat cgattgtgcg
     2521 ctctgtggaa aaacatgatt tcaggttgga cagcgaccgt ggcaaggtac tcagcgacat
     2581 gacagttggt gtggtgggaa cgggccagat aggcaaagcg gttattgagc ggctgcgagg
     2641 atttggatgt aaagtgttgg cttatagtcg cagccgaagt atagaggtaa actatgtacc
     2701 gtttgatgag ttgctgcaaa atagcgatat cgttacgctt catgtgccgc tcaatacgga
     2761 tacgcactat attatcagcc acgaacaaat acagagaatg aagcaaggag catttcttat
     2821 caatactggg cgcggtccac ttgtagatac ctatgagttg gttaaagcat tagaaaacgg
     2881 gaaactgggc ggtgccgcat tggatgtatt ggaaggagag gaagagtttt tctactctga
     2941 ttgcacccaa aaaccaattg ataatcaatt tttacttaaa cttcaaagaa tgcctaacgt
     3001 gataatcaca ccgcatacgg cctattatac cgagcaagcg ttgcgtgata ccgttgaaaa
     3061 aaccattaaa aactgtttgg attttgaaag gagacaggag catgaataga ataaaagttg
     3121 caatactgtt tgggggttgc tcagaggagc atgacgtatc ggtaaaatct gcaatagaga
     3181 tagccgctaa cattaataaa gaaaaatacg agccgttata cattggaatt acgaaatctg
     3241 gtgtatggaa aatgtgcgaa aaaccttgcg cggaatggga aaacgacaat tgctattcag
     3301 ctgtactctc gccggataaa aaaatgcacg gattacttgt taaaaagaac catgaatatg
     3361 aaatcaacca tgttgatgta gcattttcag ctttgcatgg caagtcaggt gaagatggat
     3421 ccatacaagg tctgtttgaa ttgtccggta tcccttttgt aggctgcgat attcaaagct
     3481 cagcaatttg tatggacaaa tcgttgacat acatcgttgc gaaaaatgct gggatagcta
     3541 ctcccgcctt ttgggttatt aataaagatg ataggccggt ggcagctacg tttacctatc
     3601 ctgtttttgt taagccggcg cgttcaggct catccttcgg tgtgaaaaaa gtcaatagcg
     3661 cggacgaatt ggactacgca attgaatcgg caagacaata tgacagcaaa atcttaattg
     3721 agcaggctgt ttcgggctgt gaggtcggtt gtgcggtatt gggaaacagt gccgcgttag
     3781 ttgttggcga ggtggaccaa atcaggctgc agtacggaat ctttcgtatt catcaggaag
     3841 tcgagccgga aaaaggctct gaaaacgcag ttataaccgt tcccgcagac ctttcagcag
     3901 aggagcgagg acggatacag gaaacggcaa aaaaaatata taaagcgctc ggctgtagag
     3961 gtctagcccg tgtggatatg tttttacaag ataacggccg cattgtactg aacgaagtca
     4021 atactctgcc cggtttcacg tcatacagtc gttatccccg tatgatggcc gctgcaggta
     4081 ttgcacttcc cgaactgatt gaccgcttga tcgtattagc gttaaagggg tgataagcat
     4141 ggaaatagga tttacttttt tagatgaaat agtacacggt gttcgttggg acgctaaata
     4201 tgccacttgg gataatttca ccggaaaacc ggttgacggt tatgaagtaa atcgcattgt
     4261 agggacatac gagttggctg aatcgctttt gaaggcaaaa gaactggctg ctacccaagg
     4321 gtacggattg cttctatggg acggttaccg tcctaagcgt gctgtaaact gttttatgca
     4381 atgggctgca cagccggaaa ataacctgac aaaggaaagt tattatccca atattgaccg
     4441 aactgagatg atttcaaaag gatacgtggc ttcaaaatca agccatagcc gcggcagtgc
     4501 cattgatctt acgctttatc gattagacac gggtgagctt gtaccaatgg ggagccgatt
     4561 tgattttatg gatgaacgct ctcatcatgc ggcaaatgga atatcatgca atgaagcgca
     4621 aaatcgcaga cgtttgcgct ccatcatgga aaacagtggg tttgaagcat atagcctcga
     4681 atggtggcac tatgtattaa gagacgaacc ataccccaat agctattttg atttccccgt
     4741 taaataaact ttggttctgt tgcaaagttt taaataaaga ataaaatccc
//
LOCUS       DAPBAF010000172         3121 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.guided.114, whole genome shotgun sequence.
ACCESSION   DAPBAF010000172 DAPBAF010000000
VERSION     DAPBAF010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3121)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3121)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3121
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.guided.114"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            <1..1311
                     /locus_tag="RD451_003004"
     CDS             <1..1311
                     /locus_tag="RD451_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional aminoglycoside N-acetyltransferase
                     AAC(6')-Ie/aminoglycoside O-phosphotransferase
                     APH(2'')-Ia"
                     /protein_id="HDT7568166.1"
                     /translation="ESLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYH
                     YPKTDEIVYGMDQFIGEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAI
                     RAYQKSGFRIIEDLPEHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVD
                     SIEIIGSGYDSVAYLVNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIE
                     YSYISDELSILGYKEIKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISE
                     CTIDNKQNVLEEYILLRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSC
                     NHLLLDGNNRLTGIIDFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIE
                     KAKEYQDIVEEYYPIETIVYGIKNIKQEFIENGRKEIYKRTYKD"
     gene            complement(1441..2613)
                     /locus_tag="RD451_003005"
     CDS             complement(1441..2613)
                     /locus_tag="RD451_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
                     /protein_id="HDT7568167.1"
                     /translation="MTQVHFTLKSEEIQSIIEYSVKDDVSKNILTTVFNQLMENQRTE
                     YIQAKEYERTENRQSQRNGYYERSFTTRVGTLELKVPRTRDGHFSPTVFERYQRNEKA
                     LMASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLEPMVNEWQNRLLSEKN
                     YPYLMTDVLYIKVREENRVLSKSCHIAIGITKDGDREIIGFMIQSGESEETWTTFFEY
                     LKERGLQGTELVISDAHKGLVSAIRKSFTNVSWQRCQVHFLRNIFTTIPKKNSKSFRE
                     AVKGIFKFTDINLAREAKNRLIHDYIDQPKYSKACASLDDGFEDAFQYTVQGNSHNRL
                     KSTNLIERLNQEVRRREKIIRIFPNQTSANRLIGAVLMDLHDEWIYSSRKYINFDK"
BASE COUNT         1086 a          405 c          561 g         1069 t
ORIGIN      
        1 gaatcattaa aaaaacatta tacagagcct tgggaagatg aagtttttag agtaattatt
       61 gaatataaca atgttcctat tggatatgga caaatatata aaatgtatga tgagttatat
      121 actgattatc attatccaaa aactgatgag atagtctatg gtatggatca atttatagga
      181 gagccaaatt attggagtaa aggaattggt acaagatata ttaaattgat ttttgaattt
      241 ttgaaaaaag aaagaaatgc taatgcagtt attttagacc ctcataaaaa taatccaaga
      301 gcaataaggg cataccaaaa atctggtttt agaattattg aagatttgcc agaacatgaa
      361 ttacacgagg gcaaaaaaga agattgttat ttaatggaat atagatatga tgataatgcc
      421 acaaatgtta aggcaatgaa atatttaatt gagcattact ttgataattt caaagtagat
      481 agtattgaaa taatcggtag tggttatgat agtgtggcat atttagttaa taatgaatac
      541 atttttaaaa caaaatttag tactaataag aaaaaaggtt atgcaaaaga aaaagcaata
      601 tataattttt taaatacaaa tttagaaact aatgtaaaaa ttcctaatat tgaatattcg
      661 tatattagtg atgaattatc tatactaggt tataaagaaa ttaaaggaac ttttttaaca
      721 ccagaaattt attctactat gtcagaagaa gaacaaaatt tgttaaaacg agatattgcc
      781 agttttttaa gacaaatgca cggtttagat tatacagata ttagtgaatg tactattgat
      841 aataaacaaa atgtattaga agagtatata ttgttgcgtg aaactattta taatgattta
      901 actgatatag aaaaagatta tatagaaagt tttatggaaa gactaaatgc aacaacagtt
      961 tttgagggta aaaagtgttt atgccataat gattttagtt gtaatcatct attgttagat
     1021 ggcaataata gattaactgg aataattgat tttggagatt ctggaattat agatgaatat
     1081 tgtgatttta tatacttact tgaagatagt gaagaagaaa taggaacaaa ttttggagaa
     1141 gatatattaa gaatgtatgg aaatatagat attgagaaag caaaagaata tcaagatata
     1201 gttgaagaat attatcctat tgaaactatt gtttatggaa ttaaaaatat taaacaggaa
     1261 tttatcgaaa atggtagaaa agaaatttat aaaaggactt ataaagattg attatataat
     1321 atatgaaaag ctattataaa agacattagt attaaatagt ttaaaaaaat gaaaaataat
     1381 aaaggaagtg agtcaagtcc agactcctgt gtaaaatgct atacaatgtt tttaccattt
     1441 ctacttatca aaattgatgt attttcttga agaataaatc cattcatcat gtaggtccat
     1501 aagaacggct ccaattaagc gattggctga tgtttgattg gggaagatgc gaataatctt
     1561 ttctcttctg cgtacttctt gattcagtcg ttcaattaga ttggtactct ttagtcgatt
     1621 gtgggaattt ccttgtacgg tatattgaaa ggcgtcttcg aatccatcat ccaatgatgc
     1681 gcaagctttt gaatattttg gttgatcgat ataatcatga atcaatcgat ttttagcctc
     1741 acgcgctaag ttaatatctg tgaacttaaa aattccttta acagcttctc tgaaagattt
     1801 tgaatttttt ttaggaatgg tggtaaagat atttcttagg aagtgaactt ggcatctttg
     1861 ccaacttacg ttggtgaagg attttctaat ggcagagact aatcctttgt gcgcatcaga
     1921 aataacgagt tccgtacctt gtaaaccgcg ttcttttagg tattcaaaaa atgttgtcca
     1981 ggtctcttcg ctttcgccac tttgaatcat gaagccgata atttcacggt cgccatcttt
     2041 ggttattcca atcgctatat gacagctttt tgagagtact cgattttctt ctcgtacttt
     2101 tatatagagt acatcggtca ttaagtaagg ataatttttt tctgataata aacgattctg
     2161 ccactcgtta accataggtt ctagctgttc tgttaagcta gaaacgaagg acttagagac
     2221 ggatttacca caaagttctt ccacaatttt tgatacttta cgagttgaaa cgcctgatac
     2281 atacatttcc aacattgaag ccatgagggc tttttcgttt cgttgataac gttcaaacac
     2341 tgtgggtgaa aaatggccat cacgtgttct gggtactttt aattctagcg tgcctacacg
     2401 tgtcgtaaag ctgcgctcat aatagccatt tcgttgactt tgtcggtttt ctgttcgttc
     2461 atattctttt gcttgaatat attctgttcg ttgattttcc attagttgat taaataccgt
     2521 tgttaaaata tttttagaaa cgtcatcctt tacagaatat tcaataatgc tttgaatctc
     2581 ttcgcttttc agtgtaaaat gtacttgggt catgtaaaag tcctcctggg tatgtttttg
     2641 tcgttaaaaa cattgtaccg taaaaggact gttatatggc ctttttactt ttacacaatt
     2701 atacggactt tatctatata aaggcgctgt cagagttttt tgacttagaa catacattca
     2761 ttcaagagac tttaaacaag ctagcagaac gcccaaaaac ggacacacaa ctcgatttgt
     2821 ttagctatga tacaggctga aaataaaacc cgcactatgc cattacattt atatctatga
     2881 tacgtgtttg tttttctgta ctgtttcctg agtgattagc agaaatataa agattaaaat
     2941 tttaattgat tattaggaag agaaggagaa tgtatcccga aaacttttta gttggcttgg
     3001 actgaacgaa gtgagggaaa ggctactaaa acgtcgaggg gagtgggagc gaagcgcaca
     3061 cttgatcttt tgaacttttt tcggttctgt tgcaaagttt taaatctact atcaaataag
     3121 g
//
LOCUS       DAPBAF010000173         3010 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.guided.116, whole genome shotgun sequence.
ACCESSION   DAPBAF010000173 DAPBAF010000000
VERSION     DAPBAF010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3010)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3010)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3010
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.guided.116"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            60..110
                     /locus_tag="RD451_003006"
                     /pseudo
     CDS             60..110
                     /locus_tag="RD451_003006"
                     /inference="COORDINATES: protein motif:HMM:NF019662.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance efflux system leader
                     peptide"
     gene            144..1520
                     /gene="tet(L)"
                     /locus_tag="RD451_003007"
     CDS             144..1520
                     /gene="tet(L)"
                     /locus_tag="RD451_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001574277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(L)"
                     /protein_id="HDT7568168.1"
                     /translation="MNTSYSQSNLRHNQILIWLCILSFFSVLNEMVLNVSLPDIANDF
                     NKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSF
                     FSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGG
                     MIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFT
                     TSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFV
                     SMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLS
                     VSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFT
                     SFLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNV
                     YKHSQRDF"
     gene            2115..2426
                     /locus_tag="RD451_003008"
                     /pseudo
     CDS             2115..2426
                     /locus_tag="RD451_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000277654.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
     gene            2561..2968
                     /locus_tag="RD451_003009"
                     /pseudo
     CDS             2561..2968
                     /locus_tag="RD451_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000143686.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type A chloramphenicol O-acetyltransferase"
BASE COUNT         1008 a          399 c          559 g         1044 t
ORIGIN      
        1 tattttttaa taaagatttg aattaaagtg taaaggagga attaattatg aagtgaaatg
       61 aatgtaacag ggttcaatta aaagagggaa gcgtatcatt aaccctataa actacgtctg
      121 ccctcattat tggagggtga aatgtgaata catcctattc acaatcgaat ttacgacaca
      181 accaaatttt aatttggctt tgcattttat ctttttttag cgtattaaat gaaatggttt
      241 tgaacgtctc attacctgat attgcaaatg attttaataa accacctgcg agtacaaact
      301 gggtgaacac agcctttatg ttaacctttt ccattggaac agctgtatat ggaaagctat
      361 ctgatcaatt aggcatcaaa aggttactcc tatttggaat tataataaat tgtttcgggt
      421 cggtaattgg gtttgttggc cattctttct tttccttact tattatggct cgttttattc
      481 aaggggctgg tgcagctgca tttccagcac tcgtaatggt tgtagttgcg cgctatattc
      541 caaaggaaaa taggggtaaa gcatttggtc ttattggatc gatagtagcc atgggagaag
      601 gagtcggtcc agcgattggt ggaatgatag cccattatat tcattggtcc tatcttctac
      661 tcattcctat gataacaatt atcactgttc cgtttcttat gaaattatta aagaaagaag
      721 taaggataaa aggtcatttt gatatcaaag gaattatact aatgtctgta ggcattgtat
      781 tttttatgtt gtttacaaca tcatatagca tttcttttct tatcgttagc gtgctgtcat
      841 tcctgatatt tgtaaaacat atcaggaaag taacagatcc ttttgttgat cccggattag
      901 ggaaaaatat accttttatg attggagttc tttgtggggg aattatattt ggaacagtag
      961 cagggtttgt ctctatggtt ccttatatga tgaaagatgt tcaccagcta agtactgccg
     1021 aaatcggaag tgtaattatt ttccctggaa caatgagtgt cattattttc ggctacattg
     1081 gtgggatact tgttgataga agaggtcctt tatacgtgtt aaacatcgga gttacatttc
     1141 tttctgttag ctttttaact gcttcctttc ttttagaaac aacatcatgg ttcatgacaa
     1201 ttataatcgt atttgtttta ggtgggcttt cgttcaccaa aacagttata tcaacaattg
     1261 tttcaagtag cttgaaacag caggaagctg gtgctggaat gagtttgctt aactttacca
     1321 gctttttatc agagggaaca ggtattgcaa ttgtaggtgg tttattatcc atacccttac
     1381 ttgatcaaag gttgttacct atggaagttg atcagtcaac ttatctgtat agtaatttgt
     1441 tattactttt ttcaggaatc attgtcatta gttggctggt taccttgaat gtatataaac
     1501 attctcaaag ggatttctaa atcgttaagg gatcaacttt gggagagagt tcaaaattga
     1561 tccttttttt ataacaggaa ttcaaatctt tttgttccat taaagggcgc gattgctgaa
     1621 taaaagatac gagagacctc tcttgtatct tttttatttt gagtggtttt gtccgttaca
     1681 ctagaaaacc gaaagacaat aaaaatttta ttcttgctga gtctggcttt cggtaagcta
     1741 gacaaaacgg acaaaataaa aattggcaag ggtttaaagg tggagatttt ttgagtgatc
     1801 ttctcaaaaa atactacctg tcccttgctg atttttaaac gagcacgaga gcaaaacccc
     1861 cctttgctga ggtggcagag ggcaggtttt tttgtttctt ttttctcgta aaaaaaagaa
     1921 aggtcttaaa ggttttatgg ttttggtcgg cactgccgac agcctcgcag agcccacctt
     1981 tacgaagtaa agtatagtgt gttatacttt acatggaagt tgtaccgaaa tattgtgttg
     2041 tgaagtctat ataattttaa aattatgaag tctatatacg tgcgtaaaga tatttaaaga
     2101 gattaaaaat aataaaaata aaaattgaat taaaaagaga tatggttgat tattggaacg
     2161 attgttttaa tgatttacat atattacaac cagattggaa aactatcgaa cgtacttctg
     2221 atagagcaat ggtttttatg ttgttgaatg atgaagaaga atggggaaaa ttagaaagac
     2281 gtactaagaa taaatataaa aaattaatta aagaaatatc tctaattgat ttaactgatt
     2341 taatgaaatc gactttaaaa gcgaacgaaa aacaattgca aaagcagatt gatttttggc
     2401 aacgtgaatt tagattttgg aagtaaagta actttgtttt atacaaaatg ttactttagt
     2461 ataattaacg tttaagaggt gacacaatat atgaaaaaat cagaggatta ttcctcctaa
     2521 atacaaagag ataagatgaa atttaggagg aaaattatat atgactttta atattattaa
     2581 tttggaaact tgggatagaa aagaatattt taatcattat ttcaatcaac aaacaactta
     2641 cagtgttact aaagaatttg atatcacttt acttaaaagt atgataaaaa ataaaggata
     2701 tgaactgtat cctgctttga tttatacaat tgtaaatatt ataaatcaaa ataaagtatt
     2761 tagaacagga attaatagtg agggaaattt gggttattgg gaaaaattaa accctttata
     2821 tacagtcttt aataaagaaa ctgaaaaatt ttctaacatt tggacagaat caaatgttag
     2881 ttttaattct ttttataata gttataagag tgacttactt gaatataaag ataaaaatga
     2941 aatgtttcct aaaaaaccaa tacctgaaaa ggttctgttg caaagtttta aataaagaat
     3001 aaaatccctt
//
LOCUS       DAPBAF010000174         2567 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.guided.123, whole genome shotgun sequence.
ACCESSION   DAPBAF010000174 DAPBAF010000000
VERSION     DAPBAF010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2567)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2567)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2567
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.guided.123"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            complement(41..343)
                     /locus_tag="RD451_003010"
                     /pseudo
     CDS             complement(41..343)
                     /locus_tag="RD451_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327954.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1057..1347)
                     /locus_tag="RD451_003011"
     CDS             complement(1057..1347)
                     /locus_tag="RD451_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDT7568169.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            complement(1555..2246)
                     /locus_tag="RD451_003012"
                     /pseudo
     CDS             complement(1555..2246)
                     /locus_tag="RD451_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
BASE COUNT          759 a          472 c          357 g          979 t
ORIGIN      
        1 gtatggattt tttcatttac acaaaatatt ttatactctc aacatacttg caaagtaata
       61 ctacaattcc taacataatc gtagaattta ataatttcca tagcataaag tgtttagaaa
      121 agaacattaa gaatagttct ataataattc ttgaactcca tgtcttataa tgttctatcg
      181 aagcacccaa atagccaagt tcatctaatc tacttgcata aactacgtca tccgctctca
      241 tagtcggcat atacatatta aagagtaaaa agatacccca aatccctatt agtaacaaga
      301 tcagttcttt gttattcgtt atttttctat tatgtttgtt catttttata ctccttctta
      361 tatttcctaa tagagtataa catagcttta agcattactt aaagataact taaaagttat
      421 cttttaaata cttaattgtt aaatacctta tttgatgcaa aagaaatcta cgatagtcaa
      481 caaaaaaatt ttcattatat ccagaaaaat ttttcttagt taaggaccta tggattgcag
      541 taatgcagaa ttcgtcgaat aaactgccaa agacatacaa tcatattgct tttaaaattg
      601 acgaacaaga tatagattcg tttgtctcaa aaatccaaat gttaggttta actgtcgaac
      661 caggacgttc tcgtgtgaaa ggcgaggctt cttcaattta cttttacgac tatgataatc
      721 acctcttcga gttacatacc ggtactctcc aggaacgttt aaaatcctac aattccacta
      781 cctgagacta gtaatgacta gtctcttttt atggcctctg atccccccat tgagcgaata
      841 ctaatagggc ttcgaattga tctgttcaat ctttaagcaa tatccctcaa atgagtttgg
      901 aaagtttagt gattcatcac aaatacttaa atacatgtag ttatatatag attgaggttc
      961 ttgtgagcgt atgctcgtgt gggttcaaat cccatcgtct gcatccatct ttccaaaaca
     1021 agcggctagg acatttttgt ctcagccgct tgttttctag tttattcttt catcttgtcg
     1081 gacctttttt cttgggtata gacttttctc atattctacc acaattttgg gtttccctaa
     1141 cacatgatag gatctcacaa caaattgctt tctattatta taataacctg taacgactaa
     1201 cttcatccct tcgtctactt cagctaggaa gttcaaacta tgggaagcaa tcaaacaatt
     1261 gaccccattt aaactgaaac ggatcaacgg tctggcacta acttgcaaag tacggatctt
     1321 atctactgtt ccatattttt tctccataac cttcacctca ataccattat acgaacatac
     1381 attccctttg taaagaagaa actctgtttt atctttttga ctttttgtct attacctttc
     1441 ttaaaatcat attggcactt cctgcgaaga tgaaggacat gtactaaaaa aaagaggcag
     1501 cagtatagat tactgttgct tctttactaa tttaggttta cttgttaaga aagattattt
     1561 acgcaaatgt tcttcaacaa tttgctgaga tttatcagct gtatcttcca cttcatcttt
     1621 tgctttttct aacttttgaa tatattgttt caagcttgag ttttcagcag ttgcttcgtc
     1681 taatttcttt tgtgtatctg ttaactgatt tctacatttg ttttttcttg tgtcagtgtt
     1741 gcgatttgtt gattcaaacc atttacagta ttttgtaatt ctgaaagttt tgcttgtgct
     1801 tcttgtagtc ttgctgtcca atctgcattc agatgattga tttcatcatt tttttggttg
     1861 atctcatcta gtttgacatt gatttcattt tgtttgcttt gtagttgtgc atccttgctg
     1921 actaattgac tttctaagtt ttgtttttct gctgccgatt gatttttttg gttttctaat
     1981 tcatttactt ttgtttggta ttcttggaca tctgcctttg aatcttgcaa tgtctgttct
     2041 ttttgtgcta gtcgagcggt aagatctgta atcgcttgct ctttatctgt caatgtatga
     2101 tcaagctgtg tcagattctc attgattgta tcaatatctg tctctccacc ccacaaaata
     2161 atttcatttg cgtaccgcgt gcctgtgtag ccaattagac atagaaatgc aacgacaatc
     2221 ccaccagtaa taaatttctt tttcatttgc atagctcctt aatccaatac ttttacatgc
     2281 taaaagtaag tgatctcaaa cacaatgtca agcgttttta aattacatat gtaattttaa
     2341 tataaatact atcaaatact catttaatcc tcctttttta tctatttaaa aaatcttttt
     2401 tatagagaaa aatgcaggtt aatactttct taaataaata tttatggtga acaaaaacaa
     2461 aaaagcaagt tttattaaac gtaacccttt tcatttcata gattactgta tttattacaa
     2521 aaaacgcgga tttgtcataa attgtcatgc ttcttttacc tatgaaa
//
LOCUS       DAPBAF010000175         2100 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.guided.128, whole genome shotgun sequence.
ACCESSION   DAPBAF010000175 DAPBAF010000000
VERSION     DAPBAF010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2100)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2100)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2100
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.guided.128"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            <1..75
                     /locus_tag="RD451_003013"
     CDS             <1..75
                     /locus_tag="RD451_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HDT7568170.1"
                     /translation="PMVMHKNPSDKSIYHWDFYALLGF"
     gene            91..2010
                     /gene="tet(M)"
                     /locus_tag="RD451_003014"
     CDS             91..2010
                     /gene="tet(M)"
                     /locus_tag="RD451_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HDT7568171.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSMEIIIKQKVEL
                     HPNMCVMSCTEPEQWDVVIEGNDDLLEKYMSGKSLEALELEQEEIRRFQNCSLYPVYH
                     GSAKSNIGIEQLIEVITNKFYSSTYRKKSELCGNVFKIEYSEERQRLAYVRLYGGILH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLQYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
BASE COUNT          720 a          320 c          436 g          624 t
ORIGIN      
        1 cctatggtta tgcataaaaa tcccagtgat aaaagtattt atcactggga tttttatgcc
       61 cttttgggtt tttgaatgga ggaaaatcac atgaaaatta ttaatattgg agttttagct
      121 catgttgatg caggaaaaac taccttaaca gaaagcttat tatataacag tggagcgatt
      181 acagaattag gaagcgtgga caaaggtaca acgaggacgg ataatacgct tttagaacgt
      241 cagagaggaa ttacaattca gacaggaata acctcttttc agtgggaaaa tacgaaggtg
      301 aacatcatag acacgccagg acatatggat ttcttagcag aagtatatcg ttcattatca
      361 gttttagatg gggcaattct actgatttct gcaaaagatg gcgtacaagc acaaactcgt
      421 atattatttc atgcacttag gaaaatgggg attcccacaa tcttttttat caataagatt
      481 gaccaaaatg gaattgattt atcaacggtt tatcaggata ttaaagagaa actttctatg
      541 gaaattataa tcaaacagaa agtagagctg caccctaata tgtgtgtgat gagctgtacg
      601 gaacctgagc aatgggatgt ggtaatagaa ggaaatgatg accttttaga gaaatatatg
      661 tccggtaaat cattagaagc attagaactc gaacaagagg aaatcagaag atttcagaat
      721 tgctccttgt accctgttta tcatggaagc gcaaaaagca acatagggat tgagcagctt
      781 atagaagtga taacgaataa attttattca tcaacataca gaaagaagtc tgaactttgc
      841 ggaaatgtct tcaaaattga atattcggaa gaaagacaac gtcttgcata tgtacgcctt
      901 tatggcggaa tcctgcattt gcgggattcg gttagaatat cggaaaagga aaaaataaaa
      961 attacagaaa tgtatacttc aataaatggt gaattatgta aaattgataa ggcttattcc
     1021 ggggaaattg ttattttgca aaatgagttt ttgaagctaa atagtgttct tggagataca
     1081 aagctattgc cacagagaga gagaattgaa aatccgctcc ctctgctgca aacaactgtt
     1141 gaaccgagca aacctcaaca aagggaaatg ttacttgatg cacttttaga aatctccgac
     1201 agtgacccgc ttctacaata ttatgtggat tctacgacac atgaaattat actttctttc
     1261 ttagggaaag tacaaatgga agtgattagt gcactgttgc aagaaaagta tcatgtggag
     1321 atagaactaa aagagcctac agtcatttat atggagagac cgttaaaaaa tgcagaatat
     1381 accattcaca tcgaagtgcc gccaaatcct ttctgggctt ccattggttt atctgtatca
     1441 ccgcttccgt tgggaagtgg aatgcagtat gagagctcgg tttctcttgg atacttaaat
     1501 caatcatttc aaaatgcagt tatggaaggg atacgctatg gttgcgaaca aggattatat
     1561 ggttggaatg tgacggattg taaaatctgt tttaagtatg gcttatacta tagccctgtt
     1621 agtaccccag cagattttcg gatgcttgct cctattgtat tggaacaagt cttaaaaaaa
     1681 gctggaacag aattgttaga gccatatctt agttttaaaa tttatgcgcc acaggaatat
     1741 ctttcacgag catacaacga tgctcctaaa tattgtgcga acatcgtaga cactcaattg
     1801 aaaaataatg aggtcattct tagtggagaa atccctgctc ggtgtattca agaatatcgt
     1861 agtgatttaa ctttctttac aaatggacgt agtgtttgtt taacagagtt aaaagggtac
     1921 catgttacta ccggtgaacc tgtttgccag ccccgtcgtc caaatagtcg gatagataaa
     1981 gtacgatata tgttcaataa aataacttag tgtattttat gttgttatat aaatatggtt
     2041 tcttgttaaa taagatgaaa tattttttaa taaagatttg aattaaagtg taaaggagga
//
LOCUS       DAPBAF010000176         2100 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.guided.129, whole genome shotgun sequence.
ACCESSION   DAPBAF010000176 DAPBAF010000000
VERSION     DAPBAF010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2100)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2100)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2100
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.guided.129"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            <1..75
                     /locus_tag="RD451_003015"
     CDS             <1..75
                     /locus_tag="RD451_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HDT7568172.1"
                     /translation="PMVMHKNPSDKSIYHWDFYALLGF"
     gene            91..2010
                     /gene="tet(M)"
                     /locus_tag="RD451_003016"
     CDS             91..2010
                     /gene="tet(M)"
                     /locus_tag="RD451_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HDT7568173.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLFPLYH
                     GSAKSNIGIDNLIEVITNKFYSSTHRGPSELCGNVFKIEYTKKRQRLAYIRLYSGVLH
                     LRDSVRVSEKEKIKVTEMYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRKKIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
BASE COUNT          722 a          316 c          425 g          637 t
ORIGIN      
        1 cctatggtta tgcataaaaa tcccagtgat aaaagtattt atcactggga tttttatgcc
       61 cttttgggtt tttgaatgga ggaaaatcac atgaaaatta ttaatattgg agttttagct
      121 catgttgatg caggaaaaac taccttaaca gaaagcttat tatataacag tggagcgatt
      181 acagaattag gaagcgtgga caaaggtaca acgaggacgg ataatacgct tttagaacgt
      241 cagagaggaa ttacaattca gacaggaata acctcttttc agtgggaaaa tacgaaggtg
      301 aacatcatag acacgccagg acatatggat ttcttagcag aagtatatcg ttcattatca
      361 gttttagatg gggcaattct actgatttct gcaaaagatg gcgtacaagc acaaactcgt
      421 atattatttc atgcacttag gaaaatgggg attcccacaa tcttttttat caataagatt
      481 gaccaaaatg gaattgattt atcaacggtt tatcaggata ttaaagagaa actttctgcc
      541 gaaattgtaa tcaaacagaa ggtagaactg tatcctaata tgtgtgtgac gaactttacc
      601 gaatctgaac aatgggatac ggtaatagag ggaaacgatg accttttaga gaaatatatg
      661 tccggtaaat cattagaagc attggaactc gaacaagagg aaagcataag atttcagaat
      721 tgttctctgt tccctcttta tcatggaagt gcaaaaagta atatagggat tgataacctt
      781 atagaagtta ttactaataa attttattca tcaacacatc gaggtccgtc tgaactttgc
      841 ggaaatgttt tcaaaattga atatacaaaa aaaagacaac gtcttgcata tatacgcctt
      901 tatagtggag tactacattt acgagattcg gttagagtat cagaaaaaga aaaaataaaa
      961 gttacagaaa tgtatacttc aataaatggt gaattatgta agattgatag agcttattct
     1021 ggagaaattg ttattttgca aaatgagttt ttgaagttaa atagtgttct tggagataca
     1081 aaactattgc cacagagaaa aaagattgaa aatccgcacc ctctactaca aacaactgtt
     1141 gaaccgagta aacctgaaca gagagaaatg ttgcttgatg cccttttgga aatctcagat
     1201 agtgatccgc ttctacgata ttacgtggat tctacgacac atgaaattat actttctttc
     1261 ttagggaaag tacaaatgga agtgattagt gcactgttgc aagaaaagta tcatgtggag
     1321 atagaactaa aagagcctac agtcatttat atggagagac cgttaaaaaa tgcagaatat
     1381 accattcaca tcgaagtgcc gccaaatcct ttctgggctt ccattggttt atctgtatca
     1441 ccgcttccgt tgggaagtgg aatgcagtat gagagctcgg tttctcttgg atacttaaat
     1501 caatcgtttc aaaatgcagt tatggagggg atacgctatg gctgtgaaca aggattgtat
     1561 ggttggaatg tgacggactg taaaatctgt tttaagtatg gcttatacta tagccctgtt
     1621 agtaccccag cagattttcg gatgcttgct cctattgtat tggaacaagt cttaaaaaaa
     1681 gctggaacag aattgttaga gccatatctt agttttaaaa tttatgcgcc acaggaatat
     1741 ctttcacgag catacaacga tgctcctaaa tattgtgcga acatcgtaga cactcaattg
     1801 aaaaataatg aggtcattct tagtggagaa atccctgctc ggtgtattca agaatatcgt
     1861 agtgatttaa ctttctttac aaatggacgt agtgtttgtt taacagagtt aaaagggtac
     1921 catgttacta ccggtgaacc tgtttgccag ccccgtcgtc caaatagtcg gatagataaa
     1981 gtacgatata tgttcaataa aataacttag tgtattttat gttgttatat aaatatggtt
     2041 tcttgttaaa taagatgaaa tattttttaa taaagatttg aattaaagtg taaaggagga
//
LOCUS       DAPBAF010000177         1504 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.guided.140, whole genome shotgun sequence.
ACCESSION   DAPBAF010000177 DAPBAF010000000
VERSION     DAPBAF010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1504)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1504)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1504
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.guided.140"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            262..345
                     /locus_tag="RD451_003017"
                     /pseudo
     CDS             262..345
                     /locus_tag="RD451_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000527320.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
     gene            394..477
                     /locus_tag="RD451_003018"
     CDS             394..477
                     /locus_tag="RD451_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuator leader
                     peptide ErmL"
                     /protein_id="HDT7568174.1"
                     /translation="MLVFQMRYVDKTSTVLKQTKNSDYADK"
     gene            602..1339
                     /gene="erm(B)"
                     /locus_tag="RD451_003019"
     CDS             602..1339
                     /gene="erm(B)"
                     /locus_tag="RD451_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HDT7568175.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESRASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
BASE COUNT          551 a          224 c          245 g          484 t
ORIGIN      
        1 atttgtatcg ataagaaata gatttaaaaa tttcgctgtt attttgtaca tttaacttga
       61 cggtgacatc tctctattgt gagttattag tggtacagtt ttcaaccgtt ttaattataa
      121 aaaagtggtg catttttaaa ttggcacaaa caggtaacgg ttattgcagg tgtatttctt
      181 atctatgggt ttaacatgga ttttatcatt aaaatcatga gtattgtccg agagtgattg
      241 gtcttgcgta tggttaaccc taaagttatg gaaataagac ttagaagcaa acttaagagt
      301 gtgttgatag tgcattatct taaaattttg tataatagga attgaagtta aattagatgc
      361 taaaaatttg taattaagaa ggagggattc gtcatgttgg tattccaaat gcgttatgta
      421 gataaaacat ctactgtttt gaaacagact aaaaacagtg attacgcaga taaataaata
      481 cgttagatta attcctacca gtgactaatc ttatgacttt ttaaacagat aactaaaatt
      541 acaaacaaat cgtttaactt ctgtatttgt ttatagatgt aatcacttca ggagtgataa
      601 catgaacaaa aatataaaat attctcaaaa ctttttaacg agtgaaaaag tactcaacca
      661 aataataaaa caattgaatt taaaagaaac cgataccgtt tacgaaattg gaacaggtaa
      721 agggcattta acgacgaaac tggctaaaat aagtaaacag gtaacgtcta ttgaattaga
      781 cagtcatcta ttcaacttat cgtcagaaaa attaaaactg aatactcgtg tcactttaat
      841 tcaccaagat attctacagt ttcaattccc taacaaacag aggtataaaa ttgttgggaa
      901 tattccttac catttaagca cacaaattat taaaaaagtg gtttttgaaa gccgtgcgtc
      961 tgacatctat ctgattgttg aagaaggatt ctacaagcgt accttggata ttcaccgaac
     1021 actagggttg ctcttgcaca ctcaagtctc gattcagcaa ttgcttaagc tgccagcgga
     1081 atgctttcat cctaaaccaa aagtaaacag tgtcttaata aaacttaccc gccataccac
     1141 agatgttcca gataaatatt ggaagctata tacgtacttt gtttcaaaat gggtcaatcg
     1201 agaatatcgt caactgttta ctaaaaatca gtttcatcaa gcaatgaaac acgccaaagt
     1261 aaacaattta agtaccgtta cttatgagca agtattgtct atttttaata gttatctatt
     1321 atttaacggg aggaaataat tctatgagtc gcttttgtaa atttggaaag ttacacgtta
     1381 ctaaagggaa tgtagataaa ttattaggta tagggcacct ctaataacta ccaattaatt
     1441 cacctcaaaa tgaaattaga aaaaaacagc gaaattttta aatctatttc ttatcgatac
     1501 aaat
//
LOCUS       DAPBAF010000178         1418 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.guided.144, whole genome shotgun sequence.
ACCESSION   DAPBAF010000178 DAPBAF010000000
VERSION     DAPBAF010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1418)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1418)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1418
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.guided.144"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            <1..152
                     /locus_tag="RD451_003020"
     CDS             <1..152
                     /locus_tag="RD451_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDT7568176.1"
                     /translation="YSKEIGCSEMFLITDKGNPRACHVYEKLGGKNDYKDEIVYVYDY
                     EKGDK"
     gene            153..>1418
                     /gene="aac(6')-Ie"
                     /locus_tag="RD451_003021"
     CDS             153..>1418
                     /gene="aac(6')-Ie"
                     /locus_tag="RD451_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012655884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ie"
                     /protein_id="HDT7568177.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYDGRDKKYTLE
                     SLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFI
                     GEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLP
                     EHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYL
                     VNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKE
                     IKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYIL
                     LRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGII
                     DFGDSGIIDEYCDFIYLLEDSEEEIGTNFG"
BASE COUNT          589 a          106 c          247 g          476 t
ORIGIN      
        1 aatattctaa agagattggt tgttctgaaa tgtttttaat aactgataaa ggtaatccta
       61 gagcttgcca tgtatatgaa aaattaggtg gtaaaaatga ttataaagat gaaatagtat
      121 atgtatatga ttatgaaaaa ggtgataaat aaatgaatat agttgaaaat gaaatatgta
      181 taagaacttt aatagatgat gattttcctt tgatgttaaa atggttaact gatgaaagag
      241 tattagaatt ttatgatggt agagataaaa aatatacatt agaatcatta aaaaaacatt
      301 atacagagcc ttgggaagat gaagttttta gagtaattat tgaatataac aatgttccta
      361 ttggatatgg acaaatatat aaaatgtatg atgagttata tactgattat cattatccaa
      421 aaactgatga gatagtctat ggtatggatc aatttatagg agagccaaat tattggagta
      481 aaggaattgg tacaagatat attaaattga tttttgaatt tttgaaaaaa gaaagaaatg
      541 ctaatgcagt tattttagac cctcataaaa ataatccaag agcaataagg gcataccaaa
      601 aatctggttt tagaattatt gaagatttgc cagaacatga attacacgag ggcaaaaaag
      661 aagattgtta tttaatggaa tatagatatg atgataatgc cacaaatgtt aaggcaatga
      721 aatatttaat tgagcattac tttgataatt tcaaagtaga tagtattgaa ataatcggta
      781 gtggttatga tagtgtggca tatttagtta ataatgaata catttttaaa acaaaattta
      841 gtactaataa gaaaaaaggt tatgcaaaag aaaaagcaat atataatttt ttaaatacaa
      901 atttagaaac taatgtaaaa attcctaata ttgaatattc gtatattagt gatgaattat
      961 ctatactagg ttataaagaa attaaaggaa cttttttaac accagaaatt tattctacta
     1021 tgtcagaaga agaacaaaat ttgttaaaac gagatattgc cagtttttta agacaaatgc
     1081 acggtttaga ttatacagat attagtgaat gtactattga taataaacaa aatgtattag
     1141 aagagtatat attgttgcgt gaaactattt ataatgattt aactgatata gaaaaagatt
     1201 atatagaaag ttttatggaa agactaaatg caacaacagt ttttgagggt aaaaagtgtt
     1261 tatgccataa tgattttagt tgtaatcatc tattgttaga tggcaataat agattaactg
     1321 gaataattga ttttggagat tctggaatta tagatgaata ttgtgatttt atatacttac
     1381 ttgaagatag tgaagaagaa ataggaacaa attttgga
//
LOCUS       DAPBAF010000179         1349 bp    DNA     linear   BCT 29-AUG-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate VRE_DUN_024
            SAMN36683371-rid18909973.guided.146, whole genome shotgun sequence.
ACCESSION   DAPBAF010000179 DAPBAF010000000
VERSION     DAPBAF010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36683371
            Sequence Read Archive: SRR25390941
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1349)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1349)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (28-JUL-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 28-JUL-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001831704.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001831704.1
            Genome Coverage       :: 103x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 07/28/2023 20:57:50
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,023
            CDSs (total)                      :: 2,950
            Genes (coding)                    :: 2,879
            CDSs (with protein)               :: 2,879
            Genes (RNA)                       :: 73
            rRNAs                             :: 3, 2, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 3 (16S, 23S)
            tRNAs                             :: 61
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 28 of 71
            Pseudo Genes (incomplete)         :: 39 of 71
            Pseudo Genes (internal stop)      :: 13 of 71
            Pseudo Genes (multiple problems)  :: 8 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1349
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36683371-rid18909973.guided.146"
                     /isolate="VRE_DUN_024"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="United Kingdom: Dundee"
                     /lat_lon="56.46 N 2.97 W"
                     /collection_date="2015-03"
                     /collected_by="NHS Tayside"
                     /note="genotype: vanA"
     gene            46..297
                     /locus_tag="RD451_003022"
                     /pseudo
     CDS             46..297
                     /locus_tag="RD451_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            390..1184
                     /locus_tag="RD451_003023"
                     /note="aph(3')-IIIa"
     CDS             390..1184
                     /locus_tag="RD451_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HDT7568178.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
BASE COUNT          424 a          234 c          322 g          369 t
ORIGIN      
        1 cattttcctc taggaaaaaa ttaactagca ccacgggtta tcttttatat agaagatatc
       61 gccgtatgta aggatttcag ggggcaaggc ataggcagcg cgcttatcaa tatatctata
      121 gaatgggcaa agcataaaaa cttgcatgga ctaatgcttg aaacccagga caataacctt
      181 atagcttgta aattctatca taattgtggt ttcaaaatcg gctccgtcga tactatgtta
      241 tacgccaact ttgaaaacaa ctttgaaaaa gctgttttct ggtatttaag gttttagaat
      301 gcaaggaaca gtgaattgga gttcgtcttg ttataattag cttcttgggg tatctttaaa
      361 tactgtagaa aagaggaagg aaataataaa tggctaaaat gagaatatca ccggaattga
      421 aaaaactgat cgaaaaatac cgctgcgtaa aagatacgga aggaatgtct cctgctaagg
      481 tatataagct ggtgggagaa aatgaaaacc tatatttaaa aatgacggac agccggtata
      541 aagggaccac ctatgatgtg gaacgggaaa aggacatgat gctatggctg gaaggaaagc
      601 tgcctgttcc aaaggtcctg cactttgaac ggcatgatgg ctggagcaat ctgctcatga
      661 gtgaggccga tggcgtcctt tgctcggaag agtatgaaga tgaacaaagc cctgaaaaga
      721 ttatcgagct gtatgcggag tgcatcaggc tctttcactc catcgacata tcggattgtc
      781 cctatacgaa tagcttagac agccgcttag ccgaattgga ttacttactg aataacgatc
      841 tggccgatgt ggattgcgaa aactgggaag aagacactcc atttaaagat ccgcgcgagc
      901 tgtatgattt tttaaagacg gaaaagcccg aagaggaact tgtcttttcc cacggcgacc
      961 tgggagacag caacatcttt gtgaaagatg gcaaagtaag tggctttatt gatcttggga
     1021 gaagcggcag ggcggacaag tggtatgaca ttgccttctg cgtccggtcg atcagggagg
     1081 atatcgggga agaacagtat gtcgagctat tttttgactt actggggatc aagcctgatt
     1141 gggagaaaat aaaatattat attttactgg atgaattgtt ttagtaccta gatttagatg
     1201 tctaaaaagc tttaactaca agctttttag acatctaatc ttttctgaag tacatccgca
     1261 actgtccata ctctgatgtt ttatatcttt tctaaaagtt cgctagatag gggtcccgag
     1321 cgcctacgag gaatttgtat cgataagaa
//
